LOCUS       DACGMI010000001       118154 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.001, whole genome shotgun sequence.
ACCESSION   DACGMI010000001 DACGMI010000000
VERSION     DACGMI010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 118154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 118154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..118154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.001"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(290..1087)
                     /locus_tag="IXT46_000001"
     CDS             complement(290..1087)
                     /locus_tag="IXT46_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAQ4945953.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(1084..2268)
                     /locus_tag="IXT46_000002"
     CDS             complement(1084..2268)
                     /locus_tag="IXT46_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAQ4945954.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(2293..3540)
                     /locus_tag="IXT46_000003"
     CDS             complement(2293..3540)
                     /locus_tag="IXT46_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAQ4945955.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            3755..5500
                     /gene="dnaX"
                     /locus_tag="IXT46_000004"
     CDS             3755..5500
                     /gene="dnaX"
                     /locus_tag="IXT46_000004"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAQ4945956.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            5520..5834
                     /locus_tag="IXT46_000005"
     CDS             5520..5834
                     /locus_tag="IXT46_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAQ4945957.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            5859..6455
                     /gene="recR"
                     /locus_tag="IXT46_000006"
     CDS             5859..6455
                     /gene="recR"
                     /locus_tag="IXT46_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAQ4945958.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            6519..7163
                     /locus_tag="IXT46_000007"
     CDS             6519..7163
                     /locus_tag="IXT46_000007"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAQ4945959.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            7178..7507
                     /locus_tag="IXT46_000008"
     CDS             7178..7507
                     /locus_tag="IXT46_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4945960.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            7521..8459
                     /gene="holB"
                     /locus_tag="IXT46_000009"
     CDS             7521..8459
                     /gene="holB"
                     /locus_tag="IXT46_000009"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAQ4945961.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            8495..9319
                     /locus_tag="IXT46_000010"
     CDS             8495..9319
                     /locus_tag="IXT46_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAQ4945962.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            9312..9659
                     /locus_tag="IXT46_000011"
     CDS             9312..9659
                     /locus_tag="IXT46_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAQ4945963.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            9728..10600
                     /gene="rsmI"
                     /locus_tag="IXT46_000012"
     CDS             9728..10600
                     /gene="rsmI"
                     /locus_tag="IXT46_000012"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAQ4945964.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            10709..11830
                     /gene="dinB"
                     /locus_tag="IXT46_000013"
     CDS             10709..11830
                     /gene="dinB"
                     /locus_tag="IXT46_000013"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAQ4945965.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(11884..12486)
                     /gene="nrdG"
                     /locus_tag="IXT46_000014"
     CDS             complement(11884..12486)
                     /gene="nrdG"
                     /locus_tag="IXT46_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAQ4945966.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(12801..14990)
                     /gene="nrdD"
                     /locus_tag="IXT46_000015"
     CDS             complement(12801..14990)
                     /gene="nrdD"
                     /locus_tag="IXT46_000015"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAQ4945967.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            15316..16083
                     /locus_tag="IXT46_000016"
     CDS             15316..16083
                     /locus_tag="IXT46_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4945968.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            16073..18115
                     /locus_tag="IXT46_000017"
     CDS             16073..18115
                     /locus_tag="IXT46_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4945969.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            18396..18545
                     /locus_tag="IXT46_000018"
     CDS             18396..18545
                     /locus_tag="IXT46_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAQ4945970.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            18556..20070
                     /gene="dltA"
                     /locus_tag="IXT46_000019"
     CDS             18556..20070
                     /gene="dltA"
                     /locus_tag="IXT46_000019"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAQ4945971.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            20067..21272
                     /gene="dltB"
                     /locus_tag="IXT46_000020"
     CDS             20067..21272
                     /gene="dltB"
                     /locus_tag="IXT46_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAQ4945972.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            21317..21550
                     /gene="dltC"
                     /locus_tag="IXT46_000021"
     CDS             21317..21550
                     /gene="dltC"
                     /locus_tag="IXT46_000021"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAQ4945973.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            21553..22821
                     /gene="dltD"
                     /locus_tag="IXT46_000022"
     CDS             21553..22821
                     /gene="dltD"
                     /locus_tag="IXT46_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAQ4945974.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            22962..24044
                     /locus_tag="IXT46_000023"
     CDS             22962..24044
                     /locus_tag="IXT46_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAQ4945975.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            24044..24847
                     /locus_tag="IXT46_000024"
     CDS             24044..24847
                     /locus_tag="IXT46_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAQ4945976.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            24917..25657
                     /locus_tag="IXT46_000025"
     CDS             24917..25657
                     /locus_tag="IXT46_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4945977.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            25668..26672
                     /locus_tag="IXT46_000026"
     CDS             25668..26672
                     /locus_tag="IXT46_000026"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAQ4945978.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(26717..28561)
                     /locus_tag="IXT46_000027"
     CDS             complement(26717..28561)
                     /locus_tag="IXT46_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4945979.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            28773..29291
                     /locus_tag="IXT46_000028"
     CDS             28773..29291
                     /locus_tag="IXT46_000028"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4945980.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            29419..30102
                     /locus_tag="IXT46_000029"
     CDS             29419..30102
                     /locus_tag="IXT46_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAQ4945981.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            30411..30484
                     /locus_tag="IXT46_000030"
     tRNA            30411..30484
                     /locus_tag="IXT46_000030"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30445..30447,aa:Arg,seq:tct)
     gene            30643..31002
                     /locus_tag="IXT46_000031"
     CDS             30643..31002
                     /locus_tag="IXT46_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAQ4945982.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            31125..32756
                     /locus_tag="IXT46_000032"
     CDS             31125..32756
                     /locus_tag="IXT46_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAQ4945983.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(32818..33459)
                     /locus_tag="IXT46_000033"
     CDS             complement(32818..33459)
                     /locus_tag="IXT46_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAQ4945984.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            33741..34049
                     /gene="rplU"
                     /locus_tag="IXT46_000034"
     CDS             33741..34049
                     /gene="rplU"
                     /locus_tag="IXT46_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAQ4945985.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            34076..34420
                     /locus_tag="IXT46_000035"
     CDS             34076..34420
                     /locus_tag="IXT46_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAQ4945986.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            34433..34726
                     /gene="rpmA"
                     /locus_tag="IXT46_000036"
     CDS             34433..34726
                     /gene="rpmA"
                     /locus_tag="IXT46_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAQ4945987.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            35133..37967
                     /locus_tag="IXT46_000037"
     CDS             35133..37967
                     /locus_tag="IXT46_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4945988.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
     gene            38158..38649
                     /locus_tag="IXT46_000038"
     CDS             38158..38649
                     /locus_tag="IXT46_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAQ4945989.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            38752..39741
                     /gene="manX"
                     /locus_tag="IXT46_000039"
     CDS             38752..39741
                     /gene="manX"
                     /locus_tag="IXT46_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAQ4945990.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            39774..40577
                     /locus_tag="IXT46_000040"
     CDS             39774..40577
                     /locus_tag="IXT46_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAQ4945991.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            40598..41512
                     /locus_tag="IXT46_000041"
     CDS             40598..41512
                     /locus_tag="IXT46_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAQ4945992.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVERWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            41595..41969
                     /locus_tag="IXT46_000042"
     CDS             41595..41969
                     /locus_tag="IXT46_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAQ4945993.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            42108..42353
                     /locus_tag="IXT46_000043"
     CDS             42108..42353
                     /locus_tag="IXT46_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4945994.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVVSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            42525..43589
                     /locus_tag="IXT46_000044"
     CDS             42525..43589
                     /locus_tag="IXT46_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAQ4945995.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            43835..44260
                     /locus_tag="IXT46_000045"
     CDS             43835..44260
                     /locus_tag="IXT46_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4945996.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            44253..44702
                     /gene="nusB"
                     /locus_tag="IXT46_000046"
     CDS             44253..44702
                     /gene="nusB"
                     /locus_tag="IXT46_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAQ4945997.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            44799..45653
                     /locus_tag="IXT46_000047"
     CDS             44799..45653
                     /locus_tag="IXT46_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAQ4945998.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            45654..46991
                     /locus_tag="IXT46_000048"
     CDS             45654..46991
                     /locus_tag="IXT46_000048"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAQ4945999.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            46996..47220
                     /locus_tag="IXT46_000049"
     CDS             46996..47220
                     /locus_tag="IXT46_000049"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAQ4946000.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            47222..48112
                     /locus_tag="IXT46_000050"
     CDS             47222..48112
                     /locus_tag="IXT46_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAQ4946001.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            48121..48939
                     /locus_tag="IXT46_000051"
     CDS             48121..48939
                     /locus_tag="IXT46_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAQ4946002.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            49046..49495
                     /locus_tag="IXT46_000052"
     CDS             49046..49495
                     /locus_tag="IXT46_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAQ4946003.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            49513..51195
                     /gene="recN"
                     /locus_tag="IXT46_000053"
     CDS             49513..51195
                     /gene="recN"
                     /locus_tag="IXT46_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAQ4946004.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(51250..51366)
                     /locus_tag="IXT46_000054"
     CDS             complement(51250..51366)
                     /locus_tag="IXT46_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAQ4946005.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(51439..52395)
                     /locus_tag="IXT46_000055"
     CDS             complement(51439..52395)
                     /locus_tag="IXT46_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAQ4946006.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            52566..52934
                     /locus_tag="IXT46_000056"
     CDS             52566..52934
                     /locus_tag="IXT46_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAQ4946007.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            53104..53535
                     /gene="mraZ"
                     /locus_tag="IXT46_000057"
     CDS             53104..53535
                     /gene="mraZ"
                     /locus_tag="IXT46_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAQ4946008.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            53556..54515
                     /gene="rsmH"
                     /locus_tag="IXT46_000058"
     CDS             53556..54515
                     /gene="rsmH"
                     /locus_tag="IXT46_000058"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAQ4946009.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            54520..54921
                     /gene="ftsL"
                     /locus_tag="IXT46_000059"
     CDS             54520..54921
                     /gene="ftsL"
                     /locus_tag="IXT46_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAQ4946010.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            54922..57114
                     /locus_tag="IXT46_000060"
     CDS             54922..57114
                     /locus_tag="IXT46_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAQ4946011.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGMFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            57140..58102
                     /locus_tag="IXT46_000061"
     CDS             57140..58102
                     /locus_tag="IXT46_000061"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAQ4946012.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            58116..59477
                     /locus_tag="IXT46_000062"
     CDS             58116..59477
                     /locus_tag="IXT46_000062"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAQ4946013.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYRHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            59503..60591
                     /gene="murG"
                     /locus_tag="IXT46_000063"
     CDS             59503..60591
                     /gene="murG"
                     /locus_tag="IXT46_000063"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAQ4946014.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            60606..61826
                     /locus_tag="IXT46_000064"
     CDS             60606..61826
                     /locus_tag="IXT46_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAQ4946015.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            61982..63307
                     /gene="ftsA"
                     /locus_tag="IXT46_000065"
     CDS             61982..63307
                     /gene="ftsA"
                     /locus_tag="IXT46_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAQ4946016.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            63330..64571
                     /gene="ftsZ"
                     /locus_tag="IXT46_000066"
     CDS             63330..64571
                     /gene="ftsZ"
                     /locus_tag="IXT46_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAQ4946017.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            64588..65265
                     /locus_tag="IXT46_000067"
     CDS             64588..65265
                     /locus_tag="IXT46_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAQ4946018.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            65279..65878
                     /locus_tag="IXT46_000068"
     CDS             65279..65878
                     /locus_tag="IXT46_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAQ4946019.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            65893..66180
                     /locus_tag="IXT46_000069"
     CDS             65893..66180
                     /locus_tag="IXT46_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAQ4946020.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            66229..67011
                     /locus_tag="IXT46_000070"
     CDS             66229..67011
                     /locus_tag="IXT46_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAQ4946021.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            67032..67739
                     /locus_tag="IXT46_000071"
     CDS             67032..67739
                     /locus_tag="IXT46_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAQ4946022.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            68001..70799
                     /gene="ileS"
                     /locus_tag="IXT46_000072"
     CDS             68001..70799
                     /gene="ileS"
                     /locus_tag="IXT46_000072"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAQ4946023.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(70848..72374)
                     /locus_tag="IXT46_000073"
     CDS             complement(70848..72374)
                     /locus_tag="IXT46_000073"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAQ4946024.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(72389..73036)
                     /locus_tag="IXT46_000074"
     CDS             complement(72389..73036)
                     /locus_tag="IXT46_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAQ4946025.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(73220..73549)
                     /locus_tag="IXT46_000075"
     CDS             complement(73220..73549)
                     /locus_tag="IXT46_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAQ4946026.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            73726..74454
                     /gene="sfsA"
                     /locus_tag="IXT46_000076"
     CDS             73726..74454
                     /gene="sfsA"
                     /locus_tag="IXT46_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAQ4946027.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            74470..75483
                     /locus_tag="IXT46_000077"
     CDS             74470..75483
                     /locus_tag="IXT46_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4946028.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            75483..76760
                     /locus_tag="IXT46_000078"
     CDS             75483..76760
                     /locus_tag="IXT46_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAQ4946029.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            76823..79525
                     /locus_tag="IXT46_000079"
     CDS             76823..79525
                     /locus_tag="IXT46_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4946030.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            79677..79994
                     /locus_tag="IXT46_000080"
     CDS             79677..79994
                     /locus_tag="IXT46_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4946031.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            80024..80344
                     /locus_tag="IXT46_000081"
     CDS             80024..80344
                     /locus_tag="IXT46_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4946032.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            80452..81912
                     /locus_tag="IXT46_000082"
     CDS             80452..81912
                     /locus_tag="IXT46_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4946033.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            81980..82201
                     /locus_tag="IXT46_000083"
     CDS             81980..82201
                     /locus_tag="IXT46_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946034.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            82232..82414
                     /locus_tag="IXT46_000084"
     CDS             82232..82414
                     /locus_tag="IXT46_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAQ4946035.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            82414..82827
                     /locus_tag="IXT46_000085"
     CDS             82414..82827
                     /locus_tag="IXT46_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAQ4946036.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            82950..84131
                     /locus_tag="IXT46_000086"
     CDS             82950..84131
                     /locus_tag="IXT46_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4946037.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            84520..84593
                     /locus_tag="IXT46_000087"
     tRNA            84520..84593
                     /locus_tag="IXT46_000087"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:84554..84556,aa:Arg,seq:cct)
     gene            complement(84662..85801)
                     /locus_tag="IXT46_000088"
     CDS             complement(84662..85801)
                     /locus_tag="IXT46_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4946038.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(85915..86499)
                     /locus_tag="IXT46_000089"
     CDS             complement(85915..86499)
                     /locus_tag="IXT46_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HAQ4946039.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(86582..87004)
                     /locus_tag="IXT46_000090"
     CDS             complement(86582..87004)
                     /locus_tag="IXT46_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAQ4946040.1"
                     /translation="MYLKLKEMLSEYNLKLIYMEMEEPGFYYPKPRIVFLNEKLHEDS
                     SEAFHLAHELGHFIASHFEYSVLYDNSTTFHSKFETEADKIAIMILLNIFIENELTDE
                     SQFKLENFMEFYAINNKLRTECFNVCQSYFKKKYSYAQ"
     gene            complement(87022..87342)
                     /locus_tag="IXT46_000091"
     CDS             complement(87022..87342)
                     /locus_tag="IXT46_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4946041.1"
                     /translation="MNTYEIIKELAKEKGLSIRQLEMNFGYSNGYLGSWKRQTPNSIE
                     LARLADYFGVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            88080..88337
                     /locus_tag="IXT46_000092"
     CDS             88080..88337
                     /locus_tag="IXT46_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HAQ4946042.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(88308..88616)
                     /locus_tag="IXT46_000093"
     CDS             complement(88308..88616)
                     /locus_tag="IXT46_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946043.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            88694..89440
                     /locus_tag="IXT46_000094"
     CDS             88694..89440
                     /locus_tag="IXT46_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAQ4946044.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            89455..89658
                     /locus_tag="IXT46_000095"
     CDS             89455..89658
                     /locus_tag="IXT46_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4946045.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            89674..89994
                     /locus_tag="IXT46_000096"
     CDS             89674..89994
                     /locus_tag="IXT46_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HAQ4946046.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRR"
     gene            89999..90178
                     /locus_tag="IXT46_000097"
     CDS             89999..90178
                     /locus_tag="IXT46_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946047.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYRAKKASREGLTR"
     gene            complement(90298..90876)
                     /locus_tag="IXT46_000098"
     CDS             complement(90298..90876)
                     /locus_tag="IXT46_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946048.1"
                     /translation="MVVFSMNYILYVLLVVYTIIYIKQIVNAVSEITTINYLLTTIEK
                     VINDLKRLNDHSGSYKSDPYFQNNVTPIREIMVKEMPRINKVLPYSLVTLSLNQSDDI
                     LEENFRIIASQIFDKNNEIHYRKFWFLNPLIALKKFFLLPSEILSWFGINLSTFPGRI
                     FSLVIWVTSLFAQETISQILSFVITHFFKGQK"
     gene            90915..91613
                     /locus_tag="IXT46_000099"
     CDS             90915..91613
                     /locus_tag="IXT46_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAQ4946049.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKNTMRISGQQEFEIKQKGNMKVMEVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDENE"
     gene            91791..92132
                     /locus_tag="IXT46_000100"
     CDS             91791..92132
                     /locus_tag="IXT46_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946050.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELACDQ
                     DDLGNLVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGLGKK
                     YIAEMEAEFDE"
     gene            92125..92859
                     /locus_tag="IXT46_000101"
     CDS             92125..92859
                     /locus_tag="IXT46_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAQ4946051.1"
                     /translation="MSEGTKRSDNKLFNSLYKITVNDVVEKRNKLTYLSWAWAWAEVS
                     KICEEVDYEIYRDPETHRPYLFDEKTGYMVFTSITVNGVKRDMWLPVMDGANKAMKDE
                     PYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLGLYIF
                     AGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITADDSKW
                     TKRDLGILKRGVNWLEDQYREETKEK"
     gene            92865..93551
                     /locus_tag="IXT46_000102"
     CDS             92865..93551
                     /locus_tag="IXT46_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946052.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLNIGG"
     gene            93570..94385
                     /locus_tag="IXT46_000103"
     CDS             93570..94385
                     /locus_tag="IXT46_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer"
                     /protein_id="HAQ4946053.1"
                     /translation="MSDKQKKRYYWLKLKEDFFEEDTIEWLEEQPNGKEYCLFYLKLC
                     LKSLKTEGILVRNVGNLMIPYDPESLAKLTNSNTDTVKVAMDLFNKIGLIKILDSGEI
                     YLNQLSELVGSETEYARQKRIQRAKEDNVQKLSGKGRLEIELEKDIDIDIDKEEKKGK
                     HSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYVINWLP
                     TNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI"
     gene            94402..95253
                     /locus_tag="IXT46_000104"
     CDS             94402..95253
                     /locus_tag="IXT46_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4946054.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDLQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSYVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            95250..95609
                     /locus_tag="IXT46_000105"
     CDS             95250..95609
                     /locus_tag="IXT46_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAQ4946055.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            95624..95785
                     /locus_tag="IXT46_000106"
     CDS             95624..95785
                     /locus_tag="IXT46_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAQ4946056.1"
                     /translation="MTTEEVIQMRIRSIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            95782..96087
                     /locus_tag="IXT46_000107"
     CDS             95782..96087
                     /locus_tag="IXT46_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946057.1"
                     /translation="MIVDKKSAMKRIIKLTHSENWQEDKEIVAEVQKLGKSMWNEKPK
                     RRTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYMEEK"
     gene            96087..96398
                     /locus_tag="IXT46_000108"
     CDS             96087..96398
                     /locus_tag="IXT46_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946058.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDV
                     K"
     gene            96395..96625
                     /locus_tag="IXT46_000109"
     CDS             96395..96625
                     /locus_tag="IXT46_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946059.1"
                     /translation="MKYEIPLSEAGIQAIINGREVNLELPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSIDNTFRLGS"
     gene            96632..96835
                     /locus_tag="IXT46_000110"
     CDS             96632..96835
                     /locus_tag="IXT46_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HAQ4946060.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASDAIRKFGISILSDDRKWEEKE"
     gene            96832..97128
                     /locus_tag="IXT46_000111"
     CDS             96832..97128
                     /locus_tag="IXT46_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946061.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWTAKSKENLAVVRLVDMELINDK"
     gene            97205..97621
                     /locus_tag="IXT46_000112"
     CDS             97205..97621
                     /locus_tag="IXT46_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAQ4946062.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDALIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            98772..99116
                     /locus_tag="IXT46_000113"
     CDS             98772..99116
                     /locus_tag="IXT46_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAQ4946063.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            99121..99402
                     /locus_tag="IXT46_000114"
     CDS             99121..99402
                     /locus_tag="IXT46_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946064.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            99505..99819
                     /locus_tag="IXT46_000115"
     CDS             99505..99819
                     /locus_tag="IXT46_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HAQ4946065.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            99797..101491
                     /locus_tag="IXT46_000116"
     CDS             99797..101491
                     /locus_tag="IXT46_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAQ4946066.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            101511..102689
                     /locus_tag="IXT46_000117"
     CDS             101511..102689
                     /locus_tag="IXT46_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAQ4946067.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            102652..103338
                     /locus_tag="IXT46_000118"
     CDS             102652..103338
                     /locus_tag="IXT46_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAQ4946068.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            103338..104498
                     /locus_tag="IXT46_000119"
     CDS             103338..104498
                     /locus_tag="IXT46_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAQ4946069.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            104508..105383
                     /locus_tag="IXT46_000120"
     CDS             104508..105383
                     /locus_tag="IXT46_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946070.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSNVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            105380..105691
                     /locus_tag="IXT46_000121"
     CDS             105380..105691
                     /locus_tag="IXT46_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946071.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            105681..106034
                     /locus_tag="IXT46_000122"
     CDS             105681..106034
                     /locus_tag="IXT46_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAQ4946072.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            106024..106425
                     /locus_tag="IXT46_000123"
     CDS             106024..106425
                     /locus_tag="IXT46_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946073.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            106418..106822
                     /locus_tag="IXT46_000124"
     CDS             106418..106822
                     /locus_tag="IXT46_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946074.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            106834..107442
                     /locus_tag="IXT46_000125"
     CDS             106834..107442
                     /locus_tag="IXT46_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4946075.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            107462..107824
                     /locus_tag="IXT46_000126"
     CDS             107462..107824
                     /locus_tag="IXT46_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946076.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMSM
                     GKGSMDITVIQGAKAVYVAYRQANMVDYISFDEFIDKWDFDMEVAVAVYSTMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            107827..108009
                     /locus_tag="IXT46_000127"
     CDS             107827..108009
                     /locus_tag="IXT46_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946077.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            108027..111359
                     /locus_tag="IXT46_000128"
     CDS             108027..111359
                     /locus_tag="IXT46_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4946078.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNDIDKTSKALAQSKGEFKTYESTMKDLDNEQQHLKSSASLVESEYKKWQ
                     ATAGQSATESEKLAKAQEYVGKQSDIAEQKIEVLKKQLDATQKEFGETSTEALEMKTK
                     LNDAEREFEELSNAAKNVDTSTVDDIGKKLDMGNLMEATDHLSVIGDKLIDVGSKSIE
                     AAGKAQAMQAQFKQVFGSLEGEAQDAVEGMAEEFGMLPNTIKPVFTQYTSMFKGLGYD
                     TKEAMELAGDSTQLAADAAAFYDKSMDDASESLNSFIKGNYEGGEQIGLFANDTQMAA
                     YAVKHNLIPATEGAKKASEESLLAVEKAQSKYADAIKKHGEGSLEAREAALKLKDAQD
                     KINEELGPQTQKWSDLDEATKQAVRVQYAEDMQKLAGATGQASRESDGLENQMTRAKQ
                     ALEDFYASLGEDILPVFIKGLQAGAKALQGLAEWWSKLDGPMKNFILALGGILALLST
                     LAPVITAVVTIVGTFGSTVLLPIIGIIAGVAAVIAIVITAFQNWGAITDWFSDLWKKF
                     TDWLGDTWESIKESASSVWDGVKETWSGFVDWVQEIWQGVSDWFGELWSGLVEGASNI
                     WQGVQETWQAFVDWVSNIWNGVKEVWSIIWADIVGIVQIPWTLITSLIQAGINIIVGI
                     FDVAGQLLGAAWQAVWTPISDFLKNTWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNG
                     IWTSISTTASNIWNSISATASSIWNSIKNTITSLVQAAATVIQNIWSTVSSWLGGIWN
                     SISSTASNIWNSVTSSISNAINAAKSAIQSVWNSISSWISGIWNGIKNTALNLWNGIT
                     STISSKVNDGKNAISSGWSNLTGIVSDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKI
                     SGIFDNLNISIPHIPLPEFIMEGSFNPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGV
                     GEAGPEAVLPLKRSVLQEIGDRILSSTSVSSRAQTIQPVNNYEFNFTIDGNADEVTMK
                     QTTQQIIDSITKIQNDNASAWR"
     gene            111410..112147
                     /locus_tag="IXT46_000129"
     CDS             111410..112147
                     /locus_tag="IXT46_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4946079.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            112157..114448
                     /locus_tag="IXT46_000130"
     CDS             112157..114448
                     /locus_tag="IXT46_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946080.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            114472..116592
                     /locus_tag="IXT46_000131"
     CDS             114472..116592
                     /locus_tag="IXT46_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946081.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDDK
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISELGNLQVMYSNSINFGNYDYSGNPNLMINIKLEDLS
                     SELTGYRKPTNVTMENGCFVIDVTKLTGSQGYYILDVPRGLEGKRYTYSVEAKADVAT
                     QGIAIRPVYHNGTALAVLTPSSVGSLTTTMTRYKLTTNPLTAQQVNSTIQAFQIYIVP
                     SRCTAKKIYVKTNIKMEEGIEASGFQPNLLDAPYYFSKVALGENLIKPESQQPVTNSN
                     YLINTYNIKPMVKGKKYTITLEGTKPATQVFRPFFTRATGDAWEVGDLQPVEGLTDVW
                     SGTFTAAADPHPTSPQVQICQVPSTSLGNCTIKWLKLEEGDTRTPNIEQYKYLGIGMR
                     DSNNPKDYVWDLAPEYVEDNLATDVKISEITGKANNYTDGKVSEINSQLTASINEVDT
                     TAKDAQTKANANATAIKSTNSRVDEIENIITALTKEETYLLPASIVNGGSLKFTSRGG
                     MTVATGSFKLAKDIAFGEVLVNDLPDSMINIDNNAIGTGAVTGNSVSQIYVESNTRKV
                     VANTAMKKDQWFTVGFSYHSKLSI"
     gene            116649..116891
                     /locus_tag="IXT46_000132"
     CDS             116649..116891
                     /locus_tag="IXT46_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAQ4946082.1"
                     /translation="MKDEAIQDVVERLVRIETKLDNYESLREKADSAKDLADKAYSVA
                     LNNAEDIKEMKNNNKWAWGYMIGLGITIIGYFLTKL"
     gene            116907..117104
                     /locus_tag="IXT46_000133"
     CDS             116907..117104
                     /locus_tag="IXT46_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAQ4946083.1"
                     /translation="MILPDKYYQVIKWTVLTVLPATSVLVATLGKAYGWNGTDMTVLT
                     INAAATFLGVITGVSAYNLKK"
     gene            117115..118131
                     /locus_tag="IXT46_000134"
     CDS             117115..118131
                     /locus_tag="IXT46_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4946084.1"
                     /translation="MKKKIILSLSLIMALFLLPINGFAYTINNEFNLGANEGSSQVAN
                     NQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSY
                     ANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLW
                     VTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAANP
                     TLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYR
                     PDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLN
                     IPKR"
BASE COUNT        39458 a        19657 c        24823 g        34216 t
ORIGIN      
        1 ctctgagtca caaggaacaa tttcaaaaaa cagcttttca tgtttgatga atattgtgac
       61 ttgtgaccga ggagttggta ggagaacacc gtttaccaag aggttgtgaa aaagctgttc
      121 tgcatcaagt aataagaaga gccaagtaaa aacagtctct tatgttttta acttggctgg
      181 acttatcacc gtagatgtaa gcttttgaac gccgtttatt tgcaacaaaa ggggctgtga
      241 cacgattttt gtcacagccc tttttttgcg aacattcatt tagcaatttt tagaaacttc
      301 tgccgccacc gccaaaagtc ccgccaccgc tagaatgggt agtacttccg ccaccgccgc
      361 ttccaggagg tgggcttttg gggattcttc ttgtcgtgac aaaagaattt gtcagacgat
      421 cggttttttc agttaatttg atactggatt tttctcggaa tggatatttg tagatgcctg
      481 atttcaattg ataacgcgaa acagtcacaa aataaaagac aagactaagg ataagagcca
      541 aaacaacagc aatgatgatt tctactgtcg tcaaaacctt atagcgtgta attttgccag
      601 tttcttcgtc tacacgataa tgtcctcctg gaactccgtc ttccacatat gttgctgatt
      661 tagacaggta agcttttgca gcattgtaat aggcagcatt tgtcatctga tcataaacat
      721 catctaagat cgaatcgatt ctgctatcag tcaaataatc gatcatatta ccagaagtcg
      781 aaatgtagat ttcacgctgt cccatatcta atagcaatac tgagccattt tgatcatttc
      841 cgactgcgtc tcttaagtaa ttatcagcaa agtctcttgg ttcttctgaa ttagatgtag
      901 tcgttacgat caagactcgt cctttgattt tttcattcag cttttctgcc tgttgttcca
      961 aagattggat ttgatctgtt gtgaataacc cagcctcatc atttaccgta gctgtatctg
     1021 catgagtagc caccggccag ccaacactta ctagcaaaag aaagaataaa aaaaattttt
     1081 tcatcatatc aagtaacctc cgatcagaaa gaggatcgct agcccagcga aaatcccaag
     1141 agcggtcagt cccaattttt tctggctgat cggcaggaca ccgctgacct ttcctgtttg
     1201 tccattcatt gcgtagtagt agactttttt acttgagtca ttgcttcgat aagtaacaag
     1261 ccataccggc agtaatacgt aattatttac ttcgtttgtg attgaagcag aagttcgcac
     1321 accggtcaat gttgtatatc catttgcggt atcttttaac agcttctctg aatagtcttt
     1381 taattcagat tgaatctgtg atttgattgc ctcatattcg atatctcttt tttctgcttg
     1441 gaacccggct aaatactggc ttttaaaatc aattgcttta tctaacggga aaggttgcac
     1501 gccttcgacc atcttttgtt gcgtattttt tgataaggca ttttttacta gttctttaaa
     1561 agaaagcttg cctgctcttg aaacagcaaa ttgcttcgtt tctgtgtatt cgatgtcacc
     1621 tatccgccat atgcggataa ctgtaccatt cgcctgcatg gcaccatcta cttcagcatc
     1681 tgtagcccaa taagggaaat acacacctgt caacttatcg atttgatcct tattgaaaaa
     1741 agctttggga acaaaccatt ttttcttggt ccaagcgaga aatctgttga ttgcttcttc
     1801 tttctcgaca gcaaaaggaa gtactttatt tggcaagaat tctccgctta aacgtcccga
     1861 tagtacgacg ggattatggc agtagtaaca ataagtcgca gcagttgtcg catcagtcac
     1921 gatctctgca ccacagttgg gacaaagaaa aagatctatc gctgcggtat tatctgcaga
     1981 ttcgtccgct gtatctgaaa aaccgcctgc ctcgtcaacc gctttgcgct cggcttcatt
     2041 catatcggca agctgttctt gggctgtaaa agtaaaatct tcggtaggtg aaggttcttc
     2101 tttgctttct tcgccagcca tacgcgcttc tttttgcttt tgctcatatt ggctgacttc
     2161 ttcttctgta tagatattca ggcagtattc gcaatgaaat ttttggtctt tgggatcaaa
     2221 agtcaacgga ccgccgcaat taggacattt atgtgtaaga acatccatca gctgcacacc
     2281 tttctaaata aattaattaa cggggattcc tttaaacggt ttaccacagt ttggacagaa
     2341 tttagggatg ccgttggaaa gatccacgat ctcattgcat tcactgcatc gcatttgtag
     2401 cttaggctga acgttttcta caggtttggc agctccgcag ttggaacaga attttccgga
     2461 attttctgtc ccgcaaactg gacatgtcca agtatccgca tttccttgtg cagtttgttg
     2521 attttgtttt tctgcttgtt gtttgatttg ttcttggtta ttttgagctg cttgagaaag
     2581 ataagaacca tttgcattca ttcccatacc tacacccata aagccggtca ttgctcctgc
     2641 ttcatttttt ccggctgctt ccataccacg tgcaatggaa ccttgcacgt atccttcacg
     2701 tacgctagga tcacctagca tcgccccttc gttacgcata ttgatcagtt tcacagaatc
     2761 atcggtgtaa gaaatgctgg ctacagccac agaaacaatc tccatcccac gtaattcacg
     2821 ccaagaatca tccaatgcag tatccatgta tttgcttaat tccaaactct tagatggtac
     2881 ataagaaatc cgttgaccat ctgcagacat ctgattgatt gctgattgta gcgctgttag
     2941 gaattcagct aaatactgct cattgatatc attgatttcc acttgtgttt tgtttttagg
     3001 gattgcgttt gtataaaata aaatcgggtc aacgacatga atagaataag tgccatgtgc
     3061 ccgtaagaat aattctgcgt tatagaaatt gtcaaagtag ttcaacggcg cgcttgtacc
     3121 gaatttgatt ccctttattt cttggagatt gatataaaaa acttgttgtt tctgcggtgt
     3181 gacgccgcca aatttgaatc ggtcaaaagt ttcagcaatt gcttctttca gtgttccatt
     3241 gaacatggaa ggagctgcgt catttttaat ggtgtaataa ccttcctcag cggtataatc
     3301 gatgattttt ccaccatcga ccaaaagcat catcatgttt ggatagacat ggacgactgt
     3361 tccgtctgtt aaaacatctt ctgttccttt acgattggag ccacgtttgt catctttgcg
     3421 gactttgaca ccttttgtca tgaccgttgt atcactcata ttgtctggtt cgatgacttc
     3481 tagccattga tctgccagac cgccgccaac catacttgtt gctgctttga taagacccat
     3541 aaaaaattcc tcctctgatt cagctagtgc caaacaatta ttgtttattt attataccat
     3601 aggaagatgt gaaacttctc ggactagaga cggaattgaa atggaaaatt gcgtattgtt
     3661 taaatacctg aaaaagccga gaaggatagt agttttttta cctaatatca cgtataataa
     3721 gagatagtga attttttaaa aaagggggat ccttatggca tatcaagcac tttatcgagt
     3781 ctggcgttcg cagcgtttcg aagacatcgt tggacaaaaa gctgtgacac agacactaaa
     3841 aaatgctatt gtttcccaca aaacctcaca tgcctacttg tttacaggac ccagaggaac
     3901 cggaaagacg agtgcagcaa agattttcgc aaaagcaatc aactgtccga acagtaaaga
     3961 cggtgagcca tgcaacgaat gcgaaatgtg tcgatcaatt actgctggta cgcaagaaga
     4021 tgtgatcgaa atcgatgctg ccagcaataa cggagtcgaa gaaatccgat ttatccgtga
     4081 tcgggcaaat tatgcgccta caaaggcagc gtacaaagtg tacattattg atgaggtaca
     4141 tatgctttca acaggagctt tcaatgcctt gttgaaaaca ttggaagagc caaaagaaag
     4201 tgtcatattc atcttagcaa cgaccgaacc tcacaaaata ccagctacga tcatttcacg
     4261 gactcagcga tttgatttta aacggatcaa tacggcagat attgtcgaac atcttgaatt
     4321 tatcttgaaa gaatcgacta tcagctatga accagctgca ttgaatgtga ttgcccgttc
     4381 tgcagaaggc gggatgcggg atgcattgag tattcttgat caggcaatct cgtttagtga
     4441 aggaacaatt actttagatg atgccatgca agtgacaggt agcttaactg acgaaatgat
     4501 ggacagttac ttgagtgctt gcgtgaaaaa agaagtacca gaagcattgg aaacattgaa
     4561 ccaaattctc gcagccggca aagaatcacg tcgctttcta gaggatatgt tacaatactg
     4621 ccgtgacttg ctgatgtatc agcaagcacc taacctagtt gaggaacaat cgagtacgat
     4681 cagaagtaca tttacagaat tggcacaaac tgtttcagcg gatcagctgt tttcaatgat
     4741 aaagattttg agcgatactc aaaatgaaat tcgttttacc aatagtgccg ctatttattt
     4801 ggaagtcgct acagtcaaac ttgcacagct accgtctgct tctgttcctt cagcagatgt
     4861 agcatttgca gatgatcaga tagtaaaaca gctacaacaa gagattaagg aactaagaaa
     4921 cgaaatcaag gaactacgca gtaatacagg aattgagaat acaaaagtac agccggtaca
     4981 gcaaacaaat cataaaaaac agacaagtac ctatcgtgta ccgacggaac gagtatataa
     5041 agttctgcgg gaagcgacaa gacagcatct gaaccaagta aaagaagtat gggaagactt
     5101 gctgatgagt ctatctgtca ctcagcgagc aatgcttaaa gcaagcgaac cagttgcagc
     5161 tggacctaca ggactagtga ttgcgtttga ttatgagatt gtttgtcaaa gagcagcaaa
     5221 tgacgaagaa ttgcagcttt cggtacacaa caacttaagc cgaatgatca aagattatgc
     5281 gcctgatcct gtttatatta caagagaaag ctggccagaa cttcgaagaa attatttgac
     5341 gcaggcacaa gaagagggaa cagaaaactc ttttgcttct gaagactcag aaggagaaat
     5401 cgagttgctt cctcaagaac aagaagtacc agaagaaaca cttgtagtaa aagcagagga
     5461 actgtttggc tccgaagctg ttacagtggt agatgattaa taaaaaggag tagataatta
     5521 tgatgcgtgg aatgggcaat atgcaaggca tgatgaaaca agtacaaaaa atgcaaaaag
     5581 aaatggcaga agcacaagag ctgctaaata aaacagagtt tacaggtaaa gccaccaatg
     5641 aattggtcaa agcggttttt acaggcgatc gtcgcatgaa agatatccaa atcaatgaag
     5701 aagtcgttga tcctgatgat atcgagatgc ttcaggatct tgtcgtaatg gcagtcaatg
     5761 atgcgatcgc acaaattgat gtggaaactg agaaaaaatt agggaaatac gcaaaaggtt
     5821 tgccaggatt ttagttttaa actgaaggag taatgaatat gcaatatcca gaaccaattg
     5881 cgaaactgat cgacagctac atgaaacttc caggaatcgg tcagaaaaca gcgacaagac
     5941 tcgcctttta tacgatcgat atgaaagatg aagtagtaaa tgaatttgct aaatctttgt
     6001 taagtgtaaa acgcgatttg catttttgta gtatctgcgg aaacatcaca gaagaagatc
     6061 cctgcgaaat atgtagaaat ccttcacgtg atcgaagcgt tatcctagtg gtcgaagagc
     6121 cgaaagatgt aatggcaatg gaaaaaatgc gagaatatca cggactttat catgttctcc
     6181 atggtgtgtt atcaccgatg gaagggacag gtccagaaga catcaatatt tcttctctgt
     6241 tgcagcggct gcatgatgca gatgtaaaag aagtgattat cgcaacaaat gcaacaacag
     6301 agggagaagc aacagctatg tatctctcac gtctgatcaa acccgcaggt atcaaagtga
     6361 ctcgtctagc acatggtctg tctgtaggct ctgatatcga gtatgcagat gaagttactt
     6421 tattgaaagc tgtcgaagga agacgtgagt tataaatttc taattaagtg ttttttcaga
     6481 tacaatataa aagcagcaca agagatgggg gcaacaatgt gaacggacta tttattacaa
     6541 tcgaggggcc tgatggtgca ggaaaaacca gcatcttgaa tgaactttac cctcttttga
     6601 aagaagtagc aaaaacagaa atcattcaaa caagagaacc aggaggcatt ccgattgctg
     6661 aagagatccg agcagtgatc cttgatccaa aaaatgatcg gatggatgaa cgtacggaag
     6721 cactgcttta tgcagcagca agaagacaac atctagtcga aaaggttctg cctgctctgg
     6781 caaaagggaa aatcgtttta tgcgatagat ttgtcgacag ttctcttgct tatcaaggtg
     6841 caggccgacg catcggcgtt accgagattg ctcggttgaa tgagtttgct acagaaggta
     6901 ctacgccgga ttttaccctt tatcttgacg tagattcaga caccggatta agaagaatca
     6961 agaaaaacag acaaaatcaa atcgaccgtt tagattcgga aggtttggaa ttccaccagc
     7021 gtgtacgtca tgcttactta aagctggcag aagagaatcc ggaaagaatc cacaaagttg
     7081 atgcaagaaa aagctttgaa gaagtgctgc aaacaagtta tcatacaatt attgaacagt
     7141 atccgcaatt ttttgaaaac taggaaggtg aacgtttatg aaaattattt tagcgattat
     7201 ccaagacaaa gacagcaacc gtttatcaaa tgaattgatt gatgcaaata tccgtgccac
     7261 aaaactatca tcgacaggcg gcttccttaa ggctggaaac agtacgttta tcgtgggtat
     7321 tgaagatgac cgtgtagaag aagcattgga aatcatcaaa aaaacgtgtg aatcaagaaa
     7381 gcaatttgta tctacacctg ttacactgga tatttcgatg gatgggggcg tcccttatcc
     7441 agtagaagta gaagtaggcg gtgccacagt cttcgtctta cctgttgaag gattccatca
     7501 attttaggag gagctgagct atgaatcaag aaataaactt ggctcaaatg caaccgatcg
     7561 tgtatcagca gcttcaacgg agttttgagc atgggcgtat cgctcatgct tatctttttg
     7621 aaggggagaa aggaacagga aaacatgaag taggtatatg gcttgcacag cacctgttct
     7681 gtacccaaat gaaagacaat ctgccttgtg gaaaatgcaa caattgtcag cggatcgaaa
     7741 agaaagaaca tccagatgtt ttggttattg aaccggaagg acaaaccatc aaagtcgatc
     7801 agatcagacg tttgcagacg gaattcagtc gcagcggtta cgaatcaaga aaaaaagttt
     7861 ttttgatcaa agaagctgaa aaaatgaata gcagtgcggc aaacagtttg ttgaaattct
     7921 tggaagagcc ccctggagat tttttagcgg tgttagaaac agatgcagta ggaagaattc
     7981 tccctactat tcaatctcgt tgtcaagttc tgcattttca agaactttcg aaagaagcac
     8041 tgatccatcg attgcaagaa gagcagattc cattggaaaa agcaaaactt ttggctttct
     8101 taacaaacag tttaggaaaa gcagttgaaa tctctcaaga tgaatggttt aatgatgcta
     8161 aggacttgat ttatcaatgg ttcgtttact tgcaaaagca agatactcaa gcctttatct
     8221 atgtccaaaa aaaattggta aaatcattta aagaaaaaac acaacagttt acaggattat
     8281 ctgtcttgat gttttattat caggaagcac agcgtcaagc agtagcaaac ggcgaatatg
     8341 gcaaagtgaa acagataaac cagataattg aacggatatt gatcgcagag cagaaactac
     8401 gcagcaatgt cagttttcag gctgttgcgg aacagttcgt tttgcatacg attttttagc
     8461 ttgccgcaaa ggatgatgat caaggaggat ggaaatggta gaagtagtag gtgtccgata
     8521 tagagatgca ggtcatatct attattttgc accaggagac tctgaatatg tttatagtga
     8581 caaggtatta gtcgaatctc agcaatcctt acatattgct actgttgtcc ttcctaaaaa
     8641 agagattgat cccaatgacc ttcctgaagc tatccgtccg atcttgcata aagcgtcaca
     8701 agctgaatta gaaaaagaca aaaaaaacaa aaaagatgct tatgatgcat tgaaaatcgc
     8761 aaaagaaaaa gtgcagttgc gtgagttgga aatgaaaatg gtcaaagccg aatacacatt
     8821 tgatcgaaat aaattgattt tttctttcac agcggacggg cgaattgact ttagagaatt
     8881 ggtaaaagat ctggccgctg tatttcgtac tcgtattgag cttcgacaaa ttggtgtccg
     8941 cgatgaagca aagataatag gcggaattgg tccatgtggg cgtccattat gctgttcttc
     9001 ttttttaggc gatttcgtgc ctgtatcaat caaaatggca aaagatcaaa gtttatcttt
     9061 gaatccaaca aaaatttccg gtttatgcgg acgcttgatg tgctgtctgc aatatgagag
     9121 cgaagaatac gagacagcga aaaaagaact ccctgacttt ggaaaagtaa ttgctacacc
     9181 tgatggtaaa gggaaagtcg tagggttgaa tctgcttagc cgtatcgtta gtattcggct
     9241 gactggacgg gaaaatcctg tcgaatatga atgggatgaa ttgaaagaat ttatccaagt
     9301 aggtgagatg aatggataag agatcattat acgacggatt gaatcaatta gaatcagagt
     9361 tgagaaatac attaacagaa cttgttgaaa tgaagcatgc tttgcatgag atcgtagaaa
     9421 aaaatacaac tttggagatg gaaaatcaac gtctgcggga acacctgcgg gaattgaacc
     9481 aagttgcaca agctccagct gaaaatgtga agcaggaact ttctaagtct cgtatgaatc
     9541 ttgaaaaaat ttatgaagaa ggattccatg tctgctacga tttatatgga tcaagaaggg
     9601 acaatgacga gccttgtgcg ttttgtctag aagtgatcta tcgcgaaagc ggtcgatgac
     9661 caataacaag aggagactgg agcggagaaa tactgctcca gtctttttat taaggagatt
     9721 gtgacagatg tataatcaaa aaagtttcaa gggaaatccg gtatatgggg atttatatct
     9781 tgtaccgacg ccaattggaa atttagaaga tatgagctac agaagtgttc gtatgctgca
     9841 agaatccgat cttatcgcaa gtgaggatac gcgtaataca caaaagttat tgaatcattt
     9901 tgaaatccat acaccccaaa aaagtttaca tgaacataat tataaagaac gtgtccctca
     9961 attgattgct ttgttaaaag aaggaaaaac gattgctcaa gtcagtgacg caggaatgcc
    10021 ttccatcagc gatcctggac atgagctagt tttagcctgc ataaaagaag ggatttctgt
    10081 gatctctatc ccaggaccta cagctgggat gacggctttg attgcttcag ggctagtgcc
    10141 tcaaccattt ttattttatg gcttccttcc acgtaagaaa aaagaacaga aagaaacatt
    10201 gaaaaagcta aaagaacaga cagttacgct gattttttat gagtcacctt atcggatcac
    10261 tgctacattg acgaatttct tagaaatttt tggaaatcgc caagtcgttt tgtgtcggga
    10321 attgacaaag gtccatgaag aataccttag aggaagtacg gaagagctac tcgcttatat
    10381 cgaagaacat ccagtaaagg gtgaatgttg tctgcttgta gaagggaatt tgttcgaaat
    10441 gccagtgacg gaagttgatg aagagttggg aacgttaaag gaacaagtag aagcaaagat
    10501 cgcttcaggc gaaaaaccaa atgctgctat caaagcagta gcgctgaaaa atgggctgaa
    10561 aaaacaagaa gtctaccgtc agtaccatga attagactga gatagtataa gttgtctata
    10621 atgaaagact aatgaggaaa tcagctacta acttttcaaa tctcttgaac gcgaacgaat
    10681 gttcttgtat aatgaataag aggtgaggat gatggagctg caatttcctt tacataatga
    10741 tacatcaaga aaaatcattc atattgatat ggatgctttt ttcgcttcgg ttgaagaacg
    10801 agatcatcct gagtttcgcg gacatccatt agtaattgcc agacacccca gtgacactgg
    10861 tgggcgtgga gtagtgacta cagcaaatta tgaagcaaga aaattcggaa ttcattcagc
    10921 aatgagtgca caaaaagcgt atgagctttg tccgcaagcc atctttaagc ctggcgacca
    10981 tcataaatac agcgatattt ccaaacaagt acgggaagta ttctatcgtt atacagatat
    11041 tgtggaacca gttagtatcg atgaagcgta tcttgatgtg accgaaaata aaatcaattg
    11101 caagtcagcc atcaaaatcg cccgaatgat ccaagcagat atttgggaga gtgtccagct
    11161 aacatgttct gcgggagtaa gttacaataa gtttttggcc aaattagcat cagactatca
    11221 aaaacctaga ggaatcacgg tagttgcccc tcaagacgct gtgccatttt taaaagcttt
    11281 gccaattgaa aaatttcatg gggtagggaa gaaaactgta cctagaatgc atgagctagg
    11341 gatttataca ggaaaagacc tatatgaatg cacagaaatg atgttgattc gaaattttgg
    11401 aaaaatgggc tattctcttt atcgtaaagt cagaggaatc catgattctc cagtaaacgt
    11461 tacaagagag cgaaaatctg tgggaaaaga gcatacttat gggcagccgt tgcaaacgga
    11521 agaagcagtg ctgactcagt tgcgccaact agctgaaaaa gtagaagaag cactgagaag
    11581 agtccaaaaa catgggaaaa cagtagtttt gaaggtcagg tacacggact attctactgt
    11641 gaccaaaaga gtgacattgc cagaatatat ctataaaaaa gaagcactct tttatcaagc
    11701 aagccttata tgggaggaaa tcttgggagt agaaaaagga atccgattgt tagggattac
    11761 tttgacgaat ctggacccga tgacttatga aaacatcgtc cttccattat gggaaaatca
    11821 agaaatataa aaacagcttt gagagttgaa accggaaatc cgttttctct cccaaagctg
    11881 tttttatatc aagtcttgct ttttgatttg ttcataggtt tctgttgcat ccgtacattt
    11941 ttcccaaatc acaacttgat tggattctaa agatttttgg acgtcaatga tccgctggtt
    12001 gctacttccg cgaaattgta gttttaggtc acgtttgctt aattcaaagc gtccgtcaac
    12061 aaggatatcg atttgcgaaa ggagttctaa tttatcttct gaatcttgta gcaattcatc
    12121 aaaggtatag cctgtccatg accagatatc ttttgtcgta ccgaactctt ttcggatacg
    12181 tcgtacgact tgcagacaaa catctgtatt caaaaaaggt tcgccaccaa gtaaagttaa
    12241 tccttgcacg taatcgttgc gcaagtcagc gatgatttgt tcttctaatt caggtgtgaa
    12301 tggtttgcca tatcggaaat tttgtgcagc tttgttgaag cagccttcgc aggcaaataa
    12361 gcagccacta acgtaaagac tgttgcggac accttcacca tcgacaaaat taaacggttt
    12421 gtagtcagca atatagtttt ggctgtagtc ttttgctaac cattcttttg gttttggatt
    12481 tctcataaaa aaacttcttt catttaaggt tcaaagatat agctattgaa gataaaatct
    12541 actcgaccac ataaataaga acaaactgac ctaaatccat tgttcaagaa agcttgttct
    12601 tattttgata gagggcgttc aaagatacaa agccatcgaa agagggtggt gaaaaaagac
    12661 ttgtcatagc ctcttattct gaataaacgg tgttcaaaag cttgcatctg cagtaataag
    12721 cccaactaaa cgaaaaatat gaggaactat ttttgtttag ctattcttat tacttgatgc
    12781 aggacagctt tttcacaacc tcatttcatg tgtttcacac gtgaggaaat ttctttatgg
    12841 cggccatgta ccatcggacg agcttgcgga tttcctaaat agccacaagt acgtttgact
    12901 acatcacatg tttttggatc atgatttcca cattctggac attcgaaccc tcgttctgtc
    12961 ggtttgaaat caccttcgaa accacattga tagcaatgat cgattggcgt attcgtacca
    13021 agatacccga ttttgtcata tgcaaaatcc catacagctt ctaaagcttt cggattttgt
    13081 tggagcatag ggtattcaca gtagtggatg aatccacctg aacaatattt tggataatcc
    13141 ttctcaaatt ccaatttttc aaatggcgtt gggtttttac gcacatcata gtggaaactg
    13201 tttgtataat attctttatc tgtgatattt tcgatgatgc cgaatttttc tgtatccaaa
    13261 cggcagaaac ggtcagttag actttcactt ggagttgaat agacactgaa atgataacca
    13321 tattcatccc cccatgcatc tgcattagct tttaattctt tgacgatatc aagtgtgaaa
    13381 gcttttgctt ctgggtttgt ttcccattcg ccaccgaaga aagctgaagc aacttcatac
    13441 aatccaatgt agcctaacga tacagtagct cgacggtttt tgaataattc attgacagaa
    13501 tcggtacgtg aaagacgttt cccgaaagca ccatacatat ataaaattgg cgcatttgct
    13561 ggaatggctt ctttacaacg ttctacacga tagagaagcg catctttcat gatttctaag
    13621 cggtcagaca gtaactgcca gaatttattc tgatctcctt ttgattcgat cgcgattctt
    13681 ggcaaattca atgtaacaac acctaaattc attcgtccga catttacttc ttgaccattt
    13741 tcgtctttcc acccttgcaa gaatgaacga cagcccatag gtactttgaa acttccagtt
    13801 aattcaacga ttttatcgta attcagaata tcaggataca ttcttttcgt tgcacattcc
    13861 aatgctagtt gtttgatgtc gtaattagga tcttcagggt ttaagttcac accttttttc
    13921 aaagtgaaga tcagtttagg gaagatagct gtccgctttt cactccctaa tccattgatt
    13981 cgaatctgta aaattgcttt ttgaatttct ctttcaaacc agttttctcc tagtccaaat
    14041 cctaatgaag tgaaaggagt ttgtccattt gaagtaaata aggtattgat ttcatattcc
    14101 aaactttgca tagcatcgaa gatatctttt ttggtttttg cttttgcata ttctttttgg
    14161 cgttctggcg aatcgatcca ttcttccgcg tcttttagat gttttttata gttcaattct
    14221 gcaaaaggag caagcaattc atctgttcgg tcggcagaac agccaccata ttgacttgac
    14281 gctacattgg caataatctg tgagatttgt gctgtggcgg tctggataga ttttggcgat
    14341 tcgacttcgg cattgccgat tttgaaccca ttgttcagca tgcctttgaa atcaatcaag
    14401 cagcaattcg tcatcggtgt ataaggatga taatccaaat catggtaatg gatatcgcct
    14461 ttttgatgcg catttgctat atgtggtggc aacattttca gtccgattga ttttccaacg
    14521 atcccggctg tcagatctcg ctgtgtattg aaaacattac tgtctttatt tgcgttttcg
    14581 ttcacgacag tttggtcctt gttgattagc ttttcaatcg aaaagttgat atctgttgct
    14641 ttactgcgag caaaatctcg tttggtacga taattgatgt actcttctgc taattcatat
    14701 tcgttttttt ctagtaatat atgttccacg atgttttgaa tctcatagat tttgacattt
    14761 tcagcaaacc ggcttttgat ttcttggaca accaagtctg caatcatttg aattttttca
    14821 taagtaagtg gtgataatga gccgtgaatt ttcttttctg ctttgatcag tgcttcattg
    14881 atcttttgtt catcgaaatc aacatggcgg ccatcgcgtt tgatgacttt catctgggat
    14941 gtctctggct gctgagtaac gacagttttt tcttcataat ttactttcat tatcttcaac
    15001 tcctgctaaa ttgttcttgt ctatcataaa acaaaatcgg ggaaggagca actaaatatc
    15061 ggctatatat agtattcaat gtgctgtata attggatttc tatactatat gtagtgtata
    15121 ttttattgtg aaaaaaggtg aaaacttgta gctggtggat ttgttttttg catatttaat
    15181 tttgctgaat aaaataattg aataaaattt tttattcagt ccaagtaaaa gtgacaaaaa
    15241 cataagagca aattattcgt agatatgcta ctatgcaaat aaatagaaat gaaaaatgaa
    15301 agaggaggag aagaattgga aaagatgatc gaagtgaaac atctaagtaa aagctacggc
    15361 agcaaacttt ctcccgtcaa agccttagat aatatctcat tcacagtaga agaaggcgag
    15421 tttgttggga ttatgggccc aagtggtgca ggaaagacaa cgctgatgaa tatcttgtcc
    15481 acgatcaatt tgcctacgat gggcagtgtc tcgatccaag gaaaagaaat cacaaaaatg
    15541 aaaaacagtg agctcagtga ctttcgtcga aaaaaactag gattcatttt tcaagagttc
    15601 aatttgatcg ataccctaaa tgcaaaagac aatatcctat tgcccctagc agttgaacgg
    15661 atgactaaag aggaaatgga aaagagagta agacatgtag ctcaattgtt gaatatagaa
    15721 gaactgctca aacggtatcc cgatgaactt tctgtcggac agagacaacg aattgcagct
    15781 gctagagcac ttgttgttca gccacaagtg atttttgcag atgaaccaac tggctctttg
    15841 gactcgaagt cggctacaga attgttgaac tacttgaaga ccatgaatca aaaagaaaaa
    15901 gcaacgatac tgttagtcac ccatgatcca tatacagcaa gctactgcga tagaatttta
    15961 tttattaaag atggtgtgat tttttctgaa gttgtcagaa gagggacaag aagagagttc
    16021 tttgagaaag taatagacat gcaggcgacg attggcggag gaggaaaaat gaatgctgta
    16081 taaactagcc gttaaaagtt tttttcggca gtcacgaggc tatcttgttt attttttcag
    16141 tttgacttta tccgtaatga tctattattc cttcagcgca atgacctacg atcaatcttt
    16201 agtcagaaga gcaagtcaag atacttcgat agatggtgga ttgagttttg gtggatttat
    16261 cattactgtt gttttgcttt ttttcgtatt cagtgccaac cgatttttct tgaatagaag
    16321 gcaaaaggaa ataggcatct atcagctttt tggtatgaat aaactgcaga tatcaggtat
    16381 atatgtgtta gaaatcatga taattggatt gttcgcctgt atttctggga tattactcgg
    16441 tattattttt tccaaactct tttcaatgat tttggttcga atgatggata tggatcttac
    16501 tagtccattt tttatctcca ttccatcagt agtagatact ttatttgctt ttttcatcat
    16561 ccttttagca gtatctgtat attcaatatg gaaaatatgg cgctatccaa tgattcgaag
    16621 ttttggagaa aaagaacaag cagatagttc aacaatgcgc ttcaggacaa ggcaccgatt
    16681 actcgcagtc atcgggttac tacttttaac gagcggatat tttggagcta gtcattttag
    16741 ggaaatcact tcatggatga tcagttatca ttatcttgat acattagttt tcttttttcc
    16801 ttttttaatt tttttcgttt gtgtggtcgg tacttatttg tttttctgtt atacatttcg
    16861 gttatttttg atcatattga gtaaatggaa gatttattac tatggtatca attttttgat
    16921 aatgggtaac acgcaagttc atttgctcaa aagttggcgt acaaattctc tgattacagt
    16981 cattctcgga atttctttaa tgacaattgg cggcacggct agtatctcta ctattttatc
    17041 ctaccaggag aaagtttcct ccccgatgga ctatcagttt gatgttgaga cagagaaaaa
    17101 aatcaagccg attctagcag aggaagggca gaagataact aaagaaatca ccttgcatta
    17161 taaagtcatt gggagtatct atagtcaaaa tctcgaagaa cctatgtttc aaactgctaa
    17221 tctgatcacg gaaacacaat atcaagcctt cagaaaagtt aatccagatt tgccgaacat
    17281 ttctttgaaa tcacctggtc atactgtttt gcttgatcaa atgcaaactc tttttcggaa
    17341 tatttcatta tatggatcta gtattggact gccagataat caagaattga agattcaaca
    17401 aatgcttcca agtgtattag gtgacgaaac aatggtatat ctaagtcctg tactgattgt
    17461 agatgatacc gtttttgaaa aagcaaaagg tgtggattat caagtagtca atgtagatgt
    17521 atcaggtgga aataatgaaa aaatagatga acgactgagc aatgacctgt cgataaagtg
    17581 gctcaatgct gtttattatt cttatgatat cgtaaatgga agtctacaag gagaaattag
    17641 cacaaagaaa cttccggatg accaaatgaa ggaagcacaa tttagccaag aaagctctcg
    17701 tttgaatttc tcttccagct attcgaaatt gcgtgcagtt aatcggcgaa tcggtatcaa
    17761 tatttttgtc acactatttg tcgggatgat cgtgattatt gctactggta gtattttgac
    17821 agtccggcaa ttagcagaag cagaggaaga aaaagaaaat tatcacctat tgactaagct
    17881 ggggattcca caaagaagga tcagacggat gatcttcgag caaaacgcac ttaccttctt
    17941 tccacccatg atattaggga tcactcacgc agtatttgca atcaatgtct tcactcagta
    18001 tataaaaact gccgattact ggttggctta tcttgtgagt ggcttattga tccttatcta
    18061 tcttttgctt tatgtcatta cgagtcagtt atattgtcgg attatcgagg aatgatatac
    18121 ggaataagac aagataataa atagaactaa attttgaata ccatttattt ggaataagag
    18181 gttgtgacac gatttttgtc acaacctctt tattttttat attttttaaa agtacgagaa
    18241 attataaaga aaaaagcagt gatttgatgt gctattttta taaaagctat gtgacaaaac
    18301 tgttagtaaa aaaacggttt ctgtaagcta gacacatgtt tctttttgtc aaaattagtt
    18361 acactttgtg tgaggttata tgaggaggga atccaatgaa caaatggcgt tctaatccaa
    18421 aattgaatta ttggggaaaa ttcatcattc gaacaatttt ttatagtgca gtactgctgt
    18481 tcctgattta tctgtatcac tataaaaata ttcaaggagg aacttttatc tataacgaat
    18541 tttaggagga agagtatgga aatcaaaacg attattgaag caatcgatga ttggggaata
    18601 aatgaacctg atcgagttgc ttatcaggcg gatgagacgc atacttttgg tgaattgaaa
    18661 caagcatcag acgcacttgc ttattattta gaaaaaaagg tagaaggcga tggaccaatt
    18721 gtcgtttttg gcaatttgga gtttgaaatg attgtctcat ttctaggggt tgtcaaatct
    18781 ggccatgcct atttgccgat tgaagagcat acacccaagg agcgtatcct atcgatcttt
    18841 cgggtggcta aaccatctat ggtcatcagt atcggggact ggatagaaga tattccttcg
    18901 gttcctgtca taacaaaaaa agaatttcaa gaaatcaaga agataccagt aggattttat
    18961 cccagaaata gcgtaaaagg tacagaaaat ttttatatta tttttacttc tggtactact
    19021 ggagaaccaa aaggcgtaca aatcagtcat gataatctag tcagctttgt tcaatggacg
    19081 atggaagact ttgggatcaa gcctggtatg catttcttag cccaagcgcc attttctttt
    19141 gatttatcgg tattttctat ttatcctgca ttagtttctg gcggaatgct gaagccgtta
    19201 aataaagcag ttgttcaaga ctttcgtcaa ttattcgcga cattgccagc cttgaagttg
    19261 aatgtgtggg tttctactcc atcatttatg gatatttgct tgatggaacc tacattcaat
    19321 ggagaaaatg tgccggaatt ggacatgttt ttattttgcg gagaagaatt gacgaaaaaa
    19381 actgcagaaa gtctacttga tcgattccca aatgcacgga tatataatac ttacggtcca
    19441 acagaagcaa ctgtagctat ttcaagtatt cagattgacc agcatgtact agatagttat
    19501 gaccgactac cgattggcta cgtaaaaaaa gacacgaaag tttctattgt ccaagaaggt
    19561 aaacctgttt caaaaggaga aacgggtgaa atcattattg caggaccaag cgtatcaaaa
    19621 ggttacctga acaatcccga aaagacagct gctgcgttct tttgtcaaaa tgacttagca
    19681 agttaccata caggggatgc aggtagacta gatgaatatg ggcttttatt ttatgaagga
    19741 cgtatggatc agcaggtcaa attacatgga taccggattg aactcgggga tatcgaacat
    19801 tatctgctcc aagacaaccg aatcaaacaa gctgtcgtcg taccaaaata ccaaggaaca
    19861 aaagtacagc agctggttgc ttttgtcgta ttagaaaaca aaacgaaaca gccggatttt
    19921 cagttgacta aatctatcaa agaacaatta ctagaagttg taatggatta tatgattcct
    19981 cagaagttcc attatgtcga tctgctgcct cagacagtta atggaaaaat cgatcgaaaa
    20041 aaattaacag ctgaggtgaa tcctgaatga tgttacctca tatgatccct tatgcagagc
    20101 cgttttattt ttttctttta gccattgcgc ttgtaccgat cgttctatct ttattgatat
    20161 gggaaaaaag attaccagtt tatcaatcag cagtgacact tttcttttta tttgtcagct
    20221 ttggaggtaa ttattggcaa cagggagcgg cgctgattgg gtatgttttg tggcagacga
    20281 tacttgtatg gggctatttt gtttatcggc aaaggaaaaa tcagacagga tggttttttg
    20341 ccgccgttat tttagcgata attccactgt ttttaacgaa agtgactcct ttttttgaac
    20401 atggaaaagc atcgttactt ggttttttag gaatctctta tttaaccttt aaatctgtac
    20461 aaatgatcat ggaaataaga gatggcatga tcaaaacata taagccattt cgttatatcc
    20521 agtttctgct gttctttcca acaatctctt ctggaccaat cgatcgctat aggagatttg
    20581 aaaaagatca gctccatccg cctgttcgtg ataaatatgt tgatcttttg ggaaaaggcg
    20641 tccaaaatat ttttgtcggt tttttatata aattcattat cggttattat tttggtcaag
    20701 tactgcttcc tgtagtggga cgcattgcct tacagcatgg tggtatttca tgggcattag
    20761 taggttatat gtacgtgtac agtatgtatt tgttttttga ttttgctggc tatagcttat
    20821 ttgcagtcgg tacaagctac atgatgggat atcagacacc aatcaatttc aataaacctt
    20881 ttttatcatg gaatatcaaa gaattctgga atcgttggca tatgacgctg tccttttggt
    20941 tccgtgatta tgtatatatg cgattgatgt tcttcatgat gaagaaaaaa ttttttaaaa
    21001 gcaagatcgt aatgtcaaat atcggttatt ttgctttgtt tcttctaatg ggtatatggc
    21061 atggattgac gtggtactac atcgtatatg gactgtatca tgcttgtctg atctgtctga
    21121 cagatgcatg gatccgattt aagaagaagc ataaagagca gttgccttct aacaaattta
    21181 cgcatggctt agccgtattt ttgacatttc aagcagtatg ttttagcttc ctgatttttt
    21241 caggattttt agataaactt ttttttagct aacgaatagt gacatattaa tttatataac
    21301 aaaggagaaa aggaaaatgg aagaacaaat tttatcaatc ttagaagaaa taacaggaac
    21361 agatgaagta agaaaaaatc gtgatattga tctatttgat gaagggttgc ttgattcttt
    21421 agcatctgtt caattattag tcgagctaga cggagagctg gatatccaag tccctgtatc
    21481 tgaattcgag cgagaggatt ggagcacacc gaataaaatc attcaacaag caactgcatt
    21541 gaagggttga gtatgaaaaa gaaacttttt gctattttcg gcccggttgt tttagctgtt
    21601 ggcttactgt ttgtgttttt tacctcctcc tatcaagtag atatctctaa tccagaaacg
    21661 attagacgtg cctcttcttc catgtcagtg aacgtgttga aaggagatgc gataaaaaat
    21721 tatgcattat ctgaaaaaca atatattcct ttttttggct caagtgaatt aagcagaatc
    21781 agtccatttc atccgtctgt tctggcagaa aaataccagc gaaactatcg tccatttttg
    21841 ctgggagcac ccgggacaca atcgttaagc caatatatga tgatgcgttc tgcaggagat
    21901 gctatgaaaa acaagaaagt cgtctttatt atttctcctc agtggttcgt taaaaatggt
    21961 gtaaaaactg attactttaa tacgtattat tctgaacttc aaacatacga ctggttgttt
    22021 tcaatgaaga aagtaacgcc tgctgatcgc tatttagcta gaagattatt aactttctca
    22081 aaagtaaaag agaatgatac gttgacggcg attctgcaaa cgatcaaaaa agggaagcta
    22141 cctttacctg aatctttgaa tcagctgcgc agccaatgga acatgctgaa gagagaggat
    22201 gaagtattca gcaatattgg gttgaaagat cgacagcaaa aaatcgatca tgagtcaaaa
    22261 cgattaccaa aacaatacca agaaacagaa ttatccattt tagcaaatca aattggagaa
    22321 cgagaaacga cgaataatcc attcgggttg aaaaacgatt tttatacgca tcgtatccga
    22381 gcccacgagc cagagctcaa acagtcacaa aaaaattggg attatcgttt ttcgccagaa
    22441 ttttctgatt ttcagctggt cttggatcaa ttagcaaaaa accataacga agtattgttc
    22501 atcatcccac cggttaacga gaaatggagc gattataccg gactatctca agaaatgtta
    22561 caaggatttg ccaaaaagat caaatttcaa ttaaatagcc aaggattcaa tcgaatagct
    22621 gattttgtca atcaagcggg taccaactat tttatggaag acacgatcca tctaggctgg
    22681 aaaggctggt tggctgcaga tcaacagatc agaccgtttt tagaagaaaa tcatattact
    22741 gctagtaagt atcatcttga cgatgctttt tttagcaaat cttggcaaca tcaaatacca
    22801 gataaactac aattaaaata aagaaaacag gcgagtgttg ctcgcttgtt ttctttattt
    22861 ttgaatattc tgaataaaag ataaaaatac caagtttgcc tgaacaaaaa tcataagcaa
    22921 tggtataatc acaatatgaa tatagaaatg ggggaaaaca tttggataca aaagaagaac
    22981 agctacttat tgatttaact tctgcaaaag gagtacctgg aaatgaagaa gaggtaagag
    23041 aagtattcag agaatatgcc aaaccattcg ctgatgatat tttttatgac ggtttaggca
    23101 gtgtgattgc caaacatggt gctggcggag gccccaaggt ctttatttct ggacatatgg
    23161 acgaagttgg ttttatggta acaaaaataa ccgaaaaagg attcttggaa ttccaaactc
    23221 ttggaggttg gtgggggcaa gtcatgcttg ctcagcaagt tgaaatcaaa acacgtgaag
    23281 ggaaaatcgt ccacggtgtg attggttcca aaccaccaca tgttttaaca cctcaagtaa
    23341 gaaataaacc ttatgaaata aaggatatgt tcattgatat tggcgcatca agccaagaag
    23401 aagccaaaga gtggggcata cgtcctggag atatggtcac tccatatatt gaatacaaac
    23461 gaatgaatgg cagtaaatat ttactggcaa aagcatggga taatcgtatc gggacagctg
    23521 tttctctgcg agtattagag aatctatcta aagaagcaca cccaaatgtt ttattcgcag
    23581 gaagcgatgt gcaagaagaa gtaggcttgc gaggtgctcg aacaagtaca caccttgtaa
    23641 atcccgatat tgcttttgct ttagatactg gtacagcagg agacactcca ggaatgacac
    23701 caaaagaagc agattcgatt ttaggaaaag gcccacagat tttgattttt gatgcatcta
    23761 tgatcccgca taaaaaatta ttgaattttg ttattgatgt agcagaggaa atggatattc
    23821 cattccaata tacagtgatt tctggcggag gaactgatgc aggacaaatg catttgacaa
    23881 gagatggtgt tccgtctgta gccattaccg ttcctgttcg ttatctgcat tcccatacat
    23941 cagtgattca tgaagatgat tatttgaata cagtgaaact agtcacagaa ttagtgaaac
    24001 ggcttgatag tgaaacagtt gaaaaaattc ggagttatga ataatgaata atagaatacc
    24061 tatttctgaa tatcggaaaa aagcacgagt ttctttggaa aatcaatggg gaatcaatac
    24121 ttggcttgtt ttcttatcta taatatttac gagcgtcatc cagaactttt ttgacggttt
    24181 cagtcctttt ccggaagaaa gcatgcagca gcacttattg agttttctag tcgataattt
    24241 acttttattc gcattcaact atgcattgtt ttacattgcg ctagtagttg tacggggtgg
    24301 cagaccaaaa agtaaccttt tattttcagt tttccaaaga aagtattttg gttcgatact
    24361 tggcatcaat ttgatcaatt cagtcatcaa ctggctactc aacagtttaa tctttctgcc
    24421 catgttttta atcagcggag tgagtactta tatgcagctg cttttcagtt caaatgcggt
    24481 acctacgggt gtcatgccag aagattttct tgatatcagc tttgttttat cgatgatagg
    24541 gatgattttt gtttcagcac tcatcatgag tattgttggc ggtttattcc aatttgctgc
    24601 atggacaaag ttcgactatc ctgatttgtc ggttattcaa tgtttgaaat atggctggtt
    24661 tttattgaaa gatagaattg gtacgtatat tttgttgcag ctgtctttta tcggctggta
    24721 tttgctagga gcaatcgctt tgttcatcgg tcttttgtgg gtcattgttt atgtgaatgt
    24781 gtcagttgca gaattttatg aacaagcacg gattgaaaaa ggaggtccag acgcctattt
    24841 tacttagcat gtaagcagtt tattcatcaa aaaaataact tttgtggtag gataaatctt
    24901 tgagggggaa tgtacgatga aattaactgt tttaggatgc ttaggagcgt atccttataa
    24961 aaatcaaggg acaacaggtt atttgcttca atctgacggg ttcaatttgt tgatcgatgc
    25021 aggtagtgct acgctgatca aattacaaga acaccttgat ccacttgatc tagatgctgt
    25081 gatccttagc cattatcatc atgatcatat tgctgacctt ggtgtattac agtattactg
    25141 gcaacttcat cctaagagaa atccggagac attgctttca atttatggac acacaaaaga
    25201 ttccattcac tttgaagaat tgacgttgga aaatgtctca aaaggacatc cttattttga
    25261 agctgaagaa ttaaaaattg gtccttttct gattactttt atggaaacaa tccatccagt
    25321 agtatgttac gccatgcgta tcgtagaaga aacaacgggg aaagtattcg tatttacagg
    25381 tgattcaggt tatttggaaa gtttcgctga ttttgcgaaa gatgctgatt tgtttctagc
    25441 agatacctat ctttttgaag gaaatgaaca tcatcatgcc catttcactt caaaagaagc
    25501 tggagaactt gcgaaatcag ctaacgtaaa gaaacttgta cttacacacc tacctcagtt
    25561 tggtgattta gaacaattga aaaatgaagc gcaaaaggca gcaggcaaag ggattgatat
    25621 agaacttgct gcagttgaca aagtgtttaa catttaggag gaagaacatg atttttgtac
    25681 caaatgaaaa ccacgaccca agaatcaatt tagcaattga acaatatttg ctgcaagaaa
    25741 tgcctttaga tgaacctatt ttgctctttt atatcaatga accttcaatc atcatcggca
    25801 gaaaccaaaa tacgcttgaa gaaatcaatc gagattatgt ggaagaaaat ggcattcatg
    25861 ttgtccgtcg cttaagtgga ggcggagctg tctaccatga ttttggaaac ctgaacttta
    25921 gttttatcat gcctgatgat ggggattcat tccgtgactt tgcgaaagta acacagccaa
    25981 tcatccaagc acttcatgaa ttgggtgttg ctggggcgga attgaaaggc cgaaatgatc
    26041 tagtcattga tggcatgaaa ttttctggca acgcgatgta tgctaccaac ggtcggatgt
    26101 ttgctcatgg aacaattatg ttcgactctg atatcaatga agtagtcaat gcattaaaag
    26161 taaaaaaaga caaaatcgaa tcaaaaggaa tcaaatcgat ccgttctcgt gtaacgaata
    26221 tcaaaccatt tcttccagaa gaaaagcaaa aaatgacaac agaagaattt cgtcaagaaa
    26281 tcttgttgaa aattttcggc gtagagtcag tagaagaagt aaaaacgtac gaattgactg
    26341 atgaagattg gaaaaaaatc aatcgaatct ctgaggaata ttatcgaaat tgggattgga
    26401 attacgggaa gtctccagat ttcaatttct ctcgccaaaa acgtttttct atcggttcga
    26461 ttgaagtcca tttgaatgtc tcagaaggaa tgatcaaaga agcaaaaatc tttggcgatt
    26521 tcttcggact aggagatatc tctgacgtgg aaaaaaaatt ggttggacag aaatatgata
    26581 aagcatctct atcaaaaata gtcagccaaa ttgatgtgaa gaaatatttt ggtgcgatag
    26641 aaccagaaga attgcttacc ttactttatt gaaaataaaa aatagcggaa tccacatata
    26701 tggattccgc tattttttat acaggattcg ggtaatttcg agagagttga acagtgatcc
    26761 gatcaatgaa agtatctttt tcctgcgtta gtgttcctgt gtaacgatcc gctacgtctt
    26821 tcatcatcat taagtcaaaa cgttcctgat catctaattc ttctgtgatg cctcgactaa
    26881 ataggtttgt atcgtaatgt gcactatgtt cgcaacaaat gacgaaatgt tcctcttgtt
    26941 cgtgtatcga caaataaatt tttcgataca gtggattttc gatggcatga gtttctctaa
    27001 aggaatgctc taaagcgtgg atcaaaagtt gagccagatc gtcatcgttg ataggaagtt
    27061 cttcgggaag atctgcttgg aaggttatct gaatattccg tttggcagct aacttctggt
    27121 aacgcgctaa gataagattt gtcacctggt ggttgcaaaa agaacacagc atttcgaaat
    27181 tttttgcttc ttctaatatc ttttccacat agtttttagc ttttgtttgg tccgtatgca
    27241 ttaaatcttg cagattctcc atctcttgga caaattccag gcgaagtgta tttacttctt
    27301 ggatatgctg tcgaagctgc tcataatgtt gctccaacaa atcatttttg atttttaaga
    27361 aatctacttg tctccgatct ttgtcggtat ttaagatgtg atcgattaga ttgtagctga
    27421 taataacgat tagaatgata atatataaaa tcgtagacca attgatcgtt gtttgataga
    27481 tacctaatgc cgtttggatg taaatcaagc aatggataat ggctaccaag acgatccaag
    27541 gtgtacaagc tacataaaaa cggttattct tatatgcttc gccaatgcat gcaagtgaag
    27601 tgactaaagt gcttataaca ctagcaatat tagcaatcgg cattaattca ggaagttctg
    27661 caggagtaaa agttgcataa agcagaacgc cgataaaaat caaaagttgg aacgtacaaa
    27721 aaattccgta ccatttttta tagtaaaaca ttcggctcca atagtagcag atgatgaaag
    27781 ctgacgttaa gataataaat aaatgagata aaaaagaatg aacgaatggt tcaaaaagaa
    27841 taccacttaa aatatcttct gatacagctt caaatcctaa tgccaaagca aagcaactta
    27901 agagaataag tgagtattca agacgttttt gtttatacat caagtagatc gtatagaaaa
    27961 aggtccctat agcgataaaa acagcgatta tcatcgtcaa tacttgcggc actgattgtg
    28021 aataaataaa actaatcaat ggtccagttg ttcctagata aactttcggt ggcagtccag
    28081 catagttctg ataaggagat gagactgtaa gggtcaattt ttttccgata taatttgctg
    28141 gtaaatctat cacagccaat gagagtccgg gattgctttc ttcctgataa tctttccgtt
    28201 ggtataaaat cttttcgcct agatatacag taatccattg atggtttcct ttgattagta
    28261 aatttgcttc gtccaacggt ttttcaagtg tcgtttccat aatgaatgtt tcgtctttat
    28321 ccacggtagg aatcgtacga gtgtacttgc tgtcaaactt aaaatcagga tcatcttttg
    28381 tatagaaaac ccacgaatct tttatttctt tcatttgatt gctgtccgca ggagaaaaaa
    28441 taaaataaaa gaaataagca attcctgtta aaaataacaa tgataatata atgattatgc
    28501 tccactttat acgtaaataa aaagattctt ttttattata tatgttatta aaaaaagaca
    28561 taaaggtatt cctttctaaa acttgtaatg ttagggtaaa cgttttttaa actaacgtca
    28621 attatttata ataaaaaatg agataaagat gaggaaatag aattagaaac atataattat
    28681 taaagggaaa catttttaca gctataattt gaaaaaaatt tatcgttatt atatgattaa
    28741 gaaggattga ataaagaaag aagttgaaaa cgatacctga ttacaaaaaa ataactttta
    28801 taagttctat aacgttgatt atatttttaa ttcttattct tctcgtcgtc ttggttcccc
    28861 gaatttttgg tttgactcct tatattattg aggacaaaga aatgagtcca tattatgcac
    28921 aaggaaatct gatatatgta cgaccgaaaa atacaaatga gattttagtc ggagatatta
    28981 ttacatatta tgaaaattca ggaaaaaaaa tctcgacgcg tcgcgtaata gccgttgaaa
    29041 acaaccacga agatttttat acaaaagctg atacaaagac ttatattgag cctggagtag
    29101 taaaaaagag aaatattatc ggtagtccca tctttcagat tccatatatt ggactagtcc
    29161 tttcaaaaac ggcatttgca tggattcagg ggttattctt tacgattgct ttttgcctaa
    29221 caggaatcac agcatggaat acctttgtag agttgaaaaa gaagcggaga cgaacacaga
    29281 aatttttgta agaatgttaa aaacataaat gtattccaga gatccaacga ctcttctgaa
    29341 catgaaacac gagaaaacac tcatgcagct tgtagattta gtcagttgtt cgtataatgt
    29401 gtgaagagga ggagtagtat gcgcaatgaa atgatgcatc gtcctgtagt caaagaagaa
    29461 ctattggatt ttatgcgtac ccagcaaaaa aaattaccgg gtgagctagg caaactggaa
    29521 gaagaagctc atgtagcaga agtaccagtt attccccatg aaacagttgt atttttgaaa
    29581 tttttacttg gacagcttca gcctgaacga atcttggaga tcggagcagc tatcggtttt
    29641 tcatcaagtg tcatggccac gacaatcgga gaaaacgctc atgttacgac aattgatcgt
    29701 ttcgatgtca tgatcgagaa agctaaaaaa aactatgaac gtctaggact gacagataaa
    29761 gtgactttgc ttgaaggtca agcagcagat atcttgccgg agttgtctgg tccgtatgac
    29821 tttattttta tggatagtgc aaaatcaaaa tatattgaat ttttacctga atgcttacgt
    29881 ttgttaagaa aaggtggcgt tttgatggta gatgacatct tccaaggagg aacgatcttg
    29941 ctcccagatg aagagattcc ccgtggcaaa cgagctatcc atcgtaaatt aaatgaattt
    30001 cttcgtgttg tgatggatca tcccgatttg acatcgacaa tcttgccatt aggtgatggt
    30061 gtgatcttaa tgacaaagga atcagaaaca atcgagttgt gatacatgat tatggcagcc
    30121 tgtagataat cgattgaatc gagggctcaa ttcgaacttg atgtaaaagt ttctatattt
    30181 gtaagtcaat taaaggatac aggaaatcta aataaacagg agtagcatga agtcaatgta
    30241 gctcctgttt tcaattgata accttagaac agctgaagga gaatgtctcg ttttaaaaga
    30301 ttgatttagt agttgggcca aaataattca ttatttgcta attaaataac tatttcgtat
    30361 tgacagaagc aatttaatta tctataatta ttgatgttcc gctgattctt gtcatagtag
    30421 ctcagctgga tagagcatcc gccttctaag cggacggtcg ggggttcgaa tccctcctgt
    30481 gacgctaaaa aaccgttaga aactgaggtt tctaacggtt tttctttgtt ttttgtgcca
    30541 atattgtttg ttttcaaagg caaataaaat aaaaaaacat ccttatcgag tacaattata
    30601 aggagcaaaa aaataaaact catcagaaaa gaggaagaag atatgacgat actatctaga
    30661 attttagtga ctctagttgc aattgaattt ttttatatca tgtatatcga aacggtgaga
    30721 actgattctg acacgacaag tagggttttt aaaatgagta aagaagagtt aagcagaaaa
    30781 tctgttcaaa cattgtttaa gaaccaagga gtgtacaatg gactattagg agtgggacta
    30841 ctttatggag cttatctttc ttccgcatct aaagaaatca caagtatgct attaatatct
    30901 attttttttg ttgcattata tggcagtttg actagcgatc gttggatttt actcaaacaa
    30961 ggtgggctag ctctgttggc attgctttct attttcttat aaatatagaa aaaataagaa
    31021 tttatctaac aggaaacttt gtgaaaaata ttactttatc tcatgaaata tgatattcta
    31081 atgaatggta ttttagaaaa tttcatgaaa aaggagttag ataggtgttc aaaaattatg
    31141 tttcctcact aaaaaaagaa ttttcaggtt atgatctttc aagatttcag aaagatcttt
    31201 tggctgggat cacagtagct gctgtagcat tgcctttagc cttggctttt ggggtatcaa
    31261 gcggagctga tgcggccgca ggtttgatta cggctatcat tgccggtatc gttattggcg
    31321 gtttatcagg cggtttttat caaatatcag gtccgacagg tgcgatggca gctatcttga
    31381 tgtctattgc ggcaacaaag ggaatgcaag gtgtattgct tgctactttt ttagcgggtc
    31441 tatttttact tgcagcagga cttttccgat taggaacact gacttctttt atcccagcac
    31501 ccgtaattac ggggtttact tcaggtattg ctatcattat tgcattaggt cagatcgata
    31561 atttatttgg tgttcactcg gaaggtacaa acgttattga aaaactaagt agttatcaaa
    31621 cgataggatt tccgataaac acagcctctt tgatcatggg agggctagtc attttaggga
    31681 tgtttatcta tccaaaaaaa tgggcgaaac gaatgcctag ttcgctgctg gctatcattt
    31741 tggcaacagc agttatgcta ttgttccatt taccagtagc aactgtgggt aagattccac
    31801 aaacattgat cagtagtaat cgtttgaata tgggagattt tagcttttct gccttgcaac
    31861 aagtggcagt tccagctatt agcattgctt tattaggaat gattgaaagc ttgctatgtg
    31921 gtgcttcggc tggccgaatg gcaaataagc ccttagatag caatcaagaa ttaatggcgc
    31981 aaggaattgg aaatctgttg cttcctttct ttggcgggat tcctgctact gcggccatcg
    32041 cccgtacaag cgtggccatc aaatctggtg cacaaactag attagctggt atgatacatg
    32101 cagttgtctt actgctctcc atgcttgttt ttgcgccagt gatgtcacag attccaatgc
    32161 cagcacttgc aggtgttttg attgtgacgg cttggcgtat gaatgaatgg gaaacgatca
    32221 aggagctatt tactaataaa tattggtcag cagttctatt gtttatcctt acgatgattt
    32281 gtacagttat ctttgattta agtattgcta tcgtgatcgg ggtgatcggc ggctgtgtat
    32341 tttttgttgt caaaagcgct gctatcacga tttcattaga aacgatcgat tggcaaagaa
    32401 tggggctgcc agaaacggaa aagctgaata actggacagt agtgtatatt agtggtccac
    32461 tgttttttat gtcttcagaa aaactcaaaa ataaattgga agaactaaat catcacgatg
    32521 gtgtcatttt ctccatgcga ggcgtaccaa gtattgattt gacggcacgt gcagtttttg
    32581 atgaatttca agaaaaagca gagcaaagag gacaaacgat tatctatact tccttgcagc
    32641 cagaagtaga aaaacaactt tctcacttgt gggaacatac attcacgcat caacatcaaa
    32701 cagttgctca tgcgttgaca gctttacatg cgaaatatac tgcaattagc cattaaaaca
    32761 atgaaaaaga acagacaaga ctgtaaactg aagattttat ggtcttgtct gttcttttta
    32821 atattgctgt aaaagtgaag ctagtacttg ccagtcttga tggataacag gtacaaggga
    32881 gcgattgtag aaaatagctg ctggatgaaa aagtggaaga attcgatagt ttttttctga
    32941 ccattcgtag gcatcctttt gttctgttaa ttgtaagaca ggccctgtat agagttgacc
    33001 atgatttttg gtaaccgtat attctttgcc aagtaaacgt tgaagaccaa tgtttccaag
    33061 tgtcgcaatt aattttggct ggaccttcat cagttcgtaa tccaatattg gtgcatgcgc
    33121 aaatacttcg gaacgagtag gtgtccgatt tggataaaca gtttctgact gttgtgtccg
    33181 tttattgatc cgatgagtca cgcgatacgg gcggctcctt acagcactgg tgatatacac
    33241 ctcttctcgt gttaagccag ttgaagaaag tgcctgcatc aattcttttc cagcttgacc
    33301 gctaaaagga acatgcgtat caatctctgt tttccctggg gcttctccca cgagcatcag
    33361 tttaggatga agaggtcctt gcccagcgat aaatccttct acaggacggc cgttcattct
    33421 taaagaagct tcttgtatca gttcttttgg gtattccatt tatgctcctc ctttttcttt
    33481 tattataaga ataaaagaaa cacaatgcga ctattttatt tggtagaact gtgaggatag
    33541 aaaagcagaa gtattgcttg aatttttgtt ttactttttg attttaaatt tagttgacta
    33601 acggttgctg ttctggtaag ctagtactgt tgtaattgtg gactccacag ctacaaccgc
    33661 tcagaacaag taataagcac agcatatgct gtcacttcgg atggcgagtc taagtatatc
    33721 agaaggaggt gctttatagc atgtacgcaa ttattaaaac tggtggtaaa caagtaaaag
    33781 ttgaagtggg acaagcaatc tatgttgaaa aacttgacgt tgaagcagga gaaaaagttg
    33841 tttttgacga agttatctta gtaggcggag aatctacaaa agtaggcgct ccaactgttg
    33901 caggtgcaac tgttgaaggt actgttgaaa aacacggcaa acaaaagaaa gtcgttactt
    33961 tcaaatacaa acctaaaaaa cattcacacc gtaaacaagg tcatcgtcaa ccatatacaa
    34021 aagtggttat cgacgcgatc aacgcttaat agcgtttgag aaagaaggcc tatatatgat
    34081 caaaggaaca tttaagcgaa atgacgcagg tcagatcgtt tcattcactt tgaccgggca
    34141 tgctgatgct ggtccttatg gaagtgatat cgtttgtgcg ggtgtttctg cgttagcgat
    34201 cagcactgtc aacgggattg cctcattagc cggttttgag ccgattgttg aaatgaatga
    34261 agaagaaggc ggttatcttt ataccgaagt cacttcagga atgacacaag aacaaaacaa
    34321 tattgctgag attctattag aaaatctttt attaggatta caatcgatag aagctgaaaa
    34381 ctcagaatat atccaaatta aaacaattaa tgataaatag gaggtgcaga ccatgttgtt
    34441 atctatgaat ctacaattat ttgcccacaa aaaaggtggc ggttctacat ctaacggccg
    34501 tgactcagaa tcaaaacgtc taggtgctaa acgtgctgat ggacaaacag ttacaggtgg
    34561 atcaattctt taccgtcaac gcggtacaaa aatctatcca ggtgtaaacg tgggtatcgg
    34621 tggagacgac actttatttg caaaagttga tggcgtagta cgtttcgaac gtaaaggccg
    34681 taacaaaaaa caagtgtctg tttatccagt agctcaagaa gcttaattga atcttatgat
    34741 taaagaggtt gtgacaagac ttttgtcaca gccttttttg tttataaaaa taaaagttgt
    34801 agtggaggct acgaagttta ctttgtcttt ttacacttaa tatttttttg ccaatttgga
    34861 atcaggatgt tttgataact atcgttttca attgatggaa gctatattgt ttgctatcag
    34921 tgaaataatt atatggtaaa cagtgttctt tttcttgttt ccattataaa aatcgtatcg
    34981 ggatttttcg ttcttttaaa ttgaacattt ctatctatcc gcgtgttatc aacaaaacaa
    35041 aatcaggtaa atagttgacg aaacagaaat aaatacatag tattatgttt tgaagcctaa
    35101 gtacaatagt ctatagaaaa ggagcgatac cattggcaaa acgcattgac cgaatttata
    35161 tgtatgtcaa agaaaaaacc gctcatttaa caaaggcaga atatgatcaa ggagtaacaa
    35221 cacaggaaat tgctgaagtg ttagggattc agcgaacaaa tagcagtaaa gatctgaatc
    35281 agctagtgcg cgaaggaaaa ctgataaaga cagacggacg accagtacgt tacatatatc
    35341 aaacactcgt tacgcacgta aagccagtta caaaacatgt agtcagttac aaagaaacgc
    35401 cggtctctga agaaaaaaat acactccaaa tagatactaa ggatatcttt gcaaaaatca
    35461 ttggagctaa cggcagcatg aaaaattcag tggaacaggc aaaagctgcg attttgtatc
    35521 cgccaagagg attaaattgt ttgattacag gacctaccgg atcaggaaag acttattttg
    35581 cacacgcgat gtatcatttt gcaaaagcgc atcatgtaat agatgaggaa acggaactga
    35641 ttgttttcaa ttgtgctgat tatgccaata accctgagct tttgatgagt catttatttg
    35701 ggtacgcaaa aggtgctttt acaggcgcag atgaagaaaa aatggggatt atcgatcaag
    35761 cggatggcgg tatgctgttt ttggatgaga ttcaccggtt gccgcctgaa ggtcaagaaa
    35821 tgatctttta ctttatggat catggaactt acagtcgtct tggggaaaca acgaaatccc
    35881 atgaagcaaa tgtacggatc gtaggtgcga ccacagaaga cccaggttct tctctattag
    35941 aaacttttgt tcggcgtatc ccaatcaata tcaaacttcc ggcttttgaa aaacgtcctg
    36001 caaatgagaa agtcgattta gtaaaaatca tgattgccca cgaagcaaac cgcacgcagc
    36061 gaaagatttc tttgacagaa gatgtagcaa aagcattgat cggcagtgtg acctatggaa
    36121 atataggaca attgaagtca aatatccagt tagtatgtgc acgaggattt ctaaatcata
    36181 tgcaatcacc cgaaatctcg atcacaatcg atgatttgac agaagggatt cgtagcggat
    36241 tgattcaatt agcaagcaac cgcagtgcaa tggcagagct ttctaaaata ttggagccaa
    36301 agataactgt agcaccaaat gatacgatca tgaaaatcca atcggactcc tatgagttac
    36361 cttataatct atatgatatc atcggagata aagcagcttt actgaagtcg gatggtttgg
    36421 atcaagaagc aatcaatcat ttcatttcta cagatatcaa catccatctg aagtctttct
    36481 ataaagacca tggtttttct tttaatgcag acagcaaatt agcagaattt gtagatccga
    36541 aaatcataga agtgaccaat cagatttatg taatggtcaa aagatcttta ccatatgagt
    36601 ttcagcaaaa ctttatttat gctatgagct tgcatatcag ttcttttttg aaaaaaatca
    36661 acttaggaga agaacggcat acgaatgata acatccgtga gatggctttt gattttccag
    36721 atgaatatgc tgttgcgaaa gaagtgcgta gttatatcga aacgtatttt caagtggaga
    36781 ttccagaaag tgaagactat tacttgaccg ttctactcgt ctcgttacgg gcaaatcaag
    36841 caagcggcag aatcggtgta gtcgttgcag ctcacggaaa cagcacagca agcagtatgg
    36901 tccaagttgt ccaacagttg ttagatgcag agaacgtacg agcagtagac atgcctttgg
    36961 atatggatcc gaaaacagca ttggaccgaa ttgaacgcaa tgtacaagaa gtagatgaag
    37021 gaagcggggt catactctta gtagatatgg ggtcccttgc gtcgtttaat tcgcaaattc
    37081 aaagagacac tggaattcca gtacgtactg ttgatatggt aacaacttct ctagttttgg
    37141 aaactgtacg aaaggtctca gtattaggga cagatctaga tatgttgcat gaatcattga
    37201 aaaattttcg aggttacgca gaaatatctt ctgtagaatc tgttcaggaa gcaaaaccta
    37261 ttcataagaa aaaagctgtt ttggctatct gcgcatctgg cgaaggtaca gcacaaagaa
    37321 tcaaagaatt gatcgaacga gcggtaaaca agcgtcaaga aacagaatta gaagttctag
    37381 ctttgtcgat tgtggaagtg aaagaagaac tgccagttat ccaaaaagaa tatcagatca
    37441 tagctactac tgggattact gatttgaata tccaagcccc atttattcct ttagaacgtt
    37501 ttattgatca aaatatcgaa gtcattttgg atcagttgct gatggaatca gaattggagg
    37561 aaactgaatt catctcccta gatgaagagt cagctaaaaa tacgtgtgtt gagtttatct
    37621 ctgataactt catctttatt aatggtagta agttaatcga tccaatgtgg caattttcta
    37681 cacaaatctc tcagacgacg ggaatcggcg atgaagaata tggattcaaa atcaacctag
    37741 tgatgcacac agcaggaatg atcgaacgta ttattcggaa tgaaccattg actgtggaag
    37801 aaaacgaatt gacaaataca acgaatgatc ctctttatag ccaattggca gcctcagttg
    37861 ttctgttgga agatcagata aaagtaaaag tgccgataga agaaatgtat tatctgctac
    37921 gtctagtcca taatcagtta gataaaaaag aatacactgt gccatgaata cacaaaaacg
    37981 atacactttt atagtgtatc gtttttgtgt attggttaag aatcctttaa attcaattag
    38041 tgtatcgtaa aaaagttggc acgctttttg cttatagtag tgtgtgctag gaggtggttg
    38101 ttcacacaga aatgataggg gtttctgtga agtagtgagg aagaaggagt tttgcagatg
    38161 gatattcgat tggcacgtat agatgatcgt ttaatccacg ggcaagtcgc aacagtttgg
    38221 tcgaagcaaa caggtgttga acgtatcatt gtgatcagcg atgtagtcgc tcaagataaa
    38281 ttgagaaagt ttctactaaa agaagctgca ccgccgggga tcacagcaaa tgtaataacc
    38341 gtgcagaaaa tgattcaaat ctatcatagt ggattattat cacgagcaaa agtgatgctt
    38401 ttattcacca atccccaaga tgttgaagcg gttgtccgct gcggtgtaca gttgaagtcg
    38461 ttgaatatcg gcggtatgag ttttactgaa ggcaaatcaa tgattaccaa ttttgtttca
    38521 gtaaatcaac aagatattga ttcctttcgt tacttgaaca gtcaagaagt ggagttagag
    38581 attcgaaaag tacctgctga caggaaaatc cttttgatgg aactactagc gaaaatcaaa
    38641 aaggtgtagc aagaatggtt gttggaaaag gtcaaataat tctgttgtaa tggttagcaa
    38701 ttattaatat ttttgaattt gttacaacaa aagtaaatag gaggtataaa tatggtaggg
    38761 attatcctag caagtcatgg acaatttgct gaaggaatct tacaatccgg ttcaatgatc
    38821 tttggcgaac aagaaaacgt caaagccgtg attttgaaac caagtgaagg tccagatgac
    38881 ttgagagcca aattggaaga agcggttgct tcttttgata atcaagacga agtgttattc
    38941 ttagttgatt tatggggcgg aacaccgttc aatcaatcaa acacattatt cgaagagcac
    39001 aaagataaat gggcaatcgt cagcggtttg aatttaccaa tgttgattga agcctacgca
    39061 tcacgctttt caatggaatc tgctcatgaa attgcagcac acatcattga aacagcaaaa
    39121 gacggtgtaa aagtaaaacc ggaagaatta gaaccggcag aagcaccgaa agcagcagtt
    39181 gaagacgcac aacctaaagg agcacttcca gaaggaactg tggtcggaga cggaaaaatc
    39241 aaatatgtat tagcacgtgt tgactcacgt ctgttacatg gacaagttgc gacagcttgg
    39301 acaaaagcag tgcaaccaaa ccgtattatc gttgtttcag atgcagtatc aaaggatgat
    39361 ctgcgtaaga gactaatcga acaagctgct cctccaggtg taaaagcaaa tgttattcct
    39421 attagcaaaa tgatcgaagt agcaaaagac cctcgttttg gaaataccaa agcattgctt
    39481 ttatttgaaa atcctgaaga cgtattgaca gctgttgaag gtggcgtaga catcaaagaa
    39541 ttaaatgttg ggtcaatggc gcattcggtc ggtaaagtcg ttgtaagtaa agtattgtct
    39601 atgggacaag aagacgttga agcgtttgag aagcttgaac aaaaaggtgt gaaattcgat
    39661 gtacgtaaag tacctaatga ttcacgcgat aacatggatg atattttgaa aaaagcaaaa
    39721 gctgaattag caaaagcgta ataaataata ttaaaattta taggaggctt atcatgtcta
    39781 ttatttcaat aattttagtc gtattagttg cctttctagc tggtatggaa ggtattcttg
    39841 atgaatttca atttcatcaa ccactagtgg catgtacatt gatcggttta gttaccggta
    39901 acctcgaagc tggtatcgta cttggcggta cgcttcagat gatcgcttta ggttgggcaa
    39961 atatcggtgc cgctgtagca ccagatgctg cattagcatc agtagcatca gcaattattt
    40021 tagttttagg tggacaaggt gttaaaggtg ttccttctgc gatcgcgatt gccgttcctt
    40081 tggctgttgc agggttgttc ttaacaatga tcgtacgtac aatcgctgtt ccaatcgttc
    40141 atttgatgga tgcggctgct gaagaaggaa acatccgtaa ggttgaaatg tggcacatca
    40201 ttgctgtatg tttacaaggg gttcgtatcg cggtcccagc agcagcgttg ctatttatcc
    40261 cagcacaaac tgtgcaatca ttccttgaat caatgccagc atggttaaca gatggtatgg
    40321 ctatcggtgg gggaatggtc gtagctgtag gttacgcttt ggtaatcaac atgatggcta
    40381 caaaagaagt atggccattc ttcgttattg gtttcgttgt agctgcaatt tctcaattaa
    40441 cattgattgc tctaggtgct ttaggtgttg cattagctct tatttacttg aacctttcta
    40501 aaatgggtgg ttcatcaaat aatggaggcg gaagcaactc tggtgaccct ttaggcgaca
    40561 ttttgaatga ctattaatct tgaaggagga aaataaaatg gcagaagaaa aaatcaaatt
    40621 atcaaaaaaa gatcgtttag ctgttgcgtg gcgctctacc ttcattcaag gttcatggaa
    40681 ctacgaacgt atgcaaaacg gtggctgggc attttctatg attccagcaa tcaaaaaatt
    40741 atacaaaaca aaagaagaac gttctgcagc attaaaacgt cacttggaat tctttaatac
    40801 acacccatac attgcttctc caattttagg ggttacattg gctctggaag aagaacgtgc
    40861 gaatggcgcg cctgttgatg atgtagcgat tcaaggggtt aaagtaggta tgatgggtcc
    40921 tttagctggt gttggtgacc cagtgttctg gtttacagta cgtccaatgc taggtgcact
    40981 aggtgcttca ttagctatgg gaggaaatat ccttggacca atcatcttct tcttaggttg
    41041 gaacattatt cgttgggcat tcatgtggta tacacaagaa tttggctaca aagctggttc
    41101 taaaattact gatgaccttt ctggcggatt gttacaagac gtaacaaaag gtgcttcaat
    41161 tttagggatg ttcgtattag ctgcccttgt agaaagatgg gtatcaatca aattcttacc
    41221 agttgtatca actgtaaaat tagataaagg tgcttacatc gaatgggata aattgccttc
    41281 aggtggtgaa ggaatcaaga gtgcatttga acaagttaat aatggcttag ccctttctcc
    41341 tgaaaaggta acaacattac aagacaactt agaccaattg attcctggtt tagctgcatt
    41401 aggattaaca ttgttatgta tgtggttgct taagaaaaag gtttctccaa tcgttatcat
    41461 ccttggttta ttcgtagtcg gtgttgttgg acacgtcatc ggacttttat aatccataaa
    41521 aatatagctc gggcgttgtc ccgagctttt tttatatagt atactgttca taaacaaata
    41581 tctggaggga gaaaatggtt caatcaatca atacaaaagt agacttggta attgatgcta
    41641 cttcgtttac gggtctgaca gattacgggc aaatcatgat aggtgataat ggttttgagt
    41701 tttaccatgc gcgagataga cgcaaatata tccaaattcc atgggaagaa gtggattatg
    41761 tactagcatc agtcatgcta aagggaaaat ggattcctcg atatgccatt caaacgaaaa
    41821 aaaatggtac atacacattt tcttccaaag aacctaaaaa agtgcttcgt gcgatcagag
    41881 aatatgtaga tgaagataga atggtacaat cattgagttt ctttgatgta gtgaaacgtg
    41941 gtattcgtag tatgtttaaa cgcaagtaaa aaataaagaa aacttctaag aggaggtttt
    42001 ctttattttt ttactttgca gaagaaaata tgaaatagca aaaccaatta tttgtcccct
    42061 ttaaatccca tatgctaaaa ttgattagca aagaaggagg ttatattatg agttggttat
    42121 ggacattgat tgttggagcc gtgatcggag caattgcagg tgcgatcacc agtaaaggaa
    42181 attcgatggg ctgtgtaacg aatatcattg ctggactagt cgtttcaagt attggacaag
    42241 cgattttcgg cgaatgggga ccaaaagctg caggtatggc acttattcca tctattttag
    42301 gcgcagtgat tttggtagca gttgtctcat ttttctttgg aaaacgatca taagttttta
    42361 caaaatagta aactaaaagg agttgcagcg agactgtgac tcctttttgg ctttatttat
    42421 ttaaaataaa aagaagtttt ccggaaattt ttatttaact gtcgtgtacg aagaaaagtt
    42481 tgctataatg gaaaaaagcg tgcaaagaaa gagggagttt cattatgatg ctacgtgtag
    42541 aaaaattgcg caaaaaaatg caagaagaaa atttggattc atttttggtt accagtccgt
    42601 acaatcttcg ttacttaacg aactttacag gtacgacagg attagctgtt attactttgg
    42661 aaaaagcatt ttttattact gattttcgtt ataccgagca ggcggcagcg caggctcaag
    42721 ggtttgaaat tattaaaaat gtcggaccta tttttgatga ggtagcaaac ttagtacgca
    42781 aagaagaact gcactcatta gcttttgagg aaacaacagt ctcattttta gaatattcgg
    42841 ttttagaaga aatcatcgat gcggaattag tacctgtttc acagatgatc gaagaactca
    42901 gagaagtgaa agatgaagaa gaaatcgcta ttatcgaaaa agcatgtcat attgcggata
    42961 tggcatatga tcacatcctg aaaatgatcc aaccgggcat gactgagatt gaagtcgcaa
    43021 atcaactaga cttttatatg cgttctcttg gcgcttcagg tgtttctttt gatacgatcg
    43081 ttgctagcgg attgcgttcg gctatgccgc atggtgtagc aagcaaaaaa atcatcgaac
    43141 aaggtgactt gatcacattg gactttggtt gctattacga agggtacgtt tccgatatga
    43201 cacgtacatt cgctattggt gatcctgggg aaaaattaaa agaaatttat caaatagtct
    43261 tagatgctca attagcagtt attgatgctg caaaaccagg aatgactggt gtccaattag
    43321 atgcagttgc tagagattat atttcaaaac atggttacgg ggaagcattt ggacattcta
    43381 caggacatgg gatcggttta gagatccacg aaggaccaaa cgtttcttct cgtgcagaaa
    43441 agcaatttgt accaggaaat gtgatcactg atgaaccagg gatctactta ccaggaatcg
    43501 gtggagtacg tattgaggat gacttgttga tcacagaaga tggaaatcgt gtgttgactc
    43561 gttcaccaaa agaattgatc atcttatagt ttcatcaata gaagaagtaa gcgtaaaaat
    43621 cagtgttcac agactttgtt atagaaaatc actcgattta atgatacact atagaagaac
    43681 ttttaagctg taagagataa taaagttggg tgttttctcc aattcatagc agtttgcagc
    43741 tgatcggcgg cagttttctt accacgtgat cactatgccg catcatagag aattcggatg
    43801 tatctcgtgc ttaggcaaag ggaggaataa ataaatggca gatgaaaaaa atttgatttt
    43861 aaacgcaaac caagatttag gagagatcgt gatcgctcct gaagtcatcg aagtaattat
    43921 cgggattgca gcttctaaag tagaaggcgt atacggaatg cgcggaactt ttgccagcaa
    43981 tgtcactgaa ttattaggac gtgcagctca cggaaaaggt gtttacttag caaacgagga
    44041 agatggcttg aaagtagatc tttactgtta tctagaatat ggtgtttcag ttcctaaagt
    44101 agcaatggaa atgcaggaac gggtcagcca gcaagtcctt ttcatgacgg atatcgattt
    44161 atctgaagtc aatatccatg tagtagctgt tgttcctgaa aaattagaac aaccaacaat
    44221 cgaagaactt tttgaagacg aagaggaaga gaatgaataa agaattatca agacacgaga
    44281 ttcgggaaat ggcattgcag gctttatttc cattagactt caatgcagac ctaacaaaag
    44341 aagatgcgat tttcaacgca atcgaattag accaccgcga catgatcaac gaagatgaat
    44401 cagagtttgt tcctgtttat cttgatacgc tagttggcgg tgtctgtgca aaaaaagatg
    44461 aattggataa agtgattgaa aaacatttaa aaaacaattg gcacatcaat cggatctcaa
    44521 aaatggattt ggtgatcttg cgtatcgcga tttttgaaat gacttatgtg acagatgtac
    44581 cagcggctgt tgctttaaat gaagcaatcg agttggcaaa aacatttagt gatgaccgtt
    44641 cacgtaaatt cgtcaacggt gttttatcca atgtattgaa agaattagaa gctggggcgt
    44701 aagtcctagc ttttttctat gaatcatcat aaacctgtta taaatcggga aaattctatg
    44761 gtagaatgaa aacacaaaaa atatctggga gtggttagat ggcagaattg attaacggaa
    44821 aagaattagc tgaaaaaatg caggcagaga ttgctgaaaa aatccaaaaa ttgaaagata
    44881 atggtatcca tcccggatta gtcgttttat tggtagggga aaatccagcc agccaaatct
    44941 atgtaagaaa taaagaacgt gtagcaaaag aaatcggaat ccattcattg gtagagcgtt
    45001 atcctgagac gatttctgaa gacgaactac ttgcagaaat tgaaaaatac aatcaagatc
    45061 ctagttttca tggtatattg gtccaattac cattgccaaa gcatatagat gaagaaaaga
    45121 tcctgttagc tatccgccct gaaaaagacg tagacggttt tcatccgatg aatttaggca
    45181 gactccttgc gggtaaaccg gacaagattc cttgtactcc atacggcatc atgaaaatgt
    45241 ttgaagctta ttctatcgat ccggcgggta aacgagcagt agttatcgga cgaagcaata
    45301 tcgtcggtaa accgatggct cagctactct tgatggcaga tgcaactgtt actgttgctc
    45361 attctaaaac cgaaaatctg gctgaactgg cacaagaagc agatatttta gtcgtagcaa
    45421 taggacgtgg acattttgtc acaaaagaat tcgtaaaacc aggtgctgta gtgatagatg
    45481 tagggatgaa tcgtgatgct aacggtaagc tgatcggtga tgtgaaattt gatgaagtgg
    45541 agcctattgc aggctggatc actcctgtgc caaagggtgt agggccaatg actatcacga
    45601 tgctgatgta tcaaaccgta aaatctgccg aagcttttgg agcaggtgaa tagatggcac
    45661 aagaatattt aactgtcact acattaacga agtatttgaa aagaaaattt gatgccgatc
    45721 cttatttaga acgcgtatat ttaacaggcg aaatatcgaa tttccgttta cgtgccaatg
    45781 cccatcaata tttcagctta aaagatgacc atgcaaaaat atctgctatt atgttcaaag
    45841 gagcattcca aaaattacga ttccagccaa aagaaggaat gaaagtcctt gtcgttgggc
    45901 gtatttcatt atatgaagcg ggaggttctt atcaaatcta tgtagagcac atggagcctg
    45961 atggaatagg tgctttatat caagaattgg aagaacgaaa agaaaagctg atgaaggaag
    46021 gcctttttca agggcctaaa aaaatgctgc cacgtttccc aaagcgaatc gcggtcctta
    46081 ccagtccaag cggagcggtt atccgcgata tcatcacgac ggtgaaaaga agatatccaa
    46141 ttgtccaatt ggttttgttc ccaacagttg tacaaggaaa ccaagcagcg gacaatgttg
    46201 tcaggaatat ccagagagta gaagagatgg gcaatttcga tacaatgatc atcggtcgtg
    46261 ggggtggttc gattgaggat ttatggccgt ttaatgaaga gcgggttgct cgggcgattt
    46321 atcaagctaa tacgccggtg atttcatctg taggacatga aacagatacc acgatcgctg
    46381 atttagtagc agatgttcgg gctgccactc caacagcagc tgcagaatta gctgttcctg
    46441 ttttgtcaga agagttgatg cgcattcaag aacggcaagc tagattgcag caggcgtttg
    46501 tacgccagat ccagcgcaaa caagaacggt tcgagcgtgc tcgacgttcc tatgtatttc
    46561 ggcagcctga aagattgtat gaaggtcaga ccatcaaatt agaccagttg aaacagcgat
    46621 tatatcaagc tacacagcaa atttatcatg cgaaagaaaa acaaacgatc gcattaagcc
    46681 accaattgga acaagtggct ccgctttatc gagttaaagc agctcgccaa gaaactgctt
    46741 atctagaaaa acgcttagaa gagaaaatcc aacaatatat gaaacaacag cagcagcgtt
    46801 ttgctcaagc tgttcaatct cttgatttgt tgagtccatt gaaaatcatg ggaagaggct
    46861 acagctatac gacgttaaat gatcaagtag taaaaagtgt caccgagatt catcaagggg
    46921 atttgctgac gatccattat caagatggaa tcgttaaagg acaagtacaa gagatagaca
    46981 aaggagaata aaaatatgga aaatccaact tttgaagagt cactgcaaga attagaaaaa
    47041 attgtcatgc agttagaaca aggagacgtt ccattagaat cagctctaga ttcgtttaaa
    47101 cgaggaatgg aattaagcaa acattgccaa gatacattag ctaaagcaga agagaccttg
    47161 acgaaaatga tgacagaatc aaatgaagaa gttgattttg acggaaacga ggaaagctga
    47221 gatgagatta actgactttt cagctattca tctacctgct gtagaaaaag aaatcttgtc
    47281 ttttttagat gagcatacaa cggatagagg actctatgat gcgatgagtt attcagtgaa
    47341 agcaggcggg aaaagaatac gtcccttatt acttttaacg gccgttgctt cctttgatga
    47401 gcctattgat gttcccgtct atcaagtagc agctgcttta gaaatggtgc atacgtattc
    47461 cttgatccac gatgatttgc ctgcgatgga caatgatgat cttcgtagag gaaaacctac
    47521 caatcataaa gtattcggcg aagcattagc tatattggcc ggagatggtt tgcttacagg
    47581 agcattccag ctaatcagta tggcacactt aggtaattct cctaagcttc tgctgcttca
    47641 gcaattagct gtttgtgcgg gatcacaagg tatggttgct gggcaagctg cagatatcga
    47701 gggcgaatcg aaaaagcttt ctttagaaga attagcattt attcatgaaa gaaagacagg
    47761 gcatttgatt cgttatgcct tgctggctgg tggcatatta gcgaagcaac ctgaagaaat
    47821 cttattgcta cttcaacgat tagccgaaca tttaggttta gcttttcaga taagagatga
    47881 tctactcgat gtgattggta caacgaaaac attagggaaa acagctggta aagatgaacg
    47941 tatggaaaaa aatacttacc cgcgtttatt aggcctagaa aagacacgtg aggcgttgga
    48001 gattgagctg ttatccgcca acaagatcat agacaaatta gaagaggacg ttttttcttt
    48061 tgatggcggg ctgatgcgcc agatgatcaa gcaatttgat gtggagaaat gagggaaaga
    48121 atggaaaaag aacgcgtaga tgtattagcg gtcaaacaag gattatttga aacaagagaa
    48181 caagccaaac gttcagtgat ggctggtttg atttacaacg aaaaaaacga gcggtttgat
    48241 aaaccgggag aaaaaattcc agtgagtagt gaattaagag tcaaaggtaa aaaacttcct
    48301 tatgtttctc gagggggatt aaaattagaa aaagcactca aagcatttga tctatctgtt
    48361 gaaggaaaaa cattgttaga tattggtgca tccactggcg gatttactga tgcagctttg
    48421 caaaatggcg caaaaatgag ttatgcttta gacgttggct acaatcagct agcttggaaa
    48481 ataagacaag atcctagagt cgtcgtaatg gaaagagtga attttcgtta tgcaaaaccc
    48541 gaagacttta ccttaggaat tccagaagtt gctgttatcg atgtttcttt tatttcacta
    48601 aaactgatgc tgcctccatt acatgctatt ttaaaagaag agggagaagt gattgcttta
    48661 atcaaacccc aattcgaagc aggcagagaa gctgtaggga aaaacggaat tgttcgtgac
    48721 cctcagaccc atcaaaaagt tttagaagac attttgtcat ttgcggcaca aggtggatat
    48781 gatgtgctgg aattaagtta ttctccgatc acggggggag aaggaaatat cgagttcttg
    48841 gctcacttga ggaaagtacc cgaaagcgga acaatcaatt cagctattaa tatggcagaa
    48901 gtggtttcaa atgcacacga acagtttgac cataaataaa ttgtaactgt gaaaatcaag
    48961 tgagaagtat gcggattctt ctttattata ccaaggaaat aagctatcat tgattaagaa
    49021 gaatatgcta aggagcgaag acgtaatgag aaaaaaagat cggcatcgtt tgattactcg
    49081 attgttgagt gagcaagata tccgaaagca ggaagaattt gttgaaatcc tgaaaagcaa
    49141 aggaatatct gttactcaag ctacgatttc cagagatata aaggaactga aactgatcaa
    49201 ggtaccggct tcagatggcg gctaccgtta tagcatacca gctgaaacaa acgaagatgt
    49261 aaatactaaa ttggaaaaac tattaaaaga cgctttcgtg gcagttgacc aaatggaaaa
    49321 atttgttatt ttgaaaacat tgccgggaaa tgcttcggca gcagcaaatt tgattgataa
    49381 acgttacaag aaagaattat tttcgattat caatgatgac gataatgttt tgatgattac
    49441 acgaactgaa gaccaggcag ttttattgaa gaaagacttc ctgcattacc tttaagttga
    49501 ggagcgaatg tgatgctaca agaaatcagt attactaact ttgcgattat tccggaattg
    49561 cggctttctt ttcacgaagg aatgaccgcg ctgaccggag agactggtgc gggtaaatcc
    49621 attattatcg atgctttagg tctgttagca ggaggaagag gttcaagcga ttatatacgt
    49681 caaggagcag aaaaatgtgt gcttgaaggg ttgtttgaac taccaaaaca agaaggattc
    49741 tctgaactga tggttgaatt agggatcgaa acagatgagg acaatctgat tgttcgacgg
    49801 gatatgtcct taactggaaa aaatgtttgt cgagtgaatg gtcatattat cacattagct
    49861 aatctgagaa gaatcggcag ttatttagta gatatccaag gacaaaacga acatcaggaa
    49921 ctgctccagc ctgaatcaca tcttgcttta ttggatcgtt ttggagatgt agctttccaa
    49981 cagaagaaaa agagttatca gcaagaatat atctcttatc gtgagctgga aaaaagggta
    50041 cgaaaagtgc agcaaaatga aaaatcctat gttcagagaa tagatatgct ccatttccag
    50101 caagaagaaa tagctgctgc tgatttgcaa gtcggagaag aagagaaatt aaaagaagaa
    50161 agagaaaaac ttagcaatta tcaaaaaatt gctgatggat tagctgcagg ttacggagca
    50221 ctgacgaata atgaacaaaa cagtgtagat ggtgttggct tggccgtttc agaactgcaa
    50281 gggatcgccc atctagatgt ggagtatgaa gcaatttatg aaaatatcca aagtgcttac
    50341 tatttgctgc aagatgcaat cggcgatatg agtcgtcaga ttgatttatt ggagttagat
    50401 gagagtcgtt tagaagaagt tacgcaacgt ttagaattaa tccgacagtt gaaacgtaaa
    50461 tacggcgaat ccattgagtc aatattggct tactatgacg aaatcaccga agagctagct
    50521 tcttctgatt tttcagaagg tcaattggac aaaatgaaag aggaactaga gcaaaaagag
    50581 cttctacttc agcaacaagc cgcagatctt catgaagcgc gtaaaaaaat cgcaaaagaa
    50641 ttggaaaaat ccattctgca tgaattgaaa agtctgtata tggaaaacac tgagtttgag
    50701 gtacgtttct taaaagaaga aaatagacaa ttgaatcatg atggatttga ccaaatcgaa
    50761 ttttacatta cgaccaatcc aggagagcca ctgaagcctt tggtgaaagt cgcttctggt
    50821 ggcgaactgt ctcggatgtt gcttgctttg aaaactattt tttcttctga gcaaggtgtg
    50881 acaagtatta tttttgatga agtggataca ggtgtgagcg gaagagttgc acaggccatc
    50941 gcagataaaa tttctcaaat atcgaaatac tctcaagttt tgtgcatcac tcatctgcct
    51001 caagttgctg cagtcgccga ctatcaatat tatattgtga aagcagtgat tgatggacgt
    51061 acgcaaactt ctgtttcaga gttgaaaaca aaagaaagag aagaagaaat tgcacgtatg
    51121 ctggctggaa gtgagattac aaaactcaca ctcgaacatg caaaagaact attgaaactc
    51181 gcaaaaagga cctgagccac ctcgcagtgg ttcaggtcct tttcagcagc tgatagctat
    51241 attttatttt tacatgacac tcattacagc agtcaataca acagatccaa tcgttaaaat
    51301 cagcattgtc caaatgacaa attttgttac tttagcaaaa gtacttgttt gttttttttc
    51361 acgcattgtt ttcaacctcg tcattaatta gttgattcaa gtgtacaatc ttttttccat
    51421 ttccacaaga gggctttttt ataaaaactt cccttttttt aaataatagg tagttacgat
    51481 acaaataaat aatgttaata gaactagcca tataaaggca tcatcccttt cagcaatagg
    51541 taacttaatg ttcattccat agatactgcc gacgattgtc ggtatagtta aaataatcgt
    51601 taaagaagtt aaaattttca taatattatt cagattattc gatacgattg ctgaaaaagt
    51661 ctgattcatt tgttctacta gttttaattg aatgcgagaa gtagtcattg cctgctctgt
    51721 ttccaccaat acatcacgta aatgattttt caaagcatga ttttcttgga aaagtttatt
    51781 ttgcgctagt tctttcaatg catctaaatt agcagaagtc gcttctctga aataaacgag
    51841 gcttttttgg atatccatga tttgataaag ttgtttgttt tcagtggata cttgaagttt
    51901 ggcttccaaa gtatcgcatt gagattgaag cgtagctaaa taactgttgt aagagagtgt
    51961 gacctgccaa atgaattgaa agaagatatt gagattaggc gaaatatcac tttttggaaa
    52021 ggtctggcta aagactttct ttaaaaacag tggttcatga ttcgtaattg tgataagctt
    52081 ctttttgggc gtcaaaataa tagagagcgg gtatgtatcc acttgaaaat aaccgctagg
    52141 acttgtttta gcaaaaggat attgtaacaa taataacgct ggctttgtca actttgattg
    52201 attgaattct tctgtacggg aattttctgc atcgtccaat atggaagtga tgtaatctga
    52261 cggaatttca aattgatgtg tcagctgatg aatctcttct tgattaggac gttctacaca
    52321 ataccagatc gtttggtcag tttcctttcc ggtattacgc agtttctcat tatctaatgt
    52381 aaaatatttg atcatgattt tcctcctgtt gcctgtttct tttattataa cggataggga
    52441 attggaatac atggaatgtg tttgtaagat atagaatata actgcataaa tttaaataaa
    52501 atgaaacagt tgtgtaaagt atatacagta tacttgaagc aacgataaaa aaggagttta
    52561 cgttcatggg cacattcaca ccacttatct tgttttggta tatttacccg gtaatcgttt
    52621 tgtttggttg ccaatttctt gtaaaattat tttcgttaaa tcgtcgtttt aaaataaaag
    52681 cccctgattt ggcgattcct tttttgtggg gcggtatgca tgcattgtct agaaatacag
    52741 ggacaatttc tatcttaccg tttttcttta tttctgtttt gctaatggga atttgtattg
    52801 ctgttttcca agcatattat tatgaagaaa ttatttatcc gcgttatttc aagatgactt
    52861 ggcgtttggt ttttctgttg acaatcgtct tgtacgctgt cttgatcatt gtgaacatac
    52921 tttcttacct atgaaaaaaa tagaaaagct gtaaaaagtc ttttaaaagg ctttttgcag
    52981 cttgattttt aaaaaaatgt ttatgaataa aaaaagttgt tcccggattt cccagaaaag
    53041 gtggtagaaa gtgggggatt gtggtagact aattttagtt agtggaggaa tggggggctt
    53101 tcaatgttga tgggtgaatt ccaacataat attgatgcaa aaggacgttt aatcgtgccc
    53161 tcaaaacttc gtgaagaact tggcgaaaag tttgttctga cacgcggatt ggatggctgt
    53221 cttttcggct atccgatgag cgaatgggaa aatctggaag ctaaactgaa cgaaatgccg
    53281 ttggctaaaa aagacgcacg tacttttgtg cgattcttct attcggctgc cactgaatgc
    53341 gaacttgata aacaaggacg aatcaatata cccagcacgt taagaaatta tgcagctttg
    53401 acaaaaggtt gcgtagtcat cggtgtatct aaccgaattg aaatttggga tgagacacga
    53461 tggcaagatt tttctgcagc agcagaagag aactttgacg aaattgctga aagtatgatt
    53521 gatttcggac tataagaata ggaagaggct gactaatgac tgaaacattt caacactata
    53581 cagtcatgtt gaaagaaacg gtagatggat tgaacatcaa accggatggc gtttatgtag
    53641 actgtacact cggcggtgcc ggacatagtg aatatttatt aagccaacta agttctaaag
    53701 ggcatctgta tgcgtttgac caagatcaaa aagcaatcga tcacgccaag ctgcgtttag
    53761 cttcttatgt cgaacaaggt atggtcacat ttatcaaagc gaacttcaga gaattagaag
    53821 aacgcttgag tgagcatgta gataaggtag acggcatttt gtatgatcta ggggtttcct
    53881 ctcctcagct agatgaagca gaacgtggat ttagttatca tcaagatgca ccgttggata
    53941 tgcgcatgga tcagtcagct cctttatccg cttatcacgt aattaatgaa tattcctacc
    54001 atgaattagt aaagattttc ttccgctatg gcgaggagaa attttccaaa caaattgctc
    54061 gtgaaatcga acgagtacga aaaacaaaac caatccaaac aactggtgag cttgtcgaaa
    54121 tcattaaaca agtcatccca gctcccgcaa gaagaaaagg cgggcatcct gcaaaaagaa
    54181 tttttcaagc tgtgcggatt gcagtaaatg acgaactcgg tgccgaagag gcctctttag
    54241 aacaggcaat ccggttattg aaagtcaatg gaagaatcag cgtaatcaca ttccattcat
    54301 tggaagacag aattgtcaaa agtatgttta aagaatatag tacggtacaa gatctaccac
    54361 cgggacttcc tgtcatacct gacgaattcc aaccagaact gaaagtcatt actcgtaaac
    54421 caatccttcc ttcagaggaa gagctaacag aaaacaatcg atcacgcagt gcaaagttac
    54481 gtattgcaga aaaaataaga atgaaagagg agtagaatga tggcagaatt aaagaaaatg
    54541 caagattacg aatatgattt acctgaattg gtggatcagc cggaacaaca aatgcctgat
    54601 tcttcttcga atcaagaaat cattcttcca caatcaccgg caaaacgatt aaagcagatt
    54661 tctgctttgg aaaaaattgc tgtggcaagc gtggcgattg ctattgttgc tttatgtgtt
    54721 ttaacagtta tgctgcgcac aaatatcagc ggagctgaaa aagaaatcac gtcaatacaa
    54781 acagaaatca atgataaaaa gcaagaaaaa acgagtttag aacaagaaaa aaacgaactt
    54841 tctcgtactg aacggattaa acaaatcgca gaagaaaaag gattgtctat taatgacgac
    54901 aatttaagga aagtgaagta aatgagtctt aaaaataaaa ttcggcggtt tatggaaaag
    54961 aaaaatctaa atccgatgaa caatcgcaaa aaagtaggta tcattttatt tgctacgagt
    55021 attggaatgt tctttttatt tgccgtccgt ttctcgtata tcgttattgg aggtcatgtt
    55081 gctggtacct cattagctga aaaaacaaaa cagttgtacc aaggaagtga agtagtaaaa
    55141 gcaaaaagag gaacgattta tgatcgtaac ggtgtggcgc tcgcagaaga tgcctcctct
    55201 tattcaatta aagcgatact ctcaaaaaca tatacctctg gggataaaaa actgtatgtt
    55261 gaagaaaaga attttgataa aatagcagaa atcctgcata agaatctttc tatagacaaa
    55321 aaagatgcac tgaatatttt agaggacggc gcaaaaaaag agctgtatca agttgaattt
    55381 ggtagctatg ggaaaaatat ctcccaagaa accaagcaaa acatcgaagc ggacatgaaa
    55441 aaagaaggtg tcgctggtct ttattttgtc gaccatcagg ctcggatgta tccaaatggc
    55501 gtcttttctt ctcattttat tggatacgca gttccagaca aagatgagaa tggcttagtt
    55561 ggtaaactag gtttggagtc tgcttacaat gatatcttga gcggtaaaga tggtaagatt
    55621 atttatcaaa aagataattt tcaaaatcct ctgccaggta cagtggcaga agaagaaaaa
    55681 gctgtcgacg gacaagatat ctacacgact ttagacagca gactacaaag ttatttagaa
    55741 acactgatgg atcaagtaaa tgaagaatat cagccagaag aattgacagc agtcctgatg
    55801 aaagcaaaaa ccggagaaat cttggcaatg ggacaacgac ctactttcaa tcctgaaaca
    55861 atggaaggat tgactggaaa agatgctatc tggcgtaatt tcttggtaca agatagttat
    55921 gaaccaggat caaccatgaa agttttcact actgcagctg ctatcgaaga aggagaattc
    55981 aacgagaatg aaaccttcca atctggaaaa atccaagtag aagatgctac gatcaatgac
    56041 catgactttg gtgaaaaagg tgtgctgacc atgcgtcaag ctctttcatg gtcaagtaac
    56101 gtcgggatgg tcatactgga acagcgatta ggcggacgat ggtataacta tttacaaaaa
    56161 ctgggatttg gacaaagtac tcattctgga ttagatgatg aagtaaacgg tgctttacct
    56221 acattaaata ttgtcgaccg agcaatgagt gcttatggac aagcggtagg tgtgacgaat
    56281 ttccaaatga tgaaagcttt cacttctatt gcgaataacg gtacaatgat tcaacctcga
    56341 tatatcagca aagtggtgga tccccaaact ggagaagagc gaacaactca aacagaagtt
    56401 ctagggcaac ctttttcaaa agaaacaaca gaaaaagtcc gtgaatatat gagagatgtt
    56461 gtcgaaagcg aaaactacgg tagtgcttat ggtgtatata gtgtacctgg atacaatgta
    56521 tcggcaaaaa ccggaacagc ccaaatcgct tctgatacag ggggatatca aacaggagat
    56581 acagcctacc tgtattcgat tgtggagatg gttccttctg aagatccaga ctatgtcttg
    56641 tatctaacaa tgaaacaccc taagacatat gatcgaatgg cattggctaa aatcgcaaat
    56701 ccattgatga aacgggcaat ggattttaaa gaaactgaag aagattcaga tacagaaaca
    56761 aaaacagaaa aagtatccgt agccgattat cgtaatcttg aagcggacgt tgcagcagct
    56821 gatgctcaaa aaagtggact gcaacctgta gtgatcggta atggtaaaaa agtacaaaaa
    56881 caatctactg ccaacggtga tcagttgatc tctggagaaa aactgatcct atatactggt
    56941 ggtgataagc tgatgcctga cgtaacagga tggtcaaaag cagatatcat gaagctgggg
    57001 aaaatcctcg gtattgaagt tagttttgat ggagatggtt attgtgtcaa acaagaactt
    57061 gctccatatg aaaaaatcac tgaagacaaa cttagtttta ctttagaaga ataagaagag
    57121 aaataggaga gaaaagagca tggaatggac acaagcattg attcccattg tcagcagttg
    57181 tgcaatgaca attgccgcaa tgccgctatt tattggttat tttcaaatga aaaagcaagg
    57241 tcaggcgatt cgtgaggagg gaccaaagtg gcacaatagc aaagccggaa ctcctacaat
    57301 gggcggctta gtgtttctga tcggctctat tttgacagga atttgggttg gagcttggca
    57361 aaaacagcta actcctactc ttttcatctt gctttttgta ttagcgttat acggagtaat
    57421 cggctttctt gatgatttta taaaaatatt caagaaaaga aacatgggac tgaactcgaa
    57481 gcagaaattg attggacaga ttctaggggg aatcatcttt tatcttgttt accgttctga
    57541 aggttatcca ggtgtattga atttcttcgg actagatcta cctttaggaa tcatttatgg
    57601 tattttcgct ctcttctggc ttgttggatt ttcaaatgca gtaaatctga cagatggcat
    57661 cgatggatta gttgctggct taggaagtat ctcttttgca gcttacggtc taattgcttg
    57721 gcatcagcat cagtatgatg tattaatcat ttgcttaagt gttttaggag gtttactggg
    57781 tttcttcgtc tacaacagaa aacctgccaa gatttttatg ggagatgtcg gttcattagc
    57841 gttgggcgga cttttagcgg caatttctat aatgctaaac caagaatgga cattgctttt
    57901 gattggtttg atctatgtta tggaaacagc aagtgtgatg cttcaagtta cttcctttaa
    57961 gcttacagga aaacgaattt ttaaaatgtc tccaattcat catcactttg aaatgtgcgg
    58021 atggtcggag tggaagattg atacagtttt ttggttgatc agcattgtga cttcgttgat
    58081 cacattatgg atcgtttggt aggagatgac gggaaatgaa aaaaatatca acatatgaaa
    58141 ataagaaagt gcttgtctta ggactcgcaa aaagcggagt aagtgcggcc aaattattac
    58201 atgaattggg cgcacttgtc accgttaatg atggaaaacc ttttgacgaa aatccggaag
    58261 cacaagagct gctttcttta gggataaaag taataacagg tagtcatcca atcgaattgt
    58321 tggatgaaga attttcattg atggtcaaaa atccagggat tccctacagg catcctttag
    58381 tagcaaaagc ccaagaaatg ggtattccgg taattacgga agttgagcta gcttacgaag
    58441 tagcggaatg cccaattatt gggattacag gaacgaacgg aaaaacaacg acaacaacga
    58501 tgacaggact actactgaat gcaggagcag atcaaggaat tgcacgttta gcgggtaata
    58561 ttgggtatcc agcaagtggt gtagcgcaag aagcaaaatc agaagataaa attgtgatgg
    58621 aattgtctag cttccaactc atgggaatca cagatttccg ccctcatata gcggtgatta
    58681 ccaatatcta tgaagcacat attgattatc atggtacaag aaaagaatat gtcaaagcta
    58741 aatggaacct tcaaaaaaac atgacagaaa aagattatct gatccttaac tggaatcagt
    58801 cagaactaca agaattagcg caaagaacaa aagcacgcgt actgcctttc tcgacaaaag
    58861 aagtgttgga agacggtgtg tatgctgacg attactcaat atactataaa aaagaaaaaa
    58921 taatggaaat atctgaactt ggcgtaccag gtaagcataa tgtagaaaat gcactagctg
    58981 ctatttctgt agcaaaattg tatggtatat caaatgaagc tatacgagaa acgttgcatt
    59041 ttttccatgg cgtaccacat cgtacgcaat atgtaggaga aatccaaggc agaaaatttt
    59101 ataatgattc aaaagcaacc aatattttag cgactaaaat ggctctaagt ggatttgaaa
    59161 cgtctaaggt cgtgttattg gctggcggat tagacagagg aaatacattt gatgaattaa
    59221 ttccttcatt aaaaggaatc aaagcaatgg tcgtatttgg ccaaacaaaa gaaaagttga
    59281 tggatgctgg aaaaaaagca ggcatcgaga caatagtaac agccgattct gtagaacaag
    59341 cagttccttt agcattagaa aacagtacag atggtgatgt agttttatta tcaccagcga
    59401 atgccagctg ggatcaatac ccaaattttg aaactagagg aaacagattc atggaagctg
    59461 tgaaccgatt aaaatagaaa aagtagaagc gagcgataaa aaatgaaaat tttggttaca
    59521 ggcggaggaa cagggggaca tatttatcca gctcttgcct ttgtcaatta tgtaaagact
    59581 caagaaccga atgctgaatt catgtatgtg ggagcaaaac gaggtctaga aaacaaaatc
    59641 gtccctgata caggaatgcc tttccatacc ttggagattc aaggatttaa acgaaaaatt
    59701 tccatgcata acatcaagac ggtccgattg tttcttaaga gtatccgtca agcaaaaaaa
    59761 atcctcagtg attttcaacc agatatcgtt atcggtactg gaggatatgt ttccggagcg
    59821 gtagtgtacg ctgcagccaa aatgggtatt ccaacagtta tccatgaaca aaacagtgta
    59881 ccaggtgtta ccaataaatt tttaagccga tatgtggatc ggatcgctct ttcatttaaa
    59941 gatgcggctt ccttttttcc tgaaaacaaa gcagttcttg taggtaatcc tcgagcacaa
    60001 gaagtagcag atactaaaaa atcagatatt ttgaaaacat ttgatttgga tccagaaaag
    60061 aaaacagtct tgatttttgg cggtagtcaa ggagcactta aaatcaatca agcagtatca
    60121 gtttttttaa gtgaatatat tccttcttct taccaagttt tgtatgcttc aggagataga
    60181 tattatgaag agatcctaaa taaaataaat cctgaaatac aaaatattag tgtccagcct
    60241 tatatcaaaa atatggcaga ggtcatggct tccagtgatc tgctggtggg gcgtgctggt
    60301 gcaacttcga tcgcagaatt cacagctctg gggttaccgg cagtgttggt tcccagccca
    60361 tatgttacga atgatcatca gactaaaaat gcaatgagtc ttgttcacgc aggagcagca
    60421 aaaatgattg cagataatga actaacaggt gaatcactaa gtcagacagt caacgaaatc
    60481 atgggtgatg aagaattgca aaagcaaatg tgccgagctt ctaaagaaca aggaatccct
    60541 gatgcttcaa aacgtcttta tgacttagta aaacaaataa tcaaaaaata aaggcggtgg
    60601 tcttagtgag taagaaaaaa gaaccaaaaa aattgtctca tccgtcttct gatgaaaaca
    60661 atttgactcc ttggcaaaag gctaaccgaa aatatctggc agaacaagag atgaaaaacc
    60721 aagagccaaa aaaagaagac ataacattag atacacccct ttcagattct gaagaagaaa
    60781 aaacggttca agaggaacag caagaagaaa gccagtccga gaaaaaaatc gaattttttg
    60841 aagagatcaa gcaaaagaaa aacggtggac catataacgg ttcttttttg aaccggctgc
    60901 ccaatttaaa aagtcaacgg cacaaagtac tatttcgtcg gttagctttg atcatcactg
    60961 tattgggtat accgctgatt tttttgatct attatgtttc tccttatagc aaattacaag
    61021 cagttgcagt atcaggcaat aagacagtca acagccaaga aatcatctct gatacaaaat
    61081 tgtcattagg agaaaatgtt tggggacagt attttcatcg atctacttat atcgatcgcc
    61141 ttaaaaaagc acagccaaga atcgaaacag caaatataca tttcaaaggg atgaatgaat
    61201 tcgatttgga tgtaacagaa tataaagaga ttgctttgat cgcaaaaaac aatcaatact
    61261 acccagtgat tgaaaatgga acagtattag atgaaaaagt agcaaatcct acaaaaaatc
    61321 tccctatctt ggaagagttc aaagactctg caaaaatcaa agaattaaca aagcaataca
    61381 atcagttatc atcagaatta caaaaagcaa tttctgaaat caagtacacg ccaagagcaa
    61441 gcaataaaaa tctgatccaa ttgaatatga atgacggcaa tcaagttatt gtaaatatca
    61501 ataatcttgc gaaccaaatg aaatattatt cgcaagtagc caaagatatg gatgaaaaag
    61561 gtgtgatcga catggaagtt ggtatcttct cgcatcctta cggtagcact caagaaacgg
    61621 aagaatcggg ccaatcggaa gaaacaactg aaagtgaaga aaatgcggat caaacaaacg
    61681 aatcaagtga agaggcagaa acgcaaaaag cacaaacacc tggatcgtct agcacaaacg
    61741 gatcatctga ttcaaatgat tcaagtgaaa caagtcaaat agaagataat ccaagtacaa
    61801 ctccgtcaag tttaaatgaa aattgataaa acaactttaa aaagtaagaa tgtactttct
    61861 aaaaaccagt aatttatggt agaattggaa gcagtgaata tatctattaa taagtatatt
    61921 ttaaaacgga cgctagttgt tcgcttgtat atggaatagt aagtaggagg gaatcccatt
    61981 catggcaaaa acaggaatgt atgtaggcct tgatattgga acgacatctg ttaaagttgt
    62041 cgtggctgaa tatatcgaca gccaaatgaa tattattgga gtaggaaacg caaaatcaga
    62101 agggattaac cgaggcatta tcgttgatat cgataaaacg gtccaagcga tacaacgagc
    62161 agtacgacaa gcagaagaaa aagcaggtat ccagatcaaa ggcgtaagtg tcggtttgcc
    62221 agcaaacatg cttgaagtag aaaattgcca gggaatgatt gcagttaacg gagattcaaa
    62281 ggaaatcacc gatgaagatg tcagaaatgt ggcttcagct gcccttgttc gttcaatacc
    62341 tcctgaacgt caaatcgtgt caatattgcc acaagatttt actgtcgatg ggttcgaggg
    62401 aatcaaagat cctcgtggaa tgatcggcgt aagattagaa atgtacggtc tgttgtttac
    62461 aggacctaaa acgatcatcc ataacatacg taaatgcgtg gaaaatgccg gattaatcgt
    62521 caacgaaatg gtgattactc ctttagcgct gactgaatca attctttctg acggagaaaa
    62581 agattttggt acgatcgtca ttgatatggg tggcggccaa acaacaacgg ctgttatgca
    62641 tgataagcaa ttgaagttta ccaatcttga ccaagaaggt ggcgaatttg tcactaaaga
    62701 tatctctatt gtattaaata cgtcatttaa caatgcagaa gcgttgaaaa taaactacgg
    62761 ggatgcatac ccagaacgga catcaccaga tgaagaattt ccagtagatg tgattggtca
    62821 gtcagaacca gtgaaagtcg atgaacgcta cttgtcagaa attatttcag ctcgaatgga
    62881 acagattttc aacaaagcaa aagatgcatt ggaccaaatc gaagcattag agttgccagg
    62941 tggcgtcgta ttgacaggcg gagctgctag tcttcctggt gttgtggact tggcacaaga
    63001 aatcttcggc gtaaatgtaa aattgtatgt tccaaatcac atggggctga gaaacccggt
    63061 atttacaaat gtaataagta tcgtggatta ttcagcaaac ttgagtgaag tgtatcaatt
    63121 ggcaaaaatt gctgttacgg gtgaaacctc agcagctcgt caaatggtag ttgaacaaga
    63181 aacaacaaac acatatgaga gctatgaagc acctgaagaa acaatctacg atgagccgga
    63241 accaaaagag tccggagaaa atgtaaaaaa taaaatcaag ggtttcttta caaatatttt
    63301 tgattaattc atcctgggag gaataagata tggaattctc aattgataat aatatcaatg
    63361 acggcgcagt aatcaaagtc atcggagtcg gtggtggcgg tggaaatgct gtaaaccgaa
    63421 tgattgaaga aaacgttaaa ggtgttgaat tcattacagc caacacagac gtgcaagcat
    63481 taaaaaattc aaaagctgaa acagttatcc aattaggccc caaatatact cgtggtttag
    63541 gtgctggttc tcagccagaa gttggacaaa aagcggcaga agaaagtgaa caatccttac
    63601 gcgaagcttt agacggtgca gatatgattt tcatcactgc aggaatgggt ggaggaaccg
    63661 gtacaggtgc tgcaccaatc gttgcaggta tcgcgaaaga attgggcgca ttgactgttg
    63721 gtgtcgtgac acgtccattc acttttgaag gaccgaaacg tggccgtttt gctgcagaag
    63781 gtatcgctcg tttgaaagaa aatgtggata cattattaat tatctcaaat aaccgtttat
    63841 tagaagttgt agataaaaag acaccgatgc ttgaagcttt ccgtgaagca gataatgttt
    63901 tacgacaagg tgtacaaggt atctctgatt tgatcacagc gccaggttac gttaaccttg
    63961 actttgctga cgtgaaaaca gtgatggaaa accaaggtac agcattgatg gggatcggtg
    64021 tggctagtgg agaagatcgc gtagtagaag caacgaaaaa agcaatctcc tctccattgc
    64081 ttgaaacatc tattgatgga gctgaacaag tacttcttaa catcacaggc ggtttggata
    64141 tgacattgtt cgaagcacaa gatgcttcag atatcgtagc aaatgcagca actggcgatg
    64201 taaatatcat tctaggtaca tctatcaatg aagaaatggg cgatgaaatc cgtgtgacgg
    64261 tcatcgcaac aggtatcgat gaatcaaaaa aggaacgcaa gtctagccga ccagctagac
    64321 aagcacaaat gcaatcacct gctcaaaaga ctgtattaga tatggatcaa gctaaaccaa
    64381 cttcttcaga agaagaaaac agttttggcg attgggatat cagacgtgaa caaaatgttc
    64441 gtcctagagt tgatgattcc aattttgaca atatcgaaaa aaaagaattt gatacattca
    64501 accgcgaaga aacaaaatct catggcgatg atgaattaaa tacgccaccg tttttccgtc
    64561 gtaaaaaata aaggagagga agagcacatg attgctgaca acttgcagaa aatcaagcaa
    64621 gaaattcagg attcgtgtgc tcttgttcat cgtgatccga aagaagttac attagtagct
    64681 gtaacaaaat ctgttgaatc cgctcaagct gaagaattgg ttagagctgg cgttatgaat
    64741 tgtgcagaaa accgagtaga taaattatta gaaaagaaac aagatttatt tgattttcct
    64801 gaaataaagt ggcatttaat tggtaattta cagcgcagaa aggtaaaatt gattgtaaat
    64861 gaaattgatt actttcatgc gttggacagt ttaagattag cagaagaaat ccagaagcgg
    64921 ttagagaaag aattatcctg ttttattgaa gtaaatgttt ctggtgagga atcaaaacat
    64981 ggaatttcac cagatgagct tttaccgttt gtggaatctt tagctgcctg cacaaaaatc
    65041 aaggttgttg ggttgatgac tatggcgcct aaagaagctt ctgatgagca aatccataaa
    65101 gtgtttggta cgctgaaaga attgcgtgat cttgttcaag caaaaggtta tgcccatgca
    65161 ccatgtagtg aattaagtat ggggatgagt caagactttc aaattgcgat tgaagaaggt
    65221 gcaacattta tccgtgtagg aacagcgcta ttcaaagacg aataaaggag gaacaaaaat
    65281 gccgctttta aacagaggag caattgctaa ttttttcgga ttagctgatg aggaagagta
    65341 cgaataccaa gattatcctg aaacaacaaa aaaggctgta cagccaacta aaaaaaatac
    65401 aacacagaat caatcaactc attctgtatc tgctgcgaat actcatgaaa aacaaaaaac
    65461 ggcgacttca cgtcctgtaa cgcatgaaag tattcagccg gctgaaaaga aaaaagtaat
    65521 tgaactacat caatcaccta caaaaactgt agcgaaagaa agaacagctt caagaacctc
    65581 tacacaacct aaagcaaatc ttgctggaaa aatcactgta atggaaccaa gagcttattc
    65641 tgaagctatg gcgattgcta aacgaatcat tgctggagaa gcaaccttag tgaattttca
    65701 tttagtagaa gaaaaacaag cgagaagaat cgttgatttt ctaacaggaa cagtttatgc
    65761 actagatgga gatatcaaac gtgttggaga tgagattttt ctttgtacac cgactgggat
    65821 ggagattgac agttcaaccg ctcaatcttt tgcagatgcg aatttgtttg atctgtaaga
    65881 ggaggaacta cgatttatac tattgcacta ttacttcatt tacttcaacg ggcagcctat
    65941 ttctatagca ttatcttgat ggtatatgca ttgctctctt ggtttccagg cgggtatcaa
    66001 tcagggctag gacgattatt agctaagatc tgcgaaccgt atatcagttt gttcgatcgt
    66061 ctgcctttga ggattggacc cttggatttc acaattttag gggcaatcct gatcttgaac
    66121 ttagccgtac aaggtttagc acagatcgtt atatggataa ctgtccattt agtttattga
    66181 ttgaagcaac aaaatcttta ttctcagaat agataggagg ggaaaatttt ggatgcaaat
    66241 gtataccagc actttcgggc agatgaacgt acatttatcg attcggtagg cgattggatt
    66301 gaacaggttc aaggacaata tgcaccctat ctgaccgaat ttcttgaccc aagacaatcc
    66361 tatattttag aaacactgat tcgacaaagc agtgatttgc gtttcatgtt ttatggcgga
    66421 tatgaacagg cagaaagaaa aagatgtttg attttccccg attattacga acctgtagag
    66481 gaagattttg aaacagcatt gtatgaaatc cattatccta gcaaatttgc cagcctaagt
    66541 catgggaaaa tccttggaac tttagtggga acggggatca aacgctctta ctttggcgat
    66601 atcatctcgg acggtgatcg ctggcaagta tttattgcaa atgaggtgga tcattttgtt
    66661 gctgcacaag taacaaagat tggaaaggtt gctgtacgct tggaaccaat caaatacaca
    66721 gaaatgatta tgccgaaaga tagctggaca caagaaagag gaacagttag ttccatgcga
    66781 ctagacagtg tgatctctga gatttataat atttccagac agcggtccaa gcagctgatc
    66841 gaagctggta aagtaaaagt gaactggaca gaaaatacaa gacctgattt tgtacttgaa
    66901 ctattagata ttatttcagt cagaggttat ggcagagtcc agatccaaga acttgagggg
    66961 aagacgaaaa aagaaaagta cagggtactg ttcggtgtat tacgtaaata aaataaaaag
    67021 gtggtttact catggcttta actccattag atatccaaaa taagacattc ccgacaaaaa
    67081 tgcggggata taatcaagac gaagtagatg atttcttaga tttagttgtt cgtgactatg
    67141 aggaattgac tcaaagaaat cgagaattag aaaaagcagt caaacattct gaagaaaaac
    67201 ttgagtactt caatgaatta aaagatgctt tgaaccaatc aatcatcgta gctcaagata
    67261 cggctgataa agtaaaaaca agtgcaagca aggaatccga agtgatcgtt acttctgcac
    67321 aaaacaaagc agatgagtta gttgcgaacg ctgaaaaacg tgcacatcaa ttaacaactg
    67381 atgcagaaga aaaagcaaga aaaatcttga cagatgcaac agaaaaagca agacagcttg
    67441 cgacagaaac tgaagatctt aagaaaaaaa cacgagtatt ccatcaacgt atcagcttga
    67501 tgcttgagtc tcaattagaa caagtgaaaa gtccggaatg ggatgaaatt ttacaaccat
    67561 tctccagcta cgtgactgac agccatgaag tgatcaaaga agttttagca aaacagcttg
    67621 acaatgaaaa tgatactgat gtaaactcag acacaggagt catagaagca cctatgacgg
    67681 catttgatac acaggctatt gatatctcga tcgtgcctgg tgaaaatgaa aacgagtaga
    67741 acagaaaagc actttgttat tcttaaagcg agccgatgag agtggaagtt cggtaagaca
    67801 ctgcatggtg aaagatcctc tacttgagac ctgcttttcc gaaattagag taagaagcag
    67861 cggctgacct cgttattggt cacagagagt ttgcactaga tagatgcaac taaatttggg
    67921 tggtaccacg gcatgttcgt cccttgcggc tgaacatgct tttttgtgtc cggaaaacaa
    67981 ataaaggagt gtatggttga atgaaaatga aagaaacctt gcaattagga aaaacaaaat
    68041 tccctatgcg tggtaatttg ccaaaccgag aaggcgagtg gcaaaaagaa tgggaagaaa
    68101 atcgaatcta ccaaaaaaga caagagttga acgaaggaaa acctagcttt gttcttcatg
    68161 atggacctcc atatgccaat ggtaatatcc atttaggaca ttcattgaat aaaatcagta
    68221 aagacattat cattcgttca aaatcaatgt ctggctatcg tgcaccatat gttccaggat
    68281 gggatacaca tggattgccg attgaacaag tattggctaa taaaggcgtg aaacgtaaag
    68341 aaatgtccat ggcagaatac ttggaaaaat gtcgtgaata tgcactttcc caagtagata
    68401 agcaacgagc agatttcaaa cgcctaggag ttgcaggaga ttgggaacat ccttatgtta
    68461 cattagatcc ttcttatgaa gctgcacaag tacgcgtatt tggtaaaatg gctgaaaaaa
    68521 gctatattta caaaggattg aaaccaattt actggtctcc gtcaagtgag tcttctttag
    68581 cggaagctga aattgaatat aaagatgtaa aatctccatc tatttttgta gctttcaatg
    68641 tcaaagacgg caaagatatt cttgatgaag atacagcttt tgtcatttgg acgacaacac
    68701 catggacatt gccagcaaac caaggtattg ctgtaaatcc aaaatttacg tatgtattgg
    68761 tggaagccga tggccgtaag tttgtcgtag cgaaagattt gctagaaaca gtccaatcag
    68821 aaatcggttg ggaaaatgta acagttctaa aagaatttgc tggacaagaa atggaatata
    68881 tgactgcaag tcatccattc tatgaacgtg aatcacttgt gattttaggc gatcatgtta
    68941 ctttagacgc tggtactgga ttagtccata ctgctccagg acatggggaa gatgactata
    69001 tcgctggtag caaatataaa ctatctgtag tgtcacctgt agactcaaaa ggattgttta
    69061 cagaagaagc acctggattt gaaggtatct tttatgacaa agcaaatcct atgatcactg
    69121 atctattaaa agaaaaagga gctttgctga agctagattt ctttactcat agttatcctc
    69181 acgattggcg gacgaaaaag cctgtgatct atcgggcaac tccacaatgg tttgcatcta
    69241 tcgataaatt ccgtcagaat attttggatg aagtagaaaa agtagagtgg gttatcccat
    69301 ggggtaaaac acgtttgtat aatatgatcc gtgaccgcgg cgattgggta atttcccgtc
    69361 agcgtgcatg gggagtacca cttccgattt tctatgctga aaatggagaa gcaatcatca
    69421 caccagaaac aatcgaacat gtggcaaaat tatttgctga acatggatca attatctggt
    69481 ttgaaaaaga agcgaaagaa cttcttcctg aaggatttac ccacccaggt tctcctaatg
    69541 gcgaatttac aaaagaaaaa gatatcatgg atgtctggtt tgattctggt tcttctcatg
    69601 aagctgtttt acgtcagcga ccagaattat cattcccagc agatatgtat ttagaaggat
    69661 cagaccaata tcgtggctgg ttcaactcaa gtatcacgac tagtgtggct atcaatggtg
    69721 tagcaccata caaatcagtt atttctcaag gatttgcttt agatggtgaa ggccgtaaga
    69781 tgagtaaatc tttaggaaac atcattgcac cagaaaaagt gatcaaacaa tttggtgcag
    69841 atatccttcg cttatgggta tctagtgtag attatgaagc agatgttcgt gtttctatgg
    69901 atatcttaag tcaagtggca gaagtatatc gtaaaatcag aaatacgatg cgtttcttat
    69961 tagcgaatac agaagatttc gatcctaaaa aagatactgt ttcgtacaat gatttacgtt
    70021 ctgtagacaa atatatgacc gttcgattga accaagtaat caaagaaatc cgagaagaag
    70081 ggtacgacaa atataacttc atgcatattt accgtacagt tatgaacttc ttgacggttg
    70141 atctatcgtc attctacctg gattttgcta aagatgtagt ttatattgaa gcagaagatg
    70201 attatcaacg tcgttgcatg caaactgttt tctatcaaac agctgtagct ttgacaaaat
    70261 tattgactcc tatcattccg catacagcag aagaaatctg gtcattcctg aaagaagaag
    70321 aggagtacgt tcagttaagc gagtttcctg gttatgaaga gtttgcaaac caagaagaat
    70381 tgatggatac ctggactgct ttcatggact tccgtgataa tgtcttaaaa gcattggaag
    70441 aagcaagaaa cagcaaattg attggtaaat ctttggaagc aaaactaact gtttatccaa
    70501 aacaacaagt tcgtgaaatg ttaaaagctt tggatgcaga tattgcacaa ttattgatcg
    70561 tttcaccaga ctactttgaa gttatggcag cagatgaaca agtgccagat aacgctatgg
    70621 tatttgatga tgttgctatt acagtggaaa aagcagacgg ggaaacttgc gatcgctgtc
    70681 gccaagttcg taaagatgta ggagtagatg aaaaacttcc tcatctatgc ggtcgttgtg
    70741 caaaaatcgt tgaagacttc tatcctgaag ctgtagctga aggattcgaa gaaaagtaaa
    70801 agggaaaagg gggtgtgaca tgttctttgt cacaccccct tttgttatca atcgtttaat
    70861 tttccacgtt cacgatacca gttatctggt tgccagatcc attcgaatcc gtctttttca
    70921 agtagttcga aagctgcttt aggtcccatt gatccagctt tgtagttggg aaaatccggt
    70981 tgtgtttggt cccaagcttt tcgaatgaca tccacgatat gccaagattg agcgacttct
    71041 tcccaatgag agaagttcgt tccatcacca ttcaacgcat ctaatagtaa tttttcgtaa
    71101 gcttctgggc tattttcaac catttctgca ctatttctaa attccaattt gattggttcc
    71161 gtttcaaatc cttgccctac ttctttccca ttcaaggata aagaaaatcc ttcagttggc
    71221 tgaatataga tcgttagaac attaggtgga agtgtcgtat cgtcacatgg ttcatcgaca
    71281 gatgttttga atacattaac aggaacttgt ttgaatacga tgttgatccg agtccctttt
    71341 tcagtcaaac gtttgcctgt acgtacatag aaaggaacac ctgaccaacg gaagttatcg
    71401 atagtgaatt tgcctgcgac gaatgtttca gtctctgatt gagcatccac tttgtcttct
    71461 tcgcgatagc ccttgaattg tacaccatcc aattcacctt gagcatattg cccgcgaacg
    71521 aagttttcta acacttcttc ttcgttataa atgcggatag ctttcaatgc tttgatcttt
    71581 tctgtacgga tttctttttc ggaaaatgct actggcggtt ccattgcaag taatgctaca
    71641 acctgtaaaa tatgattttg caccatgtct ttaagtgcgc cactatgatc gtagtagccc
    71701 ccgcgatctt ctacaccgag gttttcgcca aaagtaattt ggatattgtc gatatagcga
    71761 ttgttccatt gagcctcaaa aatattattg gcaaaacgga tagctgagat gttttggatc
    71821 atttcttttc ctaaataatg atcaatcctg aaaatatctt gttctgggaa tacttctctg
    71881 atttgctggt tcaattcaaa agcagactgg taatcagaac cgaacggttt ttctatgatc
    71941 aaacgattga agccattttt tgtcataata ttttgtgatt tcaaatgaga aacgatcgtt
    72001 ccaaaaaatt gaggtgccat agccaaataa tagacacggt taccgtttaa ttgatagtgt
    72061 ccatctaatc ggtcagacaa ttcttttaat gtctgataat gcgttgaatc atttacatca
    72121 tgggattgat agtaaaaatg gcttgcaaag gtagttgctt cttcatctga aggattcaat
    72181 gcacggattg tttctttgac aacttcacgg tagtgctcat cgctccaggg acggcgagcg
    72241 gttccgatta cagcaaaatg ctcgcctaaa tttccttttc tgtaaaggcg gaacaaagac
    72301 gggtacaatt tacgctgggc taggtcacct gtaccgccga atatcgtaaa caatacattt
    72361 ttttcattag acatgtggat acactccttt atattttatc gacaaaaatc gtgctggccg
    72421 ccttaaagct gacggggatt ttctttctat cattttggat agtgatcggt ccttcataag
    72481 ctgcgatgtc aacgatctca tattcttcgt tgatattcag gtcaatagtg actaagtaat
    72541 ccaacaattc tttttcatca agcactcgtg cgatacgcac ttttgtaccg acaggatagg
    72601 actccaatgt ttgtcggcgt tcttcatgga caacttcctc ttttttagga atcgatcctc
    72661 catgaggaca atgttcagga tgattcaaat agttttctaa atgatctgca agatgttccg
    72721 aagtcacatg ttccaatact tcagcatcat catggacttc attccagcta tagtctaaat
    72781 gttcaactaa aaaaacttcc cataagcgat gtttgcgaat cagactgcta gctttttgca
    72841 gtccgcttgc agtcaattgt acaccttgat aaggggaatg ttctacaagc tcttctttca
    72901 caagtttaga aatcatttca ctgacagatg cagctgagac atctagacta gatacgattt
    72961 gtttattgtt gactttcgtt gtatctccac ctagttctaa aatgattttc aaataatctt
    73021 ctcgatttgg tgtcatattc gatcatcctt tcatggtaaa aaaccatcat tagtaagtgt
    73081 aacaaaaaaa acgttaattg actatttttc taaataaaaa acaaaggatt tttagacgtt
    73141 tttacaacaa aaaacgaaag atgatagaga agactcattc tttcgtttat aaaggatata
    73201 tatatacatt gggagggatc tatttttcag ataacaactt atatgaagtg tctgcagatt
    73261 cgtcataaag agtttgttcg ggataagaaa agataagata aaaaccatac tgatcacgta
    73321 cgactaaacg atattcatct atttctacca cagatgtgcc aagagactga ccgttgatca
    73381 aaaacgtgta atcagatgta atctgtaatt gttgtttttg ctggctatca ctaaagaacc
    73441 atgtaccttg atactttgag agtccttctg acttttccgc ttgttttttc tttttcaagt
    73501 aaataaaact tgagagaacg gtaatgagtg aaccaagaaa atagatcatt ttttttatca
    73561 ccaaatcact cctttatgag aaaataatcg catagacata ttctttcttc tttatttcat
    73621 tgtaccgaat aaaagctaaa atttctctaa gactttcgac tggttttttt actgtttttc
    73681 tacaaattat gataggatac atagtaggaa gaaaggtgac ataatttgaa gtatcagcaa
    73741 gtggaaatag ctttttttat tgaccgcccg aatcggttta tagcacattg tatgaaaaaa
    73801 gacggagaaa taattattgc gcatgtcaaa aatacaggta gaggaaaaga ggtcctgata
    73861 ccaggcgctg aagtggctat tgtatttgct cctggaccta aacggaaaac cgcctatgat
    73921 ctgattgctg taaaaaagaa gggtgactgg tttaatatcg atagtcaatt gcctaatcgg
    73981 ctggcaattg atggtatttt agacggcacg atccttttac caggattaac tggtccattt
    74041 acggtataca agcgtgaagt aacttatctt cactccaaat ttgatattta tttagagacg
    74101 gtggtcggac aaaaagcatt tgttgaagtc aaaggtatga cacttgaaaa taaagcgatt
    74161 ggtgcttttc ctgatgcgcc cacactcaga ggattgaaac atataggaga attaacgtat
    74221 gccgcacaag atggttatgc cgcttatgtc ttgtttattg ctcagttcga acatcttcat
    74281 ctggcaacga tccatgaaga aatgcaacca gcactagctg atatggttcg acatgcgcag
    74341 caaagcggag ttcaaatcct cgcctataat tgtcaagtat cggcagatga ggtaactgtc
    74401 aagcaggcca ttccatttga tgtagatatc ccttttgaag atcctataca atagaaagaa
    74461 ggtaaaataa tgatcaactt aggtattatc ggaacaaatt ggattactca tcaatttgtc
    74521 caagcagctt taagcacaaa aaaatatgaa ttgacagcgg tatattctag acatttggaa
    74581 aaagcacagg aatttggttc tcattatgaa ggggatatcg aattcgcaac agatttgaag
    74641 acttttttca atattactca tatggacacc atttatattg cttctccgaa tagtcttcac
    74701 tttagtcaag ctaagcaagc aattttggca ggaaaaaatg tgatagttga aaagccagct
    74761 ttttcgacgc caaaagaaat ggatgaaatc atccatttgg caaatgaaca caatgtgtat
    74821 ttttttgaag cagcaagaaa tatccatgaa tcaggtttta aaaagattgc cgattactta
    74881 ccattaaaag acgagataat cggtgcaaat ttcagctata tgaaatattc ttcgcgctat
    74941 gaccaagtat tagatggaga agaaccgaat atcttctcga ctcatttctc aggtggtgca
    75001 ttgatggatt taggtgttta ccttgtatat gcagctgttg cttggtttgg aatgccaaaa
    75061 gaagtccatt atttcccaag aaagatttct actggtgtag atggtcttgg atgggggatc
    75121 ttacgttatg agaattttga tgtatcgatc cagccaggta aaatcggtga ttcttattta
    75181 ccgtcagaga tttattttga ctcaggaacg ctagtgatga atggagtcaa tgcaattgaa
    75241 caagcacaat ttcatgatcg cgcgcataaa gaaatcattg atttggcggt aacagctgca
    75301 gaaaatccaa tggcagatga agcagaggat tttgccaatg tcatggctca tccgaaagat
    75361 ccagcttggg gattgttgta tgaagagtgg atcgagctag ctagaaatgt gaaccaagtg
    75421 atttatgatt taagaaaaaa tggcggcatc aaattcgatg cagataatga ggaagatttt
    75481 taatgaacga atttgtacaa gtatttcccg aaaattggca gaaaaaatat gaggataaag
    75541 ggtttatctc accttctctt attcaacgag cagtttttca gccactaagt aataaacaaa
    75601 gtatagtagc ggtttctcct acaggttcag gtaaaacact ggcttatctt tggcctctac
    75661 tactaaacgt ggaaccaggt gaagcaagtg cgttggtcat ttttgcttct tctcaagaac
    75721 tagctattca agtagcagat gttgcacgtg aatggggaaa agacaaagag ttgaaagtcc
    75781 aatctttggt gggcggagcc aacgtcaaac gtcagattga gggtttgaag gaaaaaccag
    75841 aaatcttgat tggtacacca ggaagaatat tggaattgat gaaagcaaaa aaaataaaag
    75901 cacatcaagt gaaaacaatg gtatttgatg aagcagacca gctatttgac gctgggaaca
    75961 gccaaatcat tgatcaaatt cttcatcaag ctccaacaga gtatcagcta gctttttttt
    76021 cagcgacagc agatcgttcc cttgaaagca ttgaaaaaat cactgggaaa acgtttgaga
    76081 caattgacgt gacagcagag gacgattctc gaaaaggact gagacattac tttttacgtg
    76141 taccgatacg aaagaaagat gactacttga gacgtctcac gcatatagaa gattttcatg
    76201 gtctgatttt ctttaatcaa ctgactgaat taggcgtaat ggaagaaaaa ttgctgtata
    76261 gaggtgtacc ggtaggaagt ctggcctctg atcagaacaa gctactccga aaagcagcgc
    76321 tagaacaatt caaaaagaaa atggtcagag cacttttgac cacagatgtg gcggctagag
    76381 gtttagatat tacaggtctt ccttatgtag tgaatgcaga agttccgtta agtgaagaag
    76441 cttatttgca tcgttcggga agaactggtc gaatgggtaa tgaaggaata gtaattacac
    76501 tcgtacaaga taataatcta agagatttaa aacggctttt acgtccatca aatataacac
    76561 ttgaagagat ttttttatac ggaggtaagc tgcaaactga gcagccaacc aaagaagatg
    76621 cagctcctgc agtaaataaa aagtatgcga aaactttttc tggaaaggag cagaacccag
    76681 aatataacaa agaaaaaata agaaaaaaag ttaaaaataa atcaaaaaaa gagagaaata
    76741 aaggagcaag gcgcaaataa gcgccttttt atgctatgat tatgaaaacg ggaacaaaat
    76801 tggttgccag aggaggggtt atgtgaaaga acgtcaagaa gagatcttgc agctattgac
    76861 agaaaaccaa caaggattga cagcaagtga tgtagctgag cgcttaacta tcgatcgaag
    76921 caatgcaagc cgatatttaa gtgaactata caaggcccat catattgtaa aaaccgctgg
    76981 ccgaccagtc gtttactctt tgccaacgga aaagtcaaaa tctgatgaag tgcatgtcga
    77041 ctcttctacg caagtgactt ttgaaacact cgttggagaa aatgattctt taaaagtcag
    77101 catacagcag gcaaaagctg cgattcttta tccaccgcgg gggttgcata cgattatttt
    77161 tggagaaact ggtacaggga agtcgatgtt tgctgaatgt atgtatcatt ttgcaatcga
    77221 ttcagagatg ctttctgcag atgcgccatt tgtttctttc aattgtgcgg attatgctca
    77281 aaatccgcaa ctgctctttg gacacatctt tgggatcaaa aaaggggctt acacaggagc
    77341 agctcaagat agtcccggtc taatagccaa agcagacggc ggtatattgt ttttagatga
    77401 gatccaccgt ttaccgccgg aagggcagga aatgctgttt actttcattg ataaaggtat
    77461 ttaccgtccg cttggagaaa gtgcacaagt acatgaagca tctgttcaga tcattggggc
    77521 gacgactgaa tcttcagaaa gtttcttatc tacgttcaat cgacggattc ctatggcaat
    77581 caccttgccg aatcttgctt cacgttcact ggatgagcgt tatgaaatca tctctctttt
    77641 tatcaaacaa gaagcgaatc gtttgaatca acgtatcgat atcgaaaaag aagcgattct
    77701 tgccttcatg ctttatgatg cggaaggaaa tatcggtcaa gtgaaacgag acttgaaact
    77761 agtctgtgca aaatcttttt tacattaccg tactcatcat gagaaaaagc taatcattcg
    77821 aaaagaagaa ctttcccttc aagtacaaaa aggattactg aaaatcaagg aaataccgga
    77881 acgtctcgac cgattcatgg acagcaaaag tcagtatttg acatttgaac caggatttgc
    77941 tgatgttgtc tggtcacaag atccagaacg aaacatgcag gtctataacg atattgagga
    78001 aaaagtcact tctctttccg aaaccggtgt ggagaacatt gatctagaga ccctcatttc
    78061 aaaagatgtg gatgcttatt tccagacata tgtcaaagaa ttgactaaaa gttcgattcc
    78121 caaagatctt ttgccagatg aaatctggcg gttaaccaat caattgtatg atgtggctga
    78181 aaaacggtta gaccgtattt ataatgaaaa agctcgtttt gcttttgctt tgcatctgca
    78241 aagtacattg gatcgtgtga gagaaggtca tatgatcgtc cacccagatt tgaataacgt
    78301 acggaaaaat tttaagaggg aattccaggt agcaatcgat ctttcaacga tcattgaaga
    78361 agaagaacaa gttgagattc cttttgatga aatcggcttt attagtatgt ttctttctat
    78421 caatctagga gaaagtgagc ctgttaaaga aaacaaagta gatgttctca tattgatgca
    78481 cggcagacag actgcttcaa gcatgttgga gatggcacaa gaactattag gaacaaaagt
    78541 agggaaagct tttaatatgc cactggttat ggaagttcaa acaatgtatg aagaagtgtt
    78601 acaatatgtc aaaaactatc aagagcattt gacgaatggc ctactcttgt taacagatat
    78661 gggatcatta aacaccttca gtgatttgat ttatgaagag actggcattc ggacgaaagc
    78721 tatcacgatg acaagtacca tgattgtgat agaagcgata cggatggcaa gtgttggaag
    78781 aagcttagaa gatatttatc aaaatatcca gctttccttt gaatcgatcg tacgtgatca
    78841 gttcaaagcg gaaaagtctg aaactttaca gcgtaaaaaa gccgtaatcg tgacatgctt
    78901 tactggtgaa ggagtagctg ccaaattata tcagcgtatt atgccagtga ttaatcaaaa
    78961 taaggtagaa ctgatccaga tgcagttttt agaacgtgaa tcattcaaaa aacacatcga
    79021 tgccttattg gaagaatatg agatcaaagc aattgcggga acagttgatg ttgattatca
    79081 aaatatccca tttttttcag cctatgacgt ttttgatgat gaaaaactaa atattttaaa
    79141 gcgtatagct gatgatgaga tcccgacagc taaaattgtc gattcacttg ctggatcatt
    79201 aagcgatgtc ttttctattg atgaactgat ccgttcattg caaaagacag ttcagcagat
    79261 ccagaccgat ttgtcgatta tcgtggaacc tggagtagat actggaatcg ttatccattt
    79321 agccttcatg ttagacggat tgatcaaaca agaaagccat cggcaatttg agaaactgtc
    79381 tattttctca aaaatttatc gtttggaaat ggatatcgtt cgggcaaact tgatggcact
    79441 agaacgaaaa tatcaggtaa aaattccaga agatgatatc gcatttctta cacaaatgtt
    79501 tcttgaaaat aaaataaaaa aatgaacaca ctaatcatac tgtttacaca ctaaacatct
    79561 gtgtgcgcac tataaaaaag agctaaaaag catgaaaacg ctatttcagc tctttttttt
    79621 attggcatgc ttcttgcgtt atataaaagt gtaaaaaaat aaaaggagtg ttaaaaatgg
    79681 caaaaaaaac aatcatgtta gtttgttcag cagggatgag tacgagttta ttggtcacaa
    79741 aaatgcaaaa agcagcagaa gaaaaaggga tggaagccga tatttttgcg gtctctgcct
    79801 cagatgcaga taataattta gaatctaaga atgtcgatgt attattatta ggtcctcaag
    79861 tacgtttcat gaaagctcaa tttgaacaaa aacttgcgcc taaaggtatt ccattagatg
    79921 tcatcaatat gcaagactat ggcatgatga acggagaaaa agttcttgca caagcagaaa
    79981 atctaatgaa ataaatcaag tatgcagttg ggggtataac aacgtggaag atcaacaaaa
    80041 tctagaagcc atcatggggt taatcatgtt tggcggtaat gcaaagagcg atgcaatgga
    80101 agcgattgcg gctgctaaaa tcggtgattt tgagttagcg gataggaaaa tcgctgatgc
    80161 agaagaatca cttatacaag cgcatcatgc acaaacagac atgttgacac aagaagcaca
    80221 aggaaatcat atgcaagtga cattattgac tgttcacagt caagatcact taatgacatc
    80281 tattgcgttt actgatttag caaaagaaat catcgaactt tatcgtcgcg tatacagcga
    80341 ataaatacaa cttctttttt gaacggaaga agaaaaattt ttgaacggat tttttatttt
    80401 gttataagga gaactctctt tatataaaaa acttatagga ggaagtaaaa aatgaacgga
    80461 ctatcaagtt ggatggagaa atacatcctg ccggttgccg caaaaatcgg agcgcaaaaa
    80521 catttagttg ctttgcgtga tgcttttatc ggcacactgc ccgcaacaat ggcgggatca
    80581 gtcgctgtaa tgatcaatgc aattattcgt gatttaccgc aacagtttaa cagtacctat
    80641 gctgacagtt tagcagcaga caaaggaatc tttgccgtat tgaatgtcat catcggaatc
    80701 aatggttttg tctggaacgg tacactagca atcgccggat tgatctttgc cttttcttgg
    80761 gggtataatc ttgcccgagc ttatggagta aatgatctag ctggggggat cgttggttta
    80821 gctaccttga ttcaaggtat ttcctttggt ccagcattat cagcagcatt agatgtgaat
    80881 gttccttcaa atgtcgcaga tgcaatcaat agttctgaga ttggtgcaac gattgcagat
    80941 ggcacactgt cagttggatt atggggttgg ctaaaactag atcatttgaa tggaaacgct
    81001 tattttacag ttatgatcat gggagctatt tcagtcatta ttttttgtaa attgatgctt
    81061 gccaacatta cgatcaaaat gcctgattca gtaccaccag cagtatctaa agcatttgca
    81121 gccattttac cagcgacgat cgctttatac gtcattgcta ttatcaatta tatcgtaggt
    81181 cgtgtagctg atgggcaact gatcattgat ttggtgcaaa aatatattgc agaaccattc
    81241 ctaggattat ctcaagggtt gggagcagta ttgatcgtca cagtatttgt tcaagtattc
    81301 tggttctttg gtattcatgg accaaatgta ttggcaccag tgctagaggg aatctgggga
    81361 caagcacaac taatcaatat tgatattttc caaaaaggtt ataacggaaa aactggtaca
    81421 ccagccgtgt tagatgcaat cgaagatgga aaagcttata tgtgggtccg cggatcgttc
    81481 gatgcttttg catggtttgg cggatcaggc ggaacgatcg tcttactgat agctatcttg
    81541 attttctcta aacgtgcaga ttatctaaca gtagctaaat tatccattgg gcctggtatc
    81601 ttcaatatca acgaaccagt gatgtttggt ctgccaatcg tattgaatgc aatcatgttt
    81661 atcccattct tgattgctcc agtagtagca acagcaattg gatggacagc tacttatctt
    81721 ggcctagtcg ctccggtatc gcagcaagtc acatgggtag taccgccgtt cttattgtca
    81781 ttcttagcaa caggagcgga ttggcgggca ccgatcgtaa cattagtatg tatggtcgtg
    81841 actttcttga tttgggcacc atttgtcatc tctgcaaaca aaatggaccc tgccgcaggc
    81901 gaacaacaat aagatgaacg tgaggagcgg gacgctttaa gtttcgttcc tcataatgaa
    81961 ttttcgagga ggaactgaaa tgattacaat tgccagtgca atgcaacaag atgaaatcaa
    82021 agaattgtta gaaggataca atgaagaagg aatgactttt acatttaaag aaaaacaagg
    82081 aatcaagctg ttctttgaaa caagtgcaga agatccggaa gttgcggcta aaaaagcaaa
    82141 ggaactaatc aaagcacagc cttggggaac agtcctttat tttcaatcaa cagctgttta
    82201 gaaaatggtt taaaaagata ggatggttga gatgataaaa aacggtttat ttttatgtag
    82261 tattggttct ttgatcgtgt tgtatagttt gaatccacat tcgcaaaggt atgatttgta
    82321 tagtatggtc acaggtcttt ttctaacagg attaggaatc tatttcttca tgaaggggaa
    82381 aaaaagagaa gaagcaaagg agaaaaataa ctaatggaaa tcacgaaaaa attaaatatt
    82441 ccagcatcgt ttttttacga taaagttatg gactctgtcc ttttcgatgt acgtaaagcg
    82501 accggcaaat cagtaactag aaaacagctg aaaaatttgg agtacgtcaa acaattctcg
    82561 caaaataacc gggctcgcat aaaaatcgaa gaagtcattg aaaaccagtc ttataagttt
    82621 cgtacatcga caacgaagaa tgaattcgtc gttcattatc aaatcaaacc attggacgat
    82681 tcgacctgtg aggttcatta cacagaaaaa atggagtctt atggcatgct tcaaaagttg
    82741 aatgatatgc ttttaggaac aatcttgatg tattttaaac ggagacgttt caaaaaaatg
    82801 ctagatatga tcgaagcaac gtattaaatc aatgaaacat ggtactattt agttattgaa
    82861 aaatgaagta agctagaagg aatttttcat aggaagatag atctttcctg cgaatcctca
    82921 ctagcttttt tgtaggaagg ggcagcaaaa tgacaaacaa agtaagagag ctaggtgtat
    82981 cttcgattga ggaaatgttt gatttagcca cttatgcatt taatggggca gatacacctg
    83041 aaaggcgaga acgttttcgt acacttgcgg agaattcttg gaattacgga ttttttgatg
    83101 aggaggatcg gctaacaagt caagtcatgg cgaccccttt tccagtgaat ttttacggac
    83161 aagagtacct aatggccggc attggctatg ttgcttctta tccagaagca aggggacaag
    83221 gcgggatcaa tcagatcatg gaaaagatcc ttgaagattg ccgtgatcgt aaagtaagct
    83281 tatcttatct ggcgccattc tcctatccct tctatcggcg ctatggctat gaacaatcat
    83341 ttgataaaat cagttatcaa ctaaacagtc gtgatgtgcc gtttatcaaa aaaaaatctg
    83401 gaaaaataaa gcgtatggat tttgaagatg caaaagctgc aatcagaaga atttatgaac
    83461 agatgccgga aaaccaacga gctggtctga agcgcgaaga ctggtggtat acgtataaat
    83521 tcaagcaaaa aggcaattac cagtttgctt tgcattttga tgataatgag gaagcaacgg
    83581 gatatatcgt ttatcagctt gcaacgtctt cctttattat tgcggagtgg ggatttttgg
    83641 atcatgatgc tttttgcagc cttgttcgct tcgtaagttc tcacaatggt gcttttgaaa
    83701 catttgaata ttcatgcggc tacggcggta atgatcaaaa ttatctatta gaaaatccat
    83761 ttgcttctgt aatgatcaca ccttatatga tggcgaggat cgtagatatt tctttgtttt
    83821 tggaaaatta tccatttaaa aagagacaag ctgcatttgc cctacaaata gaagaagatc
    83881 attatgcgaa atggaatgaa ggaatcgtgg aagtaacaat cgaaaatgga aaaaatcatc
    83941 tctcaaaagt agaacaaaca aaactcccaa tcgttcgagg aagtatccaa catatcacgc
    84001 agctattatt agggtatcgt aaagtggaag agttggtatt ccaagaaaga atacaggtga
    84061 caaaagaata tgaagaaacg ttaagctcaa tcttgccaca gcaacagcca attcttaatg
    84121 actatttttg ataaaaaacg ggtgatgaca atatttttgt caccaccctt ttgtttttca
    84181 tttggcattt gaaggaaaat gttaaagtaa atcctctttt ttcgtaaatt tgaatttttt
    84241 gttttctttt gttttagggt tttctttttt gtggtcttgg attgcttctt tcgtaatctt
    84301 ttcccgattt tttttagatg aatctaagcg ttctgcgtat actttttctt ttggcttatc
    84361 attcattgga aaggacctcc ctacattatt tcattctacc tctagtttat catctgttaa
    84421 ggactagtgg aaacgttttg cctaacttat aagctgattt ttttagcaga taagcttgca
    84481 agtaaaaaac aaacaagcta caattgattt attgaaattg ttcctgtagc tcagtaggat
    84541 agagcaatcg cctcctaagc gataggtcgc tggttcaatt ccagtcagga acgtataaat
    84601 aacccctgta tcctttgcgg tacaggggtt tgttttgtat ttgtgccaaa aatgtgccaa
    84661 actagttatc atttttatat aaactatcga acacagtatt gattttttct ttatcctgat
    84721 cttcaagctc tcgaacaata tgaagataag tagacattgt agtttctaaa ctgctatgtc
    84781 ctaaacgttt cgatacgcta agtatattta ctccttgata aagtaaaata gatgcatgtg
    84841 tatgccttag tccatgcaaa gtaaattgct tttcaatccc taattctttt aattttttgc
    84901 gcaaatattt gctgacggcg tttgatgaaa ctaatccatt ttttaagttg aaaaaaacaa
    84961 aattatgagg gtttttgatt tcaaaattct cgaataattc tttttgattg attttaaact
    85021 tttttaagag atcaatcgta tgtttatcaa tggaaatttt cctatttgaa gtttcgtttt
    85081 ttgtttttcc ccattcattt aatttataat tccatgtttt attaatagtg atgatttgat
    85141 cttcgaaatc gatatcttcc catgttaatc ctagaagttc agcaaatcgc attccagtgg
    85201 caccagcaac taacacgagc ataggagaag agtactgcgc agaaaggttt tcttctacga
    85261 gtttcattaa agatttaaat tgatcataat ctaaatattt atcttctttt ggcttcaatg
    85321 aatcttttcc tttgattact gcttttctag ttggatcaaa cggaattaat ccttcttcta
    85381 cggcatcttt caacgatgct ctaatatggt tattaaactt aataacggtg gattttacat
    85441 ggtctttcgc atacttattt aaaaagcgtt gatatccaac tctatctaaa tcagaaatca
    85501 ataccgctgg catatatttc tttatgttca ttaacgtatc ttcgtatttt ctataagtga
    85561 taggagatac tgttccttct ttataaagtt gcatccaatc ctcaaagtaa tctgataata
    85621 atagattttt gcgatcccct ttaaggcctt tgttcaagtt atattctaat tcgttggcgg
    85681 catcttttgc ttcgcctttt gtcttaaatc ctgattttct tatcttcgtg tattttccgt
    85741 catctttttt gtatgaaatt tcgtattgcc aactatttcc acgtttgact aatcttgcca
    85801 taattgaatc tactctcttt ctctgataca ataggcacta taaagaagcc tactgtatag
    85861 gtttgttttt cttagaacac gcttgctttg gacggtgggc gtgtttttta tttattatac
    85921 agttgcttta aaaatagctg ctttttcaaa tgatactaaa ggagagaagt ggatttctat
    85981 ttctcccttt tggtttaacg tgaaatgagc agttacatcc atttgttttc ctggagcaac
    86041 agatcccatt gtattttcgt tggcatatgt ctctgatttt ttgtcatctg gtccatatac
    86101 ttccacatct gtacctacag ggatatctga atcgccatca ttttttacgg tataagtaat
    86161 ttttactact tgtgcaggtt ggttttcttc aaattgattt ctttcatcag ttagttctac
    86221 actatttagt gtatattcag catcaccaac ttttacagtg tcaccaatct tatagaaggt
    86281 atcgcttttt tcttctttag aagatgaagc agaggttgaa gatttagtta ctttttcgcc
    86341 accattatca cttgctttat tactatctga tccaccattt aaagcagaac caataattat
    86401 aattaaaatt actgctaata cccaaaacca tacttttttg taaaaaggtt tactaacttt
    86461 atacattttt ccgtcttgac ccataacttt ttttgccatt taaatattcc tcacttcttg
    86521 ttataatata tttgcgatct cagaaatgag gtatgagtcc gtgttgcagc acgggctttt
    86581 tttactgtgc ataagagtat tttttcttga aatatgactg gcaaacatta aaacattctg
    86641 ttcttaactt attattgata gcatagaatt ccataaaatt ttccaatttg aactgagatt
    86701 catctgttaa ttcattctca ataaagatat taagtagaat cataattgca attttatcag
    86761 cttcagtttc gaattttgaa tgaaaagttg tagagttatc gtacagtact gaatattcaa
    86821 aatgtgaagc aatgaaatga ccgagctcgt gggctaaatg aaaagcttca gaactatctt
    86881 cgtgtagttt ttcgtttaaa aatactattc ttggttttgg ataataaaaa cctggttctt
    86941 ccatttccat atagattaac tttaaattat actcactcag catttctttc aactttaaat
    87001 acatacaacc catcactcca actattcatt ttcctctaaa gctttagcaa ttgcaatcgc
    87061 tttacgcatt gtctccttag atatttcttt tccatcaaaa gaaaaaacag tatcgtcttc
    87121 tgataaatcc acatgtttag gggtttctct ttcttctcta cctagaaggt agtctacaga
    87181 gactccaaag taatcagcta accgagctaa ctcaatagaa ttaggagttt gtcttttcca
    87241 acttcctaaa tatccattcg aatacccgaa attcatttcg agctgtctaa tggataatcc
    87301 tttttctttt gctaactcct ttattatttc gtaagtattc attgataaat caacctttct
    87361 gaatgcttac aaaaaaagtt tagataaata atgtaaaaat agttgactta tatacattat
    87421 taatctatac tatgttttgt aaacaagttt aacaactaaa aagacaacaa aaaatactat
    87481 tgattaataa atgccaaccg ccaagaaagc tttttaaatc aaagtttaga tgtcttattt
    87541 aactatgcat ttagtataga ttattaatct aataaagtca acgcagtttt ttaaaaagtt
    87601 gttaaatttg tttacgaata taaaagaaag gagagaagaa tatggaaaaa acagtctcgg
    87661 caaaaatcga agatttgaaa ttagacatac tgaaacaagc aaaagtggcg atggaacacg
    87721 cggtagataa agaagactct gccatggttg cagccatagc agagatttta gctcacgttt
    87781 agtcatcgtt tttacggtct tctggaagct gaccatagat aacagcataa tgaatatcta
    87841 aataagcttg aacaatttct tttggcgaaa ttgattcgcc tttagtagat acttgtgatt
    87901 cgtgatttag ccatgcaaca actaaatccg cagcgatttc aaacggcgtt acactttgtg
    87961 tcagttgcca taaagaattt cacaatatgt atggtcgtgg taataatacc aaagagcaat
    88021 ttgaggaatt tatggaaatt aaaaaataca aaaaatcatt tattaaagga ggctaaacaa
    88081 tgaacaagga aatgagccaa acaatcaagg tacaaaaaat gatagatgat ctaacacatg
    88141 gaattgatag ccaagccgat aaaatcatca aggaattgca aggacaaaaa gttaaggatg
    88201 caaaaatgct tctcaagact atcaactttg aaatgaatcc aacaaaaaga aagctcgccg
    88261 atgtgttgga agaaaagttg gcttccgcta tcaacgagca agaattacta tttgaaaccg
    88321 atacttttaa cagctgatgt tttatagatg acagtttcat ccgaatctat atcatcgccg
    88381 agagaaaaga atgttgcttt tgacaaaaag ccgataagac ctacaagcgg tcttgatgtt
    88441 gcaagagtag ataccccaat atcaccttgc aaggtattca cgtaaatttg agaagaatag
    88501 aacattccat ctttttcttc gatatttgac gcatcatcgt atccaacgac caaagtatcg
    88561 gcaaatattt tgattttttc tccatcaagc atagtaatta caaattctgg tttcataaat
    88621 tttcacctcc ttaacaatta tttcagcctg tcacactgat aaggaaatta taccaaagaa
    88681 aggaatgaga aatatgaata caccacaaat ttttaatttc gagcaaaacg aagttcgaac
    88741 tattttagta aatgatgaac catattttgt aggaaaagat gtagcagacg ttctaggata
    88801 ttcgaatccg caaaaagcta ttcgagatca tgtggacttg gaggataaga cgcagaacga
    88861 ttcgttcacc gtcaatggaa cagcagttgt tttgattaac gagtcaggcc tttacagttt
    88921 aatcttaaaa tcaaaacttc cctctgccaa aaaatttaaa cgttgggtaa cgagtgaagt
    88981 ccttccaaca attagaaaaa caggtagcta ttcaaacgta cctcaaagtt ttgcacaagc
    89041 attgcgttta gcagcagatt tagaagaaaa gaaccaatta ctcgaacaac aaattgccga
    89101 gtacgaacca aagattagct acttagatac gattctttca tcgacagata cggtagctac
    89161 ttctcaaatt gcagctgatt acggaatgtc ggcaattgct ctaaacaaat tgctaaacga
    89221 gttaggtgtt caacataaag ttagcggaca atggatactt taccgaaaac atatgaacca
    89281 aggatacaca aaatcgcaca caagtgagat tccgaaagcc gatggcggca ctaaagttgt
    89341 aatgaatacc aaatggacac agaaagggcg agtgtttatt tacaacttat taatcgcaga
    89401 gggctattac cctcaaatgg atttagagga aattggttag aaaggagttt tagtatgact
    89461 gacattgcag aaatcactca acgagataga gaaaaaatca aagaatatgt cgaaagttcg
    89521 aagttcttaa cttacaccat gcttgctgaa agatttggaa ttagcaaaag ctacttatct
    89581 ttaattttaa acggtaaaaa gacttctgca gaagcaaata gaatcataga ttcgattatt
    89641 actatgtacg aattgtaaag ggaggaacag ctaatgcaat atctagaagc aaaaatccca
    89701 attccagaag gctatgtaat tatctcccaa gtggattatg aggagttgaa aaaagctgat
    89761 gatactggta gatggatgac gttgccagaa gtactagaac ggattaacag aaaatatgat
    89821 tggtttactt ctagagtttt aaagaaccca agatatagaa atattatcga tatcgaaaaa
    89881 aacaaaaatg gatttgtcta ttatccagtt gaaggaagag acacatatct atttttaaga
    89941 agtaaaacac ttgaattttt agaaacaaat ttttcggaaa tcttaaggag gtaagcggat
    90001 gggaaaattt aatagagcat tagtgttcag cgcaccccta atcatctacg ctttaggact
    90061 ttggggaagc agacaagcat taatcggcac gatcgtttac atggtttgga tttttatggg
    90121 gcttgatgaa gctgagtaca gagcaaaaaa agccagtcgg gagggactga ctagatgaga
    90181 aacaaaaaaa tatctctaac gctattaact atcatcacga ttgttgtatc gcaactattc
    90241 tttttaacta tattaaacga catatcgatg tcggaccgat tgttggttca atcagcttta
    90301 tttctgacct ttgaaaaaat gggtaattac gaaagataga atttgagaaa ttgtttcttg
    90361 ggcaaataac gatgttaccc aaattacaag actaaaaatt cttcctggaa aagttgatag
    90421 attaatgccg aaccaactaa gtatttcgct gggtaagaga aaaaatttct taagagcaat
    90481 caacggattt aaaaaccaga attttcgata atgaatttcg ttgtttttgt caaaaatttg
    90541 agaagcgata attctaaaat tttcttcaag aatatcatct gattgattca aggaaagcgt
    90601 tacaaggcta taaggcagaa ctttgttaat tctgggcatt tccttaacca ttatttctct
    90661 aataggcgtc acattatttt gaaagtaagg atcagattta tagctaccac tatggtcatt
    90721 taatcgtttg aggtcattta tcactttctc aattgtagta agtaaatagt taatcgttgt
    90781 tatttcagac actgcattaa caatttgctt aatataaatt attgtataaa caactagaag
    90841 cacatacaaa atgtagttca ttgaaaacac caccattttt ttacctaaat tataccaaaa
    90901 ggagagaaga aaaaatgcaa gaattagtaa ttttgaaaaa taaagaagct gtgactacga
    90961 gcttacaagt ggcagaaagc tttgagaaaa aacatcaaca tgttttaaga gatattgatg
    91021 cactaaaaaa agatgtgtcc aattttggac agatgtttgt agaaggtaat gaaccagatt
    91081 catacggcag aaatcgacga gtttttttca ttagtagaga tggttttttc ttgttggcta
    91141 tgggttttac aggaaagaaa gctatttact tcaaacaaaa atacattgaa gcattcaacg
    91201 aaatggaaga tgttattcgc aagaatactg ttcctcaaac aattgaagac atgatgatct
    91261 accaactaga agaaatgaaa gatgttaaaa aagatgtttc catgcttaaa aatactatgc
    91321 gaattagcgg acaacaagag tttgaaatta agcaaaaagg aaatatgaaa gttatggaag
    91381 ttctaggagg caaagaaagc cgagcttatg aagaaatcag taaaaaagta ttctcaaaat
    91441 tttggtctga atttaaacgt accttttcaa tcccaagata tggcgagtta cctcgtaaaa
    91501 gattcgatga tgctgtttca tttattgaaa tgtggttacc agaaactgcg atccgcatgg
    91561 aaatcgatca actgaacaga caacaaagac ttttcggtga tgaaaatgaa tagagctgaa
    91621 gcgctaagaa tagggacggt aattgctaat cgctggtgga gacacaataa accaagcatc
    91681 ctaagccaac aacatattga taagcaaaaa gcttggcaac aaataaaaaa gtgactctgc
    91741 cggcaagcaa agagtcacaa agaaaacaca tcataaggag attttagcat atggaaaaag
    91801 aactttccac tctagatcaa tatttgattg atcctgattg gggcaagccg aaaattgagg
    91861 aaacaagtgg tcgaaaaatc agacgaaatc ttttgacgaa tgaagaacta gcttgtgatc
    91921 aagatgattt aggtaacctt gtaactattt gggatcatgt ttatcttatc catctatcga
    91981 agcattcgaa taaacctgaa tatatttacg tcatcgaaga tggcttgatt gatgcgctag
    92041 aagagtatga cagagataac ttgattgata tctcttatta cggactaggt aagaaataca
    92101 ttgctgaaat ggaggcagaa tttgatgagt gaaggaacga aacgcagcga taacaaatta
    92161 ttcaatagtc tgtacaagat aaccgtcaat gatgttgtcg aaaaaagaaa caaactaact
    92221 tatctgtcct gggcatgggc gtgggcagaa gtcagcaaaa tctgcgaaga agtagactac
    92281 gaaatctatc gtgatccaga aacacatcgt ccatacctct ttgatgaaaa aacaggctat
    92341 atggttttta ccagtatcac agtcaatgga gtaaagcgtg acatgtggtt accagtcatg
    92401 gatggtgcaa acaaggcaat gaaagatgag ccatatacct acgaagtcaa tgattatcag
    92461 tggaataacg aaacgaagaa aaaagagatt gttggaaaaa tcgaaaagcg agttgaagca
    92521 gcaactatgt ttgatatcaa caaaacgatc atgcgctgtc ttgtaaaaaa tctagcaatg
    92581 tttgggctag ggctatatat atttgctggc gaagatatgc cagaagatgt ctcgatgctt
    92641 gaaccagcta ctcaaagaag caaaaagcta ttcttggatg ctttacaact ggttgctaac
    92701 aagtacgaaa aatcgattga tgaagcaatt gttgcattga ctgatgcagc ttctataacc
    92761 gctgatgaca gtaaatggac caagagagac ttgggcattc taaaacgtgg cgttaactgg
    92821 cttgaagatc agtacagaga agaaacaaaa gagaagtgat atgagtgttt aaaccattaa
    92881 tcgattcata ttcagcggtt ctgaaaaagt tcaaagggaa agacataggc gcaacgatca
    92941 atgaagaagt gaacattgat cgactaaaga cgatgtatga cggctacgat ggcgatcgag
    93001 tcattgaaat tcgttttatt gatcctagac gtttcaccgt acagcaacga aacttcatct
    93061 atgcgctgat aggcgatatt tttatcgata caggcatgcc aacggacttc tggaaggaat
    93121 tcttctactt ccgttttgaa ggcgtcacag ggcgcaaaat aagcctcaaa gacgaatcga
    93181 atacaactgt gagtgatgct aatgtcttag caaatatcat cttagatttc atctttgaac
    93241 atcatattcc tttcaaagaa ggctatgaga ttttaccagc gaatcaagaa tattacttct
    93301 acaaatgcat tacaaaaaga gtttgttgca tctgtggcaa aacaggagct gacatcgatc
    93361 actttgacaa agcgttagga agacgaaagc gcaaagaagt tgatcattca gagtacacat
    93421 ttgcagcact ctgcagaatc catcatacgg agaagcacaa aataggtgtg attaatttca
    93481 aaaataagta tcaaatcaaa gggattaagt taaaccagga gacaatcaaa aagttaaata
    93541 tcggaggata aggaaaaggt ggtattgaat tgtcagacaa acaaaagaaa cgctattact
    93601 ggcttaaatt aaaagaagat tttttcgaag aagataccat cgaatggttg gaagaacaac
    93661 cgaatggtaa agaatattgt ttattttatc tgaaactctg tcttaaatct ctaaagacag
    93721 aaggaatact agttagaaat gtaggtaatc tgatgatacc ttacgatccc gaatctctag
    93781 caaaactaac aaattcaaat acggacacag tgaaagtcgc tatggatcta ttcaacaaaa
    93841 tcggactaat aaaaatactg gacagcggag agatatatct aaatcagcta agtgaattag
    93901 taggatcaga gactgaatac gctaggcaaa aacgaatcca aagagcaaag gaggacaatg
    93961 tccagaagtt gtctggaaaa ggtcgcctag agatagagtt agagaaagat atagatatag
    94021 atatagataa agaagaaaag aaaggtaagc attctgacga acacttacgc cttgctaaaa
    94081 aattgcaaag taatttaact gaagattttc caaaagaaat gaacaaagta gatatcgaaa
    94141 aatgggcaga cacaatcagg ttgatggaag aaagagataa agcgtctata gaagcgattg
    94201 agtatgtgat caattggcta cctacaaatg aattttggtt tggaaatatt agaagtgcta
    94261 agaaattgag agaaaaattt gagaagctca aattcgaaat caaagcagac aagaagaatc
    94321 ataaaaagca aagtcaaaaa ctacagtaca gcaatcctag tgaatatgac gacttgccaa
    94381 tttaaaaagg agatgcatca catggaaagc ctagcaaatg ctatggagaa actaataaga
    94441 agagtattag tgcaaagcgg aaaatgtcca gaatgtagcg aacctttgta tagttggcga
    94501 gctaaaaata aggatggttc agaacgttgt aaaccaacat gcatgagttg tggttataaa
    94561 gcgttacgtg tgaaagagga tttacagacc gaacggatat ataacgacag cttaaaagca
    94621 cgagcattga gtttttttca aaatggttcg gtattaacag ataaaacttt gtttaaatgc
    94681 aaaatggaga attatcacgt agtggaccaa gaaacgaaaa ttgctttaga aagagctaaa
    94741 agctatgtaa atgatgtcct actgaaccat cctgcacatt tcattctatc agggaaatca
    94801 ggaagcggaa aaagccactt gtcaatggcg acagcttggg aaatacttga gcgctcaaat
    94861 tatgacaaga aaatactttt tataagctat caagagttat tagagcaaat aaagttttct
    94921 tataacaatg ctgaactgag aaaagaaatt gaaggatcgc ttatagccga tatcaaaaca
    94981 actgatttgg tggtttttga cgatattgga gctgaattag gtagcggggt atcaaatagt
    95041 aggcagttta caaacaacac gttaaacacg ctcttagaag ccagacagaa caaggcaaca
    95101 atcatcacaa caaacttatc tggtcccgaa ctaagagaag cctacggtga aagaattgtt
    95161 tctaggatat ttaagaattc agaaggttac gcgctgaaat tccaacaaac agcagacaag
    95221 cgcataaaac cagtgaaagg tagtatcgca tgaataaata ccgtaataaa aaaactgttc
    95281 atcgaggtat caagtttgat tctatcgcgg aagcagagta ttacgatcta gccttgtggc
    95341 aagctgaagc gaacggctgg aaagtaaaac ttcaggaaag atttgagctg atgccgaaat
    95401 ttgaactaga cggaaagaag tatcgcaaga tcgagtatat tcccgacttc acattttata
    95461 aaaacggcaa acttgtcaaa gtcgtagatg tcaaaggaat gcagacaaaa gactttaaga
    95521 tcaaggcaaa gttgttctgt catcaatatc aagtgccgtt gatattagct aaaaaatatc
    95581 ggaatacgtt caaggaagag cgtttttaac gaggtggtcc atcatgacaa cagaagaagt
    95641 gattcaaatg cgtattcgaa gcattcaacg tgaaattgac gatctggaac gaacaaaggc
    95701 agtgatggtc aatgaaacgg cgagaaaggc aatcgatttg cacatagaga atttaagaag
    95761 ggaaattcgt agattggagg aatgatcgtg gataagaaat cagcaatgaa acgaatcatc
    95821 aaactgacac attctgagaa ttggcaagaa gacaaagaaa tagttgcaga agtccaaaag
    95881 ctcggtaaat caatgtggaa tgaaaagccc aaacggagaa cgccaagaaa aattgcaatc
    95941 tggcatggtg accgaattct agtgacaggt accgctgaac agttatctga aattactggt
    96001 ctgagcaaaa acattatttg ggatagagct aggagtttat ggattgattc aaaaggacga
    96061 cagtttaggt atatggagga gaaataatgg acgaactaat cacaaaagta gagcagtggg
    96121 ctaaagacaa gggactggat caagcagatc caaaagcaca gtttttgaaa gtagctgagg
    96181 aattcgggga aatagcttcg gcgatggcaa gaagtaatga tgaactattt aaagatagcg
    96241 taggagacgt tatcgtcacg ctgattatcc tttccatgca aaaagggaca aacgtacaag
    96301 agtgtttaga aatggcatac aacgaaatca aaggacgcac agggaaaatg gtagatggtg
    96361 tattcgtgaa gtcgagtgat ttggaggatg tgaaatgaaa tacgaaatac cactaagtga
    96421 agcgggcatt caagcaatta tcaatggtcg ggaggttaac ctagaacttc ctgatggtac
    96481 tgaattagtc atcagacaaa gttatttgaa agatatggca gctccagtat taattgatcg
    96541 ttttaacgtg actgattctg tggtagagaa ccacttaaaa gaatttcgat caagtataga
    96601 caacactttc agattaggga gttgattgac aatgaacacc agacaccgca gagtagcaaa
    96661 actaagaaaa caggaactaa atgtactaaa gacaaagttt gaaaaagaat atggaatttc
    96721 agcagaagaa acatataaag tggcaagtca gtgtgttgct gatgcaagtg atgctattcg
    96781 taagtttgga atttcgatat taagtgatga tcgtaaatgg gaggaaaaag aatgaaacta
    96841 aaagacggat tttacgctag cagtcacggt atcggcggtt taatgctaga tatgccgaca
    96901 aagaatccta aaacacgtaa gaaaccaaaa gtcaaagtcg gtgacatggt ccgctgtgaa
    96961 gcagaggagt tcatttatcc atttcgtgga tatgtagaac acgtctataa tcactcagcg
    97021 atcattcgca ttgaaaacac gatggaatgt gataaatgga cagctaaaag caaagagaat
    97081 ttagcagtag tgagattggt ggatatggaa ctaatcaatg acaaataaaa aagccggatc
    97141 gctccgacta acataataaa acagacaagt ttattatatc acataaaagg agcagtttga
    97201 cttgatgcaa ttgttacgag aggtagattt caaacagaca agatgtaatg cgagagatgt
    97261 gctgaagaac tttcggcgtt tggagcggat ggcaggtcgc tctttgatag atattaagtc
    97321 gccgattatt acggatatgc cgaaggcacc gaagcacggc aataaggcag aggatgcatt
    97381 gattcagatg atggatatag aagcggagag agacgcgatt ttagcggctt tgatggctct
    97441 tagtctgatt agtcgtcaga tactctacta tagcttctgt gacgtaaata agcactctaa
    97501 ttatgaaata ggtcaattga tacgaggata cggagagaag aatgtagaga agctgaaatc
    97561 tatcgcgctg atcgaatttg ctgaagcata caaaaaaggc gtgttagttc agtatcgttg
    97621 attttgtagg gtttttgtag ggatagtgta gggtttttga gtgttttaac gtgatattat
    97681 gatagtgtcg aaagattagg aaacaggatc gacaaaataa aatgtaaggg agggaatctc
    97741 cctcatcgtt ttaaattaag cttcgatagg cagcaacgga aatattaaga ataaggatgt
    97801 gaatttcaac tcctcctgat tgttcttatt atctatcatc cgttgctgtc tattaattta
    97861 tgtattggag ggtaagaata tgaaattatc gattgaaggt acttcaggag aaataaaaga
    97921 gttgctccaa gctattggtg gtagcaagga gcaaaatata aaaattgatg atatttataa
    97981 agaaagtaga gattttttaa ttaacggtca agcttttgct cctagttttt aaaatcttca
    98041 gaaacagcgg aaagaaattg attataaagc tttatatatt caaaatatgc atcaaatttt
    98101 gcatctttcc cttcaattat ttgagattta acaatatctc tgacaaaagg taatgttgca
    98161 attgctaaat catgagcgcg ttgttcattg gttaacatag ttttcacctt cgtatattta
    98221 tttcagcgga ccactcgctg ataaataaaa ttatacactt agtatttatt ttcacaatat
    98281 taatttgtca ctgtggcgga gggtagacgc ttaaaataag ttcaatacgt cgagggatag
    98341 ccttaacgtt ttatgatttg accatgcaat gttcgattca ttgccagcga ttttagcaac
    98401 tgagggttgg aaatgggcgc tcaaagtaca cgagcaaggc gaggtcgata gtaatcgatg
    98461 gaatcggtgt aggttgcttg atagagctat aactgcatct cattgttgag atgtagtttt
    98521 tacatattag atcactcgtt gagtggtctt tttattttgc aaaaaggagg taacaacaat
    98581 gtatagacca caatatttag aacagaagta tgaagtaatc actgtgcaaa acggtaacgg
    98641 tgagatagta cgaaagtata gaagaccaat aaagagcgat acatacaaac gaaaggaaag
    98701 caatgaagtt attccattgt atggcaaaag aatagctaag cattaaataa gattgcgaaa
    98761 ggagacggaa catgaccgag gaattctata gatggctatt acagttgaca agagaagatc
    98821 gtttggttaa gttctatcag tctcctaaat ggcgcaggct tagagagaaa gcgatgaaac
    98881 gagatcacta tgaatgccaa gagtgtagaa gactaggtaa gtatcataga gtagagaacg
    98941 ttcatcatat aaaggaagtc aaggatagac ctgacttagc tttagattta gataatctta
    99001 tttgtttatg tgttgaacat cataatgaag ttcatggcag atatcttaca gcattagata
    99061 aacaagagaa gaagatagaa agctttgcta acttcgatgc aagtgaaagg tggtaagtgc
    99121 atgatcatca atgataatgg cagagagtat gatacagaaa agattgaaga gtattcatct
    99181 tatactcagg gattgattaa acgtttgata tacgttcgct atgtaggtat tagggatctg
    99241 ttatcagata actgttgtag taaatacaaa gtgaatcaag taagagaagc gttgaataaa
    99301 gataataacg tcgaaagaat aaaaaatgtt tttggatata gtattgaaga gattaattat
    99361 tacattgact tcgctgaagc tttcattccg atggtgagat aaccccccct taaaataaat
    99421 cgcaaatttt ttgggggtga tgaaacggag ggggctgtca ggaaaagaga ttttttcgaa
    99481 ctttatcatg aaaggagggc taaaatgttt aaaaacgaat tgtctcaaaa tcgctacaga
    99541 gaaaaattac gccgctcttt aataagccaa ttggaaagtc agaaaacaaa tattgagcca
    99601 ttcttagata atgttgatcg ttatatcagt ttatgggaaa cggcgatatc actggaagaa
    99661 gatatatccg agaacggcat tagactggag aatggtaaaa agaatgaatc agtagcgttg
    99721 cttgtttctg tcaacaaaca aatgggattg atgttggata aacttgccat tactcctgaa
    99781 ttggtaggtg aagcaaatga atcaattcct gagttataag catattgaaa attggttcaa
    99841 agctatagaa gaaggcacta tcaaggtatg caaagagcaa ttattgctaa aaaattatct
    99901 agaagaaaga gtctttacta gagaagatat ttacttcgat aagcagatgg tagaggattc
    99961 aatcaatata ccagcacaat actttccatt cgaattaatt ccgtgggaaa aatttctaca
   100021 atgttttatt tatggtgttc gatggaaaaa agataaaaca ctagtgttca atagatatct
   100081 ttcattaatg ggacgtggta atggtaaaac tggttttgct tcttggaaca acttctttct
   100141 actaaccgct aaacacggta ttaaaaatta tgatattgat atctatgcca ataatgaaag
   100201 ccaagcaaag actagttttg atgatgtatt taaagtaatt aaagatcatc ctgatttaga
   100261 taaaaaagta tttaaagcta cgaaggaagt tattcaaaat atcgctacaa acagcaaact
   100321 tcgttataac acggcaaatg ctagaacaaa agatgggaag cgaccaggtg caaaccgctt
   100381 tgatgaaatt cacgaaaatg aagattattc aatgataaat gtggctactt ctggtggtgg
   100441 taaaattcga gattatagag aattttatga tacaactaat ggtcatgttc gtggtggtcc
   100501 gcttgatgac attatagaag aatcaaaaat gattctttct ggagaacttg gaattgacaa
   100561 ggatggagca gaattttcta gtttgtttcc atttatttgt cgcttggata acgataatga
   100621 agttgatgat cccgacatgt gggaaaaagc ttgtccaact attaattaca atgcagattt
   100681 aaaacggaaa atgtttcaag aatactctca aatgcaacgt aatgctggtt taagacttac
   100741 gttcatgacc aaacgaatga acagacctat ggaagataca cgatttgctg ttgcttcata
   100801 tgatgatgtt ctgcatacga aagaaaaaga atttcctgaa aaaatggatg aagtgatagg
   100861 aacagtcgat tttgctgata gacgagattt tgccagcgtt gggttgctag gaaaatacga
   100921 taaagatgtt tattttacac aacatacttt tatccacgaa tcagcccttc gattacaaaa
   100981 catcaaacga gaggttatag atatttctat agatcaagga aaatcacaga tcgttcatgg
   101041 aaaaaatata gaagctgatt atattgtagg ttggtttctt gaaatgagta ataaatatta
   101101 tattaaaaaa atcgctatgg atatgtaccg tgcaaaaata ttgaagcccg ctttagaaga
   101161 agcaggtttt actgtggaaa ttgttcgaag cggatctgtt acacatggta tgttaaaaga
   101221 tctggttgat gaccttttta ttaatcaacg tttatttttt ggtgacgatg cgattatgcg
   101281 ttggtattgc atgaatgtat atgaagagca tatttctaat ggaaatatac gctatgaaaa
   101341 aatagaacct gaaactagaa aaacggatgg ctttttttca ttccttcatg gtttgaattt
   101401 tttagatgat atttatgatt ctgctcctgt aacagtcaca aatagctcag tagaaaatac
   101461 aggaactgga tttactcctc tagtattcta acttgaaagg aggtgagaaa gtggggattt
   101521 ttcaaaaggc ggtaggatac ttcacaaaaa aagcaacggt tcctttagaa gaatactttt
   101581 gtaaattgca agttgatttt gtgtatcgaa aatttgcgat tgaaacttgt attgatttga
   101641 ttgcaaatgc gatgagtaaa gcggaattca agtcatatga agatggaaaa aataaaaaga
   101701 atgatcttta ctataggctg aatgtagctc ctaataagaa aaataatgca acagaattta
   101761 gaaaaaaact gatcaggaga ttaatattct acaatgaagt attgatcgtt tctccgtcta
   101821 ataattctag cgaaatattt attgcggata gttgggatgt cacagaatat gcattgaaag
   101881 atgatgtgtt ttctcaagtg caaattaaca acatagtcct tgatagagaa tttctagaaa
   101941 gtgatgttat ctatataaaa tacgcagatc aacaaattag gcaactagtc gatgcgtatt
   102001 atcaagcgta tgggaaactc atttctagtg ccatgaatgt ttacaagcgc tctaacgctc
   102061 gtagatacgt actgaaaggg aatttattcc gaccgcaaga caatacaaca caagatcaaa
   102121 tcaataaaat gatgacatca caatttaagg cttttatgga agctgataat gcaggtgcgg
   102181 tatttcaatt acaaaatgag tacacattag aagatttcag cggaaacttc caaagcaatt
   102241 caagagatat aaaaaactta atagacgaca tctttgagat gacagcagca gcgtttcacg
   102301 ttccgaaaaa cctactaaag ggagacatga gtgggttatc ggatcaagtg gacgcttttt
   102361 taatgttcga aatcataccg attgctgaac ttattcagga tgcgtttaac gctagtctct
   102421 atgaagtaga agaatacttg tcagggaatt ttgtacgtgt ggatacaact atgatcaaga
   102481 ttactagctt caaagatttg gttgacgcta ttgatgtagg cattagaaat ggagtattta
   102541 caatcaacga aggaagagaa cgcgttggaa atgatcgctc tgataaggcg atggcagatg
   102601 aaatatttat aactaaaaac aatcaacaag tatcgaaagg aggtgaggcg aatgacgaca
   102661 atgaaaacat ttctagcagt aaagaatgaa ggcgcagtac cgcaaatttt tattcaggga
   102721 tttattggtt ctagttggtt ctttgaaggg aatactgaca agggaatcaa aaatattttg
   102781 gatagtctag gtgatcaaga agaaattgaa gtagtaatta attcaaacgg tggagacgta
   102841 tttcaaggga ttgctattgg gaacttactt aagtcaaata aagcaaaagt taacgttgtg
   102901 attaacggct tagccgctag tgctgcttca attatcgcaa tggctggcga tactataaaa
   102961 atctacaaca atgcacaatt gatgattcac cgcgcttcca catacggaga aggaaatgtc
   103021 gatgacttcc gtacgattgc tgaccaactg gaatcaattg ataaatcggt aaaggcttca
   103081 tataaaacac gattcaatgg cacagatgaa gcattgcaag aacttcttga aaaagaatcg
   103141 tttatggatg cagaaacagc tttgagttat ggattggtcg atgaaattat cgatgcagaa
   103201 aatagctcag gtactgaagc taaaaaagaa caaagcgttg aagaaatttt gaatgacgtt
   103261 aaagaaaaaa gagcagaaaa aattgctgca tttacagcag cattaaataa aacatttgga
   103321 caaggagatg taaaataatg acagttaaaa atttaaaagg tgtaacagct gcaagcgacc
   103381 aattgatgaa agcttttaaa gatggtaacg aagaatcttt tagcgcagct atggtaagct
   103441 tatctaagga aattcaggat aaaattttag aagaagcaac agcaaaaaat caagatcaat
   103501 tagtattaat gaaccgtggt cagcgtgtat taactacaca agaaacaaaa ttctataacg
   103561 aagtagtgaa aaacgaaggt tttgcagggg tcgaagaatt agtgccagct actgtatttg
   103621 aacgtgtatt tgaagattta gaacaatctc atccactatt gcaaaaaatt acttttgtta
   103681 acacaactgg tgtaacagaa tggattgtgt cacgtggagt caatccagca tggtggggta
   103741 aactttgcga agctgttaaa aaagttttag ataatggctt tgatgtaatt aacatgaagc
   103801 agttcaagct atcaggttat attcctgtat gtaaggcaat gcttgattta ggtccagtat
   103861 ggttagatcg ttatgtccgt actgttttag tagaatcatt gagaattgca ttagaacaag
   103921 caattgttga tggtactggt aaagatatgc cagtcggaat gatgcgtgac atgagcaaac
   103981 aaactagcgg agaatatgct gaaaaaaaag cagaacctat tacagcttta gatgctgtaa
   104041 ctatgggcgg tttgatggcg cgactatcaa aattcaatat cgaaggtgtg aatgatccga
   104101 tttatcgtaa tgtgaatcct tctgatgtgg tcctaattgt gaatccaact gattactggt
   104161 ctaaagtatt cccagctaag actgtactaa ctgctaatgg agaatacgta caagtattgc
   104221 cagtaccagt ttcagatttg cagtcaacgg ctgtgccaga aggaaaagca gttattgggg
   104281 tagcctcaga ttacttcatg ggtgtaggat ctacactaaa aattgaagct tcagatgaat
   104341 accattttgt tgaagacgaa cgcatttatc tagctaaaca atatgcaaac ggtcaaccta
   104401 aacgtaacga tagtttcatt gtattagata ttagcgcttt gggaactact actacaacta
   104461 caaaaccaac aaccacaaca actacaacac aagcgtaggt gatcagaatg aagtatattc
   104521 tttgtcagcc ggcaatcaat cggtttaaat gggagcttga agtttgttta actaatctga
   104581 agaaactagg aatcaaagat atcgtattgc ttttcagcag acacgatgat cagattccta
   104641 ttttttttga gaaggaatat ggtgttgaag ttcatgtgta cgatgatctg cgggacgaca
   104701 aagagtatat tccttcgatt aaaccatatt tatggtggaa atatttagaa gaagatcatt
   104761 cgcgtgagga cgaccgatat ttctatatcg attcgaatgt cattttcaat aaaagaatta
   104821 atttgcgcaa attgccttct aaagatgatg tttggtattg tagcgactgc tgtagttatc
   104881 taagtcttga ttatattaga agctgtgaaa acggagaaaa tattctaaaa gatatggcaa
   104941 acattgtaaa tgttacagta gaatctttgg aaactataaa cactaattca ggaggcgcac
   105001 agtgggttat taaccgtcct aaagcgaatt attggaaaaa ggtttatctg gattctaatc
   105061 ggctatatcg ctaccttaga gggcaaaaaa caaatataca aatctggaca gccgagatgt
   105121 gggcacagct ttggaacatg atgtatttca atattggtcc taaagttcac gaggaattag
   105181 acttttgttt tgctactgat ccaatagaaa aagttaaaga agtaaaaatc ttacacaatg
   105241 ctggagtaac aacaaacgat gaagatttat ttttcaaagg gagatacgtg acttctacgc
   105301 cttttgatga agatttatca tttgtaaaca agaaaaaatg ctcttacgca tatgttaaag
   105361 caattaaggc ggtggttaga tgacgcctga acaagtgact gaagaattgc taatagctgt
   105421 gaaggataat atttacgtta cctggaacga agaagatgag tcaattaaaa agatgatagc
   105481 taaaaatgct gtttatcttc aaagtaaagt gagtacaaca ctttcttttt ctcctgaaag
   105541 cttagaatac ggattgctaa tcgaaagatg tagatacgac tggaatcgtg ctttagatga
   105601 gtttgaacaa aatttcgcta gtgagttatt aggtttcatt caacattatg cgctacaaga
   105661 atatattgca ggtgatgtga atggcgaata atcgtagact cgaagaaaca ttcaacgatg
   105721 gttggttaaa gattttgacg caaactacca aaagaaatga actaggaaaa aagattggtg
   105781 tagaagatac agaaatcact tctttaaaat ttagaaatct ttccatgaga gatagtgata
   105841 taacagctat ggatgcgatg ggatcgaaat taactaagaa agtaaagact ccatttcatc
   105901 caatcgccaa gaaatttaat aaagatcaat attttatcgt aatcgatagt atgcgttaca
   105961 acgttatcta tgccgattac gataattttt atatctattt ttatcttgaa agtgtgggtg
   106021 aatatggtga ttgataattc taaagaaaaa gaacgtttaa ataagcaaat ttctgctatc
   106081 aaaacttcct tagaagagca ttttggcctc aaactctttc aagactccgt aggcgaggat
   106141 gagctacctg atgattttaa ttacttcatt ctcgaaacag gagaaataga aatgatcact
   106201 gagccaaaat atagcgtggg tcaaaatcta tatctaactt tctattcaga aaatagagaa
   106261 gatttaacag gagactcact agatattatt tcattgattc aaaatcgttc gattcgtttt
   106321 cagagaatgg atcccaatca tttaaaacta gagaaccaag atcgctatat cgatcaattg
   106381 gtatttacgt ttagacgatt attgaagagt gattgtcatg gctaaaaata gttgggagct
   106441 aaaaataaat ggacatgatg aacttcttgt gcggatggaa cgctattcaa gcgagagcga
   106501 acgactgatt aacgaagcat tgaaatcaaa aggttcggct attgcagtgg ataggattac
   106561 agaaaaaatt cctgtttctg aagcagattt aagaagaggg caccaacacg caaaaaatag
   106621 tcgtccactt aagactcaat acattaattt gggtttcatc attagaccta caagaaaatt
   106681 tgagtattta aaatatcctg atttggggat aggtacttct aaaagaaatc agccggacga
   106741 atttatgaga agaggattag gtcttgcact tgatccaatt acagaacttc tgattcgtca
   106801 attcgataaa ttaaataaat agggggaaca acaatggcta aaacaaaaac tgtagtaaca
   106861 acgttcgata acgtaagtat caaacgaatt gcttttaatt ttaagaacgc aggaaatgca
   106921 atcgcaacga attgtaatgg acaattagat ggcgaaacag aaatgcaaac ggtggttaaa
   106981 aaatgtggag cgacagaagt aaaatcaaaa tctaaaccaa tcaatatgac ggtaacaatt
   107041 actgcacatg taccgatgga agtttatcga cgtttcaatg ggttgaaaca agatggacgt
   107101 attaaaccag gcatttactc ttacggtcct gattccgtag gcgaagattt ctcacttgct
   107161 gcagagatcg tggatgactt cgaagaaaat agaaagttag ttggtatgtt agcatgcact
   107221 tcgaatacag gattaacatt ctctattgaa aatggtgcgg atgaagtagc tgcgttagaa
   107281 ctagaaacaa aagttatgca agatgaattt ggtaaatttt atcatgaagc aattgttgca
   107341 gaacttgaag aagacttaac agatcaatgg atgacgaatc tatctgctga tgtgattaaa
   107401 aaaacttcag ttgtgacaac tacggccact caatcacagt aaaaaaaacg gaggtagcga
   107461 aatgaacgaa gattactcaa aaattgaact aaacgatgga acaattttga atttagaacc
   107521 taaactgaat atcaagaaat tattgatgat caatagagat tttaacacag acgagtttgc
   107581 aaaaatgtcg atgggaaaag gctctatgga tattacagtt attcaaggtg caaaagccgt
   107641 atatgtagct tatcgtcaag cgaacatggt cgattacatt tcattcgatg aatttataga
   107701 taaatgggat tttgatatgg aggttgcagt agctgtatac agtactatga tgttcaaaca
   107761 agcacgtgat gcctatcaaa aagaattcga aaaagcaaat aaggaaaaaa agcttcaaaa
   107821 gtaaaaatgc caaagctctt agttgaaacg tgggtcgatg tctattcgat gttgaccgac
   107881 gttttttcta tgccttcaga tttggtttta agcgatatct gtttagatga cattttgcaa
   107941 atggcttaca acaagagcgc ttatgaagga tggaagaact atgcaataaa tcaatcccag
   108001 aaaaactaaa ggaaaggagg taaaaaatgg ctaaaaagag aacggaagca gaagtaactt
   108061 tcatagctaa cgatgacgga ttgaaatcta cgttaaaaga aatcagtgct gaattaacta
   108121 aaaatagagc agaattaaaa ctagaacaag ctcaattaca acagactggt tctgaatcag
   108181 acaagttagg aagtaaatta tcttctttag aaaagcagta tgaattacaa agtcaaaaag
   108241 ttgaagtaac tagtcaacgt ttagccaatg ccaaaaaata ttatggagaa aattccaccg
   108301 aagttcagaa acttgaaaga gaactgatta atcaacaaac agctcagcaa aggttatcta
   108361 atgatataga taaaacgagt aaggcattgg ctcaatctaa aggtgaattt aaaacgtatg
   108421 agtcaactat gaaagactta gataatgagc aacaacatct aaagtcaagc gcatcattag
   108481 tagaatccga atataaaaaa tggcaagcaa ctgctggcca gtctgctaca gaatctgaaa
   108541 aattagcaaa agcacaagaa tatgtcggca aacagagtga tattgctgaa caaaaaatcg
   108601 aagtgctaaa aaaacaatta gatgccacac aaaaagaatt tggagaaaca tctaccgaag
   108661 ctttagaaat gaaaactaag cttaatgatg cggaaagaga attcgaagaa ttaagtaatg
   108721 ctgctaaaaa cgttgatacc tccacagtag atgatatcgg caaaaaactt gatatgggta
   108781 atttaatgga agctactgat cacttgtcag tgatcggaga taagcttatt gatgtaggta
   108841 gtaagtctat tgaagcagct ggaaaagcac aagctatgca ggcccaattt aaacaagtct
   108901 ttggctcttt agaaggggaa gcacaggacg ccgttgaggg aatggctgaa gaatttggaa
   108961 tgttaccaaa tacgatcaag cctgttttta cacaatatac gtcaatgttt aaaggacttg
   109021 gatatgatac caaagaagct atggagttag ctggtgatag tactcagtta gcagcagatg
   109081 cagcagcttt ttacgataag tctatggatg atgctagtga atctcttaat tcatttataa
   109141 aagggaacta cgaaggtggg gagcaaatag gtttatttgc taatgatact caaatggcag
   109201 cttatgctgt taagcataat ttgataccag cgactgaagg agcaaaaaaa gccagtgaag
   109261 agtcattgtt agctgttgaa aaagcacaat ctaagtatgc tgatgctatt aagaaacatg
   109321 gtgaaggatc tttagaagca agagaggctg ctttaaaact taaagatgcg caagataaaa
   109381 taaatgaaga attaggccca caaacgcaaa aatggtctga tttagatgag gctaccaagc
   109441 aagcagttcg agttcaatat gctgaagata tgcaaaaatt agccggtgct acaggtcagg
   109501 ctagtaggga gtctgatggt ttagaaaacc aaatgacaag agcaaagcaa gcgttagaag
   109561 atttttatgc ctcattgggt gaagatatac tgcctgtgtt tatcaaaggg ttgcaagcag
   109621 gagcgaaagc tttgcaagga ttagccgaat ggtggagtaa acttgatggg ccaatgaaaa
   109681 atttcatttt agctcttgga ggaattctag cattattaag cacattagct cctgttataa
   109741 ccgcagttgt tacgatagtt ggcacatttg gttctacagt tttgctgcca ataataggaa
   109801 ttatagcggg cgttgcagct gtaatagcga ttgtaattac agcgtttcaa aactggggcg
   109861 caatcactga ctggtttagt gatttatgga aaaaatttac cgattggtta ggtgatacct
   109921 gggaaagtat aaaagaaagt gcctcatcag tttgggatgg agtcaaagaa acctggtctg
   109981 gatttgtaga ttgggttcaa gaaatttggc aaggagtttc tgattggttt ggagagttat
   110041 ggagcggatt agttgaagga gcttccaaca tctggcaagg agtccaagag acttggcaag
   110101 cattcgttga ttgggtttca aatatttgga acggagtcaa agaagtatgg tcgattattt
   110161 gggcagacat tgtaggaatt gttcaaatac catggacatt aataacgtca ttgattcaag
   110221 ctggtattaa tattatcgtg ggtatctttg atgtagctgg acagttatta ggcgcagctt
   110281 ggcaagctgt ttggacacct atttctgatt tccttaaaaa tacttgggat actatgacac
   110341 aatggataag catcgcttgg aatggaattg taactacatt ccatactata tttgatccag
   110401 tagtggcatg gtggaatggt atatggacat ctattagtac tacggcttca aatatttgga
   110461 attcaattag tgcaacagct tctagtattt ggaacagtat caagaataca atcactagct
   110521 tggtacaagc agctgctaca gtaattcaaa atatttggtc aactgtatct agttggttag
   110581 gtggaatttg gaattcaatc agctctacag catcaaatat ctggaatagt gtgactagta
   110641 gtataagcaa tgctataaac gcagctaaaa gtgccattca aagtgtttgg aatagtatat
   110701 cttcgtggat cagcggaatt tggaacggta tcaaaaatac tgctttgaat ctttggaatg
   110761 gaattacaag cactattagc tctaaagtaa acgatggaaa aaatgcaatt tcaagcggtt
   110821 ggtccaatct aacaggtatt gtttccgaca tattcaataa tgttaaaagt acaattgcta
   110881 acatatggga aggcatcaaa aagactgtta gcgctccaat tgattggatt agagacaaaa
   110941 tcagtggcat ttttgataat ttgaatattt ctataccaca tattccgtta ccggaattta
   111001 tcatggaagg cagctttaac ccgctaaaag gtcaaatccc ccatttgcgt gtaaaatggc
   111061 atgctaaagg aggtatcttt actaaaccaa ctttactagg tggaatgaac ggtgtcggtg
   111121 aagcaggacc tgaagcagtt ttacctttga aaagatctgt tttgcaagaa attggtgatc
   111181 gtatcttgag tagcacatca gtttcatcta gggcacaaac gattcaacct gtgaataact
   111241 acgaattcaa tttcacaatt gatggtaacg cagatgaggt tactatgaag caaacaactc
   111301 aacaaatcat tgatagcatt acaaaaattc aaaatgataa tgcttcggca tggcgttaaa
   111361 caggagagta tttctcctgt ttttttagta ttaaaaagga tgtgaaaaaa tgactgattg
   111421 tatacattct ataatcgatg gatttcctga ttatttgcat aaattggctt tagctgaaag
   111481 accaaccata ccttctccaa aaagacagag agttgaaact tctgttttag gtaggttagg
   111541 tggcttagta caagattact cgtttgaaga tatgtcgttt acattgcact ataactattt
   111601 agaggatgtg gaagaccatc aagcgttcaa gcaatcgttt tatatcatgc gtcattggtt
   111661 aaactatgca aagaaattag aattctctga cgatcccaac gtctattacg ttatccagac
   111721 tatcgatatt ggggatgcag aaaacgatat tgttgaatgg ggagagttcg atgtaaatat
   111781 tactgcgaaa ccattcgcaa gagttcaaga agatgtacct ataaccgtag ataaaccaca
   111841 gtcatttaac ttgctgaata atagtttaga agaaagtttt ccaaagatta tcatcactcc
   111901 ttcagctact tcatgccagt tcatcttaaa tgattatgtg tttagtttcg aaggcttagt
   111961 agcaggaact gatgtagtca ttgatagtga tttgatgctt tgctacgaag agcaatcgga
   112021 cggagatatt ttagatcggt ccaacaaaat gaagaccatg caatatccaa cgttgcaagt
   112081 ggatattaat cattttaatt gtactggttt gagcaaaata caaatttatc gtaatgggtt
   112141 aaggtaggtg aaatagatga tcgataattt aataactatt tacgataaaa atgacgcgaa
   112201 taatttagct gaacatttat atgatacgca aggtttaggc gctttgtcag actggttaac
   112261 agctactgtt agcaataaac taaacggagc cgagatattt cagggtactt attcaataaa
   112321 cggaactaat gcagatttga ttgtagaagg acgtattatt cagtgttatg tagatgaaaa
   112381 tcgagcaaaa cagcgtctac ggatttatta tgcaaaaact tctgtaatag gcaatacgat
   112441 agaagtaaaa gctgaaccta ttttcaatga tataagaaaa tcggtgttga ataaatatga
   112501 cagcggaaca gaaaagatca ctgctactca ggcatggcaa aacgcaaaag ttttagcgaa
   112561 accagctatc ccttcgcagt tttctttctc gtcattagta gatacgcttg ctaatgtgaa
   112621 gatagaaaag gcgaattttt tagaattctt tggtggaaaa gagggatcta ttctagatcg
   112681 atttcatggt gagtttctaa aagataataa cacattacgt catgaaaaaa gtctaggtac
   112741 ggatcataaa atcaaagcga tttatactaa aaacttaact ggtcttgact tagagattga
   112801 tgctcaaagt gttttagttg gagtttatcc attcattagc agctcttcag aaggagaaga
   112861 cgagatcact ctaccagaag aagttatttt cacggattac gtggatgatt atcctgctgg
   112921 atatgtttct tttgttgatt ttaaagacaa agcgactgat gtagccacat taagggaagc
   112981 tgctaaagac tggttgaaaa caaacataga taaacaaaaa ccacaagtga gtggttcgat
   113041 tgaattagta ccattgaggc atcaaagagg ctatgaaaaa tttgttgatc tagaaaaagt
   113101 ttcgatgggt gacggagtag atgtgtatca tccacagtta aaagtgaata tgtcagcgag
   113161 aattgtggaa tatacgttta atgttctaac caattcatac gataaattag ttgtaggaaa
   113221 cgtcaaaaca aacttcttag aaaacacaga gaataatgtc agcaatttga ttaatgatgc
   113281 cattgatcaa ttgaaaaacg gtggcgaaat cagtgattta ctcaatgata ttgtagatca
   113341 tcaaactgat atgattactg gtcaaaatgg tggttatgtt ttattagatc ctaaagaagc
   113401 gcctagtcgt attttgatta tggacacacc agataagaat accgcaagga atgttttaca
   113461 aatcaacaat gctggtattg gtttttctaa aactggcatt aatggaacat atgaaacggc
   113521 atggacgtta gatggcggat tcaatgcctc gtttattacg gctggtgaaa tagtaggaat
   113581 tactattaga ggtactacat taattagtga tggtgctgat tatagaacaa gtattgctaa
   113641 tggcaaaatg acttggtact caaaaaaagt taacaaagat attatggagc tagaagcacg
   113701 tgattatgta agtgctgatg ccggtattgt atcatacacc atgaaaactg gtggtggttt
   113761 catgattaga aatccacagg gtaacttggt ttttagtacg tgggataatg gtaataacag
   113821 accgtttcta tcttttggtg cgcccaattt caggtatagc aatgctagtt atgtaacttc
   113881 tggcgacggt agttctttaa gcattaatgg tagtgcgggt aactcatggg aatttaaggt
   113941 agctggtagg actatgaaat ttactagtga tggtatgcta acgttaccag gttgtttttt
   114001 tggttcatgg gaagatggga aacttgctag gtttgaacaa tcaacggtac aagtatataa
   114061 agattttact gttagaggta ctaaaaactc aactgtacca acagaacatt atggacaacg
   114121 actattgaac gcttatgaaa ctccagaata ttatttcgct gattatgggg aagccgttac
   114181 aggtgacaat ggtaaagttc gtgttgatat tgaccccatg tttgctgaga cagtaaatct
   114241 aagtcgatat atgacacatg tgacacctac agaactagtt ttgtgtgctg ttactcatga
   114301 agatattgac catttcatca ttgaaactag taagccaaac gtattagtta gatggaattt
   114361 agtggcacac cgtctagggt atgaagatat tagattaaaa gaggatacag catatgatag
   114421 cacagtgctt gaccaaaaac gtttttaaaa cgaagacaag gaggtatata aatggctagc
   114481 agtttatata atttggctct agatttcagc aaagaattaa actacaccaa agctattatg
   114541 gctcgtcaag gtgacaaagg gattacggtg actgttaaac catttttaaa tggcttgcag
   114601 atggatacga gcggcggaac atttacttta aaaggaacta cgccatctaa ccgttacgta
   114661 gatagtgtcg ctactagtgt aactagtgaa gaagtcacat tttctcttga tggcacattt
   114721 atgagtgaag cagggtatta taaacactgc tatgtagaat atagaaaaga cgataaaatt
   114781 ttaacgacgc aagatatcat ttttttctca ctaggagtgt ctgacatttc gcaaggacaa
   114841 gctgatgaat atgtttcgca attggaagag ctgattcgaa agtataatga aacttttgat
   114901 gcttttatgg ctgaaattaa aggtagagtg gatagcttaa atcaacagat tactgattta
   114961 actggtcaag ctaaaacact acaagacaag ttagatgctc tgaaagaaga aatttctgag
   115021 ttaggtaact tgcaagtgat gtacagcaat agcatcaact tcgggaacta tgattatagt
   115081 gggaatccga atctaatgat aaatattaag ctggaagatt tgtcctccga acttacagga
   115141 tacagaaaac ctaccaacgt cacaatggaa aatggatgtt ttgttattga tgtaacaaaa
   115201 ttgacaggta gtcaagggta ttacattctt gatgtgccac gtgggctgga aggcaaacgt
   115261 tacacctatt ctgtggaagc gaaagcggac gttgcgacgc aagggatagc tattagacct
   115321 gtttatcaca acggaacagc gctagcggtt ttaactcctt ccagcgttgg atcgctaact
   115381 actactatga caagatacaa gttgaccaca aacccactga cagcccagca agtaaactct
   115441 actattcaag ccttccaaat ttatattgta ccatcccggt gcacagcaaa aaaaatctat
   115501 gtaaaaacca acatcaaaat ggaggaagga atagaagctt ctggtttcca gccaaatcta
   115561 ctcgatgcgc cgtattattt tagtaaagtg gctttgggtg agaatctaat taaaccagaa
   115621 tcacaacaac cagttactaa tagtaactat cttattaaca cctataacat taaaccaatg
   115681 gtaaaaggta agaagtatac catcacactt gaaggaacta agccagcaac acaggttttt
   115741 agaccatttt tcacacgagc aacaggagat gcatgggagg ttggtgactt acaaccagta
   115801 gaagggttaa ctgatgtttg gtctggaaca tttacagcag cagctgaccc acaccctacc
   115861 agcccacaag ttcagatttg tcaggtacca agcacaagtt taggaaactg tacaattaaa
   115921 tggttaaaac tagaggaagg cgacacacga accccgaata ttgagcaata taaataccta
   115981 ggaatcggca tgcgagactc aaacaatcca aaagattacg tttgggatct agcaccagaa
   116041 tatgtcgaag acaatcttgc tacagatgtt aaaatttctg aaatcacagg taaagcaaac
   116101 aattataccg atgggaaagt atcggagatt aattcgcagt tgactgcttc aattaatgaa
   116161 gtagacacca cagctaagga tgctcaaaca aaagcgaatg ctaatgcgac tgctataaag
   116221 agtacgaata gtagggttga tgagatagaa aacattatta cggccctaac aaaagaagaa
   116281 acatatttgc tacctgctag tatagtaaat ggcggatctc ttaaattcac aagtcgtggt
   116341 ggaatgacag tagctacagg atcatttaag ttggctaagg acatagcatt cggagaagtt
   116401 ttagttaatg atttgccaga ttcaatgatt aatattgata acaatgctat agggactgga
   116461 gctgtcacag gtaattctgt atcgcaaata tatgttgaat ctaatacgag aaaggtggtt
   116521 gcgaataccg ctatgaaaaa agatcaatgg tttacagttg gattttcgta tcacagtaaa
   116581 ttatctatat agatttagcg tactcattcg agtacgtttt tattttgcaa tgaaaggagg
   116641 ctagttggtt gaaagatgaa gcaatacaag acgttgtgga gagattagta agaattgaaa
   116701 caaaattaga caactacgaa tcacttagag aaaaggctga tagtgcaaaa gatttggcag
   116761 ataaagccta ttcagtagca ctaaacaatg cagaagacat caaggaaatg aagaataata
   116821 ataaatgggc ttggggctat atgattggct taggcattac gatcattggc tatttcttga
   116881 ctaaattgta aaggaggtga gaagaaatga ttttacccga taagtattat caagtcatta
   116941 aatggacggt tttaacagtt ttaccagcta catctgtttt agtagccacg ttaggaaaag
   117001 catatggatg gaatggaaca gatatgacag tactcactat caatgcagca gcaacatttt
   117061 taggcgttat cactggtgtg tcggcatata atttgaaaaa ataggaggaa aaaaatgaag
   117121 aagaaaatca ttttatcatt gagcctaata atggctcttt ttttattgcc aattaacggg
   117181 ttcgcctata cgatcaataa tgaatttaat ttaggtgcaa atgaaggtag ctcacaagta
   117241 gcaaataatc agtatatttt actgcatgaa acggctaatg aaacagcaac aggacgcaat
   117301 gaagcgcagt atatgcaacg ttcatggact agtgcttata ctgcttacat tgtgggagac
   117361 ggcggaattg tttatcaagt tggacaacct ggttatgtgc agtatggtgc tggttcgtat
   117421 gctaatgcca acagtcctgt gcagattgag ttacaacaca cacatgataa agcaacgttt
   117481 gagaaaaact ataaggcata cgttgaattg gctagagatt cagcaatgaa atatggtatt
   117541 ccattaacat tggatactcc ttataaccaa ccaggaatca aatcacattt atgggtaaca
   117601 caaaatattt ggggtgatca tacagatcct tacggttatc tttctgaaat gggcgtaagt
   117661 aaagaaaaat tagcatatga tttagctcat ggatttaccg atgaaaatcc aactacttca
   117721 gatgataaac cagtcattga tccaactaga gcaggtgcag caaatcctac gctgacagat
   117781 ggaacaaatt acgcccacat tgatcagttc ggagaaatcg aaaacgcaaa tttgcatgta
   117841 gctggatggc acattgctaa ctataaatac gagtatatct tcattatgga ctacaatact
   117901 ggaaaagaac tagctcgagt aagagctgat ggaatttata gaccagatgt aaaccaagct
   117961 tataatactt ctggaaatgt tggttatcat gtatctttca atatgcgtaa ttttcctagt
   118021 aagaaagtct atgtaatgat gcgggcaacg aatgatccag agggaaacac taaaggcggt
   118081 gcgcaagatt tccatgacaa acgttggtat ttaaatattc ctaaacgata aaaatagctc
   118141 ctcgttgagg agca
//
LOCUS       DACGMI010000002       105995 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.002, whole genome shotgun sequence.
ACCESSION   DACGMI010000002 DACGMI010000000
VERSION     DACGMI010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 105995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.002"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(270..1766)
                     /gene="lysS"
                     /locus_tag="IXT46_000135"
     CDS             complement(270..1766)
                     /gene="lysS"
                     /locus_tag="IXT46_000135"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAQ4946085.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1877..2881)
                     /gene="dusB"
                     /locus_tag="IXT46_000136"
     CDS             complement(1877..2881)
                     /gene="dusB"
                     /locus_tag="IXT46_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAQ4946086.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2882..3769)
                     /gene="hslO"
                     /locus_tag="IXT46_000137"
     CDS             complement(2882..3769)
                     /gene="hslO"
                     /locus_tag="IXT46_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAQ4946087.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3986..6097)
                     /gene="hflB"
                     /locus_tag="IXT46_000138"
     CDS             complement(3986..6097)
                     /gene="hflB"
                     /locus_tag="IXT46_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAQ4946088.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6187..6732)
                     /gene="hpt"
                     /locus_tag="IXT46_000139"
     CDS             complement(6187..6732)
                     /gene="hpt"
                     /locus_tag="IXT46_000139"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAQ4946089.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6732..8177)
                     /gene="tilS"
                     /locus_tag="IXT46_000140"
     CDS             complement(6732..8177)
                     /gene="tilS"
                     /locus_tag="IXT46_000140"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAQ4946090.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8297..8767)
                     /locus_tag="IXT46_000141"
     CDS             complement(8297..8767)
                     /locus_tag="IXT46_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAQ4946091.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8813..9238)
                     /locus_tag="IXT46_000142"
     CDS             complement(8813..9238)
                     /locus_tag="IXT46_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAQ4946092.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9305..9574)
                     /locus_tag="IXT46_000143"
     CDS             complement(9305..9574)
                     /locus_tag="IXT46_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAQ4946093.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9585..11180)
                     /locus_tag="IXT46_000144"
     CDS             complement(9585..11180)
                     /locus_tag="IXT46_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4946094.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGVALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11195..14716)
                     /gene="mfd"
                     /locus_tag="IXT46_000145"
     CDS             complement(11195..14716)
                     /gene="mfd"
                     /locus_tag="IXT46_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAQ4946095.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14733..15293)
                     /locus_tag="IXT46_000146"
     CDS             complement(14733..15293)
                     /locus_tag="IXT46_000146"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAQ4946096.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15646..16620
                     /locus_tag="IXT46_000147"
     CDS             15646..16620
                     /locus_tag="IXT46_000147"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAQ4946097.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16790..18190
                     /locus_tag="IXT46_000148"
     CDS             16790..18190
                     /locus_tag="IXT46_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAQ4946098.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18268..18990)
                     /locus_tag="IXT46_000149"
     CDS             complement(18268..18990)
                     /locus_tag="IXT46_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4946099.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19069..19575)
                     /locus_tag="IXT46_000150"
     CDS             complement(19069..19575)
                     /locus_tag="IXT46_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAQ4946100.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19698..21497
                     /locus_tag="IXT46_000151"
     CDS             19698..21497
                     /locus_tag="IXT46_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAQ4946101.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21565..23139)
                     /locus_tag="IXT46_000152"
     CDS             complement(21565..23139)
                     /locus_tag="IXT46_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946102.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23394..23903)
                     /gene="mreD"
                     /locus_tag="IXT46_000153"
     CDS             complement(23394..23903)
                     /gene="mreD"
                     /locus_tag="IXT46_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAQ4946103.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23907..24761)
                     /gene="mreC"
                     /locus_tag="IXT46_000154"
     CDS             complement(23907..24761)
                     /gene="mreC"
                     /locus_tag="IXT46_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAQ4946104.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24916..25554)
                     /locus_tag="IXT46_000155"
     CDS             complement(24916..25554)
                     /locus_tag="IXT46_000155"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAQ4946105.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25555..26205)
                     /locus_tag="IXT46_000156"
     CDS             complement(25555..26205)
                     /locus_tag="IXT46_000156"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAQ4946106.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26218..27117)
                     /gene="rsgA"
                     /locus_tag="IXT46_000157"
     CDS             complement(26218..27117)
                     /gene="rsgA"
                     /locus_tag="IXT46_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAQ4946107.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27282..29351)
                     /gene="pknB"
                     /locus_tag="IXT46_000158"
     CDS             complement(27282..29351)
                     /gene="pknB"
                     /locus_tag="IXT46_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAQ4946108.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29348..30088)
                     /locus_tag="IXT46_000159"
     CDS             complement(29348..30088)
                     /locus_tag="IXT46_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAQ4946109.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30101..31459)
                     /gene="rsmB"
                     /locus_tag="IXT46_000160"
     CDS             complement(30101..31459)
                     /gene="rsmB"
                     /locus_tag="IXT46_000160"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAQ4946110.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31459..32397)
                     /locus_tag="IXT46_000161"
     CDS             complement(31459..32397)
                     /locus_tag="IXT46_000161"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAQ4946111.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32390..32881)
                     /gene="def"
                     /locus_tag="IXT46_000162"
     CDS             complement(32390..32881)
                     /gene="def"
                     /locus_tag="IXT46_000162"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAQ4946112.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32896..35304)
                     /gene="priA"
                     /locus_tag="IXT46_000163"
     CDS             complement(32896..35304)
                     /gene="priA"
                     /locus_tag="IXT46_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAQ4946113.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35557..35862)
                     /locus_tag="IXT46_000164"
     CDS             complement(35557..35862)
                     /locus_tag="IXT46_000164"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAQ4946114.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35867..36481)
                     /gene="gmk"
                     /locus_tag="IXT46_000165"
     CDS             complement(35867..36481)
                     /gene="gmk"
                     /locus_tag="IXT46_000165"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAQ4946115.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(36968..37252)
                     /locus_tag="IXT46_000166"
     CDS             complement(36968..37252)
                     /locus_tag="IXT46_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946116.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37270..38160)
                     /locus_tag="IXT46_000167"
     CDS             complement(37270..38160)
                     /locus_tag="IXT46_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAQ4946117.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38180..38398)
                     /locus_tag="IXT46_000168"
     CDS             complement(38180..38398)
                     /locus_tag="IXT46_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946118.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38368..40068)
                     /locus_tag="IXT46_000169"
     CDS             complement(38368..40068)
                     /locus_tag="IXT46_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAQ4946119.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40335..41108
                     /locus_tag="IXT46_000170"
     CDS             40335..41108
                     /locus_tag="IXT46_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946120.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41189..41758)
                     /gene="thiT"
                     /locus_tag="IXT46_000171"
     CDS             complement(41189..41758)
                     /gene="thiT"
                     /locus_tag="IXT46_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAQ4946121.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(41824..41926)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(41932..42903)
                     /locus_tag="IXT46_000172"
     CDS             complement(41932..42903)
                     /locus_tag="IXT46_000172"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAQ4946122.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSIGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(42997..44370)
                     /gene="glmU"
                     /locus_tag="IXT46_000173"
     CDS             complement(42997..44370)
                     /gene="glmU"
                     /locus_tag="IXT46_000173"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAQ4946123.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(44873..45691)
                     /gene="purR"
                     /locus_tag="IXT46_000174"
     CDS             complement(44873..45691)
                     /gene="purR"
                     /locus_tag="IXT46_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAQ4946124.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFTKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(45858..46682)
                     /locus_tag="IXT46_000175"
     CDS             complement(45858..46682)
                     /locus_tag="IXT46_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAQ4946125.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46655..47335)
                     /locus_tag="IXT46_000176"
     CDS             complement(46655..47335)
                     /locus_tag="IXT46_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAQ4946126.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47358..48296)
                     /locus_tag="IXT46_000177"
     CDS             complement(47358..48296)
                     /locus_tag="IXT46_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAQ4946127.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48541..49392)
                     /locus_tag="IXT46_000178"
     CDS             complement(48541..49392)
                     /locus_tag="IXT46_000178"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAQ4946128.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(49546..52119)
                     /gene="mprF"
                     /locus_tag="IXT46_000179"
     CDS             complement(49546..52119)
                     /gene="mprF"
                     /locus_tag="IXT46_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAQ4946129.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52260..53066
                     /gene="proC"
                     /locus_tag="IXT46_000180"
     CDS             52260..53066
                     /gene="proC"
                     /locus_tag="IXT46_000180"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAQ4946130.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53145..54701)
                     /gene="rny"
                     /locus_tag="IXT46_000181"
     CDS             complement(53145..54701)
                     /gene="rny"
                     /locus_tag="IXT46_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAQ4946131.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55112..56161)
                     /gene="recA"
                     /locus_tag="IXT46_000182"
     CDS             complement(55112..56161)
                     /gene="recA"
                     /locus_tag="IXT46_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAQ4946132.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56270..57511)
                     /locus_tag="IXT46_000183"
     CDS             complement(56270..57511)
                     /locus_tag="IXT46_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAQ4946133.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(57751..58329)
                     /gene="pgsA"
                     /locus_tag="IXT46_000184"
     CDS             complement(57751..58329)
                     /gene="pgsA"
                     /locus_tag="IXT46_000184"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAQ4946134.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58538..59422)
                     /locus_tag="IXT46_000185"
     CDS             complement(58538..59422)
                     /locus_tag="IXT46_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4946135.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            complement(60200..61486)
                     /locus_tag="IXT46_000186"
     CDS             complement(60200..61486)
                     /locus_tag="IXT46_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAQ4946136.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61479..62747)
                     /locus_tag="IXT46_000187"
     CDS             complement(61479..62747)
                     /locus_tag="IXT46_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAQ4946137.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            62999..63460
                     /gene="mscL"
                     /locus_tag="IXT46_000188"
     CDS             62999..63460
                     /gene="mscL"
                     /locus_tag="IXT46_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAQ4946138.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63519..63965)
                     /locus_tag="IXT46_000189"
     CDS             complement(63519..63965)
                     /locus_tag="IXT46_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4946139.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64058..64303)
                     /locus_tag="IXT46_000190"
     CDS             complement(64058..64303)
                     /locus_tag="IXT46_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946140.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64418..64996)
                     /locus_tag="IXT46_000191"
     CDS             complement(64418..64996)
                     /locus_tag="IXT46_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4946141.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65073..65603)
                     /locus_tag="IXT46_000192"
     CDS             complement(65073..65603)
                     /locus_tag="IXT46_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAQ4946142.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65607..66467)
                     /gene="rlmB"
                     /locus_tag="IXT46_000193"
     CDS             complement(65607..66467)
                     /gene="rlmB"
                     /locus_tag="IXT46_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAQ4946143.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66460..66855)
                     /locus_tag="IXT46_000194"
     CDS             complement(66460..66855)
                     /locus_tag="IXT46_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAQ4946144.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(66852..68264)
                     /locus_tag="IXT46_000195"
     CDS             complement(66852..68264)
                     /locus_tag="IXT46_000195"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAQ4946145.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68261..68797)
                     /gene="cysE"
                     /locus_tag="IXT46_000196"
     CDS             complement(68261..68797)
                     /gene="cysE"
                     /locus_tag="IXT46_000196"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAQ4946146.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(69119..70579)
                     /locus_tag="IXT46_000197"
     CDS             complement(69119..70579)
                     /locus_tag="IXT46_000197"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAQ4946147.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(70749..71906)
                     /locus_tag="IXT46_000198"
     CDS             complement(70749..71906)
                     /locus_tag="IXT46_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAQ4946148.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(71940..73310)
                     /gene="radA"
                     /locus_tag="IXT46_000199"
     CDS             complement(71940..73310)
                     /gene="radA"
                     /locus_tag="IXT46_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAQ4946149.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73373..73900)
                     /locus_tag="IXT46_000200"
     CDS             complement(73373..73900)
                     /locus_tag="IXT46_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAQ4946150.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            74130..74936
                     /gene="proB"
                     /locus_tag="IXT46_000201"
     CDS             74130..74936
                     /gene="proB"
                     /locus_tag="IXT46_000201"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAQ4946151.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            74933..76180
                     /locus_tag="IXT46_000202"
     CDS             74933..76180
                     /locus_tag="IXT46_000202"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAQ4946152.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            76256..76600
                     /locus_tag="IXT46_000203"
     CDS             76256..76600
                     /locus_tag="IXT46_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946153.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(76717..77043)
                     /locus_tag="IXT46_000204"
     CDS             complement(76717..77043)
                     /locus_tag="IXT46_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946154.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(77658..78860)
                     /locus_tag="IXT46_000205"
     CDS             complement(77658..78860)
                     /locus_tag="IXT46_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4946155.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            78977..79492
                     /locus_tag="IXT46_000206"
     CDS             78977..79492
                     /locus_tag="IXT46_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4946156.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(79691..80137)
                     /locus_tag="IXT46_000207"
     CDS             complement(79691..80137)
                     /locus_tag="IXT46_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAQ4946157.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(80184..81662)
                     /gene="msr"
                     /locus_tag="IXT46_000208"
     CDS             complement(80184..81662)
                     /gene="msr"
                     /locus_tag="IXT46_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAQ4946158.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(82016..82645)
                     /locus_tag="IXT46_000209"
     CDS             complement(82016..82645)
                     /locus_tag="IXT46_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAQ4946159.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(82629..83093)
                     /locus_tag="IXT46_000210"
     CDS             complement(82629..83093)
                     /locus_tag="IXT46_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4946160.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(83580..84848)
                     /locus_tag="IXT46_000211"
     CDS             complement(83580..84848)
                     /locus_tag="IXT46_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAQ4946161.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(85079..85816)
                     /locus_tag="IXT46_000212"
     CDS             complement(85079..85816)
                     /locus_tag="IXT46_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4946162.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(85883..86452)
                     /locus_tag="IXT46_000213"
     CDS             complement(85883..86452)
                     /locus_tag="IXT46_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAQ4946163.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            86580..87452
                     /locus_tag="IXT46_000214"
     CDS             86580..87452
                     /locus_tag="IXT46_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4946164.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            87794..88666
                     /locus_tag="IXT46_000215"
     CDS             87794..88666
                     /locus_tag="IXT46_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4946165.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            88663..90621
                     /locus_tag="IXT46_000216"
     CDS             88663..90621
                     /locus_tag="IXT46_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4946166.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(90953..91804)
                     /locus_tag="IXT46_000217"
     CDS             complement(90953..91804)
                     /locus_tag="IXT46_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4946167.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            91927..92394
                     /locus_tag="IXT46_000218"
     CDS             91927..92394
                     /locus_tag="IXT46_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAQ4946168.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(92657..93139)
                     /locus_tag="IXT46_000219"
     CDS             complement(92657..93139)
                     /locus_tag="IXT46_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4946169.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(93239..94102)
                     /locus_tag="IXT46_000220"
     CDS             complement(93239..94102)
                     /locus_tag="IXT46_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4946170.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            94700..95575
                     /locus_tag="IXT46_000221"
     CDS             94700..95575
                     /locus_tag="IXT46_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946171.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(95720..95872)
                     /locus_tag="IXT46_000222"
                     /pseudo
     CDS             complement(95720..95872)
                     /locus_tag="IXT46_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(96140..97471)
                     /locus_tag="IXT46_000223"
     CDS             complement(96140..97471)
                     /locus_tag="IXT46_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4946172.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(97620..98333)
                     /locus_tag="IXT46_000224"
     CDS             complement(97620..98333)
                     /locus_tag="IXT46_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4946173.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            98508..99932
                     /locus_tag="IXT46_000225"
     CDS             98508..99932
                     /locus_tag="IXT46_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4946174.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSSEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            100231..100938
                     /locus_tag="IXT46_000226"
     CDS             100231..100938
                     /locus_tag="IXT46_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAQ4946175.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            100925..101248
                     /locus_tag="IXT46_000227"
     CDS             100925..101248
                     /locus_tag="IXT46_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAQ4946176.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(101337..102374)
                     /locus_tag="IXT46_000228"
     CDS             complement(101337..102374)
                     /locus_tag="IXT46_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4946177.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(102695..103678)
                     /locus_tag="IXT46_000229"
     CDS             complement(102695..103678)
                     /locus_tag="IXT46_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAQ4946178.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(104093..104863)
                     /locus_tag="IXT46_000230"
     CDS             complement(104093..104863)
                     /locus_tag="IXT46_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4946179.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(104856..105791)
                     /locus_tag="IXT46_000231"
     CDS             complement(104856..105791)
                     /locus_tag="IXT46_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4946180.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
BASE COUNT        29981 a        22626 c        18945 g        34443 t
ORIGIN      
        1 ttttgttatg tttttgaata aatattttct tctgtctttt ggacaagtaa taatatacca
       61 actaaattta gcttggtcaa cgaatttttt gtattttttc aagttttttt caataaacga
      121 ttattcataa cttttctttc tttatcgttc gttttcgtct tctttaatgt ctagaatagt
      181 cggcattagc ttttgaactt tcgttattat ttattccttt ctacacagca aaagctgcct
      241 aaggaattcc ttagacagct tttattcgat tatctcattg ttgggaatag caaaacatcc
      301 cgaattgatt gtgcatcagt tagcaacatt actaatctgt cgatcccgat gcctagacca
      361 ccagttggcg gcataccgta ttctaaggct tccaagaagt cttcgtctac accgtgagct
      421 tcgtcatttc ctagttcacg ttctttttct tgcgcttcga atctttctct ttgatcaatt
      481 ggatcgttca gttctgtaaa ggcattagca aattcgcgcc ccactatgaa tagttcgaat
      541 cgatctgtga atcgaggatc ttctggattt ttcttcgcta aaggcgaaac ttcgactgga
      601 tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa caaatgtttc aaagaattca
      661 ttgataacat gtccgacacc catagcttcg gttacttcta cattgtgttt ttcggctaaa
      721 gctaatgctt cttccaatgt catttcttgc cagaagtcta caccagtttg ttctttgatt
      781 gcatctacca tatggatgcg tttaaagtca ctttctaagt cgacagcttg tccatcatat
      841 gtgatttttg ctgttcctag tactttttca gctgcgttac ggataatacc ttctgtcaga
      901 ttcattacat cattgaaatc agtatatgct gtgtatgctt ctaacatcgt aaattctgga
      961 ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc cgatttcata aactttttcc
     1021 attccgccaa caattagtcg ttttaaatga agttctagcg caatacgcaa atataaatca
     1081 atgtccagtg cattatgatg cgtgataaat gggcgtgcgg cagctccacc tgcctcattg
     1141 tgcaatactg gtgtttctac ttcaatatag ccattgccat ctaaatagcg acggatttcg
     1201 ctgataattt ggcttcgttt cataaatcgg tcaaagcttt cgcgattact gattaaatcc
     1261 aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc catggtattt atctggcagt
     1321 ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt tgatagaaac ttcgcctgtg
     1381 tctgttttca tgatttgtcc agttacacca aagaaatctc caaggtctgc atgtttgaat
     1441 acttcatagg cctcatcacc tacttggtct tttcttacat aaatttgaat ttggccttca
     1501 cgatcttgta gatgcgcaaa tccagctttc ccttttcctc ggcgagtcat catacgacca
     1561 gctacactag cggtcaatcc catttctgct agttcttctt ttgttcttgg atcaaatagt
     1621 tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt ttccaaatgg atcgattcca
     1681 tcttcacgca attgttccat tttttgacga cgtacaagca tttgatcatt taaatcttct
     1741 acttgatgtt gttgttcctg tgtcacaaaa gttcctccat tctcatgtta atctctttcc
     1801 tataatgcca atgaaacaca aaaaaagcaa gccgaacttg gaatttcggc ttgaaaattc
     1861 acgaaaaact tagaaatcac aacgtttgtt tcaatagtac tttttccgct ttttctacaa
     1921 attgatccag caggtcattg atttcttgct gtttttctgt ctgattgatt gctactttca
     1981 ctttcgctgc tcgaggaatc ccttttaaat aataagccgc atgtgttctg aattctctac
     2041 aagctacttt ttctcctttg agatctgcta agcgttgtaa atgaagttta gctgtagcaa
     2101 ttttttcggc tggtgttggt tcaggaatca gttctcctgt ttcgagataa tgctgtgtgc
     2161 ggtgaatcat ccatggattg cccagcgctg cacgaccaat catcacaccg tctgcaccga
     2221 catagtcaag catccatttt gcatcttctg gcgttttgac atccccgttc cccataaatg
     2281 ggatcgtcaa atgttttttc acttctttca atacttccca gtccgctttt ccttcataca
     2341 tctgaacccg tgtacgtcca tgcatagcga tggcacttgc tccagctgat tgtgctgcta
     2401 atgcattttc tacagcaaag acgtgctctt catcccaacc aatacgcatc ttgattgtta
     2461 ctgggatatt tactgctgaa gaaacagctt ggaccatttc gtatactttc tcaggatcta
     2521 aaagccattt tgctcctgct tctgctttga ttactttatt tactggacag cccatattga
     2581 tatctattat atcggcagct gtgttttctt cgacaaattg agcagcttca actagactat
     2641 ctttatttcc gccaaatatc tgtaaactta atggatgttc tgtttcttca atgtggagca
     2701 tctctaaagt ttttttgttt ctgaaatgaa taccttggtc actgatcatt tcacatacga
     2761 ctaagcccgc accaaattct ttgacagtga ctcgaaatgc tgaatttgtt attccagcca
     2821 tcggtgcaac aacgacacga ttagggattt ccacattgcc aattttccat gtgtgttcca
     2881 cttaaatccc tcctaaggct tctttcttca atccatctaa ttcttcttcg ctatacttgt
     2941 atttgttatt acagaaagaa caaaccgctt ctgcaccgtg atcttcgtct atcattgctt
     3001 ggatttcttc tgcacctaac gcgataattg cttctgcaaa tttttctttt gaacagtcac
     3061 atttgaattg aacaggcatt ttttccaaaa tgttcaattc ttctgtacca agcaatcctt
     3121 tcaatatttc ttctggtgtc tgtccttcat ctaagagggt agagattctt ggtgtcgttt
     3181 ttaattgttc ttcgatcttg ctgattgttt cttcatcggc acctggcatg atttggatca
     3241 tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac caatacactc agtccaacag
     3301 ctgaagggat ttgttctgag atagcaagat agtaagtaaa atcttcagcg atttctccag
     3361 aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc taagtctttt gtgacagtaa
     3421 acattccttg tgttccaact gctccccgca catcgatttt accttcacta tttagaggaa
     3481 gactgagatg cggatttttg atgtaacctt tcacatctcc ctttccattt gcatctacta
     3541 caattcctgt tgctggacca tcgccttgga ttcgaacagt tagtttgtct tctcctttga
     3601 gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc caaagcagct gaggaggtgt
     3661 gccaagtatc atgacgtctt tgtgcctccg ctacggtatt tgttgcttga acggcgtatg
     3721 ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata atctttcatt tgttatgtac
     3781 tcctttttcc gtttttaaac tcatagtgaa tcatactagc aactactgct tttttcaact
     3841 ttggaatgct tcttttaaaa ataattcaga atcatctaga aaacaggaca tcaccctatt
     3901 tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg ttccggtttt cgggagtcat
     3961 atcagatcaa ttgacctata tttttttatt tgtattgatc gtctgaatga ttatcttctg
     4021 attgttgaga atctgaatca tgttctgctt tattttcctc attcagttca tgttttgctt
     4081 cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc tttttcttcc aaagcacgtt
     4141 ttgcttcttc aaaagttttc gcttcttttt cgcttggata atcatttgac tcagtacctt
     4201 caggcatcac accgtgttca aacaatgact tgattgcttt ggcatccaat gtttcgaatt
     4261 ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg agcttcgatg atttctcgag
     4321 ctttatcatg agcttccatc aagatttttc gtacttcttg atcaatctcg aaagcgactt
     4381 gttccgagta agcttttgtt tgaccatagt cgcggccaac aaacacttga tggtttcctt
     4441 catattgaac aggacctaaa cgatcactca ttccatattc tgttaccatg cttcgtgcta
     4501 gagctgtcgc ttgctcaaag tcattggaag caccagttga ttggacattg aagatgattt
     4561 cttcagctgt acgtccacca agtaagccta cgatttgttc aaacatatct tctttcgtca
     4621 tcaagaactg atcttctttt ggtaaagcga tcatatatcc gccggcgcgt ccgcgaggga
     4681 tgatcgttac tttgtggacg acccgagcgc gactcaatac taatccgaca atcgtatgac
     4741 cagcttcgtg ataagcaacc atttcgcgtt cttttttgct gattacgcga tcttttttag
     4801 ctggacctgc aatcacgcga tcttccgctt catcgatatc agaagcatcg attttctttt
     4861 tatttcttct agcagctact aacgctgctt cattcaagac attttctaaa tctgctccgg
     4921 caaaacctgg tgtctgttga gccacaactt tcaagtcaac gtcatctgcc atcggtttat
     4981 tccgtgcatg gactcgcaag attgcttcac gaccttttac atctggacgt ccaactaaaa
     5041 tctggcggtc aaaacggcct ggacgtagta acgctgggtc tagtacatca gaacggttgg
     5101 ttgcagcaat gacgattact ccttcatttc cgtcgaagcc atccatttct acaagcaatt
     5161 ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat accggcacca cgttgacgac
     5221 ctaccgcatc aatttcatca atgaaaatga tagctggtgc gtttttcttc gctgtttcaa
     5281 acaaatcacg aacacgactt gctccaacac cgacaaacat ttctacgaaa tcagaacccg
     5341 agatcgagta aaacggtact ccagcttctc cggcaacagc ttttgctaat aaggttttac
     5401 ctgttcctgg aggtccttct aaaagtacac ctgccgggat acgggcacct aattcaacaa
     5461 atcggcgagg atctttcaga aattcaacaa cttcaactag ttcttgtttt tcttcttccg
     5521 cacccgctac atcagaaaaa cgtacgcgat tagctttttt gtctgcttct ttggcttttg
     5581 atttaccaaa gttcatgaca cggccgccac cgccaccgcc gccgccttgt tgtcccatca
     5641 tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa gctaagcaat agggaaaccc
     5701 atataccgct gcttgattct tcttttactg ttgtagcaac tttgttttct tttgccagtt
     5761 ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat tgttgtgaaa tgggtagtag
     5821 tcgtatctgt tgaacctaag atagctaacc caccgctgtt agcgacggtc tgctgttctt
     5881 tgtattcacc agtgatctta tatacaccat ttgcaggctg cacttcaaat tctttgatct
     5941 tgcctgcttg tagttgttct gtgaattttg agtactcgat atctgacgat cgctggccgt
     6001 tattaccaaa aatgaaataa acgaccatta ccatcgctaa gattacgagg acataataca
     6061 aggcattttt catcatgccg ttgttctttt tgttcatagt tgccctccct aagcgtcaat
     6121 ttaatttaac agttttttat caatcctgac cattctattg taccataatt taattgagat
     6181 acagcattaa tttgattgat aaacactagg tttcaataca ccgatgtacg gaaggttacg
     6241 atatgcttct gcataatcca agccataacc gaccacaaat tcatttggta cgttgaagcc
     6301 aacataatct gcttcgatat ttactactct tccttcaggt ttgtcaagta gtgtaacaat
     6361 tttgactgat tttgctttgc ggtatttgaa aagatccact aaataagcaa gtgttcttcc
     6421 gctgtcaatg atatcttcaa cgatcaacag atcgcgacct tctacattcg tatctaagtc
     6481 tttgacgatt tttacttccc ctgacgagac tgttgcattc ccgtagcttg aaacatccat
     6541 gaaatccaat tccaaatacg tatcgataga acgaacgata tctgccatga atggtaccgc
     6601 tccttttaag acacctacta ctaggggatt ggtgttttgg taaatttctg ttaactcttt
     6661 gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag atcaaaattc tctcaatatc
     6721 cttttccaac atcaggttct ccttccaatt gcttcttttt gatatttgta aagaagtatg
     6781 tagtgtattt tatcagtttc ttcacgaata ctcaaatatg aaaaggcaaa aggtatcaag
     6841 ctatatatat ttcttttggc atctgtaatg atccaagcat gctgcctttg tgaattaggt
     6901 actttctgat cgataaaata tctagatact ttttttgtga gattctctgt taatttaatg
     6961 cggtctcctg cttttctttt ttcgacatac agttgcacat cagcaggaat ccaaatgtca
     7021 tgagaaaata gagaccatga atctgttgct ttgatgtccc ctgcattttc aggtttgacc
     7081 agaccaatcc attctgtttc attcaaatat attccttgtt ctggaatcag caacaagcgc
     7141 tggtcttctg tctggctagt tgcttgtttt tcttttttag agagtacaac aaaatgatac
     7201 tctcttttca gtatccaatt attgccaata ctgagttgcc attggctttt tttctgttgc
     7261 cactggtcta aaatcgactc catttgttgt tctttcaaaa taattcctgt ttttgagaat
     7321 gctttgtcga aaaaggagta aaaaaaatag tatcgttcag catctgtcat ttcttcaatc
     7381 atttctgcag aaaatcgaaa ttgttcctcc cactgttcga cttccttttc gatcaactgt
     7441 cccatatatt tttgaatgac ttggtctgcc cattggatct gttgcgaaaa ttgctggaaa
     7501 tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa ctaccaaatg acgaagccga
     7561 tttctctgga tatctaacaa ttggtttgtc tgatcctcaa agtaaacaag ctgcgattcc
     7621 gctgcataag tatataggtc ttctttgcta aaactcagca acggacgaat cagtctgccc
     7681 gtagcaaatg gttgtacttc tttgattcca gaaaaagtat ttaactgtcc cccacgaacg
     7741 attttcatta acaccgtctc gatttgatca tctccgtgat gagcagtcat caacgtgtca
     7801 tattgtcctt cttccatcac gcgagtgaat tcttgataac gaaagttacg agcttctgtt
     7861 tctatggcgg atttggctgg atcttcccaa atacttacat ataaagggag attcttctct
     7921 tcacaatatg agcgaagata ggcagcttct tctgctgatt cttctcttaa ttggtgattg
     7981 atgtggacga tacctaaaga aaaaccgatt tggcgttgca cttgtaaaag taaatggagc
     8041 aaaaccatcg aatcaacacc acctgatacc gctgctaaaa ttctcgatcc ttgttgccag
     8101 aatccttgtt cattcccgtg ccgaataaat gactgctgta atagcggtgc ttttttcccg
     8161 cctttttcaa cgttcatcct ttccacaccc tttcttccta aaaaaaagag agcgggaaaa
     8221 cgtctaaaac gacaattaac ctgccctctg ttgatactat gacccaaata gtcgcactat
     8281 cattatttgc ggctttttag ctgcgacgtc cgccacggcc accgcgcttt ccttctgtgt
     8341 ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa aaatgaactc atcaatgaat
     8401 cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa agattttttc tgtgctggac
     8461 gatttcggtt gtcacgggga tctttttgtt gatatttttt aggacggctt tcttctccag
     8521 attcagcagg ttgttcctgc gctttccgga tagatagtcc gatttttcca tcatcattta
     8581 ctgaaataac tttaactgtt acttcatctc ctacacttaa aacatcatgg atgtctttta
     8641 catagccatt tgacacttcg ctaatatgaa ctagacccgt ttttccagca cctagatcaa
     8701 taaacgcacc aaaatttgtg attcctgata cttttccttg cagttttgct cctacctcga
     8761 ttgacataaa aaaaatgttc ctcctaatta tttccctttt ttatattcct gcttattttg
     8821 cagttgtaga actagttgat tgatctgttt catttgtcga gctgtctgta tttgattcta
     8881 atataggata aactttttca ccgtcttttg agtaaaagaa tttgcttctg gcaagtttag
     8941 ctacatactc atcatctttc agcaatgaaa catcttggtg cagctgatca acgtctgcgt
     9001 tgacttcttt catttcagta tttgcttcga ctctcaattc gttcaattga tgcatccttt
     9061 gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat gaccaaagca ccaacaaaaa
     9121 ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg ttgttgctga aattcagcat
     9181 actttttctt tgcatattcc gtatctagcg cagcgatttt attgcttttt ttcgtcactt
     9241 ggattcgctc caatcttttt gattgtcttt ttcattatac caatatcgtg aaagcttgtc
     9301 taatctattt ctctagtgtt tctgtgcgat tttcagaaat aatttcgtac attttttgtg
     9361 catcttcttt tttggttgat tcatgtaatt ccgtaatttt cacttccaac gttttgttgc
     9421 caaactggac tttcaaaata tcgcctactt tgacatcact ggaagatttc gccaatttac
     9481 cgttgatttg aattcttcct ttatcagcta cttcttttgc tactgatcgt cttttgatga
     9541 ttcgggaaat ttttaaaaat ttatctaatc gcatatctta ttcctcactt tttaattttt
     9601 ttatttaatc gcaggatttt cttaccaaaa ggcaacatta gccattctcg tactgtaaac
     9661 agacgaagac gaatcactgc ataaatgaac acagaagccc cgatcccaac tcctatcacg
     9721 ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa atactatatt caatacacca
     9781 taatacagca gcagtactac tgtcatacaa agaaggctga acatcaactt ccgtccaaaa
     9841 tgccgttctt tccaaaaagc atttagctct tttgtttcaa ttcgaacaaa ataccaaagc
     9901 gtcacaccta atcctaaaag ggtagacagg cttgcacctg ctgttcctaa taaaccggtc
     9961 agaaaagaag tagtcaatcc ttttaccaat agtccccatc ctgcgccttt taaagaaggg
    10021 cgaaacgagt tcttgctttg agcaatactt tgataagctt ggatgactgc agtgaaagca
    10081 atggaaaaaa caaataatac aagcgctgca tttcccgcat aatctttaaa caacgcataa
    10141 ttgatataag ggagcagcaa ggctaatccc aaagacgcag ctaatgctaa agcggtcgtc
    10201 aatctaagat agattttggc tgtctgtaaa aactgacgat agatccggtt ggtcaaatga
    10261 cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg caatcactaa acctaattgt
    10321 actaaaggct gacctcgatc atagacccct tttgctatct tcgcaccgta ttctgacagt
    10381 ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga tcagctggaa aaagataagc
    10441 aatccactat aaatcgaaac cagtccgcct tctaccagaa aacgccggat caagggcttt
    10501 gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg ctactccatg aatcttttgt
    10561 tcatagtagt gaaggatccc atatgcgcat aaaccgccaa aaacagctcc actcattgct
    10621 gccgtccctg tttggtacac cgtccatcca agctttctaa aagcaaacgc actacagaca
    10681 atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa cagcagttgg ttccatcaag
    10741 aatcttcctt ggaaattccc tcgataaaaa gatagaccag gcatcagcaa aaaggtaaag
    10801 gaaactactt ggatcagcgg tttcaattgt atgtctccca tcatccaagc aatccagctg
    10861 ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc aaaatactaa gggataaaga
    10921 ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt ctgcaacgta ctttgatatg
    10981 aactgcggaa gaccggataa agctaaagtc attgctatcc cataaattgg ataaacttgc
    11041 tgataaacat aaaaaccttc gtcgccgact aagttttgga ggggaattcg gtaaagggca
    11101 cttaatactt ttgctatgaa agaagcaatc gtcaatacaa atgctccttg catgacgcgc
    11161 cgcatttctt tatgatccaa atcattgctc cttcctacgc tgacagatat ttttgctcac
    11221 gcaacgcttt gacaaacttt tggatttcct gaagccatac tgcttcttcc atttggttgg
    11281 ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc tagactggct tttagttttg
    11341 tcgctgtcag tgcttcgaat aactgttcca cactatagcg ttttgttcca actttactta
    11401 gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc taggagcgct cgatcgccat
    11461 ccattttgat ctgcccaatt gtcaagagat gtgctacttc ttctggatat tctccaaaac
    11521 ggtcgagcag atcatcttct agttcatcta gcatttcttg cgaatcaagt tcacgaattc
    11581 gtttatagat ctcgattttc tgccgttgat ctgccacgta tgtttcaggt agatacgcat
    11641 cgacaccgag gtcgatctca acagtggtct tctccacttg actattcttt ccttgtttac
    11701 gagaaacagc ttcgcttagc atttgagaat acatatcgaa accgactgca tcaataaatc
    11761 catgctgctg agcacctaag agattacctg caccgcgaat ggaaagatcc cgcatcgcaa
    11821 tcttgaatcc agatcccagt tctgtaaaat ctttgattgc ctgaagacgt ttttcactga
    11881 cttcgttaag gatcttctgc tgctcataca taaagtaagc atatgcgaca cggctgcttc
    11941 ttcctacccg ccctcgcaat tggtataacg tggataatcc catataatca gcgttctcaa
    12001 cgaacaacgt atttgcgttc gggatatcta ctcctgtttc aatgatggtt gtagtgacaa
    12061 gaacatcata ttgaccttca ataaattcaa aaagcgtatt ttctaattgc gcctctgtca
    12121 tttgcccatg agcataaccg atccgtgctt ccggaacgag ttcttggatt tcttctactt
    12181 tttgttcgat cgtttctacc cgattatata aatagaatac ttgtccacct cgtcccattt
    12241 ctcgatggat tgcttcgcga atagccccag gatttttttc cataacatac gtttggatcg
    12301 gataacgatt cgcaggcggt gtttcgatta ctgaaagatc ccgcacgcct aacatcgaca
    12361 tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa aacatccact tgtgcacgta
    12421 actgtttcaa tcgttcctta tgttttacac caaaacgttg ttcttcgtca atgatcagta
    12481 gacccaaatc gctaaattca atatcttttg acaaaattcg gtgggttcct acaacaatat
    12541 caacttgacc tgtacgcagt tgttcgatgg tttctttttg ttgctttctt gttctgaaac
    12601 gacttaatag cccgatattt acggggaaac cttcaaatct ttccagcatc gtttcatagt
    12661 gctgctgtgc caagatcgtt gttggaacta aaaaggctac ttgtttgctt tcctttatcg
    12721 ctttaaaggc cgctcgaagc gctacttctg ttttcccata accaacatca cctacgagta
    12781 gtcgatccat tggtttttct ttttccatat cccgtttgat ctccgctgca cttctcaact
    12841 ggtcatcagt ttcagagtag gggaaggcat tttcgaattc tttttggtag gcgtcatcag
    12901 gtccaaaagc atatcctttt tctgactctc ttgcggcata taatttgatt agatcgtcag
    12961 cgatatcctc gatttttgaa gagacttttc gcttggtttt cgtccattca cttccgccta
    13021 gcttattgat gcgaggcgct ttggcttcag aggcgacata tttttggatc agattcagtt
    13081 gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa aatagtcata tagtcttggt
    13141 gaacgccatc tacttctagc gtttccatcc caatgtattt cccgatacca tgattggcat
    13201 ggacaacgta atctcctgct tttaactcat tatagctttt caatcgctct gcgtttgtta
    13261 ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa aatttctttt tctgtgatag
    13321 ctactatttt ttcttgagga agttcaaaac cagcctgcaa agctccttca actaattgta
    13381 cctgtcctct gatcaatgca tttttttctg tttctactac taatatgtct tcatctcgaa
    13441 gcatttgttc tgctttgcgt attctgtcct ttgtcggaat aaagatcaca acagtctgtt
    13501 tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg catttgtccg aagaactgtt
    13561 gcatcgtccg atattgaaaa ttatggattg cttggaaacg aagatttccc atcccttttt
    13621 ggaagagtga gaaaaaggtt gtggtgaact tttccttctg cacgattttt tgtatatctg
    13681 ctgaaaatgt ctgctcagaa aacacccgca attcgctgat tttttgagtc tgccattctg
    13741 ccgcttccct ttcgatttcc cgatttgttt ccatgattcg ctgataatca tcaacgacta
    13801 gtaaactatt tgaagggaaa taatccaaga tcgtcacaga ttcttggtaa agaagatctg
    13861 agtagaattt tgcttcttct gtcgggacac ctgcttgcca gcttgaagtc agctgaccga
    13921 agtaatcttg caaaaactcg cggtctgctt cttctgtggt cgcagcaagc cgtttttcta
    13981 gcattttttg catttgctct attccatgtt ctagatcctc tggtccgtag acttgttcac
    14041 tcgttgggga aacccagatt tcttccgttt tttcgattga gcgttgtgtt tctgcttcaa
    14101 aataccgcat agaatctatc tctacatcaa atagttctac acgaacagga taggttgtcg
    14161 ttaacgggta aatatcgata atgcttcctc gaatactgaa ttctcccggt tttgcgacca
    14221 tctcttctcg tacatagccc atcaaagtca attggcgagg aagattttcc acgtctatct
    14281 catcaccaat atgccaattc aattgcgcct gtagccaagt tttcttattc ggcagtcgtt
    14341 tgtgcaaaga tgcgactggc aacaaataga tacctgcttt tttttcttga agtgcgttaa
    14401 gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa ggccatttca gcagaaagca
    14461 cttcatccac tggaaataaa tggatctgat cttgcggaat cacatgttgc agatcttctg
    14521 ctaactgatt cgcataatac aaatttggca tcagaataat catgttttta tttgttttct
    14581 taaacgctcg agcaaataga agtgttttcg ctgagcccgc taatcctgtg attagttgtc
    14641 taggcatttt ttcttctaaa ttgctgaccc attcttttac ttgcggatct tttccgacta
    14701 attgaataat atccattcct tttcctcctt cctcaattga atcgattcat cgcatccacg
    14761 aacgaatgcc cttctatgag atattcgact gctttaacag attgacacat gctttcttct
    14821 atcaaaggct gattttcttt gctgaaagga ctaagcacat gctggactac tgtttttttc
    14881 ccttctggcc tgccgattcc caccttgatt cgatcaaaga cattcgtatt caaatgggaa
    14941 ataatacttt tgataccgtt atgcccgccg gcacttccct tttgacggag ccggattttt
    15001 cccactgcca gatccaaatc atcgtagatt acgactaatt cctctggata aatcccaaaa
    15061 taagtcatta gtgggccgac tgcacgacca gattcattca tgaatgtttg tggtttgact
    15121 aaaaggatct tttctccatt atgaaaaaat tcggcaactt ctgcttcgaa cggatttttt
    15181 ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga ccataaagcc gatattgtgt
    15241 tttgtatatt ggtatttggt acctgggttt cctaacccga cgatcatttt catttttgtt
    15301 ttccacctaa ttctaaaaag cagcacaaaa ggctggactg ctaattagcg gtccagtcca
    15361 tcgagctttt ttctttttta tacttgtcaa tgcatagtat aacacaaaac aaggcgtttc
    15421 ggctaaaaga gaatcgttaa taaatgataa agaaattaaa aatttcttca aagtttaatg
    15481 aaataattga tatataaaaa tagtgaaata acgcacatgt aagctttttc atataataca
    15541 accttgttat ctgttatatt ttatagccaa atagcgtgac atggggcttg agaaatgtta
    15601 gcataagcat gggaaaaaac aaatcaatgg aaggattgat actaaatgac tgcagctgca
    15661 gaaaaaaaag atcatcaaaa agttattctt gttggagacg gcgccgtagg ttctagctat
    15721 gcctttgctc tagttactca aaatatcgct caagaagtag gtattgtgga tatcaatact
    15781 gctaaaactg aaggagacgc aattgacttg tctcacgctt tggcatttac ttcacctaaa
    15841 aaaatctatt ctgctactta cgcagacgca catgatgctg acttagttgt tattacagct
    15901 ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag taaacaaaaa cctaaaaatc
    15961 aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta acggtatctt tttagttgcc
    16021 gctaacccag tagatatttt gacttactca acttggaaat tctcaggttt ccctaaagaa
    16081 cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt tccgtcaagc acttgcggaa
    16141 ttagttgacg ttgatgcacg taacgtccat gcttacatct taggtgaaca cggagattca
    16201 gaattcccag tttggtcaca tgcaaatgtt gccggcttgc aaatctatga atgggtaaaa
    16261 aacaacccag aaatcgatga agaagctatg gttaacctat tctttggcgt acgtgacgct
    16321 gcttacacaa ttatcgagaa aaaaggcgct actttctatg gtatcgcagt agcattagca
    16381 cgtatcactc gtgccatctt agatgatgaa aatgctgttc ttcctttatc agtattcatg
    16441 aatggcgaat atggattgaa cgacatctac attggtgcac ctgctgttat caaccgtcaa
    16501 ggtatccaaa aagtaatcga aattccttta agtgacagcg agcaagaccg tatggctgct
    16561 tctgctaagc aattaaaaga aattctagat gaagcttttg ctaaactaga cgctgaataa
    16621 tctttgaaca tgacggaaaa catctattcg gtgttttccg tttttttatt ttatcaccct
    16681 tatggtttct aaattttttc ataaagtaga gataaccttc gtcttttcct ctaaattatg
    16741 ctatcatgag accgttccac cctaaacttt tacttaagga gttgtcgata tgacaagatc
    16801 ttcgcatcga aaaaaatcga aacatgttgc tttgctttca gttcttggtg ttctcttagt
    16861 gctgatcagc ttttatacct atcgcagtac atactacaca aagcattttt tgccgaatac
    16921 agaaataaat ggaataaatg tcagcaatct aacagtcgaa aaagcaaatg aaaaattaaa
    16981 agaagcttat tctgataaaa aactggctat taaagaagat ggaaaagtct ggcaggaagt
    17041 accaaaatcc gagctcggct acaaagatga tttcacttcg gagctttctc cgatcctaaa
    17101 tgaacaaaac ggatggactt ggggaatgac ttatgtctca gcggcagaaa aacaagaaat
    17161 agatcctgtc agtcaaaacc accaaaaact agacactacc gttcagacat tgacaactaa
    17221 gctgactgat ttgaacaaag accggacacc tactactgat gcaacgatcg aaaaagcagg
    17281 tgactctttc gttatcaagc ctgaagtcaa tggaaatacg atcgacgtcg atgctgcggt
    17341 caaacaatta aaaagtgcgg taaactctgg taaagataca attgaattga ctgaattcaa
    17401 agaaaaacca aaagtaacat ctgaagacag ctcactgaaa gaacaactcg catccatgaa
    17461 tgctatcgca aatgtaaaag ctacttacag tataaacggt gagactttcc agatcccatc
    17521 aagtgatatt atgagttggc tgacctacaa tgatggaaaa gtcgatttag atacagaaca
    17581 agtacgtcaa tatgtaacag atttaggcac aaagtataac acaagtacga atgacacaaa
    17641 atttaaaagt acaaaaagag gagaagttac ggtcccagtt ggcacttaca gttggacgat
    17701 ccaaacagac agtgagacag aagcattgaa aaaagcgatt ctggcaggcc aagattttac
    17761 tcgttcaccc attgtgcaag gtggcacaac cgctgatcat ccattgatcg aagatacgta
    17821 tatcgaagtt gatctggaga accagcatat gtggtattac aaagacggaa aagtggccct
    17881 tgaaacagat atcgtttccg gaaagccaac tacacctaca cctgctggag tcttctatgt
    17941 ttggaataaa gaagaagatg caactttaaa aggaacaaat gacgatggaa caccttacga
    18001 gagtccggta aactactgga tgccgattga ctggacaggt gttggtatcc acgattcaga
    18061 ctggcaacct gaatacggtg gagacttatg gaaaacccgc ggttcacacg gctgcatcaa
    18121 caccccacca agtgtaatga aggaattatt cgggatggtc gaaaaaggaa cgcctgtatt
    18181 ggtcttctaa caaaaataat atataaaaag aaagcacccg tacgattggt acaggtgctt
    18241 tctttttatt atctaacaat gtgctactta catttcagca gcagtaaaga cttctgaaac
    18301 atcatcatcg tcttctagct tatctactag acgttccaat tgctcttttt gttcctcatt
    18361 taaatcaatc gtcgtttgtg gaatcatcgt caattctgct tgcgccaaag tgaactcttt
    18421 ttccaactca tctcgtacag cagcaaaatc ttctggtgca gtataaatct cgaatacttc
    18481 aggagaagtt tgcagatctt ctgcccccgc ctctaataca tcctcaaaca tcgtctcttc
    18541 atcaacagtc aacccatcgc gttcaatagc gatatatcct ttgcggtcaa acaagtaact
    18601 gactgaaccc gtttctccca gtgatccacc gtttcgagta aaagctactc ggacatttgt
    18661 cgctgtccga ttacggttat ctgtcaatgc atggactaag attcctactc cacccggacc
    18721 atatccttca tacgtgattt catcgtaatt cgtttcatct acggcactcg tagccttttt
    18781 aatcgcccgt tccacattgt cgttaggcat atttgcagct tttgctttgt ccacaacaag
    18841 ccgcaaagct ggattcatag atggatcagg accgcctgct ttagctgcca tataaatttc
    18901 acgagaaagt ttctgaaaga ctttccctcg ttttgcatct tgggcatttt ttcttccttg
    18961 gatattatgc catttactat gtcctgacat gatttttcct cccttgttct tttgagaata
    19021 cacttctatt ctagtactat ttcacaaaaa aacaaagcca cagccaatct ataaacgctt
    19081 cttgaatgcc gcaaaaagca cacataatat cacagcagtc agagcaccga tcgaatccaa
    19141 catgacatct tggaacatag gtgttcgtcc accggtcatc atctgatgga attcgtccaa
    19201 acctgcgtac cctgttgctg aaagccaagc aaggatcgct gtcagccacc aaatttttag
    19261 cttggggaaa acacctaaaa acaagctgcc tcccaaaata aaataggtac cgaaatgtgc
    19321 gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc agatggtcga tactcaccat
    19381 acttccacca taattaaaac gtatacccgc taatgtgtct ttaaatggct gattaggcag
    19441 ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa gtttgagaag aactgtaaaa
    19501 taagattata acgactatca gtgcgattac taaataaata tttccgtttt tcatttgttt
    19561 ttttgaagaa ttcataagtc acctctgtat tttatcttag actttttttg aagaaacaac
    19621 aatcattttc atagagactt cttccataaa aaagtgctat acttaatttt gtattacaat
    19681 atgaagggag ttttttcatg agttattcat taaattggaa tctagattct attttttccg
    19741 gaggcagtca ttctgatgct ttgaaccaac ggatgaagca attggaagac caaatgaacg
    19801 agtattatca ccgcgtaaca aaatggtcac ctagttctga caatgcagag cagttaaacg
    19861 ctattcttca attgcaagaa acgattacga atggttttac ccaatgcagc agctatatta
    19921 ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa ggtcttatca ggcaagcttt
    19981 acgcaatgct gcctcgtctg caatcagccg aaactgtatt gtcaaagaaa tttgcagaaa
    20041 tatctgacaa tgattggaat cagatgcttt ctcaatcttc gtttgaaaca attgcttttc
    20101 gtttaaacga gattcgtcgt gatggctcac aattattatc agaagctgaa gaaaacatta
    20161 taaatacgct ttctttagat ggtctaaatg cttggagcag tcattatgat acgattgtag
    20221 ccagcatttc gattcccttc gaacaagatg gacaagtagt cgaattatct gctggacaag
    20281 ccttcaataa gatgatgggc gatccagatc caaaagtcag agaaacactt ttcgcagcat
    20341 gggaagaagc ctggaaagaa aaggcacccc tcttcacgga tactttgaat catttagatg
    20401 gttttagact ttctgactat gaacttcatg gtgtcacaga ttttctacaa aaaccattag
    20461 agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg ggatacaatc cagaaaaaca
    20521 aacaacccct tgttaattac ttgactagaa aagctaatct tttcggtaaa gaaaaaatgg
    20581 aatggcaaga tcaagatgca cctattattt taggcgattt gaaagaaaaa acctttagtt
    20641 ttgacgaagc agcagcattt attatcgaaa actttaacaa attcagtcca aaaatggcta
    20701 aatttgccca atctgctttt gaaaagagct ggatcgaagc agaagatcgt cctgggaaac
    20761 gtcctggtgg ttattgtact gagttaccag aaacaaaaga atcaaggatc tttatgacct
    20821 acagtaattc tgttaatgag gttgcgacac ttgctcatga actaggacat gctttccata
    20881 gcagcacgat gtgggattta ccttctttaa atcgcgaata tgccatgaat gtcgcagaaa
    20941 cagcaagtac attcgcagaa ctgatcgtag ccgatgctac attaaaagtc gcaaaaacaa
    21001 aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa tgctttagct atgttcatga
    21061 atatccattc ccgattcatt tttgaaaatc gattctatga agcacggcaa gaaggattag
    21121 tctcagaaga taagatcaca gagatgatgg ttgaggcgca aaaagaaggc tatcaaggag
    21181 ctttagctac ttaccatcca tatttctggg ctgcaaaatt gcatttcttt attgatgacg
    21241 taccgtttta taacttccca tacacatttg gctacctctt tagtttgggc atctatgctt
    21301 acgccaacca aaagggagca aattttgaag aagaatatat ccatttacta cgcgatactg
    21361 cctcaatgac gacggaagat cttgcgaaga aacatttgaa tgtcgatctt acccaaccag
    21421 atttttggca agcaggtatc gacatggtga ctgaagatat ccaaacgttc atggaattga
    21481 cagaagaatt tatctgattt ctattttatc acaataaaaa aagagttagt ccagaatggg
    21541 ctaactcttt ttgattaatc attcttacat gctgacagca aagtcagggg caaaccattg
    21601 aactgaacca acttttacgc tttcgcctgg ttgaggagca tggatatatt gtcctccgcc
    21661 taaagcaatc gctacgtggt aagttccgcc ttgtgacccc cagaataaca agtctccagc
    21721 ttttgcttga gaaactgaaa tttttgttcc agctgattct tgaggaactg tccaaccacc
    21781 gatgtcacga ccagttactt gcatgtaaac atagcgtgtg aaccctgagc agtcaaagcc
    21841 acttggatct ttaccgcccc aaacatatgg agtaccaata tatttgtaag cttctgctac
    21901 gattgctgca ccattcacac ttccagaagg agctggagca ggtgttacag gttttggttg
    21961 ttcaggtgtt ggtgttggcg ttggagccgg agtactactt cctgtgccgt ttcctgtatc
    22021 aacactttga tctgttgatg gtgttgtagg cgcaggtgtt gttgattctt ctgttgttga
    22081 agattcaggc actgttgttg attcttctgt tgctgaagat tcaggcactg ttgttgattc
    22141 ttctgttgct gaagattcag gcgctgttgt tgattcttct gttgctgaag attcaggcgc
    22201 tgttgattct tctgttgaag attcaggtgt tgttgattct tctgttgctg aagattgtgt
    22261 agctgatgat gattcttcag tcattgaaga ttgtgtagct gatgattctt ctgttgctga
    22321 gctttgtgca gtagatgaag cttgagtagc ttgtgcttca gcctctgctt gttcgcgtgc
    22381 ttctttttca gctttttctt gtgcagcttg ttgacgagct tgttctgcta gacgttgttg
    22441 ttcacgaata cgagcttgct ctgcttcagc ttctgctttt tgacggttca agtcagcttt
    22501 cttgtcttca gcagttgctt gttcagcagc taatgaagtt ttcagtacgt tcaaatcagc
    22561 ttgtttagat aaaagatcgc ctttttgaga ttccaaagca gcttggtttt cagctaattc
    22621 ttttagttta gcatcgtttt cagctttttt gtcttctaca gcttttttat cttgtttttg
    22681 ttgttccatc aagtcgttgt ttgcttttac catcgttgtc attgcttgaa cgcgtccaat
    22741 agcatctgct aatgaatcag cattcaatac agcatcgatg tagtttgagc ttgtgttgct
    22801 tacttgtgct tcgcgtgctt gtttttggat tgtatcttca cgtttttcaa tacgttcttg
    22861 taaatctgca atgtctttta ctaattgtgc agattcttga cgcaatgtat cttgttttgc
    22921 taataggtct tgtgcttgtg tgttgatttc agaaacttgg ctttctaagg catcgatttg
    22981 tgattgtgca tctgcttgtt gatttttcaa gtctgcaatc ttttgatctt gctgttgtat
    23041 ctgagaatca aaatcgtccg ccgcggcagc gatcggtgat gctacggcag tcaaggtcat
    23101 tgaacatacc attactgctg atattaaact ctttttcact cttcattcct ccgactggct
    23161 taatttaata aatatctaaa tatatttaag tctttcttaa cgatataaaa attgtaccat
    23221 agcagtgtgt caacgatata atagttatgt tacaaaaatg tttcaaaaca acttttaaaa
    23281 atgacaaaac tgttcgtttc agaaaatgat catgaaaaag ccgcgttaag tctagcattt
    23341 cttaagataa caacgattct ttttcgcttt cgacctaaaa ataaaaaaag aaattattca
    23401 tcactgaata atttcttaaa gggaaaaatg aataatacaa atataatcat gttcaacagc
    23461 agtgtaggtc ctaaaaacct tgtaataaaa tacgtgttat ttactactgc taatttaaaa
    23521 atcaactgga ccaccatcgt aaacaattca taacccgtga caaagatgat catactgaaa
    23581 aattcagtaa agatgttgac atggataacg tctttcatta catacatcaa ccatacaatt
    23641 aaagggagag ctactgcata gataccgata acgccaatat agtaagcgtc atagatagcc
    23701 ccgagaacaa tcgtggtaat cagtaaataa cgtttttcaa acgccatact gcaacataat
    23761 aatgccaata tcagaaagtg ggcatttgac atataggtgc ctttcgacca ctcccctagc
    23821 attcttgtta aatgaccatc tatcaacatc aaaaagaaca aaacgattgg cagatagtac
    23881 ttcattgttt ctttcttcaa catggactaa tcctccgcta gccgttggac aatcgtcaca
    23941 actgacacgt catacatttc tgcataaggt ttcacataaa cttcccgatc cagcccataa
    24001 ctatctggtt tcgttttaat aaccgtaccg atcggcaagt tagctggaga attccctcca
    24061 agaccggatg tctggacaac atccccttct ttgatatccg tatcaccagt taattgggtc
    24121 accactaagg catggagctt ttcatcatag tttttaagca aaccaaacgc ttcgccatta
    24181 gccgaagata cccgtactgg aaaatgattg gagctttcat tagaggatga cagtaattcg
    24241 attttagacg aagccgtatt gacctcgatc actcggccaa tcaatccttt ttgcgacatg
    24301 actgccatat ttgcttcgat accgtcttta gaacccttgt ctacgatcag catgtcctgc
    24361 caactgtcag gcgaacgagt aatgacattt gccgttactt tttcgtaact agtcagcgtc
    24421 tgattcaact caagttcttt tttcaacgct tcgatttctc tctcgtaatt cttgttttgc
    24481 tgtgaaacgt catcatagct atcgattttt tcttttagcc gctcattttc ggcataagtt
    24541 gaaaaaagat tatggacaga atctactcca tttcgtaccc accgtactgg ggcagagatt
    24601 gttttatcaa ccattgcaac actgtcatta acgatggatt ggaagaaatt gggctttcct
    24661 tcattcgctc gctgcgcagc ggtcacactt agtatcgtca ccacgatgat aacaataacc
    24721 aaggtaataa taatattttt attaggattg aacttcttca caaagacacc tcgaattaat
    24781 tagactcttg tgttcaattt tatcactaaa tgccgtgaaa caaaaggtaa gttgctcctc
    24841 ttaagctttt ttttagcaaa taatagattc tgtcattttt agcctgaaag acaaattttt
    24901 ttatttgttt atggatcaat ctttgctttg aataactgca atcataccat ctgaaaaaga
    24961 aaattctgcg gtatctgaaa gaaattcgtt acttgcataa gatgtcggat attctacttc
    25021 tttattttcc aatacatact tgctgccttt taatgtaaga ttcgagacgg gagtcaagca
    25081 gcaataagct aaatacttca tatctggtat ctgtcttact atatgctctc caggcaaata
    25141 ataagacaaa taattttgac aatctctgat aataagctga tgggcaaagg gtttgaagcg
    25201 aggttccata cctaaccaga gattggctaa aagatgatcc aatcttccgc ccgtagctcc
    25261 aatcaaagtg acttccgctt gcgggtaacg ttcaaatgtt tttaagatac ctaactgtgt
    25321 atctgtatcg tctttttctg caggggaacg ggtatactct ttggcttttg caaatacttc
    25381 cttctgctct tcgttcgaca atgaatcaaa atcacccact gccagatcta ctgggtagcc
    25441 tgcttgaagc aggtacagcg caccacggtc tatcccgaca taggcatcgt atttggacag
    25501 cagagactgc ggccagtttt gcggattacc tccagcagct aataaaattt tcatttagtc
    25561 taatgcctct tttaatcgtt cgatttgtcc gactggattt tcggctccat agatatatga
    25621 tcctgcaacg aagacatccg cccctgcatc tttacagatt tttgctgttt ctggaacgat
    25681 tccgccatct acttcgattg cataagtcca attgttctct ctacgtagat cagcgagttc
    25741 cgtaattttt tctactgttt cttcaataaa gctttgtccg ccgaacccag gattgacagt
    25801 catgactagt acttgatcag ccaaaggcaa aacatgtttg atcatggaga ctggtgttcc
    25861 tggattgata actactccag ctttaactcc taagcttttt gtcatttgaa gtgcccgatg
    25921 aatatgagga gttgcttcga cgtggacagt aatgatatct gctccagctt ttgcaaatgc
    25981 tggaatgtag ttttctggat caacgatcat cagatggacg tctaacggta atttagtaac
    26041 aggacggatt gcctgaacaa tatttggccc taatgtgata tttgggacaa attggccatc
    26101 cattacatct acgtggatgt aatctgcgcc tcctttttcc actaactcaa tgtctctttg
    26161 taaattggca aaatctgcac tcaaaatgga tggtgctatc ttcattcttg tttcctccta
    26221 ttttcgttta ccttcttttt ttgcatacat tggttttctt ttttcgattt cttgtaagaa
    26281 ttgcaaataa ttgtcgtaac gtgtctgtgc gataccacct gtttctactc tatgttttac
    26341 ttcgcagcca ggttctttag catgcatgca ctctctaaat ttgcaatgga cagaagcttc
    26401 tacaaattca ggaaattgtc tcggcagttc tcctgcttca attgtcaaaa agtcaatcga
    26461 gctaaatcct ggtgtatctg ctactaaccc gccatagata ggaatcagtt ccacatgacg
    26521 tgttgtatgc cgtcctcttc caagtgcatc agaaatctct cctgttgcta aattcagttc
    26581 cggtgatatt tgattcagta gcgtcgattt tcctgctcca gactgaccca taaagaccga
    26641 tagccgttct gggaagtaac ggatcagttc tgtcgtatca cccgtatgat tgggtacaat
    26701 caccggatag cctattttag tataggtttg cttgatctct tcgatttttt ctgggtcgtc
    26761 tgacaagtcg gtctttgtca aaaaaataat cggttcgatc gactcgtatt ccaaggtaac
    26821 tagaaagcgg tcaagtagat tataagaaaa tgcaggctct acgatacttg tgacaatgat
    26881 tccaagatca acatttgtga ctggtgggcg aactaattga ttttttctcg gcaagatttc
    26941 cagaagatag ccgtctgttt gattttcact ctcaaagatc acctgatctc cgacaagcgg
    27001 cgtgattttc cgattccgga aatttcctct tcctcttgtt tgataggtct ctccgtttgc
    27061 gtatacatag taaaaaccgc tgattgcttt tctgatttgt cctttgataa gtgccacctc
    27121 cgtttttgtt tattttacca tacgaagagg aaagtaggtg ttattccatg caaacttctc
    27181 aaagtatatg gcttgaaaat tgatcaaaag agatagaaac acaaaaaaga gaatgcaaca
    27241 aatcaatgtc gcattccctt ctgatatatt ttattcagca cttattttga actttctgag
    27301 gtgctagctg atgaacttgt ggagctggaa gattcttctt ttgaagagtt gcttgtgcta
    27361 ctggagctac ttgagctgct agaactgtct gaagagtctt tttcagaact agaagacgct
    27421 ggatctggtc ctttagagta aattacgttc acaaccattc ctttggtaat tgtcgttcct
    27481 gcccctggta ctgtacgaat cactttatct ttatccaccg tgtttgaata ttcggaagtc
    27541 tcatgcccga tatattctgc accgacacta gctaaataac tttgtgcttc gctttttgta
    27601 tagccggaga tatcattcaa tttaggctct gttccttggc ttacgacaaa attgatgtaa
    27661 gtttcttctg ctacaacttc acccgaggct ggatcctgac tgatgatcga acctgatggt
    27721 acagtgtcgc tatagtcata agtagcacta atattattga tattgaatcc ttgtgtaaca
    27781 agccaattac gaacagtttc gtagttttct cctacatgac tactcaaagt cactgtttct
    27841 ggtcctttgc tgactgtgaa agtaatcgtg tctgttttag gatcgacttc tgtatcttct
    27901 gatggagatt gcgaaatgat cattccgctt tctacctctg aactgaattc ctcttctttt
    27961 tgaatcaagt cagcagaaaa ccctaattct ttcaaacttg cttcggcatc ttcataactt
    28021 ttaccactgt aatcatctaa tttgattttt ttcgtgccgc tactaatata cagagtgact
    28081 tcgcgttttt gcttgactgt cgttcccgct gccgggtctg tcttcactac attaccttct
    28141 tcgattttgt catctgcaat ttcttctgtt tttgttgcta cttctaattt cgcttttgcg
    28201 agtgtttctc tagcagaagc ttcagaaaga tcagaaacat caggaacaac aacttctcct
    28261 cgcccgccag aagcaaagaa tacagctgtt ccgattccta aaacagcaag aatagctaat
    28321 aggatcagcc accatttttt ctgtcctttc tttttaggat caggcagaac ttcttcctcc
    28381 tctggtaagg tttcgttttc tggcttgtct tttggcagag gcatagattt gaatgaatca
    28441 ggcattggtg catcttccgt aaggggtgtg ataacttttg tttcattatc catcacatga
    28501 ggctgccatt tttcttcgtt tgcacgagct ggtgataata ctgtagaaag atcatcagac
    28561 atttcctcgg ctgacttata acggtctgca ggttctttag ccgttgcccg taaaatcacg
    28621 ttttccagtg cttgtggcac atttggatca agtgctttta tagatggaag atcatcttga
    28681 aaatgtttta aagcaattgt tacagcagat tcaccatcaa acggtacgct acccgtcaac
    28741 atctcataaa ggatgatccc taaagcataa atatctgact gcttcgttgc catacttcct
    28801 ctggcctgct caggggacag ataatgaaca gatcctagca tcgtattcgt ctgcgtgatc
    28861 gatgtttcag ataaagcgat agcaatcccg aaatccgtga tttttacaac accttcatta
    28921 tcgatcagta cgttttgggg tttcaaatct cggtggatga tttgatggtt atgagctaaa
    28981 gaaatagcag aaaggatctg ctgcataata tttactgctg tttcataagg aacaggataa
    29041 tgtgtttgga tatatcgttt caagtccatt cctttgacgt attccatcac cagatactgc
    29101 atgttgtctt cttcaccaac atcgtaaaca ctaacaatgt ttggatgaac gagttctgtt
    29161 gctgctaaag cttctctctg aaatcgtcga atcgcagtct ggtcattttg aaagtcaaat
    29221 cgtaagactt taactgctac atcacgatcc aagattaaat cgtgcgccaa aaatacattt
    29281 gccataccac cgctaccgat atttccagtg atttgataac ggccatttaa ttttttgccc
    29341 aactcgatca tacactgtcc tccttatatt cgataagaag aacggtgata ttatccgctc
    29401 cgcctgcttc attggcacga tcaatcagct cagttacttt atgagacaat gggccttctt
    29461 gattgatgat cgttcctatt tcttcttcag acagcatgtt cgtcaagcca tctgaacata
    29521 acagcagtcg atcttttagt tgccaaagat gagtagaaac atctacttcg actgttccag
    29581 gcatgccgac agaacgtgtt aaaatatttt tccttggatg gttcactgcc atttcttcgc
    29641 tgatttctcc tgatttgact agttcattga ctaaagaatg atcctccgtc aattgcatga
    29701 ttttatcttc acgaatcaaa taagctctgc tatccccaac attggcaatc gtgaaccagt
    29761 catctgacag agcggccgct acgattgttg ttcccatacc gttatattcc ggctgttctt
    29821 gtccacgctg ataaatcagc atattttctt cttgaatcga ttgaatgaac cattgggcga
    29881 ttttttcatc gtcaacagct tcttgttttt cccaagcttc gcctagattc gttaccgcca
    29941 tctgactggc aatgtctccg gcacgatgac cacccatccc gtctgctaat acagcaagct
    30001 tgagacctga acggctggta aatacactgg catagtcttg atttgtgtta cgtcgtcttc
    30061 ctacatctga ttgatattca atctgcattt tttcacctca ttactttttg cgcaaacaac
    30121 aaatgaaaaa tccatctgtg taaaactgat gcggatacaa agtcaacatt ttctcttcga
    30181 ttgatgattg tagcatagga ttggtcaaaa catcaatcct ctcaaaatca gggtgtcttt
    30241 ccaagaaagc agaaacaacg tcttggtttt cttcttttaa gatcgtacaa gtgctataag
    30301 tcagaatacc ggaagacttt aaagttggtg cgcagctttc taaaatttcc aattggattt
    30361 ttggtaaatt cgctaattca tccggctgtt ttttataacg aatatctggt tttcgccgaa
    30421 gcagcccaag acctgaacaa ggcgcgtcta ctaaaatccg atcaaactgc tctgcttcga
    30481 actgtttact gacttctcta gcatccatct tttgagcgta gacagcagaa gagacaccta
    30541 gacgtgctgc attatcttca atgagtttga ctttgtgttc gtgtacatct aaagcgacca
    30601 cttctccacc gcatgacgga tctaaaaaag aagcaatatg cgtcgtctta cctccgggtg
    30661 ctgcacaggc atctaagaca tgatgttcag gctcgatttg catagacggc gctacaagca
    30721 tcgaactttc atcttggatc gtcatgacgc catcgtggaa caatgagcta gaagctaaat
    30781 gccctttttt cgctactata ccgtatggac tgacttggct tttttcagct gtgatctctt
    30841 cttcttgcaa aacagtgatg gcctgatctc tggaaagtcg gcgtgtatct actcgggcac
    30901 tagcatggct aggctgatat agcgataaac cgagcttttc agtttcttcg tatccgattt
    30961 gatccaccag tcgtttcgtc atccatagag gcaggctgat tttgacagaa agtctttcga
    31021 taggatcagc aatgccttgc agatctggtg ctccttgacg ctgataattc ctcaagacac
    31081 catttacaaa tttccctgtc ccaggatttc cttttacttt tgcgatttcg accgcctcgt
    31141 ttaaaatagc atgtgcaggg actttatcta aaaattctaa ttggtataca gaaagataaa
    31201 gaagcgtctt gacccagtca tccacttttt ttgctttagc gatcaatggt gcaacgtaaa
    31261 attccaatag tcgctgatgg ctaatcgtac catagatcaa ttctgtaaat aaacccacat
    31321 ctttttgatt tagctcgctt tgtttgatca tctcattcaa caaaagattc gagtaggcgc
    31381 cacccttgtt cactcgctct aatgtcagta atgccatata tcgtactgat tttttcattt
    31441 ttttagggat ttttttcatt atttcacctg ctgaccaatc tgaacttgct gaccgcttcc
    31501 gttaaggaaa tcatgtacgg cctgttttcc tttaccagct ggctgtaatt cattgatggc
    31561 taagacggtc tgtttaccgc aagcaatcca tagatttttt ttgtctttcc ggatgatcgt
    31621 accaggtgct ttgtctgtag tttctgccaa tacttcaacc gataataatt tccagcgtat
    31681 gccctcatag gtcgtgaatg caattggcca aggacgcatt ccgcgtactt ggttgtcaat
    31741 ttcttctgca gttttatgcc aatcgattgc ttcttgttcc cgtgtgatgt ttggcgaaaa
    31801 agttgcttct gactcgtctt gaggtactgg tttttgtcca tccaaaatat tgggcaatgt
    31861 ttctagcaat agctttcttc ctaaaaggct aagcttttca aacatcgtcc ctacatcatc
    31921 ttgtttagtg attggtatgc tttcttgcgc atagattccg cctgcatcca tttttttgat
    31981 catttccatg atcgttacac cagtttcttt ctccccattc atgatggcat aatgaacagg
    32041 cgcacctccc cgatatttag gaagtaaaga agcatggaca ttgattgccc ctaattttgg
    32101 tacttgcaat aacttttcag gcaagaattg gccaaatgcc gcagtgacga tcacatcagg
    32161 caccaattca atgatttctt ccatttctgg cgaaccggag attttctctg gctgcagcac
    32221 acggataccg tgcttcagag ccgcttcttt taccggtgtc ggcgtaatta ctcgtttccg
    32281 cccaactgga cggtcgggct gtgttaccac tgcctggatc tcgtaacctg attctatcag
    32341 cccttcaaga atcggcacag aaaaagcagg tgtgcccata aatactagct tagtcatcaa
    32401 gatgttcctc catatattct tcaagttctt cttccgggat ctgctgtatc attttctcaa
    32461 tgaacaagat accgtctaag tgatcgattt catgctggaa ggcacgggct aaatagccaa
    32521 aagccgtcac ttctatctct tctccgtctc gatcataata acgcacggtc acttcatctg
    32581 ctcgcttgac cgttccatag acatgcggaa tactgagaca accttctacg tcaaggcttt
    32641 caccttttgc ttcgatgatt tctgggttaa tcagttcaaa tttctcgcct tcatctactt
    32701 cgatcacagc aattctcttg ttttgtccta cttgaggagc agcgatccct attccgtcat
    32761 tcgcaatcat tgtctcatat aaattgtcta ataaagcgat tgtctcgtcc gtgattacat
    32821 cgattggctg agcagttctt tttaatttat cattagggtg gatcaatata ggatagcgca
    32881 taatttggcc ctttcttaaa taaagtttaa tggttcgttg tcaattgcca caaaaagacc
    32941 ttgtcgctgt tctttctggc ttccattcaa aatttcatcc aaaacatgag gaagattcgg
    33001 ttcatgttta tatttgatga ttagttgata ataatatcgg tttttcactc tcaaaatcat
    33061 gctgggcgtt ggccctaata gcaagctttg agggcttaac acttctttta gctgattggc
    33121 aatctgaaag attttctttg ccgctacttg ttcttcagga tggctggcgg ttattttcac
    33181 agtaaagtaa taaggaggat agcctccacg atgccgtaca tgcatttcct gctgataaaa
    33241 ctgctcataa ttttgttttt tagccaattc tatggcgtaa tgttgaggat tgaatgtttg
    33301 gatcacgact tcgcctgctt tttccgctcg ccctgctcgt cctgaaactt gggtaagcaa
    33361 ttggaatgta tgctcactag aacgaaaatc cggtaaattc agggaggtat cagcattcaa
    33421 caccccaact aatgtcactt ctggaaagtc caaaccttta gcaatcattt gtgtccctaa
    33481 taatatatct gcttcttttg caccgaattt ttgtaaaatc tgttcgtgtg ccccttttct
    33541 tcgagtggta tctacatcca tacgcaaaat cctagcttgc ggataaagtt ctcggagttc
    33601 ctcttctact ttttgagtac ctgttccata gtagcggatt ttattgccgc cacaattagg
    33661 acagcgattg ggaataggtt cttcatgtcc gcaataatgg cagcgcattg aacgtgtatc
    33721 catatgcagt gtaagagaga tatcgcaatt aggacatgga agaacaaatc cacagtccct
    33781 acacatcaca aaagacgaat atcctcgacg attgagcagt aggacagttt gttctttttt
    33841 gtctaatcga ttttgtattt tttcctgcaa attagcagaa aaagtagagg tccgatgatt
    33901 ctgaaactct tcacgcatat ctacgatctc aatagctgga agctgtgcag ctgctttggc
    33961 tcggtggttt aactgcaata actgataaac gcctttttga gctcgtgctc ttgattctaa
    34021 agagggcgtc gcgcttccta gaactattgg gcaatgatga tatttactgc gccaaattgc
    34081 tagatctctc gcatgataac gcggtgtctc atcttgtttg taacttgatt catgttcttc
    34141 atcgataatg atcagcccga tatttttcag cggggcaaaa atagcagatc gtgcgcctac
    34201 tactacttgc gcttcttccc gctcaatctt gcgccattca tcatattttt caccttggga
    34261 aagtccgcta tgtaagaccg caactgattc tccgaagcgt cctttgaatc gctcgaccat
    34321 ttgcggagtc aatgcgattt caggcactaa cataatagcc gttttatttt ctgacaaaac
    34381 atcagcgatt gcctgaagat atacttctgt tttcccgctg ccagtgattc cctccagcaa
    34441 aaagacctga tctttttgct gctgacctgc tgtgatgatt tgttcgacag catttttttg
    34501 ttctgcattc agttccaatg ccgtcgtttg gtcaaatact cggtctttat aagggtcgcg
    34561 ataacgttct gattctataa actccagcca gcccttttct tttccttgat tcaagacagc
    34621 agtactgatt cctttatttt tgaaataagc aattggttct tcttggctca gttcagataa
    34681 acacaaaaga agttcttttt gtttcttggc attttgccgt aattttgccc attcttcttc
    34741 gatttgcttt tcagttaaca aagaacggac caaacgaatc gtttttactt tatttcgtgt
    34801 atggacttca tatttgatat ctactaattg ctcttggcgc cagcgaatca attgagaaag
    34861 gctgccttct tcttctgctt ccttccagga aatcacttct cgctgatcaa acaatacctg
    34921 aacttctggt gtgtctgcca aaggatagat caatttatca tattctgctt tcatcacact
    34981 cggaagcatc gtttgtagac aagtgatttt gaatgcgtaa gtaatttttt tcatataatc
    35041 agctaatgaa agtaattctt cattgaccac cggagcaagg tctagcaaac gaataactgc
    35101 cttcaaagat ggattagctg attcttctga tttttggata gccataacaa atccttggac
    35161 atgacgattg ccattaccaa aagggacttc tactcgcatc ccgacttgca aagctgtttc
    35221 catttcagag ggaaccaaat aagtgaatgg ctgatcggtc tgcatagtag gtacgtccac
    35281 aatgacttca gctgttaatg tcatggttcg tttcctcctt tttttgtctt ttcttatcaa
    35341 gcgacaaaaa gttccttgcc tattttacta gagatcgatg gatttgtctt atcttctgcc
    35401 aaatcctaac aaaaaattaa cagcagataa gaaaaaaaag aactgtgtca aaaagttcag
    35461 acacagcctt ttctaccaga caataagtgg cgaatgtttg aaaaggaaac agctgggttt
    35521 gcttttcttt ttagatgttc gctctatttt tctttattac attttttgct cttcacggat
    35581 acgtgattcc aattcgtgtt gttcacgctc tttttgtgct tgacgttcct cttcttccat
    35641 cttcaaacgt tcacgtttta attcaggatg tggatcattg actacatttc ctgcatcgat
    35701 ttcttctaaa gcttgaccga cgctttttac tgaatcaaaa gaatctagag taggctgtgc
    35761 acttgcatcc aattcatgcg cgcgtttact tgctaaaatc actagagaat attttgaatt
    35821 tacacgatct aatagtgagt caattgaagg ttttaacatc ataagactac atctccttta
    35881 acattttaat atatttaccg attacgcgat ctactcgaaa atgttcactg gcaataatgt
    35941 ttttgattcg ttcaactgct agcggcactt catcatttac aacagcatag tcgtaaagag
    36001 ccatcatttc gatttcttct tttgcaactt tcattcgttc ttcgattact tcatctgcat
    36061 ctgttcctcg gcctacgatc cgtgatttta attccgctaa atctggcgga gtcaaaaaga
    36121 tgaatacacc atcgggcact ttttctttga cttgttttgc tccttggact tcaatctcca
    36181 agaaaacatc ttttccttca tccaatgtct tgttgacata tgacaaagga gttccataat
    36241 aattcccgac atattctgcg tattccagca tctctccagc ttcgatcatt gattcaaact
    36301 cttctttgct tcggaagaaa taatcaacgc cttcgacctc cccttcacgc attttacggg
    36361 tagtcattga gatcgaatac tgaaaatcat tatcctcact ctcaaaaatt gcttttcgta
    36421 ctgtgccttt tcctacaccg gatggaccag acaacacgat taataatcca cgctctgaca
    36481 tgacgacgtc ctttcaacta gtctttttgt acttatcgtt tattttgcac tttttttctg
    36541 caactttcaa ggttatcttt aattatagct agaaattggt aaaaaagcta ccctgtacca
    36601 agaggtcgta aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca taaacagctt
    36661 ctcatgtttt tcgtttggtt ggggttatta tcgcagatgc aagcttttga acgccgtgta
    36721 taagaggtcg tgaagaagcc gattagtttc gagtatgaag aaaaattttg tgaaaatagt
    36781 ttctcacatt tttgcataaa tttggcttaa taccgagaaa atggtttttg aacatcactt
    36841 attcaaaata aaaaaagatt gtgacacgaa ttttgtcaca acctttaaat gtattcctag
    36901 agcaaagaag ctaagcgaag aaatccaatt ctgattattt attgtatttc tttgttcagc
    36961 atccttgcta aaagcccata ttggacaaag tattcactac acccatgatc tcatcttttc
    37021 gagaacgtgc tttttctgtc ggatcttcta cctcttctgt gtcaattcga acaataaatt
    37081 tccgattcat cgtcacgtaa gcaccgtcgt tgatcaaaat aaacagttcg ttctcattat
    37141 agtctgcaca ggcatctttc catacgtcaa agccgttttt ttcagaaggg atatcccgtt
    37201 taaccacagt ttttccactt aattcgtgga acgttacgtc ataatatttc attatctcta
    37261 cctctttcgt cattcaatat tttgtacttg ttctctgatt ttttctaaga tcgtcttaga
    37321 ctggacgact tgatttttaa tttcgattgc atttgatttg gaaccgatcg tgttgatttc
    37381 ccgattcatt tcttggatca ggaaatctaa ttcccgacct acaggacatt gtgcttcgat
    37441 aagttcatct agtttttgta catggatcgc cagacgatcc agttcctcgt gaatatctcc
    37501 gcgttccaac aagatggcta gctccgtcaa caaccgttgc tcatcgactt tcgctccaag
    37561 aaattcctcc agcttttttt gataccttat ttgaaattcc ttttcataga tttctacaaa
    37621 actatcgagt ttttttagta cttctttgaa ttcttcagta ttctttttca acactaaagc
    37681 taaagcttga ccttcttttt ctcgactcgc ctcaatagaa tcaagtgcgc ttttcaatgt
    37741 atctagagct aactgtgcca attcttccat gctctcttcc ggtttttctt ctaccgttac
    37801 gaagttttcg tccagcgcga agcgttccgc catccgacta attgacactt gattttgact
    37861 accgtatcgt tgttgaattc cgtctgtcaa ttgagtgata agtgaatcaa tcaattccca
    37921 gttgatgacg atctgttttt cgtttttgcc aatataagct agattcacaa atacttcgat
    37981 tcgaccgcgg cttaactgct gtttaataag ctgacgaaaa tcgttttcaa caaagttcag
    38041 gattttagga cttcgtattt gaacatctag aaaacgctgg ttgacacttt ttatttcaat
    38101 atctaactga tacgcttttg tttcgcggat ggctttgcca aaaccagtca tacttttcat
    38161 tcgacagggt ccttcctcat tacatatttt ctattgcttt ttgcagttgt tcaaactctt
    38221 cgttcgtcaa tgtcaggcct ttccccattt tttcatggtc tggcgcccaa tctcgaagat
    38281 cgaattttgg cgggcgacca ttccagctga ctaggttcag ttctttacgc caccccttgt
    38341 tgttttctga caatatagcg atttcttcta cgatttcata tgaaaattct tgtgccatgg
    38401 ttgttcctcc ttgagataat ataaatatag gatcagtaat gtgtcaactg gttgcttaag
    38461 caattcatgc tgcaaacgat ccttgcgttt tccttgtagc agataatcaa aataaacagt
    38521 tttcgtgcgc tcattttgta ttttttgctg gtattttcga taccttcgcc attcttcagt
    38581 acttaattga ccaatttgtg ccaataaatc atccggcata ctttttatat cttgttggca
    38641 gatcatttga atcatcatgt ctacttgata gatttcattg ggcagtaaaa aatgtttttt
    38701 tgctaaaagt tctagcatcg ccaatccgca tgtctctggt acgaccctgt tcttatataa
    38761 attacgcagt ttttgccaaa attttatgct tttgaaaaaa gataattcta actgaatttc
    38821 ttttgttaag taagacaaaa atcctcgcca gtatgttctt gcaggtttaa cagaatgaaa
    38881 tgtataccag ttcccatagt aatagcctaa tcgttttttc atttccagat agcctaattg
    38941 taaatttaat tggttccttt ggctatcaaa aagcagaaag ctgcctagtg tccacaatgt
    39001 ttgacatttc caatggataa aaatgtctgg catacgaatt tttttcgctg ggcctggccc
    39061 ttgcacatct acgacaaatg cctctgttgc tcctttgtta atcgcaatat caataggtat
    39121 tttgttgcga tacccaccgt ctgcatattt attttttccg atctttcgat aagccatagc
    39181 gggataaaat gaagcagagg cgagtatcca atctggtatt tcttctgttt ttgtctgttg
    39241 gatatcagtc actacttccg ctagttctgg cagtttagta gacaccgtat ataaacgtat
    39301 tttgggatta tgtttgagta aggacaaatc caaattgtct ttgaccatct tttccaatgg
    39361 agcagaagaa accccgcctt caattagtgc tgttttcgtc atttggcgtc tttctcgata
    39421 gaagcgttca cgaaggtctt caactgcagc catttctggt aacgcaagca cttgtcttgt
    39481 cgacagcttt ttccataaat tcacagcttt tttcatatct ccttgtaaaa tcaatgcgcc
    39541 gttcaacgca cctaccgagg tacctgtgat aatctcaaag ttgatatcat gttccttcag
    39601 cgcctgccac acaccaatct gataagcacc gtgcgctcct cctccaccta aaacaagtgc
    39661 tgtatgatag accagctttt tatttaattg tgtggttcct tgatagccgt ttttatgaaa
    39721 aatacgcaac cattcttctg atagaggaga ttgaaataaa aaacaacagt tttctttaat
    39781 aaaaaaacga gcgcaagctt ccatataccg aaaaaatttt ttccattcaa aagtttcacc
    39841 ttcaatcaac agattattaa aaataacatc tcctctactt ttagcaatag taaaatagac
    39901 ggtatatttt ttcgatactg ctttaaaagc acattgcttt tttgcagaac gccaaaaagc
    39961 gtctctactt tcttgatgac tttgaaaaaa tggaaggggt tgttttgctt gctggatagg
    40021 cgaatacagc gacattttct gtgaaaagta aacttttttt atctccatcg cgctctcctt
    40081 tttcttcaag tataccagta cgtcataaaa aggtcatgag tctcgtattc gactttgtag
    40141 attccataag aaaacaattc ataaaacctc ctttaaataa aaaaatacaa aaatcacaaa
    40201 aattaattga aaatgagagt gtttttaatg aaaacgtgat tttgtaatgg aattttaaaa
    40261 taaaagaaac aagctttttt aatgcaaatg ttgtaaaata aaagagatta agaggaaata
    40321 agaggaggaa catgatgact gagtcagttt atgtacatat tgataccaca agtaatgctg
    40381 ttttaacaaa agggctgact gctactgact ttgcaaacag tatcgtgcat tttcctcaaa
    40441 acttgctctt gcttgatcca tctgcttctg ctggagaata tgaatcccat acagggctga
    40501 aagtaatccg tggtacagaa aatattcagc gtttcttttc ctcttctcgt aacaggcgtg
    40561 gattcgatga attgaagtgg atcgacttta ctgatttaac gatgctgaaa gaattgacac
    40621 ctttagaaat ttcagaatta ttatattttg gtcatatgaa aacacatctt cattcgccgt
    40681 ttttttataa actacagaat aattttgtat acttcgatct taatgatcag ctgaatcgga
    40741 tttattatcg ctatttagat gaattttata ggatttttgc tagtaaatta agttcgatct
    40801 tgtcagataa gatcaatgta aaaaaatctt ttttcaaaaa agaaacacct gttgaaaaaa
    40861 tcagtgtgga attattgaaa gaaatgcgta atttgatgca ggaagggatc attttttctt
    40921 ttgatcaagt tggtttgatc gatggtaaat atcgtatccc aatctatgtg attgaagatt
    40981 atatttggaa attaaaaggc acccggtatc gagaagagga aatcatcgct actttaatct
    41041 actctgtcac cgatcgacac tggcaattgg tagaagatgc cgatctttct tatctgccat
    41101 tgaagtagat ctatttctta tcaaaaaata aaaaggaaac aagaaactag gacatgattc
    41161 tgtctcaagt ttcttgcttc ttttttattt acagctcctg tcgtttatct ggcacaaaaa
    41221 tcgaaggagt cgtttgttgg atccctaata aaacgatgat cgttacaata gctgtactca
    41281 acccgctggc accattcatt acgaaagaaa agagccaagg attcatcccc catagtgcat
    41341 acgctcccca gaaaaccact cctgcaataa aatgccaaaa atatctggaa agtgcgccaa
    41401 tcaatgcacc aaacacgatg ctttttctaa tttgtttcgt attatcgtct acatagcctt
    41461 tttggacatt tgaagccatg agccctgctg cgcctgcaaa agtataggca atcgggtact
    41521 caatcaacac ttgaacgaca cttaaataat aaacttgtcc caacggaaaa tgtaggatgc
    41581 cccaaatgaa acctgccagc atccctgcct ttgtccctct tcttaacgca aaaagagtca
    41641 atggaatctg ccctaatgaa atagaaaaac tgctgccgat ctggatcgga atcaacgaca
    41701 acaccatcgc taacgctgca acaatcgttc cttctaccca aactctattt tttcccataa
    41761 aaaaacttcc tcctttgaat aaaaaagtca caaaggagga agcagctttc gaaaatagtc
    41821 aaacagctgt ttattcacaa ttcctacgct cgcataaccg atacaggtac gaagggttta
    41881 gaaatagatt caatctcagc ccaattggac tcccctttgt gagtttattt attatttatt
    41941 ttttgtttca aacaatggac taactggttt gttttcatgg atacgtttga ttgcatctcc
    42001 cattagtccg ccaatactta cttcatcgat tttgtcgatt ttacgatctt ctggaagata
    42061 gatcgagtct gtaacaacta gacgctcgat agctgaatct tctattcttt gtaaagcagg
    42121 gccggataat actggatgtg tacatgaagc atacacacta gttgcaccag cttctttcaa
    42181 agcattggca gccaatgtga tcgtacctgc tgtatcgatc atatcatcga tcagtacaca
    42241 agttttgcct ttgacttgtc caatgatatt cattacttct gcaacatttg cttttggacg
    42301 gcgtttgtct atgatcgcaa tcggagattt caaaaattcc gctaatttac gtgcccgtgt
    42361 gacaccacca tggtctggtg aaacaacgac aacatcatcg cctttgattc ctttttctaa
    42421 gaaataattg gcaataagtg gcgcacccat caaatgatcg actggaatat caaagaaacc
    42481 ttggatttgg actgcatgaa ggtccaaagt cagcattctt gttgcaccag ctttttgaat
    42541 catgtttgct actaatttcg ctgtgattgg ttcccgtgca cgtgctttac ggtcttgacg
    42601 cgcatagcca taataaggca tgactacgtt gattgttttt gcacttgctc gtttcagtgc
    42661 gtcaatcatg atcagcaact ccatcaagtt atcattgact gggctgctcg ttgattgaat
    42721 aacatagaca tgcgatccac gaatactttc ttcaatgttt acttgaattt ctccatcact
    42781 aaattgagta acagatgatt ttcctaactc gacgccgact gctgctgcaa ttttctctgc
    42841 taatgggcga ttggaattta acgcaaaaat ttttaatctt gggtcaaagt aatgttttga
    42901 catggggacc tccactttct ttttcacaac tctagaattc tacctaataa atagtagtca
    42961 tattttttaa ataaatcaag tgattttgca aaagtcttag tttagataag ggagtttttt
    43021 tgcatatcct tctttattga cttgtcttgc tctcgcaatt gccagcgcat attctggaat
    43081 attgtctgta attgttgacc cggcagcaat cgaactgttt ttagctacct cgacaggtcc
    43141 gatgatattc gtgctagaac caataaagct gtggtcgccg acagtcgtat gatgtttgtt
    43201 ctttccatca tagttgacga agacaacacc acatccgaca ttgatttctt ctcccagcgt
    43261 agcatcacca acataagtca agtgaccgac tttagttcct ttgccgattt gagcattttt
    43321 cacttccaca aagtttccga tatggacgtt ttcgccaatt tcagcttttg gtcgtaaatg
    43381 tgcataaggt cccacatctg catgtttctt gacatggctg ctttcaatga ctgagttttc
    43441 aatgacgacg tgatcctcaa tcctactgtc tacgattttt gaatgtgacc cgatgacaca
    43501 atcagaacca atgactgtat ttccttggat ttgtacacct gcttcgatca atgtgtctgg
    43561 accgatttct acgcctgcat cgatgtatgt cgttgctgaa tcgacaaagc ttacgccatt
    43621 gaccatatgc atctggttaa ttcgctttct catgatctca tttgctttag ctaacgcgat
    43681 ccgatcattg actcccattg attcttcaaa atcatccgtt tgataagcag caactgtatg
    43741 gccttcttct tttaagattt cgatgatatc tgttagatag tattcacctt gagcattgtt
    43801 tgttccaact ttgcttaacg catcgaacaa agcttcgttg tcaaaacagt aagttcctgt
    43861 attgatttct tgtacaagag cttcttctgg tgttgcatct ttttgttcca cgattttttc
    43921 tacgatccca atatggtcac ggatgattcg tccatatcct gttgggtttt ctgcttgtgc
    43981 cgtcaagatc gttgcacttg cattttttcc ttggtgatat tcaaaaagat tgttcagcgt
    44041 ttcagtagtc aataatggtg tatcgccact gataactaac gttgttcctt tttttccttc
    44101 caagaaagaa gcagcttgca aaacagcatg tcctgttccc aattgttctg cttgtaacgc
    44161 atatttactg cgttctccta gttgtgcttt aacttgttct gctccgtgtc caacgatcgt
    44221 aatcacttca tctggtttcg tttcactgac ccgattaatg atatgttcta ccataggttt
    44281 accagaaacg ggatgtaaaa ctttatataa ttttgacttc atgcgggtac ctttccctgc
    44341 cgccaaaata attgcataac gtgcgtccaa ctgcgtcact cctaaatata gtttgctgat
    44401 ttcagtttat cccagtatac ccattttttc aacaaaacaa gtgattttct tttatcccag
    44461 cgttttctgg ataaaaaaat agatagacca taacgggcct atctatttgg taaccggtgc
    44521 tctcctgcca actcctcggt cacaagtcac actactcata aaacatgaaa agctgttttt
    44581 tgaaatcgtt tcttgtgact tagagttaaa cggtaggctt acaacctctt cattaaacgt
    44641 ttttcaatca gctgaccttc ggtattagct caataaacgg caaaatatga ggagcaattt
    44701 ttccgtttat tgagctaata ctcaggacag gacgctgatt tcacaacctc tagataaacg
    44761 gtgttcaaaa gccagtttct cggtattaag ccaaatttat gaaaaaatgt ggaaagccat
    44821 tttcacaaaa tttttcttac tactcgaaac taagcggctt tttcacaacc tcttattctg
    44881 aaaaataatt tcctggcaca accgtaatat ttttcgtttg agtatctaca tctttgacat
    44941 aaagcagtga cgtataatca tcgatggcgc gatgaccgtt gaattttgat tcggcaaata
    45001 cagtgatgcc aacaagttct gattcgaatt cttcaatcaa gctcttcatt ccgttgactg
    45061 ttccgccgcc tttcgtgaaa tcatccacta caaggacacg tgaaccacgt ttcaaacttc
    45121 tcttagacag ttccatcttt tcaattcttt cagaagatcc agacacatag ttgacactta
    45181 ctgttgatcc ttctgttatt tttgagtccc ggcgtacaat aacgaatggc gcattcagat
    45241 aataggacac agcttgggca ataggtacgc cttttgtggc tacagtcatt acagcatcga
    45301 ttttttcacc aaggtattta gaagcaatga ttcttccaac ttgacgcagc agttcaggtt
    45361 ctcctaacaa atcagagaga taaacatatc ctcctggaag cagacggtct tgttctgata
    45421 gacgttctgc tagagattca atatattttt tcgcctcttc atatgaaatt tcagggatga
    45481 acaatacacc acctgcagca cccgggattg tttccaaggt tccataccct cgttctttaa
    45541 atgttttctt gatgattccc aaatcttcac tgatagaaga tttagcagat tcataacgtt
    45601 cggcaaagct tgttaaggaa atcaattcat gcgggtgatt caataaatac tgtgtcatgt
    45661 caactagacg ttcactgcga cgtactttca cctattccaa ctccttttaa gaaattttat
    45721 cgttttacat tatataagtt tttcttcaaa aattcgagca ttttatgaaa aaataagaaa
    45781 atagttcggt atttattaaa ataaaaagaa gcctataaaa aatttttcgt ttttataagg
    45841 cttcttttct ttataattta gttatttttt cttctgaagg caaccaatat tcgtttgatg
    45901 atatttacaa tcaggaacaa agcaataaag actaatgtga ttgttgctcc tggaggtgta
    45961 tctagataaa acgagctagt tagtcctgac agcatcccta gaaatcctac acaaacactg
    46021 atagcaatca cgacattgaa gcttttgcct aatcgcatac cgattgctgc gggaagaacc
    46081 atgattgcgg atatcaaaag tgcaccggca atcgggatca tcacagcaat agccacacca
    46141 gtaatcacat tgaacatcat cgacatcaaa tgaacgggta gcccatccac gtgggcggta
    46201 tcttcatcaa aagtcagaac atacatcggc cgtttgaata aaaagaacaa tataccgatg
    46261 gcaacgaata agattcctaa aaagatgact tgctcccatg taatggtcac gatcgaacca
    46321 aacagatagg attggatact tgttgctgaa ttccctccgc tcaaattcat caatactaac
    46381 gctagcgcca aaccaccagc cattaaaatg gcaatggaga tttctgaata ggttcggtag
    46441 atcgttcgca gatactccaa tatcacagct gctaatacaa cgactagcat ggtcgtaagt
    46501 gtaggattaa ggttcaaaaa gaatcctaac gctacccctg ctaaagagac atgagaaagc
    46561 gtatcagcca tcagcgattg tcttctgatc actaaaaaca cacctagcat cggggcgatt
    46621 ccggcaatga agatagcggc aagaaacgct cttctcatga attcatatga aagcaacgcc
    46681 attgagaatc ctcctttctc accagtcgga tctgtctgtc cgcatactgt ttgatatctt
    46741 catgatcatg ggtgatcatt agaactgatt tcccatggac atgcgcacta tgtcggagaa
    46801 gacgataaaa ttcatttctg gattcttcat ccatacctgt tgttggttca tcaagaacaa
    46861 ataagtcagg gtcagtagca aaaatacgcg ctaaactgat tcgctgcttt tgtccgccag
    46921 acaattcacc tattcgccga tttcgcatat cccacatccc tacagcttct aaagcacgct
    46981 gtacatgttg atgatctttt tcagagagac gcttgaacca gcggcctctt ggatatcttc
    47041 ctgaacggac taattcgatc accgtactag gaaaacctgc attgaaagat gcaacttgtt
    47101 gaggaatata accgatactt aatttttttc cttcttgatt tttctcagca atctttatca
    47161 ttccttttga aggtttcagt aatcctaacg atgctttcac caaggttgac ttggctgctc
    47221 cattttctcc agttaaaatg acaaattcac ccgcatctac atgataagag acatcttcta
    47281 gtacaggttc atcatcatag taaaaggtca aatcagatat ttcgatataa cgcaccttac
    47341 aacctccatt ctaaaactta attgatactt tcttttaaag ctttcagatt tttttccatg
    47401 acagaaatat aattttcgcc tgctttgatt tgttcattag tcaagctttc taaaggattc
    47461 aacacttcta gcttcactcc tgtttcattc gacaatgtct cagctacctt cgaagaggca
    47521 ttttcttcaa aataaatcac tttgatgttg tttttcttca caaattcttt tagctcagct
    47581 aagcgacttg gtgtgggttc ctgatctggt gaaacgcccg aaatcgctac ttgttttaag
    47641 tcgtattgat tcgctaaata agcaaaagca gcatgctgag tgacaaatgt gcggtttgtt
    47701 gcatctttta gctcatcgga gtatttttga tccagtgctt caagcttttt gatataagca
    47761 tcggcattct tcgtaaaagt ttccttttta tctggatatt tttcgcctaa ttcttcagca
    47821 atcgttctga cttcttttat agctaatacc ggatcgagcc aaacatgtgg atcgtattca
    47881 tgtgaatgac catgcccttc ttctgattct tcatgttcgt ctgcttcttg cgattctaaa
    47941 cggtcgattc ctttagctgc ttcgatcatc aaggtctgtt tgctatccac tgaatccttt
    48001 aacgaatcca caaaaaattc catgtctgaa ctattataca cgaaaacatc tgcatcggaa
    48061 atttctgctc tttcttttgc acttggttcg aaatcatgcg gctccgttcc agcagggatc
    48121 aaaagtttca cgtttccttc atcccctacg atctcttttg taaaatcata catcggataa
    48181 aaagtcgtaa cgatcgtcaa atcctctttt ttgtctgctt ccttgttcgt atttccacat
    48241 gctgcaaaca gtaaagcacc tatcattacc gtagctgtca aaagatattt tttcatttat
    48301 atgctccttt caatgaacaa atcggaattt tacgatttat taacgtgaac taatgtatca
    48361 aaataaaaaa acacagtcaa tagaaatcca tcaatttctg atttaagcat gtatattctt
    48421 gattaaatcg taaaatggat gagttgctgc tcatatctag ccatttcact acaataaaaa
    48481 actgaagaat accattttag gattcctcag tttttcatca cctattttac ttcttatatt
    48541 ttattgcagg gttcgtacta aataaacttc ctcacaaaaa ccttttaacc cattatatac
    48601 tctctgcgct cttgaataat gttgacacaa ggcaaaaacg gttggtccgc ttccactcat
    48661 caatgcagca tctgctccgt acttgatcat acgctctttg atttgatgga tgactggatg
    48721 ccgctttccc gttatatctt ctaaactgtt tcccattttt ttgatcatct gctgataatc
    48781 ttgctctcgg atggcttcag caagtccgtg gatgtcttga tgttggatgg cttgcgtatc
    48841 tacttctcta aacactgtac gtgtagagac actcattctt ggtttgacca acacaaccca
    48901 gcactgtggc atagaaggta atacttggat ttcttcccct ttgccaccga caaatgccgt
    48961 acttccgtag acacagtaag gaacatctgt accgacttcc aaaccgattt ctgccagttc
    49021 ttctaacgaa cagcccagat tccataattg gttgatccct cttagagcag ctgcacagtc
    49081 tgtacttcct ccgcctaatc cagctgctac tggaatattc ttcttaacaa agatcttgac
    49141 accggttttg atattgtatt tattttttag caataaagca gcttgataaa cattgttccg
    49201 ttcatctacc ggtaaaaatg ctttatttgt ttctacaatg attttgtctt ctgttatttc
    49261 ttcaaaaaat agatgatctg ccaagtctac gctcgacatc accatttcca actcatgata
    49321 cccatcttgc cgtctatata atacatccag tcctaaattt atcttggctg gcgctttttc
    49381 aatcaattcc atcctctcac ccattcgaaa agtctaagtc gcaagtattc tatcataggg
    49441 aaaaataaaa gtatagctta tgtctgccta gtggttgatt ttgtcatcgt ttcaacagct
    49501 ttcacagaat tttctcttca taatccaaac aagttctagt gattcttata attctgtgag
    49561 cacttcttct gccaaactcg gaacatttcc tttttctttt cctatcagac tgagtagctg
    49621 catggtagca aatccgaaat tacttccttt cctataagca aaataacgtc cttcccaatg
    49681 atcgacatat tttaatttct tttcataagc agactggaag gaatagaaaa aattaccata
    49741 attatatacg atatgcatga ctttttcttg aaagaaagaa aaatctgttt ctccaacatt
    49801 agctaatgga gctaagccta gattggcttc cgagtagccc attttctcgt atacaataaa
    49861 cagattggct aacagatagt cagctaattc ctcagattct ttaggtaaga cccgcaacaa
    49921 atcatatccc gcctgcttct tcgtcatcgg ctgagcggtg atgaagccaa cgactttttg
    49981 atctttacgg acaataccga caccgctaga taatacatat gatttatcaa atcgtcccac
    50041 agagaagtat ttttctcgtg caccttgaag ccatttttgt gaaacttcat ttacagcttg
    50101 atgtaattct tccggcagtt gatcgtacca agtaaaatgg tatccttctt tcatcaaacg
    50161 ttgatattca agttgctgac tcagccgaga caagtcttct gttgctagat caacaatccc
    50221 tgcttcacct actttcgtga agtgaaaacc caattcatga agcatcacta cgtagctttc
    50281 tgatatctta taaaacgcaa gctgatagcc taaacaatct gcttgtttca taaactgatt
    50341 cgttgctgcc cgcatcattt taggattgcc aactggatct cctaaaacaa agcatttgtt
    50401 tcctttgatc tgataaccaa aaacgacttg atcttggtcg tcttcttggt aataaaaata
    50461 actgtaacct gacaagcgaa gctgatggct tgtagctgtg cctccgtatg tttccaataa
    50521 acggtcaaaa cggtcttttt cgtactcact gccaagcttc gtagtatctt cagctaaata
    50581 ttgataaagc gccactaaag ctagcaatga gatgcccaaa ccaataagcc ctgagaacca
    50641 cacatcatct gaaggaaaca aaataaaatg atttcctgtt attcgaccga ctaaaaagcg
    50701 tccgctgtga tagcctgcaa ttgcgtaaac gataaacaaa aagccgaaca agctagcatc
    50761 aaagattata gctccccaag aataaacgaa ttttgttcga taaaattctt ttctggataa
    50821 ccacacagct aacagaatca agacatatac caatatcaac tgccaagata acgtacgtgt
    50881 gattgtattt aaaataccaa aagatagtaa agcaatcgta ggcagaaatg cctttttgac
    50941 ttttactgaa agtgctctag caaggccgag taataaaaag ccaaccaata gattcactgt
    51001 ctgatctaaa aaattgaatg agaacggcaa taatacttga aatagccgac tgattgcaga
    51061 cagattagtg attgttgata gaagtaccat catgatcccc gcaaaataga cagcacttac
    51121 gagcacgata tgcgcaacct tttggaaaaa cagtcgcgga atgttatcta aaaatcgatt
    51181 gattttgact cctgtatgtg tgatgaacaa tagaagtccc gtcataaaag gtagaacata
    51241 ataaaacaac cgataatata atagccaaac tactgctaca tcttgccgaa cagacaattg
    51301 actcattcct aagatcatca aaacgtcaaa agtccccatt ccacctggga ccatcgtcag
    51361 cattcctatc aatgtagcaa tcatgaacat aggatagatc gaaagcatcg aaatatctat
    51421 tctcatcaac ttgccgatga tcaaaaatac cgcaagggct cccgtccatt gtccaaagga
    51481 tgccagtagc agaccaagca agccttttgg ataaaactcg aagaacaatg tctttctctt
    51541 tagataagca aaaaagaaaa tgactggtgc taaaaaacta ccgccgaaaa gccagatcca
    51601 atagcttcga aaaatacttt ctgactgaat aaaaaagaca tcaataaatg taagaaacga
    51661 ccatacagac aaaccagtca gcataaatag tgcgactttt gatacagtgg ctaaaaccat
    51721 ttttctattt gtctgctttc cataaaaact agcccgcaga cttgctccta ccacaccacc
    51781 aaaaccggcg agattgttga tcgtgtttgt tacccacgca gcaagaagaa actcttttct
    51841 ttccattttt ggttttcctt gtttttctaa gactctgatc gtcacccaat catacaacaa
    51901 catcggagtg acacccagca gtccagccag aatcatgagc aggatcgtca tgcggctttg
    51961 ttgtcccatc ctttgccaaa tatcttgcca actcatgcca ttagcaatat ttgcgacttg
    52021 atttgccaca aagactaaca cggagccgaa aaaaatcagt tttaaaatca gactatgttc
    52081 ctttatccat tgcagcatca agtatcgttt atttttcaca ttttcccatt cctaacttgt
    52141 atacttttgt gtcatacccc aatgttatct tatttatttt aatttttcca ctttagacct
    52201 gttctttgct tgcgatgata gaaaaagaaa gatatcctaa tgctaaagga gaggataaca
    52261 tgaaagtagg atttatcggc acagggaata tggcacaagc tattattgat ggtttattaa
    52321 aaaaaggaac agtctcgaaa gaagaggtgt tcgtttccag tggacatttt gaaaatgcac
    52381 aaaaatttgc tgctgaaact ggcgtccatg catgcaaaag taatcaggaa gttgcatcac
    52441 aatcagatat cgttctttta gccgtgaaac caaaaatcat tgaaaaagta ttggaagaac
    52501 taagagaata tagccagaaa gtcttattca tttctattgc ttcaggaaaa tcattaatag
    52561 atttagaaac agcgcttgaa gatcctcagg cctccatcgt acgtgtgatg ccgaatgtca
    52621 atgtcagcgt aggagcaggc gtttctgcga tttgcaaaaa tgaagctgcc acggaggaac
    52681 agcttcagca agctacgatg atttttgaag caatcggcag cgtctatcct ttagcagaat
    52741 cagatttcag tacattcatt ggccttgctg gcagctcacc cgcattcgtt tacatgctga
    52801 tcgatgcgat gggacggact ggtgtactga atggtttgtc caaacagaca gccactgaga
    52861 ttgctgcaaa agcaattatg ggttcttgtc aaaaattcct ttcaagtgat aaaaatccat
    52921 gggaacttgt agaccaagtt tcttctcctg gcggtacaac tgttgcaggt gtagttgcct
    52981 tagaagaagc aggattcatc ccagcaatca tcaaaggaat caatacgacg atcgagaaag
    53041 atcttgagat gttgaataaa aaataatgat agcaatgttt tttcgtgcct tacaaaaaaa
    53101 gaagagctgt ggcttttgcc gcggctcttc ttttgtattt tttattattt agcataatca
    53161 gttgcacgag tttcccgaat aacgattact ttgatgtgtc caggataatc cagttcttct
    53221 tcgattcgtt tacgaatatc acgtactaaa cgaacagcgt ctaaatccga gatttcttct
    53281 ggcttgacca ttacccgaac ttcgcgtcca gcttgaactg cgtaacttga ttctacaccg
    53341 gcgaagctgt tcgaaatatt ttccagactt cttaaacgac ggatgtagtt ttctaatgat
    53401 tcacttcgcg caccaggtct tgctgctgag agcgcatctg ctgcagctac aaggacagag
    53461 ataacagaag tagcttccac atctccatga tgagaagcga tcgcgttgat tactactggg
    53521 ttttctttgt acttggcagc taattccgca ccgatctcaa cgtgagatcc ttcaatctca
    53581 tggtcaagtg ctttcccaat atcatggagc aacccggcac gttttgctaa ttggatatct
    53641 tcgccaagct ctgctgctaa gataccagct aattttgcaa cctcgaccga atgcttcaag
    53701 acgttttgtc cataactagt tctgaatcgc agacgtccga tgatcttgat tagatctgga
    53761 tgaagtgtat gagcaccgac ttcaaacgct gcctcttccc cgtattcgcg aatacgttca
    53821 tccatttctt tacgagattt ctcgaccatt tcttcgatac gcgctggatg gattcgtcca
    53881 tcttgtatca gtttttccaa ggtcatccgt gcgatttctc ttcggattgg atcgaatccg
    53941 gaaagaacaa ctgcttccgg tgtatcatcg atgattaaat cgataccagt cagcgtctca
    54001 agcgttcgaa tattacgacc ttctcgtcca atgatacgac ctttcatttc atcattcgga
    54061 agggtaacga ctgaaacagt cgtttctgaa acttgatctg ctgcgcagcg ttgaatcgct
    54121 aatgataata agtttttcgc tttgcgatct gcttcttctt tggcacgctg ttcagattct
    54181 tttaccatta gagttaactc atgattcagc tcttcttcag tcgatttcat gatgacatct
    54241 cgtgcgtcct cttttgataa accagcaatt ttttctagtt ctttttgttg atcttcaatc
    54301 attttttcaa cgtctttttc tcgctcttca attaattgct gttttgaact aagtgcttct
    54361 tctttacttt caagtgagtt ctcgcgtttt tctaacgagt catctttacg attcagcgtt
    54421 tgttcgcgtt gaatcaaacg attctcttga gattttaatt ctaacttact ttctctcagc
    54481 tcactttcaa cttcagaacg gtatttctga ttttcttcct tagcttctaa caatgcttct
    54541 ttttttagag tttctgcttc tttttttgca ctatcgatga ttccagcagc tgatgattgt
    54601 gcaccagcta tttctttctc gtgacgtgac tttgcgacca taaaccctaa accaagaccg
    54661 acaattaaac cgatgatagc gaggagaatg ttgaatacca taaaatccac ctccatacta
    54721 tctttttcat ttttatcatc tatacagctt ctatgataaa ttattctaaa ctcgtcaata
    54781 tgcatcttcg catatatgtg tacaaaaaac atgcacaact ttattctaat gtttgtaccc
    54841 cgtagtgtca actttaaata aacaaagaaa cggctttcta cttattcatt aaacgatggt
    54901 ttttaaaata aatgacacta gtttcatata ggtaaacctt taaattgaga aacttttcta
    54961 ttaaattatt ctttgtagat gaacagatat ttttatttta tgtacccact cgtataatta
    55021 aataactcac gatttcttta ttcaataaaa aaacggcagg tcaaggagag tacctactct
    55081 tcagaccagc cgtttttgtt tatcataatt tttattcttc tactaaaggc aattcttctt
    55141 gtcctttttc atcttctggg acagcgactt cttcaccaat accataagct gctctaacta
    55201 gagcagaaac ttctgccatc atttcaggat gattagccat atagatttta gcgttttccc
    55261 gtccttgacc aatccgatct tctttataag aataccaagc accgctttta tcaacaatgt
    55321 ctttttctac tgccatgtct agaagttctc cttcttgtga gatccctaaa ccatacatga
    55381 catctacttc agcgattttg aaaggaggtg ctactttgtt ttttacgact ttgatctttg
    55441 tacggttacc aacaatatct gtaccttgtt tcaattgttc tgcacgacgt acttccaaac
    55501 ggatcgttgc gtagaatttc aatgcgcgtc ctccaggagt gatttctgga ttcccaaaca
    55561 tcacgcctac tttttcacgg atttggttga tgaaaatagc gattgttttt gttttgttga
    55621 tcgaaccaga gagtttacgc aatgcttgag acatcaaacg tgcttgtaac ccgacatgtg
    55681 agtcacccat ttcgccgtcg atttctgctc gtggaactaa agcagcaact gaatcgacta
    55741 ctacgatatc tacagcccca cttgatacta aagcatcagc gatctctaga ccttgttctc
    55801 ctgtgtcagg ctgtgaaaga agtagttcat cgatattcac acctaatttt tgtgcatatt
    55861 gcggatctaa cgcatgctca gcatcaatga aagcggccgt tccgccattt ttttgtactt
    55921 ctgcaatagc gtgtagtgca actgttgttt tacctgaact ttcaggtcca tatacttcga
    55981 tgatacgtcc acgggggtaa ccgccgacac ctaaagcgac atctaacgca agagagccac
    56041 ttggaattgt agagatttgt tggtcgattt tttcgcccaa tttcataata gagcctttac
    56101 catagctctt ttcaattttt ttcagtgcag catctaaggc tgctttacga tcatctgcca
    56161 atacgataat cctccttata tttacaaatc agagcaacat ttcattatcc ttatcatatc
    56221 ttttttagtg aaaaaaagca agaaaaaacc gaacaaatat tcgcatttat cattttctta
    56281 aaagctgttt tctcaaaaga tcaaatcctt gcataaccgc attatatctg atagcagcac
    56341 gatctctggc aaagtgatat ttttccgaaa ccacgccgtc tttagatgaa atagcgatcc
    56401 atactgttcc tgcagattga ccttctaacg tgtccggtcc agccactccg gtgaaagcta
    56461 cactgtaatc tgttcttgct atctcacgtg cttgaatggc catctgctcc acacattctt
    56521 tgctgactgt tccatattct gctaatagct ccggatcaat ctccagaaaa ccagcttttg
    56581 tttggagcga gtaggtaacg aatccgcctg gaaatacttc agatacacca gcaatgtcgc
    56641 ctaatgcggc ttggaaggcg ccggctgtca aactttccgc tgctgttaca gtctgcttgt
    56701 tttctttcag tagttccact acgacttttg ctagcgaatt atcatcgccg tatccataaa
    56761 aatattcccc tactcgttct tggatttttt cttctaatgc taaaagagct tgattccctg
    56821 cctgaacatc atttgttttc actgtcagtc gtaatgtcac ttcatttggt ttggcatatg
    56881 gtgcgatcgt tggattgatc tgtgtctcaa tcagatcttt tagctcagtg accagtcgcg
    56941 attcaccaat cccataaaag cgcaaaactt tagaaattag tttttcttca gaaggaaaac
    57001 gttcctctag taaaggacgt acttgttcca caaacattgg tttcaactca ttaggcggac
    57061 cgggaagaag gatatacgca tgtgtatctg tttgataaaa agtccctaaa gcaagccctg
    57121 tacgatttgg tagaggaacc ccgccttcga taatctggga ctgttgcaga ttgtttttgg
    57181 tcatttttcg atgggttgtt tcaaaatatg ccaataattt tttgtatcct tccgtatttt
    57241 gtatgagaga cttaccgagg tgagccgcag ttgcttcttt tgtcaggtca tcttctgtcg
    57301 gtcctaatcc gccacataag agtatgagtt cacttcttgt ttcagctaga gcaatcaact
    57361 cttctaaacg ctgctgatta tctcctacaa ctgtttgata ataaacttcg atacctagat
    57421 cagctagctg ttctgacaag aaagtggcat tcgtattcac gacttgtcct agtaaaagtt
    57481 ctgttccgac agctattatt tctgctttca ttacttcccg ctcccttata tagtatacgc
    57541 tgtattttta tattttttta tttaaaaaga gggcaaggag ctgtgacaaa aatcttgtca
    57601 cagctccttg ttccaaataa acagtgttct cctgccaaaa cctcggtcat aagtcacaat
    57661 atacataaaa catgaaaagc tgttttttga aattatccct tgtgactcag agttagacgg
    57721 caggctcaca acctctccac taaacgatac ttacattgat cctttgaaca caccgctgtt
    57781 tttgatgaag taatccacac ctgaatagat agtaaagatc agacaagcat aaagcatgat
    57841 ttgatctact ggaataccga tcaggctgaa tgggatatta ttgataaaca gcaagataat
    57901 agcaaccatt tgtgtagccg tcttgacttt tcccggccaa gctgcagcca tgacttctcc
    57961 atgttcgaca agtagtaaac gcaagcctgt gacggctaat tcacgacaga caatgatcgc
    58021 tactacccaa ccaggggcct ttccttggtc aaccaacatg ataaaagcag tcataactag
    58081 cattttatct gccaacgggt ccgcaaactt gccaaaatta gtgacaaggc ctcgcgcacg
    58141 ggcaattttt ccatctaacc agtctgtgat actagctaaa gcaaaaataa ctgcacctac
    58201 tagctgtgtg acagccagtg tggtgtctcc tacgttaaat tgtccccaat ctaaaggtaa
    58261 acctacaacc aaaatgaaaa tcgggatcat acaaattcta agtacagtta atttatttgg
    58321 taaattcaca ctatcgactc ctttcttccc tattctacgt gactatcagc gaagtttcca
    58381 ccgatattat ttacttttcc aaatgaattt attcaaagga gtatttttat tgaaattgat
    58441 ctttttgaat taacgaagaa ggaccgcgac acagatttgt cacgatcctt cttttttata
    58501 cctacaagta aacagatgcg taaactaatt tatacgatca ttctgcgtat tgaagagtaa
    58561 ggttcacatt ttttggactc tgattgtttt cccctggatt aactggtacg gattctccat
    58621 tcgctttgat cgttgcattg cttgctgcac caatcgtgat ggtcgcattt gttgctgttt
    58681 ccggtaacac ggtactctgt gtttcatttg ctgccagtgt cccttgataa acataggcat
    58741 tgtctactag cacacctaac catacacgat tgacagcagt aaattcaagg gttacaggct
    58801 tggtagcgtc tgtgatattt actgcgatgg cactgccaga atcttctcct gtagctattg
    58861 ccattttctt ttcttcactt gattttgttg ttgattctac tgtagaagac tctttggtct
    58921 gcgtgctttg ctctgaggaa gaggactcct cgactgatcc ttctacttta agcgaagaag
    58981 ctgtgtctcc gattattgga tcagcttgac gatcttgcca agtcatatag cccacgacaa
    59041 cgacaatcgc caaagcaacc aatcctaata aaatgacagg aagacttgtc caaaagcgac
    59101 ttggatgcga ttcttcctga tgcattgctt ttctagaagt acttactgtt tcaggctgcg
    59161 gacgttcagg gaccgatcct gtcaatttgc ttttcccatc aaaaacatcg actaaatggt
    59221 ctccatcttc tcctacagct tcagcgtatt gccgaataaa tgcccgcacg taaaatttac
    59281 caggcaattg gtcaaaatca tcattgtcga ttgcttccaa ataacgtttt tgaatttttg
    59341 taatctgctg taattcatct aaagatattt ttttattcag gcgtgcttgc cgtaattttt
    59401 ctccgatggt ttcaaaagcc actcgttcat cttctccagt ctgtttgatt ctccgaagca
    59461 tctgctgttg caacgaaaga cgttatgttt gggtgctgtg acaaaagtca tgtcacagct
    59521 ccttttttcc gaataaacat tgttctcctg ccaactcctc ggtcacaagt cacaatatcc
    59581 aataaatata agaagctgtt ttttgaactt gttccttgtg actcggagtt aaacggcagg
    59641 ctcacgacct ctttcttaaa cggtgttcaa tcagctgttc ctcggtatta gctcaaaaac
    59701 cggcaaaata taaggagata tttttccgta tgtttctcta atactcaggt caaaacgctg
    59761 atttcacaac ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagtccaa
    59821 ccaagttaaa aacattaaga agctgttttt acttggctgt tcttattact tgatgcaggg
    59881 cagctttttc acaacctctt ggtacacggt gttccagaag tagcttcttc ggcaataagc
    59941 cgaaatatca caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct
    60001 gaccacttct gtcacaacct ctttgattac ttcgtttgat tttattttaa tataagttga
    60061 ttaaaagaga gcatgatttg ttttattttc tcactaattt ttccaacaca actaagaata
    60121 ccataaaagc tgattttgga ggaggttcct actacaagtc taaaacgaaa tttaagactt
    60181 ttcctcataa aatactggtt tattttggtc tcatgtaaaa ctcgctgaag gcctcttcac
    60241 ttataaatgc ttccccagct gccagtacgt ctttcatttg gatcgaatcg atgatttcag
    60301 gaagatcaaa taaagttcga tcgccaaata aactttgcgt aaattgattg gcaatatatt
    60361 cgatcgaatt taatgattgg aaatattgtc caagcatttt cttcttcagc aaatcgagat
    60421 ttgtttctga cacttccgga tcatcagcga atccaagaat gatttctttg actttttctg
    60481 ctgctttctc tggttcgtcc gtatctccgc tgaagtccgc aaagtgaaat tcacgatcca
    60541 agctgaattc aaaaccaaag ctgtcatcga taattccttg attgtacatc gctagatagt
    60601 ttcgagaagt attgcctaaa atcatttgga acaacagatt gattgctgtt ttatagcgta
    60661 acagttctgt tccttcttgc ggcaatgtgt ctaatccttt aataccaagt acaaatttat
    60721 ctcgtgtaat ggctgcttcc aatgcacttt gtttgatgat ttcttttgtg ttttcaggga
    60781 aataacgtac aatttcttgc tttggaggga aattttttgc ttcttggttt tcccgaataa
    60841 gtttcatcaa tttctcaggc tccatcttac caactacaaa taaaaccata ttgcttggct
    60901 gataaaacgt ccgatagcac gtatacaagt cttgagctgt gattttgtcg atactttcaa
    60961 ccgtgcccgc aatatcgata tgcaatgggt gtgtaggata caagttattt agtatgccaa
    61021 aaaacatccg ccagttaggg tcgtcttcat acatttggat ttcctgaccg atgattcctt
    61081 tttccttgtt tacagtttct tctgtgaagt aaggtgcttg tacaaaatcg atcagagtcg
    61141 tcagattctt ttctacctga tccgtcgtag aaaacagata gctggttttc gtaaaacttg
    61201 tgaaagcatt ggcggaagct ccttgtttcc caaataattg aaagacatca ccatcttctt
    61261 tttcaaacaa cttatgttct aaaaaatggg caattccatc tggaactttc accttttctt
    61321 tttcaccata gggaataaat tcgttatcga tcgaaccata attcgtactg aacaaaccat
    61381 atgtcttgtg atagtcattt ttaggcaaca aatacacggt caaaccgttt ggcagtactt
    61441 catgataaag tgtttcattg atttgctcat attctgtttt attcatttgc atttcctcct
    61501 gctaaaaaga agattgcctg caattcgatt tgctcagcta cttgttgtat ctctttgatc
    61561 gttacgctct ccatacgttt caaccattct tcatcagata attttgtttc cggcagccag
    61621 ctgtccaaaa aagaagcttc gattgccgct tgcggagagt ctagagaaag cagatattgg
    61681 tttctcagca ttgcttttgt ctgagacagt tccaactctg ttatttcacc atttcgcaaa
    61741 ctttctaatt gctcgtgaat cagatgaagt acttgatttc ggttcttttc atcgataccg
    61801 gtttggacac tcatgaatcc tcggaacgta tccacgctac tagaggcata ataagctaga
    61861 ctttctttct ctctgacatt catgaaaagt ttagagtgag gaaaaccgcc aaataaaccg
    61921 ttaaagacca ttagcgcaaa acgttctggt tcatcgtaat acacatttgt ctgataagct
    61981 aggttcagct ttgcttgaac gattggctca cgtacttgtc gttccttcac gatattcact
    62041 tgaggttggg tataaaacag atctggataa actgtttccc gcgactcaaa tggtaattgc
    62101 ccaactgctt cagctgcttt gtccggatca acatcgccga caacaaaaat gtcgatttga
    62161 tcatttgcca tcatttcttg atagtaggac gctagcgaac tagcagtgat cttgtccaaa
    62221 tcttcgacta cgcccaaccc tgggatcttt tgttccgggc tgttttcaaa ataaagttct
    62281 tgcaaggcat aggaagcaaa agtttgttta tcttccttca aactttccaa atatagacgc
    62341 agattgttct tttccaagtc aaacgtcaac tgatcaaact gatgattttt aatatttgga
    62401 taaaataaaa cctcttttaa aaaatctacc gcttgagaaa aaaggtttgg atcattgaca
    62461 tattcaccat tcacaaaact gatccctgcg tttagccaat gtaaatttcc tttttttcta
    62521 actgataatc caaagcttgc gccataaagc tctgcaagtt gcgcacttaa ctttgtctga
    62581 tccgaataat tcaaactatt tgtttccaac atgctgctga gaagtgaacg tttcgtgatg
    62641 acttcttgtt gcagacgcgc agtaaaacgg ataaaaatcc ggatcgtttt gtattgtttt
    62701 gttggtaaga catgaagatt cacgccttct gccaattgat acaccatatt tatatgctcc
    62761 ttttcacagt tgattgcccg cttactcttt taatgggtca acctgccttt tttacttatt
    62821 cctctgcttg aaatttataa gttcaggcaa ttcgccgttt tttctaaatg atgttacact
    62881 ttatagtata gcatagatgt tttttatcaa aagaaacaga cggctaaaag cgtatattgt
    62941 ttttttattt tttatttttc gatatactaa agacaaataa aagaagggag ggtcattcat
    63001 gatcaaagaa ttcaaagagt tcatcatgcg tggagatgtc ttggatcttg ctgtcggcgt
    63061 tgttattggt agtgcgttta caagcatcgt aaaccaagtg gtgcaaggct tgatcacacc
    63121 actaataggt tggtttgtcg caatgatcac aggtacttct gatttagaag gagcactttc
    63181 aattcttgac tggtcgccga caaaaggcgt cacatttgcg tttggtaacg ttattagtgc
    63241 tatcattaca tttctgatca ctggttttgt cttattctta gttgtcaaag cggcaaaccg
    63301 tgcgaagaat ttacgctcca aagaagagca agtggaagtg gaagaaactc ctactgcaga
    63361 agattatctt agtgacatac gcgatcttct tgccaaacaa gtggcagaag acaatacaca
    63421 tccagtagag caaacaaatc tttccgatac ttctaaataa taaagaatct aaaaaaaaga
    63481 aagccgattt tcagtgtcgg ctttcttttt ttagattctt aacttgctac ttgttccttt
    63541 ttcatgtcga tatgtggaat atcatcttcc aaatacacat ctgagattgc cttgaatcca
    63601 aacgactcat aaaaagcttg taggtattct tgtgcgccga tcacgattgg tttttctgga
    63661 aaatttttct ggatcatgtt aatcgtttct tgaacaatct ttcttcctaa accatcttta
    63721 cggttgtcct gatgaacaag gacacgtcca aaatggatac tctccgcttc ttcatatact
    63781 cgcgtgtagg caaggatctt cccatcagta tcttgaaaaa acgtatgcca agcttctcca
    63841 tcaatgtcat caacttcttg ataaggacac tgttgttcca caacaaaaac tgcgattcgt
    63901 tctttgacga tcgcgtaaaa ctctgctgtt gacaattctt caaatttctt tacctgatat
    63961 tccactaagc aaacgccccc tgctttttta ttcttagcat accgattcgc acacaaaaaa
    64021 gcaaacgaac cttacgaatc tcaggctcgt ttgcttttta aactgcttca gttaaaaatt
    64081 cgatctcaac tgtccgagta agtacatctg aatagctgta agatactcgt tcaaaagaat
    64141 tttcttcagg atccaaatca acaacgaata ctgaaggata ggtttctgtt aaaacgccgc
    64201 ggcgttctgt ttgacgcttt cttcctgtct gagcaaccaa catgattggg ctgccgatac
    64261 gaccttctaa atctttcttg attgaagcta aagttgttgg catacagttc acctctacta
    64321 tcaactatac cacatatttt taaaattttc aagtttacca taaaaaaaaa agaaatgcaa
    64381 taaaaataaa taagaagctc attaagattt ttctaaatta ttcctcatta taaaatttca
    64441 agtgtttttt tattttgagt tttactctcc cgtaagcgct cattacttgc ttgtgatcca
    64501 ttgctaaaca ttcagccatg tctacaaaat caacgccttg catataataa tgaaaaattt
    64561 tagcttctat ttttgaaaac tggatttcgc aattttcgat tgcttctttt aataaaagat
    64621 gctgaattgc taaaggttct tgcaatgtga tctctgctaa aaagtctggt ccttctgtct
    64681 ctattttttg gtcgattgag acttcatctt tttgatcacg acgcttcagc gcgttctgct
    64741 tcctcaacag agaatagatt tgattgctta taacgctttt ataataactt ccaaagctaa
    64801 cacctttgct tttttcgtaa gttctcaatg cctgatataa agcgatcctt gcttcttgtt
    64861 cccaatcctc agaaacataa tttcttaaat aataggtgtt tttcaaacgt agtaaaagtg
    64921 gaaaatattt ttgatacagg gcagcaaatg cttcttcgtc accattacgt gcagcgcgca
    64981 ataactcctc agacataaaa taattcctcc ataaattcgt ttatggagga atcttatcat
    65041 caatgattca tcgaactgat tagaacgata tgttatttat tttttctcat taaatcgtcc
    65101 aatttttggg acaatttttt taactgctct tcattccatg gagaattacg tcggaaatca
    65161 ataaaatgca tatctttatt ttcttgggct attgtttttt ccgttttttt tatcgtctta
    65221 tataattcat aagcagaagt tcgtaatgct ccttgggaaa agatcatcca ctgttctgct
    65281 aaatcgcttg tcgccactgt cacttgtgtc aaacggtcat tcagctgacc agcgattctc
    65341 tcgatataac tgtcagccgt ttcgtcttct ttcgtaaaaa caacatccaa ctggtatttc
    65401 ttataatttt gttggatgcc cggaactagt tgggcatcga agacaacgat gacttccatt
    65461 ccttcatatt tcgcataatt tgataaacga tgtaaaagag cttctcttgc atccgccatt
    65521 ttgtcctgct ttttaagctg gacaagttcc ggccacgaac caatcatgtt gtagccgtct
    65581 acaatcaaca gctgtttttt catggtctac tccccctgac gttgggaaaa agcctgatac
    65641 ataagcaaac cagcagcaac actggcattt aagctctgga cgtgcccggt catcgggatc
    65701 gtcagcaatt catccatttc ttttttcaat cctggactca ttcctttgcc ttcattacca
    65761 atgactaaag caattgatcc tttggcattc catttttgga agtttgtgcc ggtcatatct
    65821 gtgccaaata cccaaaatcc tgtttctttg agctgttgca cagcttgtac caaattcgtc
    65881 acgcgtgcaa cagggacatg ttcgactgcc ccagtggaag tctttgttac gataggtgtg
    65941 attccaactg ctcggtgttt tggtatgatc acaccatcga cgccacttgc gtctgctgtc
    66001 cgtaaaatcg acccaaaatt gtgtggatct tcgatgctat ccaaaatcaa aaagaagggg
    66061 tcttcttttt tctcttttgt tcgttcaatc agttggtcaa gggataaata ttcataaggt
    66121 gtaatcgcaa gaacgactcc ttgatgcacg ccgtgatcgc tcaaagtttc taatttttgt
    66181 ttaggaaccc atttgactgg cacagcttgt tcacgtgcga tttctttcag ttcttctact
    66241 ttttctcctc gtgaatcttc ttgaagaaag agtttattcc ctcgcccttg ttgtagcgct
    66301 tctactgcgg catggtgccc aaagacgaaa ttatcttcta atgcttcttc attttgatca
    66361 gaaactgact gatttcgtcc agtttgcttt ttatttgaat atctattttg ttttttgtct
    66421 tcaaatccac gtttcgattg atgtttgttt gttctttctt tacccatttt tttcaccaac
    66481 tttctgaata caccagcgga tcaattcttc catccgctcg gtttgttttg tcaaatgcag
    66541 atagcccatg agcgcttcga accctgttgc gacccgatac gtcgtaacat cagcattttt
    66601 tgcgctcgta tggcttttag catttcttcc tctgcgataa taaagttctt cttcttctgt
    66661 caaaagatgt tcttccagca tttgctgaat caaaaaggct tgtgcattcg cagaaacata
    66721 attcgttgcc gcacgatgca gcttattggg ttttgtttct ccttgatcaa tcaggtggtc
    66781 acgaacatag atttcgtaaa tcgcatctcc aacataagcc aaggctaaac cgttcaattg
    66841 tgtgtaatct ctcatgcttc tcttctccat cgggttcctt gcggtgtatc ttctaataag
    66901 atcccttttt ctttcaacaa atcacgaatt tcgtcgcttc ggacaaaatc acgattgctt
    66961 cttgcttgat ttcgttcttc gatcaattgt tcaatctctt catctaataa ctcttctgct
    67021 gtaaataaaa taccgaagat cgaaagccat tgcgagaata aagcttctcc ttgtgccaag
    67081 acagcggcag aaactttcgg ctggtctaga taagtgttca gccacttagc aagctcatag
    67141 accactgtga tcccatttgc tgcattaaaa tcatcgtcca tttcttcgat gaatcgctgt
    67201 tctaaatttt ctaacaaagc gattttatcc gcatcatctg ccaaattctc tgaggcagtt
    67261 tcttggcgga atttcaaatt gtcaaacgta ttcttcagtc gttgtaaatt ggtggctgct
    67321 tctttcatcg tcgtttcact gtagcggatc ggacgacggt attgtgtggt cgccatgaag
    67381 aaacgcaaga cttgtggatc aacgtttttg atcatttcat gtacagtgat gaaattccct
    67441 agagatttac tcattttttc atcgtcttcg ccaatcgtta catagccatt gtgcatccag
    67501 taattagcga attttttccc tgttttcgct tcactttgtg cgatttcatt ttcatgatga
    67561 ggaaattcta aatcttgccc gccaccatgg atatcgatcg tttctcctaa atgttttgtt
    67621 gccataacgg aacattcaat atgccaaccg ggacgtcctt tgccccatgg tgaatcccaa
    67681 gaaatctcgc caggttttgc ttgtttccat aaagcgaaat ctaatgggtc ttctttttgc
    67741 tgctgttctt cccctgtacg ctgacttgct ccgacttcca gttcatcgat ggattggtca
    67801 cttaatttcc cataattttc aaatttacgg gtacggtaat acacatcacc tgaagattca
    67861 taagcatagc ctttttcaac caacacttga ataaatgcta aaatatctgg catatgatcc
    67921 atgactcttg gatgcagtgt agcaggctcg acattcaacg ctttcgtatc ttcttcaaat
    67981 gctcggatga aacgatcagc aacttctggt gctgtaatac ctaattcgtt tgctgtacgg
    68041 atgattttat cgtctacatc cgtgaaattc gatacgaaat cgactttata gcctcgatat
    68101 tcaaaatagc gtcgaattgt atcgaaagca atggtgctac gagcatttcc gatatggata
    68161 taattataca cagtcggtcc gcagacatac ataccgacat gtcccttttg tatagggatg
    68221 aattcttctt tttttctggt caatgtattg tagattttta tcattctgat ctcctcactt
    68281 tttctccttt gattcgaacg acttttgctg gtactcctac cgctgtagcg tcgtctggaa
    68341 catctttcaa cacaacggca cctgcaccga ttttggcgtt ttttccgatc gttaccggtc
    68401 ctaatatctg cgcattcgca gagagcatgg ctccttgttt aacagttggg tgtcttttac
    68461 ccgtttcttt tcctgtgccg cctaatgtta cgccatggaa taaaatcaca tcgtcctcga
    68521 tttctgcggt ttcgccaatg acgattccca ttccatggtc gatgaacacg ccagttccaa
    68581 tcgttgctcc tggatggatc tcaacaccag ttaggaaacg ccagaattga gcattgatct
    68641 tcgccaataa aaagagccgg tgctgatata aaaaatgaga gaaacgatgc caaaacaagg
    68701 catgaaaacc agggtatgtc aaaacgatct cagctgtcga acgtgcagcc ggatcgtttc
    68761 tctttgctgc atcaatcgct cgggtaaacc aactcatgac tttccactcc tttcgtaaga
    68821 attttatgta ggaaatcatc ttcttataaa gaaaagaagc gccttttaaa taagtttcct
    68881 tatcaaaaga cgctttccgc gtggttccac ttttcttcat aatcaatgat tatctctgac
    68941 agctaacgcc tgttatacgt tcttggctac tttgtttcct ataaaacagt ttttcctgtt
    69001 ttctgtgttt cgccaagacc actcccagag gcatttcggc aaccattcat tgataccttg
    69061 caccacccgg tatctctctt gtaatgatca gctgcttact tttttctgtt catcgtgttt
    69121 agttcagtac ttgatttaaa tgtgctaatg atttttcacg accaagcaat tcgatcgttt
    69181 caggcaattc tggaccatgc atttgtcctg atacagctac acggattggc atgaaaagat
    69241 tttttccttt tacgccagtt tctttttgaa cagctttgat ggcagctttg acagttggag
    69301 catctactac ttccatttgt tctagctgtg ctttgaatgc gtggagaaca gtaggaactg
    69361 tttcaccagc aagtacttct tttgctgctt cattcaatac aggatgttca ttgaaaaata
    69421 gcgtagacag atcaacgatt tctgcagcat agctcatttg aggttgatac aggctaacga
    69481 tcttcttcac ccattcgatt gtcttttcat ctgggttttc tgctacacgt ccatcagcga
    69541 ttagataagg cagacacatg tcagtaaatg catctagatc cattgctttg atgtaatggt
    69601 tgtttaccca ttgcagtttt ttcgcatcga aagctgcggg tgatttactt aggcgttttg
    69661 gatcgaacat tttgatcaat tcttggtgtt cgaagatttc gtcttcgccc acaggtgacc
    69721 agcccaataa tgcaataaag ttgaacattg catctggtag atagcctaat tcgcgatatt
    69781 gttcgataaa ttgcaagatt gattcgtcac gtttgcttag ttttttacct gtttcactgt
    69841 tgatgatcaa tgtcatatgt ccgaaggttg gtggtgtcca gccaaatgct tcatagatca
    69901 tcagttgttt tggtgtattg gcaatatggt catctccacg taaaacgtga gtgattttca
    69961 tcaaatgatc atcgaccgca acagcaaaat tataagttgg cataccatcg cgtttttgga
    70021 tgacaaagtc gccaccgata ttatcggatt cgaacgaaat agcgcctttc accatatctg
    70081 taaatgcgta ttctgtattg cgaggcacac ggaaacgtac aacagattct agaccttgtg
    70141 cttctttttc tgcttgttct tcaggtgtca agttcgcaca tgttcctgcg taatgaggca
    70201 tttctcctct tgcgcgttgt gcttcccgtt ctgcttctaa ttcttcttct gtgcaatagc
    70261 atttgtatgc tcgattgcta gcaagcagct gatcaatcag cggttgatag atttctttac
    70321 gttcagattg acggtaaggg ccgtattctc caggattttc aggagattca tcccaattca
    70381 ttcccaacca agcaaggttt tccaactggc ttttttcgcc atcttcgata ttacgttttt
    70441 ggtcagtatc ctcaatacga ataataaagt ctccatcatt gtggcgggca aacaaataat
    70501 tgaataatgc agttcttgca tttccaatat gcaggtgccc agttggactt ggtgcatagc
    70561 gtacgcgtac tttcgtcatt ttcttcctct tctttcaaac tagactttga ctaacagcaa
    70621 aaattccgtc agttacggct tctcaaatat catttattta aagccactca gcacaaattt
    70681 taccttttct aaggtaaata gtaaagccaa ctggttgaat ttccttacca gttggctgaa
    70741 tttctttttt attttgattg tttagtcttt ttctctgtct cttttttatt gtcgattcct
    70801 cgtcctgcat gtgcaggttt agcaaagatc atgcgtccag cagctgtttg aagggcactt
    70861 gttacaacga cttcgatacg ttcattcatg taatgctgtc catcttctac gacaaccatc
    70921 gtgccgtcat caaggtaggc tactccttgt tggcgttctg tcccggcttt tactactaga
    70981 acattcatcg tttcaccagg gatgacgact ggttttacgg catttgccaa cgcattgata
    71041 ttaagaacag gtacattttg gaattcagag actttattca agttatagtc attggttaca
    71101 atgacaccat ctaaaagctt agccaatttg atcaatttgc tgtctacttc actgatatct
    71161 tcaaagtctc catcgtacat ttcgacagat ataccctctt ctttttgcaa ggcatttagg
    71221 atatctaatc cgcgacgacc acgcacacgt ttcaaactat cccctgagtc cgcgatgtat
    71281 tgtagttcgt aaagaacaaa attagggatc atcaaggttc cttctaagaa tccagtcttt
    71341 gtaatatcat aaatccgacc gtcaatgatc acgcttgtat ccaagatttt atatttatgg
    71401 aaattttctc ctgattttcg ttctaacagt tgactctcaa cttgactagc tgtttcttgc
    71461 tcgatttttt tgcttcgtga accaaaaact ttcttccatt cttcgattcg tgtcgttccc
    71521 attctcaatc ccagatagcc taagatgatc atcagtaaaa tcggcaatac actattgacg
    71581 aatggaattt ccatattgta aagaggggtc gagatcacaa cacctaaagt caatccgatg
    71641 atcgcaccga tcgcaccgaa gagaagataa gtcaagctga cctcacttag tttttgttct
    71701 acttgtttga taatagctga gatatgtttg gccaacagca aagataataa aaagaaaata
    71761 agtgcgccta acaggctgtt ggtaaatgta ttattcagcc atccgtttga ctgttgaccg
    71821 attgcctgcc aagctgaggg taaaaatgaa atacccaagc ttgcgccgac aatgatcatc
    71881 agcaaagtaa tgacacgttt ttgcatcgtt tttcctccgt ttcgacaatc atttattagt
    71941 tagcggaaca cacgcttcaa cgtttcagcc aaagttgcta ctccaactat ctcgattcct
    72001 tttggcgctt cccagttacc taagttgttt ttaggtaggt atacttttgt gaagccgagt
    72061 ttttggactt ctttgactcg ttgttcaata tgactgacac gtctgatttc tccagtcagt
    72121 ccaatttcac cgatgaaaca ttccgttggc tgtgttcctt tttctttata gcttgaagca
    72181 atactgacag cgatagctaa atcaatcgct ggttcattta attttacccc acctgcagct
    72241 tttaagtaag catcttgatt ctgaagaagc aacccagctc ttttttccag cactgccatg
    72301 atcagagata cccgattgaa atcaagacct gttgttgttc gtttggcatt tccgaacata
    72361 gtaggtgtga ctaatgcttg gatctctacc aaaattggac gtgtcccttc cattgccaca
    72421 acgatagcag agccagttgc accgtctagg cgttcttcta agaaaatctg tgaaggatta
    72481 gcgacttctt ccaatccatg ctcatgcatt tcaaaaatcc caatctcatt cgttgagcca
    72541 aatcggtttt ttactgctcg caaaatccga aaactatgat gttgttcacc ttcaaaatat
    72601 aacaccgtat ccaccatatg ttctaacatt cttgggccgg cgatcgagcc ttctttggta
    72661 acatgaccga cgataaaaat ggctatccca tttgttttag cggttttgag tagttctgca
    72721 gtggtttctc ttacttggct gacacttcct gccacacttg tgatgtctgg ctgcgtcatc
    72781 gtttggatgg aatcaatgat aacataatca ggggagatat gttcgatggc acgactgatt
    72841 tcgttcatat ctgtttcagc gtatagataa aattctgtgt tgatacttcc gaggcgttcc
    72901 gcgcgtaatt ttatctgctc tgcgctttct tcgccggata catataagac ttttccgcct
    72961 atggctgcta attgctgaga aacttgtaac agcaaagtgg atttcccgat acctggatcg
    73021 ccaccaatca agaccataga ccctggcacc acacctccgc ctaacacacg gttcagttct
    73081 tctaattttg ttttgatccg aggttctttt ttagggacga cgtctgcgat ttttgttggt
    73141 tttgcttttt ctcctgtcaa acttgtccga gttctgcggt ccgttgtatc ttgttcgatt
    73201 tcttcgacca tcgtattcca ttttccgcaa tttgggcagc gtcccaagaa cttaggcgac
    73261 acatacccgc aattttggca aacaaattgt acttttgatt tttttgccat tgtaccgcct
    73321 ccttttatcc taatcatgag acattaaatc aagcttaagt atctttaacg ttttatttac
    73381 tggaagaacc aaatccgcct tgacgttgag cagtcgtttg atcttgatct gcttttaaaa
    73441 acggcaaaaa gatcccttgg ccgatacgct cgcctttttt gatcactaca tccttgaaac
    73501 caaagttggt gaattggaac atgatatggc cttcatttgc ctcattattg taataatcac
    73561 tgtcaatcac acctactccg tttgtcaaca ctaaaaaccg cttcaacgga ttgcttgaac
    73621 ggttagcaag ctgcaaaaat tcatcttctc ccatgtaagc tttgattcca gtaggcacga
    73681 gggttggttt caattgtttt tcattttctg atacatcttt tttcaatcca tctgcgactg
    73741 tttccaaccc ctttttccag cctgctttcc agatacttgg aatcacgacc tcttctgctg
    73801 cttcaaaatc atagccagca gcatgatgtg tagcgcgctg cggtagattg atattttgat
    73861 ctttatattt agaaataact tcaaatcctc tttttctcac cggttttcct ccctaaataa
    73921 actactccta ttctaacata tccgaggctg taaaagactt tctttacaaa ttcttcaaga
    73981 aattctgcta tcttaaagta aaccattaat tcgttctttt tccaaacgac tgcaagttgt
    74041 acaaaaaaac tattttttac atgactttac tcgtcaaaac aagtagaata gaacgaaatt
    74101 aatgagtgga tatttgattg aggtgtcaca tgcgtaaaga aattaaaaat gcaaaacgaa
    74161 ttattgtcaa agtaggaaca agtacattga tttatcccaa tggaaatatc aatcttgcgg
    74221 caatcgatca gttagctttt gtcctttctg atcttagaaa tcggggaaag gaagtgatct
    74281 tagtctcatc aggagctgta ggcgttggta tgcataaatt acatttgtca gaacgtccga
    74341 ctttgattcc tgaacagcaa gctgcggcgg ctgttggtca agccgaactg atgaatatct
    74401 ataatcaaag attcagtgta tataatcaac agacggcaca gatcctcgtg acaagagacg
    74461 tggtagatta tcctgaaagt cgtaaaaatg tgaggaatac attggaacag cttttgatta
    74521 tggacacgat ccctatcgtg aacgaaaacg atactgtagc agtggatgaa ttagatcatc
    74581 tgacaaaatt tggcgataat gatcagctgt cagccatcat ggcaaaactt gtcgcggcag
    74641 accttttgat cgtcctttct gatatcgacg ggttttattc agataatccg actacaaatc
    74701 ccgaggctca gatgtatcgc tatatcgata aaatcgatga aaagattctg gcacaagcag
    74761 gtggtgctgg tagcacattt ggaacaggcg gtatgcagag taaattaaaa gccgcttcta
    74821 ggatatttga agcaaacagc gcaatgattt tagcaaatgg aaaaaatccg gcaattattt
    74881 ttgatattct tgcaggaaaa gaagtaggta ctttatttaa ggaggacttg aaatgactga
    74941 cttgatgcaa ttaggacaac aggcaaaaga tagcgcgcaa caactagcac ttatgcctac
    75001 aaaccgcaaa aatgagctac ttgttcaaat ggcacaaacc atcaaaaaga atcaacaagc
    75061 gatcattgaa gcaaatcata aagacttaga aaaagcagtc gaaaacaata tcagtgaaac
    75121 gatgcaagac cgcttgcagc tgacacctga gcgaatcaat gccatggcta cagagatcga
    75181 aaaaattgct tcgttagacg atcctattgg aaaagtagat gagatgtgga cgaacaccga
    75241 cggattgaga atcggcaaaa agcgcgtgcc actaggcgtg atcggcatca tttacgaatc
    75301 tcgtccaaat gtcacgacag atgcagctag tctagcattc aaatcaggga atgccgttat
    75361 ccttcgcggt ggcaaagaag cattcttctc gaatcaatta ttagtccaat tattgcagca
    75421 agtactggtc agtgctggcg aatctcctta tgccatccag tttgtcgatg atacttctca
    75481 tgaaactgca ggacagttga tgcgattgac agaatactta gatgtgctga ttcctcgagg
    75541 cggagcaaaa ttaatccaac gagtcaaaga acaggcaacg gtacctatca ttgaaacagg
    75601 tacaggaaat aatcacgtat atatcgataa agaagcacag ttatctatgg cagtgaacat
    75661 catcgtcaat gcaaaagctt cccgtccatc tgtctgtaac gcggcagaaa cattgctgat
    75721 ccattctgag atcgcacctt ttttcttgcc agctattgaa aaagaactgg tagaacacgg
    75781 ggtctcttta cgtgcggatg ctcgtgcgtt agaatatcta gagacggctg ctttagcaga
    75841 agacacagat tgggatactg aatatctaga ttatatcctt gctgtcaaag tggtcgattc
    75901 tttggatgaa gcaattgcac atatcaatcg gcataatact aaacattcag aaacgatcgt
    75961 gacagatagt tatgcggcta gtcaacgttt cttaaatgaa gtggacgcgg cggctgtcta
    76021 tgtcaatgcc tccactcgtt ttacagacgg atcggtattt ggttttggtg cagagattgg
    76081 tatctctact caaaagttgc atgcccgtgg tccaatgggg ttaaatgaat taacttccac
    76141 aaaatatatc atttatggcg atggacaaat ccgcgaataa tgtttcgtgt gaaacattat
    76201 tcccgccttt tgcctttttt ctgtaaaggt tctatccaac tagaaaggtg tcaatatgtt
    76261 tgaaatttta atgatttttt ttatttacct tatttctctg aatatcgctg cttttctggg
    76321 agtcggtatt ttatcccttt tctttcaatt caaaaaacga agcataggga gtcaacggga
    76381 aaaatggtcg cagtattttg acaaaatcgg gcaaaaaggg ctggttacac gcttgcacat
    76441 tagttacatg gttgcattat gcttattagc gacaatcaat tactattctt ttttcgatca
    76501 ttcaatcgct tatacgatta cgctactgat tgctgggatt tttcacttat cttataaata
    76561 tcagctgaat aaaaaccact tgaatcggac tttccgctaa aaaatatccg tacgataagt
    76621 agagtgcctt gaagatcggc aaaaaactgc cggacttttt agaggctgtg acaaagattt
    76681 tgtcacagcc tctttttcca tataaacggc gttcgcctac cagctgcctg gtaaatctgt
    76741 ttcctcttcg ttaagaagcg aaaatccgtc aaatgtttcg ccatcataat aacgaagcag
    76801 ctcatccatg gacaagttca tcgttttttc tttttcttct tccgctgatt cagccagtag
    76861 ctgttcccga tacacctgat acataccagc tattttttgc tgcatcgctt ttctagtttc
    76921 accttccgca ttgattattg gcaattcttt gatatagcca cgataaatca accgatcatc
    76981 tgaaaattca atgggtaatt caacgagtgt caacccgact tcctgaaaat attcttccag
    77041 catctattat ccccccattc tttttcttaa atgaatttta gcttacctac tgaaaatttt
    77101 ccagtttcat tattttgaga aaaaaaggga atgtgacaaa aatcgtgtca catccccttt
    77161 ttccgaataa atgatgttct tctgccaact cctcaatcat aagtcacaat attcaacaaa
    77221 catgagaaac tgttttttga aattgttcct tgtgattcag agttaaacga cagtctcaca
    77281 acctcttggt aaacggcgtt caatcagctg accctcggta ttagctcaaa aaacggtaaa
    77341 atatgagaag ctatttttcc gttttgtttc tctaatactt aggataaaac gctgatttta
    77401 caacctctgt taaacggtgt tcaatcagct gtccttcggt attagctcaa aaaacggcaa
    77461 aatatgagga actatttttc cgtttgtttc tctaatactc aggacaaaac gctgatttta
    77521 caacctcctg ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg
    77581 aaaaatatga gaagctattt ttgtttggct gttcttatga cttgatgcag gacagctttt
    77641 tcacaacctc tgatttctta ttcttcttca tttgtagcaa aataattacg gtgataaatg
    77701 atacaacata cactgataag aacaatggca cctgcaaaat aaaacgcata gctttcacca
    77761 atatgttcac caatcacacc tgcaataaat ggtgctaaag ctccaccgaa aaagcggaca
    77821 aaactatagc tggacgaagc aacgtttcgt tgcagacctg gtatttccat agcaatcgtc
    77881 gtcaacagtg tattgataat tccttggaaa aatcctgcta acacaatgct gatcggtaca
    77941 aggactggca tagaagttcc agctcctaat aacagcaaac aaataatgaa taagacaaat
    78001 gctgctaaaa ttgtccgata agtcgtaaac ttccgctcaa gagccggtgc aacgaaaatc
    78061 gaagcaatag ccagaagcac accccagcca aaaaatacaa aaccgacttc taattcagaa
    78121 tagccaatca ataaaaatgg cgcatacgca agtaaagtaa agaatccgaa attatataac
    78181 aatgcgatta gtccaactga acgaagttta tgattgctta acgctttgac accttcccaa
    78241 aggcctactt ttctctttgg tttctcagtt tcaggtaaaa gtaccgctag ggctataaaa
    78301 ccgcaaaaca tcaaaaatgc taccccaaaa aatggataac gccatgaacc actgcccaag
    78361 accccaccga ctagagggcc aacagccatt ccgcagccaa gtgctgcttc atacatcatg
    78421 attgcttttt ctgtgttacc aactaaaata ctgacgatcg ttgctaaagc agtagagaca
    78481 aataaagcat tcccgacacc ccagccggca cgtaacccaa tcagcattcc gatattccca
    78541 gataatccgc caagaccagc gaatacaacg atgataaaca atcctgtcat caatgttttt
    78601 ttcaaaccga tccgactaga taagaaacct gtaaatagca tcaccacacc agtgactaac
    78661 atgtaactag taaataacag ggtcgtttca gctggcgtag cgtttaactg tgcagcaatc
    78721 gtttttaaga ttgggtctac tagacccact cccataaaag cgatcataca ggtagctgct
    78781 acaactagcg ctgaactttt cccctttgtt tcttcatttg tttgttcttg tatatctatt
    78841 tgattctcca atatttccat ccctttctct ctattagcat catacatgat ttattttaca
    78901 tgtcaatatg cacatgtaaa acgtggaaac tttactgtga tataataaag aaaataagac
    78961 gagaggtagg atttttatga atactttagc ctatatatta ttatgcgtgc ttttatccaa
    79021 accacgttct gggtatgaat tgaagcagct gatcacaatt ttttgggaag cccatcacag
    79081 tcagatctat acaacgcttg ccaagttaga ccagcagggt tatgtgaccg ttttggacaa
    79141 agacgagcac tctcaaaaaa agatctacca cttgactgat gaaggacgtg ctcttgtaga
    79201 ggaatggatc aaagaggaaa ctcccgctcc tacgcaaaaa gatgaatttc tagcaaaaat
    79261 ctatgctttt tcgacgctcg ataaaacaac agctactgga ctgctattca ctagagaaca
    79321 acagctgaac aaaatcatgc aaaaaaatca aaaaaaattg aatgacctct cgctagacaa
    79381 gaaacaagaa tttggacgtt atgttgtgat ccagcgcaga attatgcttt gtcagcagga
    79441 actccaatgg tgtcagcaag taagagaaca aatgcagcag ttttttgagt aagggataaa
    79501 cagaaccttt ctagaaatat ctattgaaga gcaaattatc ttcaataaaa gagcaataca
    79561 gttggaaaag aaaaagcgat ccgaacgaca ggccaaaacc tatcgttcgg atcactattt
    79621 ttctagaact gcattcaaga gactatgaca aaaagcatgc caaggccttt tttcaaataa
    79681 cagtgttcca tcattcatta ctttgaattg cttttagcac acttcttgaa agcgggccaa
    79741 cgatgatcaa ctgcaacggt aaagcggcaa tcacattcat tttccaagca ttcatataag
    79801 cagagaataa ttgatcaggt attccttgtt ccatgatcac accgaataaa gacatacatg
    79861 tcaccattcc taaaaccatc aagcatgaaa tagttaagat catttggacc ttgctttctg
    79921 gatttactgg tagtttaaag gcaatttttt tcgccagcac accgatgatg aagacatcca
    79981 aaatgaaagc caccacgaat ccaggcacta gaccaatcaa caaacttgat aaatgaagat
    80041 cttgatgcag ccataaatta tacgcgctca tccccaagac catcaaaaaa cacatcattg
    80101 ttgtaaaaat tattccttct tttttatttg taggcaatct gtaccactcc tttaaatttg
    80161 tcacgaaaat catcgtagca catttaaaaa tttctcgtaa gtactttttt tattttctgc
    80221 ccttttattt cataaacttc atcagccgta cgctcgacaa agtaagaatc atgagaagta
    80281 aacaaaatcg ttcccggata tatttgcatt agcttctcta aagcttcgat cgttgccata
    80341 tcaataaaat tagtcggttc atctaacagc aacacattac ttggcttagt aaaaagcaaa
    80401 gcaatcgtca gacgggtcgc ttctccccca cttaatgtac ataacggttt cgtcaaagtt
    80461 tcctgagcaa accctaagtg attcagcaaa ctacggacaa gcgattctga aaactctgtt
    80521 tgtctcatga caaaacgaat gatggattct tcagatgtca tttgataacc cttttgctga
    80581 tatacttgaa agcttacttt cggagagaga aggattcctt ctccttgttt gcggatatgt
    80641 tctaataagg ttgtcttacc tgaaccattt tcaccgacaa tcgcgatttt tttacctaaa
    80701 gaaaactgaa aatcaccatt taccagtaat gttctcccac ttctttccaa ttggacattt
    80761 tgtcccatga tgggatagcg gctgtggagt tcaagagatt ttggtactgg aaaacggatt
    80821 tgtttcatct gctgcggctt ggttgtttct cctatttttt ggagtcttct ctctaatgtt
    80881 ttcgcattct tttggatggc tttttgtaca ctgtcttttt gtttagagga agacaaccga
    80941 tccggtctga tttgttgctt tttcttttta ctggacactt tttccaactt ttccgcttgt
    81001 tttttctttt cttggatcga tttttccaat cgttttttct ctttcatgat cgactctgct
    81061 tctcgtagct gagtcttttt ctccaattcc ttttgagtga gataggcact ataattcccc
    81121 gaaaactctc ggatttctcc gtcttttact tcccagattt tcgatgctag ctcatctaga
    81181 aaatagcgat catgactaac aaaaaccagc gtaccataat aataacgaag ctcttcaatc
    81241 agtcgatcaa tactttttct atctagatgg gttgttggct cgtctagaag catcccttgt
    81301 tcataagaag aaagaagacg tatcaactcg atctttcgtt cttcccctcc gctccatttc
    81361 cgctctgaag tttcttccag tcttaactgg aaatgactgg ctaattccaa atttaggtcc
    81421 tttgcttcag cgagataggt taattgaggc aggtagttga aggtgatctc tgtttggatt
    81481 ttcccatgat cgggaaaaag ttcaccggct attagtttga gcaaagtcga tttaccgaca
    81541 ccattttctc ctatgatccc tatacgatct tgctgataga cacgaagaga atcaatagat
    81601 agttctagct ggttgccaaa gctgacttgt agatttgtta tatttactgc taaattttcc
    81661 atatgtttta cactcctatt tcatgtaaaa caacaattat cgatactaaa aaagagcaga
    81721 aaaatctgtt tgcaaaaaaa ctgcatcaca tcttttccta ctctgaacga aataactatg
    81781 actaaatcac caaatctgtc atagctttca cctattctac tgtcgttcga aaaaatggac
    81841 atactccatc catgaaattg ttgtttatac atgtcttttg aatttattta gttgttattc
    81901 aaaagttcga aacgtaattt catcgatgca gtcatttttc cgacctcctt ttttattagg
    81961 ttaccacaca cgattcaaaa aaagcaatag ctactgaata gtaactgaaa accttttatt
    82021 cgaacgtagt gatcttttct ggtgctaaac gaacagactc gtaaccttct tctaccgctt
    82081 ttcctattga taaaataata actggaacat aacggtcttt atccaaacca aatgcctctg
    82141 ccaactgatc tgcttcgaat ccaccaattg gatttgtttc atagccatga tcacgcgcaa
    82201 ctaacatgaa ttgcatagcc gctaagctag aatcgacttt gactacatcg ttcatttctt
    82261 ctcttgaaaa actcttgtaa taaggaatga tcgcagctaa ttgttgatct ctgacttctt
    82321 ttggcatctt ccctgattcg taagcttggt tgtagatttc ttcgccatat tcgtaacatt
    82381 gcatatcgcc aaaaatcatg accattgcag aagaagtatc attttgtctc gtattgaaac
    82441 ggatcaaagg acgcaagatt tcttttgctt cctcgctttc agcgaccaca aagcgccatg
    82501 gttgcatatt gacagaagaa ggtgcagtcg tcgcttcttt gatcatttcc agcatttctt
    82561 cgtgtgggat tttgtatgtt tcatcatata cgcgaacgga tcttctacca gtcataattg
    82621 ttgaaaaatc atttttttgt tccattatta ttaacctctt tcgtttctgt tgttatattg
    82681 caaagttggg tattcaattt atctaaaagt gttagaaatt gtttcatttc tacatcgctg
    82741 aaagccgggg atagcacgga acctgtatct ttatggtcca tttcacaatg cttgattttc
    82801 ttctgggctt tttctgttag cgctacatac acttcccggt tgttctgagg atttctctga
    82861 cgcgaaacat agccatttgc ttccaatacc ttcagatgac gagtaactgc tccttgatca
    82921 atctgcaact tttcttgcaa actgctttgt agcaatggat tttcttcttt cagtctcatc
    82981 atgatctcgt atctagtaag acttataccg atattttctt caaagatctg gacgattttt
    83041 tgatcggcta atttgatttg atataaaagg tgactaatct cttctaaaga cataatttcc
    83101 tcctttctaa taattgactc gtcaacgatt gacttgtcaa taatagaata aaaaaagaaa
    83161 aaagtcaaag aatcagctgt gtaataaaaa aaacgctctc aatagaaaag tatagagaaa
    83221 agaaattttt tgtagaatga acggaaaaaa tgataaagaa agcacaacgc taaaaccaag
    83281 attattgatt cttatcaaac tatagaagat agctcttctg cagtagaaaa ttttacaccg
    83341 ccaaaaattt ccgaaatcgc cttttgcaag aatcccgtcg aatattagaa attggatcag
    83401 tatgcttaaa cagtaataaa aaagttatga caagatgttg tcacaacctt ttttgagtaa
    83461 acggtgttca aaaacttgca tctgcggtaa taagttcaac caaacaaaaa acatgaaaat
    83521 ctgtttttgt ttggctgttc ttactacttg atgcagggca gctttttcac tacctctttt
    83581 taataaccat aaaatcctat tccttcatat ctccagccca tcggtgttag ccaatctctt
    83641 tccttagcac tcaaggtata gtgatgggta ccagtttttt catttggatt aaatagtcga
    83701 taaattggct tggaaccacc agaataaaaa cttagacctt cataacgcca accgattttt
    83761 gttaaagagt tgatctcaga ttgtgccatt gtgtaatgat ggtctccact gtaaggattg
    83821 tataaacggt agacaggttg tccgctgttt ggtgcttgcc aagcaatccc ttcatattcc
    83881 cagcctacag ttggcagata atttttttct ccggcattca atgtatataa atgttctcct
    83941 gtatgacggt tatacagacg atacatcgga gaagttgaag ttggtgctgt atcatactgt
    84001 gtcagattat aggtttcgat tacattgttc aatgtagaac cataattagg cgcagtggca
    84061 taacgacctg ttagccaagc cgtagcatct ttgtaagagt tcgtattgct tttccatgca
    84121 ccggaatagt agtaaacgcc tggctgaaaa gaagtcgtct tcaataccgt tacgttatct
    84181 tgcaatgatt ctttgtacga aggatatttt ctaaaagcgg cattcaccgt aatccattgc
    84241 ccattcacat attccgaagt aggcatcgta acagattggc cattatagct tcctttaatc
    84301 ccaaatagat tgtaattagg ggcagaagcc aaagtactgt tcccccagcc actttcaacg
    84361 atggcttgag caatcatgac tgatgcatat aagtcattgg cacttgccaa actttgtgca
    84421 gttgaggcaa tactatcaat gaacgcttgt tgagaattag cagatgagcg agcataaaaa
    84481 gcatagccag tatagttttc gaattcagac aaatctgctt gatgggtatg tgtcaatgtt
    84541 tgcccatctg tcaattggtt cgtgatttct tctgcattct ctggattgtt ctgagcttct
    84601 gctgatgtac tgtcttcggt ttgtgtttgt tctgttgttt cagttgttgg ttcttcggtt
    84661 gaaattgtat tttctgagac agtagctgac tgcaaagtac tttctgtatc gttttcaatt
    84721 cctgtttctg aagaactcga tgtctgagtt gcgacagttt ctgtcgattc ttcagctagc
    84781 actgttgtgt tggcaactgc tagatttcct aaaagaataa cgctaaataa taaattcttt
    84841 gctttcatct tttttctcct ttgaattatg aaacttttcc taaataacag tgtaactaaa
    84901 aaagtaaaag caagtcaatg tccatattta aataacattt gtttcttttt aataaatttg
    84961 ctttttctgc ataaaaagac gtaaatgaag aatattcttc tccattcacg ccttaaattg
    85021 atggtcgttt gaataactat ttaacaagta attctctctg gatattatcc gttatggatt
    85081 atacttcctg tgtcgtcgga cggataatca tgttgctgac agacatccgg tctggcgttt
    85141 ctatcgcaaa tgctacagca gaagctatat cttcagatgt taatccccat tctttttgcg
    85201 cttcatgaag ttcaagagca gcctttttgt cgctgatggt ttgatataat tcagtttgaa
    85261 cagctcctgg agagatgatc gtagatttga tgttattttg ccgttgctct tgacgtaatc
    85321 cttccatgat tgcacggaca gcaaattttg ttccgcaata aacggcggaa tcaggataaa
    85381 caacatgtcc cgccacagaa tcagttgaaa tgatatgccc agatttttgt ttttccatga
    85441 ttggaagtac ggcggaaatt ccatttaaca cacccatgat gttgatatca agcatatttt
    85501 gccattcatc acggtgacct tcaactaatg gagcggttgg catgattcct gcattattgt
    85561 acaatacatc gattcgaccg aacttttcca tcgctaaatc gataactgct tggacttgtg
    85621 caaaatctct tacatctgct gtttgaatat atagctcagc ttctggtaaa gattctttta
    85681 ttgcttttag gcgatcttct cggcgtgcag ctataactag tttagcccct ttttctgcta
    85741 atagcttcgt tgttgcttca ccgattccgc ttgaagcgcc catgatgaca atcacttttt
    85801 ctgataaatc attcattcta ttctcctcct gttttgaaaa atctcttgct tatactcact
    85861 atctcttatt tcatcttact gttcaaataa tccgttcgac aggtttgacg attttggcag
    85921 ggattcctgc aacgatggta ttgtctggga catctttcgt aacagttgca ttcgctgcaa
    85981 caatggcatt ctcgccaatc gttacgcctg gcagaatagt tgctcctgct ccgatccaag
    86041 catttttctt gatgtggatt ggctttactg acaagcctct tcgttctttt ggatcggtta
    86101 gatggttcac cgtgatgagg ttgacacgag gaccaatcaa tactgaatct tctaaacaga
    86161 tgccacctaa gtcaacgaac atcacttgac gattgataaa gacatttttc cctatactaa
    86221 tatgtttgcc gaaatctgta taaaaaggca gcagaacagt caccgtatca tctactttgt
    86281 cactaatgat attttctagc cgtttgcgga tatctgctgg ttcatggtac ccagtattca
    86341 gcgctgctaa aggctcttcg ttttccgctt ggatctgatg gatcacttca aagagcggat
    86401 ccgttactcg aatctcttta ttgacgattt gtttttcgat gaggcttgtc attttgctcc
    86461 ctccttttat ccttacttta taacggacgg cttatgatgt ctaatactta taaaacatac
    86521 ttaactattc cttttaacta tacttagtgg tatgcttttt taaaaacagg agggaaaaaa
    86581 tggatattcg tatactgacg tattttttag cagtagctag agaaaaaaat atcagccgag
    86641 cagcaaaatc tctgcatatc acgcaaccta ctctctcaaa acaactgaaa gatttagaag
    86701 aagaacttgg tgtgacactt ttcactcgag gctcccgaga gatacagttg acggattctg
    86761 gtcgatatct ttattcaaaa ggaaaagaaa tcttgtcgtt ggtagaaaaa acggcgaaca
    86821 atttaacaaa tgacgcaatc atctctggag aaatctacat tggcggaggc gaaactaaag
    86881 caatctcttt catttctgat agccttcatt cgttgatcaa ggcgcatcct gatatccagt
    86941 ttcatttata tagcgggaat gcagatgata tcatagacaa actggatagc ggattacttg
    87001 attttggact cgtaatcgaa ccgacaaaca aacaaaaata ccagtcattt cgactgccag
    87061 cccaagatcg ttggggactt ttgatacatc ggaatcatcc tttagcaaag caaacagtca
    87121 tccatccgca ggaactgaaa actgttcctt tgatcatttc ccggcaaacg tcagtggaca
    87181 gtcaactagc tgaatggcta ggtttcagca tagatcagtt atcgatcgtc ggaacatata
    87241 acttattgta caatgcttct ttgatggtcg ataacgggac ttttggtgca ttagctctag
    87301 atgggatcat caatacttat gggacggaaa aagtattcat cccactcgat ccgccattac
    87361 aagcttcact gaatctcatt tggaaaaaag accagcctct ttctcctgct gctcgtaaat
    87421 ttttagatgt cctaacggag aaatacagtt aagtagagtt tttttccttc gctttcagct
    87481 ttttaacaac gaataagtta agcaaaagat ccaatgatta aataacataa gtttcttaat
    87541 ttgttccttc cttttatttc tgataattcc agtaaattac tataattata aaaaaagaat
    87601 tgacaaaaca taactgtcta tataaaattg attacgttaa caataattcg tttcatgtga
    87661 ctagatcata ctaggcatga aaaatctctg aggaacatgg tttccctagg aggtttttcg
    87721 tgtctatttt tgtttggccg caatcaactg gtctagcaaa cgtgaaaacc aaatcttcaa
    87781 aaagggtgcg cgcatgaaaa tcaaaaagat ctttaatcaa aatgcagtat tggtagatga
    87841 cggtggacag gaaaaagtag ctattggaaa agggattgga tttgacagaa aaagaaatga
    87901 tttgattttt gatcgtgatg tcgaacggat atttgtcatg gaaccagaag gtcaaatcaa
    87961 gttgcaaaat ttacttaatc agattgatga acgcttttta tttgcagcag aaacgatcat
    88021 tgatcatgcg gaaactgttt tgatggaaaa gttgaatgaa catgtattga tcgctttgac
    88081 cgaccacatt gctttttctg cggagaacat taataacggt atcgtcatcc gcaacaaact
    88141 tttaagagaa atcgaagtgc tttacagtga tgaattcagt attgctcaat gggcagtaga
    88201 gtatctgaca aaagagcttg ggattccata tacttatgac gaagcaggat atatcgcaat
    88261 ccatattcac agcggacgaa gcggtcggaa caataaccat cgcagtatcc gtgaagtgac
    88321 gattgtatct gacatcatcc atttagtgga atcagaattg gaaacagata tccattcaga
    88381 accattttca ctgaattatt caagactggt gaatcattta cgactgcttc tacaacgaac
    88441 ccatgcgcaa caatatgctg ttttagacac ggaaatcgta gaaatggtca aacgaaaata
    88501 cccagaaagc tataagattt ctaaaaaaat ccgtgtgttg ctgaccaaag aataccagct
    88561 cgcgatcacg aaagaagaac tgggttactt ggccatccat atcgagcgtt taagaagcgc
    88621 aatcgtacaa acaaatgtta acaatcatga ggaggaaaaa aattgaaagc atatctacaa
    88681 cgaatgggac gttcccttca acttccagtt gcggtcttac ctgctgctgc tttactagta
    88741 gggatcggaa actggtgggc atcttatagt aacgacattg tcgctcattt tttacaagct
    88801 ggcggtaacg cagttttagg tcaattacct ttgctgtttg ccgttgggtt agcactaggg
    88861 atgtcagtgg acaaatcagg tgctgctgcc ttggcaggtt tggtcgcatt tgaagttcca
    88921 gtaaatgttt taaaaactga ttcagtagct actttattga atatcaaacc agaatcagtt
    88981 gatccatctt ttgctcagat cagtaacgta tttattggta ttattgccgg attgattgcg
    89041 gcagctcttt ataatcgttt ccacgaagca aaattaccga tggctttatc tttctttagc
    89101 ggcaagcgtc tagtgccaat cttggctgcc tttgtcatgt tgctgatcag tgcagtgcta
    89161 ctgctcgtat ggcctccggt ttactctgct ttagtttctt ttgctaaatt cattttgagt
    89221 ttaggctggg gtggtgcagg tctttatggc ttcttcaacc gtttactgat ccctacagga
    89281 ttgcatcaag caatgaactc cgtgttctgg tttgacgtag caggaatcaa tgatattggt
    89341 aaatttttgg cttctgaagg aacaaaaggc gtaacaggaa tgtatcaagc tggatttttc
    89401 ccaatcatga tgttcgggct tccagcagga gcatatgcta tttacagaaa tgcacgtcca
    89461 gaaaacaaag caaaaacagc ttccttgatg ttagcagcag cttttgcttc attctttact
    89521 ggtgtaacag aaccacttga attctcattt atgttcgttg cttggccatt atatgtcttg
    89581 catgcaattt tcactgggat ttctttagca gtgagtgcat tcttccattg gacagcagga
    89641 tttgccttta gtgccggatt tgtcgattac ttcctatctt tgaaaaatcc gattgcgaat
    89701 cagccattga tgttgatcgt ccaaggatta gtaacagcag tgatttacta ctttggcttt
    89761 aactttgcta tcaaaaaatt ccatctgatg actcctggcc gcgaggaagc agatctttca
    89821 gatgacgata ctgcaacgac taattcagac aataaatatg cggcacaagc aagcaaaatc
    89881 tacgctgcat taggcggagc cgacaatgta acttcgatcg ataactgtac tacacgcctt
    89941 cgtttgcaag tcaaagatac aggcctgatc gatcaaaata aaatcaaagc cactggcgta
    90001 cctggtatga agatcatcga cggaaaaaat gcgcaagtca tcgtaggtac agaagtacaa
    90061 ttcgttgcag atgagatggc aaaactacat ggtggtgctg caacacgacc tgcacaaaca
    90121 aacaccgtgg ttaaaacaga aacatttgcc ggtggaacga tcgaacaaga tatttacgct
    90181 atcgcaaatg ggaaactgat tccaatcact gaagtttcag atgatgtatt cgcggaaaaa
    90241 atgatgggtg acggctatgc tgtattacca gaaaatggag aaatcttctc tccaatcgct
    90301 ggtacgatca caaacatttt cccaacgaaa catgctgtcg gaatccaaac agatgctggt
    90361 atcgaagtct tgcttcatat gggcatcaac actgttgact taaaaggcga accattcact
    90421 ttatatgtaa aagaaggtca aaaagtcgca agaggtcaat tgattgcttt agttgatctt
    90481 gccgctattc aatctgcagg caaaaacacg gatatggtcg ttgtattcac aaatggcgac
    90541 aaagtccaaa gcttagaaat cgaacccgca cgtgatgtaa aagcaaatga taaaatcggc
    90601 tctgtttcca acaaagcctg agccatcgtc ttccccagac ttttttatcg ataaacaaac
    90661 aggagctgag acaaaaatct tgtctcagct cctttttccg aataaaaacg gcgttctcct
    90721 gccaactccg cggtaataag tccagccaaa cgtaacatat gaagagctat tttttatttg
    90781 actcttctta ttacttgatg cagaacagct tttttacaac ctctgataaa cggtgttcaa
    90841 aaaccagttt atcggtatga agtcaaattt atgcaaaaat gtggaaagcc attttcacaa
    90901 aatttttctt catactcaaa actaatcggc tttttcacaa cctctttata cattattcct
    90961 gatccaatat ttcttttaat gctgcttcaa gagaagttaa tggttttccc aatacttttt
    91021 ctaaatcatc agaggaaata gctaactgat cctttttaat atcatgttgg atcgctaaaa
    91081 acatgtcagc tgcttcttga gggaatccgg cttcttttag attttcgaca aacgctgcat
    91141 cacttgcttc aataatttct aactttttac ctgtcgcacg ctctaatgcc ttggctaatt
    91201 cttcatagtc agttagattg ccggataatt ctaagatttc tggagagtca ctttctacta
    91261 gtacttttgc tgcagcttct gcatattcac gtttcaatgc ccaacctgtt tttccatttc
    91321 ctgcagcata aacgaattga ccagttttta aagcctgccc aatgataggt aattcattct
    91381 ctacatacca attattccgt aaaaatgtat gggaaatacc tgaatcctta atcatttttt
    91441 cagtgaattg gtgatctggc gctaatacac tgatcgagtg atcggcatct gcaaaacttg
    91501 tataagcgat ataagatacc ccagctgctt gtgctgcctt cactacattc ttatgttcgg
    91561 cttgccgatt tcctggaacg ccagagacaa aaagcaatcg atctattcct ttcaacgctt
    91621 ctttcattga gtctaaatca tcataatcac caatacgtat attaaatcca gcttctttca
    91681 gtgcttctcc tttttcttca ctacgtacta gtacatagat ttcattttgt ggaaccatct
    91741 tttttaagaa ttccagcgca taaccaccaa aacctccagt tgctcctgtt actaaataat
    91801 gcatatttgc cactccctat tctttttatt tgttaagatt tacagctgta catttataaa
    91861 ttacaccttt atcataaaga gtgtggtaag ataagtcaag caaaaaaaat gaaaggatga
    91921 caactgatga agtattctct gcaatttagt gatgcaatcc atgtacttgc ctatattgaa
    91981 atgtttcaag atacccgatc actttctagt gagatgattg ccagtagtat cgaaacaaat
    92041 gcagcaaatg tacgtaaaat catgagtcag ctcaaaaaat ccggtttgat ctttacaaaa
    92101 accggaaaac cgcagccttc ccttgccaaa agtccagatc agatttcttt actagatgtc
    92161 tatcgcagca tcgaaggtaa tacacagctt atccaagtcg atccaaaaac aaatccaaat
    92221 tgcgtcgttg gtgcgaatat ccaagaagct ttagaagaaa gctacgctcg gctgcagaaa
    92281 aaggcagaag aagaaatggc taagatcaca cttgatagtc tgatacataa aatagccgtt
    92341 ttggaaaaag aaaaaagacc agaaaacaca ggcctcgtag agagattttt ataattctct
    92401 ctactgtgcc tgcatttttc tgatcggaat cgtctacata aattctttta ttctccgggg
    92461 gacaaaagcc ttgtcatgcc cctttttcct ctctaatgct caggtcaaag cgctgaagtc
    92521 atgacgtctt gataaacggt gttcaagtag ctgaccctcg gcattagttc tgaaaaatgc
    92581 aaaatatgga aagctatttc ccatttttcc tctctaatgc tcaggtcaaa gcgctacttt
    92641 cacgacctct atattatcat ggtttattga ctaccggtat ccagatttct cccatatatt
    92701 tcccgttggt aactcccatt tcgactacag catttggacc cccaacatag gcgtaatctt
    92761 ctacttctct taaaacatgc ccaaaggccg tattcgtcaa atcatttctt aattcttcag
    92821 gcgattctgc taaagcgatt acaacaagat acgttccttt tgggaatggg atgattcggg
    92881 tagtgtttgg aacatcctga ctcgtttgaa caccgacata gtacatcatt ttcccgttat
    92941 agggttcgtt gactgtaaag aaataatgat tttcagcagc ttgtttcaat gcatctattg
    93001 ttccattacc gataactttt tgctcaaatg cttgtttctc tgcagccaaa ccgacaaaat
    93061 ccgtattgct actcttcaat tccacaccaa tacccgtcac cgtaaaatct ggtttttctt
    93121 cgatcctata ctttgccatt tctcccaccc tttctattat attaagttca tcttacataa
    93181 aattaaaggg aaatgacacg attacgctct tttttctagg gatattttta ttttttaact
    93241 atttttttgc tttcactgca atccaaatct cactgtaaac attactgaaa tcctctcccc
    93301 attttgtaaa agagatctcg ggagcttcga ctaactcata atctgaagaa ggaagccatt
    93361 ctgcatagat tttcccccaa gtatcttgta aagtttgggg aaatggccct ttattaggaa
    93421 aaatggccca agtgtgttct tctatagcaa gcatttctaa atcagcgtac ggattttctt
    93481 ttgtcgtagc aaagccaatc atgtgcatca aactgccctt ttcttccaag cgggctccat
    93541 caaatccata agaaacgttg attacttgat ttggatataa atctcctaac ttatgcatct
    93601 cttccctttg agtctccgtg atcgtctgcg ctaacttttg tatttcttga ttgactcctt
    93661 caaatttgac aggaactttt ttcgccacac ctgccacata aaactgttct ttcttttcga
    93721 tacgaaattc catcgatttt cctcctctga catcaataaa aaatgtcaag cgtggaaaag
    93781 atttttgtat gccgtatctg ctgatttctg aaggcagata tcctgaccaa tcacgaaaag
    93841 ctcttgaaaa accttcgact gtttcatatc catatctaaa cgccgtttct gtcactcttg
    93901 atccatctag gagatcgcga ttagccaaag ccaatctacg gtttttgata tagtccatta
    93961 gcgacatccc tgcaataaac gtaaagatgc gttttaattg atattcagag attcctgtat
    94021 tttcggctat tattttatag gaaagtcctt ctgtcaaatg ttcttcgatg taatcgatca
    94081 attggttcag atctttaagc atatttatct tcctccttgc ttgccttttt atcatattat
    94141 caaagaaagt caattacttg atgaatcagg aaccaattta gtcagatgta gaaaatgttg
    94201 tatggatcta aagaaaattc tcaagcagcg tttcgtaacg gataattggt attatctgcc
    94261 tatctatgtt ttacctttag aaaaataaat tttggggaag acacattcta agtaaacaaa
    94321 gcggtaaaaa tatcttttat tcccttagtt aatccgctta ctacctactg tacaaagcaa
    94381 attgttgttc aaactgctga tcagaacgct gcttggattt ttctttgcga tacatcatac
    94441 ctcttttatc aattggaaca attatttatt tctaacaaaa tcacttcatt tttgtcagat
    94501 aaataaaaaa caaaaaaagt tccatcttta aaacacgcta ttcttttact ttttctcaca
    94561 ttctctaaga aaagaaaagg agaatgaatt tttgacaatt cgagcaaaag tgattatcaa
    94621 atatgtaaaa tcagctactt ttttcttaaa cgtttcttta tactaaatat aaataagtgt
    94681 ttcatgaaag gagaactaga tgaataattg gcttgagtat tttcctgaaa acgttttgga
    94741 acgcggttac agctatcatc tgcacggttt tgtccgtcat ttgaactata caagcaagta
    94801 cttgtccgca acagtttctg gcacggaaga ttataaggta gtgatcactt gggatgaaaa
    94861 gaccaacatg acttgtgatt gtctatatgc catagaagga aaaaaatgca aacacatggc
    94921 tgctgtctta ttcgcttacg aagaacgtcc aataaaaaaa tccaactact cactttccga
    94981 actctcgtcc cttgtttcct ccgctagttc ctctcttgta cgggagcttt taacagagat
    95041 tcttatagaa catccgcaat ttatcgaacg cttcaaagtt aagatgccat ttcatgcaat
    95101 aaattattca gataaattaa caactatcat ccataaatac gatcatatta tcaagaaaaa
    95161 caaaaacagg aaaacagcga agttcatcat ggagatgcga aagttcatcc aagaagcagt
    95221 tgaatcgctc attcagcaaa atgcctatct tcccgcattc gaattgatca atgaagtgat
    95281 tgctactctc gaaacattct attgggagcc tgaggatgaa cgaacccttc ttctgataga
    95341 ggactgttat tatttatgga aagaattatt agcagaagca cctcatgcag aaaaaaggca
    95401 aatgttctct tggttcgtct gccaagtcga tcatactgac gcctcttatt caaaacgcta
    95461 ctccataaaa atcctgaaag aagactttcg ggaaaaagaa ttttctaacc aaaagaaaaa
    95521 aatagataaa aaaactaaag aaacggtaaa gaaagacgat ttcaatgaaa aatagcaagt
    95581 aaacgataac aaccatccta aatccacaag aaatacagca gaccttgctt taaaaacacg
    95641 aatcatgcaa aggatgaagt aaagaagact taacgcgtac ccaatattag tcatttgact
    95701 attaggtacg cgttttgttt tataagtcat gacaaatttc cttcgttgct gggtagattt
    95761 tccggcattg ttgatagatt ttatgatact tttctacatt ttgtaagaga ggttccactg
    95821 catctgtata ttggataaaa ttctgacaac aactttcagg tgtgtcgaac cactctaatc
    95881 tttaaagata aatattaaaa taacgattaa taatattaac agtctttatt tttcaccacc
    95941 aaaaacctat ctttgcatat actaaataga cgtatataca cagataggtt tgtcttgtga
    96001 aaaataatga ttatccttac caaaaaatgt ttgtttttct acatgttcgt acttatcaaa
    96061 aaatatgatc cttattgaaa ttactggcta tttatattcc aacgacttct tgtgttaatt
    96121 tttgttatct catagtaaat tatgtttcat tttcacttaa tttagttgtc acgtgttcgt
    96181 caattcgtaa aaacggtaaa tatataaaca cacttgcggc tataattaat atttgtaaaa
    96241 cagctgctcg ccagtctccg gctgttgcta aaaatcccga tataactggt ggcgtagtcc
    96301 aaggaatttg cactactaca tgattaatta atcccacagc agttgcaaaa tatgctactg
    96361 tcaaagaaaa aatcggtgca agcacaaagg gaataatcag actgatatta aatacaatag
    96421 gcaatccaaa aataataggt tcgcttatat tgaatatagc gggagttacc gataatttag
    96481 caaagtcctt ataatctttt ctacgactga agataaatat tgcaatcaat aaagcaatcg
    96541 tatttcccga tccacccatt accgcaaagg tatctttaaa ggccatattg ataatatgtg
    96601 gaatttgctc tttgtttgca taagctgcca tattttcttg catattctga atcaaaaacg
    96661 gatctaacaa tgaacctgat attactgctt gatggatacc aaatccaaaa aatagattag
    96721 caatagatgt aattaacaaa aatcctggta aaccagttgt aattttactt aatggctctg
    96781 taactatcgt ggtaattagc ttatttatat ccatattaaa caattgaatg attataaatg
    96841 acaataaagc aaacgaggta atcgtaataa tgattgggat taatacatta aaagacttta
    96901 aaacagcggg aggaatattt ccggatagct gaatctgtag tttcttatta ttagaaagtt
    96961 taataaataa ttctgtagcc gctaatccaa caaatatacc tacaaacatt cctgaagctc
    97021 ctgtatagga tataggtatc acacccgtca cttcaacagc tttatccgca ttttcaggag
    97081 taaacatcat ctgcataggt gttaatacaa caaatgtcga aatagcaact aataccgctg
    97141 caatatgatt tgtataattt ctgcttgcac acatatgata agatactgct gctacaacta
    97201 ataatgtagt tatgcttaat gtaccattgg caattgaagt accaatttgt tgtaacgtgg
    97261 tcaatgtact agtatcgaca atttccccca tgaatcctgt tggttctaag atcactgaat
    97321 taataagtgt cacaaatcct gctaacatca taaatggcat aaatgtagca aacgcatctc
    97381 gcaaagttct taaatggatc tgattcccca acttagtcgc aactatacca aatttttcaa
    97441 atacaatgtc cttcctgcta cttttgccca tattttttct cctttatgct tattgtaatc
    97501 gattactttt tccacccaaa taatacatca cttatcaaaa aaagtaaata cttttaatta
    97561 aatatatata tcttttttag tataaaaaaa taagctctga aaaaataatt ttcccgagct
    97621 tatttttcaa caaaaacagc ttcaaaaaca aagtcttgat ataaatgtct cgataccgaa
    97681 tactcgaaag gtttaccaga cgatagagca acaactttgt ctatctcaat cataaattca
    97741 cctggatcta tttttaatat ttttgcgtca aattcattcg cagtatctcc tttgatacgt
    97801 atgtgcgaag tctttatttc cagacccagt tcatttgtga tataagcata tacagatttc
    97861 tttaaatgtt ttggttccaa gcctggtatg actgctaatg gcatgaatgt ttgctcaatc
    97921 gagtatggtt gacaatcaat aaaacggctt cgtacaatat tatatacata gtcttttaca
    97981 ctgatactta atttatcagc tacttttttc gatggaagtt caattgagaa agtatggatt
    98041 tctgaatcta cgtgttcttc accaaccacg ctaaacaaac cttcgtttgg accaagaact
    98101 cgtgagttat caattggtgt tctgacgact tcagtcccat acccacttct acttcgcaaa
    98161 actccttcgg aaacaagtaa gtctacgcct ttctttactg ttaacttgct tgtatgataa
    98221 ataactgcca attcatctcc tgtaggaagt ttctcaccaa ttttatactc tccatttaca
    98281 atttttttct ttatatctaa gtaaatttcc atatacttcg caattttttt caatggtgac
    98341 cctccaatca aaaacatatc ttcatctata ctttaacata aataaaccga taaaatccac
    98401 atcaaaatta tacacacaat aaaaaagata tatatattta aacaaaacta tttactttaa
    98461 tttgtaagcg gtgttatcat taagtggaaa caggaggtaa aaaaattatg acaactatga
    98521 aaaagctaac ttttccagat gatttttggt ggggttccgc ttggtcatct gagcaagcag
    98581 aaggaaaagg agaaacagga aaagcagaga ctatctggga tcgctggttt aaagaacaac
    98641 cttaccggtt ttatcaacga atcgattcct ctattacaac cgatcacatc catcaatata
    98701 aagaagatat agaactaatg aaaaaaactg ggcataactc ctttcgcgtt tctatttctt
    98761 gggcacgaat gtttccaaat ggcggtaccg gaaaagtaaa tcccaaagcc atttctttct
    98821 atcgaaaatt attttccgaa atgaataata acggaatcaa agtatttgcc aacttatatc
    98881 attttgacat gcctgctact cttcaagata aaggaggatg ggaatcacgt gaagtagttg
    98941 atgcttatgt tcattacgct gaaacttgtt ttaaagaatt tggtgactta gtttgtcatt
    99001 ggtttacctt caatgaacca cttgggccta ttttaggtac ttatcttgaa gattttcatt
    99061 atccaaacct cattgacttt aaacgcggag cgcaagcagc attcttcact atacttgcac
    99121 acgcaaaagc aatacaagta tttaaagaac tagctcttcc tagtaaaata ggcgttattc
    99181 taaatttgag tcctactttt cctcgtagtc aaaatcctgc tgatgtgaaa gcagcagaaa
    99241 tcgctgattt attttatacg cggagctttt tagatcctat ggttaaaggg aatttttcta
    99301 aaaagcttat cctgttatta caagaatata atcagcttcc tgaagattat acgaaagaag
    99361 atcttgtatg tatctacgaa aataccgctc aaattcttgg actaaactat tacgagccac
    99421 gtcgcgtcaa atctcgttct tctatggtgg atacatctag tccattttta ccagagtggt
    99481 ttttcgaacc acatatcatg cctggacgac gaatgaacga ataccgggga tgggaaattt
    99541 acgaaaaagg aatttatgat ttgtgcatgg atatcaagaa ccattatgga aacatcgaag
    99601 catttatctc ggagaacgga atgggcgttg cggatgaaga acgtttcatg gatgatacag
    99661 ggcaaataat tgatgattat cggattgagt atatcaaaga tcatcttgct tacttatgga
    99721 aggcaataaa tgaaggatgt aacattaagg ggtatcatct ttggacattt attgattgct
    99781 ggtcatggat caacgcctat aaaaaccgat atgggctggt ttcactcgac cttactactc
    99841 aaaaaagaac aattaaaaaa agtggcgaat tttacaagca attaagtgat acaaatggat
    99901 ttagatacga tgtagacttg ttagttgaat aatattctaa aattccactt gaagtgaaca
    99961 cattagaaaa caagaataat gagaaatacc aataacaaat actttttctt catacttcat
   100021 ttatacttgt cagtataaga gactgtgaca aatgtagtga tcctcagaag ttaggtctgg
   100081 aaatctaact tgagaagatt tttttaaact acgtccagtc ttttttattt gtttaaaatt
   100141 gaagttgaca agtcttcatt aaaaatttag aatattcaca agtttgacga caattatgaa
   100201 aatttatgtc gtgctaaagg agttttgtta ttggatgaaa agttagatat aaaaactgcg
   100261 atcaaagaca cgttacctac cgtttttggt tatatcggta ttggacttgc atttggtatc
   100321 gttgggaaag ctgccgggtt tcatccgctg gtcgtcacgt tgatgtccct gctgatctat
   100381 gctggttctg cccaatttat cacggtcagc atgcttgcta gccatagtcc actgctctcc
   100441 atcgttctct cgacctttct agtcaattcc cgaatgattc tgatgagtat gacgattgct
   100501 ccttatttca agaaaaatcg gctgcttcaa aatctgctga ttggcacatt gctgacagat
   100561 gaaagtttcg cactgggaat gaataaattg aactatactg gacaaaagtt aaactttcgt
   100621 tggatgaata cagctaattg gatttcttat ttgacgtggg tgggttcttc tcttgttggc
   100681 gcacttttag ggaattttat tactgatccg aaaaagtttg gtttggattt cgccatcgtc
   100741 gctatgttta tcgggttact ttatcttcaa gtcatttctg atagaaacac ctctaaacga
   100801 ttacagttga tcctgattgg tctcactttg attctggtat atgtcggact gatttttatc
   100861 ccaagtaact tagtgatttt agttgtaaca ctgattgggt gcggattggg ggtgtggatc
   100921 aaacatgcct tcttttgagt ttacattgct gactatttta ggttgtactt tagcaacttg
   100981 gctttctagg atcctaccat ttgtcttact gaaaaaattc gatttgccgc aaccgttgct
   101041 tgagtattta agttttgtcc cgatcgtcat tatgtctgct ttatggttca gcagtctatt
   101101 tacccaaaat atcggacatc tgccgcagat caatctcgaa aatgctttgg cttcagttcc
   101161 tacactttta gctgctattc tttcaaaaag cttattggtg atcgtcttgg taggaattct
   101221 ttccctttcg ttgattcgct tattataaat aaaaaaacaa gagcttatgg caaattactg
   101281 tcatgcgctc ttgtttttat caaagtcaaa taagaaaaaa atcggcgtat tcttgcttat
   101341 ccgttgaacg gaccactaac aacgactttt cctaacatat gtcctgtttc tacgtctttg
   101401 gttgcttgtt tcaagttctt cgcattcatc ccatctgaat agaccttgct caatgtactg
   101461 cggataatcc cttcatttgc taaagcagca atgtgcgcta aagcttctcc ttgcgtttcg
   101521 atttcatagt tatagtctgt tttagcgaac atatactccc agtcgaagct gatagattgg
   101581 tttttccaaa cacctatatc taacggctct ttgatcccta cgatcgttcc cacatgtcca
   101641 aatggtcgga caaggtgttt gatttgatca aagtagcggg taatatcgaa taatacagcg
   101701 acatactcta cttgatcgat tcctaattca cgaaaacttt tacttaagtc gtgatgataa
   101761 tcgattggat agtctacacc tgtttttttc agccattcaa aattcttcgg acttgcagtc
   101821 gcgtagactt ctaggccagc ccaatgcgct agttgattca aaatcgaacc gacgccccca
   101881 gctccgttga tcactaagat ttttttcccg cggttggcat tttcttctgg agtcagacca
   101941 aatttttcaa ataacaattc ataagcggtc aatgaggtca acggcaaggc tgcggcttct
   102001 tcatctgaaa gattttttgg tgcaagagcg acaatacgtt cgtcaaccag ttggtattct
   102061 tgattgcttc ctgctcttgt cgttgtacct gcgtaaaaaa cgcgatcgcc gacagaaaat
   102121 ttttgcactt catcacctac agcaacaact ttcccgactc catcaaaccc taagatacgt
   102181 aaagcatttc ttatcccgtt atcttggcga agtttcgtat cgacaggatt aacagatact
   102241 gcgttgactt ttaccagaag atcccgtgaa ctgggtacag gtatctgttc tttttcatca
   102301 ataaagcttt ttggatcatc gatcgacaac ccttcataaa aaccgactac cttcattaat
   102361 tccttttctg acatacgaat tcctccttag cttcatcaag ttggagcatc catacagttt
   102421 tcatttcaat atatatagta tgctatttgt tccactttta ttcatcataa ttattctctt
   102481 acttaaagta aactatttgc acttttttgg ttaaaaaaga ggttgcgaca agacttttgt
   102541 cacaacctct tttaaacggt gttcaatcaa ctgaccctcg gtattcgctc aaaaaacgac
   102601 aaaatatgag gagctatttt tgtttggctg ttcttattac ttgatgcagg acagcttttt
   102661 cacgacctct aattcacggt gttcaagcaa gaaatcattg ttcactgaaa agcgttggat
   102721 gttctttttc aaaggtgtct aagatctctc gtacttcatc agtagatttc gtattcatca
   102781 actgaactcg caagtcattt gctcctggaa atcctttgat atagatttta aagaaacgat
   102841 gtagtcctgt gatggaacgc gggatgattt ctgaataatg atcttgcaga tctagttgca
   102901 gacgaagtag tccgatcagt tctttttctg tatgttccct cggttctttt tcaaatgcat
   102961 aaggattctt gaaaatcccc cggccaatca tgatgccatc tacgccatat ttttcggcca
   103021 attcttctcc tgtctggcga tctgggatat ctccgttgat cgtgatcagt gtttgcggag
   103081 cgatttggtc acgtaaagca atgattttag ggatgacttc ccaatgtgca tctactttac
   103141 tcatctcttt acgcgtacgc aaatggacag aaagattggc tatatcttga tgaagtaggt
   103201 gactgatcca ttcttccatc tcagacattt ccgtatagcc gatacgcgtc ttgacgctga
   103261 caggcaaacc gccagcttta gccgcttcaa tcaattgtgc cgctacttct gggcgaagga
   103321 tcaagccact gccttttcca cgttctgcta cattagggac tgggcagccc atgttgatat
   103381 cgattccttg gaagcccatt tctgccatag caatgctcat ttctctaaaa aattctggct
   103441 tgtctcccca aatatgggca accatcggct gttcatcttc tgtaaaggtc aatcttcctc
   103501 gtacactgtc ttttccatct ggatgacaga aactgtctga gtttgtaaac tcagtaaaga
   103561 agacatccgg tgctgctgca tgctttacga catggcgaaa tacaacatct gttacatctt
   103621 ccattggtgc taaaacaaaa aaaggctttg gcagctcttt ccaaaaatta gtagtcattt
   103681 atttgttact ctccattcta tcaagcagtg aagtcgcaat ctttctcaaa aacattgtca
   103741 ttatactagg aaacaaaaaa agaagcaaag tgaacagctt aaaagatgtt tctgattgag
   103801 caaaaaaaga ctgtgacaaa aatcttatca caattccttt tccggaataa atggtgttca
   103861 aaagcttgca tctgcggtaa taagtccaac caaacgaaaa ataggaggag ctatttttgt
   103921 ttggctgttc ttattacttg atgcagaaca gctttttcac aacctctcca ctaaacggtg
   103981 ttcaatcagc tgaccctcgg tattagctca acaaacgaca aaatatgagg aactattttc
   104041 ccgtttgttt ctctaatact caggtcaaaa cgctgatttc acaacctctt ttctaacttc
   104101 tcaatcctct tcctttattg atcaaatacc aagtaacggc gtacaaaaca acgatgaata
   104161 gcacaagtac gatcatcgat gttgctactg gcacatcgat tgttccaagg aatccgtaac
   104221 ggaaaccgga gatcatataa acgatcggat tgactttcga aacagcttgc caaaatggcg
   104281 gcaacataga gatggcatag aaaacgccac ctagataagt taacggctgc aagacaaatg
   104341 taggcacgat cgatacatca tcataagact gagcaaaaat cccgttgagc agtcctgcta
   104401 acgaaaacaa gattgccgtc atcaataatg taatgatgac catgaaccat gaatacacat
   104461 gaagtggtac aaagaacaag gaaatgatcg ttacgagaga gccgacgaga atactgcgac
   104521 ccactccgcc aatcacaaag ccccaaatga tcacatgcgt aggaacaggc gctaccaaga
   104581 tttcttcgat gtttttctgg aatttttgag agaagaagga cgaagaaacg ttggcatacg
   104641 aactagtgat agcagacatc ataatcaaac caggcacgat gaattccata tatgaaaaac
   104701 cacccatgtc accgatccga ccaccgatca tttttccgaa aataacaaag tacaaggatg
   104761 tcgtgatcac aggcggaacc agtgtttgga cccagatacg caaatagcgg ttcgtttcct
   104821 tgatagctaa actttttaat gcagtaaaat aaagattaaa catttttctc ctccgtatga
   104881 ttattttctt ctgtgatttt caaaaacagt tcttctaaac gattcgactt attcctcata
   104941 gaaagaactt tgattccttg tcttgtcagc tgatcgaaga ttccgttcac cccttgattt
   105001 cgttcaactt cgacagcgat tgtctgttca tcttcaaatg tacaagcgta tccttcaatc
   105061 acaggtttgg tctcatatgg cgctaaatca aagataaatg tttcaaattg cagtttggat
   105121 agaagctctt tcatactagt attctcgatc agttcacctg attggatgat cccgatgttg
   105181 cgacaaagca tttcagcttc ttctaaataa tgcgtcgtca aaatgatcgt tgtaccattt
   105241 tcgttcaatt ctcggagaaa ctcccacatc tcgcgtctca attcaatatc gactcctgct
   105301 gttggttcat ccaagatcag caaacgtggt tcatgcatca atgccctagc aatcatcagt
   105361 cttcgcttca ttcccccgga aagcatacgt gcacggacat ttctcttttc ccaaagattg
   105421 gactgcttca aatatttttc gctgcgtttc atcgcttctt tgcgagagac accgtagtag
   105481 cctgcttgat tcacgacgat ttgctggacc gtttcaaagg gattgaaatt gaactcttgc
   105541 gggactaatc caatctgttg ctttgctcgg actagatccg tatccagatc ataaccgaag
   105601 acattcactt ttccagatgt tttattgact aaagaagtaa tgattccgat cgttgtagac
   105661 ttcccagctc catttggtcc taatagcgca tagaaatctc cttctttcac ggaaagatcg
   105721 attcctcgca atgcttcgac cccacttcca taaacctttt tcaaattatt tatttcaagc
   105781 gcatttgcca tttatttcct atctccttat agacatgatt ctttattgta tcatggaata
   105841 cagcagatga aaaaacaact tggttccagc gaaaaatcag gttgctgggc tcaggaaaat
   105901 ctcctaatga aagacatcaa tcggacgaag tcagacaacc ttttcagaaa aaacaaatcg
   105961 aagataaagg attactattc atatgtgcaa caaaa
//
LOCUS       DACGMI010000003       104975 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.003, whole genome shotgun sequence.
ACCESSION   DACGMI010000003 DACGMI010000000
VERSION     DACGMI010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 104975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 104975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..104975
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.003"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(573..1325)
                     /locus_tag="IXT46_000232"
     CDS             complement(573..1325)
                     /locus_tag="IXT46_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4946181.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(1340..2587)
                     /locus_tag="IXT46_000233"
     CDS             complement(1340..2587)
                     /locus_tag="IXT46_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4946182.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(2663..2809)
                     /locus_tag="IXT46_000234"
     CDS             complement(2663..2809)
                     /locus_tag="IXT46_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HAQ4946183.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            complement(2913..3224)
                     /locus_tag="IXT46_000235"
     CDS             complement(2913..3224)
                     /locus_tag="IXT46_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAQ4946184.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(3226..3423)
                     /locus_tag="IXT46_000236"
     CDS             complement(3226..3423)
                     /locus_tag="IXT46_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAQ4946185.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(3817..5544)
                     /locus_tag="IXT46_000237"
     CDS             complement(3817..5544)
                     /locus_tag="IXT46_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4946186.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(5537..6730)
                     /locus_tag="IXT46_000238"
     CDS             complement(5537..6730)
                     /locus_tag="IXT46_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4946187.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(6917..7561)
                     /locus_tag="IXT46_000239"
     CDS             complement(6917..7561)
                     /locus_tag="IXT46_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4946188.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(7655..7789)
                     /locus_tag="IXT46_000240"
     CDS             complement(7655..7789)
                     /locus_tag="IXT46_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAQ4946189.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKKQIKR
                     "
     gene            complement(7791..9923)
                     /gene="feoB"
                     /locus_tag="IXT46_000241"
     CDS             complement(7791..9923)
                     /gene="feoB"
                     /locus_tag="IXT46_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAQ4946190.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(9920..10393)
                     /locus_tag="IXT46_000242"
     CDS             complement(9920..10393)
                     /locus_tag="IXT46_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAQ4946191.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            10794..11018
                     /gene="nrdH"
                     /locus_tag="IXT46_000243"
     CDS             10794..11018
                     /gene="nrdH"
                     /locus_tag="IXT46_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAQ4946192.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            11177..13336
                     /gene="nrdE"
                     /locus_tag="IXT46_000244"
     CDS             11177..13336
                     /gene="nrdE"
                     /locus_tag="IXT46_000244"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAQ4946193.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            13386..14351
                     /gene="nrdF"
                     /locus_tag="IXT46_000245"
     CDS             13386..14351
                     /gene="nrdF"
                     /locus_tag="IXT46_000245"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAQ4946194.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(14440..15579)
                     /locus_tag="IXT46_000246"
     CDS             complement(14440..15579)
                     /locus_tag="IXT46_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4946195.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(15888..16601)
                     /locus_tag="IXT46_000247"
     CDS             complement(15888..16601)
                     /locus_tag="IXT46_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAQ4946196.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(16855..17556)
                     /gene="nagB"
                     /locus_tag="IXT46_000248"
     CDS             complement(16855..17556)
                     /gene="nagB"
                     /locus_tag="IXT46_000248"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAQ4946197.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            17790..19322
                     /locus_tag="IXT46_000249"
     CDS             17790..19322
                     /locus_tag="IXT46_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4946198.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(19513..20715)
                     /locus_tag="IXT46_000250"
     CDS             complement(19513..20715)
                     /locus_tag="IXT46_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4946199.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(20797..21486)
                     /locus_tag="IXT46_000251"
     CDS             complement(20797..21486)
                     /locus_tag="IXT46_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAQ4946200.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(21592..21960)
                     /gene="rplL"
                     /locus_tag="IXT46_000252"
     CDS             complement(21592..21960)
                     /gene="rplL"
                     /locus_tag="IXT46_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAQ4946201.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(22013..22516)
                     /locus_tag="IXT46_000253"
     CDS             complement(22013..22516)
                     /locus_tag="IXT46_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAQ4946202.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(22926..23615)
                     /gene="rplA"
                     /locus_tag="IXT46_000254"
     CDS             complement(22926..23615)
                     /gene="rplA"
                     /locus_tag="IXT46_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAQ4946203.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(23719..24141)
                     /gene="rplK"
                     /locus_tag="IXT46_000255"
     CDS             complement(23719..24141)
                     /gene="rplK"
                     /locus_tag="IXT46_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAQ4946204.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            24484..25152
                     /gene="sdaAB"
                     /locus_tag="IXT46_000256"
     CDS             24484..25152
                     /gene="sdaAB"
                     /locus_tag="IXT46_000256"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAQ4946205.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            25165..26037
                     /gene="sdaAA"
                     /locus_tag="IXT46_000257"
     CDS             25165..26037
                     /gene="sdaAA"
                     /locus_tag="IXT46_000257"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAQ4946206.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(26128..27147)
                     /locus_tag="IXT46_000258"
     CDS             complement(26128..27147)
                     /locus_tag="IXT46_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAQ4946207.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(27320..28207)
                     /locus_tag="IXT46_000259"
     CDS             complement(27320..28207)
                     /locus_tag="IXT46_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4946208.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(28284..28829)
                     /gene="nusG"
                     /locus_tag="IXT46_000260"
     CDS             complement(28284..28829)
                     /gene="nusG"
                     /locus_tag="IXT46_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAQ4946209.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(28930..29100)
                     /gene="secE"
                     /locus_tag="IXT46_000261"
     CDS             complement(28930..29100)
                     /gene="secE"
                     /locus_tag="IXT46_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAQ4946210.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(29124..29276)
                     /gene="rpmG"
                     /locus_tag="IXT46_000262"
     CDS             complement(29124..29276)
                     /gene="rpmG"
                     /locus_tag="IXT46_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAQ4946211.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            29438..30082
                     /locus_tag="IXT46_000263"
     CDS             29438..30082
                     /locus_tag="IXT46_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4946212.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(30138..30641)
                     /locus_tag="IXT46_000264"
     CDS             complement(30138..30641)
                     /locus_tag="IXT46_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAQ4946213.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNTFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(30654..30700)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            31238..32203
                     /locus_tag="IXT46_000265"
     CDS             31238..32203
                     /locus_tag="IXT46_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAQ4946214.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(32302..33474)
                     /locus_tag="IXT46_000266"
     CDS             complement(32302..33474)
                     /locus_tag="IXT46_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4946215.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(33461..34606)
                     /locus_tag="IXT46_000267"
                     /pseudo
     CDS             complement(33461..34606)
                     /locus_tag="IXT46_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(34620..35552)
                     /locus_tag="IXT46_000268"
     CDS             complement(34620..35552)
                     /locus_tag="IXT46_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4946216.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            35669..36748
                     /locus_tag="IXT46_000269"
     CDS             35669..36748
                     /locus_tag="IXT46_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4946217.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQILEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            36745..37374
                     /locus_tag="IXT46_000270"
     CDS             36745..37374
                     /locus_tag="IXT46_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4946218.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(37484..37711)
                     /locus_tag="IXT46_000271"
     CDS             complement(37484..37711)
                     /locus_tag="IXT46_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4946219.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(37814..40402)
                     /locus_tag="IXT46_000272"
     CDS             complement(37814..40402)
                     /locus_tag="IXT46_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAQ4946220.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(40422..41081)
                     /locus_tag="IXT46_000273"
     CDS             complement(40422..41081)
                     /locus_tag="IXT46_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4946221.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(41130..41633)
                     /gene="trmL"
                     /locus_tag="IXT46_000274"
     CDS             complement(41130..41633)
                     /gene="trmL"
                     /locus_tag="IXT46_000274"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAQ4946222.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(41854..42720)
                     /locus_tag="IXT46_000275"
     CDS             complement(41854..42720)
                     /locus_tag="IXT46_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4946223.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            42829..43470
                     /locus_tag="IXT46_000276"
     CDS             42829..43470
                     /locus_tag="IXT46_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAQ4946224.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(43532..44893)
                     /gene="mgtE"
                     /locus_tag="IXT46_000277"
     CDS             complement(43532..44893)
                     /gene="mgtE"
                     /locus_tag="IXT46_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAQ4946225.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(44911..45810)
                     /locus_tag="IXT46_000278"
     CDS             complement(44911..45810)
                     /locus_tag="IXT46_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAQ4946226.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(45812..46609)
                     /locus_tag="IXT46_000279"
     CDS             complement(45812..46609)
                     /locus_tag="IXT46_000279"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAQ4946227.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLYETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(46587..47291)
                     /locus_tag="IXT46_000280"
     CDS             complement(46587..47291)
                     /locus_tag="IXT46_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAQ4946228.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            47422..47997
                     /locus_tag="IXT46_000281"
     CDS             47422..47997
                     /locus_tag="IXT46_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HAQ4946229.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            48115..48792
                     /locus_tag="IXT46_000282"
     CDS             48115..48792
                     /locus_tag="IXT46_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAQ4946230.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(48871..50679)
                     /gene="pepF"
                     /locus_tag="IXT46_000283"
     CDS             complement(48871..50679)
                     /gene="pepF"
                     /locus_tag="IXT46_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAQ4946231.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTSVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(50855..51853)
                     /locus_tag="IXT46_000284"
     CDS             complement(50855..51853)
                     /locus_tag="IXT46_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAQ4946232.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(52079..52732)
                     /locus_tag="IXT46_000285"
     CDS             complement(52079..52732)
                     /locus_tag="IXT46_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAQ4946233.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(53064..53462)
                     /gene="spxA"
                     /locus_tag="IXT46_000286"
     CDS             complement(53064..53462)
                     /gene="spxA"
                     /locus_tag="IXT46_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAQ4946234.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            54227..54934
                     /locus_tag="IXT46_000287"
     CDS             54227..54934
                     /locus_tag="IXT46_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAQ4946235.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            complement(55080..58274)
                     /locus_tag="IXT46_000288"
     CDS             complement(55080..58274)
                     /locus_tag="IXT46_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4946236.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(58293..61421)
                     /locus_tag="IXT46_000289"
     CDS             complement(58293..61421)
                     /locus_tag="IXT46_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAQ4946237.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            complement(61428..62549)
                     /locus_tag="IXT46_000290"
     CDS             complement(61428..62549)
                     /locus_tag="IXT46_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAQ4946238.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            complement(62741..63364)
                     /locus_tag="IXT46_000291"
     CDS             complement(62741..63364)
                     /locus_tag="IXT46_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAQ4946239.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            63493..64227
                     /locus_tag="IXT46_000292"
     CDS             63493..64227
                     /locus_tag="IXT46_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAQ4946240.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            64217..64501
                     /locus_tag="IXT46_000293"
     CDS             64217..64501
                     /locus_tag="IXT46_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAQ4946241.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(64576..66459)
                     /locus_tag="IXT46_000294"
     CDS             complement(64576..66459)
                     /locus_tag="IXT46_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAQ4946242.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(66725..67600)
                     /locus_tag="IXT46_000295"
     CDS             complement(66725..67600)
                     /locus_tag="IXT46_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4946243.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            complement(67709..69478)
                     /gene="aspS"
                     /locus_tag="IXT46_000296"
     CDS             complement(67709..69478)
                     /gene="aspS"
                     /locus_tag="IXT46_000296"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAQ4946244.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            complement(69493..70785)
                     /locus_tag="IXT46_000297"
     CDS             complement(69493..70785)
                     /locus_tag="IXT46_000297"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAQ4946245.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            71179..72126
                     /locus_tag="IXT46_000298"
     CDS             71179..72126
                     /locus_tag="IXT46_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAQ4946246.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            complement(72215..73474)
                     /locus_tag="IXT46_000299"
     CDS             complement(72215..73474)
                     /locus_tag="IXT46_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAQ4946247.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(73645..74091)
                     /locus_tag="IXT46_000300"
     CDS             complement(73645..74091)
                     /locus_tag="IXT46_000300"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAQ4946248.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            complement(74102..76315)
                     /locus_tag="IXT46_000301"
     CDS             complement(74102..76315)
                     /locus_tag="IXT46_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAQ4946249.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            complement(76548..77312)
                     /locus_tag="IXT46_000302"
     CDS             complement(76548..77312)
                     /locus_tag="IXT46_000302"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAQ4946250.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            complement(77313..78260)
                     /gene="prmA"
                     /locus_tag="IXT46_000303"
     CDS             complement(77313..78260)
                     /gene="prmA"
                     /locus_tag="IXT46_000303"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAQ4946251.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            complement(78273..78761)
                     /locus_tag="IXT46_000304"
     CDS             complement(78273..78761)
                     /locus_tag="IXT46_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAQ4946252.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            complement(78727..79398)
                     /locus_tag="IXT46_000305"
     CDS             complement(78727..79398)
                     /locus_tag="IXT46_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAQ4946253.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            79536..80822
                     /locus_tag="IXT46_000306"
     CDS             79536..80822
                     /locus_tag="IXT46_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAQ4946254.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            80894..81088
                     /gene="ssrS"
                     /locus_tag="IXT46_000307"
     ncRNA           80894..81088
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="IXT46_000307"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            81166..81450
                     /locus_tag="IXT46_000308"
     CDS             81166..81450
                     /locus_tag="IXT46_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946255.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            81523..82002
                     /locus_tag="IXT46_000309"
     CDS             81523..82002
                     /locus_tag="IXT46_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4946256.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            82225..82368
                     /locus_tag="IXT46_000310"
     CDS             82225..82368
                     /locus_tag="IXT46_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAQ4946257.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            82946..84529
                     /locus_tag="IXT46_000311"
     CDS             82946..84529
                     /locus_tag="IXT46_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4946258.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(84966..86150)
                     /locus_tag="IXT46_000312"
     CDS             complement(84966..86150)
                     /locus_tag="IXT46_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAQ4946259.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(86175..87182)
                     /locus_tag="IXT46_000313"
     CDS             complement(86175..87182)
                     /locus_tag="IXT46_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4946260.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            complement(87354..87713)
                     /locus_tag="IXT46_000314"
     CDS             complement(87354..87713)
                     /locus_tag="IXT46_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946261.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            complement(87685..88056)
                     /locus_tag="IXT46_000315"
     CDS             complement(87685..88056)
                     /locus_tag="IXT46_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAQ4946262.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            complement(88073..88375)
                     /locus_tag="IXT46_000316"
     CDS             complement(88073..88375)
                     /locus_tag="IXT46_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946263.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            complement(88392..88862)
                     /locus_tag="IXT46_000317"
     CDS             complement(88392..88862)
                     /locus_tag="IXT46_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAQ4946264.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            complement(88837..89115)
                     /locus_tag="IXT46_000318"
     CDS             complement(88837..89115)
                     /locus_tag="IXT46_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAQ4946265.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            complement(89112..90161)
                     /locus_tag="IXT46_000319"
     CDS             complement(89112..90161)
                     /locus_tag="IXT46_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAQ4946266.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            complement(90118..91047)
                     /gene="cpaF"
                     /locus_tag="IXT46_000320"
     CDS             complement(90118..91047)
                     /gene="cpaF"
                     /locus_tag="IXT46_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAQ4946267.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            91179..92933
                     /gene="ade"
                     /locus_tag="IXT46_000321"
     CDS             91179..92933
                     /gene="ade"
                     /locus_tag="IXT46_000321"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAQ4946268.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            complement(93031..93693)
                     /gene="trmB"
                     /locus_tag="IXT46_000322"
     CDS             complement(93031..93693)
                     /gene="trmB"
                     /locus_tag="IXT46_000322"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAQ4946269.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(93763..94542)
                     /locus_tag="IXT46_000323"
     CDS             complement(93763..94542)
                     /locus_tag="IXT46_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAQ4946270.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            complement(94749..95960)
                     /locus_tag="IXT46_000324"
     CDS             complement(94749..95960)
                     /locus_tag="IXT46_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4946271.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            complement(95953..96690)
                     /locus_tag="IXT46_000325"
     CDS             complement(95953..96690)
                     /locus_tag="IXT46_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4946272.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            96828..97262
                     /locus_tag="IXT46_000326"
     CDS             96828..97262
                     /locus_tag="IXT46_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAQ4946273.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            97255..97599
                     /locus_tag="IXT46_000327"
     CDS             97255..97599
                     /locus_tag="IXT46_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAQ4946274.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            97779..98789
                     /locus_tag="IXT46_000328"
     CDS             97779..98789
                     /locus_tag="IXT46_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4946275.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(98858..99802)
                     /locus_tag="IXT46_000329"
     CDS             complement(98858..99802)
                     /locus_tag="IXT46_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4946276.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(99786..102506)
                     /locus_tag="IXT46_000330"
     CDS             complement(99786..102506)
                     /locus_tag="IXT46_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4946277.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            complement(102503..103723)
                     /locus_tag="IXT46_000331"
     CDS             complement(102503..103723)
                     /locus_tag="IXT46_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAQ4946278.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            complement(104004..104849)
                     /locus_tag="IXT46_000332"
     CDS             complement(104004..104849)
                     /locus_tag="IXT46_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4946279.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
BASE COUNT        31115 a        21745 c        18183 g        33932 t
ORIGIN      
        1 atattaaatt tttatctttt attaaagtca gataaaaatt ctttggaaat gtaatggtag
       61 agatattttt acaaaaggac ttgcagcgct gtagttggtg ctgcaggagg acctatttcg
      121 gccgttacag gaggtattgg taatgtactt gtcggatgtg cattaaagcc tgttcctgca
      181 agttaaattt ataaaaacag gaaagtaatt atctcaaatc ctatcaagta caatcatagg
      241 attgcacttg acaggacaaa ttttttaact aaaaaatgaa aaacactttc taaaaattag
      301 tagaatttgc caaatctttc gcatcttcca ccatacattt aattttaatt cccctttatg
      361 gtacttaata aaaacaagaa aagaactatt catttggccc ttttttggtt ccagaccata
      421 gaaatattcc tccagtaact aatattgctg ttatgcacgt aactaataac agctataaaa
      481 attggtacaa ctttaatagg attcagaaaa atttgcacta gtgaaggaat ctattttatt
      541 agaaaaatgc aatctcccta aagaaaaaac cactaaacag tgctttcttt caacttctcc
      601 ttaatttttt gtgctttccc taaagtaaag tttctggcca actctgaatc aaaatatagt
      661 gaacgttttt taaaatctat ttctttaacg ttaaagatat ttactaaaca cgctcgacta
      721 attcttgtta acataggata tttcttttca agctcactaa ttcttccata aaattcgtac
      781 tgcccatctt tagtacacaa tgataatcta tgtggtaatt ttgaagcttc tacaaaataa
      841 atgtcattta tatcaaaagt aaatgtttga gaacctatgg aaaaaacaaa tgcttgattc
      901 gtaacctgtt ttgttgcatc tatcctttct tgcgctaata acaataactc aacaatctcg
      961 tttcgatact catctagtgt ttgatctttt gttacaaatc ctaacgtttc aactcttctt
     1021 tttattgtta cgggtaacat ctcatcatga gtagttgtaa aaatgatttt tgcttgaaca
     1081 tcatattttc tgattacttc tgctaattct ataccgttaa cttcatgatt taaatcaata
     1141 tctaagaaat atattccttg ctttggtcgg aattgtttga ggtatttttt aacttctaac
     1201 ggactttgtg ttttcaatac tatcttaaat actttatcgt gaaaaagaat gaaattatca
     1261 ataattcgtt ctaactgatt taattgtata atttgatctt cacataatat tattggataa
     1321 ctcataaatc ctccttccct caaaacaaca aaataacttg agtagtaaat tgatacggat
     1381 cgttttgata gttcacaaac atattgggat tctttttatt gatttcctct atactagata
     1441 aacctaaccc ttgatgtccc ttttttgttg ttattccttt tttcattaga gtatctatag
     1501 agagtagtat ctctctacaa ctattcgata tcgaaatttc tatctgttta tcatctcggt
     1561 aaatagctag agacagttct ctatcttgac tctctataga tgcttcaatt gcattatcga
     1621 gaataattcc aagcacccta atacagtcaa atattggaac aggaacttca ataatagtac
     1681 ttggacattc gaatttacaa caaatcttat tgttatttgc ttggtatagc ttcgctatca
     1741 acaaactttt caaatattca ttttttatat tttttaaata acgatattca aacttattgg
     1801 ttagataaga attagaatag atctctaatt cttttatttc tttttccaat atcgaatcat
     1861 ggttttgatt agcgatttct tttaaactca gcaataaatt tttatagtca tgtctaaatc
     1921 tggcaaattt ttcttgatct ttttccagtg aatcagtata tttttttaga taaaccaatt
     1981 cttttctttt caattgctgt tcatattgtt ctcgttgcct aatagttatt ctaataaata
     2041 aaaatagaac aacaaacatt tgaatgatta aaaatattaa gacaccaaac acaaaatgat
     2101 caaatacttg atattgatga gcaacataag aaacaaataa accaattgta agtaaataaa
     2161 tcatgaatat agcagtaagt ttagaactgg actgttcaac aatcctattt atagctaatt
     2221 ttctatataa ccaaataaac atcagcaaaa acaaagaatc aagcattatc tggaatacta
     2281 cataaccata cccttttatc ccttcaaatg aaaacatata cgtcataacc atggaagtaa
     2341 taatagatct gaaatcatca ataagcatac ataatagtaa tttatttaaa agcactatat
     2401 tagttttctt cttttccttt aatataaaat aacttccgat tataggtata gctgcggaaa
     2461 catcagtaaa taattcaaca aaaaaagtga gtggtatcaa taaacataca aaaagatatt
     2521 ttcttttgtt aagatcagta ttagtcatat aaaataagag aaaaaagaaa aagtttccca
     2581 cgaacattct taatagataa gcttttgtat cgatagtaat caagagatcc cctcctgatt
     2641 ttaggatatc ataaaaaaaa ttttagttac actttttaaa taatgaaaaa acacattcca
     2701 ctaaatttga tgccggtttt ccttgaggtt ttgttccagc acctccttta atttttttaa
     2761 gctcttgatc tgaacattgt ttagcattta gtctattttt ttcttccatt acgattcccc
     2821 ctacaaacta taaatacttt tatgtcactg attcaatata cctatttttc taatcaaaaa
     2881 attttgagac atatttaata ttataagtat cattaaaatt gagatttatc tccataatct
     2941 gctcgatata aaccatttat tccagcagtt cttccaattt cactcaaatt tcttattaat
     3001 tcctcttgat attcagtgaa tcttatttta ttagtataag cagtaaaata tagataattc
     3061 accaatctat ttattaaagg actgggatct aattcatatt tttgtttttc taattttaaa
     3121 tatacctttt gtaaaacctc aagaatatca gaatatttag gatctttact tatagatata
     3181 tcattatata attcatgaac aatttgctta gcattttttt tcattttagc acttccctgg
     3241 aattgctcca cctaaaaaac cacctataga cattcctgca atacaagtag ttgccttggc
     3301 ccaatcgacc gtacatttat ttttagtgca atacactcca tttccataat attttccact
     3361 atgagtggta cccccataga taagttgtgt ctctttaata gacaaaattt ttaaatgttt
     3421 cataatctaa tcacccctaa attaatgttt ttagactatt attctaacat tcattaaatt
     3481 tcaaaaaaca attccttctt gaaacgtagc aaaataattc ctgaataaga atttaatcac
     3541 ttttaagtat ataaactatg tatattcttt aatatttttt gagaatgcac ttcgtacata
     3601 ataaacttta atcacattag tctttcatac ctacgatcga tctctttgac tcgcacccat
     3661 aaattcataa tagtttgtcg gcgtctttgg acgtttcgaa gatgagctac gcattctctt
     3721 tttttataga caaaaaagat agagacgaac atggagcttc caaatttgga tatttgatcc
     3781 aattttggaa gctccattta tttcgtgtct gtctttttat tttttccagc tttcgactaa
     3841 ttcttggttc tctttgatcc agtcttttgc tgcttgctgt ggatcttttc cattgttgat
     3901 ttccaacata actttttcca tatctttttc tgaccaatgg aaattgtcta atactttgta
     3961 agcttctggc tggtcttctt tcaatccttt tcgaaccatc gtatggatct gctcttcgct
     4021 tcccattccg ttttcaggat cttctaagta tttcagatca tatttggcaa acatccaatg
     4081 aggtgtccat cctgtaacta caattggttc gtgttttttg atcgcttgac ctagtgcaac
     4141 ggtcattgct cctgaagaag atgtctctac tttccagtct ttcaagttgt catatttttg
     4201 gatcgtgttt tcagcagccg taactacacc agctcctggc tcgattccta tgattttctt
     4261 acctgcctga tcggttaact catcgatcga atttacatcc atgtaggctg gcactgctaa
     4321 accaactttt gctcctgtca aattggcacc taggtcttcg acttgatctt tatattgtgc
     4381 atattgtgaa ccatgagttt taggtagcca agctgaaacc atggcatctg actcgccatt
     4441 tgaaacagat ttccacatga ttgaattatc taatggcgtc atcgttacat catagcccat
     4501 ttgtttcaat acttcaccga ctacatttgt tgaagcaact tctgtatccc attcaacata
     4561 agataagttg atacgttttg tttctttggc agatgaaaaa ctccctatac caatcgcacc
     4621 taagatcact actactacag caccaatgat cagtccttga cgttttttac ttttctgtgt
     4681 tgttgctcct gcagcttttt tattgtttgg ctggttcaaa tgctgtgtaa aacggtcaat
     4741 gatgattgct aagataacta atgcaacccc gttgacaaat ccattcccga cttgtgctct
     4801 ttgcaatgct gataatacgc cgcgtcctaa gccgggtgca ccgatcatag aggcaataac
     4861 gaccattgaa agtgacagca ttgttgtttg attgatccct gccatgatcg tacttttagc
     4921 taaaggcaat tctagtttga atagtttttg acgacttgtg ctcccgaatg aatcagaagc
     4981 ttctactaat tctttaggaa cttgtcgaat ccctaaattc gtaaaacgaa cggttggtgg
     5041 cagagcaaag atgactgagg caaatacccc tggaaccatc ccgataccga aaaatgcaac
     5101 tgctggaatc aaataaacga atcctggcat tgtctgcata aagtcaagga tcggtttgat
     5161 aatactttgg gctttactgc tttttgccat caagatccct aatggtaccc caatgatgat
     5221 cgagatcaca ctagataaaa gaacaagtgt gacagtattc atcaaatcat tccatagacc
     5281 ttggttataa ataaaccata gaccgattaa tgtgaacaac gtaagtcctg gacgtttctt
     5341 agaaataaag aaagctgcta ccgtcaataa caagataaac aaaggagctg gaatcactaa
     5401 cagtaaattt gtaatccccg acatcactgc ctgtccaatc gtttgtaaaa atgaaaatag
     5461 gccagaaaaa gttgtcgtaa accattctgt gatattttct acccagtttg ccactggtaa
     5521 ttgatagttc aatagattat tcatgttcac tcacctcgct tgtttctgct aatgcttcaa
     5581 tcacactacc tcggatgacg acacctttta attttccatc ctctacaact gcaagtggag
     5641 tcggtgagtc ataaataata ttgaaaatat cacttaccac catgtctttc ccaatcaccg
     5701 tcacattttc atctaggaag tcgatcaatg gacgtttttg cttcctagct tctaacgctt
     5761 gatctgcagt gatgatccct ttcaggtgtc tctttctgtc aacagccatc agcatgctga
     5821 cttcttcatt acgcatcctt gtcaatgcaa cgtttggtcc atcagattcg atattcgtcg
     5881 tcaatgcagg taccatgatg ttttgagccg taagcacttt ggaacgatcg acttcttcca
     5941 caaattcacg tacataatca tttgctggat tggtcaatat ttcttcacct gttccgatct
     6001 gcatgatttc gccgtctttc atcaaggcga ttctgtcccc aatccgtaaa gcttcattca
     6061 aatcatgggt aatgaaaata atcgtttttt gaacattggc ttgcaggtcc agtaattcgt
     6121 cttgcatttc tcgccggatc agcggatcaa gagccgagaa cgcttcgtcc atcagcaaga
     6181 tctcaggatc atttgctaaa gctctggcta ggccaacccg ttgttgcatc ccaccagata
     6241 actgactagg atattggtct ttaaatgaaa gcaaactaga attttctaat gctttttctg
     6301 ctttttcttg tcgttcttct ttaggtacac cacggacttc taacccgtat tctgtatttt
     6361 ccaagatcgt tcgatgtgga aacagaccga agttttggaa aaccatattg attttatgac
     6421 gacggacttc tcgcaattct tctttgctta acttcgatac atcttctcca tcaatataga
     6481 tactgcccga agttggctca atcagacgat tcaatagacg gatcaatgtg gatttcccac
     6541 tcccggaaag ccccatgatc acgaagattt ctccttcttt tacgtcaaaa ttcacgtcat
     6601 acacaccaac cgttgcaccg gttttcttta aaatctccgt tttcggctgg tgatcattca
     6661 tcatatctaa agcggcttgt gtctttttac caaatatctt tgttaaatgt tttacttcta
     6721 cttttaccaa acaaattctc cttttttatg taaattcatt tttctttctg aaaaaagtga
     6781 ccacactatg ttaacatcat gtagtcactt tgtcaaaaat gaaagaaatt tgcttgtcca
     6841 aactgaaaaa aacttggcta aatctttgta aataaaaggt ttagccaagt taatattttt
     6901 ttaatatttc acacaatcat tctgcaagct gatgctccgg gtaaaaaaag tttgtcatac
     6961 gctgtagtgt atattcattt ccaataaaat gaacgatgtc ccctgccgta aatttagcat
     7021 aggggccagg tgaaacaagc agttcttcat tatgagaaat tgcgataact gtggcgccag
     7081 tcgcctgcca gatattcaac tcgctaattg aacggtccag atgcattgct ttttctgata
     7141 aagataattc aaacggaagt aaaggattca tcttatgtat tcgcttcgtt tgattgacca
     7201 gctgatccaa taattgagaa aaatgattca gctcatcttg ttgcttctcc acacttgcca
     7261 tgatttctgc ttttgtatct tggatggatt gtacatcttg atattgcaat aggaaatctt
     7321 ttgctttttc cttcgaagca acaaatgccc cacttccatg ccgtacttcc atgattccaa
     7381 gatctaccag cacattgata gccttgcggg tagtctcagg agaagcattg tacgtactgg
     7441 caagtgttga gcgggcatgg atcttctcac ccactttata tcggttttca acgatacgtt
     7501 cggctaaatc aacagcaatc tgctggtagc gcgggcggac gatttttttc tttccagaca
     7561 ttttctttcc tctttctttt tttactttcc ctcatcttac tatgctctag caaaataagc
     7621 aaaaaagggg agaatagcct cttgcaacga ctgatcatcg cttgatctgt ttctttttta
     7681 ctgggcaagc tgtttgacag tcatcacaat tcttaccgga ttttaaacga gtatagacaa
     7741 ttgcgcctgc acttccaaag attaacacac ttaataagaa tgtcgccatc ctattcctct
     7801 ccttctaatg acaatatagt ataaaactgg ttcttggatt ttggctgacg gaacaaaaca
     7861 taaacgagtc ctatcatcag taaaatagca agatacgtcc ctaacgctac ctgtccaccc
     7921 tccaataagt gtcccaactg ataaatcaca aaactaacta aataagctaa accgcattga
     7981 tagcctatgg cgatccaagt ccatttcttg gcattcattt cccgatggat agccccaatt
     8041 gccgcaaaac aaggcgcaca aagtaaattg aaggctaaca atgaataagc tgctgcggga
     8101 gtatatgtgt gttgtagcac ttgccagatt tctctgccat tttcggatac ttccgcatga
     8161 ccaaacaaaa taccaaatgt gccaataata ttttctttag cgaccaatcc tgtaatcgct
     8221 gcgactgttc cttgccagtt tccccaacca agcggctgaa aaacaactgc caggattcgc
     8281 ccgaaaaagg ctaagatact ttggtcttca gaaacaggtt gagcataaaa attataagaa
     8341 gagctgaacc agatcacgat actagaaaca aagataatcg ttcctgcttt tttaacaaaa
     8401 gacttgctgc ggtcataggt ttgtcttagg accgctgacc attgaggaaa atgatatgcg
     8461 ggcaattcca tgataaaagg agctgtatct ccagcaaaca aacgtgtttt tttcaagctg
     8521 attccagaga aaataattgc agtcatacca agaaaatagg cagaaggagc tacccaagat
     8581 tgatgaggaa aaaaggcccc tgctactaag gcaataatcg gcaactttgc agaacaaggc
     8641 atgaaggttg tgaccatgat cgtcaaacga cgatcttgct cgttttcaat cgtgcgactg
     8701 gccatgacgc ctggcactcc acatcctgta gcaatcagca taggaatgaa ggattttcct
     8761 gaaagaccga atttcctgaa aagtcgatcc atgacaaaag cgatcctcgc catatatccg
     8821 cagtcttcca gaaagctcaa gcataaaaac aatataatca attgcggtag aaatcctaac
     8881 actgctccca cgcctgcgat gatgccgttc aagatcagct cctgcatcca tcccgctact
     8941 tgccattcag ctaacaatct gccaacatgt tctggtaacc atgtaccaaa caatgtgtca
     9001 ttgatccaat ctgtccccat tgttcctact gtttgaatag ccagataata gatcagccac
     9061 atcacaaatg cgaagatcgg caaggctaac caacgattcg ttgcaatctg atcgattttg
     9121 tcactcatcg ataattggaa agaatcattt gacacaacac agagtgtaca tagttgggta
     9181 ataaattcat aacgttcatt gaccagaatc gtctcactat cgtcgtccaa tagtttctct
     9241 gttaactgga tcagttgctc gatctctttt tgctgagaaa ctgctatctc gtaatcctct
     9301 cttaccttct gatctcgttc aaaatatttc attgcatacc agcgtttctt gccgctttgt
     9361 tctcctagta catcttcaat ttcatgtaaa gctgcttcta aacgtggatc atatgtacag
     9421 ggaacaggaa tagaaggccg cttttttgca gactcctgaa tcttttcgat tagtttttcg
     9481 attccttgct ttttcaatac gctgattggt aaaactggta caccaagacc ataggaaagc
     9541 ttttctagat tgattttttt tccttctttt ttgatgacat ccatcatatt cagaccaatg
     9601 atcataggaa tgtctaaatc caataactgc gtagttaaat aaagatttcg ttctaaattg
     9661 gtagcatcaa taatgttgat gatcagttca ggctgttcct gaaccaaata atctcttgca
     9721 atcacttctt ctggtgtata aggagacaaa gaatagatgc cgggtaggtc ctgaatatga
     9781 atgttcggat tttttttcaa cgatccttct tttttttcta ctgttacgcc cggccaattc
     9841 cctacatatt gattcgaacc agtcaagaga ttgaacaagc tagttttccc gctgtttgga
     9901 tttccgacta acgcgatatt cattcttttt cctccctttg tatcaagatt agttcggcct
     9961 ctgactttcg taacgtcagt tcataccctc gcactgtcag ttcgattgga tctcccagag
    10021 gggctagttt tcggataact atttttacat ttcgcgtcaa tcccatatcc attaaccgtc
    10081 gcttcactgc gccttgtccg tggattgcta cgacgatccc agtctctcct gcttttaatt
    10141 gatcaagaga agtccagctt tcagaggaag cagtcttttt attgacaaag atttgaccta
    10201 gtatttcccg acttactgcc actcgatgac tttttaccag taaaatggca ttgttgcctg
    10261 ataaattgac gacgacgatt ttacttccgg caacgatccc gatattttgc aaatggcgtt
    10321 ttgttttttc ttctgtttcg attcgttcga cttgataaac gaaattctgc tttgcctgcg
    10381 ctaaggtctg catattgatt cctctcttgt gaaataaatc atgtattaaa atcattcatt
    10441 atatgttcta attttcttac gtgttacgca aataaatgag aatcattctc acatagaata
    10501 ctctcggtaa ttgagaatgt caattatact tgtgatatta tgagcgaatc tttagtattg
    10561 atagataaaa atgagaaaaa aatatttctt catagttttc cacaattttt tctctattaa
    10621 atttgctatt ttcccacacg atacttgttt tcagctcttt tttcaaaaac acaaaactta
    10681 gtattccaca gtttccacaa cacaatatgt agtgtttgtt gtttgacttt tttactaaga
    10741 gttttatact atctattata gataataaga atgtgttaga ggaggcactc accatgaacg
    10801 taaaaatctt ttctaaaaat aattgtatgc aatgtaagat ggtcaaacgg tttttaacag
    10861 aaaatcaaat tgcttttgaa gaagtcaata tcgatgaaca gcctgaagca gtagactggt
    10921 tgaaagcaca aggattccaa agtgttcctg tcattacttc tgatgcagaa acagttatcg
    10981 gattccgtcc tgatcagttg cgtaaacttg ccagctaaca tgactaaaag aatcaaaacg
    11041 tgatacatgg atttgaaggg cttgagacag caccagtttt tgtcgcaaac ttccaaatcc
    11101 ttttttaaag cttaaaaaca atgcaatgat ttgcaatcaa gcatcatcaa atacgaaatg
    11161 aaggttgggc gtacgtatga gtcttaaaaa tttacaagat gtcagttatt tcaagctgaa
    11221 taatgaaatc aatcggccag tcaatggtca aatccctttg aataaggata aagaagcttt
    11281 agttgccttt tttgaggaaa atgtcaaacc aaatacgatg acttttccat ctattatgga
    11341 aaaaatcaat tacttgatcg atcaagaata tatagaagca gaattcattc aattgtattc
    11401 accatcattt attgaaaagc tatatcaatt tttggacgag caacattttt ctttcaaatc
    11461 ttttatggct gcttacaaat tttattctca atatgcgttg aaaaccaacg acggttccgc
    11521 ttatctggaa acttatgaag atcgagtagc cttcaatgcg ctttactttg cgaacgggga
    11581 tgaagaatta gcacttgctc ttgcagacga aatgatccat caacgatatc agccagctac
    11641 accttctttc ttgaatgctg gacgtaaacg tcggggcgaa ttggtgtctt gtttcttgac
    11701 tcaagtcact gacgatatga actctatcgg gcgctcaatc aactctgctt tgcaattgtc
    11761 ccgtattggt ggcggcgtag ggattacttt atcaaatctt cgtgaagccg gcgctcctat
    11821 caaaggatat gagggtgctg caagtggtgt cgttccagtc atgaaattat tcgaagatag
    11881 tttcagctat tctaatcaat taggtcagcg tcaaggagct ggcgtggttt atttgaacgt
    11941 tttccatcca gacattattg ctttcctttc agcaaaaaaa gaaaatgcag atgaaaagat
    12001 tcgcgtaaaa actctttctc ttggcgtgat cgtacctgat aaattttatg aattgacacg
    12061 taaaaacgaa gatatgtatt tatttagtcc atatagtgtc gaaaaagaat atggtgtccc
    12121 attctcttat gtaaatatta cagctgagta tgatcatcta gttgcaaatc caaacattcg
    12181 caaacaaaaa atcaaagcgc gtgatcttga aaatgaaatc tcaaaattac aacaagaatc
    12241 tggctatcct tacgtaatca atattgatac agcgaaccgc gagaatccaa tcgatggcaa
    12301 gatcatcatg agtaatttat gttcagagat tttacaagtt caaacgcctt ctgtgattaa
    12361 cggcaaacag gaatatgaag tattaggaac agatatctca tgtaacttag gctcgacaaa
    12421 tatcgtgaat ttgatgcaaa gccctaactt tggtcaatct gtgcgtacga tgactcgtgc
    12481 attgacattt attacagatg catctgatat cgatgtcgta ccaccgatcc aaaacggaaa
    12541 taagctgaat catacgattg gattaggtgc catgggctta cacacttatc ttgcaaaaga
    12601 acaaatggaa tatggctcag aggattcatt agactttaca aatatttact tcatgctgtt
    12661 gaattattgg acacttgttg aaagcaacaa tatcgctcgt gaaagaaaac aagttttcca
    12721 taattttgaa aaatcagctt atgctgacgg cacttatttc gaaaaatacg taactggaga
    12781 attccagcca aaatcagaaa aagtcaaagc attgtttgaa ggcattttta tcccaactgc
    12841 tgaagattgg aatgctttga aacaagcagt aatgaaagat ggactgtatc atcaaaatcg
    12901 cttggcagta gcaccaaatg gctcaatttc atatatcaac gatacgagtg caagtattca
    12961 tcctatcact cgcatgatcg aagaacgcca agagaagaaa atcggtaaaa tttattaccc
    13021 agcgccttat ctatccaatg agacgattcc gtattacact tctgcttatg atatggacat
    13081 gcgtaaagta atcgatgttt atgcaacggc acaacaacac gtcgatcaag gcatgagttt
    13141 gactttattc atgcgttctg aaatcccaga aggcatttat gaatggaaga caacaacgaa
    13201 gcaaacgaca cgtgatttga atattttaag acattacgct ttccacaaag gaatcaaatc
    13261 catttattac gtacgtacct ttactgatga tgcagaagaa atcggaagca atcaatgtga
    13321 aagctgcgtg atctaatatc atagatagat tcgcttattc atattttaat taaaggagca
    13381 ttctcatgtc agaaacatat tatgaagcaa taaactggaa tgaaattgaa gatatcattg
    13441 ataaatccac ttgggagaag ctgacagagc aattttggct agatacacgt atcccacttt
    13501 caaatgacct agatgattgg cgtacattgt ctcaattgga aaaagataca gtaggacatg
    13561 tatttggcgg tttgacactg ctagatactg tccaatctga aagtggcatg gatcagttgc
    13621 gtaaagatgt ccgcactccc catgaagaag ccgttttgaa caatattcaa ttcatggaat
    13681 ccgttcatgc caaaagttat tcttctattt ttagtacact gaatacgaaa aaagaaatcg
    13741 aagaaatttt tgactggaca aatacgaatc cttatctgca aaaaaaagct gagcgtatca
    13801 atgaaatcta caaacacggt acaccgctag aaaagaaaat tgccagcgtc tttttagaaa
    13861 cattcttgtt ctattcaggt ttttatactc ctctttatta tttaggaaac aacaaattgg
    13921 ctaacgtagc agagatcatc aaactaatca tccgagatga atctgtacat ggaacctaca
    13981 tcggttacaa attccaatta ggattcaacg agttacctga agcagaacaa gaaacgttaa
    14041 aagactggat gtacaatctt ctttatgagc tttacgaaaa cgaagaacgt tatacagaag
    14101 aattatacga tccaatcggc tggacagaag aagtcaagac attcctacgc tataatgcca
    14161 acaaagcatt gatgaaccta gggatggatc cactctttcc agatactgcc aatgatgtca
    14221 acccaatcgt aatgaacggg atttcaacag gcacaagcaa ccatgacttc ttctcacaag
    14281 tcggaaacgg ctatttgtta ggtcatgtag aagcgatgaa agacgacgat tatttgattg
    14341 gattggaata aggatttatt ttaattcaaa aatttttcga aaaataaaaa gagtttagcg
    14401 tacagatatt ttaaatgtac actgaactct tttttatgct tattcacttg tttcttccag
    14461 cacttttgga ctgtctaact tttccgaaac atgttccatt cttctcaata aatagatttt
    14521 ccggatattt aatattatcg tcttaatcac tgcatagaca ggtatgcaaa tcagcatgcc
    14581 taatattcct gcgacacttc ctgctccaat caataccaag atgatcgtca aaggatggat
    14641 attcattgat ttcccaaata acaacggctt gatcaaattt ccatctaatt gttggatcac
    14701 taaaatcgac aacgccatat acaaagcttg aaatggagag ataaacaaac cgacaatgat
    14761 tgctggtacc gctccaataa aagggccgac atacgggata atattcgtga ttccgcaaat
    14821 gaccgcaagc aacaagctat aaggctgatc gaatattctc attgccaaaa agctcattac
    14881 accaataatc aaagcatcta agatcgtact gctgatatag gcagataatg tttcgtttaa
    14941 ttcttttacc gtttggcgta actctttacg aatcgctttc ggaaagaagt gagacaacgc
    15001 atcaataaat ttgtgcccat ccttgaacat aaatagcaaa ataaatggaa cggtaaataa
    15061 caaaataaaa aattgcatca taaatgaaat gatttttgag acacttgcag ataaactgac
    15121 taatatgata ttgaacaaat tactaagaga taaatttgct gatgctaatt gttcttccaa
    15181 attgaaattt ttaaactctt cccgctgcgc caattcattt aaccatttgc ttgtttcatc
    15241 tgcatacatt ggcaagctct gggtcaattg aattgtctgt tccattaact gaggcactac
    15301 attcatgaca gttaaaacaa ctaaaatgat tacgaccaaa aacgtcaata aaaaaccgaa
    15361 cactctcggg atccgatgct tttcgagaaa aacaacgatt ggatcgaaca tataatagat
    15421 aaaaccagca acaagcaatg gtaaaaaaac tgccgaaagc attttcaata ttggactaaa
    15481 aatattcggc atttgtaaaa taaagtacac gccgatgatc gtgagtacta gctccactgt
    15541 ccagaaaaat aattttgatt gtttaaaacg tgattgcata catctcctcc aaggtccttt
    15601 gatacttcta ttctatcatt taacaaagag ttacgcgctg agattttcat ttgcttaaaa
    15661 aaaacaaaaa aaataaacat attttaatga gtagacgagt acttaaacaa aaacacggtt
    15721 tggagtagtg acaaaaatta tactgcagtc cctttttcca aataaacggt gttcaaaagc
    15781 ttgcatcttc gtaataagcc cagccaaacg aaaaatataa ggaactattt ttatttggct
    15841 gggcttatta cttgatgtag gacatctatt ttacaacctc agatcattta ttgcgcaata
    15901 ctgactaaat gcaactttgt gatatttttg tgtacggaca actcctcgat cacatcggca
    15961 taagtgagcc cttttggaag atcaatcgta tagatatttt tgtacactcg gtagtcatca
    16021 acgaatttta cgtcaaaatt cacatcttcg attacgatat ttttctcttc aaaataatcg
    16081 gtaagaaaat ctttggtttc ttttctatgg ataaattgga tttctaactt tttagtcgta
    16141 ggtacatgga tcacgcgttt cactactgtg agtgcaatag caatcccgat aaaactgatg
    16201 atcgcaatgg aatagtaacc catgccgatg gcgatcccta atccagcaat tgcccataaa
    16261 gaagcggcag tcgtaagtcc cgtcaccgat tgtttcgtga cgatgatcgt tcccgcgcct
    16321 aagaaaccga caccactcac cacttgagca atcagccttg cttcatctga acgaatcgtt
    16381 ccagcaagct gtggatactc taaagcatct cttaatgcac cactagcgat ctcaacttgg
    16441 atcaatgcaa tgatacatgc tcccatacaa actaaaatat gcgtacgcat acctgctgga
    16501 cgatttttat attgtcgttc aaaaccgatt gctccgccaa atagcatagc gatccctaaa
    16561 cgtaaaataa tctctggaat tgtcaatacc atatcattca tctaaacacc ctccagtcca
    16621 atatatcatg tctgaaagga gcagacaaaa aaagtgcaat ttttacctct tacgaaaaaa
    16681 ggactgtgac aaaatttttg tcatagtcct ttttatgaat aaacggtgtt caatcagctg
    16741 accctcggta ttactcaaca aacggcaaaa tatggggagc tatttttcct ttgtcttctc
    16801 taatactcag gtcaaaacgc tgatttcaca acctctttag cctactattg aaaattacaa
    16861 cttacttgct gcttcttcat cgatgatcac aacaacattg tcgtgatttt gcaatacact
    16921 tgctggcaaa tgattcgtta caggtccttc aatcatccct ttgattgcat cagctttgct
    16981 ttcgccaaat gccatcaaga cgatttcttt acttttcata attgaaccga ttcccattga
    17041 aacagctttt gttggtacat cttctgcttt atcgaagaat cgtttgtttg cattgattgt
    17101 tgattctgtt aagtcaacta ctgaagtcgt tccgtcaaat gaagcaccag gttcattgaa
    17161 accgatatgt ccattttgcc cgattcctaa gatttggata tcgattggat gtgcatcgat
    17221 gatttgatca tactttttgc atgctgcttc cagatcttct gcttttccat ctggtacaaa
    17281 cgtttctttg aatggttttt tatcaaataa ttggacatcc atgaaatgac ggtagctttg
    17341 ttcatctgaa ccgcctagtc caacgtactc atctaagttt acagaagtca tttcactgaa
    17401 atccaaatcg cttgaagtca tttctttata taaagtaact ggtgtgcttc ctgttgccaa
    17461 tcctaatact tttgcacctt tgttcatacc ttctttgatg atttcaaatg ctttttttcc
    17521 gccttcttca gcgtttttta cacgaatgat ttccatagtg attgctcctt tatattttgg
    17581 tatagcccaa ttatagcatt ctttttttct ttttacaata attagtatag accaaattgc
    17641 atttttttca ttttcttgac aataaatagg aatccgtgtt aggtttcata agatggttca
    17701 atcaaacaat ccatgttgca tgaaaaccaa gcaagtgatt cactgtggac gctttatgtc
    17761 tgcagttttt ttatgaaaaa ggagttatta tgagtatact gacattaaac aacattaccc
    17821 agcaatttgg cgacaaaatc ctctatgaag gtgtcgatct gcaattaaat gctggcgaac
    17881 atcttgggct gattggacaa aacggagccg gtaaaagtac attgattaaa atcatcactg
    17941 gtgagatctt accagatgac ggacagatcc attggcaaaa aaatattcac aaaggttacc
    18001 tcgatcaata tgtggaagtc gatgaaacat taacaatcga agaatttcta aaaactgcgt
    18061 acgcaaaaga atacgaaaag gaagaaaaaa ttgcttttct ttaccaaaca tatagcgaga
    18121 ccttcgatga ttccttgctg gaaaaagctg ggaaactcca aacggaatta gaccaaggag
    18181 tgttttatca aatcgacacc ttagttgctg agatgagcag cgggttgggg atcgatgtct
    18241 taggtttaga ttcactgttg aaaaatctaa gtggtggaca acgttcaaag gtgattttag
    18301 caaaactact tttagaaaac ccagatgttc tgatcttaga tgaaccaacc aatcacttag
    18361 atgatcagca tatccaatgg ctgacgcagt ttcttcagga ttttgacggt gcgtatatcg
    18421 tgatttccca tgaccaagaa tttcttgatc agatcaccac ccatatcgca gacatcgagt
    18481 ttggaaagat tactaagtat actggccatc taaaacaagc attgaaacaa aaggaacaaa
    18541 atcgcgaaag ctatttgcgc caatatcatg ctcaacaaaa acaaatcgaa aagaccgaag
    18601 cttatattcg aaaatacaaa gccggttccc gatcaacgat ggcaaaaagc cgacaaaaac
    18661 aattagataa aatcgaacgg ctgacgcctc cagcttcagc aagtaaagct gtctttgatt
    18721 ttccattctc gcctattgtc acgacattag cagtggaaac aactgattta gtcatcggat
    18781 atgatcgacc gctacttgca cccatcaatt tgaccatccg ctttggtgaa aatattgcca
    18841 ttcgaggctt caacgggatt ggaaaatcta ctttattaaa aacactgatc ggtgagattg
    18901 aaaaaataag tggcgatttc cacttcccag ataacacaaa aatcaattac ttttcacaag
    18961 atctgtactg ggaaaatcca ttagaaacac cactacaata tttaagcagt caatttccaa
    19021 aagcgactat caaagaatta cgtcgccaac tagctaaagc agggttagtt aatcaattag
    19081 caagtgaacc tctcactaca ttaagtggtg gggaacaaac taaggtgaaa cttgcacagt
    19141 tgacaatgaa ccaaggtaat ttactgattc tcgatgaacc gacgaaccat atcgatcaag
    19201 aaacgaaaga aagcttacaa gacgggatac agaaatttcc aggaacagta atcatcgtct
    19261 ctcatgaaca agaattttat caagatcttg tgcaacgagt cattgagatt gaaccaaaat
    19321 aaacgtttga ttgaatagtt gaaaaaaagg agctgtgaca aaagttttgt cacaactcct
    19381 tcttctgaat aaatggtggc caattagctg accttcggta ttagctcaaa aaacggcaaa
    19441 atatgaggag ctatttttat ttggctattc ttattacttg atgcagaaca gcttttcaca
    19501 acctcttttc gtctattttt tattttcgag atttctcttt cctttaaaaa caactgtttg
    19561 aaagaagaac gcacatcctt gaaaaacaag cccgctaacc gttacaccta accagccata
    19621 ctgctgccac attgtcgtcc ctagcaatga accagccgca cctccaataa agtacataaa
    19681 cataaataca gtattatttc ggttgcttgc tgcttcacct agcccttgta ctcgtgtttg
    19741 attggcgact tgaccaaatt gattcccgac gtctaataaa ataatagcta aaagcaaaat
    19801 ggccaaatgg cttccgccaa ccaataaagc aataaagctt attgtttgca taacaagtcc
    19861 catatacacg atttttcttt cagaataaga atctgccagt cgtcccacga taggtgcagc
    19921 aactgctcca gacaaaccaa aaatcgctaa tatccctgct tcgaatgttc cccaattgta
    19981 ggcgggactg ctgatataaa aaatcaacgt agaccaaaag atcgaaaatg ttccaaacat
    20041 gaaaaatcca ctgactgccg cttctcttaa tagacgttga gaagcaacta aatgcggcaa
    20101 acttttaagt gaatcaaggt atgaaacagc tgtactactt tgctggacag aacgcggcat
    20161 tttccagtaa agcagaagtg taagaattcc gactgcacat aaagcaaata aatagatcat
    20221 ccgccaagaa aaaagactgg caacaatacc agataccgtc cgagaaagca aaatccccac
    20281 gagtaaaccg ctaagcaatg tacccatgac cttccctctt gcttttggtc ccgctagtac
    20341 cgcaccgtaa ggaatgatga tttgcggcac gatcgaaagt aatcctatta aaaaagaagc
    20401 gcatgcaaat aacgtaaacg aaggcgcaaa aaaagcggcc aacagagaga cggcagataa
    20461 cgctgccatt cgaatgatca attttggacg atccaccacg tcccctaaag gaactaaaaa
    20521 cagtaaccct aacgcatagc ctaattgggt caacatcgtc aatatcccga ctgcacttgt
    20581 gctaacagat aaactagctg ctacttttgt tccaatcggc tggatgtaat acatattggc
    20641 aacaacaacg ccacaagtga ttgataatag taaaataagc gaagttgtta aaggtttttt
    20701 ttcattactc ttcattgatt tcccccattt cctatcttag tttacaactt atggaaaaga
    20761 ttggaaatag aaaaatacaa ctattcgcca cacttattat ttgtgctttt gttttccttg
    20821 ttttttcttg cgatctttat aaatgaagac aactaaccct actagcacag taacacttgc
    20881 aaccaacgtg actgcagttt tgttatatcc gtgaaacaga gcttctccac cacacgcata
    20941 caacacagac gaagggatga ctccaatcac gatcgacaat atgatttgct gtagaggcaa
    21001 tttcatcgca tctgcagcaa aattgaccat agaagatgga ataaccggta tcatatagcc
    21061 taacattaca cctatttttg gatgtttcat ttgtcggatt gcttgcaccc aatgattcgt
    21121 ttcggttttc ttatctaaaa attttaagcg atgcataagg aaaattgcag tgatgttacc
    21181 aagagcatta cccaaaatgt tgatgatcgc acctgtcagt ggtccaaagc tcaaaccagc
    21241 aatgactcca actactgaag taggaatacc tggaacagca cacatcaccg ctgtcaatac
    21301 gatcaagagt atcgatgcaa aagtcccatg cgaacgaata tgtgcgagta gctctgcctt
    21361 actcgctctc ggatttaaaa ataattggat gtctgtctga tattctaaat acaaccgata
    21421 gcccactacc agtatcagaa tgattcccaa cgagatcaat atcaatcgga ttattttctt
    21481 tttcatattt cctcctgaaa aaaatctata ttcattaaat aatagtttaa cataaaaaca
    21541 aaaaagcacc gaaatccaac ataggatctc agtgctttta aatagtaaaa attatttaac
    21601 agttacagat gcgccaactt cttcaagttt agctttcaat tcttcagctt cttctttaga
    21661 tacgccttct ttaactggtg caggagcgcc atcaactaca gctttagctt ctttcaagcc
    21721 taaaccagtt gcttcacgaa ctgctttgat aactttaact ttttggtctc cagctgcagt
    21781 taattctaca gtgaattctg tttgttcttc agcagcagca gcgccaccag cagcagctac
    21841 agctacagga gcagcagcag atacgccaaa ttcttcttca atagctttaa ctaggtcgtt
    21901 aagttctagg atagttgctt cttttaactc agcaacgatg ttttcaatgt tcaatgccat
    21961 tataatttcc tccgtttaat tgttcttttt tatttaatgc tttatgcggc aattaagctg
    22021 catctccatc ttctttgtct gccactgctt tgacagcgta agccacgttg cggactggcg
    22081 cttgtagtac agatagcaac atagatagaa gtccttcgcg atttggcaat tttgccaatg
    22141 ctgtgatttc ttccaatgaa gagactttac cttcgatgat accgcctttg atttctaatg
    22201 cttttgcttc tttagcaaat tcgtccatga ttttcgctgg tgcgactaca tcttcgttac
    22261 tgaatgcaac agctgtaggt ccagtgaata cttcgtccat gccttcaagg ccagcttttt
    22321 tagctgcacg tgaaagaata gaatttttga taactttcat ttctacgtta gcatcacgaa
    22381 gttgtttacg taaacgtgtt acttcatcaa ctgttaatcc gcggtagtca acgactacta
    22441 ctgatgcagc tgctgtaaat ttttcgctta cttcatcaac gattgctgct ttttttgcga
    22501 taattgcttc actcattttt gagtttcacc tcctgaattt tgatggaaga gttttttgca
    22561 ctgaaaaggc aagtcacttt tatagttact ttgctcaacc agtattattc atcacctatt
    22621 cacttcgttc atagtgattc tactcgcttt gctcgaaagg aaactccttt cgctttgctc
    22681 aaccagtatt gttcatcatc tcttcacttc gttcatagtg attcacaata aaaaactcta
    22741 tgccaccgca gacatagagg gactattgaa tatattcaat aaacgtcctc ggtaggaaat
    22801 taaggcttga tgccacctac tgtcttcggt acaagttaat tattaacctc aactagctta
    22861 gcatgctaaa ctagttgagt caagaattat ttttcagttg gatcaatcaa cattctaata
    22921 tttaattaga aagaagcttg gtcaacatgg ataccaggtc caaatgttgt tgtgatcgtt
    22981 acatttttca tgtattgacc tttagctgct gatggtttag cttttagcaa tacatcatgg
    23041 attgctgcaa agttttcaac taatttttca tcgtcaaatg aaacttttcc gattggtaca
    23101 tggatatttc cagctttgtc cacacggtaa gttactttac cagctttcac ttcgtttact
    23161 gcttttgtta cgtccattgt aactgtacca gttttagggt ttggcattaa gccttttggt
    23221 cctaatactc gtcctagacg acctacagta gccatcatat caggtgttgc aacaactaca
    23281 tcaaagtcaa accatccgtt ttggattttt tgaaccatgt cgtcgtcacc tacgaaatct
    23341 gcaccagctg cttcagcttc ttttgctttg tctcctttag caaaaactaa aacagtttgt
    23401 gttttaccag ttccgtttgg taatacaaca gcaccacgga tttgttggtc tgctttttta
    23461 gggtctacgt tcaaacggta tgcaacttca actgttgcat caaattttgc aatgtttgtt
    23521 tcttttgcta aagctactgc ttcggcaaca ggataaactt tacttgaatc aacttttttt
    23581 aatgcatctt gcattttttt gctcttttta gccattttgg ttcctccttg attgtggtta
    23641 taacggttgt acctcccacg tgttctatat ctttcaatat agagccaact gagaagctgc
    23701 tgtcttaggg tgtatagatt attctacagt gatccccatg cttcgtgcag ttccttcaac
    23761 catgcgcatt gctgcttcaa cgttagctgc gtttaggtct tccattttta attcagcgat
    23821 ttctcttact tgatcgctag aaactttcgc aactttattt ttgtttggtt cgcctgaacc
    23881 tttttcgatt ttagctgctt ttttcaatag aacagcagct ggcggtgttt ttgtaacgaa
    23941 tgtgaatgaa cggtcttcgt atacagaaat aacaaccgga atgatcaaac ctgcttgatc
    24001 agctgtacga gcgttgaatt cttttgtgaa tcccatgata ttgatacccg cttgacctag
    24061 tgcaggacct actggtggag ctggagttgc tttacctgca ggaatttgca atttaacgat
    24121 tttttctact ttctttgcca cgagacatac ctccttaagt ccgtgatgtg gttaattgga
    24181 gatgcatatt tctcctccca cgttttatct gatctgaaaa aatccagaca aataatgtgc
    24241 aaaacaatgc acactggtac agtatagcaa atttatttgt tttttcaaga tttttttctg
    24301 ctatttttac attttgcttg aataaacgct aaatttattc taaaaaaaca acaatttttc
    24361 gttctcattt cttcttttat gttacacttg cgctagcatg gttcaacaga tgaaagcaaa
    24421 caataacacg gttttttaga cccttgtaca aagattccta cataacaaaa tgaggtggag
    24481 aaaatgaaag atttaaggta tagaagtgtc tttgatatta ttggacctgt gatgattggt
    24541 ccaagtagct ctcacactgc cggagctgct agaatcggga aaatcatacg tagtatattt
    24601 ggcgaacagc ctgattctgt agatatttat ctatatgaat catttgcaaa aacctatcgg
    24661 gggcacggaa cagatattgc attagttggc ggcctgttag ggatggaacc cgatgatgaa
    24721 cgtttagctg attctttgaa attggcatat gaagccggta tggaagtctt gtttgttcct
    24781 aagagtgaaa aagccgaaca tccaaactct gtaaagatgc ttctaaaaaa aggaacacga
    24841 aagctttcag tcactggcat ttcgatcggc ggtggcaata tccagatttc tgaattgaat
    24901 ggattcaaaa tttctttaag catgggtact cctaccttga tcgttgtcca ccaagatgtt
    24961 ccaggtatga ttgctaaagt gactagtata ctttctgaga ccaatacgaa tatcggcact
    25021 atgacagtga cacgggaatc aaaaggtgaa aatgccatta tgataattga agtagatgat
    25081 cctcaagtag aagaaacggt aaaaagactc aaacagctgc caaatatcga cagcgtaaat
    25141 tatttcgatt aaggagctaa aaaaatgttt ttatcgattg aagaattagt agatcaagca
    25201 aaagcttatc caagtgtagc agaattgatg attgcagttg aaatggaaat gagtggccgt
    25261 tcccgtagtc acatcatcga gatcatggaa aaaaacctct cagtaatgga acaatcaatc
    25321 aacgagggaa aagaaggtgt tacctccgtc acaggaatta ccggtggtga tgcaaaaaaa
    25381 ttagatgatt atttaaatga ggcagacttt ttaagtggag aaacaatctt aaaagctgta
    25441 cgcaatgctg tagctgttaa tgaagtcaat gcaaaaatgg ggttgatttg tgctacaccg
    25501 actgccggaa gcgcgggtgt tgttcctggt gtgctgatgg ctgtccgaga tcggcttgat
    25561 ttgacacatg aacagcaatt ggaattctta tttaccgctg gcgctttcgg gttagtcatc
    25621 gcaaacaacg cttctatcag tggtgcagaa gggggatgtc aagcagaagt tggttctgca
    25681 agtgcaatgg cagcagcagc tttggtttgt gcaaaaaatg ggactcctca tcaagcagca
    25741 caagcagtag ccattacatt gaaaaatatg atgggactga tttgcgatcc cgttgcaggc
    25801 ttagttgaag tcccgtgtgt caaacgtaat gctttaggct cttctcaagc ttttatctct
    25861 gctgatatgg cattagcggg tatcgaaagt gtcattccgc cggatgaagt cgttgctgca
    25921 atgtaccaag tcggacgtca aatgccgtcg attttcaaag aaacagcaga aggtggctta
    25981 gctgttacgc caactgctaa acgacttgcg gaagagattt taaataagag ggcgtgataa
    26041 agctccttaa tttcgagtat taagagatta gttatcttca taacaaaaaa cgaagagagg
    26101 actaattgcc cttctcttcg ttttttatta atccatcaat ttcgtatttt ttacttcatc
    26161 gatcgttttt gttcctgcaa gttgcatcgt gatcgacaat tctttgttca ggtgttcaaa
    26221 aacagatgtt actccttctg ccccacctag attcaaccca taaatcactg gtcggccaat
    26281 cgcaactaag tcagcaccac ttgccagagc tttgaagaca tgctctcctc gacggacacc
    26341 agagtcgaaa atcactggta cacgtttgtt gactacttcg gcaatttttg gcaatacttc
    26401 aaaggacgca ggacctccat ctaattgacg tccaccatga ttggataccc agataccatc
    26461 tgcccctgca gagatagcga ttactgcatc ttctggcgat tgtattcctt ttacgataac
    26521 tggaagatgg gtgatttctt tgattgtttt gatgtcatct ggtgtcaagc cttgttttgc
    26581 agctgcataa atttctgcga ttccttttcc ttcgccatta ccacttgcac tttgttcgct
    26641 atacgcagct aagttaggca ttggtaatgg aaattggaat tgattgatga cgtcttcttc
    26701 acggtaacca ccgagcgttg aatctgccgt taaaatgata gctttagccc ctgcttctac
    26761 tgctttgttc aaaatgaact cattgaatct gtcgtcttta ctcatatata attggaaaaa
    26821 ctgcggtgcg cctggcgctg catcggctgc gtctttgatt gtcgtatttg cataagtgct
    26881 gatggaaaag attgatccag cagcagctac tcctttagct gtatcagctt cccctttttc
    26941 atgtgccaat ccttgggccg ctgatggcgc ttggataatc ggtgtatcta attcaattcc
    27001 gaaaacagat gtatgcaaat cggctgagtc gattccgcgt aatatccgtg gcatgatttt
    27061 ctttgtatta aaagaagtcg tattttcttt catcgtccac tcatcttcag aaccaccgcg
    27121 aatatagcca aaagctcctg cttccatgcg ctcttttaca cgaccttcta gttaggcaat
    27181 gtttacaata tcgattggat gttcttcatt acttgtatga taagtcatag tagatccttc
    27241 tttcatcttc ttgattacat ataaatcata ctaaacttac aaaaagtaag caaacattta
    27301 ctctcagata cttttatcgc tattctttcc aaataaatcg acttacaagc tgatctactt
    27361 cttggttttc atgaagcata ctatgagagg cattttcacc tgtcactact ttttcctcta
    27421 tttcatttcc gcgttgcttc aacaacgcat agaccgctaa tgcactgttt aacggtactg
    27481 ttccatcact caagtctgtt tcatctagtt gaccagcaat caagaaaaat cgagtggtta
    27541 taggaatatt accgatcatt tgctggtaat cttgatagcg gttagaaacg acagcaggcc
    27601 cctttgctaa ctcatctgtc agagactgcg cactatcatc gacaaaatca ttaaaaggcg
    27661 cgccaattgc tgttaatgtc tgaacttgtg gcaatgacgt atcctgtcca tacgttccta
    27721 aatagcgtag tgcactaact cctcccatgg aatgccccac tatgttgact ttatctatgc
    27781 cgtagttttc tttcagatac aaaagacaag ttttgatcca ttctgcttga ttccactcgt
    27841 tatttttatt atcttcaaac aatacttgga ccatcggatt gtctgctttt ccagacaaat
    27901 ctcctgttgc ttgtatttgt ccatctgttc ctactgttaa aaccaattct tttactgctt
    27961 gctgattttt ttccaaacgc cgcaacatcc ctttaaagga attttctgtc ccgctgtagc
    28021 cgtggaaaaa aagtgttgga atagtggttt tttctatcac tttactggat tctgccgttt
    28081 tttctttatc agaaacttca gtagtattta tcttcgtcgt ctggcaacca cttaacgcaa
    28141 acaaactgat aaggactaaa gctgctgcag ttgcacgttt gcataaattt ttgattggtt
    28201 ctgtcataca cctcttcctt tccatataga aaaaagaaag acttgaaagg ccaatcatat
    28261 gatcgacatt tcaagtctct ttattaatcg attttatcta cttgatcgaa atcaagttct
    28321 gtactggttt cacgtccaaa catatcgatg ttgactttca atttttcttt ttctccgtca
    28381 acttctgtta cttgtccttc taatccagca aatgcgcctt cgatgatttt cacgacttcg
    28441 ccaacttcta cttctagatc attttgtcgc aggctcatac cgatagaacg caagatatga
    28501 ttgacttctt ctggaagtaa tggtgctggt ttgcttccgg ctccgtgtga accaacgaat
    28561 cctgtcacac caggtgtgtt gcggacaaca taccatgaag cgtctgtcat gatcatttca
    28621 acaagtacgt atcctgggaa tgttttatga acgatttctt tttctttccc atttttgact
    28681 tcagtttctt tttcttcagg aacaacgaca cggaaaataa agtcggccat tttcatactt
    28741 tgcgcacgag attcgatatt tgcttttact ttgttttcat atcctgaata tgtatgcaag
    28801 acataccagt ttttttcaaa agattccatt gaaggctcct catttcattg taaaataaaa
    28861 aaacctcagt acacccgaag tttttctttc gcttcattat agcactaaaa gtacgttgtg
    28921 gctagcgagt tattttaaaa tccagccaaa taagctttgg atggctgtat ccattacgta
    28981 aaacatcaat ccgaaaataa tagaagtttc gatgactact aacgtatctt tacggagttg
    29041 ttttctgctt ggccaagtta cttgtttgat ttcatctttt acgcttttta gaaatttcat
    29101 gagacaacct cccttgctac tgtttatttc gtttctttat gtaatgtata ttgattacaa
    29161 tatttacaaa acttattgat ttccaaacgt tcgccgcttt ttccttcact gactgatttt
    29221 gtgtagttgc gagacccaca aacggaacaa gcgagtgctg cttttttctt tgccatttac
    29281 ttctgccccc ttgctgagaa tcagacttat acttcataac agtatcacgt aactttttac
    29341 ttgtcaattt gtgaaataaa ctatctattg ttttggataa aattatgata tgattaattt
    29401 gaaattaagc taaaatgaga caattggagg tatagcgatg ctattaaaaa cacttgtata
    29461 taagaaaaaa gatctgacaa ccgttacaga gactagtaca ttagaagaag cattaaaaat
    29521 tttagaaact tccggatacc gttgtgtgcc gatcttagat tcttcaggta atattttccg
    29581 tggaaacatt tacaaaatgc atatctatcg tcataaagca aatggcggtg atatgacgct
    29641 tcctgtcact catcttttga aaaacgctac aaagttcatt tacctggata cttctttctt
    29701 caaagtattc tttacgatca aagagcttcc ttatattgct gtccttgaca gtgaaaatca
    29761 tttttatggt attttgacac atagtacgtt gcttaatatg ctctctcaat cttggagcgt
    29821 agaacaagga agctatgtac tgacaattgc ttccacagga aagcaaggag atttggctgc
    29881 tattgcaaaa atcatttcaa aacacagcag cattgccagc tgtattactc ttgatatcga
    29941 aaaagacgaa tacattcgac gtacattgat cacgctaccg gctaacactg aagcgaaagt
    30001 atgtgaaacg atcgtcaacc acttagagaa aaagaattat aaagtggtag aaattgaaaa
    30061 tttgcaaaac caagaagcat aatcaaaaag cgaaaaaaga aaacagctaa tctgctttct
    30121 tttttcgctt tttataatta gacacgcttt tcaaaatcaa gcgcgcgatc taaataatac
    30181 atcaatggtg ctgaaacagc catgacgata aactcactta atgcaagcgt gccataggtt
    30241 gtccaaaatg cttggccacc tgttggaact aacatataag caatcagtcc catgctgatg
    30301 gtaaagaaga tcgtgttcaa tactaaacgc atctttacat ttttcacttt gttttgcaat
    30361 aaagctgtca ggcctaaaga aagcaatgtt tggccgccac caaaaaccac atccatgata
    30421 ccaaaaccaa agaaggtatt atagacgatg accccgccta aaactcccca aagcaattta
    30481 cggttaaaga caactaaatg attcaaactt tctgaaatac gaaactggat cggccctgag
    30541 gatacaggcg caactaaaat agttaacgct agataaagag ccatgatgat gccatttaca
    30601 acgattacgg ataaccgttg tctgcttttc gttttttgca ttttctctcc tcttttctcc
    30661 tagttttttt aacgcgggat ggttgatgaa ccgcggttat gtgaaacaaa caataattat
    30721 aacagacttt tcatttattt caatccgtct tatctgcttt taaaaaagca aaagcttaaa
    30781 caatgtaaac gtttgctaaa aatcgtggga tatggtataa agtaagtgta aggggtcata
    30841 agaattccca gtaaagcaga cgaagtagga tctgcaagaa cagaattgtt gtgaaactta
    30901 aataaataaa aaaggatgtg ggaatttgag caacctctta ctagagaacg gtctagcaag
    30961 cagctgaaga tctaagtgga catgccgaac cttggaactt ctccttacgt aagtaatgga
    31021 tcatgcgctt gctaggcttt tttgtgtttt tcggtcttcg gacctttttc attttcctag
    31081 acttctgcta taataaccaa gaattaattt tgtaacagat ttttttgaaa aaacaagttt
    31141 ctttcattca aaaaatagaa aaagcttgct aattattggt taaccagcaa acaggagtat
    31201 taaaatatct tgttttattg aatagcagga ggaaatcatg aaattccatt atcatatatt
    31261 gatcaatcca tcggcaggca gcggaaatgg ctataaagta gcagaaagaa ttttaccggt
    31321 attaaaaaat aagcatattg actatacact tcattatagt gaatacaaag gacacgatgc
    31381 tgagattgct gaaactttgg caaaagaaac attgattcct tggatagaag aagaacagaa
    31441 aacaatcgat actttccccc ttttgatcat cgtaggaggt gacggcacct tacatcaggt
    31501 acttgatact ttctatcaga tggaagtaga attcccagtt gcttatattc cagcaggttc
    31561 tggaaatgat tttgctcgag gggcaggcct tccaaaaaat cccaaaaaag gacttcagct
    31621 gattttagca gctcaatcac cagaaaaagt ccacataatg gcttatgaag aaaaaataag
    31681 tgaaaaaaaa ggaatagctg ttaataattt cggtatagga ttagatgcag ctatcgtcca
    31741 tgcgacaaat cattcttcca caaaaaagcg attgaacaaa tacaacttag gatcattttc
    31801 gtatttattc tctattctcc gtgctttatt cactcaaaaa ggatttccaa ttctggtaga
    31861 tgcaggagga aaacaattaa gtttttcaaa cgcattttta tgtacagcaa cgaagcatcc
    31921 tttttttggc ggaggaatcg cgattgttcc aactgctgat gcgtctaaac cagtcattga
    31981 ttttgtcgtg gtcgaacgaa tcaatttctt taaaatcttg tggctcattc ttttacttat
    32041 acagaaaaaa caattgaaat cgaaatattt ccatcactac acaacaaaca gattacgtat
    32101 cgtttcaaca acaccgcaac atggtcaaga agatggagaa gaaatggaaa aacgaccttt
    32161 tgatatcaca ataaccacaa ctaaacagtt gttttggtgt taataaaaga ggttttgtca
    32221 gaagctacat ctggaacacc gtttattcgg aaaaaaggac tgtgacacga cttttgtcac
    32281 agtccttttt ttactatgca gttaattctt tgcccaattg ggttgccatc gatagtttct
    32341 ttctttaccc aaaataaatt ggatcattga aaacaccgca gcaaaagcaa ctaagacaca
    32401 accattgaac caaaaagatt ctgcaaatgt ttgattgtaa ctgagtgttt cactgatcaa
    32461 gttattattt tgaacaaacc aatatgttgg tgtgaatgcc gctattttgc taaccatttc
    32521 tggcaagtat tctgctggta caaacacccc accgataaag caactgcctg tgataaaaat
    32581 atctttgatc ccaccgctgg tttctgagtt ttttaccaat gaagtgatac aagccgaaaa
    32641 gctaatgatc ggcaataaaa acaagaaagt atttaaaata tgataccata ccgttatatc
    32701 ccacgaggtg tggatcacta acagaaccat tagaagtaag aagccactga acaacagcag
    32761 cgagtaacta atcaaactaa aggttacttt gcgattcaag tttcgtttgg taatgggcgc
    32821 actctggttt cgtttactga tctctttgcg attaaacgct agattgatga cgctgaaacc
    32881 gctaaaaatg gatagaaaca acccataaga caagaaatta aaggttgtgc ccgtcaacag
    32941 ctttttcatc cgctgactat atcccgcact tagctcaact tctccagtaa ccgagagtgc
    33001 catttgtgtc tgttccatag ctgcatcgat tgttttatct tcttcttgaa acagaatcag
    33061 tgtttgcaaa aaggtgttca cttgctgtgt aacaactgtt ttagaaaagg catctgggcg
    33121 actctgtatc ttgatcgtcg gcatctttcc tacttcgact tgttcggtaa agtctgcagg
    33181 cagatgtaag ataatgttta cacgattaaa ataaagagca tcatcgattt ctttttgtga
    33241 ggttccatcc aatgtaacga ctgtttcctt gtcattcaaa tatttacgaa ggccatcgac
    33301 tacaggcgac tcttcttcac taatcaaggc gattttcgca tcttgcagag aggtattttc
    33361 aacatcaata ttttgcgcaa aaaagaatgt ggcaacaaca gtgataatta cacctatcag
    33421 taaattcgat ttatttgctt taagcaatgt ccaaatcgtt ttataaagcg tcataacgca
    33481 cccctctttc catccaagca tttcctaacg caaaaaggaa aataaatccg atcaaccata
    33541 gaagattggt ataaaaacta gccaaatcag tgtagaaata aagtttatac aaactttcgc
    33601 tgatcaagtt gacgagattt aattgaccaa caatcggaat atgaagatca atctaatact
    33661 tcacttgttc cgaccccatc ataccagcaa aaaagctcat cgcaatcgtc actgaaatca
    33721 agatgctatc cttttgcacc agattcattt ttggtatcaa attaccaacc aatgtaccta
    33781 acaaaatcgc acacaacgac cccagagcgg taacaatcat caaccattgc caacgttcac
    33841 caaagtctac ttgatagata aaacgaaaga cagctaacat aatataaatc tctgtcaaaa
    33901 caatcgtaaa gcttgctgcc aaattagcga ttgaaactaa cgattgcttt ctaggaatca
    33961 aggacaagcg aataccattt gacgattgat ttgcttgctg atcctgtaca ttgcggaccc
    34021 cccacatcgt cccgtagaga atcgccattc caatcagagt gaagaaataa aaacttttga
    34081 aactcatatt acgacctgca tgaacttctt gaaaagatac ttcttgttca aaaacagtca
    34141 tgatgggcgc gagatcaacg ttctccactt ctgccacttt actcgaaatt ataccaatac
    34201 gctgtaaaaa ttgatccatg acgtttttca tcaacgtctg actcattcct gcttgaccca
    34261 catggagcga aacagatgaa ccatcaatga gataaaaacc agccaaatca tctgcattta
    34321 gcttttcatt cgcttctact tccgatagtt cctgtacttc aaataatggt ttatcattga
    34381 cttcgacttg ttctaagact gtggtaaaat tttccgaaag cgctgtttga tccgctttga
    34441 ttacaattcc agtattaatc gtttcgagat tgccaccttg atcaatctcg ccaaaggccg
    34501 ccataaacat caatcctaaa agaattggaa aggccaatgt ccaaaacaac atggatttat
    34561 ttcgcagcag tatttttgtg cgatatttat aaaaatgcca aaacattatt tcccctcctc
    34621 tagtctctca aatccttgcc agtaatctct aaaaagacat cattcaagga cgcttctttg
    34681 gttgctattt ttccgtaact gatcttttct tcttgtaaga ttgtaagaat cggcaacaat
    34741 actgtattta gttcagtagt tgttacttgg agctgccctt ttttataagc gattccatca
    34801 gaagctattg ttcgctgaat cgctgacaac acgttttctg ggagtaatgg gatgtcgatc
    34861 gtcaaacgat ccgccgtccg taccatatct tttagagatt ctttggttcc tttagcaatc
    34921 acctgtcctt gatccatgat cacgatctgg tcgcaaagaa tttctacttc ttccatgtaa
    34981 tgtgttgtat agacaatggt tgctccttgt cgattcagct ccttgatact ttctaaaatt
    35041 ttattccgac tttgggggtc tacagctact gtcggctcat ctaaaaaaat taaccgcggc
    35101 ttgtgggcaa tcccacatgc gatgttcaac cgacgtttca agccaccact aagttctcct
    35161 ggacgaaacg aaacatattt ttctaatccc actaattgaa tcacctcttc aatcaaggct
    35221 ttccttttct ctttttcgga aacatataaa ccgcaaaaat aatcgatatt ttcttgcaca
    35281 cttagttcgt caaagaccgc aacgtcttga ggaacgaccc caatcattgc cttgacagca
    35341 taattttcag gagtcattgt tgtcccgaac aatttaatgg ttcctttgtc ataatttaac
    35401 aaagaaagca tacagttgat ggcagtcgat ttcccactgc cgtttggtcc taacagacct
    35461 aagacttctc cttcttgtac ttgcagatca aaatgattca atgctacaaa atctccatag
    35521 cgtttgacta atttatcaat ttcgataatc atcatgaaaa actccttcca aatttcttgt
    35581 tgatctgact ataataaagt gcaagaaaag aaactagtga cgattggcta aaccacacat
    35641 gacatttgtc acaatgaagg agtctgctat gcataaatct cggctactca acgaaactag
    35701 ctttctactg gttatctcat tgcttttgct ggtaagtcaa ggattcgttg ctatgcaagt
    35761 tatctattta ttgatcgccg ttttattcac tggtgtcagt tatttactgc ctacaaagcc
    35821 aaattggatt ttccaagtta ttctatttct tttatgtgcc tttttacctg atcttgtcct
    35881 gtttctgcca gcgacgatgc gagtgatcgc ccctgaagaa agccaccttg attacttgtt
    35941 tttgttaggt tttttgttga tttcgacggt tggtaatcat ccccccatca aggtcgcctt
    36001 tgtcgtaatt ttgctgtttt tttcctttta cttacgaaaa aaagatcaac gaacgaccga
    36061 tcttgagaaa aagtacattg tctccaaaga tactcattgg gaaaaacaac aagagttatc
    36121 ggaacaaaat aaagcattgg ccctgtcaca agaaacacaa ttagccttgc aaattttgga
    36181 agaacggaac cgaattgccc gagacatcca tgacaatgtc ggtcatctgc tgtcaagtgc
    36241 gattttacaa attggtgcgc ttgaaatgat caatcaagaa ccaaaactaa aagaaccatt
    36301 agaaaattta agtgccaccg ttcacactgg gatggatcgg attcgtcaaa gtgtccatga
    36361 cctccatgag acatcgatct cttttcaaca ctccttagag tttctgatcg ctgattttcc
    36421 ttcttctgtt acgattgaag gaaacttgtt tgaaggattg aatgaaacgc agcaaaactg
    36481 cttcttaatg gtcatcaaag aagccttaac caacagtatc aaacatagtc atgccaaaac
    36541 cgttgtttta cattttcgaa cgttgccggc cttttatcgc ttgcaaatca cgaatgatgg
    36601 caccagccca caaaaaaatt ctgctcccgg tattggtttg aaaacgatgc gtcaacgtgt
    36661 tcaagaacaa aagggacaag tccatatttt ccaagaaaac cagcaatttc agttaacgat
    36721 cattttacca agggagggac accaatgata acagtagtca ttattgatga tgatccattt
    36781 gtgacgaaat cgttacaaac cattttagaa agcacgaaag agatccgtgt gttaggcatt
    36841 ggtcattgtg ccaaggatgc gctagtctta tacgaaaccc atcgtcccga tgttttgctg
    36901 acggacatcc gcatgcctaa acaaacgggc atcgatgctg ccaaagaaat tttggctaaa
    36961 tttcccaaag ccatcctttt gcttttgacg acattcaaag atgaagaata catccgcgaa
    37021 gcattttcca tcggtgtcaa agggtattta atcaaacaga acttgcaagc gattattcct
    37081 tctgtcaaat ccgcttataa tggacaggcc gtatttggta atgaaatcat cgagactttc
    37141 actcaaatga tgaagaataa accgacgatt gatagtcatg cttatgcttc ttttagtgaa
    37201 cgtgagcttg caatcatcaa agaagtagct gccgggaaaa acaataaaga aattgcagat
    37261 gccttgtact tgagtgacgg cactgttcgc aattacatca gccaattact agaaaagcta
    37321 gatttacggg atcgcacgca attggctatc tatttttatc agcatttgca ataagtctta
    37381 tctaacacaa aaaaacctga atgatgctcc ttcgcatcat tcaggttttt ttcacatctt
    37441 ctattcaatt gtcccgcaaa ccatttcctc acgattgaaa gaatcaagga ttcgcagggc
    37501 tgccaggatt cgttggattg ttcggcgtgt taggcggaaa aataggcgcc ttgtctaacg
    37561 ttttttctag ttttgattct tcacgatcgt ctcgttctac atcaggactt tcattcaatt
    37621 tgaattcttt ttccatctca tctaactttt taaagtcatt gccagattct tttgctaatt
    37681 tcgctaattt atcttcggtt tctttagcca taaagtaacg cccccctttt gatttcagct
    37741 tagcatatca cactgaaaaa acaaaagaaa acgctaacca acgatcattt ttagctattt
    37801 ctcatcttta aaatcaagca ttttttgccg gtataaaatc gtagggagaa ctgttttcca
    37861 taccaatcat cggatctact aactggttat cgatcacttc tgctgtaaga acgaaatctt
    37921 tagaaacagc aggttctacc tcttctttct tttcttctcc aacaaatgaa gaaaacagat
    37981 ctggttccac tgtttccatt acttggtttt tcgtttcatt cgtcccactg tcatcttcta
    38041 caggtagctt ttcttttaca acccgtggct cttttgtata gttcccatct tcaaatggat
    38101 catttccgac caaagaatct tcataagctg ctagtttggt ccggagagtg atattcattt
    38161 tatcattatc catgatcctt gatttcaacg tagtcatccg gcttgctgat tcattcgcta
    38221 cacaagtgac ataggcttgc tcttccccta acaaaatcaa cagttcctta ctgcgagtca
    38281 ctgccgtgta gagcaaatta cgctgaagca tccgctgata ttgatggacc atgggcaaaa
    38341 taaccatctt gaattcactg ccttgtgatt tatggattga gcaacaataa gaaagagtga
    38401 ttttattcca ttcgtttctt ttataagtga cctcatttgc atcaaactgg ataactaatt
    38461 catccacttt atcttcagaa tcttttgcca agatgatacc cgtgatttct cccatatctc
    38521 cattgaatac attcaattcg ggagtattga ctaattggag gactttgtct cctatccgat
    38581 aaacggtgtc gttccaatgt acttcctttt ttccaggttt ccctggattg aatatctcct
    38641 gcatcatttt atttaacgca tcgatccctg caggtccccg atacattggt gctaatactt
    38701 ggatatcttg tgcacggaat cccttatttt tcgctttttc cacaatttta gagatcaagg
    38761 gttcaatttg ataagcatca cttcggaaat aggaacgatc tttttgattc tttgtgaaat
    38821 cttttggcag acgtccttct ttgatctcat gggcaagagg aataatacta gaaccatcac
    38881 cttgccgata aatctgattg agttccattt tgggaatttg ttcgatttcc aaaagatcat
    38941 ggagtacttg accaggaccg acagagggaa gctgatcttt gtctcctact aagataactt
    39001 gcatattcgt cggaatcgct ttgaataatg tgttagccag ccatgtatcg accatagaca
    39061 tctcatcaac aatcaaaagt ccgccttcta attctttcgt actgactgaa ggtgtttttt
    39121 cccgtccatt cagccccaga agacgatgga tcgtactggc aggcagacct gtcgtttcgt
    39181 tcattcgttt agctgctcgg ccagttggtg ctgcaagtag aataggaaaa atttcttggg
    39241 tatattttga aggatccaat tccagtccgt tcaactctgc aaaaagattg acgattccgt
    39301 tgatcacagt agttttcccc gtacctggtc ctcctgttaa aataaataga ggggaacgga
    39361 ttgcttcagc gatagcttgt tcttgcgaag gtccatactg tatgccgaat attttttcga
    39421 tacgccgaat attcttctgc acttcttttt caggataatg gatttctttt ttacgactga
    39481 gaaggcgctg gatcgaatta ccgatccccc attcagaaaa gtacaaactg ttttcgtaaa
    39541 gattagtctc ttcttgttgt atctttcctt cttcaacaag ttggataatt acagtagcaa
    39601 cctgatcagg ctggatttca attgggcgac ttgtttctaa aatacggatc gtttgctgaa
    39661 gcaatgtctc cgccggtacg tatgtatctc ctgtttgaac tgcatgctga aaaatctgat
    39721 gcaagatagc tgctcgaatt cttctcggtg aatctgctgc aataccgatt tgttcggcta
    39781 gattatctgc acgtttgaac ccgattcctt ctatgtcttc gactagctgg tacggatttt
    39841 cttcgatgat atccaaagac tcgttcttat aggcctggta gatactgaaa gctaactgac
    39901 taccgaaccc gtaacgattc agtcccatga tcacttgatc catcccgtgg tttagccgaa
    39961 tcgtctcagc aagcatttct ctttttggct tcgtcaaacc ggagatttgt tttaataccg
    40021 aaggatcagc aatgattttt tcgatagcat cttctcccag caattctaca attttttctg
    40081 ctgttttctt cccgattcct gggaattttt cgctggaaag atacgctacg atcccatttg
    40141 cagttgttgg cttttcttgc tcatatcttt cgagtttaag ctgccttccg tatttaggat
    40201 gatccactaa ttctccataa aaacgataag tctcattttc ttgaatatcg ccgaaacttc
    40261 cggtgactac aatctctttt tcacggtaat cagctgtggt ttcactgatg tgtaccaaaa
    40321 gcactttgta aaaattacta ggattttgaa aaaaaatcgc ggcaactgta ccaacgaaat
    40381 aaggcatttc ttctggctgc atcggaagcc gcctccttct tctatagtaa aggttctggt
    40441 gctgtttcag ttcctaaaaa atctgtttgg ttccatactt tcagttcata tggcaataat
    40501 ctgcaaggct cttcagtctc taaaatcgtc aaactactat tgaacaatcc acccatttca
    40561 cgcaactcac ttagctcttt tcctgtcatc cattgaatgg ctgcagttaa agaagctcca
    40621 tgtcctacga ataaaagtgg gccatcttta tgttgggcaa ccgcatctgc tacaacagtt
    40681 tcgatacgtg tgattgccga ttcaatcgtt tctccgtgaa aaggagaagg atcatacaga
    40741 tctaaatgat tacgcaaatt cggcagatta tccggatatt tctggtacat ttcatcgatc
    40801 gactgacctt ctaaagtacc cagccctagt tctcttagct tatctgtata aaaaatctct
    40861 accggacgag caagctcttt gttgatacct tctgctgtat cacgtgctcg ctttgctgta
    40921 ctggaataaa ttgctttaaa aggaacatat tttacctttt tcccaaatgc tttgatttct
    40981 tcgtaacttt gtggcaaaag cggagaatcg ccattgctcc cttgaaaacg tctttcctga
    41041 ttccattgtg tcttcccatg tcgggtaaaa tatagttcca tacgcagcaa actcctgtct
    41101 ttcttttatt ttactctata ataaactgtc taatccagct tgtcattttc atagtgatgc
    41161 gtcaattcta aattagggaa tccttgctgg cgaagtgctt catacactat cattgcagct
    41221 gtattcgata aattcaatga gcggacatgc tcatcattca tagggatgcg taaacacttt
    41281 tcttcgtttt cacgcataaa tgtttctggc aaaccggttg tttcttttcc aaataaaaag
    41341 aagtgctctt ctccatcagc aaaattttcg tcactatata ctttatgggc aaattttgag
    41401 atcaaatgta gtttacgatt acctaaaaat gttaaaaaag cttctaaatt actgtggtaa
    41461 gtaatattta catcattcca ataatccaac cctgcccgtt ttagatgttt gtcatcagtt
    41521 gaaaaaccta gtggctcgat taaatgaagc ggagtattcg tggctgcaca cgtacgggca
    41581 atatttccag tgtttgcagg gattaatggt tcaaataaaa cgatatgatt catcaggatc
    41641 attcctctca tatttatgtt cgtttctatt ttctgacaat ttgatttttg cataaaaaaa
    41701 aacgtatcaa ctcggtgtca gtcactgcga gtcgttacgt tagtgaagct cttctcacta
    41761 acttttatca gaacaggaac ctgataaaaa ccaatgaaaa aacaacttgt tgctaatata
    41821 acaccctcaa cttttttttg caacctctac tcattaaaaa ctgctagaaa aacgttttct
    41881 cttagttcct tttaataatt ctatgtcaat tgtaatcttc ttcaaaggat tcttatataa
    41941 gtctgctttg attcgctctt ctacctgcca ttctaaaggt gacatggcca aaagatcttt
    42001 ttgattttcc tctggtatct caaattcata ggttacacgc tgacgttcag ttaatttcat
    42061 tgcttcagca aacttggcta ctacacgttc attggaataa ctctgttttt caggttgatt
    42121 cggataaaaa gcctgacgta gttcctttaa ataattttct tgtggcacca ccttcaacac
    42181 ttctccatct tctgagagta cacgttggaa ttcttggtaa tgagaaggcg aaaagatatt
    42241 taaaaccgcg ttgaatgttt gatcagcaaa cggcaaattg gtcaaatcag ctacacacca
    42301 aaatgcttcg gcagattgtt ctgtagctgc gtagactcct tcttttgaaa tatcaaatcc
    42361 aacagcattt tgaatctttt tcaattttga aagttcattc aagaagctac cttctccgca
    42421 gccaacatct aatagcgaga cttcttcagg taaatgctgc gcaatagtct caataacggg
    42481 ctgatacatg ccagattgga tcattctacg ccttggaacg aacattcctt gatcgtattc
    42541 tgttttaacc gcatgggata aaaaataaag tgttcctttt ttggaaaggt caaaacggtg
    42601 attatttttg catatcaagc cattatcaga cttttttact tcttcttggc aaaccggaca
    42661 gcggaacagc tgatgatttt ctgccaaaaa ctggcgtcct cggtcaattt tttttaacat
    42721 agttccccct catttctgtt ttatcttacc gttagatgct cactttggca actgctaaaa
    42781 atatgataca atgcctagaa gaaagtgaaa gataaaggag aagattagat gatcaaagaa
    42841 ttttgcgctg aaaactacac atctattcct ctagcaattg ctagaggagc cgatcggatc
    42901 gaattgtgtg acaacttagc ggtcggtggc acaaccccga gtactggtgt gatcgaagaa
    42961 acgttaagtt atgctgggga aaaagatatc cccgtaatga cgattattcg tcctagaggg
    43021 ggcgacttcg tctataacga tatcgaattg aaaatcatgc atactgattt gattgaagca
    43081 aagaaattag ggacggatgg cgtagtattt ggttgtctta ctccttcagg ctggctagac
    43141 gaagaggcct tagaactatt gatcgaaaca gcagaagggt tgcagatcac cttccatatg
    43201 gcttttgaca gtattcctga agatcggcaa ttcgaagcaa tcgattggct ggtagaacat
    43261 ggtgttgacc gtatcttgac tcatggcggt cctgctgaca aaactattgt agaaaatttc
    43321 ccacggctta aagaattgat tgcctataca gatggccgct taatcatttt gcctggtggt
    43381 ggtgtcactg cagagaatgc agcacatgta gctaaagaat tgaacgtaag cgaagtacac
    43441 ggaaccaaaa tcgtggatct tcagttataa tcttataaac aaaaaaacat ttgcaacagg
    43501 cataatgctt attgcaaatg tttttgtttt tttacataaa atagcccata aataaagaag
    43561 caatattgaa ataaatcagt acactcgtca aatcgctcaa agtcgtgata aagggaccgc
    43621 ttgctactgc tggatcaaat cctagacgat ccattagcat cgggattaaa ctacctgcaa
    43681 gattcgccac tgtgattgca aatagcatag ccatccctat gacaaacccc aagataaaat
    43741 tatgtttcca aaaacctacg attagaaaaa tcgtgatccc cgtaacagct cctgtgacaa
    43801 cgccggtcaa gacttcagcc aaaacaagtc gaacaaatcc atgatctttc tcatcagaaa
    43861 tcgcaagtcg acgaacagcc acagctagcg actgggttcc agcattaccg gcagttcctg
    43921 taatcagcga aatgaagact gctaaaatac tcgcttcact taccaagtct tcatagtgac
    43981 tgattaaaga agcggtcgac atacctaaaa acaacagagt gatcagccaa ggcaaacgtc
    44041 gagacgctgc ctttactgga ttttcattaa tttcttccac attgaccccg gcaagtcctg
    44101 aataatcgct agcagcttca tcatcaataa cgtcgatgat atcatcgact gtgacgattc
    44161 ctaacaaatg atcatcataa tcggtaacag gaagagctaa gaagtcataa tctctaaatg
    44221 tttgtgccac atcttcttgg tcgtcgccta catgaactga aagcactcgt tcgctcatca
    44281 gatcagaaat cattgcgtcg tcatcattca cgattaggtc gcgcagagaa ataaccccta
    44341 ctagctgacc ttcttgatta acgacataga tgtaatagat tgtttcagct acatctgctt
    44401 cgttcttcag cacgtacatc gcagagcgaa cagtttgatt ggctacgatc gaaacaaatt
    44461 cagttgtcat gatcgcgcca gccgtttcat cctcgtaatg gagaagttcc ttgatttcac
    44521 tggcatcgtc tgccgacatc aaacttaaat atttagcaat ttgcttttta tccagcgtat
    44581 taagcaagtc aacagcatta tctgtataca tctcagaaag catatcagct gcatagctag
    44641 gacgcatttc atctaggtat tctttcatat gttcgttgtc ttcttcaatc acatcgaaca
    44701 tatccgctaa ttctttaggc gacagatagg aatagatcag ctgcctgttc tcttctgtaa
    44761 gagattggta gaattgcccc tgctcataga tatgcatctc taaaaaactg tttctgaatg
    44821 cctgaatatt attttccctt aaatcttgag tcaactgggc aaatctttcc tctaattctt
    44881 gattttcatc caaaccaatc tcacctcgcc ttattcttca aaccgtctca caactgcctc
    44941 catgtctgcg gctaaaggct gcttgaactc cagcaactct tctgtaaatg gatggtaaaa
    45001 acgcagatca taacaatgaa gggcttgtct ttttattccc agatccattc gcccgccata
    45061 catatcatca ccgagcaggg cacagccaat tgcggaaaaa tgaactctta tttgatgtgt
    45121 ccttcctgta tgcagctgga tatcaactaa cgcgatttct gttagtcgct tctctatcca
    45181 gtactcagtc tgtgccgaac gtccttcatc agagaccatt cgcttcaata gcgaagaata
    45241 atctcgggcg atcggcaaat cgatatgtcc atgtgccgat aaatctgaaa gccttccact
    45301 gactaaggcc tgatattttt tcacaaactt cttttcacga agttgcatat ctaattttgc
    45361 gtgcgcaaat ccatgctttg caaaaagcat caaaccagat gtatcccgat ctagtcgcgt
    45421 caccacatgg attacttggt tttcgtaacc ttgtttttta taataagcct ttacacgatt
    45481 agccattgtc ccatttggat ggtattgggc aggaatagac gaaacgcctg ctggtttatt
    45541 tactaccaga acgtgttcat cttcatacac gatatcgatc ggtgtttcat ccaaaagtac
    45601 ggtttcatgt tctccttcag caggaatcac aatggttacc ttatcatcct tagctagaga
    45661 aaacaagaca ttttctactt gatcattaac tttgatttga ccgccttgaa attttatttt
    45721 cgctaacaga ccctttgaga tccctttttc ttttaaaaaa tattttactt gctgagaatg
    45781 atctttctca taatcccatg taaactgcat atcaatcctc actaataaag gcatctttca
    45841 cacgatgcca aaaatgcata tgtcgataag aagcaaaatg gatccgttct tctgctattc
    45901 gataataaat tgagcggata tttgcttttg cgacattcaa ttgatcaacc gttacaagat
    45961 aatcttctgt attttccaat tttatttcta gccattcatc atgggcaatc acgatcggag
    46021 aacccaaagt acgaaacact cgattattca gtgaagcaat ctctgccaac tgaaaggcat
    46081 tgatactagg atggatcaca gcaccgccga cacttttatt atatgctgtc gaaccagtag
    46141 gcgtagaaat cgtcaatcca tctcctctaa aactttcaaa cagctcgttt ttgatgtata
    46201 catcggctac catcgtacga ttggcccgtt taatcgttga ttcattcagt gctaaaaaat
    46261 gctggtccgg tgtttcatac aaataactga tccgaacatc cagcaaggga taactaacac
    46321 tttgttcccg gttcgttcgt aagctgtcta ctagttcttc cagctcgtaa tcccgccaat
    46381 ccgtgtaaaa ccctaaatga cctgtatgca cgcccaagaa acgcacatca ttcagacaat
    46441 gactgtagtg atggaacgcc gacaataatg tgccgtctcc gccgactgag atgaccaatt
    46501 ctggctcatg atcatctcgt tgaatccctg cttgttctaa aagtgcgttc aaacgttctg
    46561 tcacttctat agtctttgct tctttattat gaacgatcgc tactttcatc ccctgcctcc
    46621 tctctttcgc tttctttctt caaaagcgtt cgatagtaga catcatctga ttttcctctt
    46681 ccatgggaga ataaccgctg tgcttcttgg atttcttcac ggatactgga catctcttca
    46741 tccaactgat aggcagcttc tgccgcacgc tgaagtcgtt cactcatttc ttctggaaaa
    46801 acgccttgat atttataatt cagcgaatgc tcaatcgttg cccagaaatt catcgcaaga
    46861 gtccgaatct ggatttccgc caaaattttc ttctcaccgc tgatcagctg tacaggatac
    46921 tcgatcacca gatgataaga acggtagcca cttgcttttt tatttgtgat gtaatctcgt
    46981 tcttggagaa ctttcatgtc ttttctttta cggatgatct caacaacttg atggatatct
    47041 tctacaaact gacacatgat ccttaacccg gcaatatcag acatttcttc ttctaaacgt
    47101 cccattggaa tatgccgtaa ttgtgatttt gttacaatac tatcgactgg cttgactctc
    47161 ccagtgacaa attcaatcgg gacatgtcga ttttgttcac ggaactgttt gcggatcccc
    47221 cgcagtttca ctttcaattc tgatacagtt tgttcatatg gtgctaaaaa tgcttcccaa
    47281 tctcgttcca tagctgatac ctctacttca ttaacattca ttgtttattc taccatatat
    47341 gcaaagtttt ttcgtactct tgatttatgc attgaccaaa aaaagaaaat taggcaaaat
    47401 agacaaaaag gagtcgatca aatgacacaa atgcttgaaa tcgaatataa atctatgctg
    47461 acaaagcaag agtacgagat attcatcgct cactatcaat taacagataa agatttccgt
    47521 gtacagacta atatttattt cgataccgtt gatgaacagc tgaagaaaca aaattgtggc
    47581 ctacggatcc gtttcgttgg tcatcaagct gaatatacat taaaaacacc tgctgaaaaa
    47641 gggcgtctcg aaacaacgga tacctttata acagaagaag cagaagcatt tatcttcgaa
    47701 aaacgtctgc ctcgttcagg cgcagttttt caaaaacttt ctgatttgaa tatcgatcct
    47761 gcttcattaa tccaaaccgg aaagcttaca acaaaacggg ctgaattccc tattgaagaa
    47821 ggacttttag ctattgatga aagctgggga gacaatctac acgattttga actggaacta
    47881 gaggtagggg atgcatctgt gggaaaaatt gcttttataa attttttaaa acgtttttct
    47941 ttaccttatc gtcctgctaa gaacaagatc caacgtatgc ttgaagctaa aaattagaaa
    48001 cctttcattt tcacaaggca cttgagttca tttttttact tttttctgtt aagttatagg
    48061 atgtgaaaga atctagtcac tagttgtata gaatctattt tgggggagat tcatatgatc
    48121 gaaatctatt tatttgttaa tcctttaggg gaatactgtt tcgaaatgga acaacagtta
    48181 ttacaattta tcgaagaaga gtacgggaca ccatcaaaag aaaagatgca atttcgcttt
    48241 cttcctttgg tcaatttgca gacaattggg gatgtcatgc aacaaaaagg aatttctcag
    48301 aacaatcttg aggaacgtaa tcacttattc tcaatgactt attctgcagc attggactgc
    48361 aaagcggcgc agtttcaagg aaagaaaaaa ggccgccgtt ttttgatcaa attgcaagaa
    48421 gcagtcggct gtaatgacat accatattct caagaacttg ctgaatccat atttgaagaa
    48481 atcggcggcg atttgaatat gtttaaagaa gatcgtcagt ctgacttcgt taaagaagta
    48541 ttcttttctg atcaaaaaat tgctcgggaa atgggcatca caaaacaccc ttctgcagtc
    48601 gtttacaatt atgcctgcga ccgtgatttt ggtgttttag tagaagtaaa aggtacaagt
    48661 agcctttgga gaatcacaga gctgtgtaaa acaacagata actcatatca agtttttaat
    48721 ggtgaacatt tacatacaaa tgattctcag ttccattcaa gaactagcca tttacacttg
    48781 ctttctaatt aaaaaaatac gtcgactccc ttacaagaga gccgacgtat ttttttcgtt
    48841 tctattcgag aaaatcaaaa atagaaagcc ttataaacga tcgatcaatt cttctaattc
    48901 atttagacgt tgttcaaaca tcgacattgc atcttcaata tatgcagcct gtgtcatatc
    48961 aactcctgct tttttcatta cttccacagg ataatcgctg ttacctgctt ttaggtaagc
    49021 caagtagttc tctagtgcct ctggttcctg gtttagtatt ttcttcgcca gtgctgaagc
    49081 agcagaaaag ccagtcgagt attggaaaac atagtaatta taataaaaat gcggtatccg
    49141 tgaccattcg aatttaattt ctgggtcttc ttcgactgct ggaccataat attttgcatt
    49201 caatttacca taactatcac ttaggtattc actagtcaat ggcacacctt tttcatcttc
    49261 cgtatgcatg aaatgctcga attcagcgaa ttgtgtctgg cggaaaactg ttcctttaaa
    49321 cccatccaag taatggttga gtacataagc ccgtacacga gggtcttttt ctgtttccaa
    49381 taaatactcc gttaggatat tttcattcgt tgtcgaagca atttctgcta aaaagatgga
    49441 gtagtcgccg tacacataag gctggttcga acgagtgaaa taactatgaa cactatgtcc
    49501 catttcgtgg acaagcgtaa atagctgatc cagcgtatca tgccaattca ataaaatata
    49561 tggatttgtg tcatagcttc ccgaagaata agcaccgctt cgtttccctt tattttcgac
    49621 aacatcgatc caacgttcag agaatgcttt ttctacgatg gccatgtatt cttcacccat
    49681 tggtttcagt gcttctaaag ctttttcttt tgcttcttcg tacgtaaagg taattggagc
    49741 ttcccctaag accgatgtat aaagatcata catgtgcagt ttttccactt ctaataaacg
    49801 tttccgtaat tccatgtatc gatgtaacaa aggcaaatgc ttgtttacca cgtctaccaa
    49861 agtatcgtat acactttcag gaatatgatt attgctcaaa gacgcttctc tggcagagct
    49921 gtaattacgg actttcgctt taaaattatg tccttttata tgtgtgccta aagtagaagc
    49981 aaatgtattt ctaaattgtt cgtaaacact gtacaatccc ttaaatgctg cttcgcgcac
    50041 ccttcgatcc gtgctttcta gcaactgacc atacacgcca tgagataatt ggactatttc
    50101 accattttct ccttcaatcg ttggaaaaac tagatctgca ttattcaaaa cagcaaatgt
    50161 atcacttgaa gcatcaaaga tttcacctgc tccagcaaga agagattcct gctcagcaga
    50221 taagacatgg gctcgattat ctactatttg ctggatataa tggcgataga cttccaattt
    50281 tggttcttct ttgaaatatt gccaaatctg gtcatctgac aattgcaata tttctggttc
    50341 aaaccaggaa acggcttcac taactttcga aaacagactg cttgctcttg cataaagcgc
    50401 ttggtaatct gtatttccag tgtcttgatc gtttttaagg tgcgcatata cataaatgac
    50461 ttcagtttgg cgataaaccc tcaatacgaa ttcaatcgca tttaaaaatt gagaagcgcc
    50521 ttgatcaagt gttcctttgt gtttttcaga ttgttttaac tcttctgata attccaaata
    50581 tttctcatca aactcttggt cgcttgaaaa gatcttggtc aagtcccaag ttaaattttc
    50641 aggcaattct tctcgttttg gcaactgctt tacttccatg aaatccactc cttttcttcc
    50701 cttagctcta tctatcaaaa tagatcatag tctaacatcc acatgtcaca gcatctaact
    50761 tttctactca ttcatgtgtc tgcttccatc aattttagca taactaaatc ttgttttaca
    50821 tagaaaaccg attcctagcc tatttttata cttactattt tttcaaagaa gacaagtgta
    50881 tgcattcgtt aaaaaactgc tgatagacca tctcttcatc aatcatagga aaaagccatt
    50941 cccttttatg ttcttttatt tggcaaagcc atgagttgaa atcaggaact ttctggtttt
    51001 ccaaggcttc ttcgtacaac attcgataaa gaaaaacctg ttcttgtaaa taaaagaaaa
    51061 accgactttt ttgatagatc cacgatgata gatgcaaaag atgtttatga cgcaagtagc
    51121 attgttcttg tatggatact gtattctttt gcttgtgaat aagttggcgt gtcagccatt
    51181 tcttcccatc ttcactcact ttttctattt ttttcatttg gttcatttta atttcgttac
    51241 tagtgaatat ttctttaagg tccctactag aaaaagtcca gcagctactg caaaaggaaa
    51301 tatgccctga tacagtctct gtaatatgat gatacaaata aagcttttgt ttcttgagat
    51361 cagctttcca gcaatgcact cctctttttc tattatagta gcagcaactt ttttctatca
    51421 atgagaattg cgattgtcca agaaaagaat taccaagtat ccaccatact tggtaactgt
    51481 tattcaaata attttgggtt ctttcaataa atctctggtg agacagtcta gaacattgga
    51541 tttctattgc tagattcgcc aacaaaatat ccggcctttg ccgcaacctc ggcaaatagg
    51601 cttccaaaaa tactggttct actgactgtc ccagccaatc catgaagcat tcctttaact
    51661 gtaagtgctc ttttgattct ctttcactaa agaccgaaca gttatctgat ttttgatggg
    51721 caaaatgagc acattttttc tttccctttt tcaaaatcac tctttttcga cagccacgac
    51781 aataatattt ctttcctttt tctgcatgtt tagcaaaaca gcacttatta tattcattca
    51841 ttgcaagcag catttttctc cctctgaact tatttacgtc taagaattta tttacacgaa
    51901 aaaagagggc gtgaaaaagc tattctgcat caagtaataa gaacagctaa acaaaaatag
    51961 ttcccaatat ttttcgtttg gttgggcttg ttaccgcaga tgcaagcttt tgaacacatt
    52021 tatacgaaaa aaagactgcg acacaatttt tgtcacagtc tcttactata atgctgattt
    52081 atacaaaata aaatttcgtt cgctcgatag cattacgcgc catcagacat tgtccatatt
    52141 cattcaatgt ttctggtgta cgatcgctct tttcagcaaa ctccaaaatt cgagcaatct
    52201 gattctctac atccgcttgg ttgagatttt ccatccagaa gtgaacgact aggtaatagc
    52261 gctcttcgaa taaatacaaa tcagtccaag cagactctag ttcgacatct gttgcaagtt
    52321 ggatcacttg ttcaaaatct tcaaaagcaa aagttgcttg tctttcctgt tcttctaggg
    52381 cgcttccaga taattcttcc tccggatcgc tgccaataat ctgctgacga agaaagtcac
    52441 tcacatcttc tgaatcaaca gtagaatctt ctgattgaga aatttcttca tccggaagat
    52501 ttttactgat aaacagttct aatccgtctc cttttggcaa aacttggaaa gtgacagctt
    52561 cgcttcctcg gaactcctct tcgatatcaa cttcttccaa aatactataa aagaaatttt
    52621 cgatttcttt gtgattgcca agtaaatcca aaaatgaaac gccccgttcc tctaaatctt
    52681 catgaccaat tagtacacgg atcgtatttt cattaatatg ttccatttcc attttgctac
    52741 acctcacttt gccacaatgt ttaatataga ttcattgtag cgaaatcagc ttaaatgtaa
    52801 agaaaaaaaa tctcgctgtt aagcgaattt aataaaacca gcggattttt caacctttca
    52861 agctatctta tttaactata acatttttgg cagacgaata ctatatagcc gacttttcag
    52921 ctaattttcc ctctctattt ttcgtgcaat catcatcttc tactaccttt ttatacatct
    52981 aatcaagaat actttttgta aaaacaaaaa aacttggaaa aactatcttt gtaatagtct
    53041 tttccaagtt tcgtattatc cttctataat ccagccatca attgtgcttg acgtaattct
    53101 aattgtcgta catcgcgcgg taggaaccga cgaatttcat cttcattaaa accaacttgc
    53161 agacgtttat catcaatcat gattggacgg cgaagcaatc caggattgtt ttgcacaagt
    53221 tccaataatt cttgtaacgg cagatcatct aaatccatgt tcagtttttg gaatactttg
    53281 gaacgtgtcg agatgatttc ttctgttccg tcttctgtca tttgtaaaat cgcttttaat
    53341 tcagaactgt tcaatggttc tgaaaaaata ttacgttcaa caaatggaat ctgatgttct
    53401 tgcaaccacg cacgagcctt tctgcaggaa gtacaacttg gggaagtata taatgttaac
    53461 aacgtgcacc actccttttc gtgataagaa tcactttttt gtaacagaag atcataataa
    53521 tctcccatct gtttctatta tacataatca acttttaaat agctaccttt ttttcataat
    53581 ttttttaaaa aaatgaaagt tatctaaggt taatatacag taaaaccagc attctcgctt
    53641 tttttatcat ttaaaaatta gagttttcaa atctaattca aattttctaa acatatgaaa
    53701 cagcgtataa aactgtacta ttattttatc tcaaaagcta aatgaaaccg atttcttaag
    53761 attttttatg ttttttattt ctttaatagt aatgttttct gtcattttaa ataatactgt
    53821 tctttattat aacgcttatt ttctctgtta tataagcgta gtattttaaa gcaatgatta
    53881 ctaaataaaa tttactataa acaaataaat caaataacgt tattttatgt ttgaatagtt
    53941 atattgagac tgtattaaaa aaataaatct ttcgaaaatt ccacagagat tgcattaaaa
    54001 taaatcaatc gacttctacc ataatgatta atttgttcat caaacttatt gacgtgtttc
    54061 acgattttta gtgaaaaaaa ctgaaatata aaaaccttat tctgtcaagg aaatagaaat
    54121 atagtaagaa aaacctttat ttatcagctt ttttagacaa ttttttctgt tacaatagtc
    54181 aaggatttgt gaaaaaatca atgaaaaccg aaaggcgtgt aaaattttga ttaaatcagt
    54241 tgtgtttgat gttgatgata cgatgtatga tcagcagcag ccatttcgaa acgcggtcaa
    54301 aagagtcgtt ccgcttgttt cagatgcaga tatgcatcca ctatatatcc ggttccgcca
    54361 tcatagtgat gaaaacttcc caaaagtaat ggcaggagat tggacactag aatatatgcg
    54421 agcacatcgg atcagccaat cactaaaaga tttagactac cctcatatta cggaagaaga
    54481 tggcctctta tttcaaaaaa tttacgagga agaacttgat aatatctgct tgcatgagga
    54541 ggtcaaaaaa accctcgatt tcttgaagga aaagaatgtc ccattaggaa ttatcacaaa
    54601 tgggccgact gaccatcaga caaaaaaact gaagcaactt caattgaaca attggattcc
    54661 ttcccgcaat atgctcattt ctcaagcaac aggtttccaa aaaccagaaa aagagatttt
    54721 tcagctggct gagaaagaat ttcatatgct tccagaagag accttatacg ttggcgataa
    54781 ttacgacaat gatgttctag gtgcaaaaag tgctaactgg caagcgcttt ggttcaacca
    54841 tcgagaacgc aaaattgaac agactccaat ttgcgatatc gagatttctt cttttgatca
    54901 gctgttagag acaatgaaga caatctttgt ataaccttta aaaatagaaa taaaaaaatg
    54961 atagcaagga agctgggata aaatggaatc ccagcctcct tgctattttt taaatcaaat
    55021 aaacaatcgc ttctttagaa aggctttctt acccattact gaacgctttt tcgagtctct
    55081 tactcctcga tttctcctac acttaaaatc atgcggatgt cttcttcagt cagtttcgtc
    55141 aactgttctt cattaccttg gatcactttt tggaacagtt cgcgtttttc ttgctggagt
    55201 gaatccatgc gttcctcaat cgttccttca gagatcatac gccacacttc taccacattt
    55261 ttttgtccga tccgatgtgc acgtccagca gcttgttctt caatggcagg attccaccaa
    55321 aggtcataca agatgaccgt atctgctccc gtgagattca atccagttcc cccagccttt
    55381 aaggaaatca gaaaaacatc tttttcgcca gcattaaatg cgtctaccat acttaaccga
    55441 tcttgtggtt tcgtactgcc tcttaaataa aatgtcgaga tccctagctc ggctaactct
    55501 tcttgcaaga tagtcagcat ccctgtaaat tgagaaaaca gcaaaactct tcgtttgttc
    55561 tctttggcag ctaccagtag atcttttact tgttcgagct tgccggaacc gccttggtaa
    55621 tcttcaataa acagacgagg atcgcagcaa atttgtcgca gtcttgtcag accagcaagt
    55681 atcccgatcc ggtttttctt gaatgcttca gaatccattg atgtgatttc ttcacgcatt
    55741 tgacgcaagt aagctaaata aacagttttt tgttcttctg taagtgcaga atatagattc
    55801 atctctgttt tttccggcaa gtctttcaac acagtttgtt tatctcgccg taaaataaac
    55861 ggtcgaatca tttgcgcaat ttcttctgcg gcaagttccc tgaattttgt tttagtcggg
    55921 aaaaatcctg gcataatcgt tgcaaacaat gaccacaatt cttctaaatt attctcgatt
    55981 ggtgtcccac tcagtgcaaa ccgctgaggt acagctaatt ctctcaatgc ttgtgcagtt
    56041 ttcgtactgc tatttttgac catttgtgcc tcatcaagaa tcaaataatc aattttttgc
    56101 gactgataat tagctagatc ctgtcttaag ctggcataag aagtcactcg gatatctgtg
    56161 tctttagcca gtaattcttc acgttctttt ttattcccat tgattacttg gatacttaaa
    56221 gaaggggcga attttctcac ctctgcctgc cagttgtaaa ttaagctcgc aggcgctacg
    56281 atcaaagcag agaagctttt ccgttcttct ttttccgaaa gtaaaaaggc aattgtctgt
    56341 agtgttttcc caagtcccat ttcatcggct aaaataccgc caaactgata atgacctaac
    56401 atcttcaacc atcgaaaacc ttgcttttga taatctctca tcgttgcatt caatcctttg
    56461 ggaagctgtg cctggtatct ttctggatga atgagatctt gtaccatcgt ttggaacgat
    56521 tcactaaaag tagcattgct tttttccaat tgattttgaa tgatcaatcc ttgattttta
    56581 ggtacatgga tcgttccttc ttctgtacgt atcgattccc gtaattgttg caacacttgg
    56641 cttgtttgtt gaaattcttc tgaatcaaaa gaaagaacct gaccattttc taatgtataa
    56701 aaagcatcat ttctcagcaa gctttgcagg acatgatcga tttcttgctc ctctatccct
    56761 gtcacatcga atcgaatatc gagccatgaa ccggtctcgg ttacttcgat tttcggttga
    56821 tgtttatgcg catctaaata caactctcgc aattttcttc caagtctgac ttcaccaaac
    56881 tgacggaaga cagatagttc tgtgcggaaa aaggcatata gttcttcccc gcttggcaat
    56941 ggacgttcat aaccagtttc atttttctgg tagcgataca ttctgaatag atcaagtact
    57001 cgtttctctt ctactgtgtc acgtaacacc tgaaaagcct gttctgtcga gacctcatgc
    57061 ttcgggtcag tcgaatagat gacttcacca tagacgaaat cgactcgagc ttggattttt
    57121 ccttttgctt ttcggaaaaa gaaaataaat tcgacgggga tatctgctac ttcctcttct
    57181 actgcagggg caatagctac gtcgccgatc tctgacagca gagggataat ctctttaaac
    57241 aaagacggta attctttttt cttgaacact acttctggtt tctccaatcg gcgaatcaat
    57301 tgtttccaag tttgataaac cgtttgttga tatttcgtca gagaataaaa tgtcccttgg
    57361 ataactcccc actgataatg cataaagaaa aaatcaaaat cattcaatgc ttgcagcaaa
    57421 taatcttctc caaatttttc cactttgaat gataaaggtt tgttttgatc ggaaaattgt
    57481 attccttgat cgttttgttc atttatctgc agatgcaaac gtgtagtctg attcatctgc
    57541 tctaacagga agcgggcttg ttctactggg agaagcagat atcttttatc tagttttcct
    57601 ttgacttgta agccgttcgt acctaataat tgatgcgtct gagcacttcc tgcaagatgc
    57661 gtgagtattt tttgatcttc tttttgaaac gcccgtttat ctagacgaaa ctggtactgt
    57721 ttattaacag tgtaagtttc tttttctgtg taagcttgta aaaaatcata gatgtttttt
    57781 acgatatatg tttttttcgg tgatgccaat gaaccgatac gcaagtaaag tgccaaaata
    57841 gaaagctctg ggtgatactg attagtctca atcgtttcta cttggtattc aataatcaaa
    57901 ggttgcaccg cttgaggatt gttttgtgtt tttagacgag aaaaaccttt tgcaatgatt
    57961 tctccctcac ttgttgcttt taccggttct agcattggct ggtctttttt catgatacga
    58021 gatagatttt tcgaccgtaa ataaagttcc acagcaactg tatgcttaca atatttatgt
    58081 tcctcccaat agggacattg gcagtaatct atctcttttg ctgtaccatc caaatcaacc
    58141 atatacaatt cactgcccaa gacttctgca tgccacacgt tttcttcttg gtcagggaca
    58201 accgataaca ctcggccttc ttgcaagtat tgacgtccac gtgcaatgac tttttctgga
    58261 atactccatt tcatagttac caatctccct ttttatccaa gttgatagcg tattttgctt
    58321 tgtccgctac cttctgtatc aattcttatt tgttgtaata ctcgttcttt caattctctt
    58381 acatgactaa tgatgccgat cattcttcct tcactttcga tcgtttctaa agcttccatt
    58441 gccatttcca aagcttcttc atctaatgac ccaaatcctt catcaataaa caatgcatcg
    58501 attgctacac caccagcttg tgtctggatc acatcggcaa gagctaatgc taaagaaagt
    58561 gctgcaataa aactctcacc gccagacagg gtatgcgcac ttcgagacat acctgcctga
    58621 tcatcataga tattgatttc taatccggtt ttccctcgat aactgccaat ggtatccgct
    58681 agctcaaatt gataacgatt tttcgttaaa cgttggagat gatcatttgc tacttgtaac
    58741 acttcttgaa gataaacctg aagcacatac cgttccaaac tagtcttctt aggattttct
    58801 ccgttgaatg tttgcgaaag ctgctgtaat tgcgtaagct catctaattt cgtctggctt
    58861 gtgtgataaa tcgaaagaca ttcatcgtag attttttgat tactaatttt ttgttcttgt
    58921 aaaccgtata tcttttcttg ctttatttcg atcatacgtc ttatttcttc taactgttgg
    58981 ctgatctctt ctgtatctgg gaatgtctca gttagctgga tattttctaa ttgacgcagc
    59041 cggtcagctg tcactaattg ctcttcatga taagaagtaa ctgtacgttg gttttcttta
    59101 tattgtgctt gctgttgtgc aaatgcacag atttcttcaa ttgttgaaaa atacgactgg
    59161 ctttctaact ttttagctat tctttcttgt tccttttcta ttttttcatc tattttttct
    59221 atttgttcat gttgaagatc aagctgtgtc cgaagcgtat gaagatcttg caacaattgc
    59281 actcctgctt tctgctcaac agctagttga ttcgagtctt cttctaactg tttttcaagt
    59341 cgtcgtatct cctcttctaa acagttacta tccgtatctt gcaattgttg ttctaaactt
    59401 ttgatttctc cttgcagttg ctggagctga ttattttttt ctgtctgctg ctgtttgtag
    59461 acagctaatt gttgttcgag cttttctgct tgttgtctta tttcttccag ctctattctt
    59521 gcattggcca tcttgctttt tcgtctatct aaagattgtt cgattactac aagagttgtt
    59581 tttgtttttt gttctgttat ctcaggaaat gcctttttca aagcctgttg caagtgttct
    59641 tcttgttcag ccaattgtat attcgttgcc atgatttttt gttctaaatc tgataattgt
    59701 tgttgaagat tattttcatg tgcttcactt ttggcaatga tttgctgagt tctttctaca
    59761 gcagactcag cttctgccag ttgttgttct acttttaaga tatcttcctt atttggctgt
    59821 tcgtgtttta attgttgtat ggggtgttcc gttgatccac aaacaagaca tggctcccct
    59881 ggacgcaaaa aaagctgaag acgagcaatt tgctgctttg cccattggct tttcagctgt
    59941 tctgcttgtt ctgtctgttc tttcaatagc tgactatttt ttgttatttc ttcagttgct
    60001 tttttgagtt cttctcttat ctgtgcgagc gacccagtgt cttttgcttt ttgtttttct
    60061 atttcttgct gcttttcatc tagatatttt aactgtccaa aagcaagacg atcttcttgc
    60121 agtttttcct gatccagtaa attttcttga agaattcgag ttctttcctg atagatagcg
    60181 agattttgat acagcttctc ggcattcaat tcttctttat ccaatgaaat tgttaattgt
    60241 tctgcgtctt gttttttact acgtaaggat tcgacaattg gcaccatcat ctgtttgttt
    60301 tgcagttttt gagcagcttc tttgattttt gtttgtcggc gtacgcggtt tgcttcattt
    60361 ttttgccact cttcataatt ctgcgtagtc atcgctagtt tctttgtttg ctcactactt
    60421 ttttgtgaca gttctatttt ttcaactttt atttcttgta ggcgctggat tggttcgact
    60481 aatcgttgcg taaattcata atacccaatc catcgtttct tttcctctat ttcgtctttt
    60541 tgagccgcta attccttttg cttgtttatt aatatcgttt tttcttcata actttttttc
    60601 aagctttcaa aacgatagta ggaattttct agttgctttt gtttttcctg aagttccgtt
    60661 agagcttctt tttcttccgt gatttgtttt tcgagtattg cctgatggtt tgtccattgg
    60721 gctaaaacgg cttcaaaccc tgctgctggt tcctcttctt tgactaaaac aaaccttttt
    60781 tgcagaagat gcagctcttg ctctaaatga tccaattttt gttgctgttg ttttgctttt
    60841 tcttttaatc gctcattgaa ctgttggaaa aattgagtac cgaataaatg acgtaaaaca
    60901 gtctctttat cactgcttga tgaaaccaaa aaattacgga attctccttg gggtagtaaa
    60961 acgatttgag aaaactgttt cgcatcgaga ttcatcagtt ctctgatcaa ctgatctgct
    61021 tctgtacgtt ttgtgatttg ttttatttct tttcctttcc catcaaaaat ggtcaacgtt
    61081 actttggctg cctgtttttt tgttccgttt ccttttcgtt ttgctaaaac ttgttctggt
    61141 tttcgttcga tttcatagct catctgctga tgttcaaaag aaaaagtcac gcttgtttct
    61201 tcgtctggtg tagcaaacaa agaacgcatc tcttttccag agcgaagtct tccggaagtt
    61261 tcaccaaaaa gtgcgaaggt gatcccatca aaaatcgtcg ttttgccagc tcctgtcttc
    61321 ccgctgatca aaaaaagcgg tgcttctgtc aaacgtgaaa aatctacggt ctcattgata
    61381 aaaggaccaa aatttttaag ttgtaatttt ttcggtttca ttcttgatca ttccatttcc
    61441 atgatttctt gcaacgtttc tccgagccat ttttcttggt ttgcagttag ctgctcttcc
    61501 gtcatttcac taaaaaatgc ttctgctaat ttttgaggat ctttcatttc tagtactttt
    61561 cgtttgcgct ttgtttgttc tgctcgaccg tttgcccgtt caatccccaa aatacgagga
    61621 tatatttgcc gaagctggtt catcatattc gggatgatcg ttctatcagt gagatagata
    61681 tagatgtaat tctcccgatt gacggactga taaaaggcag gatccagcaa ttctttgaaa
    61741 ctcgctgtta tttcttcaat atcatgcagg ggttcgatct ccctaaaatt caactccagg
    61801 cctgttgtca ggtcaacgat ccatacgcct tttttttggt tgatctcaga taaagagaat
    61861 ttcaatgggg aaccgctata gcgagcatta tcctgtctca aagcagcttg attatgcaaa
    61921 tgtcctagtg ctacataatc aaacggtgta agtagttcac cagggatcga atccaacccg
    61981 cctacttcga ttttcgtttc cgaatcagat tttacacttc ccattacaaa aaaatggcta
    62041 atcaatactt gttttttttc tgaatcaaat agctcctgca ttttatctat caccttggct
    62101 actgcttgct tgatcgttcg gatattgtca tcttcaaaat ataatctcgc tgcaattggt
    62161 tcaaagtaag gaagaaagaa aaattgtacg tttttaaact cgactggttc aaatgcttct
    62221 gctagctgtg ttcgcaaaaa atagttcgaa taactgaacc atggcgtacc cgctgaaagt
    62281 ctcgtactgc tatcgtgatt tcctgatata gcaaaaatcg ggatcttttc ctttaaattc
    62341 caatcgacca tcaattcatt gtataattct acggcatcaa cagctgggac actcctatca
    62401 tataagtctc cggcaatcac gattgcctct actttttctt ctttcgcgat atctagtata
    62461 gaagatagta catgacgctg gtcttcaatc aagtcataac cttgtagttt ttttccgata
    62521 tgccaatcgg ctgtatgtaa aaaacgcatt caatcacctc aaaaaatgtc cttctaatta
    62581 ttataacact ttgatccatt acatgacacc tgtcttctat tttacatatt ggaacgcaaa
    62641 aagagggcag acttgacgtc tctccctcgt tttcattgaa aaagtctgaa ctgaacagga
    62701 cagtagattc aaaagaccgc ccacgcataa acttatcatt ttattttttt ttgacttcat
    62761 atttgaaatc agggttcact tctttgtcca atttgtcaaa agctgcttgt gttcgtcgtt
    62821 cgatctccgc cataccttct ttatccgttt tcttgatatc tgataagtcg attggttcgc
    62881 cgaaacgcac tgtcactctc tgacgcttga acagatcccc aagtgtcaac ggaccttgat
    62941 atacagctgg cacgattttc gctttagaca ttctggaaat caatgccatt ccgcctttaa
    63001 gttctgtagc atgtcttgtc ccactgggaa acatgatcaa actcaaattt gtcgatttca
    63061 aaatctttac aggtgtttta atgacgcttg gtcctggatt ttctctttta actggaaaag
    63121 cattggatcg agttaatata aatcgcagaa ctggattttt gaacagttct tcttttgcca
    63181 taaagctgaa ttccttgggt gctgcagcta ccgccagata taatgggtcc caccaagtac
    63241 gatggggagc aactagtatg taattctcat cttgcggtaa aacttcttta ttctcatagc
    63301 gggcatttcc attaactaag gctaatagta ctcgaactac cccgcgcata aatcgataaa
    63361 acatagtctc ttcctttccc ttcttatggt catagtatgc ataaaaaata gaggtttgac
    63421 aagccacctt ggttcttttt aataaaaata gtataataca gacgactatt tttttcattt
    63481 tggagggaat ccatgcttca cgaagacgaa cgaatcgacc aattatacgc agaagatatc
    63541 aagattatcc aaagttccaa agtgttttct ttttctttag atgctgtgct gcttgctcac
    63601 ttttcccgtg tacctaaaaa agggaagatt gttgaccttt gtgcaggaaa tggcgcagtt
    63661 ggactttttt taagtaaacg aacccaggcg gctatcgacg ctatcgaact tcaacctcgt
    63721 ctagcagaca tggcaagacg tagtatcgcg cttaaccatt taaatgaaca aatgactgtc
    63781 cacaccatcg atctgaaaga cagcttatct gtcgttcgac ataattcttg tgacttagtc
    63841 gtctgtaatc caccttattt caaagggctg ccaacaaata aaacgaaccc taataaacac
    63901 ctggcaatcg cccgtcatga gattcatacg acgttagaag aagtgatcga tatttcaagt
    63961 aagctactaa aaacaaatgg acgctttact atggtccatc gtcctgatcg gttcttagaa
    64021 atcattcagg tcatggaaga ctatcgaatt gcacctaaaa ggatccaatt tgtttaccca
    64081 aaacctggaa aagaggcaaa tattttgtta gttgaaggaa tcaaagaagg caaattagac
    64141 ggattcaaag tcgctccacc attgatcact tacaatatgg atggagaata cactgcagag
    64201 attcgtgaga tgctctatgg caaatgaaca ttatttttac gtattattct gtaaagatca
    64261 gacattttat ggtggatata caaccgatct ttctagacga ttagaggaac ataacaatgg
    64321 tactggtgct aaatatactc gtcttcaaaa aagaagacct gttaagatga tccatgcaga
    64381 agtattttct tcaagaagcg aagcaacaaa agcagaagct gcattcaaaa aactcacccg
    64441 aaaacaaaaa gaacgttatt tacagacaca ctcaaccgtt ttgcttcctg aatctatatg
    64501 aatgttaaaa acacggtaaa tataaaaaaa cttcaggcaa aaacaaatgt ttttgcctga
    64561 agttttttgt agctatcatt ctgtcacgtt tgtctcactg ctgttcgtac ttgaacttcc
    64621 tcctagcaag gcttcgctga ctaagtgaat gtaatgtgtc atcccttcag gatttggatg
    64681 gacttgatca tcataaaacc agtcactatg gtcattactg tagctgtacc aatcaatcag
    64741 cgtcatattg tcgtattttt tcgtcatctg ttcaagcatc gcattcacgt cattttgcca
    64801 gcgcttcgtc ggtactcgga cattgaccca gtatactttt cgatcaccga ttgcatccat
    64861 cacactatca aactgagctt ccgagaatga gccattcgtt cctagtccaa tcagaacagt
    64921 gtctttcaac aaatcttgtt cctttaattt ttcaatgtac ggtacactgg catataattg
    64981 tcgtccgaca tctccatcta ccactacttt tggataaagt tcttgtagat ccgttgcagc
    65041 atccaacata actgaatcac caaatgccgt tagttctaat ttttgtgcct tattcccttg
    65101 tgccttggac aactcgtact tatcaaggat cgcttggtca accgaactag tggtgttttc
    65161 tgaattgttt ctggtttctt ctgctaattt tttactttca gcgatttttg cctgcagttg
    65221 tttttgatcg gctgttacag cgtttttcgg tgccgtaacg aaaccaacga gtgcaattgc
    65281 tacaagtaat gtgcctggaa caacccatgg tttgctctta ctgatgatcg gtttgctgaa
    65341 ccatcctttc atcacttgga atgtacgacc ataatcaaaa cgtgctagcg gacgctccac
    65401 atatcgataa gaaagttcac tgatgattag aatcaatgtg atttccacta aagtatgcaa
    65461 caaaacatga tcggcaatat cagtcacctt tgcttcataa aaaatcataa ctggaaactg
    65521 atacagataa atgccatagc ttcgtttgcc aatccaagta aatactggat ttgtcagcca
    65581 tcgattcaaa cttgctccgg ggtgtgctgt cactgcaact agcactacgc ataacagact
    65641 cactaggagc attcctccgt aatagatgaa attgtaatga tcatctaaaa agaagaagca
    65701 aagaatcagt gccaaaagcg agattcctcc agcgatattc agaatatttt tcgcttgttt
    65761 cgggatgttt ttctttaaac gcgtacttgg ccaaacaaac gcaagcgcac ttcccaacca
    65821 tatagaaaac agacgagtgt cggtaccgta ataaacacgg gttggatcgc ctcctggtgt
    65881 atacaagatc atcatcaaga tggcggagag gaaggatgta cctaacacag tataaaagat
    65941 ccattttctt ttacgaacaa ataccatcaa caatacaaac aagatcggcc aaaccaaata
    66001 gttttgacct tctactgcta aagaccagat atgcgtaaac ggtgactcat tagcaaatcg
    66061 atcgaaataa gataaaccgt tattgatttg ccaccagttg ttgacataca gtaagctgct
    66121 gaccacaact cctcgaagat tgtttaacag ccctcgctga aacaaagtga tataagccga
    66181 agctgtcaca agcataaaaa caagtgccgg atagagtctc ttcattcttc tgacataaaa
    66241 ttgccaaata ttgatttttc cattttgttc ccattcctgc cgcagcagat ccgtgatcaa
    66301 ataaccagat acgacgaaaa aaatcggaac gcccaaatag ccgcctttca tactagttgg
    66361 cagaaggtga tagaagataa cacccaccac agctaatgaa cggagcccat caaacccagt
    66421 gatgtagcgg ctgtttttta accttttttg tttttccatt caatattcca acttttcata
    66481 aacttttttc attcgtaata tacgggtatt aagtgaaaat agcaagtaga atcgtgtcct
    66541 ttctctacta tttttttcta tcatcccata aatttaaaaa aataaacatg ctttttttca
    66601 actttaagaa aatttcaaat aaaaaagcag tttttctttg ctgattctac tatggtagaa
    66661 aaaaactgca gacaaacgaa cgtctgtcta cagcagtatt tcatgaattt ttgtcaaact
    66721 cgatctaaat gccatcctca tagaaacgac caagtatctg gacgttttct gcaatactta
    66781 caaaagcttg tggatcagaa gctttcattg cttctctaag tagaggcagt tcgtatcgtg
    66841 taacgatcgt catcaatact gtctgcttat catgcttata agcaccttct gcttcattga
    66901 tgatcgtgat ccctctacgc atacagtttt ggatttcatt tactactttt tctggatgtt
    66961 tcgttacgat cattacctgc atcttctttt gtttagtata aacgacatca gttacttttc
    67021 cactgacgaa aatagacaac gtactgtaaa acatatattg ccagccaaat agaattccgg
    67081 caacaaaaac gatcaatgca ttgaagtaga tcgaaataga accaatcgac tttcctgttt
    67141 ttttacgaat cgtgatactc acgatatcta gaccgcccga tgataggccg tttctcaacg
    67201 ctagcccaat acctagtccc atcacagccc ccccaaacaa cgcacagatg attggatcgg
    67261 tagataggac tgtttccggt aaaatatgga tacaaaggga ggtcaaagtg actgtgataa
    67321 aagtgaaaat tgtaaacttc ttcccgattt ttaaccacgc caatacaaac aaaggtatat
    67381 tcagtaaata caaagttgtt gataccggta cttcgaatcc tatcagtgat tttgacaaag
    67441 tcgtcaaaat ctgagctaga ccagtaatac cacttgaata aatatgtcct ggctgataaa
    67501 agaaattcaa tgcgactgat gcgatcaacg cataaacgat agataccgaa agcttggtcg
    67561 tgtaatcatg ataagcccaa ttttcgaatg tttttttcat ggaaaagccc cgctttatat
    67621 gttatggctt cattataaag tgtttttcaa ttaaatcaag gttgtcaaaa gaagcgtatt
    67681 cgacaaatcc tttttacctt tttatcggct attcttctat attcgttaca tcaatattca
    67741 attcgaacaa ttgtaaaggc gaaaccatac ttggtgcatc actcatcaca tctgctgctt
    67801 ttccgttttt aggaaaggca atgacttcac gaatattatc ttctccggct aataacattg
    67861 caaaacggtc caatcctaat gcaataccgc catgtggagg gaatccgtaa tctaaagctg
    67921 ttaacaagaa accaaattgt tcttccattt gttcttttgt aaagcctaga gtttctagta
    67981 ctttttcttg aagctcacga gtatgaatac ggatagaacc tccgcctagt tcataaccgt
    68041 tcaagacgat atcataagct tctgcataga cttttgcagg gtcttcagcc aataacggga
    68101 tatcttcttc ttttggcatc gtgaatggat ggtgagcaga gacatatcga ccttcttctt
    68161 ctgaaaattc aaattgtggc caatcagtta cccataagaa attgaatttc gattcatcaa
    68221 ttagtcctaa ttcttttcct aaacgtgtcc ggatagcacc taatgcagca gcgacgattt
    68281 cacttttatc tgcgccaaac atcagcaagt cacctggttt tgcatctgtt gctttaatga
    68341 ttgcttctgt tgcttctccc atgaatttag caattggacc tttcaatccg tcttcttcta
    68401 ctttcagcca tgcaagcccc ttagctccga attgtcctac atattgacct aactgatcca
    68461 tgtcttttcg tgagtagcga tctgcagcgc ctttagcatt caatgctttc acgacaccgc
    68521 cgttttcaag agccatttgg aagactttga attctacttc tttgactgta tcgcttagat
    68581 cgatcaattc catatcaaaa cgtgtatccg gtttgtcgct gccgtagcga gccattgctt
    68641 catcataggt catacgagga aatggcaatg tgacttcgat accgcgaact tctttcatta
    68701 ccttcgcaat caatccctct gtgtaagttt ggatttcttc tgctgttaag aacgttgttt
    68761 caatatctac ttgcgtaaat tcaggctgac ggtctccacg taaatcttca tcgcggaaac
    68821 aacgaacgat ttgataataa cggtcgaatc cagcattcat cagcaattgt ttaaacaatt
    68881 gaggagattg cggcaacgca tagaaatgtc cagcatggac acgtgaagga actaggtagt
    68941 ctcttgcgcc ttctggtgta gatttcccta ggtaaggtgt ttcgatatcg agaaagtcat
    69001 tatcatctaa ataatgacga atcgcttttg ttgtcgcatt tcttaatttg atgtttttag
    69061 tcatttttgg acgacgcaga tccaaataac gatatttcaa acgtatttcg tcactgattg
    69121 cttgatcatc ttcaatttga aatggcgggg tttttgcttg attcaaaatc acgatttcac
    69181 ttgcaatcac ttcgaattca ccagtggcca ttttaggatt tactgcattt tctccgcgtc
    69241 ttctaacttc cccagtcact tcgatcacgt attcactgcg acatttatcc gcgatttccc
    69301 atgcttcttt gttgatttca ggattaaaga cgatttgaac gattccttca cgatcacgta
    69361 ggtcgataaa gattactccc ccaaggtctc gtcttttttg tacccatcct tttaatgtaa
    69421 ctgtttgttc taattgttgt tcggaaacta atccgcaata gatcgttctt tgtgccattt
    69481 atttttttcc tcctactcga ataaagtcat ttcatcatag acttcatcaa aatgttcata
    69541 tatctcttct aatggaaaac ttttttcttt tcggcttgcc attgctttga cattaatcgt
    69601 ttgactagca agctcatctt caccgatcac caatactaat ttggcattcg ctttatctgc
    69661 tgtcttaaat tgcgcttttg ctttacggtt catgaagtcg cggtcagctg aaaaaccaaa
    69721 gtttcgaatc gcttggacca ctttcaatgc ttcgatattt gtttcgtctc cgagtgcgac
    69781 cacgtaagca tccaactcat taaatgcagg gataactact tcctctgcct ccatagtcaa
    69841 gagtaatcgc tcgataccca ttgcaaatcc gaagccaggt gttgaaggac cacctagttc
    69901 ttccactaga ttgtcataac gtccgcctgc gcaaatcgtt gcttgtgccc ccatttttgg
    69961 tgcgtcactc atgatttcaa aaatcgtatg tgtgtaataa tctagtccgc gaaccatatt
    70021 actgtcgatt tcataaggaa cagccaatgc atccagcatg gaaacaacgg tatcaaaatg
    70081 tttttgagca ggctcgctta gataatctaa gatagatgga gcttctgcca caaatttttg
    70141 atctcgtttg tctttactgt ccaatacgcg taatggattt tcatgaaggc ggcgtttaga
    70201 gtcttcactc agctctgatt caaaaggtaa aagatagtcg atcaatgctt gacgataggc
    70261 ttgacgcgtt tctttatcac ctaatgaatt gatgactagc cggatttgcg tgatccccaa
    70321 ctgtttgaag aaatcaagtg ccatcaccat gctctccaca tcagttgcag ggttttctga
    70381 tccaaatgct tctactccga tttgatggaa ttgacgtaac cgtccttttt gagggcgttc
    70441 gtagcgaaac attggtccca tataaaaagt tttgaacggt ttcgcatact ctgggccgaa
    70501 caatttatgc tcaacaaaag aacgaacgat tggtgctgta ccttctggtc gaagcgtcac
    70561 atggcgttcc cctttgtcat aaaaatcata catctctttt gaaacgatat ccgttgtatc
    70621 ccctacactt cgggatatca cttcatagtg ttcaaaaatc ggtgtacgca tttcattata
    70681 ctgataatct ctgaataata aacgtgctgt ttcttcgaca aactgccatt tttctgattc
    70741 gcctggcaaa atatcatttg ttccttttgg tctttggaaa ctcatagttt tctctccctt
    70801 tcttagctat gtaaataaaa aaatcaccct tgttcatcat gaacaagggt gaatgaaatt
    70861 catacacggt accacctaat tttgaaagat ttctctttcc tcttacgaat aacgctcgta
    70921 cgcgggacgg cttttcactc gtccatctcc agagtgtctt taggctaatg aaactttaga
    70981 tcattttcag cctcgatgat cctctcttgt aaagtttcaa aaacttactc gctctttcat
    71041 tgacattcga tattacttat aacctactaa aaaccagtct caaagtcaag agatatctga
    71101 ctatttcccc tcacaaaaac gttttagttc agctttttgg tattttgttt tagactagac
    71161 aaaaaggagg aatcagctat ggcagaaata agaatcggac attcacaagt ctacgcagaa
    71221 cagcttggat taggagcaaa tgccgttgga ggacataatc tttttgacgg tttggaagat
    71281 gagacaggaa aacaagtagt tcgtacagct ttgaatagcg ggatcaattt gatcgatacc
    71341 gcttatgctt acggaaacgg ccgttccgaa gaactgattg gcgaggtact gaaggaaaaa
    71401 gaatatgatc gctcacgtgt cgtcatcgct acaaaagctg ctcatgtacc aaataaaggg
    71461 cgaacatttg ataattctcc tgagtttctc aaacaatcgg tggaagatgc actaaaacgt
    71521 ctgcaaactg attacatcga cattttttat atccactttc cggatgaaag cacaccaaaa
    71581 aatgaatcag ttgctacatt gcacgaatta aaagaagcag gaaaaatccg agcagtcggt
    71641 gtgtcaaact tcacgttaga acaattgaaa gaagcgaatg cagatggata tgtcgatgta
    71701 gtagaagata aatacagttt gatccatcgg caggctgaaa aagaattatt cccttatctt
    71761 gaaaaaaaca aaatcagttt tgttccctat tttcctcttg cttccggttt gctgacagga
    71821 aaatatgaac ttggtgagga aaaacaattt ggtgaaggag atcctcgaaa aagaaatcca
    71881 gatttccaag gagaacgttt cagagaaatt ttaaccgctg tcgatgtact tcgccccatt
    71941 gctaaaagat accaagccac tcctgcgcaa cttgttttag cttggtacat gaagaatcca
    72001 cgagtgtctg tagttatacc tggagctaag cgtccagagc aagtatctga caatgtccaa
    72061 gctttagatt tgcatttatc caatgaagat tatcaaacca ttgatgaagc atttcgtgga
    72121 ttttgatcaa ttgaccttat caatttatag taatatgaaa aaaggaagat cagcactgtt
    72181 tgatcttcct ttttttcgat aagtttatgc taatctaatt cttgtaaagt agcgctcggc
    72241 tattcggata agtcggaaac tgattgaatg gaatcgtcca atcttgttca ggtacagaga
    72301 actcaaactt atttactagc tgatcggaaa acacacgtag actatgaaga gtgatccatt
    72361 ctcctgcaca gcgatgcatt tgtcgaaaat ttcccccgcc ttgtgcaatc atctcatatt
    72421 cttctttata ggaaatatct tttgctttcc ctacataccg tttgatcata aaggaatctg
    72481 gcgcttcaac tgttcgttca tcatggtctg ttccatataa atctaaaata acccaactgc
    72541 cttctggtat acgataacca tctacttcta cttctttcag cgaaatcgca ggtagcattg
    72601 ggaagaaagg ataatagcgt ctcatttctt gaataaacgg atcttgtaac gtcgaaaagt
    72661 cattttttaa ttgctgatac aaatctggtc tactgaaaag tgcatgtccc atcaatgccg
    72721 cccacacagt tagagcaacc gttggacgga tgatgttcaa taattcaaca gctgccactt
    72781 ccagaggtaa aagctgacca tctaaatctg tggcattggc aaaagcatat aatgccacat
    72841 tttcttttcc agccacagga ttttgtcgag cttcttcaat caagccttgc gcccattttt
    72901 ctgatttttt gcgattttcg acacctttta tgtgatcaat cggagaagta aacgttccgc
    72961 tgatcataga gatttgatat tctgctaatt tttcgacctc atctttagaa atcgctgata
    73021 aattgatacc tgcccactcg caaatagatg taaagaaaac catcttactt aaatcaaata
    73081 gttcaaattg accatgctgt gcttcaagtg cttgtgtcag attcttatct aagatacgat
    73141 gataatcttc cattctttcc ggtgtcatta gatccataaa aatatttttc cgatggtgat
    73201 gagcagctcc atccaaagtc tgtactccac cttgaccaaa aagtgtcttc aatactaatt
    73261 ttggcatagc accttttcgt ttgaaattcc ttggatcata aaatactttt gctgctgatg
    73321 atccgtagat cgtgatagct tctttattga aaatctttgc tttgacgacg ggagcgtccg
    73381 cttcatggcg taactcctcc aacatgttgt atcctttttg atacaatttt tttaaatctg
    73441 tgattttgat atctactact ggtacttctt tcatcttcag caacctccta taaaaaataa
    73501 cttgtataat ttaagcttaa ctttttttcc gactgctgac aaaagaagcg ctttttgcag
    73561 acaaaaaagc cacttaagtt agagtttatc agtctaactt aagcgacgtg tttcatagtt
    73621 tttactagtg aaaaccagat tactttattt gtttttagaa tcaataatga tcgttacagg
    73681 tccatcattg acgagagaaa ccgacatatc tgctccgaat tgtccggtag cgactgtgat
    73741 gccgcgactt ctgattcctt cattgaatga ttcgtataaa ggaatagctg tttctggtcg
    73801 tgcggcttcc acaaagcttg gtcgatttcc ttttttcgta tccgcaaaca gtgtgaattg
    73861 agagatactt aaaatttgtc ctcccacatc ttctacacta atattcattt ttccttgttc
    73921 atcttcaaaa atacgcattt gtgcaatttt ttttaccaga tagtccacat ctttttgcgt
    73981 atcggtttca tgaatgccta ataaaacaag taggccgtag ccaatttttc caatttcttg
    74041 ctgatcgact gacacagcag ctttacttac ccgttgaaca actgctctca tatctgtcct
    74101 cctatccatt cgtccggcgt acactgtaga catcaggtac tgctttgatt ttatccacga
    74161 tactctttag gtgggataaa ttctggatac caaccgtcaa atggatcgtc gccattttat
    74221 ctttattcgt ccgtgcttca acgctgttga gatttttcgt tagcgcattg actgtttgaa
    74281 gtacatcatt caataagcct gaacgattat agccgtaaat ttccaaatct gcatcatact
    74341 cttttcgtgt attcgatgta tcttcccatt cgacttcaat caaacgttct gctacatttg
    74401 gtttgtcagg ctgaacattc ggacaatctc gacgatgaat ggatatccct ctgcctttag
    74461 tgatataacc aacgatatca tcaccaggaa tcggattaca gcagcgactg atacgaatta
    74521 gtaagttttc taccccttga atgacaacgc caccttcatg acgtactttc attttgtcag
    74581 gttctttttt cggctgattc atgatttctt ctgcttcttg cttttgctgc tcgatttttt
    74641 gttctttacg ttctttttca gtcagacgat tggccatcgt caaggggcta acttctccat
    74701 accctacagc tgcatagaga tcatcttctg tttgataatt aaaacgatcg agtgcttctt
    74761 gcagtttgtt cttcgtcaaa atatctttag gcgtaaatcc tagatctgta atacatttga
    74821 ccacggattc gtggcctttg atcacatttt cttctcgatc ttgggctttg aagaaacgtt
    74881 tgatcttatt tcttgctttg ctagtagcaa ctaatttcaa ccagtcgcga cttgggccaa
    74941 atgaatttgg agaagtcatg atctcaatga tatctccgtt tttcaatttg taatcaagct
    75001 gcaccatttt gccatttact tttgcaccag tggttttgtt accgatatct gtatggatac
    75061 tgtatgcaaa gtccaatggt ccggatcctt ttggtaactc agtaacgtct ccttttggtg
    75121 tgaagacgta gactttatca ctaaagatat ctccttttac gccttccata aattcagaag
    75181 catcatagct ttcgtcttga agttcgagta tctcatggaa ccagcttaat tgtttcgtca
    75241 taccatctgg ttctactttt tcattttttc cttctttata ggcccagtgt gcagcaaccc
    75301 cgaattcagc gatttcatgc atttcctgtg ttcggatttg aatttctacc ggatttcctg
    75361 ccggaccgat cacggtagta tgcaaagatt ggtacatatt agcttttggc atggcaatat
    75421 aatccttaaa tctgccgggc attggtttcc attttgtgtg gattgctcct aatacagcat
    75481 aacaatcctt gattgaatct acgatcactc gaatagctag caagtcataa atttcgttga
    75541 actgcttttt ctgatctttc attttacgat agattgaata aatgtgtttt ggccgtccat
    75601 agatttctgc aaaaatcccc agctcttctg tcgctattcg aatatcttca acagtaccac
    75661 ttacgtattt ttcacgttct tctctcttcg tctgcatcaa gtggacgata cggtaatact
    75721 gttttggatt tagataacga agtgctgtat cttctaattc ccatttgatc cggctgatcc
    75781 ctagacgatg tgcaagaggc gcatagattt ctaaagtttc ctgagcgatc cttctttgct
    75841 tatcttctcg caggtgcttc aacgtacgca tgttatgtag tctatcagct aatttgacca
    75901 tgataactcg taaatcttga gccattgcta gcagcatctt tcggtggttt tctgctagct
    75961 gctcttcgtg ggatttatat tttattttcc ctaatttggt tacgccgtcc actaacatag
    76021 caacgtcatc gccaaattct tctctcagat cttctaaagt gatttctgta tcttcaacaa
    76081 catcatgtaa gaagcctgta gccactgtat ggggatccat ttttaaatct gctaatatac
    76141 ctgcgacttg gataggatga ataatgtagg gttcgcctga ttttctaaac tgtccgtcat
    76201 gtgcagcagt cgcgtattcg catgctttct caacaaatgc tacatgttcg ggacccatgt
    76261 attgactaac gagctttatg acaccgggtc ccgttaaaat ttcttctttt gtcacaggaa
    76321 tcgatccccc tttctttttt cggtaaaacg ggaatcggga caaatatctg tttgataatt
    76381 gtcccaaaat ccgtgcagtt atacgttttt ttacggaaat gttcgctttt taaaagcttt
    76441 ttcaaacgat ttttcgtatc cattgtataa ataattgttt ctattataca aattgttgac
    76501 tattttttca attctttctg tcgatactct tttattaatg aagaacgtta gctaaaagaa
    76561 ggattcatta attcccattg atagctagca gcacttaata aataaagagg tgctgtttct
    76621 gtacgaagga ttcttggtcc taatccacaa agtatccctt tgtgttctac aaaataatcg
    76681 acttcatcgc gggataatcc accttctggt ccaaagacag ctaagattcg actatctggt
    76741 tttgtttcac taagaatttt ggctgcattt gatttttcgc cttgctttgc tgattcctca
    76801 taagcaacca agaccacgtc ataatcatct agccgctcaa ataaatcttg tttcgtttcc
    76861 aataactcta ctgatggcac gatctgccga tgggattgtt ccgctgcctc ttgagcaatc
    76921 ttttcaagcc gttgttgtcg tttcatacgt ttttttgcat cccatttaac gacagaggct
    76981 gatgccggga aaccaagaaa agcttgcgct cctaattcag tggatttctg aacgatccaa
    77041 tccagctttt cccctttagg atagccactc gctatggtaa tcgaacttgg cagttccttt
    77101 tgattttctt cttttttaat ttctttcaga taaacagcct cttcagtaat ctccgtgatt
    77161 tctgcaacaa tggctatttg atcattgaat gccaaaaaaa cttcatcctc gggttccatc
    77221 ctcataaccc gtacaatgtg gtgatagttt tccccttcta aaacaaaata gtcttttgat
    77281 tcatatgatt cttttaaaaa ataccgctgc atctattcca cctctggttt tttcaaaata
    77341 attgcatacc agtctttttg ctggaaaatt tgatccacga taaacccttg ttctaacatg
    77401 gcatccagaa ccatttgctt cttctcttca atgattcctg aaacgatcag cgtgcctgtt
    77461 tgcttcagta aacgccaagc atctgggatc atcaataaga tgatatctgc taaaatgttc
    77521 gcaacgatta catcactttc aatctcgatt cctgtcaaaa gatcgttagc tgatacatgg
    77581 acatctttgg ctatttcatt catatccata ttttctttcg ccgaacgaac ggctacttcg
    77641 tctaaatcaa aggcatagac atcttttgca ccaagatatt ttgctgcaat acttagcacg
    77701 cccgacccag ttcccacatc tagcaatgtt tcaccaccac gcaagactgt ttctagtgct
    77761 gtcaatgtca aggaagtcgt gggatgagtg cctgtgccaa atgccatacc aggatctagt
    77821 gtgataattt tttctagagg atcttctgtc tggtagtttt cccagcttgg cgcaaccgtc
    77881 agcattcgcg taatacgcac cggatgatag tatttcttcc aggctgttgc ccagttgctt
    77941 tcctctactt cactaactgt tactttattt tttccaatag ctagaccaaa ctcaggtaat
    78001 tgtgtgatac gatctttgat aaaaggcaag atttccggta agaaagtcgt ttccggaaaa
    78061 taagccatga ctagtgcgcc ttctttcagc gatgtaaaat catttttatc taaaatctca
    78121 ccatattgat ccgactgaaa atgttcaaca tctaaagaat cttcaatcgc gacaccactc
    78181 gcccctgcct ccatcaaaat attagcaact gcttcgactg cttcactttc agtttctact
    78241 tttacttcat tccatttcat atctgtcact ccttaataac ttgggtacgg taaataagta
    78301 tctgcttcat tttgctgttt tacttctact aattctgcta gttgctgatt atcccagtga
    78361 agctcgaata cagcttcgtc atcgtcttca tccaaaaaat caagcaaatc gctttgccct
    78421 tgagctaata cttcatttag atattccact aaagaatcag ctactgattt tgccaaccct
    78481 ttttttcctt cataagggat tactgctaga taattgcgtt catcaaaaac agatttctga
    78541 ggattaaaaa gaagtacgcc gtcttcaaat tcgataattg gttcttgcga aacgatccct
    78601 tctgcatcat caatctcaaa ttgtgcttta ttttctgcaa acaagcgaac aacgatctcg
    78661 atcgtatgat tttttgtatc ccaatctaaa gctacatcat agtctgtcac ttgtttttca
    78721 attatttcat ctaaatatgt taatagatcc ttctttttca ttttctttcc tccaacccca
    78781 atctttctcg atttggtttt ttctttgtaa agagatataa ggatttcccg acacaacaaa
    78841 acgcaacggc ttttctgtcc atacaccttt gtttgggata ccgattctag gcaaagcatt
    78901 gatctttttt ggtgtctttt ttttctcaaa aactaagcgt aacgaactat ctgctataga
    78961 ctgaccataa agttcttgag gaattgctaa tgcttccact aattttcccg gaccgttgct
    79021 gatatctgga ccagtttttc cgccacgatt tttactcatt tgatcaatca ttgcggcggg
    79081 ttcgattgca cgtatcatta ctccttgagg aatcccttct ggctgagtaa tgatgttcaa
    79141 aatccgatga gtatgcatcg tgtaaaggta gatcgtacct ggtttttcat acattgcccg
    79201 cacacgcggt gttcttctta aaccatagct atgggcggcc tcgtcttctg gacctaggta
    79261 tgcttccgcg tctacaatat atccagctaa tcttccttct ggtgtgtcat gctccaaata
    79321 catccccaat aaatcccgtg ccacttctgg cgtcgtttta ttccaaaaaa attcatctat
    79381 cttttgttta tccgtcattt ttctcaccta ctttatcata cacaatatta gttggataag
    79441 ctatgaaaac aaaacaacag aaggctgttc tttctaggca tcttgctaaa tatgatataa
    79501 ttaagggacg taaaaacaag aaggaggaaa atcctatgca acagccattg gcttatcgca
    79561 tgagacctcg aacgatcgat gaagtcgttg gtcagcagca tctagtcggg gaaggaaaaa
    79621 tcatacgccg catggtcgat gctcgcatgc tctcttccat gattctatat ggacctcctg
    79681 gtactggaaa aacgagtatc gcaagtgcga tcgccggctc tactaattat gcatttcgca
    79741 tgctaaacgc cgctacagat tcaaaaaagg atctacaagt tgtagcggaa gaagcaaaaa
    79801 tgagtggtac agtgatcctc ttattggatg aagtacaccg attagataaa acaaaacagg
    79861 attttctgct tcctcattta gaaagtggcc gaatcatctt gatcggagcg actactgaga
    79921 atccttatat taccatcaat ccagcgatcc gcagccgtac acagatcttt gaagtcaaac
    79981 cattaacaga acaagacatc cagttggcag tcgaacatgc tttaagggat aaagaacgcg
    80041 gccttggaca acaagcaatc cagttagacg aagatgctct tcttcacctt tcgcgtgcaa
    80101 cgaacggcga tttgcggagt gcattgaatg ggctggaact ggctacacta tcgactcctt
    80161 cagataaaga aggaaggatt catcttacac tgtcgatcat tgaagaatgt gtccaaagaa
    80221 aagctcttac ccatgacaaa aatggagatg ctcattatga cgttatttcg gcttttcaaa
    80281 aatcgattcg tggaagtgat gtggatgctg cacttcatta tctcgcccgt ttagttgagg
    80341 caggtgatct ggcaagtatt tgccggcgtc tgatggttat cggttatgaa gatataggtt
    80401 taggtaatcc tgctgctgcg gctcgtacag tgaacgctgt attagctgct gaaaaattgg
    80461 gattgcctga ggcacgtatc ccactagcag acgtcgtcgt cgatctttgc ttgtcgccaa
    80521 aatccaattc tgcctacatg gcattagatg cagcacttgc tgatattcga gagggcaaag
    80581 ctggagatgt tcctgatcat ttgagagata gccattacaa aggtgcgaaa tcactcaacc
    80641 gtggcgtggg ttatcagtat cctcatcatt ttgatcaggc ttgggtcaat cagcaatatt
    80701 taccagataa actgaagaat gctcagtatt atcagccaaa agatacaggg aaatatgaac
    80761 aggctctggg tcaacagtat taccgtataa aagagtggaa aaagcatcct ccaaaaaact
    80821 agacaagaaa acggttctgt ttctgcgagc tctctcattg ctctttttaa attcatatgc
    80881 tactatagag gtgggaaatc tgtgatgttc gaattgtcct ctttgtgtgt tgaccgaaca
    80941 tttttattga tatcttggga cccgtcttgt gtcactgctg gtaacatgcc ttatcatttg
    81001 gtagttcgaa gctacgacca tgggacccac ctgcttgaat tcgcgggatc aatactacag
    81061 gacaaacaac ggcattaacg gagattacca tcttttaaag aataaagcaa tttgctcttg
    81121 gcaaattgct ttttctattt gttgcttatt ttggaggatt tgttcatgat taggatttta
    81181 atgattatcg ccactttagt attattattc gttagctatt atttatttaa taaacaggat
    81241 atcttttttg tattgatcaa caaaaatgat aaaaatcaag gattcctaca attttacggt
    81301 gctgcatatg ctgttttagg cgtaatgggt attttaacag cttttttcaa tcaacgcttt
    81361 attgccttgg tctttttact gatcgtaatt attgtttctg ccaccttcag tatccgattt
    81421 gcaaaaaaaa ttgctgaacc aaagcagtaa ataattctct ttttccctaa agtgttctac
    81481 aataaaagag tacaatacga ttgacttgag gagtgaatgc ttatgttaca acaatacaaa
    81541 aaaatcatgg ttgccgtaga tggttctgat gaagctgaat tagcttttaa aaaggcggtc
    81601 aatgtagcta tccgaaataa cggagaactt ctattagcac atgtcattga cacacgttct
    81661 ttccaaaccg tttcatcctt tgatggaatg cttgcagaac aagctactga aatggcaaag
    81721 caaacattgg cagattatga aagcaatgcg aagaaagctg gcttgaataa tgtaacctct
    81781 gtcgtagaat atggctcacc aaaacaaatt attgccagag aaatcccaga agataatcaa
    81841 gtagatttga ttatgttagg agccacagga ttgaatgctg tagaacgttt atttattggt
    81901 tctgtttctg aatatgttat tagaaacgca gcttgcgatg tgcttgttgt ccgaactgat
    81961 ttagaaaacc aattgccagc taaagaccac accaaagctt aacacgtaga cgacctgcca
    82021 actatcggca ggtttttttg cacaaaaaac cgtgataaaa acaaaagacg cggcaagcac
    82081 tcatcggtct ttataatgtt taaaataaag ggaaaacagt caatgagttc aagtaaaata
    82141 aaaaaaagtg aacaccaggg cgattagtcg ccctggtgtg gtttaaaacg acctaagcat
    82201 gccaaagctt attggttcgt caatgtggaa gtttccgatg aatctgatac gaaaaaatat
    82261 gaagtatcga tggcggatac cgattttatc gccaaactaa aattttattt cgggttcggg
    82321 taccgcgaga aggcaagtgc tacattcggt aaatcattca agaattgatg aaaggctacc
    82381 gcttgccatt gcaaccacaa cgatactcct gaacgcgatg ttggtgagat ttccaaagag
    82441 aagagctgtt taatgcaacg gtattaagca aatggcaaaa ggaagtcatg tagacaaagt
    82501 tttttatcaa acaccatatg atttcgcctg aacgctggtt tagctcagaa tacaatgatg
    82561 tggtccacga gacattaccc tcagtcagat aaaaaaagct ctctgacaga attacacatc
    82621 gataaatatt aagtaaatgt cagcgctagt tgaactttct gacactttca ggtacactgg
    82681 aaaagacaac tacacgaagg agggaaaata ctatgatgcg catgactaaa ataacaagta
    82741 atgaaaatta ccaacgatac catatcgcat ttagccatgc aattggtttt acagttgctg
    82801 ttgacgggac aagtttatcc aaaacagttg aattcacgta aaatcaatgg ccatctcaag
    82861 gtatttttct catgataatc tgagtttaaa taacacaggc catggataac catggccttt
    82921 ttgagtggtc tcaaggagag agatcatgat catacaagca atttctatta aaaaaacaat
    82981 cggcgggaat ccattatttg aggatttatc ctgtcaaatt gaagctggtg aaaaaattgc
    83041 cttagtcggt atcaacggaa ctggcaaatc aaccttttta caaatcttga ccggcagaga
    83101 aggtgtcgac agcggtgtta tcagtcgcaa aaaaggctta aagatcggga cggtcgaaca
    83161 agaacttaca gtttccgaag cgaccgtcaa ccactacttg ctccattctg ccgctgagat
    83221 acaggacctc aaacagcaaa tgagtcgcta cgaagcattg atgacagaac cagatacaaa
    83281 cttagagaag tgtctggccc gttacggtga gctgcagcat cgctttgaag aactaggcgg
    83341 ttacgtatta gaagaccgga ttgcagcgat cttgcaaggc ttagggattc cacaccgtca
    83401 ggaagcacgg ttaacagaac ttagcggagg cgaacgagtt aaagtcgctt tagccaaaat
    83461 tttagcagcc gatgccgatt tacttttact cgatgaaccg accaatcatt tagatcttaa
    83521 cagtattcgc tggttggaaa actatttaca gaatacaaaa aaatcggttc tggtcgtttc
    83581 tcatgatcgg caatttctcg atcaagtcac cacaaaaaca tgggaactgg aagaaggtgc
    83641 attgattgag tatcccggaa actacagccg ttttcgagtc ttgaaagaag ctcgcttggc
    83701 tgagctgaca aaaaattacg aactgcagca aaaagaagtc cagcggttga aagtcatgat
    83761 tcgtcgtttt cgtcagtggg cacatgaagg agacaatgag tccttcttca aaaaagccaa
    83821 agaactggaa cgccgcctgg cgaaactgac actcgtcaaa ccgccacctc ccccgaaaaa
    83881 tcggctgcaa agcttgtcta atggtggaaa atctggcaaa gaagttttca tcattcaaaa
    83941 cttgcaccag cagtacgctg atcaagtact attcaaagac agcagttttg cagtctatcg
    84001 tggagatcat ttagccatca tcggcgacaa tggtgcagga aaatcaacct tactcaaatt
    84061 attactcggt gaggaaaagc cttacggtgg caccatcaaa ttaggtagta gcttgcaaat
    84121 cggttatttg ccgcagcagc tgcagtttgc cgatcccgat agccgtttgc tggcttacgc
    84181 catcacattg actggaaacg aagaagtcgc tcgacggcaa ttagccaaaa gtggctttta
    84241 tcaaagcgat gtgggtaaac ggatcaaaga tttatccggt ggtgaaaaaa tccgtttggc
    84301 gttgctgaaa ctctttttag aaaaaatcaa cgtcctgatt ttggatgaac caaccaatca
    84361 cctcgacagc tatgctcgag aagaaattga agaaatgctg caagactatc aaggaacgct
    84421 cctagcagtc agccatgacc gctacttttt gcagcaacac ttccaagaag cactcgttat
    84481 tgatcaggag cagatcagcc gccagccgct cggccaactg attgactagg acgttttttc
    84541 gcaacaaaaa acttgatttt catacctgtg ctttcacgat tcaggcaaag tacaggtgga
    84601 aaatcaagtt tttattattc gatcaatgaa tgtttcggat cggttttcta gctaaacata
    84661 aagcgaagaa taaagtcgac agcccacgag gctgatctaa aaatgttttt tctttttaca
    84721 tatgtaatgt cccttataaa gatgaatgaa aataaaatat tgggattttc ctgaaaatca
    84781 ataaataaaa tgccagtctt ttcccttttg accacttttc caagcaaaat tccctaagaa
    84841 gatcctgtaa aaaagaaggg aaattgaagt taaattacca ttttgcggtc ttctccgcaa
    84901 aaaaaacaca tgcaagaatt ccctcttgca tgcgtttcat cttttatcct aacgaatgct
    84961 ttggcttagc cgcgcagacg ctccacatca cgggcaatca ttagttcctc atctgttggg
    85021 atcactaata ctcttacttt tgattctttt gtagagatat ctacttcttc accacgcaat
    85081 tcattcaacg ctggatcgat ttcacaacca aaccaagaca tacctttgat gatttcacta
    85141 cgtacatgtc cgtcattctc gccgatacca gcagtaaaga caattgcatc aacaccattc
    85201 atcgttgtca cataaccgcc gatgtatttt cggatgcggt ccacgaaaat gtcataagct
    85261 aaacgaatat gttctttttc atagttcttt tcaagatcac gcatatcact agacaatcct
    85321 gttaggccta gcagaccaga tttcttgttc aaaacattga tcatttcatc aatatcaatc
    85381 tctaattttt ccattaaata tgggagaaca gctggatcga tatcacctga acgtgtaccc
    85441 attgtcaccc cagctaatgg tgtgaatccc atagaagtat ccatggattt acctccatcg
    85501 actgctgtga tcgatacacc atttcctaag tggcaagtga tgatttttag ttcttcgatc
    85561 ggtttgttca ataattttgc cgcacgttcc gacacataac gatgacttgt gccatggaag
    85621 ccatattttc ttactttgaa atcttcataa taagacaccg gtaagctata taaataattt
    85681 tgctttggca ttgttgagtg gaaagatgta tcgaatacag ccacactcaa aatgtcaggt
    85741 aaaatctttt taaacgcttt gatccccatt aagtttgcag gattatgcaa aggagcaaat
    85801 tctgctaatt cagcaatgcg gtccattact ttctcatcga tcactactga atccccataa
    85861 gtttctcctc cgtgaacaac acggtgccct actccggtga tttcatcata agagcttaaa
    85921 atttgcagtt caatcaactg atctaacagc atttttactg ctacttcgtg gttttcgata
    85981 tccatgattt gttcgaattt ttgattatcg ccgtacttga tggtaaaaat agaatcttgt
    86041 aaaccgatac gttcgacgat ccctttcgca actacggttt cttctggcat ttgatataat
    86101 tgccatttca aacttgaact cccagcattg attgcaattg ttttagacat atgactctcc
    86161 ttctcgttga atgattacag agcagatgat ttccagtttt taaactcgtt gaaaaattcc
    86221 gtcaccttct ctggttcttt taatgaagca agtttcacaa gcaagacttc ttttacttgt
    86281 tgtgcttgtg gtcctttttt ctgtaagatc aaaatacttt tttgcgattg tttattacgg
    86341 aacaattcat ctggcaattg aatcattcct tgaagataac cttcttcttt aaaccatttt
    86401 ttgatttctt cactttgatc cgtttctaaa aatccactcg gcatcaaaaa caaaccaaaa
    86461 ccatccggct tcacatattt cattgattgc tctagcaata aatgatgtgc ataactatgg
    86521 ccttcttcgg tacttgttaa aaactctttt gctttttcgt cattcggata ataaccgatt
    86581 ggcaaatcgc tgattgcaaa atcgacagga tctattaata attcctgcaa cccgtcttga
    86641 tgaaagtatt gaacatttgc ttgtgtcaaa tcacttgtag aagctgcgac agccaacaat
    86701 gtatcatcaa tatccacacc aattccttct gtttggtacc ccgcattcga taggtttaaa
    86761 agaactgtta ataacaagtt gcccattcct gccgcaatat ccagaatctt aaccggtgct
    86821 tttttatttg tgtatagttg ttcaataaga aaaacaaata aaaaaccgat actatcagga
    86881 gtgagttgat ggttcgcctg caaatgttct gtctggctgc ccttcaataa aagtaattga
    86941 gacagtctgc gccattcttc tggctcgaaa gaaagtttct tcaactcttc ataaagagct
    87001 gtgatccgtt gcgttgtctc ttttgtcggc actccatcca ccacacgtac ttgataatca
    87061 tctattaaat tttctgcatt ttcgacatag gcttctaaaa aggaagttcc caatgcattc
    87121 tgtaaaagct gaatagcttc caggttttga ttaaaccctt gttccatttt ttctggtaac
    87181 atggtgcacc tcatttctag atatattata acaatttttt cacctgttta attctatcga
    87241 acaattgaca aaatttcaat cgttttcact gttttttatt tgtgaaacgg caaacatttt
    87301 tttattaaaa acagtgttat aacagaaaag agggcgtttt cacgaacatt ccatcattct
    87361 gtactagtat ctgtatcatt ttttacttct tctgtgaacc gaaagataaa cggtgagact
    87421 tccacctcta agaataggga ctgttgtacc cactgatatg ttacagatcc agttgtgtag
    87481 taaaaaactc cttccgaact ttcggcaagc gtagactgtt ccgataaagc catctgcttc
    87541 attatttttg ctatataata atttttgatt cgtatattaa gatccattga caaacggtag
    87601 ctttctaatg ctgccatcaa taaaaacgta cataaaagaa ataaaagcaa gacagaaaat
    87661 aaaatagagc ccttataaca ttttctactg atcgtttttt gtccatatgg catatccatc
    87721 ttctccattt tcaaagtgta cataaaaaga aattgtgtgt tctttttcca ataattgaag
    87781 ctcagtgata cttgttaaca taggttgatg tccgccggaa gttcttcttt tacgtatcat
    87841 tgcctgatat ctttcgatga tatactgttt atcctcgatc gtgtagtgca gttgctgatt
    87901 tttcacagag acattgtgac tgctcttgag ttcttcttct aattgtgcta aaaatattag
    87961 ccactctttt tgatctttac gctgcaaaaa ttcacttact tggatggttt gctgaatcaa
    88021 aagattgaat gtgagcaata gactgctcaa tatcatcagt ccaattagac attcaatcag
    88081 cgtaaatgct ggaattactt gttttttcaa tactgatcgc ttctttctcc atattgacaa
    88141 acactttttc gattactcca ttattatcga caatttggat atcgtatggg atcatttctt
    88201 cccttcgctc tggtcttttg tgatacatcc gctgcgtctt gatatcttca taaatcattc
    88261 gaataaatag cagttcctcc ccacttttct tttctgcctg aagcaaaaac agctggccaa
    88321 agctcactaa gtagacacag acagaagcga tcataagcgc tgtaagggac tccaacaaaa
    88381 caaatcctgt tttattcaat tctttttgta tagcgaccac tccctatctg gaattgatac
    88441 gtaatcgtcc gctctttttc ttcccaataa aattgataag cttttagtga actttcattc
    88501 ccggttctag cagcaaaagt aatagaagca tggcgtttca aggtaatctc atcaggaata
    88561 tctaatactt cccaatttat tttatctgga ttcggaacat gaaaaatgat ttgattctct
    88621 tcactattcc aataaaagcc tgtttggatc tgattcacaa tagcgatttt ttgcgtagaa
    88681 tagattcgtt tttcaaattg gccgaaaaat tgatagactg ccaattcatt cttccatgca
    88741 gaaaatgcga gaactggaaa agaaaggatc gttgtaagta ataaaatcag taagagtgat
    88801 tcaaacaacg tatatcctga tgctaaaacc ttaccttcaa ggccgctgat agatttctgc
    88861 atgttctcgt ttgatatagc cttcattcaa caattcctcc acagtaggaa ctcttccatt
    88921 attttgaagc gcatagagct ctttttgtgt gtctaccaac tggatgatcg cttcacgact
    88981 ttcttggtct acatgattcc tataacgcga caaattaggg acgaacaaca acactaatac
    89041 actgatgatc agtaagacga ttagcatttc gatcaatgta aaaccgctat aataagatat
    89101 ttttctcttt ttcatggcaa aacctcctct atgcttccgt aaacaggtaa taaaacagcg
    89161 gcataaacta ataaaatcaa agccgctacg cccaaaaaaa tgattggctg aataaaatgc
    89221 atccagtgat gaagacgttt gaaaagctgt tttcttgtcc attcgctgta aaaaatcagt
    89281 tctttaccta aacttccctt tgcctctccc tgtaaaacaa ttttactgaa ttcttctgat
    89341 agaaaacgat aattctggaa ctgctcagcc aatgacatac ctgcctccaa tccttgaatc
    89401 aacttagagg caagatgctg aatcagactt tcttgtttcg tttcctttaa gcagactatg
    89461 atttgcctta attcgaaacc ttcatgaaaa agctttccaa tctctagtga caaataagcc
    89521 gattgataca aggaatatat cggtccaatc aataattgtc tgcttatcca ttcactctga
    89581 tcaacaggag acaacttcat cagacgatac cttactagta aagccaatag agtaaccgct
    89641 aggatgaata gtagaacata ccaatgaaag acttgtatca gctgaatacc ccaatgctct
    89701 tgcatgacca ttcctgaacc aataagctga ggcaaaacga acaaccgcat actaaacaag
    89761 atacctagca aaaaggtgag caatagcatc ggatatgcaa gcagcttttt caaatcattg
    89821 cgaaatcctt caacaagccg aaactgtttg gcaatttcca acaaagttgt cggcagattc
    89881 ccatgacgtt cagctaactc gatctgtacc agttgctctg ctccatatcc tatttgcgaa
    89941 agtacctcac taaacgcttg cccttccttt agctgatgtt ggatatttgc caaaataaca
    90001 ggtggaaacg aacggatcgt gagtaataaa taaagggatt cttgcagact aaaaccagat
    90061 aaaagcagtt ctcccatggt ttgtgcaaac tggttttgct ggcttcttgt taatccttta
    90121 gaatagttct gactgccaaa tattttcctg agcttcttca taactttcct cccatgattt
    90181 ttttactgat tcttcctcca taaattgata actccataaa acagaaggat ggtgattggc
    90241 atcttccaaa agttcttgat aaatgacacc agctaaacat tcagatagct cttctttttt
    90301 ctttgtcagt tcatggattc tgaccaatgt accttcaaga ttgcgtgcat gtacggttgc
    90361 aaaaacccgg tgccctgtta gtgctgctct taccgcagca tgtgcagttg attcatctct
    90421 tatctcgcca atgattagca agtctggacg atgccgtaat gcgagtttca aaagtgtatc
    90481 ataagtctgt gctattttcg gattgatctg tagctgcaga aaaaacggtt cttctatctc
    90541 tacaggatct tcgatagtaa tcacttgcaa tttttcttcc aaagccaacc gatacattag
    90601 agaagtcttg cctgatccga ctggtccgct gaaaaggtat aatccacgtc tgacggtttt
    90661 ctgtaaaata gttgcaaaat ctcgagaact aaagcaacga tggggtgttt caaaagtacc
    90721 gtataatagc cgaatcacta aactctctcg ttgaaggtaa tctcctacag aagacaaccg
    90781 cagacgaact tcctgttttt ctaaagaata agtaaatgca cctaactgag cttttctttt
    90841 ttctccgata tccatctgtc ccaaatactt aaatcttgag atcagttgct gtccatctgc
    90901 cgaagagact ttcttccaga atgttcgttt ttttccatag cgaaaataga tgtaaaatac
    90961 ttctgaagct ggcaatatat atacgtcttg ggcatgtttg gcaaaacttt cacttatcat
    91021 ttgatccgat aatcgtttta tttccattat tctcccctcc acaaaaaaca tacgtctttt
    91081 tgatcttttt gtttcaaata aaatgaattt acaaaaaaat attggcaaaa gccgaattta
    91141 tgttatactt ataaaaattt atcttgggag gcactccatt ggaaacaaca ttaaggaaat
    91201 atatcgaagt agcaagtaaa aaaaagcctg ctgacctagt gatcaagcat gctaagatcg
    91261 tcaacgtctt tacgaaagaa atcatggaaa aagatgtagc aatctgcgaa ggaatgatcg
    91321 taggaatcgg tgaatacgaa ggaaaaagcg tacataatgc taatgggcaa tatctagtgc
    91381 caggattcat cgatggccat gtgcatatcg aaagctcact tttatcacca agcgaatttt
    91441 caaaagtatc cttgcttcat ggagttacta ctgtagtgac agatccccat gaaataggaa
    91501 acattgctgg gagtacaggt cttgagttta tgatagaaga tgcaagacaa acactcatga
    91561 atatcttttt tatgctacct tcttgtgtac ctgtaacccc ttttgagacc aatggtgcaa
    91621 atttaaatgc aaaaaaatta gccccttttt tacaaaaacc cgaagtttta ggcttagctg
    91681 aagtcatgaa ctatcaagca gtagcaaata atgaaacaga catcctagaa aagatccaat
    91741 tgatgcacca gcataagaaa aaaattgacg ggcatgcagc tggtatcggc atggaagagt
    91801 taaatgttta tcctgcagca ggtattcgga cggatcatga agctacaact gcaaaagaag
    91861 ctaaagaacg tttggatctt ggtatgtatt taatggttcg agaagggacc gttgcaaaag
    91921 atctggcatc gctactaccg gcgatcacac ctgaaaattc aagaagatgc ttctttgtca
    91981 ccgatgataa actgatcaat gatttagtaa aagaaggatc aatcgatcat atcgtccgtc
    92041 aagctattgc acttggaatc gatccattac aagccattca gatggcaaca ttgaatgcag
    92101 cagaatgttt tgatttgaaa acactaggtg cgattgcccc tgggtatcaa gctgatttct
    92161 tcttaacaga cgatcttacc aagctgccaa ttcatgaagt tttctataag ggaacattag
    92221 ttgttcaatc tgggcaactc caagaccatt tatttgctga tcattcaaat tcatatacgt
    92281 gttgtctgcc aaaactaaac gctcaaccat taaatccaca ttcgttagag ctgcttcttt
    92341 cttcttcaca agcccatgtg atcgaaatta tcccgaatag tctagtgact aaagatttgg
    92401 tagaaaaagt ggaccgacaa ggcgaacgat tcattccttc aatcgaaaaa gaccaattaa
    92461 agattgcggt gatcgagcgt caccatcaaa cgggaaacat tggattaggc atagtgaaag
    92521 gatttcagct gaaacaagga gcgatagcga caacgattgc ccatgactcg cataatctag
    92581 ttgtcgttgg gacaaacgac gaggatatgc tgtatgctgc taatcttttg attcaaaaag
    92641 gtggcgggat gaccgttgtc aacaaacagc aggaaatagc ttgtgtttct cttcctatag
    92701 gcggaatcat gacacaggaa cctttttcga tcgtctatga acagttgaat gaattaataa
    92761 ctaaagcaca tcaactagga gcagctaaaa cctttgatcc ttttttgaca ctttctttct
    92821 taacattatc tgtcataccc gaattgaaga tcaccgacaa aggattattt tcattttctc
    92881 gcttccaatt gattccacct tgtggaaaaa ccgatgaaat aaatacattt taaatcaaat
    92941 aaatcccaga aaatacatta catctgtaat gttcattttc tgggatttat ttatggatat
    93001 taatgttttt atgaaagcag aaagttagtt tcacagactt ttctttttgg tcttatcttg
    93061 aaattgagct tctactcgat aaatacgttg accttttgaa gaaaattttt cttcatactc
    93121 cgtcataata ttgccttcaa attgactttg atgtaaatct aaccatacct gtttgaggat
    93181 catgccatat tgagaaaaac ttgccagaga atactcaaac aatccttgat tatctgtttt
    93241 gaaatggatt tctccatttg gacgaagaat ctgttcatct acagcaagaa aagtcttata
    93301 tgtcaatcgc cgtttttcat gacgtttttt tggccatgga tcggaaaaat tcagatagat
    93361 ttgatctact tcgctgtcag cgaaatactc tgtcaacgct gatccatcca catgtagaag
    93421 tttcaggtta ggaagcggtt gttcgatcaa cttgtctagt gcaatcgaaa caacactgac
    93481 ctgcatttct actccaatat aattgatttc aggatgggct tttgccattc cagtgatgaa
    93541 ctggcctttc cccataccaa tctcaatgtg gattggatga tcgttttcaa acaattcatt
    93601 ccattttccc ttccacaatg ttggatcact aattacaaaa ttcgggtgag ccgctaacat
    93661 ttccgctgct cccggacgat ttcggacacg cattatttat ctccattcct ttcctctaat
    93721 taaaaaggtc tggccaaatc tccgcagagt ttgggccaaa cctcagccac tgaaaattcg
    93781 ttttaattgt aaaatttctt cgttcatccg tcgatgatct tcacgtttgc aatatctggt
    93841 gatttcttgg agcaaattca tggccgcata ccaatgaaat ttttcaagca tttcgtcagt
    93901 cgggcgtatg ccataactga tcagccactg attccagcta gacagtggca cataatttcc
    93961 taaaatcgtt gcaatatcca ccgcagggtc tgcaaacatg attgaatccc aatcgactag
    94021 atataaataa tttttacata ctaaccaatt acgatggttt acatctccgt gtactactga
    94081 taagttttcc ttatctattg acgggatctg ctcacgaaga aaacgatgga caatttgcag
    94141 aaattgattt ttctggagtt cttccggtaa ttctttttca tatttttgca gcatcttctc
    94201 cggcgtcatg acacgaccac cgatacgggt cagcatggtt ttaagagaat ttgaatgatg
    94261 taaatggtac aaaacatcaa tcacgtcgtt tctttgacca atctcattag gagtcagcaa
    94321 gcgaccttcc agccactctt gtgctgtcaa agtatcgcca ttccccgttc gttttgtcca
    94381 aacaagtttt ggtgtaattc cttcccttga aagagcagcc aacatcggag tcgtgtttcg
    94441 tttaataaag actttgtcct catcacgcat gcctatgtat gtttttcctg tgtcgccttt
    94501 gatgggacgt aaccgccact cttggtctaa ctgaaactcc atcatgcatt ctcccgtcct
    94561 cttactcttt gttttgcagt acttattatt ctagtcgcct gaacactaca cgtcaagcac
    94621 atatacgttc tttttcattt aattgccatt caaaaaacca gcttttctca aaaaaaatag
    94681 aacgaacagc attcttactg tcaacgctct atttttcatt ctcattttta ccctacacag
    94741 ctttgttttc agtctgacat cttcttcaaa cgagttggta catatagttt aacaaagagc
    94801 atagtaacaa tcaaataagc cgctagcgga acccatcgct gctgcccatc taatacgact
    94861 gcagcaatca aaccaaaaat aaccgacgcg ataattaata cccatgtgag tagatactga
    94921 atcgcctgct tcttctgatt cttatggatt ggataaagct gaacgagaac catatagcgg
    94981 aactggttcg ctaaaggtaa cagttggaaa ccgatcaaat ataaaaataa gaaaccgata
    95041 atcagactaa aataaaagtc gactactccg gcaatcaata acccacctat aattactaat
    95101 cggaaataaa gaccactaaa atcagaacct cttgccaatc ttcttgcaaa caagtaaaga
    95161 taagtgtttt ttgattctct tttaatatga gtcaatatag gatccaaata gcgtcttctt
    95221 ttgatctttg ccgtaatttc aggaacatct gtgaataaat tgataaattg atagatctga
    95281 tgcaacctat gttcttctac atgcaccatt ttctcccaat ccaatccttt ttcttgttgc
    95341 ttccacaaaa accagtaata tagacttgcc tgtactaatg cacctgctat tcctgcccat
    95401 attagccaat aaaatgatag aaacaaaaag atcagagaag aaaaaaacca gcctaatttc
    95461 caataacgaa taacttgttg atctagtcga aacaattctg ctctcttgat ttgcagatga
    95521 ctgaatttca aactccataa tatgatcaga tagacgaaaa acatcgaaaa ggattgctcc
    95581 gtactaacca ccactaatgg catggccaat ccgcatgcca atatcaaaaa gatcaacgga
    95641 aaaatgcaag aatagcgaaa agctcgttcc aaataggttt gcatttcttt ttctttagga
    95701 agtaaaaaaa caatatctgc tgcctctgca aaagtagcca tcttacccac gaataaacag
    95761 agcatccaaa atacagagat tatgagccct ccaattgcaa acggtggctg cagggttttc
    95821 aaccaattag aataatataa tcccacaccg ccaatcaaga aaagacaaac taaaacaaaa
    95881 tgatcgttca atacataacg catatatttc atcattttct tttgatgtct tgctaaacgt
    95941 ttttgaaaaa aactactcat gtgcctgctc ctttgttaaa gcaatataga tttcgtccaa
    96001 agaagaatcc ggcagctgaa attcttttct caacatctca agagaaccgt ctgctcgtat
    96061 ctctccgtta tgtaagacca caaaacgatc acaatatttt tctgcagtag ctaaaatatg
    96121 cgtagacatc aaaataccgg ctccttcttt tttcatttct accatcaatt caagcaatgc
    96181 attgatagct agtggatcca agcctaaaaa tggttcgtcg atgatatata aagaaggctc
    96241 gatcaaaaag gcgcataaga tcatcacttt ctgtttcatt ccctttgaaa aattagctgg
    96301 gaaccagtca agacgattag ataaccgaaa agtctccaac aacttttctg ctcttttcat
    96361 tgctatatcc ataggtatat cgtaggccat cgcagtgact tcgatatgtt ctctcaatgt
    96421 caattcttca tataaagaag gagtctctgg aatataccca atttgtttgc gatattcttc
    96481 cgtatttttc tttaaggata gatgattgat ttctatcgtt ccttttgaag cttccagcag
    96541 accgataatg tgcttgatgg tcgtactttt ccctgctccg ttcagtccaa tcaaccctac
    96601 tatctctcca ggctgtacat cgaaactgat atcttttaac acagggagat gtccgtaccc
    96661 ccctgtgaca tgatcgataa ttaaactcat tctttttcct ccgccattta tttttattta
    96721 ttataccacg aagaaaatga cggtattttg tttttttcct tacaatagct ttaacttatg
    96781 gtaaagttaa gctgaagtat ttattcttta tagaaaggat gttttatatg gaaaactgta
    96841 ttttttgcaa aatcatcaat caagaaatcc caagctataa aatatatgaa gacgacaagg
    96901 tctatgcttt tttagacatc tctcaagcaa cgaaaggaca cacattagtt gtgcctaaac
    96961 gtcatgtagc agatattttt gaatatgatc ccgaacttgc aggagaggtt ttttcgcgtg
    97021 tgcctaagat tgctcaagca ttggaaaaag cttttccaga aatgaaaggt cttaatatct
    97081 tgaataacaa ccgtgaacta gcctatcaat ctgtttttca ttcacatatc catttagtcc
    97141 ctcgctacag caaagaggat gatttttcta ttcactttgt caatcatcaa gatagttatg
    97201 gatcggaaga actaaaagct attcaagaaa caatcgtaaa gcaggtgtcc tgcgatgatt
    97261 aaaaactttt tcaaaggact gttatttgga gctgctgctg gcactgtcgg aggtctgtta
    97321 ttggcgccca ggagcgggaa tgaaacaaga aagaaactga tcgaagaatt ggaagaagca
    97381 acaactctga caaatgattt aaataacagc ctgaatcatt ttaaaagcgc attgatcgaa
    97441 acaaaagaaa cagctgaatc tgtgattcct gctttccaag aagcaatcaa aaaagatatc
    97501 gaagatttta aattccaagc cgaaccacgt atcacacaaa tcaatgaaca agtagaaaaa
    97561 ctaaaagctg atctgccaga gtatcctgaa caaatataat aatgattatt ttctcaacag
    97621 atttaactat ataagtgaga aaagtttgcg tatttcctag gaatgtgatg aaattttgaa
    97681 ttttgtttga aactaccacg acaacgtttt taaaggaaat gggatatggt atagttaata
    97741 tataaaaata ataactaatt acaggagtgc aaattttaat gaaaaaaaaa tcaattattt
    97801 tggcagctac tagtgcgttg gctgttttaa ctctagcagc ttgttcaggc gatactaata
    97861 aagatatcgc aacgatgaaa ggcggaacga tcactgtatc tgatttctat gatgaagcaa
    97921 aacttgaatc atcgaaccaa tccttagtac aacggatgat catttataaa gtattcaata
    97981 acaaatatgg cgataaagta accgataagc aagtggatgc agaatacgac aaacaagcga
    98041 aatcattagg tgatactttt gaatcacaat tagaagctgc tggatatacg aaagatactt
    98101 ataaagaata tattcgtaac aatttagctt ttgaagctgg cttgaaagct cacgtagata
    98161 ttacagatga cgatttgaaa actgcttgga aatctttcca tccagaagta gaagcacaaa
    98221 tcatcaaatt atcaagtgaa gatgaagcaa aagatgtgaa aaaatcagcg gatgatggag
    98281 atgatttctc taaattagcc aaagacaaat caactgatac agagacaaaa gaagatggcg
    98341 gtaaagttaa attcgactca acgacaacaa ctattcctgc agaagtaaaa gaagcagctt
    98401 tcaaattgaa agacggtgag atctccgatg ttattactac aacaaatcct acttcttatg
    98461 cgacagaata ctacgttgtc aaaatggtga aaaaccaaaa taaaggcaat gacatggata
    98521 aatacaaaga tcaactaaaa gatatcgcta ctgaaactaa actaagtgac aatgcattca
    98581 caactaaagt aatcggtgaa gaattaaaag atgcaaatgt aaaaatcaaa gatgatgcct
    98641 ttgaaaatgt gttgagtgca ttcacaacaa cttcatcaag tacgaaagac tcaagtgaaa
    98701 ctacagcttc aacaaagagt tctgacacaa aatcaactga ttcaacaaaa gaatcttcaa
    98761 ctgaagaaac aactgattca tcaaaataaa agaaaacaaa aaaagcgaag acttatgtct
    98821 cgcttttttt gttttgaatg aaaaaaataa atttttgcta taaatctttt ggtacataga
    98881 aacttcggtt gtccataccg aaaatccgat cggtgtattt tcctggttct gtttgacgaa
    98941 tcgaagtcaa catcatctgc atcgaagcat cgatattgtc gatttgatgt aatatttctg
    99001 cttccattat tcttggacgt acaggtgagc catattctaa taagccatgg tgtgctaaaa
    99061 ccatatgacg taatacgaga acatcttcgt cagcttcgct gattttcaac gcaagacagg
    99121 ctttagttat ttcttcgtca atcaatacca gatgaccgat caaatttcct gcaagcgtat
    99181 attctgtcga cataggaccg gaaagttcaa tcacctttcc taaatcatgc aaaatgatac
    99241 cagcatacaa caatgctcga ttcagctcag gatattcatc ggcgattgat ttccctaagt
    99301 gaagcattgt caaagtatga taagctaatc cactggcaaa tgcatgatgg tttctttttg
    99361 ctgccggaaa ctcaaaaaat tgtttttgat atttattaag tagatagcga acaatacgat
    99421 tccaatgcgc attggtgatc tcaaacaaca attgattgat ttcttcttcc atttcttctt
    99481 tcttcaaagg ggctctttcc atgtataaac taggctctcc tggctcatct acccttgtta
    99541 agcgcatatg aagaatcttt acttgagggt ttccttgata aacctctctt ttaccgttta
    99601 gaaaaacgac tgtgccggct gtaaatttat tgatttcctc ctccgaagca tcccagtatt
    99661 taccatcgat agtacctgaa gtatcttgga aagtaaaagc aataaatttt tttccgtttt
    99721 tagcgattct tacatctgca cttttgatca ggacaaattg ttcaaactgc tcatcgatta
    99781 ctaaatcacg aatttttttc attatttgct ccttctaatt gttttacgat ttggttcatc
    99841 tcatggtaat agcttaccat ttctttatca gaagaaaaac aaattatttg atacttttct
    99901 ccaaatttag ctaaaagttc agctaattga tactttcgct gatgatcata atgaagccag
    99961 ccatcatcaa tgatgatcgg gcatatcgaa cggttagctt ctaatgagag gtaagcaaat
   100021 ctcatcgcca taatcagctg atctttcgta cctgtagata actcatagat gggaaattct
   100081 gtatatccgt ctgttaaagt cagtgtatca tttttcagta atatcttctg ataatttcct
   100141 tttgttaaaa tacctaaata atcacctgct gctcttaaca actggggtaa ttgtctttca
   100201 ctcatctctg ttgaaagatc acctaagaat gtcccggcga tttcaagtgc tccccattcc
   100261 tccagtaatt cctgtaattt tgctttttgc cggctagctt gttgataaag ttcgtccaat
   100321 gtgccgtctc tttgcaactc ttctacttga agttggagtc gttgccgatt ttcacttgct
   100381 tctttttctt cttgctggag ttgggattgc ttttctttca gttggcgcag tcttacagat
   100441 aatttctctt ttgtcagctc ttcaggaaat agtggagtaa gcatttccga taattcattg
   100501 tatcttttca tctgctgttc ggcttgtttg gctttttgta aaaagacagg tacttccgaa
   100561 ggataagata agcctgcttg agtcaattgt tcgctgtatt cttgtatcca tactttttgt
   100621 ttctttttca attgattgat ttcttgcttc aataaagtat tttgctgata gcttctggca
   100681 aatttcatct gttccatctc ttgtataaaa cgggaaagca ataccatttt ttctgaaatt
   100741 gtcttatctt gtatcggtaa ccattcttta acaaactcaa atttttggtc gatttgtcgt
   100801 agtttttctt gtatttcctg ttctctttta tgtttccgct caaatacgcc atataatttc
   100861 tgataatcta tgacttcctg tccatattct ttcatgagtt tgagcgtatc catctttcct
   100921 aagtgccgat gatccgcaaa acgatatact tcttgctgaa gaatctgttt ttcttctcca
   100981 gttctctttt gtttttcttc tgcttcagct aattgagcta aggctagatc aagttgtcct
   101041 agtttttctt gccacattcc ttttatctca gagaaatcat ttttagtttt aatttttggt
   101101 tgccttttgt agaagaaata gccaatcatg cctgcaccaa ttagtaaaag gatcactttc
   101161 aagggcattg gtacaaatat acctgcaatg attattgctc cgccagccat cagcatatac
   101221 ggtttagatg aagagactgg tgctatctct gactgatttt gtaataatgc tggataggtc
   101281 tcttccaagt cattcacttc tgcttcaatc atctcttgct gttctttagc tatttggaga
   101341 cgcacagaaa tctggctttc tagatcagca atccttcttt cttcagccag aagatgcttc
   101401 cattcttctt catataaaaa ttcttccggt aacggatttt tctgccaatg ccacctttgt
   101461 tccaaaatct tcaattctga atttgtttct ctagtctcaa tttgtaatct ttgccattct
   101521 tcgtttaatt gttccgctgt aaattgaagt tgctggagat cttttagttc ctgctcctgc
   101581 tctaaataaa aataatatct ggctgactgc tgatccatcc cgctatgctt ttccagtgtt
   101641 gcttctaatt cttccaaacg ctcatttgtt tgctgatacc gtttggagaa agactccaga
   101701 tctaaaagaa gttgctcatc aggaagacct gtagtgctgt tttttttgag agattgccat
   101761 tcttcatata aagaaaaatt aagttcttgc tgtctggcta atgaaaattg tttgttcgcc
   101821 tcttttaatt gtgccaataa ctgctgctgt tgcgactcgt attcctgttc ttgttggatc
   101881 aacttgccaa aataagcttc ctgttcttgt ttttgatgaa ttttttcttg cagctctttc
   101941 cattcattta atttttgatt gattagtaat ttttggcctt ttttcttgaa taattgttgt
   102001 gctttctgat aatattcttg ccgcttttgg aatacttgag aactgcccgt gatgcctaaa
   102061 gaaatcagcg catcatgtag ctctttttct ctcaaatgat ctagttccat caactgctct
   102121 tgctggaaag taaatacctg ctggaataac tctttcgtca aaggtgcgat cagtttttct
   102181 agtaactcat cacttcccac ttgatccccc agccacacct tcgattttcc gcgattttgc
   102241 tgcttgtagc gctcgacagc aaattcacca tatacaggat gtttaagcca tattttgccg
   102301 ccataggctg agccgtcttt tggtgtataa tccttttttt tacggccttt tgaagggaaa
   102361 ccaaataata ttgcttgaat aaattgataa atcgttgatt ttcctgcttc gtttccccca
   102421 tagatcagct gattgcctga ataaaagtca aaactttttt gacgccattt tccaaaagca
   102481 gcaatctcga tccttaaaat cttcattcct gatcctcctc aaataaaaaa tcttgattaa
   102541 gcagctgctt ggctttttca agtgtttctt cttgatattc cggcagttcg ctcaatattc
   102601 tagccgcttc ttgatgacta tatacttcat ttaaaatttg ttggaaatct tgaggtgtct
   102661 gatagtattg aaataactgt tccatcaatt tagcagaagc agcaagtggg gtcttcgtat
   102721 aaaaagtatt ctctatgaga gaaatacgcc aaataaagaa atcatttatc ctatctgaga
   102781 attcctctaa caaatagtct aatagctctc ctgattgtat ccgttccaaa acatctgtat
   102841 tgagatggtc ataatctttt aattttatct caattaaact aaatccatcc tctacttttg
   102901 aaagctgctg acgaatgtga acaatgacct cttttgtcgt tcttgctttc ctcaatgata
   102961 tttcctttgt cttccaatag acctctgcta ctttaatcgg atgtatttgg caacttcctt
   103021 tacttaattc aactagtaga atagatgtag aagcttgttc ctttttagta tgaccttgag
   103081 gcgcacctgg ataaacaatt gtttgctttt catttaagac cgttggcaca tggatatgcc
   103141 ctaaagccca ataatcgtat cccttttctt gcatctttga gggttggaaa ggagcatagt
   103201 ttcctttttg agagacgcca ggttccccgt ggtacaaccc aatatggtaa tctgtgagtt
   103261 ctctagaagg aaattccatc actttgtctt tttgaatcca cggttgacga taactaaatc
   103321 cactgagaga gacagtttct ccacttttta tcgttatttt ttttgtctct accgtttcgg
   103381 atgtaaataa atggacattt ttaggaaagg agaaccaata ccgctctttt tgatagaaat
   103441 catgatttcc gaatattata aatacaggta tatggttctt ttctaaccgt ttcatctgtt
   103501 ctgaaaaatg tttctgtatt tttaatgaag gacgattttg atgaaaatta tctcctgcaa
   103561 gtaaaacaaa atcaacgtta tttattattg cctgttcaat gatatttgat aaaacggtca
   103621 gattcgtctt caatagtttt tcctgtacag ttttatcaag agttgtcagt ccttcaaatg
   103681 accgatccat atgtaaatct gccgcatgga taaatttcac cattaaaaat ttcctccttt
   103741 ttttctttta tcataccatt ttcaatgttt tttttcatca ataaccgaaa atttgttcgt
   103801 attatgcaaa gaaattacga taaatggccg acttcaaaaa ataagtttat tcgaaaaaaa
   103861 gattgtgaca tgatttttgt cacaatccta aatatctatg ttatattcgc ttcgtttgac
   103921 actgaagaag tactatttgt actggaattt atgctccatt tttccgtatt tagaattcta
   103981 tgttctatac taccttaatt agtttatatg gtaagaattc tttcaaatgc ttgagatact
   104041 ccgtctttat catttgaaac agtgacataa tcagcttttt tcatgatttc ttgatgacta
   104101 tttcccattg caaaactaat atctgcactt tcaaacatag ataagtcatt taaactatct
   104161 ccgatcgcga ttctcaaagg tttctttaaa ttgtagattg attccaaacg atcaaacacc
   104221 acacctttag atacattttg aggtacgatt tcaatattta caggtgccga ttcagtaaca
   104281 gacacattta gcatcttttt caaatggtta aatatattag ctttcaattg acgattagga
   104341 ataaaaataa aaaatttgta aatgctgata gcatcctttt ctataatttc ctcaatatta
   104401 ttataaggga ttgaacaaat agatttttca tactcaagct catagtttag ctctttgata
   104461 gaaaattcac tccctacctc gtgaaaaatt tttttcattt tatttttata attctgagat
   104521 tcataacttc cgagatttgt atatattttg gttggaaatt tcgataggac agaatcaatt
   104581 ttttttacat catttttatc gaaggaagac tcaaatatct ttttttctcc atcaaatcca
   104641 acagaaccat ttaaccctac tgctggtatc cttaaaccag attttttgag aatattatta
   104701 atgtcttcta cttctcttcc agaacaaatg aatggaaaac agtcttccgg taaatgtttc
   104761 attgttcttg catttttttg actaatgctc tggtcagaat tcaaaagagt accgtctaaa
   104821 tctataccaa ttagtttcat ttcatccatg tctcctatac gttgattata aattcactgc
   104881 ttattgtaag tctaaatttc tcacaaaaca tatactaatt atacctaatt taagtaagta
   104941 caaacatcat tttaagaata ggaaaggaca tttat
//
LOCUS       DACGMI010000004        90639 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.004, whole genome shotgun sequence.
ACCESSION   DACGMI010000004 DACGMI010000000
VERSION     DACGMI010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 90639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.004"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..539)
                     /locus_tag="IXT46_000333"
     CDS             complement(<1..539)
                     /locus_tag="IXT46_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4946280.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYK"
     gene            complement(536..2431)
                     /locus_tag="IXT46_000334"
     CDS             complement(536..2431)
                     /locus_tag="IXT46_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4946281.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(2489..4264)
                     /locus_tag="IXT46_000335"
     CDS             complement(2489..4264)
                     /locus_tag="IXT46_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4946282.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(4314..5810)
                     /locus_tag="IXT46_000336"
     CDS             complement(4314..5810)
                     /locus_tag="IXT46_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4946283.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(6004..7626)
                     /locus_tag="IXT46_000337"
     CDS             complement(6004..7626)
                     /locus_tag="IXT46_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAQ4946284.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(8075..9388)
                     /locus_tag="IXT46_000338"
     CDS             complement(8075..9388)
                     /locus_tag="IXT46_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAQ4946285.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(9633..9857)
                     /locus_tag="IXT46_000339"
     CDS             complement(9633..9857)
                     /locus_tag="IXT46_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946286.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(9877..10245)
                     /locus_tag="IXT46_000340"
     CDS             complement(9877..10245)
                     /locus_tag="IXT46_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4946287.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(10442..11152)
                     /locus_tag="IXT46_000341"
     CDS             complement(10442..11152)
                     /locus_tag="IXT46_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946288.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(11170..11667)
                     /locus_tag="IXT46_000342"
     CDS             complement(11170..11667)
                     /locus_tag="IXT46_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4946289.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(11704..12156)
                     /locus_tag="IXT46_000343"
     CDS             complement(11704..12156)
                     /locus_tag="IXT46_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4946290.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(12291..12896)
                     /locus_tag="IXT46_000344"
     CDS             complement(12291..12896)
                     /locus_tag="IXT46_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAQ4946291.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(13346..13966)
                     /locus_tag="IXT46_000345"
     CDS             complement(13346..13966)
                     /locus_tag="IXT46_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4946292.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLCQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(13968..14837)
                     /locus_tag="IXT46_000346"
     CDS             complement(13968..14837)
                     /locus_tag="IXT46_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAQ4946293.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(14860..15267)
                     /locus_tag="IXT46_000347"
     CDS             complement(14860..15267)
                     /locus_tag="IXT46_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAQ4946294.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(15286..16575)
                     /locus_tag="IXT46_000348"
     CDS             complement(15286..16575)
                     /locus_tag="IXT46_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4946295.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(16602..16904)
                     /locus_tag="IXT46_000349"
     CDS             complement(16602..16904)
                     /locus_tag="IXT46_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4946296.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(16929..19022)
                     /locus_tag="IXT46_000350"
     CDS             complement(16929..19022)
                     /locus_tag="IXT46_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4946297.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKVFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(19511..20275)
                     /locus_tag="IXT46_000351"
     CDS             complement(19511..20275)
                     /locus_tag="IXT46_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAQ4946298.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(20386..21255)
                     /gene="mdcB"
                     /locus_tag="IXT46_000352"
     CDS             complement(20386..21255)
                     /gene="mdcB"
                     /locus_tag="IXT46_000352"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAQ4946299.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(21280..22356)
                     /locus_tag="IXT46_000353"
     CDS             complement(21280..22356)
                     /locus_tag="IXT46_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAQ4946300.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(22380..22973)
                     /locus_tag="IXT46_000354"
     CDS             complement(22380..22973)
                     /locus_tag="IXT46_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAQ4946301.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(22977..24653)
                     /gene="mdcD"
                     /locus_tag="IXT46_000355"
     CDS             complement(22977..24653)
                     /gene="mdcD"
                     /locus_tag="IXT46_000355"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAQ4946302.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(24643..24942)
                     /locus_tag="IXT46_000356"
     CDS             complement(24643..24942)
                     /locus_tag="IXT46_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAQ4946303.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(25044..26690)
                     /gene="mdcA"
                     /locus_tag="IXT46_000357"
     CDS             complement(25044..26690)
                     /gene="mdcA"
                     /locus_tag="IXT46_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HAQ4946304.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(26697..27608)
                     /locus_tag="IXT46_000358"
     CDS             complement(26697..27608)
                     /locus_tag="IXT46_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAQ4946305.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            27728..28585
                     /locus_tag="IXT46_000359"
     CDS             27728..28585
                     /locus_tag="IXT46_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4946306.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(28772..29134)
                     /locus_tag="IXT46_000360"
     CDS             complement(28772..29134)
                     /locus_tag="IXT46_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946307.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            29480..30919
                     /locus_tag="IXT46_000361"
     CDS             29480..30919
                     /locus_tag="IXT46_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4946308.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(30926..33478)
                     /locus_tag="IXT46_000362"
     CDS             complement(30926..33478)
                     /locus_tag="IXT46_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAQ4946309.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMAFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(33592..34923)
                     /locus_tag="IXT46_000363"
     CDS             complement(33592..34923)
                     /locus_tag="IXT46_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4946310.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(34889..36367)
                     /locus_tag="IXT46_000364"
     CDS             complement(34889..36367)
                     /locus_tag="IXT46_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4946311.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(36672..38507)
                     /gene="tdc"
                     /locus_tag="IXT46_000365"
     CDS             complement(36672..38507)
                     /gene="tdc"
                     /locus_tag="IXT46_000365"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAQ4946312.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            38977..40404
                     /locus_tag="IXT46_000366"
     CDS             38977..40404
                     /locus_tag="IXT46_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAQ4946313.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(40496..40861)
                     /locus_tag="IXT46_000367"
     CDS             complement(40496..40861)
                     /locus_tag="IXT46_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAQ4946314.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPLDVQNK"
     gene            complement(40858..41223)
                     /locus_tag="IXT46_000368"
     CDS             complement(40858..41223)
                     /locus_tag="IXT46_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAQ4946315.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(41415..41663)
                     /locus_tag="IXT46_000369"
     CDS             complement(41415..41663)
                     /locus_tag="IXT46_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946316.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            41662..41790
                     /locus_tag="IXT46_000370"
     CDS             41662..41790
                     /locus_tag="IXT46_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAQ4946317.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            41847..43541
                     /locus_tag="IXT46_000371"
     CDS             41847..43541
                     /locus_tag="IXT46_000371"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAQ4946318.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            43608..43814
                     /locus_tag="IXT46_000372"
     CDS             43608..43814
                     /locus_tag="IXT46_000372"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946319.1"
                     /translation="MFLIWLDLLPQMQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFL
                     TWLDLLPQMQAFEHRLPRGYEKGV"
     gene            44192..45325
                     /locus_tag="IXT46_000373"
     CDS             44192..45325
                     /locus_tag="IXT46_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAQ4946320.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            45356..45676
                     /locus_tag="IXT46_000374"
     CDS             45356..45676
                     /locus_tag="IXT46_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946321.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(45705..46169)
                     /locus_tag="IXT46_000375"
     CDS             complement(45705..46169)
                     /locus_tag="IXT46_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4946322.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(46301..47554)
                     /locus_tag="IXT46_000376"
     CDS             complement(46301..47554)
                     /locus_tag="IXT46_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4946323.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(47583..47900)
                     /locus_tag="IXT46_000377"
     CDS             complement(47583..47900)
                     /locus_tag="IXT46_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4946324.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(47926..48246)
                     /locus_tag="IXT46_000378"
     CDS             complement(47926..48246)
                     /locus_tag="IXT46_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4946325.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(48710..50125)
                     /locus_tag="IXT46_000379"
     CDS             complement(48710..50125)
                     /locus_tag="IXT46_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4946326.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(50142..51458)
                     /locus_tag="IXT46_000380"
     CDS             complement(50142..51458)
                     /locus_tag="IXT46_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4946327.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(51608..52306)
                     /locus_tag="IXT46_000381"
     CDS             complement(51608..52306)
                     /locus_tag="IXT46_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAQ4946328.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(52595..53584)
                     /locus_tag="IXT46_000382"
     CDS             complement(52595..53584)
                     /locus_tag="IXT46_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAQ4946329.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(53664..54497)
                     /gene="msrA"
                     /locus_tag="IXT46_000383"
     CDS             complement(53664..54497)
                     /gene="msrA"
                     /locus_tag="IXT46_000383"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4946330.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(54672..56306)
                     /locus_tag="IXT46_000384"
     CDS             complement(54672..56306)
                     /locus_tag="IXT46_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946331.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLIVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(56293..58140)
                     /locus_tag="IXT46_000385"
     CDS             complement(56293..58140)
                     /locus_tag="IXT46_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946332.1"
                     /translation="MFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKDNSSILKI
                     ELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLSRIKGLSS
                     IFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLLNICTILI
                     SFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAYGLI
                     FNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVVNLV
                     KAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITTYTM
                     GLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQFPWR
                     ILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQSKHG
                     HIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAADNNI
                     TYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEITTKY
                     TPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            58127..59764
                     /locus_tag="IXT46_000386"
     CDS             58127..59764
                     /locus_tag="IXT46_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAQ4946333.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(59909..60649)
                     /gene="truA"
                     /locus_tag="IXT46_000387"
     CDS             complement(59909..60649)
                     /gene="truA"
                     /locus_tag="IXT46_000387"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAQ4946334.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(60840..61475)
                     /locus_tag="IXT46_000388"
     CDS             complement(60840..61475)
                     /locus_tag="IXT46_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAQ4946335.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(61622..62863)
                     /gene="sstT"
                     /locus_tag="IXT46_000389"
     CDS             complement(61622..62863)
                     /gene="sstT"
                     /locus_tag="IXT46_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAQ4946336.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            63061..64059
                     /locus_tag="IXT46_000390"
     CDS             63061..64059
                     /locus_tag="IXT46_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946337.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            64072..66090
                     /locus_tag="IXT46_000391"
     CDS             64072..66090
                     /locus_tag="IXT46_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HAQ4946338.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(66150..66866)
                     /locus_tag="IXT46_000392"
     CDS             complement(66150..66866)
                     /locus_tag="IXT46_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAQ4946339.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(67093..67635)
                     /locus_tag="IXT46_000393"
     CDS             complement(67093..67635)
                     /locus_tag="IXT46_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAQ4946340.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(67640..67867)
                     /locus_tag="IXT46_000394"
     CDS             complement(67640..67867)
                     /locus_tag="IXT46_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper resistance protein CopZ"
                     /protein_id="HAQ4946341.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(67946..69826)
                     /locus_tag="IXT46_000395"
     CDS             complement(67946..69826)
                     /locus_tag="IXT46_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAQ4946342.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(70015..70629)
                     /locus_tag="IXT46_000396"
     CDS             complement(70015..70629)
                     /locus_tag="IXT46_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4946343.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            70771..71331
                     /locus_tag="IXT46_000397"
     CDS             70771..71331
                     /locus_tag="IXT46_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4946344.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(71636..71950)
                     /locus_tag="IXT46_000398"
                     /pseudo
     CDS             complement(71636..71950)
                     /locus_tag="IXT46_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(72204..73839)
                     /locus_tag="IXT46_000399"
                     /pseudo
     CDS             complement(72204..73839)
                     /locus_tag="IXT46_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(74394..74957)
                     /locus_tag="IXT46_000400"
     CDS             complement(74394..74957)
                     /locus_tag="IXT46_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAQ4946345.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLVDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
     gene            complement(74972..76015)
                     /locus_tag="IXT46_000401"
     CDS             complement(74972..76015)
                     /locus_tag="IXT46_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946346.1"
                     /translation="MTQRVAIMILVLLVIGLLVYYVLKFKHWKQQRIHQDIEKKLKRY
                     PIVQAAWEKAEAKQYNIPGLTETRMVVPETGENEVCQWMTPQGLAFSQDFVFISAYCY
                     DHQHHSIIHVLDRETGQPIKLLILPKRPHVGGLVYDTKRELLWLTITGSATGRVAALR
                     LIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQLVSGNFTLKGEGQLTFYLL
                     PTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHYLLASRSYGPYTSELLVSER
                     DSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYREKANPVLANVLLLDLATLLH
                     ANKRPKKIAATKK"
     gene            complement(76148..76552)
                     /locus_tag="IXT46_000402"
     CDS             complement(76148..76552)
                     /locus_tag="IXT46_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAQ4946347.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYQIGVVLEVSLPGLEK
                     DQAEKIAEEAHAFCPYSKATRGNIDVEVTIVE"
     gene            complement(76785..77420)
                     /locus_tag="IXT46_000403"
     CDS             complement(76785..77420)
                     /locus_tag="IXT46_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAQ4946348.1"
                     /translation="MIFLQKYGFYFLLLGVMSDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILVVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(77686..78738)
                     /locus_tag="IXT46_000404"
     CDS             complement(77686..78738)
                     /locus_tag="IXT46_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4946349.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(78751..79689)
                     /locus_tag="IXT46_000405"
     CDS             complement(78751..79689)
                     /locus_tag="IXT46_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAQ4946350.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(80140..80790)
                     /locus_tag="IXT46_000406"
     CDS             complement(80140..80790)
                     /locus_tag="IXT46_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946351.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNINHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(80890..81399)
                     /locus_tag="IXT46_000407"
     CDS             complement(80890..81399)
                     /locus_tag="IXT46_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HAQ4946352.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(81600..82469)
                     /locus_tag="IXT46_000408"
     CDS             complement(81600..82469)
                     /locus_tag="IXT46_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4946353.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(82489..83610)
                     /locus_tag="IXT46_000409"
     CDS             complement(82489..83610)
                     /locus_tag="IXT46_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAQ4946354.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(83612..84007)
                     /locus_tag="IXT46_000410"
     CDS             complement(83612..84007)
                     /locus_tag="IXT46_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4946355.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(84026..84823)
                     /locus_tag="IXT46_000411"
     CDS             complement(84026..84823)
                     /locus_tag="IXT46_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010238514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4946356.1"
                     /translation="MSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALSPIL
                     RKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKVGTM
                     GPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEFGYK
                     QGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQPMLD
                     KILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(84825..85613)
                     /locus_tag="IXT46_000412"
     CDS             complement(84825..85613)
                     /locus_tag="IXT46_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4946357.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(85627..86103)
                     /locus_tag="IXT46_000413"
     CDS             complement(85627..86103)
                     /locus_tag="IXT46_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4946358.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(86175..88832)
                     /locus_tag="IXT46_000414"
     CDS             complement(86175..88832)
                     /locus_tag="IXT46_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4946359.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKK
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(88851..89255)
                     /locus_tag="IXT46_000415"
     CDS             complement(88851..89255)
                     /locus_tag="IXT46_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HAQ4946360.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(89487..89744)
                     /locus_tag="IXT46_000416"
     CDS             complement(89487..89744)
                     /locus_tag="IXT46_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HAQ4946361.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            complement(89869..90201)
                     /locus_tag="IXT46_000417"
     CDS             complement(89869..90201)
                     /locus_tag="IXT46_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946362.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
BASE COUNT        27730 a        18447 c        14613 g        29849 t
ORIGIN      
        1 tttttatagc gtttgaatac tgtttcagcg aaacgaacgt aaaactgaat aagctttcga
       61 ttaggccatc caccatattc tgtaaccaaa tataacggca tttcataatg ggaaagagaa
      121 acgactggct caatcccata ttttagacat tcgtcaaaca cttgatcata aaaaaataat
      181 cccgcttcat tgggtgtttc ttcatcacca tgaggaaaaa ttcttgtcca tgcgatagac
      241 atccgatagc atttaaaacc catttcagca aataaacgga tgtcttcttt aaagtgatga
      301 tagaaatcat ttccgtgtct tttaggataa taatacttgc tgttgggatc ctgcgccgct
      361 tttacttgct gatgcgtcat catatgccat tgatctgtcc atttttcttt aggtaaatcg
      421 ctgtcgaatg tatacacatc agacacagat aatccttttt catctacatc ccatgcacct
      481 tcacattgat tggccgctgt cgctccgccc cataaaaatc cttctggaaa ttttttcata
      541 tcgatccccc taaacttgct agttttcttg tttgattatt tttcttatga ctagtaatga
      601 tatttttgaa tctactacta tttgtaacaa taaccattgt ggtcggatca tatccctctt
      661 tgattaattc ttgcaaatct acttccatca ataaatcgcc tttacgtact ttttttccat
      721 cagatactgc actttgaaag tatttgccat ttaaattcac tgtatcaata ccgatatgga
      781 tcagtatctc tgctccttct tcactgacta ccccaattgc atgtttcgtt ggaaaaactg
      841 ttgaaacttc cccgtttaca ggactgtaga tttttccgtc cgttggaatg atcgcaaacc
      901 cttctcctaa agatccacta gcaaatgttg gatcgtttac ttcagataaa tcaattattt
      961 cacctgctgc aggagtactt aacactatat cctttgagga ttcttcttcg atttcatcct
     1021 tgtagccgaa aagaaaagtt agcatacagg aactgatcat cgctaagaaa taactagcaa
     1081 ctagccaaac aaatccttca ccaatataaa tcgggaaaga caaaatactt cttgtagcaa
     1141 ctgccaaagc accggctcct gcggcaccag ctactccacc aaatatagct ccacatatac
     1201 aagcaatgta aaatggtcgt ttatatttaa gagtcacacc ataaacagca ggttcagtga
     1261 ttccaaataa tgctgtgata aatgcagata aagataaact ttttactttc ttatttttcg
     1321 ttttcaaaaa taccccaagt actgctcctg cttgcgcagc tacggcagtc atacatgctg
     1381 gacctagcgt atcacgaccg tagaaagaaa gattgttggt cattactggt acaagtcccc
     1441 aatgtaaccc aaaaatcact aacacttgcc aaaatccgcc gataacagca ccagataaaa
     1501 cagggctaaa gttataaaca gctaaatatc cagctgcaat cagctgactt gcataatctg
     1561 caattggacc tacaactaat aaagtaattg ggaccatcac gatgatacaa atgaatggtg
     1621 tcaataaatt tcgaatactt tcgtgcaagc ttttgcgaat cttaggctca atataagaaa
     1681 gaacccatac agctaaaatt gctggaataa ccgtacttgt ataccttgct agaatcacgg
     1741 gcatccctag aaatcgcaag gttatgctat cactatatgc actgacaatc gtaggataaa
     1801 cgagagctgc tgcaataacc atagcgatga aacgatctgt attgaacttt tttgcagcag
     1861 tatatgccaa aaatataggc aagaaataga aaaatgcatc agctgctgca ttcaaaatga
     1921 tataagttcc tgattcagta gttaataaat tcaaactcgt acataaggcg agtactcctt
     1981 tgatcaaacc acttcctgcc aagacgccta aagtcggggc aaaaacagcg gcgatcatgt
     2041 ctataaaaga gtttaaaatg ccttttttct cagttcctct ctttccacta gatgcatcat
     2101 cttctagttt catttgtttg gataatacgt catacacttc atttactgca tttcctacta
     2161 cgacttgaaa cattcctcca gcttcgacta cagtgatcac accttctagt tgctctacct
     2221 tctccttatc tgccttctta ttatctttta gggtaaagcg taaccttgtt gcacaatggt
     2281 aaacattgct gacattttct tcgcctccga caaatcggac aatatctttc gctaattgtg
     2341 aatagtccat ttttacttcc cccttgttaa ttaatgccgt agcaatcctt cttacaagat
     2401 aagtatagtt cttagaaaac ggtttctcca ttcaattagt accccttata atagcgaacg
     2461 aaactgtaca atagtgtgta tggtttactt agccgagcaa atcactcact gcttgaaaga
     2521 aaacaagtat atcgtttctc ttatagtcaa aggagacaaa aaaaacacgc ttgatcttcc
     2581 tttgctgatg tataagtggt atctcaagct gatactctgt gatttttgtt tctacttggc
     2641 ttttgataag acagcacaac aaagtctcgg catttaacgg aagcataact aggtcagaac
     2701 taggagagat tagttgctga atggaatcta tctttttatg gatttttatt tgattttctt
     2761 ctttgtagta atgatcaagc agttttgttt tctttttttc ttcaactatg gtcagctttt
     2821 cacgcaaaat ctgataaatc tcccaagatt caaactcatc tagaacacta ggtagataaa
     2881 tcaaatcatc ccactcaaaa ataagctctt gctcagtagt caaaattgca tcatattccg
     2941 ttattttgtt tgattgattt ttgaaaagat acactggttc tatccggcat tctttgatcc
     3001 acatgttcat actttgttga atctgttttt ttagtgtatt caaaatacta attggctggt
     3061 tactaacaat cagtatctcc ccttgttttc gaaaaggatt caacgcttcg gcaagataca
     3121 aaacaaaata agcgctttca gctaaattgg gacgtaattg aaaatgtatt gggaagaaac
     3181 gccgaattaa ataaatttct aaaggataac gggagatgat cttttgtaca aaatgattca
     3241 tggtattatg tccggcatcc atcctcgttt tcatttgttt gatatgggtt agcaaaaatt
     3301 ctgtttcatg gaacaataac gaaacaggaa gatctaaaaa acgaataatc gtttgctcaa
     3361 atgctcttag attcttctct atttctttgt ttttttcatc attaatcatc aaataattta
     3421 actctaatag tcgattttca attgcttgtt tttcttgatt ggaaaaagaa tagggtagtt
     3481 ctgatgataa cttttttgtg agggtctcta ccatcggaat aaataatgta tacctgtttg
     3541 ttttttctaa aagttcttct cttcgaagaa tggtcaaaac gagataccga gaaaatcgta
     3601 tgaagtcctc tcctgaaaca atataattat atgatataag aacctctttt aatgtctttt
     3661 ggacagtcgg catgatattg gaaaaaattg tactgatttg ttgaggcaac cttgcgtgtt
     3721 ggatcaccgt ttctgttcca acaagagata agaaaattct ttttgaattt tcttcagcaa
     3781 tgatttttag tccttttgtc gacgaaactt ccagttctaa tttaggattg cgctcgatcc
     3841 aacgcaaaat cgtttttatt tgtaatgata cggctgtttt tgaaagaaag aaaatgtctg
     3901 ctatcttttg catactgaca tacccttttt gaaacaataa gtacgtcaca atagttgaag
     3961 ctcggaaatc catgctggaa tagattttat gtttcgtcac ctcttgtatg atttgctgtt
     4021 tagtttcaga ttcaattgat tctaaaaaat aacctgaacg tttatttgac tggataatga
     4081 ttttcttctc gtagatagca agcatatttt tgatttcagt ttggatcgtt ttcttgttgg
     4141 tacctaaagc ttcagctaat tcttcgcttg ttatccaatg attcttattt cttaatacta
     4201 caagaatttg gagttgtcgt ttatttaagt ccatttgctt acacctcctc tttgttataa
     4261 acatacagga aaaacctctc aaatgacaat agtcacttgc agaggtttaa aaatcatttg
     4321 aagaaagatc tatattcaag gtttttacca ttagactgga taatttgttt ataatattca
     4381 aaactatctt ttttcaatct cctaaagctt ccgctcccat cattttgtct atccacataa
     4441 ataaagccat atcgcttcct catttcccct gttcctgccg atacgatatc gattggtccc
     4501 caccataagt aaccaatgat ttggcaacca tcttttattg cctcagcaat ttcctgaaga
     4561 tgtattttta gatactcaca acgttttgga tcgtggattc gattcaattc atctggtgct
     4621 tcatctagtc caatgccatt ttcaactatg aataatggta attcataacg gtctgtcaat
     4681 tcattcatga cataacgaaa ccctagagga tcaattggcc aactccaagg ttcgggagat
     4741 ttttccttca aaaagggatt atcgaaacca tttgctccgc cagtatctac gcgcatttct
     4801 gcttcttttt tatagacagc gctacgataa taactaaatg caatataatc tgccgtgtta
     4861 gcttgcaagc actgttcgtc tccatctaac attactggtg cacagtcttc ttccttccat
     4921 gtcctgtaaa tataagctgg ataatgccct cggcacatga catcggagaa aaaccatgaa
     4981 ttgcgtttaa attgcagtga accaaataca ttctctggat cacagtcata tgcataagtc
     5041 gctaatgcag aaaagctaca cataataccc atcttagcat ttggatcgat tttctttaat
     5101 aattgagtag cacgggcgtt cgctagaaac atatgatgac aggcttgata aatcactttt
     5161 tttgttagtg tagcaatggg ttcaagttta tctctagcag ggaatgtaac caatccagca
     5221 gctgcataag gcatacgaaa agcattattg atctcattaa aggtcatcca atatttcact
     5281 ttcccttggt agcgttcaaa gacggtctgc gcataaaatt caaaaaagtc gattaatttt
     5341 cgattttgcc accccccata ctctcctacc aatgctaagg gggtttcata atgactaaga
     5401 gtaattactg gctcgatatc atatcgattt aatgtattga ttagtctgtc ataaaatacg
     5461 agaccagcct catttggctt ctgttcgtct cctcttggaa atattcgtgc ccatgagatg
     5521 cttgttcgaa aagcttttaa acctaactcc ttcagtaaac gaatatcctc ttcaaatcga
     5581 tgataaaaat caatcgcttc atgagaaaga taatggagtg attcgtctaa agcaatctcc
     5641 caaatctttt tttcttcatt ccactgaata ctaggatgct ggttcatgat cccgataagc
     5701 gtatctgtca cattaggtaa tttgccgtct tccaaccatg caccttcaca ttgattagca
     5761 gctactgctc cgccccataa aaaattttct ggaaatattt cctgatccat aactatctct
     5821 cctcgctatc aacaatttct tacttgaagt atagctcgat tcatcaaaac aagatattct
     5881 aactatttcg gcagaagaga agaaaaaaat tgaatgctac tcttcatttt taatatttat
     5941 atataacaaa tacataagac gatccccgaa agaaaacact cgttaaccat ctaagcaaac
     6001 gatttatttt acttccaaca caaatgcttc ataaggtcgt aaatcaactt tgccgtctgg
     6061 taactgtttc agaggataat ttgacacaat aacccttaaa gcttcacgtg gaacagtgaa
     6121 cgtctgcttt tcactggaca tattacaaat aacgagccat tgctggtctt catatatgcg
     6181 agaataggca aagacatgct caggcgtctt ttccactaat tcatagtctc cccagacgat
     6241 gatgtcatgt tttctacgca aatcgatcaa tttcttgtac atataaaaaa cagaatcttg
     6301 atctgctaac gcttcttctg cattgatttc tttataattt ggattgactc gaagccatgg
     6361 aattccagta gtaaacccag catgttcacg ggcgttccat tgcataggcg tcctagcatt
     6421 gtctcttcct ttcgcattga ttgattccaa gatttcctct tttgtaaatc cagaagaaat
     6481 cctttcgtta tacatattga ttgtctcaat atcttttgct tccgcgatat catcgattgg
     6541 gcaattcgtc atgcctaact cttctccttg atagatataa ggggtgcctt tcatcatatg
     6601 gagcaagata gcaaacatct tggcactttc ttttcgatac acatcgtcat ttccccaacg
     6661 agaaacaatt cgcggaagat cgtgattatt ccaaaataaa ctattccatc cttcatcacc
     6721 taaagatgtt tgccatttgg ataatacttt tttcagttca gagatactca agggtttcaa
     6781 atcccatttg tctttgcctt cttgctgatc taatcctatg tgttcgaatt ggaagaccat
     6841 ggataattca tttcttttag gattggaata aagtttagcg atttcggtag ttgctcccca
     6901 tgtttcgcca acagtcatca gatttttgtc accaaaagtt gcttgattca tttcctgaag
     6961 atactcatgc agtttaggtc cattacttgt gatttcttta tccggttctt tgccaatcat
     7021 atcgatcacg tccatacgaa agcccccaat acctttatcg atccagaaat tcatcatttg
     7081 ataaatctct tggcgaacct gtttattttt ccaattcaaa tcaggttgac gcttgctata
     7141 caagtgcaga aaatattgcc ccgttttttc atccaactgc caagcagaac cactgaatat
     7201 tgagcgcaat ctattaggct cttttccatt gaccggatca cgccaaatat aatagtcccg
     7261 ataaggattt tctttatttt tacgggcctc aatgaaccac ggatgttcat cagaagtatg
     7321 attcaccacc agatccatga tgatacggat atttcttttc tttgcttctt caatcagttc
     7381 ttccatttct tccatcgtac cgaattctgc catgattgct tgataattac tgatatcata
     7441 cccattgtca tcattcggag actcgtatac tggagaaagc caaattgcat caatacctaa
     7501 atacgccaga taatccaacc tggaaataat cccccgcaaa tctccaatac catcttgatt
     7561 tgaatcttga aaacttcttg gatagatttg ataaacaact gaatggtgcc accatttttg
     7621 ttccatgatt ttcctcctat aaatggatgt ttctattttt tgcttaatca tttattttag
     7681 tctctctcac taaaaattgt aacgctttca aatagctatt gcaccttgtt atcggtaaca
     7741 gaataaaaca aaaaaacagc tgaggaaatt ccctcaactg ttttttgaaa ggattgattt
     7801 atgcagggaa gaatgctgat ttcacaactt ctttataaac ggtgttcact cagctgtccc
     7861 ttggtattag ctcaaaaaac ggcaaaatat gaggaactat tttttcgttt ttttctctaa
     7921 tactcaggcc agaacactga tttcacaacc tctttataaa cggtgttcac tcagctgtcc
     7981 ctcggtatta gctcaaaaaa cggcaaaata taagaaacta ttttttcgtt tttttctcta
     8041 atactcaggc cagaacgctg atttcacaac ctctttattt cacattcaat atccacatga
     8101 atcccacaaa tacaaagaac agaccataca tgattggaga tacttctttt cctcttttag
     8161 ctgctaacat ggtaattgga tagaagataa aacctaatgc aatcccatct gaaatactat
     8221 aagtcaaagg catgccgatc aagatcaaga atgaagggat cgcaatctct aagtttcccc
     8281 attcgatttg tcgcaaagat tgtgccatca atactcctac cataatcaat gctggtgcag
     8341 ttacttgtga agtaacaact gatagtaatg gagaaaagaa caagcctaac aagaagaaaa
     8401 tccctgtagt aatagctgtg atacctgaac gtcctccaac ggcgatacca gctgatgatt
     8461 ctacaaatgc accaacagga gaagtaccaa ataaggaacc cgcaagcata gctgttgaat
     8521 cagaagctaa agctttccct acacgaggca tcttgttgtc tttcatgaaa cctgcttggt
     8581 ttgctaatcc aactaaagtt cctgctgtat caaagaaagt cacaagcaag aatgtcagca
     8641 ctacgaccca catttgaaga gaattgatgt cccctacatg ttttaatgca actaaaaatg
     8701 ttggtttcaa acttggtgct gcggcaacaa tttcagaagg cattggaatc aaacctgtga
     8761 ccagacctaa aatcgttgta gctgccatcc cgatgaagat gccacctggt acacgccgaa
     8821 caagcaagat agcagttacg actaatccaa aaatcgtcaa ccaagtagaa ccaacgttga
     8881 gtgatcctaa tcctactaat gtagattcat tcgaaacgat gatcccacct tcgctcagac
     8941 caaggaaagc gataaataga ccgataccgc cagaaatcgc atatttcaaa tctgctggga
     9001 tcgcatcaat gatcatttcc cgcagcttga agattgtgat caaaataaaa atcaaagaag
     9061 caacgaatac gccggctaat gctgtttccc atggaatccc cattcctaaa caaacagaat
     9121 aagcaaaaaa agcattgatc ccaagagcag gtgccgttcc aattggataa cgggctaata
     9181 cccccattaa aacacagccg atcgcactgg ctaatgcagt cgcagtaaac actgctcctt
     9241 catccattcc agaagcacct aatacagttg gatttacaaa taagatataa gccattgaga
     9301 taaatgttgt aaatcctgcc agtacctcac gttttaccgt ggtgttcaat ttttctattt
     9361 cgaagtagga aagtattttt tccttcatct tccatccccc taaatccgaa cattataaat
     9421 aaagtccgtt aaaatttcga tttattaata aaacaacgtg ttttatcata tactaaaaca
     9481 aaacataagt aaacaaaaaa ttcggatttt aagcaaaatc cgaacgttcc atctgattaa
     9541 atccctttat ctcaaagttc atgaacattc actttggatt acaagaattt ctttattgtg
     9601 ttaataaagt ttcttcattc tagtctcaaa aatcaatagt gtgatttgat tttaccattt
     9661 cgtttctgtt cttctttgat gaattctttt gtatcgacag gattcagatt atttagtccg
     9721 ccaaaacctg tatcgaccat ttttccccag ccttttgtct tcttttttcc tgatttgaga
     9781 ttctttgctc gaagcttctc actatgtttt gctcgccgat acttcaaata accttctaat
     9841 cttcccatta gatccactgt ttttcctcct ttttattcaa tcagacgact cagcttttcc
     9901 tataacaaaa taattgcctt cagggtcaga aaaattgaaa gtcaagatgc cattgttatc
     9961 tgtgatttct cctggttctt ccatgttctc gtagatagtt tcaaattcat ccgtaaaaaa
    10021 tactaaagaa ggcggtggtc ctaatacctc tggtgaaaac ttctgcacaa atacttttgg
    10081 gaatacgcct aattctaatt cttttgagat gctgagtaca atactcttaa attcttctgg
    10141 caattcgatt gtttcagaaa tttctgcacc aattttttct acaaagaatc ggcaaatcat
    10201 ctctacgtca ttgacataaa gcatcacacg tgttttttgt atcatcattt gacccttctt
    10261 tctatttgat tttctttcct gtctataaac tgattccatt atatcacgaa agcgcaaaca
    10321 ccttgtgttt gatactattc aagaaaaata aagcaatagt ttctaggatt gctttcctcc
    10381 acaaactttt tttacaaaaa aaaaaacggc aatgaatgcc gctcttctta tttcgattct
    10441 tttataattc tgcttctgat tcatctttgg ttagtgtgtg tctaacacta gttacgccaa
    10501 atgtttgatc gattttttcc ttcaacgctt cgattgcctg tgcgccacgt gccgcttgtt
    10561 cagcattgat ggattcaatg accagcaccg ctgcttgtgt ttcttccgtc agcattgttc
    10621 tttgggcttc acgccagttg agacagcgac agatcgctcc ttgttcatca tagtagatga
    10681 tttcttccgg aagtgccgga gcatcggaat ctgcacctaa aggcaggaat gattcgccac
    10741 cttgggcttt tcctaaatgc agatttcctg cgatcttttc gatatcttct ccgccgcaag
    10801 gtacgccaaa agacaaggaa atactattat agatatctac aagcggattg attgggaaaa
    10861 attcccgttc ttgatttgca cgtttcagta aagcttcaat agaagaacgt gcaccttttt
    10921 tagtcttgaa tgtggtaaat gcctgacgcc actgagcaat gacttcgttt tggctgaatg
    10981 tttcttctgt aaggtaattt cttgcttctt ttgctgcctc attcaataat tgatgatacg
    11041 tttcttcact ttcttttgtt acgtggttat cgataccatt tacggataag atttcgatgg
    11101 ttgcttcagg aaatacttcc cagaaattgg tatccactat tacttttttc atctgttcac
    11161 acctcttgat tagaataatt gcttgatgaa tagatagtct gtttggggat catctcccat
    11221 ataaaaaaca tgttcgctgt atttgataaa tcctttttta cgataaaaag cgagcgcaac
    11281 atcgttgtgt tcccaaacac cgagccaaat ggctgttttt tgcttttctt ttgctttttc
    11341 aatagctgta tctagtaaaa atgtaccgat accttgatgt ttaaattttt ttcgtacata
    11401 gattcgctcg atttctaaaa aatgatcagc catttcctca gattgactcg ttcctgtatt
    11461 tagtttcagg taacccgcag gctcttgatc gatactcact aggaaaaaat cggtttcttt
    11521 atcttttagc tcttctgtaa gtttttctag tgcataagct tgtgtcaagt aatcagctaa
    11581 atgctccggt gaattatctt ttccaaatgt atctgtaaat gtttcgatac taatttgttg
    11641 tagtaagtct acatctgaag gcgtcatttt tcgaatttcg tatttattca cggcttcttc
    11701 ctttcaatag atccttttat tgcctttttt gacaaaattc caatcttcgc taacattctt
    11761 gcatacttta tttaaaagat attccaattg ttttgcttct tcgtcagaaa gaccatttaa
    11821 tgcgactgca ttggagtagt tgttttctcg aatgatgaaa ggatagattt ctgctccttt
    11881 tttagtcgga tagagtttct tgattttttt attttcttta tcttccaaac gttcgatcat
    11941 cccattggat tctaatttct tgattgctcg ggcagtcgtt gtacgatcta ctttgatcat
    12001 ttctgctagt ttttcttgga tgattccagg attttcgcaa atacgtacta aataaagata
    12061 ctgtcctctt gttaaatcga cttctttgaa ttcgatattg ctaatagaat ctagcgctcg
    12121 ggcaatcatt ccgatgtctc gaaggatttc agccatttca tcccaccttt attttgtttg
    12181 taagactagt ttacctcttt ttgttgcaaa tgcaactatt ttcaataaaa aaatcaagtt
    12241 cttttttaat aactagtaaa gtatattctt ttcttctttt acgaaaaagc tcaatcacaa
    12301 tagatctggt ttttgttttc taaaataagt aactgtttct tcgttgttcg cttttctgat
    12361 agctttggca actcttctat actaaaaaat cccatgttgg aagtttcatt attctcaata
    12421 aacttggcct cttcaccgtg gatcgcacaa gcaaaaacaa gtttataata ctgaaaaagc
    12481 tgtggaatat ctttttgttt attcgtatca aaaactgctc gcaactgagt agtttctact
    12541 gttaatcctg tttcttcata gacttcttta cgcacatttt cttcaggaga caatcctatt
    12601 tcagcaaatc caccaggaag tgaccattct ttcgtccgtt tatcttcgat tagtaggacc
    12661 ttgccatctt ttttgatata ggcacgaaca tctacttttg gtgttggatg tccttctcca
    12721 atcgttgtga gcgcttttat ttcttcgaaa gtttcttttc ctatttcact gatcagttcc
    12781 aatgaaatcg tccggatctc ctcaaaacgc tctttatcaa atacatcttt tccataatat
    12841 agaccagctt gagaaagtgc gagtagtctt ttgtattgag ccaacttctt gttcattctc
    12901 ttcccttctt ttttagcaaa tgtatgacta tgtaatcaag tatagaagac tggtttaatt
    12961 acggcaaata aatataatga aatctgcaat aaataaaaga atgttaaaaa actcgagaac
    13021 aaaagacatt cgacttctct ggggctgtga ataaatggcg ttcaaaagct tgcatctgcg
    13081 gtaataagcc ccaccaaacg aaaaatatga cgagctattc ttgtctggct gttcttatta
    13141 attgaggcag gacagctttt tcacaacctc cccactaaac ggtgttctcc taccaactcc
    13201 tcggtcacaa gtcacaatat tcatcaaaca tgagaagctg tttttttgaa attgctcctt
    13261 gtgactcgga gctgaacgac aggctcacga cctctcggta aacagcgttc aaaagccaat
    13321 ttttcgatat taagccattt ctttgttact tattgtcatt gatttctttt tctaatttat
    13381 ccaatagtgg agtgtaatcc acttgagtat agtctgttac atcaaattca tatagtgttc
    13441 ctaactggaa tttgtcatat tttcggtcgg cgatgatctt tttgaatgct tctttcgtaa
    13501 tatgattggt ccctttcgtt cgatcttcca atacgtcacc atagtgataa tgatccatga
    13561 tatagctcaa atgacgatct gattcacgat cacgtttgta ccgacgttga cataacactt
    13621 caaagtctgc tgttaggcga atcgtgatca cctgatatcc gtatctatct gctaattctt
    13681 ggagtcgtgc tttttgctta tcactaaaag gatactcgga cacaatcact ttctttcctg
    13741 cttccatata caaatcaagt gctttgtaat agaaaggata aactttcgtc ctttcttgtt
    13801 ccgcccgttc ttccaaattg ttaaacccga tggattctgc atagtattcc ttgatttcat
    13861 cgagcgtgat ggcatacata tctggaaatc gttcccgtag tttattcata agatatgttt
    13921 ttcctgtacc aggactacca gccagaagaa tgaaatactt tttcatctca tttatttcct
    13981 aagttaattg gactttccaa gttcataaac agtccaatct tatgcttgac aatttctttt
    14041 actgcttcat ttgctggaat cacattatgg cgaagagact tgttgatttc tgtttcacta
    14101 aaggtttctt tagctacttt cgtccagttg actaaaagct ccgttccaac attgaatttg
    14161 cggatcccgt tattgatcaa ttcaggataa tcttcttctt tcacacctgt tcctccatgg
    14221 ataactaggg ggacatcaac tactgcatcg atttctttca gcaagggaat gtttacttct
    14281 gtttttgatt tgaattgtcc atgattcgta ccgatagcaa tagctaatgc atccacgcct
    14341 gtagcttcta caaatttcac tgcgtcttcc ggtcttgtat ataccttgtc attttcagcg
    14401 acatggattc cttcttctgt accgccgatt gttccaagtt ctccttctac ggaaacaccg
    14461 tgcgcatggg catattctac tactgctttt gtcttcagga tattttcttt gaaaggcaga
    14521 tgggacccat catacatgac agaagtatat ccgctgtcga ttgcttcttt gatatcatca
    14581 aagtctcggg cgtggtctaa gtgcaagact gcatcaacca tttcttcttc tgcaatagct
    14641 gtcattacat tgactaacac atgcatgccg atatatttag cggtatcgac acttgtttga
    14701 ataatgatcg gcgaacccat ttcttttgct gcgcctagca tagcaggaag catttctagg
    14761 ttatgcgtat taaaagctcc aactgtaaaa ttcaactctt ctgctgtttt tgttacttct
    14821 ttcaatgttg tatacatctt ttattgccac cttatctttt tatttgtttc ctttgatcgt
    14881 tacttgtttt gcaatttgtc gcatctcatc cattttgccc atgtagtaat cgatcccttg
    14941 atcatcacca gcacgagcag catctgcacg cttctggtta tagaggctca tcagtttttt
    15001 atacccatct ccgatcgtct gtttattttc caaactcttt tctaaatatt ggatggcttg
    15061 atcgttcaca tacaattcag aaaatttaag tccaacttgt tcataaagtt tcgctaattt
    15121 atgcttatct tgggtagtgg aaatctcttg tttcaattgt gtaatctctg attgaatctt
    15181 ttcggtcgct tctggcgata gggctttttc ttcttttgcc agaacttttt tcggttcttt
    15241 ttcttttttc ttaaaaaatc caaacatcat tttccctact ttcaattaaa atgctttcaa
    15301 aactgggctt aagatccagg catataagag tgctgcggct actgtatcta catcggttgc
    15361 tgtagcattg atgaatccca tcgaattaaa gatcgttact agcaaagcgg gcaataatgt
    15421 aataaagaaa ccatgagcaa taccgccaat gatcgctcct cggcgtccgc caactgcgtt
    15481 gccaaatatc cctgctgtcc ctccggcaaa gaaattggtt agcataccag gtaaaatcat
    15541 cgctaagccg aacatgggca aagtaaacat ggcaataatc gtaccaatcg ttgtcgtaat
    15601 gaaacctaaa atgacagcat ttgggctata aggaaagaaa actggacaat ctaaggcagg
    15661 gatcgcatca ggaactaatt tcatagctat ccctcgaaat gccggcacga tttcacctaa
    15721 cagtagacgt acaccagcta gcaatacata cacacccact acgaattgga tggcttgtaa
    15781 aaaggcaaac atgatatagt tttgatctcc tgataattca gaagcgaatg gttcgcctgc
    15841 aaataaaaca gtgatgatat atagcgggac catcacgacc atgacagaca aataagtatc
    15901 ttgcagaaat tcgaaatgtg tcggcaactt gatatcttcg atcgactttt tattttcgcc
    15961 tttctcacca aaaagcttag caacaccggc ttcaaataag tacccgatcg tacaaaaatg
    16021 acctaaagca atatcatttg atccagtgat tttacgaatg atcggttgcg ctactgccgg
    16081 catagcaatg gcgaaacaag ctccgataaa accaccgacc aagatcaata cgatccctcg
    16141 cagaccggca aaatagccaa agactgtcgt catcgttgcc atccataaaa ttgcttgacc
    16201 agttaaaaaa atgtacttcc attttgtgaa acgagccaaa ataatattga atacaaaaat
    16261 ggctaagaac gtcagtgcaa tatctctacc taaacccaaa tcattcattg cttgaccatt
    16321 gatagattca atagaaggga tgatcccttg catatgaaat ccttcagtaa agattttccc
    16381 gaaataagtt aaacttccaa cgatgatgct cgaaccggca ctcaacactt gaaatcctag
    16441 gagtgtcttt aacgtgccag agatgacttg tcctgctgat ttcttctgca gtagtagacc
    16501 caacatagca atcaatgcaa tggtgatcga tgcctgagtc aaaatatttt cgatgataaa
    16561 attgataacg cccatgtttt taccctcttt tctttttgta tttagataac tcccttatct
    16621 tgcagaactg gggtgatttt ttcttcaatt tcattttttg aaacaatatt tttcaaatag
    16681 atcatcgccg ttttaggatc aactgcgaac ttttcgaact gcgaacgaaa attttctgct
    16741 gtgatgatca catctggttt catggaaact gcggaagaaa tatcacaatg gtccagtttg
    16801 gcttctactc ctaatttgtt caaaacatcc tcagcagaca tctgtgctgc aaaactactt
    16861 cctaaacctg caccgcatac gaataaaatg ttcaatttgt tcatctttgt tctcccccgt
    16921 atcatttatt atttctcaac tactgaaaaa agcagttgtt tgaaatcttc gatatttgtg
    16981 cattcaatca atcgatccaa cttctcttcg ttgttgatca attcaattag ttctttcatg
    17041 atgttcagat gcgagtagga gtctactgct gccaaacaaa aaataatctt tactggatcc
    17101 atttcaggat taccgaaatc gattggttgc tcaatcgtag ctacgctgac tcctaattta
    17161 ttgaccccat cttctggtcg ggcatgggct agtgccatgt gtttgccaat cacgatatac
    17221 ggtccgtaat cattcactgc acgaatcatc gcttcgacat agcgctcttc gacaatgttt
    17281 tctttaacca atggtctagc agctagttca atcgattcct cccaagtagt ggctttttct
    17341 ttgatcatga tattgctgtc cgtcaaaata tcttttaaca taggctggat ctcccttttg
    17401 ttgatttcta aattgtttgt ttcgaataat ttttctaact tgccatagat gattcgatct
    17461 actcggccac cactttcttt catgacatct attatttgag tgaataactc cgtcgattca
    17521 tgactgttag gctctaaccg ctgtagttct tcatttcttt tcaaaaagtc ttctataacc
    17581 aagatattcg tctcagttaa aatcggatcg acaactaaaa gcggcttatt tcgataattc
    17641 aattgaaagg tgctgaaaac cagattgaca tccaatttat ctactaattc gatttctttt
    17701 gaacttaaaa ctgcagtaat ctcgatctga ggaaactttt ctttcagatt ctctgctaac
    17761 agatttccag tagccatccc atggttacag acaacgactg atttataaac ataattcaag
    17821 tctcgcttga ttacactggc gatcgtcgaa aagtggatga caagaaaagc tatctcgtcc
    17881 tccagtatct tgccaccaat tacttcttcg atcgtaggaa caaaatgagt gactgcgcgg
    17941 tagattggga aataatttgt tcggatgttt tctttcaatg gattcatgac ttggatatga
    18001 ttcttgattc ttacaatcag tgcagccatg tgcttataga gattttcgaa taaagcttct
    18061 tcctttagat ggaaaggtac gtgtgtctcg ttctctacaa attggatcaa ttggatcgtt
    18121 agtaattgag cttgtaccca ctcgattgaa ttggagatat ctctagcatt gaacgtctca
    18181 atagtgaaac gaagataatt tctttctact tgcgggacat tgtccaattg aaattcctcg
    18241 atcatgtggt caataaatgc agaaaagcta ctgtctttta tttctgtatt tttccaatta
    18301 atggcagaga taaattcatg tttcctgatt cgctggatcc agatcaatgt aaaaagcagg
    18361 atttgttttt tataaatatc atcttcttgt ttcaacaact tattggaata gatctcctgt
    18421 atttttttga tttccaccaa aggaaaataa tggagaaaga ttttttgagc cggtgttaat
    18481 tgtgcatctt gattcataaa gaagtcggtc attcccagat tctgattgat aaaatcatag
    18541 atcatcgtac ggatagatcg ttctgaacct ttataaacca gtccttgctt tccataactg
    18601 acgatctcta tcccataact gaccagtgtt gctcgtaacc gtctcatatc ttcatctaat
    18661 gtacttttag agatttgaaa ttcttcttct tttttgttta gatggatcgg gattcggctg
    18721 taagcaacgg ctaaaactag atcaaaaata cgttcgcgcc gattcaaaaa gccgtctttc
    18781 acatctttta tttcagtttc taatcgagct tgcttttcct tttccagctt caacaaaaaa
    18841 actttgttgc gaattgtacg gatctccgga agctttttac tgctcaacca gatattcgct
    18901 tcaagaactt cctgacggat cgtccgctga ctgacattga actcacttgc tagatgtttt
    18961 gcttttactg gatattgggc tgtcatgatt ctgtgaagta tttcaattgt tcttgttttc
    19021 atagaaatga tctccttctg atttcaagta tatggttccg cttacataat aaaaagtaga
    19081 tatttctgcc acttgaagtg gaaagaaagt aagcaaagca aacaaaaaat aagccatatg
    19141 ctttttcatc tcctcaacga aaaagacata cgcctattat tacaaaaatt ttgcccatct
    19201 atacaaaaaa gaggttgtga aaaagctgtc ctgcatcaag taataagaac aactaaacta
    19261 aaatagtgct tcctattttt cgtttggttg ttcttattat cgcagatgca agcttttaaa
    19321 caccatttag tggagaggtt gtgacagaga tgttcagcct tgagcgataa gaagcgattt
    19381 tgaaaaatcg cttcccatat tttacaaaat cgtgccttat tgccgatagg ctatctctgg
    19441 cacactgttt attcagaaaa aggagctgcg acaaggcttt tgtcacaact ccgttcataa
    19501 atatttcctg tcaatccagc ataatcggct gaataaaatc ggcttgccat cttttttctt
    19561 tctcagaaaa atcaaaatac catatctgag aaaaatactg tcgttgtgtc ttacttcctg
    19621 agatcaatcg cccatctttt cgatcgactg aataatcaca gcatctgaaa tcaattcgga
    19681 tggcaaaact attttcgtgg atctgtcgat aatttcctac ttcctgaata gttatttttt
    19741 tagtatgatt tcttacaccg tctgctttgt ttttttgcag aactttctga tgttcggcaa
    19801 acagcttgtc tgtataacag cttctggctt tttcaggagt ttcttcttcc caagcggatt
    19861 ggatcttcat gaatatcttt tggatttcca gaaactgtgc tttcttttct ttagccgttc
    19921 ctgacatgcg ggacaatatc tccgctttca gccttttctt ttgtctttta ttcttgacga
    19981 tagaaaaagc agaaacccct cctactgaca aaacagctaa tgcaagaaat cccgtttgct
    20041 cataactaga aggacctgta cctggaccat aatacccata agaatctctg ccgtaagaac
    20101 gactgccaaa ataactgccc ccatatgaac gaccaccaaa tgaacctctg cccgaacttc
    20161 gaccgctaga tgtacctcca ccatgaccac ccgcgacagc gaatccttgg gtcggcagag
    20221 caaacaaaca taggcccact aacaaaatga ttgctaaata attgattttt ttcattgtct
    20281 tcctcgttat cttttattac aaaaaactat ttttatgata gccttgctaa aaggaagagt
    20341 caataaccag atgcataaac tgttttttta gcaattttgt cttatttagt cattgagtaa
    20401 catcggacaa atgtatgtgt cggcagtcca taattcctct atcttcagca tgaacaagct
    20461 tgcagacaag agatctgcgc ttcctccagg agagatttgg ttttcctgac aaaagtgcaa
    20521 cagtgctgta aatggacgat ttggtaaagc actttgacta gcagcatgag caagtttttg
    20581 catttccact aacgttttct gatcactgcg atgcaatacg catgtgtcat ctagcgaact
    20641 catcaaaact aacaacatat gcatttgttt ctgtacatat gaatcattat ctagctcctt
    20701 agctgcttgg attgcaagcc tgatatgcgg ataccctaat atcgcttctt catatgcacc
    20761 atttacgcca tatttttgct tcaccctatg accatgagtg gtttttttat gacgatattt
    20821 tgtatcagga aaagcagcaa gcttgctgac atcatcaagt attttcgata aagaaaaagg
    20881 ctgttccata ctgatttttt gtgcaatgac actgatcaat agccccattg cccaaatcgc
    20941 tcctttatgg gtattgatgc catttgtagc aatcagcatt gccttttccg cttttcgccc
    21001 aatctcagca attctttctc ttaactcctg atcaatagca tgatgccatg ctatttgagc
    21061 catttcttca aaaaaaggag ttagcgtctt agcagactta agaaataaag catagtccat
    21121 atcggaatgt gcacccgcat ccagtgcatc cactaatcca ggttttggac ttaatgttac
    21181 ttctgcgatc aatgcttcct ctaccaacgc agcgagttgc tgagtcactg ctttttttcg
    21241 ttcgtcattt atcatgacac tcactccttc ttcctactat tacttgctga aacctttttt
    21301 gatagctacc caaatgatat gaagtaacca gcttaaagca aatgcacaac ttgccgtcat
    21361 tagataagct acaagaatca tgactcctga aggtaactgc agccaactat ctttaaacaa
    21421 taataacagt acttggaaaa caaatacatt ggctaaatac gtacgataag cataaacaga
    21481 caaccatttg aacaatggca attttggcga atcgtttaca atcattttgg aagcgcctat
    21541 gaagacagca aagatgatga ctaaactgta taaactttgg atcgtattca agtaaggtgc
    21601 attcgcaaag ctcaagtctc ctggatgtgc gagcaatgaa cggacagaaa agaacgcgat
    21661 aactaaggca acaggtaaga aaagataacg tactctgtcc aaatattgat agactttttc
    21721 gtgataaaca aatgcggcta ccccataaat catgaaacta gcaacaaacc gatctaataa
    21781 gtaccagctg tcatgataag gcccagtcaa tacttgtgtt tgatagaaca gataccatgc
    21841 gacatataaa atcgttgaac caatcaatac tggccataca tattttttat tagcaaatac
    21901 tttgtaaccg agccaaacaa aaaacggcat gaacaattgg atctgcagca tcataacggt
    21961 ataccataaa tgaggcgctc catcacctgt gacatatttc agtaaaaagc ttgcagtatc
    22021 cgtatacgga gtttgttgtt ggactgctgg aaatagccaa agataagccg tcgtccatag
    22081 aagatacgga acgactagtt caaaaaactt ttctttcaaa aattcccaat aagacaaatg
    22141 ctgacttgtt tttaccatat tataaacaat tgcaaaaata aacattggtg ctgtgtattt
    22201 aacgatgacg taaaaggtac caagaaaagc tgtatttgtt gcgctgtggc tgtttgccaa
    22261 agcaaagctc aatatcgttt gcatcataac agccgttaca gctgatactt tctggaagtc
    22321 acttacgttg attttgattt ttttgttttc aaacatctct ttctctctct ttttctttat
    22381 taccaaagtt ctttggttaa tttaggtcct tcgactgttt tcaatagaat ttttttctct
    22441 ggctctctca aatactcttt tagtgaaaaa ccgccttgcc gagtcactac ttgggtatcg
    22501 aattgctcaa aaaaagcagg atgcgattga attacctgaa ttggcaattc aatcggtgaa
    22561 tttgcgtaca gcagcaaatc aaaatcactg gtttctttta ctgccggaat cccagtcgat
    22621 aattcaaatc ctaagctgcc gccgattccc catttacatc ctgataatat gtttctagca
    22681 gcatgaaatt gctgataaac aggataatcc atgattttct cttgtctata cgattcttgt
    22741 tcgatgatgt cccacggatg aatgacttgt ttgacggcat gttttgagat ttctgttgac
    22801 catctctgat tgcgggcagg tccacgtaaa ccaatcggta gtatttctgc gtgatccgtc
    22861 gacgcacgac gaactgttcc gaacatcttt tcagttagaa cgacccattc aggcaaggtg
    22921 aacccttcta tttcatgttt atcaaaaagg acaatatcat gtgcttgaat cattttttat
    22981 gcatcccatt cttcgtccat tttggcacgg actttatttg tttcgacacg tccgaatgtt
    23041 ttggctgttt cgtttgtgta tcgatttgtc agcatcgtgt catttgtatt gcggacatct
    23101 tgaatggctt cattgattgc ttcgatgact ttgctgacat tttgttctga agcagcttgg
    23161 tcggtgatat cttctaggaa atgatagatc gctcctagtt ttgtataatt attgatatcg
    23221 taagcgatag ctggaacttt ttcagcagct gcttcgattt cagcaaccga acgttttgtc
    23281 acacgtgcag cactttcttt agacatcgct tggacggtaa tttctttatt gtttaaagca
    23341 atcaagcggc ttgattgtaa tccatgtgct aaaaatgcac ctgaaatagc atttcctgca
    23401 atcaatccaa taactggatg tccagcttga cggagttttg cataagcagc agcactatta
    23461 gccaaagcca catggatacc gatcaattct tcgttatagc cgtatgcttg gcttggtaca
    23521 tcgatcacaa cgatgattgg ccgtttcact tttttgtctt tatcttcttc gtaaacgtga
    23581 tccaaaattt gtcccatgcg gaaaccttca actaaaccaa cttcaccgtt tcgtacacgg
    23641 tacatcgggt ttttaggatc aggtacgatt gatgtcacga tggcttcttc tatgaattta
    23701 cttgatttac cataatacac agtactaata gaagaagttg gatttttcat gccagttagt
    23761 gccgcaaacc aatcgtaacc aacacttgct gcagctggtt catttccttc tgctacttct
    23821 ggtaagtcaa ttgattttgc ttgatggtta gcaattgctt cattgtaatc gtcaatggcc
    23881 attggttttg aaagatctaa agaatcaagt aatgataaat aaaatgctga gctttcactg
    23941 cgatgcgtgt cttttcgttc gtccattgct gcgatgacag cagctttgat tgcttctaca
    24001 ctatcagtca ctaattcatc aatgattttt gattctaccc gttgacgaga tcctaatgta
    24061 ttccaaatca agtctttgtc actagaatca aattctcgaa cgcctgcttc ttgttcaata
    24121 acttctggtc cattcaaacc gactctcgct ttttttgttg cgattaaata actcattaat
    24181 gctgaagtaa tcgacatacc gccaaatgat cctacacgtc ctggaatcaa accgatgact
    24241 ggtacatatt gttttagagc aatgattaca tttccgattt ctgaaataga taacagtccg
    24301 tagtttgctt cttgcaaacg aacaccacct gtatctagta caatgactgg aaagatctca
    24361 tttccttttt tattttcttc taacacatgt tcaagtgcag caacgatttt tgcaccggaa
    24421 acttcaccga taccgccacc ttggaatttt ccttccatag cgattactac tgcttgtttg
    24481 ccattgatcg tgccacggct gacaacgatc ccgtcatcac tttcagggac gattccttgt
    24541 gctggtaaac ttggcgcgat gatttgatcg aatggatcaa tcaattcacg tccattgtca
    24601 agtagagcgt tcactcgttc tctggcgttt aattctacaa aactattttt catctgaaag
    24661 ttcctccatt gcttgcgtca atcgtaggta cacaactcct ggtgtagcac cgaagtcatt
    24721 gatcacgata tctgctgaaa ttggataacg atcaaaaaat ctcgttaata cattgttcca
    24781 tacttcgccg aagccatcgc ttcctgtaca aatttttaca gtagattctg ttttttctgt
    24841 tggaaacatc aagatttcca aatctcctga accgaccact cctacatgga ttttcttatt
    24901 gatcggctgt ttcgttggat atttataagc taattgttcc atggatctct cccctttttg
    24961 taaaacagag catacacgtt ctgcttattc gtctttcttc ttccatctgg gtaaatggcg
    25021 acaaaaggtt tttctcgcca attttatgac caagttctga atttcattgg tggttcatac
    25081 aggccatctg accattcgat caaatcatcg atggtttgtg cagctaataa tgaacgtttc
    25141 gcttcactac gtttgatgcc tagatcttct ggtaatttca cgatgccggc tgcacgcaag
    25201 ctatctagtg attctttcgt gctagtcatt ccaagaggtg taacaccgcc aattgctgca
    25261 attgctgctt gtcgttcttc ttttgttttt gctttgtaca aataagcaat tccttcttct
    25321 gtcacgatat gtgtagtatc ttcgctataa atcatcactg gtgcattggc taagcctgct
    25381 tgtttttgaa cagctagtgc atctaattct tcgacaaaga ctggtttttt atttgaacca
    25441 tatgtttcaa ccatttgaac aactaatttt tggcctttcc ctaatggatc atcattgtcg
    25501 cgaagtgatt gccatgctgg tgtagaatga cgacgaccgc caggattatg tcccatgtta
    25561 ggcgcaccgc caaaaccaga taaacgtcct tttgttacgg tagaagagtt tccttcgtaa
    25621 tctaattgca aggttgaacc gataaacata tcgatggcat attgtcctgc agcttgtgat
    25681 aatgttcggt tactgcgcat cgtgccgtct ttaccgacaa aaaagacatc tgggcgagca
    25741 gcaatatatt tttccatacc aacttcgcca ccaaaactat ggatgctttc aacccaacct
    25801 gattcgatgg ctggaatcat cgttggatgt gggttcaata cccagttctt cgcgattttc
    25861 ccttttaacc ctagtgattc accataagtt ggcagtaaca attcgatagc tgctgtattg
    25921 aatccaatac cgtgattcaa agattgtacg ccgtgttctg cgtagattcc tttgattgcc
    25981 atcattgcca ttagaatttg caattctgtg atgttttgag gatctcgtgt gaataaagct
    26041 tctaattgat aaggtttatc tgctttcacg acaacgtcta cccagtcacc agggatatct
    26101 acacgtggta aagaatcgac aacttcgttg acttgaacga tcacgatacc atctttgaaa
    26161 gctgcagctt cgatgattgt tggtgtttct tccgtattga aacctgtgta caagttgccg
    26221 tctttatctg ctttatctgc agctactaaa acaacatttg gaatcaaatc gatgaataag
    26281 cgtccataaa gttccaaata agtatggata tcacctaatt tcattgtgcc gtcttcaatc
    26341 atttgggcga cacgcaagct ttgtgcacca gcataagaga aatcgatctt gcttgcgatt
    26401 cctttttcaa aaatattcaa atgttctggt cgtgagatac tagacatgat caaatgcaga
    26461 tcattcactt tttctgcatc tactttttca agactttctg aaagaaaact tgcttgtttt
    26521 tgattgtcgc cttctaatac aactttgtcg ccgggagcaa tcagtttttc cattacttct
    26581 acgatttttt cagtttctac atacttgcca ttgagcaagt tgctgatttt ttccaatcgc
    26641 tgcgcttttt tttcgcgttt agaagcccag ttgcggtttg gtttttccat aattagtcat
    26701 ctccattttt gatatagaaa cgtggcgtca tcaataccat gttggtctag attgatcgta
    26761 cggatccctt tatctacacc aaattttgta tgaatcagct ttgtcaaagt attgccgggg
    26821 ggaaattcaa tcgtcagatc cattcctaat tcttttgcca agtccatcat ttggttccac
    26881 tgcacaggga aagctaggtt ttccaacaaa tctttacgaa tctcttctgc gtcctgagtg
    26941 gctcttccat ccgtattttt tatatacaaa catctagcat cagatagatg gacagactgc
    27001 atatacggct tgaatttctt gaccgtatca ttcatcaaga gacagtgaga tggcacaggg
    27061 actttcagca gcttcgctgt ttgcgcttgg tgccgtttgg cttctgccaa cgtaacggat
    27121 aaaccttcga tactcccaga taacgtatgt tgcatcggac aattttcatt tgacagataa
    27181 actggatggt caggatcaaa tgtttttgct acaatttcct cagcttcgct tctcgtcaca
    27241 cctactacta cgcccattgc ataaccgctt ggataagctt ctttcattaa gactgcgcgg
    27301 tgatagacta gttccgctgc attctcaaat ctcaaagatc gacaagcaac agctgcacaa
    27361 aaagcaccaa tcgaatgtcc tgctgcaata tcaggctgaa taccgttttt ttccatttca
    27421 tctaaataaa atactgcttt tgtcagtaat gctagctgga taaaaaccgt atcttgatag
    27481 ttttcttctt tatcaactaa ccgatacccc gtcacatttt ctaaacgttc catgtacatt
    27541 tcagggatat ccgctaacat ccctaacttc tgactgcctt gtccaggaaa taagaaacct
    27601 gtactcatga gcctcgcctc ctcagcactt actttttcca ctgctatctt agtcaatttc
    27661 tgctataata aaaaatgcca aaaaaagaaa aaaccataac aaaaaggtat ggatgggatg
    27721 gataattatg aaattgcttc atctgcagta ttttaaaaaa gtattcgaaa caaaaaatgt
    27781 tacccaagca gccaaagaat tatttatttc tcaacctgcc ttgagccgtg cgatcaaaca
    27841 tttggaaaac gaattaggtg tccctttgtt ttaccatagc ggcagaaaca ttgagacgac
    27901 cgtttatgca gaagaatttt atccatatgc agtcaagaca ttagacacat tagaagaagg
    27961 aatcaaatta ttgtcttcgg tcaatgagaa gatcgttact tccgtcatat tgtatttaga
    28021 ggtagcctct gtttctattc cgaacttggt ccgaattttt atggaaaagc atcctgatat
    28081 ccaattaacg atcatgcaac atcatttacc agatgatatt accgatcctg tactgtacat
    28141 cacttcggag atgaagcctg gcatgaccaa tattcctatc atgaaagaac ctgtttatgt
    28201 cgccattcct aagaaacatc ctcttgctaa aaaagaacat ctgcaattag aagatatcca
    28261 acgcaccccc atcttgatgc tgtcaaagag caacgccttc cgtcatacac tggatgcagc
    28321 acttgaagcg aaaagtatcg aattgacgat cagttcgacg acagatgatc ctgcgacatt
    28381 acgttctatt gtcaagcaag gattagctgt tagctttttc ccaaaagttt cttggtctta
    28441 cgataaaaat gatcctttcg tcttgcggga aatcaaagat ttgcccttga cacgaacaat
    28501 ttatttatct tctagcttca cagaagatca tcctttgatc aaaatgattg caaaaacgat
    28561 gcgggaattt tatttaggaa aataaaaaaa aaagagctgg gacaaaattc ttgtcgcagc
    28621 tcttttttcg aacaaacggt gttccagaag taatttctta gaaaataagc cgaaatttcc
    28681 caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct aaacatttct
    28741 gtcacaacct cttctctatt gtcctagaca ttcattgcgt tgatttaaaa cttccatcaa
    28801 tcaaatctgc tagttcatct agcttttcta ttttacgtag atcaatagag atccaatgtt
    28861 ctttattcat gtgataggct ggaaaatacc cctcttttcc tcgcaaaatt ccgccaagtt
    28921 caggatcgac cttcaaatca agaatattga tgatcctatg gtcacttgca tcatcataga
    28981 ttttttcttc tggaacagac atcaggaccc caaaccattt tttgcttttt tgatgtctga
    29041 atacgcaata atcaggaaat tttttaaaaa tatattctgg agacaaattg tatgtttcat
    29101 tgatgtgatc gattagttct tttttcgtta gcatctgctt ccatctcttt cttattgatt
    29161 cgctttattc aaagatacca cgtaagaata gaaaaatgaa tacaagtagt tgctaatcaa
    29221 atacttcgat atttttcttt tttatcaact cttaaatgtt caatccgcct gtgttggtct
    29281 tgctaccatc tactattaaa atgtttatta ttgtttgccc acctattttt tgattttagt
    29341 ggtatcattt ttcaagttca tgatgaaatt cttatcatca gtaaatgctc cagaaaaata
    29401 aacaatgatt gaaaaatcag ttgaaacttg accaccgttt attttctccg tattcttaga
    29461 atagaaggga gtctgattga tgtattcact aatgaaaaaa atcattaccg aaaaagatat
    29521 tcgacgtcat gtttctttag tagaacaatt gctgaatcat acaaagataa ccgtaaatga
    29581 attagctgaa atcataggga caaccgaacg aacgattttt tctgaccttc aatctattcg
    29641 ctctcagctg cccgaaggct gggacatcat cagcgatcaa gcaggaatca gtttgcaaaa
    29701 ccagcaaaat ttattaacaa atgacctttg ggagattttt ttcaaacaat cagtcagtgt
    29761 cgaactgctg aaaaatctgc tttttacaaa aaaagttgct gtccctgatt ttctagccga
    29821 ccatgggctt tcttatggga cattgaaaag acatgtgact aaaatcaatc agcgtttagc
    29881 aagttacgac ttgcagatcg atttgacgaa atatacagct tgtattcttg gaaaagagcg
    29941 tgcgattcgt actttttatc atcgattgct gattcctttc actcataaca actatttttt
    30001 cgaggattat tcgatccatg aatcccatta ttttcaattt ttaagaaacc tcagtcaaac
    30061 tgaactagcg gttgaaacag aagagatttt cggaacatgt tggttcttta tcaatacgat
    30121 ccgtataaaa gcgaattgcc gattagattc ttctatccat accaacagca cactctcctc
    30181 cctgtatgac tctgcattga aaaaattgta tttaacggaa ggtatttatc ttaaagacac
    30241 tgagctttct tttgcttctt tctgctttct ggaaagttgg aattacaaca ataactatgg
    30301 acaagaaacc gctcgctgcc tgcatcattc tccattttta gaggtcctcg aaacgtttgt
    30361 agaggaacta gcttcagagc tgtctcttga tcaactaaaa aaaacatctc tgactgataa
    30421 cttggctctc ctcatattaa aatatcatga atcgccgata ttgattgaag cattggaccg
    30481 tcaataccat cgttttttag aaacatatga tcagcaatat gcacacttgt atcaacagaa
    30541 agagaattta ctgaacgatc taaaaaaaga aatagaaatc aatgaaccaa attactttct
    30601 ccaactcttg tctctactga tccaacaaac gattttttct atcaaaccga atttgttcaa
    30661 tgtctatttt attttccaag gagaaccttc atggaaggcg ttcttgcagc aggaattaaa
    30721 agattactta ggaaaacgtg tctgcttctt acctatcgaa ctaaccgatc tttccactat
    30781 ttcttttgaa aaaacagata tcttgatttc caatttccct ctagattctc tagatatccc
    30841 tattgtatac atttcttcta ttccaacgaa aaatgagctc aatcgtttga ctgaactcac
    30901 tttcaaaact tttttatagt aacggctagc gactgtattc tctagctgtt ttttcttttt
    30961 tgcgaaacag tttgttcatg atcccttttt ctatttctac aactaagaat agaagaatca
    31021 catttgctcc aatcaataac tgttgtgtca tcgttaaact tactgtaccg atcagctgct
    31081 ggccgactgg tagaaaaata accatccctt gcaataaagc aaggatacct aatgaaagaa
    31141 aaagcgcttt gttttgcaaa agaccttggt tcaatgacgg cttggacaac tctctgcaat
    31201 tgatcatgta aacagcttga gctaagacga tattttgcag aagaatggtt tgctgtaagc
    31261 tttgcccttc aaactgcata gccaataaat aggcaggaac catgatcagt agggagacat
    31321 agatgatccg aaacaaatga taaccagata ggattccttg ctttggatct cttggtgggc
    31381 gcttcatgat ttctggatct ggcgactcga accctagtgc ataagataaa gtgattgtcg
    31441 ttaccatatt gacccataaa atctgtactg gggacaaagg tagcgggcga ttcagcataa
    31501 gtgcccaaat caagatcaat ccttgagcta atgcagttgg caagaagaaa ttgatggttt
    31561 tttgcaaatt atccaaaatc cgccggccct cttttacggc ttttgcaatc gtatggaaat
    31621 tatcatctcc taaaaccata tcagctgcct gtttgcttac ttcactacct ttgattccca
    31681 tagcaattcc tacatcggat cttttcaaag caggtgcatc atttacgccg tctccggtca
    31741 ttccgacgat ttctccattt ttctgcaaag ctttaacaat tcgcagttta tgttctggtg
    31801 tcgttcgagc aaagacatcg actattggca cttgctgaat caactcttca tcagacataa
    31861 gatccaaatc gatcccttct aaaactttgg cagtatgttt taagccaatt tgttccgcaa
    31921 tcgcttttgc tgtgtctttg tgatcccctg taatcatttt cactgagatc cctgcttgtt
    31981 ggcattcctt tacagctttg actgcacttt cttttggcgg atcgatcaat ccggcgatcc
    32041 ctgcaaaagt taattgggtt aaagtctcat gcgtgagttc ctgtttcgaa tctacttttt
    32101 tataagcaaa tcctaaaaca cgctgacctt ttctcgcaaa ttctgcagct gtctgactcc
    32161 atgcttcttg ttctgcagaa gaaagagttg atttagcaaa taatacttct ggtgcacctt
    32221 tgacgtaaat caccgctcct ttttcctccg catgcatcgt tgccatatat ttgtattcag
    32281 aactgaacgg aatctttgct tctatttttt tcaaaggtag attggctgtt tctgtgtgtc
    32341 gaatcagcgc aacttctgtc ggattgccac ttaaattttc tgttttctgt tcttcttttg
    32401 tttttaattc ctgacagttt ttcataatgg acaacacgca ggcttcttct tttgcagcta
    32461 catccacaac tgtcatttca ttttttgtca atgttcctgt cttatctgaa cagatcactg
    32521 tcatagaacc taatgtttct accgaaggaa gtcctttgat gatcgccttt tcttttgcca
    32581 tttcatgtac tccaacggat agaatcatgg tcaaaacagc tggcaatcct tcgggtacca
    32641 ttgacaccac caaagcaatc gtagccgaaa gaaggatatg ccaatccata ccatatcgaa
    32701 atgtcgtaaa aataactaag aataggctca aacaaagaat gccttgaaaa atttgtttgt
    32761 ttaatcggtt gattttttta atcagaggcg tcgtttgttg ttcgaccgat tgcaatgctt
    32821 gattgatttt accgatttct gtcgtgtttc ctgtttctac aacgacaccg actgcagaac
    32881 cagattgtac aagcgttcct gaaaaagcca tatttttctg gtcgccgatc gattcttctt
    32941 ctgtcaaaac ggcatgactt ttttcagatg cttctgattc tcccgtcaaa atcgattctt
    33001 ccactaataa atcatgtgct tcgattaatc ggatatctgc tggaacgaca tctccggcac
    33061 gtaagacaat gacatctcct tttaccagtt ctttcgcagg gattttttct tgcatcccgt
    33121 ttgatagtac tatcgcttct tgtcccatca gctgcttcaa accattcaat gattcttccg
    33181 cttttctttc ttgccagtaa ctaacgagtc cattgacgat cactacgaat aaaataatac
    33241 ttccttcaat atattcacta gaagcaaatt tcaaaaaaga ggcaatgatc aacacgatca
    33301 tcagcagatc agtaaaatgc tttgctattt ttttccatcg ttttgtctgc tgccttgctt
    33361 ttatttcatt atatccttga tcagtcaggc gtttctgtcg ttcttcttgc gacaagcctt
    33421 ctgttgatgt ttgatagttt ttcaatacat cttctaccgt caatctgtac cagttcatcc
    33481 tatcccctcc tgtttaattg atactgttat tatacgcagg gaagtttttt caggcgtatc
    33541 gattatttca ggggggtctg aaataattcg ttttgcaaaa tgtatctggg cctaactgat
    33601 atttctattg cttattcttt tatatacaaa atttaagaat acaaaccaga taaccaataa
    33661 aaaaggaata aagcgtgtcg tgctttcgaa taacaagctg aaagcaattg aagtaaaaaa
    33721 caccaacaaa gcaagatctt tatatctttg tgtagtgttc cgtttctttt ctttaataaa
    33781 ttgaacatgt gcacacaaga tcgaagacca cacaaataga aaacaactcg ttgtcatgcc
    33841 tgccaaaagc tgaaaaaaca atcgactatc agctacaaaa aaatgtagac aaagaccggc
    33901 aaaaaataac attcctgtaa ttaaaatacc gtgtaaaggt acgcctttct tagaaagcgc
    33961 acaaaaccaa tggggcaaac ttttttcttt tgctgtttga tataaaatcc tgctagtact
    34021 gtagactgca ctatttgctg aggacaaaga agcaaccaaa atcattagat tgacaattgc
    34081 tgctccgcct tggcaatgga tcacttgcag catagtcact aaaggacttt cttttaaatc
    34141 taaacaatgc catggaacaa caaataaaat cgacaaaatc gttcctatat agaaaaagag
    34201 aatacgccaa ggcagacagt tgattgcttt tttcaaattc ttttgcggat cacttgtctc
    34261 gccaacggtt aagccgatca tttcaattcc agcaaaactg aataaaacca taggaaatga
    34321 gactaccatt ccagcaaagc caaacggtag taattcatcg atctgtccaa aattttcttt
    34381 gattccgata gactgggtat gaaaatctga gacactcaat cctataccca ataagataaa
    34441 aaggaaaatc cccaagatct tgatgattga gaaaaaagat tccaattcac caaaccactt
    34501 gactgcaaca aggttgactg ccattaagat cattagtgcg ctacctccgc ttatcaaagc
    34561 tggtacatgt acaaaccaga aatggatata caatcctatt gctgttaatt ccgcaagtcc
    34621 agctccaagc cagcaaagcc aataagtcca attgacaaaa aatgcccact ttttgcctaa
    34681 ataatagtca acgaaatcac tgatagagtt aaatgtacta tttgctaaaa ataaatcacc
    34741 catggcccgc atcaaaccat aaatagccaa accgcatatc aaataaacga gaataacagc
    34801 tggccctgct gatgcaattg cctttgctga acctaaaaat aatcctgttc caattgcgcc
    34861 acctaatgcg attaactgga tatttcgatt agttagagtc cgtttcattg ccggtttttc
    34921 catcaagttc acctttttct ttttcaagca gcatggcgac ttcctgttcc caagaaggtt
    34981 tctttatttt ttcaatacag agtggtacta caaacaaaat gacactgatg gctgtgactg
    35041 caattagatt gatccatgtt ccagctttca tcgtcagtcc gacagaaaat ccgattgccg
    35101 caaataaaac aataacgaca gtccaaactc caagattgct ctttttctct ttttttccaa
    35161 ttctaaatgg tcgattcaac tttgcatgtg tataacgcaa tctcaaaact gcgatcccca
    35221 tgatgacata gacgatacag tagataacag tagttgaatt tacgagcatc aaaaatgctt
    35281 gattgacgcc aggaatcagc aaataaaaaa gtgcaaagat tgagataatg acagactgag
    35341 tcaaaataac ggatttggat acgtcaaatt gattcgtctt ccaaaaattg aattttggtg
    35401 gatacgcacc ttttctagca ctttctgtca ctgtctttgc tggtcctgag gcccaagcag
    35461 ataattggac tgctacacca atgaagacaa gtaaactaaa cagattcaca ataagatgtg
    35521 gcaaaccaag aatttggcaa taaatcgaaa tagattgcgc gatattattc aattccattt
    35581 gtccttttgg tacgacattt gctacaacta aagcattcaa aatattgacg aaaaatataa
    35641 aaattaacgc ggcaaatact ccgcgaatat acgttttaac tggattttcc aatcgagtga
    35701 tatacacaga ggacatttcg ataccagtaa aaataaacat gatcggcgca aaataaacaa
    35761 atgaggatgc agtcgtagta tctggtatta atttgtccca tgaaaaactg cctaatgttc
    35821 cggttggtac gatcccaact ttgatccacg cagcaaaccc taataagagc atcatcgtca
    35881 aaggcacgta caatcctaac caaacaccga cttttccgcc gatttttgcc atatcaaatt
    35941 tcaaattcaa aaaagtgatg atccaataaa cgactaaaat gacaactaat gtaaatttgc
    36001 tgttcaaacc aagcggcaca ttatcgataa tattaccaaa caacggagcg agtgctgaag
    36061 cgaccatcac catcccagga aacatttgga cccataacag ccatgagaca acgaaccccc
    36121 atttttttcc tagagcattc gatacccaaa gttctggacc acctttttgg ggaaacattc
    36181 cagcaaattc accagagatc aatgagattg gaaaagcgta caataatact gcaaccagca
    36241 tgtaaaaaat catcgtccag ctcgttgctg ctacatctgg aatatttcgt acacttgcta
    36301 caagggcgca ggtcattccg ataaaggtca tggtcgtgat ttgctttgat gaaccagtat
    36361 ctttcatctt tattccttct ttcaatagcg acatatgttt ttgttttctt ttatttttgt
    36421 tcaagaacag aaatgacaag gtttcatcga ttcagtacaa aacccagtat caccgaaaca
    36481 tccattgaac gatcttagtg aactgggttt gatacatgaa acgaacgatc caacttatag
    36541 aacgttttat aaaaaagaat atcttggcga ggaatatatg aaaaacaggg ggaaatacaa
    36601 ttgttttgat gaagcaaata attgtctgtt ctccatatgt ctcttgttat tctttcacac
    36661 aaaaatcagt tctattggat gatttcgttt agtttctttt ccattgcttt ggcgattttt
    36721 tttgtataaa aattgaaaat tcgatcatca ttcaaataag gagtcatgat agccgcacgt
    36781 agcagagtga ttttctgttc ttttttccat tcttctttcg ttagacccat tctttcaaca
    36841 aaacgaatcg gagaatcacc gtaatcttct tgtgtaaatg tagtatgaga agtaataaac
    36901 cgttcaccat aaacatcgcc atccatataa gaagaccgat cgaacatttt ttcatttaat
    36961 tcattgatag cgttcaaatc tgtacagcct tgttctttga atacccaatt gaccatatta
    37021 aaatcaggat gattcaatgg atagacttcg attgtttttc ctttaacagt aaaagtcaga
    37081 tgatcgagaa attctctgaa tctttgagct gcctcgattg aagccccaat caattgacca
    37141 tatccggtca cattcaatgg caatacacga tgtgctgtcc agactgcggc ggcggttgct
    37201 ccagcttttg atccttccaa aatataagct cctaacatat ctggagcctt tactgatttt
    37261 tcaaacacat atggcgcgaa ataagaaatg atatttctca tatttttatg tttgattacg
    37321 attcctccag cagcataagg gacatagccc atcttatgag gatctatcgt gacagaatcc
    37381 gcttctgaaa tagctctgaa cccttcatat acctctttgt caatcgttac gcagtggtgg
    37441 aaaacatgat gttcttcaaa gaattcagct aaggaagcat acggcacaaa ttctcctgct
    37501 tcgtttagaa acagtgaacg cgcatagccg ccatatgcgg catcaacatg taaatagaaa
    37561 tagatccctt catcttttaa cctttctctt aattggacga ttttatctac actgtctact
    37621 tgaccttctt ctgtcgttcc tacgacagca accacaccta gaattgggat tttttgtcca
    37681 gctaattcac gaattgtttt ttccaaagca ttaatatcca ttcgataatc ctcttgaact
    37741 gggatagcaa ccatctgatc taagccgact ccgcaaatat ctaacgcctt catccaagaa
    37801 tagtgttttg tttgagggac cagccatttc cctaatcttt ggatattttt tccgctacgg
    37861 gaagaagctg ctttgacctc atccatttct tcgtccgtaa agctttcggt catttccaaa
    37921 atttcttcaa cagataaatt caaaagttcc cactcagaca tttttttcac tttttcaggc
    37981 agcacttcct tgacagctaa aggaatcgat ttgatgcaac gggcgtacca taatccttca
    38041 agattagcaa tagaaccatc tgctgcaatg tgtccccatc cgtctgtcat attgaataat
    38101 gaagcaaaat cctgtcctac ttctgcttcc atttgcgaag ttgccataga agattccaat
    38161 gcaacattat ttgggttcca cagcatcgca tagttgtaag ctaataaagc aggcatcaat
    38221 gtttcagcat tcatttgtcc ccagtaacgg cctgctgaat gccatgggat cgatcctgcg
    38281 cgtaatcgct gactgacttc atccaagacc tctatcatat ggtcgcgggt ggctagataa
    38341 tctggagtga gcttatctcc ttcgctaatt gcaggcatat ctgaaggaat ataattttct
    38401 ctccatccaa gatgttcatc taccatcttg ttcaacaaca ttttataaac tggtccattt
    38461 tcagctttgt cgcctataaa gacggccttg atatccatat ctttcatttt tcttccctcc
    38521 atattttgtt ggtcaatgtc ttgcagatac atgtgtttat ctgtaacacc tcttcactat
    38581 agcgccaaaa atgagaaatt tttttttata acatcaaatc cacgtagatt tttacaaaca
    38641 aaaataaata aagtcggatt tttctgataa ttcaacgcaa aaaagcgaac aatttttcaa
    38701 taaatcagtc ttctaaaata gataacctaa aaaaagcgaa caaacaaata aaatgactgt
    38761 ccttcattca ctaaacatat ttttattttt ttatattgtt aaaaattcac aatttatttt
    38821 ttaatagaat tatctgtttt ccaaatttta taacataaaa aacctttttt aacggcattt
    38881 atatgctttt tcagaaatta actgatgatt tcaaaaagaa aacatgtcat aatatttccc
    38941 atattgtgca aaaaaataca aggcggaggc tctactatga ttgaagaata tattgagaaa
    39001 aatattttaa gacagctgtt tttatgtggg caattctatg taaataaaga agtcaatcta
    39061 gaaaagctct ccaatctcct gcatgtttgc aaaaccactt tactcaatga tatcaataac
    39121 ataaaaaaag aatttgaaga acagatcgct tatacacatc gggaaaagga ccgttacact
    39181 ttatattttt cagaacatat acctcgatgc aagatcatgc agcaattgtc tcaaaattcg
    39241 ttgtttttaa aaacttgtct gctttatttg gaagaagatg aacctgatta tcttcaatta
    39301 actgaatgtg aattcatctc tgtcagcaaa gcttattcat taaaaaaaca agtattagct
    39361 tactttaatg actgcgggat cgaaatcgac cgctactccc ctcgattcac tgaaatggaa
    39421 agacgtctgc tgcttcttaa tgtgtcgtat cgtttaggcg gttttaattc ttgggagcta
    39481 cctgaatcgt tttttgaacg tgccgatcgt ttcattgaat ccgtaacgga aaatagtggc
    39541 agattttatg ataaagaaaa taaagaaatc ttatcgattg gttttgctat cagtttccta
    39601 cgccagcaag tgtgtgctgt gacaatagat tcaaaattta tcgaagaaat caaaaaacgt
    39661 cctatttaca attatgtcga atcagcatgg gaaaacactg atttccaaac ctattataaa
    39721 aaagaagaat tcgcctttat tttgacacta ttcaatcttt gtaattatgg tttccattct
    39781 tatcagttga ttgcggaaga ctttcaacag ctacaccaag tgtttattga caatactccc
    39841 gaaataaaag aactagttgc tacctttgaa tctcacttca atcaagaatt attcggaaac
    39901 caaccgttcg aacgtgcgct gattcatctg atgcgttcgg cttgggataa ctatcaatta
    39961 ttcatgccag aaaaatttta tcttttaaat gaggaacaga caaatttata taaagaagtc
    40021 cagacaattt tttccagctg gtccagccag ttaccttatg atctacggtt gaatcctaat
    40081 tgcatgcggg cttttgtgat cgaattgagc ggaattctcc gtctgacaaa agaacatctg
    40141 actatctata tcgtcacaaa ttcggatgtt cattatctga tttatcggga agccttggaa
    40201 gctgtaacta ctttcgattt tcaagttgca ccaacaattt attcaagtat atctgatata
    40261 aagaagtatg cgcagcagtc ctcaaaccgg gtattatgtg aacgtacatt atatacacca
    40321 gatgcggtcc aatatgaaaa tattattcct atttcgatca atacgatcga tcgagctatc
    40381 atttcagctg tgcaaaacaa ataaggggct gtgacaaaaa tcatgtcaca gcctcttatt
    40441 tgttgaagat gcccatttct gtaacaatct cttgatacac gtcaggctca caacctcact
    40501 tattttggac atctaggggt ccgatctctt tatttaaaaa ataagaaatg atggttcgga
    40561 taactaccaa cgccgctagt tggaaaatat cctgcaaggt aggtttgata atcgattcga
    40621 tgatcccagc tgaaacaaga atttccaaac ttagaagtat atagcctccc aacatctttt
    40681 taatagcatt gttctcgctt actcggtcgc tttgcacttt tgtatggaca aataaatatt
    40741 tcaaaaaatc cttgattgat agacaaacac cccaaaccaa taaacagata gcaaagatat
    40801 caagtcccag tacaagtttt tcgaaatatg gaagaagaaa ctgcatcaac tctgtcgtca
    40861 tcctacctct cctcttcttt gtttttcttt gtcttctatt tcctgattca agaaataaga
    40921 aatgactgtt cgaatgataa taataagtgc aagcttcaaa atatctgtcc aagtcggctt
    40981 gataactgac tcgatgatat cagcaacgac tagtacttcc aagcttaaca aaatataact
    41041 tgctagcagt tttcttgtat ctgcattacg agtattacgt tctgcatagt ttttcttgac
    41101 atgagaccaa tcaaaaagtt tgaatagaac aagaacgatc ccgacaatta agataccgat
    41161 agaacaaata tttaaaatag caatgatcca ttctagaaat tcaattaaat ttgagcgaaa
    41221 catatacgct acctactttc ttttaatttg ttcctattct tttattgtaa aagaaagtta
    41281 ccttgttcgt ctatttaaaa gttgttctaa tgataacggt tcgcttaaat ttttcttttt
    41341 cactctccca tttttctccc tccatccata aatcgtggaa gtatccaaaa caacgtagca
    41401 agttaaaata aggcttagtc cgtcatcagc ttttcaaaga agcactgtct cggtgctttt
    41461 tttgtaccca aatttctaaa aatagaacca tacacctcct caaatctttt cttcttacct
    41521 accctatttt tatttacagg aaaatcagac acttcttctt ttttgtcaaa atttcctttt
    41581 tcttctcgtc ctatcatttg gcattctaat aaaaacgaac tatccttgga tatagaaaga
    41641 gaaaacaagg aggcgttttt catgagtaaa aaattaatca aagtcggcat cggtttaggt
    41701 ttgcttgccc ttggcgctgc atatctagga aaaaagacag gactattcga agatgacagt
    41761 catttatatg atgaattcga atcaatctag catcctattt agttgaatca ctacggacat
    41821 acttggaaga cattggagga atcacaatga gaaaaagtaa agcaataatg attggtgccg
    41881 gtattgccaa tatggcagcg gctgtttatt tgattcaaga aggcaaatgg aaaggggatc
    41941 agatcacctt ttattcattg gatgatcacg gttcaaatga tggtgcaccg accgacactg
    42001 tagtggatga atattggaat aaaaaccatc cattagaaaa ccaaaaaggc tatattgctc
    42061 gaggcggtcg catgcttaat taccgtacct atgtagattt gatggatctg ttaagtcgaa
    42121 taccttctgt tactgagcca gggatgactg ctgaagaaga tacgagagat tttgatgcaa
    42181 aacaccgaac ctttgacaaa gcacgtttga tggaaggtgg caaaggaatc attgatggcg
    42241 gaaaactggg attcaataat aaagaccgta ttcttctgac taaactgatt gctatgcctg
    42301 attcagaaga agaaaaacta gacaatatca ctatcgaaga atatttcaaa gatgatccac
    42361 acttttttga aacaaacttc tggtttatgt gggaaacaac atttgctttc agaacacgta
    42421 gttctgctca agaattgcgt cgctatatgc atcaaatgat ttatgaattc actcaaatcg
    42481 aacatctagt gggcgtcaat cgaacacgtt acaatcaata cgaaagtatt atgcttcctt
    42541 tgatcgagta cttgaaagaa caaggatgca aaatcatttt gaaccgccgt gtcactgact
    42601 gggaattcaa agaaacaccg atgcaagatg aaatcactgt gactggtttg aaaattacca
    42661 atacactgac tcaagaagaa gaatacgttg tggtcgatga agatacagca gttattttca
    42721 ctaatgggtc cattacagat tcagctactt taggagatta cgaaacacca gctgtagaaa
    42781 atatggatta tggtgcagct tctagtctct ggaaaaaagc cagtgaacgt ttctacaact
    42841 tgggaaatcc tgacaaattc tttgctgatc gagatgcaag cgaatgggtc agctttaccc
    42901 tgacgacgaa aaaccatttg ttgttgaatg aaatcacccg tatcacgact caagaaccag
    42961 gaaatgcctt gaattcattt atttcaacca caccgatcac gccgttaggc caaaaagatg
    43021 tcaatatgtc tattgtcgtg catcatcaac cgcattttac gtctcagaaa ccaaatgaaa
    43081 cagttatttg gggttatttc ctttatccaa gacgacgtgg cgaatttgtg gataaacagt
    43141 atattaaaat gaatggaaaa gaaatgctag aagaactgat tggacaactt tcaaaagtag
    43201 atcctggacc agtgaatatt cgtgaaaaag aaacagaaat tttcgacagc gtaataaata
    43261 atatccctgt ctatatgcct tatgcttccg cgttgttcaa taatcgtgcc aaaagcgatc
    43321 gaccaaaagt cattcctaaa cattcgacca atctggcctt tacaggagaa tttgtcgagc
    43381 agccttatca gatgatcttt actgaacaaa gtgctgtacg ttctggagaa atcgctgctt
    43441 tccattttgc gggtattcct atgtcccgtc ttgtcaaaac accgcgttac gacaaagata
    43501 ttcctactct agctcgtgcc gcaaaaaaaa tgtttgaata atcaagaggt tgtgaaaaag
    43561 ctgccctgca tcaagtaata agaacaacca ggctaaaaca gcttcttatg tttttgattt
    43621 ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaccaaga ggttatgaaa
    43681 aagctgccct gcatcaagta ataagagcag ccaagctaaa acagcttctt atgtttttga
    43741 cttggttaga cttattaccg cagatgcaag cttttgaaca ccgtttacca agaggttatg
    43801 aaaaaggcgt ttagtttcga gtatgaagaa aaattttgtg aaaatggttc ctcacgtttt
    43861 tgcataaatt tgacttaata ccgagaaact gatcccttct gtcataacct ctttttattt
    43921 atgtctgttt ctttttgaaa acaactattt tttcaacgtt tactctcttg ccaatccaac
    43981 atcatctaac ggatacaact atttcaatga ttaccattac actaaaaaat cggaaacaca
    44041 cctctccgaa cacaaataca taagactata gaatgtttca tttaagaaaa aaagcgtttc
    44101 attatcaaaa aggtaagatc tcctttaaaa tgaaattatc tgtagtacta ataatgcaga
    44161 caattttatg aatctgaaag gagcatctcc aatgaaagca gtcacttggc aaggaaaaca
    44221 gaaaatggaa atcagaaacg tagatgatcc aaaaatatta gaaccaacag atgcaatcat
    44281 ccgtatcaca gcaacagcca tttgcggctc cgatctgcat ctttaccatc atggtgaagc
    44341 agttttggaa aaagggtatg ttgtaggaca cgaaccaatg ggaatcgttg aagaagtggg
    44401 atctcaagtt caaacattga aaaaagggca acgtgtggtt atccctttta atattagttg
    44461 tggtcattgt catttctgcc tgaatcacat ggaaagccaa tgtgatgaat caaatccaga
    44521 tcagttatat ggcgggcttt tcggatttgg caagttgaac ggtaatcatt ggggtggtca
    44581 agcggaatat ctaagagttc cttatgcaga ctctacttca tttgttgtac cagataatga
    44641 tcttcctgat gaaaaagttt tatttctatc agatattttg cccacagctt attggagcgt
    44701 tgaaaacgca ggagtaaaaa aaggcgatac agttgtgatt ctaggttctg gtccagtcgg
    44761 tctattcgct caaaaattcg ctgttatggc tggagcagag cgcgtaatcg cagtagatcc
    44821 agtacagcac cgtctagata aagcggctaa ttacaatggg gttgaaactt atttcttaga
    44881 agacacggca caagctggaa cagaattgta tgaactggct aaaggtggcg cagatgtcat
    44941 tatcgattgt gtaggaatgg acggattaga gcctgtcaaa gaaaaagcga aaaatttagt
    45001 aagcttacaa agcggcacaa tctctccatt acagatggca tcgcaagctg tcaaaaaatt
    45061 tggaacagtc caagtaactg gtgtttatat gactccagct tcttcttacc cgctgcaaga
    45121 attttttatg cgggatatcg ctgtcaagca tggacaggca ccaattatcc atctaatgcc
    45181 aaaaatttac gcaatgattg cagaaggact attcgatcct acacaaatca ttactcattc
    45241 gctgccacta tcagaagcag cacaagcata tgagatcttt gacaaaaaag aagataaaaa
    45301 tataaaagtt gttttgaaac cttgaattca gtaaaaaata caggtgattt tctttatgcc
    45361 caaaatcaaa cgaaataccc atgagatcga aataggaaaa gaagaagata tcgaaatacg
    45421 aggacgtcgc ttccgcttct atttccaaaa tcgttacaca ttgatctcac tggctgtcga
    45481 tttattaacc gggattttct atatttttgg aagccttgct tccttaacta aaatccccga
    45541 tcgatatggc acctattttt atttggctgg tgctattttc ttgacgattc gtcctattct
    45601 cagaatcgta aggaacattt ttatttacga cgaaaaaaaa gcaatgaaga gaacaagcaa
    45661 aaaaaaagag gcatgagaat ttttcaaatc tcatgcctct tttttcaccc tatcgtatca
    45721 ctttgataca gacgagcggt cgtcccactt tcttccttga ccattgtcaa aaatgtccac
    45781 tcgtatcgtt cataaaacgt ggtatgatct gtaattaagt aaagtttttc gtacccaagt
    45841 tgatgcattt cttttctgat ttccgctaat atccgcttgg ctatcccctg cttacgcttt
    45901 tccggttcaa caaacagggc acaaagattt ggtgtcagat cagggcggtt atggaagtcg
    45961 ttttcaatga cgcccgctcc tccgacgatg gtttcttttt catctaagac cacataccat
    46021 tgaggaatac tttccttatt agcgattcca gtacgaatac tttcctcata cacaacagca
    46081 ggaactcccc attttgatga aaaccaattc gcgctttgtt ttactaattc tgggtgttct
    46141 cttaatttga tccagttata tgtaaccaat gtttaaacct ccgactaaaa taaaacgttt
    46201 acaaaaatta tacaagtctt tatgaaaatt agcaatgaca acaatagtga tgtaaaaaaa
    46261 aaaacggaaa acaatcactt gttctccgtt ttttgattaa tcaagcatct aaagcttctt
    46321 ttcttctttc ttggatcgta gctaccttga cgaacggtag atagatcaaa atagaaagaa
    46381 ccaaattgac agcggctagt acaccacctg caatactttt tgttgccaat acaccgccaa
    46441 taattggtgg agttacccat ggaggcataa cggtagctgc tggcactaaa cctgtagaag
    46501 tcgcaaagta agcaacacta actaagacca ttggtgtcaa aataaatgga atgaacatga
    46561 tcgggttcaa cacgataggt aacccaaaca tcgttggttc attaatattg aagacacctg
    46621 gcgcaatcga caagtttgtt acaaccatat atggtttgtt tttacgtcct actaaataaa
    46681 tagctaacag taaacctaaa gttgcacctg ttcctcctaa gttgacaaag ctgtcaaaga
    46741 aaggtttgtt cacgataaac ggtgcgctat gtccagctgc gattgcatta acgtttgctt
    46801 caatggctgg cgcattgatt gtttgcatca aaggatcgac catattcgct ccgtgtaaac
    46861 caaagaacca taagaatggt gtgataaatg caagcagtaa ggcagatgga taagagtttg
    46921 caagtcccat aaatggttct tggaccactg tatagaaaga acctacgata tcatcaacac
    46981 cgaatgcagc aaaaattgca gcaactaaag caaacgcaga gatagtgatc attgctggta
    47041 gtaatgaagc aaatgctttt gcaactgccg gtggcacacc atcaggcatt ttgatgatca
    47101 atttttcatt tccgcttaaa cgtacaaaga tttctgttga aataatccca acaataatag
    47161 caataaacaa accgtttgag ctcataccta atgctccgcc taaagcgaag aaagagccta
    47221 aagaaatcac acctgcggaa acaccgtctt ttcggtagcc gttagctaaa tgataagcaa
    47281 gcaagaaagc aatcaagaca gaaagaatgg caaatgtacc gttccaagca gcagccccga
    47341 atcctttcca tgattcacca ccaaaaattg agttcatcaa ttcttggaac ccgggaatcg
    47401 gtaagttatt gatcattact gctaatgctc ctaagatcat taacggcata ctcaccataa
    47461 atgagtcccg aatcgcaact aaatgccgtt gtgcaccaat ttttgatgct acaggtataa
    47521 aatgtttctc cataaatgca acaaatttat ccataaatct tccctctttt ctttactgta
    47581 gattacgcgt tcaatcgacg atacagatca atgatctctt ttgctaaatc tgtaaaagct
    47641 atagatgtca tcagatgatc ttgactgtgg accgtcaaaa gcgtgacttc aacgtgattt
    47701 ccttgtgctt cttgtgtcag catctctgtt tgagagtgat gtgcttggac taaagattcc
    47761 tctgcatctt tgattttttc atctgctaaa gtgaaatcac cttttttcgc agcagcaatc
    47821 gcttccattg catcgctttt tgcatttccg ccaaacatga tcagacccat gatggcttct
    47881 agattttttt gatcttccat ttattgtatc ctccgataat ttttattatt tgtttattag
    47941 tttttctgct tggtcgagta ctttttcacc attcatcatg ccatagtcag ccatattgat
    48001 tacatctaaa ggaatgcctt taggtgctag cttttcagca aattgatttt gcataaagcg
    48061 tacttgcggt cctaaaagta aaacgtctac atttttagat tctagttgat tatccgcatc
    48121 tgaagcagat acagcaaaga tgtctgcttc cattcctttt gcttctgctg ccttttgcat
    48181 ttttgtgact aggagacttg tactcattcc agctgaacat acaagcatga ttgttttctt
    48241 ttccatttta aacacgttcc tttctatact tacacttgta tataagcaag tagcgtgcca
    48301 actttaaaag cgctttaaaa agttgatatc atcacattta aggtctatac caagttgcat
    48361 acacactaaa aaagaaagcg cacactaaac acacaaatta atttttatta ccttttttct
    48421 tttaacgtgc acaaaaaaag ttgtgacaca aaacttgtca caactttttt caaataaacg
    48481 gtattcaaaa gcttgcatct gcggtaataa gtccaaccaa gttaaaaaca taagatgttg
    48541 tttttacttt gctattctta ttacttgatg caggacagct ttttcacaac ctctcaataa
    48601 acggtgttca atcagctgac cctgggtatt agctcaaaac gctggattca caacctcttt
    48661 tatttcaaat aaccagtaaa tacaatgaac atctacaaaa aacttctatt tatttataga
    48721 tttcgtcagg caaatccaat tctctcttat caatcaaagt ctgataccac gaagcagatt
    48781 ttttcaatgt tctgcttcgt tcatcgttca attcgattcg aactaatcca tatcgattct
    48841 taaatgcatt cattggtgac acacagtcag tgaatgccca taacatatag ccttcgcaat
    48901 ttgcgccttc ttctgttgct ttgatcaagt aatgcaaatg ctgtccgata aattcgatac
    48961 ggtaatcatc ttgcacgatt cctttctcat ccatatactg ttcttcatat tctcttccca
    49021 taccgttttc tgttatcagc caagggatat tatgataatt ttcttttaga tacatggcta
    49081 tatcatacat gattttcgga tagatttccc atcccctgga attattcatt ttcttcccag
    49141 gtaaatcaaa gacttcataa tatcgttcag gatggaaagg tgtctcttca ttccattgat
    49201 aacgaggggc gcgaacgcgt ttaggataat attgattgat tccaaggaaa tctactgtat
    49261 gatgctgaat cgtttctaaa tcctctgttg caggatcgaa ataaatcgat tgtttttgac
    49321 acaactccag gaactcttct gtgtagtatc cttttaccat cggatcaaaa aatactcgat
    49381 tataaaacaa atcatacata taagcagctt tttggtcttc tggagaattg gatcgagcat
    49441 agaccatttc aggatttaaa atacagccaa tccttccacc ataatttccg ctgcggtaaa
    49501 tctctactgc tttagccgtt gctaaaactt tatgataatt ccacatcatc cacttttttg
    49561 tgttttgttc atgcggccag cgaacagcat ccaaatagca acgcgtttgg ggaacgattg
    49621 gttcgttgaa tgtaaaccag ttttttaccc tatcaccgta acgatcaaag gcaatttgag
    49681 catacttagc ataaaaatca actacttttc ttgaagacca gccatcatat ttttccaaaa
    49741 gaaaagctgg gacttcataa tgttccaaac aaatcatcgg ttctacgtct gcttcgatca
    49801 aagagtcgat catttcactt atatgctgag catattcttc atctactata cagttctcat
    49861 aatcagtaaa aaaacgagcc caattgatag aagtccgata atgtgtcaga tggatggatt
    49921 tcatcagatc cacatcctgc tggtattgtt ccataaaatt agttgctacg gctgggccat
    49981 acccattatg ccaaacaaaa tgttcatttt tataccagct atctataaac gaatcctgtc
    50041 cttctttttt tcctttccaa ccttccgttt gccaagcaga agatgcagca ccaagaataa
    50101 aattttttgg aatagtaatt ttcatgattt cctcctgttt tttagatccc atcattttcc
    50161 acacgatttg ctacttttac aaatggcaga tagatcaaaa tagaaacaat aatacaaaca
    50221 agttgcgtaa taactgcacc gatatttcct gctgttgcca gataagcatt gacgatcggc
    50281 ggcattggcc aagggaccat tacaactgct ttcgccgcaa atcctaaagc ggttgcaaaa
    50341 taaccaatcg ttccagtgat aagaggcgtt aagataaacg gaatagctaa aattggattc
    50401 agcatgatcg gcataccaaa aataactggt tcattgatgt tgaagatccc aggagcaagg
    50461 gataacttgg tgatttgttt catatcttcc cgttttccaa ctaacaatac tgcaatcagt
    50521 aaaccgatcg tgactccaga cccgcccata ctcatataca tatcccaaaa tggcatagta
    50581 ataatgttcg gtacttcttt tccagcttca aaagcttccg tatttacagc aattgccgct
    50641 aaaagcaacg gttcccgtat cggcttcacc atttgatttc catggatacc aatcacccaa
    50701 aagacttgcg caataaacat caatagcaaa atacccggta acccttgtac gacaccttct
    50761 aatgggcgtt gtacgacatt gtaaatgata tcataaaggt acattcctgt aagttctttg
    50821 atgataaatc ccgcagccgc gatacccgat acagtcagaa tcgtcgggaa taaagcagaa
    50881 aaactagcag aaacattcgt tggcacggta tcaggcattc tcagctgtag tttcttctgt
    50941 ttcctcaacc agcaataaag ttcaatagaa aggatggaga ccaacattcc caaaaataac
    51001 cctttcgtat ctgtatattg tttagccaat acgttttcta ctataacagt ctgattttca
    51061 ttcactaatt cataaacagt tggattaaca gataaataag acatcactgc gatgatacca
    51121 gggaatacac catccacttt attcagcttg gctaattcga tccctatcag aaaaacagca
    51181 tagatggtca agaaacttag tgtgacatag ctgatggcag atgcgatagg ctttaattct
    51241 tctaaaaaac gcaagaaact tatctgtgct aagccatttt ccgagtcaaa gaccattgct
    51301 gaaaacaatg tgccaaaagc acccgtaata attaccggaa tcaatgcagc aaatgcgttt
    51361 tttatcacca tgatatacct taaattattg attctcgttg ccacgttccc taaaacattg
    51421 gctaatttat ccataaaact cattccagat cccctcattc ctgcttcttc tccttgacgt
    51481 catctctttt tgtctattag tcagcgctta catttcgatg aacagaaact atttactcct
    51541 cttttttacc aaatataaaa caaaaattca tctgatgtat ttatcataaa atacatcaga
    51601 tgaactgtca attagtttct ttttctccta ttattttctg taattctctc cgatttattg
    51661 ccatatggac agtcattgca tcaaacgcag caagtgcatt ccgcctttcg atggcctgaa
    51721 cgatctctgt atgaatatcg atcgtctcga ttttcagatg ctggatatca taatttttat
    51781 taaacaaagc aattgattca ttaatgattg ggataatatg cagcaaggct acgtttccgc
    51841 tagcttctgc aatcatcgta tgaaaatcga tgtctaattg aacatgttct tgtgtgcctt
    51901 ctcgaaaaga agtttcaatc ttttgcgtta attttttcat ttggacgatt tgattcttcg
    51961 ttgcatattc cgctgccaaa cctgccatct taggctccaa taaatatctc agttcaaata
    52021 agtctcgtat catccgatcc tgatcttcaa tcaaagaaaa accgagtggg tcattggcaa
    52081 tccctcgctt atcactgaca aatgtccccg ctccttgccg aacttcaagg atattcctgg
    52141 aagctagagc ccgcacagct tctcgcaccg tgcttcgccc cacctctaaa taatcggaca
    52201 attcatattc attcggcagt ttatctccta cttgcaactg catttccttt aaatatctaa
    52261 ggatcttgtc agtagttact tctactaggg ttttattttc ttccaaacca catacctcct
    52321 tttcatctga tgtatttttt cgtaattatt ataacacgtt tgaatcatct gatgattttt
    52381 tgtatacaaa attgattaat ccgttcatag acatacaaac gaagaagata tttaccataa
    52441 aaaagactag gataaaattc actcctagcc ttcgatcatt tttattttga acgacaaaaa
    52501 atatgatgtt caataacaga cgatcttcat tcgattcttg atgtcatctt ttgttttttt
    52561 taatatatgg ataaaaagtt tgattacatc gtttctattc tagaatttgg tcgattctca
    52621 attcttcttc tggtgagaaa tctaaattat ccatcattcg aacactttct tgtaactgac
    52681 ttaaccgact tgctccgacc agtacacttg taacagattt ttgtcgcaaa ttccatgcaa
    52741 gggccatttg cgctaatgat tgtcctcgtg atacggcgat tgtttgcagt gctttgattt
    52801 tttccagagt tgatccaact tgttcttctg aaaggaatgg tatttcctta cgatgtgctc
    52861 tagaatcttc aggaatacca tgtagataac gatttgtcag caacccttga gcaagcggac
    52921 tgaacgtgat tgcccctagc ccttcttctt ctaatactgg agatagatcg tcttctagta
    52981 gtgcacgaga aaacatattg tagcgcatct gatgaataat gaacggtgct tcctttcttt
    53041 ttaaaatttc agtcattttt tttgtatctt ctccattata gttggatata ccaatatata
    53101 atgcttttcc ttgtcttaca agttgcatca aagcttctgc tgtttcttcc aaaggtgtat
    53161 cagggtctgg gcgatgatga tagaagatgt caacataatc tagccccatt ctttggagac
    53221 tttggtcaca acttgaaatg atggatttac gagagcccca ttccccatat ggcccttccc
    53281 acatatgata acctgctttg ctagaaataa tcagttcatc acggtaggct tgaaaatctt
    53341 ctctaaaaat acgcccaaag tttttctctg cagctccagc agggcctcca taattattcg
    53401 caaggtcgaa atgggtaatt cccatgtcga atgcgcctct taaaatctct ctttgattat
    53461 ggataggatc ataatcacca aaattttgcc ataatccgag agataaaatc ggtaatttca
    53521 aacctgaatg accggattta cgatattcca ttttttcata acgtgcacta tctgcaatat
    53581 acaatttttc tcctcctcat caaatctttt taaaacgctt tcttttttct atttttagtt
    53641 tactacattt taaagaaaag gagttaatca aaatgatttt ttcgtatatt tttttgccat
    53701 ttgtttttta ctcgttgata gatcagaaat tgattacgtg cttgctggat ttttttataa
    53761 cgtttcggtt gttttttgta aaattgctga tgatagtttt ctgctggcca aaacgtaccg
    53821 gctggttcga tttttgtgac gattggttgg tggaaagttc ctgaactgtc tagtttctgt
    53881 tttgattgtt ccgctaattc tttttgtcgt tcgacttgat aaaaaatcac tggacgatat
    53941 tgcttccctc tatcttgaaa ttgtccaaat gtatctgtgg gatcagtaat ttgccaatag
    54001 attgtcagca actcgctata acttatttct cttgtgtcat aaatgatctc cacagcttcc
    54061 acatgacctg tgtaaccacc acttacttga tcataatttg gtttttcaac atgtccgccc
    54121 gtgtatcctg acaaaacaga taggatccct tttttcgatt caaacggctc gaccatacac
    54181 cagaaacatc cccctgcaaa tactgcacgt tcttgatagt cagcatcttg catggcatgc
    54241 ttggaaaagt catatttttg ctccttatca aatccttccg taatcaataa ataaaagtcc
    54301 attacatcag gcgtcagatt cattcggata gctaatggac gtagtgttgc ttctagtttt
    54361 gataactgtt ctttaacgga tatattttct cttatgtcat tctttgtctg aatcaatact
    54421 tttcgttccc aatctcgtgt attcggattc aaaatcagat tataaagtgt ttgaatgaat
    54481 atttgttcct catccataga ttctcctcct ttccgaagaa gacaagctag tgactttagc
    54541 tgtaatttat cataaagtga ggaaataagc gattacttca tccccctaca gatttttcgt
    54601 ataaaaaaga gagaatcctt atcgacagat tctccttttt aatcaattta ttttataaat
    54661 gaaaagttaa tttacctttt atggaaaact attttaaaaa ataaacataa atatgcagtt
    54721 aatgtaacaa gataagaaat aatagtcgtt actgtataac ttgtgcttac tttaatatca
    54781 gcaactcctt tgactccgct tatttgtacc aatccattag cattcacctg ctcctttaca
    54841 ggttgatgat ttatttctac attcgttcct aaataagcat atacaggaag tgtgattact
    54901 tggctcttct cattagttac tctatatatg atagaactac cagttgtttt ataaggaagg
    54961 tttacccatt gactgccaat ctttgcttcg tgttttatta tatgctcctt attctccaat
    55021 gaagcgatag gagaataatc atataaaaaa taatccattc ctttagtggt atacgcctct
    55081 actgtttctt tgtttacaac aatatgtccc ggctgagaaa ttattttttg attgaaattt
    55141 tttttactag aaacaattaa agtgattaat aacaaaacag tcataaataa ataaaatagt
    55201 tctcttgtct tattgtatct tctatttttg aaaaatatca tcgttaatat cagagaagag
    55261 aatattattt gcaagcttaa gatccgccaa ggaaattgta acaatttggc tggcgtattt
    55321 tgcagaagat accatggcac caaactagtt gtagctagcc aagtcaaaca cgtaccataa
    55381 taaatctttt tttctatgtt tgttaatttt ttaaataaaa tcaggggaat acataaagat
    55441 aacagaccaa ctagtcccat tgagtaagta gttaagtcgt tgttcatagc ttcagtcaga
    55501 ctatcgaaca cattagatgc atgagcatat aaatttgtca cgctaggttt gttgattttt
    55561 tggtagagca tttgttcaaa catcggatac caaaaagcac tcgtcagaac caatgtcatt
    55621 cctgccgcac taaataattt tttaaatata gcaataaaat ctgcattctt gaaaccttta
    55681 gaaaccaaac gaataaaaat aaaaatgata attaatgctg tactcattaa tgttgatagt
    55741 acatggctgt acactagcaa actcatactc aatgctagct ttacagacgg atacttttct
    55801 tcttttccag agatgatttg ataagcataa aataatacag ggataacaag tgttattgcg
    55861 atagcttcgg caattgcgga acgatagtag atgtctactg tccgataagc agagaaaata
    55921 tagagacaac taaataaaaa tgccgctttt ttttgtttta aaaaccgctc gccataatga
    55981 taagctacga gtgttgtaca caagttcaat aaccaaacgt aaataatata gcttacaatc
    56041 aaattttttg tcatccaata taacattaca gctggaaaaa aagtcagaaa gggataaaaa
    56101 taatttacac catatccagt ataattgaat gtctcataat taatcggact ggtaaaaata
    56161 gtcgataacc ccttgattcg agataagtga aaagaaagat ctccagtggt ataaatactc
    56221 tgtgtatttt tgaaaaagat gaaagaatat atactactaa ctataattaa tccactcaat
    56281 attactactt ttttatttat tttcattctt cttgtttatc tcctttttag tcacatatcg
    56341 agaatctttc aacttattag gtgcaaatcg tttaaaactt gaatacacca ctaaacaata
    56401 agtcagaata ctgatccata aagccatgag agcagttgga gtatattttg ttgtaatttc
    56461 tatcttattt tctccagcat ttacatccac attcactaag ccatgttttt tataagagtc
    56521 atttacgact ttaccgttta cttttacctg tgtacctaaa taagcatata ctggtactgt
    56581 cactttttgc tttttgttgc ttgccactgt gtaagtaatg ttattatctg cagctttata
    56641 cttccctttt tcccacgatt ctcctacttt tacttcatgt ttttctaagt gaggcctttc
    56701 ttttatcgct tctgttgggg cgtaatcgta taatcctccc atatctgatg ttgtataacg
    56761 tgggagtgtt tcttcattga taacaatatg accgtgtttt gattggataa cttttgcgta
    56821 attttctttt gctgctatag acgtgacgag tagaaacacc acagtagcgc caatgattaa
    56881 ccatgaatat tttttattca tagtcttttt cataaaaaca agcgttatga tcattgaaga
    56941 aaaaaagatt tggataccta agatacgcca aggaaactgg agtaagctta tcggtgtttt
    57001 ttgaaacaaa aaccatggaa ataaattagt tacgcatacc catgtagaaa ctacgccaac
    57061 atagatgatt ttttcttttt tctccatttc tttcagtatg aataaaggaa aaatcaacgc
    57121 aaccaatcct aataacccca tagtgtatgt tgtaatatcg ttatttaacg cttgaatgat
    57181 actatctgaa atagaaagtg cttctagctg caaatctgtt ttgaagggac tgtgtatttc
    57241 ttgataattc atctgctgca acataggata ccaaaaatag ctagttaatg cacaagtcaa
    57301 aaaaacagcc tttactaaat tcacgaccac aaattttata tcgtttttta tttgcttgct
    57361 taaaaacaaa cgaactataa tcatacaagc aatcaatgca ctacacaata gtgtagttaa
    57421 gacatgagta tacacaagta gacttatact gacagataaa gcgatgactt ttttttctct
    57481 attgaatatc aatccataag cataatataa aacagctggg ataatcgtaa gagcgattgc
    57541 ttctgcaatt gcggatcgat aatagatatc aactgttcga taagttgcaa aagtatataa
    57601 acaactaaat aaaaaagcag catctatctt tttaaaaaac ttttctccat aataaaaact
    57661 aatcagaatc gtacaaatat ttaataacca aatatataga acataactta atattaagtt
    57721 atttgaaatt ccataaaaaa cgactgcagg aattattgta agaaaaggat aaaaatagtt
    57781 cagtccatct ccataattgt taaatgttgt atagttgatt ggcccttcaa aaatagaaga
    57841 taaccctttg attcgtgaaa gatgaaaaga taaatcacct gttgtataaa tttcttgagc
    57901 atttctcata aaatttactg aatataaagt actaagtaag ataagaacta ctaaaagaaa
    57961 tgctttttta cttattttca tagatttgtt gttctccttt tttaattcta ttttcagtat
    58021 actagaattg tcttttttta ataagttttg cgttaaattt ttcatagcac tagtatgata
    58081 tactagaaaa gaatcaattt ttattacttt taaataggag aaaaaaatga aaaaaaacaa
    58141 aaaccaaata atagatatca tttttatgtt atttctaagt tttgcttacg tcatccctct
    58201 attcatgtct aagggaatct atcatagtgt caatcaggat acttactttc atttatctcg
    58261 aatcatagga ctagataatg tatggagttc tccagtaaac ttcaataact tcgatcatca
    58321 tggaacaatg atgaatattt tttatccatg gcttactctt tatccagctt ttttatttta
    58381 taaaatgatg ggaaatcttg ttttaagtta taatatctac tattttttta tcactttttt
    58441 aacaatggtc gtttcttatt tttctatgaa acaaataaaa aacaatcgtt atatttcgct
    58501 gttattttcg attatttata cattttccgc ctatcgtgcc attgacatat tccatcgtgc
    58561 ttcattggga gaagctgtcg ctttaacatt tttgcctttg atactaatgg ggtgttacga
    58621 aatttatatt agagattacc aaaaatggta ctggttgtct attggcatga cgctagtagt
    58681 gtatactcat ttactttctg tcgctatggt ttctgtattt attggaggaa cgttgtttct
    58741 ttctttttat ttttgggacc aaaaaatcgc tagactctta agtcttttaa aagctaccgt
    58801 cctcaccttt tttttaagtg cgggattctt aattcctttt attcaacaat ctagagcaca
    58861 agaattgaaa gtcccactgg gaaaagaatt aagtggtatg gctcctagtg atatgctgac
    58921 acatatttta aataataact ataacaacta tactattgga ttattcttat ttctcggatt
    58981 gattggtgct tttattttta taaaaaaatt aactgctgat gatttattta ttttctttct
    59041 tggtgtattt gttctttttt gttcaaccaa tttatttcct tggcaacttt ttaaccatac
    59101 accagttaag agtctacaat ttgtctggcg gttaaatggt ttttcttctt tatttatagc
    59161 ctatacgatg agtatagtga tctattatat tttttctact aaaaataatt catggaaaat
    59221 aatggtcttt acgtttcttg cactaatatt gcatctctca ggagtaagca attctatcca
    59281 tgctaacaaa gattcattaa cacttatagc acctgaagac gctgttgcta tagctgaaaa
    59341 ttacaatcat actgattatg caaacaaaga gtcaatctat catcctgata tgattaataa
    59401 tgatcaatat ttactaggta accaggaaat aaatccaaca actcatttta tgagtaacaa
    59461 acttacaatt gaattagata attcgaataa taaaaatact gtcttgacga cacctattta
    59521 tcgttataaa gggcaagtgg cttctattaa tggcaaacta gtacaaacaa aattatctaa
    59581 gtttggcaca actgaattaa ctattcctcc aggtataaat aaagtcgtta ttacttatca
    59641 gtacacaaaa ctagcaattg cttcaagata tttatctatc gttactttga ttttattttt
    59701 actttatcga tttacttttt ctaaacaaaa acaaccgaga agagaagtac aacattctca
    59761 ctagattttt atttaagaaa gactttttag ctgtacacat aaacaggcta aaaagtcttt
    59821 ttttatattt ctttaatttg cttcatacat tatttaacat cgatatttat actgtgaaac
    59881 atgcgtttca tccattatca aagtattttt atcgataata aacttcatcc aaaaacagac
    59941 cttgtgcagg gacggtttct cctgcatgtt gccgcacttt gctttcaaat atttcatcga
    60001 ttgtttctat cggcatggca cctgtgccga tttctagtaa tgtccccatg ataatccgca
    60061 ccattttata taagaatccg tctccgacaa aagtaaaatg aagcatttct ccctttcgtt
    60121 cgatagataa ttcatcaatc gtacgcactg tggatttttt tgattttttc aatgcagaaa
    60181 aaccaatgaa atcatgtgta cccactaatt tttcgcaagc tgcattcagc ttgtccatat
    60241 ccaactcttg agggaaataa aagctgtggt ttcgctcaaa tgctgaagga atcacgttgt
    60301 tccaaacata atagctgtat tttttgccca ccgcattata tcttgaatgg aagcgctcag
    60361 gcatttcttc gattcttttg atgacaatat cccgcggaag gtaacgattc ataaagtcga
    60421 tcatttctgc cagtccaatt tctgtgtttg ttttaaaatt tgctacttgt cctcgcgcat
    60481 gggtgccagc atctgttctt cctgatccaa taatttctat ctcttcattt gtcatctgat
    60541 gcaatacttt ttcgattttt ccttgaatgg ttttatcgtc atctccaagt ctttgccatc
    60601 ctgaatatct ttttccgtca tattcgattg tcaacttgat gtttctcata ttttagtggc
    60661 tcctctgtct tccatttggt cttctctcta cctttttaag attgtagcac aaaatatagc
    60721 tccttgcttc tctaagacag aagctataca agaaaactgt ggaaatatat atttcagaaa
    60781 aacaaaaaac agccaccgga tgaagtatcc gctgactgtt caatttgacg gctcaagttt
    60841 tactgtttga gatgcaagat actcaaccag gcaatgggca cataattaaa gaaaaaactg
    60901 attctttggc aaaaacctat tttattcagt aatggccaag aatttataga aggaattctt
    60961 gccagtccat aaatcgccgc aaaaagcaaa ctgatcacag acagtccaag gtataagtgg
    61021 cttacgtcca tttgcccatt ttttcgatag atcaagaaaa gaagaactgg aaacaataaa
    61081 aaaccactgt aacctaaacc tgatccgata ttatggaccc atgtcgagac attccacgaa
    61141 gattcatggg tattgatact gaacaaacct gtaaagatac aatcacctat accatagaac
    61201 gcgatggctg ctgtaactag ggtagctaac acacgagatg tactaacaaa tgcagcatac
    61261 aatgcaggca atgacaggat gaaaaagatc cctgaaacca cagaccaaat aagaaacgct
    61321 tttcttacag gactggaaac ctctccaaat acactgatca cgctcttcat ttgatctaat
    61381 tcaggataat acaatcctaa tacgtacgga gtcaaaaaat cactcagcac gcctaataat
    61441 aaaaagaaaa aaccaaattt acgtaaaaaa tccatgatac gcctccaata acaattacct
    61501 atgcttttaa ttgttattat aaacgacttt atcttgattt aacagaaacc tctatttaca
    61561 cgaacatcta tataactcat taaaaactcg aatcatttta aaaatactaa atatctaacg
    61621 ttcaacgttc acttaatcca tctaaacaat ctttcaattt gattttttcc ccacttcttt
    61681 tacgcgcgcc tagctctcct attgcagtaa acaacagatc acttgacgaa tttaaggcag
    61741 tttccattga atcctggata acaccgataa taaatccaat accgacgatt tgcatcgcga
    61801 catcattaga gataccaaac aaactacatg ctaatggaat caataacagt gaaccgcccg
    61861 caacacctga agctccacaa gcagctaaag cagacaaaat acataaaagg actttcaaaa
    61921 caaaaggtgc ttcaatccct aaagaatgta cagcagtcaa cgtcatcaag gaaatggtaa
    61981 tcgcggcacc gcccatattg atcgtagcac ctaacgggat cgatatggaa taagactctt
    62041 ttgtcaattt caatctttca gccaacatca tgtttatcgg gatatttgcg gcagaacttc
    62101 gggtaaagaa agcgggaagt gcgctttctt tcaaacaaaa gaaaatcaat ggatagggat
    62161 tttctttaat aaacaaaaac gtgaggaatg ggtacacaac taatgcgaca aacagcatcg
    62221 taccgatcaa aacaagtaaa agctgcagat actctgccaa tccagcgatt ccagtcgtag
    62281 caattgattg ataaaccaat cctaaaatcc ctatcggagc aaatgcaata atcacttgta
    62341 cgacttgtga caacgctata gatatctgat ccaccaactc ttttgtcgat tctgaacgtg
    62401 ctcgaaaagc tagtcccaac aatacagccc agaataagac gccaaggtaa ttcgcatcaa
    62461 taagagattg aacaggattt tgtgtgacat tcgtcaacat agtagataaa acactttcca
    62521 aactttgcgg tgctttttca gatactgttt cttgtaaagt aataggaaca gtaaaaattg
    62581 aacttacaat aactgctaca agtgcagaaa gcaatgttcc cactaaatat aagatcaaaa
    62641 taggcttcac gaatgtctta ttcccaattt tatgcttggc aattgacgcc atcgtcaaga
    62701 aaaaaaccag aataggtgcg attgccttca agcaactgac aaacaacgtt cccaatattg
    62761 aaataaatgt ccatgtgggg aaaaagatac caaacaatat tccgactaaa ataccaacaa
    62821 caatacgttg aactaacgac atatccaaaa acttctctaa caaatgacca ccctttcaca
    62881 attttaacaa tcattgtatc attttatgca aagaaactaa aggtataatt ttctaaaaat
    62941 tctaacaata caaacaacca tttcttgcta attttgtact ttttctgtct acacgttgtt
    63001 ttttgagata ttctaagtta ggatgttatt aatgggcaac ttatcaggaa acgttttctt
    63061 atgtttttgt ccaatttttt tgtgaggtgt ttattcttga aaaaaataaa gaaggagagt
    63121 tatggcttcc tgacaatctt tgtcgcttgt ataatgatgg ttttacagcg tatattgatt
    63181 tcagcagtca ctattcctac atatgcaaca aaccctggtc gattctacat ctatacattt
    63241 ttacaaactt ccgttgttat tggtgcaaat ttgatcccac tttacatggg ttaccaatat
    63301 caaaaaatcg cccgtttaaa agttttacat tatttaagtc gttttgcctt tatattccta
    63361 atagccacac tagtttgcaa tatctttttt tacgtacaag ctggcagctt gaatattcgt
    63421 gattattggc ttatcctaac acctatcagt cagaattact ttacttatgc tgtttcttgt
    63481 actttgcttt tttgtagtat tccttataca gttggatttt taaataaatt atcgaaaaca
    63541 acaattaaat atctactatt atttttaaca attggattag ttggctgctc tactctattt
    63601 aataaagacc cgtttgcatt acagaatgga cagagtattt tatggatttt ttatttattt
    63661 ttaatgggtt atggtttgaa agaatggaac tggaaagaaa aggtccgcta taagcttcct
    63721 caagtattta tcagcttgat tgttttattc ggtttgatta ttttgatgac acaaatttca
    63781 ctcatcatca gaggaaatac agatacagcg ctgaggtttt ctaaaccata ttctctcttc
    63841 gcaatgtatt atactttctc ttcgttttta tttttagaaa tgctatctga taaattaggt
    63901 ataaaaggaa gaggaaattt tcttgctgta tttttgattg tcactcaagt tatatgtaat
    63961 ttccctttag tttcttatcg cgtatctaca tttatgaaac gtgaatttcc aaactcaggg
    64021 aaggcatggc tgataaatat cgggcagttt tttatttgat atttattagc agtgtccctc
    64081 ctagttatct ttttatttta tatacaaaaa atccgtttca ttcatcgttt catcgaatac
    64141 ttcgcttttg attcgattga acaattaact cagcgttgga aaaaaagaat tcattggctt
    64201 tttgttcata aaagttattt tttagttgca gcattttttt actgctttac cttcgtgcag
    64261 attttcgttt tagaaccaaa agaaggttgg aaagaaacta tccaggttgc cttaaaaata
    64321 tttactcagc gacaagcacc catgatcctg acaatcatca ttattatggg atttttcttc
    64381 ttactattgt tgatttccaa tcgtttttgg tacgccttga ctgctacctt gatcattaac
    64441 ttactgctca ctatttcgac agtaatcaaa atggaaatgc gggaagagcc tgtctttcct
    64501 tcagatttaa aaatgctgac cggattgtca gaactattat cgatggttag cccagtctta
    64561 ttaatcgtgg gcggattgat ccttctccta ttattgatta ctagtattat tgtacaacgt
    64621 agactacaaa aacagtattc cttgaagatt cattggaaac gtcgatttat cagtatcgct
    64681 gtattattag gatgtttttc gggtgtcttt ttcattaatc acaaaaattc gccttctttc
    64741 ttgctgttta atttatttaa agtaaacaag actttcttta accagcaagg cgccgtaaaa
    64801 gataacggac cagtcattca attcctaaac aatatcgaca ttaaaatcat ggaagaacct
    64861 gctggctatt cgaaagaaaa aattaatgga ataatgaaaa agtacaacac aaaggcagat
    64921 gaaatcaacc aaacaagaag tgactggtta aacaatcaga cgatcgttct caatttaagt
    64981 gaaagcttca gtgatcctgc acgtgtccct aatctgacag tacctacaga ccctattcct
    65041 tacatcaaaa gcattataac agaaggaaca ggaggattga tgttatccgt cggttatggt
    65101 ggcggaacag ctaacatgga atgggaagga ctgacaggct tgagtatcag taacctgtct
    65161 gcttcgttag ttacacctta tacccagcta gtggagcgtc agaaaataag tccaaatatt
    65221 accgatctat tcgatgaaaa aatagccatc catcctttta cagctgctct ttatcgcaga
    65281 aaacaagtgt ttgataaatt tggttttgac aggttctatt atttagacag tccggataaa
    65341 ttaacttata cggataaaat agaacaaagc ccacgcatat cggatgattc agcatacaaa
    65401 gaaaccttga aagctttaca aagcaatacg gaaacgtcac aattcatcca attatccact
    65461 atgcaaaacc atatgcctta tgatgattac tatagtgaat tgaactacac tgctgaagga
    65521 actgctgtca ttcctaatag aagaaaagaa ttacaaactt atatgcaagg ccttcactat
    65581 accgatacag cagtaaaaaa attcatccaa gaaatcgaca aaatcgataa accgattacc
    65641 tttgtttttt atggtgacca tttacccgca atctatagtg ggaatgattc gaaaaaatat
    65701 ggattagaac agcaccagac agattatttc atttataaca acaagtatag tcgtgaacaa
    65761 gcagctacgt taaataaaga agttgttgct cctaataact ttggtgctat ggctcttgag
    65821 catgcgaata tcaaagtaac tccttactat gcgttgttga cagaagtatc taatcatcta
    65881 cctgcattaa caattgatcc tacagaaagc ttgtctaatc gttttaatgg aaaacaggtc
    65941 tttgttacag aggatagtca aattatccaa gaaaaaaatt taactgagaa acaaaaagaa
    66001 attctagaag attatcgtct gatacaatat gatcttgttg caggtaacca gtacagtgca
    66061 acatgggcga cacaaaaaat aaaagactaa caaataaact gagcaagggg ttgtgataaa
    66121 agacatgtca caaccccttg tttatctcat taatttgctt gtccataaac gatttgatta
    66181 aagccatttt tcaattcatt attcgctgtc tcgttgaagt aaagataatt atcgggattc
    66241 ccctgatttt gttgtgtcac caatactttt ggctgatttt gctgaaaccc gaatagatag
    66301 acgtgctttt tcagatatgg ttctgtctct gcatcggaat agacggctgt gatttgatag
    66361 tctgcttgac ctgtcccact ttctgaccat tctgcagaaa caggcactcc accaatagcc
    66421 atcttccact ccccgttcaa aatagcttga gggactttaa gaccatataa gtccacactc
    66481 atttgattcg tataactttt gtattgttgt cccattgttt ggccccattt ggtcataaat
    66541 gcctctaatt gtgcggattt gtctgcattc cacagtgttt gttcaacttg ttcgctgctt
    66601 tctgaagagg aagatgaagc ctctacagaa gaacttgaag tagatgtttg agttgtttca
    66661 gtcgttttgg aagactctga cgaagtagag gtatctgctg tttctgtact tgctgcagtt
    66721 gacttgctct ctgtgctagt tgttgtagta gttgcaactg ttgctttcgc tgtttctttt
    66781 gttgattctt ttttcgattc attcccgttg gtacaaccag ctaacaaaaa agctagacca
    66841 attgttacta aaatcctttt tttcaattaa aaaactcctt tcgattactc ccacttcttt
    66901 attctatcaa ataagcaatg tgattttatt gatttttcgt attttctcat caatctttca
    66961 aatcttctaa aaactgagaa gcacccgctg atgttgtctg taatacatca gcgggtgctt
    67021 cttttatttt aatcttcgtg attttccaat ttacctcacg ctttatattt gtatttgaag
    67081 aaacatagac ttttagtcat catcgtcttc ctcatccaaa tcttgtcgga cagtttttcc
    67141 ttggagtctt tgtacttggt agatgatttc tttattgaaa cttaaaagtt caacaagcaa
    67201 ttgttgcaag ccatattttt cttctttttc agctaatttg attgcccgtg tgataaagac
    67261 attttggaaa tcaaaatctt ttgcaaagtt ttccaacatt gttgaggctg gtaaatattt
    67321 gttttgacca tgttcgtaaa tttttccata acgcatgact tcttctaaag tagacggaac
    67381 gatttcattt tcaatcacta actcatgaga gattttattg aaccatctcg cttcttgatc
    67441 agcatattct gaaaaaaggg tacttaattc ttgcgaagat gtacccaaaa catacaattg
    67501 tgcttggatc aatttcattt cttctaattt aaaatttgct aatacatgcc ccaccatggc
    67561 gccagcagtt ggtttatgat ggtcgatatc tgcttgtttt gtttcttgaa caaatttttc
    67621 ttccactata ttcattgatt tacgcctctt ttacttttgc tgattggact tcataaccta
    67681 atttttccac aactgcagct aattgttcag ggtggacttc atctggatca aagtttgctt
    67741 tgattttgct cgcattaaac aaaactttcg tattgcttac cccaggctgt tgagaaaccg
    67801 catgttcgat tttttgcata cagcttggac aagctagtgt atctaattgc ataataattt
    67861 ttttcatcgt agttcttcct tcctttttct tgatagtctt attctagatt acagcttcca
    67921 taaaaaaatt gattcttatc aagttttacg atttttcttc tttgctttcg tgtccaaaat
    67981 acaataaacg catcgcgtta aagataacga tcaagatact agcttcgtga acgaacatcc
    68041 cactagccat gtaaataaac ccggcaaata agccgttgag taaaaataag acgacaccaa
    68101 tggcaatcac tacattttca cgggtattta aaacagtttt cttagccaag cggtaggcat
    68161 gaaccaacga ttcaaaatta gattgcatca agacaacgtc actcgtttcg atagcaacat
    68221 ccgttcctga tcccatagca atcccgatat cagccgcagc caaagaggga gaatcattga
    68281 ttccatctcc aataaaagca acgcgcaatc cttgttcttg gtattttttc acaaattgaa
    68341 ccttttcgtc tggtaataat tcagcatgga cttcatcaat gcctaacata tcagctacat
    68401 aatcagcagt catctgatta tcacctgtca gcatcactaa ctgttttgct cctgcttgtt
    68461 tcaacttagc taattgttca gcgacttctg gtcgaatcac atctgacaca cctatgattt
    68521 gagtgatttt tttgtcgatt gctacaataa tgaccgagct gcctgtttgt tgtaattgat
    68581 gtaaatcttg tacttgcttt ggtgtgagag aaagtttgtg agcggcaatc aatttggtgt
    68641 tgcccgcaca aactgtatga ccatcaatct cagctgtgat tccttgtccc ttgattgtct
    68701 gattatcttt gactgctaat tgttgaaaat caatgtcttt ctcctgagca taatggatca
    68761 cggcgcgccc cagaggatga tcggataacg tttctaatcg agccactaaa gctaagctgt
    68821 ccccttcatc ctctgtatag ttcttgatag tggatacagc agtagttcct ttggtcaatg
    68881 taccagtttt atcaaagaca aaagtatcga ttttggaaaa agtatccatt gcttcaccgc
    68941 ctttgactaa gatgccccgt ttcgctccat taccgattcc tgctacattc gaaacaggcg
    69001 caccaatgac taaagcgcca ggacaaccaa gaaccaaaac agtgattgct aaacgaaaat
    69061 cacgactaat cagaccaaca accaacgcaa taagtaaaac ggttggagta taatactgag
    69121 aaaatcgatc aatgaatttt tccgcatggg atttggtatc ttgtgcttct tctactaatt
    69181 cgataatttt ggcaaaggtc gtatcatctc cgaccttagt tgcttcaatc gtcacgtagc
    69241 catctgctaa aatcgttcca gagaagactt catctccact gattttgacg acttgtcgtg
    69301 attcaccagt cactgcggct tcatccgcat accctttccc gtcaatgact cgtccgtcca
    69361 caggaatagc tccaccagtt tttactaaga cgatatcgcc ttcttccacg tcatcgattt
    69421 ccacttcttc agtcgttcca tcttcttgga caacactagc agtagatggg gccatctcgg
    69481 tcaaagcctt gattgactcc cgcgttttgg tcaatgtttt ttgttccaga tagctaccaa
    69541 acaaaaacaa gaatgtaacg atagctgact ccttgtattc tccgatcata aaggcaccaa
    69601 gcacagcaat agtaacgagt aaatcaattg agataacttt gactttcact gcctgatacg
    69661 catggatcat aataggtatg accgcaataa tagaagctat ggctagagca atgttataga
    69721 acaagacaaa accagtaaat tttccgataa aaccaaaaat aatcaacaca gctgataagg
    69781 cggtgatatg atttcgatgc tcttggatcc acttttgtaa tttcatcttt ctccctcttt
    69841 tcctttcatt cttacgagac taagtataga tacttatcca tcataaaaaa ttgaccacta
    69901 tcaagtttag tcaaaaaggc ggttttcttt tggtagaata cactacaaaa aatagttagc
    69961 aagaagactc actaaaagtg atcttgccaa ctattgtcgt ttctatcgaa attttcattg
    70021 aatgattttc ctgtacagca tacatcggag atctatttct ttatctaaga tttttatctt
    70081 gctaattttt tcctttagtc tttcaaatcc acgtcgttca tagaattgat acgtacagcc
    70141 actatctgta aaaaggaata tttcttttcc tttctctctt ttttcaaatt ctgttagcaa
    70201 cttggtaccg atgccttttg ttttcaaatc aggatttgca gctaaaaaaa tgatctctcc
    70261 atctggcgaa tgcttcttta aatatgctgc aagcatttgt tcatttgctg tctcgtaagc
    70321 tcctttactt tctttagcaa atatattttg taaaaaatcg aatatcttaa catatatttg
    70381 ctgtccaaaa gaacgatgtt tctttttttc tccttttatc tccgccagca aaacacctgc
    70441 caactcgtcc tctgcataca aagcaagaat ttgagttgct cgattcaact ccatatacaa
    70501 aaaatatctt ccgtaaagat tcagcagaag ttcattttcc atatatctct caaagttcat
    70561 tccttcaaca gcaaaataga tagctttttt gtaatctttc ttttctaagg gtttaaaagt
    70621 tagtttcatc atttcgcctc ctcaacttca atgattgtgt tatacttaca ttataataga
    70681 cacagtgtct actatctata atcaatcatc tataagtttg tcgattaagc gacagctttg
    70741 ctttgatatg tcggataagg agataggtaa atgaaaaaga cagatagacg cgtcaaaaaa
    70801 acagaaaaag ctttggctga aacactatcc acattattag taaataaaaa gattcaagca
    70861 atcactatac gcgaactaac agaaacggca gatgtacatc gttcgacttt ttatacacat
    70921 tataaggata tctatgatct atatgatcaa ttagaaagca acttttttcg ggatctaaat
    70981 gaaattctct cttatgatcc agcccatagc tatgaggaac tatacactcg cttgattgac
    71041 tatgtttacg caaatacttt tttatatcgc ttatttatcc tcaaccatgg tgatatttcg
    71101 tttcagaaga aagttaaaca agttattgaa gaaaactatc tgaacatatg gctatatgaa
    71161 gacaagaaaa cgattatcac agaagaaatg agattcttta ctacgtacca cgtccaaggt
    71221 tgtctatccg ttctcaatcg gtgggtagaa agcaattaca agtactccaa aaaagaatta
    71281 ttagaactct tacagaaact gaatgatcac atagagaaaa tcatgccttg aataaaaaca
    71341 tactaagctt agttaagaag aaccgtaacc ttctcgtata acaactgaat cttatttagc
    71401 caaattgttt actgaagatt ttttgagtaa aatttctata attcctactt attgaaaagt
    71461 agtttgtagt gctgcttctc cctctctaag tgatatatct tgttgtacca atcaaattca
    71521 cctcatcatt aataaattac ttttaggcta atttattaca acttataggt tgaagctgta
    71581 accaatttat agtcatatta tatttttatc atccagttta ttgaattctt ctcgtttacc
    71641 tcaattcatt ttcaagggga atcagctcat catctaacat tttacgccat gctcgcttca
    71701 tttcttgtgg gtatttaaat ggtttcgctt ctggatgttt ggctttatat ccttcgtaat
    71761 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
    71821 gattagaagc atgtaatttt ttctcagaaa caaaccactc attggaaaag acatgaatca
    71881 aatcatcact tacttgtgta aaatagcgac gtttaatgac aaagatatct tcattgctat
    71941 ctagtgtacc ttcatttctt tgtgcttaaa ttcaaagata attttctcaa taaagatttt
    72001 tgattccagt aagattcctt tactcctttt acaacatagc gttgtccttt gttttgaaac
    72061 atcttcttcc cctctttgcc attaaaaata gcccaattct ctataaagaa gattaagctt
    72121 cattattata atataaagtt taaatttggt ttattactta ctttttctta ttctctagta
    72181 agctaatatt gaaaaaaatg taatcagatc attattttta tatgttgtaa cttcctgata
    72241 agaaaactaa ttaaaagaaa gaggtaacta cataaactaa ttaaaaaagc taacttcata
    72301 gttggaggat aaatggaaga aacttcaatg attgtttctc cttgtgttcc ttcaatcgac
    72361 actagtccta ttatcaatct ctcttttttg tccatttact tttgcgactg ttccccaata
    72421 atcaaataca ggaagcgtta ttttttgtcc tttagattca tgtactgtat agactatttt
    72481 cgaatccatc acttgataag gcatagtatg ccattccttg ccaattctta cttcatgatt
    72541 ctgcaaatgt tctttgtatt gtaatgcttc cgtgggtgca tagtcataaa gtcctccggg
    72601 aaggagtgtc gtgtaacgaa taagattttc ttgattcatt accaagtgat ctctctgagt
    72661 gacaacttta tgttcatagt ttgcttttgt tgcagcagat acagccaaca gtaataaaac
    72721 aattgccgtt atattaacta cttttctttg cttagctgat gtgctcttca tgaaaacgaa
    72781 cgataaaatc aacgagccaa acagtacttg aaagcctaag attcgccaag gaaattgaat
    72841 catttgaatg ggtgtatttt gtaataaaga ccatggaaaa aatttggtgg ataagagcca
    72901 agagactacc gcactaaggt aaatcacttt ttctttgcga ttaaatcctt taaaaaagaa
    72961 gagtggacag atcaaagaaa taataccaat gattcctacc gtaaaggttg tcaggtcatt
    73021 attcatcgca ccaatcaaac tatccgagac atttaatgct tggtgttgta aggtcgtttt
    73081 atctggctca ttaatcgatt gaaccatgat ttgtcggaac atcggatacc aaaagtatgc
    73141 tgttaaaaga atcgtcattc ctactgcctt tgacaactcc acaatcaacc ggatgctttc
    73201 tttttttctt gtttcactta ctacaaagcc gcctaagact agtaagccaa cggctattac
    73261 actcataaaa gtggaaagaa catgtgtata aatgagtaag ctcatactga ctgctaatgg
    73321 aattgcacat ggctttttct cataaatcag tgcgtaagca taatacataa ctatcggtat
    73381 aaccgtaagt gcaatcgctt cagcaatagc agaacgatga taaatatcaa tcgtacggta
    73441 cccataaaat gtatataaac agctaaatat aaaagccgca tcgattcttt ttaaaaattt
    73501 tagtccataa tgaaacatca gcatgatagt acaaacattc aatagccaaa catataagat
    73561 ataactaacg attaaattat tacttatcca ataaaaaatg actgccggaa aaaaggtcaa
    73621 gtagggataa aaataattca ctccgctccc ataatgatta aacgtcgtaa aattgattgg
    73681 accagaaaaa attgaagata accctttgac tctagcaaaa tggaaggcaa tatcccccga
    73741 tgtagaaata gtatgaacat ttctaaaata attgattgaa taaagtccag caataattgc
    73801 taggagaatg gacaatatta tttttttctt tacttgcatt acttaattat atactccttt
    73861 catggattgc tttatctagt ataacttaaa ttttaaataa atcgttattt atttttactc
    73921 tcacttaaaa aagcactaaa attataagag agggaggtaa tggtctgaac accaagaatt
    73981 gttccaacat cgaattgctt aactaatgag ttcaaagctt aattatgtgg ctcttatatt
    74041 taccgagcgt ggattgcgat ctctttagcg aaacaaacat ctttcataaa aaaaacagcc
    74101 atatccgctt tcttggatat gactatttac tactacttta ctatctttca ttcttcttgt
    74161 ctcacttatg ataaggcgct gcgtatcatg agtgaatgat attaggaaaa cttcataaaa
    74221 taaatctttt atacatttcc acttctagat ggtcattcat gttagaagaa tcaaactatt
    74281 tttttactgt cgtaataata ttaaaacact agaacaaatc aattaaattc cataaaatat
    74341 aaataataga cctagcatca tctggtataa aatggatgct aggtccgtta tatttactca
    74401 aaattgattc tacgaataga tcttcttatc atttctattt tagtagtcat gcgttgttgt
    74461 tcttctaaag gtggtaatgg tataagtagt ttagataaat ttgtaccatt tacatttggt
    74521 tgcccagttc cgtaagaaat tttttctaat aacttccaat ataatggcga gtctaagaag
    74581 cagtctacgt attctgataa taatttctca actaacctaa ttcgaatcaa gtaagaagca
    74641 aaaacagatt cctcacttat ttccttaacc aagaaacttt ttcccatagt tcctcctgtc
    74701 cttgctatca aaatgtcatt ttcttccaat cttaaatcaa ctagtttaga attactaata
    74761 tcacagtaag gcacactgga ccaatttaca cgtccctctt gtatatctgt gattctcaaa
    74821 aacttaacat tgccttgttt tttcgccgaa tctgtatagc catattgaat cttagtagaa
    74881 atacttccta aataaaccca tagtcgaaca tcgctagatg atttttcttg tcgttcttta
    74941 tgaacaacag tgatcatctt gagttgtccg actatttttt agttgcagca atctttttgg
    75001 gacgcttatt tgcatgaagc aacgttgcta agtctagtaa taaaacattg gctaacacag
    75061 gattggcttt ctcgcgatac gctgcggcgc cactttcaaa caatactgct agacgatctt
    75121 ctacaacaac gatttgttcc aaatacggtg gaaatttgat tcgttttagg atccggctag
    75181 gagagtcccg ctcggacact aagagttccg aggtataagg accataagaa cgactggcta
    75241 agagataatg gccataaaaa gccacacctt gaatcttatc agatgttttt ctgctcattg
    75301 tcacggttgg ttggattttg tctttgcggc gaattgctgt tttcatttca gctatcgtcg
    75361 gcaatagata gaaagtcaac tgtccttcac cttttagtgt gaagttgcca gataccagtt
    75421 gatcattgtt ttgagtcaaa tacgatgctt gtggaatctc tgagagatca gttgtcagcc
    75481 aataagcgat tggctgtccc gtctcttcag atgtatctgc taagatatcg atcaaacgta
    75541 aagcggctac tcgtccagta gcagatcctg tgattgtcaa ccataaaagt tcccgttttg
    75601 tatcatatac taagccccct acatgtggcc gtttaggtaa aatcagcagt ttgatcggct
    75661 gtcctgtttc tctatccagt acatgaataa tagaatgatg ctgatggtca tagcagtagg
    75721 cagaaataaa cacaaaatct tgagaaaaag ccaacccttg cggcgtcatc cattgacaaa
    75781 cctcattttc gccggtttcc ggcaccacca ttcttgtttc tgttaatcca ggaatgttat
    75841 attgttttgc ttcagccttt tcccaagctg cttgaacaat aggataccgt tttaactttt
    75901 tttcaatatc ctgatgtatc cgttgctgct tccaatgctt aaactttagg acatagtaaa
    75961 caagaaggcc aatgaccagc aacactaaaa tcattattgc tacccgctgt gtcatttttt
    76021 tgcctccttg ttctattcga tcaatcgtcc atataccgct attaattacc gtaactacat
    76081 gtttctttta ctagcgtttc tttataggat ctttcataat ctcatttata gtaacattaa
    76141 gaatccctta ttctactata gtcacttcca catcaatatt gcctcttgtt gctttagagt
    76201 atgggcaaaa tgcgtgggct tcttctgcga ttttctctgc ttggtccttc tcaagtcctg
    76261 gcaaagaaac ttctaaaacg accccgattt ggtagccccc atcttctaat tgaaataaag
    76321 atacccgtgc tttgacttca gaatcagact caagattatt ttcttccagc atgtgttgaa
    76381 ccgcgccgtt gaagcaagat gcgtatccag ccgcaaaaag ttgttccgga tttgtccctt
    76441 cactatggat tcctgggcgg tcgatcttca tgtgcatact tccgtttggt gcctcaactt
    76501 cgccatcacg gcctccacga ttgatcattg ctgtttcgta catttttttc attgagatca
    76561 tcctttcttt cgtcgttcta tattaagtgt aacgagtatt ttttaatctg acaaaggtaa
    76621 tgcttgcatt cggcgacatc agttagacaa catcgatgat cagtgataga agcagtttat
    76681 ctatacaaaa aaagaagggt tctatgatat ttggtgtcct tactcgcctt gagtaacaac
    76741 accaaatatc atagaaccac ttaatcagct tcacactgct ttttctactt tcgtagttga
    76801 aaaaaactta aacaaatcat cggcaaatag ttaaagaaaa aacttaatcg ttgaaagaag
    76861 cccaattgct taaagaaggc aaactgacta atcgacggaa tccgtgctaa tccgtaaaga
    76921 cctgcaatta gtaaactaat aactgttaaa acaagataaa aatggctaag cgtaccttga
    76981 ccactttgac gataaagcag aacaagtaac aatgggaaaa gtagaaagcc tgcatagcct
    77041 agcccagaac ctatattatg gatccaagtc gatagattcc aagagctttc attcgtattg
    77101 atactgaata agccagtaaa aatacaatca cctatcccat ataaaccaac tgttgcaaca
    77161 acaagtattg caagtgtttt tgatgttcca acaaataggt gatacaacgc aggcaacgaa
    77221 agaacaaaaa aaagtccaga tacaactgac cagaccaaga aagcacgtct gactggacta
    77281 tctacgtcac caaacacact aattacggta gtcatttgat tcagtttggg ataaaaaagg
    77341 ccaaggatat acggtgtcga taaatcactc atcacaccta ataataaaaa ataaaaacca
    77401 tatttttgca aaaaaatcat tttcttcccc tactttttag tgattattcg atacatccaa
    77461 caatcaaatt ttttctcatt ttaacacata tttttattct agttgtcttt tgaacaatca
    77521 ataacataaa ggtgagtttc ttctacattt taaaaaatcg aatggcactg aagagttcag
    77581 ttgtcagcat caatctccta ctcaaaaagg caaaaaaacg taagtcagat gttgttgaca
    77641 tctcacttac gcatccattg attgaaaatt tcttagtaaa atctactagc ctaaaaattt
    77701 gaagacttct tctcgatcat acagtttaaa tactttctcg cataaaaatt gagtaattag
    77761 tgccgcaaaa acagggatga ctaaccaaca aagaacaaca agaaagccat ttagccctgc
    77821 atctaaagaa gccaacggac caacaagtcc gaccacgccg aaaccagcag aagcaggcgt
    77881 acctgaaata gaaaatagag cgacaggaat agctgtaatc actgcactaa ctaaacaagg
    77941 aataagaatc acaggttttc taaatagatt aggcatcatc atcttcatag cgcctaaagc
    78001 aatcgcaatt gtcacacctg acttattaac cttccaagag ttcactacta aaacaaaagt
    78061 ggttgcagct acgcccatcg cagccgcacc agcagaaaca ccatctagtt ggattgccat
    78121 tccgattgct actgttgaaa taggagagat aatcaaaaag gcaaaggaac aaccaatcaa
    78181 gatagacatt aacagcggtt gtaaggtagt gaagttatta atcaatgatc caattgcaga
    78241 agtaattgct gttacaaaag ggaataaata aaaaccaagt aaacctgcac ctacacctac
    78301 aacaatcggt gttaacacaa tcgacactga cccaaaacta tttccaatca gtaaaatcag
    78361 cccgacagca atcgatgctg tcagcatcgt attaataata tcgcctgtac cagcaccaac
    78421 gtaaacaccc gtttcaccca aatcaggtgt gaatttgact acaccagaac caacaaaaga
    78481 agctccggct acaaccatca ttctcatcgg atcaaatcca aattgtaagg caatcaaacc
    78541 accaatgatc aaaggtgttg ctagttgaaa aataactgct aactgtgcga tcgttaccgc
    78601 aaagggatac gcactaaaat attttaaaat ggcacctaat actgcattag gaatcaatcc
    78661 aataatgatt cctgttgctg taccagcgag gactttattc agaaaaattt tcggtgatat
    78721 tttttgtgaa gtttccattc aatctctcct ttattttacg ttcaaactat cttcttttgc
    78781 atggacaagc tcagtcaaga aatcacaata aggcgtcgca acaccatatt tcttcccttt
    78841 tctagaaatt gcgccattga tataatcgat ttctgttaat cgatggttct taatcaagtc
    78901 ttgatacatt gaaggataat gtaacccaat tgtttccggg tcaaaacaag attcacaatg
    78961 tgcaatgact tctgggacat ctagttcaat cttctctact gctgctactt tggcaaactc
    79021 attgacaatc gtcgccacca ttttatgagc agtcgatgtt tttcctagct cagccatatt
    79081 aacgtctaag attgtgcata gtccgttcat tgttccgttc acacatgctt tgcgataaat
    79141 agaatagtga atattgtcag aaaaatgagc atttaatcct gattcagaca atttgtctgc
    79201 taattttttt gcagctgctt cttttccatc acctaaattt tgtaattcta ctgaaccact
    79261 tccaaataat ttgacctgac caggaccttc aagacctgcc gtccacatgg tatttccaat
    79321 atagatattt tccattggta caaatttctc aataatatct tcatgcccga taccatttaa
    79381 tagacataag acctctgtat cttttttgat taatgattgg atatcctgca gcattttttc
    79441 cagctgcatc gctttggtaa atagaataat cagatcaact tgatcttctt tttctacttc
    79501 ggattgaaga acgattggta gttttgcttc tacctcttta ccattaaaat ttgcttgtaa
    79561 tccatgttct ttgatttgtt ggacatgttc tgcccagcca tcgattaata atacttcgtt
    79621 cccactttgg tgaagcatca acccaaagcg acttcccatt gcgccagcgc ctgcaattgc
    79681 tattttcatt gattcttcct cctttttctt tctattatac tcatttgaga atcttttcac
    79741 aacctcgttt tgttattctt ctcttattta tcatgtttat atccaccatt caagttattt
    79801 tatcagcaaa tcaataaaaa ctggaataga atcccaattt catcgtaaga gaaactagac
    79861 tagcaataag aaaatagaaa cattcataga aaaaatctca ctcctctgat tataaaagag
    79921 ggggcattaa cctcgtgtat actaaaacct tccattcatt cgatggatga ttttcttttt
    79981 gtgaaaaaat attcattgta gtacgatgtt gcgcaacaca gacggatggt attgcttatt
    80041 atttattaaa atcgaacaat acacttattt aaaaacttct ttcccagatt ttcttccatt
    80101 tttacagtta taactagtat tatcatgaaa aatagccttt tattgtctat gggaataata
    80161 atttaaaatt ggtacttttt tattaattag ttcatcgccc aataatctct ccagtttctt
    80221 agcatctcct gactcaaccg gaattatcca agcccagtct aaataatttt ttaaaatctc
    80281 atcatatttt gcaaatattt cattgccata ttccgtcctt aaaattatat tttcagtgcc
    80341 agacaagtga tttatattga gttgataaaa aagatctcca tctaaaaaaa tatcattaga
    80401 agaagatttc cccacagtaa tgaccattcc atcagctcta tgtgttacat acaaataatt
    80461 gtatgacctc atttcaccta atgaatcaat tatttcttgc cctttagctc taatatattg
    80521 atctctatta cctatctcac tcttatttaa caaaagtttt ttcatgtcaa atttaatcgg
    80581 ctgttttatt tttgtaaatt cgcttctact actaatccaa tccgagatta atttttcaac
    80641 atgtcccaga gtaaactctg atttattcgc taaatacttt ttttgttgta ttaaagacat
    80701 ctttccccga agctcaaaat tgagcctaca tcgattctct atctcttcaa aaagcatctt
    80761 atcttcatca ttcttatatt catcattcat aaaaccaatc cagctcctcg attaagataa
    80821 tattttaatc tcatacaaaa actagctctc atcaaaacaa ccattgtttt gatttctcat
    80881 gaaatttctt tatacttttc tccgattata aattcctaac cccttgagaa aattacgcat
    80941 atatttatct ccgcaaggct taaaatttcg ttggccttct tttctcaaaa atgccccgat
    81001 ttcgcctttt gatggataga tttctgcctc agcaaaaacg tctaaaatat catcagtggt
    81061 catagacaag gcgattttta atttttttag caacacattg ttgatatatt tgatttcctt
    81121 gcttttttgc ggcgtgtcta ctatcggctt atctttttgc ggaccacgcg ccaagagaat
    81181 caggccattt aggaatgcgt caaaaacttg gttgttgatg gttttttcat acacattatt
    81241 ttctgcatta tctttgttct tatcctgtac tttggtcagt accgcctgag cttcttcttt
    81301 agtcagtggt acaccgccta gctcaaaagc tttaatcaaa tccgtatctt tcaaatcaat
    81361 cgcataacgc aatcgcaata acctatcatt gttattcatt tgttcctccg aagtatttag
    81421 tctttacttt cttacgtact ttttgtcttg ctaagatttt taggatcaat gataaaaacc
    81481 gcatcactta tgataaggcg ctgggtatca tgagtgaatg atattgctga atacaaatag
    81541 tccgaccaca ttaagttgat cggacttcat aagcatttta ttgactaata cttttttgct
    81601 taagaattga ttctaacatc ttttgctaaa gttaagcatc ctatagttcc tgcattatct
    81661 gctaacttag gtgtgacaat gtattcttcg atatttggcg tatcgacata gccgttaatt
    81721 agttctaaaa aacgtctttg tactttcttt ttcagatgtt cttgttgcat gacaccacca
    81781 ccaaaaatta taatatctgg tgaaagcatc agggtcgtat tacaggcaca ttgtgcaata
    81841 taatccgcct cgatttccca gaacggatct tctatagaaa gatcttgtcc cttggttccc
    81901 gtacgcatct cgatagcggg tccagatgcc aacccttcga gacaatcatg atgaaaagga
    81961 caagtaccag agaaagtatc tcctgaatgt ctcttaacta acgtatgccc catttctgga
    82021 tggctaaacc cttcaacaaa aatcccatct tgtatagctc ctccaccaat tccagttcca
    82081 acagtgtaat aaacaacact ggataaacct tttccatgac ctgaaacata ctccccgtaa
    82141 caagcagcat tcacatcggt tgtccaggca attggaattt cgaaatgctt attcaacgtt
    82201 ccaacaaaat caaaattttt ccaggcagtt tttggagtag aggtgatatg tccataggtc
    82261 tttgattcac gatggatatc aatcggtcca aatgacccta ctccaatgct ttctaattgt
    82321 tctttatagt gattaaagaa atcaattacc aaactcattg tttcattcgg tgtagttgta
    82381 ggaaaactca ctctttctaa aacctttaaa tcatcattgc caatggcaca aacaaattta
    82441 gtcccacctg cttctattga gccatacatt tcttactcca ccgtcctttt atctaggaat
    82501 tcgttcttcc ctgtctaata gtttttcgaa aaactcatgt ggttcctttt ggtaccaata
    82561 ggcaacagaa gaaatatcgt cttgacgctc ataaagcttg atgtcatcat ttcctagggt
    82621 ttggaaagta acacgtaaat tttctttgaa actaatgggg tcgggtaaat gccagcggta
    82681 caacccatgc atcggtaaag catcatcgcc aaaaccatga actggatttg gattaggttt
    82741 tccagcacta aaataatccc gggtgtgatc tcttttagat tgaaaaggat agcccataaa
    82801 tagcgtatta aaattttgag catatgccct ttctccaaag ttctttttat ggaaagccca
    82861 agcgccgcca aaataatctt ctgctcctgt agatgttatt gtagggaaat cttcatctcc
    82921 atctatataa aacttaaatt ctccttcccc ccaccagtat ctttccaatg cgcacaaagc
    82981 aaagtaggtt cctacataat acccagtgcc tttgattcca tcaataaggg tgtaatcttt
    83041 tccttttgtc gtgatgggtt cacggttcca tttagcatga aaatacatcg catcatccgg
    83101 tacttcagtc aatgcataat taaatgtata aaaaatgtgc ttaataaact caggatgttc
    83161 attcgttaaa gtaatcttag ctttttttcg aaatggcatc tcaaaatagc aattcatccc
    83221 tgatgttgga ttcactacga ttggtaagga attcacttcg catcttgtcc caaacccatt
    83281 acaaaaaaaa tctcctaatg gactttctac agaaggagtg gattcatcat cccaataaat
    83341 acgcaaaatt aaatcacgta agacgaaact cccagcgatt gttttgtctg tcactgtcat
    83401 ccaaaaatga cgtaaaattc cagggccttc catttctgct aaagtaattg tctctccagc
    83461 atttatcgga acagaaggtg acccttttct cccaattcct agatgactcg ctgtcattgc
    83521 cgctttccct ttttcaccat ttttattttc tggtgaaata gttctacttt cctctccctt
    83581 gtggagccat atattattta aacaattcat tttattcgtc ctctatcctt tcttcacttt
    83641 tttgattatt catatagatg atttgttgtt gtgcctccgc aataattgct ccaatatcta
    83701 aattatcatt tcctaactgc aaagcgattg acattgccaa gggaagattc attcctgcaa
    83761 ttacgtgcac tctgtcagaa atataggtaa aaaacttttg atttacactt cctccagcca
    83821 tgtcagttaa aacaattatt tcgtctgtag tatccactaa ctctttaatt tgttcatcta
    83881 tatcatcaat ttcttcgaca tatgcacata agctactaat ttgattatgc atacctgtta
    83941 aaaactctag tgtctcttta aaaccctcag ctagtattga atggctagca atgatcaatc
    84001 ttctcataat tcaaatcctt ttcctttacg ctaatattcc aaatgcagcc ataaccatcg
    84061 caaaaacaat aacgagtaga atcaaaatgg tcatactgat ttttttctta ctgagtagat
    84121 aatatgctgc agcagtaata attactggaa ttaatgttgg taaaattttg tccaacattg
    84181 gttggatttt catactaact tcaccaaaag tgaatttaag tggcgttgaa acactgataa
    84241 ctgaagcaat taatgatcca actactgtta gccccaatac tgaagcagct tcagttaaat
    84301 aattaatctt ttcaccgtat tcagtaacaa tcttcattcc ctgcttataa ccaaattcaa
    84361 agcctctcat tcggaaaaag aagattacca tgattaaaat gaaccataaa aagattccta
    84421 caggattatt ttctaaagcc atataagccg caattgatcc catgatggtt gggatcatcg
    84481 tcatcaaaag agagtcccca ataccagcaa ttggacccat cgtaccaact ttaaagtcat
    84541 taatcgcatc ttttgcttct aatccttgct tttcctccat tgcaacacaa gcacctaaaa
    84601 taatggctgc cagccaaggc tgtgtattgt aatactgaaa gtgattattt aaagcttcga
    84661 tgtattcatc atcatctttg tataattttc ttaaaatagg tgacaatgcg taagtcacag
    84721 atgcaccttg ctgtgtttga taattaaagg tacaaactga catcaaccaa cgatagttcg
    84781 ctttcctaag atcctttttc gttacttgat atttttcgct cattttattc atcctcccca
    84841 ataaacccaa catcagaagc tcccgcagaa gcagtgattt gtgcatcttt ttcagctcta
    84901 tgatacacat taaatgctaa agcgaatcct atgatcgccg ctccaataat aggtaccttc
    84961 aaaaaagcgg ctaagaaaaa tccaacaagt aaataactaa tgtatcgacc tgtaggcata
    85021 aagcgtaaca acatcgcaat accaacagca ggcaacattt ttccggctaa tgttagccca
    85081 tccataaacc aattaggtaa aacatccaaa acgtaattaa cagcagactg tcctaaagta
    85141 acggcaataa atactggaat tgctgcagat aaaccaaaga aaattggccc caaccacaaa
    85201 acactattca ttttcttaaa ttctcgttta ttcgcatatt cctgtgattt gcgaacaaca
    85261 aaaccattta agattttgac aattacatct agttgcaccc ctaacatacc tacaggtagt
    85321 cctattgcta atccggcttc tactccaagc tggctaccaa atgccgttgc aataattgcg
    85381 cacgttccat agtccggtac agatgagcca ccaaaaccgg caactcctaa tgacatcaat
    85441 tgaactgtac cgccaactat caaacctgtt tttatatcac ccatcaaaat tcctgtgaat
    85501 aatccccaaa aaactgcgta atttacaaag atcatcggaa tcccataata atcaacatgt
    85561 ttaataaatg ctaatatagt cagcataata atttgaaaaa tagtaaaatg cattatcctt
    85621 actcctttat cctaattttg attgaatttc ctgtgcctta tccgccggaa caaattgtgt
    85681 aacaatttct acaccagaat ccaacaattt tttatacgtg ctgatatttt catctgatgc
    85741 ataggctcta gaagatagct gtaatgcatt atctttaaca acagtaccgc caacaattag
    85801 tcggtcaatt ctaataccgt tatctactaa atgaaggatt gtttccggct ctttcacgat
    85861 gacaaatact ttttcctgat cgtatttccc ctttttaaaa ttcgcaatcg ctgtttcttc
    85921 agtgataatt gatacagcca ttccagcagg tctagctaaa cgcatacttg atttttggat
    85981 gtcgttattt gcgacagaat catcgatcac catcactctg tttgctttag acattggtgc
    86041 ccattgcgtg acaataatcc catgcaataa acggttatca actctcgaca taacaatact
    86101 cataaatact tcctccttta tctttcattt tcttacaagc aattaccatg ccaaaacaaa
    86161 aagaacttga taaatcaagc tctttttaca taatcataaa cgtatttaac ctcatgaatc
    86221 gggatgtcga cactataata atgttcaacg acactgaaag attgcttaaa atgtgtctga
    86281 aatttttgaa attcctcact cgtttcattg aaataaattt catcttccaa agtattttgt
    86341 tttactaatc gttcaattaa gcaactaatg tgaacatata atccgaaaca cgtattatta
    86401 tcaaatgaaa ttcctagatc attttgtaag atgtatatag catctgaaac ccgttctaat
    86461 aatttagtcg gatttaatat ggtcaattgc tccattaaat tcgttagact aaaattcttc
    86521 agaatattat tgttcaaaac tttcagttca ttatcattaa agtgtctatt caattgattg
    86581 gagaatttac ttatattcat tcctaaaatc atatcttcaa ttgaaaagaa ttctacatct
    86641 tctagatgtg gatttagtgt tccaacaata aaaagaatat tgttctcttt acgaagctcc
    86701 gataaatagt tttcattcac taaagagtaa tagtcacacg tttctatgac aagatcagta
    86761 tcccttggaa agctatcttc aagtatcttt tttaatttaa acgaagttcc taatccgctt
    86821 gcacaagaac agacaatcat atccttctta atatttgatg attcataaat ataatccaca
    86881 ttttgatttt cttttacttg ttcaagaatc tgtttaagcg gtaaatctaa taatatctga
    86941 tttgcaacat caatagccat tcttgttgaa acattgttta gtagtccgaa ttttttttga
    87001 gcgtctagtt ccaaatttag ataaattttc tccagtgaac ccatatcaac aagtaaaata
    87061 atttcttcat atccggtaca ctcttgtaag tatctattaa ttttgtctgc aatctcacta
    87121 cttgaagtca ttagtggcat atcaatggcg tcgtatatat atctctcaac gatcctatta
    87181 gcagtacttg ctatacaggt tgccgttaga tctccatgag ccaaaatcag tgctaaacgt
    87241 ttttgctgaa attctttact acacattaac ttaaataaaa taaccaaaac atttttttga
    87301 atttttgtta aataaatatc ccctatttga ataaaacgat tgactaattg aacttctcga
    87361 ctacaccaac tattaatatc attgatgaag gaatataatt tatcgtccga tgttaattgg
    87421 atttgataaa tccaagaatt caaaaagata gacgttattt gaagataata atagtcaaat
    87481 tctatttgaa aatctctctc tatttcctta acatactgtc taaatcgaat ctcttgatag
    87541 gtgggatatg ttaaagctga attattttgg atatcaacat tcttttgtct aaaatatcta
    87601 tcatatttct caaaaagctg ctgcttatca gtgtctttct tccacgtttg ataaagatac
    87661 tctataagtt cgttgatatt aaaaacttcg tctacttttt ccaaatcatc catttgaata
    87721 tattttaatt cattctgtct tttcataacc ttcatgccgt tgaaattcac ccattgtggt
    87781 aaatgataca tctgaatata aagttcttcc aaatcatcta agaaataaaa ggcattggca
    87841 caggtcaatt gaatgatatt tttcaaattg ccaacatttt cactaaagcg atagtttaat
    87901 aaaaaatcta ataattgttg agatatcagt attttctttg ctagtctttc ttcttctgat
    87961 ttaaaaaata tcttgattaa ctgttttctt tcataaagag aacgactgtc taatgttgga
    88021 agtgttagct ttacaggtat tcttctcaac aaagttgata atagtttatc ctcaggtggt
    88081 tctgatgttg caaatataat ccagcaactt gatgtgtacc agttttcatt atcacccatc
    88141 cgatgaaatt tcctcgtatc cataaactga aaaagtttct cctgacattc attgctcaat
    88201 gcatgaattt catctaaaaa taagactcca ttattagcta attctgctaa accctttctt
    88261 ccatcttcgg ctcctgtata tgcacctttt acatgcccaa aaaaattgga caagaaaagt
    88321 tctggattat tggcatattc actacaatta actgaaatga aagatgcctt ctcttctata
    88381 taattattgg ccaacaaatc cttatacaca taatttgcta aatagctttt tccagttcca
    88441 gtctcgccat gaagtaaaat gggtaagcca tttggcggat agtagattgc tgctttaatt
    88501 tgagcaatta catttcgcag acttccttga cttccgataa ccctttctat tccaacccta
    88561 aaagagctat cataccattt ttccgcttcc tctgaagagc taaaaatttg ttgatttgga
    88621 actttctccg gtaaagaaaa gaagattact ggacgagtat tgatttttcc aaattctcca
    88681 tcttttacga attcattcaa atattgagag acaatattac gactaacatt taatttttca
    88741 gatattttct gtgctgtatt gttcccccat ttatttttaa tctcagagtt ctctatgaca
    88801 taattgacaa tgcgttcttt taattcttcc atcacagcac ctcctcgaca ctattcgaat
    88861 tttgccgaca gtatttttcc ataaatatga cttgctaaaa aggctttgtt tagatcattc
    88921 aattggaacg ttgcttgttt tgcttgatcc gctaagacgt tgaaaagata ctctggcgaa
    88981 atcgcatacc ccaaaatatc aacgattgtt gcaatcagat cttcttttga ttcttcatct
    89041 gaaagtaatt cacgatacaa catcgtttgt ttgcttactg tgtcatattc ctctaaggat
    89101 tcatctgcta aaagaaccac ttgttccaac aaacggtcgg ataaatattt atagaaaatc
    89161 agccccaata aataattttt atattctgac gcatccattt tactacggag attatctgcc
    89221 gcactaaata acttctgatt taattctgca cccaaaaaga tacactccta tctcttattt
    89281 aaagttgcta tataccctct tattttagca tactcagttt tagaaaaagc aaaaaaataa
    89341 agaaacttat tcttgataac aagctacgtg acgtatatcc ctaacacaaa aatagccata
    89401 tcctttggtt tggatacggc tatttgatat tactcattca attatcaaat cacagtaggt
    89461 gtgaatctca tcgggatcgg caatatctac ttctgattag gatcaaaggt gattttctca
    89521 ataaaggtgt gatacaaagc tttaacttgc ttcttctcac tctggataag aaagcaatcc
    89581 aaactagtca atatctgttg gacatctttg acttgaatcg gttccccttg ttgttgaaag
    89641 atccctaaga tttcattctc tcgaatttgt aactgtcttc gtttttcagt caattcattt
    89701 aaacgatctt ttaacatcgg aaacaattcg ggactatctt ccaaagcagc ttcctgtttt
    89761 tgctctaata gttagatttt gcgtaccatt ttcttctttt attttccttc gattgctgat
    89821 tttaatatag tctaaaggaa atttatattt attgtattct ttataacttc aagagaactt
    89881 cgtttgagta ttactgtatt tttttaattc cataagaaaa ttagttatta cctgccacct
    89941 aatcagcaaa tctgaacctg agtcaatata attaatatta ttttccatct ccaacattgt
    90001 aagtactgtt ggtgttaata tagggacttt gtacaattgt atttttttga ttttatcatc
    90061 tgcacaaagg agatttttta aatctaatcc ttcttttatt tcaaaagttg aattttttaa
    90121 atctataaga gtaaaaccaa ttccttcata ctgaatttct gaaaatcgaa tttttctccc
    90181 agttgataga tcaaggggca gaaaaccttt tattacattg tgagtgtcac catcatttac
    90241 aatgtcatta ggaattttga ttttagaatt ctgtggagca cctattggaa gataataatt
    90301 cattataatt ttgtagtctt catgaggaaa taaagtactt ttaggattgc taagatattc
    90361 tcgtaccgaa tctaagaatg gcttatccat tgaatcttca tccccattta aactaaaaaa
    90421 cattcctaca attgcttttg caactctaag tgaattcatt ttctttattg aatgtgttaa
    90481 atcagactta ccattcttta aacttgtatt gttataaagg aaatttttat tgtcttctgc
    90541 aaatctaata tattcctcaa catactcact accaaaaaaa ctattacatt tactacataa
    90601 cgtattggaa tggcaacagt ttttttgaca aattttata
//
LOCUS       DACGMI010000005        72636 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.005, whole genome shotgun sequence.
ACCESSION   DACGMI010000005 DACGMI010000000
VERSION     DACGMI010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 72636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.005"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            14..1141
                     /locus_tag="IXT46_000418"
     CDS             14..1141
                     /locus_tag="IXT46_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4946363.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1359..2501)
                     /locus_tag="IXT46_000419"
     CDS             complement(1359..2501)
                     /locus_tag="IXT46_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4946364.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2506..2691)
                     /locus_tag="IXT46_000420"
     CDS             complement(2506..2691)
                     /locus_tag="IXT46_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAQ4946365.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(3045..3290)
                     /locus_tag="IXT46_000421"
     CDS             complement(3045..3290)
                     /locus_tag="IXT46_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4946366.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3284..3685)
                     /locus_tag="IXT46_000422"
     CDS             complement(3284..3685)
                     /locus_tag="IXT46_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4946367.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3872..5680)
                     /gene="uidA"
                     /locus_tag="IXT46_000423"
     CDS             complement(3872..5680)
                     /gene="uidA"
                     /locus_tag="IXT46_000423"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HAQ4946368.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5703..7469)
                     /locus_tag="IXT46_000424"
     CDS             complement(5703..7469)
                     /locus_tag="IXT46_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HAQ4946369.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7482..8276)
                     /locus_tag="IXT46_000425"
     CDS             complement(7482..8276)
                     /locus_tag="IXT46_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAQ4946370.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8286..9662)
                     /locus_tag="IXT46_000426"
     CDS             complement(8286..9662)
                     /locus_tag="IXT46_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4946371.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(9782..10429)
                     /gene="eda"
                     /locus_tag="IXT46_000427"
     CDS             complement(9782..10429)
                     /gene="eda"
                     /locus_tag="IXT46_000427"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAQ4946372.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10513..11940)
                     /gene="uxaC"
                     /locus_tag="IXT46_000428"
     CDS             complement(10513..11940)
                     /gene="uxaC"
                     /locus_tag="IXT46_000428"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAQ4946373.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(12014..13093)
                     /gene="uxuA"
                     /locus_tag="IXT46_000429"
     CDS             complement(12014..13093)
                     /gene="uxuA"
                     /locus_tag="IXT46_000429"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAQ4946374.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13096..14727)
                     /locus_tag="IXT46_000430"
     CDS             complement(13096..14727)
                     /locus_tag="IXT46_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAQ4946375.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            15031..15702
                     /locus_tag="IXT46_000431"
     CDS             15031..15702
                     /locus_tag="IXT46_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4946376.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(16427..16762)
                     /locus_tag="IXT46_000432"
                     /pseudo
     CDS             complement(16427..16762)
                     /locus_tag="IXT46_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16859..17311)
                     /locus_tag="IXT46_000433"
     CDS             complement(16859..17311)
                     /locus_tag="IXT46_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946377.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(17318..17866)
                     /locus_tag="IXT46_000434"
     CDS             complement(17318..17866)
                     /locus_tag="IXT46_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4946378.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(17911..18243)
                     /locus_tag="IXT46_000435"
     CDS             complement(17911..18243)
                     /locus_tag="IXT46_000435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946379.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(18257..18487)
                     /locus_tag="IXT46_000436"
     CDS             complement(18257..18487)
                     /locus_tag="IXT46_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946380.1"
                     /translation="MCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQKGYPYGPTN
                     LKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(18709..19251)
                     /locus_tag="IXT46_000437"
     CDS             complement(18709..19251)
                     /locus_tag="IXT46_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946381.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(19272..20363)
                     /locus_tag="IXT46_000438"
     CDS             complement(19272..20363)
                     /locus_tag="IXT46_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAQ4946382.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(20371..22581)
                     /locus_tag="IXT46_000439"
                     /pseudo
     CDS             complement(20371..22581)
                     /locus_tag="IXT46_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22597..25125)
                     /locus_tag="IXT46_000440"
     CDS             complement(22597..25125)
                     /locus_tag="IXT46_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAQ4946383.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(25177..25587)
                     /locus_tag="IXT46_000441"
     CDS             complement(25177..25587)
                     /locus_tag="IXT46_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946384.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(25600..25818)
                     /locus_tag="IXT46_000442"
     CDS             complement(25600..25818)
                     /locus_tag="IXT46_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946385.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(25815..26807)
                     /locus_tag="IXT46_000443"
     CDS             complement(25815..26807)
                     /locus_tag="IXT46_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4946386.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(26886..27797)
                     /locus_tag="IXT46_000444"
     CDS             complement(26886..27797)
                     /locus_tag="IXT46_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4946387.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(27816..28160)
                     /locus_tag="IXT46_000445"
     CDS             complement(27816..28160)
                     /locus_tag="IXT46_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946388.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(28180..28736)
                     /locus_tag="IXT46_000446"
                     /pseudo
     CDS             complement(28180..28736)
                     /locus_tag="IXT46_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(28817..29317)
                     /locus_tag="IXT46_000447"
     CDS             complement(28817..29317)
                     /locus_tag="IXT46_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946389.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(29318..29863)
                     /locus_tag="IXT46_000448"
     CDS             complement(29318..29863)
                     /locus_tag="IXT46_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946390.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(29860..31116)
                     /locus_tag="IXT46_000449"
     CDS             complement(29860..31116)
                     /locus_tag="IXT46_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4946391.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(31477..31788)
                     /locus_tag="IXT46_000450"
     CDS             complement(31477..31788)
                     /locus_tag="IXT46_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946392.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(31811..33121)
                     /locus_tag="IXT46_000451"
     CDS             complement(31811..33121)
                     /locus_tag="IXT46_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAQ4946393.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(33735..34187)
                     /locus_tag="IXT46_000452"
     CDS             complement(33735..34187)
                     /locus_tag="IXT46_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946394.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(34189..34554)
                     /locus_tag="IXT46_000453"
     CDS             complement(34189..34554)
                     /locus_tag="IXT46_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946395.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(34653..38936)
                     /locus_tag="IXT46_000454"
     CDS             complement(34653..38936)
                     /locus_tag="IXT46_000454"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HAQ4946396.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(39083..39322)
                     /locus_tag="IXT46_000455"
     CDS             complement(39083..39322)
                     /locus_tag="IXT46_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946397.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(39412..39684)
                     /locus_tag="IXT46_000456"
     CDS             complement(39412..39684)
                     /locus_tag="IXT46_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946398.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(39767..40018)
                     /locus_tag="IXT46_000457"
     CDS             complement(39767..40018)
                     /locus_tag="IXT46_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946399.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(41014..41925)
                     /locus_tag="IXT46_000458"
     CDS             complement(41014..41925)
                     /locus_tag="IXT46_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4946400.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(42121..43956)
                     /gene="lepA"
                     /locus_tag="IXT46_000459"
     CDS             complement(42121..43956)
                     /gene="lepA"
                     /locus_tag="IXT46_000459"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAQ4946401.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            44103..45323
                     /locus_tag="IXT46_000460"
     CDS             44103..45323
                     /locus_tag="IXT46_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4946402.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            45343..45837
                     /locus_tag="IXT46_000461"
     CDS             45343..45837
                     /locus_tag="IXT46_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAQ4946403.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            45830..46501
                     /locus_tag="IXT46_000462"
     CDS             45830..46501
                     /locus_tag="IXT46_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946404.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(46652..49261)
                     /gene="clpB"
                     /locus_tag="IXT46_000463"
     CDS             complement(46652..49261)
                     /gene="clpB"
                     /locus_tag="IXT46_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAQ4946405.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(49512..50558)
                     /locus_tag="IXT46_000464"
     CDS             complement(49512..50558)
                     /locus_tag="IXT46_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAQ4946406.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(50569..50841)
                     /locus_tag="IXT46_000465"
     CDS             complement(50569..50841)
                     /locus_tag="IXT46_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAQ4946407.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(50876..51784)
                     /locus_tag="IXT46_000466"
     CDS             complement(50876..51784)
                     /locus_tag="IXT46_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAQ4946408.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(51916..53148)
                     /gene="pepT"
                     /locus_tag="IXT46_000467"
     CDS             complement(51916..53148)
                     /gene="pepT"
                     /locus_tag="IXT46_000467"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAQ4946409.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(53163..54284)
                     /locus_tag="IXT46_000468"
     CDS             complement(53163..54284)
                     /locus_tag="IXT46_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAQ4946410.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(54281..54982)
                     /locus_tag="IXT46_000469"
     CDS             complement(54281..54982)
                     /locus_tag="IXT46_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAQ4946411.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            complement(55126..55566)
                     /locus_tag="IXT46_000470"
     CDS             complement(55126..55566)
                     /locus_tag="IXT46_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAQ4946412.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            complement(55695..56621)
                     /gene="dnaI"
                     /locus_tag="IXT46_000471"
     CDS             complement(55695..56621)
                     /gene="dnaI"
                     /locus_tag="IXT46_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAQ4946413.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            complement(56621..57994)
                     /locus_tag="IXT46_000472"
     CDS             complement(56621..57994)
                     /locus_tag="IXT46_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAQ4946414.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            complement(58017..58508)
                     /gene="nrdR"
                     /locus_tag="IXT46_000473"
     CDS             complement(58017..58508)
                     /gene="nrdR"
                     /locus_tag="IXT46_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAQ4946415.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            complement(58820..59152)
                     /locus_tag="IXT46_000474"
     CDS             complement(58820..59152)
                     /locus_tag="IXT46_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAQ4946416.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            complement(59204..59833)
                     /locus_tag="IXT46_000475"
     CDS             complement(59204..59833)
                     /locus_tag="IXT46_000475"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAQ4946417.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            complement(59797..60633)
                     /gene="mutM"
                     /locus_tag="IXT46_000476"
     CDS             complement(59797..60633)
                     /gene="mutM"
                     /locus_tag="IXT46_000476"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAQ4946418.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            complement(60678..63323)
                     /gene="polA"
                     /locus_tag="IXT46_000477"
     CDS             complement(60678..63323)
                     /gene="polA"
                     /locus_tag="IXT46_000477"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAQ4946419.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            complement(63449..64132)
                     /locus_tag="IXT46_000478"
     CDS             complement(63449..64132)
                     /locus_tag="IXT46_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAQ4946420.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGIILAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            complement(64125..64610)
                     /locus_tag="IXT46_000479"
     CDS             complement(64125..64610)
                     /locus_tag="IXT46_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAQ4946421.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            complement(64917..66251)
                     /locus_tag="IXT46_000480"
     CDS             complement(64917..66251)
                     /locus_tag="IXT46_000480"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAQ4946422.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            complement(66382..67143)
                     /locus_tag="IXT46_000481"
     CDS             complement(66382..67143)
                     /locus_tag="IXT46_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAQ4946423.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            complement(67159..67641)
                     /locus_tag="IXT46_000482"
     CDS             complement(67159..67641)
                     /locus_tag="IXT46_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAQ4946424.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            complement(67661..69841)
                     /locus_tag="IXT46_000483"
     CDS             complement(67661..69841)
                     /locus_tag="IXT46_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAQ4946425.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVLIEQVDTKKGRISLTMLSPYEE"
     gene            complement(69985..70716)
                     /locus_tag="IXT46_000484"
     CDS             complement(69985..70716)
                     /locus_tag="IXT46_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAQ4946426.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            complement(70785..71726)
                     /locus_tag="IXT46_000485"
     CDS             complement(70785..71726)
                     /locus_tag="IXT46_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAQ4946427.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            complement(71906..72274)
                     /locus_tag="IXT46_000486"
     CDS             complement(71906..72274)
                     /locus_tag="IXT46_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAQ4946428.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
BASE COUNT        21260 a        15239 c        11313 g        24824 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgaagatat
       61 caatgatgat ggctcaagaa aaaaagtgga gaaagttggc ggagacaccc gaccagaggc
      121 cgaagctgct ttacgaaaag ttttatcaga tattgacgaa acaggacaat actttttagg
      181 tacggatact cgagtaaaac aataccttga tttttggatg gaggaatacg ttaaactaaa
      241 tctaaaatac aatacctatg aaaactaccg atttaccatc aaaaatcata taaacggtta
      301 tttaggaaag aaaaaactta cggatctctc ccctgctctt ttacaaaatt tcatcaatgc
      361 tgaatttaaa aagggttact cgaagaaaac aatgactatt actcactctg tccttaagaa
      421 tgcgctgaat atggcggttt atccttgggg attaatcaag caaaatccta tgctgtatgt
      481 aaaaatacca aaatatgaag cacgaccaac gactaaaaaa gatctaaaaa tcatttctct
      541 tgaggacttt gatcatatgc tagaaattac tcctgaagga catcctttct atattccttt
      601 gaatattgga ttttatacgg gaatgcgcgt tggcgaagtt tgtggtctga cgtgggatga
      661 tgtcgatttt tcaaatggaa caattactgt agagaaacaa atggtaaaga atgacggcgc
      721 atgggtatat ggtacgccaa agacaagcag ttccaatcga acgattttta ttggacaaac
      781 cttgctagca attctgaaaa aacataagaa acaacaatta gaaaatcgaa tgaagtatgg
      841 aaagctctac attgattcaa atgcagtatg tacgaaggaa gacggtgagc tagttacgcc
      901 aagtgtagtg aaatggaata ctaggaggat atcgaatgca ctctccctct cttttaactt
      961 ccattctctc agacatactc atgctacact tcttctcgaa aatggcgcaa aaatgaaaga
     1021 aatctctgaa cgattgggcc acagcagaat ttcaattacg atggatactt actcgcatgt
     1081 aacagataag atgagaaatg aaacggtcga tatcatggaa aatcttagaa agaattcttg
     1141 atttttgcca ccgaaaaaaa ccaccggtgg caaaccggtg gcaaatccat gtaaacatgg
     1201 tttatttttt acactgtttt caaacaaacc cttgctattt cttcggttcg tcctcgtcca
     1261 ttttcgatac cgacagctag cttataaccc aaggtatatc aacataaaaa aataaaaata
     1321 ggctatgaca gcagcgtgac agcaaaaaag atggaaagtt aaatatcaaa cctcgtaatt
     1381 tcatttgcga gtgcttgatt tgtttctgga tataagtgtc catatttgtc caaagtagtt
     1441 ttaatagagg catgacctag acgcttagat attgcataga tatttttatt atgttcaatt
     1501 aaaaaggcaa catgcgagtg tcttaatcca tgcatatgaa ttggttttac tcctgcaatt
     1561 tcagctagtt tttttattct gcttaaaata gttcttggag atggcggtaa tccatcaaaa
     1621 gaaaaaacca attctatatt tttcccaatt gattgttgag tttttttcca tgtttttaaa
     1681 tcttcaacgg tttgtctgtc taacgaaatt atccgaatac ttgatgtatt ttttgtttca
     1741 gcaaattcat aatcttgtct tgtacggatg taaattgact tatttacgct acatctgcca
     1801 tttattaagt caaagtcttt ccattgtaac gctaagagct cctcactcct tacacctgta
     1861 acaaaaataa aacgcatcaa acgtttataa aattcttcat aaaaatcccc gtgataaaca
     1921 ctattatata ctttcttaaa ttcatcaact gtccaaaatt ctacttgagg acgctgagtt
     1981 tttattttac ctatagtatc tacaggattt tcttcaataa tttcaagtac aattgccctt
     2041 ttaaaaacta ctctcaactt attgaatatc tgtttaatat aatttggtga taatggttgc
     2101 tcaatgccct tttttacaac atggattttc gataaaaact gttgaaattc ctgtatatga
     2161 attggtcgaa tctttacaac ctgcatttct ccaaaaaaat ccaatgcacg ttgtaaaata
     2221 tgatctgttt tcatatatgt tttttctaca gttcccaact tataccaagg aaaaaaatac
     2281 tctcgataaa aatcatgaaa cgttattcct tgcagataaa ttccttgtga atcagaaaaa
     2341 ctttgtttta actcttcgag tccccttcta gcttctcctt gagttttgaa gcctcttctg
     2401 gtcacttgaa ttctttttcc aaagcgatct tgtcctaaag ttgcagaaaa aaaccaagtg
     2461 cctctttttc tgtctttata aacattcgca attttcctca ttttactatt cctcccaaga
     2521 aatatggaga acttcttcta aaattgaaat aggaattctt tttatttttg aattacgata
     2581 aaaaaagtat cctttctcaa ctaaaagttc tttacattcc ttgaagattt tattagcata
     2641 gtactgagaa aaacctagat taatcaaatc ttttcgagta gctgttttca ttatagcacc
     2701 ttccttactt tttttcattt atttctatca gctgcttttg tcaaaagcac ataggaattt
     2761 cacctctccc caagtttacg gcgagcctta cggaagtatc attatcccaa ctttaaatca
     2821 tcgcttttta ttgactataa aaattatttt agaatattta tcgctccttc tttacagcaa
     2881 gaaatcatgg cgcaactaaa atatgctcct taaagtgtta acgtactgat agaatctatt
     2941 taattttcaa tgaacaatag gttttctacc taaaagaatc tactaattcc ttaactatta
     3001 gaagattctt ttaaacagaa aaagtggaaa ggggattttt ttaattagtt aattttaaat
     3061 tttaagatcg cttctattaa tttaatttct agctgactta tcatatattc atctacatag
     3121 gtaacgaatt gacctacctc gttaaatcca tttgtcaaac ataacttagc catataagaa
     3181 tgataatgtt tgagtatcat cttgatcgaa attggatctc cttctagagc agataagata
     3241 atggatagtg gaactaatag gtactgccgc tttttagatt tatctaccat aggtcatacc
     3301 ccattttcaa ttgttcaact gccttctttc gttgatacca gataccactt gtgctcatat
     3361 tgagaatttt accgatttca gcatcattaa aacctgcaaa ataataaagt aggataatct
     3421 ttcttcttat ctccgataac tgatcaattg ctgctgataa cttttgatct gaaattaata
     3481 tttccattcc aaataagaaa tagacatctt gttcatcaaa atgagtttgg gaatacctgc
     3541 cttcatttga atctgccaat ggttcctcat tatcctttat gttagcgttt cgttttcgaa
     3601 tagacttagc ttcgtttcgt aatacttttt tacagtaggc atcaaattgg tgttgtatag
     3661 atatgtcatt gtaatgttgt tgcatgataa tatgctcctt tttccccctt tccactaata
     3721 caacaatcag aaagcccctt tttttcgaaa aaactagaaa aaaaacataa aaatatttat
     3781 cattctttaa acagaaaatc tttctataaa aaacaaaaaa aaacgattag gctaggctaa
     3841 tcgttttttg aacattctta aaaaatccaa attatttttt ataactgaaa ttgggtattg
     3901 atgaccatcg tttctgtaga tagtaagcaa tcattttagg ttttctatct ctagtaaaga
     3961 ttcctttctt atttccttgc actcttaaaa tcccttgact tgttgcaaaa tctgcaaaat
     4021 tccacacttg ttcaccaaca aaattttcac atgtatctat tacttcgtga tttgcttcgt
     4081 aataagccac ttgatactct tctgtaaaca ttgttggtac tgtatcatga aatccagcta
     4141 ctgtatctgc tccatattct gtaaacatta ttggcgtatc aggacatctt tccatccatc
     4201 catctagctc ttttttcaac agatattttg catgtgccag atcccctccc gaaacatacc
     4261 aaccataata acgatttaaa cataaaacat cgacaatatc tcctacctta caaacatctg
     4321 gcgttgattt tagataagta acgattgtta caggtctttt ctgcggatca agttctttag
     4381 ttaattcaac taaaggttca aaatattctt tagcaccttc ggaatccgaa tctggttcat
     4441 ttgcaataga ccacattaca acacttgggt ggttcttgtc gcgttctatc aattccttga
     4501 tcaccgtttt atgagaattt tctgttcgta tctctttcca cgtattatgt ttttccacat
     4561 tatcatctaa taaagtggcc atgaaattta aatgtaaccc tactgcaggt acttcatcaa
     4621 taactacaat accttctcga tctgctaatc gcataatttc ttctgagtaa ggataatgtg
     4681 atgttctaaa agaattagca cctatccatt tcattaaatt aaaatcttta atatttacag
     4741 cctcattcaa accacgtcca ttaacatacg aatcctcatg cttaccaaat cctttaaaat
     4801 aaaaaggttt attattaatc aaaaatttgc cattggtaac ctgaacactg cgaataccaa
     4861 attcttctgt ataggtatcg atcactttat tatcatcaat taaactaatt ttcatactat
     4921 ataaataagc gtctagaggt tcccaaaaaa ttggattctt aagctgaatc attcctttct
     4981 ttccttcagc ttcagctaca agttgagcct cttcgtcata tatcgctatt aagatttttc
     5041 cggtccattc tgtatcgata ttgaattcta cacttgcatc caaatcagtt attcttgtat
     5101 taatagtaat atcacttata tagtctttcg gagttgtata taacttaaca ggtctatgaa
     5161 tacctgcata attgaagaaa tcaaaattaa ctaagttttc cttttttata tccccatttt
     5221 cctgtactgt ttccttcata atccccacag gtaaagtact atcgtcaata atattgttta
     5281 cagcaactgt aattcgatta ttcccgtctt ttacaaaccg attaatttca gactcaaatg
     5341 gtgtaaaccc acctttgtgt tgagtaataa actttccatt caaaaaaact tttgcttcat
     5401 gtgttgcaga tccaaaacga agaactaatc tttcttctaa taatctttta ggaagagtca
     5461 cttctttttc ataccacacc catccaacat gatttctaat gttctctgtt tcaaataaat
     5521 cattataaga agagggaact gaaatcggat aactctcttt ttcatttatt ggttctaaag
     5581 caagttcttc ctgtaagtca tcatttgtat ctaatttaaa tctccagaga ccgcttaagt
     5641 caattacttg cctcgtctct gtcataatgg gatacaacat ataaaccact cctatctaaa
     5701 tattaaataa atgtatcctt taaaccacaa taagcatcta ttggacttac tcccttaaat
     5761 tcagaaagac ccattagttt gtccaccaat atttctaaag tttcttgttt tccatcataa
     5821 gtattaatat aagtctttac ttgaggtaca tcagccaaat gaaacggaca ctgtacagat
     5881 acaaaaattg ttggaatttc atgaatgtaa aacggtatat ccggagttcc tttacttgct
     5941 ggccagacaa ttcgttgaac tgtgcctgga ttaacattag ctatattaat gatcaagtca
     6001 tattttttag ttaaattttt aattggtctc ttagcagcat atattccagc tatattttta
     6061 attttttctt cttgcgataa tcctttcaat tcttcttcag gtgaaatgta tttttcaact
     6121 tcaaatcctt ttgctgacaa aatctgtttc aataaatcaa tggcttgagg tctatttcca
     6181 gcaactactt caccaaaccc accttttacc ccatgtacat ctactagtaa aatcctttta
     6241 tatttttctg gtacaatagg ccaaatatct tgtttatctt taactaatgt aattgcttgg
     6301 tcagccacct ctttaaaaat tgatttattt tcaattaaac caattttttc cagagcttct
     6361 tgcttaggta ataaaatttg ttcttttgct tttttgtgta atcccaattt agcttttaac
     6421 cctaaaattc tttttaaggc atctaataac cgatcatcag tgataattcc tttacgatag
     6481 ccttccatca tataattaaa gtcttcatct ggatcattaa aaaatagaaa tagatcacat
     6541 ccagctgcaa tagaagtggg caataattct gatcgtttca ttgccccagt cattcctaac
     6601 atatgactag catcagtaac tactaatcca ttaaatccga gttttcctct aagtaagtca
     6661 gtgattaatt cttttgataa agttgcagga agtaaatctt catctttcag atcaggatta
     6721 aaatgttttg aataagctgg catatggata tgacctgcca taattgaagg taatccagct
     6781 tctattaagc ctgagtatac ttttccaaaa gaattatccc attcttccgt acctaaacta
     6841 ttaatactaa aagatagatg ctgatctcgt tcgtcaatac cgtcaccagg gaaatgttta
     6901 gctgcaggca aaattccact ctcctgaata cctttcatat aagctaaact aagttctaaa
     6961 actttatcag ggttttgtcc aaaagatcga ctagaaatga taggatttct ccaatttcta
     7021 ttaatatcta caataggagc aaaactccag ttacatccaa tagccgatgc ttcaatccca
     7081 gaaactctcc ctaattcata agcatatttc gcatcatttg ttgcaccaat ttttacttct
     7141 acaccaactt cagtaccatc tgtacaagct ccgttaccac ctgcttccgt attagcagca
     7201 attaatagag gaattttact ttctgtttgt aagatatagt tttgatcata tacctcatca
     7261 gcagttcctg gattatatcg tacagctcca atatggtact gattgaccat attactcaag
     7321 taatttttat cacgactaga tcccatatta acaaacaatt gacctatttt ttcttccaaa
     7381 gtcatagaat caatcgtctc ttcaatccaa gaaatagcat cttcatctaa attatatggt
     7441 ttttttcgta aatctacttt tatagtcatt ttctttctcc tctacttatt agtaagattt
     7501 ttccaaaaag tatctatata tttttgttca atatctacat aatctcccga taaacattta
     7561 aataaaacat cagttcttaa gttttcccat gattcttttt ctttattgac caaaatagga
     7621 taaaagaaaa ctttattttt atttgcagct tctagatcac caggagaatc accaatcatt
     7681 aatatcttat ccaaatcaca accattttca attacacttc gaataatatc ttcttttttt
     7741 cctttatctt gacaacacag ttcatcaact aatgataata attcatgtct ttcccattct
     7801 tcttgaacag cttccttatt agctgagctt acaataatta tcttcccata ttttttcaga
     7861 gcttttatag tatctctagc acttaaaaag ggtttatcta atccttttgc ttgactaatc
     7921 tgttgattga cttcttccga ccattttaaa gcttttaata aatcctctga ctgagaatat
     7981 tctatttccc tcttcaaaga tggattagac aattcttttg ttagagatac ccagtgcttt
     8041 aatcgattaa tcgatgttac atcatttttt tctaatgttt taactaaacc taaaaatctg
     8101 tttattccac gagtctctga atataaatta atattattcc aatcctgtag gaatttttct
     8161 ctatgatgaa catcaaaaat ctctgcagca attggtccga aaaagagatt gtgtttataa
     8221 gtcatcgtat ccataacaca gccatctgaa tcaatacaaa atatccaatt attcatattt
     8281 ctctcctatt tatgtttttg ttttaaaagc tcgcaatttt ctaagacttt atctttagat
     8341 aatggataaa ggaaaaataa aattaatcct acaatcagaa aacaaattga tggaattaat
     8401 gttgaagcgt tatataactt ttctaaaaca tctcccgttt gtacatttgc taaagagtca
     8461 tagcctataa tagaaagagt ccaacctccg acgcctccag ctagagcttg acctattttt
     8521 ctagcaaaag aatataccgc atatacggtc ccatcttctc tttgatcaga ctttacttct
     8581 tgatcatcaa taacatcagt aatatttgcc caaataacag tattaaacac acccaaaccc
     8641 atatagccaa ccgaactaag aattaagaat acatacatat tactagcttt tatcaaaaat
     8701 aagatcaaat atactattgc tgaaaagaac attcctactg atgccagttc tttttttcca
     8761 tattttttac ttaaaaacaa agttaaaggc gaaacaacta ttaaaaccaa aataggattg
     8821 ataaaattca ttaaaactat tccctgtgca tcattatagt aatcaggaaa tacataatta
     8881 ttcatactca taattaataa ttgagcaagg agtaagaaaa tagccgcacc aattatagaa
     8941 agtaatgccc tatttttaac taaccctttt aaagatttta acaatgaaac tttgtattga
     9001 gattggtcaa ttcttactcg ttcagtagtt agtttataac atattaaata acaaataagt
     9061 gcacatatcg aaaatattcc cgcaacaatt gtaaaagttg atccaccacg aactatttga
     9121 gcgcctgaat catctcttgt ataaataaat aatggtgtta atacaccaat gaccaaactt
     9181 gctaaagtag ctccaacatt tcggaatgtc gatagcattg ttctttcttc tgtaatagaa
     9241 gtaatagctg atgccattga tccataagga atatttatag atgtgtaaaa aatactcccc
     9301 cataatatat acgtaacata catgtatact accttaacgc tcatagaagc tgaaatcata
     9361 gaagtttgat acattaaaaa acttgctaaa gcgactggac cactcattct taaaatccac
     9421 ggtttaaact taccctgctt agttgctttc gatctatcaa caatacgccc catagttaca
     9481 tcagtaactg catcgataaa tcttgctact aaaaataatg ttccaacggc agctccgctt
     9541 atccccaata cttttgtata aaagatcatt aaaaaagaac tagcaaaaat gaaagtaaaa
     9601 tcgtttccaa aatctccaaa catatatcct attttgtctc ttataccaaa ttttctttcc
     9661 atacaattct ctcccttctg ttgttaagcg ttttcattct gatgaaagta cgtactatac
     9721 tctgaagcgt aaagagtcag tatttatttt ttacatttca gagtattatt tgttttttct
     9781 cctaataatt ctttatctca taaaacttat ctatatattt actagctact cgacttactt
     9841 cttcaaaatc acctttttca acagaagcca ataaattccc acctacacca actgcaacaa
     9901 ctcctacttc aaaccaatct tctaagttct ctatacttac tccgccagta ggcattatat
     9961 ttacgtgtgg taatggagct tgataggctt ttacaatgga tggaccaaaa gcagaacctg
    10021 ggaatagttt aatgatatct acgccagcag taagtgcctc ctttatctca gtaattgtca
    10081 tacaacctgg taaataagga atttgatata aattacaaat ctcagctgtt tgtcgatcaa
    10141 aagatggact aacgatatat tctgccccag ccataattgc gatacgagca gtaaacgcat
    10201 ctaaaaccgt accggctccg attattacat ctttttgatc agcatatttt ttagcaattt
    10261 ctttgattat ttcttcagca ttaggaactg taaaagttag ttcaatccct ttaattccac
    10321 ccgcaataat tgaatttatt gctttaatgg cctcatcctt atttttccca cgtacaaccg
    10381 caatgactcc agccgcttct aacttactta aaatttctac ttttttcata tctatctcct
    10441 tcctttatgg atacatactt tgtctagctg tactaactta caaagaataa atttaagctt
    10501 ttatttcaag tattattttc tacttccgat ttcaaaaaaa ttaaaataat tatacgcatt
    10561 acgataacaa atattctcca ctatctgact aagatacatt tcatcatctg gaattcggcc
    10621 tgctttaacc cactcgctta gtaattgaca taatactcga cgaaaatact catggcgagg
    10681 atagcttaga aaacttcgag aatcagtcaa catacctgta aaattcgaca acaaactttg
    10741 ttgtgccatc gtagtcaact gttgacgcat tccttcagct gtatcattga accaccaagc
    10801 acatcccaat tggatttttt gaatcatacc cccttggaag ctttgcattg ctgttgctag
    10861 tggaagccaa tcagttggat ttaatgaata taaaattgtt tttggtaagc acccactctt
    10921 ttcagcggta tcgaacaatg ctacaacatt ttgtgtcaaa ctagcttgat cccccatcga
    10981 atcaccaccg acatctactc caatttgttc ctttaatata cttgaattat ttcttaaagc
    11041 atttaaatgc atttgcatcg tccaaccata tcttgtatac tcagacatca aatgtaattg
    11101 aatacctgta acaaattgtg caatttctga taaatggaaa tccgtttttc ctgctaaagc
    11161 ttttattaac agattgtcga gtattttttc atctgctatt tcataaaaat aagtattcaa
    11221 accgtgatct gctaatcgac agccaatttg atgaaaatga tccactcgtt ggctcaatgc
    11281 ttgcttcaac ccattaaagt ctttgattgg tatagccgct gtttgactaa gttttaaaat
    11341 atagttcgaa aagcctgatg atttgatact ccagacctta tctggacgga aagtaggtaa
    11401 taccttgaaa gaattatcct gtttagaaag ctcagtatga taccacaagt catctgtagg
    11461 atcatccgtt gtacagatgg ctttcacatc catcatctcc aacaattctt tcgggcgata
    11521 ggaatccgtt tgaatttttt cgttagcacg tcgccaaatt tctggtgcat tcttctcaga
    11581 aattgtcaaa tcaatatcaa agtaacgttg taattccaaa tgagaccatt caaaaatagg
    11641 attacctggc gccttctcca ctgtttttac aaaagctaaa aatttttcat aatcatcacc
    11701 tggaccactg atcaactctt cttctatacc attagctcgc atcaatcgcc atttataatg
    11761 atctccagct cctttatcat ttaaccatac ctgagtcaaa ttcttgtatt gcttattttc
    11821 tagcaaatat gctgggtcta aatgacaatg atagtcgata attggttggt gttttgcaaa
    11881 tttatgaaaa agtcttttag ctatttcatt ctctaataaa aagttcttat ctaaaaacat
    11941 atttaaacac tcctttcctt ccgttagttt ttagaagaga aaatttttcc tctaaataaa
    12001 ctcccttata taattattta ctcgccccct tttcaagcgc ttcccaaata ccatttaaat
    12061 aaactgcacc tagagctcgg tcatataatc cataaccagg tctaccggtt tctccccaaa
    12121 tcatccgacc atgatctgga cgaatatagc cattaaatcc attatcgtac attgttttta
    12181 atatcttata catatctaga gaaccatatt ctgatttatg cggcgcttcg taaaaatcga
    12241 gtccattgtc acttaaatat ttgatattac gaacatgtgc aaaaggaatc cgatcccgtt
    12301 gacaaaattc agatagaatt tcatagacat cattatctgg tcgttctgca atacttccag
    12361 tacataatgt aataccatta gaaggagaat ccactacatt acacaaccaa tctaaatcgt
    12421 cacgattttt aacaatacga ggtaatccga aaatggaata tggtggatca tctgggtgaa
    12481 ctgccatttt aatcccaact tcttcacatg tcgggataat tgctttgaga aaatatgcaa
    12541 agttctctcg taatttctct tcatcaactt ctttataggc ttctaataat tgcttaattt
    12601 gtgataaccg atgaggttcc caacccggca attcaaaatt attagtagaa ttttctactt
    12661 ctctaataat ttcctccgga tcagtaggga tattttttga aatataggct aacgtagaag
    12721 acccatcatc taaacgataa tccaaatccg attttaccca atcaaatact ggcataaaat
    12781 tataacagat aacctcaatc ccaaattctg ccaaattgcg aatcgtctgt ttataattct
    12841 caatgtattg atctcgtgtt ggtaaaccaa ttttgatatc atcatgaaca ttaacactct
    12901 caataacttt caaggtaagt ccattggctt cgacttcatc ttttaaagat ttaattcgtt
    12961 ctctcggcca aacctctccg gctggtatat ccattaatgt tccaacaatt cctttcattg
    13021 ctgggatctg acgaatttct tgtagtgaga ttttttcttc atttgcccca taccatctaa
    13081 aagtcatttc catagttact ttcctccaac ttctgttata tatttattga ttgttttacg
    13141 aactgcttga ggacctacta gcatttcgca aaagattttt tcagttttct ttcctacccc
    13201 aacttgatat aaatctaaac caaagatttc tttattttct aaaatttcct gtaccgcaca
    13261 atgaatcttt gaaggatctt gttcacctaa tttcaatact gataatttat cctgcaactc
    13321 taccaataac ggatcaggac ttggcacaaa attttcccct tgatcatcga ctgccagtaa
    13381 ataacgtaac caagcagcaa tagcgatagg aataaatgtt agattttctg catttccgtc
    13441 tttttcgaca tactttttaa ttgtttcacc atagcgaatc gctacttttt gagaagtatc
    13501 tgttgcaatt cgttgtggtg tatctggaat atagggatta ggcaaacgtt tattaattac
    13561 ttcatcaata aattgttttg gatcaataat gcctggattt tcaactactg gtaaaccttc
    13621 taaataacct attcctttga ttaaaccaac caaatcatca tcctgcatct ctgctgaaat
    13681 tgattgatat cctagcagac aacctgttac tgccaaagca gtatgaagtg gattcaagct
    13741 tgtcgtaacc ttcatgatgt ctgctttatc aaccgtctct ctatctgtca taatcacacc
    13801 agccttttcc aatttaggcc ggccatttgg aaaactatct tcaataacta aataatgaac
    13861 tacctcagta ttagtgaaag cagcaatatt ggtatgtttt tttgtgtgaa tgatatctaa
    13921 atcctcgagc cccatcatca atagatcttc ctttacattc tctgaaggat ttggcgtaat
    13981 tcgatcaatc atactccaag gaaaagtcac tttttcttta tcctttaaat aagcaataaa
    14041 tttttcagaa acatatcctt ctttttgcca agcttctgca atcgtaaaaa tactatcttg
    14101 aaaacgttga ccattctgtg agaaattatc agtagaaacc atcgcaatcg gcaactctcc
    14161 agcattaaat ctgctatata acaaggatgt tacaatactc atcgtatgtt gaggattgct
    14221 aggtccagat ttgatatcag ctttgactac cgaaaagaat tgccctttag aatcttttaa
    14281 actgtaacct ttttcagtaa tagtaaacgt tgtaaactgt aatttaggat cttcaaaata
    14341 tttaaccact ctttgatagt ccgctatatt cttcggattg caatataaac tatcagccgt
    14401 tactgccaaa agtctttttt tgagttcacc atctccactc ataacaattt ccaaaatgtc
    14461 attgttatag tcatgataag ctttttccac tacttcttca tcaaatgttt cacacacaac
    14521 tactcctgtt tctaattcat tttgatctgc taagcattga gcaatttctg catgaaatcc
    14581 tcgataaaga tttcctccac caaaatgaag ccatactgga tgttgctggc cttcttgctt
    14641 aacttctttg acatcaaaac acggcagtag aatctgcatt tcattgaatt cttcgataga
    14701 attttgccaa tttttaatcg aaaccataat taacctcctc aaactgatat gttagttttg
    14761 atacatttta tattttaaaa cccattgtaa ccgttgtcaa tataaaaagg gaataaactt
    14821 gcttttttct accatatcag aatgattgta ttttttattc agaaaaataa aatactcctt
    14881 ctttttggac tgattttatc gaaacttatt ttttcttttt ttcatgtatt cttttatttt
    14941 tataactagt gtattacttc aaaatttgat attatatggc atgaacagaa ttaaaatatc
    15001 agttaaaata aaagttaagg agcattgtgt atgacaatta aaactagtct ccaaaatcaa
    15061 gcttaccaat ctattcgccg acaaattatc tatgctgact tagaacctgg aaaaaaagta
    15121 tcagaaaaaa aattagaaga aacactttct attggtcgta caccaatacg tgaagcactg
    15181 attcaactcc gacaacaagg tcttgttgat acaattcctc aaagcggaaa ttatatctca
    15241 ttaattgatt tagattcggc caaaaatgct cgatttgtca gagaacattt ggaacgacaa
    15301 attatgttag agtgttgtgc caaaatgaat aaccaaaaaa aacggatttt agaaactata
    15361 atttcagaac aagaaaaagc tgttagtcaa aaaaatgctc gtagtttttt tcataatgat
    15421 aatttattcc ataaagcttg ttttgaaatt gcagagcgag aagaagtatg gcaatggtta
    15481 gaaaataaca atacacactt agaacgattt cgatggctac gagtaaaaac ggaaggatta
    15541 aagtgggaaa aaattatgga acaacattat caactatttg aggcattaac aaaacaagat
    15601 ccagaagaag ctaactttct aacatcgttg catcttcatt taatgcttaa tgagcaaaat
    15661 attgttttag ctactcatcc aaaatatttc aaaaatatat aacttttaac tctttttaaa
    15721 ttaaatggtt gttctgatca gaaaaatatc gcttgttttc ttattatgta atatatttca
    15781 taaactattc tgcataacaa ctattgtttg tactttttac attggataac taattatgac
    15841 tgctgataac ttttgatatt aaactagtat ctccaataca aataaaaaat agatatcttg
    15901 ttcatcaaaa ttagttcgtg gatacttacc ttcatttaca tcattcagcg gtttcccatt
    15961 ttcttttatt ctattatttc attttctaat agacttggct tcatttcgca atactttttt
    16021 tcaataggca tcaaattggt gttgtttaga tatttagttg tagttttgtg acatgataag
    16081 tatgctcctt tttctctttt ccactaatac aacgatcaaa gggtgctttt ttcaaaaaac
    16141 tagaaaaatc aaaataagat tcgtattttg attctatata tcctgtttca actacatctt
    16201 atatttcaca atagaataaa tagccttttg catagctgct taacttataa gaaattgcaa
    16261 tttacttctt caaagtgaaa acgaatatga gtaaaataaa attattcttc ttacagataa
    16321 ttaaaaatag cgcgtaacaa aaatcggcat tcaatcacat aattaggatt gatgccgatt
    16381 acttatattc tacgtatagt tttagtattc ttatttttta tcaccagtaa ccaattgaga
    16441 acagccctaa agcagaatag tcttttatct caaaacgctt aatttcaggc ttaggaatat
    16501 gaataatctt ttgagtatat tctttctctt ttaatcttac tgaagaaata ccactgccta
    16561 tcttttttac aaatatttca tttggtgtac agactaataa aacaatattt gtaatcaatc
    16621 cttgcactaa agaattaaaa ggaagactat ttaaaacagg gtgtgcataa ctataacatg
    16681 tgaagtagtt attttgaact ttaactttta aaaactttaa aaataatctt atttgttctt
    16741 ctaaacaatc atctatactc atataatcac tccactaatt aatctcccca aaaagacaca
    16801 gcattaagag atataccaac acaacagtgc aaataactct acatcttcct tcgcaacctt
    16861 atttcaataa accataaaaa ttatttttta atagaaactg aaaattaaaa ctagaaaaag
    16921 tagttttacc gaatgtaaga gcatcatcac catcaatata gaaatacatt cttttccagt
    16981 tacatttaat ttttaaacaa aattctcccc aaaaaggaac tttttctagt gaaaacttgg
    17041 taatctcttt gtaattaatt cttgttaaag aataattaaa cacttcattt ttacttgtta
    17101 ttttttcatt gactataact agttcatctg gtaaaaaaat taaccaacaa acatcgacaa
    17161 acagtaaatg atataatcca tttccacctc caagcatatt caatactggt gaacatgcct
    17221 tagaaacacg aatatagtta tggtttaaat agatattttc tttaaacatt gcttgtttaa
    17281 aagccatatg ctcttgttct aaacttttca taaactttta ctctaatgca cagctagcag
    17341 cagctgctgc aattcctgct acaatattta ccttagctaa ctctttagct gcagcttttc
    17401 ctaattgttt ttctgcaatt tttaataata aatccgcagc tttttcaaaa ttaaaagctt
    17461 ttaatgcttc aataaaatct ccctgcgtac ctatagccca agccactcct cctccaggaa
    17521 gagaattaat ggctacacat ccagcatatc gtttccaatc aactttctcc attctaggaa
    17581 caataatatg ttcataaaag actcttgctg ctcttccttg ttcgttatct tgactgattc
    17641 gttcacgaat agcaccaaaa tcctttatat ggtatacacc atgttcgtct aaaaaaccaa
    17701 ctgtatcaaa ataaaaagtt aattcatcta ctaatttatt ctttatttct aaatcaactg
    17761 tattcacttt ttctgtggca tacacacttg ttccagtact aacaaaagta cttaaaccta
    17821 ataagaaaac acctaaaaca ccaaatattt taattattct tttcataatt tctcctccat
    17881 aaaaaataag ttacttttta aatatcttgt ttatgaattc attccccaaa ggccttttaa
    17941 gattgataca gcagtccgtt cacttctttt agacttgtca tacaagtctt ttaaatgatc
    18001 ccatatcaga ctagtttgtc tatctagctt caatccatta aacgctaatg aacggttcat
    18061 tttttctatt actttagata aagctacaga aatttttata ccttcacaac gcgcatcttg
    18121 gatttcaata atagtatcat caattagttt ttgaatttct tgcctatcaa catattcaat
    18181 cttagaaaga gaatctttta aagctactaa tgattcaacg atttcttttt tctcttcaga
    18241 cattttcttc ctccttctag tgacccgtaa agccatgtag agcagagtcc attgaaccag
    18301 taattacact atctacaacg ccattccaat ttactctaca ttttccattt ttcagatttg
    18361 tcggtccata cggatagcct ttttgacatt caatgttcgg attataccag ataggattat
    18421 accattcagc cgcagaagca gattcagtcg atacaaacaa tcccacacca acaaatccaa
    18481 tacacatcac actatagcca attagttttt tcatctcgta tccatctcct aaaaaataga
    18541 atagttctta tagttattca taagacatat tttttccgtt tttgttttat cctttctgtc
    18601 ctataacaac ttttttcaag taaagaatga catagttttt cttaaaaaaa cagtctgttt
    18661 ttttctattt cttcggtgta taataaatat gagtgttcat tttttatttt aatacgcact
    18721 ccgtacataa taaatcttga tcgcatcaat cttttgagct tcttgatcta ctttcaattg
    18781 aagtaataca aattgagtaa ccttattcat tgtttcttct ccaaataaca aatattgatc
    18841 cggattctct atatcttgtg tcacctggta aagtttccca gttgttttca tttgtacatg
    18901 cgggtctaca tcaatactat tgtctttaat acaacgatct gtcatatagt ccctcacagc
    18961 ttgattgcgt ttataaacat ctgtgaaatt actccatttt ctagcaaaat cttttaagaa
    19021 attttttgtc atttcatcta tttgcatttg ttgcgctgtc tcgtcttcta atgaaccaat
    19081 ttgactgtta ctttcagtac tttgaagagt tccacttgtt tcttttactg cttcgattgt
    19141 ttcttctgtc gttctcaatt gtgttttttg tttttcagaa gaaaaccaat gacaaccagt
    19201 aagacctatc aaacataacc aactaaatac taaaattatc ccttttttca cgtttctagt
    19261 cactgccttt cttatttcac cttacgaacc agactacgaa tttttgtttg attgtacgtg
    19321 cgttgatacc gagccataat ccgtccttgc tcggcattct gttccacact agagaaatgt
    19381 tgtccgccat atgaaacatc tgttataatt ccggtgtgac catagattcc aggagacaat
    19441 gcaccacctg cttgccaatt caccacatct cctgcttgta aatcacttgg ttttgggttc
    19501 atgattactt gccaaccata ggttgtccag ttataatctt cccctattaa catcgcaaac
    19561 atgtgtccag aacccattaa ctgtgggcca cctaattgag atacatacca tgccgtacca
    19621 ccataacatt ccccattatt tacggatcgt ccaatgatcc gatccaaaac cttcgcattg
    19681 cctttacttt ttcctgcaat aagcgaagtt ttttttgttg gtaggctatt ccaatgcttg
    19741 atcgcaaaag tatcatattc cgttaagtta taggacgtta tgatactcat tgctcctcga
    19801 taatacggac tcccttcggt aatacctgct gccgcatagc ctccacgacc tagaatcaat
    19861 aaacaacttc caggatcttt attgcccaca cattgattaa agttgctttg gctcgccacc
    19921 ataaagccat aatagtcata acaagctttt aagttcggaa acttcatata gaaaccacct
    19981 tcagaaccac caattccacg tgcagaacct tgtgggtagg gacaaccagg aaaccaggta
    20041 atcccaaaaa agttcgtatc gtttcttcca gattgtgact gtccataagc tgattcatag
    20101 cctaattgag aaagaatcac actcggtaat aactgatact ttacagctgc accaactgct
    20161 gcttgcgcat gttcatctgt gattggacca cgtcctttaa tctctgaaaa aatcggtaat
    20221 ccttcggtat attccccatt aaaagcgaca gctagacctg tagcttctcc tccatgctca
    20281 gaaagttctc ctgaaaaaaa gaatggcaat agaaaaaagg gaagaataaa gaaaagaaga
    20341 caacctagac accctttctt catttcttcc tcatcctttc ttcgataatg gtttttggac
    20401 tgttcgtcct tttggtaaag taaaatcagt tcctggtttt gcgtccaaaa tcggcagtgt
    20461 tttaggatcc ttttctattt tttccgattg ctctgttggc ttatctaaag aagaaaatgc
    20521 aggttgtaac gattttggtg cggaaatcga cggtttactt tcagacgaac gttgccccgg
    20581 ttgttgcaca gaacgatttc ctgatagagt ggctaccgac gaattaggaa cagagtattg
    20641 gttcaataac tgctgcattg ctggataact cccatttttc gcctgatttt tcacttggcg
    20701 aatctgttgt gaaagagaac cagcagctgt taattgtggc acgggtactt ttccagaagg
    20761 caacggaatc gattgaccaa caaaagcgat acctttattt aacaatggtt ttctttgatt
    20821 attcccttgt tgcttactca attgtgccaa tgattgtacc tgttgttttg gtcttactga
    20881 attcatggac gaatttggaa tcaaaccatt tgaaagacca gaattccact ctgttttcga
    20941 tttggtagaa gacatttcag gctctacccc atgataacga acatgacgac cactataagg
    21001 caaggcttga tttgaacgcc cacctagttc aaagggatta accacttgcc tcccttttac
    21061 cgattcttgt ggtgtacgtt tttgttgaaa cttttgaaat ccatgtatcg ctgcagaagc
    21121 gagtggattc gttgctcgat acacattccc tgctaatcct gcacctttga ttgccaaatt
    21181 ttgtccagca gttgatagtt gaccaggcag ttgtttcatt tgagacaaag aatgacttgc
    21241 tatgtttttc gtgttgttta tagtttgatc tgcagctcct aaccctagtt tctttaataa
    21301 atctttccgt tttacaatga gtaaaattga taggagtgct ttgacaaaca tatttcctaa
    21361 aaaaccaaaa acagtattca ttggaattaa atcgtctact atgttataga tcaaaaatgc
    21421 caccaaaata atcacactgt aaaaagattt ttgaaacatc aagcccaaaa aggactttaa
    21481 ggtattcatg agcatataat caaatactgg aacaaaagaa gcgagtaatg aaaaaggaat
    21541 cacaagtaat aaacacaaca ccaacatttg aaagataaaa cgaatcatgc caatcactac
    21601 aagtggtaat ccaatactta gattaagcaa tggcaccata gaaccaacga ctgctttata
    21661 aacagcttta gttggttgaa tatagacacg ataagccttc tttttccctc tatcttctcc
    21721 tgcagcagtg gtcacttttg tctcaatatc agataattct tcacttgacg cttacttggc
    21781 tagaaattct tgtggttcaa tctctgcttg atacaattct tctaaatttg ttgtcccata
    21841 atttaacaat atatacggat caacaacagc cgctttataa taaagttggc gcactttttg
    21901 aatggcttcc ttttgtgtcg ttggcactaa aacaccattg acatcttttg tcgccaattc
    21961 atctagacta tttgtagcag aaaaaataaa gccttctacc tccacggaca aatcatttaa
    22021 ccctttggta aaagcttctc ctttactagg tacgttacta ccatagccaa accaaaccat
    22081 tgaaaaaatg acaacgaaga gaaatcgaat aaacaccatt tttgcgtaat gtttccctct
    22141 aaatatacga agagtaaata gatataacac atacaagacg acaatccccg caccaatagg
    22201 atcgtatatt tttgaataaa tagtatccga aaaagtgaaa aactggtgaa ttaactcgtt
    22261 cattgcagct ccttcataga gcttctcaat gacaaaatca aggccttgcc aaatcaattt
    22321 acttaaacta aagaacatat tcgtcatcat ttttagaaaa tctgtgccat ttgccccaaa
    22381 taacattttg cctaatgaaa attcactatc agataaataa gaagaaaagg tatcaatatg
    22441 aaatttccca atctcataga tcgattgatc cacctgcttt tctgccgcat acaccaatcc
    22501 accaacaaaa agcagtccga atccaatcgt taaaaaaaac aaaacgcacc atttcttttc
    22561 cttatgcttt atataagcca ttgtttcacc tcatttctat tgcatgatta acgtatcctg
    22621 ttcttctact tgagagtgac ttgttttttc cgttgtttgt aatgcagcgg tcatttcttc
    22681 aaacaaactg tgtacattga gttttcctac acgtccatag ggatctaaca tccaacactg
    22741 tcctttaatc atgtggctca tttcagctaa gttcgcttca tttacttcca aacgtaaatg
    22801 attcaaaatc ttttctcgct cactgtcttc atcaaaagca aagacgacac caaaattccc
    22861 tttttcttta tctgaaccta agtcaccaat aaattgtgta tctaacacta attgattcat
    22921 ctgggaacgc cccacacgtg ccattgctgc aataatacta cgtcctgcgt tcgaattatt
    22981 aaatacccat gcttctgtaa aataaatcgc tgttttctta ctactatctc gttttccaaa
    23041 catttcacaa aaacgaccta aactaatcat caaacacaaa gactttcgat ccgcatctgt
    23101 atatagttct ggtcggacat tgtcatttgg taatttcaaa tcttggatct ctaaaatcgt
    23161 tgttttggca ttaaagtcta atcccgggtt ttctccataa gaaaatccta aacgtaaaat
    23221 cgaatcttct accgtcaagc gtaaaaactc accatattct cgaacctctt tttgttccat
    23281 ttgttctaaa tagtcgacca catgcatcaa gccaacttgt tgtccggctt ctttttgaac
    23341 taaaacttct tggattccct ttaataccgc cccttttaaa aggtgattgg tacctaacgg
    23401 acttaactca tcaatcatat cctgggctac ttgtttcgca tctactcggg ataaacaaac
    23461 aattggatct aatacaccat aattacgggg atttgtagca tctaacgtga cataactcat
    23521 tttttgcaaa tgttctacaa acaaagggta atgtttctga taatacgggt cttgaatgag
    23581 tttcgtaaac catttgcgct tttctccttt gggatccaca aataaacttt gtacattcat
    23641 aaacgaacta tacaaaaaga gcaagccaac taaaaaggtc ttccctttac cggtttttcc
    23701 agttactgct acatgaggcg catcaaacaa cgcacctttg attccttccg caatggctag
    23761 aagattcaaa aagacaaaac gatttgacgc ataaattaat tcttctaatg gtgttttttc
    23821 tcctcgagaa ccaccatccc ctaatgtatc ttgccgacca atataccagc cggattccat
    23881 acctaattct gatactgctg aaaacaacca ttcgccaact gcttctacag ttgttcggtg
    23941 cttccaatgt aactgccgtc ccaatggttg ccctaataaa catttataga acaattctcg
    24001 ttgatcattt tttgcacggt ggatatggat aatcgtatga agttgttgaa taaccgttgc
    24061 actattttga cgaacttctt caaccgtttg accgtataca ataaaacatg cgatccaatc
    24121 gacgacaggt tgcccattat ctactcgttg ctttaaatgt tttactaatc ctcgaacagt
    24181 taataagcgt tcactaggtt cttcatcatt ttgaaccaat tccttatgct ctgttttgaa
    24241 ccgttccgat agccaattca gttttaaacc aatacctccc tgtcctttca agcgtggata
    24301 gtgaattttc attcgcaatt ctgctgggaa agaaagatcc tgagcaaatt gaaatagatc
    24361 acaatttctc atattttcag gtgtttcccc aataggcaac aatgctaaat aactactccc
    24421 taactcatct tctaattgaa gaaggccttt atgttccttc ggtatacgta catacgttcc
    24481 ttgattgtct ttcagtactt cccaattatt ttgttcttct actttgtgag ccattcctcg
    24541 aatatattgc agacgattga gatacaacag ctcttttttt actaagggac gaatagaaaa
    24601 gctataaagt aattgtgtca cttcttttac ataaggatca ctttcagaaa acaaagtttc
    24661 caaatcatct acttctaatc caaataagcg tgctaaactt cctgctaaat ctaaccagat
    24721 tagatttatt acatcatgaa aactctccac cgttgctttt tctttgactt tgattcctaa
    24781 aataaatgaa ggacgataga cttgaccttc tcgttccaac aatgtcactg tttcttttgc
    24841 ataatacgca ccaattgctt gactatcggg agaaaatccc tttcctaatg tgtcaaactt
    24901 cgtccgtaaa ttcattgttc gtggatacat caccaactcc acatcttcat aatctgctaa
    24961 aagcaacagt aaacgagcca tcatttcttt tatttcctgt gtcttttttg gtgtgttttt
    25021 tgaaattgtt cgtggaaaaa catgatagta ggcccagata caatcctctc catttaacaa
    25081 acaatttttc ttgaatgctt ttactggttc ttttacaagc accaatgaat ttcacctccc
    25141 aataaaaaag gaacaaccag ttgattgtcc ctttttctaa tcctctaaat aaacatactt
    25201 attcacaaaa agtaattctt ccaatgcatt gtttgatacc ttgtcccagt tataatacac
    25261 acaatcacca ttcatcatac gaatcatata acaaaaccaa tcccataaat aaaaatgcac
    25321 tttttttcca tcaggtttta gttttgccag tgctaacaca cataaatagg ggagtcctat
    25381 ataaaaaaca actcctgctg gtggaaaaaa agaaatgacc caaccaataa atgaacgtaa
    25441 aaataaatat tcaaagatta cgaccaacaa aaaagttgct gcattgacta atgcaactgg
    25501 aaatggaaga cgccaattgc ttgtaatctg ttgtacgcga taaggttccg cataaacaat
    25561 cgaataatca taaggttccc aatccacttc actatcctcc taatccataa ataatttttc
    25621 aatgatttta ccaaacgcat caaatacacg tgttggatca tttaagaaga aataaactgc
    25681 ggcacctgct gcgatagata ttaatgcatt tcctactttt gatttcataa aatttcgcaa
    25741 tcccagataa acaaccacca ttattaaaaa atagccacct tgcgttaata taaaatctac
    25801 aattcccttc agtgtcattt ccgttcttct cctttcctat ccaaccaatt atgtgttaat
    25861 ttttcaacat aatactgatt tgtttttttc gtaatgacaa tcgtcatttg ttctttttgt
    25921 aaaagtgacg tatcaccatc tcgaaagacg accgttgctt ttacaataaa aggttttttc
    25981 gtttctttat aacgcaatac tttcatctct acttgatcaa ctttagctgt ttgattgagt
    26041 ccttcaggtt ctttcatcat gtatgacata tcttttgcat tgtttttcgc atacttatct
    26101 aagaaatctt ccacaaatcc ttcaacatct ttcgcttccg acgcatcaac cgtttcgtat
    26161 aatgtgtcat cataagtaat cattcgttgt ttttctgtat tctttggtag tgccgtaaaa
    26221 taaggataag caataatacg acagcccttg tttgaaatag aaaagggaag attgagtact
    26281 tgtgtgattg tcacacttgt ttctttctta ctctctggat tcatcgagcg aatatcataa
    26341 gttactttat aactagcagt tggaatggtt tcaatttctt ttaatccaat aaacgaagca
    26401 gcagttaatt ttcgaacacc tgaaacactt cctggttctt gaataaagtt ttgtgcataa
    26461 aactcttttt ttaatgtttc ttgacgttgt tgttcttgtt catgattatc gaatgtattc
    26521 atatacaaag caacaaaacg attcataaag gattcaattt caggtgtgta cgttaattct
    26581 gaccgacttt gtacttcttt cttttgtaat tgttggattt catctttcaa aaacgacact
    26641 tgaaccttcg ttttcatgga ttgaaaaaat gccaagcccc ctgaaaaaca aagaaataaa
    26701 accaaacacc aaatccattt cactgctttt tttgaatgga ttttcttttg cttcggtact
    26761 ttctctgtat aaactttttc tttccgccgt agttgtcgtt ttttcataag ctactccttc
    26821 tagtatgttt ttactagtac gtacgattga caacgataag cttgtttttc tgaaaaatag
    26881 tccattcaat taccctcatt ttctattcct tttctctttc ttttatatcc aacaaatcca
    26941 gcaatacttg tcaacactcc tcctagaaca gaaagtgcaa catgtatttc ttcaccagtc
    27001 tttggtaaga cttttgtttt tccatctgct gttttgattt caatattgcc acttggaagt
    27061 ttctttacag gaatcgacaa atcctttacc aaattccctt cactatcttg gattaatgga
    27121 ataccatctt ttacaccaac aattgtttga tcacctgcta cttttaatgg ggtggttggt
    27181 gttggaatat gggtcaattc ctctacatta ctagtgacaa tcggtacact cattccttga
    27241 gaagtattcg tcgtaatttc accgcttggg gttaccgata ctgtgacttc ttttgctgga
    27301 acaataggtt tattttcttt tggaattgct tctgattttt caacaggttg tttcggttct
    27361 tctttttgtt cttcactggt agacgacatc gttggctgtt ccgtacttga cgaatcagta
    27421 ttcttttcag aagaactggt tgttcctgat tgttccggag ttgtgactat acttgaatcc
    27481 gttgttgttg aactatgcac accttcttct tcgatcgaat cagtcggtaa agttgattca
    27541 ggaaactctg gttctggtgt cactggctct ttttcaggtt tctctgactg caattgttca
    27601 ggttctgctg gtttttccgt tgttcctcca tttagctctg tctcaacatc tggtaatcct
    27661 tcccctggca atgtttctac aatttctgac ttaggtgttt ctacagtttc atctgcataa
    27721 accaatgaac tccctaattg aaacgaaaat aatgaaattc ctagtgttgt tacgactgct
    27781 aatgttgttt ttttcatgat tattcctcca attttttatg caattcgtgt tttgttcata
    27841 gacgccgcac taatattatc tgaacgataa aagaactccc gtccgttttc ttctaaccca
    27901 acatatggat tatttttgaa taattgaatc aatagttcac tggtgttgta ttttggatag
    27961 tttgcaaaaa aataatactg tgcttgtcgc ccatccgaaa attcaacaag taattcataa
    28021 cgataccgct tcaatccttt tcgttgtttt aaaggatctc tataccaact tgtccatcgt
    28081 tccattcgtg gatagagata gacacgatac acatagaaca atgccatacc acataccacc
    28141 aaaaataata atcgccacat aaaaattccc ccttttcttc tacctttctt gaatcatcga
    28201 acattcatac cctctataga gatttgaaaa atccatcatc aattgttcat ataaacgttg
    28261 ttgcaaatag cgattgtttc gaatacataa ttcttcatag ccatcaatca cttgatcttc
    28321 tttttcatag catcttgtag ctctatgacg ctcagcttgc aagacataac caaactctgc
    28381 accatatcgt tctactgtta ataactgttg actacgcaat aatgcaatat aacaatcaca
    28441 aaaatgttca accgacattt gatttttctc acgtttgtga aataggtatt ctttagaaag
    28501 cacattattc gttaaacaat ctgataaata gcgataatct ggcggtcggt tattttcatc
    28561 tgtgaatttt tcccataata aactgatttt tattcgttca gcggctagat agtcttgttc
    28621 gcgtggataa aattcatcaa tcgcacaaag ttttttatca cctgaataaa caaatccata
    28681 taatgcgaaa cgaactcttc cttttcaatt ggctctccta aaaattccag tgacatacca
    28741 tcttctcctt cctaaaaaaa ataaaaaagc agaaaccgat ttggcttcta cttttctttc
    28801 cttttatagc tcttttttac ggaagaatcc gcaaatgaca ttttttcaaa aaatcaatcg
    28861 gcacaagttc acgaaaactt ggagcaattt tggatagaat cacttcccca tcttgtaaaa
    28921 tacaatcata aaaatcatca gttacttgat acttacgctt cttacaataa ttgataaaat
    28981 agtagcgatc attttctatt tccattcgtt gttctactaa gcgcatacga acatcatcat
    29041 agaaataagc cacaaatcgc ccttcaagtt catgtttttc aatgggatac tcttctggta
    29101 acaatctatt ttttcgtcgt ttatacattg ctggatacct tagaagaagt tcatctaaac
    29161 gtctgtcagt atatggtaac tgacgaatca acgattctaa tcgttcttta tacagataga
    29221 ataattggcg caagcaatag tgtaccgcct ctggattttc taatactgtt ggatcacgtg
    29281 accaatacgc accaacataa atcataattt ttttcattta gacaatcaca ccagcaatac
    29341 taatgaccga tccacaatag gtagaacaag tggcatagcg accaatttcc tctaattcta
    29401 tctcaatctc ttctaaagaa agatatgtct gttcttctgt tggctggcga ctcatttccc
    29461 aagtgacagt caccaatgaa atttcttcca taagaggttt ttcgctgcta agtgctgcca
    29521 cacagttttc atatatcttc attttatcgc agcctttttt aaccgctaaa atcgcaggta
    29581 ttggcaatga aaatcgataa aagcgaatga attctagcct tcctttcctt cggctaaatt
    29641 ccaactcttc gagttcttgt tcgtatccct tacgaacttc taataagcgt gcaatttctt
    29701 gccagttctc tttttcctga taacgtccag cttttaccgc ttgttcaata taaggaactc
    29761 gaaaacgaaa ataagacaaa tcaaccatct tttcatttaa tgcttcgatt gcagccttta
    29821 aatccaacag gcgcagccat tctgttgtcg tatatgcatt catgcaattt tccctcctga
    29881 cgttcccatc cattctagat agttttgttg ctcgtcattt agttcggcat tatcaatccc
    29941 ttcttgtaca aagtctcttc ctaaaatacg atctgcttct tgtaacaact ttaatgtcgg
    30001 agctacttgt ttcaaaaacc agcgttctga acgatctaat gagaattttt ctggctttac
    30061 tgtaaaatcc aattcttcca tcgaacgaaa taattttgcc catcgtttat caacaatccg
    30121 tgcatcactt tccagtctat cccaaacaat aagttttgca ttaattaaac caacgccaat
    30181 ctctcctaaa cgtttcggtg aatcacctaa aataaatgct tctactgctt gtgttgcttt
    30241 ctcattggct aaccgtaact catatcgatt ataaatacca tatttcgtta atgcttctaa
    30301 ttctgaaatt ttttctcggt tcgcaatttc aaaacgtttc tcataaaaat taaaaaagag
    30361 aggactcttt cgcgatccaa aatacaaaga taatccttca cttcgaaaat agccatcatc
    30421 taaaaaacaa ccgccaatat tctggaatct cttaaagtcc atttctaata aacctgcttt
    30481 ttgtttttct agtaattcaa agagatcgaa atgttcttcc gtttccaatc cccaaagttc
    30541 atctaacgca atatcgaatc ggctacattg cacacgtgta taaccagctt ccaactttcc
    30601 ttgatttttc caaatggaat atagccatgt tcgccaatct gtttgttgtt cacgcatgac
    30661 ttcctcatat tcccggcaac cttgtcctga aaattgcaca agtacatttt ctgttacagt
    30721 tcgttttgaa tgccagaaca cccagatatt cccacgaaca gaaagacagt caaaaagata
    30781 caagcccgtt ggacgtgttt caaattctgt cagatccatt cgtaatacac gttgaatcac
    30841 tgttttgtag tctgtcccaa aaaaggaaag acgcaaataa tcaatcattg ctcgaagatc
    30901 tattccgctt ttcatataca atcgaaagcg ttccttgatt cgttgttcaa aatcctctgg
    30961 gatttttctt ttcccttgtt ccatctttct aatgtaatct tttgagcagc ccatcaattg
    31021 cgcaaatctt gcttgtgata gcggcttttt atctccactt atattatgaa ttgcacttaa
    31081 cttctttctg tagcttttta gctcaatcgg tgtcattttc tcgctccttt tataaaataa
    31141 caaaatcgat tttttttaac cctttagaaa caccgatata tcaactagtc cccctcgttt
    31201 tttgggaaaa gtagtacaac tgctgacctt agataatcac ttgatacaaa agggtttata
    31261 aaactttttt ctatgtgtta tgttatttct gccccccata ttatatatcg gggggcttta
    31321 cacaaagagg ccgtgcgcaa gcgcacgacc tctttgtgag ctgcacacgc tgctagcgag
    31381 tgcgcattat aggcccatgc ttcgcagcct taatgcgcac cgccaggcag agtgcggcta
    31441 ccagactacg tctagagccc tcccgataga taataactac aaaattaaat gatctaattt
    31501 tgttatttca ctatattttt caggagaaaa aacgcgataa attgacaaag ttaaatcctc
    31561 ttctaaatct actcgataat gatacaatcg agtcaatcgt tctatatctt ttttcgttag
    31621 caatacttga ttaataactt ttcctgtaaa aacacgttct ttgcgcaaaa agcggtaatc
    31681 agttacttgt tcaatacgat tcaaccaatc ataaaacgtt ctggaagaaa gagaaggatt
    31741 aatcattcgt attgctgtag ctactctata ataacaactc tctgccattt aacttcacct
    31801 ccttagttga ttacaaaata tgcgcatcag aaaaacttgt tccttttgga tcttttgcta
    31861 aatacatttg gcgctctagt tgttcttgta acaactgatt atcatctccc atcgtttgat
    31921 cttgactatc ctcttttact gtaaaatcat agacaatcat ttcagtaaat ttctcaaatt
    31981 ctttgataaa gtgataatct ttgtaaacaa atggcgcaaa aaactctaca ggtacatcaa
    32041 atcctggaaa agcatatcca cgaccaggtt gatctttgtt gtaaaatggc ttatttttaa
    32101 aatcttctcc aaaagtcatt aaataaccaa tgggagacaa tcgaccaaca gaaatacgga
    32161 atgttaaatt atcccgaaca ccacttggaa aatattctgc atctggtcgt tgcattgcta
    32221 aaataatgta catccctgct tgacgaccct ttaatactaa tggctgaatc aatttatcga
    32281 ctctatttct cgcttccata tccaacgaac cataaaaagc tgcccattca tcaaaaaaga
    32341 taaaatgcgg tggtaaccca taataagcat aatttttccc tggttcatat ttaggatctt
    32401 tcatggtttt catataggca taccgttgat tcatttcttt taatgcattt cgtaaacaaa
    32461 taatcatttc ttcatttatt ttgtaaaaca catgtccttt gaatacatcg acgtcaccta
    32521 atgctgctaa atctgccgct tttccatcgc aaatatctac tgtcccaaca cttaaacaag
    32581 cttgaattaa agaatacaat aaataggttt tcccaccacc gattgcacca gcaatcaaca
    32641 tatttggtga ttgatcatat acccaatcca aagttttcat taaatgaata cgtccatttt
    32701 ctgctataca ttgatcaata ggaatccgac cagaatctga aaggaataca taattgattc
    32761 gggctttttc tcgttcttca cgaattaaat cacgcaaaaa tacttcagat aacaaatgac
    32821 ccatttttaa aaatcgttcg tgaaaacgcc caccatctaa aggaaaagaa accactaatt
    32881 cttgtttctt ttgataaaaa taaacttttg gtaatctcat tttttccctt gtttgtttct
    32941 cactaacttg tttctttgta taaacaaacc gattgtcaat taacattcga acaagtaact
    33001 gacgccaata aacagaggca aaatatcctt cttttagtcg cgaccaatgc atcaacccta
    33061 aaattaaccc actaaccagc aacaaataca acacaatact tattccagga ataagataca
    33121 tttgccaatt cgaaaacgta cttaaacgtg gataaaatac tttccaacta aaccaaccta
    33181 acagaatcaa aaatggaaac aaaaagaaac cataatagca aaaccataaa taacgattga
    33241 aatagcgaat tcgccgacca cgatacttga aaaaatgagc tttcaattgt cacattcctc
    33301 ctttctgttt ttacttttcc tgtgctaaaa acttttgaca aaaagcaact aatacaggaa
    33361 tatcacattt agtaaaaaaa cataatcgaa aaagatttaa tcgattttta taagggtgtg
    33421 cacacatatt acatattcgt actatacgaa tccaaatcac ttcctgatga tcttgtttcc
    33481 actggtacgg taatgaaaaa cgaacaagat cacgtaaaaa catacactgc ccaataaccg
    33541 cacaaatata tgcatttgtt tgtacaaaaa tcgttggatt gtctccaaaa tactcaatca
    33601 attgttggat attttgataa caagcacaat ctctcaaagt atttgattgg ttttatctga
    33661 attcaaaatc tccccttcct tctatcttag ataaaaagaa taggaagact ccttcctatt
    33721 ctttcaaaaa aaccttattt tttctctttt tccttagaat caacacttgg ttgtttttga
    33781 tctaaacctt tttcttgtga ttgtttcata ttaggattat ttgttggagc ttctactttc
    33841 tctaatcctt tcgcataaat cactaaatct gaatattcac gattgccatc ttgtgctgga
    33901 atatatacca catgatattc tggatcaatt aatttcacag gatcacgtcg tttaaaacca
    33961 gtcaaatcta catctgctgg aaatttaact cgtcgtgcaa tctttggttc atctggattt
    34021 ccaaaaacta attgtgctcg ctgtgatcga atttctcccg tataatcgcc tgtttcatta
    34081 tcaaatacac gatcagactc ttctaatgcg ccaaagcgta cggctcctaa acaagtttca
    34141 tctaatgctt ctgtaatgtc ataattattt ggaaatttta atcccatctt acaaaacctc
    34201 cccaattttt acaccagtta aaaagacacc aacatcttga tagccagttg ttcgacgctc
    34261 tgtttgtccc atatcatttg tttcacgact attcactcgt tctttacgaa aaacaaaata
    34321 agcttcttca aatgaaatac gcacctcttt ttctggtaat cgtaatcttt tatcctcttc
    34381 agctgtgaga taaacaaaaa aagcaggctg ttcttctcgc gaacactctg cttgtaattg
    34441 aacatatcgc ccagacacac cattaatttc ctttggtgga ttaggttccc gtgaacccaa
    34501 taaaaatact tgacctaaaa actctttctt catacgcaat gctttttctg ccataaagtt
    34561 tttcctcctc ttaaaaacca aaataaattc taaatatttc tacattacaa tcaaacaagc
    34621 ggttaaaaat cctaaccgct tgttcctcat gactaatctt tggctttacg tactttataa
    34681 agtgttatac ctaaagcaat gactaatact actaatccaa gaaccataag tatactactt
    34741 gtttgttcac ctgtttttgg caacattggt acaacagtag ctggtttaac ccgttgttct
    34801 ggtttcactg gttgcggtgg ttttggcgct tccacaattt gaaccgtttg atctttgttt
    34861 gttagatcta cattgtgttt cgccacttct tcaaacgttt ctttctcatc ttccgttttc
    34921 gcttggagcc attccgcaaa actcaagcct tttcctgcaa gattgcgacc gtccactaag
    34981 aattcaaata agaattccat catttcttta tcggccgcaa agactttttc cgcatgagtg
    35041 ccttcaaatg gtgtgccgtc tggtgttaag tagccttgaa caattaagcg atagatttga
    35101 ccaatcgcaa gaccgtctac tttgacccat tcaagcacag tttgatttgg caaggccaag
    35161 atctcttttc cgccattttt attcgtcgct ttcgtcgtaa tggttggatt actgattttg
    35221 atggtttggt cattgtcggt aatatctgcg tgagaagcca ataatacgcc ttctctaaac
    35281 agatcttcaa agaccacgac ttctttgcct cgcaacgcac gtgcgtctag aataaagtct
    35341 agattgactg taccatccgt tgtttctgcc acaaacgtta aggtacttgt gacttctttt
    35401 ccatctacta gcactggttt ttccgttact ttgtccatta gaacaccgtt gactgtgtat
    35461 gtttttccaa cgaccaaatc gtggtatttc acagcgtctg taatggtgac tttcgttaat
    35521 ggattaacct ctttcaagcc agtgggttta tgtgtagccg ttgtacgtac acttgggtta
    35581 gttactcgta ccgtttgccc tttgtcgttg atgtctttat ggtttgctag ttcttcatca
    35641 tttctaaaaa gactttcaaa cacgacgatt tcacgaccat ttatacctgt caaatcaaag
    35701 gtaaatggta cgatcaccgt ttcattttct gctttggcaa taaagccaac actcgtttct
    35761 accgtatttc catgcacaag caagggttca ccggttgctt tatccattaa gatccctttg
    35821 accaagtatg cttttcctgg aagaatctcg gtaatttcaa cggtatcgtt taaggtaaac
    35881 aatcctgttg ggtctgcgac tgtcaatccg tcttcaaaga cagccgtggt atgaacggtt
    35941 ggattattca ctttcacact ttgggcttca tcgttgatat ccgcatgtgc tgcaacttca
    36001 atgccatcac ggaaaagttt ttcaaaaaca acgatcgttt gacctttcag aacactagca
    36061 ttaaccacaa attcaaggtc ttttgtgcca ttgactttgt ctgcaataaa ggccaaggta
    36121 cttgtgattt ctttgccatc ttgtaaaatt ggcgcattcg ttgccttgtt catcaatact
    36181 cctgaaatgg tgtattcttt tccgacaaac aagttggtat aagaaacact gtctttaatg
    36241 acgatcgttt ctaatggatc aaccactttt tcaccatcgg ctttatttga cgcttgtgtt
    36301 tctagttttg gtggaatcaa gtaattacgt acagaaacca ctaacgtttc cccatcatct
    36361 ggcgcatttt gtttgaatgc aaccgtgaat gcttgtttat ctgtatttgg ttggaaactt
    36421 tctaatgggg cattttccaa gaagtaatag tcatcggcaa ctagaccttt cactaaaatt
    36481 tccccgtttt gatcagtggt atattcacca attgcttgat ttttaccgtt atacaaggta
    36541 aagttcacac ctgcgagcgg cgttttcttc ttgttccatt cttcatactt gaataatttt
    36601 acacttttcc gtgcttgacg gttcgcaaaa tggatcactt tgatcggttc tgtatcattg
    36661 gtaatcgaga acactaatgg gttttgattc aaaacgtaat ttacgggggc tttgatttct
    36721 tccaaacgat agcgatcttt tccataagta agtgtaccgt tagttaggaa aaagcctttt
    36781 tcattggttt taaagatatc cgttgtttct gtatcatttg gaatctccat tgtgacataa
    36841 cgattggcta aagtatcaaa aatcttgaat tctgtattag caagtggaat cacttttcct
    36901 gtttcttgat ccactttcac cactttaaga cgttgttcaa ttactttatc ttctaaaaca
    36961 taatggaaag tttgcccatt ttcagaaatt gtgacttcaa gtggttcaaa tagtttatac
    37021 ccttcttttc ctttggtttc agaaagaatg tacgtatcaa agacaacggt atttttacca
    37081 aaagtagcat aaccatcatt gtctgtcaca acggttttca ccactttgcc agttgttttt
    37141 gacgtcaaag tgatttcaat gccagctaat tttggtttgt tatctggatt cgttgaatcg
    37201 actaaatctt tattagcaac tttcactaaa tcaatggttc ctttgatcac ttgatctttt
    37261 gcggtcgcat tgacagtttt tccaggttca acaacaattt caattgcttc atcagaaagc
    37321 acataacctt ttggcgcttt gatttctttt aaaacatatt tgccaggatc aagatcttta
    37381 atttctgcct gtactttgcc gttaattttt ttcaaggtaa tttctttaat ctttttccca
    37441 tctgcttgat acaaaccata gaccgcattt tctaaagaag ctgcaccttg tgctttcaca
    37501 ccagtttccg catcttcttt aaacacacga atgtttcctt gttttagaat ttgtaaatta
    37561 ataacagacg cattaggttc tgttggatgt aacacaccaa ttgtttgagc tcctggacga
    37621 cgataggcta atggcgcacc ttgaacttta attttattca attgaatttt tgctttatcc
    37681 ggtgcctctt ttgtgactgt aatccatact tcattgccgt gaatagatac attgacacct
    37741 tttggttttt gaatgtcttt cacatatttc aaaaaatcat ttttattctt tactttcaac
    37801 gtttcgccaa tttttaccgt atgtgtttga ttattaaaag ttgctttttc accaaagtta
    37861 ttaatcaaac gttgaatttc tgcttttcga cgatcataat caacacgtat atttttgatt
    37921 gggatttttg tgcccaaagc ttcccaaatc ataaattgtg ccgcaatgta ttgttcatcg
    37981 gatttgtctt tatttgtgac atatcctaaa taagagatca agcttgtttt tttccgtaca
    38041 tttgaatttt tcaaatagtt tttcaaagca gtagctgtat aaacttgacc ttctgcggct
    38101 gagacaccag gctcaataca aaacgccact tgtccattaa tctcaaaacg aaccatataa
    38161 tttaaagtga agtttagatt gttcggacta gaagtaacac caatattttc gccccaatca
    38221 attttccgac cacctaaaac agctgcattg gttgcacggc gaacacgaac cgaacgattg
    38281 gttggtactg ttactaacag tgtaggtgta cctgtttttg gaatgttctg ctcttttttc
    38341 ttttgatttt caatactagc cgtagattct ttgtttggtt tcgttggttg attttgacta
    38401 gctgcggttg aagagattgt tttttcaacg ttttcctcat tttttccttc tttgtcagca
    38461 gtagccgctg gttgttccac tgtttcttct attcgtttct tttcttccgc ttgtttctca
    38521 gaagactctg gctgcacaga aggcgttgct tcggcagctt tttctccttc tagagtggac
    38581 gtttctgaag caggggttgt aattgaggca gtttcttcaa ctggttgtga agtaccagga
    38641 ctattccctg ggtgttgtgt ttccccaatc gtctgatcga gagtcgtttt ggaattgacc
    38701 gttggcgctt ctgtcacagg ggcctgttca acagtggctt caccagctgg gaccccggct
    38761 tctgctggtt ggacttctgt cacttcagaa gcgacttggg caatggcttc catcgtaggt
    38821 tgtatagccg tcgtttcttc tgcatgtgct tgagcagttc ccaccaagaa acagaattga
    38881 gaaaaagcca ccaatgcgag tgctttcaac caattcattt tcgtttttgc atacacaaga
    38941 attcctcctt ttcctgagaa ttttatataa taaaacaaaa cgccgttacc aaaagtgata
    39001 acgacgtgaa ctgtctcttc tatttttatc tggcgctctt atctgaacac atttcatcaa
    39061 tgattttacc ctcccactat aattacagaa caaaaaaaga acctgcttcg tggaaatcaa
    39121 ctgtccattt cccaattgga ataccagctt ttttggcaac ttcaccatca ccaaatctca
    39181 tgccatacca attactacct tcatccttaa tttctttcca accatatgac atagcttcat
    39241 ctaatgaatc aaaaatcatg acactattgc caattgttac aggatctggc ttaagatctt
    39301 ctggaagaga aatatcaatc ataccataat gatccgattc ctcagtatta ttgtcattac
    39361 tagctactgg tttggttgtt ctactggctt attttgatac aacaagtact cttattcttc
    39421 ttttacttct ccgttttcaa tttcccattc aaaccactcc gcaaagtctt gcttaaaacc
    39481 atctactcga tacctatttt gtaaataggc atcttctgac gtcgtaggat ctaaataggt
    39541 aggtttattc tctggacgag catagacacc tacccatgtt tcgtaatctc cttcaaaata
    39601 actatctacc aaatagcctt tttttctaag aatctcccga acttgatttt taattattga
    39661 tacttgttca aaaccatcac tcattctatc acctcaaata actctagatt ctcataaata
    39721 ttcccgacaa tttcaatcct atcaatgatc tctaacaaat cgctacttat gcttccccat
    39781 tcgtataaga atttcccttc cgcaaaataa attttccata aacttcttca tgatcgtccc
    39841 aaccaatatc actctcgaaa aattccacgt tgttcttatc ttttagctca gtaaatgcca
    39901 taagttcaac atgttttcca acctcgaaac aatcacacca cccatcaacc gttacacgtg
    39961 tgccttcaat acctaagaaa ctttgtcctc gtgtattaaa cactaaaact ttccgcattt
    40021 tttgctcatt aattaatcac gcgcgaaatc taggaatcac aacttattcg cttcttcttt
    40081 ataaataaaa aaactccaat aatcggaaat tactatcttt tcctcattcc ttttttaaat
    40141 cttcatactt cttcttatct ttgtcctaac ctaataacac aaattttgaa gaaaaactca
    40201 gtaaaacctg attctttttt tatcttcaca acaaccaact ttttcttcag atccttttac
    40261 tagaacttgt atacaaaaat tgttgaatgc tgatataatt tgcggctact tgaaaaaacg
    40321 atagatgtaa aaagataaat agaatcattt tttattctat atcagtctat gattcattgc
    40381 ttatcaatca cccaacccat tcgatgccgt tttttttaga gaaatttaaa aaagaccgta
    40441 cgaatctcgc attatccgat tacttttcca gaaaagatcc ccaattctgt ataaataacc
    40501 ctatcttctt gttggtttca ttttctcata taagaattca gtcaatctac ccactatgac
    40561 cattactacg tccaacacaa ctgacatatt aaccacgtaa gtattccctc acagatctcc
    40621 gaatctccat ggtatggatt cccatcctga cgctgcagag gacaacatat ttcatgtggc
    40681 tctgtaccct tttgatttgg aaacactaca aatcaatact catctataac ttatcaagcg
    40741 aactttcgct aggcttctag tgattactaa attgttggat aacatacata gcccatttta
    40801 tctagctgtt attcataaca gttagttctt gtattacttc ttccgcttgt gttgccattg
    40861 agcttgtcaa aaagttactt agaaaaaagc tgccagtaaa gcaactttca acaaaccctt
    40921 tttgtttctt atcatatcaa gaaacctcct tttataaatt ttttctataa taaaaaacgt
    40981 cgataactta ataagtatcg acgtaaacta tttttatatc ccgtaaatca aaaattctaa
    41041 agaaagattt cctatataag catattggat aattcgatta gtattgggta tatctctacc
    41101 attctcatac ctatctatgg accattttga aattgaagga gaaaaaagct ttccaaactc
    41161 ctccctttct agataataat ctttcctaat tttcctcatc cttaatccca tactaaaaga
    41221 atttatcttt ttaaaatcgc taactctttc atcttttgga agtatattct tataatcttc
    41281 tccgtacata aggtaaggaa cagtgacctt accaagatag gcaatattca ttagtttttc
    41341 aatatctgga atattaatac ctttttccca tctacttata acatttttgc ctgtatagat
    41401 ggtaaagttt ttaccaaatt tttcaagcgt ctcttcccgg ttctttcgga cttctcgtat
    41461 tctttttccc ataacaattt tatcgtcttt tgataaacta aatatctcac tatcacgatt
    41521 aatctccttc aaaatttctt tttcattact taatagaaaa atatcgattt ttttttgcat
    41581 ttcttttgac ggatttctct ttctatttaa cacataactg agtaatactt cactaattcc
    41641 tatattatca gctaactctt tgttaagtaa cttattcata tctctgtatg caattagttt
    41701 accgatgaga atctcaatct tatcttcctc atcttttatt agagtttcta tattcagaat
    41761 cttgcttaga gtattatcta cgtctttagg gatttttctt gacccttttt catatttaac
    41821 taaagtactt tgtgaaatac ctgctaaatc agctaacttt ttttgagata gttttttctc
    41881 ttttcttaga gatttaagaa cccttccact tgaattatca accatgaaaa aagcacctcc
    41941 tatgagatgc tttcatcata tactgacagc taaaaatctt caagaaaaat attccaattt
    42001 tgttaatttt agtatcgccg tgataaccaa atgacagttt aaaatctttt atacagataa
    42061 tcctcagtgt tgcatctact caaaaaggtt tatttaatag gtttttcgat tgattataag
    42121 ttatttcaca ctatcttgct catccatttt cagaacggcc atgaaggctt cttgcggaac
    42181 ttcgacggag ccgatttgtt tcatccgctt cttcccttct ttttgtttct ctaagagttt
    42241 acgtttacga gaaacatctc caccataaca tttagccaag acgtttttac gcaaggcttt
    42301 gatgtctgaa cgggcaacga ttttttgtcc aatagctgct tggattggca cctcaaattg
    42361 ttggcgtggg attagttttt tcagtttttc aacgattgct tttccacgtt cataggcaaa
    42421 gtctcggtga acgataaagc ttaatgcatc gactttttct ccattcagca agatgtccat
    42481 cttcactaac ttgctttttt gataaccaga catttcataa tccaatgagg catagccttt
    42541 cgtgcttgat ttcaatttgt cgaaaaagtc aaagacaatt tcagaaagcg gaatattata
    42601 gacgacattt actcggtaat catctaaata atccatcgta atgaattctc cccgttttcg
    42661 ttgagaaagt tccattactg caccgacaaa atcatttggg accatgatct gtgctttgac
    42721 gaatggttct tctacatcct gaatcgttac aggttcagga aaatctgccg ggttatctac
    42781 tgtagcagtc gtaccatccg ttttattaac atggtaaata acggatggtg cagtcgtgat
    42841 caattctaga ttgaattccc gttccaagcg ttcttggacg acatccatat gaagaagtcc
    42901 gaggaatcca cagcggaacc caaaacctaa tgcttgagag gtttctggtt cgaattgtaa
    42961 agcagcatca ttcaattgca gtttttctaa agcttcccgc aaatcgttgt aacgagaagt
    43021 atcaattgga taaagaccac aataaaccat cggattcatt tttcggtaac ctggtaaagc
    43081 ttcagcggca ggattgtctg ctaacgttac tgtatcccct actcgtgtat cttggacagt
    43141 tttgatactt gctgtgatat aaccgacatc accgaccatc aaaaagtctc tagcaactgc
    43201 ttttggcgag aagaccccga cctctgtaac atcaaatgtt ttgccattac tcatcagttt
    43261 gattttgtct ccgggtttga ccataccgtc cgtgatccgg acatttagaa caacaccgcg
    43321 gtaactatca taaatagagt caaagatcaa agcttttagc ggtgcatcta agtctccact
    43381 tggtgcagga acatattcca cgatctgctc gagaatatct tcaatcccaa tccctgattt
    43441 ggcactggct aatacagctt cactagcatc gattccgatt acgtcttcga tttcttgacg
    43501 gacacgttcg ggatctgctg cgggtaggtc gattttattg atgactggca ggatctccaa
    43561 atcattgtct aacgctaaat aaacattggc caatgtttgt gcttcgattc cttgtgctgc
    43621 atcgaccact aaaacggcac cctcacaggc agcaaggctt cgagagactt cataggtgaa
    43681 gtcgacgtgc cctggggtgt caatcaagtg aaagatatat gtttctccat ttttcgctgt
    43741 gtaattgagt tctacagcat ttaatttaat cgtgattcca cgttcacgtt ccaaatccat
    43801 cgagtctaac agctgatctt gcatttcgcg agacgtcaca gtgtgcgtca tttctaaaat
    43861 acgatcggcc aatgtagatt tcccatggtc gatatgagcg atgatcgaaa aattacgaat
    43921 ctgctcttgg cgttctttca ttttctttat atccatagcg tctcctcttt tcatataatc
    43981 agcactttcc attataccaa cgaaaagcag taatttaaag agtttttaat tagtcagcta
    44041 tagaagtttt ttttgtagaa ttttgctata ctgttatcaa gctaataaat ggagatgaaa
    44101 aaatggatca aaaagatttt agagaaaatc ttgaattaaa accggtcact caagaacata
    44161 tcgatcaatt caatgaattg ctttcctatg tgttccaagt gactgaagca gacatcgagg
    44221 aaagcgggtt tgagaataaa cgagctttta tccgttccaa aaaaccgatt ttggaagtat
    44281 cgaaagtgtt cggatggttc cacgaaaata aactgatctc tcaaatcgct atctatcctt
    44341 gtgaagtcaa tattcacggt gcacgttata aaatgggtgg tgtgactgga gttggaactt
    44401 atccagaata tgctaaccat ggattgatgc aagatctaat tatcgttgca ttggataata
    44461 tgcgcaagaa taagcaatgg atctcttatt tgtatcctta cagtatcccc tactatcggc
    44521 gtaaaggatg ggaaatcatg tctgataaac tttcctttaa aatcagagat acacagctac
    44581 ctaaacaaat cccagtaagt ggtatggttg agcgattacc agttgatcat ccagacgtat
    44641 tttccgttta tgacaaattt gcccaacaaa accatggtgc tttattccgc agtgattttc
    44701 attgggaaga gtattggcgt ttcgaaaatg aagatgagcg cacagccgct gtctactacg
    44761 atagcaacca tgaaccaaga ggtgttctgt tctactgggt agctgaagaa atatttcacg
    44821 taaaagaaat gttctatctt gatcaagaag ctcgaaatgg cttatggaac tttatttccg
    44881 cacatttttc catgatctac tgggtacatg gagatattta taaaaatgag cctttagcat
    44941 ttttgattga agatagtcag atcaaagagc agatcgaacc atattttatg gctcggatcg
    45001 ttgatgtaaa agaattcctt caacggtttc cgtttgttgg aacagctgat gcttttcatt
    45061 tcatcattga agatcctgtc gctccttgga ataatggtgt cttcgcttta acatgggatg
    45121 aacagggaca agtccgtgtc ttaaatgaac ctataggaaa atccgttcga ctggatatcc
    45181 aaacattgac ttgcttgatg atgaattatc gccgtgcttc ttatttggca agaatcgaac
    45241 ggttagaaac agatgaagaa acactgaagt cactagagcg tatcattcca aacatggaag
    45301 cttactttag cgattatttt tgataaaaag gatgatgttt agatgaaaat ttattttgcc
    45361 gcaccaatgt ttgctaaaag tgatttgtta tataaccaac agttagttaa agaaatcaga
    45421 gagctctctt ctgagctttc gatctatctt cctcaagaaa atgaagcaat caatgacaaa
    45481 actgcttatg cagacagtcg aatgattgct cttgctgaca cagaaaaagt gttggctagt
    45541 gatttaatga ttgctttact agatgggctg acgatcgatg ccggggtagc atcggaaatc
    45601 ggtgtggctt atgcgaaagg catcccagtg atcggcttat atactgatac tcgacagcaa
    45661 ggcggaaccc acccgaaaaa aatcgctgca ctacaagaaa cagctgaaaa tcaatttcac
    45721 tacctgaact tatatacaat aggtttgatc aaattgaacg gaaaagtggt ttcttcagaa
    45781 attgagttgc tttcagaagt aaaaagattt ttagatggag ggactttcag tgattaaaga
    45841 aatcaaaaag gtgcaaatag ctttacttgc ttttggtgta ttcgttgtct gctataattt
    45901 ttatgaattt atcacacaaa aatattcgac ttctcaagga atcacattta tcgtggaatc
    45961 tttattaggg attgcattga ttttcatgcc acaagtcatt ttgaaagttt tcaaacttaa
    46021 aataccagca gcaatcgttt tgttttactg gtttttcttg ttcatctctg tctttttagg
    46081 cacagggatg catttgatca gtatcatctc tttttgggac aaaatcttac atgcggtgag
    46141 tccaatggtc ctgacagctc ttggctatgg attgattggt tacttgatga aagatgctga
    46201 gatatcaaaa accagtcctt ggttgttcct cttattcggc tttgcgtttg ctggactttg
    46261 cggcgtgttt tgggagttct gggaattctt atgcgaccag ttcttaggca tgaatcttca
    46321 acgttttgct gcttctgatg gcacactgtt tgtcggacga gcagcattga tggatacgat
    46381 gggcgacttg ctgacaaata cgataggtgc tgccttaatg ggattgtttg catggtctca
    46441 aagtaaaaaa gatgagcgtt actttgaaag ttataaatta gaaaaagtga aaaataccta
    46501 ataaaagagg ttgtgacaga tgcgggcagc ttcaagaaat ttcggcttat ttttcgaaga
    46561 aactacttct ggaacactgt ttatttgaaa aaaggaggtc tgacactagt tgtgtcagac
    46621 cccttttttc ttttatagtc tcaatggaag attagacgat ttcttctagc tcttctgttt
    46681 tgaaatgaag ttgtccatca agtaaagtaa tcgttacttt tgatttaggc ataacatgtc
    46741 ctgcaacgat ttctttagct agtggtgttt ctacttcctt agtgataaat cgtttcaatg
    46801 gtcttgcacc atatgctggt tcataagcat tttcagcaat ccacgttttg gcttcatcac
    46861 tgattgtcag caggatttct tgatgttcca gacgttgtgc caattgcgcc accattttgt
    46921 caacgattcc tttcacgttg tctaggctca atggtgtaaa taaaatcgtg tcgtcgattc
    46981 ggttcaagaa ttctggtttg aagtttccac gtaatagcgt gttgacttgt tcagccactg
    47041 cttctggaat cgttccatca gcagtcacgc cttccagcag taactgtgaa ccgatattgc
    47101 tggtcatgat cagaaccgta tttttgaaat ctactactcg cccttttgaa tcagtcaagc
    47161 gtccgtcatc taggacttgt aacaagatat tgaagacatc gggatgcgct ttttcgattt
    47221 catccaacaa gacgattgta taaggatttc gtctgacagc ttccgttaat tgaccacctt
    47281 cttcgtaacc tacatagcct ggaggagctc cgactagacg agacacagca tgtttttcca
    47341 tatattcact catatcgatc cgtaccatat gatcttctga gtcaaacaag ttctcagcta
    47401 acgctttcgc taattcggtt tttccgacac cagttggtcc taggaaaagg aaagaaccta
    47461 gaggacgatt tgggtcttgc aatccagccc gtgaacgaat taccgcgtca ctgaccgcat
    47521 caactgcttc atcttgacca atcactcgtt tatgaagtgt ttcattcaat ttaattagtt
    47581 tttctcgttc accttctaca agtttcgtta cggggatacc cgttaatctg ccaacgactt
    47641 gagcaatctc attttcggta acggactctt gaaccatctt aatctcgctg tcttttgctt
    47701 tagcttctaa ttccttcaat tctttttcta attgaggtat cgtaccatga cgcaatacag
    47761 cagcgcgttc taaatcatag ttattttctg catcttctaa ttcgtgtttt gctttatcga
    47821 tttcagcacg ttttgctgaa acagaattga cttcttcttt ttctgtttcc cactgcatct
    47881 tcatcgcatt tgcttcttca cgaagttcag ctaattcttc ttgcaaattt ttcaagcgtt
    47941 ttttacttgc atcatctgat tcttttttca gtgcagcttc ttcgatttcc aactgcatca
    48001 aacgtctagt aacttgatct aattccgttg gcatagagtt catttctacc cgaatcgttg
    48061 cactggcttc atcgatcaaa tcgattgctt tgtccggtaa gaaccgatca gtaatataac
    48121 ggtcagataa agtagctgct gctactaatg cgttgtcatg gatgttaaca ccatggtgga
    48181 tctcaaaacg ttcttttaat ccacgcagaa tactgatcgt atcttccact gttggttctt
    48241 tgactaatac cttttgaaag cgacgttcca acgctttgtc tttttccata tattgacggt
    48301 actcatctaa agttgtggca ccgatcaaat gtaattcacc gcgagcaagc attggtttca
    48361 acagatttcc ggcatccata cttccttctg tttttcctgc ccctacgata ttgtggattt
    48421 catcgatgaa caagaggata cgtccatcac tttttttgac ttctttcaag actgctttta
    48481 gtctttcttc aaattcacca cggaattttg ctccagcgat caatgcaccc atatctaatg
    48541 aaaaaatcgt tttatctttt aaattttcag gcacatcttt gcgtacgata cgttgagcaa
    48601 gcccttcaac gattgccgtt ttccctacac cgggttctcc tatcagaaca ggattatttt
    48661 ttgtttttcg tgaaagaata cggatgacat cacggatttc ttcatcacga ccgatgattg
    48721 gatccatttt tccgcttttg acttgctgta ctaaatcaac gccgtatttt tctaatgctt
    48781 tgtattgttc ttcttggttt tgtgaggtca ctctttctcc tcctctcatc tcttcgatgt
    48841 ttttacgcaa ttctttttca gataatccgt ttttattcaa ataaacagtt aacggataat
    48901 tttttaattt catcaacgct aaaataacga cttccgttga aagaaactcg tcgccgaagc
    48961 tttcacgtat ttggtctgct tcattcaata atcgaaagaa attctggctg aggttttgtc
    49021 catattggac gtttccacca gaaacaactg gatactcatc cagtagacga tcaatttcat
    49081 gttcaaaaga ttcgacatcc aatccggcat ccgtatagaa atttcgacca aaatgattag
    49141 attgtaaaaa gattttccat acatgggcaa tgtcgatatc ttgatgtttt cgagtgaccg
    49201 caatctgttg agcttcagca atcgcttctt gaagcgtcgt agtcattttc tcaatattca
    49261 tacaggtata ccctcctaat taaaggtaag atcacttatt tctttgatct ttacaaaaac
    49321 tattatatcg ctttggtcaa ttttggtcaa aatatacaca tagttttttg actttttttc
    49381 tcgacttata taaatcttaa aaaaacaaaa ttgattgtat gtatataaaa aaagagccaa
    49441 acaaacgtaa aattatctta tccataacgt ttttctttga tttgataaaa agggtagatc
    49501 ttataaaaga cctacccttg attttcttta ttctcttttt ttacttctat tatttcttct
    49561 ttgatcactc ttcgccgttc agcaatcaca tacacaaatc catagagaaa tggcaagata
    49621 aaggaactga aacgatacag taaaagcgaa gaaactgcgt caactgttcc aacaactggt
    49681 ctgaataata acaaatagac aaattcaaag gaaccaatac cagcaggcgt aggaataacc
    49741 cctgaaagca ctactgcaaa gctgataaac gaaatggtca gtagaaaatc tattttagga
    49801 tggttttcaa tcagaatcaa ataaggaagt acataccaaa atacaagttt taacatattc
    49861 catagataaa tccgcaatag cgcagtcctg tcttggataa tggtttggac cgtttccctt
    49921 aaagagtaga tctgctgatt gcatgtatcc acccatttcc gcaaacgctc acttttaaat
    49981 aacttattcg ataagctgac aaaaaatatt tgaacattca agctgacgga catcgccaat
    50041 aaaaaggcaa caatcacgat cgtcaaaagg ataccagcga tgataaacca gatcattgat
    50101 ggaccattag aataaaaaag agagaattgg atgaccaagc cagctaatgc ataagtgatc
    50161 actgccagtt tgtacataat catatggagt gctgtcaccc ctgctccctg ggatagcttc
    50221 attccttttt tgttataaaa ataaatctcc gagatcagcg ttcctgtacc aaacgaaacg
    50281 attcggtaaa acgcaatata gctagaggtc aagaacccat ctttcgttgt aaaattcggc
    50341 gcgaaaggtt cagcaatttc tttgattgag cgcccttcag cgatttggta aactgtccct
    50401 aatataacag ccgctgccaa aacaacaaca ctggtagaca gcaattcggc aaagatatct
    50461 gcaaatgatt gattgattaa ataataaata atggcaaaaa tcacaatcag caaaagcaga
    50521 ttcagaatga ttttagtttt cgttccttta gacgacatct cctgctcctt aatggaaaaa
    50581 ataaatgaga atcaaatcaa caagtacacc tgcagcgaat cctatagtaa acttcttttt
    50641 ccgagtttta tgatggaaaa cttttcgaga gatcaatcct cccaaaccac cgcctaacag
    50701 gctgacaaat atcaaattat tctcaggaac acgccagccg ctagttctag cctgatgttt
    50761 atcatacccc atcagacaaa ataagtaaaa attcacaatg aaaaggtaaa accacaaagg
    50821 attgtgtaac aatacatcca ttactcttct tccaactttc tgttaactac tatttctaag
    50881 ctttttcttc tttctttggt gaataaactg ttaatccttt tgatacaaca gataattcaa
    50941 ctggaagatc atctgtcgtg tctccatccg ttcgagtgcc cacagatttt tcctgcgctt
    51001 ggattttcat gcgtttggct gtgaaataag taatgccggg gatcgtatag aatttgcctc
    51061 tcatgattct aggcaaataa aaaataaatc ggaaaatatc taaggaaggt acgatcgtta
    51121 catgaaattt tccatcatct agggtcgctg agtcgtcaaa atttgtaaaa ccgcccacgg
    51181 agttagacat cgtgactgtc aacagttggg attttccttt ccaatgctcc tcgtctgttt
    51241 ctaaatccaa atgatatttt ttcttcttca gcaataactt aaaaaacttc ttgataaaga
    51301 tccacgagcc gtaacgctgt ttttcttctt gactgatcca aactgctgta tctgctaaga
    51361 ttccgattgt cagtgtagag ataatgactt catcattgac ttgaccatag tctattttcc
    51421 gtacattgcc ttccaggatc acgtcagcag cttcttcttt tttgagggga atctcaagaa
    51481 cacgtgcaag gttgttgaca gttccacctg gaagtaatcc gacatggtat tgagataatg
    51541 ttttttggaa cgcttggacg atatgatgaa tcgtgccgtc tccacctata attactaaag
    51601 tatcagcttc tatggcttct gctttcttga ctaattccgc atcatcaatc gatgggccag
    51661 tttcagctag ttctacatat aattctggct gcttttcttt tacataatct tgaaaccagc
    51721 gtgctaattt ctcaccctca tctttccctg aacttttgtt ataaaaaact agcagctttt
    51781 ccattcttta cctcctattt actcttcaaa aaagagggcg ggacaaccaa ttccattgtc
    51841 ctgcccttta gccttagaca gatgacattc catcattggg acgaacgcct tgtcataagc
    51901 tgttcttttt cgattttaac tctttgtgtt caattctgca atttttacaa tcacgtctgt
    51961 tgctttttcc attacttgta aagaaacaaa ttcgaatcgt ccgtgcatat tttctcctcc
    52021 ggcaaataga tttggcgtcg gaatacccat gtaagagatt tttgaaccat ctgttcctcc
    52081 acgaactggt tcgatcactg gagagatacc aagctcgatc attgcttgtt tcgctaattc
    52141 cacgatgctc atatcttttt caatgatttc tttcatgttg taatattgat catacatatc
    52201 tactttgatt cgttcttgat caaatcgctg attcaactct tcttggatat gtgtgatttg
    52261 tgctttgcgt gcttcgaatt tttcacgatc atgatcgcga atgatataac tcatagaagc
    52321 ttcttcagga ttcccatcca atgccatcaa atggaagaaa ccttcgtatc cttccgtttt
    52381 ttctggaact tcatcggctg gaagctgatt atgaaaatcg attgctaact gtagagcatt
    52441 gatcattgta tcttttgccg tccctggatg tacatttttc ccttggatcg taatatttgc
    52501 ttgagcagca ctaaacgttt catactgcaa ctcacctaaa ggaccaccat cgactgtata
    52561 agcaaaatct acatcgaatt gctcaacatc gaatttatcc gctccgacac cgatttcttc
    52621 atcaggacca aaagccactt tgatggtacc gtgagggata gaaggattat tgatcaagat
    52681 ctccattgca gtcatgattt ccgcaatccc tgatttgtca tctgctccca gtaatgtact
    52741 gccatctgtt gtgatcaatg tgtggccttc ataatttttc aaatttggaa aatcttttgt
    52801 attcaatgta tagcgttctt ccgcatctag tacgatcgta gactcgccat catagttttc
    52861 aatgatttgt ggattgactc ctactgcatt aaaatctgct gtatccatgt gggaaataaa
    52921 tccaatggaa cgcacttcat gatcaacatt gcttggtaat gttcccataa cgaatccgtt
    52981 atcttcatta tagaaaacat cagctaagcc taactcttct aattcttttt tcaattcttg
    53041 cgcaaaagca acttgtgtct gagtcgatgg agtcgttttg cttgttgcat cggagcgtgt
    53101 ttctgttttg acatatcgta aaaaacgtgg caaaagattt tcgtacatag tattctctcc
    53161 ttttaattaa attgaaatgg gtttgtattt gtttcagaaa cgaaaaagtt aatatcccaa
    53221 ttttcttctt gtttccaaga ttcaaatttc tcgataaatc gttgcttgca taacgattca
    53281 atataatgac cgggatcaat tgcaatcaac ccagcgcttt gcatatcatg agccgtatga
    53341 taatagatat ctcccgtgat atagacatct gctctttggg cgattgcttg cggataaaat
    53401 ttttcaccgc ttccaccgca aatcgcaatg cgcttcacag aggattttgc attttttggc
    53461 tggactattc tcagtccatc tagttggaac gcttctttta cttgttctac aaatgcctct
    53521 atagaaattt cttgcggcaa ttcacctact cgtcctaacc caaacatttc gactggttca
    53581 tctatagcga aaagatcata agcaggttcc tcataaggat gagctgaccg catggcttga
    53641 atcacttgtt tttcgatagt ttccggcaaa ataacctcaa cttttgcctc ttgaacttgt
    53701 tctgtcttcc ctactttccc aatcgctggt tgtgcaccag cttccggagt aaatcgaccg
    53761 tgtccaatcg aggtaaaact tgtaccggta taatcacctt gtgtaccagc accagctgca
    53821 gctaatactt cacgcatttt ctgtgcatga tccacaggta cataaacggc cagtttttta
    53881 taatgaatct catgagtctt tactaaataa ctctccactt caataccgag aagttcacaa
    53941 aaccagtcat tcagtccatc ccaaataata tccatgttcg tgtgtgctgc atagacggca
    54001 atatcatgtt tcaacaaatc tgcatacatt ttttcttgtg gctgatcagt aaccagccgt
    54061 tttacaggac gaaagattgg aggatgttta gcaatcagca aatcgatttt tttcttgatt
    54121 gcttcttcga ccacttctgg acgaacgtct aatgtcatca ttactcgttg gattggctta
    54181 tccaatgttc cgatatgcag tccgactggg tctccttctt cagctagcca ctgaggacaa
    54241 tagctttcaa acttttggat gaaagtgcgt ccgctgattg tcatggcttt aaaacctcct
    54301 caatcatttg gatttcctgc tcgatttgtt tttgacgtgc ctcttgatta gctgcttgtt
    54361 tgagctgttc acggatagct tttctttgtt gaagctctct tgtccatttt gatttgaaga
    54421 tctcactttt ctcttcaagc agaaatggcc cgaacatcag ctccatttca ttgtaagtaa
    54481 ctggtttttg ttctttttcg gctacaatga tttcatatat ttttttattt tcttcaagta
    54541 ttttttctga ttggatttta tactgatttt cttgcagcca agatcgtaat gtacgctctc
    54601 cgatgtttgg ctgaaggatc aaacgttctt gtccgcttaa gcgttgattc aacttgccag
    54661 cttctaggat atctcggatc agtgaacctc ccatacccgc aatcgtgaca gctgtaatac
    54721 catcttgtgg ctggatagca tctagaccat ttgcaaggcg tacggtgata cggtcttcta
    54781 atccatcttt tttgacttgc ttacgtgctg attcataagg accttgaacg acttcaccag
    54841 caactgcata ttcgattttt cctcttaata tcaatgcaac gggtaagtaa gcgtgatctg
    54901 atccaatgtc tgctaaacga gcggattcag ggacaaagtc acccactgcg gctaagcgct
    54961 gagataaatc taaatggttc atagcttcac tccttctaga taattatagc attttccaaa
    55021 taaaataagg agactaggaa taaaaaaatt cccatatctc cttaaaaaat ataccttttc
    55081 gttctataaa acaacatttt cttatttttg aaaaaatgtt attggttatt tgttcaatga
    55141 aacatcaata atcgaatctc caggaacttg cggtgggata gacatcgtca tgatcggcat
    55201 ctcaactaat gtaaattgga ctttgtcacc gattttcaat tcatttatgt ccacgcttat
    55261 tttttcagca gtagcattta agatcactcc gtcattgctg aatgacgttc ccatattcgc
    55321 tggatcttct ttggccatga catcgacgag tttcaactga agcgtttctt cttctgcttc
    55381 tacttgagtg atactttcaa tcgttccgac aaatatgctt tgtctctccg ttttcgtact
    55441 gcttgttttt actgtttgac ccgcatcaat cgaatcaaca gaacctgtgt tgctatctgc
    55501 gctaccgcag cctgctaaaa gaaaaaatag accaactaca gatatactag aaaaaatagc
    55561 cctcataaaa aatcctccgt ttaagtttct gcattacttg ttgcggtgat tgtctccggt
    55621 catttctgtc catataatga ttcgctgacc tgcttttact actaggtcaa atgtcagttg
    55681 gacttgtcaa ctgttcaacc attgcgtcgg ttgcgaccag tcatttcgat ttcttttgtc
    55741 aaataacgta tgcgttccat tatccgtttc gcttttagcg gctcttcatc tccacgttga
    55801 gtgacggaca aatgctgttc caattcatcc attgtaaaat tcgatgagaa gaaggttggt
    55861 aactgttcct gcatccgata ttgaaggata acaccgaata cttcgtctcg tatccaacta
    55921 ctcatcgcat ctgcaccaat gtcatcgatc atcaaaatag gtgaacgttt cactgcatct
    55981 aacttttctg ccacttgatc ttttccgatt gcctgtttca tctcaacggc aaatgtcgga
    56041 aaatggacta gcgtcgtggt gaatccagca atcgctaatt ctctcgctgt tgctcctaat
    56101 aaatatgttt ttccaatacc aaaacttcct actagataca gtcctttatg ataccctttt
    56161 ggatcagcag tatatttctc tacaaaatct agggcttcta agctcgcata tcctcgtcca
    56221 tctgtacgtt caaagttttc aaaagaagcc gattgaatat cttttggcat atccattgct
    56281 tttactcggc ttctgatttc ttcttgtctt tgccgtgcta acaatgcttc cgttggtaca
    56341 taagtgacat ccacataatg aaaattcaac gtcagcttcg gctcatagcc gggagcgatc
    56401 atcgttggat cgtttttttg atatttacgc ttttcttgca cgaattcata caatttagcg
    56461 taactttttt caatatccgc ttgtgtcaat tcttcttggt gtgcgcttag aaaagcttga
    56521 acatccgcat catttaagac ttcagcgatc atttcagcat acttttcttg ataattgcgt
    56581 ttgctgatga tcctcttcaa ttctttgcct acgtcttcca ctagatatca ccctcctttt
    56641 ttgccaggta ttctttaaaa cggcggtcaa tctctgcttt tttctcgctg ctgatctgtt
    56701 tttcatcttt tggctggttg acccaatcag gaagcttttc ccgtcgaaca tttcgcttgc
    56761 cagtttgata atttgtttgc ttcttttgtt ttgattgttt tgcttgatta cttatttgcc
    56821 gaatgtgctg gatcgcttct tctgctgtgg cgattttctt ttgtgcccat tcatttgcca
    56881 ctgtatttac ataactggca tttaagctag cattattctt gatcactagt acataattca
    56941 gcaaaacatt gatcacgcta ctggaaagac ctgattgaga aacaagatct tgcagtaacc
    57001 agttttcttg tttagaaaca tatccgcctt tttctgactt gattgcttcc agatatttca
    57061 tcggtggaat gctctgtgct tcttttatca gctgaagcgc tgcgtttgtc aaatgttcgt
    57121 ttgacgaggg ttcattactg ttttcagaaa ccgcaactgt ttcttttgtt tgcttcaccg
    57181 gacgtctctg cattgccaaa atggcttttt gcagttcttt ttcagatact ttttgttcac
    57241 taaagtcata agattgactg atcagttcgc caagtgtcaa ttcatcgaaa ccgtaaagct
    57301 gatgatacat gtcgacttgt ttgatgattg gatcatcaag acttgcaata tgtttttttg
    57361 ccagccaatc attcaaaaac tgccaatcga atgtcgaatc tgcttcaagt aatgctactg
    57421 attcagattc ttcaaaagat ttattcagcg attcgatgtt ttcttgatta gcagcgtaca
    57481 ctgcttcatt gaagcgataa acatctaaaa atttttttgt gattttttga tatccctctg
    57541 ctgtatgcct tttaggttca aagaattggg taagcttctg gaatcgtcgt tcaccaactt
    57601 tttccagaag aagaaaagcc agaacagagt ctttgaaaaa tgctttagga atgagtggtt
    57661 ctaacagctc ataaataaaa cgaggtccca gatcactatc ttctttaaaa taaacatcca
    57721 gtaagccgat tccttctagc ttttttcttg catcataaaa ttgcgggata ccgcagccta
    57781 gactactaag cagatctgca tgcatccctt caggaccttt gccagattct tgagagattt
    57841 ctgataacag ggtgaaatag atactcaagg cttctccgcc gattagtggc tgataaagat
    57901 acagcaaggc gttcttgctg tcttctctca gcggagccgc ttttcttcct tggtaaatat
    57961 tttttggttg aagctctttc caagcatttt ccaaggaaat gcctcctttt tgtttcttaa
    58021 ttgttttctt tattattctc tttattattt tcttttgctt tatccacgat atcttgcaac
    58081 tcttttaaga aaacagacat atctttgaac tggcgataaa cacttgcaaa acgaatataa
    58141 gcgatttcgt ctaaatcaac taaatcttcc atcacatatt caccaattag attcgtcgat
    58201 acttcgtttt ctccgagact gcgtacgcgg ttttcgacat ggttgacgat ttgttccatt
    58261 tgttccatag ctacaggtct tttttctgct gaacggatga gtcctcttaa aattttatcg
    58321 cgattgaact cttcgcgttc cccgtttttc ttgattacta ataacggagc agcttcaatt
    58381 cgttcaaatg tagtgaatcg gaacgaacaa ttctcacatt cgcgacggcg acggatcgca
    58441 cgtccatcat ctgcttgacg gctgtcgatt actcgtgaat tattatgttg acatctggga
    58501 catctcattt tgtctcacct cttgcatcgc attttatata aaggatgtgt ctttctttac
    58561 aactagttgt attataacac gaaacaaatc acaaacgcga ctgtcctacc caaaaaacac
    58621 ggatataaga acaatttttt ctactttcat gcgtaattgt gtcccctgtc cttactaaat
    58681 ttcaattttc caatactgat caccttgatt actgagaaat aacttacaca aaagctgatt
    58741 tagtcatcta gcacaaaaaa cttgaagcag atgaacacct tctcatctgc ttcaagtcac
    58801 atctcgattt tttactattt tataacttct cttcgattcc tgtatagtgt ttcattcgct
    58861 gttcctcgat tttttgctca tcgggaatgt ggtcactttc tgggagcggt gttttactac
    58921 gatcaggtgt cggatttttt cgttcttgag tcaaatcttg ccgcttcgct tcttcttctg
    58981 cctgctggtc ttctatttca tcgattcttg cttggtactg cttttctttt tcttctgctg
    59041 tttctgattg cgtacgacct tcatcgatta gattttcttt attgagcatc tcgccgattt
    59101 tttcttttgc gttacctacg actttatcct tttgattttt taatgatccc atcgctatcc
    59161 ctcactttct atatactcag gatagcaaaa ttgacacaga tactcaaaga aagcgattag
    59221 caaaaagcca attttcgatt tgtcccacaa gtatttcttt tgttccattg ttgtcgaaca
    59281 aaatatccgc acgctgcttt ttttcttcga ttggaagttg actactaatt ctctgctgcg
    59341 cttgttctag cgtcagttga ttacgtttca tcaaacgctg aagctgagtt tctggcgtag
    59401 tataaacgac agctactgca tccatatagt ggtcataatg accttcgtag agcaatggga
    59461 tatctacaat tactaaagga tgattggaac ttagagaggc gatttgatct tttatcgctt
    59521 ttcggataaa cggatctaat agctgatcaa gtttttgccg tttttccttt gatggaaaaa
    59581 caatcatccc aagtttccct cgatctagtt gcccatcagg ctgcaatacc tcttggccaa
    59641 acactgatac aattttcctc agagcaagcg ttccaggctc aacagtttct ctggcaatca
    59701 catcgccatc gatcaaagga aatccatgag actgaaagac tttggctgcc gtacttttac
    59761 cggtagctat tccacccgtc aaacctaaaa caaatcctac tttgcgattt ttagcctttg
    59821 acaattcgga caatagtgcg tccccctttg tgccactttt gttttcacga tcggcgttcc
    59881 acaacgtata catggtttgc cagtttgctg atagacatgc agtgctactt gaaatccgcc
    59941 tgattctcct aatgcattca aataactgcg aatcgtggta cctccggctt ctattgcacg
    60001 atccaaaaca tcaatgatcg atagacgtaa ttgttctacc tctttggggc gcagtgtgtt
    60061 cgccggttgt tctggatgga tcttcgcttc ccataatgct tcatctacat aaatattacc
    60121 tagaccagtc actagacgtt ggtctagcag caatggcttg attgctttgt gggacttttt
    60181 cagtccattt gcgaaatctg ctaataagaa gctatctggc aaaggctcag gtcccaattt
    60241 catgattcct cggtaagttg cacttgctcc tttttcgacg attgtcatac gaccaaattt
    60301 tcgtacatcg ttgtagcgaa gttggcttcc atcctcaaaa aagaaaagta catgcgtatg
    60361 tttatcgatt ggtgtatttt ctttcgtaaa ttgatatttt ccttccattc gcaagtgtga
    60421 gatcagttca caatgatcga gatgaaaaat taaaaacttc cctctacgtc caatggattg
    60481 gatggtttcg ccaacaagag aagcctcaaa gatgggtgtc tctggttgct cgatgatctt
    60541 gggccacaag acctgaactt tttgaatcgt ttttcctact actaaccgtt ccaatccttt
    60601 acgaacggtt tctacttctg gtaattctgg cattttttct tttcaccttc attatattgc
    60661 tctgtcttaa acaatgttta ttttgcttcg taccacgttt ttccccaact gctgtcagtg
    60721 atcagtggta catgaagaga aacagcttgt tccataactt ccttcaccaa tttatctaat
    60781 gattcaagtt ctttttccgg tacctcgaag acaagttcat catgaacttg taacagcatc
    60841 gtagcttgaa gacctgtttc ttttaatcgt ttatccaatt cgatcatcgc gattttcaaa
    60901 atatcagcag cacttccttg gattggtgta ttgatagctg ttcgttccgc aaaagaacgg
    60961 atattgtaat ttcttgaatt gatgtctggc agatatcgac ggcggtgata cagcgtttcg
    61021 acgtagcctt ggtcttttgc ttcgcgtacg attctttcca tatattcttt gacacctggg
    61081 tatttttcaa agtacgtatc gatgtattgc tgtgctgctt ttcggctgat tcctagattt
    61141 tgtgaaagtc cgtaatcaga gatgccatac acgataccaa aattcactgc ttttgcctgc
    61201 ctacgcatat ttggtgtgac atcctctgcc ttttcgattc caaatacacg catcgctgtg
    61261 ctggcatgga tatcttgacc ttctaggaag gcagctttca aatgttcatc atttgagata
    61321 tgcgcaagta cgcgtaactc gatttgtgaa tagtcagaag aataaatcag ccagtctttt
    61381 tctctaggaa caaatgcctg acgtatcttt ctcccttcat ctaatcgaat cgggatgttc
    61441 tgcaaattag gatcaacaga gcttaatcgt cctgtttggg tcaatgtctg gacataacgg
    61501 gtatgcactt ttccatctga ttggatcact ttcagcagtc cctcgacata ggtagattga
    61561 atttttgcaa tttgacgata ggtgaggata tcctctacga ttggtgcttg ttcacgaagc
    61621 tgttccagta catctacggc tgtggaatat ccagtttttg tttttttgat aacgggtaat
    61681 cccatttttt caaataagat cactcctaat tgctttggtg aattcaaatt gaattcttcg
    61741 ccggcttctt cgtagatttt ttgttcgatc tctcttaagc gagcagagaa ctcgcccttc
    61801 atttcttgta agcgagtcgc atctactttg atcccgctta tttccatctc tgccaaaatg
    61861 atagacaatg gcagttccat tttccggaaa agatcttctt ggtttttttc tgccagttct
    61921 tggctcaatt ttggtgtcaa cgcattgatt gcagctactt ttcgcgctaa atgagcaaaa
    61981 aagagttcct cttcttctgg taaacctttt ttcgcccctt tgccgtatac agcttcatct
    62041 gattggatat cgttgtatcc gtaatgagca gctattcctt cgatatctgt gcttttttca
    62101 ttcgtatcga gaaggtatgc acctagcaag acatcaaaat cgattccttt cgtttttcca
    62161 gtatagcggt ttaaagcaac ataagttcgt ttcgcatcat atactttttt cagccgagtc
    62221 ggatcagtga tccaagaatg gaacgctcgg ttttcgaata cagatagatc gttcgtgaca
    62281 taaattttct tttctgtccc ccacgctact ccgacgattt cctctgtatg ataattgtcg
    62341 cccatcattt ccacgtacaa cgccatatcc gtagtaaaca tttcctcttt gaattcatga
    62401 acgacttcaa acaaaatatc atccattttt acttcttctt ctacgatatt caatttagaa
    62461 aggaactgat tgaaatccat ttctttataa aacggaacga gtttatcgag atttttccct
    62521 tcatacttca atgagtcgat agagacatcc acaggcgctg aagtattgat ggtcgccaat
    62581 tttttcgata agaaagcctg ctctttgtca tttatcagat tttctttcat tttgctttgc
    62641 ttcatttcat cgatatgttc ataaattcct tcgactgagc catattgttt caatagcttg
    62701 atagctgttt tttcaccgat tttagtcaca ccggggatat tgtcagaggc atctccggct
    62761 agtcccttca tgtcaataat ctgttttggc gtcaacccat catatttttc cgctacatgt
    62821 tctggtgtat agctttcgat atcgctgaca ccttttacag tgatatccac ttttacttct
    62881 ttactagcta attgagtcaa atcccgatca cctgaaagca cgacgacatc aaattgatct
    62941 ttgtctactt tttctgccaa agtaccgata atatcatctg cttcataatt gggcaattcg
    63001 taatactgta cccctagtcc tgtcaacaaa tcacgtatat atggcatttg ttctttgaat
    63061 tcgccaggtg ttttggatct tccacctttg tactccgcat acatttctgt ccgaaaagtc
    63121 gtttttcctg catcgaacgc aaccagaaca tgagtcggtt gctctttttg cataacattt
    63181 tcaaacatcg tattgaatgc atagattgca tttgtatgaa gaccgtttct atttttgaaa
    63241 cgttcaagag aattgtgaag cgcaaagaat gcgcgaaaag ccacactgtt cccatcaacg
    63301 agtaataatt tattttttgt catcttctta actccttact gtaaagttct tattcattct
    63361 aacaaagaat cctgcggaat gcgaaaagaa aaagcgggac cataccaaat aattcggtat
    63421 agccccaact gatgaatttt tttctttttt agttgttccg tccaaagatt ctcagaaacg
    63481 ccaagaacaa gttgataaag tccaaataca gcttcaatgc catgaataca gcaattccac
    63541 tatgtgctgt tccgtttgtc tggacataga tattacggat gctttggtta tcataagctg
    63601 taatccctgc aaagatgacg actaacagta gggagatgaa cagctcaact acgctacttc
    63661 tcaaaatgaa gatgttcaag actagtgcaa tgatcactcc gattaaagct gcctgtcctg
    63721 ctcttccaac cccgctaaga tctctttttg ttgttactcc gacaacagac atccccatga
    63781 acatcaaagt agctgtcaag aaagcttgcg ttactgttcc aatatcgtag tatgcaagag
    63841 taaccgctaa tattatgcca ttcaaaagag agtaggcaat aaatccaccg attgctaagc
    63901 tcggattctt ttgtgctttt acgcctagaa ccattactaa aatcagttca acgatccaca
    63961 gacccacaaa gcctagtgga aaattattga taaaagttgc taattgcaaa ggaaataccc
    64021 aaagagccaa gtaagaagtg actgcactaa gggcaagtcc catacctaaa aatccataaa
    64081 cttttgcata aaaacgattg atacctgaca ttgatgtact tggattattc attcaattca
    64141 ccttcacttt cgattgctat ttccaattca ggaacttgtg gcggttggac cataacgaca
    64201 gcatccaaca cacgatcttc gttcgtattc tccgcttcta cagaaatcgt caccacatcc
    64261 ttcatcttat ctacttttat gacctcaaac tgaaaagtca gtgtttcata atggaaaacc
    64321 ggttcaataa aattgacaga aaaattgaca acatgtgatc ctggtccagg aagatgcttt
    64381 gaaattgcac ttgtgatgat ccccatcagc atcactgatg gaacgattgg ctgttgatat
    64441 tctgtttttt gtgcaaagtc atgttggata tacaaaggat ttgcatcatt cgtcaatccc
    64501 aaatacagca aaagctggtt atcttcaata gattctgtta aggataacga gtcgccttcc
    64561 tcgatttcat ttattgtttt tcctagtttt ctcggcttac ctatgttcaa gatagaaacc
    64621 ctccagttta tttttaatca tacattattg taccaaaagt agcgtaaaag gcaagttctg
    64681 ctcccttgat ttaacagatt cctatagttt acagaggtcg tgaaaaagct gtcctgcatc
    64741 aaataataag aacagccaag aaaaaacagc ttctcatgtt tttgatttga ttgggcttat
    64801 taccgcagat gcaagctttt gaacaccgtt tatcataagt tgcaaaaaag ggggcttggc
    64861 aagatttttg ccactccccc tctttctatt tttataagga cactgcagta attgtattac
    64921 agtacatttt tcgtcgtgct gcttaaaagt ttttcatacg cttgttcaaa tttttgaaca
    64981 tctccagcac ccatgaagat tactactgca tcatgataat ctaacaatgg agatacatta
    65041 ttttctttga tgacttctcc accttttttg attttcgctc caaggtcttc aatcttaacg
    65101 tttccttgtt cttcccgagc cgaaccaaaa atatcgcata agtaaacttt atcagctaaa
    65161 tcaagtgctt ctgcaaattc atccatcaat gcaatcgtac gcgtaaacgt atggggttgg
    65221 aaaactgcaa ttatttcttt atctggatat ttttggcgtg cgccatcaat cgttgctttg
    65281 atctctgcag ggtgatgcgc ataatcatcg actacggtca tgtctgctac gatcttttca
    65341 ctgaatcgac gttttactcc tgggaaagtc agcatttctt ctgcaacttc tttcagatcc
    65401 agtttttcga aataagctac tgcaataaca cctaaagcat ttaagatatt gtgtttaccg
    65461 aatgctggta cagtgaagtg cccaacaaat tcatccccat gatagacatc aaaagcagaa
    65521 ccagaagttg tgcgttcgat gtttcgtgct tggatatcat cgttttctgt gacaccataa
    65581 taataaatcg gcacatttgc ttttaatttg cgtaaataag catcgtcacc atacgcaaaa
    65641 atagcttttt tcacttgtcc agccattgtt tggaaagctg taaatacatc gtcgatactt
    65701 gtataataat ccggatgatc aaaatcgata ttggtcatga ttgcatagtc tggtgaatag
    65761 gcaaggaaat gacggcgata ttcacaggcc tcaaatgaaa agaattccgc ttgcggatca
    65821 ccatgtcctg ttccatctcc aattagataa cttgttggac ggacaccact caatacatga
    65881 gagagcagtc cagtcgtact tgtttttccg tgagagcctg ttacagcgat actcgtataa
    65941 ttttggataa aatgaccaat aaagtcgtga tagcgaatca cttccaaacc taattctttt
    66001 gctcgctgga tttcttcatg tgaatcagga aatgcatttc ctgcaatgat cgtcatccct
    66061 ggttttacat tatctgcgtt aaatggcaga atcgtgatat ttgctttttc taaatctctt
    66121 tgtgtaaaga aatatttttc aatgtctgat ccttggacat ttagaccttg ttcatgtaaa
    66181 acaagagcca aggagctcat tcctgaacct ttgataccaa caaaatgata caatttattt
    66241 tgattttcca tttgaatcct cttctcttat ctagcgtcca ttcttttagc tattacattc
    66301 aacacgctcc tcattatctt ataaacgatt gaaaatttca accaaattta tttggaaagg
    66361 aggattcgct tgctaaaatg gtcaagtacg agaaaaatcc gtttttattg actctttaat
    66421 tctggtgtaa gaagaccaaa cttcctctga tatatcaatg tgaggaataa aatcttttcc
    66481 tttcggacca tagccgttct catcgtcatg gagacgttcc atttctccta atactagcgc
    66541 atggaaatat tccttaggcc attgatgatt cagttctttt gctgtaaaga tgatctcttc
    66601 agaaaagtga aggatttccg gcacaaatgg cacagcattc gcgaaaatag tttgttcatt
    66661 ttgccatact ttctcaaaag ttgctcgagt cctgcgttgc agtgtcggat cattcatcaa
    66721 taagattttt tctggtacag ctcctaagga atgaagaatc tccagtgaaa aagtggcgtt
    66781 ctctccagaa tttgtagact tcgattctat cagaaaagcc ttatcgggca aatcatagac
    66841 ttcttttaga tactgacgac agatttcact ttcactcatg ccatcttcaa aatgaaatcc
    66901 ttgcttttca aaattctcat aaaggattct agtcgcatgc cccacccctc cgaccaaaaa
    66961 caattgatct acttggccat ttaaatacat ttgtgctgct ttatcagcta agataggaag
    67021 acagtttcca gctaaaataa gtgtaggtgc cgtcagttcc tcaaaatttc cctcttcagg
    67081 tgcggctaaa aaatttaata gctgattcca gtcttttaga ttcctctgct cacttttttc
    67141 caaaggcctt ctatcctttc atctgatttt ttgtgcttca ttaaagtctt ctctttttgt
    67201 ctcaatccat ttgatttctc catgacatct tccacaacga tatttgcgta catcgattct
    67261 tctcttgcgg cagatcgtgg cagaacaatc ttggcatcga taatactcca tctttatctg
    67321 tttcttcgtc aaggctggtg catagcgcaa ccctcctgtt tttttcaaaa gatacttgaa
    67381 atccatatct ttatgctgat accctcttcc agctagatga agatgataat ggcaaagttc
    67441 atgtttgatg attcctgcaa tcgtctcttc gtctgactct tcaaatagct tcgcattaaa
    67501 atctaaatga tgatcgttta aatgatagcg cccgccagtt gtacgtaagc gtggattgaa
    67561 cattgcttgg tgcttgaaag gaagctggaa gctttttaat gatatctctt ctactaactg
    67621 ctgcagttct tcttgtgtca atttttgtta ctcctcattg ttactcttca taaggggaaa
    67681 gcatcgtcaa actgattctg ccttttttcg tatcgacttg ttctatcaaa actgttacga
    67741 tatctcctac tgacacgaca tctgtaggat gcttgacgaa ttttttgctg agtttcgata
    67801 tatggacaag tccgtcttgc ttcacaccga tatcaacaaa tgcgccgaag tcaatgacat
    67861 tacggaccgt tccagtcaat tccatccctg gtttcaagtc ttccatactc aatacatctg
    67921 tacgtaataa gggcgctggc atctcatcac gcatatctcg tccaggttgt gtcagcccag
    67981 ctaaaatatc ggctaacgtt tcttctccga ctgataggct ttcagccagt ttctctacgg
    68041 ataatcgtgt caatttttct actgcttctt ctgtaccaag ctctttttct gaaagttgga
    68101 ctgaagttaa tatttctttt gcaatagaat aactttcggg atggatacct gtgttgtcca
    68161 aaatgttttt cccaccaggg actcgcaaga atccgattgc ttgttcatat gcttttggtc
    68221 ctaagcgtgg cacttttttc aattgagttc gtgcggtgaa ttctccgttt tcttcacgat
    68281 aaatgacaat gttttgggca gttgttttat tcaatcctga tatatgctgc aagagctgcg
    68341 ggcttgctgt attcacatcc acacctactt ggttaaccgc tgtttccaca acaaaatcca
    68401 attgttcagc caaacgtttt tgagaaacgt catgttggta ctggcctact ccgacagctt
    68461 taggatcgat tttgactaat tcagctaaag gatcttgcag gcgacgggca atagaaacag
    68521 cacttctttc ttcaacttgt agatgcggaa attcttttcg tgcaatttcg ctagcggagt
    68581 aaacagaagc gcctgcttcg ttgacgatag cgtaataggt tttatggtcg gcggatttca
    68641 actgctcagc cacaaaaagt tcagattccc gactggctgt accatttccg atagctacca
    68701 tatctacttg atatttatta attaattgga taaaagctgg tccagcagct tctctttttg
    68761 cttgcgctgc aggtttatga ggataaataa cttcgattgc taaaactttc cctgtcgcat
    68821 ctacgactgc tagtttacat ccagtacgat aagccggatc aaatcccagg acaactttac
    68881 cttttagtgg cggttgcaac aaaagattac ggaggttttc gccgaaaata gcgattgctt
    68941 gctcatctgc cttttcagtc aattcattgc gcagttctcg ctcgattgct ggctgaataa
    69001 agcgtttata actatcctga taggcttctc tgacgaatga agaagaagga gaggcaggat
    69061 ttttgactat ttggcgatcc aagtaagcta aaattgctgc ttcatctact tgaaagaata
    69121 ctttcagaat atcttctttt tctccacgat tagtagctaa tattcgatga gaaaccattt
    69181 tatggacggg ttctgcaaag tcataataca tttcatatac gcctttttca tctgcttgct
    69241 catccttgac attgctgaca tacatacctt tgttatacgt ataagaccga atccaagtcc
    69301 gaaattttgc attatcgctg acttgttcag caataatctc atgagcaccg tgcaacgctt
    69361 cttcggcaga agagacttct ttttctttgt caatatattt ttctgcttca gattgcacct
    69421 ctccatctgt aagctgcatc agccacttcg cgagtggttc aagtcctttt tctttagcaa
    69481 tcgttgcttt tgtccgtcgt ttttgtttgt atggacgata caaatcttcc acttgttgca
    69541 ttttcacggc ttgggtgatt tctgcttcta actcgggagt cagtttccct tgttcatcga
    69601 ttagccgaat cacttcagtt ttacgttttt ctaagttttc aagataggca taccgctctt
    69661 cgatttcacg aatctggact tcatcaagac ttccagtcat ttcttttcgg taacgcgcga
    69721 taaaaggaac agtgtttcct tcatttaaca aattaagtac agtagtcaac tgcttaggac
    69781 gatagtctga aagttctttt tgtacaagct gaatgatcgt ctggttcaaa ttttccgtca
    69841 ttaaaatgcc tcttttctgc taaaaattgc ttctttattc tatcatactt tttatcctgg
    69901 gttaaactac tgaaagaaac aatattctct ataaaaataa aaagagccgc aacaaagtca
    69961 cagctccttc attctttcca ttagtcagat tccatgccaa ggtccttcgt tgttctgata
    70021 ttcaatatct tgaagaatac cttccttgtc aaaaacaacc ccatgcaatg accctccgaa
    70081 tacagcccca ccgtccattc cgattttatg atcctgaatc cagaggtctg ttgtctgcat
    70141 atctccatgg agcattggtg taatcgtatg tccaaataca attgtcttac ctgtattgtt
    70201 tttcccttca tgaaatggtt cccttatcca aataaagtct cttagacttg tcttacgcca
    70261 gtctttcttt gtcaaatcca caccggcatg gacaaaaaga taattttccc attcataata
    70321 caaggggcgc tggactaaaa atttaatcag ttctgaatat ctcgattgga tcatcatcga
    70381 gatttcagtt ggggagtatt cctccgatgc ccctgggtga atcaggcttt caaacgtttc
    70441 ttttccacca tttctcatat aaggcgcata ccagtcctcc ggtgattgca gaaattgcaa
    70501 aaaatattct tcatggtttc cccggaggta aatggctcct gtttcttcga ctaattgctt
    70561 tcctaataaa aaacattctt ttgtacgagg acctcgatca ttgagatccc ctaataaaac
    70621 aagctgatgg atctttggat cataatagtg aataagtttt tcaaaaagct catgtttgcc
    70681 atggacatcc ccaatagcat aaatcaatga tttcatgtgg atcaccatcc tcaacgctag
    70741 tatagcgcat attggaaatg gtcgacaatc aaaactattg ttttctattt aattaaagct
    70801 gtaaaccgca gttctgcttc ttctggagag attccatggt cttgaacata gcgattgcgc
    70861 ggatgtttcg cacactctat gctacatgct cctaaatgtt tttcttcatt ttcaatggaa
    70921 gcaagaatct gacgattgca ctcaggattg ctacaattga tatatcgttc acatggtgtt
    70981 ccgtcaaacc agtcgcgacc gacgatttgt ttatctactt ggttgatatc gacagcgatc
    71041 cgttcatcaa acacatacat cttgccgtcc cataattctc cttggacttc aggatcctta
    71101 ccataagtag caataccgcc atgcagctgt ccgacatctt tgaatccttc acggacaagc
    71161 caaccagaaa acttctcgca acgaatgcca ccagtacagt aggtcactac ccgtttttcc
    71221 ataaattctt ctttgtgctc gcggatccag tctggaagct ctcgaaaact gcgtatatct
    71281 gggcgtacag cccctcgaaa atgtcccaag tcatattcat aatcattccg tgcatcaatc
    71341 accactgtct gttcatctaa aatagcttct ttaaattctt gcggtgaaag ataggcacct
    71401 gtcacttggt ttggatcaat gtcctcttct agctttaaac ttacaagctc tggacggtat
    71461 cttacaaaca tcttcttaaa ggcatgtcct tcgcttggat cgatcttgaa catcgtatca
    71521 gcaaatcgag gatcagcttt cattgctttc atataggcag tcgtgttttc aacggttcca
    71581 gacacagtac catttattcc ttcttcagct actagaatac gacctttaag atccaaagat
    71641 ttgcaaaagg ctaaatgatt tttggcaaat tcctctggtt cttcgatttt tgtataattg
    71701 taataaagca gtacttgata atccatgtat ttcttccttc cttcttttcg ttcctaaaca
    71761 gtataaagaa ggcgttcgca tttgacgatt tatttgcttg tgtataatta cgcatggaaa
    71821 gttttttgtt tacataatat tattatttga attaaaaaga cttcgctttc ctgtttcgca
    71881 cagaaaaaca aagtctttat ttctattatt tacctgtaac cgcaaagtag ttgccatcgg
    71941 gatcagcaaa gttaaagaca tattcttctc caagctgtac catatcacct aatgtgactg
    72001 attgcgtctg cattttttta tatagtccaa agatatcttt actgtaaaac atcaaagatg
    72061 gggcactagt agctgtgcca ggtgaatggg actcaacaaa tgctcgatca tataacagaa
    72121 atgaggtttg actgtcctca actcctactt caattataag cgtcccatcc atttcttgac
    72181 gatctttttc cgcaaagcca actgctctcc aaaacgttgc atttttttct acatcgtcca
    72241 cataaagcat gatttttatt tcattcgtaa acatctgttt cctcctaaac gatctgttct
    72301 aacattctca actttgtcag tttaccatag gaaaatggga aaatctacga aagctctcaa
    72361 cagaatcgtc ctacttaaat acgcttttct ttaataataa ataagttggt tgtttttgtt
    72421 atttgcgctt tcacttttcg gaataaataa tgtgtattta tatggaataa ataaaaaaag
    72481 aggtcgtgac taaaaacaag tcacaacctc tggtaaacgg tgttctcctg acaactcctc
    72541 ggtcacaaga cacaatattc aacaaacatg agaagctatt ttttgaaatt gctctttgtg
    72601 actcagagtg aaacggcagg ctcacgacct ctttct
//
LOCUS       DACGMI010000006        63538 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.006, whole genome shotgun sequence.
ACCESSION   DACGMI010000006 DACGMI010000000
VERSION     DACGMI010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 63538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.006"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(185..310)
                     /locus_tag="IXT46_000487"
     CDS             complement(185..310)
                     /locus_tag="IXT46_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4946429.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(444..1337)
                     /locus_tag="IXT46_000488"
     CDS             complement(444..1337)
                     /locus_tag="IXT46_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAQ4946430.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(1519..2445)
                     /locus_tag="IXT46_000489"
     CDS             complement(1519..2445)
                     /locus_tag="IXT46_000489"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAQ4946431.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(2530..3291)
                     /gene="pflA"
                     /locus_tag="IXT46_000490"
     CDS             complement(2530..3291)
                     /gene="pflA"
                     /locus_tag="IXT46_000490"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAQ4946432.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(3535..5766)
                     /gene="pflB"
                     /locus_tag="IXT46_000491"
     CDS             complement(3535..5766)
                     /gene="pflB"
                     /locus_tag="IXT46_000491"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAQ4946433.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6043..8493)
                     /gene="parC"
                     /locus_tag="IXT46_000492"
     CDS             complement(6043..8493)
                     /gene="parC"
                     /locus_tag="IXT46_000492"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAQ4946434.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(8505..10550)
                     /gene="parE"
                     /locus_tag="IXT46_000493"
     CDS             complement(8505..10550)
                     /gene="parE"
                     /locus_tag="IXT46_000493"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAQ4946435.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(10716..11150)
                     /locus_tag="IXT46_000494"
     CDS             complement(10716..11150)
                     /locus_tag="IXT46_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAQ4946436.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11277..11915
                     /gene="plsY"
                     /locus_tag="IXT46_000495"
     CDS             11277..11915
                     /gene="plsY"
                     /locus_tag="IXT46_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAQ4946437.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12047..12922)
                     /locus_tag="IXT46_000496"
     CDS             complement(12047..12922)
                     /locus_tag="IXT46_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAQ4946438.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(13004..13795)
                     /gene="codY"
                     /locus_tag="IXT46_000497"
     CDS             complement(13004..13795)
                     /gene="codY"
                     /locus_tag="IXT46_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAQ4946439.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(13813..15213)
                     /gene="hslU"
                     /locus_tag="IXT46_000498"
     CDS             complement(13813..15213)
                     /gene="hslU"
                     /locus_tag="IXT46_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAQ4946440.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15227..15775)
                     /gene="hslV"
                     /locus_tag="IXT46_000499"
     CDS             complement(15227..15775)
                     /gene="hslV"
                     /locus_tag="IXT46_000499"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAQ4946441.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(15812..16717)
                     /gene="xerC"
                     /locus_tag="IXT46_000500"
     CDS             complement(15812..16717)
                     /gene="xerC"
                     /locus_tag="IXT46_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAQ4946442.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(16915..18291)
                     /gene="trmFO"
                     /locus_tag="IXT46_000501"
     CDS             complement(16915..18291)
                     /gene="trmFO"
                     /locus_tag="IXT46_000501"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAQ4946443.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18260..20338)
                     /gene="topA"
                     /locus_tag="IXT46_000502"
     CDS             complement(18260..20338)
                     /gene="topA"
                     /locus_tag="IXT46_000502"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAQ4946444.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHGHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(20460..21317)
                     /gene="dprA"
                     /locus_tag="IXT46_000503"
     CDS             complement(20460..21317)
                     /gene="dprA"
                     /locus_tag="IXT46_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAQ4946445.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(21373..22140)
                     /locus_tag="IXT46_000504"
     CDS             complement(21373..22140)
                     /locus_tag="IXT46_000504"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAQ4946446.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22133..22993)
                     /gene="ylqF"
                     /locus_tag="IXT46_000505"
     CDS             complement(22133..22993)
                     /gene="ylqF"
                     /locus_tag="IXT46_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAQ4946447.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            complement(23087..24046)
                     /locus_tag="IXT46_000506"
     CDS             complement(23087..24046)
                     /locus_tag="IXT46_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4946448.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDESFIQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
     gene            24318..24716
                     /locus_tag="IXT46_000507"
     CDS             24318..24716
                     /locus_tag="IXT46_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4946449.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            24953..25495
                     /locus_tag="IXT46_000508"
     CDS             24953..25495
                     /locus_tag="IXT46_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAQ4946450.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(25578..26129)
                     /gene="lepB"
                     /locus_tag="IXT46_000509"
     CDS             complement(25578..26129)
                     /gene="lepB"
                     /locus_tag="IXT46_000509"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4946451.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(26281..26508)
                     /locus_tag="IXT46_000510"
     CDS             complement(26281..26508)
                     /locus_tag="IXT46_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAQ4946452.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(26505..27023)
                     /gene="msrA"
                     /locus_tag="IXT46_000511"
     CDS             complement(26505..27023)
                     /gene="msrA"
                     /locus_tag="IXT46_000511"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4946453.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(27043..27756)
                     /locus_tag="IXT46_000512"
     CDS             complement(27043..27756)
                     /locus_tag="IXT46_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAQ4946454.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(27759..28655)
                     /locus_tag="IXT46_000513"
     CDS             complement(27759..28655)
                     /locus_tag="IXT46_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4946455.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(28813..29655)
                     /locus_tag="IXT46_000514"
     CDS             complement(28813..29655)
                     /locus_tag="IXT46_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4946456.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            29787..30440
                     /locus_tag="IXT46_000515"
     CDS             29787..30440
                     /locus_tag="IXT46_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAQ4946457.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(30503..31030)
                     /locus_tag="IXT46_000516"
     CDS             complement(30503..31030)
                     /locus_tag="IXT46_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4946458.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(31050..31997)
                     /locus_tag="IXT46_000517"
     CDS             complement(31050..31997)
                     /locus_tag="IXT46_000517"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAQ4946459.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(32009..33895)
                     /locus_tag="IXT46_000518"
     CDS             complement(32009..33895)
                     /locus_tag="IXT46_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4946460.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(34055..36133)
                     /locus_tag="IXT46_000519"
     CDS             complement(34055..36133)
                     /locus_tag="IXT46_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAQ4946461.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(36146..36421)
                     /locus_tag="IXT46_000520"
     CDS             complement(36146..36421)
                     /locus_tag="IXT46_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946462.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(36783..37238)
                     /locus_tag="IXT46_000521"
     CDS             complement(36783..37238)
                     /locus_tag="IXT46_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946463.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(37392..38600)
                     /locus_tag="IXT46_000522"
     CDS             complement(37392..38600)
                     /locus_tag="IXT46_000522"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAQ4946464.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(38712..39044)
                     /locus_tag="IXT46_000523"
     CDS             complement(38712..39044)
                     /locus_tag="IXT46_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAQ4946465.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            39192..40067
                     /locus_tag="IXT46_000524"
     CDS             39192..40067
                     /locus_tag="IXT46_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4946466.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(40149..40730)
                     /locus_tag="IXT46_000525"
     CDS             complement(40149..40730)
                     /locus_tag="IXT46_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAQ4946467.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(40736..41995)
                     /locus_tag="IXT46_000526"
     CDS             complement(40736..41995)
                     /locus_tag="IXT46_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAQ4946468.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(41997..43043)
                     /locus_tag="IXT46_000527"
     CDS             complement(41997..43043)
                     /locus_tag="IXT46_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946469.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(43278..43553)
                     /locus_tag="IXT46_000528"
     CDS             complement(43278..43553)
                     /locus_tag="IXT46_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAQ4946470.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(43796..45106)
                     /locus_tag="IXT46_000529"
     CDS             complement(43796..45106)
                     /locus_tag="IXT46_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAQ4946471.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(45288..46517)
                     /gene="rpsA"
                     /locus_tag="IXT46_000530"
     CDS             complement(45288..46517)
                     /gene="rpsA"
                     /locus_tag="IXT46_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAQ4946472.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(46652..47332)
                     /locus_tag="IXT46_000531"
     CDS             complement(46652..47332)
                     /locus_tag="IXT46_000531"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAQ4946473.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(47381..48016)
                     /locus_tag="IXT46_000532"
     CDS             complement(47381..48016)
                     /locus_tag="IXT46_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4946474.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(48082..49485)
                     /locus_tag="IXT46_000533"
     CDS             complement(48082..49485)
                     /locus_tag="IXT46_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAQ4946475.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(49472..50503)
                     /locus_tag="IXT46_000534"
     CDS             complement(49472..50503)
                     /locus_tag="IXT46_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946476.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            50534..50755
                     /locus_tag="IXT46_000535"
     CDS             50534..50755
                     /locus_tag="IXT46_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAQ4946477.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(50920..51657)
                     /locus_tag="IXT46_000536"
     CDS             complement(50920..51657)
                     /locus_tag="IXT46_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAQ4946478.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(51810..53150)
                     /locus_tag="IXT46_000537"
     CDS             complement(51810..53150)
                     /locus_tag="IXT46_000537"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAQ4946479.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(53387..54910)
                     /locus_tag="IXT46_000538"
     CDS             complement(53387..54910)
                     /locus_tag="IXT46_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAQ4946480.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(55289..55900)
                     /locus_tag="IXT46_000539"
     CDS             complement(55289..55900)
                     /locus_tag="IXT46_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4946481.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(56023..56148)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(56230..56946)
                     /locus_tag="IXT46_000540"
     CDS             complement(56230..56946)
                     /locus_tag="IXT46_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAQ4946482.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(56952..57521)
                     /gene="scpB"
                     /locus_tag="IXT46_000541"
     CDS             complement(56952..57521)
                     /gene="scpB"
                     /locus_tag="IXT46_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAQ4946483.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(57505..58302)
                     /locus_tag="IXT46_000542"
     CDS             complement(57505..58302)
                     /locus_tag="IXT46_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAQ4946484.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(58272..58643)
                     /locus_tag="IXT46_000543"
     CDS             complement(58272..58643)
                     /locus_tag="IXT46_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAQ4946485.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(58662..59549)
                     /gene="xerD"
                     /locus_tag="IXT46_000544"
     CDS             complement(58662..59549)
                     /gene="xerD"
                     /locus_tag="IXT46_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAQ4946486.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(59645..60118)
                     /locus_tag="IXT46_000545"
     CDS             complement(59645..60118)
                     /locus_tag="IXT46_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4946487.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(60223..61086)
                     /locus_tag="IXT46_000546"
     CDS             complement(60223..61086)
                     /locus_tag="IXT46_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAQ4946488.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(61282..63381)
                     /locus_tag="IXT46_000547"
     CDS             complement(61282..63381)
                     /locus_tag="IXT46_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAQ4946489.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
BASE COUNT        17227 a        13391 c        10843 g        22077 t
ORIGIN      
        1 tttatgtggc aaagaaaaaa caaacaaaat aaaaagcatt ttgaagcctg actattacga
       61 cttcataaat gcttttttag ttttaaacac ttcaatctaa aagaataacc caagattgga
      121 taaattatta atgactcgcc attcgtttct tagtgattct ggattatcaa atggacttcc
      181 taatctaatc agctagttct tcccataaaa tgccatactt gactgaatca taatattgat
      241 tatttaaaaa tctaactttt cttatcacta cttcctttgt cattccacat ttctcaccat
      301 ttttttgcat tcctttgttt ccagaccatg tagtgaatct aataggtggt agataggcaa
      361 aatactcaaa taattctttt aaccataaag gaagagaaag gctcctcctg caagagtcag
      421 tataattttt gcttactgct ctcttaggtt ttactcacta aaactgttcc atattctttg
      481 atataagaaa atgcatgcgg tataaatttc ttgctcagct cagaaaagat ttgtcgttta
      541 agaaaggcca tttcctccat tgtcaatgaa ggatccaatg ttggtaattc aatctcaaaa
      601 ttgttttttt cgacaatagg taattctaat gtgaatgatt cttcttcctt tatagtattc
      661 gtcacaagta gagactgatg gaaaatacta ggccggcgat ttttatattt attcttacgt
      721 atcctgtcaa cgataacttc tatttgatca aaaaagtacg attcatttac gtctccaata
      781 agttcggcta attctttgaa tgccttcgtt acaggaagct gattcttctg tacaaaaaag
      841 taattagcca aagtaagcgg gaagtgttct atagaggaaa gtgtgataaa acggtacttc
      901 tcatttcctg cagttgtcct cagcaattct gtctctcggc tgtttcttac tccataaaaa
      961 tacgcttctt tccgttcatc ttcgaaacaa tacgcccaaa taacttctcc catcgctaat
     1021 ttttgttcat caacagagag tctcttcaat tgttcagcta tggtttcagc agccgaagtg
     1081 gcttgttgca agtaatcttt aggatcaaat attggaaagt tcaaatgata tcttcgttct
     1141 tccctcttga ttaatcctgc atcgatcaat aaatcaagaa aatgggaaaa tttattttgc
     1201 gaaaattctt ttttcaattc tcttagaatc gtttcttgtt ctcgatgttc atatagataa
     1261 tcggtcaatg aagaaaaaag cggatcatcg gtcagttttt gataaaagtt ttccttattt
     1321 tttgaataat agttcatata tgttctcttt tctatccgtt ttattttact taaaaggctt
     1381 ttacgtaaaa aggaggaaga acaagagtca taattgactg ttattctcct ccatttcttc
     1441 ggcctttagt atgttctatg tttcttttta tatcaatcgc ttatccattc attttgaatg
     1501 cttcatacta ccatttgatt agctaaatac agccgtcaat tgaggtacga cttgtttttt
     1561 acgtgaaacg acacctttaa gcaaagcacg gttgttggtc aaagttgttt ggaaagcttc
     1621 ttctactttt tcttttcctt taccagcaac aagtaattct gaatcactgt ctaagatgtt
     1681 tgtgacaact aatacgaaca gatcgtagcc atttgctttc atttcatctt ccattgctgc
     1741 ttctagctct gcttgtcgat ccatcacttc attaaggtcc actgtattga cttgagcgat
     1801 acgaacgttg gaactgccca ttgggaaact ttttgcatcc aaatcaagaa gaaccgcagc
     1861 tgatttatca cttagatttg ttcctgcttt caacatttca agtccataag tgtttagatc
     1921 gacttcagcg attgctgcaa gttcttttgc agctgcttca tcttcaggcg tacatgttgg
     1981 tgatttgaac aacaatgtat ctgaaatgat agctgagagc atgattcctg cgatttcttt
     2041 aggaattgtt acttggtttt ctttatatag ttttaaaata atcgtacttg tacatccaac
     2101 tggttctgca cgatagtaca atggattagc tgtttcaaag tttgcaatac gatggtggtc
     2161 tactacagct aaaatattta cttcgctgat atctgaaata ctttgttgga attcattatg
     2221 atccacaagc atgacatctg cattttctgc tttagctgac tctactactc gtggtgcaga
     2281 tagctgaaag tggtctaatg cgtattgtgt ttcttcatta ggtgtaccta gagcaactgc
     2341 ttctgtttct ttacctaatt cattttgcaa gtgtgaaaac gcaatggctg ccccgattgc
     2401 atctgtatct ggattttggt gaccaaaaac taaaattttt gacatgtcat tcgctccttt
     2461 gtgatttctc ctatttaata atagcaaaaa aacggaaaga agcaatactt atcttctttc
     2521 cgatgcgacc tatcgcgtta aatattttgt atactcttct gtatgaagca atcgtttagc
     2581 attttcgaca cgttcttttg taggtggttc gatcccttct aatggatatt tcaaaccaag
     2641 tgtttcccac ttgtattttc ccatcgtatg ataaggaaga atctctactc tgtctacatt
     2701 tgacaaggtt tgaataaagt tgtctagtcg gatcaaatat tcatcataat cacttcgctc
     2761 aggaactagt acatggcgaa tccaaaccgg tttgttgatt tttgacaaat attgagccat
     2821 ttctaaaata ttttcattgt cccaatgcgt tagtttttta tgctcttcat tatcgatgtg
     2881 tttgatgtca aataacagta aatctgtata cttcatcaat tcttgaaaac gtgaaaagaa
     2941 aggttcttca tacgtaaaag gttttccgca tgtatccaat gtagtatgca tcttccgctc
     3001 ttttgctttt ttaaatagtt cgatcaaaaa atcgatctgc aatagaggtt ctccaccact
     3061 aacagtaata ccacctttat ctccccagta aggtctgaag cgttctgctt tatctaaaag
     3121 ttcatctgct gtgtattctt tccctccgcc aatattccaa gtatctggat tgtgacaaaa
     3181 ttggcaacgc atgcggcatc cttgcataaa cacgacaaag cgcagtccag gtccgtctac
     3241 tgaaccgaaa gtttcgatag aatgaacata gccgattgtt ttttcttcca tttaagttca
     3301 catcttttct ttgatttcat tttaagtaca agttagctgt cgaagcgaag ctttctgaac
     3361 aaaatttttc gcaattgccg cttcgttatg tgtaaaattt acagggacgg aacatacaag
     3421 tcctgcccct gtaaatcgtt tctttcaaat aagcatactg attattcgat tttgatgcga
     3481 tggctattca acgtcctttc gacgctaagt cgaaaaactt ttttcacgaa ctttttacat
     3541 tctgtcgtgt gaagttctca tcaagacatc taattgttgt tctcttgtca agtcacggaa
     3601 tttaactgca taaccagata cccggatcgt caagttcgga tatttcattg gattttccat
     3661 tgcatcacgc aataaatcat tactgaatac attgacattc aaatgataag ctccttttga
     3721 gaagtatcca tctaagacat tacgcaagtt ttcgattctt gtatcttgtt cttttccaag
     3781 acctgaagga ttgattgttt gggtatttga aattccatcc aatgcacagc cgtaattcat
     3841 tttagctgtt gagttcaggc tagctaataa cccactttgt tccgcattgt aacttggatt
     3901 tgctcctggc gcaagtggtt ttccagcttc acggccatca ggagtatttc ctgtattttt
     3961 accgtaaaca acatttgaag taatcgtcaa taatgaagtt gttggttttg agttgcggta
     4021 agttttatga cgtttgattt gtcccatgaa gtattccaag atccatgaaa ctaattcatc
     4081 tgcacggtca tcatcatttc cgtatttagg gaagtcgcca tccacttcaa aatcaactgc
     4141 tattcctttt tcattacgga ttgcttttac ttttgcatat ttgatcgctg acaagctgtc
     4201 tgccgcatga gagatcccag caatacctgt agcaaatgtg cgttgcaagt cagaatccat
     4261 caaagccagc tgagctgctt cataagaata tttatcatgc atataatgaa tgatgttcaa
     4321 cgtattgaca tatagttctg ctaaccaatc catcatattc atgaagttat gtttcacttc
     4381 ttcaaagtct agtatttctg atgtgattgg acgatattct ggtccaactt gggcgccagt
     4441 cacttcatcg actccgccat tgatggcata taatagtgtt ttagccaagt tagcacgagc
     4501 gccaaagaat tgcatgtctt ttccgacaac tgttcctgat acacagcaag caatcgcaca
     4561 atcatcagaa ccccattgtt cacgaagctg attatcattt tcgaattgaa tcgaagaact
     4621 ttcgatagcg attctgctag catatgttct gaatccttct ggaaggtgtt cagaatacaa
     4681 aacagtcaag tttggttctg gtgaaggtcc catatttgtt aatgtatgaa gcagacggaa
     4741 atcattcttt gtaactaatg aacgaccatc taatcccata cctgcaatgg ataaagtagc
     4801 ccagataggg aatcctgaga ataattggtt atattcaggt gtacgcgcga atttgaccat
     4861 acgtaatttc attactaagt ggtcgatcaa ttcttgtgct tctttttctg tgattactcc
     4921 attatccaaa tcacgttgga tatagatatc aaggaatgct gagatacgtc cgattgacat
     4981 cgcagcacca ttttgtgatt tgattgctgc taaatatccg aagtatagcc attggacagc
     5041 ttcttttgca tttgcagctg gtttagaaat atcatagcca tatttcgcag ccatttcttt
     5101 catttgcgct aatgcacgat attgttcagt gatttcttca cgtaaacgaa tcacttcttc
     5161 actcattgta tgataaccag tcatatcatg atcttttttc ttttgttcca tcaaatagtc
     5221 gattccatac aatgccacac gacgatagtc accgatgata cgtccgcgac cgtaagcgtc
     5281 tggaagccct gtaatgattt tgtttttacg agcagcacgc atttcagcag tataagcgtc
     5341 aaatacacct tgattatgtg ttttgcgcca gtcagtgaaa atatgtgtca attcatcgtt
     5401 tggtgtatag ccattgcttt ttagcgcatt gttagccata ttgattccgc cgaacggcat
     5461 gaatgcttgt ttcaaaggtt tgtctgtctg tagaccgacg attttttcca aatctttatc
     5521 caaatagcct gcatcgtgtg aagtaatagt tgatacgatt tctgtgtcca tatcatagac
     5581 accgttacgc tcgaattgga tatcatttaa cttttgcaat tcatcccata atttttctgt
     5641 tgcttctgtt gggccttcca aaaagctgtc atcaccgcga tattcagtgt agttattttg
     5701 aataaagtct ctagtgtcta cgccttcttt ccatttggta cctttaaatc cattccattg
     5761 ctccattgta tggacctcct aaatttctgt tttatgtaac agtttttacg tgattagtat
     5821 aacacagcac cctatctttg caagggtttt cttgtttttt atttaacaat ttttatgttt
     5881 tatttacata tatttaaatc aacgttgaca taccaacatt taagcattgt gaacactttc
     5941 atcttttttt gcaaacgtat aaggatttat taaaaatgaa tgaaaaagag acgccacctg
     6001 tattaataca gatggcgtct cttcattaaa atactacaac agttacgact cgatgaaaat
     6061 ctcaggagca tcgataactt cgatgacttc tccacctttt ttctcatcca tcgcaaatga
     6121 tccattcgat gttcgatcac ctatagggaa atcagttggg tcaatcgtta actgctgccc
     6181 tttttgattc atcaaggtta tttcttttga tcttccttcc gacatataga taatacggtg
     6241 cggatttttt ttcagctcac gcatgaccgt cactccccgc ttcgcacgtg aagtttggct
     6301 gatttcttga gcaagcatgc gtttaacagc tcctcgctga gtaacgatta cgatcggcgt
     6361 atcaccttct gctaacacaa gcagcccgtt gataatccta tctccatctt tcaaattcat
     6421 agacttcact ccagctgcct ttgctccaac aacgggaaca tctgttaaag gatagcgcaa
     6481 acccattcct tgatgcgtta ctaagaaaac atctaagcct ggctgatctt ctttcagata
     6541 cacagcaatc agttcatctt cttccgcctt tagcttcata cagctgagcg gacggctctt
     6601 ataggtgcgc catggttcga actctgtcat tcgtgtttgc ttgatcaatc cattcttgct
     6661 gatgaataca aatgttttct ctgcttgaat tttttgatat gggaaaacag ctaaaatcga
     6721 ttcgtctaca gacagattgg agattgtttg agaaatgtgc tcaccagcat ctttccattt
     6781 caaatcgggt agttcatgga cagggcggta gatcacattt gctttatttg tgatcagaag
     6841 aacatggtcc aatgtactca attcacctga gtatagcaag tagtcgcctt ctcgcatccc
     6901 gatttcttct ggtttggaag cactataaga acgaaggctt gttcgcttca catagccttc
     6961 tcgcgtcaca ctgacaatta cgtcttcttg tgccactaag acttgcgtat caattttgat
     7021 ttcttcgatt tcgtcttcga ttgtcgttag acgagcggaa gaataatttt ttttcacttc
     7081 tcgcaattct tttttcataa cagagaaaag ctctttgtca tttgaaagga ttttattcaa
     7141 ctctgtgatt tgcgcaatca agctttcgga ttccttttga agctctgtga tatccgtgtt
     7201 cgtcaaacgg tataattgca atgtgacaat tgcttctgct tgttcttctg taaattgaaa
     7261 gacgtcgact aaattctttt tggcgtcttt tttgtcttta ctttcacgaa tcgttgcgat
     7321 tacttcatcc agaatcgata aagctttcat caatccttct acgatatgct gtcttttttg
     7381 agctttggct aaatcgaatt gactacgttt tgttatgact tgctttcgat gctcgatata
     7441 acttcttaaa atgtctttca gtccaacttg atgcggagtc atatggtcga tagcgaccat
     7501 attgaaattg taattgatct gtagctcagt gtttttgaac aaataattca aaattccttg
     7561 agcattggcg tcttttttca attcgacgac aatttgcaga cctgttctat cactttcatc
     7621 tcgtacttca gctattccat cgattttctt attcaaacgg atctcatcca tttttttcac
     7681 caaggtcgct ttatttactt catatgggat ttctgtgatc acgatttgct gtttattacc
     7741 cttcattgcc tctatctttg ttttcgaacg aagaataact tttcctcgtc ctgtttcata
     7801 agcttttttg atttcatctt ttccttgcaa gatccctcct gttggaaagt caggtccagg
     7861 aatatattcc atcaattttt caaggctcgc ttgtggatga tcgatcatat agattgtgcc
     7921 atcgatcact tcagctaagt tatgagtcgg gatttctgtt gcatatccag cagatatacc
     7981 tgtcgatcca ttgacgagaa ggtttgggta tcgagctgga aggactgttg gttctttttc
     8041 tgtatcatca aaattccaca cgagatcgac tgtttctttc tcgatatctg ctagcatctc
     8101 tccacttaac ttggataatc tggcttcagt ataacgcatc gcagcaggtg gatcaccgtc
     8161 catactcccg ttattcccgt gcatttcgat cagtacttcc cgcaacttcc agtcttggct
     8221 catgcggacc atcgcttcat aaatactgat gtcaccatga ggatgataat tccccatgat
     8281 atttccgaca gattttgctg atttacggaa tcctttgtca tacgtattgc catctttgtt
     8341 catggcaaat aatatccggc gttgcactgg cttcaatcca tcacggatat caggcagtgc
     8401 acgttcttgg ataatatatt tggaataacg tccgaagcgg tcacccatca cttcttctaa
     8461 agttaattct tgtacttctt gtcgattttc catcaggtga cctcctattc tacttcaaat
     8521 aactgattgt tttcattttt atctgctcgt tcttcatcta ataaatcatt agaaactgaa
     8581 ggagagattt cagtatcctc ttttttatct aagatactgc catcttcttc gagcgtaaat
     8641 tgcacgtgat tttcgatcca ttttcttcga ggttctactt tgtcacccat cagtgtggtt
     8701 actcgacgtt cagcttgcgc agcatcatcg atacggacgc ggatcaacgt acgggaagtc
     8761 ggatccatcg ttgtttccca caattgttcc gcattcatct ctccaagtcc tttatatcgc
     8821 tgcagcatat atcctttgcc gactttttta atcattgctg ccaattcgtc atctgtccac
     8881 gcatattcaa tgacttgctt ctttccttgt cctttggata ctttatataa aggcggtaac
     8941 gcgatatata ctttcccagc ttcaatcagc ggtttcatat aacgataaaa gaaagtaagc
     9001 agtaatactt gaatatgggc gccgtctgta tccgcatcgg tcatgatgat tactttgtcg
     9061 taattacagt cttcgataga aaactcagga ccgactcctg caccaatcgt atagatcatc
     9121 gtattgattt cttcattttt caagatatct tgcattttag ctttttcggt attgatgact
     9181 tttcctcgta aaggtagaat tgcttggaac tttctgtctc ttccttgttt agcagatccg
     9241 ccagcagaat ccccttcgac taaatacaat tcatttttct tagggtttcg ggattgtgcg
     9301 ggtgtcaatt ttcctgaaag aagagattcg ccttttttac gcttcttccc atttcggctt
     9361 tcttctctgg ctttacgtgc tgcttctctc gcttctctgg ctttgattgc tttacggacc
     9421 aacatctggc tcatttcgct attttcctgc aaataaaagc ccatttgttc actgatgacg
     9481 ttatctacta cggtacgagc aactggcgta ccaagttttt cttttgtttg cccttcaaat
     9541 tgcagaagat tttcaggtac acggatagaa agtacagcag ctaacccttc tctgaaatca
     9601 ctaccttcca gattcttgtc ccgttctttc agcaaaccaa cttttctcgc atattcatta
     9661 taagatttcg tcatcgccgc tttcatacca gcttcatggg ttcccccatc ttttgtccga
     9721 acgttattga caaaagataa aacattttct gaataaccgt cattgtattg ataagcgacc
     9781 tctacttcga taccttcttt ttctcctgaa aaataaacaa ctggtgtcaa tgtatctttt
     9841 tcttcattca gataatcaac aaattctttg attccttctt cgtaatgaaa aatttccttg
     9901 actggttctt ctccacgaag atcagaaaga gagattttaa cgccttttag aagaaaggca
     9961 gattctctta accgttcggc taaaatttca tatgaaaatt tcgttgtact gaatattgta
    10021 tcatctggta aaaaatggac agtcgtcccg tttgcttttt ttgtttttcc tatctttttc
    10081 aaagtaccgt caggtttacc gccgttttta aatttctgct gatactctac gccatctcta
    10141 acgatcgtta caattagcca tttcgataag gcatttacca cactggctcc tacaccgtgc
    10201 agtccaccag aagttttgta ccctccttga ccaaactttc cgccagcatg cagcacagta
    10261 aaaatcactt caactgttgg tattccggaa gcatgcattc ctacaggcat cccacgtccg
    10321 ctatctgcaa cagttatact attgtcttca tggatggtca catcaatctc actgccataa
    10381 cctgataatg cttcgtcaac tgcattatcg acgatttcat agactaaatg atgcaagcct
    10441 cggctgtcag tggatccaat gtacatccct ggtctttttc taactgcctc taatccttcc
    10501 aatacttgga tggacgagtc attgtattcg ttgtttactt tttttgccaa ggcaaacgct
    10561 ccttcaataa tactttgcgg caaaaccgca ccacgattat catactagaa aaggtcgtga
    10621 aaaaaaagag ggtagacgag aaatcaattt taattatctc ctaaccgctt tttcgacatt
    10681 cccctctatc gatcatctct tctttgtggt catttttatt tttggttttc tttcaactta
    10741 ccaagttcaa tcttaataca acgatccatt acgatatctg tacgtcctgc ttttcttagc
    10801 atctcagctg cttctttgtt ttcaatccct aattgtgccc agaacacttt agcatcagtt
    10861 ttcaaaaaat cacctgctat ttcaggtaaa aattcactcc gtctaaatac atctacgata
    10921 tcgattggat catcgatttc tgtcaaattc gcatagactt tctcgcctag aatttcttca
    10981 ccagccaata atggatttac tggtatgatt ttatatccat tgtcttgcaa tacctgtgca
    11041 accatgtaac ttgttcgttc tggtttattg ctcaagccta cgacggcaat attttttgct
    11101 tcttccaaat agttgaaaat cgtttcttgt gttggatttt ttacagacat ttctgccacc
    11161 ccttgctttt ctttttattc catctattat acttgtatct ttcatttttt caattgttcc
    11221 tgttacctat tcatgctaaa ataaaggata gttttcaact tgaaagaggg taaaaaatga
    11281 aattgatctt attacttatt ttagcatatc ttttaggttc tattccttcc ggtgtctgga
    11341 ttggcaaatt gtttttcaaa aaagatatcc gacaacacgg gagcggtaat actggaacga
    11401 ccaatacatt tcgtgtatta ggcaaaacag ccgggattgt tgtcctgctt atggatattt
    11461 taaaaggtac attggctact tgtttgccga tgatcttcca cctttctggg attaaccctc
    11521 tttggtttgg ggtatgcgcc attcttggcc atacatttcc gatttttgct gggttcaaag
    11581 gaggaaaagc tgttgcgaca agtgcaggaa tgcttttagg atttaatcct gtattttttg
    11641 tttattcttg tatcatcttt atcgttagtt tattttgtac aagtatggtg agtttgagca
    11701 gtatgatcag tgcagtattg atcactttat ctacgatcgt ccttccttat gtagctcctg
    11761 tgattttggc taagcccaat tggttactga cgatcattgc ctttttagtt tcttccttta
    11821 tcttttatcg gcataaagac aatatcaagc gtatcagaaa ccatactgaa agtcgaatcc
    11881 cgtttggttt gaatagcagc aagaaaaaat cctgatactt tttcattcca aagagataaa
    11941 acgggagtgt gacaaatcga tgtcacactc ccttattact tacaggatag cttttttaca
    12001 caccttggta aacggtgttc cctgctaact tctcggtcac aacctcttac ttcactgtga
    12061 tggaatattt tgtcttgaag atttcatggg cacctagttg attgatccct actttttcca
    12121 tcaagtttcc actactgttc accgtgtcag cgattccgca ccacggttcg atacaaacga
    12181 aaggcgcttc ttttggataa ggagaccaga tccctacata aggcatatct ttatagctta
    12241 aagttacgct atgggaagat ttttcacttc gaatggcgta cgcatttaga ccccttgttt
    12301 caaaaaccaa ggcatcttgc tcaaaaagtt cacgattcaa agccagattc gtatttgtct
    12361 gacctaacgt cttttgatcc atatcgatga atgggccttt caatggtagg cgtaatcttg
    12421 atttcaatgg agaaaatgcc agatagaaat cttcaaatga caatccttct tcaagaggta
    12481 cattgaaagc aggatgtcca ccgatagaaa agaacatttc tttttcaccg gtatttgcca
    12541 cttgataatg aaccgtgatg ccgtctcctc ctaattcata gctgatcact aattcaaaat
    12601 caaatggata cttttctaat gtctccggcg tactccttaa gatgaaacta gccatttctt
    12661 gtccatgttc aatgacttca aaatccatat cccgagcaaa tccgtgttgc cccatttgat
    12721 atgttttccc ttgataaaca tactgatcat cttttaaacg tccaacaaaa gggaataaaa
    12781 ccggtgcatg tctgccccaa tacgctggat caccttgcca gatatactct aaaccatgtt
    12841 cttttgattt cagactgatc aattccgcac cgtgttcagc gatttcggcg atcagctggt
    12901 cattttgaat aataacagtc attgccattc ctccaacttc gacttacttt ttaaaatggg
    12961 aaggctggaa caaacatttc tatctgcccc agtcccctta cttctaataa ctgtgttttg
    13021 ctaactcgtc tttaaaacgg gaattcaata cttttaaata agttcccttc atgcctaacg
    13081 aacgagattc aatgattcca gctgattcca attttcgtaa agcattgacg atcacagaac
    13141 gagtgatgcc gatactatcg gcaatattag aagcagtcag acgaccttca tctccatcca
    13201 atgcttcaaa gatagcttgt acagccttca attcgctata agataatgtg ttgattgcca
    13261 tttggacagc cgttgcactc cgtacatctg cttcgatgct tcgagacttc tgataaagga
    13321 tctgcatacc gacaaccgta gctccatatt ctgctaagac tagatcgtca tctgcaaacg
    13381 attgttccat acgagataag ataatcgtac ccaaacgttc gccagctcca aagatcggaa
    13441 cgacagtcgt cagaccaaat ggatatttct ctcttgactc taccggaaat gcagtaatat
    13501 cactagtaat tgggatatta gcttcagttt tcatcaactg tgccactgta tcagtataag
    13561 attcaggaaa ttgtttctca acaaacattg ttttgattcg ttcattgttc acatcgtgac
    13621 gttcattata acctagtaat actccgtcac ttcctatgat ataggtgttg ctgtcaagaa
    13681 taccacctag tgtgacagcc attttatcgt aaggcaaatc tgcttgcatg tcaaaagtat
    13741 tcttttgctg caaaagtgtg tttatcttgc gggttttcgt tagcaagtct gtcattgtcg
    13801 tcctccgatt ttttataaaa tatagcgact taaatcttca tttgccgcaa ttgagccaag
    13861 tttgtcatcc acatatgctt ctgtgatcgt tatttctccc atttgcatat ctggtgcttc
    13921 aaataataga tcttctagta gtttttccaa aatggtatgc agtctgcgtg cgccgatatt
    13981 atctgtgtca cggttgacat cgaaagcgat ttgagcgatc cgttcaattg cttcttttgt
    14041 aaacgtaact gacacatttt ctgtaccgat caacgcgacg tattgtttta ctaaagcatt
    14101 atttggttcg gtcagaatct tcacaaaatc ttcagctgtc aaatcatcta attctacccg
    14161 tatcgggaag cgtccttgaa gttctggaat tagatcactt ggtttagaca aatggaaagc
    14221 tcctgaagca atgaatagga cgtgatctgt ttggatgatc ccgtattttg tgtttacttg
    14281 tgaaccttcg acaattggca atatgtctct ttggacgcct tctctggata cttctccaga
    14341 ttgctgtgat ttagaagtga tcttatcgat ttcatcgata aaaataattc cactttcttc
    14401 cgctaatttg attgcctcac tatggatatc agcatccttg actaattttg ctgattcttc
    14461 cttgatcaat aactctaaag cttctttgac tgttaccgtc cgttccactt ttttcttcgg
    14521 tgtcaaagca cctagagttt catttaggtc gatccccatt tgctccaatc cattgttcat
    14581 cattggtgca ggtttctttt ggtcttcaac ttcaatggtt acttcacgac tatccagtaa
    14641 acccttttgt agttgttcca agactgtacg gcgattgatt cgaatatctt ctgtcacttc
    14701 ttcttgcggt tcagcggtat tttgctgact agcattaaaa agattcatca tttgttcaaa
    14761 ttgattagtg gattgtttct gttctttttt gataccaggt accaagattt ttaccaaacg
    14821 tttttctgca ttttttttag cacttgtgta tacacggctg tactgctctt tttctacgat
    14881 ttggatcgca ttttctacta aatcccgaac cattgattct acatctcttc cgacataacc
    14941 gacttcagta aattttgttg cttcgacttt gacaaatggt gcattgacga tttttgccaa
    15001 acgtcgtgcg atttctgttt taccgacccc tgtaggtccg atcatcagca tattttttgg
    15061 tgtaatatct tgttgcattt tttcatctaa ctgcaaacgg cgatagcggt tacgcaaagc
    15121 aacggcaaca gatttttttg ctgcgtgctg tcctacgata tattcatcta attcacttac
    15181 gatttgtctt ggtgtttgtt ttaattcata catatctact cacctcttac agttcttcta
    15241 cgataatatt atgattagta aagatacaga tatctgcggc aatatttaac gcattttctg
    15301 caatttcttt cgcactcatg tcgttttgag catagttttt cattgctcgg gctgcagcca
    15361 acgcaaaatt ccctcctgat ccgatagcta agataccatc atctggtgtg ataacttctc
    15421 ctgtacctga aacaagaagc atttctttat cattcattac gatcagcatc gcttcaagtt
    15481 tttgcataga ttgctgtgtc cgccattctt gagctaattc gacagctgcg cgttgtagat
    15541 tcccgttata ttcgtttagt ttgccttcaa atttttcttc taaagtaaac gcatctgcaa
    15601 cacttccggc gaaacctaca acaacttctc cattgtagat acgtcgtact ttctttgcag
    15661 tgcctttcat gacaacagat tcacccattg ttacttggcc atctccagcc atagcaaatt
    15721 tcccgtcttt ttcgacggca cagatagtgg ttgaatgaaa tggtgattcg accatgtttg
    15781 tttcctccta aatttgttct tttccttatt tttacgctct tggatggaaa gaacgatagt
    15841 ttttttgtaa actttctttt gttacatggg catagatctg ggtagtcgat aaattggcat
    15901 gtcctagcaa ttcttggact gtccgcaaat ctgccccatt atttaataaa tgagtagcaa
    15961 atgtatggcg cagcatgtga ggatggatat cactatccaa actgcttttt ttgatcattt
    16021 gattcaagac atattcaatt ccagtaggcg tgattggttt tccatgatga ttcacaaaaa
    16081 cgatatcatg ctcttcgtga tattttgtca tcaatacctg gcggccttcc ctgaaatatt
    16141 cttgcagagc atcttgagca aaagaaccta gaggagcata tctctctttg ttccctttac
    16201 catggatcaa catgacctct gaatcaaaat caatgtctga taccgacaaa ctgctacact
    16261 cacttaaacg gatgcctgac ccgtaaagga cttccagtaa agcgcggttc ctcaaatcca
    16321 aaggactatc tcctgctacg ctgtcaaaaa gtgcttgcat ttcattttca taaaaaaaac
    16381 gtggcagtct caaatttttc tttttgagat gaacgtaaga aaatggattt tcttttatca
    16441 cttcttcttt gagaagatac tgataaaacg aacgtaggct ggctatcttg cgactgatag
    16501 aatttctgct atagctagga cgatgatcag ctaatgcact caaatagaca cgaaccgtaa
    16561 aatattccgc cttcagcaga tcagcgtctc cagattcctc caaaaaatgt ttgaaatgga
    16621 gaatgtcttc ttcatatgct tctttcgttt tttctgaata tcctctttcg acaatcaaat
    16681 aacgcaaaaa tttttgttcc cacgtggctt ctgtcatttt ctcaccttcc ttttgtccca
    16741 gagaataatt tagcacagcg tttataaaaa gacaaataaa ttgtcagaat ttaaccaata
    16801 tttctaagtt tgttcacaat tggcgcaatt cctcacattt tgtttgagaa attcttaaga
    16861 aaaacgcaag aaaaagagcg agactatccg tctcaccctc ttcatggagt ttccttactc
    16921 atttgggatt gcagtttttt ctaattctgt ttttattgcc tcattagctt ttaaagctcg
    16981 ttgtgcaatt gcttcatatc ttgctttttt gtctcgaatg cgctctggca gttcaggaaa
    17041 cagaccatag ttggcattca tcggttggaa atgttttcct tccgcatgag taatgtagta
    17101 agccatactt ccaatagctg tttcttgtgg aaactcgact ggttccattt cttttgctaa
    17161 gcgtgcggcg ttgattccag caagtagtcc gctcgctgca ctttcaacat agccttctac
    17221 accagtcatc tgacctgcaa agaacagatc ttcgcgtttc gttgattggt aagtcggttt
    17281 cagcaattct ggcgaattca taaagctgtt tcggtgcatc acaccatagc gaacgaattc
    17341 agcattttct aacccaggaa tcatccggaa aacacgtttt tgctcgcccc atttcaagtg
    17401 agtctgaaag cccacgatgt tgtataaaga agctgcagca ttgtcttgac gcagctggat
    17461 aacagcataa ggacgtttgc cagttttagg atcttccaat ccaactggtt tcataggtcc
    17521 gaaaagcatc gttttgaatc ctcgctgtgc cattacttca attggcatac atccttcaaa
    17581 atatttttct ttctcaaaag atttaagttc tgccacttcg gcattgatta gtgcctcatg
    17641 gaaagctttg aattcctctt ctgtcatcgg acagttcaag taagctgctt ctcctttgtc
    17701 atagcgggac ttcaaatata ctttatccat atcgatcgta gctttgtcta cgattggtgc
    17761 agctgcatca tagaaataaa aaccatctga accattgaat gctttgatgc tttctgctaa
    17821 tggatgagaa gtcaaaggtc ctgttgctac tacggtgatt ccttccggta tttcagtaat
    17881 ttcttcgttt atcactgtta ctaatggatg ctctttgact tttcgggtaa ttgtttcaga
    17941 aaaagaatcg cggtcaacag ctaaggcacc accagctggc actgctgttt catctgccga
    18001 agtgattact accgaattca atcggcgcat ttcttctttc aataacccta ctgcattagc
    18061 caaactgttt cctcttaatg aattggaaca tactagttca gcaaaattac ttgtgtgatg
    18121 cgcctcagtc gatttgactg gacgcatttc atataaacgg acagggactc ctgcttgtgc
    18181 gatctgccaa gcagcttcac ttccggcaag ccctgctcca acaacattta ccattttcaa
    18241 tgaaagaacc tcttttctat tatttttgga tgtcttcttc gtaatctcca tttacacaga
    18301 ctacttgttt accgcctttg actttcttct cgaccagata tccgtcacat tttggacaat
    18361 ttctgcccac tggtttatcc caagaagtga attcacattc tgggaaacgg gaacaaccat
    18421 agaatagtct gtttttctta gattttcgtt caatgacttg tccttcatga catactgggc
    18481 aagtcacacc gatttctttt acgattggtt tcgtattccg acaatcagga aaattactgc
    18541 aagcataaaa cttcccatat ttccctaatt ttatcaccat cggatgtcca cagacatcac
    18601 aatcgaatcc tgctggttca tctttgattt gaattttttc gattttttct tccgcattcg
    18661 tcagttcttt ttcaaacggt ttatagaaac gatcaaccac tttgacccac gcttccgtgc
    18721 cttcttcaat tttatccaaa tctccttcca tttctgctgt gaaatggata tcgacgattt
    18781 gagggaagaa ttcacagatt aatgaattga caatttctcc tagttcagtc ggctcaaatc
    18841 ttttttgtgt caattttaca tagtagcgtc tttggatcgt atcaagtgtt ggtgcataag
    18901 tggaaggtcg ccctaccccg ttttcttcta gtgcacgaat caacgtagcc tcactaaaac
    18961 gtgctggtgg ttgagtaaaa tgttgttttg gttcaatatc aacagattgg actacatcgc
    19021 cttcttcaag ttctggaaga atattttctt tctcttcttt gccgtcatct ctaccttcca
    19081 catacacttg catgaatcct ttgaatttga tttttgaacc gttcgcaatg aagatgacac
    19141 cattttgttc taatgtcact ttcattgtat ctaaaatagc tggtgtcatc tgactagcca
    19201 caaaacgtga ccagatcaat gtataaagtt tcaattgatc tttatctaaa tattgtttga
    19261 gttcatctgg tgtacgaagc acactcgttg gacgcacagc ttcatgggca tcttgtgcgc
    19321 cttgagcatt tttgatcttt cggtgaccat gtctagaaaa ttcttttcca tacgtatctt
    19381 caataaatgc tgcggcctct gcttttgctg tatcggcaat ccgggtagaa tcagtacgca
    19441 tgtatgtaat caagccgact gttccttgtt tacccaaagt gattccttca tataattgct
    19501 gtgctaccat catggttttt cttgttcgaa agtttaactt acgggcagct tcttgttgca
    19561 ggctacttgt agtgaaagga ttcgcagggt ttcttttgcg ctctttcttt tctacttttt
    19621 taacttcgaa gtctgttcca tcaattctag cagtgacttc ttttacactt tgtgcatctg
    19681 gtaatttctt tttcttaccg tcgattcccc agaaatttgc tttgaatttc ttgcgagctt
    19741 ttttaaaatt accgtcgatg ctccaatatt cttctggaac aaattctcgg atctcttttt
    19801 cacggtcaat aataattttt aaagcgacag attggacacg tcctgcactt aaccctttct
    19861 tgaccttacg ccagagaata ggactgatcg aataaccaac gattctgtct aaggtacgac
    19921 gagcttgctg tgcatctact aaatctacat cgatcgttct tggttcctta aaagctgctt
    19981 tgactgcgtc ttttgtgatt tcattgaaga ccacccgatt tttttctttc agatccaacc
    20041 caagtaggta cgctaaatgc caagcaatcg cttctccttc tctatccggg tcacttgcca
    20101 agtaaacttt ttgagctttt tttgctgcgg ctttcaggct tttgatgaca tcgccttttc
    20161 cgcgtataga aatataatgg ggttcataat tgttttcaaa atcgataccc attttacttt
    20221 tcggtaaatc tcttatatgg ccaacactgg ccattacttt atagtttcgt ccaagatatt
    20281 tctcaattgt cttggctttt gcaggtgatt ctacaatcac taaatattta tacgccatta
    20341 ctgaatggac tcctttccat tgtcgtgttc ctactattaa aagaggattc atacaaatcg
    20401 tagctaatca tatccattca gaaaacgttt gtcaagaaaa gcaaatgaaa agtatggtgt
    20461 tattctttaa attctgccaa gatatcttca cccgaaaccg tgcaaactgc accgtcttgg
    20521 atcaaatgat gacatccggt agaatgttct gttaaaatat ttcctggaac agaaaaaact
    20581 gttcttccaa gatccaatgc ttgctgtgct gttatcagag agccgctttt tttcttggct
    20641 tcaaagacac atgttccttt agacaaagct gcgataatcc gatttctcat tggaaaacaa
    20701 tgctttttcg ggccggattg aggaggatat tcactcaaaa gaagatgatc atttgcaatc
    20761 acctcttgca agtcacgatt ttcagcagga tagacttgct ctatccctgt tccaatgact
    20821 gcgattgtcc gtccaccatg agagattgct gcttggtgac cgtatgtatc tatccctttc
    20881 gcgcagccac tgacgatcac atatccagct tctatcactg gttttagtaa ataataaact
    20941 gtttttttgg ctaaagcaga agtgtgtctt ccaccaacaa cgcttaacat gttacaagaa
    21001 agtaaagata gatcaccatt ataaaacagt acaattggcg gataggtcaa gtgaagcagc
    21061 tgagggggat atttgggatc aaagcaagtg ataaacgact gtttcgattg gattttgccc
    21121 cagttagcgt gaatttcctg ccaacttttg cgaaacagct cccggtgttt ggttatttta
    21181 cctatcttaa tgatgtcttc aaatccgatt tctttataag gatactgcat catccagtta
    21241 gcaagtgccc attttccttg actactgatt ccttttgtat aagcaagttt caataaattt
    21301 tcttctattt gatacatcat aaaaccgcct ttcgtctctc tttctaataa gatacgtaaa
    21361 agcggctgtt ttttattgta aatatttttt tacaggtgca aaacttttac gatggattgg
    21421 cgtaattcct tgtcgttcaa gtccttctaa gtgttccttt gttccataac ctgcattatg
    21481 cgagaaacca tatccaggat aaagcacgtc atattctttc atcaattggt ctcgatatac
    21541 tttagcaatg atacttgcag cagcaatcga cacagatcgt gcatcccctt tgattatttt
    21601 ttcctgctga ataggcaaat ccaaggtcat cgcatcgatc aacaaatagc ttggtacaat
    21661 ggacaatttt tctactgctt ggatcatcgc taatttactt gcttcataaa tattcacatc
    21721 atcgattgtc tgctgatcaa cgatcccgat cccgattgcc agggcttttt cttgaacttg
    21781 ttgataaaga agttctcgct ttttctctga taattgtttg gagtcattca gccctaatat
    21841 gatctcattt ttcggcaaga taactgcagc tgccacgaca ggtccagcta atggtcctct
    21901 tcctacttca tcaatgccgg caatccattg gtgaccttgt gcgtaccctt gcttttcaaa
    21961 gcaaaacatt tcttcatatt tttccttaat taatgcttcc tttttcaatc gtcgttcaaa
    22021 agaagccagt gcttgctgca cgcctttgcg tggatcattt cttaatgatt ctagtgtagg
    22081 atcatctatt ctctgtatgc ttttcaatcg ttctttgata ctttggatgg attcagtcat
    22141 cacttttttg ctccatttct tcgcaacgat ccagtgtgta tcgtccaagt tttccttgac
    22201 gaatatcatg cacgactaat tcgctgccac gatcatagtc ttctttatac ccacgttttg
    22261 ctgtaatatc catcagtaat tccggtgcca atttttcttc ttgctcgatt gataaaccat
    22321 aacgatcgct gattcttcct gaataatatc gggcaaaaaa gtctaatccg taaatcgcta
    22381 aatcatctaa atggacaagc tggtctttga tcgcgcctgt cagcgctagt tttttgccga
    22441 tttcttcatc ttcaaatttg ggccataaaa tccctggtgt gtctaacaat tccaactcat
    22501 tacctaaacg aagccactgc tgaccttttg ttacgccagg cttatttcct gtctgtgcaa
    22561 ttttcttgcc tactagtcga ttcatcaacg tagatttccc aacatttgga atacctaaga
    22621 ccattgcccg aatagcgcga ggcttgatcc cccgagcagc atctcttgcc cgtttttctt
    22681 tcaatgcttc tttagccgca ggtactagac ctttaattcc tttactttct tgtgccgtga
    22741 tagctaatgc aagatggcct tgtttacgaa aatattcttg ccacagcttt gtctgttgtg
    22801 gatctgccag atccgcttta ttcaataaaa caaggcgagg tttttgctga atgatctgat
    22861 ctagcattgg attacgagaa gataaaggta atcgtgcgtc taccaattca aatacgatgt
    22921 ccacatattt cattttttca gaaacttctc gtcgggcttt tgccatatgt cccggaaacc
    22981 attggatggt cattgttctc tccattcctt tcataccgga atattccccg gctttacttg
    23041 tttttttctt tttcaatata aattcacttt tttattatct taattgtcaa attaagttag
    23101 acaaatcatc aatacttacg taactcaaaa atacttccaa aggtgttcga taattcagtg
    23161 attttctagg aatattattt cgtttcgatg cgacagattg aataaaagat tcatctactg
    23221 aattgaaatc catagatttc aataaaccat ctctacgtaa caatccgtta gaattctcgt
    23281 ttaggcctct ttgagacggc gttcctggat cagcgaaata aatggcaata tcattggcat
    23341 tactgatctg tttccaattt gaaaattcct ttccacaatc aaaagtgatg gatttgaata
    23401 gatttttcgg tacagattca aaccaatgat ttaatttgtt ttcaatatca atcgcttgtc
    23461 taccacacgg tttcaatgtg atgataactt ttgataatcg ctcaactaag gtaattacag
    23521 cacttttatg tttcaaacct acgatagtgt caccttcaag gtgaccaaac tcatttgaga
    23581 attggctata atctttttca cgttcatgaa tagagcgacg gaaagcttgt tttccacgtc
    23641 tttcttgatg tccatttggt ttacgcttgc ctttcatcgg taagtcagaa ggattaaata
    23701 gccccttttt gaacatacga taaatggtac gagcagaaca acgaatagga aacgctgcac
    23761 gaccaacaat cacatcgggt gtccatcctt gaacaacctt tctttgaata tattctgatt
    23821 gttcctcagg taaaacaagc gggcgtctac cacagtttga tttgtttttc ttatactgtt
    23881 gatagtactc taaggctgat tttccttgct tgaagaacag gtatacttta tggatcgttt
    23941 gtcttgaacg attcaagaaa tgcgcagttt tcgcaacaga ttgatttatt ttgaaataag
    24001 actctatcat tacaagttca tccgttgtaa gatgggtata ggtcatttgt actcactcct
    24061 tataattctt tggacggaac tattttgagt gtagcacaaa tgactttttt agttgtctag
    24121 cttaatttta caatcggcgt tataaagaaa ttccatctat tagttaagtg aaagtgaacc
    24181 agtcctcatt ctatcacatc ttcacttttt tgatgatgca aatttttatt ttggtttcta
    24241 tatatgaatc taaatttttg acagcgtttc ctaaataaga gatgatagac gaacaaaaca
    24301 gaaaggagac gaaacaaatg aatagtatgg tttttgttaa ttttcctgtt gctgatgtca
    24361 atcgttccgt tgctttttat gaaaagctgg gttttaaaaa aaatgaagaa ttttctactg
    24421 aagaagctgg ttcaatggta tgggatgaca ctttttggat aatgcttctc tctcatgatt
    24481 tttataaaaa atttataaaa gataaagaaa tagctgataa taaaaaaaca agtggtgctt
    24541 tgatttcgtt tagtgttgaa aatgcggatg aagtaaaaaa atttgctcaa attgcaaaag
    24601 aaaatggtgg tactttccac gaagtagata tgggaatgcc tgaagaagaa atgttttcat
    24661 tagaagtcca agatctagac ggaaatacat tagaacccgt atggatgaag atgtaagcag
    24721 ataactaatc tgacgttttt tataacaaaa aaacaaaggc ggatgatacg ataagtattc
    24781 tccgcctcta ttttttttat tcgtacaatc tcttttttac agtttataaa agcagtcttc
    24841 tcaccctttt tttaattgtt agatgccagt gtatgtaaat caccaatgtg tcatgacaca
    24901 ttggtgattt tatggtatcc ttttattatt aactgacaaa ggagagaata ttttgaacac
    24961 tttgattgca aaagacgttt ttagattgcc cgaaatgaat gcaagattgt tgtcgacctc
    25021 tgctctttta ttagcccttg atgtcatctt atacaagata gcgattggtc ctgcttattt
    25081 tcaaatcaca ttcggatttt taagtatggc gcttatgggt tatctatatg gaccgatctg
    25141 ggctggtttg cttgaaatgt tgtcgaacac tttaaatttc acgatatttg gttcaggaac
    25201 gtttcaagct gcttttctta tcacggcttt ccttggtgga tttattaatg gcttattttt
    25261 atatcataaa aagataaacc tgccttccgt catcgctgcc caattattga ttatgatccc
    25321 agtcagcctt tttatcaatt cttggctgat gtctgttttg tttggtgcag atttcaaagt
    25381 aatttttcta ggtagattca tcaggaatat gatccaaatc cctattcaaa taatggttgt
    25441 ttattcattt atcaaaactt tagaggctag aaaagtgttt aaacgagctg tttgatttta
    25501 cgtactaagg tagtaaactg attttggatt aaacaataaa gcgtgcagtc tcaacagact
    25561 gcacgcttta ttgtttctca ctggatccat tttatttcat caagtggata atagacaaat
    25621 cttgctttac ctagaatatc agttttattg atcgtgccaa acgaacgact atcttttgaa
    25681 actcttcgat tatctccaag tacaaaataa ttatcttccg gaagcttgga ttgtcccgtt
    25741 agctcttgta gtgtaaagtc cgtcgtatag gatgcatttg catgatctga tttcaggttt
    25801 ttagttagat aaggttcctt aactactttc ccattgatct tcaattgatc attttggtag
    25861 ctgacatttt ctcctggaag accgattact cgtttgatat aaatcgtgcc atctgctaat
    25921 tgaaaaacaa caatatcaaa tcgtctgatc tccgaaaatt tttccatcac aaccatatca
    25981 ccttgcttca acacgttttc cattgaattg ccttccactg gtaccgggat gaataaaaat
    26041 ccccgcaaca tgaacgcaag gaatacagaa acaagtaagt atttgaatac aagccagaag
    26101 cgattaatat agcgttgttt ttttgtcaat ctctatcaat ccatccctct ttttttcatt
    26161 ctttctttat tataagaaaa atatcaaaaa aatgcgacta gatagctgaa ataaaaataa
    26221 ttctttcaat taggctattg gacaaaaaac ttttttgatc ataaagtaca aaactatctc
    26281 ttatatgtca tgattatttt ctaaatattt ttcccatgct tcgtcaaaga tatccatgga
    26341 cggcaaatag tcgacattca gttccagata attagaaatt tcttcgtagc tagagctgtg
    26401 cttaggaaat tggatgtctt taccggcttc tgtagcgaaa acagataaag catcatgtgt
    26461 gccaccgcct cgcagtgtca ttaaataatg aaaaaagctt cgattcaccc ttcgttcctc
    26521 caattttctt cgataaaggc agcccggcgt gcatggtttc ttttaaaatt ttcaggatgc
    26581 tttttataat actcttgatg gtcttcttct gctagataaa atggttgggc tggttcgatt
    26641 tttgtaacga ttggctgttc gaaacgtcca ctttcagcta actgtttctt acttttttca
    26701 gcaatgatcc gctgttcttc tgtcaaataa aagatcaccg ggcgataatt gtcaccgcga
    26761 tcctcgaatt gtccgaaagc gtcagttgga tcagtttgct gccagtaaag ttctactaat
    26821 tgttcatatg aaatcaatgt tggatcatag ataatctcca ctgcttctgt atgtccagtc
    26881 gtttggcttt ttacttgttc ataagtcgga tctggtacat gccctccagt atatcctgac
    26941 atcactgtat ggataccagg aagcgtgtcg aaaggctgga tcatacacca gaagcagcct
    27001 cctgcaaata ttgctcgttc cattatgatt ccccctctaa tactactcat ccgatgattt
    27061 tttattttct tttgtcttgc tttcagtact gctggtgcta gttttgttgg tatttgagtt
    27121 gtttgaagca tcagaggtat cttttggcaa atatagacta aaccgaatgt catcatttac
    27181 taagtcgatt ttatctgctt taatatacat cccgttttgc attcggaatt gatccaacct
    27241 aagcatgata gtcagatcat ctgtattgac ttcgatccaa tctggtaatt tatagtttct
    27301 cttgatcata ttcatcacat ctttgattgg caaactcaat gttccgatag aaagacttct
    27361 agcttttagt tggacatttc cgttttccat cacatacgga tcaaaatata aatagaaatc
    27421 gataggaaaa cctagtactt cgaaagtacc attgagtagt gcttcatttt ccaaataaaa
    27481 tttatattca atatcactat ctttttgata ctcactaagg aaaaagctga tgatttgatt
    27541 gactttttct ttatttgaat tgatcgttaa gacaggatct ccttgtcttt ccgtaagagc
    27601 tggtatttct gggagttctg gttcccgatt agcaaaaata cggctgccta aaaatacggt
    27661 cgaaccaagt actaccccaa gaaggataag gaaggcgaat ttccagtaat ttgttttctt
    27721 tgttttgttt gaagatacgt cagatcttgt tttcatgttt attgatcatc ctccttctct
    27781 aaccattggt tttgtgtctc gatcagctga tctctcactg catttgccat caattgataa
    27841 cctaaattat ttggatggaa atgatcttct tcatagagca cattattttt gatgccattt
    27901 agattttctg tcgtgctagt tgtttgatct gttccttctt ctgtgacacc tacttcctga
    27961 ttcaatcctt gataaagcaa atcattgatt gggataaagt agcagttcgg catttttttt
    28021 gtcaccgttt ctgttccttt gttccaattg ttaacaattg tctgcatgtc agtgatctca
    28081 ggaaagttca aataaaatgg attgtagatg cctaaaatgt aaataggtgc ggttttattg
    28141 agggatcgaa attcttccaa tagttctgtg acattttcct gatagttttt cagtggcttt
    28201 ttaaaggaat tgaccgttaa cccgaataaa ttattttgga taactttcat caaatcatta
    28261 ccgccaacag tcagtgtgat aaaatcagct gttttgatat tgtttcgaat ttcttctttt
    28321 gtttttactc gctttaagat ctggtcactt cgttcaccat ttacaccata gttttctgtt
    28381 tcaaccgcgg tcaaattata acggtctttt agatcatttg cgacaagggg aacgaatcct
    28441 ccttgcttgg tttgatctcc tactccttca gtcagcgaat ctccgatagc tatgtagtga
    28501 agtttttctt ttttatttgg atcttctctc acagtagtta ctggtttcat tagtgggcca
    28561 gctttcggta tagaagcagc taaacctgca tagatgatga tcgcaattaa taatgggaac
    28621 aaaacgagga tcaaatgtcg tttcgttaat ttcatttttt cacctcttgt attcgattgg
    28681 ttctaatgtt atcaaaaatt ttatcaaaaa ggtagtcttt atgaaaaaag aaaacaatta
    28741 ttttcctaat tttataaaga aaaagagaat aagctgcaag cctttcaggc tgagggctta
    28801 tcctcttttc gactaatcta cataatacat gattgcaaac gcgtctttac cagtatgcgt
    28861 agcgataacc ggattcgtat gcagtacagg gatatgcatg tccgggaata attcttgcaa
    28921 accctctttg aattcttgcg ccaattcttt tgcatccgca tgtgaaatac cgatttgtcg
    28981 cacatttggc aattctttca gttcattttt caaattatta aaccatttat cgaacgtttt
    29041 ctttcctcgc cccttagtta cagggattaa ttcagaatgg gcgaaattca tcaccacgcg
    29101 tatgttcaaa acactagaca gcaaaccagt tgttcggctg attcttccac cttttaccaa
    29161 gttatctagt gtggatattc cgatgtataa ttttgtattg tcttgtactt ttttgacttc
    29221 ttcaaggatt ttctctactg ttttaccttc ttttgctaat tcagctgctc gaattacctg
    29281 aaaagataat ccttggtcag tggtatcact gtcgataacc gttactttcg tttttgttag
    29341 attactggct tgtcttgctg cttctactgt tccactcaag ccttttgtca tatggatcga
    29401 aatcacttca ctgccgtctt ctcctagctc atcatacatc gagatgaatt ctccaattgg
    29461 tggttggctt gttttgggca gattttttgc tttcgccatc atttccataa atctttcgcc
    29521 gtctagttgg tcatcatcgg gatatactgt tccgtcgatc atgatggata gcggcatgac
    29581 acgaatgcct aaagcatcgc gtacattttt ttccatcgta catgaagaat ctgttacgat
    29641 ttttacattt gtcattattt tctctctctc tttctttaac aagatgcctt attcatgtta
    29701 aactacatgt aagacaattt ctatttttag tataacagac aaataatgat ttttcattaa
    29761 ttacacctag taaaggagcc gttttcatgg aaaaaacgaa atttaatcga acgtatgaaa
    29821 tattaaatga agtgtttaat gcagtcaccc atggaattgg gactggattg agtatcgcgg
    29881 gactagtggt tcttttagta aaaggtgccc acttgcattc ctccctccat attgtctctt
    29941 atgctatcta tggatcgatg atgattcttt tatttttaac gtctactttg tttcattcat
    30001 tgatttttac aaaagcaaaa aaggtgttcc aagtattcga tcatagttcg atttttcttt
    30061 tgattgcagg aagttatact cctttttgtt tgctgagtat ccgaggatgg ctaggttgga
    30121 ctttatttgt attaatctgg ttgtttgcga ttcttggcat tatatataaa gcgttgacgt
    30181 tgcataaacg ggagagagta tcaaaagtat ctacgatcat ctatattttt atggggtggc
    30241 tctgtgtcgt ggctgctgtt cctctttatc actctcttgg aatgactggt gttattttga
    30301 tggtagcagg cgggctttct tacacgatag gcgcattctt ttatagcttg aattctatcc
    30361 gctatatgca tgttgtttgg catttgtttg ttatgttagg tgcaggtttt atgtacttct
    30421 ctgttttatt ctttacttaa taaaaaaaat aaagctatgg atgggacagc tctaaataac
    30481 agctagtcta tccatagctt ttttatatcg tcaattcgcc tgtcccgctt tttacaggat
    30541 tctcattacg ctgatacgtt tcaaattgat gcggataacg atttttttca tccatttctc
    30601 cttgactagt attgatcagt gaccaatcag accagtcaac aggtggaaaa taagcatctc
    30661 catcgaatac atgatggatg actgtacggt ataatatcgt acaaaatggc agaaattctt
    30721 gataaacagc tgaccctcca gcgatgaaaa agataccgtc tgtttctttt tccagagcaa
    30781 gcacgtcttc cacactatgc atgacatgca cgccttctgc tttataggaa gaatctctcg
    30841 tcaaaacaat cgtctgacga ttcggcaacg gacggctacc catcccttcg aatgtttttc
    30901 gtcccatcac tagtgtattt gcttctgtca tttgtttgaa gaatttcaga tcatttggca
    30961 aacgccaagg aagacggtct tcttttccaa tcaatccgtt ttcatcctgt gcccaaattg
    31021 cagctaacat tttctcatcc tttctgattc taaacagcga taggagcttt gatcgccgga
    31081 tgtgggtcat atccttctaa ttggatatct tccatctcaa aatcaaatac tgactgcttt
    31141 tcctgattca aaactaaagt cggaaatgcg cgtatttctc ggctcaattg ttctttcatt
    31201 tgttcgatat gattgatata aagatgagca tctcctaatg tgtgaacaaa ttcgccaacc
    31261 gctaaacctg tttcatgtgc aattaggtga gtcagcaacg cataacttgc aatgttgaac
    31321 ggaacgccta gaaacacatc cccactgcgt tgatacaatt ggcagcttag ccgtccctct
    31381 tgaacataaa attgaaacat cgtatgacaa ggaggcaaag ccatgctagg aacatcttcc
    31441 ggattccatg cagaaacgat caatcttcta gaatcaggag tctttttgat tgcttcgatc
    31501 acttgtttga tttgatcgat aaagccaccg tcttttgttt cccagtgacg ccattgatag
    31561 ccgtagatgt gtccaagatc gccgtatgtt tcagcaaagg aatcatcggt taggatcttc
    31621 tcgcaaaaaa gcttgctctg ctttttatat tcttcattga attcaggatc tgtcaaacat
    31681 ctatggccaa aatcagtcat atctggtcca ttatagtctg gacttttgat gtagcgttca
    31741 aatgcccatt catcccaaat atggttttta ttttgtaata gatagcggat attcgtatct
    31801 ccttttaaaa accaaagcaa ttcgcttttg atcaatccaa aaggtactcg tttcgttgtt
    31861 aacaaaggaa accctttttg cagatcaaac cgcatttggt atccgaataa gcttaatgtg
    31921 cctgtgcctg ttctgtcttc tttacgatgc ccttcttcca acaattttct tcctaagtca
    31981 agatacgctt gttccatcct ttttcctcct aatcttctac ccattcactc aagtattccc
    32041 accgtgccat tttttcttca agttgtgctt ctgtttcaga tacgtcgttt tgcaattctt
    32101 gtaatcgagt gaaattatct ccttgatgat tcatctcttc ttggagcaat gagatttttt
    32161 cttcaagttc tgcaatctca tcttcaatcg tttcccattc tttttgttcc atgtaagata
    32221 atttcttctt ttcagcaggt tccttgctct gtatttttgg tttcgctttt tcagcaggct
    32281 gctgggtctc tttttgcttc agtaaataac tggacatgtt tccgtaataa agttcttgtt
    32341 ttccgtttcc ttggaatact aataacttat ctgctacctt gtccaagaaa taacggtcat
    32401 gggaaacagt gatcacagca cctggaaaac ttctaaaata atcttccaaa atcgtcaatg
    32461 ttgctatgtc caaatcattg gtcggttcat ccaataataa aacattaggt tgctgaatca
    32521 gcagtttcaa caaaaataac cggcgttttt ctccgcctga aagtttgcct atcagtgtcc
    32581 catgcataaa tcttggaaat aaaaatcgtt caagtaattc tgctactccg atttgactgc
    32641 catctgctgt ttttgcttct tcagcagctt cttgtaagta agcaatcatc cgtttatctg
    32701 gtgccatttc ttcattttct tgtgtataat acgcaagatg aaccgtttca ccgatagaca
    32761 ttgtaccgct atccagggga attctgccag ctagaatatt aagcaatgtc gattttcccg
    32821 caccattttt accagtaata cctagtcttt cccgagattg aatcaataaa tctaaatgtt
    32881 ctagcagtgt ttggtcattt atacggtaac tgccatcttt gatttccagt acttttttcc
    32941 ctaaacgttg tgtcgctagg ttcagctcta aatcatcttc ttggtttact tggtacaagt
    33001 tctcctttag atcttcgaaa cggttgatcc gtgcttgctg cttggtgcca cgtgcctgta
    33061 cgccagccct catccaagct aattcctgtt tataaagccg cttgcgcttt tcttcttgtt
    33121 ctacttctac acgatcacgt tctgcttttt ctaagacgta agcttcataa tttcctttat
    33181 actcgtataa ttttccaaat gaaagttcga agattcggtt tgctactcta tctagaaaat
    33241 aacgatcgtg ggtaaccatc aatagtgcgc cacggtattg tttcaaatag ttttccaacc
    33301 actcgatcgc ttcataatct aaatggtttg ttggttcgtc tagtaatagt aaatcgggtt
    33361 catcaatcaa cacttgcgcc agactaactc gttttttctg accacctgat aaagtactga
    33421 tttttttatc taattcactg attcctaatt tttgcaaaat aatctttgcg ttggtatctg
    33481 tagtccaagc atcttcttta ttcatttgtt cttctgcttt agcataacgt ttttgcacat
    33541 cagggtcttc tccgttttcc cctagttcga tcaatgcttc ctcatatgct cgaacagttt
    33601 ggatcaaggg gctgtttcct tgaaagactg cttggagaac agttaattca tcggaaaatt
    33661 cagctgcttg agaaagataa ccaatacggt aatcagttgg ataaaacact gtttgccgat
    33721 caccgtcgct gctatcgata ccggcaataa tatttaagag acttgtttta cccgtcccgt
    33781 tcgtcccaat caacccgata cggtcttttt cgtggaccaa aaaagaaatc tggtcaaaca
    33841 aatctttttc accataagtt tttttgaggt cagttacttt taattctttc aacatgttcc
    33901 ctccttatct tggatattgt atcataaaaa tagtgaactt caggaaaatt tttttggtat
    33961 ttgttctttt tgtgttctca aaaaaagaac aggaccgatt cgatcctgtt ctgatatgtt
    34021 ttgtttttta taaaacttga aaatttttac ctttttattt tattggactc gttttttttg
    34081 actttgctcg aaacgcaaat cggaaagaaa agttatcaga tggtttgttc atcgtataag
    34141 attctaacaa attgatattc ctgcgatagc tgttcgcaga aaacgtcgtg attttttcag
    34201 caacttcgta ttcatcaatg atttttcttt caagataata acctcttagc atttttttcg
    34261 taaacagact atcttgctgg atcatccacg aagaaatcaa attccccgag ttcattttta
    34321 ttccttcaag tttgcgttgc tggataaaaa attgaaccat cgtttcatca taaatatcag
    34381 tcaagttatc taaactttca ataatcaact gagtattttt ttgatatgtc tctctgattt
    34441 cttggatatc ttcatcacta ataaatgtct gacgatcagc atatcttctt tgccaaaaca
    34501 ttttcggatg gagaacgatt cgcattaacc tacggacaac aatgaaccaa aagccgataa
    34561 aagacaaaat ctggcttgtg atagaatgtt cgaatcgaga aagaaaacgg gagtaaaaac
    34621 gataaccatt agaagaaagc ttgcccgaac gataactttc atccaatcca tcccgttcga
    34681 tcgacaaaat cagtgcttgt atttcttgta cttcttgctt ttcatcatcg gttaaatctt
    34741 ccaagtacag atcacgtatc cgttcttgat aattttctat cactgcttca gtggctaaaa
    34801 attcttttgt attacgatca atttccttta tttcttttcg caaaacttca acgacctctt
    34861 ctaaaatcat caaagcattc aaatccgtgc ttttcgcttc ctctgtttcc gtcagcatag
    34921 gcaagacaat gatccctatg accaaagtca ctaagatgac acccgccgtc agaaacaaaa
    34981 gcaaagaccg ctggtaaaac atcatattat tgattgaaaa tggcaaaata aaaatcgtag
    35041 ccaaactgac tgttcccttt acaccgccaa atgttaagat caagatctcg ttcaactgtt
    35101 ttttgaactt tttactgcca tctttgaata cataaaaaag actgatagaa atgaatctga
    35161 tcacaaaaag catgacagag attaatacga taatcgctaa taaaagaccg tttggatata
    35221 aaccgtctcc ccatactggc gagaacactt gcgtcaattc gattcctaaa aatataaata
    35281 ctaatgcatt cagtgtaaaa gcaatagttg tccatgtact gtgggacaag ctcgacaatt
    35341 ctgcatcaaa cacagagatt ttcctaaaac cagaagcttg gagaatacct gctgccactg
    35401 cagcaatgat tccagataca tcaaatgcct ctgccaatac ataggctaga aaaggaagca
    35461 aaagttcgat cagcagatac cctgtgacat cttgtgctga tgctttttcg atcaaatgaa
    35521 ttattttttg tttgaaccag acaagcaaaa agccgatcaa agctccccca atactagaaa
    35581 ctactagact catccccgcg tttactgctg aaaaagatcc ggtgatcagc gcaccaagag
    35641 caaactggaa ggcagtaaca ccagatgcat cattcaaaag accttctcct tccaaaatat
    35701 gcatcgcctt tttagggata ttcactcgtc cagaaagaga actgactgct accgcatctg
    35761 tcggacctaa cgctgctcca aaagcaaagc aggcagcaag tgggacactt ggcaacagga
    35821 atgataacgt cgcacctacc ccgacaaggg tcaaaatgac tcctccaaat gccaagaaca
    35881 aaattgtccc gaaatttttg agaatcgaag aaatatctgc tttttctcct tctctaaata
    35941 acaatggtgc aataatcata actaagaaca attcaggttc aaaatcgatt gattgtcccc
    36001 actctgtcag acctaatacc actccaagga aaatttggat cagtggagct ggaatcattg
    36061 gcaaaatgcg gctagctatg ttcgataagg tgatcgttac tgcaaataca ataactaact
    36121 cagcaaattc catcgtccat cccctttatt ttttattttg tgtaagcatt tttaaaaatt
    36181 gttctttttt ctttaaaatt ttggtttcga ctacttcaac ctgtgtttgg ttcccctcta
    36241 attcacactg tacacgtttt gactccaaac gaagcagatc atgtttcaga cgttccaact
    36301 gacgatacat caatatattt cttttacgca acttacaaag tatttgacgg cggtcatcca
    36361 tcgaaagggc gccatagcga tcatgcaaca gttttttttg ttgttcaaaa ctctctctca
    36421 ttttccagat ctcctataca caaacttcca tcattatagc aaagttcttt ttggatgaaa
    36481 aatatttcat tgtttcatcg tttattgcta gttagaaatt tccataaatt tttcaacgcc
    36541 tcattctatt ccaaatagta tcagatatca agtaaaactt aagaaagata aaagtttctg
    36601 acaaaaggat gtttactttc ccattcctgc ctttcttgtt cttttatcac aacaaaaaaa
    36661 tggggctgcg acaaaaatct tgtcacagtc ccttattctg aataaacggt gtggaagaga
    36721 cagcctatca gtagtaataa gacacatctc tttcacagcc tcatttttgc gtaaaaatcg
    36781 atttattcga aaaattcccc gtatacatct tctacacgtt gatctggatt gatcacgata
    36841 tacaagttac ctgttttttc gctgattttt gttgattgat attgattgtc taatccttct
    36901 gttcctttat ctagatatgg gaagtacaca agatcaggtg tgccatttcg gtaaaggatt
    36961 tccattcgct cgatatcttc gtatttcaat gcgcgattaa acatgcccat ttccagtccg
    37021 cctaggttga tatcatgtgt cgcaactgcg tccccttcat ggaagatttc gattttaaat
    37081 ccagcacacg gatggatttc aacaaattca ctgccattga ttcgtccaaa acttgttgtg
    37141 atttgtttga tccaaagatc gccgatatga cggcggttga tcgtccaggt ttctccattt
    37201 ctaaaataaa attttagcgc tgtcatttct ttactcatta aaaagactcc tttatgatgt
    37261 aatttattct tgtactacct cagtttagca caaatttatg taagtggtca catcttatgt
    37321 tttttcttct aatgacgtat ctgcccactt taagtagcca acaaagctga gcagatacag
    37381 tctagtgttt tttaaatcaa tttttctttc gataaaaaat ccaaaacctg ttttttatca
    37441 ttttttattc tttgttctac gacggctttt tcagctaatt gcaaagcttc actaacccac
    37501 ttaccaggtt tttttccagt ttcttctagc aagattttac catctactgc taattcgctt
    37561 aatgacttga taggtaaacg atcataggat tctcctacgg catccatctg aggtgtttcg
    37621 tcaaaataga tcatcaattc ttctacttgc agtgcatgtt ttttgcctaa gaagtacaat
    37681 tcgaatggtt ccaaagctcc agtttctcgt tgtcgtagtc cttggacaag tgcttgaacg
    37741 tctttaatca tttggttaga acacttccac gatttcaaaa aggaacgaat ctcattttct
    37801 tttagatcca gttggctgat caataatgcc catgcttggc tctcttcttt caatgggacg
    37861 gatggtaatt cagcaaaacg taaaagtgct tcgccttctt ctttcaaacc gggacagcaa
    37921 atgtagcact ctgtttcaat aaatgcatgg attcccgcgg cccgttcatt tcccaagagc
    37981 atcttgatga attccacatt tatacgttct acagatattt tacctaatag ctcgtggttt
    38041 tctttgatgg cgtagaaggt ttcttcctct aatttgaacc ctagttgact gacaaaacgc
    38101 aacccgcgca tcattcgtaa ggcatcttca tggaaccgct catgaggatt gcctacagct
    38161 cgcaagatct gttcttctag atcttgcaga ccatcgaaca aatcgatgat ttctccatct
    38221 tctttcaaag caaacgcatt gatcgtaaaa tctcttcttt tcaaatcttc tgccaacgaa
    38281 cgaacgaatt cgacatgatc tggtctacgg tagtcctgat aagttgattc cgtccgaaat
    38341 gtggtgatct catattgttc atcattttct aataccaaca cagttccatg ttcgatccca
    38401 atatctatcg tttttggaaa aagctgtttg atttcttctg gaaatgcgct tgttgcgata
    38461 tccacatcat ggattggctg gttcagcaag atatcacgaa cacttccacc tacaaaataa
    38521 gcttcatatc ctgcattctc taattttttc agaactggaa ttgccttttg gtattccaga
    38581 ggtaattgtt ttaatttcat ttttccaacc tttcctgcgt gtttcttgtc ctgagataaa
    38641 gactcagttg catggtgact gtttgacaag tccgtttcag agtcttcaag gccaggacca
    38701 cttcatcttg tttactcgtc cttacgctca aagcgattat ggtctctttg attgaatttt
    38761 tccatgtttt tttcaaaaac ttcagttaag tcgatattca atgaattagc catgatcatc
    38821 gtaacgaata aaacatcacc aagttcttct gctaccgagt taactggttc agaagccttt
    38881 ttgctttttt ctccataagt gtggttgact tctcttgcca attcacctac ttcttcagtt
    38941 aatcgagcca tctgagctaa tggagagaaa taccccacct tgaattgctg gatatattca
    39001 tccacttcct gctgcatact gtataaagaa cgctttttat ccatcttttt ccctccaaaa
    39061 ctatcttacc aaaactttaa cgcaaatcct agataagagc aattgagaaa atcgaatttc
    39121 catgctacat ttaggaagga atttctaaat ggaaattctg tgaaaataca taattgaaag
    39181 ctggaattca tatggtcaaa cgaaaaacag taaaagaagt tctttttatc attataggaa
    39241 caagtattta tgcatttggt cttgtttact tgaacatcgc taatcattta gcagaagggg
    39301 gagtctcagg gatcaccttg atcttaagag ctttatttgg tattgatcca gcttatacga
    39361 ctttattaat caacatccca ttgattttac taggaggaaa gatcctcggt aaacgttcct
    39421 tggcctatac tgttctaggt acactttctt tgtcattctt tttatggatc tggcaaaggg
    39481 ttccactaga aatcaattta cagcatgatc tactgatcgt ttctctactt gcgggtttag
    39541 ttgcaggtgt aggaagcggg atcgtctacc gcatgggtgg aacaacaggc ggcagtgata
    39601 ttatcgctcg gattttagaa caaaattacg gcatcactat ggggcgttcc ctattggcat
    39661 ttgatatcat cgtcttactt gcttcattaa cctatatcga cttgaaacgt atgatgtata
    39721 cgttgattgt ttcgtatgtt ttcagtcgtg tgattgattc gatcttagat ggcggatatt
    39781 ctgcaaaagg tctacttgtc gtctccaaca aaagcgaaga gattgcacca ctactgatga
    39841 ccggtctgca aagaggtgtg actttccttt ctggagaagg cgcattctct ggtaattcaa
    39901 aaaaaatcat ctatatggtc gttagctcta gtgaattaac tgaagctaag aggatcgtcc
    39961 acgagattga cgaaaaagct ttcctttcaa tcatcaatgt gcatgaagtg gaagggcaag
    40021 gctttactta tttgaagcca cagacaagat tactgaaaaa actataagaa aaaagacaaa
    40081 gataggctat gaggaaagat tccacatcca gctgaccttt gtctttttta gtactatact
    40141 atttttaact aattgttatg ttcacttacc cggttacttt tcttttgtgt ctgcaaaagg
    40201 atctttcggt taacttcatc agataatttc aaaaaagcat ccctatctcc atcttctagt
    40261 gcttgatcga tttgagcata aagcattttt agttttgcct cttcttcttt ttcttgaaaa
    40321 tatcgttcaa ttaattcagt atcttcttca ctgactgaag aatcccaaga agaaaatgga
    40381 ttgtcttcta agatagatag atattctctt gtctgccaag cattttcgaa tatacattcc
    40441 acatataaag gctttttcca attcaaacgg atttcatgaa aaatctggtc tgtgtccgta
    40501 aattcttttc cctgcaaaaa caatttcatg ggttcccctt caacagatag atcactgatc
    40561 tgcagtcctc gatccgcaaa attcgcccct tcaacaaagt ggacattgct taaaatcgct
    40621 tcatgattgg caagataatt caagatccaa aaaacttctc ttcggctaaa agatacatga
    40681 ttgaccatcc acgttaaaaa attcttcttt tcccgtacat caattagcat ttttctcacc
    40741 tctctgttag gtcatctaat aatgacagtg cctccatatc tcctggttca agtgttaaat
    40801 aataagtcaa taattcttgc gctcttttca gctgcccttc ttctcttaag aaaaaggcat
    40861 actctttcaa gaaatctggt tcatgtgata gttcatgata agcctgttca tagtgtacag
    40921 ctgcaacggt aaagtcttct aattcattat aagcatgggc taggttccat tctgcataag
    40981 gattagcagt ttcttccatc tgattgatca cttgtatcac atcttcatat ctttcatcat
    41041 ccaagtaaag attacttaaa gtaagtaatg tttcatcttg tttgtctcct acttctaaag
    41101 ctttcagtaa aagttcttct gctcgctgtc tatcatgcag acggaaagca ttttccgagg
    41161 ccaggtgata aagttcgact tggtaaggat tttctttgat tccttcttct aacactgttt
    41221 gtgcttcttc aatcatttct tcttcttgaa gagcttgtcc tagatataga tataacgatt
    41281 gataatgcgg attaacttct cgaagttctt ccagatagtt gattgcctgc tgattttctt
    41341 tcaattgaag attcgtaaaa gctagctgga acagtcgatc atctgtcctt tcttctttca
    41401 gtgcttcttc taaaggtacg atagctgctt cgaattctcc ttgcatactt aaggattgtc
    41461 ctaaacgttc ctgcatcgag attcctgaaa tttcatttat cccgcttgcc aacaatgttt
    41521 cataaaccac tgctgcctct ttgaaacgat caactgaaaa atacaattca gctagcgcaa
    41581 actggatcaa tggttcatca ggaagcaacc cagctgcttc tttcaatttt gcttcactca
    41641 cttcagggat tccgataact tggtacaaat cagctatcgc caataagctt tgcggatagt
    41701 aatcactttg cttatccact ttttccaggt attcaaaagc taagtcgatc tcattatctt
    41761 cgattgcaat ttctgctaac gggatgttca gtccgtcatt ttctgggtat tggttgatca
    41821 gttgttcaaa aatctgtttt gcttcgatca aaaagccaat agccagcaat tcttcgccta
    41881 gttcagctaa tatatctgct gggtcttctt ttaatgcttt ttctaaaaag atttgtgctt
    41941 gtgacaagtc ttcatctgat aaagcttgca acattttttc gctatttgta ttcatttcaa
    42001 ttccctctta tctcactgac gatttgttga aataccgtca ttgttctcaa taattctttt
    42061 tcgtttggat gttggtatcc gtctattata cctatttttt ctaaaacaag tatttttttg
    42121 cttttttctg ccaaaaaaag aactttttcc aaatactcca tctttgaaat ctgttccagc
    42181 cagtggattg gatagccaag caagtccagc cacacaaaaa agttttttag ttggaaatca
    42241 aaaggatatg cttggagatt ccacacgaaa tgaaacatca ttcctaaaaa ttttttcata
    42301 ctagcagaaa gtagatggcc attttcggtc agataaaaag cttgttcaaa cagtttacca
    42361 taatttgaca ggttttctgc ctctaattga taaaaataga tcatttcttc gatcatcccg
    42421 gcaaacggcc gagtcgttaa ttgcttttta tttggatagt ttttatacag attttgcaaa
    42481 aaacgatgat cacaaatcat tccgcaacag ataaaagtca aaaagtcaat ctgctttccg
    42541 tccacctgcc gctcgctgat tgtttgatca taaacgatgc gttctggcag attgatggtt
    42601 tgcagcacta cacgatttgg tagctgcaaa atcgtccgct gcggtgttaa tgctcggctt
    42661 agagaacgga tcgatacagg gatcatccat agtgatgaat caagggttgt atgtttttga
    42721 aaaaaacctg ccagatccat gatcccttca tttccaaatc cgatgataaa catggattga
    42781 ttttcgggat agcgtttgac gaaatcaagc aggttcttta attctgttaa atgattgcat
    42841 tgagtgttgg cacaaatata ccagtcattg tttgcttgat ttgcaaataa cgggttgatc
    42901 ttatctgcaa acaaatcata atagcgctga ttcgttaaaa ataagattgg ctgatcaatg
    42961 gaaagttctc ttagctgact gactagcgtt tctccgtaaa acactttcgt caacgcatct
    43021 tctacttgat aatcaagttc catacgcatc cctcctcttc ttatttttat tttaccatta
    43081 gtaagcaaat tctagaaaag ataagagcaa agctcacctc ataacttgca aataaataaa
    43141 aattaaataa aatacatgtg ttttctatgt atgacatacg gattcggaat ctctgtctct
    43201 tatttattcc ttttctgcta ggaaataaaa agaaaagcac ttgtagccct agagccacaa
    43261 gcgctttttc aactgtctta tttaacagcg tcttttaatg ctttacctgg tttgaatgca
    43321 ggtactttgc tagctggaat ttcgatttct tcaccagttt gtgggttacg acctttgcga
    43381 gctgcgcgtt cgcgaacttc aaagttacca aaaccgatta attgaacttt ttcgccgtta
    43441 gctaaagcat cttgaatagt tgaaaataca gcatctactg ctgcagttgc atctttttta
    43501 gttaaatcag tagctgaagc aactttttcg attaattctg ctttgtttgc catggataga
    43561 ttcacctcct ccacaagaga tatgatagaa atatcattta gttaaaactt tctgagtggt
    43621 ccagaagttt aaaaagaaat attgattaac ttcaatattc tgttatcacg atatcatatg
    43681 aaccgcttaa tagcaaggtt tttaccaatt ttcacatgct ttttttagtc atagaaacgt
    43741 aacaaacgaa actgtctttt tcttttgaaa aaaaaacgtc gatatggtaa aatgcctatt
    43801 ttctcctacg agggataatt cggatggacg tcccttcaaa agtaaatgct tttctgattt
    43861 gattttctaa gaaacgttca taagaaaaat gcatcaattc ctcttcattg acaaaaacga
    43921 caaatgtagg tggtttgaca gcgacttgtg tagcataaaa aatcttcagg cgttttcctt
    43981 tatctgttgg tgttggattg attgctacag catccataat gatatcattc aacacagccg
    44041 aagagatacg aagattctgg ttcatactta cttgttcgat catttcaggc agacgttcca
    44101 accgttgttt agtcactgca gaaacaaaaa cgattggagc gtaatcaaga taccggaatt
    44161 catcacgaat ctcttgttcg aaatcacgca ttgtattggt ttctttcttt acaagatccc
    44221 atttattcac gacgataata attccacgac cagcttcatg ggcgtaaccc gctactcgct
    44281 tgtcttgttc ccgaatccct tcttcagcat tcagtaccat caaaacgata tcagaacggt
    44341 caatggcacg cattgcacgc atcacgctgt atttttcagt attttcgtat acttttccgc
    44401 gtttacgcat accagctgta tctatcatta agaatttctg accactttca gaaacgaagt
    44461 gggtgtcgat tgcgtctcgg gtcgttcctt caatatccga aacaattaca cgttcttctc
    44521 ctaaaatcgc attgatcaaa gaggatttac caacatttgg gcgaccaatc aaactaaact
    44581 taatcgtgtc gtcgtcctct tcttcagtct cttcagagaa atacttcact gcttcatcta
    44641 aaatatcacc aatccctagt ccatggcttc ctgaaacagg ataaggatcg cctagcccta
    44701 aggaataaaa ttcatagata tcgtttctca tttctggatt atctacttta ttgactgcta
    44761 aaatcactgg tttattactt ctgtataaaa ttttcgcaac catctcatct gcgtctgtca
    44821 cgccttcgcg tccgctgact acacaaatga ttacatctgc ttcttcaatc gcgatttctg
    44881 cttgatgctt gatctgatcc ataaaaggtt catcgccaag atcaattccg cctgtgtcga
    44941 tcacgctgaa ttctcgacct aaccattcac cttttgcata aatacgatca cgagttactc
    45001 caggagtatc ttcgacaatc gagatacgct caccagcgat gcggttaaaa atcgtagact
    45061 taccgacgtt cgggcggcca acgattgcaa ttgttggatt tgccatatta tttcctcctc
    45121 acaagtttcc aatctcactt agtttaacga atgcattgcc aactttcaag catagattgt
    45181 caattaaacg aagtattttt attccttatt gaaatactaa tcgcttttca aaagaaaaac
    45241 tgagacaaaa gcagctgctt tcatctcagt cacagataca aaatcaatta tttttcagaa
    45301 tcatcggttg ctttttcttc tacttcttct ttcaacgcat cacctaaaat gtctcccata
    45361 gtaaatccag tattttcttc tggtaattca taagactcaa cattttttgg ttcttcttct
    45421 gaagctggtt tttcttctaa agctttgata ctcaatgcaa tacgatgttc ttctggatgg
    45481 atctctaata ctttcacttt cacttcgtca ccttcatgaa gcacttcatg tggtgtcgca
    45541 atatgtttat gtgaaatttg agagatatgg actagccctt ctactccagg gaacacttca
    45601 acaaaggcac cgaagcttgt caaacgttta actgttccgt ctaatactgt gccaactgga
    45661 gcttttgtat cgatttctga ccaaggtcca ggctgtgtgt ctttgattga caaggaaaca
    45721 cgttcttgtt caggattgat agacaacact ttgacattta catcatcatt gacagccaat
    45781 acatcacttg gttttgctac atgactatgt gaaatctctg agacatggac tagaccgtca
    45841 attccgccta ggtcgacaaa tgcgccaaaa tcagtaagac gtgcaacacg tccactgaga
    45901 acatctccct catggatagt tgaaagaatt tcttttttct tttcttctct ttcgttttcc
    45961 actaccgctt tatgcgataa gatcaaacga ttttctgatg gttcgatttc gatgatttta
    46021 aagctcaatg ttttgccttt atagtctgaa aagtctgcaa caaaatgatc ttccaccatt
    46081 gatgcaggga caaaaccacg tacaccgacg tcaacgacta aaccgccttt gacaacattt
    46141 gtaacaggtg cttcgatgac cttgccctct tggaaatctc tttcgatatc ttcccaaact
    46201 tttttagcat ctaaacggcg ttttgaaagt agatagctgc cgttttcttt atctttgccg
    46261 atcgtactga taacgactaa atctaataca tcaccgactt ttactacttc gctgatatct
    46321 tctaccggca aagttgataa ttcttttgcc ggaacgactc cttcaactcc agccccttcg
    46381 attccgacaa tcacttgttt gtcttcaatg actaaaactt cgcccttaac aacatcgcca
    46441 acttttactt cttgtacgct tttcattgcg tcttccattg actggttgtt ctcttgattt
    46501 tgatcaaatt ctgtcataac acttgtcctc ctaaccaaca ttctgccgta agtacggtac
    46561 tgtttttagt ttaattgatt attcaaaaaa aataaagcga tttcgttcgt tttccttgaa
    46621 aaaacaattg tttttcattt tttttcttaa tttaaaaaag aagataacct tttttcaaaa
    46681 caacagcttt tattgctgca acgacttctg gaatcgattt gccagtcgta tcgatacgaa
    46741 cagcatcctc tgcttgcttc agcggagaga cgtcccttgt tgaatcataa tggtctcttt
    46801 cctgtatctc tttcgtcagt gtttcaagat cagtcggaat tcctttttct tggttctctt
    46861 tgaaacgtct ttctgcacgc tcacttacgc ttgctactaa aaagattttc acttctgcat
    46921 tcggtaatac agctgtcccg atgtctcttc cgtccatgac aacgccaccg cgttccccta
    46981 tttttcgttg gacagcaact aattcttctc tgacttttcc atgtgcagag acttcagaaa
    47041 cagcttttgt gacatctggt tgacggattt ctaaagtcac atcttttgat gctatgaata
    47101 catgctgtcc atcttcttgt tgcgaaaaag agataggata ctttttgatc agcgaaacta
    47161 gcccttcttc atctgaaaaa gatacattgt tcgtaatagc taaataagtt actgcgcgat
    47221 acatggcacc ggtatctgta taaatataat tcaattcttt tgctaatatc ttggcaacgg
    47281 tacttttccc agatgaagca ggcccgtcga ttgcaatact gatttgtgtc atgatataac
    47341 tcctttttct cagaaaaaaa gccgcaaagc gcggctatta ttatttaatt cttaattctt
    47401 gaccagggta aagcataaag ttgtttggat ctaagccatt caattcaaac aattgatcag
    47461 tggtgatccc tgcacgctca gccacttgtt ttggaccttc gcctgcttga acagtcgttg
    47521 ttgaaccggc tgcagctgat gaagaaggtg ttgtttctgc tgcattgctg cttgaatccc
    47581 ctgcttgata agttgcctca cttgaggaag tcggtgttgt ctctgctgca atactgcttt
    47641 ctgacgttac acctgtatct tgagacacag tagattcttc cgcgattgta ctagattcta
    47701 ctgttgaagt ctcagttgac tcctcttttg ttgtacttgt agaactttct actactgatg
    47761 tcgaagtttc agaagaagtt gctgctgttg cattgttgct tgatccattt ctgatccaga
    47821 aataagcacc tgctggaata gcgatacata agaccagtaa aatcaaaaat agcgaaagaa
    47881 ataatgtatt tcctttcttt tgttgtctct gagaacttct tgatgaaact tcatcatctg
    47941 tatcgtagat tggttgttcc catggttctt gtgtttcgtt attttctgta gattgatgtc
    48001 tatcttttct gctcactgtt ttacctccta aactctatcg tgtgtattat accataggaa
    48061 aaagtgtctt gtcctaaaaa atcaatgttc catgtttttt ttaaataaat ttagtaaaat
    48121 cgtttcccaa tgaagttgtt cagtcttaga aaaaagcttc ctctttggca gaagttctgc
    48181 ttttgctcca tcaatatcac aacaattctg cggcttttcg gagagttttt cgccaaaata
    48241 agctaagatg aattttctgc ggcagttttc ttcattaata tagcgaagca tctgctgcag
    48301 gcggaattct ttttcttttt cctgacgttt gagccgttcc acccaatttt ctggtttttc
    48361 agactgctgg atcagctcca tccatttttt ttgcagctca tcaaagggag cttgctttgt
    48421 ggcatattcc aaataaagct caaaactttg tcgctgttct ctagaaagtt gattaaagaa
    48481 ataatggata cgttcatccc cactttgata aaaaagaatt gctgcacttt cttcctgatc
    48541 tctgcctgct cgaccgattt cttgtacata gttttctaga ctgtctggca aatcataatg
    48601 gaccacataa cggatatcag atttatcgat ccccatacca aatgcattcg tagcaatgag
    48661 aaactgcagc tgatttttta caaactgctg ttgaagttgt cttctttgag ctgcatcaag
    48721 accaccgtga tagtatccaa ctgtaaaacg ttccctgaat aaatgataca atcgttcgac
    48781 ttcttttttt gttgcacaat aaatgattgc cgctccttgt gctctttcca tgaagtgttc
    48841 aagttcttgt tctttttgct gcgttttccg aacaaaaagc gagatatttt gccgattgac
    48901 tgattgtctg atctcttttg gtggtcgatc aaatagtaca tgacgtatat ctcttgctac
    48961 taaatctgtt gctgtcgccg ttagtgccag tgtgaccggg tttcctaaaa gctttcggat
    49021 ttttcctaac tgttgatatt ctggacggaa atcaactccc cattgagaca cgcaatgagc
    49081 ctcatctact acatataacg caatattttg ttttttcaga tgctctaaaa gagaaggatt
    49141 agtcaacatt tcgggactca aaaacaaaaa tttatattgc gatagatgac ggaggacgta
    49201 tcttctttca gattgcgaaa gtaaactatt gaaagcagct actcgtttct cccctcgttt
    49261 ttgtaattgc gtcacttgat cttccattag agaaagcagc ggtgacacga tgatgaccag
    49321 accttccatt aaataccccg tcaattgata gcaaaggctt tttcccgttc ctgtaggcaa
    49381 aatagcgaga gtatcttctc catcaagcaa cgcctgaata atttcttctt ggccgggacg
    49441 aaatgaatca aatccaaaat atttttttaa ttcatttatt aacattctgt atcgcttcct
    49501 ttctcaatag atagatttga tacaaacgaa attctccata atctaattgt ccatctacat
    49561 tccattcgct aaagcgccac tctcgcacgg aatccttatt tggttccaaa cgttcgattg
    49621 tttctgcaga gagaatccac tcgtatggaa aatcatcaaa aaacaaggcc cactcaataa
    49681 gatgatctgt tactgttcct ctttttaaat gacggattgc catgatctgg tcaattgtct
    49741 gaccattcat aaacatctgc ttggtgatca tcatgctttg attgaaattt tgctgtaata
    49801 atgaatcgat caaagcgtgc caaagcgaat ctggccgttt ttcgatttgt gctaacaaaa
    49861 ggtggataca tctgctttgt tgcagataaa cctctgactc atcattgttt tttgccagct
    49921 gataaggaag cagccctgtt cgctcatttc cagataattg gttagctaaa aaatctgctg
    49981 cttcttctgg tatctccgaa aacagctgca ccaaactctc atacgcagta tcaattaaaa
    50041 tttcacgtgg caattggctt tcactaagcc atttttttag ttggaaagta taaaaaggac
    50101 ttgtctctgc tggaagatag tcttgaatac ccgttgccag attagaaatt acttgaacag
    50161 caaatttaat gagccgccaa ctagtttccc ctgttctgcc atagcggtca aaacgcaaac
    50221 cagtatgttc tatttgatgt tcggacaaca tatcagcccc tgcaggcgtt agctttgctt
    50281 cattttcatt tatttcgatc caaccttgct gcgcaatttt ttgcaaaatt tgataaaact
    50341 tatcctgctt caattctgga aaactgttat ggataaacaa aagttcgtgg gtaaatccat
    50401 aaataagtac tgaagtcgtt cgttttccca caaggagttg gtaaagagaa ctaatccgca
    50461 gcttgtgtcc tgatgaaaat agcgataaaa taaaaacaat catattattc tccttaagtt
    50521 aggatggtta gaaatgtcac tactatgtaa acttgtacct gaacgctgta ttgcatgcgg
    50581 tctttgtcaa atcgaagcgc cagatatttt cgattatgat gaagaaggaa tcgttttatt
    50641 tgcccaagaa ccagaggctc atcaacagtt cgtgatgccg gaagaagaaa catatgtaaa
    50701 aaaagcgtat caaaaatgtc cagttcgagc gattttatta gaaaataaaa tataaatata
    50761 aacgaaactt taaaaacgta cactaagttc tctaaacttg aaaataagcc gggatctgtt
    50821 tctcttgttc cgtgaaatcc cgacttattt tgaaagattc atttgctatc tatagttaat
    50881 tgactagttt tttcacggac cctataggac ccatttatat tatttcaact ttttcagcca
    50941 gttttccaat gtattgacga tcacagtttg ctggtctgcg ttagaaattt ctgcctctcc
    51001 atctcctttt tgctcaccat agctgccaaa acctccatga tttccgccat tgattgatac
    51061 atactctgtt ctttccggta aatactgctt agcttcttga taagcttcct gattcaatac
    51121 tttatctttt gtcgccgtga tcgataaaac aggaacagct gattctgtca atgttccttt
    51181 tttgtcggga taacttgcca tgaagaatac cccttttaaa tgtttgtctg aatgattctt
    51241 attgacataa cgacttgcca ttacgccacc taatgaatgg ccaccgatca cataatcgga
    51301 atttggaaaa tcttctttga ccttatccgc tttgtttccg cccatcactg ctagatcaag
    51361 tggcattttg acaatagcga ctgaaaagcc gttttttgct aaatcttgcg cccaaatact
    51421 ataactttct ggctctacga gagcaccagg ataaaaaata agtaatggag actttccatg
    51481 attctttttc tctccttcaa aaaataagta atcttctttg ttttttcctt cttttaccaa
    51541 cacttgcgct tctgacgatg gttcgtacgt attttgctgt atatagtaat aaccggctcc
    51601 accgagtaat cctaaaatga tgactaagcc aattagtatt cgtctaaata ttttcacttt
    51661 ctcccacctt ttctatctga gtgacccctt tttcttaatc aagtatgatt ataccttaaa
    51721 aaaataagag agaaatgcaa actttccagc atcaaataaa aaaagacgga atatccattt
    51781 gaatatccgc cctttttgta tgtttatttt tatttagcac ataaacgata cacagcttct
    51841 gcataaattt ccattgcttt atacatacta cttaattccc atcgttcatt cgcctggtgc
    51901 ataaagtcag gagtatcagg gaacatcgca ccgaatgcca cacactggtt catcgtacga
    51961 gcaaaagtag cgccgcctga tacaaacggt tcagtcatgt ctccagtaat atcgcgatat
    52021 gtccccaata gatttttcac taactcactg tctagtggca cgtataatga atcaaggaag
    52081 tcaaattctt cataagtcaa cccatatttt tctgctgttt tagttaattt agctactaaa
    52141 tcatctttct tgaatgtaac agggattctc atatctacac cgatttttgt ttgttctggt
    52201 gtgatttcca aacttgcaaa gttcatcgtt agctcgccgg attgttcatc ttctgttttg
    52261 cccacgacag cttcaccagt tgcattttct tgaactaatt ttcctaagaa attgattggg
    52321 ccaaaatcaa atacttctga aagagcaatt gccagacgag aaatagcatt cactccttgt
    52381 gctgcatctt tcgcgtggat acttttacca agaacgacga tgccttcacc ttgttcttcg
    52441 aaatcgaatt cgtgtttttt caatgcttct tttacttcag aaagcttttc tccagagtaa
    52501 ggagctgcat caggaacaac attcaacgct cctccagctt ttacagaaaa ctcgttcgtt
    52561 cctggtcctg tcaagtaagc ttgcaataag cctttttctg cataaattaa aggaaattca
    52621 gcatctggcg caaatccttg cgtaattcct tcttcttttt cgttatattt ttctaaacaa
    52681 cgccataaat tttcttcatc tgtaccaaag ataaaacgaa tacgtgtctt gaattccacg
    52741 ccagcatcaa tcaaagcttt gacggcatac attgccgcaa tagaaggacc tttgtcatct
    52801 tgggatccgc gaccaactaa ccagccgtct tttatagttg gatcgaatgg ttttgtttcc
    52861 caattatttt cgtcccctgc tggaacaacg tccatatgac acaagatacc gaataattca
    52921 tctccagagc caatctctga ataaccgtaa tagccttctg gatctttaaa tgttctaaat
    52981 cctagctttt cactgatttc caatacttta tccaaagctt caatcacttt tttaccgaag
    53041 ggatgtcctt gtcctgaatc tgcttcatct agtacggaag gaattcggat caattcgctc
    53101 aatgattcta atgcttgttc atgatgttgt tctgtcacaa attttttcat gatattatcc
    53161 tcctaatatg ttaaaaaggg tcatgtcaaa ttcctccgac acaacctctt cttctcaaat
    53221 aatgacgttt taagcctgct ccatcagcaa gcagaatgtt cttaacaaat gatgaaagaa
    53281 aaaacactca ctgaatggag ctattgactt atccacgtgc ttatcgatag ccgtttatcg
    53341 gtttcttcat tcttatgata gaccttgtac ctgtatttgt ctaggtttag aacattgctg
    53401 ctacacctag gatcacacag atggctacaa ataatatcgc aattaattta ccggtaaatt
    53461 tccaccacac tgaaacatcg aaacgagcaa ttgctacagc acccattacg atagcagatg
    53521 ttggtgtaat taagtttact aaaccagatg cagattgata agcagtgatt actaaatcct
    53581 taccgacgcc ggcaaattca cccataggtc ccatgattcc cattgttgca gcagctaagc
    53641 cggaagttga aggaatcaag aatgacatag ggatatagaa aataaatgta ataatgatga
    53701 atacacttga agataatgaa cttaatcctt gttcgcccca atgtaagatg gtgtctgtga
    53761 ttaatccatt gttcataacc acttggatac cacgagcaac agctactacg attgctacac
    53821 cgatcaaatc agaagcacca gctaaaaatt cagagacaaa ttcagactct ttcatgccat
    53881 aagtgattgc tactacgatg gacattacta agaataacat agtaatttct gggaagtacc
    53941 agtcacctaa tggaagcatg cttttaccta gaaccgtacc tagtaccgga aggtttgtta
    54001 accagtttgt caatgattca aaaatcgtga aattcgcatt caaggttgtc caaggaatca
    54061 aactgatgat catgatacca aaagtaataa agaacaatac attaacatgt ttttgttttt
    54121 tcgtgattac ttcttgacga ccgattgctt caatatcgaa atgcttcata tcttctttac
    54181 gttggttgta tactaatgat tttgttggat ctttttcgat ctttgatgca taacgataca
    54241 catatacaat agaaatagct aacaaaataa cgaacatcaa gaatcgaaga ccaatacctt
    54301 cacccatcga aatcccaaca gcttgtgaag ctacgcctgt tgcaaaagga tttaccgttg
    54361 aagctagaca gcctacttga gaccctacta atacgattgc tacagctact actgtatcaa
    54421 agcctacagc catcatgact gggatcagta aagcatagaa tggaatcgtt tcttctgcca
    54481 ttccgtaagt agagccgcct aatgcaaata acagcatcaa tactggaata agcatttttt
    54541 cttttccttt gaatttcttc acaactgaag caatcccggc atctagtgcc cctgttttgt
    54601 tgataatacc taaaaatcca ccaacaacca aaatgaagaa agagattggg attgcagcag
    54661 gtgtttcttt agttagctcc cccgctggta cacctagcat cccattgatt ggcgccatga
    54721 aaatatccca cagcccttga ggattttgtt gtactcgttc atatgatcca gcgacgatgt
    54781 tgcctgcatc gtctacacta tagtgcccag ctggtataaa ccaagtaagt acagcgatta
    54841 ctgcaataat aataaataag accgtatacg ctgaaggcat ttgaaatttt ttcttttttg
    54901 tttgttccat cttcttcttc ctttcttttc cgttagagac aacaattttg gctctaatgt
    54961 tattttatca aaaagagtat cagaacaaaa ataataacac gcattttgta aaacttttgt
    55021 tcaaaaagtt cgtttttccc tattccctcc tcttttttca ggtttttaaa gctttcttct
    55081 ttttcattgt agcgtttcct tttttttata aacaaacatt ttcgtctttt aaaaggagaa
    55141 gaatttcaca tttgcaaaga attgattgat ttttatgcat aaatcaaaaa aatactcaaa
    55201 acaaacaaat aaaacgttta cattattgca tgtcttgtat ttttttccaa aaaaaaaaga
    55261 ccaagaaatt tcttgatctt tttgatattt atttgactgc tgtatgacgt tgttcgaact
    55321 gatgttgttt tcgacttaac catggaagaa gttgcgcatg cagcactaaa aagacagcac
    55381 tcacgatgaa tcctttgatc aagttgaaag gaacgatccc aatcagtaca tagtttgcta
    55441 aagacatgcc cagcatctgt gttgcgttca gccctaaaaa cattaagtaa agaggcgtaa
    55501 taacgaaata atttgcgata ctcataaaaa tagttagagc gatggttcct gtaatgacac
    55561 ctaaaaattt gtttcttcct ttatgctgtt tctttacact aaagaaataa taaatcggga
    55621 atgtaaagat cgttgttgat aagaaactag cagtgtctcc taccaaatta tccggagaaa
    55681 aacctgtagt cagcagatgt aatactgaac gcaagaacgc tgttgcaact ccggccgctg
    55741 gaccgaataa gaacatgctg atcaataccg agatatcact aaaatcgatc ttcaaaaaac
    55801 taaaagccgg catgatcgga aaagcaaaat actgtaaaac taatgcgatc gcagcaaaca
    55861 tcgctactgc aaccattttc tgtacacggg tgttcttcat ttgaaatcct cctgttagga
    55921 ctcctcttca gcgaactttt tgacgtttct ctccaaatga aaaaactcta ttttccaggg
    55981 aaaatagagt tagagttatt tgatcaagcg tcgtcaaata agctctatct tctttatcca
    56041 gactatactg tcggtatcgg aatttcaccg attcagctat ttttttgcaa aataggtcgt
    56101 ggactataac caccggtcgg gaatttcacc ctgcccctga agacgaacct tatataattt
    56161 ttgtttacat attcattata catatctatt caaaaaacgc aacatctaac acttataaaa
    56221 agtaagtgtt cattttgagt ggttcagcaa actgctgact tcttttttgt tcagttcacg
    56281 gtaatcccca ggacgtaggc cttgtaaagt cagatctccg tatttttcac gttttagttt
    56341 ttgcacagga agaccaactg cttgaagcat atttttcact tgatgattac gtccttcgtg
    56401 gatcgtcaat tccacgatac tgtggtttgt cttaggatcc actgataaaa tttggaattt
    56461 agctggagat gtttttcgtc cttcgatctt tattcctttt gtcaaaggtg caagcatcga
    56521 ttttgtagcg atccctttta cctttgcaac gtaaacttta tccacttcat gttttggatg
    56581 tgtcaggcgc tgagcaaaat ctccatcatt tgtcagtagc aagatccccg aagtatcgta
    56641 atccagtcga cctacaggat agatacgttc ttttaccatc ggcaaaagat ccgtaacaac
    56701 ttttcttcct ttgtcatctg caacagcaga aataactcct ttaggtttgt acaataaata
    56761 gtaaccgtat tcttcttgat aaattgggac ttcatccact tccacagtgt catgtttccc
    56821 aacttttatc cctaattccc ttacaacttg tccgtttact tttacacgtc ctgcaaggat
    56881 gaattcttct gcttttcgac gagaagtgat gccagcgtgg gcaattactt tctgcaatct
    56941 ctccattaca attattctcc tttattcatt ccatcaaaga atagatctgg tgacacgtct
    57001 tcttcaagtg aaatttccat ttcttgtgta tcaggcagtt cttctaatga tttcaaacca
    57061 aaataatcta agaagtagcc agttgttcca tataatatcg gccgacctgg tccttctact
    57121 ctaccttttt cttcaatcag tttatgggca gctagacgct gtaccgctcc tgaaacctga
    57181 actcctcgaa tctgctcgat ttcagctctt gtgattggct gtttataagc gatgattgct
    57241 aaggtttcga cggcggcttg agataatgtg tttgatgtcc cttgcgcata tcgcttaagt
    57301 aagggagcca gctctttttt agtcgttaat acataatggc tttccgtttc aaaaatatgc
    57361 aaagctgagt gcgagttttg agtgtaagat tcttttaatt ctttcactaa acttgtgact
    57421 tctgcttcgc tgagatttaa cagtccgctt aattcttcat tactgatccc ttcctcgcca
    57481 acaataaaaa gaagggcttc aagttcactt aatttcgtca tgttcggtat ctcctactgc
    57541 tggataaagc ataattgatt catagttttc tttttgttgc gcaatgatct gccctttttt
    57601 catcaattct agcaaagcca taaaagtagt gacaacttca cttttagaag gtgactcaaa
    57661 aaaagaatcg aaagtacagc catgcgcatt tctttttata cgctcttcga taaataccat
    57721 tcgttcttcg atcgttgtgt catcgggcgt gatcgttttt tccacttttt gagaaaattt
    57781 cttacgttct aagattttct gcatggcacg gatcaaatcg atttttttga cttgtcctcg
    57841 cttcaacggc ttttcagcat ccgctaaccc atcgatgttc ataggttctt ttgtgtaata
    57901 aagacttcgt tcctctgctt tttctgtcag tctttcagct gcatatttat atttacggta
    57961 ttctaaaagc tgagtgacca attcttctcg aggatcttct tcccataatt cttcatcgtc
    58021 tgtgacgaat tcttggacag gaagcaatgt cttgcttttg attgccatca atgtagcagc
    58081 catcactaag tattctcctg caacagctag ctcgagtgtt ttcattgtat ggatataatt
    58141 catatattgc tccgtgatcg tagcgatcgg tatatcatat atatcgattt ccatttgctg
    58201 aatcagatga agcagcagat cgagaggacc ctcgaataca tctaatttaa tattgatctc
    58261 cgtcaactca ttcactcttt cttctttttc tttgctagcc attttccaat gtaaggctct
    58321 gtgatttcag ttgcacggat ggagacatcc gggtactttt cctgtaattc atctaacatt
    58381 tgaaagccca tattctcacc gcgataagac ggattcaaag aaatgtcatg gatgatcagc
    58441 tgatcgttcg ttgcccagta aataccaata atcccttgaa tgttggttga accttctggc
    58501 gtaaagaaaa aaagttcata atcgtcttca gattcgtacg tatcaatctc cttcaacaaa
    58561 gaagttttac ctgtcagttt cttatggaaa ctcaatagtc ccatagcaat tttacggttt
    58621 tctttccggt aatgtgttaa catcttctca ccttcctatg actaagccct tggaaaatgc
    58681 tgcttataaa catccgtcat tcttttcttc gtgatatgtg tataaatctg agtcgtagag
    58741 atatccgcgt gacctaacaa ttcctgtact gtccgcaaat cagctccatt ttctagcaga
    58801 tgtgtggcaa agctatgccg cagcgtatgt ggtgttactt ctttgtaaat cccagcctct
    58861 cgtactaact gcttcagatt tttccagatt ccttgccgag aaagaccttt cccatgatta
    58921 ttgacaaata catgcatttc agatgcgtcc tttacaagta atggacgtgc ttcgtctaag
    58981 tagcgttcca gccattggat cgcataatca cctaaaggaa tgatccgctc tttatctcct
    59041 tttccaactg tctgtaccag tccaagagaa agatgaagat ctcccaattt caatccaatc
    59101 aattcactga cgcgcatccc agtagcatac atgacttcca agattgcacg atctcttatc
    59161 cctaacgttt ttgtcgtatc aggtgcttca atcagctttt ctacttctgt cagagtcaat
    59221 gtacttggta atttctgtgc tttcttcggc gtatcgatat gttgcatcgg atcatgatca
    59281 gtgatacgct cttgccgtaa aaactgatgg aatcttctga gacttgagat catccgagta
    59341 acagttgctg tcgctttttt ttcttcatgc aacttctcca gaaaacggat gactaaaaag
    59401 cgatcgacat cctgccatga agcaattttc tgctcctgta gaaaatgcaa gtactgttcc
    59461 aaatcacgtt catagctttg tcgtgtattg gcggacaatc cccgttcaat attcaagtag
    59521 tggagataat cgttgatttg ctctttcata ataatccccc tcatgcctct ctatcatatc
    59581 agataccgct tcattctgat agtctttttc cataatctga gcaaagaaaa agccgtctag
    59641 acactcagac ggactggttt cttttttctt tttcatagca ttcctgacag attccatgga
    59701 acgttagccg atgatctttt actaaaaaat gataacgttc ttctactact tgctccactt
    59761 caagtaaaag atcctcttct acttcctcga tcgtgccgca gttcaagcat agtaaatgat
    59821 gatggaaatg tttggcgcct tcttttctca aatcataacg ggctaatcca tcattaaaac
    59881 ttactttatc gacaattttc aattctgtca agatttcaag ggttcgataa acagtagcaa
    59941 gtccaatttc cggactcttt tttttcacta aaaagaagat ttcttctgca gataaatgct
    60001 ctttctcatt ttccaaaagc acaagcagag tagcttctct ttgcggtgtc agcttaaacc
    60061 ccgcttcatg tagctgctgt tttgtttttt tcatcgccga aatagcattc atgaccattt
    60121 actcaacccc aacaatttat aataattaca aataaaaaaa gatataacac tatgttaatt
    60181 aaaattatta taagctagtt aagaaaaaca tgcaagggat tctcaattag attttttgac
    60241 tagttttgtc acaccgtttt cttgtgtaat caatccttgt ttcaaaagat tacctaatgc
    60301 gcgcttaaat gctcctttgc tgataccaaa agctttcatg atttcttctg gatccgattt
    60361 atctgtaaag ttgatttgct gatctgcaga acgttctaaa atggttaaaa tcatttgtgc
    60421 atcatctgat atagcttcat atgctcttgg cttcaatgaa agattcagta caccgtctgg
    60481 tcggacacca atcactcgac cttttatctg ctcgcctaga cgaggttcat tatatcgttc
    60541 agaaggatgg ataaacccaa gatagaaatc ttccgttaaa acgtacgtac ctgttaattt
    60601 caagcggtat gctgttccta tcacatcttt gtttttcatt tcttctgttc catatttgct
    60661 taaagatttg aatatttttt catctgctaa actgccccaa atacggtctt ttgcatcaac
    60721 tctaagggaa atcatcaagc gatccccttt tttaggccat agctctgtca ttgtcggcaa
    60781 ttcatcaaga gatacgacaa agtctttatc tggaagaccg atatcgacaa acgcacctaa
    60841 atcttttcgt gtagcagtaa cgattccaaa agcgtaatga ccgatacggc ttttaggaat
    60901 ttgtgtagtg atccgatttt catgtttttg attttggtaa ccgaatcctt caactgcttc
    60961 accgattttg tgttcacctt ctgatttgct taagccaaag gtttgtccgt ttttttggac
    61021 aaagtagttt ttttcatttt catcaataat aatacctgta aatatagttg ctaataaatc
    61081 gttcattttt ttctccctct atagtgaaag gttttcttaa tacatttctt tgctatcata
    61141 acataatgtt atctacttga atagctgagc cttggtttgg aaaggtgaaa aaaggagtat
    61201 gacaacagtt gtgtcatact cccctttttc gaataaacgg tgttaaacgg caggctcaca
    61261 gcctctttca tttgcctaaa attaattgct cccatttcct ccgaaccatc cagttttaca
    61321 gttgatggtt acgatgtaaa atggcaaagc actttctcca atgcctttca tcaatgcaga
    61381 ttttgttgaa gtggcatata gattataata gccttcccca ttttcgattc tggctttttc
    61441 taatctgtaa cctccttcaa cgatatatcc acgttggata catgtagcaa tcactttgct
    61501 ttggacacct ggtgcccacg tccatgctgg attagatgca tcggcaatat cacttgctct
    61561 ggcagatttg attggctgat tcgctgagtt tgaagaggaa ggggtcgagg atgccgcttc
    61621 ttgctgtgct gcttgtgcga ccgcagcttg ttgagcggct tgagctgcag ctgctgcttg
    61681 agcggcttgt tttgcttgtt cttcagctgc ttttttcgct tcttctgctt ttttcttttc
    61741 ctcttcttct tttttctctt tatcagtgag catcttatct acttgtttca attgttcatt
    61801 caactgagca gatagatctg tatttttcac tttttctact gcttcttttg ccgtcttgta
    61861 ttggtcgcgt gttgctgaat ccactacttt tccgtcttta aagactatag ctgttttttc
    61921 tttagctgtt tgcaattcag catattgatt tttagcttct gtttgtgctt gttgaatcaa
    61981 ttttccaaaa tctgtgttat ccgtttcgat tgcttggatc tctttatctg ctttcaactt
    62041 gatgtcatct gctagatgat catcgacgat ggcaggtgct atgaaccact cattcacttt
    62101 ttggatatct cggatcttag attggatatc ttggtaagtt gtttctaact ctgaatatcc
    62161 tttttcattc ttaagactgg ataaatcatt ttttagtttt gataaatctt gatgaatcat
    62221 atctgcacga ataaattgat ggtgatcatc tgtataaaag gcagcaagtt tctcatgaag
    62281 ttcttccatt tgttgctgtc tttttgcttc tgctgctact tcggcttcta ctttttgatg
    62341 atggtcataa taagcccagc ttcctccacc gagtagaagt actgctgcta aaacgagata
    62401 aggtactttt tttgattttt tcttttgcgc tttatctgga tctgtttttt ctaagtttga
    62461 ttcttgatgt gttttttcag tatctggcac gattgttatt gatttcgctt ctgcttcaaa
    62521 cagcttaggc tggttctctt ctttttctat ttttgcttca agatcagtac cctctttgct
    62581 tacagattga ttttcagcat cggattcact atttatttca tcgggctctg ttgacttttt
    62641 gtctgtgttt tcgagtattt cttttttctc tgcttccggc agtttattcg ttttttcctt
    62701 ttctaattgt ttttcagtaa atacttcagt tttttctgtg atatccgttt ttacgtcttt
    62761 tatttttact gtttctttac ctgtggcgtt ttctctatca gagtcttttt cagtttcttg
    62821 ttccttttct ggctctactt tgttttcctg tgcaattttt tcactgatca ttttgagcag
    62881 ctctttcgcg tgctcttctt ttgtatcttc acgatgtgct ttgatataag cggatagtat
    62941 cgaattttct tcctcattat cgacgatttc tttcagttca gctactcttc ttttttgttt
    63001 tgattcaagc gtttcttctt gattctttcc tgattcttcc gaagtctcat gaacagttgc
    63061 tttcttctgt tcatttttct ctatattagt tacttgatcg tgagcaggtg gttcttcgtc
    63121 ttctggttct gctttttcga ataattccat tacagattct agaggtaaat ctttcaattc
    63181 cgaccattcg attggatcgt ttaattctgt atcaggaaag actgcatctt cagttgattt
    63241 atcctgcata gctgcatctg tatttgtttc ttcaattgat tcttttattt gctgatcttc
    63301 tgcagttatt tgatgaccgc agtctggaca gatagtattc tgctccattt ttttcgatcc
    63361 gcaatttgga cattttttca tcacttagcg atcggctcct ttactaggtt tacgctacca
    63421 tttaatctat catattctat acgtcacgcc aatagcttat ttttaggatt tacttaaaaa
    63481 taatgaatga atttccttcc tatagaaaaa aaagcttgag actgcgtagt ctcaagct
//
LOCUS       DACGMI010000007        61533 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.007, whole genome shotgun sequence.
ACCESSION   DACGMI010000007 DACGMI010000000
VERSION     DACGMI010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.007"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(59..187)
                     /locus_tag="IXT46_000548"
     CDS             complement(59..187)
                     /locus_tag="IXT46_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAQ4946490.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="IXT46_000549"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="IXT46_000549"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAQ4946491.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="IXT46_000550"
     CDS             complement(1674..2729)
                     /locus_tag="IXT46_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAQ4946492.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="IXT46_000551"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="IXT46_000551"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAQ4946493.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="IXT46_000552"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="IXT46_000552"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAQ4946494.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="IXT46_000553"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="IXT46_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAQ4946495.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="IXT46_000554"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="IXT46_000554"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAQ4946496.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="IXT46_000555"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="IXT46_000555"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAQ4946497.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="IXT46_000556"
     CDS             10491..12050
                     /locus_tag="IXT46_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAQ4946498.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="IXT46_000557"
     CDS             complement(12161..14092)
                     /locus_tag="IXT46_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAQ4946499.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="IXT46_000558"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="IXT46_000558"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAQ4946500.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="IXT46_000559"
     CDS             complement(15021..15773)
                     /locus_tag="IXT46_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4946501.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="IXT46_000560"
     CDS             complement(15932..16141)
                     /locus_tag="IXT46_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946502.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="IXT46_000561"
     CDS             complement(16152..17480)
                     /locus_tag="IXT46_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946503.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            complement(17845..18432)
                     /locus_tag="IXT46_000562"
     CDS             complement(17845..18432)
                     /locus_tag="IXT46_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAQ4946504.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="IXT46_000563"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="IXT46_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAQ4946505.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="IXT46_000564"
     CDS             complement(20012..21301)
                     /locus_tag="IXT46_000564"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAQ4946506.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="IXT46_000565"
     CDS             complement(21455..22387)
                     /locus_tag="IXT46_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946507.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="IXT46_000566"
     CDS             complement(22544..23203)
                     /locus_tag="IXT46_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAQ4946508.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="IXT46_000567"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="IXT46_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAQ4946509.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGASGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="IXT46_000568"
     CDS             complement(24244..24534)
                     /locus_tag="IXT46_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946510.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="IXT46_000569"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="IXT46_000569"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAQ4946511.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="IXT46_000570"
     CDS             complement(26821..28176)
                     /locus_tag="IXT46_000570"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAQ4946512.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="IXT46_000571"
     CDS             complement(28200..29369)
                     /locus_tag="IXT46_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946513.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="IXT46_000572"
     CDS             complement(29366..30253)
                     /locus_tag="IXT46_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAQ4946514.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="IXT46_000573"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="IXT46_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAQ4946515.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="IXT46_000574"
     CDS             34320..34841
                     /locus_tag="IXT46_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAQ4946516.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="IXT46_000575"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="IXT46_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="IXT46_000576"
     CDS             complement(36284..36940)
                     /locus_tag="IXT46_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946517.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="IXT46_000577"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="IXT46_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAQ4946518.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGSISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /locus_tag="IXT46_000578"
     CDS             complement(38477..39475)
                     /locus_tag="IXT46_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAQ4946519.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="IXT46_000579"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="IXT46_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAQ4946520.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="IXT46_000580"
     CDS             complement(40491..41222)
                     /locus_tag="IXT46_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAQ4946521.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="IXT46_000581"
     CDS             complement(41226..42491)
                     /locus_tag="IXT46_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAQ4946522.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="IXT46_000582"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="IXT46_000582"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAQ4946523.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="IXT46_000583"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="IXT46_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAQ4946524.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="IXT46_000584"
     CDS             47833..49335
                     /locus_tag="IXT46_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4946525.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="IXT46_000585"
     CDS             49337..50074
                     /locus_tag="IXT46_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4946526.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="IXT46_000586"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="IXT46_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAQ4946527.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="IXT46_000587"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="IXT46_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAQ4946528.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="IXT46_000588"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="IXT46_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAQ4946529.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="IXT46_000589"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="IXT46_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAQ4946530.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /locus_tag="IXT46_000590"
     CDS             complement(55574..56740)
                     /locus_tag="IXT46_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAQ4946531.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGNRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="IXT46_000591"
     CDS             complement(56756..56983)
                     /locus_tag="IXT46_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAQ4946532.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57370..57626)
                     /locus_tag="IXT46_000592"
                     /pseudo
     CDS             complement(57370..57626)
                     /locus_tag="IXT46_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            complement(57969..58992)
                     /locus_tag="IXT46_000593"
                     /pseudo
     CDS             complement(57969..58992)
                     /locus_tag="IXT46_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            complement(59630..60304)
                     /locus_tag="IXT46_000594"
                     /pseudo
     CDS             complement(59630..60304)
                     /locus_tag="IXT46_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313658.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            60827..61417
                     /locus_tag="IXT46_000595"
     CDS             60827..61417
                     /locus_tag="IXT46_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAQ4946533.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
BASE COUNT        17074 a        13212 c        10647 g        20600 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagcc cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgaac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attgggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atttccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacttgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg
    59041 aaaaatcgaa aaaaactcat tttgtgtcaa gttatctgta atatataaaa atatcattat
    59101 tatacctcat ctatgtgaat ttttactatt cttaccttag catattcttt ataggtatat
    59161 cagagctaat caaactaaaa aatacccgaa gtcttcttat gtaaaaacac cggttattac
    59221 ttaaatatga cttaggtaaa acaatgagtg atccaattat aaaattttat ggcgaataat
    59281 ttagtaagcg ctacatattg aatgatttag aaattttgaa aaagtagcta gttcctttta
    59341 taccagaaaa gtaaacctaa taaaaaacac aactaatttt tagctgtgtt ttttaagtta
    59401 caataattat ctatttaata gtcttaattc attaaaataa aaaactcaac tttacaagga
    59461 tatggtttaa aaaatttatt tatccaaccc aactagtttt cgctgcttac gatttgcttc
    59521 atctgctacg taattcatta ctgttttaaa ttctttcgct gaggcgtttt ctgataaatc
    59581 agcgatactt ttattatact tcttcacgat ttgttgtact tgttctttct cagtcatgta
    59641 attcctcctc caactctttt gaagtatatt gtattggtag tactaattga atattatctg
    59701 ctgcataatg cacttcagaa atgtcgtttt gataatcctt aatcattatg tgaaggacta
    59761 cttcaggatg tctatttttg actttttcaa tattctctct ggacttaaaa aacgcattga
    59821 taaacatttc ttttggcaca tgacgtcctt cagctagttc acgttttcga gtgaaatccc
    59881 aggcaacttt gggatcttgg taaacataga aaatcgtaac gcgaaagtta tttttaaggg
    59941 ctcgaataat atttttctct gcactaagga tagcaaaagt atcctctagt atgaaagaat
    60001 agccatgttc cagtacatat tttaatgatt gttcaactaa ccaagaagaa gctttctgaa
    60061 aaacacttga gttctttcca ttgtattctg gaaattgtgc tctaaaatag tccgcatcaa
    60121 tcacaacatg gttgtcataa ttttaagcta aacctagtgc aacctctgtt ttacctgctc
    60181 ctgggcttcc agccatgaat accgcatctt tttcatcatc agggattttt cccttgatga
    60241 ttgtttcaat aaatttatct ttattgaccc tagcgtaatc taaatacttg tctttaggtt
    60301 ccaagattgc accttctttc cttcttctat attcatacta attatacgat atttatataa
    60361 aaaatataac ggtcatttta accatattaa catttagtca cagtaatagc agatatgctc
    60421 gcaaaatgag atatgaatgt acgcagaatc cttgttttct acggcattcg cttttttttc
    60481 attggactag ttatatattt ctagggttgt tttcatgtct gagtgcccga tatgatttat
    60541 ttttcgtttc tataattact ttttgccttc cagtttcttt taagattgta ctcaagcaag
    60601 tgggaattgg ttcttttgtc atccatgtat gcaaaatgtt ataatgctgg taaacaaaaa
    60661 tgattacctg tcatttttat ttagttcgta tttaattaag ttgactgtct gtatactctg
    60721 tctaaaactt aagaattgtt gttttcgctg tcgctatcca aatttaatga atgtctgtat
    60781 gttaaaactg ttgtccttgt catagatagt aaaggagagc ttgaaaatga aaactgcgat
    60841 tacgtttcta ttagaggaat atgccgattg ggaaggtgct tatattacta gcacactaaa
    60901 ccaaaaagag ggatggcaaa acaaaactgc ttctatccaa tcagaggtca cttccattgg
    60961 aggattaaaa acaaaaatcg attacttaat cgaacaaata cctgaaaaag ttgacctttt
    61021 tattatgatc ggtggcaatt catgggacat aaaaaatcat catttatatc aaataatcga
    61081 taaattgtta aaaacagacg taccagtagc tgctatttgt ggggcagttg attatttagc
    61141 tcagagcgga ttattgcaag gttacaaaca caccggaaat gcgcaatttc cttggttaga
    61201 atcggaaaat tatcagaata aagaagattt tatagaacaa caagctgtga aagatcgtaa
    61261 tttgattact gcgaatggaa cagctcctat agaattcaca gacttgattc ttcaagcagt
    61321 ccattttgaa acagaagaaa taagagaaaa aaagattcgt ctatacaaac ttggattcta
    61381 tgattactat aaaaagtacg gagatccttt ctcctaatca ttctcttcaa ttaaatactc
    61441 cttatcaata gtatgacaag taattttact gatggttatt tgtcacactt tttctgacat
    61501 ttatcaaaga agatacactc tatttatatt cat
//
LOCUS       DACGMI010000008        57518 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.008, whole genome shotgun sequence.
ACCESSION   DACGMI010000008 DACGMI010000000
VERSION     DACGMI010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57518
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.008"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(61..2424)
                     /locus_tag="IXT46_000596"
     CDS             complement(61..2424)
                     /locus_tag="IXT46_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HAQ4946534.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2872..3093
                     /locus_tag="IXT46_000597"
     CDS             2872..3093
                     /locus_tag="IXT46_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4946535.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="IXT46_000598"
     CDS             complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="IXT46_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAQ4946536.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3575..5881)
                     /gene="infB"
                     /locus_tag="IXT46_000599"
     CDS             complement(3575..5881)
                     /gene="infB"
                     /locus_tag="IXT46_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAQ4946537.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5894..6205)
                     /locus_tag="IXT46_000600"
     CDS             complement(5894..6205)
                     /locus_tag="IXT46_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAQ4946538.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6202..6495)
                     /locus_tag="IXT46_000601"
     CDS             complement(6202..6495)
                     /locus_tag="IXT46_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAQ4946539.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="IXT46_000602"
     CDS             complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="IXT46_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAQ4946540.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="IXT46_000603"
     CDS             complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="IXT46_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAQ4946541.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8333..12685)
                     /locus_tag="IXT46_000604"
     CDS             complement(8333..12685)
                     /locus_tag="IXT46_000604"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAQ4946542.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12897..14606)
                     /locus_tag="IXT46_000605"
     CDS             complement(12897..14606)
                     /locus_tag="IXT46_000605"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAQ4946543.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="IXT46_000606"
     CDS             complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="IXT46_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAQ4946544.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16103..16903)
                     /locus_tag="IXT46_000607"
     CDS             complement(16103..16903)
                     /locus_tag="IXT46_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAQ4946545.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16900..17712)
                     /locus_tag="IXT46_000608"
     CDS             complement(16900..17712)
                     /locus_tag="IXT46_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAQ4946546.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17907..18464)
                     /gene="frr"
                     /locus_tag="IXT46_000609"
     CDS             complement(17907..18464)
                     /gene="frr"
                     /locus_tag="IXT46_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAQ4946547.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18467..19189)
                     /locus_tag="IXT46_000610"
     CDS             complement(18467..19189)
                     /locus_tag="IXT46_000610"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAQ4946548.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19325..20206)
                     /locus_tag="IXT46_000611"
     CDS             complement(19325..20206)
                     /locus_tag="IXT46_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAQ4946549.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="IXT46_000612"
     CDS             complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="IXT46_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAQ4946550.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21446..21925
                     /locus_tag="IXT46_000613"
     CDS             21446..21925
                     /locus_tag="IXT46_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAQ4946551.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22142..23233
                     /gene="phnW"
                     /locus_tag="IXT46_000614"
     CDS             22142..23233
                     /gene="phnW"
                     /locus_tag="IXT46_000614"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAQ4946552.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23226..24011
                     /locus_tag="IXT46_000615"
     CDS             23226..24011
                     /locus_tag="IXT46_000615"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAQ4946553.1"
                     /translation="MIKTVIYDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24357..26048)
                     /locus_tag="IXT46_000616"
     CDS             complement(24357..26048)
                     /locus_tag="IXT46_000616"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAQ4946554.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="IXT46_000617"
     CDS             complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="IXT46_000617"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAQ4946555.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27532..28551)
                     /gene="argF"
                     /locus_tag="IXT46_000618"
     CDS             complement(27532..28551)
                     /gene="argF"
                     /locus_tag="IXT46_000618"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAQ4946556.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="IXT46_000619"
     CDS             complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="IXT46_000619"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAQ4946557.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30332..31033
                     /locus_tag="IXT46_000620"
     CDS             30332..31033
                     /locus_tag="IXT46_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAQ4946558.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="IXT46_000621"
     CDS             complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="IXT46_000621"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAQ4946559.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="IXT46_000622"
     CDS             complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="IXT46_000622"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAQ4946560.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="IXT46_000623"
     CDS             complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="IXT46_000623"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAQ4946561.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33615..34439)
                     /gene="tsaB"
                     /locus_tag="IXT46_000624"
     CDS             complement(33615..34439)
                     /gene="tsaB"
                     /locus_tag="IXT46_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAQ4946562.1"
                     /translation="MYHCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDKIIVPMFDARRKNVYAGAY
                     RWKENRLEIVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFYEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            complement(34528..35508)
                     /locus_tag="IXT46_000625"
     CDS             complement(34528..35508)
                     /locus_tag="IXT46_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4946563.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35532..37016)
                     /gene="galT"
                     /locus_tag="IXT46_000626"
     CDS             complement(35532..37016)
                     /gene="galT"
                     /locus_tag="IXT46_000626"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAQ4946564.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37028..38017)
                     /gene="galE"
                     /locus_tag="IXT46_000627"
     CDS             complement(37028..38017)
                     /gene="galE"
                     /locus_tag="IXT46_000627"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAQ4946565.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            38266..38433
                     /locus_tag="IXT46_000628"
     CDS             38266..38433
                     /locus_tag="IXT46_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAQ4946566.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(38495..40306)
                     /locus_tag="IXT46_000629"
     CDS             complement(38495..40306)
                     /locus_tag="IXT46_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAQ4946567.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(40303..40668)
                     /locus_tag="IXT46_000630"
     CDS             complement(40303..40668)
                     /locus_tag="IXT46_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAQ4946568.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(40831..41226)
                     /locus_tag="IXT46_000631"
     CDS             complement(40831..41226)
                     /locus_tag="IXT46_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAQ4946569.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(41244..42206)
                     /locus_tag="IXT46_000632"
     CDS             complement(41244..42206)
                     /locus_tag="IXT46_000632"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAQ4946570.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(42206..42418)
                     /locus_tag="IXT46_000633"
     CDS             complement(42206..42418)
                     /locus_tag="IXT46_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAQ4946571.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(42439..43137)
                     /locus_tag="IXT46_000634"
     CDS             complement(42439..43137)
                     /locus_tag="IXT46_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAQ4946572.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(43157..43699)
                     /locus_tag="IXT46_000635"
     CDS             complement(43157..43699)
                     /locus_tag="IXT46_000635"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAQ4946573.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(43831..44835)
                     /locus_tag="IXT46_000636"
     CDS             complement(43831..44835)
                     /locus_tag="IXT46_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAQ4946574.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(44832..45821)
                     /locus_tag="IXT46_000637"
     CDS             complement(44832..45821)
                     /locus_tag="IXT46_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAQ4946575.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(45818..46624)
                     /locus_tag="IXT46_000638"
     CDS             complement(45818..46624)
                     /locus_tag="IXT46_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4946576.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            46790..47746
                     /locus_tag="IXT46_000639"
     CDS             46790..47746
                     /locus_tag="IXT46_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4946577.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(47823..48341)
                     /locus_tag="IXT46_000640"
     CDS             complement(47823..48341)
                     /locus_tag="IXT46_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4946578.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(48429..48578)
                     /gene="rpmG"
                     /locus_tag="IXT46_000641"
     CDS             complement(48429..48578)
                     /gene="rpmG"
                     /locus_tag="IXT46_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAQ4946579.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            48806..49252
                     /locus_tag="IXT46_000642"
     CDS             48806..49252
                     /locus_tag="IXT46_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAQ4946580.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(49447..51342)
                     /gene="asnB"
                     /locus_tag="IXT46_000643"
     CDS             complement(49447..51342)
                     /gene="asnB"
                     /locus_tag="IXT46_000643"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAQ4946581.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(51667..52641)
                     /locus_tag="IXT46_000644"
     CDS             complement(51667..52641)
                     /locus_tag="IXT46_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAQ4946582.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(52977..53064)
                     /locus_tag="IXT46_000645"
     tRNA            complement(52977..53064)
                     /locus_tag="IXT46_000645"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53030..53032),aa:Ser,seq:cga)
     gene            complement(53209..53775)
                     /locus_tag="IXT46_000646"
     CDS             complement(53209..53775)
                     /locus_tag="IXT46_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4946583.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            54030..55361
                     /locus_tag="IXT46_000647"
     CDS             54030..55361
                     /locus_tag="IXT46_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAQ4946584.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            55327..55677
                     /locus_tag="IXT46_000648"
     CDS             55327..55677
                     /locus_tag="IXT46_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946585.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(55769..56188)
                     /locus_tag="IXT46_000649"
     CDS             complement(55769..56188)
                     /locus_tag="IXT46_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAQ4946586.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(56189..56533)
                     /locus_tag="IXT46_000650"
     CDS             complement(56189..56533)
                     /locus_tag="IXT46_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAQ4946587.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            56883..57479
                     /locus_tag="IXT46_000651"
     CDS             56883..57479
                     /locus_tag="IXT46_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAQ4946588.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT        16183 a        12116 c        10052 g        19167 t
ORIGIN      
        1 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
       61 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      121 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      181 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      241 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      301 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      361 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      421 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      481 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      541 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      601 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      661 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      721 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      781 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      841 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
      901 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
      961 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1021 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1081 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1141 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1201 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1261 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1321 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1381 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1441 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1501 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1561 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1621 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1681 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1741 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1801 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1861 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     1921 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     1981 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2041 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2101 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2161 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2221 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2281 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2341 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2401 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2461 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2521 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2581 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2641 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2701 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2761 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2821 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     2881 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     2941 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3001 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3061 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3121 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3181 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3241 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3301 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3361 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3421 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3481 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3541 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3601 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3661 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3721 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3781 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3841 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     3901 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     3961 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4021 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4081 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4141 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4201 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4261 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4321 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4381 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4441 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4501 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4561 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4621 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4681 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4741 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4801 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4861 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     4921 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     4981 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5041 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5101 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5161 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5221 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5281 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5341 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5401 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5461 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5521 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5581 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5641 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5701 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5761 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5821 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     5881 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     5941 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6001 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6061 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6121 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6181 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6241 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6301 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6361 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6421 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6481 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6541 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6601 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6661 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6721 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6781 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6841 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     6901 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     6961 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7021 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7081 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7141 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7201 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7261 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7321 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7381 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7441 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7501 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7561 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7621 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7681 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7741 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7801 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7861 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     7921 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     7981 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8041 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8101 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8161 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8221 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8281 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8341 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8401 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8461 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8521 cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt
     8581 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8641 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8701 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8761 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8821 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     8881 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     8941 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9001 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9061 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9121 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9181 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9241 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9301 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9361 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9421 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9481 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9541 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9601 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9661 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9721 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9781 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9841 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
     9901 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
     9961 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10021 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10081 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10141 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10201 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10261 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10321 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10381 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10441 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10501 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10561 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10621 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10681 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10741 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10801 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10861 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    10921 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    10981 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11041 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11101 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11161 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11221 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11281 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11341 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11401 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11461 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11521 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11581 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11641 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11701 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11761 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11821 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    11881 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    11941 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12001 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12061 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12121 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12181 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12241 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12301 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12361 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12421 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12481 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12541 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12601 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12661 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12721 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12781 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12841 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    12901 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    12961 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13021 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13081 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13141 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13201 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13261 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13321 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13381 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13441 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13501 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13561 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13621 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13681 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13741 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13801 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13861 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    13921 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    13981 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14041 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14101 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14161 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14221 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14281 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14341 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14401 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14461 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14521 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14581 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14641 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14701 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14761 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14821 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    14881 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    14941 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15001 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15061 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15121 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15181 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15241 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15301 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15361 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15421 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15481 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15541 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15601 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15661 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15721 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15781 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15841 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    15901 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    15961 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16021 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16081 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16141 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16201 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16261 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16321 ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg
    16381 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16441 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16501 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16561 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16621 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16681 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16741 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16801 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16861 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    16921 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    16981 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17041 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17101 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17161 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17221 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17281 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17341 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17401 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17461 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17521 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17581 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17641 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17701 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17761 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17821 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    17881 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    17941 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18001 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18061 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18121 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18181 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18241 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18301 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18361 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18421 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18481 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18541 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18601 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18661 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18721 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18781 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18841 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    18901 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    18961 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19021 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19081 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19141 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19201 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19261 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19321 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19381 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19441 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19501 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19561 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19621 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19681 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19741 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19801 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19861 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    19921 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    19981 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20041 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20101 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20161 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20221 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20281 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20341 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20401 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20461 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20521 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20581 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20641 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20701 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20761 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20821 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    20881 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    20941 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21001 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21061 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21121 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21181 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21241 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21301 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21361 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21421 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21481 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21541 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21601 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21661 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21721 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21781 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21841 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    21901 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    21961 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22021 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22081 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22141 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22201 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22261 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22321 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22381 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22441 actgaactat accgtttatg aggtatcgga acatcaaatc ctccaagctc atgtgattac
    22501 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22561 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22621 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22681 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22741 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22801 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22861 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    22921 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    22981 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23041 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23101 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23161 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23221 cgttaatgat taaaactgta atttatgatt gggcaggaac aactgtggac tttggctgta
    23281 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23341 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23401 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23461 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23521 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23581 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23641 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23701 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23761 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23821 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    23881 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    23941 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24001 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24061 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24121 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24181 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24241 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24301 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24361 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24421 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24481 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24541 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24601 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24661 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24721 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24781 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24841 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    24901 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    24961 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25021 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25081 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25141 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25201 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25261 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25321 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25381 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25441 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25501 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25561 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25621 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25681 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25741 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25801 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25861 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    25921 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    25981 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26041 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26101 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26161 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26221 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26281 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26341 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26401 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26461 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26521 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26581 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26641 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26701 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26761 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26821 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    26881 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    26941 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27001 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27061 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27121 cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27181 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27241 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27301 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27361 atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc
    27421 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27481 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27541 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27601 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27661 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27721 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27781 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27841 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    27901 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    27961 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28021 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28081 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28141 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28201 ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac
    28261 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28321 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28381 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28441 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28501 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28561 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28621 agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28681 gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28741 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28801 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28861 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    28921 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    28981 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29041 cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa
    29101 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29161 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29221 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29281 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29341 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29401 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta
    29461 tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac
    29521 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29581 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29641 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29701 ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29761 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa
    29821 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    29881 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    29941 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30001 ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata
    30061 tttattcatt gaaaaaaatt ttttgaataa attaaaaaaa taaattatat tagcgttgtt
    30121 agcgtttact atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa
    30181 ttattcaata ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa
    30241 acttgtttct aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa
    30301 atatagtgaa caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt
    30361 ttcaaaactc agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat
    30421 caaggaacat actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga
    30481 tcccagacaa cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga
    30541 aagtgcaact tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg
    30601 aatgtttgga gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt
    30661 ctaccttcct gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta
    30721 tatgatacaa aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt
    30781 gacctctagc gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg
    30841 cgtaccaaca aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc
    30901 agtgaatagc ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc
    30961 cggactgtta gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc
    31021 tatgagagaa taacgcgaac aaaaataagc agtgaccctg atatttatca gggtcactgc
    31081 ttattttcct ccctaaaact tctgaaagat ccggcagttt tagatcactg ggcaagactc
    31141 aaagattttc tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgata
    31201 gattaactag aggaagcgtc ttgtcctcat ccgacctaga ttattcgata ttcctcgaca
    31261 ataaacgatt aatcagtgag ggcaatcaga ggaacggata atgatgaata agctgtaaaa
    31321 aatagggctt tgacaaaagc gtgtcacagc ccttatttcg attaaacggt gtgtacctgt
    31381 caactcttcg gtcacaagtc ataatgttca taaacatgag gagctgtttt ttgaaattgt
    31441 tccttgtgaa tcagagttaa acgacaggct tacgaactct tgattaaacg gcgttcaaaa
    31501 gcttgcatac gcggtaataa gaacagccag gtcaaaaaca tgagaagccg tttttcctgg
    31561 gctgttctta ttacttgatg cagggcagat ttttcacaac ctctttattc agataaaacc
    31621 aagcttggat cagcattcaa ctgatagcta gcaaaatttc ttttttgcat ttccacatgt
    31681 gctgctgctc caatcattgc agcattatct ccacaaagtc gaagaggggg aatcactagt
    31741 tctacctcag ggagtttagt tgccaaagca tcctgcaatc cttcacgcaa cccttgattg
    31801 gccgctacac ctccagctac aatcagttgc ttgactggat aattttgaca agctcgaagt
    31861 gttttagtaa tcaatacatc gatcacactt gcttgaaagc tagctgctaa atcatttttg
    31921 tctagatctt ctccacgctg ttgtgcatta tgcaccaaat tgataaatgc actttttaat
    31981 ccgctaaaac tgaaatcata attatcttca tggatcatcg ctcgtggaaa atggtaatta
    32041 tcttttccct gatgagctag ctgatcgatt tcttttccgc ttgggtaaga aagacctaat
    32101 actcttccaa ctttgtcata agcttctcct gctgcgtcat ctcttgtctc cccaatgatt
    32161 tcatatgatc catcttcttg catatagact aattctgtat gtcctccgct aacaagaagt
    32221 gccatcaatg gaaactggaa tggtttaacc agacgggctg catagatatg ccctgccata
    32281 tggtttacag gaataagcgg caattggtgt gcccaagcaa aagccttagc tgcagaaata
    32341 ccaatcagca acgagccgac aagtcctggt ccataagtga cagcgactgc cgataaatct
    32401 tctgccgaca caccagcttc taccagtgca tcttccaagc ataaggtgat ttgttctacg
    32461 tgatggcggc tagctacttc aggaactacg ccaccaaaac gtttatgact gtttatttga
    32521 gaagcaacga tgttagataa gatctctgtt ccatttctaa cgaccgctac actcgtttca
    32581 tcacaacttg attcaatcgc cagaatcaat tcttcattca tttcatcgtc tccgttttta
    32641 actttctgct cataatgatc gcatcttccg tcggattgcg ataatatgat ttccgtttac
    32701 ctaatatacg aaacttttct gattcataaa gttttcttgc tgcttcatta gatagacgta
    32761 cttctaaaaa aacatgcagc gaatctttta tttgttccgt aatcagtaat tgtaacaaat
    32821 gccgtgcatg cccttttcct tgttctgaaa ctgcaacagc aatatttgtg atctcgactt
    32881 catctattac tttcgagtat ccaataaagc cacagatctg gttatcttca actaaaagca
    32941 gataatcaga gtgaggctgt tggatgtctg ccaaaaactg cattttcgtc caaggtgaac
    33001 catgtggata agcattttcg ctaatcatcc atacgcattc tgccaagtac gcttcatcaa
    33061 aatctttttt tctgcaaatc aactaatctc actcattttc taaaagtttt atcatatcca
    33121 acgcatcttc ttttgtttca gtgtaatatc tttttttgat cgttgttgct tgaaaaccta
    33181 acttccgata aagtctttgt gcatcttgat tactcatacg cacttctaat gacatcgtct
    33241 cacagcgatt cattatagca aagttctcga tttcgtcaat aagcagcgaa ccgattcgtt
    33301 tacgctgata tgccggtcga acggcaatat tcgtgatatg gcaatctaaa ccgaacgctc
    33361 ttgaaccgat aaaaccaatc attcttccat tatcaaagat acctagatat agatgaggaa
    33421 gcggtgactt caattctgat ataaaggcac tttttgtcca tggcaattcg ccattataga
    33481 cttctcgttc gacatccagc agctctttga tatcttctgt agtcaattct cttagtacgt
    33541 aacgacgatc gatttgttcg attgtttttt ctgtataaat cattttatct tgaaaaaagc
    33601 ttctggcata cgctctaaat tttttcaaca taactttcgt ctccaggtgt gtgcgtctcc
    33661 aaccattttt cttctgcttc tacccgtttt aaatagcgag gaagaaaagc ttgtttctct
    33721 gcaactggtt cagctaaagc acctaattga gccacagtta caccacttgg aatatcccat
    33781 gctggaactg tattaatcat cgcactaggc aatatttcct ttatttcata gaagaatttg
    33841 tgacaatcac tcccgacgaa ataaatagct tcattcagct tttgtagttg tgtgaacaaa
    33901 tcagaagcag aaatatgtac atcttcaagt acaatttcta atctattttc tttccagcgg
    33961 tatgccccag cgtatacatt ttttcttcga gcatcaaaca tgggcacaat aattttatcc
    34021 acaccgatgc aattagccgc gatggttttc agactagata ctcctactag ctctttatct
    34081 aatgtataag caatcgtttt tgctgtcgtt acacctatac gaagccctgt ataagaaccg
    34141 ggaccatcag aaaccgcgat tcggtcaatg tcttttggac ttatttgaag atctgcaaac
    34201 aattggtcga ttgcaggcat cagtgttaca ctgtggttgc gtttgatatt tgtttgtatt
    34261 tgtccaagaa tttgttcgtc ttctaccaca ccgatcgcca aagtttggtt tgcagtatct
    34321 attcctaatg taatcatata tttgatcctt tctgctatga cattctcgcc ttccattgta
    34381 gcatactttt ttattctgag gatgaaaata ccaaaggcaa aactagtaca atgatacatg
    34441 attatctgct ggcgggcaaa ttttgcccct tcctgaaaca caaaaaagct gcggtatcac
    34501 ttcatttccc cacagctttt ccatctttta tttcgttgat tctcgaataa tcaactctgt
    34561 ttccacaata atctttcttg aaaccggtgc tttggaatta cttaattgaa gaatcgtctc
    34621 cactgctagc tctcccatcc attcggtata aacttttaca gtagaaagag agggcgttac
    34681 atatttcgct acactgacat cattgaaacc catcacagaa atatcttctg gtaccactaa
    34741 acctttttct tgaatcgctt tcagtgcgcc aatcgctaat gcatcattag ctgcaaaaag
    34801 cgcatcagga acatgcggat tcgtttttaa atactgcttc actgcttgat atcctgactc
    34861 gacagaaaaa tctgcttcga taattggacc ttcgtcgtag cctttttctg ccaaaacttg
    34921 ttgaaatgcc ataattctgg gatcttttag ccgctgatgg tttttcttcg tatattctgt
    34981 tccagcaagc atagcgatat gttgcgcttt atgggagaca aaatgttcaa tgactttttg
    35041 aacacttgac ttaaagtcga caactagaga gtcgattcct tgagaagtgc cgtcagaatc
    35101 taccaaaagc aaggcatttt gggatccttt catttctaat aactgagctt cgtcgaattt
    35161 tcctagtgcg atcgttccat ctgtcggaag atcactaatg gaatcccacg tttctttcaa
    35221 taaagtaacg tttgcttctt ctgccttttt ttcgattcct agacgaatag ataaataata
    35281 aagatcttca agctcttccg tatcgtcgta ccactggatc aggcgaagcg tttgcttagt
    35341 atttgctgca tttttacgat gtttcgtata atttaagcgt tctgctgctt caaaaatttt
    35401 ttgctttgtg gctaagccaa cggaaagatc aggatcatag ttgagaactc ttgaaacagt
    35461 agcaggagaa actcctgcca actgcgcaat gtctttaatt gttgccattt gtctctcctc
    35521 cttttttacg tttataaaat tgcagtaaat cgttcaaacg ctgcctgtcc tttttcatct
    35581 cgcttgaata ctccagcgtc ttccagtaca cgtgcaaaaa cctgacctac agatttttgt
    35641 acgacatcgg tgaccgtatc tttcgtcaaa tcaggatgtt ctttttttaa ttgttctgcc
    35701 cacggacgat gatattcagc catctggttt tcttctccta ataagaaatg ctctacttct
    35761 actagttctg gtttcaaacg aggtggtaaa acagcaagcc ccattacttc gatcaaccca
    35821 atgttctcct ttttgatatg ttggacatct ttatgtggat gaaaaatccc atcaggatgt
    35881 tcttctgaaa cattgttgtc tcgaaggaca aggtccaact caaagtaatt gtcccttctt
    35941 cgtgcaattg gcgtaatcgt atggtgtggt gtaccatctg ctgaaaaagc tctgatagat
    36001 actgtttcat ccgaatatgc tttccacttt tccaatactg agttagctgc ttcaatcaac
    36061 aattttttct ctgttgattg caaacggatc acagacatcg gccatttcac gactcctgcg
    36121 atgacttgcg gataatctgc tagtttgata agtttttcta tcggtgcttt tgccatagga
    36181 aattcatgac gtcctgcctg ataatgatca tgagaaagaa tcgatcctcc aacaatcggc
    36241 aagtcagcat tcgaaccaac aaagtaatga ggcaagactt cagtaatccg aagcagtcta
    36301 gcaaatgttt cctttgtgat tttcatcggg cggtgttgtt ctgataaaat gatcgaatgt
    36361 tcattgtaat aagcataagg agaatattgg aatccccagc tttcaccgtc tagattcatt
    36421 cgaataatcc ggtgattggt gcgggctgga tagttcaagc gacctctata tccttcgttt
    36481 tccatgcaaa gcatgcaggt aggatagtct acttttaccg cctcgcgttc tgctgcgatt
    36541 tgttttggat ctttttctgg cttagataaa ttgattgtga tttccagttc accatactcc
    36601 gactctgccg gaaatttgat gttttttgcg atggctcttg ttttgatgta gtcatttttc
    36661 ttacttaaat taaagaaata ctcagttgct tcctctgggc ttttcgaata gtgctgtgca
    36721 aagaatgcat tgacgactga aggtggcggt gtgagaaaat ccattaattg cgcttcaaaa
    36781 atctcttgtt ctgctggcaa ttctgaaaga acaccatttt ctcttgcctt agcgacaagc
    36841 tgatccaata agtctacaga ttcttcctta actggtctta cttcaatgct ttctagagca
    36901 tcttctccta ccatccctaa aagacgattc tgtaaatata agcggtccat ttccatccat
    36961 ccgccagctt cgatcgcaag tgtggcaaaa tcacaaatcg tttgactgat tgacatatct
    37021 cattccccta ttcttcataa ccatttggat ggctgacatg ccaatcccat gctgttttga
    37081 taattgcttt gatatctgtg tattcaggtt tccaacccag aacctctctc gctttttcac
    37141 ttgaagcgac taatcggcta ggatctccag ctcttcttgg tgctatttct gctggaattt
    37201 cttttcctgt cacttctcta gctgcttcta gcatttcctt gactgagtat cctttgctgc
    37261 tgcctaaatt gaagaagttg ctttcatttc cttctttcaa gtattccaaa gctaaaatat
    37321 gtgcagcaat caaatcttct acttgaacat aatctctgat acatgttcca tctggtgtat
    37381 cataatcgtc tccataaaca gccaatgctt ttctttgacc aagagctact tgtaaaatga
    37441 ttgggacaag atgcgtttct ggtgtatgat cttctccgat agatgcatct gcttttgctc
    37501 cggctacatt gaagtagcgc aaagcgacat agcgcatgcc atatgcttgg tcacaccact
    37561 tcatcatttt ttccatcatc aatttacttt caccatacgg atttttagga ttagctggtg
    37621 tatcttctgt gattggagac tcttttggtt ctccgtaagt tgctgcagta gaagagaaca
    37681 cgattttatt cacattgaac tcgtgcatga cttcaagtaa gatttgcata ccgtatacgt
    37741 tgttgttgaa atacatcaat ggtttttcga cagattctcc tactaaagag cttgcagcaa
    37801 aatggattac tccttcaatc ggttcctttt caaatacgga acgtagaaat tctttatccc
    37861 ggatgtctcc ttcataaaaa tgagcatctg gatgtactgc ttgtttgtga cctgtgagca
    37921 aattatctac cacagctact tgatacccct tttgaactag ctggtctaca gcgtgcgaac
    37981 cgatataacc ggctccgcct agtactaaaa ttgtcataaa aaacactcct ttgattagta
    38041 aaattgtgtt tgttgattat atataattta aaaaaacgaa gtttactttt atggtgaaaa
    38101 caaacaaagt aaaatttcgt aaattcatat ggtaaattta taataaaaca tttagtaaac
    38161 attttcaagg attttttgca aaggtttaca aacaaacgta aaactagcct ttttttctct
    38221 tttgttccat aatagatata acaaataata aatgaggtgg attcaatgaa aaaatttgta
    38281 tctggaatat tagtaggaag tctggcaaca gccgctgccg ttgctggttt ggtcgcttct
    38341 gtgaaaaaaa cagtgatcga tccaattgac gaaaaagaag caatgatcga agaaaaccgt
    38401 aaaaaagcaa tgcgcaaacg cgtttctcgt taataattat ttaaaaacac gcatgaagac
    38461 ttgtgaaaga acagataagt catcatgcgt atttttattt gtcagtcaat ataagttgtg
    38521 ctattttatc tgcctgtctc agattccatg gatctgtata aggtctagct actgctgcag
    38581 ttagccaatc cacaccttca acaggtattc catagcaata aaagtcagac tggatttccc
    38641 ctgaagcatc aatcacgcga ttcgtacctc gctcaacatc tatagcttct gaatgataac
    38701 ttcctgtatt atctgaaaat gaaaaagggc gaacaagttt gttttccttc aaatttttta
    38761 tgacaggatt acttgaacga gaaaagcttg tttgtggcaa tcgagcttca atcaaatagc
    38821 gactgctgat ttctttatct tgtagagaaa taacatagcg gttgtgcttt tgctgaatat
    38881 caaatggcgg ttcgaacaaa tgaaaaatac ccgcatctat cagtgctgct aattctttcg
    38941 tccgaatgac tggcggaccg atcgttaaaa agctatttag atgagtaaac catccccata
    39001 gtatttcttt gtattccttt gcagaaaaaa cgtgccattc aatagcctgc cggattggat
    39061 cacgccagtc ttttaatgca tcaaatgttg aagcaaatgc tcctgtgcaa ttgccttttt
    39121 ccgcttcttt tatctgccct tcaataaatg ctcggctagc ttctgcaaag gactcatcct
    39181 gataggtaag aggaatttct aaatacgacc aatcccatct ataagggatt agtgctggat
    39241 gctttccgag acactcctct gaagagaggg agagaaaatc atgctcaaaa tttttctttg
    39301 gaatcggcaa atgatattct tcgatgattt tcttgtaata aaacaactca acgtcttttt
    39361 tcagatagtc aaaaaatgtt tcgccagtca aaaatcccga ctgatgccat tgctccaggt
    39421 tttcttttgt tagtaaccgt ggccatgcca ttgatccgcc ttgcttttgg tttcttcctc
    39481 gagggtaata agggagcccc cttcttgatc cactgtatac aatcggttcc ttgcctgatg
    39541 gatgatagac aagttttcct ttttcgttct cgaagcgccc ttctcttgat actgtaaaca
    39601 atccgacata atcaaaaaaa cttaagccta gacctcttaa aaagacattt tctttaggcg
    39661 gtatcttcga aagatcgaca tctgcaggat tagaaggaag ctgatacagt aaatcatttt
    39721 tctttgcgta gtctacccac actctttctt cttctgtctc atcattttcc cagtgaccgc
    39781 ttgctaaaac aagctgatcg atagaatagc tttgctgatc tgtctgtaaa agataaccat
    39841 cttttctttt gctgactttt tttactaaag aataaacaaa ctgaatagaa gctggaaatt
    39901 cttcttgcaa ctttgagaaa aaccagcgtt gatagagtcc gtataaacat cgagtagatt
    39961 gctgatcttt ttccagacga ttgatttctt ctataattag ttgcttattt ttggttaccg
    40021 tctgttcgat ataatctgta gcaggtcctt tactccattg aaacaagttg ggtccctgtg
    40081 ttaccaatcc tccactggac aatgtttcat ctgtaaaaag cgtcacttgt tgagaaacag
    40141 aattcattaa taactccggt ggctgattca accgccaaac tcgacctcca ggaccattgg
    40201 gatcgaaaag aaaaagttca agagaatgtc tgtcctgatt attatggaga atcctttctg
    40261 ctatacttaa tcctctaggt ccggcaccaa tgatccctat tttcatttgc atgcctccat
    40321 ttcgataaat tttttcaata aaacagcatg gttctgatgt tcattttttg caccataaac
    40381 aaaagtaatg actggatgtt ctttcataag ttgactgagt ttaaaaatag cttgcttctt
    40441 ttcttcttcg aaaatcaatt cttgctggta tttctttgca aatgaagcaa atcgttctgg
    40501 tacatggtca aaagttttgc gtgcttcatt actaggtgca atttctttca accacagatc
    40561 taactgcgct ttttcttttg aaattcctcg tggccagaac ctatccacga gtattctata
    40621 gccatcctct ttttcagcat caaggtaaac acgttttaat ttgatcatag ttgtttcctt
    40681 ctttctgcct tttcgcttag cttatatatg tagataatag cacaaaataa aaaaaatgaa
    40741 cggcacaact atccattgcg ccgttcatgt gatcttggtc aaaatctaat gattgattcg
    40801 gtttttaaag ctgtcataca atcatctgtt ttatactttt ttacttttga tttttccaga
    40861 ccatccgtca tatccaccct taagtaaata aatctcttga taacctgctt tacgtaattt
    40921 atttgctgta cggatgctca agcttttctt ttgatcgtaa atatagacag gctggtcttt
    40981 tcgaatagat cctaatgaat ctttcaaaac agtgtaaggg atgtttcttg cacctaaaat
    41041 atgcccagca tcaaacacat ctttttcgcg aacatcgatt acttgtgctt ttctcattcc
    41101 ttctcgaaat tcttcttctg tcaaagtcgt tgctgaacgc ttggccatta ctcgtagata
    41161 gacttcccaa aagatgattg caagcacaat caatagcaaa atgatattaa ttacccataa
    41221 aaccatgtaa tgcctccgtt tttttaagca aatttcaagg ctaatgaggc agcaccaatg
    41281 acaccagctt cattaccaag ctctgctaat ttgatttttg ttgattctct tacttgcggg
    41341 aaagtaaatt ctttaaaata tttctctaca cggctacgta aaaattctcc tgctgccgat
    41401 actcctccac ctaacacaat acttgacgga ttcaatgtat tccccaagtt ggcgcaagct
    41461 aaacctaagt agaagcatac gcgatcaaca accatcaatg caaacggatc gtcttcttga
    41521 gccatttcaa agatatcttt acttgttact tcttcaccgt tgtctaacat tgctttcagt
    41581 tttgaatctc ctgcgtattc ttctgccaag taacgaccta gacgtaccac accagtagcg
    41641 ctagacacag tttctaaaca tccgcgttta ccgcaagtac attcgaaccc ttcaggatcc
    41701 acagtgatat ggccgatctc tccgcctgct ccgctcacgc cgtgaatcaa atttccgcca
    41761 gcaacgatac caccgccaac acctgttcct agagtaacga atacaacgtc tggatcgttt
    41821 tctccagcac ctttccatcg ttcacctaaa gcagcaacat tcgcatcatt atcgatagcg
    41881 aatttgattc ctgttcctgc ctcgatcagt tttttcacaa attgaacttc tgtccagttt
    41941 aagttatacg caccaataac cgttccagct tcgctgtcca cgcttcctgg ggtacccatg
    42001 ccgattccga taaagtcttc ggctttcata ttatataaat tcaaacgatg gttgattgat
    42061 tcaatgattt caggaacgat atgcttacca tcatccaaaa tattggtatc gatgctccat
    42121 ttttgttgaa tctctccttc tggtgttaaa attgcaaatt ttgctgttgt tccacctaaa
    42181 tcaatcccaa taatcttctt gtccattaca aatttccttt ctttcggctt tcttcaattc
    42241 ggtgctctct ttttaatatg cgccacgctg tcatgtatgt atcatgatca atcaaacggc
    42301 tatcatacag attacgcaat tcgatagtca ttaattcaat gtcatagatg cgtgcaccca
    42361 catagataaa gatgccaaat tttttgaaca gctgctgtac atcatataag ctctccatct
    42421 ttaagcactt ccttcatatt atacaagtaa accatatttt tttaaaccca gtaaaataca
    42481 tattacaaaa agaaatacaa aaactagtgt agaaagaatc ctttggtgta tcgaatagct
    42541 tgtctgttgt ttcggtagac ccaaaacatt ccctaacact aatccgccaa ttagcccacc
    42601 gacatgtccc caaacatcta cagaggtatc cagaagacca aaaacaaatg tcaacacaat
    42661 aaataaaaga aaatgtctga ctagctgctg gatcgctggg ttatgtttaa aatgaaaccc
    42721 taagataaac aacgcaccga acaaaccgaa tatcgaagta ctcgcaccac cagacagaac
    42781 attcgcttcg ttaaaagcaa agcttgctgt atttcccatt atcccgctga acatataaat
    42841 caagaaaaaa cgccaatggc catagattgc ctcgatttgc tgccccataa aatacagtat
    42901 cagtgagttc attacgaaat gcatcagtcc aaaatggatg aagattggtg tcactaaacg
    42961 ccaccattca ttgaagtgaa caagataagg accatacatt ccggcataat aagggatctc
    43021 aagtcgcgga aataattcca tcatgaggaa gaccgctgtc tgtatcccta aaaaagcata
    43081 ggtccataac ggtcgtctta accatgcacg caattttatt tgctgttgat aattcatgaa
    43141 aacctcccat ttcattttag tcaataaaca attgttggat cttctgatca aagctctccg
    43201 gttgccattg ttcattcaat tgttcacgaa aaacaaggct acatgttttt ttatgaaaat
    43261 tatttaaata ccggtcgtaa taaccaccgc caaaaccgat tcgataaccg gctctattgt
    43321 agataatacc tggtacaatg aggagatcga tcatctccgg caaatagagc ttctctgatt
    43381 gtggctcaag aacaccaaaa ctcgaacgta caagaacgga ctgttcatcc atttcataaa
    43441 acgccatctg acgtttcggc aaagttttag gtacaactat tttcttttgt tctttttctg
    43501 ctcgttggat aaccggctgt gtatccagtt caaattcatt cgataaagtc gtccctatca
    43561 cttttgctga cttccagtac tcgctggcga atagctgttt atagattcgc tgttcttttt
    43621 cctttttctt gccacttttg gccagatttt tcagcttttc gattcctttc cggcgtaatc
    43681 ttactttcaa ttggtccaaa aactcaccct tccttctctc ataaaatggt ataggaaaaa
    43741 aagaaaaata gcaatcgaac tttcaaataa atgcataaat agaataaaaa gaagacctag
    43801 aaatgattgg ccttcctttt ttaataaatt tcaactgttc agcgcgtgtt tttgtctgat
    43861 aaaaagtgca tacagaaaat atggcgcacc aaaaagggca atcaaaattc ctgtaggtac
    43921 ttccccactt ggtagaatca ctctagcaac catatctgca ctaagcagaa aaatggaacc
    43981 gaacaaaccg ctcagaacaa aggtccagtt attttcttta cgtacgacta gcttcgcagc
    44041 atgaggagct agtagtccta caaaagataa actacctgtc accgctacac taccgcttgc
    44101 caaagcaaca gctaacaaca aaaggatttt ttgactttta gccacgttaa ggcctaatcc
    44161 ttgcgcgcgt tcttgaccaa atgatagcaa tccaatcctc tgtgcataaa gtcctcctag
    44221 cggaattaag ataaccgccc atggaagcaa tgcccaaaca taaggccagc tcgcacccca
    44281 gattgatccc gctaaccatg cattcacaaa tccataattt tccttagata attggatcgt
    44341 gcatagcaat gttaatgcag aaaggccggc attaacggca ataccggaca ataagattcg
    44401 attcataccc aaaaagccat ttcgatcata ggccgcaaga tagacacagc aagcagctaa
    44461 aacaccacct agaaaggcta caactagcaa tagaaacggc agcgaatagt gcgaaaagaa
    44521 acctaaataa agcatcacta aaaatcctgc tccggcatta atgcccaata tactagaatc
    44581 tgccaattca tttcttgtta ctccttgcaa gatataacca gaaacgccaa gacaagctcc
    44641 tgctaataaa ctgatcagta atcgaggaac tcgaaattct ctaacaatca gcgccaaaga
    44701 agatgattct ttccctatga acgtggcaaa aagctgatcc aggtaaataa aaggcgtacc
    44761 aatcattaaa ctacctatag acaggatgac aagtacaaaa agcaagaaat agaacgtcca
    44821 atatattttt ttcaccgttg ttccctcctt acttgtatca gtaaaaacgg aacgccaatc
    44881 aatgcaatga ctaatccaaa aggtgtttca aaagggggat tgatcatcct cgctgtaaaa
    44941 tccgccaaca taaccaatcc accgccaact aaaaaagaga caggtagaac ataacgatag
    45001 tccgttccaa ccattccgcg aacaactggc ggaaccaaca gcccaataaa tgaaacaggt
    45061 ccgactaacg aaacggcaat ggctgctaac actgcaacta gacagaaaac aatcaaccgc
    45121 gttcgtttag gatgacttcc aagagctaat gcatgtgttt cactcaaatg aatcaaagat
    45181 attgcttttc ctaatgaaaa agaaaccaaa acagcaagta tatataaagg aaacaatact
    45241 gctaattgtt tccatgtgat attggcagct ccgcctacaa accaaaaagc aagatcctgc
    45301 tgcagattaa agaattgggt aagtgcttgg ctgatagcag taaaaaaaga actaatagct
    45361 acgccagcta aaatcagctg taaaggattc atgcccattt tcgaaaactg caaaaaacca
    45421 aatacgagca aagttacagc aaaagaacct gccaatgaca ttagaaacac agaaaaatca
    45481 gaagctttag gccaaaaagc aaaactaagg gccattgcca acgaagcacc cgcgttgatt
    45541 cctagtaagc ctgaatctgc taaaggattt cttgtcactc cttgcatcaa tgcaccgctc
    45601 aatgcaaaac aactccctac aagaaatgct cccgccacac gaggcaaacg aatatttcgt
    45661 atgatttggt gactttgttt tgatctatca aaatcaaaca acgcctgcca aaaatctgct
    45721 tttcccacag tcgctgcgcc atttgaaaga gcaacaaaaa aaataatcaa aagaacaaaa
    45781 cagaccaaaa gcaggagtct atttttcttc atagtcctca taattgatcc tcctgctctt
    45841 ttggcaacaa atcataggtt agaaaaactg gtttatttgt tcttggaagc gtgacaatcg
    45901 ttgcatcaat ctcaaatatt tttttcatac actcttttgt gatcacttct tcaggtgtac
    45961 cttctgtgat caacttaccg tttttcattg ctaataaata atctgaaaaa cgtgaagcat
    46021 gattaatgtc atgaatcgac atcaagatcg ttgtttgttt catttgattg atttcagtca
    46081 ataactgtag gatctctaat tggtgtgccg gatctaaaaa tgttgtcggt tcatccaaga
    46141 tcaagatatc tgtttcctga gcaagcgcca tagcgatcca gacacgctgg gtttgtccac
    46201 cagacagcgt tgcgatatcc cgcatacgaa atccagctag acctgtagca tccaacgccc
    46261 actcgattgc ttcatgatct tgcgtgtcca tgccactgaa cagtttttga taagggtatc
    46321 gtccgtaaga tactacttct tctactgtca tacctgtagg gtgttcacta gtttgtgcta
    46381 ataatgtaat tttttttgca agttcttttg aactgtatgt agagatatca gagttattga
    46441 caatgatctt tcctgatttc acaggtagta tacgggtaaa acttttcaat aaagtagatt
    46501 ttccacttcc atttggccca atcaaactag tgattttccc ttcaggaatc gtaacagaca
    46561 tgttttcaat gatttttttg ttttcgtagc cggctgcaat gtcagctgct cttaatctcg
    46621 tcatttcacc catcctttcg ctgaaaatca ttctcaatta tgacgctgtt tcaacatttc
    46681 gtcaagcgct actttcatat ctatagccaa atgaagcggt tgacagcgtt cgaaatatca
    46741 ggaataataa ccaatgagaa agattctcaa ttatgttagg aggaaagaaa tgaaattaaa
    46801 aacaaaagta ttcacattat ctagcatatt gctgctggct ggagtactga gcgcttgctc
    46861 cccctcttca gataaagaaa cagctacaac tgccaattcg acgacttcat ccaatagtac
    46921 tcatacagtc acagatacac ttggacataa agtagagatt ccaaacgcgc ccaaacggat
    46981 catcggcagt tacttagaag actatctgat tgcactaggg gaaaaaccta tcgcccagtg
    47041 gactgttggc agtggttcca ttcaagatta tctgcaagat gatttaaagg atgtcccaac
    47101 gatttcttat gaccttcctt atgagaaagt gttaagcttt gagcctgatt tgctgttgat
    47161 ttcttcttcc gctactgtcg aaggcgggaa atacgaacaa tatagcaaaa tcgcgccaac
    47221 ttatgttgta aaaaacggaa cagatgtcac atgggaagaa caactaaaag atgtcggcaa
    47281 agctttggca aaagaaaaag aggcagaaaa aatcatttcc gattatcaaa aatccatcaa
    47341 gaaaactcga gaagaactag cagataaaat cgagaacaag acagctgcag tgttgtgggt
    47401 gaccaacaac tcagccttta tggtcagcaa aaatcggtca agtggaagaa tcgtatacga
    47461 cgatctggaa tttggtgttc ctgatctagt ggaagaggtc tccaaaaaag ccacttctga
    47521 ctggtctgct gtttcctctg aaaagctagc tgaattagat gctgactaca tcatccttgt
    47581 gaacagtgac aaagatgctg ccatgttcaa tgaaccaagc tggaagaatc ttaaagcagt
    47641 gacagacaat catgtactgc aattcggacc tgaatctagt tggctatata acggacctat
    47701 tgccagtcag gaaatggtca atgatatcaa agaaaaacta aattgatttt aactaaaaaa
    47761 agaatcttca cgattagtcg tgagatgctt tttttcttat taacaaacta gacgcataga
    47821 ttttattctt cttttgaagc aaccctattt tttactcttt cccatttttg aaaacgatgg
    47881 gcatatagat tttcttgatc cgttatcccc tcatactcct ctataagggc gaagtctgaa
    47941 aaatcaatat tcccaatata cgtatcgcct tcaaacgtgc tatcgatcaa tgttcgccag
    48001 atccgaccag tgtaaggaag aagttcttga aaaatccgac taccacccga aacatagata
    48061 tcttctgaga tcgtttgact atacgacaaa agttcatcga tcgaatgcat tacttccgca
    48121 ttttctttcg tgcgaaaatt tggttgcgtt gtcaacacga tgatatggcg ataaggaagt
    48181 gaaagatccc ccattccttc ataggtcttt cttcccatca ctaaaattcg atccattgta
    48241 tgttcgcgaa agaaacgcat atcatttggc aatcgccatg gtaacaaacc atttttgccg
    48301 atcagaccat ttttatcttg tgcccacatg gaaataaaca tattatccgc tccttatgat
    48361 tttagatgtt ttgagataaa aaaagtctca attctttgac cagcaaggaa ttgagaactt
    48421 taaaaacatt attttgtttc acggtgcaaa gtaactttgc gttcgcgtgg gcaatatttt
    48481 tgtttttcca aacgatcagg attgttacgt ttgtttttgc ttgttagata gttacgttct
    48541 ttacaagaag tacactctaa agtgatgttt acgcgcatgt ttttccctcc catttttaca
    48601 agaatcctct aagatgactc tcagacttga ttatcttacc atgatttttt ctagattgct
    48661 agtgtttttc acgattttgt taagtaaaac tacttgacga taaatacaac ggttttactt
    48721 ctcaaacaaa atctttttct ttttgtataa atacccttac acttgtttat atagattatg
    48781 ttttttaata aagggggata ctaatatgcc atggaacatg aaggactttc ctgcatcaat
    48841 gaaaaactta gataaattga caagaaaaaa agcaatcgac atcgcaaatg cattattaga
    48901 tgaagggtac cctgataacc gtgcgatccc aattgccatt gatcaagcaa aaaaatggta
    48961 tgaagatgct agtgaatcag aaaaacgaac tttcgaaaaa gaaaaaaatc caagcaagac
    49021 ggatgaacac gatacgaatc ctcgtgctgg aaaactgctt gattcagatg tgatcgtaga
    49081 atatgaggaa gaacaatgga tcgtgaaatc taaaggggca aaaaaggcaa gcaaccattt
    49141 tgatacaaaa aaagaagcaa tcgaaaaagg aaagcaagta gcacaaaaca aagaatcaac
    49201 tttgttcatt tataaaaaag atgggacaaa agaaaaagaa atcgattatt gaacatatgt
    49261 aaaggggttg tgacgaaaat cgtgtcacaa cccccttatg ttcgaaacaa tggtgttcct
    49321 ctgccaactc cgaaccataa gtcataatat ctataaaacg ggaagagctg ttttttgaaa
    49381 ttgtttctta tcactcagtg ttaaacggta ggagaaaacc tcttttttat tgatatttga
    49441 ttttcatcaa acagtcacat agtcgattgc ttctgcttgc ggaatcgttt catctacaaa
    49501 gtagacttta taccatgtca agaaactgaa gattgtccag atttttcttt gctcttcttt
    49561 acgtccttcg tgatggtcat ctagcaactt catgattttt tcttgatcaa aaaattcttt
    49621 tgcaaaatct gcttcgaata atgctttgac ttgttcgtag ccgtgttctt ctttcaacca
    49681 agctttgatt ggcacaggga atcctaattt cacacgattc gaccattctt ccggaagatg
    49741 tttgttcgca gcttgtctga aaatatcttt tgtgttgttt tgattcaata aaaacttact
    49801 tggtatttgt tgagccaatt tcatgacttc gatatccaat aaaggtactc ggacttccaa
    49861 agaacttgcc atagaaagtt tatctgcctt taacaagata tcttttggca tccattgatg
    49921 aagatcgaca tattgcatct tattgacttc atctttgatt ccttctgttt tctcgtaatg
    49981 aacagtcatg atttcatcca cagatggtgc tgtttgatat tttggtgtta acacttctga
    50041 tgcttctgat tcttcgaaca ctcgagcatg accgataaaa tattcttttg caggagcaag
    50101 tgattcatat aaatggatcc gtccatggaa atttttcatt tttccgattt tacgtcctaa
    50161 attatagcgt gttccttttg gtaatttttt caatccttga gcaatcacac ggatgaattt
    50221 tgaattcgta tggaatccat acgtttggta tcccgcaaac agttcatccg ccccttctcc
    50281 agattggact acccgcacac tttgtgaagc aagatttgct aaaaagtaca aaggtacgca
    50341 agaaggattt gaatcaggtt catctaagtg atactggatc aaagggaatg ctttgaacga
    50401 catgtctccg tcgatcactg ctgctgtatt atctaagtcc aatagttcgg ttagttttct
    50461 ggcttcaatc gcttcattat aggttttatc atcaaacccg attgagaaag aatgatctgg
    50521 tttcaataca gaggttacat aactggaatc aaccccgctg gataagaaag aaccaacttc
    50581 tacatcactg accgtatgtg cttcaataga agcttgaacg gtttcgtcga ttttttcgat
    50641 ccattcttgt cgggaatgcg tttcttttgt ttcaaaatct gcatcccaat attgctgaat
    50701 gtctagtttt ccatctttat acgtataata atggccttca ggcaaacgat agacatcttt
    50761 gaagaatgtt tcgccgttta atggagaata ttggaaagtc atataaggtt tcaacgcttc
    50821 tttgttcaat tctttgttaa aatcaggatg aggcagaaaa cttttgattt ctgaaccaaa
    50881 cataaatgtt ccgttcattt ctgcataata atatggtttg atcccaaagt ggtctcttgc
    50941 accgaataac tcattctttt cattatccca aatagcaaaa gcaaacattc cgcggatctt
    51001 ttgcaataat tctgttcccc attcttcgta accatgcaaa aggacttctg tatctgcatg
    51061 tgtttgaaaa acgtggccag ctgcaatcaa ttcttctctc aaaggctggt aattatagat
    51121 ttcgccatta aaaataatga tctttgtccg atcttcattg taaataggct gagtaccgcc
    51181 ctctaagtca ataatactta atcttctgaa tcctaaagca acatgtttat cgatatattc
    51241 tcctgaacta ttaggtccac ggtgaacgat tcgatccatc attgtattaa taattgtttt
    51301 tttgttgtcc ttgtcgttaa caaaacctac aataccgcac atttaacttt cacatcctaa
    51361 tataaaatta ctgtttattt cattcatatg catcttatca tagaataaat agcggacgaa
    51421 tattttctct cttacaattt cgtcacgtga aaacaaaaga tgaaagtttc tgtttttaca
    51481 gaaaataaag tcccaatatc taatttacca tgttttcttt tttgaggcta ccttattctc
    51541 ttcgtgttaa aaaaatatta gtggatgcta tttccaaaaa aaacagcaaa aaaagacacg
    51601 acctaaagat cgtgtctaat tatgactgta tcagaaaata tgataccaaa cggatctatt
    51661 cattaattaa ttgacatagt ttatctgttg ctcttttatg actggataac tgaccaattc
    51721 atgacgatcc aagtcttctt tatttatatt tacagcagta atttgactgt cttcatacgt
    51781 acgataataa taaatccctt tatcaacgtt acagcaagaa gaataaatcg tatattcgta
    51841 ttttccttct ccagtatcgc atactccttt ttgttgctcg actgagccta gtatatgaaa
    51901 aaattgactg atactttcag attctgaatc acctgatgca gcattcattt tagtaaatgt
    51961 ggcttttaca aatcgagaaa cagaagagag atctccaggt aagcccaatc ctcccatccc
    52021 acgactataa acattcaagc tgatctggtt tgaaaaatga ttttctggtg ttccatttga
    52081 tagcgagcga taattgttca gattaaataa ttgataatca aatggcggat tatttgtcaa
    52141 cacaccgaca ggattatcat ataaatgaag tccatctttc atactttcaa ttactatcga
    52201 tttttcttta tcagctaata accagtgtaa aggtgacaag ggtagttttt cactaaaatc
    52261 gatattgact agattgatag tagccaataa ttctttagct tcgtctatgg ttgagcattg
    52321 ccctagtatc catggaataa actcaaatgg tgcaacgtta tcttttcctt cttgtaattc
    52381 tttataatca gcattgccag gaaaattcag tcctgccata ctcaaccctt tttcatttgt
    52441 agcctcataa tagagtggat agttggatac cccagctgct attcctatca ttgcataatg
    52501 tttatctaaa ttttttacct ttctaaaatc gaaacgataa tttcttggag taatagtgac
    52561 tacttcatta taagacatct cataatcaaa attccttcca aaataatggt ctttcgttgc
    52621 ataagtgatt gcggtacaca tcgttttccc tcctaaaaca aatcgttttt acacttttat
    52681 cttacatcta gtattttttt ttatcaaaaa aaaggccaaa gaagattgat ttactagcat
    52741 ttataaaaaa tagtactcag ggggaatcaa aaaatattgt aggttaaaag tacaacaata
    52801 aggggctgtg acaaaagtct tgtcacagcc ccttattccg aacaaacggt gttcaaaagc
    52861 ttgcatctgc ggtaataagc ccaaccaaac gaaaaaatag gaaaagctat ttttgtttgg
    52921 ccgttcttat tacttgatgc aggacagctt cttcacaacc tctaatcgtt gatataagga
    52981 aggtacagga tttgaacctg cgcgccggta ttagccggtt cgccggattt cgagtccggt
    53041 gcattaccac tctgccaacc ttccgtaagt actattttta aacttttttc acgaaatgtc
    53101 aagcctattt ctaatagata aataacagaa atcgcttttt ttagcaaaaa agtccattga
    53161 cagtttgcag ccaacggact taccgatcaa attcatactg atagaacact atctgattat
    53221 ttcaggatta tctaatgcta aaatcgagtc aattgtccgt ttgatcagtg caatgatttg
    53281 ttcttctgtt ggatgcatga tgtttgatga catcaatgac gctaagccag tcactgctac
    53341 ccatgtacca gtatgcagag catcgacata ttcatccgat aattgattgt atctttcatc
    53401 ttctttaact atttcacgga aataattgta tgaaaaatca tgcattttct ttccgtcccc
    53461 atgttcatca atgtacaatg ccatgtaaag actatgatgc ttttttgcaa agtagatata
    53521 gttcaaaccg agatcaatga ttttatcacc agtacgttca atagggaaaa catcttcttt
    53581 tagttgttca aagatagaat ccagcaacgt attttttaaa tcttccatgt ttttgaattc
    53641 cagataaatc ggctgtgtcg aaatccccat ctttttagca atatttctcg cagtaaatcc
    53701 tttaaaccct tcctttgcaa caacatcata agcagctttt agaatttgat ccttggtata
    53761 gacttttctt ctcattaaaa ctcccccact tctttactgc agtatatgtt gttttattgt
    53821 accctatttt tagcattttt tgcaaacatt ttactcaaaa cgttatattt taaatttttt
    53881 tcagtcttct ttaacttttt tttgcaaaat taaaaaaatt tggttaaatt caatgggttc
    53941 ccttacattt ttagttttga cctaaatgat agttgtccaa atctttcatt tcaagttata
    54001 gttaaagaaa atgaaaaaga aggtgtgtaa tggaaaacga aactgacgtt atttatattc
    54061 atcctcaaaa acgaatcgtt tcacagaaaa gaaagtattt ttatcttggt tttacaggtg
    54121 ttttttttct ttttattggc ttgctttcta atactcctac tgataattgg agtggattgc
    54181 taactattct tacctcgcca agcaatcttt tgacagatta ttttgcttta ggtgttttcg
    54241 gaagcgcatt cataaatgta gggattttga ccttactttc tgtgctttta gcttatcggc
    54301 acaaggtgat tttaaacggt cccttatttg cttcgattct aacagttacc ggtttctctt
    54361 tttttggcaa aaacctttat aattctatct caatcatttt aggtgtgtat ctatacgctg
    54421 tatttgtcaa taaacctttt tctcagtaca tcatgatcgg actgtttggt agcgtattat
    54481 caccggtcgt tagttatatc acttttggta tgcgttttcc tttactgata ggtattttat
    54541 tggggaattt agctggcata gcaattggta tacttcttcc gcccttagct gctcaaactt
    54601 tagttttcca tcgtggattc acactttata atattggatt cacctctggg ttgattgcga
    54661 tgacttttac tgctgttttg aggttattca gctattcaat cgtcgaaaat acattggttt
    54721 tcaatgaata tcactttcct ctcatttgga ttatttttgg ctttttttcg ctgacagtcg
    54781 gaattggttt ctattataat tcctttcggc tttcggggat tcgagaaatt ttcgattcat
    54841 ctggaaaatt gacaactgat ttcattgcta attctggtat tggtgctact ttgatcaaca
    54901 tgggcttagt tggtctgatg ctgtcttctt atgttttgct ggttggcggt cagttaaatg
    54961 gacctgtcat cggtgctatt ttatctgcgg tgggtttcag tgcttttggt tgtcatttaa
    55021 aaaacagttt tccgatacta gtcggaatat ttattgcttc tttgtttgga acttttcatg
    55081 agatcaccag tactggcatg cttgttgcag ctgtgtttgg gacaggtctt gcgcccataa
    55141 gcggttttta cggcagtttt tacggtgtaa tagctggtgt gctacatatt gctcttgtcc
    55201 ataacgtcag cactttgcac ggaggactaa atctatataa cagtggtttt tcaactggtt
    55261 tcgttgcagg tatccttgta ccgatactag ataactttac cgctgtcaga aaggaaaaaa
    55321 agacacttgg aaaaagaatt atcaaaaaga atcatcgatg agcttcttac ttatttatat
    55381 tcccatgaaa taactgaaat acgtattgga gtagaatttg ctgaggaagg gcttttcata
    55441 gagatacagg gtacggcaga aactcagcca gaagatttag atgtacttgc tgatttgctg
    55501 aacaatcctc gggaccctag tatggaaatc tactatcaag aactattagg taatccccga
    55561 catgatcggg aagattatca tctgttaggt agtttgattg atgacgtgga aatcatgtat
    55621 gcccagccga ttatcaatat taagatcttt cgacgtgctt ctcattccta ttattaaccc
    55681 tattttctat ttataaaaga ctgaatcaaa aaagcagctc ctgaaagttc gattaaaatc
    55741 tactttcagg agctgttcaa gcttgacatt attgattttc caatccttca tacacttcat
    55801 ctgttacagg ttctaaaaac tctgaattac cagcagtgat cgccaaatgt tcaaaccaac
    55861 tgtcttttgt cgcaccatgc caatgtttaa tccctttgtg cgttacgacg acatctccag
    55921 ccattaatcg tcttgctggc tttccttctt cctgatacca gccttctcct ccggtcacaa
    55981 gtaagatttg atagccgtct gtatggacat gccagtgatt gcgacaacct ggttcaaaag
    56041 ttacattacc tacaccaaca gaaacttcgg gatcattcac taacatattc agatagcttt
    56101 gcccggtaaa tacttgagcg taagcttcgt ttttttcacc tgctggaaaa atcacgccat
    56161 tgtgtatttc ttcgtgtttt gtcatcattt acgcctcttt cttatcttcg ctattttctt
    56221 ctaaatagat ttcttttgct aaactaaaag ctgaccaagc ttttggccat tctacataaa
    56281 aagctaaatg ggtaatgatt tctgctattt cttcactagt aatgccattt tgcttgccaa
    56341 tcttcagatg agctggcaat tgttcaaaat ttcctcctga aattaatgca gatatggtga
    56401 tgatactacg ctgatgagca gataattctt ctctggacca tacttgtcca aataaaacat
    56461 catcatttaa ttctgcaaat tttggtgcaa aatctcctaa ttgatctcgt cctgcggttt
    56521 gtttttctgc catttctctt attctccctt cacgactgtt aggtgattca actatggttc
    56581 taaggcaact ttattttcta ttgtttcttc gcatttcatt ttaaatgtag tctttcagcc
    56641 tgtccaatgc ttagtttatt cagtcgatat gctttttaag catagttgct aacgcttttt
    56701 ttattttaaa aaaaacaagt tattaaataa gtctttagtt ggatgttttt ttgagatcaa
    56761 tcttttatac ttatgatgaa cttacaaaat tgtttgtttt ctgtcatatc aaaaaatggc
    56821 gcagttagtt gcttttctag taaagtatag ttaacaaaga acctctaagg agttgatgaa
    56881 taatgaatat tgctgcctct cgaaaactga taaatttcat atccattatc ggattaggcc
    56941 tatcaatcgc gctgacgatt tattttatta atttaggtgt tttcaaagat ttgaatgcgt
    57001 taagaggatt agtaggtgat tccatcattt taggaccgat tatttttgtc ttcatccaaa
    57061 tcctgcaagt agttattcca atcattcctg gagggatcag tactgcagct ggtgtcctga
    57121 tatttggccc ttatgctgga tttatctata actatattgg aatctgcatt ggttcgatta
    57181 tcatttttct gctagggcgt cgttatggaa agccattcat actttccatg attagcgata
    57241 agacatataa caaatatatt ggctggctgg ataatcaaaa ccgttttgag aagctgtttg
    57301 ctctagctat ttttcttcca gttgctcctg acgatgcgtt atgtttgatg gctggattga
    57361 caaacatgtc agtgaaacga tatacactaa tcattttgat tgctaaacca ctgtcgattt
    57421 tcttatatag tatggccttg atttatggag gtcaatatct aagtggtctt cttggataat
    57481 atttattttg taaaattagt cattgattga caatgtta
//
LOCUS       DACGMI010000009        55728 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.009, whole genome shotgun sequence.
ACCESSION   DACGMI010000009 DACGMI010000000
VERSION     DACGMI010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.009"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            187..462
                     /locus_tag="IXT46_000652"
     CDS             187..462
                     /locus_tag="IXT46_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HAQ4946589.1"
                     /translation="MKNLVISKFAMLPRMDFFDNVSKFMSNMTSKLQGISLSVIIFCI
                     VVTGLMFLFGEGPSRTAKKWLTYIVIGAIIIFGASTIGQTIKSVGGF"
     gene            571..2397
                     /locus_tag="IXT46_000653"
     CDS             571..2397
                     /locus_tag="IXT46_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946590.1"
                     /translation="MNQRFEYNFEDVEPKLLKKGKGLKKKNKYTLKQAEALVGWIQHN
                     WSDKTTITLICSDTEEGTKYAFDGIEITPFSIGGQEKLLFPDIEGQILQAPDSMISDP
                     NKLILDINDQYKHEPDVAEPTKESKSKLNLKLPSVVLPFAKKKNKLMNELIEPEETDI
                     YEEELEEQEEIEELVVSSEETEEVEEIETVSENEEETEEIFDFEDEEEVENVQKGDLS
                     TSSQNGLEAVNDPQVPPYISSQTPNYSPQYQAPNVLQPLRKHETVQLVTLKEYCDLGE
                     EIETSISQMVEKLKPESLFKFIGIPSTGLTNTRIDEYRSNHAMLRLAEVKFENLREHY
                     SRQIISFKAEALDRLRTAVDIAWKKPYDLDVKKNKAEELSKMEAEAEAKLNEFVKRQE
                     NNVNDKIKKFEIEQEIDLKNFIARQEADKAVFIATEKDRTQNLIDSKAESINADLLET
                     KDKFIDEEMYKMKIEMNKNLFDGKQKIKSELATELAKANDNVWENALKFIQEIQDEIE
                     AKTPIWAAEIKEFNSLEEQEHERMKQTKELQLKEESIEIKRLEAEMNLKRMEELDHEN
                     KMLKIKLETALSKNELLAMEQDTKQVVNGSNRVGALNLFSKR"
     gene            2410..3126
                     /locus_tag="IXT46_000654"
     CDS             2410..3126
                     /locus_tag="IXT46_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946591.1"
                     /translation="MSVFNNKVMLGNCYVNHIGFYDGGTYRVLFLRLSVFSYSKDGKG
                     HYENINAQISCPLDRNGETTTTSSHPKALMNKFIFEKLDRNLVEGMKISIHGNIRGTE
                     QVLLNSGWKNFGQLSPLEKEEYQKIPKNELVTRNQTYIYIEEVSMPEKEEFRKSQSKV
                     TKEDVEVAEPNQADEILSDDTDPVNDEGEVIEVFEAEIIEEEEEIKSFDKRMYREKPK
                     GYVNFEDMYYDEYSNEPPIN"
     gene            3139..5997
                     /locus_tag="IXT46_000655"
     CDS             3139..5997
                     /locus_tag="IXT46_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAQ4946592.1"
                     /translation="MKLVQNNEVKEIKNGFVKNSNKILGKLKKVGSFKKNKYHTGKIE
                     GEDLPKSLQDKLNVPLVFIGVFLGSIVFLAITYLLNFLKALLVAIGQSESGLLGVEFD
                     PKFSLAYLKPLGDTKQYFMCAVVAVIGVAYLIYGKLNHESEKNLVYGQKGDSRLSTIK
                     EIKRDYHEIPEKTEVYDGIGGVPISHYQDKYYIDRDTVNTVVLGASRSGKGETFVVPL
                     LDNLSRAKIQSNMVVNDPKGELFSASKETLEKRGYRVLVLNIDDPLESMSFNPLQLVI
                     DSWANKDYHEASKRANTLTSMLFASGMSTDNEFFYKSAKSAVNAIILTIVEHCFNNDC
                     IEKITMYNVAQMLNELGSLFYTDPKTGKEKNALDEYFNTLPQGNQAKIQYGSTSFAGD
                     KAKGSILSTASQGIEMFTSDLFGKLTSKMSIDLKEIGFPKSIRFKVNTNLVGKRISIS
                     FLRKENDVIRLIKKYRVKVKALGLCVLNFNEYLQDGDMLDIRYEEEKSRAWYRIEFPK
                     KQANSHDTSLVTKKFKSGKNYSDLEISTLRLKYTDQPTAVFMVIPDYDPSNHVLASIF
                     ISQLYTELASNCKQTPDKKCFRRVHFLLDEFGNMPAIDNMDGIMTVCLGRNMLFDLVI
                     QSYSQLETRYDKAFKTIKENCQNHILIMSNDEETIEEISKKCGHKTTINRSASSKHLD
                     TDSSVTSSAEQERVITVERASQLIEGEQIILRNLHRQDTKRNKIRPFPIFNTKETNMP
                     YRYQFLAEDFDTQRDINEIDIACEHINLSLQDNQIPYARFIKDLKTRLEYSIINNIPI
                     SEEDYQDYLNLSGSQQTINEEELLKLVNTEVKSQDMEGQVLSEQEMKINIYLKESQKE
                     AIELVKVINGRLADENSADMVIKTINSQILDTPFIQSLINDSIAIHNVQESKDQIMIL
                     EQQLANAYELAVFKTKNSILKNKIIKLKNAMTKLAKAI"
     gene            6048..8684
                     /locus_tag="IXT46_000656"
     CDS             6048..8684
                     /locus_tag="IXT46_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946593.1"
                     /translation="MQWLKYKWPIIVSLIIILFMAYPQRVFALPWITDNKEVLKFLTK
                     YQDYLQFTKGGFGSIVVQSLSWGLIRGAYFVCKSAENLVPQSLSLFSFVESSSLGAVY
                     QSVLNTVVVGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALILLMPTMISSGIQ
                     FAKTFYKDSTTITKADGGVAWSLIEDGVTDLVYINKNDAYDRLGKDGVQKNALKEKNF
                     FSYDFSEVITVDTAKDLEDDNKKAEYLQSRLTPDGEGNMQAVKIDDGWMSMFSDSFKG
                     GYYRFTKNTFALTLGLLSLAVAYVFSIFIIVTAILELAFKRVLGVLVFATDIETGQRS
                     KVVLSDILQCYLTVGFQGFGLSMFAMFVSYLGTGGGSSVNPFIKAVAYVCAVFVLIKG
                     SGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGNGNGSDSGEGED
                     RKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDMAND
                     TKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSNRKDGAKVENADR
                     IMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKSAEELINQKRQE
                     AKYTPEAMNREEMLRKRVEGRTGTNTDEKEALTKERIQEAKNSNTGLEKLVKENLQNS
                     TSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIGVRENLQSSSTSQ
                     PKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGFKTVD
                     VRENVQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFT
                     YEDNELFRDTLNDPNPLFDNLN"
     gene            8708..9043
                     /locus_tag="IXT46_000657"
     CDS             8708..9043
                     /locus_tag="IXT46_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946594.1"
                     /translation="MPAFYEVKMMYRNPKNIKQEIKLFFFYLVDLGIVAGSVMASVYF
                     AKLMPISPMMKFALYLLAFVVGVWMCVRTPNHPKERNILMLYYLFKMDRNRYHEVEFK
                     RNSRGKIEL"
     gene            9040..9657
                     /locus_tag="IXT46_000658"
     CDS             9040..9657
                     /locus_tag="IXT46_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946595.1"
                     /translation="MIVAESNENKLSGVFDKFLELVIPKDKDMCELLPYKKILKDGTL
                     VTNDNKYQAFFKVKTTDLTSISEDGFMRMVNKLTYLNRVYLEPYKIYSLTYPTETVNQ
                     AIYWKHRIQEAKRSLLSNNDPNLETYLKWNLKLAYDNYERVDLVSTLPELMFVICVYG
                     KTQKEVKNHADVMKQAGGRELDLQRITEGDLINVITKLMNPNTSL"
     gene            9673..10140
                     /locus_tag="IXT46_000659"
     CDS             9673..10140
                     /locus_tag="IXT46_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946596.1"
                     /translation="MLKHCRKGFCKVIKGKNAADLIFEWKESNLINVRGKNGSGKTER
                     VMASIDNSRPRSRALVITDEKNHYKGIRTIEKKYLTNNDLKVVDDILNIYPDFNLVVF
                     DETIPVTEIKGFYQSFSNLANKYEEVLFVWITEEDSNSKSAFFSEKNAFLHSI"
     gene            10156..12111
                     /locus_tag="IXT46_000660"
     CDS             10156..12111
                     /locus_tag="IXT46_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tra protein"
                     /protein_id="HAQ4946597.1"
                     /translation="MIVSKKLARNLVSEGYDLRLVEKYQPSGGIKFDERYISTGDGYV
                     TSIAVIEFAEDVNSRWLTDIMAIPNTIATFDVCTADKEDLLHKINTSIGELDYRSTNE
                     NRTTDKTDALLDKYNLEDFAQEITKRGEVVKTVHARIFVYSDSLEELEKRISEIRKDL
                     ASVNHKAIVPQFRMKDEWMSLFQDGMEQESKLFAKKGLTVPAKNIGGGIPFHHKSLKD
                     PRGFYLGTTSTGGAFIFDPFYSTKQRRSFNGFILGKMGFGKSTLIKQLQEGLQAKNCF
                     IRGFDKSGEFEGMVKKAGGVYVDLGGGDMVVNPLQIYATVMKKDQFGNDVVDESKSFQ
                     NHITKCSNQIRFLEPEIDTATVREYTLMLQDFYIHYGILPKEWREARDDNERNQLNTN
                     ICNLPNDSYPIYGEFLKFIENQQFKIKNATPERVRSIELIKLIVTDMCTTYPQIFNGV
                     TTMPNFDTTKIVYYNIDSISKMSAPVFHCQLFTALTTIWNSALQNGKIQKENFKKYGS
                     DYYKYAQDFMVLIDECHNVINSNNKYACEYVLSFEREMRKMRAGVYFATQTPEEIIPK
                     DSGSEVADVIRNIFNLCTFKCFFNLDSALLEDIKKVLGNTITDTEIMLLPELEVGQAV
                     VQTSSEDTYMINFDPYPEQIERFDGGQ"
     gene            12133..13269
                     /locus_tag="IXT46_000661"
     CDS             12133..13269
                     /locus_tag="IXT46_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946598.1"
                     /translation="MEQNKNNNVASTLARQGMKQVSKKIGLALKIKIGVVIGLITLVG
                     LLVIGSLATLQGTQTATNTGGAEVIGGNKPLSPEVQKWQKTVEKYAEKYGIKELVPYA
                     LAIMQCESGGKLPDLMQSSESAGLPVNTLQYEESIDQGLKHLSNVYNIAKSYGMESNY
                     DGIVQAYNYGIAYMHYLGKNKKTHTIETAEAYSKNVVAPSLGNTTGQTYSYVNEVSIK
                     YGKTYLYLNGGNFYYAELVKQYIGGGSGNPANPSEFWGKMKTEMEKYQGWPYVWGGKN
                     PTTGFDCSGLTAYLYQFSAGITIDSYTVTQYEATEAVSIKEAKAGDLIFFRGTYGAPD
                     FISHVGIYVNETTMYDSNSSGIGYHNWQDSYWQSHSPEIRRVKK"
     gene            13284..13934
                     /locus_tag="IXT46_000662"
     CDS             13284..13934
                     /locus_tag="IXT46_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAQ4946599.1"
                     /translation="MIKRKNDNKWKYICGVLIIILVLGGLLSQLHTSNIQAKNKKLDQ
                     EVTQLEEQNSKLSKNISDLNANVEANLTNDDGSELNKQIAEVAKKFVELYPVYDIEKV
                     EEKKADLEKIATPSVADSIVPDDMITTSKKTLESKSTTQKGEAYSSDPTFKSKYKDSK
                     LYTNYVNANTINYFAEVNYKTESSSGDTENTVYMLFEVTNKDGQVLVDNYEIKYLK"
     gene            13948..14844
                     /locus_tag="IXT46_000663"
     CDS             13948..14844
                     /locus_tag="IXT46_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946600.1"
                     /translation="MNKKYSIHNKKEPNKKNKAQIDKVYKKTKGVKLYLGAILGFLAI
                     GMIIVFSPYVMGKSYDFETVKMSSAQNVTSSLNMYVDDMEINREAGLFKLVLRYQDDT
                     GTKSLSNIKSDYKLNFITNKNNEDVKTKVVKLSDEYTVIYYQNLPKDFGVISVTVNPR
                     YIYPELEPSNDLKEKEIKFYAVDKDIKSNAKLEVESTSDLQKDNFKYQIKAIENSIKD
                     EKKSIEKMNLANKVVQKDIDKANQNLEFQTLDEQTDTKNEISSMQTTIENNKSSIEES
                     ENKIKQFEEKIKQLEKSASRFE"
     gene            14880..15110
                     /locus_tag="IXT46_000664"
     CDS             14880..15110
                     /locus_tag="IXT46_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946601.1"
                     /translation="MCNSIVTIQEKAEEELMRIEAEYKEKRKAIKRKKNAELKKYKEE
                     QALKLGMMLCKYYDCYDINEVLKKANLNQFCE"
     gene            15461..15757
                     /locus_tag="IXT46_000665"
     CDS             15461..15757
                     /locus_tag="IXT46_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946602.1"
                     /translation="MDVSIRGIDPQYVKEIDKKVNKIQERTGKKFSRNDYFLAIIRQD
                     SEIDLIDYKKSEFDLVVEKLLLSNEQMVESISELTSVYERLFNFLISERSDLNK"
     gene            15754..16221
                     /locus_tag="IXT46_000666"
     CDS             15754..16221
                     /locus_tag="IXT46_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946603.1"
                     /translation="MNYPYFKVSATEDVKEKFNKCFEVNKSVFQTKSNMFRYVVSNLP
                     MLTKANQNFRDPEKEELAKNLEEAKLKISELETIIELQKQQLENFNKKEDSTHKDYSE
                     QLNSIEESVYKLLINSGLASKELEEERAEPEQESSRLGEGTMFSSPSLRFTTD"
     gene            16288..17823
                     /locus_tag="IXT46_000667"
     CDS             16288..17823
                     /locus_tag="IXT46_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946604.1"
                     /translation="MVGDDMTEHIFNRKSASIILKAKFETGKSKKNNHMVELQKFVDY
                     ISRQEAIRQDKLDHDYSEDELNELARIEKALEKIEQETDQPVIKDLREMDKYIDYMTR
                     KKAILENVDNEIVNGAFSNTKRYITKKDISKIKESVIEAKNNGSVMFQDVISFDNDFL
                     VREGYYNPETNELNENVLYEATKSMMGKMQEKEELVDPFWFATIHRNTEHIHIHVTAM
                     ERKNTREIMEYDGVLQARGKRKQSTLDDMIFKFGSKILDRTNEFEKISKLRKEVPLEL
                     KQSVKDSLIQLYVENNSRYDKELVKYLKELKKEIPSTTRGYNELPEETKEKIDEVTNY
                     MTKDNPKRKEYDRMTKEIDELYQTTYGKRYNPQEYYLNRKKDFNARMGNAVVGQIKLL
                     KQSEEKNLKSNELKNLLDGKKLNVKFDREKPEFKTKYAKQSYDDFQKRLEERQLAREK
                     NEVHFKKISEKFKDKKLIRKIDRVINDDLNMYRAKNDYEVAQRMIEQEKMRQAREFEI
                     GMN"
     gene            17845..18174
                     /locus_tag="IXT46_000668"
     CDS             17845..18174
                     /locus_tag="IXT46_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946605.1"
                     /translation="MKNFDIVCSNTKNIYLRELLNSDSETIEDVKKIIVLFEKENMEL
                     ENWGLFEIPISGNYCFYNWKTEDDVAFANYFFDKNYFSPLYIDKHSNEQVASSIKEAI
                     KLERVRK"
     gene            18176..18439
                     /locus_tag="IXT46_000669"
     CDS             18176..18439
                     /locus_tag="IXT46_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946606.1"
                     /translation="MIDFRTVMDKLSNGDFRVLIELYLNVTSTVKEFLYSNPKTALVL
                     VAVLIVFAVISFIKKMIPLLIIGAVLILGLYFPEVLDQIKNIF"
     gene            18614..19480
                     /locus_tag="IXT46_000670"
     CDS             18614..19480
                     /locus_tag="IXT46_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946607.1"
                     /translation="MKKLRVIATIPMIFSFALLLSACGKEEAGAKSNEAHNISFIDSA
                     EQKDSRCWLVVETSSKNKTPIDKNEYVKAVIQTKDGKAKVFKTDMEQLTLEKVSKMSD
                     EEIIEQALNADKQKFNDKKKSDIDSYNATLDSVKTELENEEKQEFQNDQKIADFQDSI
                     PKIQADIEEIDGVQYSEPEWKMVSATIKMDNENKSPSMETVKLSYKYLDSPIWNLNSF
                     GEVSSEGELSYESTSMDLKLSIPVATTKVLDNFYSGYSNDELDQLLLTKVASKDNKVQ
                     LDSKGKNVSIVE"
     gene            19635..21461
                     /locus_tag="IXT46_000671"
     CDS             19635..21461
                     /locus_tag="IXT46_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAQ4946608.1"
                     /translation="MAYKKGNWKPKTKEQKQKELDDLIKASNSKIEQYQSNPEDMIEF
                     AKFMSKIHNYSPLNLSLIDEGFEGAIAVASYDGWKKLGFQVKAKEKGIGIYAHAPVTV
                     FIDENGEEKTLKEATNEQKEKIKNGELRSKKIKHFKKGYVFDISQTNATEADLPKIFP
                     NRVWNFNIDGELSVSQLEKGVNHLAESMNISIKDMNESGRGEMGSARGEYIQYVDGRE
                     EIVLNSRNSRTQNLTTSIHELAHKKLHNKNEHGSSYSTPIKEFQAEMTSFIVCHNYGI
                     DTSDFTIPYIANWTKNNEKIDPKNFRQIMQEVRETSIDFISTIDKKVLEEQQTAFNAL
                     KNSFVPNENKEQIQQKSDLEFHNFYDSTINDPDRTIHGSYLEAMVDYYRGKYGENSIE
                     LTHSNYDVTAKIGENYVTYYSDTKQFDVCDVYGVVFENPSENKHDRLLLDRSPENCDY
                     VEKFVVESLKACENHELKNDTLKLSEPLRSVVINEAVYNLSENANNYYNEKCWQEEIE
                     NQTNINDVKELNSCMTAEDFYESHKQEIENTITDFESVSGTNLRDTIDNESYKEVASV
                     VAYKLVATKVKYEMDEGTFKIPENSNLEKPTVKTAERSFEME"
     gene            21469..22542
                     /locus_tag="IXT46_000672"
     CDS             21469..22542
                     /locus_tag="IXT46_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946609.1"
                     /translation="MSNEQNYETGGTYRLFHGSMNKFDEFSLDHKGLNGTANGFGVYL
                     TPNKEMATMYAEQGSNGNNGFVYEVNVELEKPISMNERTITDEELSKVIDKLQESNDI
                     LNDYNDVSYYGEKVVKREVIASLSENENDVDLINDIGNTIGDHEATAKAFYDVGKYTH
                     IIAEEQLRQKDVVIVVLQPDKVKIETIHDLNEERNSLESSEDMTDKFVGHKVSEVPIR
                     EVVIKDFEQELETTNYYDKQAWQERIEYLENMEEPVSRLALDSDINEFYDSHKEEIET
                     KLTNLSEKLEIDKEELLGFPVDTSSTEYKKATSIMAYNGAMREIYNEIENDTFEIPPV
                     SEEMENKILKLTNFENTTKFEME"
     gene            22551..22811
                     /locus_tag="IXT46_000673"
     CDS             22551..22811
                     /locus_tag="IXT46_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946610.1"
                     /translation="MIEQENRNFLETQGEYRQINNSHFVICEDVQIAFKMALKYGKSI
                     RKKIIREKKSKKIGFWELSLRDGLNFIFCTEDYYEKYKCTLS"
     gene            22873..23559
                     /locus_tag="IXT46_000674"
                     /pseudo
     CDS             22873..23559
                     /locus_tag="IXT46_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362787.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3991 domain-containing protein"
     gene            23584..23940
                     /locus_tag="IXT46_000675"
     CDS             23584..23940
                     /locus_tag="IXT46_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946611.1"
                     /translation="MNDTIAILSDSLIDLDKTSTDYMIIEEQLKNKNPEFDIQEKSLR
                     IELPKFKQKKLITILFEIIERYGLTYYQIWTDKKDGQYTKGVSIEAVREDDQVSIKAV
                     QPLMGYNEELLNCLNV"
     gene            24102..24293
                     /locus_tag="IXT46_000676"
     CDS             24102..24293
                     /locus_tag="IXT46_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946612.1"
                     /translation="MEQTRMFWSDRMQDHLDCIYKTREQLNKLDTVRYYFTYFSENDE
                     QRWDIFHDGNYEEFFYTES"
     gene            24402..24620
                     /locus_tag="IXT46_000677"
     CDS             24402..24620
                     /locus_tag="IXT46_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946613.1"
                     /translation="MVNKKETFKVGMEVQGVVIGSGELIEGEVISLLANVAVVKAIGK
                     APVVMKKCSMMCLDGLNNPITQRFENVI"
     gene            24657..24974
                     /locus_tag="IXT46_000678"
     CDS             24657..24974
                     /locus_tag="IXT46_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946614.1"
                     /translation="MKDYASRKFIHLEPMKELVINGNEYNDYKSLFVKEQPKGGIRMK
                     NLPDFRFIEVNNLGIIEDYLDKLDEAIKQSIEKNGEDHILTVVLKDLKDRLEAEAEYF
                     NKD"
     gene            24985..25182
                     /locus_tag="IXT46_000679"
     CDS             24985..25182
                     /locus_tag="IXT46_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946615.1"
                     /translation="MRAMTEAVKELKKMYPDVLNMTVDDFHEALKNAESEEERTFYLT
                     LSSFVTRVDQKKVINQKDFKI"
     gene            25179..26147
                     /locus_tag="IXT46_000680"
     CDS             25179..26147
                     /locus_tag="IXT46_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAQ4946616.1"
                     /translation="MSLENEKPYYVVVGGVNGAGKSTIYQVQNLKRKELDTDRINADE
                     ILRSFGGNWKKQADINKSMREVLREIKGHFKEGKSFHHETTFGGNPYPDKMRLLKAKK
                     LGYESFLIYIGLDSPERAIERVKIRVAKGGHGVPEDLIRKRYEFSLRNLAELEKYFDN
                     VSIYDNSDEFSYIYVKENHTVVANNTQEYAWVPKAIQEKNAETPISKQIMMDISQEEM
                     NPKETLERIYSASDDFISDRFSKEAQVDDFYRNHKNEIKERILSISFSTGVSQDELVG
                     QDKRRNSCKLAYINSVGELLVKTDSELLSMELNRDRNIQKTDFEVE"
     gene            26391..27563
                     /locus_tag="IXT46_000681"
     CDS             26391..27563
                     /locus_tag="IXT46_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946617.1"
                     /translation="MTKKIEVYVDGSQEERDSFFGFFWKNSREYVKALNMVYKQLMFE
                     ELIENSIKELDHEYIKRELSLEERIDNLLSNEVIDQKKLDKTKRELSKLRIAKNKEAR
                     DVLTQAIGLKSQTRIRDIAKKLDFDYSDFIDSAKMKASKDFSNDFVGIVTGQRTPRIY
                     RNKNKYGLLPFRGRDIKIHKADKFYISLPKGFRFKVNLGRKPRKARDSALTLERIMDG
                     QYKLNQSNLIFEGKNLFLNLTISFEKDYHKLDFKEGAELTIKFTDLCSGKCLVNNQSV
                     IDFGDSKYISNFKNKIKAMKSREQSRGVFSKGGHGRKRKLDQDRWEAIKKRESNFVKT
                     YNNQCSAKIIQTAIRNKTQIICISEPDKNYGEWAYYQLKEQIINKGKRYGIEVKSE"
     gene            complement(28123..28500)
                     /locus_tag="IXT46_000682"
     CDS             complement(28123..28500)
                     /locus_tag="IXT46_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HicB family protein"
                     /protein_id="HAQ4946618.1"
                     /translation="MKKSYPVIFSAEENGYSVVFPDFAGATQGDNFEEAMSNAKEFLD
                     GILAYYIDEDISVPSPTDIHQLNNLGNNKIVSLIQSDPSPFIQKKTVRKNVTVPEWLV
                     ARGEKDKINFSKVLTDALLKIYE"
     gene            complement(28546..28734)
                     /locus_tag="IXT46_000683"
     CDS             complement(28546..28734)
                     /locus_tag="IXT46_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HAQ4946619.1"
                     /translation="MPLTGKKMLKLAKKNGWKVVRITGSHHIVAKEGFPPVPIPVHSN
                     QDLKKGTEQKLLKDLGLK"
     gene            28905..29447
                     /locus_tag="IXT46_000684"
     CDS             28905..29447
                     /locus_tag="IXT46_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4946620.1"
                     /translation="MKFGGHFLNKKQDQEYYIEKLEKENLELKERIRYYETKFCKRGD
                     CMKPNPVETGKRIKSIRSNFGMTMEQFADLIGNAQKGNINNWERGFSLPNKERLIKIA
                     ELSNKTIDWIKWGTLEEYITSYLIGIGYELYIKDFPEIPHKVFKDIQEKYSDTFSLDK
                     DYELLDSIIKNIFTKYYSNG"
     gene            29642..30538
                     /locus_tag="IXT46_000685"
     CDS             29642..30538
                     /locus_tag="IXT46_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4946621.1"
                     /translation="MEINLFEAGNRIKQIREKHGYTMADLGKLVDANSPSTINNWEKG
                     NNLPNRKRLEKIALLGGTSVEWIKYGDFSDYVYRLTQNIEEKILKEYGETTLNNYREA
                     LLDELTIEKITYEEDTKILAAAEKINTQNIFQEVKYMYSPDEDYRNIEVKPDLGLTDD
                     NKNIKMIGQRIRKIRKKENITLEEFGKLFSPTADKAVISNWENGKNLPNSERIKKIAE
                     IGGVSELYLMTGVDSSVAESMYFLSEVALDALERLSIEEVNRIIESFAGYLNVISKID
                     DPDKREISLNAICQLSLLDKMG"
     gene            30587..31969
                     /locus_tag="IXT46_000686"
     CDS             30587..31969
                     /locus_tag="IXT46_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4946622.1"
                     /translation="MKPNLSLTSERIRKIIESKGLTLERFGDLIGDTPISSVNNWLRG
                     VSLPNKNRLLTIANIGNTSVDWIKWGTLEEYIASYLIDSGYELYIKDFPEIPYKVFKD
                     IQEKYSDTFSLDKDYELLNPIIKFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTT
                     LTNYYRGERNPRNTETWNILADYFHVPVSYLMGLDETNVELKNLNIGNNIKNIRKSKN
                     MTQTDFAELMGLSRSYIGDLENNRSNPSIKTLEAIARALDVPIVALINDSSTDNIVEP
                     YESLTAENILLKQENEELKYEVESLRKRLYEIQQVVNQGAEKMIPNLKDVSKRIKYIR
                     KKLGMTMEQFGSHLSNSPKSTIATWESGRNIPSQKKLQLIAIVGETTTDWIKWGTLEE
                     YITSYLIGIGYELYIKDFPEIPHKVFKDIQEKYSDTFSLDKDYELLDSIIKNIFTKYY
                     SKEFEVTQIP"
     gene            31983..32765
                     /locus_tag="IXT46_000687"
     CDS             31983..32765
                     /locus_tag="IXT46_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4946623.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDPKKVGRKIRSIRK
                     KLGLTMQEFGYEVSNSPRSTVSTWEHGGNLPNKAKLKKIADIANCSVEDLLFDEGFIS
                     EKSQVKLINELKEENSKLKEKIKYYECLFDGIESLLNSRKNS"
     gene            32805..33416
                     /locus_tag="IXT46_000688"
     CDS             32805..33416
                     /locus_tag="IXT46_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4946624.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFRKIGVEKVFAEKKSGRNTVERP
                     EFNKMLSFVREGDTLVFESLERLGRNSDEILETVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVINIFSWTAQNEREEIKRKQKQGIAIAKKKGVYKGKPYEYSSTAKNPQ
                     KRFIYNEIVRMLGEGVPIKRIAEKTGTNRNLVYRIKKRISESD"
     gene            34664..35227
                     /locus_tag="IXT46_000689"
     CDS             34664..35227
                     /locus_tag="IXT46_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946625.1"
                     /translation="MTAIYKALKNSNVSEYVKSRVLNNNLDYILENGVADLISKLSDP
                     IDIDHLVVWQDGTLEVSIYGEFYSRNKVTTFKNSISGREDLKGINKNSKFYRTNKELL
                     EKISKRVFELVNPFSKTRSKELFGIFYDGFSAKSNVEKFFYFNDSAYIAVKDSKRIPE
                     ATLEYLEPIKLSVFYSLYEKEIADEAV"
     gene            35214..36098
                     /locus_tag="IXT46_000690"
     CDS             35214..36098
                     /locus_tag="IXT46_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraA"
                     /protein_id="HAQ4946626.1"
                     /translation="MKRFKGSRMSKKIGKESLSLGLKKEIFKFKNMYSEPEFRLIFQL
                     DIVRGLKISFSCLGYLVWLFIARVGWSNAYSFYKLFAGTDRLKESLEVKEALNILGSL
                     AFSLFIFALFILQVGKIMMSTNDNYINYLKPFQKGIKIICRQGTVLFLLSLYEHEIHF
                     QNYYNTTTKLGAFLLLYLVSNIAEKMLFKHIVKQVFSDIKKESYCLKTPYGNLKNVEL
                     FLFKMDSKWDKYIYRSKEVFLTGSYNETLQESLYDTGAIFNNEPMVLKDFFGDYELVW
                     NPKQLSEQGAENEFAEVH"
     gene            36595..36849
                     /locus_tag="IXT46_000691"
     CDS             36595..36849
                     /locus_tag="IXT46_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946627.1"
                     /translation="MYNVGDQIDEIVKIGNVKLDKSKYCISETEIIFNTELGYILIWK
                     LPFPKDEETLKKINTLKIRYCVYEVIDKNTYVINQVKVMG"
     gene            37245..38846
                     /locus_tag="IXT46_000692"
     CDS             37245..38846
                     /locus_tag="IXT46_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAQ4946628.1"
                     /translation="MLNSCEYADVLAKILKNGIKQFNSKNLVAFKKNSNKIGAIAGFT
                     SKTNMIKTKGLIYRSIDRVLEDSDVLTHWTPNVYSWLGGGENKTIFGHKEANLIQINT
                     FVADIDYPVGEKKTDLNLLVLYLLEEGLLPTLIVDTPKGYHCYFLIQNYNQETDSFDK
                     ASYISNSNDFKSLRVAKRISENIRKSIQNRLPQVDMGCNHFGIFRFPTKKNIVHYEPN
                     FVDTFEGYLKWSKDFEEKEYALKRSNLSLLAPNSTGKKGSKRQIDTKWYDFLIHTDIA
                     EGDRNKTVFTLALACKSSGLSIGECMDQLDQLQFNNDLSYSEVERTIRSAYRGDYKGA
                     KSSYVNEIIENYATPTEFEKYSINVNRQAVKRKGNRVDPSNWVKFAKPREERKYSHFE
                     ESKADLLAYLERKQRSLKKNELFLSVSMGTISEETQIPVSTLKVILKELRTANTVILQ
                     TSRGRYGSTKIATSKFVEAKILSTVIQNKKDKQVFVLELLGTANSHVETILRRYEDKT
                     VPFHANILKEREKSKHAPIRGANTG"
     gene            39080..39379
                     /locus_tag="IXT46_000693"
     CDS             39080..39379
                     /locus_tag="IXT46_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAQ4946629.1"
                     /translation="MVIKKYVYSHPINVFIIGKLGLSVEVFCELYGFKQGTLSSWITR
                     EREVADLPISFLYALSLASGGNMNEVYDCLCEYEKEYKEYLKISAPKRNKKYIED"
     gene            39514..39873
                     /locus_tag="IXT46_000694"
     CDS             39514..39873
                     /locus_tag="IXT46_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HAQ4946630.1"
                     /translation="MNIDGIYNESDFKKGDIAVIRSEYDFPSEIGIHTVEGKTVCRYW
                     GRKGNLILLLDTDSGDKLKFCFWHNTNYCCEPIPKRLIDVDKESVRYLADGTRIRLTY
                     QKSENASITRVRDIVVI"
     gene            39890..40108
                     /locus_tag="IXT46_000695"
     CDS             39890..40108
                     /locus_tag="IXT46_000695"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946631.1"
                     /translation="MELIPYAYQHLYKAKSMKDGNEVVGALICCPPFSYIATIESMKK
                     MCVDELNDGEVKNLKLTRVLERSIEEFR"
     gene            40123..42486
                     /locus_tag="IXT46_000696"
     CDS             40123..42486
                     /locus_tag="IXT46_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HAQ4946632.1"
                     /translation="MATVILAEKPDQAEKFAFALADKKIPKSGGKFEFQSEVFGDTIV
                     TWGIGHLVGLSMPEKYEWLPNKEKWDLANLPFLPKMDELKYEVSKGKSQQFAVVKACL
                     ENADQIIIATDPDREGENIAYNIFKLCKQSIFKKPMKRLWINSLVKSEIIKGFKNLRN
                     AEETISFFEEANARQIADYLVGMNYTELYTLKLQQKGLSGVVSLGRVQTPVNTLVVEN
                     DLSIKNFKSEKYKVIECHTVDREPKVIFKNSREYFNLDEFEADTKKYGLDSASIGIVK
                     SVEKTLKQVEPQKLFSLGGIQEYANKKWKYSAKKTDKIIQSLYDRGYLSYPRTDSELI
                     TTNEFEYLKANLDVYKSVLGISIDTPCLEPKKRFVDNDKVLEHYALIPTMDIPDIANL
                     TLDEKNIYEIVTRRACLMFAEPYKYENTKVTLDVNGLEFTTSGNVPISLGWKQVDTNL
                     DESDDKEETLPKFHEQETINIDIRFIDKLTKEPKRLTEGKLLGKTGIMAKLGLGTPAT
                     RSNIVDTLLNREYIKIENTNVYPTPKGYLLWDLTKNKDLLIGKPENTAIWEESLGKIA
                     QGSYTQEAFLRNIYNYINKTVSDLKKVEFTSDYLEKTVNQNKFDIGSYQVEEKKKVYS
                     ILNITSGEQFVIFKNISGKAINKKVLQELLLNNRTDKVLSGFKSKEGKAFNARLLFDP
                     NVMKVVMEFEKNSPKGDKKSKHDTVNGYEIVEKAKVFEIKELATGESFIFYKNNSGKT
                     LSSKTVKELLENGKTKEKVTGFISKDNKKYSAYLVFDNKNKVIKKEF"
     gene            42804..43403
                     /locus_tag="IXT46_000697"
     CDS             42804..43403
                     /locus_tag="IXT46_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946633.1"
                     /translation="MNLKNTNSNKSTLYVISDDYINKLKKVDYRVQNNYREQRLYFKS
                     NLKISNKNEEINYYVPLASAKENQRSLTNKSVFKIYGDREEKDFLGVLHINNMIPVPK
                     DCAKVWTPNSPNVDEKYKMLVIKQAKYLKLHESEINESCELLYNSKLGKLDPSYFKKN
                     RKEVITYQKIMTNVESLEAVSIAESQRNIHVQTQSIDVE"
     gene            43515..43739
                     /locus_tag="IXT46_000698"
     CDS             43515..43739
                     /locus_tag="IXT46_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946634.1"
                     /translation="MISMARPRKYNTEEERKEAMKKARKKWVEKNQETIAYIRAKSFA
                     KKFIEMSEDEDIELLEKWLEDRKNNGQNDE"
     gene            44091..44327
                     /locus_tag="IXT46_000699"
     CDS             44091..44327
                     /locus_tag="IXT46_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946635.1"
                     /translation="MLSDYKEELKLIENRVLGFVECKDNLDDTLEVLESIIFNTKVLD
                     LKAINGDMTTHIILDEISAKEIGETLIAWANKEL"
     gene            44407..45261
                     /locus_tag="IXT46_000700"
     CDS             44407..45261
                     /locus_tag="IXT46_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4946636.1"
                     /translation="MMKSNFLGYVIAINMFKGGVGKSTLTQLMADILSARGFKVLVID
                     VDPQGTVTKKFQRQYDLKVVGKMTLFEAVINMSFLDCISPVKENLDIVLGSEQMSRFT
                     KVLRDMWRSTGFTDEGEEVFWNLFNYMIGNDNLRDQYDFILFDTIPTVSEFTDNVYVA
                     SDFLVIPTQTEQDSIDNLHSTVTNYQTAVKEVNGDLEILGIVPYLVDTKLKTGLELLS
                     ELQEEYGDLVYSHIVSERGVIKRWGREGLNKSIPHSKTAYSMYVDIVEETLVRLEKAT
                     GENILERV"
     gene            45274..45711
                     /locus_tag="IXT46_000701"
     CDS             45274..45711
                     /locus_tag="IXT46_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946637.1"
                     /translation="MMSKTKKVTSAGSNGSGNPFGIKSGSGGFNIGQQMLKGKAGIKS
                     TGDKRKSVRVPVELYDEVVKDLSYGAKYSLMTEILALFLKEFETHGNSIVTDFGKLKT
                     RPVKISEEAFKVLKVIKFETDQSNTNIIASALTWYLDKRKGKA"
     gene            46031..46474
                     /locus_tag="IXT46_000702"
     CDS             46031..46474
                     /locus_tag="IXT46_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4946638.1"
                     /translation="MQILEDIKIYWKRIIGYTLVLLVVNLFLSMIALVFVNQRKDNVT
                     ELVTFISFFISGIFAPFFEETLMRGIIQNQLELKTNLSTRSIYIIVAILFSLSHLNLY
                     FIPYFMTSLILSFVYDNSDKRLIVPVTIHCFYNLIVILLSVVFYT"
     gene            46619..46942
                     /locus_tag="IXT46_000703"
     CDS             46619..46942
                     /locus_tag="IXT46_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946639.1"
                     /translation="MARSRIAKIEQTKKDKKISKNKTKFFKAEDVKRIAWSVKTFDED
                     RYVKVSMNGLFVQLGNFSNFKTIDELYPEIRNIVDSKGLIVAKRKSRNSGLAYCKNKG
                     IMIPA"
     gene            47360..50989
                     /locus_tag="IXT46_000704"
     CDS             47360..50989
                     /locus_tag="IXT46_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946640.1"
                     /translation="MKKLKLISIALFSLITMSTARQSIVSAEGTSTKAVVEESGDKKV
                     AIDDKVKNEAEKATVVQGADGLMYVVVDENDPEKLLEAESPLKNQQENTGAVEVGVDE
                     KRQEKADKANEKVKNFDDIDYNDISSLQSALNDPKFPFLSEDELNEKLQKTKNTFESE
                     ALMKKTRGYFSQRILELSNNLNDVPKRAKVSRHALVSNRASQVSETRINPPNGYPWVI
                     YLIRSNGYSYTENYAIRRTIDGKEAFCLQAGVQATNTYTGSTSGYLSNSQREMISSIL
                     SAYKELGGWANNDAGKQRWIATQMLVWENSNEKPKSITVTPNWKNGATKWKNDLVARA
                     NAIRVRTKWDSTSKTVDEGDKATFKVTNTYGDHNLHVKSVSGGGKATISNGTLTVDTT
                     GATGNKITVDMIKGSHPSDAHPTTVWSNGSYQKLVTGSFYISTSVTVNVKRKGTVEVL
                     KVDSETKKPLSGATFRFSYSGKTKDVTTDSNGKAKLTERLKAGTVVKVKEIKAPNGYQ
                     LDSSEFSITVKENQNVTTTRTNKKSTGSVEIEKIGDLDGLGLPNVVFTIYNSDNKVVK
                     DNLKTDSNGKIKVDELQFGKYYAVEKQGVTGYDPDGKKYNFEISQDTPFTKPAKVKVT
                     NIYEVSISEKVSDMNESQVLKNNWSADPNDYLQYDITTGNLKKSGERNVQSFIIEGFY
                     DNKNVDVSKSEVYVGSTNVTNSFDINNDTNNGKVIAKAKTSVLTNNDFYNKSYNLRIT
                     MKIKKSTLENTEKQKNLTIVKNSKVTVGSKISKSASSNDVETVLYSRKVTINHIDEKD
                     KHLLKQDIDYKYDGETYEYKPRTDLFDKDGNNYKSDVIHKGKIDGKDIVLNTPYHIPV
                     LSVNVDRIQIDTARAVKNGYLPTKIELSKKEEYEKELEKIVFKVKITDIDNNKVVYDE
                     NFKYKEFNSHMSLDLPTEYLTKNKKINYSVDILLVDNPDKNKFETETKDLRTIGYTSS
                     EKVLTNKDMTNNQVNYSAVVRTVKERENNNPVKEFNESINYKFTDSTKTKTGYGISVD
                     LEPTYRNEIGKQIDMKVYSYPMNELIDSKIDEIYQSGGKETEVKMDRLKNDGKVESGI
                     STQNLSFQFPHMNIERKTGNIYADSQRNDESIKYELIDGGRKLYVPIWCDLGNYSIAI
                     KSSNFGGNYISLDMNQNIDVYAYMYATIDSETKKDDELLLEPVYPESTLPDGWSKNEI
                     DWLNK"
     gene            51049..51411
                     /locus_tag="IXT46_000705"
     CDS             51049..51411
                     /locus_tag="IXT46_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946641.1"
                     /translation="MRVQSYGNSVFDVKREFQDSRRKTKKLIAYFILSAIVFYIVKFV
                     LELNSIVFTDMVHKMLNGEPINFNFDYMLEKAQSNQIVAFIVSIYYFIEKSIFSLKDF
                     FFEMLTKLTTFYNKISKN"
     gene            51645..52067
                     /locus_tag="IXT46_000706"
     CDS             51645..52067
                     /locus_tag="IXT46_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946642.1"
                     /translation="MIYVAFFLDGSDVMLRDMPKMILLMFVGFFLILVIAYYSLNGYT
                     QDSSVKGMQETLRTTAIANRDDSIRVEKGRFALIKSDFEKDFKEKFGKSKNLNNETAD
                     YKFDYLTDGKDGIKAIKVKVESGSKEYQATCILNVAND"
     gene            52079..53494
                     /gene="cpaF"
                     /locus_tag="IXT46_000707"
     CDS             52079..53494
                     /gene="cpaF"
                     /locus_tag="IXT46_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAQ4946643.1"
                     /translation="MRVVEEKKISPKIEETPKSKINIASIIKKNGIKENSEAIEGNLD
                     FLTKLLEEDSGNYEPPIEDAKLNMIRDDLTRNYSQEVLQALTDDEIRRKLVQVVLKEH
                     GTFFKKDKEVAEYVVRECIGTGIIERIMTNDEITDVGWNGSQLSIETNSNKWLFDGDK
                     LNITQEYIERVISKYAVVNDRAFNSGNPIMDGMFKNVRISATHIDNSPDGSTFSMRVA
                     RPRLALNKENFEDFAPDYILELFEKMMKTKANICISGETGTGKTELQKLLLSFIDNHD
                     RMIMIEDVQETHAKELFPDKDIFSWITTPKKAISDLVKASLRNNPRWIIVSETRGSEA
                     YEMLQAVLSGHYVVTTLHAVNARAIPRRFVNMCASGFKINENAVEEDINRYFDFGVHI
                     KKTVVDGKVIRYLNEIVEFSASEPTTVFKQKFINGKFVIENGSLSEDFKEKMAEKFIT
                     FEFPEDQTNTEESLPEEEEVI"
     gene            53511..54326
                     /locus_tag="IXT46_000708"
     CDS             53511..54326
                     /locus_tag="IXT46_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946644.1"
                     /translation="MTKRKGLMDVSELNAYQVAYGKPLDYRDYLNYVGLPCLFMGGFS
                     FALCYYWWIALICGVIGGVYGFKVIMPKSIKRSYELKSLQERNKFINNMTQILTDDSK
                     TVTRALSIAKQRTKGELREDIQILESRLQGADKFQIAEAFREINNKYYSDVVFTQYFE
                     QLETAIYEGRNNSDTMKQIKSYHNDVKRKTEGFMKIKDGYLQDMKQMMFIVAVFIGAI
                     TFAFGFSTFYEGFARSPIGWVFGSIYFLIMVSFMKSFFKHYFDDEIMSLGVSN"
     gene            54326..55123
                     /locus_tag="IXT46_000709"
     CDS             54326..55123
                     /locus_tag="IXT46_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946645.1"
                     /translation="MKVKALKKKRKSSISPLKITKTEHKSFWIKLLGDVYYQKLREMN
                     NSNIAIIKWQKQRLKKSLIFILVGFLMYLFLGKEWYYLAGGIATSVGFYVWQAKSING
                     IYNQFRFERHLQFSKFTRLLIPYLKQKKDGGNLYGVFAKIVKRLDYDTDKKLLMKLMQ
                     EMTDQPNDIRPFTEYAEQTSGTDMSVLFMSTVYDIRQGSADLDVIEELDRLASEELMA
                     GIDSIIDYKSRRFVFFPTKIAMTSFILVVGFAVGVLFMNLKDINFGQ"
     gene            55141..55503
                     /locus_tag="IXT46_000710"
     CDS             55141..55503
                     /locus_tag="IXT46_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4320 family protein"
                     /protein_id="HAQ4946646.1"
                     /translation="MQEQSVMEIIKWFIGLMMIMAMVSIGLFCVQLQDINTFKQQVNY
                     QIERKGGLTTEAVEAIDKYSATNYDRRFTIESDKLNQKVSYGEEIDYTIKATIPIQIL
                     PLPDVTLSFNGNSVSQIR"
BASE COUNT        21572 a         6833 c        10646 g        16677 t
ORIGIN      
        1 aaaaaaaaaa gaaaaaagaa agtagataaa tttacggaaa tgaccgataa aatcattgaa
       61 aagaaaggac ttaaacctaa agactttgac cgtcaagcaa tcaaagaagc acgacaaaaa
      121 ctgtatgatg attttgttaa agaaaacata tcacagcttt tagactaaca tttaggggga
      181 aataaaatga aaaatttagt tatcagcaag tttgcaatgt taccaagaat ggattttttc
      241 gataatgtaa gtaagtttat gtcaaatatg acttcaaaac tacaaggaat ttcactatct
      301 gtaattatct tttgtattgt ggttactggt ttgatgtttc ttttcggaga agggccaagt
      361 cgtactgcta aaaaatggtt aacttatatc gtgattgggg caataattat cttcggagct
      421 tcaactatcg gacaaacgat caagtccgtt ggtggtttct aaggggaagc ttcttagaac
      481 taaaaaattc gcaagtattg catgaaagag cattgagtga ttaatgctct tttttatttt
      541 gaaaaactat aaactaagga gatttaaact atgaaccaac gattcgaata taattttgaa
      601 gatgtagaac ctaagttact gaaaaaagga aaaggattaa aaaagaaaaa taaatatact
      661 ctcaaacaag cagaagcatt agtaggatgg attcaacaca attggtcaga caagacaaca
      721 attaccttga tctgttcaga cacagaagaa ggaacaaagt atgcttttga tggaattgaa
      781 attactccat tttcgattgg cggacaagaa aaattattgt ttcctgatat tgaaggacaa
      841 attttacaag cgccggacag catgatttcc gatcctaata aactgatttt ggatattaac
      901 gatcaataca aacacgaacc agacgtagca gaaccaacaa aagaatcaaa gtcaaaatta
      961 aatttgaagc tcccttcagt agtattacca tttgctaaga agaaaaataa acttatgaac
     1021 gaattgattg aaccagaaga aacggatatt tatgaagaag aattagaaga acaagaagag
     1081 atcgaagaat tagttgtgtc ttctgaagaa acagaagaag tagaagaaat tgaaactgtt
     1141 tctgaaaatg aagaagaaac agaagaaatc tttgactttg aagatgaaga agaagtggaa
     1201 aatgtacaga aaggcgatct atctacaagt agtcaaaatg ggttggaagc tgtaaatgat
     1261 ccacaagttc caccatatat atcttcacaa actcccaatt actctccaca gtatcaagcg
     1321 cctaatgtct tacaaccatt aagaaaacac gaaacagtgc agttagttac gcttaaagag
     1381 tactgtgatt tgggagaaga aattgaaact tcaatttctc aaatggtcga aaagttgaaa
     1441 ccagaatctt tattcaaatt catagggatt ccttctacag gtcttacaaa tactcgtatt
     1501 gatgaatata gaagtaacca tgctatgttg cgattagctg aagtaaaatt tgaaaattta
     1561 agagagcatt attcacggca aattatttct tttaaagcag aagccctaga tcgtttaaga
     1621 actgcggtag atattgcttg gaagaagcct tacgatttag atgtgaagaa aaacaaggcc
     1681 gaagagttat caaaaatgga agcagaagca gaagctaaat taaatgagtt cgtgaaacgt
     1741 caggaaaaca atgtaaatga taaaatcaaa aagtttgaga tcgaacaaga aatagattta
     1801 aaaaacttta ttgcaagaca agaggcagat aaagcggtat ttattgctac agagaaagat
     1861 cggactcaaa atttaattga ttctaaagcg gaatcaatca atgcagattt acttgaaaca
     1921 aaagataaat ttattgatga agaaatgtac aaaatgaaaa ttgaaatgaa caaaaattta
     1981 tttgatggca agcaaaaaat taaatcagaa ttggctactg aactcgctaa ggcaaatgat
     2041 aatgtttggg aaaatgcgct gaaatttatt caagaaattc aagatgaaat tgaagctaaa
     2101 acaccaattt gggctgctga aatcaaggag tttaatagtt tagaagaaca agaacatgaa
     2161 cgtatgaagc aaactaaaga acttcaatta aaagaggaaa gtattgaaat caagcgtttg
     2221 gaagctgaaa tgaatttgaa gcgtatggaa gaattagatc atgaaaataa aatgcttaaa
     2281 attaaacttg aaactgccct ttcaaaaaat gagttattag ctatggaaca agatacaaag
     2341 caagtggtga atggatcaaa cagagttggt gcacttaatt tatttagtaa acgttaaagg
     2401 agaacggata tgagtgtttt taataataaa gttatgttag ggaactgtta tgtgaaccac
     2461 attggttttt acgatggagg aacatacaga gttttattct tacgtttatc tgtttttagt
     2521 tactcaaaag atggaaaggg gcattatgaa aatattaatg cacaaatttc ttgtccttta
     2581 gatagaaatg gggaaaccac gactacaagt agtcacccta aagccttgat gaataaattt
     2641 atctttgaaa agttggatcg caatttggtt gaggggatga agataagtat tcatggaaat
     2701 attcgtggaa cagaacaagt gcttcttaac agtggttgga aaaactttgg tcaattatcg
     2761 cctttagaaa aagaagaata tcaaaaaatt cctaaaaatg aattagtaac aagaaatcaa
     2821 acatatatct atatagaaga ggtaagtatg ccagaaaaag aagaatttag aaagtctcaa
     2881 tctaaggtaa caaaagaaga tgtggaagtt gcagaaccga atcaagcaga tgaaatttta
     2941 tccgatgata ctgatccagt gaatgatgaa ggagaggtta ttgaagtttt tgaagctgaa
     3001 attatcgaag aggaagaaga aattaaaagt tttgataaaa gaatgtatcg agagaaacca
     3061 aaaggttatg tgaattttga agatatgtat tatgacgaat attctaatga accaccgatc
     3121 aattagtggg ggtcaaatat gaagctagta caaaacaatg aagtgaaaga aataaaaaac
     3181 ggctttgtta aaaactcgaa caaaattttg ggaaagctga aaaaagtagg tagtttcaaa
     3241 aaaaataaat atcatactgg aaaaattgag ggagaagatt taccaaaaag tttacaagat
     3301 aaattgaatg ttccgcttgt atttataggt gtttttttag gttcaatagt ttttctagca
     3361 ataacgtact tattgaactt tttaaaagct ttgttagttg caatcggaca gtcagaaagt
     3421 gggctacttg gtgtagagtt cgatcctaag tttagtttgg catatctaaa accacttggg
     3481 gatacgaaac aatactttat gtgtgctgtg gttgcggtaa taggagtcgc ttatttaata
     3541 tatgggaaat taaatcatga aagtgagaaa aatcttgttt acggtcaaaa aggagattca
     3601 agactttcaa ctatcaaaga aattaagaga gattaccatg agataccaga aaaaacagaa
     3661 gtgtatgatg gtattggtgg tgtgccaatt agtcactatc aagataaata ttatattgat
     3721 agagacacag taaataccgt tgttttggga gcttcacgat ccggtaaagg ggaaacattt
     3781 gttgttcctt tattagataa tcttagccga gcaaaaatac aaagtaatat ggtcgtgaat
     3841 gatccgaaag gagaattgtt tagcgcttca aaggaaacac ttgaaaaacg aggttatcgt
     3901 gtattagtgc taaatattga tgatccactt gaatcaatga gttttaatcc tttacaacta
     3961 gtaattgata gttgggctaa caaggactat cacgaagcta gtaagcgagc gaatacttta
     4021 acttcaatgc tctttgcttc aggaatgagt acagataatg agtttttcta taaatcagct
     4081 aaatcagcgg tcaatgcgat tattttaacg attgtagaac actgttttaa caatgattgc
     4141 attgaaaaaa ttacaatgta caacgtggct caaatgctga acgaattagg aagcttattt
     4201 tacactgatc caaagactgg aaaagaaaaa aatgctttag atgaatattt caatacttta
     4261 ccacaaggga atcaggccaa gattcagtat ggttctactt catttgccgg tgataaagcc
     4321 aaaggttcga ttttatctac tgcttcacaa ggtattgaaa tgtttacaag tgatttgttc
     4381 gggaagttaa caagtaaaat gtctattgat ttgaaagaga taggctttcc taagtccata
     4441 cgatttaaag tcaatacgaa tttagttgga aagaggatta gtatttcatt tttgagaaaa
     4501 gaaaatgatg taattagatt aattaagaag tatcgagtga aagtaaaagc tttagggcta
     4561 tgtgttttaa attttaatga atatcttcag gatggagata tgttggatat acgatatgaa
     4621 gaagagaaat cgagagcatg gtatcgtatt gaatttccca aaaaacaagc aaatagtcat
     4681 gatacttctt tagtcactaa aaaattcaag tcaggtaaaa attattctga cttagaaatc
     4741 agcaccttac gattaaaata cacggatcag ccaactgctg tgttcatggt tattccagat
     4801 tatgatccgt caaatcacgt acttgcaagt atttttatca gtcaacttta tacagaatta
     4861 gcaagtaatt gtaagcaaac accggataaa aaatgtttta ggcgagttca tttcttgtta
     4921 gatgaatttg ggaatatgcc ggctatagac aatatggatg ggattatgac ggtatgtcta
     4981 ggaagaaata tgctttttga cttagtgatt caatcctata gtcagctaga aacaagatat
     5041 gataaagctt ttaaaacaat taaagaaaat tgtcagaatc atattttaat catgtcgaac
     5101 gatgaggaaa cgatagaaga gatttcaaaa aaatgtggtc ataagacaac aataaataga
     5161 agtgctagtt ctaaacattt agatactgat agctcggtca ctagttcggc agagcaagag
     5221 cgagtaatta cagttgagcg tgctagtcaa ttgattgaag gggaacaaat tattttaaga
     5281 aaccttcata gacaagatac aaaaagaaat aagattagac catttcctat ttttaatact
     5341 aaagaaacaa atatgccgta tagataccaa tttttagcag aagactttga tactcaaaga
     5401 gatattaatg agattgatat tgcatgtgaa catatcaatc tatctttaca agataaccaa
     5461 attccatatg caaggtttat caaagattta aaaacacgtt tggagtattc aattattaat
     5521 aatattccta ttagtgaaga agactatcag gattatctaa atttatcagg atcacaacaa
     5581 acaattaatg aagaagagct gttaaaactg gtaaatacgg aagtaaaaag tcaagatatg
     5641 gaaggtcaag ttttatcaga acaagaaatg aaaattaata tttatctaaa ggaaagtcaa
     5701 aaggaagcaa tagaattagt aaaagtaatt aatggaaggt tagctgatga aaattcagca
     5761 gatatggtta taaaaaccat taattcacaa atccttgata cgcctttcat tcaatcttta
     5821 atcaatgatt ctatagctat tcataatgtt caagagagta aggatcaaat tatgatccta
     5881 gaacaacaat tagctaatgc ttatgagtta gcagtgttta aaacgaaaaa ttcaatactg
     5941 aaaaataaaa ttatcaagtt gaaaaatgct atgactaagc tagcaaaagc aatttagaga
     6001 gaagggaaga aatattgact gaatctatta attggagaaa actaaatgtg caatggttaa
     6061 agtataaatg gccaatcata gtttccctaa taatcattct atttatggcc tatccgcaac
     6121 gagtttttgc gttgccgtgg attacagaca ataaagaggt attaaaattt ttaacaaaat
     6181 atcaagatta tcttcagttt actaaaggtg gttttggaag cattgtcgtt caaagtttat
     6241 cgtgggggct gattagaggt gcatattttg tttgtaaatc agcagaaaac cttgttccac
     6301 aatcgctaag tttgtttagc tttgttgaaa gcagtagttt aggtgctgtt tatcaatctg
     6361 tattaaacac ggtggttgta ggattaatga tcctttcatt gatgtttgtt ggttacaaga
     6421 tgattactgg aaaaggaaca gtggatttaa aatcggttgg aatgaacgta gtgatgtcta
     6481 tagcattaat acttttaatg ccaaccatga tttctagtgg tattcaattt gctaaaacat
     6541 tttataagga ctctactacg attacaaaag ctgatggggg cgttgcttgg tcattgattg
     6601 aggacggtgt aactgattta gtatatatca ataaaaacga tgcttatgat cggttgggta
     6661 aagatggcgt acaaaaaaat gcgttaaaag aaaagaattt cttttcctac gatttcagtg
     6721 aagtaatcac agttgataca gctaaagatt tagaagatga taataaaaaa gctgaatatc
     6781 ttcaatctag gttgacacca gatggcgaag gaaatatgca agccgttaag attgatgatg
     6841 gttggatgtc gatgttctct gatagtttca aaggagggta ctacaggttt actaaaaata
     6901 cttttgcatt gactttagga ttactttcgt tagctgtagc ctatgttttt agtattttta
     6961 tcatagtcac cgctatttta gaactggcat ttaagcgtgt gttaggggtt cttgtttttg
     7021 caacagatat tgagacagga cagcgttcaa aagttgttct atcagatatt ctacagtgct
     7081 atttgactgt aggctttcaa ggatttggat tatccatgtt tgcaatgttt gtttcctatt
     7141 taggaacagg cggagggtct tccgttaatc cgtttattaa ggctgtagct tatgtatgtg
     7201 ccgtttttgt tttaatcaaa ggcagtggaa cagtcatgag atactttggt gttgatattg
     7261 gactcaaaga aggctatggg caacttgctt ctgcttttgg aatgggtgca atgctgttta
     7321 gaaaaggatc aaatggattt aatcgtgcca aaggaagcgg aaacggaaat ggatcagaca
     7381 gcggagaagg agaagatcga aaaccagaaa agaatttcgg tgaaactcta tcaaaaaaag
     7441 ctggcaaaac tggaagagct ttgggatatg cccatgaacg tggattatca ggtttagctt
     7501 cagatggagc tacaatggct agtgaaagag caacaaaacc atttaagagt atgcgtgata
     7561 tggctaatga tactaagaat aagttcaaag aaggtttaga tgatggtaca gtgtccgcta
     7621 ttaataaaaa tagcaaacct atgttagcta aaaataaaga agatgaaact ggaaaatacg
     7681 ctgattccat gccaacacgt ctttcgaata gaaaagatgg tgctaaggtt gaaaatgccg
     7741 atagaattat gtctagttct gaacgtatgc gtgaagcaat gaaaaataat gctgaatcga
     7801 ataataatcc tgtaagtgca attcagcaaa aagttcaaca agatattgaa gaacgtaaaa
     7861 atgctatgca cggtcaagct aagtctgctg aagaattaat taatcagaag cgacaagaag
     7921 ctaaatacac gcctgaagca atgaatcgtg aggaaatgtt aaggaaacgt gtagaagggc
     7981 gtacaggaac taatacggac gaaaaagaag cgttgaccaa agaaagaatc caagaagcta
     8041 aaaactcaaa taccggatta gaaaaattgg tcaaagaaaa tctacaaaat tctacaagta
     8101 gtcaaggtgg tcgatcagta gatgtccgag aaaatattca aggttcattg aatggtcatg
     8161 tcggacggaa tgttgatgta agagagaatt tacaaagttc ttcaaatggt caaggtacta
     8221 agacaattgg tgttcgagaa aatctgcaaa gtagcagtac aagtcaacca aaaacagtag
     8281 atgttcgaga aaatgtacaa aattctacaa gtagtcaagg gtttaaatca gtggatgttc
     8341 gagagaatgt gcaaggtagc agtgcaagtc aaccaaaaac agtagatgtc cgagaaaatg
     8401 tacaaagttc tacaagtagt caaggattca aaacagtaga tgttcgggag aacgttcaaa
     8461 aagatagtgg agaaatgaaa gaaaaaacac aaaaaatcaa tatcgttgaa gacagaaagt
     8521 cagcgaaaaa atttgattca aatcatgaaa cagtgattat tgatagtgaa atccgtgaaa
     8581 atgataaggg atcaaaacca agacgaagat tcacttatga agacaacgaa ttattcagag
     8641 atacacttaa tgatcctaat ccacttttcg ataatttaaa ttaaattaaa agccggcatg
     8701 agtgattatg ccggcttttt atgaggtgaa aatgatgtat agaaatccca aaaatataaa
     8761 acaagagata aagctatttt tcttctattt agtcgattta ggaatagtag ccggaagcgt
     8821 gatggcaagt gtttactttg caaaattaat gccaatttca ccaatgatga aatttgcact
     8881 gtacttatta gcatttgtag tgggtgtttg gatgtgcgtt agaacgccta atcaccctaa
     8941 agagcgaaat attttaatgc tgtattatct ctttaaaatg gatagaaaca gataccacga
     9001 agtagagttt aaaagaaata gtagggggaa aattgaatta tgattgttgc tgaaagtaat
     9061 gaaaataaat taagtggtgt ttttgacaaa ttcttagaac tagttattcc aaaagataaa
     9121 gatatgtgtg aacttttacc atataaaaaa atattgaaag acggaacgtt agtgactaat
     9181 gacaataagt atcaagcctt ttttaaagtt aaaacaactg acttaacttc tatttcagaa
     9241 gatggattta tgcgtatggt aaacaaactc acttatttaa atcgagtata tttagaacca
     9301 tataaaattt attcattaac ttatcctact gaaacagtaa atcaagcgat ttattggaag
     9361 catagaatac aggaggcaaa gagaagttta ttgagtaata atgatcccaa tttagaaacg
     9421 tatctgaagt ggaatctaaa gctagcttac gataattatg aaagagttga tctagtatcg
     9481 actttaccag agttgatgtt cgttatttgt gtttatggaa aaacacaaaa agaagtgaaa
     9541 aatcatgccg atgtaatgaa acaggccggt ggtagagaat tagatttaca aagaattact
     9601 gaaggggatt taatcaatgt gataactaaa ttgatgaatc ccaatacttc tttataaggc
     9661 ggtgcttatt atttgttaaa gcactgtaga aaaggatttt gtaaagtaat taaaggtaaa
     9721 aatgctgctg atttaatctt tgaatggaaa gaatctaatt taattaatgt acgtgggaaa
     9781 aatggaagcg gaaagacaga aagagtgatg gctagtattg ataattcaag gcctagatca
     9841 agagcattag taataactga tgaaaaaaat cactataaag gcatacgaac gatagaaaaa
     9901 aaatatttaa ctaacaatga tttaaaagta gtagatgata ttttaaatat ttatcctgat
     9961 tttaatttag ttgtttttga tgaaacaatt cctgtgacag aaataaaagg attctatcaa
    10021 agcttttcca atctagcaaa taaatatgag gaagttctgt ttgtttggat tacagaagaa
    10081 gatagtaata gcaagtcagc gttctttagt gaaaagaacg cttttttaca ttctatttaa
    10141 aaaggagaat tgaacatgat tgtaagtaaa aaactagcaa gaaatctagt aagtgaaggg
    10201 tatgacttaa gattagtaga aaagtatcaa ccgagcggtg gaattaaatt tgatgagcgt
    10261 tatatttcta ctggtgatgg atatgtaact tcgattgctg ttattgagtt tgcagaagat
    10321 gtaaatagtc gatggttaac ggatataatg gcaattccaa atactattgc aactttcgat
    10381 gtatgtacgg cggataaaga agacttatta cacaaaatca atacgtctat tggagaatta
    10441 gattaccgat caacaaatga gaatagaaca actgacaaaa cagacgcttt actagataaa
    10501 tacaatttag aagattttgc acaagaaatt acgaaacgtg gtgaagttgt caaaactgtt
    10561 catgctcgta tttttgttta tagcgattct ttagaagaat tagagaaaag aattagtgag
    10621 attcgtaaag atttggctag tgtcaatcac aaggcaattg ttccgcaatt tagaatgaag
    10681 gatgaatgga tgtctttatt tcaagatggc atggaacaag aatcaaaatt atttgccaag
    10741 aaaggcttaa ctgttccggc aaaaaatatt ggtggcggta ttccatttca ccacaagagt
    10801 ttgaaagatc cacgtgggtt ttatttagga actacgtcaa ctggtggtgc ttttatattt
    10861 gatccatttt attctacgaa gcaaagacgg tcgtttaacg gctttatttt aggaaagatg
    10921 ggttttggta agtcaacttt aattaaacag ctacaggaag gcctacaagc gaaaaattgt
    10981 tttattcgag gatttgacaa gtcaggtgaa tttgaaggca tggtgaagaa agcaggcggt
    11041 gtatacgtcg atttaggcgg tggtgatatg gtagtaaatc cattgcaaat ttatgcaaca
    11101 gtcatgaaaa aagatcaatt tggaaatgat gttgtagatg aatcaaagag ttttcaaaat
    11161 catatcacta agtgtagtaa tcaaattcgc tttttagaac ctgaaattga tacggcaact
    11221 gtacgtgaat atactttgat gttacaagac ttttatattc attatggaat tttgccaaaa
    11281 gaatggagag aagcgagaga cgacaacgaa cgaaatcaat taaatacaaa tatttgtaac
    11341 ttgcctaatg attcatatcc aatctatgga gagtttctta aatttattga aaatcaacaa
    11401 ttcaaaatta aaaatgctac tcctgaacgt gtccgttcta ttgagctaat taagcttatc
    11461 gttacggata tgtgtacaac ttatccgcaa attttcaacg gagtaacaac aatgccaaac
    11521 tttgatacaa caaaaattgt ttactataac attgattcta ttagtaaaat gagtgcccca
    11581 gtattccatt gccaattatt tacagcgtta acgactattt ggaacagtgc cttgcaaaac
    11641 ggaaagattc aaaaagaaaa ctttaaaaaa tatggcagtg attattataa gtatgcacaa
    11701 gatttcatgg ttttgatcga tgagtgtcac aatgttatca attcaaataa caagtatgct
    11761 tgtgaatatg tactaagttt tgagcgagaa atgcgaaaaa tgcgtgcagg tgtttatttt
    11821 gcaactcaaa cgcctgaaga aattatccct aaagattctg gatcagaagt agcagatgtg
    11881 attagaaaca tttttaatct atgtactttt aaatgcttct ttaatttaga ttctgcattg
    11941 ttggaagaca taaaaaaagt tttaggaaat acaattactg atacagaaat tatgctttta
    12001 ccagaattag aagtaggaca agctgtagtt caaacttcca gtgaagacac ctatatgatt
    12061 aattttgatc catatccaga gcaaattgaa cgattcgatg gtggtcaata atagaaatcg
    12121 gaggtgaatt taatggagca gaacaaaaat aataatgttg cttcaacact cgctcgtcaa
    12181 gggatgaagc aagtatcaaa gaaaataggt cttgctttaa aaataaaaat aggggtagtt
    12241 ataggactga taacattggt tggcctttta gttataggtt ctttagctac attacaagga
    12301 acacaaactg caactaatac aggaggtgca gaagtcattg gtggcaacaa accgttgtca
    12361 cctgaagttc aaaaatggca aaaaacggta gaaaaatatg ctgaaaaata cggaattaaa
    12421 gaattagtac cttatgcttt agcaattatg caatgtgaat ccggaggtaa attgccggat
    12481 ttaatgcaaa gtagcgaatc agccggattg cctgtaaaca cacttcaata tgaagaaagt
    12541 atcgatcaag ggctaaaaca tttgagtaat gtgtataaca ttgctaaaag ttatggcatg
    12601 gaaagtaact atgatggaat agttcaagct tacaattacg gaatagctta catgcactac
    12661 ttaggaaaaa acaaaaaaac acatactatc gaaacggctg aagcctactc taaaaatgtt
    12721 gttgctccaa gtttaggaaa tactacagga cagacttatt catatgtaaa tgaagtatca
    12781 attaaatatg gaaaaacata tttgtattta aatggtggta atttttacta tgcagagtta
    12841 gttaaacagt atatcggtgg gggtagtggt aatccggcta atccttcaga attttgggga
    12901 aaaatgaaaa cagaaatgga aaaatatcaa ggttggcctt atgtttgggg cggtaaaaat
    12961 ccaacgacag gttttgattg tagcggatta acagcttatc tttatcaatt tagcgccgga
    13021 attacaatag atagttatac agtaacgcag tatgaagcaa ctgaagcagt atcaattaaa
    13081 gaagcaaaag ctggtgatct gattttcttt agaggaacat atggagcgcc tgatttcatt
    13141 tctcacgtag gtatttatgt caatgaaaca actatgtatg acagtaattc aagcggaatt
    13201 ggttatcaca attggcaaga ttcatattgg caatcacata gtccagagat tcgtagagtc
    13261 aaaaaatagg aggaagaaaa tagatgatta agagaaaaaa tgataataaa tggaaatata
    13321 tttgtggtgt tttaattatt attttagttt taggtggatt gttatctcaa cttcatacaa
    13381 gtaacattca agcaaaaaat aaaaaattgg atcaagaagt tacacaacta gaagaacaaa
    13441 atagcaagtt aagtaaaaat attagtgatc taaatgcaaa tgtagaagcg aacttaacta
    13501 atgatgatgg cagtgaatta aataaacaaa ttgctgaagt tgctaagaaa tttgttgagc
    13561 tatatccggt atatgatatt gaaaaagtag aagaaaagaa agctgattta gagaaaatag
    13621 ctactccttc tgtagctgat tctatcgtgc cggacgacat gattacaacg agtaaaaaga
    13681 ctttagaaag taaatctact actcaaaaag gagaagcata ttcaagtgat ccaacattca
    13741 aaagtaaata taaagattca aaattatata cgaattatgt taacgccaat actattaatt
    13801 attttgctga agtaaattat aaaacagaat cttctagtgg agatacagaa aatacagtct
    13861 atatgctttt tgaagtaacc aataaagacg gccaagtgtt ggtagataat tatgaaatca
    13921 agtacttaaa atagtgaggt gaagtatatg aataagaaat attccattca taataagaag
    13981 gaaccaaata aaaaaaataa ggcacaaatt gacaaagtat ataaaaaaac gaaaggagta
    14041 aaattatatt taggtgctat acttggattt ttagcaatag gaatgataat cgttttttct
    14101 ccttatgtga tggggaaaag ttatgatttt gaaactgtaa aaatgagttc agcccaaaat
    14161 gtaacgtctt ctttgaatat gtatgttgat gatatggaaa taaataggga agccggactg
    14221 tttaaattag tattgcggta tcaagatgat acaggtacta aatcactaag taatattaaa
    14281 agtgactata aattaaattt tataacgaac aaaaataatg aagatgttaa gacaaaagtt
    14341 gtaaaattgt cagatgaata cacggtaatt tattatcaaa atctgcctaa agattttggt
    14401 gtaatttctg tgacagttaa ccctagatat atttatcctg aattagaacc ttcaaatgac
    14461 ttaaaagaaa aggaaataaa attctatgca gtagacaaag atattaaatc aaatgctaaa
    14521 ttggaagttg aaagtacttc tgatttgcaa aaagataatt ttaaatatca gattaaagct
    14581 atagaaaatt ctataaaaga tgagaaaaaa tcaattgaaa aaatgaattt agcaaataaa
    14641 gtagtgcaaa aagatattga taaagctaat caaaacttag aatttcaaac cctagacgaa
    14701 caaacagata caaaaaatga aatcagttct atgcagacga ctattgaaaa taataaatct
    14761 tcaatagagg aaagtgaaaa taaaatcaaa caatttgagg aaaaaataaa gcaactagaa
    14821 aagtctgcaa gccgatttga gtgatcgtgt ttaaattatt ttaagggagt ttagagagaa
    14881 tgtgtaattc tattgtcact attcaagaga aagctgaaga agaattaatg agaattgaag
    14941 cggaatataa agaaaagaga aaagcgatta agcgcaaaaa aaatgcagag cttaaaaaat
    15001 ataaagagga acaagcgtta aaattaggaa tgatgttgtg taaatattat gattgctatg
    15061 atataaacga agtgctaaaa aaagcgaatt taaaccaatt ttgtgaatag aaaagagagt
    15121 ggcaaggtaa aacttgccac tctttttttg ggcgtaaaag ctttagttac tatgaccaaa
    15181 actacggacg aaactatgac caaaagtagg tactatatta tgaccgaaaa taggtcgaaa
    15241 atggattttt ttgtgatagc aaaaaatatg aagctatttt gaaagaaaac cagttggcac
    15301 agccaactta gccaccttcc tttaggaagg tgctatcagt tttcccttat gctctttgta
    15361 ttaattcctt ggtcttgtct ttaaatcttt aattttcctt tggactttga tataataata
    15421 tataccagat agataaaaac agcttgaaag aggtgtgtgt atggatgttt caatcagagg
    15481 aattgatcca caatatgtaa aagagattga taaaaaagtt aataaaattc aagaacgtac
    15541 cggaaaaaag tttagtagga atgactattt tttagcaatc attcgccaag atagcgagat
    15601 cgatttgatt gactataaaa agtcagaatt tgatttagta gttgaaaaac ttttattgtc
    15661 aaatgaacaa atggtagaaa gtattagcga gttaacttca gtttatgaac gcttattcaa
    15721 ttttttaatt agcgaaagga gtgatttaaa taaatgaact acccttattt caaagtatca
    15781 gcaacagaag atgtaaaaga aaaattcaat aagtgctttg aagtaaacaa gtcagtattt
    15841 caaacaaaat ccaatatgtt ccgttatgtt gtttcaaatt taccaatgtt aacaaaagcc
    15901 aatcaaaatt tccgtgatcc agaaaaagaa gagttagcta aaaacttaga agaagcaaaa
    15961 ttaaaaatta gcgaacttga aacgataata gaattgcaaa aacagcaact tgaaaacttt
    16021 aataaaaaag aagacagtac acataaagat tatagtgaac aattaaatag tatagaagag
    16081 tctgtctata aactattaat taatagtgga ttagctagta aagaattaga agaagagcgt
    16141 gctgaaccag aacaagaaag tagtcgtttg ggagagggaa caatgtttag ttcaccgtca
    16201 ttaagattta caacggattg aacactaaaa aattctaatg caacttagca ttaagtacaa
    16261 aaccgcctgt agaaaaaatt tttgaaaatg gtgggtgatg atatgactga acatatcttt
    16321 aacagaaaaa gtgcgagcat tattcttaaa gcaaaatttg aaactggaaa aagcaaaaag
    16381 aataatcaca tggtagaact tcaaaaattt gtagattata tttccagaca agaggctatt
    16441 aggcaagata aactagatca tgattattca gaagatgaac taaatgaatt agctagaata
    16501 gaaaaagctt tggaaaaaat agaacaggaa acagatcaac cagtgattaa agatttacgt
    16561 gaaatggata aatatattga ttatatgaca cgtaaaaaag ctatcttaga aaatgtagat
    16621 aatgaaatag taaacggagc atttagcaat acaaaaagat atatcactaa aaaagacatt
    16681 tcaaaaataa aagaatcggt catagaagca aaaaataatg gatcggtgat gttccaagat
    16741 gtaatttcat tcgataatga ttttttagta agggaaggat attataatcc agaaacaaat
    16801 gaattaaatg aaaatgttct atatgaagca acaaagtcta tgatgggaaa aatgcaagaa
    16861 aaggaagaac tagttgatcc tttttggttt gcaacgattc acagaaatac tgaacatatc
    16921 catattcatg taacagctat ggagcgtaaa aatactcgtg aaataatgga atatgatggt
    16981 gttttacaag ctaggggtaa gagaaaacag tctacgttag acgatatgat ttttaaattc
    17041 ggtagcaaaa tattagatag aacgaacgag tttgaaaaaa tttctaagtt gagaaaagaa
    17101 gttcctttag aacttaaaca gtctgtaaaa gattctttga ttcaattata tgtagaaaat
    17161 aattcaagat atgacaaaga attagtaaag tacctaaagg aattaaaaaa agaaatacct
    17221 agtacaacac gtggctacaa tgagcttcct gaagaaacaa aagaaaagat tgatgaagtc
    17281 acaaattata tgacaaagga taatccaaaa agaaaagaat atgatcgtat gactaaagaa
    17341 attgatgagc tatatcaaac aacctacggt aaacgctaca atccacaaga atattattta
    17401 aatagaaaaa aagattttaa tgctcgaatg ggtaatgctg tagtaggaca aatcaaactt
    17461 ttaaagcaat ctgaagaaaa aaatttgaaa agtaatgaac ttaaaaatct attagacgga
    17521 aaaaaattaa acgttaagtt tgatagagaa aaaccagaat ttaaaacgaa atatgctaaa
    17581 caaagttatg atgatttcca aaaaagatta gaagaacgac aattagcacg tgaaaaaaat
    17641 gaagtccact tcaagaagat ttctgaaaaa tttaaagata aaaagcttat tagaaaaatt
    17701 gatagagtaa tcaatgatga tttaaatatg tatcgtgcga aaaatgatta tgaagtagcg
    17761 caacgaatga tagagcaaga gaaaatgaga caagcacgtg aatttgaaat aggaatgaat
    17821 tagtagaaac ggagaataga aattatgaaa aacttcgata tagtgtgcag taatacaaaa
    17881 aatatatatt tacgtgagct acttaacagt gattcggaaa ctatagaaga tgtaaaaaaa
    17941 atcatagtgt tgtttgaaaa agaaaacatg gagctagaga attgggggct ttttgaaata
    18001 ccgattagtg ggaattactg tttttataat tggaagacag aagacgatgt agcttttgca
    18061 aattactttt ttgataaaaa ttacttttcc ccattatata tagataagca tagtaatgaa
    18121 caagttgctt cttcaataaa agaagcaata aaattggaaa gagtgaggaa atgatatgat
    18181 cgattttaga acggttatgg ataaactaag taatggagat tttcgcgtat tgattgaact
    18241 atacttaaat gtaacgtcta cagtcaaaga gtttttatat tctaatccca aaacagcttt
    18301 agtattagtt gcagtactga tagtttttgc tgtgatctct tttattaaga aaatgattcc
    18361 gctattaatt ataggtgctg tgttgatatt aggtttgtat ttccctgaag ttttggatca
    18421 aataaaaaat atattttagg ctctaaaagc ttccagtaga aaattttggg ctttgatatt
    18481 tgtattaagc ggtttgaaat agaaatttga taaactacat gaaaagacat tatataagag
    18541 tatctgtgta ttggaataaa aatatgataa tataaaatta tatatcagac cgataaaaaa
    18601 gaggtgctta taaatgaaaa agttaagagt tattgcaaca atacctatga tttttagttt
    18661 tgcgctatta ttatctgcat gtggcaaaga agaagctggt gctaagtcaa atgaagcaca
    18721 taatatctca ttcatagata gtgcagaaca aaaagactca cgttgttggt tggtagtcga
    18781 aacaagtagt aaaaataaaa cgcctattga taaaaatgaa tatgtaaaag cggtgatcca
    18841 aactaaagat ggcaaagcaa aagtatttaa aacggatatg gaacagctta cattggaaaa
    18901 agtttctaaa atgagtgatg aagaaataat agaacaagca ttgaacgctg ataaacaaaa
    18961 gtttaatgat aagaaaaaaa gcgatattga tagctataat gccactttag attctgtaaa
    19021 aacagaatta gaaaatgagg aaaaacaaga gtttcaaaat gaccaaaaaa ttgctgattt
    19081 tcaagatagt atacctaaaa tacaggcgga tatagaagag atcgatggtg ttcaatattc
    19141 agagccggag tggaaaatgg tatcagcaac aattaaaatg gataatgaaa acaaatcacc
    19201 ttcaatggaa accgttaaat tatcttataa atatttagat agtccaattt ggaatttaaa
    19261 tagttttggt gaagtttcgt ctgaaggaga attatcttat gaatctacta gtatggattt
    19321 gaagttatca attccagttg ccacaacgaa agttttagat aatttttatt caggatattc
    19381 taatgatgaa ttggatcaac ttttgcttac taaagtagct tctaaagata acaaagttca
    19441 attagatagt aaaggtaaaa acgtaagtat agttgagtag atggtaaaat aagaagggat
    19501 aagatggtta ctataactat cttatctctt ttttatttgc attaagtcag tgaaattaga
    19561 tagaagagtt tttatatatc tggtataatt taattaggta atttaactta cctaaaaaag
    19621 aaaggagata gaagatggcc tataaaaaag gaaactggaa gccgaaaacg aaagagcaaa
    19681 aacaaaaaga gctagacgat ttaattaagg cttccaacag caaaatcgag caatatcagt
    19741 ctaaccctga agatatgatc gagtttgcca agttcatgtc taaaatacac aattacagtc
    19801 ctttaaacct atcgttgatc gatgagggat ttgaaggagc aattgctgta gcaagttatg
    19861 atggttggaa aaaactagga tttcaagtta aagcgaaaga aaaagggata ggcatttatg
    19921 cgcatgctcc ggtaacggtt tttattgatg aaaatggtga ggaaaagacg ttaaaagaag
    19981 cgacaaacga gcaaaaagaa aaaatcaaaa atggagaatt aagaagcaaa aagatcaagc
    20041 attttaagaa gggttacgta tttgatattt cccaaactaa tgcaactgaa gctgatttgc
    20101 caaaaatatt tcctaacagg gtatggaatt ttaatattga tggtgaatta agtgttagtc
    20161 aattagaaaa aggtgtaaat catttggccg aatctatgaa tatatctata aaagatatga
    20221 acgagtctgg tagaggtgaa atgggaagcg ctagaggtga atatattcaa tatgttgatg
    20281 gtagggaaga aattgtatta aattcaagaa atagcagaac acaaaatctt actaccagta
    20341 ttcacgaatt ggctcacaaa aagcttcaca ataagaatga acacggttct tcctactcaa
    20401 caccgattaa agagtttcaa gcggaaatga cttcatttat tgtttgtcac aattacggta
    20461 ttgatacgtc agactttact attccttata ttgcaaattg gactaaaaat aatgaaaaaa
    20521 ttgatccaaa aaactttaga cagataatgc aagaagttag agaaacgtct attgacttta
    20581 taagtacgat tgataagaaa gtcttggaag aacagcaaac agcatttaat gcactaaaaa
    20641 attcctttgt tcctaatgag aataaagagc agatacaaca aaaatcagat ttagaatttc
    20701 ataatttcta cgatagtaca atcaacgatc cggatagaac aatccacggt agttatttag
    20761 aagcgatggt ggattattat agaggaaagt atggagaaaa ttctattgag cttactcata
    20821 gcaattatga tgttacagct aaaataggag aaaactatgt gacatattat tcagatacga
    20881 aacaatttga tgtatgtgat gtttatggtg tagtttttga gaatccaagt gaaaataaac
    20941 atgatcgttt actattagat cgatcacctg aaaattgtga ttatgttgaa aagtttgttg
    21001 tagaaagttt gaaagcttgc gagaatcatg aactaaaaaa tgatacgtta aaattaagcg
    21061 aaccgctaag atcagttgtt ataaatgaag cggtttataa tctatctgaa aatgctaaca
    21121 attactataa tgaaaaatgc tggcaagaag aaattgaaaa ccaaacaaat attaatgatg
    21181 taaaagaatt aaactcttgt atgactgcgg aagattttta cgaatctcat aaacaagaaa
    21241 tcgaaaatac gattacagat tttgaatctg tgtcaggaac aaatttaaga gatacaatag
    21301 acaatgagtc atataaagag gtggcttcag tggtagctta taaactggtt gcaactaaag
    21361 taaaatatga aatggatgaa ggaactttca agataccaga aaattctaac ttggaaaagc
    21421 cgactgtaaa aacagcagaa cgttcttttg aaatggagtg aaaaaattat gagtaatgaa
    21481 caaaattatg aaacaggcgg aacttatcgc ctgtttcatg gaagtatgaa taaatttgat
    21541 gaatttagtt tagatcataa aggtttaaac ggaacagcta atggatttgg tgtgtactta
    21601 acacctaata aagaaatggc tacaatgtac gctgaacagg gtagtaacgg aaataatggt
    21661 ttcgtatatg aagtaaatgt tgaattagag aagccgattt ctatgaatga acgcactatt
    21721 actgatgaag agctttctaa agtaatagat aaattacaag aaagtaatga tattttaaat
    21781 gattacaatg atgttagtta ttacggagaa aaagttgtaa aaagagaagt gattgcttct
    21841 cttagtgaga atgaaaatga cgtagatttg attaacgaca ttggaaatac aattggagat
    21901 catgaagcta ctgctaaggc attttatgac gttgggaaat atacacatat tattgcggaa
    21961 gaacagttaa gacaaaagga tgtagttatc gtagtgttac agcctgataa agtaaagatt
    22021 gaaactattc acgatttaaa cgaggaacgg aatagcttag aaagtagtga ggacatgaca
    22081 gataaatttg ttgggcataa ggtttcggaa gttcccattc gagaagttgt gataaaagat
    22141 tttgagcaag agctagaaac aactaattat tatgacaaac aagcttggca agagcgcatt
    22201 gaatacttag aaaacatgga agaaccagtt tccagattag cattagatag tgatattaat
    22261 gaattttatg atagtcataa agaagaaatt gaaacgaaat tgacaaattt atccgaaaag
    22321 ttagagatcg ataaagaaga actgctaggt tttccagtag atacttcttc tacggaatac
    22381 aaaaaagcta cgtctatcat ggcttacaac ggtgcaatga gagaaattta taatgaaatt
    22441 gaaaatgata cgtttgaaat accacctgtt tctgaagaaa tggagaataa gattttgaaa
    22501 ttgactaatt ttgaaaatac aacaaaattt gaaatggagt agataaatga atgatagaac
    22561 aagaaaatag aaatttttta gaaacgcaag gtgaatatcg tcaaattaat aatagtcatt
    22621 ttgtaatttg tgaagatgta caaatcgctt ttaaaatggc tttgaagtac ggaaaaagta
    22681 ttagaaaaaa gataattaga gaaaaaaaga gcaagaagat aggcttttgg gagttatctc
    22741 ttagggatgg gctaaacttt attttctgta cagaggatta ttatgaaaaa tacaagtgta
    22801 ccttatcgta attttactag tgatggtcta gtaaaggggg tttttgtttg gatttgaaaa
    22861 aggcaaaaag gttctgttgc aaagtcttat ttagtaaatg agagaagaat cgatacagct
    22921 ttagtggaag attttttatc taaaggacta attaaacaag ataaaaaagg aaatgttttg
    22981 ttcttatgga aaaaagatca agaaatcgtt gggtgtacgg aacaaggaac tagaaaattt
    23041 tttcatgaag gcaaacaaaa ggatgttaca tggaaaaaaa tacaagaaaa ctctaaagag
    23101 tattcaggat ttaacgtaac ttttggtcaa ccagataaaa tgtatttttt tgaaagtgaa
    23161 atagatttga tgtcgtacat tacacaaaag ccagaaaaag ccgaaaatgc tacgtttgtt
    23221 agcatgaatg gattaaaggt aggtaatgta ttgcatgggg ttacagagca ttataataag
    23281 tttaaatcat tgccttcaga aacagtcctt tgtgttgata atgataaagc cggacgtact
    23341 tttattgaaa ctgaatttaa agaaaaagga attggaagag aagggatagg aatcagtgaa
    23401 gtaaaagtcg atgtaccttt gcgagaggga tttgattgga atgataattt aacaagagga
    23461 aaagaagctt ttaaacgctt caagttagaa gatgtatcaa aaatcgtgaa cttcacacat
    23521 aaattatctc ttaatactcc tgtatatgaa atggaataaa aagaagaaag tagttgatgt
    23581 gttatgaacg atacaatagc aatcttatca gattcattaa ttgatttaga taagacgtct
    23641 acagactata tgattattga agaacaactt aaaaataaaa atccagagtt cgatattcaa
    23701 gaaaaatcat tgcgtattga attaccaaaa tttaaacaaa aaaaattaat aactattctc
    23761 tttgagatta ttgaacgata tgggcttact tattatcaaa tttggacgga taagaaagat
    23821 ggccaatata caaaaggggt aagcatagaa gccgttagag aagacgatca agtaagtatt
    23881 aaagcagttc aacccttaat ggggtataac gaagaattat tgaattgttt aaacgtctag
    23941 tgtaaactag gcgttttttt acattatttg gctacgaata gacagttaat taaactaaag
    24001 aaaaccattg actacaagta gtcattcctg tatgatatag ccatagacta caagtagtca
    24061 aagactcaaa cccttgattt aataaaaagg agagataata gatggagcag acaagaatgt
    24121 tttggtcaga tcgaatgcaa gatcacttgg attgtattta caaaaccaga gagcaattaa
    24181 ataagttaga tactgtcaga tattatttta cctacttcag tgagaatgac gaacaaagat
    24241 gggatatttt tcatgatggt aattacgaag aattttttta cactgaaagt taattatttg
    24301 ttgaaatgat gaaggattct atttgatgaa agggaacgga aaaccgttcc cctaaaaaat
    24361 atccaaatga ctacaagtag tcatggaagg agagcggaat aatggtaaat aaaaaagaaa
    24421 cgtttaaagt aggtatggaa gtacagggcg ttgttattgg gagcggagag cttatcgagg
    24481 gagaagtaat tagtttgtta gctaatgtag cggtagttaa agcaatcgga aaagcaccgg
    24541 tagtgatgaa aaaatgcagc atgatgtgtc ttgatggttt aaacaatcca ataactcaac
    24601 gctttgagaa cgtgatataa tagaaaaaag aagattttct actgggagag attattatga
    24661 aagactatgc ttcacgtaaa tttatccact tagagcctat gaaagaattg gttattaatg
    24721 ggaatgaata taatgattac aaatctttat ttgtaaagga acagcctaaa ggcggtattc
    24781 ggatgaaaaa tttaccggac ttccgattta tcgaagtaaa caatttagga attatagaag
    24841 actatttaga taagttagat gaagcgataa agcaatcaat tgaaaaaaat ggtgaagatc
    24901 atatacttac ggttgtttta aaagacttga aagatagact agaagctgaa gcagagtact
    24961 ttaataaaga ctaataagaa gggaatgaga gctatgacag aggctgtaaa agaattaaag
    25021 aaaatgtatc ctgatgtttt gaatatgact gtagatgatt ttcatgaagc cttaaaaaat
    25081 gcagaaagtg aggaagaaag gactttctac cttacacttt ctagttttgt gacacgagta
    25141 gatcaaaaaa aagtaattaa tcagaaagac tttaaaatat gagtttagaa aatgaaaaac
    25201 cgtattatgt agttgttggg ggcgttaacg gcgccggtaa gtctactatt tatcaagttc
    25261 aaaatttaaa aagaaaagaa cttgatactg atagaattaa tgcagatgaa attttgagaa
    25321 gttttggcgg aaattggaaa aaacaagcag acataaacaa aagtatgcgt gaagttctaa
    25381 gagagatcaa aggtcatttt aaagaaggaa aatcttttca ccatgaaacg acttttggtg
    25441 gtaatccata tcccgataaa atgagacttc taaaggctaa aaaattaggt tatgaatcgt
    25501 ttttaatcta tataggacta gattcaccag aaagagcgat tgaaagggtt aaaatccgtg
    25561 ttgctaaagg tggccacggt gtacctgaag atttaataag aaaaagatac gaattttctt
    25621 taagaaactt agcagagtta gagaaatatt ttgataatgt aagtatctat gataattcag
    25681 atgagttttc ttatatttat gttaaagaaa atcatacagt tgtagccaat aatacgcaag
    25741 aatatgcttg ggttcccaaa gctattcaag agaaaaatgc tgaaactcct ataagcaaac
    25801 aaattatgat ggatatatct caagaagaga tgaatccaaa agaaaccctt gaaagaatat
    25861 attcagcaag tgatgatttt attagtgatc ggttttcaaa agaagcgcaa gtcgatgatt
    25921 tttataggaa ccataaaaat gaaatcaagg aacggattct atcaattagt ttttctacag
    25981 gggtatctca agatgaatta gtaggtcaag ataaaagaag aaattcttgt aaattggcat
    26041 atattaatag tgtaggtgag cttttagtaa aaactgatag tgagctatta agtatggaat
    26101 taaatagaga tagaaatatc caaaaaactg attttgaagt tgaataaaag aagttgtagc
    26161 tgaatcaatt aatagtaaat aaatttaata aggagtgcga aagcacttct tattttttgg
    26221 ataaagtgac tatatgtagt cagaaggaat aatatattat ttttagtttt tgtttttaat
    26281 ataattacta caagtagaca attgatcatt gattatagtc taggaaatat gttactatta
    26341 ttatatacca gatatataat aatgaggtgc taaaattgac aataataact atgactaaaa
    26401 aaatagaagt atatgttgat ggatcacaag aggaaagaga ttcgtttttt ggtttttttt
    26461 ggaaaaatag tagagaatat gtaaaagcgc tgaatatggt atataaacag ctgatgtttg
    26521 aagaattgat cgaaaattct ataaaagaat tggatcatga gtatattaaa agagagctaa
    26581 gtcttgaaga gcgaattgat aatttactaa gtaatgaagt gatcgatcaa aagaaattag
    26641 ataaaacgaa aagggaatta tctaaactac gaattgcgaa aaacaaagaa gccagagacg
    26701 ttttgacaca agctataggt ttaaaaagtc aaaccagaat acgtgatata gcaaaaaaat
    26761 tggactttga ttattcggat tttatagatt cagctaaaat gaaagctagt aaggatttta
    26821 gcaatgattt tgttggaatt gttactgggc aaagaacacc tagaatctat agaaataaaa
    26881 ataaatatgg attgttaccg ttcagaggtc gggatattaa gattcacaaa gctgacaagt
    26941 tttatatctc tttacctaaa ggatttaggt ttaaagtaaa tttaggtaga aaaccaagaa
    27001 aagccagaga tagcgcttta actttagaac gcattatgga cggtcaatac aagttaaacc
    27061 agagtaatct aatctttgag gggaaaaatt tatttttgaa tttaacaatt tcttttgaaa
    27121 aagattatca taagctagat ttcaaagaag gagctgaatt aaccataaag tttactgatt
    27181 tgtgtagcgg taaatgttta gttaacaatc aatctgtgat tgattttggt gacagcaaat
    27241 atataagtaa cttcaaaaat aaaattaaag caatgaaatc aagggagcaa agccgaggag
    27301 ttttttctaa aggcggtcat ggtcgaaaaa gaaaattaga tcaagataga tgggaagcca
    27361 taaagaaaag agaaagcaat tttgttaaaa cctataataa tcaatgttcg gcaaaaatta
    27421 ttcaaacagc tatccgcaat aagacgcaaa taatctgtat ttctgaacca gataaaaatt
    27481 atggggaatg ggcttattat cagttgaaag aacaaataat aaataaaggg aaaagatatg
    27541 gaatagaagt taaaagtgag tagaataaga aatcgttgat ttggcaacga aatagtgagg
    27601 ggacactcac tcactgaagg gttagctctg tcaagttgtg taaccagacg gaaggacgaa
    27661 tattgttgag gttttagaac catgtaaaac aacacagttc tcaaatgtta cggataaacc
    27721 gtttgcggga aatcaggttt taaaaccatg taaaacaaca cagttctcaa ataaggcttt
    27781 attgaattga tcagtagttt ctgttttaga gttatataaa acgacatggc tcttaaatag
    27841 gagctaacga agaaaaagaa ggtactccgt tttggagtta agtagaaata aaaaaataga
    27901 atcgttgatt tggcaacgag ttgaaaaata cgcaaaacta tggtcaccaa gggataaccc
    27961 tgaaactgat gatcgctata tcttactagt agttaaacag tctaaatagt actcatttat
    28021 tgtattgatt ctaagggaac ctgcaataaa tgagtactat tttactttta attccgctat
    28081 ctatgtcatt aggcaactaa attgttatta atatatttac gtttactcgt atatttttag
    28141 taacgcatct gtcaaaactt tagaaaaatt tattttatct ttttcccctc tagctactaa
    28201 ccattctggg actgtgacgt ttttgcgtac ggtctttttt tggataaatg gagaaggatc
    28261 actttgaata agagaaacaa ttttgttatt gcccaaatta tttagttgat gaatatctgt
    28321 tggagaagga actgaaatat cttcatcaat atagtaagct agaatcccat caagaaattc
    28381 tttagcattg gacatagctt cttcaaaatt atctccttgt gttgctccag caaaatcagg
    28441 aaaaactact gagtagccat tttcttcagc agaaaaaatt acagggtaac tttttttcat
    28501 ttccaccact cctttcgagt taatccaatg aactaaagga ctgggctatt tcagccctaa
    28561 gtcctttagt aacttctgct ctgtcccttt ttttaaatcc tgattactat gaacaggaat
    28621 aggaacgggt gggaatcctt ctttggctac aatatgatgg ctgccagtta tcctcaccac
    28681 tttccaacca tttttcttgg ctagtttgag cattttttta ccggtaagtg gcattcgcga
    28741 ctacctcctt acaaatatta ttatacgcat tatgcgtata aaggtcaaga gtttttacat
    28801 taaaagtaga atgtaagtgt cacaataggg tataccctat tgtatcatat ggtaaagtac
    28861 agtataataa ggtttggagg tgtaacacta gggtgtaaca caatgtgaaa tttggaggtc
    28921 attttttgaa caagaaacag gatcaagaat attatataga aaaattggag aaagagaact
    28981 tagaactcaa agagcgaata agatactatg aaaccaaatt ctgtaaaaga ggtgattgta
    29041 tgaaaccaaa tcctgttgaa acaggtaaaa gaattaaatc aattcgttct aattttggaa
    29101 tgactatgga acaatttgca gatttaattg gaaatgctca aaaaggaaat attaataatt
    29161 gggaacgagg attctccctt cccaacaaag aaagattaat taaaattgct gaattaagta
    29221 acaaaactat cgactggatt aaatggggaa ctttagaaga atatataact tcatacctta
    29281 tcggtatagg atatgagcta tatattaaag actttccaga gatacctcac aaagtcttta
    29341 aagacattca agaaaaatat agtgatacgt tttcgttaga taaagactat gaattattgg
    29401 attctataat aaaaaatata tttacaaaat attactcaaa cggttgaatt gatagatgga
    29461 ctcaaagaag aaaattcaaa gttaaaagag aagataaaat actatgaatg tttatttgat
    29521 ggtatagaga gtctgctgaa ctcacgaaaa aatccctagt ttttatgaat gaccgttttg
    29581 taaatctgat tgaaatagat ttatatgatt tcggtatatg atatacatta ggaggtgtcg
    29641 aatggaaata aatctttttg aggctggtaa tcgaataaag caaatacgag aaaaacatgg
    29701 atatactatg gcagacttag gtaaactggt tgatgccaat agtcctagca caattaacaa
    29761 ttgggaaaag ggaaataact tacctaatag aaagcgtctt gaaaaaattg cactattagg
    29821 tggtacttct gttgaatgga taaagtatgg agatttttcc gattatgttt atcgcttgac
    29881 acaaaatata gaggaaaaaa ttcttaaaga gtacggagag actacactga acaactaccg
    29941 tgaagctctt ctagatgaac ttacgattga aaaaatcaca tacgaagaag atacaaagat
    30001 attagcagct gccgaaaaaa tcaatacaca aaatattttt caggaggtga agtacatgta
    30061 ttctcctgat gaagattatc gaaatataga agtcaaacca gatttaggac tgactgatga
    30121 caacaaaaat attaaaatga ttggacaacg tataaggaaa ataagaaaaa aagagaatat
    30181 tacattagaa gaattcggca aactattctc tcctacagct gataaagctg ttataagcaa
    30241 ctgggaaaat ggtaaaaacc ttcctaactc agaaagaatt aaaaagattg cagaaattgg
    30301 cggagtttct gaactttatc ttatgacggg tgtcgattca agcgtagcag aatcaatgta
    30361 ttttctatct gaagtagcat tggatgcttt ggaacgtctg tcaattgagg aagtcaatag
    30421 aataattgaa agcttcgccg gttatcttaa tgtgatttca aaaattgatg atccagataa
    30481 gcgagaaata tctctcaatg ctatttgtca actatcactt ctcgataaaa tgggttgatt
    30541 cacaaaaaat attgaaagat tactttactc acgaggaggc ttagctatga aacctaatct
    30601 atcgttaact agtgaacgta ttagaaaaat tatcgaatcc aaaggtctga cattagaacg
    30661 attcggtgat ttaattggcg acacaccaat aagttctgtt aataattggc ttagaggcgt
    30721 gtctttaccc aataaaaata ggcttttaac aattgcaaat attggaaaca ctagtgtaga
    30781 ctggattaaa tggggaactt tggaagaata catagcttca taccttatag attcaggtta
    30841 tgagctatat attaaagact ttccagagat accttacaaa gtctttaaag acattcaaga
    30901 aaaatatagt gatacgtttt cactagataa agactatgag ttattgaatc ctataataaa
    30961 atttactata gggggcgtta ctttgaatag aataaaattt tatattgatt ccagtaaaaa
    31021 gaccattaaa caaattagta cagaaactgg tattaactat acaactctta cgaactatta
    31081 ccgtggtgag cgaaatccta gaaatactga aacatggaat atccttgctg attatttcca
    31141 tgttcctgta agttatttga tgggattaga cgaaacaaat gttgaactca aaaaccttaa
    31201 tattggaaac aacatcaaaa atattagaaa aagtaaaaat atgacacaaa ctgattttgc
    31261 tgagttaatg ggtctatcac gatcatatat aggggattta gaaaacaaca ggagtaatcc
    31321 cagtataaaa acactggaag ctattgcaag agcattggac gttccgatag tagcattaat
    31381 caacgattct tctactgata atatagtaga gccgtatgaa agtttgacag ccgaaaatat
    31441 ccttcttaaa caagaaaatg aggaattaaa atatgaggta gaaagcttac gaaaaagatt
    31501 gtatgaaatc caacaagtag taaatcaagg agctgaaaaa atgattccca atctaaaaga
    31561 cgtaagtaaa agaatcaaat atatcagaaa aaaattaggt atgactatgg agcaatttgg
    31621 ttctcattta agcaactcac ctaaaagtac aattgctact tgggaaagtg gtagaaatat
    31681 accttctcag aaaaagttac agctgattgc tatagtagga gaaaccacca ctgactggat
    31741 taaatgggga actttagaag agtatataac ttcatacctt atcggtatag gatatgagct
    31801 atatattaaa gactttccag agatacctca caaagtcttt aaagacattc aagaaaaata
    31861 tagtgatacg ttttcgttag ataaagacta tgaattattg gattctataa taaaaaatat
    31921 atttacaaaa tattactcaa aagaatttga agtaacccaa attccataag agaggtgatt
    31981 gtatgaagcc aaatccttca gaagcaggaa aacgaatcaa acaattacgc ctttcatgtg
    32041 gttttactat ggaagaactt ggaaggaaaa tagataattc accacgtgcg accatatcca
    32101 actgggaacg tgggaccaat ttaccaaatc cacaaaagct gaaattatta tcaactatca
    32161 ctaattcaac aattgactgg attaaatggg gaactttaga agaatatata acttcatacc
    32221 ttatcgatat agggtatgag ctatatatta aggactttcc agaaatacct cacaaagtct
    32281 ttaaagacat tcaagaaaga tatagtaata cgttttcgct aaataaagac tatgagttat
    32341 tgaatcctat aataaaaaat atatttacaa aatattactc aaaagatttt gaagattatc
    32401 gagacataga agttaaacca gaccctaaaa aggtagggag aaaaattcgt tctattagaa
    32461 aaaaattagg acttactatg caggaatttg ggtacgaggt ttctaattct cctagaagca
    32521 ctgtgtcaac atgggaacat ggtggtaact taccgaacaa agccaaacta aaaaaaattg
    32581 cagacattgc gaattgtagt gtagaagatt tgctttttga tgaaggcttt atttctgaaa
    32641 aatcccaagt taaattgata aatgaactca aagaagaaaa ttcaaagcta aaagaaaaaa
    32701 taaaatacta tgaatgttta tttgatggta tagagagtct gctgaactca cgaaaaaatt
    32761 cctagttaat taaactagag taaaattatt tgtaggtgtt aaatatgtta gttggctatg
    32821 cacgagtcag ttcagatgat caaaatttgg aaagacagct tgaagaattt agaaaaattg
    32881 gtgtcgaaaa agtatttgct gagaaaaaat ctggacgtaa cacagtagaa cggccagagt
    32941 tcaataaaat gttgtcattt gtcagagaag gggatacgct tgtttttgag tcgcttgaac
    33001 gcttaggaag aaattctgat gaaatactag aaacagtatc ttttatagat aaaaatggta
    33061 tgggcttaat ggttttgaat ttaccaattt tagatacaaa atttggtgat ccaaacttag
    33121 aaaaacttgt tagaagctta gtaattaaca ttttttcttg gacggctcaa aatgagaggg
    33181 aggaaattaa gagaaaacaa aaacaaggaa tagcaattgc gaagaagaaa ggagtctata
    33241 aaggaaaacc ctacgaatat tcttctactg caaagaatcc acaaaagagg tttatctata
    33301 atgaaatagt aagaatgctt ggagaaggtg ttccgattaa gcgaattgca gaaaaaacag
    33361 gaacaaatag aaatttagtc tatagaataa agaaaagaat aagtgaatct gattgatttt
    33421 aagttctttg agaaatcaat gttacgagag aaggattcta agcctgtttc aaacttttaa
    33481 ggtgtacaat tatacaaaga agcttctaaa caaaagaatt aattttgtgg cagtcaagta
    33541 acgacagaaa tagaaaagaa agaggctatg cgagagtgaa tcaacaagtt aattgggtta
    33601 atgattttga aaaagaattt cgactgaaat tttttggaaa tcctacagca gaaagtacag
    33661 aagaaaaaaa ttatgactgg tcagaatttt aggttgcata ttcgattcaa taagtgttga
    33721 agataatagt tctcttacgc cacagtatac aacgttagaa tatgacgaaa acagattcaa
    33781 tacatttcct tgcaatacca ttcaagaatc aattgataag catgagtgat aattgattat
    33841 ctacaggaag gtgtttttta tgaaactaga gatcaaagaa gttgtctgcg attggggaat
    33901 ttatgtagac ggagaaacat atccatttat gatttttaat agtaaagcaa atgcacaaga
    33961 gataatgcgt atcatggagt tggataataa gcacgaaaga tttgattaag taaaaaaaat
    34021 ggagaatgaa tgtgaagcag tggaatacca aaaaacatgc gccaataata agtatatttt
    34081 aggtgcaatg ggattaggta aatcagcttc tattaaacag gtctacgaag aatcacagga
    34141 gaattgcgta tatgaaaatt cgaattaaag agtgagaata tgtgggagct aatttattta
    34201 gttttatact taataggaaa atcaactgaa tttgtatata acaataaggt aatatttata
    34261 ttgttcttaa tagtttgtat tatcgtattt gatgtctatg atttactaat tcataagaat
    34321 gaaaatagta atattggtag aattataatc acaaacttaa tagtaattac tattgggatt
    34381 acaacattaa caaataaagc tttaatatca agtatgattt taatagtgtt tgattttatt
    34441 atcatttata gtttgctgtt tttaataaag aaagtaactg aatatttaaa tcgttaggca
    34501 tgaaataaat tttaattgag gttgaattat agcggtaaat catacaaaat agaaatgtag
    34561 tcttgttaag cgtcttgact atctaatttt gaatgaggag ggttgtatat agaaaaaggg
    34621 tagttaaatt cgtagatcaa aaggctacga aggagaatat agaatgacag ctatttataa
    34681 agcactaaaa aattctaacg tatcagagta cgttaagtcg agagtattaa ataataattt
    34741 agattacatt ttagaaaatg gtgttgctga tttaatcagt aaattaagtg atcctataga
    34801 tatagatcat ttggtggtat ggcaagatgg tactttagaa gtatcaatat atggagaatt
    34861 ttatagtaga aataaagtaa ctacattcaa aaatagtatt agtggtcgag aagatttaaa
    34921 aggaatcaat aaaaatagta aattctatag aacaaataaa gaattgctag aaaaaatttc
    34981 aaagcgtgtt tttgaattgg tgaatccatt ttcaaaaaca cgtagtaaag aactttttgg
    35041 aattttttat gatggtttta gtgcaaaaag taatgtagaa aaattttttt attttaatga
    35101 ttcagcttat attgcggtta aagacagtaa aagaatccct gaagcaactt tagaatattt
    35161 agagccaatt aaattgtctg ttttttattc actttatgag aaagaaatcg ctgatgaagc
    35221 ggtttaaggg gagtaggatg agtaaaaaaa taggcaaaga gtcgttatcg ctcggattga
    35281 aaaaagaaat ttttaaattt aaaaatatgt atagtgagcc ggaatttaga ctcatttttc
    35341 aattagatat agtgagaggg ctgaaaatta gttttagttg tttaggttat ctggtttggc
    35401 tattcattgc tagagtagga tggagcaatg cttatagctt ttataaactg ttcgccggaa
    35461 ctgatcgatt aaaagaatca ttagaggtga aagaagcctt aaatatttta ggaagtcttg
    35521 ctttcagcct gtttattttt gctttattta tcttacaagt aggaaaaata atgatgtcaa
    35581 caaatgacaa ttatattaat tatttgaagc cttttcaaaa aggaataaaa atcatttgta
    35641 gacagggcac agttttattt ctacttagcc tgtatgagca tgaaattcat tttcaaaatt
    35701 attataatac gacaactaaa cttggtgcat ttttactcct atatttagtt agtaatatag
    35761 ctgaaaaaat gctgtttaaa catattgtaa agcaagtctt ttctgatatt aaaaaggaaa
    35821 gctattgttt aaaaacacct tatggaaatt taaaaaatgt tgagctgttt ttatttaaaa
    35881 tggatagtaa gtgggataaa tatatctata gaagtaaaga agtattttta actggtagtt
    35941 ataacgaaac tcttcaggag agcctgtacg acacaggagc aatatttaat aatgaaccta
    36001 tggttttgaa agatttcttt ggagattatg aactagtttg gaatccaaaa cagcttagtg
    36061 aacagggggc agaaaatgaa tttgctgaag ttcactaaca tagtgtacag aaaaacatta
    36121 tctgaaagaa gaacgccttc aaaagaaagt ataagaacga ttgggccgta cagaagacta
    36181 acgaaagatc gtaaaaaaaa ggaaagacaa tgaaaatgtc tttccttttt ttgactacaa
    36241 gtagcctgaa aatgaaattc caaaagacta cttgtagtct tttgtggcaa aaataaagag
    36301 ccaacgaaag ctaccaacaa tcgttgactc gtaagactgt tcgtagtaag aaaaatcttt
    36361 ggcaatccac gaagtcttta tttcataatt tatataaatg attatacagt cattttcctg
    36421 aatttgcaag taaaaaagct aagaaatatt gtttaaacgt ttccttaaaa gaatctttaa
    36481 ataaattttt ttccaattga aaacatgact acaagtagac tatttctttt attctgagtt
    36541 gactacaagt agtcaaaatg atataatatg tatatcaaga aaggagaaac aaaaatgtat
    36601 aacgtaggag atcaaataga tgagatcgta aaaataggta atgttaaact tgataaaagt
    36661 aagtactgta tttcagaaac cgaaataatt tttaatactg aattagggta tattttaatt
    36721 tggaaattgc cttttccaaa agacgaagaa actctgaaaa aaataaatac tttaaaaatc
    36781 agatattgtg tttatgaagt tattgataaa aatacttatg ttataaatca agtaaaagtg
    36841 atggggtaaa aatctttaaa aaaactcttg ttaaaagtaa ttctattagc ttataatgtt
    36901 ggtattagtt ctgaagccaa aggaacacta aaaaattcta gtagaaaagt tagttacaga
    36961 ctctctacta tgtatgaatg taacgaaaaa aatagcgaaa aagataatta aataagacta
    37021 ccaatcttat ttaatggaac ttctgtagta agaaaagcga tttggcaatc cacgaagtcc
    37081 accaagatga gctaccaact cattttaatt gttgcacgtt taaagtttag catttaagtg
    37141 cttactctaa aggcatagtg taattttagg actccttatt acggaatcta aagttaccct
    37201 atgtcttttt tgctattcaa aattgatagc aaggagaaag tgcaatgttg aatagttgcg
    37261 agtatgcgga cgttttagct aaaattctta aaaatggaat taaacagttt aatagcaaaa
    37321 atctagttgc ttttaaaaag aatagcaata agattggtgc tattgccgga tttacttcta
    37381 aaacaaacat gataaagact aaaggtctta tatatcgttc tattgatcgt gtcttggaag
    37441 attcagatgt attaacacac tggactccta acgtgtattc atggcttggt ggcggtgaaa
    37501 acaaaacaat ttttggtcac aaagaagcta acttaattca gattaatact tttgtagcag
    37561 atattgacta tccagtagga gaaaagaaaa cggatttgaa tttactagtt ctttatctat
    37621 tggaagaagg gttattgcct acattgattg tagatacgcc aaaaggttat cattgctatt
    37681 ttctgattca aaactataac caagaaactg attcatttga taaggcaagc tatatttcta
    37741 attcaaatga ttttaaatct ttgagagttg ctaaaagaat atcagaaaat atcagaaaat
    37801 ctatccaaaa tcgtttacca caagtcgata tgggctgtaa tcattttggt atttttagat
    37861 ttccaactaa aaaaaatatt gtacattatg aacctaattt cgtagatacg tttgaagggt
    37921 atttgaaatg gtcaaaagac tttgaagaaa aagaatatgc tttaaagagg tctaacttgt
    37981 cattattagc tcctaattct actggcaaga aagggtctaa acgacaaatt gatactaaat
    38041 ggtacgactt tttaattcat acggatattg ctgaaggaga tagaaataaa actgttttta
    38101 ccttagccct ggcatgtaaa tcaagtggct tatctattgg cgagtgtatg gatcaattgg
    38161 atcaacttca attcaataat gatttgtcct attctgaagt tgagagaaca ataagaagtg
    38221 cttatcgtgg cgattacaaa ggtgctaaaa gttcatatgt caatgaaatt atcgaaaatt
    38281 atgctacacc taccgagttt gaaaaatact caataaatgt aaatagacaa gctgttaaac
    38341 gtaaagggaa tcgtgtcgat ccgtctaatt gggtgaaatt tgctaaacct agagaagaac
    38401 gaaaatatag tcattttgaa gaaagtaaag ctgatttatt agcttactta gaaagaaaac
    38461 aaagatcatt gaaaaaaaat gagttgtttt taagtgtctc tatgggaact atatctgaag
    38521 aaacacaaat tcctgtatct acgttaaagg tgattttaaa agagcttaga acggcgaata
    38581 cagtgatatt acaaacgtct cgtggtcggt atggatcgac taaaatagca acaagcaaat
    38641 ttgtggaagc taaaatatta agtacagtta ttcagaataa aaaagataaa caagtatttg
    38701 tcttagaatt attaggaaca gcaaatagcc acgtagaaac gattttaaga cgttatgaag
    38761 acaaaacagt accgttccat gcgaacatac tgaaagaaag agaaaagagc aaacatgcgc
    38821 caattagagg agctaataca ggttagagtt ctatttattt ttttgatttt taaatagcta
    38881 aattgccaat taacatatct agtgtttctg ctcactccta ttcctgtttt aacgtatact
    38941 aatcattagt agttagtact ctcttttacg tatggagtgc atagaactat ttttacttgt
    39001 gtcttttccc ttaatccacg tgtacggaat acagcttata actgcgtatg cagttatgtt
    39061 tgaaggagga agattttctg tggtaattaa gaaatatgtt tactcacacc cgatcaatgt
    39121 atttattatc ggtaagctag gtttatctgt tgaggtgttt tgtgagttat atggatttaa
    39181 acaaggaact ctatcgtctt ggattactag agagcgtgag gtagctgatt tgcctatttc
    39241 ttttttgtat gctttgtctc tagcttcagg agggaatatg aatgaggttt atgattgttt
    39301 gtgtgagtat gaaaaagagt ataaagagta tttgaaaatt tcagccccaa aacggaataa
    39361 aaaatatatt gaagattaga gaaagaagaa aagaataatt tgctttttga ctacaagtag
    39421 actgatagct actctgtttt ttgatagttt gatattggct gtttttttgt tagaattaat
    39481 atatatcagg taaataaaaa aagggggcta ttaatgaata ttgatgggat ttataatgaa
    39541 tcagatttta agaaaggcga tatagcggta atacgttcag agtatgattt tccttcagaa
    39601 ataggaatcc atacagtaga gggaaaaact gtttgtcgtt attggggtag aaaagggaat
    39661 ttaatattat tattagatac tgattcaggt gacaaattaa agttttgttt ttggcataat
    39721 actaattatt gctgtgaacc tattccaaaa agattgattg atgtagataa ggaaagtgta
    39781 agatatttag ctgatggaac taggattaga ttaacgtatc agaagtctga aaatgcttca
    39841 attactcgtg taagagatat tgttgtaatc tagtgggagg tgaaggatta tggaattaat
    39901 accttatgcg tatcaacatt tgtataaggc taaatcaatg aaagatggta atgaagttgt
    39961 tggagcgttg atttgttgtc caccattttc ttatattgct accattgaat ctatgaagaa
    40021 gatgtgtgtt gatgaattga atgatggtga agttaaaaat ttaaaattaa cacgtgtatt
    40081 agaacgttca attgaagaat ttaggtgaag gagagagtat ttatggcaac tgtaatttta
    40141 gcagaaaaac cagatcaagc agagaaattc gcttttgcgt tagccgataa gaaaattcca
    40201 aaaagtggag ggaagtttga atttcaaagt gaggtatttg gagatacgat tgtaacttgg
    40261 gggataggac atttagttgg attatcaatg ccggaaaaat atgaatggct acctaacaaa
    40321 gaaaaatggg atttagctaa tcttcctttt ttaccaaaaa tggatgagtt gaagtatgaa
    40381 gtttcaaagg gaaagagtca gcaatttgcc gtagttaagg cgtgtttaga aaatgctgat
    40441 caaattatta tagccactga tccagatcgt gaaggagaga atattgctta taatattttt
    40501 aagttgtgta agcaatctat ttttaagaag cctatgaagc ggttgtggat taattctttg
    40561 gttaaaagtg aaataataaa gggatttaaa aaccttagaa atgcagagga aactatttct
    40621 ttctttgaag aagcaaatgc acgacaaatt gcagattatt tagtgggaat gaattataca
    40681 gaattgtata cattaaaatt gcaacaaaaa ggcttatctg gggtggtatc actaggtagg
    40741 gttcagacac ctgttaatac attggttgtt gaaaatgatt tatcaattaa aaatttcaag
    40801 tctgaaaagt ataaagtgat tgaatgtcat actgttgaca gagagccaaa agttatattc
    40861 aaaaatagtc gagaatactt caatttagat gaatttgaag cagacactaa aaaatacggt
    40921 ttggattccg ccagtatagg aattgtaaaa tcagtagaaa aaacattgaa gcaagtagaa
    40981 ccacaaaaat tatttagttt aggggggatt caagaatacg ctaataaaaa atggaaatat
    41041 tctgctaaaa aaacagataa aattatccaa agtctatatg atcgtggata tttatcttat
    41101 ccaagaaccg atagtgaatt gataactaca aatgaatttg agtatttaaa agcgaattta
    41161 gacgtgtata agagtgtttt agggatcagt attgatacac cttgtttaga gcctaaaaag
    41221 cggtttgtag ataatgacaa agtattagag cattatgcac taataccaac aatggatatt
    41281 cctgatatag caaatctgac attagatgaa aaaaatattt atgagatcgt tactaggcgt
    41341 gcgtgtctaa tgtttgcaga accttacaag tacgaaaata caaaagttac attagatgta
    41401 aacggcttag aatttaccac aagtggtaat gtacctatat ctttaggttg gaagcaagta
    41461 gatactaatt tagatgaatc tgatgataaa gaggaaacat tacctaaatt tcatgaacaa
    41521 gagacaataa atatagatat tagatttatt gataaattaa ctaaggaacc taaaaggttg
    41581 actgaaggta aattattagg taaaaccggt attatggcga aattagggct aggaacgccc
    41641 gctacacgtt ctaatattgt agacactctt ctaaataggg aatatattaa gatagaaaac
    41701 acgaatgttt atcctactcc aaagggatat ttattatggg atttgacaaa gaataaagac
    41761 ctattgattg gaaaaccaga aaatacagcg atatgggaag aatcacttgg gaaaattgcg
    41821 caaggtagct atacacagga agctttttta agaaatatct ataactatat caataagact
    41881 gtttcagatt tgaaaaaagt agaatttact tcggattatt tagaaaagac tgtaaatcaa
    41941 aataaatttg atataggtag ttatcaagtg gaagaaaaga aaaaagttta ttctatttta
    42001 aatattacta gtggtgaaca gttcgtgata tttaaaaata tatcaggaaa agcaatcaat
    42061 aaaaaagttc ttcaagaact attactaaat aatcgtacag ataaagtcct ttccggcttt
    42121 aagtcaaaag aaggaaaagc ttttaatgca agattacttt tcgatccaaa tgtgatgaaa
    42181 gtggtaatgg agtttgaaaa gaacagtcca aaaggcgata aaaagagcaa acacgataca
    42241 gtaaatggtt atgaaatagt tgaaaaagca aaagtatttg aaataaaaga attagcaaca
    42301 ggtgaaagtt ttattttcta taaaaataat agtgggaaaa ctttaagttc aaaaacagtc
    42361 aaagaattgt tagaaaatgg gaaaactaaa gagaaagtaa cgggttttat aagtaaagac
    42421 aataaaaaat atagtgctta tcttgtcttt gataataaaa acaaagttat aaagaaagaa
    42481 ttttaattct tagtggcgga aatcatttgt ttttccgctt atttttattc aaaagtgccc
    42541 aaaatatagg tatactgaat taaggataaa tacaaaacta gttagaggac agttgaaaaa
    42601 atacaaacaa attagattgc tattttgtta aattggaagt agaataatac cgttttgata
    42661 tgtatagtgt gttttaccaa taaaattaca taaacgtgaa tatattttta tgaattaaat
    42721 gtaaaatgag agcaattagt tttaaaaaag attataggct gttaatctta gcatatataa
    42781 tccattggaa agggggagat ccaatgaatc taaagaatac aaactcaaac aaatctacac
    42841 tatatgtaat ttcagatgat tatataaata agctgaaaaa ggtggactat cgtgtccaaa
    42901 acaactatcg agaacaacga ttatatttta aatcaaactt gaaaatttct aacaaaaatg
    42961 aagaaataaa ttattatgta ccattggctt cagcaaaaga aaatcaacgt tctttgacta
    43021 ataaatcagt gtttaagatt tatggtgatc gagaagaaaa ggacttttta ggagtacttc
    43081 atataaataa tatgattcct gtgccaaaag attgtgcaaa agtatggaca cctaatagcc
    43141 caaatgttga tgagaagtat aagatgttag taatcaaaca ggcaaaatat ttgaaattac
    43201 atgagtctga aataaatgaa tcatgcgaat tactttataa ttctaagtta ggtaaacttg
    43261 atcctagtta ctttaagaaa aatcgtaaag aagtaattac ttatcaaaaa ataatgacga
    43321 atgtagaatc attggaagct gttagtatag cagaatccca aagaaatatt catgtacaaa
    43381 ctcaaagtat agatgtagag taagataggc taaacctatc ttattttatt attctattgg
    43441 atattatgat acattgaatt ttaatcgaat atgtatttaa atgttattat actgtagaag
    43501 ataaaactta aaggatgatt tctatggcga gaccgagaaa atacaataca gaagaagaaa
    43561 gaaaagaagc aatgaaaaag gctaggaaaa aatgggttga aaaaaatcag gaaactattg
    43621 cctatataag agccaaatca tttgctaaaa aattcattga aatgtctgaa gatgaagata
    43681 ttgaattgtt ggaaaaatgg ttagaagatc ggaaaaataa cggtcaaaat gatgaataat
    43741 aaccattgac tacaagtagt caatggtgta gaatggtttt agggatagaa atatcccttt
    43801 tctaaaagtc taatgactac aagtagtcga tagagggatc gggaataaaa acagacgatt
    43861 atggcctaaa gaaaggagga atatgaatat tttgaggaac gatttattaa atgagcgttg
    43921 ataaatttca ctaaatattt tcttaatatc tatgtattgt tcaagcgtag aaaaaaatat
    43981 tgaaattatt acaaaaccgc tcataatgga aaataacgaa ttatattaat gaatcgttca
    44041 cttttgacct tttttactag atttttttgt aggactttta gagaattttt ttgttatctg
    44101 attataagga ggagctaaag ttgatagaga atagagtact ggggttcgta gagtgtaaag
    44161 ataatttaga cgatacttta gaagtccttg aaagtattat atttaacacc aaagttctgg
    44221 atttgaaagc aattaatggt gatatgacaa cacatatcat attagatgaa attagcgcaa
    44281 aagagattgg cgaaacttta atagcatggg ctaataaaga gctgtaaaag ataattttaa
    44341 aataaagtgg ccaattgact acaagtagtc tgtatagtat aataaattat caaaagtgag
    44401 gtatacatga tgaaatcaaa ttttttggga tatgtaattg caatcaacat gtttaaaggg
    44461 ggagttggta agtcaactct tactcagcta atggctgata ttctatcggc tagaggcttt
    44521 aaagttttag ttattgatgt tgatccacaa ggaacagtaa ctaaaaagtt tcaaagacaa
    44581 tatgatttaa aagttgttgg gaaaatgaca ttgtttgaag cagtaattaa tatgtctttc
    44641 ttagactgca tttctcctgt taaagaaaac ttagatattg tgcttggttc agaacaaatg
    44701 tcaaggttta ccaaagtatt aagagatatg tggagaagta ctggttttac tgatgaaggt
    44761 gaagaagtct tttggaattt gtttaattat atgatcggta atgataattt aagagatcaa
    44821 tatgatttta ttttgtttga cactattcct acagtttcag aatttacaga taacgtttac
    44881 gtggcgagtg attttttagt aattcccacg caaactgagc aagattctat agacaacttg
    44941 catagtacgg ttactaatta tcaaactgct gtaaaagaag taaacggaga tttagaaatt
    45001 ttaggtattg ttccatatct agtggatact aaattaaaaa caggattaga acttttatca
    45061 gaacttcaag aagaatatgg agacttagtt tattctcata ttgtttcaga acgaggcgta
    45121 attaaacgtt ggggtagaga aggactaaat aaatctatcc cacattctaa aactgcttat
    45181 agcatgtatg tagacattgt agaagaaacg ttagtacgtt tagaaaaagc tacaggagaa
    45241 aatattttag aacgtgttta ggaaaggtgt tgcatgatgt cgaaaactaa aaaagtaact
    45301 agtgccggca gtaatggttc gggtaatccg ttcggaataa aaagcggtag tggtggattt
    45361 aatataggac aacaaatgtt aaaaggtaaa gctggcatta agtctactgg tgataaacgg
    45421 aaatctgtta gggtaccagt tgaattatac gatgaagttg ttaaagattt atcatacggg
    45481 gctaaatatt cattaatgac agaaatttta gctttatttt taaaagaatt tgaaacacat
    45541 ggaaatagta tagttactga ttttggcaag ttgaaaacga gaccagtaaa aatttctgaa
    45601 gaagccttta aagttttgaa agttataaaa tttgaaacag atcaatctaa tactaatatt
    45661 attgcttcag ctttgacatg gtatcttgat aaaagaaaag gaaaagcata atgaaatgag
    45721 gtaagactat ggatcataaa tcaaattatt catacaaaga aaattatatt tggaagtatg
    45781 tagtagccgt ttttctactg gtaggtggaa ttattgcatt ggttaaatgg gctataattc
    45841 ctaatgcttt agtatttatc aattggtttg tccctaattt ttggagtttt tttggctata
    45901 tattgataat ctggtttatg tttaaagtac tctctttttt ctggtcgcct gtatattctt
    45961 tgcttggaaa gtggtcgtac ctaattttaa tagcgacagc tatttatatc attatgcaga
    46021 ttaactaatt atgcagattt tagaagatat taaaatttat tggaaaagga taataggcta
    46081 tacattagtt cttcttgtag taaatttatt cctttcgatg atagcgttgg tctttgttaa
    46141 tcaaagaaaa gacaatgtaa ctgaattagt aacgtttatt tcgtttttca taagtgggat
    46201 ttttgctcct ttctttgaag aaaccttaat gagaggaatt atccaaaacc aattggaatt
    46261 aaaaacaaat ttgtctacaa gaagcatata tataattgtt gcaattttgt ttagtctatc
    46321 ccacttaaat ttatatttta ttccttattt tatgacgagt ttaattttgt cttttgtcta
    46381 tgataattca gataaaaggc tgattgttcc ggttactatt cattgttttt acaatttaat
    46441 tgtaatactg ttaagtgtag ttttttatac ttgaaaaaaa tagacgaaaa cctaaaaata
    46501 caaggttttt atctattttt tttattttgt ttttatctat caggttgata gaaattgtca
    46561 taaatgatat aattaagtat gaactgattt agtaaaaaaa ttaaaggagt gatagctgtt
    46621 ggcaagatca agaattgcta aaattgaaca gactaaaaag gataaaaaaa tttctaaaaa
    46681 taaaacaaaa ttctttaaag ctgaagatgt taagaggata gcatggtctg tgaaaacatt
    46741 tgatgaagat cgttatgtta aagtttcaat gaatggtcta tttgtacagc ttggtaactt
    46801 cagtaatttt aaaacgattg atgaacttta tccggaaata agaaatattg tggatagtaa
    46861 aggtttaatc gtggctaaac ggaaatcaag aaactctggt cttgcttact gtaaaaataa
    46921 agggatcatg attccggctt aaatcagtga aattgttctt tgaaaactta atactactcg
    46981 tactgtagca atgttgctat gttacagata aaagcgtaag gctaataagc aaaatagcaa
    47041 ccaagcatac tgttatttcc tttgccaaga ggtatgtaaa tacgttagca atagaagtga
    47101 taaggttagt atttcacgcc aaaaaataca aaagtcgatc cattgaaact actaattatg
    47161 aggtggcgta aatggtaatt attcagaatt tctatctagg aagaacctat gaaaaccgtc
    47221 ctagagatca gaatattgac actaaaaaat tcagcacagt aataaatgtg ctagatacag
    47281 ggtaactctt tactacaaga aatgtagtaa agagttgtta tgattcttta ttacatttct
    47341 ttctaaagga agtgtgataa tgaaaaaact aaaactgatt agcattgctc tattcagcct
    47401 aatcactatg tcaacggctc gccaatcaat tgtttcggct gaaggaacgt ctacgaaagc
    47461 agtagtagaa gagtctggcg ataaaaaagt tgctatagac gacaaagtga aaaacgaagc
    47521 ggaaaaagcg actgtggttc aaggggcaga cggcttgatg tatgtggtcg ttgatgaaaa
    47581 tgatcctgaa aaattgctag aagctgaatc tcctttgaaa aatcaacaag aaaataccgg
    47641 cgctgttgaa gtcggtgttg atgaaaagag acaagaaaag gctgataaag ctaacgaaaa
    47701 agtgaaaaac tttgacgata ttgattacaa cgatattagt tcgttgcagt cagcgttgaa
    47761 tgatccgaaa ttcccttttt tatcggaaga tgaattaaat gaaaaattgc aaaagacaaa
    47821 gaatacattt gagtctgaag cgctaatgaa aaagacaagg ggatatttca gtcaaaggat
    47881 tttagagtta agcaataatt taaatgacgt accgaaaaga gcgaaagtga gtcggcatgc
    47941 tttagttagt aaccgtgctt cacaagtaag tgaaacacga ataaaccctc caaatggtta
    48001 tccgtgggtg atttatttaa ttaggagcaa tggttatagt tatacagaaa attatgctat
    48061 tagaagaact attgatggga aagaagcttt ttgtttacag gccggtgtac aagcgacgaa
    48121 tacatacact ggttcaacaa gtggttatct ttctaattcg caaagagaaa tgattagttc
    48181 gattttatca gcatataaag aattaggcgg ttgggctaat aatgatgccg gaaaacaaag
    48241 atggatagca actcaaatgc ttgtttggga aaacagtaat gaaaagccta aaagtataac
    48301 tgttacgcca aattggaaaa acggagctac taagtggaaa aatgatttag tggctcgtgc
    48361 aaatgctatt agagtaagaa caaaatggga ttctacgtct aagacggttg atgagggaga
    48421 taaagcaacc tttaaagtaa ctaatactta tggagatcat aatttgcatg tgaaatctgt
    48481 atctggtggc ggcaaagcta ccataagcaa tggtacttta actgttgata ctacaggagc
    48541 cactggaaac aaaatcactg tagatatgat taaaggttct cacccttcag acgcgcaccc
    48601 tacaacggta tggagtaatg gttcttatca aaagcttgtt accggttctt tttacattag
    48661 tacttctgtt acggtaaatg ttaagagaaa aggaactgtt gaagttttaa aagttgattc
    48721 agaaacaaaa aaaccattat caggagcaac atttagattt agctactcag gtaaaacaaa
    48781 agatgttact actgattcga atggtaaagc aaaattaact gaaaggttga aagctggaac
    48841 tgtagtaaaa gttaaggaga taaaagctcc taatggctac caactagatt caagcgaatt
    48901 ttcaattaca gttaaagaaa atcaaaatgt tactaccaca agaaccaata agaaatccac
    48961 aggttctgta gaaattgaaa agataggcga tttagatgga ttaggactac cgaatgtagt
    49021 attcacgatt tataattccg ataacaaagt tgtaaaagat aacttaaaaa cagatagtaa
    49081 tgggaaaata aaagtcgatg aactgcaatt tggtaaatat tatgcagtag aaaaacaagg
    49141 tgttactggt tatgatcccg atggtaaaaa atacaatttt gaaataagtc aagatactcc
    49201 ttttacaaaa ccggctaaag tgaaagtaac aaatatttat gaagtatcca taagcgaaaa
    49261 agtatcggac atgaatgaaa gtcaggtatt aaaaaataat tggtctgctg atccaaacga
    49321 ttatcttcaa tatgacatta caactggaaa tctaaaaaaa tcgggagaaa gaaacgtcca
    49381 aagtttcatt atcgaagggt tttacgacaa taagaatgta gatgtgtcaa aaagtgaagt
    49441 atatgttgga tcaacaaatg taacaaactc ttttgacatt aataacgata ctaacaatgg
    49501 aaaagtaatt gctaaggcga agacaagcgt attaacgaat aatgattttt ataataagtc
    49561 ctataattta cggatcacta tgaaaattaa aaaatctact cttgaaaaca ctgaaaagca
    49621 aaaaaattta acgattgtta aaaatagtaa agttactgtc ggttcaaaaa tctctaaatc
    49681 tgctagctct aatgatgtag aaaccgtttt atattcaaga aaagttacta tcaatcatat
    49741 tgatgaaaaa gacaaacacc ttttgaaaca agatattgat tataaatacg atggggaaac
    49801 gtatgaatat aaacctagaa ccgatttatt tgataaagat ggaaacaatt ataaatctga
    49861 tgtaatccat aaagggaaaa ttgatggaaa agatatagtt ttaaacactc cctatcatat
    49921 tccggtactt tctgtgaatg tggatcggat tcaaattgat acggctagag ctgttaaaaa
    49981 tggctattta cctacaaaaa tagaactaag taaaaaagaa gaatatgaaa aagaattaga
    50041 aaaaattgta ttcaaagtta aaattacaga tatagataac aataaagttg tttatgatga
    50101 aaactttaaa tacaaagaat ttaatagtca tatgtcgctt gatttaccta cagaatattt
    50161 aacaaagaat aaaaaaatca attatagtgt tgatattctt ttagtggata atccagataa
    50221 aaacaagttc gaaactgaaa ctaaagattt aagaacgatc ggttatactt cttctgaaaa
    50281 agttttaaca aacaaagata tgacaaataa ccaagtcaac tattcagcag tagttagaac
    50341 agtgaaagaa agagagaata ataatccggt caaagagttc aatgagagta tcaattataa
    50401 atttactgat agcactaaaa caaaaacagg atatggtata tcagttgatt tagagccaac
    50461 atatagaaat gaaattggga aacaaataga tatgaaagtc tatagttatc cgatgaatga
    50521 attgattgac agcaaaattg acgaaatcta tcaaagtggg ggaaaagaaa cagaagttaa
    50581 gatggatcgc ttaaagaatg atggtaaagt tgagtcgggt attagtactc aaaatctttc
    50641 attccaattt ccacatatga atatcgaaag aaaaactgga aatatatatg ctgacagtca
    50701 aagaaatgat gaatctatta agtatgaatt gatcgatggc ggtagaaaat tatatgtgcc
    50761 tatttggtgt gatttgggaa attattctat tgctatcaaa agtagtaact ttggtggtaa
    50821 ctatatctcg ttggatatga accagaacat agatgtttat gcttatatgt atgcaacgat
    50881 agatagtgaa acaaaaaaag atgatgaatt actgcttgaa cctgtttatc cagagtctac
    50941 tctaccagat ggttggagca aaaatgagat tgattggctg aataaataag tttgaaaagt
    51001 ttttatctat ctgatagaat taaataatga tatagggatg gtgatagaat gagggttcaa
    51061 agctatggta acagtgtctt tgatgttaaa agagaatttc aagattctag aagaaaaacc
    51121 aaaaagctga tagcttactt cattctatca gctatcgttt tctatattgt caagtttgtt
    51181 ttggaattaa actcaatagt attcacagat atggttcata aaatgttaaa tggagaacct
    51241 attaatttca actttgatta catgcttgaa aaagcacaaa gcaatcaaat tgtggctttt
    51301 atcgtgagta tctattattt tattgaaaaa tctatttttt ctttaaaaga ttttttcttt
    51361 gaaatgctta ccaaactaac aacgttttac aataaaattt caaaaaatta aggaggaagt
    51421 ttgaatgtta gatcaaaata cagacagaag ttggtggatg attggtgccg tgatcgtagg
    51481 tgccatctta atcgggacag ctaaagtagc ttttcccgaa gtgtttaata tcgtcattac
    51541 atttttcaaa aacatgatcc ctacaaactt aggatagttc cactaaaaaa ttcacgtagt
    51601 ttgatgcgta gaaaaataat aaagaatgaa aaaggctaca taaagtgatt tatgtagcct
    51661 tttttttgga tggaagtgat gtaatgctaa gagatatgcc caaaatgatt cttttaatgt
    51721 ttgttgggtt ctttttaatt ttagtgattg cgtactattc attaaatggc tatacacaag
    51781 attcgtctgt gaaaggtatg caagaaacgt taagaactac agcaatagca aacagggatg
    51841 atagtattcg agtagaaaaa ggacgatttg ctttaattaa gtctgatttt gaaaaagatt
    51901 ttaaagaaaa atttgggaaa agtaaaaatc taaataatga aaccgctgat tataaatttg
    51961 attatcttac agatgggaag gacggtatta aagcaattaa agtgaaggtt gaaagtggat
    52021 caaaagaata tcaagcaact tgtattttaa atgttgcaaa tgattagagg tgtgaaattt
    52081 gcgtgttgta gaggaaaaga agatttctcc aaaaatcgag gaaactccta aaagtaaaat
    52141 taatatcgca agtattatta aaaaaaatgg aattaaagaa aactctgaag cgatagaagg
    52201 aaaccttgat tttttaacta agcttttaga agaagatagt ggaaattatg aaccaccaat
    52261 tgaagatgca aaattaaata tgattcgtga tgatttaacc agaaactatt cccaagaagt
    52321 tttacaagct ttaactgatg atgaaattag gcgaaaactt gtacaagttg ttttgaaaga
    52381 acatggtact ttctttaaaa aagataaaga ggttgcagaa tatgtagtac gtgaatgtat
    52441 tggaacaggg attattgagc gaattatgac caacgatgaa attacagatg ttggttggaa
    52501 tggctctcaa cttagcattg aaactaactc taacaaatgg ttgtttgacg gtgataaatt
    52561 aaatatcacg caagagtata ttgaacgtgt tatttctaaa tatgctgttg taaatgatcg
    52621 ggcttttaat agtggtaatc ctatcatgga tggaatgttt aaaaatgttc gtatatcagc
    52681 tacacacata gataattcac cagatggctc tacgttttct atgcgtgtgg caaggcctag
    52741 attagcattg aataaagaaa actttgaaga ttttgctcct gattatattt tggagctatt
    52801 tgagaaaatg atgaaaacaa aagcaaatat ctgtatatca ggggagacag gtacaggtaa
    52861 aacggaactt caaaaattac tgctaagttt tattgataat catgatcgta tgattatgat
    52921 tgaggacgtt caagaaactc acgctaaaga attatttccg gataaagata ttttctcttg
    52981 gatcactact cccaaaaaag caatttcaga tttagtaaaa gcttctctta gaaataatcc
    53041 acgatggatc attgtttcag aaacacgtgg ttctgaagct tatgaaatgc ttcaagcggt
    53101 tttgtcaggt cactatgttg taacgacact tcatgcggtt aatgcacgtg cgatacctag
    53161 acgttttgta aatatgtgtg caagtggttt taaaataaac gaaaatgcgg ttgaggaaga
    53221 cataaatcgt tatttcgatt ttggtgtcca tatcaaaaaa acagtggttg atggtaaagt
    53281 gatccgttat ttgaatgaaa ttgttgaatt ttctgctagt gaaccgacta cagtttttaa
    53341 gcaaaaattt atcaatggaa agtttgtcat tgaaaatggt agtctttccg aagattttaa
    53401 agaaaaaatg gctgaaaaat ttattacgtt tgaatttcct gaagatcaaa ctaatacaga
    53461 agaatcactt cctgaagaag aagaggtgat ttaagttgaa agtacaggct atgacaaagc
    53521 gaaaaggtct catggatgtt tcggaactaa acgcctatca agtagcgtat ggtaaaccgt
    53581 tagattatag agattatttg aactatgttg gattaccttg tttgtttatg ggtggctttt
    53641 cttttgcttt atgttactac tggtggattg ctttgatttg tggagtaatt ggaggcgtat
    53701 atggctttaa agttataatg cctaaaagta ttaaacgctc ttatgaatta aagagtttac
    53761 aggaaagaaa taaatttatt aacaacatga ctcaaatttt gaccgatgat agtaaaacag
    53821 ttactagagc gttatctata gcaaaacagc gaacaaaagg tgaattaaga gaagatattc
    53881 aaatcttaga atcacgttta caaggtgctg ataaatttca gattgctgaa gcttttcgtg
    53941 aaatcaacaa taaatattat agtgatgttg tttttacaca atactttgag caattggaaa
    54001 cagctattta cgaaggtaga aataattcag atactatgaa gcaaataaag agctatcata
    54061 atgatgtgaa acgtaaaaca gaaggtttta tgaaaatcaa agacggctat cttcaagata
    54121 tgaagcaaat gatgtttatt gtagctgttt ttattggagc tataactttt gcttttggtt
    54181 tttctacttt ctatgaaggt tttgctcgat cacctatcgg atgggtattt ggatctattt
    54241 actttttgat tatggttagc ttcatgaagt catttttcaa acattatttt gatgatgaaa
    54301 taatgagttt gggggtaagt aattaatgaa agttaaggct ttaaaaaaga aaagaaaatc
    54361 aagtattagc cccttgaaaa ttacgaaaac agaacataaa agcttttgga ttaaattact
    54421 aggtgatgtt tattatcaaa aattacgtga aatgaacaat tccaatattg cgattattaa
    54481 gtggcaaaaa caacggttaa aaaagtcatt gatttttatc ctagtcggat tcttaatgta
    54541 tctattttta gggaaagaat ggtattactt agccggtgga attgctactt cagtaggttt
    54601 ttatgtttgg caagcaaaat caatcaatgg tatctataat caatttcggt ttgaacgaca
    54661 cttgcaattt agtaaattta cacggctatt gatcccctat ctgaaacaaa aaaaagatgg
    54721 cggaaattta tatggtgttt ttgcaaaaat cgtaaaaaga ctagattatg ataccgataa
    54781 aaagctatta atgaagctta tgcaagaaat gacagatcag cctaacgata ttagaccttt
    54841 tacggaatat gcagaacaga cttctggaac agacatgtcc gtattattta tgtctacagt
    54901 ttatgatatt cgacaaggtt cggcagattt ggatgttatt gaagagttgg atcgtttagc
    54961 ttctgaagag ttaatggccg gaatcgattc aatcattgac tataagtcga ggcgttttgt
    55021 cttctttcct acaaaaattg caatgacttc atttatttta gttgtcggtt ttgcagtagg
    55081 cgttcttttc atgaacctaa aagatattaa ctttgggcaa taaaggaaag gagaaagtca
    55141 atgcaagaac aatccgttat ggaaatcatt aaatggttta taggtttaat gatgattatg
    55201 gcaatggttt ctataggact tttttgtgtt caattacaag atattaatac tttcaagcaa
    55261 caagtaaatt atcaaattga acgaaaagga ggtctgacga cagaagctgt tgaagcaatc
    55321 gacaaatatt cggctactaa ttatgataga cgttttacaa ttgaaagcga taagttaaat
    55381 cagaaagtat cttatggaga agaaattgat tatacgatca aagcaactat tccaattcaa
    55441 attttaccgc ttcctgatgt aactttatcg tttaacggaa atagtgtttc tcaaataaga
    55501 tgagaggaag gataaaatgc aagagaataa tgtttccaga ataatttatt tgattggcgg
    55561 attgataatt ttatccttag ctattgccgg tcttgtagag cattggccgg aaataaagtt
    55621 attaataaga aacttttacg acaataaaat gattaaaatg taggaggtat agatttggaa
    55681 gcaattcaag aaaatcgtaa ggataatcaa gaaacaagtg aaaaaaac
//
LOCUS       DACGMI010000010        54254 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.010, whole genome shotgun sequence.
ACCESSION   DACGMI010000010 DACGMI010000000
VERSION     DACGMI010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.010"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(79..765)
                     /gene="gpmA"
                     /locus_tag="IXT46_000711"
     CDS             complement(79..765)
                     /gene="gpmA"
                     /locus_tag="IXT46_000711"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAQ4946647.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(937..1518)
                     /locus_tag="IXT46_000712"
     CDS             complement(937..1518)
                     /locus_tag="IXT46_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4946648.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(1651..2334)
                     /gene="rpiA"
                     /locus_tag="IXT46_000713"
     CDS             complement(1651..2334)
                     /gene="rpiA"
                     /locus_tag="IXT46_000713"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAQ4946649.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            2653..3066
                     /gene="rpsL"
                     /locus_tag="IXT46_000714"
     CDS             2653..3066
                     /gene="rpsL"
                     /locus_tag="IXT46_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAQ4946650.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            3150..3620
                     /gene="rpsG"
                     /locus_tag="IXT46_000715"
     CDS             3150..3620
                     /gene="rpsG"
                     /locus_tag="IXT46_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAQ4946651.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            3714..5801
                     /gene="fusA"
                     /locus_tag="IXT46_000716"
     CDS             3714..5801
                     /gene="fusA"
                     /locus_tag="IXT46_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAQ4946652.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            5973..7160
                     /gene="tuf"
                     /locus_tag="IXT46_000717"
     CDS             5973..7160
                     /gene="tuf"
                     /locus_tag="IXT46_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAQ4946653.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            7567..7875
                     /gene="rpsJ"
                     /locus_tag="IXT46_000718"
     CDS             7567..7875
                     /gene="rpsJ"
                     /locus_tag="IXT46_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAQ4946654.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            7906..8535
                     /gene="rplC"
                     /locus_tag="IXT46_000719"
     CDS             7906..8535
                     /gene="rplC"
                     /locus_tag="IXT46_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAQ4946655.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            8563..9186
                     /gene="rplD"
                     /locus_tag="IXT46_000720"
     CDS             8563..9186
                     /gene="rplD"
                     /locus_tag="IXT46_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAQ4946656.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            9186..9476
                     /gene="rplW"
                     /locus_tag="IXT46_000721"
     CDS             9186..9476
                     /gene="rplW"
                     /locus_tag="IXT46_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAQ4946657.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            9515..10348
                     /gene="rplB"
                     /locus_tag="IXT46_000722"
     CDS             9515..10348
                     /gene="rplB"
                     /locus_tag="IXT46_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAQ4946658.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            10391..10669
                     /gene="rpsS"
                     /locus_tag="IXT46_000723"
     CDS             10391..10669
                     /gene="rpsS"
                     /locus_tag="IXT46_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAQ4946659.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            10692..11039
                     /gene="rplV"
                     /locus_tag="IXT46_000724"
     CDS             10692..11039
                     /gene="rplV"
                     /locus_tag="IXT46_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAQ4946660.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            11053..11709
                     /gene="rpsC"
                     /locus_tag="IXT46_000725"
     CDS             11053..11709
                     /gene="rpsC"
                     /locus_tag="IXT46_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAQ4946661.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            11712..12146
                     /gene="rplP"
                     /locus_tag="IXT46_000726"
     CDS             11712..12146
                     /gene="rplP"
                     /locus_tag="IXT46_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAQ4946662.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            12136..12324
                     /gene="rpmC"
                     /locus_tag="IXT46_000727"
     CDS             12136..12324
                     /gene="rpmC"
                     /locus_tag="IXT46_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAQ4946663.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            12349..12615
                     /gene="rpsQ"
                     /locus_tag="IXT46_000728"
     CDS             12349..12615
                     /gene="rpsQ"
                     /locus_tag="IXT46_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAQ4946664.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            12673..13041
                     /gene="rplN"
                     /locus_tag="IXT46_000729"
     CDS             12673..13041
                     /gene="rplN"
                     /locus_tag="IXT46_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAQ4946665.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            13078..13386
                     /gene="rplX"
                     /locus_tag="IXT46_000730"
     CDS             13078..13386
                     /gene="rplX"
                     /locus_tag="IXT46_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAQ4946666.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            13414..13953
                     /gene="rplE"
                     /locus_tag="IXT46_000731"
     CDS             13414..13953
                     /gene="rplE"
                     /locus_tag="IXT46_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAQ4946667.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            13972..14157
                     /locus_tag="IXT46_000732"
     CDS             13972..14157
                     /locus_tag="IXT46_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAQ4946668.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            14193..14591
                     /gene="rpsH"
                     /locus_tag="IXT46_000733"
     CDS             14193..14591
                     /gene="rpsH"
                     /locus_tag="IXT46_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAQ4946669.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            14623..15159
                     /gene="rplF"
                     /locus_tag="IXT46_000734"
     CDS             14623..15159
                     /gene="rplF"
                     /locus_tag="IXT46_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAQ4946670.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            15320..15676
                     /gene="rplR"
                     /locus_tag="IXT46_000735"
     CDS             15320..15676
                     /gene="rplR"
                     /locus_tag="IXT46_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAQ4946671.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            15697..16197
                     /gene="rpsE"
                     /locus_tag="IXT46_000736"
     CDS             15697..16197
                     /gene="rpsE"
                     /locus_tag="IXT46_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAQ4946672.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            16212..16391
                     /gene="rpmD"
                     /locus_tag="IXT46_000737"
     CDS             16212..16391
                     /gene="rpmD"
                     /locus_tag="IXT46_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAQ4946673.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            16435..16875
                     /gene="rplO"
                     /locus_tag="IXT46_000738"
     CDS             16435..16875
                     /gene="rplO"
                     /locus_tag="IXT46_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAQ4946674.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            16875..18170
                     /gene="secY"
                     /locus_tag="IXT46_000739"
     CDS             16875..18170
                     /gene="secY"
                     /locus_tag="IXT46_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAQ4946675.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            18232..18879
                     /locus_tag="IXT46_000740"
     CDS             18232..18879
                     /locus_tag="IXT46_000740"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAQ4946676.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            19070..19288
                     /gene="infA"
                     /locus_tag="IXT46_000741"
     CDS             19070..19288
                     /gene="infA"
                     /locus_tag="IXT46_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAQ4946677.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            19321..19437
                     /gene="rpmJ"
                     /locus_tag="IXT46_000742"
     CDS             19321..19437
                     /gene="rpmJ"
                     /locus_tag="IXT46_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAQ4946678.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            19455..19820
                     /gene="rpsM"
                     /locus_tag="IXT46_000743"
     CDS             19455..19820
                     /gene="rpsM"
                     /locus_tag="IXT46_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAQ4946679.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            19848..20237
                     /gene="rpsK"
                     /locus_tag="IXT46_000744"
     CDS             19848..20237
                     /gene="rpsK"
                     /locus_tag="IXT46_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAQ4946680.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            20317..21255
                     /locus_tag="IXT46_000745"
     CDS             20317..21255
                     /locus_tag="IXT46_000745"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAQ4946681.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            21283..21663
                     /gene="rplQ"
                     /locus_tag="IXT46_000746"
     CDS             21283..21663
                     /gene="rplQ"
                     /locus_tag="IXT46_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAQ4946682.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            21935..22774
                     /locus_tag="IXT46_000747"
     CDS             21935..22774
                     /locus_tag="IXT46_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4946683.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            22750..23619
                     /locus_tag="IXT46_000748"
     CDS             22750..23619
                     /locus_tag="IXT46_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4946684.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            23609..24406
                     /locus_tag="IXT46_000749"
     CDS             23609..24406
                     /locus_tag="IXT46_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAQ4946685.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            24609..25355
                     /gene="truA"
                     /locus_tag="IXT46_000750"
     CDS             24609..25355
                     /gene="truA"
                     /locus_tag="IXT46_000750"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAQ4946686.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(25688..28357)
                     /locus_tag="IXT46_000751"
     CDS             complement(25688..28357)
                     /locus_tag="IXT46_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAQ4946687.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(28595..28783)
                     /locus_tag="IXT46_000752"
     CDS             complement(28595..28783)
                     /locus_tag="IXT46_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAQ4946688.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            29053..29415
                     /locus_tag="IXT46_000753"
     CDS             29053..29415
                     /locus_tag="IXT46_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4946689.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            29467..31149
                     /locus_tag="IXT46_000754"
     CDS             29467..31149
                     /locus_tag="IXT46_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAQ4946690.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            31266..33302
                     /gene="recG"
                     /locus_tag="IXT46_000755"
     CDS             31266..33302
                     /gene="recG"
                     /locus_tag="IXT46_000755"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAQ4946691.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            33351..34352
                     /gene="plsX"
                     /locus_tag="IXT46_000756"
     CDS             33351..34352
                     /gene="plsX"
                     /locus_tag="IXT46_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAQ4946692.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            34474..34716
                     /gene="acpP"
                     /locus_tag="IXT46_000757"
     CDS             34474..34716
                     /gene="acpP"
                     /locus_tag="IXT46_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAQ4946693.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            34984..35988
                     /locus_tag="IXT46_000758"
     CDS             34984..35988
                     /locus_tag="IXT46_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4946694.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            35989..36933
                     /locus_tag="IXT46_000759"
     CDS             35989..36933
                     /locus_tag="IXT46_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4946695.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            36933..37895
                     /locus_tag="IXT46_000760"
     CDS             36933..37895
                     /locus_tag="IXT46_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4946696.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            37922..38836
                     /locus_tag="IXT46_000761"
     CDS             37922..38836
                     /locus_tag="IXT46_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4946697.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            38862..40643
                     /locus_tag="IXT46_000762"
     CDS             38862..40643
                     /locus_tag="IXT46_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4946698.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            40991..41677
                     /locus_tag="IXT46_000763"
     CDS             40991..41677
                     /locus_tag="IXT46_000763"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAQ4946699.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            41697..45278
                     /gene="smc"
                     /locus_tag="IXT46_000764"
     CDS             41697..45278
                     /gene="smc"
                     /locus_tag="IXT46_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAQ4946700.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            45287..46096
                     /locus_tag="IXT46_000765"
     CDS             45287..46096
                     /locus_tag="IXT46_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4946701.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            46107..47105
                     /gene="ftsY"
                     /locus_tag="IXT46_000766"
     CDS             46107..47105
                     /gene="ftsY"
                     /locus_tag="IXT46_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAQ4946702.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            47292..49559
                     /gene="gshAB"
                     /locus_tag="IXT46_000767"
     CDS             47292..49559
                     /gene="gshAB"
                     /locus_tag="IXT46_000767"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAQ4946703.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(49648..50100)
                     /locus_tag="IXT46_000768"
     CDS             complement(49648..50100)
                     /locus_tag="IXT46_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAQ4946704.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            50250..51200
                     /locus_tag="IXT46_000769"
     CDS             50250..51200
                     /locus_tag="IXT46_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAQ4946705.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            51193..52152
                     /locus_tag="IXT46_000770"
     CDS             51193..52152
                     /locus_tag="IXT46_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAQ4946706.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            52149..52904
                     /locus_tag="IXT46_000771"
     CDS             52149..52904
                     /locus_tag="IXT46_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4946707.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            52927..53880
                     /locus_tag="IXT46_000772"
     CDS             52927..53880
                     /locus_tag="IXT46_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4946708.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
BASE COUNT        17803 a         9832 c        11685 g        14934 t
ORIGIN      
        1 agttggcagg agaaaaccgt ttatacgaaa aaagggactg tgacaaatcg tgtcacagtc
       61 ccttttttat agtgtttttt ataggtagta ttttttagca actgttaagt catcatttaa
      121 ttcataaaca agtggttgac ctgttggaat ttcaagatcc atgatgtctt cgtcagagat
      181 accttcgata tgtttagcta gggcgcgtaa tgagttacca tgtgcagcta ctaaaacagt
      241 tttgttgtct agtaatgctg gagcaatttc atcttgccag aatggcaaag cgcgttctaa
      301 tgtcactttc aagttttctc caccaggaat atcgcgtttg tctaacattg cgtaacgacg
      361 gtcatttgct gcagaacctt cgtcagtttc ttccattaat ggaggaagag tatcgtaaga
      421 acgacgccag atgtgcactt gttcgtcgcc gtatttttca gctgtttctt ttttgttcaa
      481 accttgtaat ttaccatagt gacgttcgtt taagcgccat gatttgattt gtggtaccca
      541 aagttgatct gaatattcta agatcaagtt acatgttttg attgcacgag ttaaaacaga
      601 agtgtaagca acatcaaatt cgattccagc ttctttgatt ttgcgtccgc cttcttttgc
      661 ttcttcgatt ccttctggtg ctagatttac atcagcccaa ccagtaaatt ggttcaatgc
      721 attccattca ctaagaccgt gacgagaaaa aactaatttt ggcatgttta gctctccttt
      781 taagataggt ttatatttct gaaattttca gttctgtttt attgtacaat tttttggaag
      841 agatttccat cgaaaaatta gataagattc tatgagaaaa caagtagaga atataaaaaa
      901 acgaacagtg cccacgcaac tgttcgtttt taggtattag atgcataatt gctcgatttc
      961 tttttcaggt aaattgatat atttataaca tgttccaact gaaacaccgc attttgaaga
     1021 aataaattgg atcgtttctt ttttttcata atagagacgt cggatttttt tgatcgtttt
     1081 tgcatcgatt tttggtcttc cgccgatttt tcctttttta cgagcttcat ctaatccaac
     1141 taatgtacgt tctttgatca atgcgcactc catgtttgct aggttttcca ttaattggaa
     1201 atagattttt cccatttcgc gcgtatcgat tccttcatca agactaatca agtgcagccc
     1261 gcgatctttg aataattgcg tgagttctgt taattgccgc gtagatttgc ctaatcgatg
     1321 aagttggcaa atgactagtg catcgccttg ttgcatgtca gcgatcactg actccaaatg
     1381 aacagcagta gaatcatttt gttccacttc atatgtctca tggaaaattt cttgacaacc
     1441 aaagtcagat aattgatcaa cctgagttgt taaatcaacg tcatttatgg ttgtgcgtgc
     1501 ataaccaata attttcatgg tgattccttt ctagcagtga ttttctaact ggatataaca
     1561 gtaaaaatgt agcataaagt acgtcaaaaa gatagttttt tcgcaaattt tccgctgtct
     1621 ttttttattg gatgatcaag cagtttttct ttatttacga cggattgcgt caagaatctc
     1681 aacgcctttt tctgagccga caactacttt agaaaccatg tttaggaaaa gcccatgttc
     1741 tactacccca acaagttcat ctaaataggt agctaagctt tctggctgtt cgatgacttc
     1801 tagatgcaga tcaatgatgt aatgaccacc atctgtggtt aagacttctc cgttttcgtc
     1861 tgtacgcaag acgggttgga atcttttttc ttcaaaaata tgaagtagct gttgggagcc
     1921 ataagggatc acttcaactg ggagtgggaa cttcccaagt ttatcgacta atttagaaga
     1981 atcaacgatc caaatcgttt cttttgagta cgtagcgact attttctcga aaagcaaagc
     2041 agcgccgccg cctttgatcc cttgaaaatc agcactgatt tcatcagcac cgtctattgt
     2101 caaatcgact acggggactt catcaatact ctttaacggt attcctaatt tttccgcttg
     2161 ttcttttgtc gcatttgaag tagtaactcc tgtgatacgt aaaccttctt cacgcatacg
     2221 gcgaccaatc tcttctacca tataataggc ggttgaaccg gtcccgagac ctacgatcat
     2281 cccgtccttt acgaatttcg cggcttcaat gccagctaat tgttttaaat tcatctttgc
     2341 gtccaccttt ttttagtttg agcatcgtgc tttcctcact attttagcgt gatttacggt
     2401 aaaaagatac cattcttttt tattccaata aagctttttc aaaaaaaatt gcatctcttg
     2461 ttgacatgtt ttttcattcg tgatattcta acaaaggtgc tttatctaca ggtttctgtg
     2521 aagaaacgtg ctgactgttt atcaaagcat atttgataag gatgcagaca ttgcatttat
     2581 tttttatcac aaaaaaagaa ccacctggat gtgtggaact agacgcaaat cgtgggaagg
     2641 aggaaacaag gaatgcctac aattaaccaa ttagtacgta aacctcgtaa atcaaaggtg
     2701 gaaaaatcta attcacctgc tttgaacaaa ggatataaca gctttaagaa aactcaaact
     2761 aacgtaaact cacctcaaaa acgtggggta gcaactcgtg tgggtacaat gacacctaaa
     2821 aaaccgaact cagctttacg taaatatgca cgtgttcgtt tgtcaaactt aattgaagtt
     2881 actgcttata tcccagggat tggtcataac ttacaagaac acagtgttgt attattacgc
     2941 ggtggtcgtg taaaagactt accaggggta cgttaccata tcgttcgcgg tgctttagat
     3001 actgctggtg ttaacgaccg taaacaaagc cgttctaaat acggaactaa aaaacctaaa
     3061 gcttaatttt aattattaaa caaatgaaac ttgcttctac tatatagaag taattactat
     3121 gaacaatatt tcggaaggag gagttacgga tgccacgtaa aggtcctgtt gcaaaacgtg
     3181 atgttttacc agatcctatt tataactcaa aattagtaac tcgcttgatc aaccgtgtaa
     3241 tggttgacgg aaaacgcggg attgcagcta acattatcta taatgccttt gacttgatca
     3301 aagaatctac aggtaacgat ccattagaag tgtttgaaca agcaatgaaa aacgttcaac
     3361 ctgttcttga agttaaagca cgtcgtgttg ggggttcaaa ctaccaagta ccagttgaag
     3421 ttcgccctga acgccgcgtt actctaggtc ttcgttgggt agtaaactac gctcgcttgc
     3481 gcggtgaaca cacaatggaa gaacgcttag caaaagaaat catggatgct gcaaacaaca
     3541 caggtgcttc tgttaaaaaa cgtgaagaca ctcataaaat ggctgatgcc aaccgtgcgt
     3601 ttgctcacta tcgctggtaa gattctctct gtttggtcgg cttttataag tcgacctcag
     3661 atagtgtcct tatttttagc aactagatag taaagagagg agaaacaagg agaatgacca
     3721 gagaattttc tttacaaaac actcgtaata tcggtatcat ggcccacatc gatgctggta
     3781 aaacgactgc tactgaacgt atcttgtact atactggtaa aatccataaa attggtgaaa
     3841 ctcatgaagg agcttcacaa atggactgga tggaacaaga acaagaacgt ggtattacga
     3901 tcacttctgc tgctactaca gcacaatgga agggtcaccg aatcaacatc atcgacacac
     3961 caggacacgt agacttcaca gttgaagttg aacgttcatt gcgtgtactt gatggtgctg
     4021 taactgttct tgatgcacaa tcaggtgttg aacctcaaac tgaaacagtt tggcgtcaag
     4081 caacaactta tggtgtacct cgtatcgtat ttgcaaacaa aatggacaag atcggtgctg
     4141 acttcttata ttcagtatca actttacatg accgtttgca agcaaacgct cacccaatcc
     4201 aattaccaat tggtgcggaa gacgacttca caggaattat cgaccttgta acaatgaagg
     4261 ctgaaatgta tacaaacgat cttggaacag agatcgaaga aacagaaatt cctgaagaat
     4321 accgcgaatt agctgaagaa tggcgcgaaa aattggttga agctgtagct gaaactgatg
     4381 aagaacttac tttgaaatac ttagaaggtg aagaaatcac tgaagctgag ttaaaagaag
     4441 gtatccgccg cgcaacagtt aacgtagaat tctacccagt actatgtggt tcagcattta
     4501 agaacaaagg ggttcaatta ctattggacg ctgttcttga ttacttgcca tcaccgttag
     4561 atatcccagc tatcaaaggg attgacccta aaactgatga agaagtagaa cgtcctgcag
     4621 acgacagcgc tcctttctca gctttagcat ttaaagttat gactgaccca ttcgtaggtc
     4681 gtttaacttt cttccgtgtg tactctggtg ttttacaatc aggttcatac gtacaaaacg
     4741 caacaaaagg caaacgtgaa cgtgttggtc gtatcctaca gatgcatgcc aactctcgtt
     4801 cagaaatctc tgaagtttac gctggagata tcgctgctgc tgttggtttg aaagacacaa
     4861 ctactgggga cacactatgt gatgaaaaga gtctagttat tcttgaatcc atggaattcc
     4921 cagaaccagt tatccaagtc gctattgaac ctaaatcaaa agctgaccaa gataaaatgg
     4981 gtgtggcttt acaaaaacta tctgaagaag atcctacttt ccgtgctgaa acaaacgtgg
     5041 aaacaggcga aacaatcatc gctggtatgg gtgaacttca cttagatatc atcgttgacc
     5101 gtatgcgtcg tgaattcaaa gttgaagcta acgtaggtgc gcctcaagta tcttaccgtg
     5161 aaactttccg tgctggcact caagccgaag gtaagtttgt acgtcagtct ggtggtaaag
     5221 gtcaatacgg tcacgtatgg attgaattta caccaaatga agaaggtgct ggtttcgaat
     5281 ttgaaaatgc gatcgtcggt ggggttgttc ctcgtgaata cattccagct gttgaaactg
     5341 gtttgaaaga tgctatggaa aatggtgtct tagctggcta tccattagta gatatcaaag
     5401 ctaaacttta cgatggttca taccatgatg tcgattcaaa tgaaactgcc ttccgtgttg
     5461 ctgcttctat ggcattacgt gcagcagcta agaaagctaa tccagtaatc cttgaaccaa
     5521 tcatggctgt agaagttgtt atccctgaag attatttagg tgatgttatg ggtcacgtaa
     5581 ctgctcgtcg tggacgtgtt gaaggtatgg aagctcgcgc tggcggccaa caagttgttc
     5641 gtgcgatggt tccacttgct gaaatgtttg gttatgctac aactcttcgt tctgctactc
     5701 aaggtcgtgg tacatttaca atgacatttg accactacga agatgtacca aaatcagtac
     5761 aagaagaaat cattaagaaa aacggcggaa aagctgaata atttcttaaa accggatagt
     5821 cctgcaaaga gattatccaa agagactata tttttaatat agtttcgtgt aaaataatta
     5881 tcgatgatat gggcatgtgg tgtaccttgt gtacatcata tacctatcag acaaataaaa
     5941 aatatattgt atttttagga ggacatttta aaatggcaaa agaaaaattt gaccgttcta
     6001 aaccacacgt taacattggt actatcggac acgttgacca tggtaaaact acattaacag
     6061 ctgcaatcac aactgtacta tctaagaaaa acggcggcca agctatggct tacgatcaaa
     6121 tcgatggtgc tccagaagaa cgcgaacgcg gaatcacaat ctcaacagct cacgttgagt
     6181 atgaaacaga tacacgccac tacgctcacg ttgactgccc aggacacgcg gattacgtta
     6241 aaaacatgat cactggtgct gctcaaatgg acggagctat cttggtagtt tctgctgctg
     6301 acggcccaat gcctcaaact cgtgaacaca tcctattgtc tcgtcaagtt ggtgttcctt
     6361 acatcgttgt attcttgaac aaagtagaca tggttgatga cgaagaatta ctagaattag
     6421 ttgaaatgga agttcgtgac ctattaacag aatacgaatt ccctggtgac gatgttcctg
     6481 tagttgctgg atcagctttg aaagctctag aaggcgacgc ttcatacgaa gaaaaaattc
     6541 ttgaattaat ggctgcagtt gacgaataca tcccaactcc agaacgtgac aacgacaaac
     6601 cattcatgat gccagttgaa gacgtgttct caattactgg acgtggtact gttgctacag
     6661 gtcgtgttga acgtggacaa gttcgcgttg gtgacgaagt tgaagttgtt ggtattgctg
     6721 aagaaacttc aaaaacaaca gttactggtg ttgaaatgtt ccgtaaattg ttagactacg
     6781 ctgaagctgg agacaacatt ggtgctttac tacgtggtgt tgcacgtgaa gacatccaac
     6841 gtggacaagt tttagctaaa ccaggtacaa tcacacctca tacaaaattc tctgcagaag
     6901 tatacgtgtt gacaaaagaa gaaggtggac gtcatactcc attcttcact aactaccgtc
     6961 cacaattcta cttccgtaca actgacgtaa caggtgttgt tgaattacca gaaggaactg
     7021 aaatggttat gcctggcgac aacgtaacaa tggaagttga attaatccac ccaatcgcta
     7081 tcgaaaacgg tactaaattc tcaatccgtg aaggcggacg tacagttggt gccggtgtcg
     7141 ttacagaaat caaagcttaa ttcacttaag ttttaaagta aagcaacatt tattcggacg
     7201 taatcgctcg gaacgaaggt cttaggatct ttgttccgag cttttttatt tattgcagga
     7261 tcaggaaaaa agacaggagt attataaata gaagaaacac gaaataaaag agtcagtatt
     7321 ttctaaatga aactttatga aaacaaaatg ttttttacaa gaaaaagcct tgctttgtga
     7381 gtttatatat attataatga caaaggtgcg tttactttag tgaattgcac agacgtaatc
     7441 agaatgattt cgtcggctaa gaaacgagag gttgcgacac gcccggacgc tttgccacga
     7501 acgagcgtga cggaaatttt cgtggagcta tgtctacttt tcaaaatagg cgaaggaggg
     7561 aacaagatgg caaaacaaaa aattcgtatc cgtttaaaag cgtatgaaca ccgtatttta
     7621 gatcaatcag cggataaaat cgtggaaact gcaaaaagaa ctggagctag cgtgtctggt
     7681 ccaattccat taccaactga acgcagtctt tacacaatca tccgtgcgac tcataaatac
     7741 aaagattcac gcgaacaatt cgaaatgcgt acacacaaac gtcttatcga cattgtgaac
     7801 ccaacaccaa aaactgttga tgctttgatg aagctagact taccatctgg tgtaaacatc
     7861 gaaatcaaat tataaaacta aaacaaaaat aatggaggtg tactcatgac caaaggaatc
     7921 ttagggaaaa aagtgggaat gacacaaatc ttcactgaat ctggtgaatt aattccagta
     7981 actgttgtag aagctactcc aaacgtagta ctacaagtga aaacaatgga aacggatggc
     8041 tacgaagcta ttcaagttgg ttaccaagat atgcgtgaag ttttatcaaa caaacctgcg
     8101 aaaggtcatg ttgcaaaagc aaacacggct cctaagcgct tcattcgtga attcaaaaat
     8161 gttgagctag gagaatatga agtaggaaaa gaaattacag tagatgtttt ccaagcagga
     8221 gacattattg atgtaacagg tactacgaaa ggtaaaggat tccaaggggt tatcaaacgc
     8281 cacggacaaa gccgcggacc aatggctcac ggttctcgtt accatcgtcg tcctgggtca
     8341 atgggtccag ttgcacctaa ccgtgtattt aaaaacaaac gtcttgctgg ccgtatgggt
     8401 ggcaaccgcg taactatcca aaacttggaa gttgtacgtg tcgatgcaga aagaaatgtt
     8461 atcttgatca aaggtaatgt tcctggagct aaaaaatctt taattactat caaatcagct
     8521 gtgaaagcta aataattgta ggaagaaagg aggaactaag gaatgccgaa tgtagcatta
     8581 ttcaaacaag atggaagcca aaacggtgaa atcacactta acgaagaaat cttcggaatt
     8641 gaacctaatg aaagtgttgt ttacgatgca atcgtaatgc aacgtgcgtc attaagacaa
     8701 ggaacacacg cggttaaaaa ccgtagcgct gttcgcggcg gcggacgtaa accatggcgt
     8761 caaaaaggaa caggtcgtgc acgtcaagga tctatccgct caccacaatg gcgtggaggt
     8821 ggcgtagtct ttggaccaac accacgttct tacagctaca aacttcctaa aaaagttcgt
     8881 cgtttagcaa tgaaatctgt attgtcagaa aaagttgctg aaaacaactt ggtagcaatc
     8941 gaaggcttga acttcgacgc accaaaaaca aaagaattca aacaagttct tgctaactta
     9001 tctatcgact ctaaagtatt ggttgttcta gaaaaaggta acgactttgc tgctttatca
     9061 gcacgtaact taccaaacgt ttctgtagta acttctgata atgtgagtgt gctagacgtt
     9121 gtatcaaata caaaagtgtt agcaacacaa actgctctta ctcaaattga ggaggtgctt
     9181 gcataatgaa cttactagac gtaatcaaac gcccagtgat cactgaaaaa tcaatgcttg
     9241 ccatggatga caagaaatac acttttgaag tggacactcg cgcaaacaaa actttagtaa
     9301 aacaagcggt agaagctgct tttgacgtta aagtcaaaaa cgtgaacatc gtgaacgtac
     9361 gtgcgaaatt caaacgtatg ggcaaatatg caggatatac aaaaaaacgt cgcaaagcga
     9421 tcgttacatt gactgaagat tcaaaagaaa tccaattatt cgaagctgct gaataagcac
     9481 taatagataa ctcattaaat taggagggaa aaacgtggcg attaaaaagt acaaacctac
     9541 ctcaaatggt cgtcgtaaca tgacaggttc tgattttgct gaaatcacaa catcaacacc
     9601 tgaaaaatca ttgttacaac cattgaaaaa ccatgctgga cgtaacaaca acggccgcat
     9661 cactgtacgt catcaaggtg gcggacacaa acgccaatat cgcgtgatcg acttcaaacg
     9721 taacaaagat aacgttgttg caactgttca aacgatcgaa tatgatccaa accgttcagc
     9781 taacatcgcg ttagtacact atgaagatgg agtgaaagct tacatcttag cacctaaagg
     9841 actagaagtg ggtatgaaac ttgtttcagg tccagaagca gatatcaaag tcggaaatgc
     9901 tcttccatta gaaaacattc cagttggtac tgttatccac aacattgaaa tgaaacctgg
     9961 taaaggtgga caattgatcc gttctgctgg tacaagtgct caagtacttg gtaaagaagg
    10021 caaatacgta ttgatccgct tgaactctgg tgaagttcgt atgatcttag ctgcatgccg
    10081 tgctacaatc ggttctgtag gtaacgaaca acacgaatta atcaacatcg gtaaagctgg
    10141 acgctctcgt tggatgcgta aacgcccaac tgtacgtggt agcgtaatga accctaatga
    10201 tcacccacac ggtggtggtg aaggtaaagc tcctatcgga cgtaaagcac cagtttctcc
    10261 ttggggtcaa ccagctcttg gttacaaaac tcgtaacaaa aaagctaaat cagacaaact
    10321 tattgttcgt cgtcgcaaaa ataaataatt actttgacca tgtgtcgcac attttgagag
    10381 gaggttcacc atgggtcgta gtttaaagaa aggacctttt gtcgatgagc atttaatgaa
    10441 aaaagttgaa gctcaagcag gggttgaaaa gaaaaaagtt atcaaaactt ggtcacgccg
    10501 ttcaacagtt ttcccaagtt ttgttggata taccatcgca gtttatgatg gacgtaaaca
    10561 tgtaccagtt tacatccaag aagacatggt aggacacaaa ttaggtgaat ttgcacctac
    10621 aagaacttat cgtggacatg ctgctgacga taagaaaacg aaacgctaat ttgaggggag
    10681 gataaatcca aatggcagaa caaatcacat cagctaaagc aactgcaaaa acagttcgca
    10741 cttcacctcg aaaagcccgt ttagtaattg accttatcag aggtaaaagt gtcgcagatg
    10801 caatttcaat cttgaaattc acaccaaaca aatctgctgg aatcattgaa aaagtattga
    10861 tgtcagcagt tgcgaatgca gaaaataact ttgacttaga tgttgaaaac ttggtagtaa
    10921 gcgaagcttt tgttaacgaa ggacctacaa tgaaacgttt ccgtcctcgt gcaaaaggat
    10981 cagcttctcc aatcaacaaa cgtacaagtc atatcacggt agtcgtatca gaaaaataag
    11041 gagggataat cagtgggtca aaaagtacat ccaattggaa tgcgtgtagg catcatccgc
    11101 gactgggatg ctaaatggta tgctgaaaaa gagtatgctg agttcttaca cgaagattta
    11161 agaatccgta aatttatttc aactaaactt gctgatgctg ctgtatcaac agttgaaatc
    11221 gaacgcgcaa caggtcgcgt aaacatttca attcacacag ctaaaccagg tatggttatt
    11281 ggtaaaggcg gttctgaagt cgaaagccta agaaaagaat taaacaaatt aactggtaaa
    11341 agaatccata tcaatatcgt ggaaatcaaa aaaccagatc tagatgcaaa attagtaggt
    11401 gaaggaatcg cacgtcaatt agaaaaccgt gttgctttcc gtcgcgctca aaaacaagcc
    11461 atccaacgct caatgcgtgc tggcgctcaa gggatcaaaa ctcaagtatc tggtcgtcta
    11521 aacggagcag atatcgctcg ttcagaagga tactcagaag gaactgttcc tcttcatact
    11581 ttacgtgcgg acattgatta cgcatgggaa gaagcagata caacatacgg aaaactagga
    11641 gttaaagtgt ggatctatcg tggagaaatt cttccaacta aaaaaaacac tgagaaagga
    11701 gggaaataat catgttagta cctaaacgtg taaaacaccg tcgtgaattc cgcggaaaaa
    11761 tgcgcgggga agctaaaggc ggaaaagaag tagcattcgg tgaatacggt ttgcaagctg
    11821 ttgattcaca ttggatcaca aaccgccaaa tcgaagctgc tcgtatcgca atgactcgtt
    11881 acatgaaacg tggtgggaaa gtatggatta aaattttccc tcacaaatct tatactgcca
    11941 aagcaattgg ggtacgtatg ggttctggta aaggggcacc tgaaggatgg gttgcaccag
    12001 taaaacgtgg taaaatcatg tttgaaatcg caggcgttcc tgaagaagta gctcgtgaag
    12061 cgttacgtct agcttctcac aaattaccaa tgaaaactaa gatcgtaaaa cgtgaggaaa
    12121 tgggtggtga atcgaatgaa ggttaaagaa atcagagaat taaccactgc cgaaatgctt
    12181 gatcaagaaa aacaattaaa agaagaattg tttaatctta gattccaatt agcaacaggt
    12241 caattagaaa acactgcacg tattaaagaa gtacgtaaat cgattgcacg catcaaaact
    12301 gtgttgcgtg aacaagctaa gtaattatgg aaggaggcca ttaagcgtat gactgaagga
    12361 agaaatcaac gcaaagttta tcaaggtcgc gtggtttcag acaaaatgga taaaacaatt
    12421 accgttgctg tcgaaacaaa gaaaaaccac cctatctatg gcaaacgcat gaactattct
    12481 aagaaataca aagtgcatga tgaaaacaac acagcaaaag ttggcgacat cgtgagaatt
    12541 atggaaactc gtccattatc agctacaaaa cgtttccgtt tgttggaagt agtcgaagaa
    12601 gcagttatta tctaataaca cgagattttc ctatatagat tgaatgcaaa atctgaaagg
    12661 aggatacaca acgtgatcca agcagaaagt cgtttaaaag tcgctgataa ctcaggcgca
    12721 cgtgaaattt tgacgatcaa agtccttggt ggatctggtc gtaaaactgc taacatcggt
    12781 gatgtgatcg ttgctacggt taaacaagca acgccaggtg gggttgtcaa aaaaggtgac
    12841 gtcgttaaag ccgttatcgt tcgaacaaaa tcaggagctc gtcgtacaga cggttcatat
    12901 attaaatttg atgaaaatgc tgcagtgatt attcgtgatg ataaaagccc tcgtggaaca
    12961 cgtatctttg ggccagttgc acgtgaacta cgtgaaaaca acttcatgaa gatcgtttca
    13021 ctagcaccag aagttttata atcttgagac acttatcaaa ggaggtgcga aacagttatg
    13081 tttgttaaaa aaggcgataa agttaaagtt atcactggaa aagacaaaaa caaagaaggc
    13141 gttgtactag cagcgttccc gaaaaaagat aaagttattg tcgaaggtgt aaatgtcgtt
    13201 aaaaaacacc aaaaaccttc tcaagctgct cctcaaggtg gaattgttga gatggaagcg
    13261 ccaattcatg tttctaacgt gatggtggtt gactctactg gtgtagctgg ccgagttggc
    13321 tacaaagaag tagacggcaa aaaagtccgt gtttctaaaa aaaccggtga agttttagat
    13381 aaataaaagt ttaaggaagg agggtcttac tgaatgaacc gcctaaaaga aaaatatctt
    13441 aaagaagtaa ctccatcatt gatggaaaaa tttaactata gctctgttat gcaaacacct
    13501 aaagttgaaa aaatcgtcat caacatgggt gttggtgatg cggtatcaaa cgctaaaaac
    13561 ttagataaag cagttgaaga attaactttg atcactggtc aaaaaccaat gattacaaaa
    13621 gctaaaaaat caatcgctgg attccgttta cgtgaaggaa tgccaattgg tgcaaaagtt
    13681 acattgcgcg gagaaagaat gtacgaattc ttagacaaat tggtttctgt ttcactacca
    13741 cgtgtacgtg acttccatgg tgtaagtaaa aaagcctttg acggtcgtgg aaactatact
    13801 ttaggtatta aagaacaatt gatcttccca gaagtagatt atgatttagt agataaagta
    13861 cgtggtatgg acatcgttat tgtaacaaca gcaaactctg atgaagaatc tcgtgagttg
    13921 ttgacacaat taggcatgcc attccaaaaa taattaaagg aggcgaacta cgtggctaaa
    13981 aaatcaatga ttgctaaaaa caaacgtcct gcaaaatttt caacacaagc ttatactcgt
    14041 tgcgaacgtt gcggacgtcc acattcagtt tatcgtaagt tccatctttg ccgtatttgc
    14101 ttccgcgaac ttgcctataa aggtcaaatt cccggcgtga agaaagctag ctggtaaaaa
    14161 gtaaattcgc ataagaagga ggtaaaagat caatggtcat gacagatcca attgcagatt
    14221 ttctaactcg tatccgtaac gcaaacatgg ttaaacatga gtctttagaa gtacctgcat
    14281 caaaaattaa acgtgacatc gctgaaatct tgaaacgtga aggtttcgtt cgtgatgttg
    14341 aatacatcga agatgacaaa caaggcgtga tccgtgtttt cctaaaattt ggtaaaaacg
    14401 gcgaacgtgt tatcacaaac ttaaaacgta tctctaaacc aggtttgcgt gcttatgtca
    14461 aagctgacga agtaccaaaa gtattgaacg gtttaggtat cgcaatcatt tcgacttctg
    14521 aaggtgttgt cactgataaa gaagctcgtg aaaaaaatat cggcggcgaa gttatcgctt
    14581 acgtatggta atcaagtaga atctacaagg aggtgtcttt aagtgagccg tatcggaaat
    14641 aaagtcgttg ttatccctga aggagtaaca gttactcaag acggaaacaa cgttacagtt
    14701 aaaggaccaa aaggtgaatt gactcgtact ttttcagcag atatcaaaat gaatatcgaa
    14761 ggaaacgaag taactttcac tcgtccaaac gacagtaaag aaatgaaaac aattcatgga
    14821 acaactcgtg cgaacttcaa caacatggtt gtaggtgtca gcgaaggttt ccaaaaagcg
    14881 ttagaactaa tcggggttgg gtaccgtgca caattacaag gatcaaaact tgtattgaac
    14941 gttggttact cacatccagt agaaatcaca ccaccagctg gagtaactgt tgaagtacca
    15001 gctaacacac aagtaattgt taaaggtgcg aacaaagaag aagttggcga attagctgca
    15061 aacattcgtg gaactcgtcc tccagaacct tataaaggta aaggtattcg ttatgttggc
    15121 gaatatgtac gccgtaaaga aggtaaaact ggtaaataat cgtttagaaa aattgcatag
    15181 aagccagcag caggaaaaag gcatttggct gaagtttacc ttcaaaaaaa tacattttta
    15241 cttgtgccgc agcttctatt tttcgaaacg tatttactgc ttgaaatagt agtacaataa
    15301 aaataaagag gtgacaattg tgattacaaa accagataag aacaaaacac gtcaaaagag
    15361 acatcgtcgt gtacgtaaca atatctctgg tactgctgag cgcccacgct tgaacgtttt
    15421 tcgttctaac aaaaacatct acgctcaaat tattgatgac gtagcgggtg taacgctagc
    15481 aagtgcctct accttggata aagaaatttc aggtggaaca aaaacagaag cagcacaagc
    15541 tgtcggtaaa ctagttgctg aacgtgcagc tgaaaaaggc attaaagtag tagtctttga
    15601 ccgtggtgga tacctttacc atggccgtgt gcaagcttta gctgaagctg ctcgcgaaaa
    15661 tggactagaa ttttagaaga aggaggaata ccattcatgg tttatatcga tccaaaacat
    15721 ttggaattag aagaccgcgt tgttgcaatt aaccgtgtaa caaaagttgt taaaggtgga
    15781 cgtcgtctac gttttgctgc tttagttgtt gtcggtgaca aaaacggaca cgtagggttt
    15841 ggtacaggta aagctcaaga agttcctgaa gcaatccgta aagcaattga agatgcgaag
    15901 aaaaacttag ttgaagtacc tatggttggt tcaacaatcc cacacgaagt aatcggtgct
    15961 tttagtggtg gtagaatcct aatgaaacct gctgtagaag gttctggggt tgctgctggt
    16021 ggaccagttc gtgccgtatt agaattagct ggggtagcag atatcacttc taaatcttta
    16081 ggctcaaata caccaatcaa cgttgttcgc gcaacagttg aaggtttgaa acaattgaaa
    16141 cgtgcagaag aagttgcaga acttcgcggc aaatcagttg aagaattaat cggataagga
    16201 ggacaacaat aatggctgaa ttaaaagtta ctttaaaacg cagtattatc ggacgtcctc
    16261 aaaaccaacg cgatacagtt aaagcgttag gtcttacaaa gattaacagt tcagtggtta
    16321 agccttctaa tgaagcaatt aaaggcatga tcaatactgt ttctcaccta gtggacgttg
    16381 aagaaattta atttagaaaa atcataacta gaacattaag gaggtgccaa acctatgaaa
    16441 cttcatgaat taaaacctgc tgaaggttca cgccaagtac gtaaccgtgt tggtcgtggt
    16501 acttcatctg gtaacggaaa aactgccgga cgcggacaaa aaggacaaaa agctcgttca
    16561 ggcggcggtg tgcgtttagg atttgaaggg ggacaaacac cattgttccg tcgtttacca
    16621 aaacgaggat tcacaaacgt gaaccgtaaa gactatgcag tcattaatct tgatgtattg
    16681 aaccgctttg aagacggagc tgaagtaact cctgttgctt tagttgaagc tggaatcgtg
    16741 aaaaacgaaa aagctggaat caaagtatta gctaatgggg aactaaacaa gaaattaact
    16801 gtgaaagcag caaaattctc taaagcagct caagaagcaa ttgaagcggc tggtggatca
    16861 atcgaggtga tctaatgttt agactattaa aagatgcttt taaagtaaaa gacattagat
    16921 cgaaaatcct atttactgta tttgtgttgt ttgtatttcg cctaggtgca catattactg
    16981 taccaggcgt aaatgctgct tcattgcaaa acctttcttc tttgccattt ttcaacatgt
    17041 tgaacttggt aagtggtagt gcgatgcaaa acttttccat tttctcaatg ggggtttcac
    17101 catacattac tgcttctatc gtcattcagc ttcttcaaat ggacatcgtg cctcgatttg
    17161 ttgaatggtc gaaacaaggg gaagttggtc gtaaaaaact gaatcaagcg actcgatatc
    17221 tgacattagt attggcattt atccaatctg tcggtatcac tgctggattc aatcaatacg
    17281 ctcaattagg tttcgtgaat aatcctaacg tagcaactta cgtaacgatc ggtttgattc
    17341 taacagccgg tacgatgttt gttacttggc taggagaaca gatcacagaa aaaggtatcg
    17401 gaaatggcgt atcaatgatc atttttgcag gtatcatttc tagattgcct gaaagtatca
    17461 gagaaattta tgaagattac tttataaata ttgatccttc agacatatgg aaatctgcta
    17521 tttttgtggc cattttacta gtagcggtct tgttgatcgt gacattcgta acatttttcc
    17581 aacaagctga acgcaagatc ccgatccaat atacgaaacg cgtagctggc gcgcctacaa
    17641 gcagctatct gccgttgaaa gtaaatgcag ctggagttat tccagttatc tttgctagtt
    17701 cgtttattgc tacgccaaat gctgttttac aagcattgag cggtagattc ggttctgaaa
    17761 actggtacaa agtgatgatg gagatcttta actataatac agcacctggt gctacgattt
    17821 atacgattct gatcgttgcc ttcactttct tctacgcctt tgttcaagta aaccctgaga
    17881 aattagcgga aaacttgcaa aagcaaggaa gttatatacc aagcgtacgc cctggtaagg
    17941 ggactgaaga gtatgtctca agattactga tgcgtttaag tacagttggt gcagtcttcc
    18001 ttggtttagt ggcattgctt ccaatcattg ctcaaatggt ttgggatctt ccacaatcaa
    18061 tcggattagg cggtacaagc ttactgatcg ttatcggtgt agctttagaa actgcgaaac
    18121 agttagaagg cttaatgctg aaacgtaaat atgttggatt cattgagtaa gaaagcgtgt
    18181 tgaggtttcc cctcaacaca cgttctcaca catttattag gagggaaaac aatgaacctc
    18241 attttaatgg ggctgccagg cgcaggtaaa ggaacacaag ctgaaaaaat cattgatgct
    18301 tatggtattc cgcacatctc aacaggagat atgttccgcg cagcgatgca aaacgaaaca
    18361 gctcttggcc tggaagcaaa gtcttatatg gataaaggtg cattagttcc tgatgaagta
    18421 acaaatggaa tcgtgaaaga gcgactagct gaaccagata cagagaaagg cttcttatta
    18481 gatggctttc cacgtacgct agatcaagca aaagctctgg acgcaatgct aaaagatttg
    18541 aataaaaaaa ttgatgctgt catcgatatc catgttggtg aagaaatctt ggtcgaacgt
    18601 ctagccggcc gatttatctg cagcaattgt ggagcaactt accataaaat tttcaaccct
    18661 acaaaagttg aagacacatg tgatcgttgc ggtgggcatg aattctatca aagagaagat
    18721 gataaacctg agacggttaa aaatcgtctg gctatcaaca tcaaaaatag tgaaccaatc
    18781 ttggcttatt ataaagaaca aggtttgcta aacactattg atggtgctcg tgaaatcgat
    18841 gctgtatttg cagatgtaca aaaaatcatt gaaaaatagc acgattgccc gtagccgact
    18901 tgcattatgc agttactctt gtcaagttca ataaattatg atagaatatg tcagtccgac
    18961 ttctagagaa tcctctagat gatccatttt gagaattttg aggtgggaac tgcagtttcc
    19021 gccattttat cgtgtgaaaa tgcgaaacaa gtacaaggag gtactgtgcg tggcaaaaga
    19081 agatatgatt gaagtcgaag gtacagtcgt cgaaactttg ccgaatgcaa tgtttaaagt
    19141 tgaactagaa aacggacacc aagttcttgc tactgtttca ggtaaaattc gtatgcatta
    19201 catccgtatc ttacctggtg acaaagtaac ggttgaattg tctccatacg atcttaaccg
    19261 tggccgtatt acttatcgct ttaaataatt gtactccgta aaactacagg aggtattatc
    19321 atgaaagtaa gaccatcagt aaaaccaatg tgcgaacatt gtaaagtaat tcgtcgtaaa
    19381 ggacgcgtta tggtgatttg cccagcaaat ccaaaacata aacaacgtca aggataattg
    19441 gaggtgctat aaatatggct cgtattgcag gagtagatat tcctcgtgat aaacgtgtag
    19501 tagtttcact tacttatatc tatggtattg gtaacactac tgctaaaaag atcttagctg
    19561 atgctggtgt atctgaagat gttcgcgttc gtgaattaac gaatgaacaa acagatgcta
    19621 tccgtgcaga agtagataaa ttaaaagttg aaggggatct tcgtcgtgaa gtgaacttga
    19681 acatcaaacg tttgatggaa atcggttctt accgtggaat ccgtcatcgc cgtggattgc
    19741 ctgttcgtgg acaaaacacg aaaaacaatg cacgtactcg taaaggccca gctcgcgcta
    19801 tcgctggcaa gaaaaaataa ttcttaagtg aaggaggtta aaacttcatg gcagcaaaaa
    19861 aagtgaatcg taaacgccgt gtgaagaaga atatagaagc aggtattgca catatccatt
    19921 ctacattcaa taacactatc atcatgatca ctgatactca cggaaatgca ttagcgtggt
    19981 catcagctgg ttcattaggt ttcaaaggaa gcaaaaaatc aactcctttt gccgctcaaa
    20041 tggcagcaga aactgctaca aaagcagcaa tggaacacgg attaaagact gttgaagtaa
    20101 cagttaaagg acctggttct ggacgtgaag cagcaattcg ttcattacaa gctacaggtt
    20161 tagaagtgac tgcaattcgt gacgtgactc cagttcctca taatggtgcc cgccctccaa
    20221 aacgccgtcg tgtttaatga gtgccgctca ttttgagttt tatcagtaac gtcattgaac
    20281 aagacacttt tcgttttgaa aggggtaaag ataagaatga ttgagttcga aaaaccaaga
    20341 atcgcaaaaa ttgatgaaga aaaagattat ggcaagttca tcgttgaacc tcttgaaaga
    20401 gggtatggga ctactttagg gaattcccta cgtcgtattt tattatcttc tttgccaggt
    20461 gctgccatca ctaatattca aatcgatggt gtactgcatg aattctctac catcaaaggt
    20521 gttagagaag acgtcactca aatcatcttg aacattaaag gcttagcgct gaaaatgtat
    20581 ggccaagaag aaaaaaccct tgaaatcgat attaccggac ctgctacagt aactgctggc
    20641 gatattatcg ttgatagtga tgtagaaatt cttaacaaag atatgtacat ctgtagtgtc
    20701 tctgaaggag ctacgttcca tgctcgctta acagtgaaac ctggacgtgg ttatgttcaa
    20761 gcagatgaaa ataaaaaaga agatatgcca attggcgttc ttccagtcga ttcaatctac
    20821 acacctgttc gtcgtgtgaa ctatcaagtt gagaacacac gtgttggaca ccgtgaagat
    20881 tttgataaat tgacgatgga gatttggaca gatggttcaa ttgaaccgtt ggaagcaatg
    20941 agtttgtctg cgaaaatcat gactgaacat ttggatattt ttgtgaactt aactgatgaa
    21001 gcaaaaaatg ctgaaatcat ggtcgaaaaa gaagaaacac aaaaagaaaa aatgttggaa
    21061 atgacgatcg aagagttaga cttgtctgtt cgctcttaca attgtttgaa acgtgcagga
    21121 atcaatactg tacaagaact tacaaataaa tctgagcctg aaatgatcaa agtccgtaac
    21181 ttaggacgta aatcattaga agaagttaaa gcaaaattgc acgacttagg tttaggttta
    21241 cgtaaagaag attaaaacct tttacgaagg agggaaacca acgtgagtta tcgtaaacta
    21301 ggacgcacat ctagccaacg taaagcgatg ttgcgtgatt taacaactga tttattaatc
    21361 aacgaacgta ttgtgactac tgaagctcgt gcgaaagaag ttcgctcaac tgcagaaaaa
    21421 atgatcactt taggtaaacg cggagatttg catgcacgtc gtcaagctgc ggctttcgta
    21481 cgtaatgaag ttgccagcgt gcgtgaagaa aatgaggaca tcgtcattga atcagcttta
    21541 caaaaactgt tcaacgatat tgcacctcgt tacgcagaac gtcaaggcgg atacacacgc
    21601 attttgaaga cagaaccaag acgcggtgat ggtgcaccaa tggttgtctt agaacttgtc
    21661 taaaatcaca ctaataacat cactttatag atgattcttt tagagtgtta tgatgttgga
    21721 agatattttt ccgagtctag ctcagcgctg ctcctcaagc gaatatcgct tggggagtaa
    21781 gcactcatca taaagtgttt ttttatacct tcaattacct gtcatgacag atatgtttga
    21841 aggcataaaa aaacatttta agcgagaaat aattgaaaat tttgtctttt tttgatagtg
    21901 ttagtaggaa ctttaggatg aagaaggagt aatcatggag ccaattattg aattagaaaa
    21961 gataaattat aaataccagc cagatgatct tcgccccgca ttgaaagatg tctcctttac
    22021 aattgataaa ggtgagtgga tcgctattat tggacacaat ggttcaggaa aatcgacact
    22081 tgccaaaacg atcaatggat tgcttctgcc agaatcaggg atcgtgaaag tgggaaatca
    22141 aatattggat gaagaaaata tttggacgat ccgacagatg gttggaatga tttttcaaaa
    22201 tccagacaat cagtttgttg gttcgacagt agaagatgac gttgcttttg gtcttgaaaa
    22261 tcaagggatt cccagagaag aaatgctagt gcgtgtgaaa gatgcacttg agaaagttag
    22321 aatggctgag tttgcttcac gcgagcctgc tcgtttatca ggagggcaaa aacaacgtgt
    22381 tgccattgcc ggcgtggttg ccttacgacc tgatatcatt attttagatg aagcaaccag
    22441 tatgctagat ccagaaggtc gtgaagaagt gatctctacg atcaagaaga tcaaagaaga
    22501 aagtcaattg accgttatat ctatcactca tgatattgat gaagcagcta atgccaatcg
    22561 gatactagtg atgagacaag gcgaacttgt ccgtgaaggt acaccaaaag aaattttttc
    22621 tgctggtcct gaactgatcg acttaggtct agatctacca tttcctgaaa aactgaagag
    22681 cgcactgaaa gaacgtgggg ttgatgtgcc cagtgaatat atgacagaag aaaggatggt
    22741 ggattggtta tggacatccg ttttgaacaa gtagacttca cttatcagcc gaatacacca
    22801 tttgaacaaa gagccttatt tgacatcaat atgacgatca aagaaaacag ttatactgca
    22861 ttagtagggc ataccggaag cgggaaatca accttacttc agcatttgaa tgcgcttgtt
    22921 aagccaacaa gcggtacagt ccatattgga gaacgagata ttcagccgga tacggataat
    22981 aagaatttaa agcccatccg aaaaaaagtt ggcatcgtct ttcagtttcc agaagcacag
    23041 ctattcgaag aaacggtagc aaaagacatt gctttcggtc ctaaaaactt tggtgtcagc
    23101 gaagaagaag cactagtcct agcaaaagaa acattagaac aagttgggct ggatgaaagc
    23161 tatttggaac gttcgccatt tgaactttca ggagggcaaa tgcgtagagt agcaatcgct
    23221 ggtgtgcttg ccatgaggcc ggaagtactt gtattggatg aaccaacggc aggacttgat
    23281 ccccagggca gaaaagaaat gatggagatg ttttggcgtc ttcataagga acagcagatc
    23341 actattgtat tagttacgca tttaatggat gatgtagcca attttgcaga ttatgtctat
    23401 gtgttggaaa agggacgaat cgttaatagc ggggagccgc aagaggtctt tcaaaacatt
    23461 gaatggctaa aagaaaaaca actaggcgta cctactgcca ccgagtttgc agaagaatta
    23521 atggctaaag ggatgaactt tgctaccttg cctttgacag ctgaagaatt agcagacgct
    23581 atcgtccatt atgctggagg aaatgcccat gatgaataaa ttgatatttg gtcgttatat
    23641 gcctggagat tccttgatcc atcgattgga tccccgagct aaattattag ccagttttta
    23701 ttttatcgga atcatttttt tagcaaataa ttgggaaacg taccttttgt tggcattttt
    23761 cacattactt tctgtcttct tgtcaaaagt agatttgaaa ttttttatcc gaggcattcg
    23821 cccattgatc tggctaatcc tcttcactgt agctttgcag gtcttgttta caagtggcgg
    23881 agaaacttat tggagttggg gtgttttcca tatcactgaa tttggtgtga tgaacggcct
    23941 ctttattttc tgtcgattcg tgttgatcat ttttatgtcg actctactca cgcttactac
    24001 accgcctttg gaattatcgg atgcgattga gtacttgctt cgtccattga aagccgtacg
    24061 gttcccagtc cacgaaattt cattgatgct gtcgattgct cttcgttttg tgcctacatt
    24121 gatggacgaa acagaaaaga tcatgaacgc tcagcgcgct cgcggtgttg attttggtga
    24181 aggaaaccta gttcagaaaa tgaaagcagt cattcctttg ctgattcctt tatttgtcag
    24241 cagcttcaac cgtgcggaag atcttgcgac tgctatggaa gcaagaggct acaaaggtgg
    24301 ggaaggaaga acgaaatatc gtgtattgca ttggcataat agagacacga tggttatcat
    24361 tgcttttgta ttattaactg tgctactgat ctttttaaga ggataaacgt tcagtgggcc
    24421 gctatctatt cttttcttgc tgatctgttt gcaagaaagg atgcaagcag tgtatgacaa
    24481 gaaatattag ggtctgtggc agactaaggt cacaggcctc tttcttttat ctgaaaagaa
    24541 agaacgaaaa aattttatag aaaaatcatt attccagata accttttagg aacaaaggag
    24601 agaaaaacat ggtacgttac aaagcaatca ttgcgtacga cggaacaaat tttaatggat
    24661 tccaaaaaca gccaaatggg cgtactgttc aagaagaagt agaaaaaaca ttacaaaaaa
    24721 tggcaaatgg aaaagaaatc acggtctttg gttcgggaag gacagatgcc ggagtacatg
    24781 cgatcgggca agtaatccat tttgattatc cagaggagcg tccgttagaa cgaatgcgtt
    24841 tcgcgctaga tacccagtca ccagaggata ttgctgtaag acaagtagaa attgtttcag
    24901 aagacttcca cgcaagatat ttggtcaaag aaaagacgta tcaatttcga gtggatatag
    24961 ggaaaccacg cagtcctttt cgacgccatt atgcaagtta ttttccttac ccacttgatt
    25021 tggaaaaaat tcagcgggcg cttcctgatt tattagggac tcacgatttc acctcttttt
    25081 gtgcatcagg aagctcgata gaggataaaa tacgtacgat ctacgaggct aagatggagg
    25141 taaatgaaac aaaagacgaa ttgttgttta catttagggg aaatggcttc ttgtataaga
    25201 tgatacggat cttagtagga acgcttttga aaattggcaa tggccgattg cctgaagata
    25261 gtatcccaga tattattgcg aaaaaagatc gtaatgcagc aggacctaca gcacaccctg
    25321 aaggacttta tttgtatgaa gtgaaatatg aataagaggt tatgatagaa gtggtcagct
    25381 tcaagaaata agaaggtatt tacgaaaatt acttctcaaa attttgcaaa atttcggctt
    25441 attttcgaag aagctacttc tggaacaccg tttaagaaag aggtcgtgag cctgtcattt
    25501 aactctgagt cacaaagagc aatttcaaaa aacagcttct catctttgat gaatatcgtg
    25561 acttgtggac gaggcgttga taagtgaatc atctttttgt tacctatttt ttctgtaacc
    25621 aaaaaacgat ggaacgttgt tttgattgcc cttggtgcgg acagtctgaa caggttccat
    25681 cgtttcttta ttttctacgt cttcttctgt gtgtgtttcg tggttgttct tctattgctg
    25741 gatcaatcgt gccataaaag gggcgattgc ggtcaaggta ccagacataa agaataaaca
    25801 atgcaataca taggacaaaa aggattgcac ctatcgtaaa tccttcaggc aagtaactga
    25861 aagtgacagt atgtttacct gctggaactt ttatcatcaa gaatgcgtct ttgaaattgc
    25921 tgaccttgac tggtttccca tcaattttag ctttccatcc tttgtcataa ggaatagttg
    25981 tcaccaacat ggaatcttca gcggtattta cagtcccaga agcttttctg ccagtggctt
    26041 ccatttcgac acctttttct ttgatctgat tcattgcggc ttgataggct acaacatcta
    26101 gaccaacgac tttaggctcc atgaaactta tttctttcgt cccataaaaa cttgcagtaa
    26161 atgtcactgt tgtctcttga ggataatagc caagatcata gtattgacca gaaatgttga
    26221 tttgcgtttt tcgcgatgta ccattgacag tgatcgtcgc actagaactt tctaattgcg
    26281 caaaattggt tgggaacaaa cttaagtaag cttgtgtatt tgcaggcaca tggacttccc
    26341 aagtgagctc ttttggctgg ttatctgctg tttctgagta agtgacgcca gtcgttgtct
    26401 ttgtgatcgt cgtattcaac tgattcttca aagtaggtgt atagaatgta aaatactgtt
    26461 catttagacc agacaatgta ttgatcaagt ttgtctgact ggtcaaatta tctgtcactg
    26521 gctgctcaac atcattaacg gacaacggtg cagtaaatgc tagtggcaat gcattgacat
    26581 tctgatacag tgtatagtcg ccgctttgac cagcttggcg gaagccatat ttactgaacg
    26641 tgctttcgtt tttagaaatg ttatatttga ttcctgtaaa cccatccatc agcaaagtat
    26701 tattgttata acggatattc aaatttgtcc ctcttgaacg gaaacctaat ttatccaggt
    26761 aagaggaaga attacgattt cttatagaag aaaacaaact gataccactg taaccatagt
    26821 tgatcgaatc gtttgcagat actggatcca gattttccaa gcggtaaaac gagtcggaat
    26881 ctttttttgt ttcatttaca agagctttca agtcaggata aggatcagta tataaactgc
    26941 gggaagcata attccaatca tcaagaatgc catggatcat actgttcgta ttgaccagtg
    27001 cttcagcaga catgatcaat aataacaata tactcagatg attgaatgaa agttttttat
    27061 gctgataaaa tcccacagca aaagcataaa tccctaagaa aaccactgtc aatacaaagg
    27121 aagtcatcgt cacataggtg tagcttcctt caggtttgat gccccatgcc accgcaaaga
    27181 gagcagctac gaccaaaatg attcctaaca acagcccacc atcgtcttgt tctatctttt
    27241 cccatccttt tcctgcaagc aggagcacta agaaagagaa cagataggca taacggaata
    27301 aaaacatatt cggtgcatgc ataccatgcc agaacaaatt caatggaaca agataaaaac
    27361 ttgcgataag tatggcgaaa agactgccgt acaaaaattt atttttcaac ggtactttcc
    27421 gactggcaaa ataaaacaga cagaggacta atggtagcag acctgcgtaa acgaacggaa
    27481 tcgatccgta ttttgtcgtg tcataaacac caatcatatt tttcatgatt agatccagat
    27541 aagaagtcgc ttctgttttc aacgtagtga tctgactcag tgcctcgcca tttgaccgaa
    27601 gatccagcac tgctggcaat acaatgatca ttgaagcgcc gcctgccagt aaagaagtga
    27661 taccataagg aacaatcgtt tttttatatt ctgaccagtt tgtcaataga cgggcgataa
    27721 aatataagaa agaaaatacg ccaatcataa aacccatata aaaactggat aaaaacaaga
    27781 gtaaataact gataaataaa agtttcggcc gtttaagatc cataacacga tgaatcccca
    27841 aaatcactaa tggaagataa acaaatgcat ccagccacat gatgatctcc gaatgtgcag
    27901 tgataaatga gatcaatgcg taactgacgc taagtgcaac atgcccccag cgaggaatct
    27961 tgaacgtacg tgcaagaaac caaaaagcca atccggcaca gccgacctta agcaaagtca
    28021 gaacatacag tgcatctggc atcatctggt ttggaaaaaa gaacaccagt ggcgtgaaga
    28081 tcccgcctag atagtaagaa attaaagata aataattcaa tcctagagaa gcattccatg
    28141 tataaaaaat actttgcttt ccaagaagaa catttcggaa gctggcatga aaattagaaa
    28201 actgtgaaaa ggcatcactt gccaaaatac ttctgctgct tccaggatag attccgatac
    28261 ttagataaac aagtgctaaa atcaaaaacg gaatcaggaa actagctgct gcgtagcgtc
    28321 cgttttctct aaagaatgac tttaaatttt ttttcatatt tattttccac caaatttcta
    28381 tgaagttgta ttcagtttat catatccttg tttttctctg cttaaaaaga gtctagtttt
    28441 cacaaaaaaa taaaatttag aataaataac ttcataattt gttcgtataa caaaaataaa
    28501 cgcaaaaaaa gggtaggaat caaaagtccc acccttaaaa atttttatta aataaaaaac
    28561 cgttcactat ctgaacggtc caagtatcat tcaattaaac gcgttcaact tttcctgatt
    28621 tcaaagcacg agttgacacc caaacttttt taggttttcc gtcgaccata acgcgaactt
    28681 tttgtaagtt aggtttaaca gtacgttttg ttgagttcat agcgtgtgaa cggttgtttc
    28741 cactttttgt cttgcgacct gtaaagtaac aaacttttgc catggtaatt tcctcctttg
    28801 ccttgatttg gagcaataga ataattcagc tcataccaga ctaacatatc atatagaatg
    28861 ggaatttgca agtacatttt catagataca attgacaatt gagaagaata attgtaaatt
    28921 aaacaaggtt atacctgaaa ttttgcaagg tttttgagta ctttgggtaa ctgcctttta
    28981 tttcaagttg cgctatgata aaatatgata gaagaaaaat gggagttttt tacccgttaa
    29041 ggaggctcat tcatggctgt aaaaattcaa acgtcagctg gaaccattga aattaccaat
    29101 gatgtaattg caacagttgt tggtggcgcc gcgacagatg tgttcggtgt tgtaggaatg
    29161 gccagcaaaa atcaaattaa agataatatt actgagattt tgcgtaaaga aaattactca
    29221 agaggagtag ttgtccgcca agaagataat ggtattgctg tagatgttta tacgattatc
    29281 agctatggta cgaaaatctc tgaagtttcc cgcaacgtcc aagaaaaagt gaaatacaat
    29341 ctagaggcat tattaggcgt aactgccaat tcagttaatg tctttgtaca aggtgttcgt
    29401 gtactgccag actaggcagg agactggctg gtaactcagc agtcgatctg aaggaggatt
    29461 atctaggtga gtgtaacaga aataagtgca agccagttcc aggaaatggt ccaggcaggt
    29521 gcgaatcgtc tgcaagtaaa tgcagaatac gtcaattcat taaatgtatt ccctgtgcca
    29581 gatggcgata cgggaacaaa tatgaatcta tctatgacta gtggagctaa ggcagtagta
    29641 gattcaacct cagaaaaagt aggagaatta gcagcaatgc tttcaaaagg attgctgatg
    29701 ggtgcgcgcg gaaattccgg cgttattttg tctcaattgt ttcgtggatt ttctaagcaa
    29761 attccagatg ttgtctcatt aaatgcttct gatcttgctg cagccttcac tcatggagtt
    29821 gaaactgcgt ataaagcagt aatgaaacca gtagaaggaa cgattttgac agtagctaga
    29881 gaagcagcga aagctggaga aaagaaagca aaaagtactg atgatgtcgt tgaagtaatg
    29941 acagctgttg taaaaggagc aaagcgtgct ttagctaaaa ctccagactt gcttccagtc
    30001 ctaaaagaag tcggtgtcgt agacagtgga gggcaaggac tgctgtttgt ttatgagggc
    30061 tttttaagtg cattgaatgg agaattccaa gcggatgaaa catatgaacc ttctccagca
    30121 gaaatggatg atatggtcaa tgcagaacat catcgcagtg tccaaggtca aatggcgaca
    30181 gaagatatcc attttggtta ctgtacagaa atcatggtaa aaatcggaga aggacctaca
    30241 gtcgatagta cattcgatta cgaagaattc cgtaactatt tagatggtat aggagattct
    30301 ttacttgtgg tcaatgatga cgagatcatc aaagtccacg tgcatacaga aaacccagga
    30361 gaagtcttga attatggaca aaaattcggt tcattagtca aaatcaaagt cgacaacatg
    30421 cgcttgcagc atgagacgat tttggaacac gatgaagaag tgaacgagtt tgcgaaaaaa
    30481 gaaataccac gtatcccgta tggtatcgta gcgatcgctg ctggtaaagg cgtccaagag
    30541 ctgtttgaaa gtttaggcgc taattatgtt atcagtggtg gacaaacaat gaatccaagt
    30601 acggaagaca ttgttaaagc gattcaagaa gtaaacgcag ataaagtgat tgtcttgcca
    30661 aacaataaga acatcttcat ggcagctgat caagcagcag aagtagcaga tatcccagta
    30721 gcagttgttc cttcaagaac gatttcccaa ggattgacag ctatgctttc attcaatgat
    30781 caagcttctt tagaagaaaa caaagaaacg atgacagaaa tgttgtctag cgttgtgagc
    30841 ggtcaagtca ctcacgcgat cagagatacc tcaattgacg gtgtagagat caaagaagga
    30901 gactttttgg gcatgatcga tggaaaaatc ctgatctcta acccagatat cacagcaaca
    30961 gcgttaagta cactagaaca aatgatcaat gaggacacag agatcgtaac gatcttggca
    31021 ggtgatgaag gaacagttga acaagcaaat gaatttgctg agaaactaac agaaaaacat
    31081 cctgatttgg aaatcgagat ccaccaagga gatcagcctg tctatcctta tctattttct
    31141 gctgaataat ttctgtgtca gaatatcttt ctaacacagt attcattcat aaaaggcctt
    31201 cggttagtga tcaggtatga tcgctgacca agtccttttt ttgttaaagg agggaggaaa
    31261 aatttatgcg ttctttagat gatccaatca ctatgctggc aggagtcgga gaaaaaagag
    31321 cagctagtct tgccagcttg ggcatccaaa cgattgaaga cttactgact tattatcctt
    31381 ttcgctacga agatattcag gaaagaaatc taaacgagat ccaggatcaa gaaaaggtta
    31441 ctttgaaagg aatcgtagtc tcgcctcctg tgatgaatcg atttggttat aaaaaaagcc
    31501 gattgcaatt tcgtatgatg caagaacatg atgtgttcaa cgtttctttt tttaatcaac
    31561 cttatctaaa agaaaaagtc attttatcgg aggaaatcgc cgtatacggt aaatgggatg
    31621 caaagcgtaa agccttgaac gggatgaaga ttttaggttc tcaaacaatg gatgactttt
    31681 cgccgatata tcacgtcaac aaatcaattc gtcaaacgac attagttgat ctaatcaaaa
    31741 aagggtttca agaatacggc acattgattg aagaaaatct gccaaacaac cttgtggaga
    31801 aatatcgact gcttgaccga gcttctgctg taagaagtat gcattttcca aaagaccacg
    31861 aagaaaacca tcaagccaaa cgacgtgtcg tttttgaaga gttcttttta tttcaaatgc
    31921 gtcttcaagg attgaaaaaa gcagaaaaag cagaaacgaa tggtttggag atcctttatg
    31981 atgtccaaaa attgaaacaa tttactcaaa agctaccttt tgaactgaca aatgcacaaa
    32041 aacgtgtaac gaatgaaatc tgtcgggatc ttcgcagtcc gcagcatatg cagcgacttt
    32101 tgcagggaga tgtaggtagc ggaaaaacag tggttgccgc gattgcgtta tacgctaccg
    32161 ttacagcagg tttccaaggt gcgttgatgg tgcctacaga aatcttggca caacaacata
    32221 tggaaagctt gcaacagctg tttgatccca atgaagtaac catcgcattg attacggggt
    32281 caacgaaagc aaaagaacga cgtgagctcc ttgaaaaact agagcaaggg gaaattaacg
    32341 tcgtgatcgg cacacatgca ttgatccaag atggagtcga atttcagaat ttaggtctag
    32401 ttattacgga tgagcagcac cgttttggcg tgaaccagcg gaaagtactt cgtgaaaaag
    32461 gctggcgacc agatgtctta tttatgacag cgactccgat tcctagaaca ttagctatta
    32521 cagcatatgg tgagatggat gtatctatca ttgatgaact tccagctgga cgtatcccga
    32581 tcgaaacacg ctgggtaaga acacctcaat tggacagtgt actggattgg acgaaaaaag
    32641 aactggcaag aggacatcaa atgtatgtca tctgtccgct gattgaagaa tcagaagcat
    32701 tagatgtaaa aaatgcagtg gaaatctatg aaaaacttcg tgaactattt gcaccaaaat
    32761 atgaagttgg cttgttacat ggtaaaatga agaatcagga aaaagaagta atcatggaag
    32821 ccttcaaaga caaccagatg cagatattag tttcgactac tgtaattgaa gtaggggtaa
    32881 acgtgccgaa cgcgaccgtc atgctgatca tggatgcgga tcgatttgga ttggcacagc
    32941 tgcaccaact tcgtggacgt gttggacgcg gaagtgatgc ttcctactgt atcttagttg
    33001 ctaatcctaa aaatgaacta ggtgtggaac ggatgaaaat catgacagag accaccaatg
    33061 gttttgtact aagcgaaaaa gatctggaat tacgtggtcc tggtgaagta tttggcttcc
    33121 gtcaatctgg tctgcctcaa tttgcgattg ctgacttggt gacggatgga aatgttttgg
    33181 aggtagccag agaagaggct gcagcccttt ggcaaataaa ggattggcag atgcttcctg
    33241 agtatcagcc tttagcgcaa agcctccaaa tagaaaatca ggataatcgt tatttcgatt
    33301 agcagactgt gctatacttt atactgatga cggaaaaagg agtggaaaca atgaaaattg
    33361 ccgtagatgc aatgggcgga gatcacgcac ctcaagcaat tgtagaaggc gtggctttag
    33421 cgcagcaaga ttttccagaa gtagaattct tactttacgg aaaagaagca gaaatcaaga
    33481 aatacttaac aaatgaaaaa aacatcacga ttatccatac agacgaaaaa atcaatagtg
    33541 atgatgagcc agtaaaagca attcgacgaa aaaagactgc atcaatggtc cttgctgcac
    33601 aagcagtgaa aaacggtgaa gcagatgctg tattttcagc agggaataca ggcgcgctac
    33661 tagcagcagg gttgttcatc gtaggacgta tcaaaaatat cgaacgccct ggcttgatgt
    33721 ctaccttgcc agtagtaggg aaagaaggtg ccggtttcga tatgctggat cttggcgcta
    33781 acgcagaaaa caaaccagaa catttgttgc aatacggtat tttaggttct ttttatgcac
    33841 gtaaagtccg aggtatcgga cgtcctcgtg tcgcactctt aaacaacgga acagaagcaa
    33901 caaaaggtag tgaagtgacg aaaaaagcct atgaactcct tcagaatgaa acaagcttga
    33961 attttattgg aaacgtagaa gctcgtgagc tactcaatgg tgtggctgat gtagtggtca
    34021 cagatggatt tacaggcaac gctgttttga aatctattga aggaacagca atgaatatga
    34081 tgaatctatt aaaatctgct attctaaatg aagggatcaa aggaaaaatg ggcgctatgc
    34141 ttttaaaaga cggcttacgt tctttgaaag cagaaatgga ttattccaaa catggcggtg
    34201 ccgttttgtt tggcttgaaa gcaccagtca ttaaaactca tggagcaaca ggccccgatg
    34261 ctgttcgcta tacgatccgc caaatccaca caatgcttga gacagatgta gttggacaat
    34321 tagtcgaaca atttgaaaaa agcgaagaat agtatttgga tatctgaagc gatccgttcc
    34381 attgaaaaaa aggtggacat tcctgaaaaa tgccagtaaa attagccatg gtgtaggtaa
    34441 ttgacaagtg tatgattctt ggaggtgaaa aagttgactc gcgaagaagt atttaacaaa
    34501 gtagcgaaaa ttatttcaaa tcattttgag atagataccg ataaagtgac ggatgaattg
    34561 aacatcaaag atgatttaaa agctgattca attagtatta tggaattcgt tttagagctt
    34621 gaagatgaat tcggtacgga aatttcagat gaagacgctg aacaaattga aacagtcggt
    34681 ggcgcagtag attatatcag cagccatctt aaataatttc aaataaaagc aaagaaggat
    34741 aaaaagctgc atgcagcttt ttatccttct ttttttaatc tttttgacac gtaaaagtca
    34801 tttttctgat aattctggcg ataaacagaa attatgttgc aaagtaaagc ggttttctat
    34861 ataattatta ataattcatt acacaaagat aagaataacc tttgttataa aacgatttat
    34921 tctgtgtaat gtcctttttt attaagaaaa acttccattt aggaagcaga gaggggtatt
    34981 cgattgtccg ataaccaatt attagaagtt cagaacctac atacaggatt ccgactcaaa
    35041 gatgactatt acgatgcagt agatgacgtt tcatttactt tagacaaaaa cgagatttta
    35101 gcaatcgttg gggaatctgg gtgcgggaaa agtaccttgg ctactacgat tatgggatta
    35161 cttgatccta ataacacaaa aattacaggt gagattttat ataacgatct gaatttaatc
    35221 gacctgaacg aaacgctcta taataaaatc cgcggaaatg atatcggaat gattttccaa
    35281 gatccgttgt ctgcattaaa tcctctcatg agaatcgaag accagatcaa agaaggactt
    35341 tcctatcaca caaagatgaa tgcagaacag cgtcaagctc gtgcactaga attgctagaa
    35401 caagtaggga ttcctaatcc tgcgagagtt ggacgccaat atccccatga actatcaggc
    35461 ggtatgagac aacgtgtcat catcgcaatc gcaatcgcct gcaaacctcc aatcgtcatt
    35521 gcagatgaac cgacgacagc cctagatgta accatccaag cacagattct tgatttactg
    35581 aaagaccttc aggaagaaac aaaaacaggg atcatcttga tcactcatga cttaggagtc
    35641 gtagcagaaa tggctgatcg agtggcagtg atgtatggcg gacagttcgt tgaagtagca
    35701 ggtgtaaaag aactgtttga tcatcctaag catccttata cacgctcttt actgaactct
    35761 ataccacaag aaggaaatca tgatgcagaa ctccatgtga tcgaaggtgt cgttccttct
    35821 ctgaaaaaca tgcctcgtaa aggttgtcgg tttgcaccac gtattccatg gataccagca
    35881 agcgatcatg aagaagagcc tatccttcat gaagtcgcac cgaaccactt ggtacgttgc
    35941 tcctgctata agcatttcca ctttagagac gaaaaaggag aggtgtagat gacagaatta
    36001 atcacaatca aagacctgaa agttcattac cctattcgca gtggattctt caatcgagta
    36061 acggatcatg tatatgctgt agatggtgtg gattttatta tcgaaaaagg aaagacatat
    36121 ggtttagtgg gagagtctgg ctctggaaaa tctactacgg gaaaagccgt tgtgggatta
    36181 gaaaaggtaa cagccggaca aatcatgtat gaaggaaaag atgtaacgaa gcgaagcaac
    36241 cgcaaaaaaa tgggttataa caaggatgtg cagatgatct tccaagattc aatgtccagt
    36301 ttgaatccta aaaagcgagt gttggatatc attgctgaac ccatccgaaa ttttgaacgg
    36361 ttaagcgatc aagaagaaaa gaaaaaggta aaaggactgc tagatatcgt tgggatgccg
    36421 gaagatgcgc tatataaata tcctcatgaa ttttcaggcg gacaacgtca acgtctagga
    36481 gtagcccgtg ctgttgctac caatccaaaa ctgatcgtag ccgatgaacc tgtatctgct
    36541 ctggatctat ctgttcaagc gcaagtattg aatttcatga aacgaatcca gcaagaatac
    36601 ggcctcagct atttattcat ttcacatgat ttaggtgtag taaaacacat gtgcgacaat
    36661 atcgcaatta tgtacaaagg tcgatttgta gaaatcggta caagagaaga catttataat
    36721 gacccgcgac atatctatac gaaacgtctg ctttcagcta ttccgcaaat cgatgtagaa
    36781 aatagggaaa gccacaaaga aaatcgacga agagtagaac aagagtatat ccaaaaccaa
    36841 aaagaatact atgatgcgac tggtcgagtc tacgatttgc gtacgatcac aactacacac
    36901 aaagtggcgt tgaaagatgg aggtgcaagc taatgtggaa aacgattctg cgacgtgttt
    36961 tattgatgat cccgcaagtt attattttaa gtgttctgat cttcttatta gcccaagcga
    37021 tgccggggga tccatttacc ggtttgatca atccaaatca ggatccggca gtgatcgaac
    37081 agatgcgaca agcagctggc ttgaatgacc catggtatgt ccagtacttc cgttggatcg
    37141 gaaatgcttt gcaaggcgat tttggtcaaa gtttcttata caaacgctct gttgctgact
    37201 tgatcggcga acggatcatc aacactttat atctatcgat cttgacagtt gtccttactt
    37261 atttgattgc tgtgcctctg gggatgcttg ctggccggta tcaaaattca atcttggata
    37321 agattgtcgt aatctacaac ttctttagtt ttgctgttcc tttatttatc ttcggcttga
    37381 tcatgctatt tgtttttggt tatcgtttag gctggttccc aacaagtgga tcacaaacac
    37441 taggtttgca aggtggattt atcactcaat ggatagaccg tttgaaatat attctgttac
    37501 catcaattac ccaagcattt ttggcgactg ccgtcacaat ccaatatctg cgaagtgaag
    37561 taatcgattc gaaatcgctc gattttgtca gaacagcccg ttccaaaggg gtaccgacga
    37621 ataaagtatt cagtcgacat attttccgaa atgcagcgtt gccgatggct tctcaaatgg
    37681 ggtatgaaat cacttcgttg attgctggtt ctgtagttat cgaaaagatt tttggttatc
    37741 cgggagtcgg aaaactattt attgattcca tcggccaacg ggactatacc gtgatcacat
    37801 ccttagtatt gattttagga atcgcgacgc tagtggggac attactttca gatatcatca
    37861 tgagtatcgt tgacccgcgt attcggattc aataaaacca atcagaaagg agaatggatc
    37921 gatgagtgaa aaaaacaata cagcagttca agaaagtatt cctcctatgg ggatacgaat
    37981 gattgctcga gaatttaaaa aagataaaat tgctattttt tcattaggtt tgctagtggt
    38041 tttattatta gtgatcttta tcggtgcgat gctgaccgat caagacaaag tgatgtatgt
    38101 tagtatcttc gacaaatacg ctgcaccagg aacagtttcg acacaaggac aaaagttcat
    38161 tctgggagca gatgaaggcg gacgtgatgt attaggacaa ttgatcatag gtgctagaaa
    38221 ctctgttacg atcggatttg cgatcacgat ccttacttcg atcatcgggg ttggattagg
    38281 gatcatctct ggctactacg gagggatcat tgacaacatc ttgatgcgga tcgttgattt
    38341 tatcatgatt ctaccgatca tgctgatcat tatcgtcttc gtatcgatta tttccagata
    38401 caatgtctgg tcctttatat tcatcatgag tgcattttat tgggtagcta aagcccgatt
    38461 attccgaagc aagacattat ctgaagcaag aagagattat gtcagtgcct caaaaacaat
    38521 gggaaccaat gattttaaaa tcatgttccg cgaaatcatg ccgaatctaa gttcattaat
    38581 cattactaat ttgacgatga actttgcggc aaacatcggt atcgagacaa ctttgacttt
    38641 cttaggtttc ggcttgccgg caaatgtacc tagtttaggt acattgatcg gttatgcaag
    38701 taacggagaa gtcttagtga atcggcaatg gatctggtta cccgcatcaa tccttatttt
    38761 agttttgatg ttgagtatca attatgttgg acaagcattc aagcgttctg cagatgcgcg
    38821 ccaacggtta ggctagtata gaagcgaagg gggaaatagg aatgaagaaa acgatttttg
    38881 gatttgcagc gctgatgtct gctgtcgttc ttgcagcatg cgggggcgga ggtacagata
    38941 cctctggaaa caactctgga ggcaacggca ataacaaaga ggaattaact tttccaattg
    39001 caacaaaaaa taatgatgat gcaatcgaag acggcgaatt agaagctgcg gtcgcaacgg
    39061 acagtcagtt taaaggattg ttccagtggg agttttacca agattcatat gatgcagctt
    39121 ttatggctcc ttctcatgaa ccgctatttg caaacgatga cgatttcaga atcacagacg
    39181 acggagctgc aacgcttgat ctagatgaag atacgaaaaa agcgacaatc aaagtaaaag
    39241 acaacgtcaa atggtcagat ggtgaagatg taacggcgga cgatgtgatt ttcccttacg
    39301 aaatcattgg gaataaagat tacactggta tccgttatga cgacactttc cgtaacatcg
    39361 taggtatgga agaatatcat gatggaagtg ccgacacaat ctccggaatc aaaaaaatag
    39421 acgacaaaac agttgaaatc gaatataaag aagtaaaccc aagcatgctt caatcgggtg
    39481 gtggtatctg gtcatatgca gcaccaaaac atacgttaga aggtgtagca atcaaagata
    39541 tggaatcaag cgatcaagta cgtaaaaatc cagtgacttt tggcccttat tacatgagta
    39601 atatcgttgc aggagaatca gtagaatact tgccaaacga gcactactgg aatggtacgc
    39661 ctaaattgaa aaagatcacg atgaaatctg taccgatggc aagtgcaact gaagcattga
    39721 actctaaatt atatgatatg attttccaaa tgccaacaga tacttacgat acctataaag
    39781 aaattgctgg ctatacaaac ttaggccgtg aacaaacttc ttatacttat ctaggattca
    39841 agttaggtaa atggaatgca gatacaaaga gtgtggaata caatccagat tcaaaaatgg
    39901 ctgataaatc attacgtcaa gcaatgggct atgcattaga taataatgca gtaggtgaac
    39961 gtttctatgc aggtttgaga agcaatgcga cttcattgat tcctccagta ttccagtcat
    40021 accatgatga tgagatgaaa ggattcacac aagatctaga caaagcgaaa aaactattag
    40081 atgatgctgg ctacaaagat gtggatgacg atggtttaag agaagacaaa gatggaaata
    40141 aactaacaat caactttgct tcgatgtccg gtggggaaac agcgcaacca ttggcagatt
    40201 actatatcca acaatggaaa gaaattggtt tggatgtcca atacacaaca ggtcgtctga
    40261 tcgaattcaa ttctttctat gataaattag aaaacgatga tcctgaaatt gatgtttacc
    40321 aagctgcttg gaatacagga actgatccaa atccaagtgg actatgggga ccaaatgctg
    40381 cgttcaacta cactcgttat gaatcagaag aaaatacaaa attgatcaac gatatcagtt
    40441 caagcaaagc atttgatgaa gagtaccaaa aagaagcata tcaaaaatgg caacaatatg
    40501 catttgaaga agcatttgcg attccaacgt tgttccgtaa tgaagtattg ccagtcaacg
    40561 accgtgtcaa agactgggat tggtcttatg atgtaccaaa cccatgggca aatgtttctg
    40621 ttacagcaga ttcacgttca taatcactaa aaatgaccga aaaagggcga tgtccttttt
    40681 cggttttttg atatttttct gtttatttct ctaatattca ggtcaaggcg ctgatttcat
    40741 gacttctcca ataaacggtg ttcaaagtcc agtttctcgg tattaagtca aatttatgca
    40801 aaaatatgga aagccatttt cacaaaattt tttcttcata ctcgaaacta aacgaatttt
    40861 tcacaacttc tcgtcaatca ctaggattat taaagcttta cttacctttt gaccgaacca
    40921 tttcaaattt gacaaaaaac cagtataata aggaagtatc gaaaaaatat ccataaaagg
    40981 aatgtggaaa atggacaacc agctgacaaa agaactaaaa gaaaactata acatcgtttt
    41041 tcacgatcta aatttgcttg aacaagcttt tacccattca tcctatgtga atgagcatcg
    41101 caatctgcaa ttatcggata atgagcgact tgaattttta ggagatgccg ttttagaact
    41161 gatggtttct cagtatttat tccgtttata tcctcatttg ccagaaggaa aattgacaaa
    41221 aacacgagct gcgatcgttc gcgaagacag cttgtcgaaa tttgccaaag aatgtcactt
    41281 tgatcaatat gttttgttgg gcaagggaga agagaattca ggaggacgta cgcgaccagc
    41341 attgctttgc gacctattcg aagctttttt aggcgcgtta tatcttgacc agggattcga
    41401 cacgacccat gcattcatcg aaaaagtgat ttttcctaaa gtcaaagcag gtgctttttc
    41461 acatgagatg gatcataaaa caaaactaca agaagtcttg caaaaatcag gtgatgtatc
    41521 aatcgaatac cgattgatca atgaagaagg tccagctcat gaacgagtat tttggatcga
    41581 agtttatgta gatgatcaat tgattggcac tggacaaggg aaatcgaaaa aattagcaga
    41641 acaagctgcg gcggaaaatg cattggcagc actgtaaaag taagtgaggg aaagctttgt
    41701 atttgaaacg aattgaaata gccggtttta aatcatttgc agacaagaca gtcattgatt
    41761 ttgaaaatag cgtcacagca gtggttggac caaatggcag cggaaaaagc aatattacag
    41821 aggctatccg ctgggtatta ggagaacaat ctgctaaaag tctgcgaggc ggaaaaatgc
    41881 cggatatcat ctttgccggt tccgataccc gtaagcagct gaatattgca gaagtcacag
    41941 tgattttaga caatagtgat cattatctgc cattggagta caatgagatc agtgtaaccc
    42001 gccgttatcg acggactggg gaaagcgagt ttttcatcaa taaacaaagc tgcagattaa
    42061 aagatatcca agaattgttc ttagattctg gattaggaaa agaatcgttc tcaatcattt
    42121 ctcaaggaaa agtagaagcg attttcagta gtaaaccgga agaccgtcgt gggatctttg
    42181 aagaagcagc tggtgtcttg aaatacaagc agcggaaaaa gaaagcagaa cagaagcttt
    42241 ttgaaacaga agacaacctc agccgcgtcc aagacatcat ccacgaattg gaagaacagt
    42301 taactccttt ggccgcccag agtgaggcag caaaggagtt tttacggcta aaagaaacac
    42361 tgactcaaac cgatgtctct ttgatggttg ctgaaatcaa gacagcaaaa aaagattggg
    42421 acaacaaaca agcacagctt gcgaaattca atctagaatt aggcaaacta tctgagtcga
    42481 tccaagaaca agaatccatt ttggcgaagc agcgtaaaga aaatgcgcaa gccgatcgtc
    42541 tgatcgaaaa aaatcagcaa gtattattag atctttcgga aaaactgaag cagacagaag
    42601 gacaaaaaga tgttttgcag gagcggacaa agcatacaca aaaaagctcg caagaatatc
    42661 aaacttcatt agcagaagca caaaaaaagg ttaaacattt tgaaaagctt caagaaagct
    42721 tgatgaaagc agcagcagaa aaagaaacag agatccaaaa agctgaagca aatctcataa
    42781 aaacacagca agaattagaa aaataccaaa aatcaacgaa agaattattg gcagaattaa
    42841 gagatcaata tgttgatttg atgcaagaac aagcagctgt aggaaacgaa ctgaagtatc
    42901 tagaacgtca atatatacaa gaaacagcaa aaagcaagca gacgttagcc aagcaatcgg
    42961 aagtagaagc atcagtagac cgattgatct tacaaaaaga agaattgaca caaaagcagg
    43021 cgcagctaaa atcatcttta actgaaacaa aagagaagtt agaaatgatc caacaaaacg
    43081 ggaaaaagtt ccaagaagca ttagcaaaag aacagcctaa aatgtatcaa ttaatgaatc
    43141 aagtccagca gctacgtgct cgtaagaaaa gccttcaaga aatccaagaa aactattttg
    43201 gtttttacca aggggttcga ttggtcttgc agcataaaca gcagctttcg ggtattgtcg
    43261 gagcagtggc tgaactgatc gatgttcctg cagatttcac gttagctatc gaaacagctt
    43321 taggtggggc agcccagcat gtcatcgttg aaaatgaaaa agatgctcgg caagccatca
    43381 cgtatttgaa acagcaaaga ggaggaagag caacattcct tccactgacg acaatcaaac
    43441 caagacaatt accggctcat atattgacac aagcagcagc tgtagaaggg tttataggga
    43501 ttgccagtga acaagtcagt tatcccgatc aaatccaaac tgtggttcaa aacctgctag
    43561 gaacgatcct tttagccaaa gacttaacta gtgccaatgc aatcgcgcaa acgatccgct
    43621 atcaatatcg agtggtttcc ttagaaggtg atgtgatgaa tgccggagga tccatgacag
    43681 gtggagcgaa taaacgagga aaccaaggca gtttgtttgt acaaaatcaa gaattgaaac
    43741 agttgactag tgaatttgaa gaagcagata aacaactcca agcacaagaa aaaaaagttc
    43801 aggagctgca acaagaaaca gctcgtttag ccgaagaaca agaagttttg cgtacacgag
    43861 gcgaacaatt acgttttgaa gaacaagaag cgacaaatca gctacaaaac atcataaatg
    43921 aacttgaacg ttttgaaaaa gaaaagcaaa tctcaacttt tgagacacgt gaactgcagc
    43981 agtttatcga agattacgaa aagcaaacga acgaattgaa agacaaacaa acagatcttg
    44041 aatcgcaacg acaaaaaatc gacgaagaaa tcaaatcgtt aagtcaagaa agcgaccaga
    44101 tggaagccag aagagcacaa gtacaaagtc aaaaagcaca agaacaagca gatcttgctg
    44161 tcttgaaaga gcagtttaat catctgcaga tccagctccg cggtgcccga gtccaaaaag
    44221 cagaggcaac cgaacgtcaa gaagcgatag aaaagcagtt ggcgacattg acagcagact
    44281 tttctgatca tgaagtcaca gaagaaagtt tggaaaaaca aattaacgaa ttatctgctc
    44341 agcgagaaac attaaaagcc gagttggcaa aagccaaaga gcagcgagat agaaggcaaa
    44401 aggagatcga taagcttgaa gcagtcttgg cagagcgtaa tcgtgagcaa aaagcacgac
    44461 tgtcggaaca atccaaatta gaagtccaaa aagaccgagc tgaaatgatt ttagataatc
    44521 atttgaccta tctgcagtca gaatatcagc tgacatttga gaaagcttcc caagactatc
    44581 aagaaacaac cgatatcgaa gacagtagaa caaaggtttc atccttaaaa gaacagattg
    44641 aaaaactggg accagtaaac ttaaattcaa tcgaacaata cgaacaagtc agtgaaagac
    44701 atacattctt agcaacacag cgagatgatc tgttagcagc gaaaaaccaa ttgtttgaaa
    44761 cgatggatga gatggatgat gaagtgcgga caagattcaa agaagtattt gaagctatcc
    44821 gtcaagaatt caaaattgtc tttccaaata tgtttggcgg cggtaaagct gaattagtac
    44881 tgacggaacc aactgatttg ctgaaaacag gtattgagat tgaagtacaa cctcctggca
    44941 aaaaactgca aagtctaagt ttgctttctg gaggagaacg agcacttaca gccatcgcgt
    45001 tgctcttttc cattatccgt gtctgtcctg ttccgttttg tatcttagat gaggtagaag
    45061 cagcgttaga tgaagccaac gtgaaacgtt ttggtcgtta cttgagcgat ttccaagatg
    45121 acacacaatt tatcgtagtc acacaccgca aaggaacgat ggtcgcagca gatgtactgt
    45181 acggagtgac gatgcaggaa tccggtgtat caaaaatcgt ttctgtacgg atggaagata
    45241 tcaatgaaga ggcgaaaatc aacgaaacga aagtgtagga acgaaaatga tcaaattagt
    45301 agcaatcgat ttggacggta cattattaaa tgaacaaaag ctgatttcag atgagaataa
    45361 acaagcatta gcacaagcaa aacagcaagg ggtcaagatc gttctatgta caggacgccc
    45421 cttagctgcg atggcgcatt atctgcaaga attaggactg gtagatgaag gtgactacag
    45481 catcactttc aacggcggtt tggtacaaaa aaatgatact ggtgaaatca tggaaaagaa
    45541 agtgatggaa gtatcagata tccaacgctt atacaaactg gctcagcaat tggatctgcc
    45601 actagatgtt ttgtctgaca atgtggtttt acagctgcct agtgccccaa ggaagcaatc
    45661 cttgtacaat gtgttgaata agctgctgca attccaacca gcggatataa gcgatattac
    45721 agatgaattt gtgcttaata aggcagtaat cgcttatgac caagaagaat tagatcctaa
    45781 aatcaaagaa ataccagcag aattccatga aatgtatgag atcatcaaaa caagaagtat
    45841 gcttttggaa tttatgccaa aaggtgttac aaaagcttat ggtatttctt tattggcaaa
    45901 agatcttggt ttgaaacaag aagaaatcat ggcgatcggt gatgaggaaa atgatttacc
    45961 gatgatccaa tatgctggac taggcgtagc gatggagaat gctgtgcctt tcgtcaaaga
    46021 agcagcagat ttcgtgacag ccagcaatga agaaaatggc gtagccaaag tgatccaaaa
    46081 atttgtatta gagtaggggg agtcaaatgg gattttttga taaaatcaag cgtgctttta
    46141 ctggcgaaga gaaaacagaa gaagttgaag tacaggagaa gtacgacaag ggtttagaaa
    46201 agacgcgtaa aacatttggt gaacggatga atgagttgtt tgccaatttt cgaacagtcg
    46261 atgaagactt ttttgaagaa ttagaagaaa cacttatcgg tgcagatgta ggttttgaaa
    46321 cagcgatacg aattaccgaa gcattacgtc aagaagtgaa actcagaaat gcgaaaaaat
    46381 cggcagaagt ccaaaatgcg atcatcgaga aacttgtgga tctctatgaa gcggaaggaa
    46441 tcaatgaagt aaatgaacta aatatccaag aagacggact aacagttatt ttgtttgtcg
    46501 gtgttaatgg tgtagggaaa acaacaagta ttggtaaact tgcccatcag ttcaaaaacg
    46561 aaggtaaaaa agtattgatg gcagcagcag ataccttccg cgctggagca atcgaccagt
    46621 tagttgtctg gggcgaacgc gctggtgttg aagttgttcg tggcaatgca ggaggcgatc
    46681 cagcagctgt cgtattcgat gctttggaaa gagcaaagac agagcaggca gatgttttac
    46741 tagttgatac tgcaggccga ctgcaaaata aagtgaactt gatgaacgaa ttagaaaaaa
    46801 taaaacgagt aatccagcgg gaattaccag aagcacccca agaaacactt cttgtattag
    46861 atgcaaccac tggtcaaaac gcgatggttc aagcaaaaca attcaaagaa acaacagatg
    46921 tgaccggtct tgttttgaca aaattagatg gtacagcaaa gggcggtatc gtacttgcta
    46981 tccgtaatga attgcattta ccagtgaaat tggtcggtct tggtgaagga atcgatgact
    47041 tggagccgtt tgatccaaat gattttgtcg ttggattgtt caaaggatta ctaaaagaag
    47101 aataacccat gtctaaaaag caggagctgt gacaaaagtt gcagctcctt gtttgaatga
    47161 ttgtttttaa catagctgtg tttttgatgc cttcattttt atacttattt gtaagcggtt
    47221 ctcaaacaat ttcgttcttt ttcttagact ttttgattat aattagattc atatgaattg
    47281 gaggtcactt aatgatgaat tttaagcaat tattattgca tgtcaatgcg cgccctttta
    47341 tcgaccaagc tcgatttggt atagaacggg aaggacagcg ggttgatctt gcaggaaatc
    47401 tagcaaaaac cgatcatcca gcaatctttg gcgatcgatc ctatcacccc tatatccaaa
    47461 cagattttag cgaaacacaa acagagatga tcacccctgt taccgattct attcccgaat
    47521 tatttcagta tctcgctgct gtttatgatg tgactgctcg ttctataccg aaagaagaga
    47581 tgatctggcc attaagtatg ccacctgcct taccggaaaa agacgaagag atcattattg
    47641 caaaattaaa aaatttcgaa gatgtcttgt atcgacgtta tttagcaaaa gaatacggga
    47701 agcgaaaaca gatggtaagc ggtattcatt tcaattttga atttggcgat gagttgctaa
    47761 gaacattgtt cagccatcag gaagaatttc aagatttttc cgaattcaaa acagaacttt
    47821 atttgaaaac agcgagaaac tttatgcgct atcgctggat gatcacttat ttattcggtg
    47881 cttcaccaat gagtgagaag aactactttt tagatgaatc acatccgcaa gaacctgttc
    47941 gcagtattcg caacagtgcg ctgggctata cgaatcatcc aaatgtgaaa gtttcctatg
    48001 cttctatgaa acagtattta gcagatatcg agcgaatgat cgaagaaggg aaactttcgg
    48061 aggagaaaga attttataca ccgcttcgtt tccgaggcgg aaagaaagtc gcagatttag
    48121 caacaacagg tgttcgttat attgaattgc ggaatatcga tttgaatcct tatgcaagat
    48181 tgggtatcaa tccagagcaa gttcggttct tacaattatt cctgatgtac atgttatgga
    48241 cagaagaaaa agaagactgt gaccaatggg tagcagaagg tacgactcga aataacaaag
    48301 tagcactaga acaaccatca gatcaaacag aatttcatca agaaggtaga gaaattcttg
    48361 aaggaatgaa gcaaatgctg gttgaattgg attggttgga ttctctttat ttagtagagg
    48421 aagcattgac tcaaatggat catcctgaac aaacgttagc agcgaaactc tatcaagaag
    48481 cacagctatc gagtcagcaa gaagttgctg tggcattggg acatcaatat tataaagaaa
    48541 gccatgaacg tccctatcag ttggccggtt ttcgcgaaat ggaactttct actcagatat
    48601 ttatgttcga tgccatccaa aaaggtgtcc aagtcaaagt attagatgag tcggatcaat
    48661 ttttgcgtct gcaattccaa gaccatgtag aatatgtgaa aaatgcaaac atgacaagta
    48721 aggacagcta tatcgtccca cttatcatgg aaaacaaaac agtaacgaaa aaagtcttaa
    48781 aagaagctgg gttccgggta ccaggaggcg cagaattttc atccatggaa gaagcggtaa
    48841 aagcttatcc gagatttgcc gagcaggcat ttgtgatcaa acctaaatca accaattacg
    48901 ggttaggtat cacgattttc aaggaaggag ctagtctgga agattatcaa gcaggtttag
    48961 ccattgcttt tcgtgaagac agttcggttt tagtagaaga atttatgccg ggaacggaat
    49021 atcgtttctt tgtgatcgac ggagaagtcc aagccatcat gttgcgagtc cctgctaatg
    49081 ttattggtga cagtatccga acagtgaaag aacttgttga agaaaaaaat agtgaccctt
    49141 tgcgtggaac gaatcatcgt gcacctttag aattgatcca attaggtgaa ttagaacaat
    49201 tgatgttgaa agaacaaggg ttgacgatcg aatcagttcc ccaagccaat caaattgttt
    49261 atctaaggga gaactcaaat atcagtacag gtggtgattc gatcgatatg actgatgaat
    49321 tttctgaagc ttacaaaaaa atcgccgttt ctgcggtaga agcactagga gctaagatta
    49381 gtggtatcga tttgattata ccagataaag aaatcgatcc tacaactgat aaaaaagcat
    49441 atgggatcat cgaagcaaat ttcaatccag ccatgcatat gcatgtttat ccttttgcag
    49501 gaaaaggcag aagattgacg atgaatgtat tgaaattgtt atatcctgaa gtattttaaa
    49561 agaaaaagct tttgacagat tgtcctattt gatgtcaatc tgatcaaaag ctttttttgc
    49621 atgtaaaaat ttatgtgttt tttcgtttta aaataaacga tcccagaagc tttttttctt
    49681 ttttggtttt tctttttcag ctggcgaaga gttttcttct gggtattttt tttcgatatc
    49741 aatcacaggt tcatttactg cttcttttgc tgttaagagc aatccgaatt cctcaggatt
    49801 tgcagtgacg taatcgttga ctacagtgaa acggctattg tttttcgttg ctagctggat
    49861 atattggttt tggacagaaa ggggtagagc cccattcaag agtatggaag catctggatg
    49921 ttttttgagt tcttttaaaa agttttcttt gttttttggt tggatcattt cagcaacagt
    49981 catactaaga tagcagcgtt ccctgaatgt ccctaaatat ttatgctgtt cttcagggtt
    50041 cactaaaggt gtaccataaa gtcccttatc caaatggctt tttacatcat cttgtgccat
    50101 aaaaaatacc ctccttcttc tctttgtctt tcttacgatt atagcatatt cccaataata
    50161 cctaaaacat atgaaaaagc ggttgctttt gttcaacgat tcacttaaaa taagaatgaa
    50221 aatcattctc aattagaaag gtggattgga tgcgctacgg acgactagta gcattattag
    50281 ttattttaag tagtatttca ttgttcatcg gagtatcgaa tgtacaattg tcagaactgc
    50341 tccagttaga tgggcaaagc ttacaaatct tgctagtgac tcgtttgcca cgaacgattt
    50401 gtttgatcct tgtgggagcg accagtagta tttgtgggtt gatcatgcaa catttgaccc
    50461 aaaataaatt tgtttcacca acgactgcgg gcacgatgga tagtgcgcgt ttaggtattt
    50521 tagtggctat gattttccta cctggtgcat ccttgattgt ccgatccttg acagcatttt
    50581 gctttgcttt tgcaggaaca ttgctttttt tatcccttac gcgattgttc ctccagaaaa
    50641 atcaattgat gcttccgttg attggagtca tgttagggaa tatcattggt tcagttgcta
    50701 ctttttttgc ttatcaattc cagttggtac aaaatatgac ttcatggctt caagggaatt
    50761 ttgcgactgt gatacgagga aattatgagt tattgtatgc tgttgttcca ttgttgctct
    50821 tggtttggct atttgcttac cgatttacga tcattggtct gggcgaatcg tttgcagtaa
    50881 atctgggaat agattaccag aagatgcagt ttttaggcat tggcttagta tcattggcta
    50941 gtgcagtcat gttgatcatg gtaggaagca ttccttttat cggagtgatc attccgaatc
    51001 ttgtctctag aatatatgga gatcaagtgc acaaaacaat tggcgtaact gctttagcag
    51061 gtagtttgtt cttagtattt tgcgatcttg tcgctcgcgt gttgattttt ccttatgaaa
    51121 taccagtcag tgtgatcgtt ggaatcatcg gtggggctat cttcctttat cttctgataa
    51181 ggggacgacg atatgcttaa aaaaaagcca tctattttta ttggtatgct tgttcttgtt
    51241 ttatttgtta caggaatgta cttgacgatc catacatatg gaaactggca ttttgcatgt
    51301 gcattgagga gtaagaaaat ttttgcattt atccttgtct cgctagctgt cagcagtgcc
    51361 acaatcagct ttcagacaat tacgcataac cagtttttga ctccttcagt attgggactt
    51421 gagtcgttat atgtccttgt ccaaacggtc cttttcttct ttatcggagg agtgacgatg
    51481 cttcagcaga caggtacagt ttttttctta ttgaacgttg ggctgatggt cgggctgagt
    51541 ctattgttat ttttctttct tttgaaaaaa atgagagcga atcttttttt attactgatg
    51601 tcagggatga ttttaggtac gctttttggt agtgtcagta cctttttaca agtcatcatg
    51661 gatccgaatg aatatgattt gcttcaaggc agattatttg caagctttgg caatatccag
    51721 agtcagtatc ttttgcctgc ttctttgatc attatcggct gctggtacct gttatttcga
    51781 tatcgacatg tgctagacgt tttccatctc ggaaatgaac aagcagtaaa cctcgggata
    51841 gacacagatc gttttgaatt tttgatttta tgttgtgtca gtcttttgac agggacatca
    51901 acggctcttg tgggtccagt tactttttta gggtttattg tcgcaaatat cagttatcgt
    51961 gtcttttcta cttatcgtca tggtcagcta tttatcggaa gctttctggt agctatgctg
    52021 tttctgacag gaggacagct cgcagtagag cagattttcg gctggaatac aacagtgagt
    52081 gtcgtcgttg aatttgtcgg aggaatttat tttgtcacaa aattgattcg cgaaaggaag
    52141 agtatcctat gattgattta caaaaggtca ataaactgta ccatggaaaa tcagtggtta
    52201 aagatgtaca gttaacgatt cctgaaaaga aattgactgc ttttatcggt ccaaatggtg
    52261 ctggaaagtc aacggtgttg tcgatgatca gtcgtttgat accaaaagat acaggtgaaa
    52321 tctatttaga ccataacgaa gtaaaggctt ggaaatccaa tgaattagcc aaaaaattat
    52381 cgatcctacg acaatcgaat gaaataaatg tccaaatcac cgtgaaagaa ttagtagaat
    52441 ttggacgatt tccttatacg aaaggaaaat tgacgacaaa agacgaggaa atcgttcagg
    52501 aatcactgga acaccttggg ttagaagaaa tagcggatca atcgattgac actctttcag
    52561 gcggtcaact ccaacgtgcg tatattgcaa tggtgctagc gcaagacacg gattatattt
    52621 tactggatga acctttgaac aatctagata tgaattttgc ggttcaaatc atgcagattt
    52681 taaaaaattt agtacaagaa atcgggaaaa caattgttat tgttcttcat gatatcaact
    52741 ttgctgcaag ttatgcagac gaaattgttg caatgaaaga tggacagtta tttacgcaag
    52801 gaacgaccca agaaatgata aaaaaagatg tattggatga attatacgaa atggacatac
    52861 ggatttgtga gattgaaggc cgcagattct gtctttattt ctaaaactaa cattaggaga
    52921 gaagagatga aaaaattagt agtaggtatc ttgattctag catcatttgg tttagcagca
    52981 tgtggaaata gcaacaacac cagtcaggca gacacaaaaa aaagcagcac acaaactgaa
    53041 actacattga cgataacaga tagtaatgga gaccaaatcg aggtgccaaa taatccagaa
    53101 aaagtcgtcg tattcgacaa tggttcttta gatacgatgg atgctcttgg tgttggagat
    53161 aaggtagttg gagcagctac aagcagcctt cctgagtatc tttcatccta taaaaaagta
    53221 gaatcagcag gtggaataaa agaaccagac ttagaaaaaa ttaatcagct tcagccagat
    53281 ctaatcatca tttctggccg acaaagagat tttcaaaaag atctaagtca aattgctccg
    53341 accattttcc tttctttaga tgcgaaaaat ccatgggaat ctttccagca aaatgtcact
    53401 gctttagggg agatctttgg taagcaagaa gaagctaaaa ctcaattaga ggaattatct
    53461 agtgcaatcg atcagacgaa aaagaaagca gaagctactg acaaaaaagc actagtcaca
    53521 cttgtgaatg aagggcaatt atcagcctac ggatctggtt ctagattcgg tttcatccat
    53581 gatttatttg gctttgaaca agcagatgat caaatcgaag catccactca cggtcaaagt
    53641 gtttcttatg aatatgtgct ggaaaaaaat ccggatatct tatttgtagt agacagaaca
    53701 aaagctattg gtggagacga cagcaaagat gatatttctg ccaatgaact ggtagcacaa
    53761 acgaatgctg gtaaaaatca gcagatcatc tcccttgaac cagatgtctg gtatttaagc
    53821 gggggcggtt tagaatcaat gaaactgatg atcgaagatg tgaatcaagc atttaaatag
    53881 cataaataac agaggattaa actctcatac tatgtaacaa taatgtttct tacattctta
    53941 aatagcaaga gcctatcctc aaagaagtta tcaaaaacca tccgtaaaat cgtattgatg
    54001 attttacgga tggtttttat ttatttgaga aatctttttt caacgtgaat tcattatcta
    54061 catcatacgg gttgattcta gaatggggag tggcaaaaaa tagtgtgatc cattttttca
    54121 gcatcaagat cgcctccttt gatttgaatc aaaggtacaa agcgaaactt agataaaact
    54181 taaatttaga tatttttatt ttgtaccgat ctcttcttta aacgatgttc catctgctgc
    54241 ttctcggcaa taag
//
LOCUS       DACGMI010000011        54006 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.011, whole genome shotgun sequence.
ACCESSION   DACGMI010000011 DACGMI010000000
VERSION     DACGMI010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.011"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            135..2606
                     /locus_tag="IXT46_000773"
     CDS             135..2606
                     /locus_tag="IXT46_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4946709.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2709..4445)
                     /locus_tag="IXT46_000774"
     CDS             complement(2709..4445)
                     /locus_tag="IXT46_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAQ4946710.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4442..5146)
                     /locus_tag="IXT46_000775"
     CDS             complement(4442..5146)
                     /locus_tag="IXT46_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4946711.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5277..5780
                     /locus_tag="IXT46_000776"
     CDS             5277..5780
                     /locus_tag="IXT46_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAQ4946712.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            5740..6078
                     /locus_tag="IXT46_000777"
     CDS             5740..6078
                     /locus_tag="IXT46_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAQ4946713.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6099..7517
                     /gene="ffh"
                     /locus_tag="IXT46_000778"
     CDS             6099..7517
                     /gene="ffh"
                     /locus_tag="IXT46_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAQ4946714.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7629..8207
                     /locus_tag="IXT46_000779"
     CDS             7629..8207
                     /locus_tag="IXT46_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAQ4946715.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8211..8732
                     /locus_tag="IXT46_000780"
     CDS             8211..8732
                     /locus_tag="IXT46_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4946716.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(8811..9365)
                     /locus_tag="IXT46_000781"
     CDS             complement(8811..9365)
                     /locus_tag="IXT46_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAQ4946717.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9618..9893
                     /gene="rpsP"
                     /locus_tag="IXT46_000782"
     CDS             9618..9893
                     /gene="rpsP"
                     /locus_tag="IXT46_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAQ4946718.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            9905..10156
                     /locus_tag="IXT46_000783"
     CDS             9905..10156
                     /locus_tag="IXT46_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAQ4946719.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10281..11072
                     /locus_tag="IXT46_000784"
     CDS             10281..11072
                     /locus_tag="IXT46_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946720.1"
                     /translation="MRKKMLFIPFALLLSDCSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11242..11763
                     /gene="rimM"
                     /locus_tag="IXT46_000785"
     CDS             11242..11763
                     /gene="rimM"
                     /locus_tag="IXT46_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAQ4946721.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            11753..12514
                     /gene="trmD"
                     /locus_tag="IXT46_000786"
     CDS             11753..12514
                     /gene="trmD"
                     /locus_tag="IXT46_000786"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAQ4946722.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12650..12997
                     /gene="rplS"
                     /locus_tag="IXT46_000787"
     CDS             12650..12997
                     /gene="rplS"
                     /locus_tag="IXT46_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAQ4946723.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(13129..14265)
                     /locus_tag="IXT46_000788"
     CDS             complement(13129..14265)
                     /locus_tag="IXT46_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4946724.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLQKPNLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKMPETYIVSGINTVDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PINEVVIDYKRESKTIKIKDKFLEDDEYKRLVDFTTSHNKRYSLLFQWLYLTGMRPGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPKGQFLFQTTKGTPFQLTAINTYLRNHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(14382..15074)
                     /locus_tag="IXT46_000789"
     CDS             complement(14382..15074)
                     /locus_tag="IXT46_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946725.1"
                     /translation="MKKVILGLVFGAFFLTGCSQSNVVDNTGKTNEKDSSVTLSESTT
                     QSSKNSQEVDGPLLKVGQWTKEKRDTSGKIELIGTASPQSDIPLGDIGIYISNIKLLK
                     YSNYADPSAAGYYDANNHKDSEGNFYGLQIAFKVKNNSEVDYGYNGLAHAILDNGQQI
                     DFSSDDLMHTMTTNSFFKKTESKEFYSLAYLDPSKVNDITKVTIKTGVLYNPSDYSTV
                     AESAESTFNINR"
     gene            complement(15212..15865)
                     /locus_tag="IXT46_000790"
     CDS             complement(15212..15865)
                     /locus_tag="IXT46_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946726.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETKVSKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQATAEPSPTVISSSQDTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     GQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFSKYGIQ"
     gene            complement(15915..16343)
                     /locus_tag="IXT46_000791"
     CDS             complement(15915..16343)
                     /locus_tag="IXT46_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAQ4946727.1"
                     /translation="MEMDTINLVEELKRKYRSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRGRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKKIDELKNLYGLPESAYRFLI"
     gene            complement(16348..16722)
                     /locus_tag="IXT46_000792"
     CDS             complement(16348..16722)
                     /locus_tag="IXT46_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4946728.1"
                     /translation="MNLLDRIKELAHKRGISITQLEEELNIPKNTIYQWKNRTPSTKR
                     LQLVADYFNVTTDYLLGRNQVPDWATKDEVVELDKLLDSNVNMSYGGETLTPEQVQRV
                     KDILIGTFWDIVKEDKEKGKKM"
     gene            17007..17192
                     /locus_tag="IXT46_000793"
     CDS             17007..17192
                     /locus_tag="IXT46_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4946729.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALVGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            17205..17453
                     /locus_tag="IXT46_000794"
     CDS             17205..17453
                     /locus_tag="IXT46_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946730.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKITPKEFIEKHLVDL"
     gene            17484..17663
                     /locus_tag="IXT46_000795"
     CDS             17484..17663
                     /locus_tag="IXT46_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946731.1"
                     /translation="MGKFNRALVFSTPFIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(17706..18176)
                     /locus_tag="IXT46_000796"
     CDS             complement(17706..18176)
                     /locus_tag="IXT46_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946732.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            18263..18961
                     /locus_tag="IXT46_000797"
     CDS             18263..18961
                     /locus_tag="IXT46_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAQ4946733.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            19139..19480
                     /locus_tag="IXT46_000798"
     CDS             19139..19480
                     /locus_tag="IXT46_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946734.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            19473..20144
                     /locus_tag="IXT46_000799"
     CDS             19473..20144
                     /locus_tag="IXT46_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAQ4946735.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            20150..20836
                     /locus_tag="IXT46_000800"
     CDS             20150..20836
                     /locus_tag="IXT46_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946736.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGREISLK
                     DESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVTNFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            20839..21066
                     /locus_tag="IXT46_000801"
     CDS             20839..21066
                     /locus_tag="IXT46_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946737.1"
                     /translation="MINLNAVAFEQTWRTKYKKMSPRDKLFLEIMTFAFIGTQAEQSD
                     ISVEKIKTNRLVNGITETCYQYTIIVVDEEE"
     gene            21069..21896
                     /locus_tag="IXT46_000802"
     CDS             21069..21896
                     /locus_tag="IXT46_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replisome organizer"
                     /protein_id="HAQ4946738.1"
                     /translation="MAERRMFAKTIIDSDAFLDMPLSTQALYFHLSMRADDDGFINNP
                     KKIQRMVGCGDDDLKLLMAKRFILVFESGVIVIKHWKIHNYIRNDRYKPTLYQDEKAL
                     LADKDNKAYTFAEELSKHDEKLGIPDDNQAVYQMDTQVRLGKDRLGKDSKEIKDLTPS
                     KKSKAKPIRHKYGEYKNVLLSDEQMEKLKTEFPNDYQERIERLSEYCESSGKTYKNYL
                     ATIRSWARKEKSEPKNASSGYKRTGRREKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            21908..22177
                     /locus_tag="IXT46_000803"
     CDS             21908..22177
                     /locus_tag="IXT46_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946739.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGINNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLSELEQV"
     gene            22339..22641
                     /locus_tag="IXT46_000804"
     CDS             22339..22641
                     /locus_tag="IXT46_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946740.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVTEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEKK"
     gene            22638..22949
                     /locus_tag="IXT46_000805"
     CDS             22638..22949
                     /locus_tag="IXT46_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946741.1"
                     /translation="MNELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            22946..23164
                     /locus_tag="IXT46_000806"
     CDS             22946..23164
                     /locus_tag="IXT46_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HAQ4946742.1"
                     /translation="MIGLTIFWCAIGGLLAFLGYYLICESRKGRKYTVTGIVLLIIGI
                     LVAVGAELNLYVNGTQEDLVRFMFWMKN"
     gene            23175..23990
                     /locus_tag="IXT46_000807"
     CDS             23175..23990
                     /locus_tag="IXT46_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HAQ4946743.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            24129..24485
                     /locus_tag="IXT46_000808"
     CDS             24129..24485
                     /locus_tag="IXT46_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAQ4946744.1"
                     /translation="MDLITQYSDIILKKIMAKIQKDKKAKERAELVKLEMAETGVGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKAHSIQHGFI"
     gene            24445..24690
                     /locus_tag="IXT46_000809"
     CDS             24445..24690
                     /locus_tag="IXT46_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946745.1"
                     /translation="MIKKLIQFSMDLYDIESGATVSVESDHLIISFADERQIIIWVVD
                     DMLYPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSK"
     gene            24687..25085
                     /locus_tag="IXT46_000810"
     CDS             24687..25085
                     /locus_tag="IXT46_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946746.1"
                     /translation="MIPKFRAWDKRENTMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVEIFEGDVVITSKGAIGYVAYLQQEAGFVVVLKKSDYRLG
                     HRNTGESYDVATAHEVIGNIYENSELLEVE"
     gene            25082..25420
                     /locus_tag="IXT46_000811"
     CDS             25082..25420
                     /locus_tag="IXT46_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946747.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            25417..25647
                     /locus_tag="IXT46_000812"
     CDS             25417..25647
                     /locus_tag="IXT46_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946748.1"
                     /translation="MKYEIPLSEAGIQAIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            25654..25857
                     /locus_tag="IXT46_000813"
     CDS             25654..25857
                     /locus_tag="IXT46_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HAQ4946749.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASETIRKFGISILNDDRKWEAER"
     gene            25854..26147
                     /locus_tag="IXT46_000814"
     CDS             25854..26147
                     /locus_tag="IXT46_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946750.1"
                     /translation="MKLKDGFYTDAYGIGGLMMDLPTKNPIKQEESEIKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKRLAKSKENLAVVRLVDMEVIKS"
     gene            26177..26617
                     /locus_tag="IXT46_000815"
     CDS             26177..26617
                     /locus_tag="IXT46_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4946751.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            26692..27159
                     /locus_tag="IXT46_000816"
     CDS             26692..27159
                     /locus_tag="IXT46_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAQ4946752.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQPR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            complement(27559..27912)
                     /locus_tag="IXT46_000817"
     CDS             complement(27559..27912)
                     /locus_tag="IXT46_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946753.1"
                     /translation="MAKIDDYRSDMIEYIELFAKNSNNNIIIQTGGATICGTPIDFDA
                     EVKVNPLIDAMMDSFAEFRSKKIDDIEKDDEQSLVVKSIFLKDVTIIGERTTNIPFLV
                     VFADQISAISLGNLE"
     gene            28459..28671
                     /locus_tag="IXT46_000818"
     CDS             28459..28671
                     /locus_tag="IXT46_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946754.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQSKYFYDQL
                     ILQGFNEGQAMEFMMRTFSASNQQKE"
     gene            28678..28905
                     /locus_tag="IXT46_000819"
     CDS             28678..28905
                     /locus_tag="IXT46_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946755.1"
                     /translation="MRNYWYISLTNEYPRTIDDCSVRVVRSVQIKKKYSIIEMTREAT
                     PNEIDKYNLRYCGHGYWKDEYIQQNIERYIK"
     gene            28902..29186
                     /locus_tag="IXT46_000820"
     CDS             28902..29186
                     /locus_tag="IXT46_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946756.1"
                     /translation="MNDNYDYIKLIEKIRAEKDMDELANLFMNIISLVGLKMDEVAAL
                     NYFIAEQTIRAEHNAKFLKDRLDLDVKGLGVEGIFKVQEALVNVYVEKMQ"
     gene            29227..29799
                     /locus_tag="IXT46_000821"
     CDS             29227..29799
                     /locus_tag="IXT46_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946757.1"
                     /translation="MKLKDYIREGYNIVTTPNLAYKIQEDYPNVLVFTDRALDAIPIG
                     KLLVDRYYSNNPAVLSAKPLQNAYAIERFTCEFTGYETVVPMTGETGRKVIQQIKKRI
                     AELTLDDGSNTNLLEIKLRDTDSVPEVYYKGQRMDEMPIGLVDITYHWHTEEYECQVP
                     KGANDITIEYYDSHNNKYLDRKIIGHKRDM"
     gene            29800..30111
                     /locus_tag="IXT46_000822"
     CDS             29800..30111
                     /locus_tag="IXT46_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAQ4946758.1"
                     /translation="MIDVSTKQARARFYGSTEWRKLRSQCLERDHYECQWCKAEGRLT
                     TQHDSILEVDHIKELEYHPDLALDINNLRTLCKDCHNKRHNRMKYRGQQKKRKWDDEW
                     W"
     gene            30102..30362
                     /locus_tag="IXT46_000823"
     CDS             30102..30362
                     /locus_tag="IXT46_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946759.1"
                     /translation="MVVRKTANRDDVKRAEAIAMVDKAIDKLVLFKSQLIEETTTVED
                     ISINNRLIGNANEVTGTFNINVDIDYTLSPFAHIVESNEQDG"
     gene            30530..31084
                     /locus_tag="IXT46_000824"
     CDS             30530..31084
                     /locus_tag="IXT46_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016630802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4946760.1"
                     /translation="MIGLNSKLVGTRMKQKRIEKGLTQADVATKSGISSRYYGSIENG
                     KNSPSIETLNSISIVIGCSLHFLLNDRMDDMEKRVELEKKRLQKIFDKIPHDKLNLVE
                     GLIIQAARLRVLLDDNWKDIIENGEYEKFKQSENQIAYDRKRPIVENYDNRDKTYQAI
                     VKQLTDLLPQGTRADKKSKLLGRK"
     gene            31087..32778
                     /locus_tag="IXT46_000825"
     CDS             31087..32778
                     /locus_tag="IXT46_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAQ4946761.1"
                     /translation="MLFNQHVDQYIRKWKSGELILNEKRIQLLKLIEKEILPRDDIYY
                     FDEEQINNYIEFSQAWYFELDEWEKFISAFIFLFYKEDDEVVFDEFVINMGRGGGKNG
                     FISTLANYFVSSLHGIDYYDVSIVANSEKQAKRSFQECYRVINKKGNEDLKEEFEAYK
                     SSLTGLETQSVFEYKTSNASSQDGGREGAVIYDEYHEMENTDIVDVFSGGLGKVDHGR
                     QFFIGTKGFVREGYFDIKYRECEDILNGLSEFKGVFPYICELDAIEEMDDPKNWPKAN
                     PALQPPLNKRGKRLFNEVMKKYKKLAKEPSGRSAFVTKRMNFLEDNMENSVASREEIM
                     ATNRPFFELDTVPIGSLDFGSVRDFATCGLLFKNRKKSEYAFKSFTFAMKNFCDVHYG
                     YSLKEQLVGSEKRAPIKTWEKMGLMKVIDEPSLNPKYIVDWFIQAREEYGVRVIVVDN
                     YKADILGPMLEKEGFEVVRLKRPSSLHPLLAPRIEDGFANHKFIFGDNPLMRWFTNNV
                     YVKETQAGKQFLKKEEVKRKTDGFQAFVHALYKATELDEQIDYDDAFDMLDEIEF"
     gene            32810..33676
                     /locus_tag="IXT46_000826"
     CDS             32810..33676
                     /locus_tag="IXT46_000826"
                     /inference="COORDINATES: protein motif:HMM:NF028182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946762.1"
                     /translation="MRIKGKNISWVFYMLGILAFTFVAIKLSEIIIPNDSVVSKNLVL
                     ERAKLIISILGPALTLIVFVRTIQTQLESSKNLIKDNVSKDFYNLLNLFKSIQDKMNS
                     ELFSTIEKRIKVPINNINTNLDVRENKETTKEVQEDLKEYSASLNKVLSESVKKINEI
                     FEDNYKDIGSYLKVFHRILKILNNRYESKDISHEEYKMYVGILRSQIEDYEFYIILIN
                     SLFTLRGTGMGIELIETSFFGDELDIDLKQHFEHPEFLTEIIKDNFVEKKSYRESVKT
                     RKKIENYLKIER"
     gene            33805..34977
                     /locus_tag="IXT46_000827"
     CDS             33805..34977
                     /locus_tag="IXT46_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAQ4946763.1"
                     /translation="MSLFDIFKQSIKNEDPSDWIPDFVFGDEESARAYLKIMAKSTVL
                     DFVARTMSTLEVKFKNKDGTSDWDYILNVRPNSDMSAATFWQKFFYRLLDDNEVLVIF
                     TDDNQLLIADDFSRTEYAVYDDVFTNVMVKNFVFERSWAMSDVIYMEYNNEELERFTR
                     GLFEDYAELFGRILEVAMRNNQIRGSVSIDSTGTANDEKGKDGKTRSQRLQEYIDKIW
                     NSFKTNSVAIVPKVKGFEYEEYTNKQGVSNQSLDELNKMKSSLIADVANAIGVPTALI
                     YGEKAELDSNIKAFRKLCIAPLVKKLQDELVAKIISRQEYKNGERIEVKKVLQKDLLE
                     YATQIDKITSGGAFYIDEVRDEVDYDELPNNEGKIRIRTKNYEETVKGGENDNAES"
     gene            34964..35668
                     /locus_tag="IXT46_000828"
     CDS             34964..35668
                     /locus_tag="IXT46_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAQ4946764.1"
                     /translation="MPKAKKVPFQFTNEIQNGKHILTLSGNVQKKYWRDDDVINAKDI
                     RDSLDTVTDDIVIKLNSPGGDVFEGIEIYNYLKDHPSNITVEVTGLAASAATFIVAGA
                     NDVIMNVGTSLMIHEASTFAWGNKQDIQKTLNALETIDDSILAIYSDKTGQSVDKLRE
                     WMNEEKWFTADEAVKYGFANSVKREEPQNEPQNIAAMIQDAVAVAIANLKEPVTNKIE
                     QESKQKSLIARLRKGE"
     gene            35673..36833
                     /locus_tag="IXT46_000829"
     CDS             35673..36833
                     /locus_tag="IXT46_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAQ4946765.1"
                     /translation="MLKITDKTADAKKAFNAISSKEDATPEQINAALEEYVTAIAEDA
                     GKQVRAEYEELKNVTDNRVLEARGIPTLTVEETKFYNEAVKSGGFDSDVVWPETILER
                     VFENLQNDHPILGLINFTPTVGRVKVIRARRKGVAVFGPLHKDLEGQLDAEFGATEFV
                     QLALTAFFLISNDTLDLGPRWIDRFINLSLSEAVRDVWAKKIITGSGKDEPIGLLKDL
                     DGAVTSGVYPDKASAGTLTFAKEKIVLELAGVMKKLSKYTYKVDGDDEGEVEYRSVAG
                     RVYLIVNPVDYWDIVARVTFANLNNVYGTTMPFIAVDHIIESVDVPESKCIAYVDKEY
                     EATQSRAEKVYVYKETFAMKRATLYAVDMLGNGYPTNNDAAQVYDLDFTAGE"
     gene            36909..37187
                     /locus_tag="IXT46_000830"
     CDS             36909..37187
                     /locus_tag="IXT46_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAQ4946766.1"
                     /translation="MNTEEFIKEYKARFRIFHTSEDEDIGKQLESGFADIKSLIGSFD
                     PSTYEKGKELVYERTRYLRNESLEYFYDNFQTMIMDASIDLAGAGYAN"
     gene            37168..37539
                     /locus_tag="IXT46_000831"
     CDS             37168..37539
                     /locus_tag="IXT46_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HAQ4946767.1"
                     /translation="MLDMPIKSNYKKPKIVAGDLNTPVTFFEFQPNKGPEPGDEEKKE
                     LYFCTALVYNPSMKDRDILGTKEGVTIKIRDPHQSYIPTNKHKVRILDYRYGDKVWEI
                     IDVSPDLEENSIVKIVLELIT"
     gene            37555..37959
                     /locus_tag="IXT46_000832"
     CDS             37555..37959
                     /locus_tag="IXT46_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946768.1"
                     /translation="MSNVKFEGVQETIQALEKKFGEKKTKTLTKKAINVGAEKVEKQL
                     QTDMTVFKDKGYTIDEVVRKNATYRNYKAEAEIGWNGPHQRYRIIHLNEWGYTRKGKQ
                     IRPRGFGVITKSLKNSEPLYFDAVGEEVKKRL"
     gene            37956..38366
                     /locus_tag="IXT46_000833"
     CDS             37956..38366
                     /locus_tag="IXT46_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946769.1"
                     /translation="MKDMLNIIYEALCLNEYIRSMTYNENTEQYRIKFYEQPETADKT
                     GPMITLRPVDTPNEAYHGSNKELSVEHMVQIDVESKYRATCKQIQYEIKKEMKKLGFG
                     QISGQGLDEYFSETKRFVDARRYEGNTKIYDTEY"
     gene            38427..39014
                     /locus_tag="IXT46_000834"
     CDS             38427..39014
                     /locus_tag="IXT46_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4946770.1"
                     /translation="MTLVGFKKMTIGIFDSTGKIPAANLYVIEGEQDKGATVSAEISG
                     LSKEPSKVYGSNIAYYVSQKGTGDVSATFGLLDLPTEVNDKILGYKTDTNKISFLGED
                     TEPPYCAILMESEDLNGDTAMLAMFKGKFSRESINLNTTTNEAFEPEAEEYVFSAIAN
                     DVEGDAKGQTVAKYVGDEEASITALKEMVFPAAGE"
     gene            39087..39554
                     /locus_tag="IXT46_000835"
     CDS             39087..39554
                     /locus_tag="IXT46_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig domain-containing protein"
                     /protein_id="HAQ4946771.1"
                     /translation="MPDTFKIYKKNGTEFTKVAEGESPLSITGIAANTQVAKGDYQAT
                     RVVGGQESVKVDIPAFTTLPISVTGVTLDKTTAEVEQGGTLKLTPTVTPANATDKTGS
                     WSSSNTAVATVTGGNVTVKTDAEVGGTTEVSFTTTDGGKVAKCTITVIEKAAG"
     gene            39600..39908
                     /locus_tag="IXT46_000836"
     CDS             39600..39908
                     /locus_tag="IXT46_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946772.1"
                     /translation="MAKVRIELKEESGKKVYENIDTTGKDYRKALETIKKLNEDGVMI
                     WNRLDIYLDFAVGIFRDSKLTAEQILDGLPSEKVMSTLDDILGEVMGIESNPDPDAKK
                     "
     gene            40103..46867
                     /locus_tag="IXT46_000837"
     CDS             40103..46867
                     /locus_tag="IXT46_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAQ4946773.1"
                     /translation="MANGKPLGNMIIKLDLDSSAFSKGLAGAKNAVNHQMKAMKSQMQ
                     VMNSSGNSLGALQAKYNGLGGVLQANEKQVELLTKAYKDSFDSNGNATASTAKYANQL
                     NQATARSASYESQMKTTVGQIARMKVETEGITGKLKANSDVLINSGKKIEAFGKGVSG
                     IGSALTVGVTAPIVAGATAVTSAAISWESAFAGVKKTNDEVVDSNGNVVYSYSDLEKG
                     LRDLATKLPASHQEIANVAEAAGQLGIKTENVVSFTKTMIDMGESTNMSAETAATSLA
                     RFANITQMSQKDFDKLGSVIVDLGNNFATTESEITEMGLRLAGAGKQIGMSQGEILGF
                     ATALSSVGVEAEAGGSAFSKVMIQMQLAVEKGFGAFDQLKQMAEEQGVPWVNLVNAVR
                     DGGKSLKAVSEQMGFTSSDLKKMYKEADNSKSSLENFANVAGVTSEQFQKLFKSDPSE
                     AIIKFIQGLKDSEKHGTSAIKVLDDMDIKEVRLRDSLLRAANASDIFKGAIEKGNGAW
                     KQNTALTNEANKRYETTESKLKMLKNEVIDTAIDLGGPFVDALRDGLNVSKPLIKNLG
                     NMAKAFSAMSDDQQRNIIKWVGLAAAAGPALKLLGTGTSVIGKVTSTTGRLTKSLVDL
                     AAKAAEKKALDAFASSVTTAGAAAAKTAGAGGIGGLVPMMGKTASAASTAAGASGIGA
                     MTTSLGLLGPALLGIVGVGGALAVGYGAWKLFGEEAWNSSQRVKQWGTDVGEEIDNTL
                     DGVQKNIEGANGQFGLLKEGFTVDDANNMAANFATAGTSLETSLTGRIKALDDALKGL
                     PQSVQDAMKEVAESEEETLGQSLSKIKDNNEEIKKIRERAANQNRDLTVSELQQIQDL
                     MKGTSQAYVDTLDVSAKDRKKILSAMNGDVAQATEEEAKTWLQSLAKQKAATTENYRQ
                     MLEEKKAALKEKGVSKEFIDALEDEMNDYIKTTNQGFDSQIAAITNKYPQLINEVSLS
                     NGQLFSKTAAAMDNTGQYTKVFLESNEKILAQAKKTSDEIADNAEKNAEQLGMVADEA
                     THAGSTWNGLVLDEKTGKVKTNVQEVVNEATKDFTKWNELKPVVHDAKLTTNAKDVIS
                     IAAVQNGYWDDMEWKEKEALLEDECSKNVYKALENAGKWNELDIPSKEAILTSNTPEV
                     MGETLMNLGLWDTYKLQVKDLDLNAYKVYDAIDGSEEKLNSWAQLDNPTKELLLDNSD
                     FSTKLFNSEEMFKRWNQLSSNAKFLSANNTKFTEVLLSSDRMWNQWVNLPDNEKRLLA
                     DNEDLATTVLSSEEIYGRWTQLPDNQKYMLADNTDLANKIFASEESWNAWKAIPDIVK
                     NLLGNNIDLLAKVKDGTVSVEEYNKVMPLLKTLYGDNVNLKEAISGAKSSIENYNKNI
                     FPNDKTAVGHDEASQAAKDAFEAFNIFQTKIPDKITKTVSADFIGPMPNAKGTNFHPG
                     GAAMVNDQKGPTYEELITLPSGEAFIPKGRNVVLDLPRGSKVLNATKTKRLVPKYADG
                     IGNITTVSSTLNLDALILAINELTTVLRTQLMAETTNAKDTKLSDETKVADPIIPGSL
                     SEKSDQYLGIGAQWLTNLMNGWNSAVPQYMNSEMVFITNYLNALKLQNNPNYTQGVAW
                     NKNLLNGWNSLTGTFISTINSFCNQAMVTLRNYNTPMYNNGRTWQQNNLNGWNSLYGS
                     FIARVNQLGNDSINNLRSKSGGFYNAGTFLLQSLINGMNSLGNSLSTTMNNVANTMVG
                     GMGKGVNGVISGVNYVLKEVESSKNIGNWPIPQYAKGTDGHPGGLAMINDQKGLVHEE
                     YVQMPDGRGFIAKGRDLLVNLPKGAQVLNASLTKKLKERLNIPHYEKGIGNLDIVDLL
                     DDEKRMLEFLTSKVDFSGINEPWLDMTKSGTSLMSKAANTMLQSKLSEFFTHGNFDGA
                     VNANGVYQYLVDVAQKVMGKFPGLTVTSGYRAGDAYYHGKRQAIDLAYPGISGDPRYT
                     AAANYAFEKFPSKIAYVITNGRVRDRMGLSGTGSSGQWTNWPDGDHFDHIHLNGSMGS
                     GDIFNGGVGGSGVARWRSYVSKALKMNGLPATAAYINAWMSQIQTESGGNEKAIGGND
                     GLAEGNATGLLQTKPGTFAANAFPGHGNIMNGFDNMLAAINYAKKRYGVAGMLQVIGK
                     GHGYANGGLITKDGLYRAGEGNKPEMVIPLTRKTRAIELMGQALAFLSGDDKKRSNTT
                     NTADNSAELVTLIKQQQKQHNELMMILRAILGKDLSLKSSDIGQAANHYMGSDLNKLR
                     YTNGGV"
     gene            46871..47692
                     /locus_tag="IXT46_000838"
     CDS             46871..47692
                     /locus_tag="IXT46_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HAQ4946774.1"
                     /translation="MFYKLQFNQNGKLFDPQRKEKIVCKEIKRQAPVYEVNYEDFEGT
                     NGSREANASFRPFELVLTFDIFYKNKHDKELLLTEFYELIFVGYQYYISYDLSPGKRF
                     KVNPTNFEITEEENDYSTIEITFSIPSGSAESSATTLTDFNLEEEWQFSQGLVAEDYK
                     YTHQTSHFIIYNAGSFEIDPREHYLRIALEGESEGNVTIFNKTTGDRFIYYPSLSTNL
                     GQTLVLDGVIPKLNGVSCGINTNHGLINLVEGVNEIEIQNITRVKSSWDFRFLYK"
     gene            47701..48744
                     /locus_tag="IXT46_000839"
     CDS             47701..48744
                     /locus_tag="IXT46_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946775.1"
                     /translation="MTELIIRNYEQTKEEILVGYDKGSFYENWQQNETWEIGFTVTSN
                     SLNQEVFDLVEYESSVFYNGQEFVIKEMTRKALGQLLTKQVVATHIYYTVQDGYQYNT
                     VTGAKSISQLLTHVFSAGSRGFTWEVIDPNKKFLTVEQENFGNANYLKLINEILSDYN
                     AVVIPNNKHLTFYPASEYGQQTEEQIRYKYNTDEVSFDIDTYSLKTQIKGYGKLKDGA
                     NTENPKDSDYIFTPITYTSPESQKWGIRIQDPVKDERYTVSGNMLERLKTDLQDYPNI
                     SGSVTLKWKISPNKGDHVPFIYEPLNINTYIQVVGIKTYPAIPNKPPEITLSNTKKTM
                     TSILAEMAKKGVI"
     gene            48744..49775
                     /locus_tag="IXT46_000840"
     CDS             48744..49775
                     /locus_tag="IXT46_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946776.1"
                     /translation="MGLLKLISNRISTEWKEKFNKNIDYLNDLEKKLSDQDKSMNSRI
                     DNLVLHSGGESPNEVVDARVNNKGETFPTLHGRLVEHETLTDEQISELNTNMDSQKEQ
                     VQQLNKSVQQIIGGYNEPINIYVSKDGSDILGDGSEEKPFLTIQTAVNNVPLITTSQI
                     TIWVGSGAYLEDIMIRNLNFTSFLIRPIDNFDTIDPLKSDLPVKIRSICFTACKGYCQ
                     VAGMQIVDTANGADYGIRNEQSGYMAINRCKFAENTKTLARYNAVYVGGTSKINMYGD
                     TTLINQKVAIYAVLMGEIFVSAFGSGNDVGILCENGTVRGTVSTSFATTPTKTTGYGL
                     IITKGTVLQ"
     gene            49775..51877
                     /locus_tag="IXT46_000841"
     CDS             49775..51877
                     /locus_tag="IXT46_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HAQ4946777.1"
                     /translation="MVYKTNESIIMIQAEATSPNRTNVVFWSHDRGTAKLRMKLVRKN
                     GIPQSLPEGTTVPIRLMLKSATAEGGYGKHDYLATIEDRVNGIVSIVLEDNILGYVGI
                     VEGSVYIDFPNDRSLDTAGRFTFDIKRSPIDDSTPELEDYYFNGFSQTIDKIEKILAD
                     GKQEIEQKITESETQIDGKLKETSNKITKANQDVATINTNIDKANDRIDQTNQQISDL
                     GKLKKMYSNSIDFGNYDYSGNPNLMANINADSFSQGSGALSVVDDGDEVVITLDPNHK
                     LEIFKAKSQPALVVGKTYTMSVEIMLEDDFTGDPSNISLRYIKMPSWLTVLYTPYTLT
                     NTKGVWQKLTVTAKMTTAIDNAESWFIMLQNKDANNSLSGKLRLRHAKLEEGSTATPF
                     QPNLLAEPYNMCREYPNENIADPKVKFPIESGDHQIYQGYTEEELMIGQTYTITLKGT
                     KPASQTFVAYNHWTARLGELKPVDGLTDVWSLTFTPTNVVAMPKLFRVYQYPRSTVGA
                     CQIDWLKIEKGNTRTPNISQFKYFGEGLKDSNNPNDYSWDVTPEYTEKGLNNAVNVYD
                     PQRVEGLKNFADGIQIAGDKVISENDCTVYTLTKDNSQSFIDGYATFIKHGKEVVVNG
                     TVKFKKAYAFGVPLDDEVPDEFIARIVHGMLTGQSGTNSVSKAMYVQKDLGKIMTNSE
                     FAANEWFTFHGNYWVGVK"
     gene            51878..52324
                     /locus_tag="IXT46_000842"
     CDS             51878..52324
                     /locus_tag="IXT46_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946778.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGLRADGEPL
                     TIADQMFDPKLNQWIVLANTLDHNDLNNLKAMYEALEHENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPTLKGGE"
     gene            52326..52463
                     /locus_tag="IXT46_000843"
     CDS             52326..52463
                     /locus_tag="IXT46_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAQ4946779.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIISKEESA
                     S"
     gene            52498..52740
                     /locus_tag="IXT46_000844"
     CDS             52498..52740
                     /locus_tag="IXT46_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAQ4946780.1"
                     /translation="MKEEALQDVVERLVRIETKLDNYESLREKADSAKDLADKAYSVA
                     LNNAEDIKEMKNNNKWAWGYMIGLGITIIGYFLTKL"
     gene            52756..52953
                     /locus_tag="IXT46_000845"
     CDS             52756..52953
                     /locus_tag="IXT46_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAQ4946781.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASALVAMLGKAYGWNGTDMIVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            52964..53983
                     /locus_tag="IXT46_000846"
     CDS             52964..53983
                     /locus_tag="IXT46_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4946782.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQIA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
BASE COUNT        18730 a         8803 c        11231 g        15242 t
ORIGIN      
        1 cctttttttt tgctatatga caggaatgaa aggtgtttgc aagcttaatg tgaggaacac
       61 tttccatatc tgttctatac tggataggag aagtttggaa atatccagaa aacgaaatca
      121 atcgaggtag ccacatgaag aataaatgga taaatcgaag taaaaaaaag aaagtaacac
      181 aaagatcatc agataaagtc atccgtcttt ttccatcgta taaagaagga ttaacggcag
      241 atcaagtcaa ggaacgaata gaaaaaggtg cagcaaataa ttcagtcgat cccacattca
      301 aaacaaatca gcaaatcgta ttggaaaaca tatttacgta tttcaatttg atctttctta
      361 tcttagccat tttgctttgt ttagtagaat cctataagaa cttgactttt ttaccagtta
      421 tcatagccaa tacaggaatc gccatttttc aggaaattcg atccaaaaag atcttggacg
      481 aactaaatgt tttaaataca gcaaaagtca atgtcatacg agacgggata gaacaaacaa
      541 tagatataga agaccttgta atagatgaca ttgttatttt agagactgga tatcaaattc
      601 cagcagatgc agaggtcgtg gaagggaaac tgcaagttaa tgaggcttta ttgacaggcg
      661 aagcagatga aataaccaaa gaaataggtg atccattaat gtccggcagt ttcattgttt
      721 ccggaaaagc ttacgcccga ttagacaaag ttggagcaga ttcgtatatt tcccagctga
      781 cagtcaaagc caagacaatg ggagaaggag aacagtcgga gatgattgct tctcttaatc
      841 aattgatcaa atggattggg atcatcatta ttcctatcgg tatcctgctt ttttctcaaa
      901 gttacttttt taatggaaac acgatcaaag aaagtgtcgt tgcaatggaa gcagcattga
      961 tcggtatgat acctgaagga ctgtacttgc tgacgacgat tgcattagca ttaagtgcga
     1021 ctaaactagc aaagcaaaga gttcttttac acaatatgaa aagcattgag acattggcaa
     1081 gggtaaatgt cctttgtgta gataaaacag gaacgatcac agaaaataaa atgtctgttc
     1141 aaaaaatgat cgtctctaaa aaacaagaaa taatcagtca gtcagatcaa ttggaagcat
     1201 gcattgctga ctatgcaaaa gcgatggcag gagacaatgc aacaatggaa gctgttaaag
     1261 catattttac aaaaaccact gatcaatcct atcaccatgt tattcctttt tcttctgtcc
     1321 aaaaattcag cagtgtagcg ttggcagaca aggtgtatgt tttaggagcg cccgaaatgg
     1381 ttttgcgcga tcaattgccg gaatatgcgg aagagtttgt ttctttcgct gaaaaaggct
     1441 atcgcgtgtt ggtctttggt gtgtacgatg ggattcttga agaaccagta ttgacagaag
     1501 cagtcacacc attaggctat attctgattg ctaatcctat cagaaaagaa gcaagagcca
     1561 catttgatta cttcaaaaaa cagcaagtag ccatcaaagt gatttctgga gataatccgc
     1621 tcaccgtatc caatgtagct gtccaagcag ggatttcaca tgctgatcag tacgttgatg
     1681 catctaaatt atcagaagaa gaatatgaag cagctgtcga aaaatataca gtttttggac
     1741 gcgtcaagcc agaacaaaag aaaatcttcg ttcaattgat aaagcgtaac aatacagtag
     1801 ctatgacagg tgatggcgtg aatgatattc tagccatgaa agaagcagac tgcagtatag
     1861 cgatggcttc cggaaatgaa gccgccatgc aggcctcaca agtggtctta cttgattctg
     1921 acttttcacg catgccagaa gttgttgcag aaggacggcg cgttgtgaac aatattgagc
     1981 gatcagccag cttgttttta gtgaagaata ttttctcctt tttgctctca ctgttttcag
     2041 tgatctttgc tctgacctat cctttagaac catcacaaat cacattgatt agtttgttta
     2101 ctatcggact tccatctttc ttgcttgctc tagaagaaaa caaaaagcga atcagaggga
     2161 aattcatcat gaatgtgatg gaaaaagctg tgccaggtgg actaacagat atgatcgtag
     2221 tcggtgcgtt ggtgatctgc ggggtgactt tgaatctaaa taaaacagat gtttctacag
     2281 catctaccat gcttttgatt gcagtagggt tcctcgttct ctataaaatc tgttcaccgc
     2341 tgaataaatt cagaagtcag atcattcttt tctgtgctag cggtaacttt ttttcggtca
     2401 tctttttgca taagctgttt tcaatcaccg gtatctcagc tgtatcactt ttgctgttga
     2461 gcattctatt tttctcggca gattcgattt ttaggcattt gaccacattg gtagaatatt
     2521 tgtttgaacg taaaaatgaa aaagagcaaa agccgtttag tcgcgtagct aaaaaatttc
     2581 tatcgatatt taaacgagaa aattgacgaa aagtatctca aaaaagagta aaaaagaaca
     2641 accactcgtg tatctttcga agcaggatga gtcatccaac tttaaaacgc acgagcagtt
     2701 gctctttttt acattttcgg aatggtaacg gtgaaagtcg aacctgttcc aagatgactg
     2761 tctacagtaa tcgtaccatt aaggagttgc acgtagtctt ttacaatcgc taaccctaat
     2821 ccggtcccgc ctgaatgtcg gcttcgcgcc ttgtctacgc ggtaaaaacg ctcaaagatc
     2881 cgttcctgat cctcaatgtc gatacctata ccaaagtctt ggacagaaaa cgatagatca
     2941 tctgttgcct gatagcggat aataatctcg ctgtcgcttt ttgaatattg gacagcattt
     3001 tcaatcagat ttttgataat tggataaagg atatctgttt tagtagtaaa tggttcgttc
     3061 tttccaatca atcgaatcgt caaccgtttc ttttcgatga ttggctgata attttgaacg
     3121 atttgctgga aataaggttc tgtataaatt gtctggatct cgtaagaatt ctcgccatct
     3181 tttgacagct ggatgatttc ccgaatcagt ttatctaacc ggatcgcatc tttttgcatg
     3241 atctcaagaa aagaagtcag agtttgcggg tcatcttttg caccatccag taaagtctcg
     3301 gtaaaaccaa tcagtgaagt cacaggagtt tttaattcgt gagagacgtt gccaacgaaa
     3361 tccttttgta gcttttctaa acgtcgcact ttcgttaagt catacgccac ccctagaatc
     3421 tgtccggtac cttctgaatt agtaaagtag cgcaaactca agtctaatgt ctgccgacct
     3481 tctgtaaggg tgatctcctg atggatcagc ggatgctcag gagtcacttg atgaatcagc
     3541 tgaatgagtt ttggctcttg aatgacttct gtgtaccgct gttcaggttg atagcttacc
     3601 acgtttaaat gtagctgcat ctttggatta agcagtagta aacgagaatc agcatcatca
     3661 atcaggaata cgccaatcat cagttcgttc agtaacgtat ataattgctc ttctgtggta
     3721 gtacacgccc gatacatctt actcatttgt tcgctcaacg cattaatcgt ctgatacaat
     3781 tcttcccatt gatcgggtgt ttgcatgatt acttccgcct gattaggatt ttgcaccatt
     3841 ttttttagta cgggcagcac ggttttcaat ggctggtttt tttgatagat cagataatag
     3901 atcattcctg caagaacaag gaagaaagac agaaagaaga aaaagaccca acggcgaaaa
     3961 ctctcagttc tcggtaaaaa aacgcttgtc ggttctgcga tacgtaaaat ggcttctaac
     4021 tggccacttt ttttgactgg taatgcgaca tataaaagat cctcattcaa agtagtactt
     4081 ttgcgcaaag cgctacctag gttcccacca ttcaatacgg ctttgatttc gggacgggag
     4141 tttcgctgtt cattcaatgt ttcattgttt gtgtcaaata agatctttcc agtagcatcc
     4201 attaaagtaa tccgttcgtt cgactgatgg acgaattctt ccaaagcagt tttgttttgc
     4261 gctgcttgga ggttttcgac atctaattgc cggatcagca gttgtgcttt ttttgtcagg
     4321 tagctttctt gctgttccac gatctgctgt tgaaaataat gggaaatcaa ttgccagcca
     4381 ccaaaaaaca aactaactaa aagaataaga aagaagagac gttcataaat ttttttccat
     4441 ttcatcgttt gggttcctga aacttatagc caaatcctct aatagtcacc aagtactttg
     4501 ggtgttttgg atctcgctcg attttttctc gcaaatgact aacgtgtaca tctacgattc
     4561 ggctttgtcc tgcgaagtca aaattccaaa tgcggtctag caatgtgtct cggtcgatca
     4621 cacggtcttt tcgtttcatg aaataaacaa gtaattcaaa ttctttcggt gttagttcaa
     4681 tcagatggtc gtctacggtc acttgataat tggtcaaatc agcagtgatt tgtccaatcg
     4741 atagatattc aggctcagct tcatcttttg attgcttacg aggttcaatt cgtctgaata
     4801 ttgctttcat acgggctaat acttcgcgag gactaaatgg tttggtcaaa tagtcgtcag
     4861 cacctatttc taggccaatg atccgatcca cttggtcatc tttagccgtc agcatcaaaa
     4921 tcggtgtttc atttttttct tgacgcagcc gctgagtgat ctccatgcca tccatcgttg
     4981 gaagcatcac atctaaaatg atgaaatcaa atgattgttc taatgctaat tctaatcctt
     5041 cgcctccatc tgtggcactg gttaccttgt agccttcttt ttccaaattg aacgtcaaga
     5101 gcgttacaat agaaggttca tcatcaacaa ctagtatttt tttcattcaa atctccttta
     5161 aataggtttc attctgttta tattttagca tagaatcagt acaaagggct attttacaaa
     5221 agaaataaat ggtataatag gaaggcactt tgctgaatag aaaggaagag cagtcaatga
     5281 ttggaatcag tgcatgttta ggcggtctgg cctgtcgcta tgatggacag aaaaaagaag
     5341 taccagaatt gatggaacta gttgaaactg gagaagctgt catggtctgt ccagaagtga
     5401 tcggcggatt accaattcct agagatcccg ctgaaatcat tggtggaaat ggattcgatg
     5461 tgtggaaaga tcaagcaaaa gtatggacga caagcggcga agatgtaacg gaagcgtaca
     5521 aaaatggcgc gatcaaagcc tatcaaaaat tgcaggaaaa acacattgat ctagtcatca
     5581 tgaaggaaaa aagcccttca tgcggaaccc attcgattta tgacggaagt ttttccggaa
     5641 taaaaaaaaa tggtgccgga gtggctactg cttattttat tcagcaaaaa atgactgtgc
     5701 tctctgatga agaatggctg aaaactagag gtgagcagaa tggaaatcga aaagaccaat
     5761 cgaatgaacg cgctctttga attttattcg accttattga cagaaaaaca aatgaactac
     5821 atggaattat attatgcaga tgatttttca ttaggtgaga tcgcggaaga atacgaagta
     5881 agccgacaag cagtatatga caatatcaag cggacaagca agatcttgga ggattatgaa
     5941 aaaaaactcc atcttttttc taattatatt gttcgagaac aggtattgga aaatatgact
     6001 gcatatatta cagataagta cccggaagat aaaaaactac ttgaatatgt acagcaaatt
     6061 caagcaatcg aagaataaat aaaaggaatg aagaaaatat ggcatttgaa agcttaactg
     6121 aacgtctcca gcaggcgatg ggaaaaataa gaaaaaaagg aaaagtatca gaagctgacg
     6181 taaaagaaat gatgcgggaa atccgccttg ccttactaga agccgatgtt aacttgcaag
     6241 tagtcaaaga ttttactaag cgcgtacgcg aacgtgcggt aggggcagaa gtgctggaaa
     6301 gtttatcacc tgcacaacaa atcgtaaaaa tcgttgatga agaattgacg atcacacttg
     6361 gttctgaaac agcagagtta aataaatcac caaaaatacc aactgttatc atgatggctg
     6421 gtcttcaagg ggcaggtaaa acgaccttta ctggtaaatt agccaattat ttaaagaaaa
     6481 atgaaaatgc tcgtccgctc ctaatcgcag gggacgtata tcgaccagct gcgatcgacc
     6541 aattgaaagt attaggtcaa cagctagacg ttcctgtatt tgatatggga actgaagtca
     6601 gcccggtaga gatcgtccgt caagggatgg agttagcaaa agaaaagaaa aacgactatg
     6661 tattgatcga tacggcagga cgtctgcata tcgatgaaac attgatggat gagttgaaac
     6721 aaatcaaaga attgacgcaa ccaaatgaga ttttgcttgt tgtcgatgcc atgactggtc
     6781 aagatgccgt caacgtagct gatagcttca accagcaatt aggtattaca ggggtcgtca
     6841 tcactaaact tgatggggat actcgaggcg gggcagcact atcgatccgc tcagtgacag
     6901 gcgcaccaat caaattcatc ggttctggtg aaaaattgac tgacttagaa gtattccacc
     6961 cagatcgtat ggctagccgt atccttggta tgggggatat gctgacattg attgaaaaag
     7021 cgcagcaaga ctacgacgag aaaaaagcgg aagaacttgc acagaaaatg cgggaaaatt
     7081 cattcgattt caatgacttt attgaacagc ttgatcaagt gatgggtatg ggcccactgg
     7141 aagatctaat caaaatgatc ccaggaatga atcaagtccc tggaatcgaa aacgtcaagg
     7201 tagatccaaa agatgttgaa cgcaaaaaag cgatggttta ttctatgacg ccagcagaaa
     7261 gagcaaatcc tgatctgttg aacccaagcc gtcgtcgccg aattgctgcc ggttctggaa
     7321 acagtgttgt tgaagtgaat cgaatgatca aacaattcaa ggaatcaaga aaaatgatgc
     7381 agcaaatgtc caaaggggat atgaacatcc caggtatgga ccaaatgttt ggttcaggcg
     7441 tcaaaggaaa actaggcaaa atggcgatga atcgaatgat caagaaaaat aagaagaaaa
     7501 agaaaaaacg gaaataagat gaaaaaaaca gcttcggtac agactgaaaa tgtctactgc
     7561 cggagctttt ctatcagcaa tttttattct ttactaatac aattactcta aacgaagagg
     7621 tggcacagat gagatgtccg tggagtgaac aaacagaaag tatgcggcaa tatcatgata
     7681 ctgtctgggg tgttcctgaa tatgatgacc aaaagctgtt ccgaaaattg atgcttgata
     7741 ttaatcaagc cggattgagc tggcagacga ttttaaataa aagtgaagca ttcgatgaag
     7801 catatgatcg attcgatatc aaaaaagtcg caaattatgg agaaacaaaa atcagtgaac
     7861 taatggaaaa caaaggaatt attcgtaacc gaagaaaaat cgaagcagcc gtccaaaacg
     7921 ccaaagcagt cttgaaaatt caagaagaaa tcggcagttt ttcagagtat ctttggtcgt
     7981 tttctaatgg aaaaatcgtt gattcttctt atcattcaca agaagaagtc ccaacaacaa
     8041 gtcctctttc agatgaatta gcaaaagatc taaagaaaag aggatttaaa tttatcggaa
     8101 gcacaacaat ctatgctttt ttagaagctg tcgggatcat caatgatcac cttgacagtt
     8161 gtttccgcaa agaagaggtc gtacgtatcg gcagaaaggg cgaataaagc atgcgaaaaa
     8221 tcatatttta tggtgctata agtttagatg gctatttggc aacgaaaacg gatgatcttc
     8281 aatggctttt tgacactcca acaggtaagc aaactactta tgaagctttt tatgaaacaa
     8341 tcgatacgac catcatgggc agaaaaactt atcaggaagc aaaaaaatat ttggagaccg
     8401 aagcaattta tccagagaaa aagaatttcg ttttttccac ccacgcacaa ttacaattgc
     8461 cagatgctga ggtcgtaaac gaagatcctg ttgcttttct aaaaaatcta caaatgacag
     8521 aaggaaaaga tatctgggtt gtgggtggcg gtcgattgat caaaccgcta ttggaacatc
     8581 aaatgattga tgaatggtat atccagatta cccctgtatt attaggggac gggattcctt
     8641 tattccaaaa aggaacatat gaagcgcgtt ttgaaatgct agacacgaca cgattcggtg
     8701 aatttatcga attgcattat gtacgaaagt agaagtaaat aaaataaaaa aggcaactat
     8761 atgcagaaat gtcctgtaca tagttgcctt ttttattacc gttatgcttt ttactctgtt
     8821 aatttgttag aaaaatctag atacgcatct aaaatcgttt ggaagaaact taatgttcct
     8881 tcaacgatat taccattttc atcaattaga ttcgcaacgt ttccgatata tgcttccggt
     8941 tgctgcaagg ttggcacatt caaaaagaca agtgattggc gtagatggtg gtttgcgcca
     9001 aagccgccga tcccacctgg tgatgcagta acgactaaac ctggtttatg atcccaaaca
     9061 ctgtgtccat aaggtcttga gcctacatct aaagcatttt tcaatactgc tggcacagaa
     9121 cggttgtatt caggagtaac gaaaacgaca ccgtctagtc ccctcacttc ctcacgaaaa
     9181 cgagtccatt cagcaggagc ctgttctgga gtttcgagat cctcattgta aaatggcaga
     9241 tcatcgattt ttacaaatac actttcgtac ccttcaggaa gcaatttcgc aaaagcttct
     9301 gctacttttt tgttgtaaga atcttttctt aaactaccaa taaaaaatcc aatttttttt
     9361 gtcatacgat ttttcctcct tcaaactatc tataataatc ttacaaaaga taagtaactg
     9421 gagcaaataa aaacacttac tgacaaaagc tacatagaag atagattact tatttttaac
     9481 aaaaaagaag tctaaaatct tctattttct aaaaaaaatc gaatttaatc aagctgtaaa
     9541 gaaaaaaagc tttacagggt aaaaaaaaac tgttacacta catcttgtga ataaaacaat
     9601 ggaggtggaa ataaataatg gcagttaaaa tccgtttaaa acgtatgggt tctaaaaaga
     9661 gtccgtttta ccgtatcgtc gtagctgatt cacgttctcc tcgtgatgga cgtttcatcg
     9721 aaactgtagg tacttacaat cctttgaaag accctgcaga agtagtttta aaagaagact
     9781 tagttcttga ctggttatca aaaggtgcac aaccttctga cactgtacgt aacatccttt
     9841 caaaagaagg cgttatgcaa aaacaccacg aagctaaatt ctcaaagaaa taaggtgacc
     9901 ggatatgaaa gatttaagcg acttagtctt aacaatcgtt cgtccgctag tcacttatcc
     9961 tgatcaagtc aagttagacg tcgtagagtc gaaagacttt tacgagtaca atctaacagt
    10021 ggctcctgaa gatattggcc gtatcattgg aaaacaaggg cgtgttgcta aagcaatccg
    10081 cacaatcgtt tacggtgttc ggatcaatgc accgaaaaaa gtgcgtttga atatcatcga
    10141 tgataaggaa aagtaaataa acgtgctgta ctcgaatttt cgagtgcagc ttttttgttt
    10201 tttttattaa ttgaagaaat gattatttgg caaaacaagc aagaaagcgt atccttatag
    10261 gaggagggag tgaacagcca atgagaaaga aaatgttatt tattccattt gctctattgt
    10321 taagcgattg tagttcggtt actcaagaat cagacaatac acatctatca agcagtatat
    10381 ctgaaactgt taccagtcca gaaaaaagta gtaccaaaac ggcttccacc actgaacaaa
    10441 caatggctac ctcaaataat gagaaaaaga ctgctttaga ccagttgaaa gaacaacagc
    10501 caaatgttcc catgcctcta gatgtaccag tctcttcagg ctatctcaat atcgcagcga
    10561 cacatacaaa gcaaggttat tctattttat attacagaac agatcgtccc ctcgggttga
    10621 atgctgacga attgaatcaa gaaacgccta ttgcaaccta tctatatcaa tatgggtttg
    10681 cttctagtca agaaacaatc caagttttgc agccatttga gatcgacaca aatggtcagc
    10741 aagtggactt aggttctcga atcacagggt atcagcaagg tgcagcaggt tcaagttttc
    10801 ttgaatggca agaaggaaac tggcgtattc gaatccgtgg gaataatata gaaggccaag
    10861 atcccttact attagctaaa gaaatcgtag cttatttgga agaaaacagt ctaccagcac
    10921 ctgaacaatt tggtaaaatt actgttgata tgggtgatac gacgaatcga gccgtagaag
    10981 taagctggca agaaccgaaa aatgcctata cgatcactca tcaagatcct atgtctgcgt
    11041 tgaagatggc agtttctatg aagaggttgt gaaatcagcg cgctgatctg agcccatcat
    11101 ttaactccaa gtcacaggaa gtaatcaaaa atagcacgcc gcatttttgc ataattttgg
    11161 cttaatacct taaaagaaaa ctagaattgc ctcttcacac atgctaaaat aaaacagaca
    11221 aaaaagaaat ggggatataa gttgactgaa tacttgaatg taggaaaaat cgtaaacaca
    11281 caaggtatca aaggcgaagt ccgtgttatc tcaacaacgg atttcccaga agaacgttac
    11341 aaaaaaggaa cggtgctaac actattccaa gacggaaaag cacctgtgga attaacagtc
    11401 aaaagtcatc gcaaacataa aaattttgac ttattgagtt ttgaaggaca tccttctatc
    11461 aatgatgtgg aaaaatatcg ggatggcata ttaaaagtgt caaaagacaa ctctgtagat
    11521 ctagctgaaa atgaattcta ttaccatgag atcatcggtc tgcatgtatt agaagatgga
    11581 actgagttag gtaaagtaaa agaaatcttg tcaccaggtg ccaatgatgt ttgggtcgtt
    11641 caacgtccga aaaaagctga tatattgctt ccatatatcg cttctgtcgt caaagaagtc
    11701 gatttagaag ctggagtggt ccgtgtagaa attccagaag gactgattga cgatgaagat
    11761 tgatgtattg actttatttc caagaatgtt tgaaggtcct atgggggaat ccatcatcgg
    11821 taaggctgta gataaaggat tattagatat caatatctct aacttccgcg attattcaga
    11881 taacaaacat cagacagtag atgattatcc atacggcggt ggagcaggta tgctgctcaa
    11941 agtccagccc atctatgata acatccaagc cattgaaaaa gctgcaccgg atgtcaaaaa
    12001 aagagtaatt cttcttgacc cagctggtaa acgattcgat cagaaaatgg cagaagaatt
    12061 ttcacaagaa gaacacttag tattcatttg tggtcattat gagggatatg atgaacgtat
    12121 ccgcacatta gtgacagatg aagtttcctt aggagattat gtccttactg ggggagaatt
    12181 aggtgcgatg gtcatgatcg atgcaacagt tcggcttttg ccagatgtgt tagggaatca
    12241 gacttcagct caaacggatt cttattcaac cggtttattg gaacatcccc aatatactcg
    12301 cccggcagaa tataaaggga tgaaagtacc agaagtattg acaaatggaa atcataaatt
    12361 gattgaagaa tggcaattaa aagaatcact aagaaggacc tatcaacgtc ggcctgatct
    12421 tttggaaaca cttgaatgga cacctcaaat gacgaaattt ttagaagaaa tcaagaaaga
    12481 agaacaagaa aaaacagcag atgaagccaa gtgacttttt ctaaaatctt ctttacagta
    12541 ggttgataat atgttagtat tttatggtga gtgcaaaagc acttaactat tacgatattc
    12601 cgctgtgaga aaagctcata agaatatttg gaataaggag aagaaaacca tgaatccatt
    12661 aatcgaagaa ttaacaaaag aacaattacg ttctgacatc ccagcgttcc gccctggtga
    12721 cactgtgcgt gttcacgcaa aagttgttga aggtactcgt gaacgtatcc agttatttga
    12781 aggtgttgtt atcaaacgcc gcggtgctgg aatcagcgaa acttatacag tacgtaaagt
    12841 ttctaacgga gtgggcgttg aacgtacatt cccattgcat acaccacgtg ttgcaaaaat
    12901 cgaagtagtt cgctacggta aagtacgtcg tgcaaaattg tactacctac gtgcattaca
    12961 cggaaaagct gctcgtatca aagaaatccg tcgttaatca ttgttatcag actgagaaag
    13021 aacccttggt attcaagggt tcttttttta ttatctgttt ttttatatta acgatttcta
    13081 tttggtacat ttttgattaa taaaaagggg caaaaaaggg gcaacaagtt acagtttttc
    13141 tatatcttct ttcaattttt cttttactcc ttttgtcaca tgcaaataaa tcttttcagt
    13201 gatatcacta ttttcgtgcc caacgcgatc ctgaatagca tacagaggag ttcctagttc
    13261 cgctaatttt gaaatatggg tatgtctaaa aatatgtgaa ctaagttttt tatcaatctt
    13321 catgtcagct ttatgatttc tcaaataggt gttaattgct gttagttgga aaggagttcc
    13381 tttcgttgtt tgaaatagaa attgaccctt cggatttaat tctagaagct cattgtaaat
    13441 agctatcgct ttttttggta aatcaatttc tcgcattcca gcagcagttt ttgtagaatc
    13501 agattttttc atatcagcta ttgaacgttc tctatacatc atcgtcccat ttataactac
    13561 tgatgcatta ttattggtaa tgtgtacatc gtctttactt aatgcgattg cttctccagg
    13621 tctcattcca gtcaaatata gccactggaa aaggagagaa tatcttttat tgtgtgaagt
    13681 tgtgaaatct actagtcttt tatattcatc atcttctaaa aacttatctt taatttttat
    13741 cgtttttgac tctcgtttat aatcaataac tacttcgttg ataggatttt tttctacata
    13801 gccttttttc atagcgtatg aaaaaagaag attcaatttg gatttaatta cactgacgta
    13861 cttatttgac aagtcatctt tatatatcat atcttcaaaa atattattta aatctactgt
    13921 attaatacca gaaacgatgt aagtctcagg catcttcttc tttatagtgt ttaagatatt
    13981 attcgtagga taatatgtag actccttaac ttgccttttg taaataacta accattcttc
    14041 gacaagctca tgaaatgtta gattaggctt ctggagtgtt ttttcattta gttttatatc
    14101 aattttttta tttaactcca gtaatgccac tttctgagtt tctcgagact tatttttata
    14161 agtaatgctc actttttttc tttttctagt ttttggatca atatatcgtt cattatattt
    14221 atatactttt tttccgtttt tatcagtttt ggtttcaatc cacattgttt tcatctccta
    14281 tttgttgcta taataggaat ggataagtaa gccgattata gcaggtttat ttttcatcac
    14341 gtccacaaac tttggcgagg gagggggcgt gtttttgtat tttaacgatt tatattgaat
    14401 gttgattcag cactttcagc aactgtacta taatcagacg gattatataa cactccggtt
    14461 tttatcgtta cttttgtaat atcgttaact ttagatggat ctaagtaagc taaactataa
    14521 aattctttac tttcagtttt tttgaaaaac gagtttgttg tcattgtatg cataagatcg
    14581 tctgaactga aatcaatttg ttggccgtta tcaagtatgg cgtgtgcaag cccattataa
    14641 ccataatcta cttcagaatt gtttttaact ttgaatgcaa tttgtaaacc ataaaaattt
    14701 ccttcactat ctttgtgatt atttgcatcg tagtaaccag cagcgctagg gtcagcataa
    14761 ttggaatact tgagtagttt gatattagat atataaatgc cgatatcacc aagaggaata
    14821 tctgattgtg ggcttgccgt tccaattaat tcaattttgc cacttgtatc tcttttttct
    14881 ttggtccatt gaccaacttt gaggaggggg ccatcaacct cctgtgaatt tttagaagac
    14941 tgtgttgtac tttctgataa cgtaactgaa gagtcttttt cgtttgtttt gccagtatta
    15001 tctacaacat tagattggct acatccggta agaaaaaaag caccaaatac taaccctaaa
    15061 atcacttttt tcattcttta ttctccgttt ctatgatatt atttttatgt aggatcttag
    15121 aaacgagatc ttagtccgtg ttgcagcacg ggcttttttc tttataactt ttttagagat
    15181 tataggcaaa atagtaggac acaaaaatat attattgtat tccgtattta gaaaatccta
    15241 attgaacttc accagaagtt ttttgctgtg ttgtacgcaa tgcttcttct tcagacattc
    15301 cattctgtac tttccatgca acaggcgaca tcccgtattt gttaacaaaa tcagtaagtg
    15361 ataaagtgtc agcgtcttgc tgaccgcttg tttgttggtc ttctggattt tgttgagatg
    15421 ctgcttgttg ttctttctga tcttgactga taatattgcc agcatcatct gtagtcaatc
    15481 cattttcata aagggccacg ccgaaagctt cccactcttt gttggaccaa tttgcacgat
    15541 cagctggagt tgactgtaaa gtgcgttgtt tcatctgttc atatgtttct tcttgaggtg
    15601 cggtttggat tgtatcctga ctggagctta taactgttgg gctaggttcc gccgtagctt
    15661 ggttagagct tgtaactgtt gaactagaat ctgtcttaga tgtagatttg ctagtagagg
    15721 aactggtttc agttgtttct tttgttttac ttacttttgt ttcttggtta gaagtggcat
    15781 ctgttgattc agctttttta ttatttgaac aagctgaaag tagcagagca gtacttaaca
    15841 acaacataac gctaactttt ttcattttat aattcctctt tctcgttgta atatgtgtgc
    15901 taacacgggc ttttttatat aagaaaacga taagcgcttt ctggaagtcc gtaaagattc
    15961 tttaattcat cgattttttt gggatattga tcattatctt ctttataaag agaaacaatg
    16021 agattagcag caaagcaatt agcttcgctt tcagatttgc ttctagatgt tcttgttgat
    16081 acatagtaac tggataagcc gcgatgaaaa atagcgtgac ctaattcgtg agcgcaaatg
    16141 tagaatcttt cctcagagtc tcgcagttca tcatttaaga agattattgc acgacctcta
    16201 atttcttgaa actgtccttt gggattttcg ataaaaggaa cgtattgaat tttaatgccc
    16261 atcttttcac aaatataaaa aggattagca gaccggtatt tccgcttcaa ctcctcgact
    16321 aaattaatcg tatccatctc cataagctca catctttttg cctttttctt tgtcttcttt
    16381 cacaatatcc cagaaggttc caataaggat atcttttacg cgttggacct gttcaggcgt
    16441 cagtgtttct ccgccataag acatattgac atttgaatct agtaatttat caagttcaac
    16501 tacttcatct tttgttgccc agtcaggaac ttggtttcta ccgagtaaat aatcagtagt
    16561 tacattaaaa taatctgcta caagttgtag tcttttagta ctaggagttc tatttttcca
    16621 ttgataaatc gtgtttttag gtatatttaa ttcttcttcc aattgagtta tacttatgcc
    16681 tcttttatga gctaattcct ttattctatc tagtaaattc attttcgcac ctcacaagct
    16741 acgaaaacac taataaaaaa attagttaaa ggtgttgaca actaataaaa ttgttagtat
    16801 actgttttcg taagctaaaa tattagctaa aaagacttga taactaataa acacttcacg
    16861 gtcggcaaac tctgaaatgt aaattactag gcatttctgt gtcttattta gctatatcta
    16921 tatactaata aaaatattag ttattgtcaa cgaatattag ctaatttttt agcttacaga
    16981 ctatttttta gaaaggagct atttttatgt ctgagaattt agacttaaaa attcgagcgg
    17041 agatgagaaa aagaagaatg actttcaaag aactagctgc gcttgttggt atttcaggag
    17101 cttatttatc agatattcta aacggcaatc gtgatggaaa gaaagcacaa cagcatatcg
    17161 aaacagtgaa aaaaatattg gacatccgat agggggggta ggcgatgaca aaactaaaaa
    17221 aacaagattt tgtaaaaaaa tacaattatt ctccatctac ttatcaacgt cgaatgtcgg
    17281 aactaaaaaa tacagcaatt ttctcagcgg cgtatgaacg ggtcacagga caagaagttt
    17341 ggatcaatac agaattatac gataaatttt tgtctttcaa atcctataac aggttacgca
    17401 caagaaagat aacacctaaa gaatttatcg agaagcattt agttgattta taaaaaacag
    17461 aacattttga gaggtgaagg ttaatgggca aattcaacag agcactagta ttcagcacac
    17521 cattcatcat ctacgcttta ggcctctggg gaagcaggca agcgttgata ggaacgattg
    17581 tttacatggt ttggattttt atggggcttg atgaagctga agctgagtac agagcgaaaa
    17641 agccaaccga gggggctgac taaaaatgaa tagaaaagag aaactagaat gtatattact
    17701 attactcagt ttaattcttt cactaatttc tctattggga agtttgtatt tttgatatca
    17761 acaattttgt ggatttgggt tctatttaga gtaaatatca tttttgtttg gtgattaagg
    17821 agtttattaa aattaatttt ccctacttca aatgcaaggt aacaagatat agcactttta
    17881 ggaggaatat ttagcggtac agcttcagag tatattctat tatcatcgac tgatcctcct
    17941 ttagcaatta atttcttaaa tggagtagct gaccatctgc ggtttaagtt agcggatgaa
    18001 agttctaaat taactaacat agctggttct gttgaatagt tagaaatgat tacttttgta
    18061 taaatcatat ctgcagcgaa gtaagaagca ttaagttcaa cttctagttg agggcgcatt
    18121 ccttttattt ttatccctgt taaaaacgta ctcaatataa aacttattat tgacatccat
    18181 tgaaaaattg ttaagtgaaa aaaattcaaa ataaacacca ccagttttta actaaattat
    18241 accaaaaagg agagaagaaa taatgcaaga attagtaatt ttgaaaaata aagaagctgt
    18301 gactacgagc ttacaagtgg cagaaagctt cgagaaaaaa catcaacatg ttttaagaga
    18361 tattgatgca ctaaaaaaag atgtgtccaa ttttggacag atgtttgtag aaggtaatga
    18421 accagattca tatggcagaa atcgacgagt tttcttcatt agtagagatg gatttttctt
    18481 gctggctatg gggtttacag gaaagaaagc tatctacttc aaacaaaaat acattgaagc
    18541 attcaacgaa atggaagatg ttattcgcaa gaatactgtt cctcaaacaa ttgaagatat
    18601 gatgatctat caattagaag aaatgaaaga tgttaaaaaa gatgtttcca tgcttaaaga
    18661 tactatgcga attagcggac aacaagagtt tgaaattaag caaaaaggaa atatgaaagt
    18721 tatgggagtt ctagggggaa aagaaagccg agcttatgaa gaaatcagca aaaaagtatt
    18781 ctcaaaattt tggtctgaat ttaaacgtac cttttcaatc ccaagatatg gcgagttacc
    18841 tcgtaagaga ttcgatgatg ctgtttcatt tattgaaatg tggttgccag aaactgcgat
    18901 ccgtatggaa attgatcaac tgaacagaca acagagactt tttggtgatg acaatgaata
    18961 gagctgaagc gctaagaata gggacggcaa ttgctaattg ctggtggaaa tactataaac
    19021 caatcatcct aagccaacaa catattgaca agcaaaaagc atggcaacaa ataaaaaagt
    19081 gactccgccg gcaagcaaag agtcacaaag aaaacacatc ataaggagat tttagcatat
    19141 ggaaaaagaa ctttccactc tagatcaata tttgattgat cctgattggg gcaagccgaa
    19201 aattgaggaa acaagtggtc gaaaaatcag acgaaatctt ttgacgaatg aagaactagc
    19261 ttgggatcaa gatgatttag gcaaccatgt aactatttgg gatcatgttt atcttatcca
    19321 tctatcgaag cattcgaata aacctgaata tatttacgtc atcgaagatg gcttgattga
    19381 tgcgctagaa gagtacgaca gagataactt gattgatatc tcttattacg gaccaggtaa
    19441 gaaatacatt gctgaaatgg aggcagaatt tgatgagtga aatcaaaggg acaacgaact
    19501 ttgaaaaact ttttagtcgt aagttaaata aaattctcaa gaaaaaagga aattttgatt
    19561 atttatcttg ggctcacgcg tgggagatta tgaaaaagaa tgatccacag gcaacggtaa
    19621 ctattaatga gtacaaacac tacagggttg tttctggaac tcatcaagac tttcttgttg
    19681 aggaatataa accttttctt atggatgaaa ctgggactta tgtatctgtc tcagtaacgg
    19741 ttaaaggaca cacggaaacc gaattatttc ctgttttaga ttatcgaaac caaccagttg
    19801 ttaaaccaaa tgcaatgcaa atcaataact cattgaagcg atgctttgtg aaagcattgg
    19861 ctctacacgg actgggatta tatgtatttc aaggggaaga tattccaaca ccacctagaa
    19921 tcgatacaaa gaaattaaac atgctagaga cgattctaga agctttcaat gagcagatgg
    19981 gtaaagatat gaccaaaacc ttaatcgaat atgttaatga gcagacagat aaattagggc
    20041 tcttagctga taacgttgaa actattgaac agttaagcta tgagcaatgt gccttgatgg
    20101 agcgagcaat agcagctaag agaaaagaat tagataagaa gtgatatgag tgtttaaacc
    20161 attaatcgat tcatattcag cggttctgaa aaagttcaaa ggaaaagaca taagcgcaac
    20221 catcaatgag gaagtgaaca ttgatcgact aaagacgatg tatgacggct acgatggtga
    20281 tcgagttatt gaaattcgtt ttattgatcc tagacgtttc acagtacagc aacgaaactt
    20341 catctatgca ctcataggcg atattttcat cgatacaggc atgccaacgg acttctggaa
    20401 ggaattcttt tacttccgtt tcgaaggtgt cacagggcgc gaaataagcc tcaaagatga
    20461 atcgaatacg actgtgagtg atgccaatat cttagcaaat atcatcttag attttatctt
    20521 tgaacatcat attcctttca aagaaggcta tgagatttta ccagcgaatc aagaatatta
    20581 cttctacaaa tgcatcacaa aaagagtctg ctgtatctgt ggcaaaacag gagctgatat
    20641 cgatcacttt gacaaagcgc taggaagacg aaagcgcaaa gaagttgatc attcagagta
    20701 cacatttgca gcactctgta gaattcatca cacggagaaa cacaaaatag gtgtgaccaa
    20761 tttcaaaaat aagtatcaaa tcaaagggat taagttaaac caggagacaa tcaagaaatt
    20821 aagaatcggg ggctaatgat gattaattta aacgcagtag cgtttgaaca aacatggcgc
    20881 actaagtata aaaaaatgag tccaagagac aaattgttct tagaaatcat gacatttgct
    20941 ttcattggta cacaagctga acaaagcgat attagtgttg aaaaaattaa gacgaataga
    21001 ttagttaatg gaattacaga gacttgttac cagtacacga ttatcgtcgt ggatgaggag
    21061 gaataatttt ggcagaaaga agaatgttcg caaagacaat tattgattct gatgcattcc
    21121 tagatatgcc tttatcgaca caggcattat atttccatct atcaatgcgc gcagatgatg
    21181 atggatttat taataatccc aaaaaaatac aacgtatggt tggttgtggt gatgatgatt
    21241 taaaactgct tatggcaaaa agattcatct tagttttcga gagcggtgtg atcgtcatta
    21301 agcattggaa aatacacaac tatattcgta atgatcgtta caaacccacg ttatatcagg
    21361 atgaaaaagc tttactagca gacaaagata acaaagctta tacatttgca gaagagcttt
    21421 ctaaacatga tgaaaaactt ggtataccag atgacaacca agcggtatac caaatggata
    21481 cacaggttag gttaggtaag gataggttag gtaaggatag taaagagata aaagatttaa
    21541 cgccttcgaa aaaatcgaag gctaagccca tccgtcataa atacggagag tataaaaatg
    21601 ttcttttgtc agatgagcag atggagaaac tcaaaacaga attccctaat gattaccaag
    21661 agcgaatcga acgactgtca gagtattgtg aatcatctgg taagacttat aaaaactatt
    21721 tggcaactat tcgaagttgg gcaaggaaag aaaaaagtga acctaagaac gcaagcagtg
    21781 gatacaagcg cacaggaaga cgagagaagc ttcctgaatg ggcaatcgac caagaagcct
    21841 atctcaagaa aaaagcgcta gaacgagcta atagacaatc aaaagcacca ttttaagagg
    21901 tggaaaattg aaaatcgatt atctagaact aattaatgaa atagcaaagt ataaaactgg
    21961 tgaggaaata gaaatcctga gagacgtata tgatcaactc gaagaagctg gaatcgaagg
    22021 aattaataat gatcgttcga gttggagtaa actcagatac tatttcgcac tctatatcga
    22081 tacaacacaa ttaagaaatt tagcttatac aaaattacta tttgttgatt gcgttaaagg
    22141 attgcaaaaa catcttagtg aacttgagca ggtgtaatca gatggatcta aaaacattta
    22201 cagcacagat cgaactaatg catcaagaag ctttaagaca aagcgcctcg tacgaagaca
    22261 agtggctcaa cacgttccat ggtggacgtg agagcgcact tgatcaagta ctcaaattat
    22321 tgaaagggga acgtcgggat ggataagaaa gcggcaatga aacgaatcat cgaactgaca
    22381 cattctgaga attggcaaga agacaaagaa atagttacag aagtccaaaa gctcggtaaa
    22441 tcaatgtgga ctgaaaagcc caaacggaga acgccgagaa agattgcaat ttggcatggt
    22501 gatcgaattc tagtaacagg tactgctgaa cagttatctg aaattactgg tctgagcaaa
    22561 aacatcatct gggatagagc aaggagctta tggattgatt caaaaggacg acaatttagg
    22621 tatgtggagg agaaaaaatg aacgaactaa tcacaaaagt agagcagtgg gctaaagaca
    22681 agggactgga tcaagcagat ccaaaagcac agtttttgaa agtagctgag gaattcgggg
    22741 aaatcgcttc agcaatggca agaagtaatg atgagctatt taaagatagc gtaggagacg
    22801 taatcgtcac gttgattatc ctttccatgc aaaaagggac aaacgtacaa gagtgtttag
    22861 aaatggcata caacgaaatc aaagggcgca caggaaaaat ggtagatggt gtattcgtga
    22921 agtcgagtga tttggaggac agcaaatgat aggtttaaca atattttggt gtgcgattgg
    22981 tggtttacta gcatttctag gatactacct catctgtgaa agtagaaaag gaagaaaata
    23041 tacagtgaca ggtattgtcc tgttaattat cggaattcta gttgcagttg gagcagaact
    23101 gaatctttat gtaaatggta cacaagaaga tttggtgcga tttatgtttt ggatgaagaa
    23161 ttaggaggaa aaaaatgaac gaaaacaaat taatcaaatt aggtgtagca ggagcagtaa
    23221 tcgtaggtat tggagttatc ggaggattta agttcttcga aaaaatcgat aatggatatg
    23281 tgggtgtgcg ctattcaatg aacggcggta tcaaagatga agcactgacg caaggtgtga
    23341 aatttgtagg gattgacaaa gtgatccaat atccaattcg cttgcaaact atccaatcaa
    23401 aaaatatttc agtatctaca agcgacggca aaaagacaac gattgatatc aaatatgact
    23461 acaaagttga ttcaactaaa gcagcaaaaa tgtacaagga atttgggaat atcacttcgg
    23521 aagatatcga aagtggatgg ttaaaatcta agcttcaaaa ggtcgctcgt gaagtttatg
    23581 cgaaatatag tctgcttgat gtcctttcag gagattcctc taaagttgaa gctgaggtat
    23641 taacgaactt tgctaaatca gttgaatcta aagggtttga agtcgaagac gtaacacttg
    23701 gtgttccaga tgtcgataaa gaaacacaaa aatcaatcga tgcgatcatt cgagctggtc
    23761 aagaaaatga aaaagcgaag ctagatgcag aaactgcaaa aactcaagct gatagtgaag
    23821 cttacaagaa aacaaaagct gcagaagcag aggcagaatc taatcgcaaa gtcgccgaat
    23881 cagtaacaga caatttgatt cgttatgaag aagctcaagc tcgcaaaaag catggatggg
    23941 taacagtaaa tggagcagat actgtagtta cggatgaagc aggcaaataa tatgggattc
    24001 tttatggcta aaattctctt gttcttaggt ttagtaggag cagcatatct cgtgtatgcg
    24061 ctcctttccc aaactgatga caaagaagat gacaacaacg atgaaatgaa attttaggag
    24121 gagaaataat ggatctcatt acacaataca gtgatatcat cctcaagaaa atcatggcaa
    24181 agattcagaa agataaaaaa gcaaaagaac gagcggaatt agttaagttg gaaatggctg
    24241 aaacaggagt aggagtgcga agtagcaggc attggaaagc agcagcaaac attgaatttt
    24301 attacaacga aattcaaaaa gggttcgatc agatgcgtga gctggatcgg caaacaaatt
    24361 ggagcaagaa acttcatcaa gatcgtttca aatttgtaga gaagtataaa gaaatattag
    24421 aagagtattt gaggaggaca gcgaatgata aaaaagctca ttcaattcag catggattta
    24481 tatgatatcg aatcaggagc aacagtatct gtggagtctg atcatttaat cataagtttt
    24541 gctgacgaac gtcaaattat catatgggta gttgacgata tgctatatcc agaaattgta
    24601 catgattttg aagaatcaaa agcggttgag tttgaaatag tgaaaaaagt aatggaattg
    24661 attgaaaaat acgaggagga cagcaaatga taccgaagtt tagagcgtgg gataagcgag
    24721 aaaacacaat gagagatgta gctgtcttac attttactaa aaacggcaaa acaaacttta
    24781 ttgaatattg gataaatcct accgaattga aatcatatca cgtgcgaaac atcgacctca
    24841 tgcaatccac aggaatgaaa gataagaatg gtgtggagat atttgaaggg gatgtagtaa
    24901 ttacatcaaa aggagcgatt ggatatgttg cgtatcttca acaagaagcc ggctttgtag
    24961 ttgtactaaa gaaaagtgat tatagattag gccataggaa tactggcgaa agttatgatg
    25021 tagcaactgc tcatgaagtc atcggaaata tatacgagaa tagcgagtta ttggaggtag
    25081 agtgattatc ttagctactg actacatcga ttctttaaaa gatgaaaatg ggaatgtccc
    25141 agcattgcta aattgtggaa ttaaaagcaa gaatagaatc attttgttac ggatatcggc
    25201 tgatttagca aaatatcttt atctgagcaa gacagcagta tattacactg cggctacacg
    25261 ttatcagtac aagggaaaaa caatcagtca ggattattat gatcgtttaa tcagtcctga
    25321 catgcatgga aaatcaaaat cagcgatcaa gttatttggc gcaatagaga tatatgccga
    25381 tgattttcca aatttatggt tgaaggagga agcggaatga aatacgaaat accactaagt
    25441 gaagcgggca ttcaagcaat tatcaatggt cgggaggtta ataaaaaact tcctgatggt
    25501 actgaattag tcatcagaca aagttatttg aaagatatgg cagctccagt attaattgat
    25561 cgttttaacg tgactgattc tgtggtagag aaccacttga aagaatttcg atcaagtata
    25621 aacgacactt tcagattagg gagttgattg acaatgaaca ccagacaccg cagagtagca
    25681 aaactaagaa aacaggaact gaatgtacta aagacaaagt ttgaaaaaga atatggaatt
    25741 tcagcagaag aaacatataa agtggcaagt cagtttgttg ctgatgcgag tgagactatt
    25801 cgtaagtttg ggatttcgat attaaatgat gatcgtaaat gggaggcaga aagatgaaac
    25861 taaaagacgg attttacact gatgcttatg gaattggtgg tttgatgatg gatctaccaa
    25921 ctaagaatcc tataaagcaa gaggaatcag aaattaaagt cggtgacatg gttcgctgcg
    25981 aagcagaagg gttcatctat ccatttcgtg gatatgtaga gcatctctat aatcactcag
    26041 cgatcattcg cattgaaaac acgatggaat gtgacaagcg gttagcgaaa agcaaagaga
    26101 atttagcagt ggtgagattg gtggatatgg aagttataaa atcttaattt tgctttttta
    26161 caactatcct acaacaatga gcgttattcc acaactggaa ggagaagagg caattgtgaa
    26221 cattttagag aatatagata ttaagcaaac aaggaaaaat gctagacgat tactaaaaag
    26281 atacagaaat ttagaacgtt tggtcggacc agtgaaaata gacttttccg tgatgactgt
    26341 taccaaaaat ttgaaattca caattgacag tcaaaacgaa gaaatcattg aagcgataag
    26401 tactcgagat tcggttatcg aagcattaac acggctaagt agaatccatt tccaggtact
    26461 ttattatagt tattgttttc ctaataagat gtcaatgtat caaataggag aaaaattagg
    26521 atattccgat agaactatcg agagaatgaa ggcagtagct ttggttgaat ttgctgaggc
    26581 gtataaatca ggagaactca tttcacgtac aaaataaaaa aagtcggatt cctccgacta
    26641 tgaataatat ttccgacata agtattatat cataattggg ggaatcagag gatggtactt
    26701 ttcgatgtaa agaaatatga gacaccaagc gcgaaagatg ttgatatgga acgcacaaaa
    26761 cataatgtcg ctgtgtttct ttcagcatat ctatcagcta gatgtagagt agggcaacct
    26821 cgagaaccaa aagtgacagc atcttattcc ttggttccac cttctacagc tgatcatata
    26881 tttgaagcag aaagaatgct gatcgataaa gaagaagcac aggaagaatt tgagtatctg
    26941 cataaattgt ttgttcgagg ctattcagcg atacagcatc cgcataagcc tgatgtgact
    27001 gaaaggcgca agaagatatt ctatgatcgt tatatcaatg gtctgcccat ttatgtaact
    27061 gctcaaagga ataatactag cgaagaatcg gttaaagtag aatcaaacag aattatcatc
    27121 caatttgctt catcgttaga actggttgct ttcaagtagc cagtttttac actttttata
    27181 cccttttatt accaatttgg tttccatttt ataccttttt tataccaatc acttacctat
    27241 tcaacgttgt attatgatag tgtcgaaaga ttagtgatag gtcttagaca aaataaaatg
    27301 taagggagga aatctccctc atcgttttaa attaagcctc gatagacagc agcggaaata
    27361 ttaagaataa ggatgtgaac tcaactcctt ctgaattctt cgtatgctgc tgtctattaa
    27421 attatgtgtt ggagggtaag aatatgaaat tatcgattga aggtacttca ggagaaataa
    27481 aagaaatcct ctcagctatt tgtaatagcc gagagattag caatttaatc aatatagata
    27541 atttaaatga atctattgtt actccaagtt cccgagagaa attgcagaaa tctgatcagc
    27601 aaaaacaact aaaaatggga tattagtagt tctctcgcct atgatggtaa catctttcag
    27661 aaagatagat ttgactacca aactttgctc atcatctttt tctatatcat caattttttt
    27721 tgagcgaaat tctgcaaaag aatccatcat agcatcaata agaggattta cttttacttc
    27781 agcatcaaag tctataggag ttccgcaaat tgttgctcct ccagtttgaa taataatatt
    27841 attgttagaa tttttagcga agagttcaat atattcaatc atgtctgaac ggtaatcatc
    27901 aatttttgcc atttttttac caccttaaat tatttcagcg gaccactcgc tgataactaa
    27961 aattatacgc ttagtattta ttttcacaat attaatttgt cactgtggcg gaaaggtaga
    28021 cgctaagcat gcgtgctagg tcaatgcttc ggcaaccatg caatgttcga ttcattgcca
    28081 gtgacttaag gaacctacgg aaacaattca tcttatcgga tgccgatgaa ttggctgact
    28141 agtcgggatg ccactagcag ttaaaaggca taaaatacta gcgcagacgt gcgccactct
    28201 caggtgtagg ttaggagaga aacattaatt ggggttatta ggaatacgat aacctgcttg
    28261 cgacaaagct ttgtactgtc gcgttggtca tggacagaga cggtattctg tttcagtatt
    28321 cgttagcaac cgaagaatcg gcggtttaaa aatatagggg tgcgcaattt cgtacgcgtt
    28381 ttgtgcatcg tgtaggttgc tattacatat tagatcactc atcgagtgat ctttttattt
    28441 tgaaagggga gtaaacaaat gaacgaaaac caattaagag agttgtttaa aacgaatgaa
    28501 gcaaacaaaa caatggaggc gacattctac gaaactcaaa aaagcttagc gttaatcgca
    28561 aaacaatcaa agtatttcta cgatcagctt attctgcaag gatttaatga aggacaggct
    28621 atggaattta tgatgcgaac cttttctgcc agtaaccaac agaaagagtg atacataatg
    28681 agaaactact ggtatatatc gctaactaat gaatatcctc gaaccattga tgattgttca
    28741 gtgcgtgttg tgcgttctgt acaaatcaaa aagaagtact ccatcattga aatgaccaga
    28801 gaagctacac caaatgagat cgataagtac aatcttcgtt actgtggcca tggatattgg
    28861 aaagacgaat atattcaaca aaacattgag aggtacatca aatgaatgat aactatgatt
    28921 acatcaagtt gattgaaaag ataagagcag aaaaagatat ggacgaacta gctaacttat
    28981 tcatgaacat cattagtttg gtggggttaa agatggatga agtagcggca ctaaattatt
    29041 tcatcgctga gcaaacaatt agagcagagc acaatgctaa gttcttgaaa gataggttag
    29101 atctagatgt aaaaggatta ggcgttgaag ggatattcaa agtgcaagaa gccttagtga
    29161 atgtttatgt cgaaaagatg caatagcatt aacaagtaat tattggatgt tttcaggagg
    29221 gaaactatga aattaaaaga ttatatcagg gaagggtata acattgtaac tacaccaaat
    29281 ctagcttaca aaattcaaga agattatccc aatgttttag tgtttactga tagagcttta
    29341 gatgccattc ctatagggaa gttattagta gatcgttatt atagcaacaa tccagctgtt
    29401 cttagtgcta agccacttca aaacgcttat gctattgaac gctttacttg cgagtttact
    29461 ggatatgaga cggtagtacc aatgacaggc gagacaggaa gaaaagtaat tcaacagatc
    29521 aaaaagagga ttgctgaatt gacgttagat gatggaagta atacgaacct tctagaaatc
    29581 aaactaagag atactgactc agtaccagaa gtttattata aaggtcaacg aatggatgag
    29641 atgccgatag gtcttgtcga tattacttat cattggcata cggaagaata tgaatgccaa
    29701 gtaccaaaag gagctaacga catcactatt gaatattatg attcacataa taacaagtac
    29761 ttagatagaa aaatcattgg gcacaagaga gatatgtaaa tgattgatgt ttcaactaaa
    29821 caagcaagag ctaggttcta tggatcaact gagtggagga aacttagaag tcaatgctta
    29881 gagcgagatc attatgagtg ccaatggtgt aaagcagagg gtagactaac aactcaacat
    29941 gattcaattc ttgaagtgga tcatataaag gagctggagt atcatccgga tttagctcta
    30001 gatataaaca acctaagaac cttatgcaaa gattgccata acaaaaggca caaccgtatg
    30061 aaatatcgtg gccaacaaaa gaaaagaaag tgggatgatg aatggtggta agaaaaacag
    30121 caaacagaga tgatgtcaaa cgagcagaag caatcgctat ggttgataag gctattgata
    30181 agttggttct atttaagagt cagctcattg aagaaacaac aactgtagag gatatatcta
    30241 tcaacaatag actaataggt aacgctaatg aagtaacagg gacatttaat attaatgtag
    30301 acattgatta taccttgagt ccatttgcac atattgtaga aagcaacgag caagacggct
    30361 gataaatcag tataaagcga agatatatag agtgaaatac ccccggtcaa aagattttga
    30421 gaagaaataa aatttttggg aaccggtgga tggggttaat tctgcaaatg caacgtattt
    30481 attttacccc tcccccctcc gccgcccctt tagtaaatat agaaggaagg tgattggttt
    30541 gaattctaag ttggttggca cgagaatgaa acaaaaaaga attgaaaaag gattgacaca
    30601 ggctgatgta gcaacgaaaa gtggtatttc tagtaggtat tatggaagta ttgaaaatgg
    30661 gaaaaattcc cctagtatcg aaacgttaaa ctcaatttcc atcgtcattg gatgcagttt
    30721 acatttctta ctcaatgatc gcatggacga catggaaaaa cgcgtagagc tagaaaagaa
    30781 acgtctgcag aagatattcg ataaaattcc tcatgacaaa cttaatttag ttgaagggct
    30841 gatcattcag gcagcaaggt tacgtgtctt gttggatgat aactggaagg acatcattga
    30901 aaacggggag tacgagaaat ttaaacaaag cgagaaccaa attgcttatg atagaaagcg
    30961 tcctatagtt gaaaattatg ataatcgaga taaaacttat caagccatcg tcaaacaact
    31021 caccgattta ttaccgcaag gcacaagagc ggacaagaaa agtaagttac tcggtaggaa
    31081 ataaaaatgc tttttaacca gcacgttgat caatatattc gtaaatggaa atctggtgag
    31141 ttaatcctta acgaaaaaag gatacaactt ttaaaactaa tagaaaaaga aatattacct
    31201 cgcgacgaca tttattactt cgacgaggag caaataaata attatatcga gtttagtcaa
    31261 gcatggtatt ttgagttaga tgaatgggag aaatttattt ctgcattcat ttttttgttt
    31321 tataaagaag atgacgaagt tgtttttgat gaatttgtta ttaatatggg gcgtggcggg
    31381 ggtaaaaatg gctttatttc aacattggca aattattttg tcagttcgct tcacgggatt
    31441 gattactatg atgtttcaat tgtagctaat agtgagaaac aagcaaaaag aagttttcaa
    31501 gaatgctatc gagtaatcaa taaaaaagga aatgaagatt taaaagaaga gtttgaagcg
    31561 tataaaagca gtctaaccgg tttagagaca cagtctgttt ttgagtacaa aactagtaat
    31621 gcaagctctc aagatggcgg tcgagaaggt gcagtaatat acgacgaata ccacgaaatg
    31681 gaaaacacag atattgtaga tgtgttttct ggtggactgg ggaaagttga tcacggacgg
    31741 caatttttca ttggtactaa ggggtttgtt cgtgaaggtt actttgatat taaatataga
    31801 gagtgtgaag atattttaaa tggtttgtca gagttcaagg gtgtatttcc gtacatatgc
    31861 gaactggatg ccattgaaga aatggatgac cccaaaaatt ggccgaaagc aaacccggca
    31921 ctgcaaccac cgttgaataa acgtgggaaa cgtctgttta acgaagtcat gaaaaagtac
    31981 aaaaagttag ctaaagaacc ttctggacgc tcggcatttg ttactaaacg aatgaatttt
    32041 cttgaagaca atatggaaaa ctctgttgct tcaagagaag aaataatggc aacaaatcgt
    32101 ccattttttg aactagatac ggtaccgatt ggatctctcg atttcggtag tgttcgagat
    32161 tttgctactt gcggtttgct atttaaaaat cgaaagaaat cggaatacgc gtttaaatca
    32221 tttacgtttg caatgaaaaa tttttgcgac gttcattatg gatactcgtt gaaagagcaa
    32281 ttggttggca gtgaaaaacg ggcaccaata aaaacttggg aaaaaatggg gctgatgaaa
    32341 gttattgacg agccatcttt aaatcctaag tatattgttg attggtttat tcaagctaga
    32401 gaagaatatg gagtgagagt aattgtcgtg gataactata aggcagatat tttagggcct
    32461 atgcttgaaa aagaaggatt tgaagtagtt cgactaaaaa gaccatctag tttacatcca
    32521 ttattagctc ctcgtataga agatggattt gcaaatcaca aatttatttt tggagataat
    32581 ccgttaatgc gttggtttac taataatgtg tacgtaaagg aaacgcaagc aggcaaacaa
    32641 ttcttaaaaa aagaggaagt caagcgtaaa actgatgggt tccaagcatt tgtacacgca
    32701 ttgtacaaag ctacagaatt agatgaacag attgattacg atgatgcttt tgatatgttg
    32761 gatgagattg aattttaagg tatacttttc tttacaaagg ggtgctttca tgaggataaa
    32821 aggaaaaaac atatcttggg tattttacat gttggggatt ttagctttta catttgtggc
    32881 aataaaacta tcagaaatta ttattccaaa tgacagtgta gtttcaaaga atttggtttt
    32941 agaaagagct aaactaatta tttcaatttt aggaccagca ttaacactaa ttgtttttgt
    33001 tcgaacaatt caaactcaat tagaatcttc aaaaaactta attaaagata acgtcagtaa
    33061 agatttttat aatttgctaa atttattcaa aagtatacag gataaaatga attctgaatt
    33121 atttagtaca attgaaaaaa gaattaaagt acctataaat aatataaata caaatttaga
    33181 tgttagagaa aataaagaaa ctactaaaga agtacaggag gatttaaaag aatatagtgc
    33241 atcattgaat aaagttttaa gcgaaagcgt taaaaaaatt aatgaaatat ttgaggataa
    33301 ctacaaagac ataggtagtt atctaaaagt attccatagg attcttaaaa tactaaataa
    33361 caggtatgaa tcaaaagata tttcgcatga agaatacaaa atgtatgttg gcatattacg
    33421 tagtcagatt gaagattacg aattttatat aattcttata aattctttgt ttactcttcg
    33481 cggaacgggt atggggattg agttaattga aacatcattc tttggtgatg aactagatat
    33541 tgatttaaaa cagcatttcg aacatccaga gtttttaact gaaatcatta aggataattt
    33601 tgttgaaaag aaatcgtatc gtgaatcagt aaaaacaaga aaaaaaatag aaaactattt
    33661 gaaaatagaa agataaatga taacttatta tctcttttga gaataagata cacgttacaa
    33721 gatggaaata aaattattat aagtaatgga gtatagtcct agaaataggg ctttttattt
    33781 taccttgaaa ggtggtgaaa atatgtgagt ttatttgata tctttaagca atcaataaag
    33841 aacgaagatc catcggattg gattcctgac tttgtgtttg gtgatgaaga atctgctaga
    33901 gcatatttga aaatcatggc taaaagtaca gttcttgatt ttgttgcaag aactatgtca
    33961 acgttagaag ttaagtttaa aaataaagat gggacatcag attgggatta cattctaaat
    34021 gtccgaccta attctgatat gtcagcagct acattttggc aaaaattttt ttatcggctc
    34081 ttagatgaca acgaagtgtt agtgatattt acagatgata atcaattgct gattgctgat
    34141 gattttagtc gaacagagta tgccgtgtat gatgatgttt ttacaaatgt gatggtgaaa
    34201 aattttgtct ttgaacgttc atgggccatg tctgacgtca tttatatgga atataataac
    34261 gaagaattag aaaggtttac acgaggttta tttgaagatt acgccgagtt gttcggacgg
    34321 attctagaag ttgcaatgcg caataaccaa attcgtgggt ctgtctccat tgattcaaca
    34381 ggaacggcaa atgatgaaaa aggaaaagat ggtaagacta gatctcaaag attacaagaa
    34441 tatattgata agatttggaa ctcttttaaa actaactcag ttgcaattgt tcccaaagtg
    34501 aaaggctttg agtatgagga atacaccaat aaacaaggcg tatcgaatca atcactagat
    34561 gaactgaata agatgaagtc gtctttaatt gccgatgttg ccaacgccat aggagtacct
    34621 acggcgctta tttatggcga aaaagctgaa ctagattcaa atattaaagc ttttcgtaaa
    34681 ttgtgtattg ctccactagt taaaaaactt caggacgaat tggtggcaaa aataattagt
    34741 cgacaagagt acaaaaacgg ggaacgtata gaagttaaaa aagttctcca aaaagatcta
    34801 ttagagtatg ctactcaaat tgacaaaata acatctggtg gtgcgtttta tattgacgaa
    34861 gttcgtgatg aagttgatta tgatgagttg ccaaataatg aaggaaaaat tcgtattcgt
    34921 acgaaaaact atgaagaaac tgtgaaggga ggtgagaacg acaatgccga aagctaaaaa
    34981 agtaccattt cagtttacta acgaaattca gaatggtaag cacattctca ccttgagtgg
    35041 aaatgtacag aaaaaatatt ggcgtgatga tgatgtcata aacgctaaag atattcgtga
    35101 ctctctagat actgtaaccg atgatattgt aatcaagttg aacagcccag gcggtgatgt
    35161 gtttgaaggg attgagattt acaattattt aaaagatcac ccatcaaata ttactgtaga
    35221 agttacaggg cttgccgcaa gcgcagcaac gtttattgtc gctggtgcca atgatgtgat
    35281 tatgaatgtt gggacttctt tgatgattca tgaagcttct acatttgctt gggggaataa
    35341 acaggacatc caaaaaacgt taaacgcatt ggaaacgatc gatgattcta tcttagctat
    35401 ttattcagat aagactggcc aatctgttga taagttgcgt gaatggatga atgaagaaaa
    35461 atggtttaca gcagatgaag ctgtcaaata tggatttgcc aattctgtga agcgtgaaga
    35521 accacaaaac gaacctcaaa atattgcagc gatgattcaa gatgctgttg ccgttgcaat
    35581 agcgaattta aaggaacctg ttactaataa aatcgaacaa gaatcaaaac aaaaatcatt
    35641 aatcgcacga ttgcgaaaag gagaataaag atatgttaaa aattacagat aaaactgcag
    35701 atgcaaaaaa ggcatttaat gctatttctt cgaaagaaga tgcaacaccc gaacaaatta
    35761 atgctgctct agaagaatat gtaactgcca ttgcagaaga tgccggcaaa caggtgcgtg
    35821 ctgaatatga agaattgaaa aatgtgacgg acaatcgtgt attagaggct cgtggaattc
    35881 ctacactaac agtagaagaa acaaagtttt ataatgaagc cgtaaaatct ggaggtttcg
    35941 attctgacgt agtttggcca gaaacgattt tggaacgtgt ttttgaaaat cttcaaaacg
    36001 atcatcctat tttaggcctc attaacttta caccaactgt aggtcgtgtc aaagtaatta
    36061 gagcacgtcg taaaggtgtt gctgtttttg gaccattgca taaagacctt gaaggccaac
    36121 tagatgctga atttggtgca actgaatttg ttcaacttgc gttgaccgca tttttcttaa
    36181 tttctaatga taccttagat ttaggaccac gatggattga ccgttttatc aatctttctt
    36241 taagtgaagc agtacgtgat gtttgggcta aaaaaattat tacaggttct ggtaaagatg
    36301 agccaattgg attgcttaaa gatctagatg gtgcggtcac aagtggtgta tatccagata
    36361 aagctagcgc agggacatta acttttgcga aagagaagat tgttcttgaa cttgcagggg
    36421 tgatgaaaaa attatctaaa tacacataca aagtagatgg tgacgatgaa ggtgaagtgg
    36481 aataccgttc tgttgctgga cgagtgtatc taattgttaa tcctgttgat tactgggata
    36541 tcgtagctag agttacattt gcaaatttaa acaatgtgta tgggactacg atgccattta
    36601 tcgctgttga tcatatcatc gaatctgtag acgtaccaga aagtaaatgc attgcatacg
    36661 ttgataaaga gtatgaagct actcaatcaa gagctgaaaa agtctatgta tataaagaaa
    36721 cttttgcaat gaaacgcgca actttgtatg ctgtcgacat gcttggtaat ggctatccaa
    36781 caaataatga tgcagcacaa gtatatgact tggactttac agcgggggag taacgtcccc
    36841 tgcaattggt gagataacac cgacgactga tggggcagtc attaatcttt cgtaaatggg
    36901 gttagagtat gaacactgaa gaatttataa aagaatataa ggcccgattt cgtattttcc
    36961 atacttccga agatgaggat atcgggaaac agttagagag cgggtttgcc gatataaaat
    37021 ctctaatcgg cagttttgat ccttccactt atgagaaagg aaaagaatta gtttatgaac
    37081 gtactcggta tctacggaac gaatcactag agtactttta cgacaatttt caaacaatga
    37141 ttatggatgc atcaattgat ctggcaggtg ctggatatgc caattaaatc aaattataag
    37201 aagcctaaaa ttgtagctgg tgatctaaat acgccagtta ctttttttga gtttcaacct
    37261 aataagggtc cagaacctgg tgatgaagaa aaaaaggaac tgtatttttg tacagcacta
    37321 gtttacaacc catcaatgaa agatcgtgac attcttggca caaaagaagg cgttacgata
    37381 aaaatacggg atccccatca atcttatatt cctactaaca aacataaagt aaggatatta
    37441 gattatcgat atggagataa agtttgggaa ataatcgatg tctcaccgga tttggaagaa
    37501 aattcaattg taaagatagt attagaatta attacttaaa tttggtgata aacgatgagt
    37561 aacgtaaagt ttgaaggcgt tcaagaaaca atccaagctt tagaaaaaaa gtttggagaa
    37621 aagaaaacta agacattaac aaaaaaagca atcaatgttg gcgctgaaaa agtagaaaaa
    37681 cagttgcaaa cggacatgac cgtttttaaa gacaaaggtt atacgattga tgaggttgta
    37741 cgtaagaacg ctacgtatag aaattacaag gcagaagctg aaatcggttg gaatggtcct
    37801 catcagcgtt atagaatcat tcacttaaat gaatggggat atacacgaaa aggtaagcaa
    37861 attaggccaa gaggttttgg cgtaatcact aaatcgctta aaaattccga gccactatat
    37921 tttgatgctg ttggggagga ggttaaaaag agattatgaa agatatgctc aatatcattt
    37981 atgaggctct ttgtttgaat gagtatattc gttcaatgac atataacgag aataccgagc
    38041 aatatcgtat taaattttat gagcaacctg aaaccgccga taaaacaggg ccaatgatca
    38101 cacttcgtcc tgtagataca cctaacgaag catatcacgg aagtaacaaa gagctttctg
    38161 tagagcatat ggtacagatt gatgttgaat cgaaatatag agcaacatgc aagcagattc
    38221 aatatgagat aaaaaaagag atgaaaaaac taggctttgg ccaaatttct ggtcaagggt
    38281 tagatgaata cttttctgaa acaaaacgct ttgtagacgc gcgtcgttac gaaggaaata
    38341 caaaaattta cgataccgaa tattagaaat taagacacga aaataacgtg tcttttttta
    38401 ttacccaaaa ttaggaggaa aattttatga ctttagtagg attcaaaaaa atgacaatcg
    38461 ggatctttga cagcacaggg aagattccag cagcaaattt atatgtaatt gaaggtgaac
    38521 aagacaaagg ggcgactgta tctgctgaaa tcagtgggct atcaaaagaa ccatcaaaag
    38581 tttacggatc gaacatcgct tactatgtct ctcaaaaagg aacaggcgat gtttcagcta
    38641 cttttggatt gttagattta ccaacagaag taaatgacaa aattcttggt tacaaaaccg
    38701 atacaaacaa aatcagcttc ttgggagaag atactgagcc accatattgt gcaattttga
    38761 tggaatcgga ggatttgaac ggcgatacag caatgcttgc gatgttcaaa ggaaaattca
    38821 gtcgtgaatc tattaatctt aacactacga caaatgaagc tttcgaacca gaagcagaag
    38881 aatatgtatt ttcagcgatt gccaatgatg ttgaaggtga tgctaaaggc caaacagtcg
    38941 caaaatatgt tggagacgaa gaagcttcta ttactgcttt gaaagagatg gtatttcctg
    39001 cagcggggga gtaactagct ccgttgttgg agcaatcact cccactatta atggggtaac
    39061 agttgaatta agttaggagg ataactatgc cagatacatt taaaatctat aaaaaaaatg
    39121 gtactgaatt tacaaaagtc gcagagggtg aaagtccact ttctattact ggaattgcag
    39181 caaatactca agttgctaaa ggagactacc aagctacgcg tgtggttgga ggtcaagaat
    39241 cagtaaaagt agatattcct gcatttacca ctcttccaat ttcagttact ggtgtgacgt
    39301 tggataaaac gacagctgaa gtcgaacaag gcggaacctt aaaattaact cctactgtaa
    39361 caccagcaaa tgcaacagac aaaacaggaa gctggagcag ttcgaataca gctgtagcta
    39421 ctgttactgg aggcaacgtt acagtaaaaa cagacgctga agttggcgga actacagaag
    39481 tttcatttac tactacggat ggcggtaaag tagcaaaatg tactattaca gttattgaaa
    39541 aagcagcggg ctagtcttcg gactagcttt tttatttgga aaataatgga ggaatctaaa
    39601 tggcaaaagt aagaattgaa ttgaaagaag aatcaggaaa gaaagtctat gaaaacatag
    39661 acacaacagg taaagattat cgaaaagctt tagaaacaat caaaaagcta aatgaagatg
    39721 gagtaatgat ttggaatcgt ttagacattt atttggattt tgctgtaggt atcttcaggg
    39781 atagcaaatt gacagctgaa caaattcttg atggcttacc atctgagaag gtaatgagca
    39841 cattggacga catcctagga gaagtaatgg ggattgaaag taatccagac ccagacgcaa
    39901 aaaagtaaca cccgaagaag cagaagaaat gtacttaaac ctatgcagag agttagtgaa
    39961 agcgggatgg tcactatctg acatagaaga taattccttt gaaatgatga tgaaaattgc
    40021 gtgcacttcg cctaagaaag agaaacaaaa agaagttgat cttaaagact tcttgaaatc
    40081 catgtagaga ggaggtaaac atatggcaaa tggaaaacct ttaggcaata tgattataaa
    40141 actagactta gacagttcag ctttttcaaa aggtctagcc ggagctaaaa acgctgttaa
    40201 ccatcaaatg aaagcaatga aatcacagat gcaagtaatg aactcttcag ggaattctct
    40261 cggtgcttta caagcaaaat ataatggttt aggcggagtt ctacaagcaa atgaaaagca
    40321 agtagaattg ctcactaagg cttataagga tagttttgac tctaatggaa acgctactgc
    40381 ttcgactgct aaatacgcta atcaattgaa tcaagcaaca gctagatcag caagttacga
    40441 atctcagatg aaaacaaccg ttggacagat tgctcggatg aaagtggaaa cggaagggat
    40501 tacggggaaa ctaaaagcta attctgatgt attgattaat tctgggaaaa aaattgaagc
    40561 ctttggtaaa ggagtttctg ggataggatc tgccctaact gttggagtaa cagctccaat
    40621 agtggcaggt gcaactgctg ttactagtgc agctatttct tgggaaagtg cttttgcagg
    40681 agtaaaaaag acaaatgatg aagttgtaga ttcgaatggg aacgtagttt actcctacag
    40741 tgatttagaa aaaggccttc gtgatttagc gactaaattg ccagcaagcc accaagaaat
    40801 agcgaacgtt gctgaagcag caggtcaatt agggattaag acagaaaatg tagttagttt
    40861 caccaagaca atgattgata tgggcgaatc tactaatatg tcagcagaaa cagctgcaac
    40921 ttctttagca cgatttgcta atataaccca aatgtctcaa aaagactttg ataaattagg
    40981 atcagtcatt gttgatctag gtaacaattt tgctacaacc gaatcggaaa tcactgaaat
    41041 gggactgcgg ttagcgggtg ctggtaaaca gattggaatg agccaaggcg aaattctagg
    41101 atttgctact gctctatcct ctgttggtgt cgaagctgaa gcaggtgggt ctgccttttc
    41161 gaaggtcatg atccagatgc aactagctgt agaaaaagga tttggcgctt ttgatcagct
    41221 gaaacagatg gcagaagaac aaggtgttcc gtgggttaat ttagtaaatg ctgtgagaga
    41281 cggtggaaaa tcgttaaaag cagtatcaga gcaaatggga ttcacttcat ctgatttaaa
    41341 gaaaatgtat aaagaagcgg acaattcgaa aagttcgctt gaaaattttg cgaatgtggc
    41401 aggtgttaca agtgaacaat tccagaagtt gttcaagagt gatccttcag aagcaatcat
    41461 caagttcatt caaggactga aagattcaga aaaacatggg acttcagcaa tcaaagttct
    41521 ggatgacatg gatataaaag aagttcgact acgcgacagt ttattgagag ctgcaaatgc
    41581 tagtgacata ttcaaaggag caattgaaaa aggaaacggc gcgtggaaac aaaatacagc
    41641 tttaacaaat gaagctaata aaagatacga aacaactgaa tcaaagctaa agatgttgaa
    41701 aaacgaagtg attgatacag caatcgatct tggaggtcca tttgtagacg cgttgcgtga
    41761 tggtctaaat gtatcaaaac cgttgataaa aaacttaggg aatatggcga aagctttctc
    41821 agccatgagt gatgatcaac aaagaaacat tatcaaatgg gttggattag cagcagcagc
    41881 tggtccagcg ctgaagcttt taggaactgg tacttcagta ataggtaaag ttacttcaac
    41941 tactggaaga ttgacgaaaa gccttgttga tttagcagcg aaagcagcag aaaagaaggc
    42001 tctggatgcc tttgcatcgt cggtaacaac agctggtgct gcagctgcaa agacagcagg
    42061 agctggaggt attggcgggt tagtccctat gatgggaaaa acagctagtg ctgcaagtac
    42121 tgctgcgggc gctagcggaa taggcgcaat gacaacatca ctaggtttgt taggtcctgc
    42181 tctacttggt attgttggcg ttggtggcgc actagcagtt ggctatggag catggaaatt
    42241 atttggtgaa gaagcttgga attcctcgca aagagtaaag caatggggaa cagatgtcgg
    42301 tgaggaaata gataatactc ttgacggagt acagaagaat attgaaggtg caaatggtca
    42361 attcggtctt ctcaaagagg gttttactgt tgatgatgcg aataatatgg cggctaattt
    42421 cgcaaccgct ggaacatctt tggaaacatc tttaacaggt agaataaagg cattagacga
    42481 tgcactaaaa gggctacctc aatcagttca ggatgccatg aaagaagtag ctgaatcaga
    42541 agaagaaacc ttagggcaat ctctttctaa aataaaagac aacaatgaag aaataaaaaa
    42601 aatcagagaa agagccgcaa atcagaacag agacttgact gtttcagaac tacaacagat
    42661 acaggatctg atgaaaggaa cttctcaagc gtatgtggat acgctcgatg tttctgctaa
    42721 agacagaaaa aagatactat cagccatgaa tggtgatgtt gcacaggcta cagaagaaga
    42781 agcgaagacg tggttacaat ctttagcgaa acaaaaagct gcaactaccg aaaattatag
    42841 acaaatgctt gaagaaaaaa aggcggcttt aaaggaaaag ggagtaagca aagaattcat
    42901 tgatgcatta gaagatgaaa tgaatgatta catcaaaact acaaatcaag gattcgatag
    42961 ccaaatagct gctataacaa ataaatatcc acaattgatt aacgaagtga gtttatcaaa
    43021 tggtcaatta tttagcaaaa cggcagctgc tatggacaat actggtcagt atacaaaagt
    43081 ttttctcgaa agtaatgaaa agattttagc ccaagcgaag aaaacatcgg atgaaatagc
    43141 agataatgcc gaaaaaaatg cagaacaact tggtatggta gctgatgagg ctacgcatgc
    43201 tggatcaact tggaatggat tagttttaga cgaaaaaaca ggaaaagtaa aaactaacgt
    43261 acaagaagta gtgaatgaag caacgaagga tttcactaaa tggaatgaac ttaaacctgt
    43321 tgttcatgat gcgaaactaa caacgaacgc aaaagatgtc atttccatag cggcagtaca
    43381 aaatggttat tgggatgata tggaatggaa agaaaaagaa gcattattag aagatgagtg
    43441 ttctaaaaat gtatacaagg ctttagaaaa tgctggtaaa tggaatgagt tagatattcc
    43501 ttctaaagaa gcaatcctaa cttcaaatac tcctgaagtt atgggtgaaa ctctcatgaa
    43561 tttgggacta tgggatactt acaaacttca agtgaaagat ttagatttga atgcgtataa
    43621 agtatacgat gctatcgatg gatcagaaga aaaattaaat agttgggctc aattagataa
    43681 ccccacaaaa gaattgttat tagataactc agatttttct acaaaacttt ttaattccga
    43741 agaaatgttt aaacgttgga atcagttatc atctaatgca aagtttcttt cagctaataa
    43801 tactaaattt acagaggttc ttttatcatc tgacagaatg tggaatcaat gggtaaacct
    43861 tcctgataat gagaaaagat tacttgcaga taacgaagat ttagctacca ctgttttatc
    43921 ttcagaagaa atatacggaa gatggactca attaccagat aatcaaaaat atatgttagc
    43981 tgacaatact gacttagcaa acaaaatatt tgcttcagaa gaatcatgga atgcatggaa
    44041 agcaattcca gacatagtta aaaacttgct tggtaataat attgatttac tggctaaagt
    44101 gaaagatggg actgtaagtg tagaagaata taacaaagtt atgccacttc ttaaaactct
    44161 atatggagat aacgttaatt taaaagaggc aatcagtggg gctaaaagct ctatagagaa
    44221 ttacaacaaa aatatttttc ctaatgataa aactgcagta ggacacgatg aggcttcaca
    44281 agctgctaaa gatgcatttg aagcgttcaa catcttccaa acaaaaatac cagataaaat
    44341 tactaaaact gtatcagctg actttatagg tcctatgcct aatgctaaag gaacgaactt
    44401 ccatcctggc ggagcagcta tggtaaacga tcaaaaagga cctacttatg aagagcttat
    44461 aaccttgcca agcggagaag cttttatacc taaaggacgt aatgtcgttt tagacttacc
    44521 aagaggttcg aaagtactga acgccactaa aactaaacgt ctagtaccta aatatgctga
    44581 tggtatagga aacataacga cggtttcatc tacgctaaac ttagatgctt taattttagc
    44641 tattaacgag ctaacgacgg tattgagaac tcaactgatg gcagaaacga ctaatgctaa
    44701 agatactaaa ctatcagatg aaacaaaagt tgccgatccg attattccgg gcagtctttc
    44761 agaaaaatca gatcagtatc taggaattgg agctcaatgg ttaaccaatc taatgaatgg
    44821 ttggaactca gcggttcctc aatatatgaa tagtgaaatg gtttttatta caaactatct
    44881 caatgcgcta aaacttcaaa acaatcctaa ttatacgcaa ggagtagcat ggaataagaa
    44941 cttactgaat ggatggaata gtttaactgg gacatttatt tctacgatca attcattttg
    45001 taatcaagca atggtcacgc ttagaaacta caacactcct atgtacaaca atggccgaac
    45061 gtggcagcaa aataatctta atggttggaa ttcattgtat ggatcattca tagcccgtgt
    45121 aaatcagctt ggtaacgatt cgattaacaa ccttcgttct aaaagtggtg gtttttacaa
    45181 tgcagggaca ttcttgttgc aatctttaat aaacggaatg aattcgttag gtaattctct
    45241 ttctacaaca atgaacaatg tcgctaatac aatggttggt ggtatgggca aaggggttaa
    45301 tggcgtcata tcgggagtta actatgtgct taaggaagtc gagtcaagta agaatatcgg
    45361 aaactggcca attccacaat acgctaaggg aactgatgga catcctggtg gacttgctat
    45421 gattaatgat caaaaaggcc tagttcacga agaatatgta cagatgccag atggacgtgg
    45481 ttttattgcc aaaggtagag accttcttgt taatttgcct aaaggtgctc aggtcttaaa
    45541 tgcttcttta acaaagaaat taaaggaacg tttaaatatt ccacactacg aaaaaggtat
    45601 tggcaattta gatattgttg atttgttaga tgatgaaaaa agaatgttag aattcttgac
    45661 tagcaaagtt gacttttcag gcattaatga accatggctt gatatgacta aatcaggaac
    45721 gtcattaatg tctaaagctg caaatacaat gcttcaatca aaattaagtg aattcttcac
    45781 tcatggcaat tttgatggtg cagtaaatgc caatggtgtt tatcaatatt tagttgatgt
    45841 tgcacagaaa gtaatgggta agttccccgg acttacagta acttctggat atcgagcagg
    45901 agatgcttac tatcacggaa aacggcaagc tatagacttg gcttatccag gtatatctgg
    45961 agatccgaga tatacagcag cagctaatta cgcttttgaa aaattccctt caaaaattgc
    46021 gtatgtcatt acgaatggac gtgtacgtga ccgcatggga ttatctggaa cagggtcaag
    46081 cggacaatgg acgaattggc cagatggcga tcacttcgat catattcatt taaacggttc
    46141 gatggggtct ggcgatatat tcaatggagg agttggagga agtggtgttg cacgctggcg
    46201 ttcttatgtg tctaaagcat tgaaaatgaa tggattacca gctacagcag cttatataaa
    46261 tgcctggatg tcccaaatcc aaacggaatc tggtggtaat gagaaagcaa tcggcggcaa
    46321 tgatgggctc gctgaaggca atgcaacagg attacttcaa acgaaacccg gaacttttgc
    46381 agctaacgct tttcctggtc acggaaatat tatgaacgga tttgataaca tgttagcagc
    46441 aatcaattat gctaagaaac gttacggagt tgcaggtatg ttgcaagtta tcgggaaagg
    46501 acatggatat gccaatggtg gattgattac caaagacgga ctatatcgag cgggagaagg
    46561 aaataaacca gaaatggtta ttccattgac aagaaaaaca agagctattg aattgatggg
    46621 tcaagcatta gcttttcttt ctggcgatga caagaaacgc tccaacacta caaatacagc
    46681 tgataattca gcagagcttg taactttgat taaacagcaa caaaaacagc ataatgagtt
    46741 aatgatgatt cttagagcga ttcttggaaa agatttaagt ctcaagtctt ctgacattgg
    46801 gcaagctgct aatcattata tgggctctga tttgaataaa cttcgatata cgaatggagg
    46861 tgtttgataa ttgttttaca aattacagtt caatcaaaat gggaagttgt ttgatccgca
    46921 aagaaaagaa aaaattgtat gtaaagaaat caaacgtcaa gcaccagtgt atgaagtgaa
    46981 ttacgaagat tttgaaggga cgaacggtag cagagaagct aatgctagtt ttcgtccttt
    47041 tgaattagtg ctgacttttg atatctttta caaaaataag catgataaag aactgctatt
    47101 aacagagttc tatgagctaa tttttgtcgg ttatcaatat tacatttcct atgatttaag
    47161 cccaggaaaa agatttaaag taaatccaac aaatttcgaa attactgagg aagagaacga
    47221 ttattctacg atagaaataa cctttagtat tccatcaggg agtgctgaat ccagcgcaac
    47281 cactttaacg gatttcaatc tagaggaaga atggcaattc tcgcaaggtc tagtggcgga
    47341 agattacaag tatacgcatc agactagtca cttcattatt tacaatgctg gaagctttga
    47401 aattgatcca cgtgaacatt atctacggat cgcattagaa ggagaatcag aaggaaatgt
    47461 gacgattttc aataaaacaa ctggcgatcg atttatttac tatccatcac tttctacgaa
    47521 tctcggacag acattagtct tggatggcgt gattccaaaa ttgaacggtg taagttgtgg
    47581 aatcaatacg aatcacggtc tgatcaattt ggttgaggga gtcaatgaaa tcgagatcca
    47641 aaatattact cgcgtgaaat cttcatggga tttccgtttc ttatataagt aggtgattga
    47701 gtgactgagt taattattcg aaattatgaa caaaccaaag aagaaatcct tgtcggttat
    47761 gacaagggtt ctttttatga aaactggcaa caaaatgaaa cgtgggagat tggctttacc
    47821 gttaccagca attcgttgaa tcaagaagta tttgatttag tcgaatacga gtcttctgtt
    47881 ttctacaacg gacaggaatt tgtgatcaaa gaaatgactc gcaaagcact tggacaattg
    47941 ctgacgaaac aagtagttgc gacacatatc tattacaccg ttcaagatgg ttatcagtac
    48001 aacacagtga caggtgcgaa atctattagc cagttactca cgcatgtatt tagtgcaggg
    48061 agtcgcggct ttacatggga agtcattgat ccaaacaaaa aattccttac cgttgaacaa
    48121 gaaaatttcg gtaacgcgaa ttacttgaag ctgatcaatg agattctatc tgactataat
    48181 gcagtcgtga ttccgaataa taaacatcta actttctatc ctgccagtga gtacggccag
    48241 cagacggaag aacagattcg ctataaatac aatacagatg aagtgtcgtt tgatattgat
    48301 acgtattcct tgaagacgca gatcaaaggc tatggaaaat tgaaggatgg tgcaaatact
    48361 gagaatccta aagatagtga ctatatattt actcccatca cttatacaag ccctgaatca
    48421 cagaagtggg gaatcaggat acaagatcct gttaaagacg aacggtatac cgtatcaggg
    48481 aacatgctcg agcggttaaa gacagacttg caagactatc caaatatttc gggatccgta
    48541 accttgaaat ggaaaatcag tcccaacaaa ggcgatcacg tcccattcat ttatgaacct
    48601 ttgaatatta atacgtacat tcaagtggta ggaatcaaga cgtatccagc gataccaaat
    48661 aagccaccag aaatcacatt gagcaacaca aagaaaacaa tgacgtcgat actcgctgaa
    48721 atggcgaaga aaggagtgat ttgatggggt tattaaaatt aatcagtaac cgtatctcta
    48781 cggaatggaa agagaaattt aataaaaaca ttgactacct taatgatctt gaaaagaaac
    48841 tgtctgatca agacaaatca atgaacagtc gtattgataa tctcgtgctt cattcaggtg
    48901 gcgaatcgcc gaatgaagtg gttgatgctc gtgtaaataa taagggagaa acctttccta
    48961 ctttacacgg cagattggta gaacacgaaa ccctgacaga tgaacaaatt agcgaactga
    49021 atacaaacat ggatagtcaa aaagagcaag ttcaacaatt gaacaagtct gttcaacaaa
    49081 ttattggtgg atacaatgag ccaattaaca tctatgtttc taaagatggt agtgatattt
    49141 tgggtgatgg atcagaagaa aagcccttct taaccattca aacagccgta aataatgttc
    49201 ctctaattac aacgtctcaa attactattt gggtaggtag tggggcttac ttagaagata
    49261 ttatgattag aaatttaaat tttacatcat ttttaattcg acctatcgat aattttgaca
    49321 ctattgatcc attaaaatca gatttacctg ttaaaatacg atccatttgt ttcactgctt
    49381 gcaaaggtta ttgtcaagtt gctggaatgc aaattgtgga tacagcaaac ggagcagact
    49441 atggaatcag aaatgagcaa agtggctata tggcaatcaa tagatgtaaa ttcgcagaga
    49501 acacaaaaac acttgcaaga tataatgcag tttatgtcgg cggaacatca aagattaata
    49561 tgtacggaga cacgacgttg attaaccaga aagtggcaat ttacgctgta ttgatgggtg
    49621 aaatttttgt cagtgcgttt ggttcaggaa acgacgtagg aattttgtgc gagaatggca
    49681 ctgtacgagg aactgtatca acttcttttg ccacaacccc aacaaaaact actgggtacg
    49741 gtctcatcat cacgaaaggc acggtgttgc aataatggta tacaaaacaa atgaatcgat
    49801 catcatgatt caagcagaag ccactagtcc aaacaggacg aatgttgttt tttggtcgca
    49861 tgatcgagga acagctaagc ttcgaatgaa attagttcgg aaaaacggca ttcctcaaag
    49921 cttacccgaa ggcacaactg ttccgattcg cttgatgctc aaatctgcaa cggcagaagg
    49981 tggttatgga aaacatgact atctcgccac cattgaagat cgtgtaaatg gtattgtgtc
    50041 cattgtgctg gaagataata ttttaggcta tgttggaatt gtcgaaggta gtgtttatat
    50101 tgatttccca aacgaccgct cgttagatac agctggccgt tttacttttg acatcaaacg
    50161 cagtccaatc gatgatagta caccagaatt ggaagattat tatttcaatg gtttcagtca
    50221 gactattgat aaaatcgaaa aaattctagc tgatggaaag caagagattg aacagaaaat
    50281 tacggaatct gaaacgcaga ttgatgggaa actgaaagaa acaagcaaca aaatcacgaa
    50341 agccaatcaa gatgtcgcaa ctatcaatac gaatattgat aaagcaaatg atcgtattga
    50401 tcaaacgaac cagcaaataa gtgatctcgg aaagctgaaa aagatgtact ccaacagcat
    50461 cgatttcggg aactatgatt atagtggaaa tccgaatttg atggctaata taaacgctga
    50521 tagcttctcg caaggtagtg gtgccttatc tgttgtagat gatggtgacg aggtagtgat
    50581 tacgcttgat ccaaaccata aattagaaat attcaaagcg aaaagtcaac cagctctggt
    50641 agtggggaaa acatatacca tgagtgtaga aattatgtta gaagatgatt tcactggaga
    50701 ccctagtaat atatctctaa gatatattaa aatgcccagc tggttaacag tactatatac
    50761 gccttataca ttaactaata ctaagggtgt atggcaaaaa ctaactgtta ccgctaaaat
    50821 gactactgcg attgataacg ctgaaagctg gtttataatg ctacaaaata aagacgctaa
    50881 taacagccta tccggcaaac tacgtttgag acacgctaaa ctcgaagaag gctcaacagc
    50941 tacaccattc caacctaact tattagcaga accttacaac atgtgtcgcg aatatcctaa
    51001 cgaaaatatt gccgatccta aagttaagtt cccaatcgaa tctggcgacc accaaatata
    51061 tcaaggctac acagaagaag agcttatgat aggtcaaacg tatactatca cgcttaaagg
    51121 aacaaaaccc gcaagtcaaa cctttgtagc gtataatcat tggactgctc gtttaggaga
    51181 actaaagccg gttgatgggt tgacagacgt atggtctcta acattcacac caacgaatgt
    51241 tgtggcgatg cctaaacttt tccgtgttta tcagtatcca cgatcaacag taggcgcatg
    51301 ccaaattgac tggctcaaga ttgaaaaagg caacacccga acgcccaata ttagtcagtt
    51361 taaatacttc ggtgaaggat tgaaagacag caacaatccg aatgattaca gttgggatgt
    51421 cacacctgaa tatactgaaa aaggcttgaa taatgctgtt aatgtgtatg atcctcagag
    51481 agttgaaggt ttgaaaaact ttgccgatgg tattcaaata gcaggagata aagtgatcag
    51541 tgaaaatgat tgcactgttt atacattaac taaagacaac agtcaatcgt ttatcgatgg
    51601 gtatgcaaca tttattaaac acggaaaaga agttgttgta aatggtacag taaagttcaa
    51661 aaaagcttat gcttttggtg taccacttga tgatgaagtc ccagatgaat ttattgcaag
    51721 aattgttcat ggcatgctta caggtcagtc aggaacaaat agtgtatcaa aagcgatgta
    51781 cgtgcaaaaa gacttaggaa aaattatgac gaatagcgaa tttgccgcaa atgaatggtt
    51841 tacattccac ggtaattatt gggtaggagt gaaataaatg aaaaacattt ggaaatacgg
    51901 acgtactggt ggagagtacg caggaaaagt attggacgac atgcttgtat ccgttcctta
    51961 cacggatcag ccaccgctcg aaggattacg tgctgatggc gaaccgctaa cgattgctga
    52021 tcagatgttt gatcctaaac tgaaccaatg gattgtttta gcgaacacac tggatcacaa
    52081 cgatttaaac aatctcaaag cgatgtacga ggcactggaa cacgagaacg gcgatttaaa
    52141 acagctcaac gccaaactca tgctaagcga tgtagcaatt aaacaggaaa atactgcatt
    52201 gaaagaaaaa gcggatagtt tagcacaaat caattcaaaa atgatgcttg cttcgttaca
    52261 aaatagcaaa gacatttcag aaattaaaga gcaactaaat ccaactttaa agggaggtga
    52321 gtagtatgtt tagttttagc gatgtgaaaa tgatgtatga ttggggctgt tttactgacg
    52381 atcaagttcg actattcgtt ccactatgca ttacagacga agaagcagat aaaatcatta
    52441 gcaaagaaga gagcgcatct taagtgatgc gtttttttgt tggaaagttg gtggaacatg
    52501 aaagaagaag cgctccaaga cgttgtggag agattagtaa gaattgaaac aaaattagac
    52561 aactacgaat cacttagaga aaaggctgat agtgcaaaag atttagcaga taaagcctat
    52621 tcagtagcac taaacaatgc agaagacatc aaggaaatga agaacaataa taaatgggct
    52681 tggggctata tgattggctt aggcattacg atcattggct atttcttgac taaattgtaa
    52741 aggaggtgag aagaaatgat tttaccagat aagtattatc aagtcattaa atggacagtt
    52801 ttaacagtat tgccagctgc atctgcttta gtagccatgt tagggaaagc gtatggatgg
    52861 aatggaacag atatgatagt gttgactatc aatgcagtag caacattttt aggcgttatc
    52921 actggtgtgt cggcttataa tttgaaaaaa taggaggaaa caaatgaaaa agaaaattac
    52981 tattactgcg atgagcctat taacggctct ttttttattg ccaattaatg ggtttgccta
    53041 tactatcaac aatgaattta atttgggcgc aaatgaaggt agctcacaaa tagcaaataa
    53101 tcagtacatt ttactgcatg aaacggctaa tgaaacagca acaggacgca atgaagcgca
    53161 gtatatgcaa cgttcatgga ctagcgctta tactgcttat attgtgggag acggcggaat
    53221 tgtttatcaa gtcggtcaac ctggttatgt acagtacggt gctggttcgt atgctaatgc
    53281 caacagtcct gtgcagattg agttacaaca cacacatgat aaagcaacgt ttgagaaaaa
    53341 ctacaaggca tacgttgaat tggctagaga ttcagcaatg aaatatggta ttccattaac
    53401 attagacacg ccttataacc aaccaggaat caaatcacat ttatgggtaa cacaaaatat
    53461 ctggggagat catactgatc catacggtta tctttctgaa atgggcgtaa gtaaagaaaa
    53521 attagcatat gatttagctc atggatttac cgatgaaaat ccaacaactt ctgaaaacaa
    53581 gcctgtcatt gatccaacac gagctggtgc agctaatcct acactgacag atggaacgaa
    53641 ttacgcccac attgatcagt ttggagaaat cgaaaatgca aatttgcatg tagctggatg
    53701 gcacattgct aattataaat acgagtatat tttcattatg gactacaata ctggaaaaga
    53761 actagctaga gtaagagctg atgggattta tagaccagac gtaaatcaag cttataatac
    53821 tttaggaaat gttggctatc atgtatcttt caatatgcgt gatttcccta ataagaaagt
    53881 atacgtcatg atgcgggcaa cgaatgatcc agagggaaac actaaaggcg gtgcgcaaga
    53941 tttccatgac aaacgttggt atttaaatat tcctaaacga taaaaatagc tcctcgttga
    54001 ggagca
//
LOCUS       DACGMI010000012        53769 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.012, whole genome shotgun sequence.
ACCESSION   DACGMI010000012 DACGMI010000000
VERSION     DACGMI010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.012"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            169..948
                     /locus_tag="IXT46_000847"
     CDS             169..948
                     /locus_tag="IXT46_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946783.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHLNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNKLFTKNVSNWQQAVDDVIIKEKLA
                     SADVAHVRENMSFFKDSAWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSLIEQIRNEKIRAAYASKAETVAQQMGYSNTSY"
     gene            989..1933
                     /locus_tag="IXT46_000848"
     CDS             989..1933
                     /locus_tag="IXT46_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4946784.1"
                     /translation="MAKRRRRSRGKKIFLIILAILVVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGHDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYRDAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            1949..2728
                     /locus_tag="IXT46_000849"
     CDS             1949..2728
                     /locus_tag="IXT46_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAQ4946785.1"
                     /translation="MEETISLKEIFETLRKHVITILISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQATSTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAPTQPKATNDKTAPSRRSRSRV"
     gene            2742..3440
                     /locus_tag="IXT46_000850"
     CDS             2742..3440
                     /locus_tag="IXT46_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAQ4946786.1"
                     /translation="MHEHRNKKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENMSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3468..4232
                     /locus_tag="IXT46_000851"
     CDS             3468..4232
                     /locus_tag="IXT46_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAQ4946787.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIDRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLQLGKTPVIVHPERNAHFRKDPNHMLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYKQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEIKKKKFGLF"
     gene            4245..6062
                     /locus_tag="IXT46_000852"
     CDS             4245..6062
                     /locus_tag="IXT46_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4946788.1"
                     /translation="MFVLTRRRKIATLVVVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISTGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFGSLSASDVSSILILLFINRQYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIQVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESAHVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAKGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNK"
     gene            6076..7299
                     /locus_tag="IXT46_000853"
     CDS             6076..7299
                     /locus_tag="IXT46_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HAQ4946789.1"
                     /translation="MNKLEKRQIPFSPPDITDLEIKNVVEVLKSGWITTGPKTKKLEK
                     KITKWLGTSKVVCLNSQTAAAETGLRLLGIGENDEVIVPAYTYSASASVVCHIGANLV
                     LIDCQQDSLEMDYDALEAAITEKTKVIIPVDLGGIPCDYDRIFEIVEKKRNLFQPSNE
                     IQKAYGRIIVMADSAHAFGANWHDQMVGNVADLTTFSFHAVKNFTTAEGGALVWKEHD
                     KLDNEAMYHQCQLLSLHGQSKDALTKTQLGAWEYDIVGPWYKCNMTDVTASIGLAQFE
                     RYPNILKRRKNIIKRYDEAFQQLGIEVLMHYTDDYSSSGHLYITRVPNISSEQRNEII
                     IKMAEQGIACNVHYKPLPMFTAYKNMGFDINNYPNAYAHFVNEITLPLHTKLTDEEVE
                     YVINNYSKIVKDLVG"
     gene            7313..8047
                     /locus_tag="IXT46_000854"
     CDS             7313..8047
                     /locus_tag="IXT46_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006443581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAQ4946790.1"
                     /translation="MRKWEDLPKEMQNDEIRYYYDILSKKKFSLVVKRVFDILVSATL
                     LLTLSWLFFILAIVIKIDSPGPVFYRQERITRYGKKFKIYKFRTMVINADKDGTLVTV
                     KNDDRITRVGKVIRKYRLDEISQLINVLVGDMSFVGTRPEVGKYVKSYSPLMLATLLL
                     PAGITSETSILYKDEDKLLHDKNNIDKTYIEKILPSKMYYNLKSISEFSCMNDLKIMC
                     KTIFVIFGKEYHADLEGEREFINQIK"
     gene            8064..8675
                     /locus_tag="IXT46_000855"
     CDS             8064..8675
                     /locus_tag="IXT46_000855"
                     /inference="COORDINATES: protein motif:HMM:NF012792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4946791.1"
                     /translation="MVIEEIKSSDKELINSIVDIHMRTFTNFFLTFMGKKFLELMYRS
                     YTEYNDSGILVAIQNDKPIGFLAYSGDMSGLYKYMIKKRIIPFGFYSCVAFIKKPNIL
                     MRLFRAFLKPSETKRDENYVELASIGVNPKEKSIGVGSMLIDNLKSRIDFSKYEYIAL
                     ETDALNNDVVNNFYKKNEFILERKYSTNEGRIMNEYRFYMEKN"
     gene            8678..9823
                     /locus_tag="IXT46_000856"
     CDS             8678..9823
                     /locus_tag="IXT46_000856"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4946792.1"
                     /translation="MKLLYILNVANKVNNFSKASMMAAKQTGLEFYIAGNWKYKSDEE
                     RKADEVKYGIKIYQVDFYRNPLNLKNIKAYHQIVEIIKNEKIDIIHCNTPIGGVVGRI
                     AGLKCKVKKVIYQAHGFHFYSGAPKINWFIYYPMERWLAHYTDVLITINHEDYTLAQK
                     LRLRKGGKAYYIPGVGIDTNRFMSSTSIRNFRESICKELNIPDTAKIILSVGELNENK
                     NHLSVIHALQKIPLHTDIYYIIAGVGEMRETLQNIANELGLHQRVFLLGYRSDIPKLL
                     AAANIYILPSLREGLNASLMEAMASGLPCIVGNIRGNVDLIEDGKGGFLINPKDEEEI
                     AGAINRLADNKLLCESMGAHNLDKIKDFDLSVVINQINNVYHEIVSK"
     gene            9846..10898
                     /locus_tag="IXT46_000857"
     CDS             9846..10898
                     /locus_tag="IXT46_000857"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4946793.1"
                     /translation="MKKIKIMHLLQSNRFSGAENIVCQIMSLFQNNEKFEMIYVSPDG
                     PIANILNIRGLSYLPLKKFSRKEIDRAVHELNPDIIHAHDFNASVRASRYKKQIILSH
                     LHNNPLWLPKLDIRTIIYSLCSSRFNSVIGVSNSVKEEFRYKQLIKDKFVLLPNTVNT
                     ERIIKMGNEFVEDDIDILYVGRMAEPKNPIGAINVLENVVKKYSKHLRVVMIGEGPLF
                     DEVKMQIQKRNLTDVIELKGFKSNPYKYMKKSKVLLMPSLWEGFGLVSVEAMLLETPV
                     VAYNVGGLKDIIDETNGFLCGSEVELSNSLMKLLNSEELRKKMGENAAISAKKFSNMN
                     RYQGVLEKIYVSAALK"
     gene            11427..12203
                     /locus_tag="IXT46_000858"
     CDS             11427..12203
                     /locus_tag="IXT46_000858"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAQ4946794.1"
                     /translation="MAFQVYLQRVYILSTGVIIGHYAEMGLNRIAYAGLMGDFSFAGL
                     YLATGCLYAFLKYVDLKNWKLLFFIIIEVFLLGAILCVSARTGLVSLFVTMTLYYLFN
                     INRISVPHLLVLIGGIITTPYILVMLMAGRSGQSLLDSSGRLENYMSSLNAFSDKYLI
                     GYGLGLNNLYTLLGVAVPHNFFIQYLLQTGIIGTLIILSGFFKFTYEELKKSGCYKWL
                     FLMIVVGAMFIPDIVSSRFLYAIVVLCMISASERTIKKES"
     gene            12214..12675
                     /locus_tag="IXT46_000859"
     CDS             12214..12675
                     /locus_tag="IXT46_000859"
                     /inference="COORDINATES: protein motif:HMM:NF012360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine acetyltransferase"
                     /protein_id="HAQ4946795.1"
                     /translation="MRRKAEKWADKACRQYRNGQNKMSKISCYILRIIYGCEFYGQVD
                     FSSNAQLVHNGLGCVFHPKTKIGNNCKIYQNVTLGGNGKIINGKETVGAPTLEENVAV
                     FAGACVLGPINIGHDSIIGANAVVTKSVPPYSLVYGNPAIITELKFDYKFD"
     gene            12734..14191
                     /locus_tag="IXT46_000860"
     CDS             12734..14191
                     /locus_tag="IXT46_000860"
                     /inference="COORDINATES: protein motif:HMM:NF024832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HAQ4946796.1"
                     /translation="MGNNIHGKTAKALKWSSLAEIIAKIITPISNMILARLLTPDAFG
                     VVATVTMVISFADMFSDSGFQKFLVQHEFDNEEHMFSSTNVAFTSNLGISLLLWLFIC
                     VFNNKIAHLVGNSGLGLVIIVAGVSLPITSFSSIQSAIFRRNFDYKILCYARIISALI
                     PLVITVPLAIIGLSYWSLVIGSIIGNLVTAAILTKLSEWKPKLFFSKKEFYEMFSFSA
                     WSLVESLGTWLSSYIGTFIVGGILSVYYLGIYKTTMTTVNGIFAIVTSATTTVLFSTL
                     SRLQNSKTEYDKTYLDFIKIVSIFIIPLGIGIYVYRELVTNILLGSQWKEAVPFVGIY
                     GLMSCFTLVLGQYASEYYRGLGKPKANVLMTILHLAVLIPVLIIYSRKGFIELAYGRS
                     FVKIEQIIVFWIILWFGFKFNPFKILKQVWKSCASALLMGVLAKIMLEFCTNYVMQLL
                     SVCLCVILYFFIYSCIFKGKTEIINMVRMFTGKGY"
     gene            14226..15395
                     /locus_tag="IXT46_000861"
     CDS             14226..15395
                     /locus_tag="IXT46_000861"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4946797.1"
                     /translation="MKKVTILIPGMYYGGMERVAFITRQILLKNNYNVSFVTLFDNDA
                     DYQPNFEYLSLKCDIKPSKFGKVINIFKRVYKMKSVKKKLKTDITISFGQSCNLVNVL
                     SKRDDKVYVGIRSYDWLFQYIFHYYVDKFVYKKADAVVSVSQLIKRDAENIFNFNKDK
                     SYFLYNPYDLELINNKSKEKITEIEVPTDKKIIVTVGRLEDQKGLYHLIKAISMLKNK
                     DNVVVYILGHGTKKELLENLIKAYQLQNVIFLLGGQSNPYKYMSRADLYVMPSITEGF
                     PNALVEAMSTETAVLCADCKSGPREILSNRTLDTICENIEYAESGILVCPMTDSRNYS
                     PQYEECDKNLANAIEELIENDNLRNKYAKAAKKRAELYSYDAFEHNLLQIMKTFN"
     gene            15433..16524
                     /locus_tag="IXT46_000862"
     CDS             15433..16524
                     /locus_tag="IXT46_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAQ4946798.1"
                     /translation="MLKKNTSLQNKTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFLFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
     gene            complement(16592..18070)
                     /locus_tag="IXT46_000863"
     CDS             complement(16592..18070)
                     /locus_tag="IXT46_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HAQ4946799.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRVESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(18336..19084)
                     /locus_tag="IXT46_000864"
                     /pseudo
     CDS             complement(18336..19084)
                     /locus_tag="IXT46_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            19227..20177
                     /gene="pfkB"
                     /locus_tag="IXT46_000865"
     CDS             19227..20177
                     /gene="pfkB"
                     /locus_tag="IXT46_000865"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAQ4946800.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQKKQIQTEFIEVPGMTRINVFTQVNQTREE
                     YKLVNQGPEIPQAAVHNFLNQIRALQAEDYLCVSGSLPRGMSPKVLVEISRICQEKEI
                     HLIIDSSDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENV
                     LLSLGEKGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLVGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            20159..21622
                     /locus_tag="IXT46_000866"
     CDS             20159..21622
                     /locus_tag="IXT46_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4946801.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTILADNEAVDTLESETISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMLKTVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     SGGTGFLVGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVVFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPINKAAYVTGTALLAQGN
                     TTFMAGVSVACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEEGRAGGLS"
     gene            21619..22077
                     /locus_tag="IXT46_000867"
     CDS             21619..22077
                     /locus_tag="IXT46_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAQ4946802.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIAHDEKEVYRK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIVTLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            22074..23048
                     /gene="lacD"
                     /locus_tag="IXT46_000868"
     CDS             22074..23048
                     /gene="lacD"
                     /locus_tag="IXT46_000868"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAQ4946803.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPECGLPAAALREKECGLLLAYEKTGYDTKMPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECDAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLKETATPVYVDR"
     gene            complement(23227..24177)
                     /gene="yidC"
                     /locus_tag="IXT46_000869"
     CDS             complement(23227..24177)
                     /gene="yidC"
                     /locus_tag="IXT46_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAQ4946804.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(24615..24890)
                     /locus_tag="IXT46_000870"
     CDS             complement(24615..24890)
                     /locus_tag="IXT46_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAQ4946805.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            24998..25762
                     /locus_tag="IXT46_000871"
     CDS             24998..25762
                     /locus_tag="IXT46_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAQ4946806.1"
                     /translation="MKEIQSAKNPKIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            25885..26388
                     /locus_tag="IXT46_000872"
     CDS             25885..26388
                     /locus_tag="IXT46_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4946807.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            26796..27443
                     /locus_tag="IXT46_000873"
     CDS             26796..27443
                     /locus_tag="IXT46_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HAQ4946808.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALATEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMIYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            27606..28874
                     /locus_tag="IXT46_000874"
     CDS             27606..28874
                     /locus_tag="IXT46_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAQ4946809.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(28901..30100)
                     /locus_tag="IXT46_000875"
     CDS             complement(28901..30100)
                     /locus_tag="IXT46_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAQ4946810.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYAWQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(30219..31526)
                     /locus_tag="IXT46_000876"
     CDS             complement(30219..31526)
                     /locus_tag="IXT46_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAQ4946811.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            31997..33115
                     /locus_tag="IXT46_000877"
     CDS             31997..33115
                     /locus_tag="IXT46_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946812.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            33499..33819
                     /locus_tag="IXT46_000878"
     CDS             33499..33819
                     /locus_tag="IXT46_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946813.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            34271..34471
                     /locus_tag="IXT46_000879"
     CDS             34271..34471
                     /locus_tag="IXT46_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4946814.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            34618..37407
                     /locus_tag="IXT46_000880"
     CDS             34618..37407
                     /locus_tag="IXT46_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4946815.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFIYVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGTGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMTTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            37454..37981
                     /locus_tag="IXT46_000881"
     CDS             37454..37981
                     /locus_tag="IXT46_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4946816.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            38002..39192
                     /locus_tag="IXT46_000882"
     CDS             38002..39192
                     /locus_tag="IXT46_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4946817.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFLKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            39232..40530
                     /gene="asnS"
                     /locus_tag="IXT46_000883"
     CDS             39232..40530
                     /gene="asnS"
                     /locus_tag="IXT46_000883"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAQ4946818.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            41707..42381
                     /locus_tag="IXT46_000884"
     CDS             41707..42381
                     /locus_tag="IXT46_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4946819.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            42378..42719
                     /locus_tag="IXT46_000885"
     CDS             42378..42719
                     /locus_tag="IXT46_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946820.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            42749..43108
                     /locus_tag="IXT46_000886"
     CDS             42749..43108
                     /locus_tag="IXT46_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAQ4946821.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            43311..43490
                     /locus_tag="IXT46_000887"
                     /pseudo
     CDS             43311..43490
                     /locus_tag="IXT46_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308695.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
     gene            43632..45713
                     /gene="cadA"
                     /locus_tag="IXT46_000888"
     CDS             43632..45713
                     /gene="cadA"
                     /locus_tag="IXT46_000888"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAQ4946822.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            46024..47490
                     /locus_tag="IXT46_000889"
     CDS             46024..47490
                     /locus_tag="IXT46_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4946823.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            48105..48644
                     /locus_tag="IXT46_000890"
     CDS             48105..48644
                     /locus_tag="IXT46_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HAQ4946824.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            48718..49158
                     /locus_tag="IXT46_000891"
     CDS             48718..49158
                     /locus_tag="IXT46_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAQ4946825.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            49171..49380
                     /gene="copZ"
                     /locus_tag="IXT46_000892"
     CDS             49171..49380
                     /gene="copZ"
                     /locus_tag="IXT46_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAQ4946826.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            49380..51566
                     /locus_tag="IXT46_000893"
     CDS             49380..51566
                     /locus_tag="IXT46_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAQ4946827.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            51586..53757
                     /gene="copB"
                     /locus_tag="IXT46_000894"
     CDS             51586..53757
                     /gene="copB"
                     /locus_tag="IXT46_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAQ4946828.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT        17888 a         8876 c        11144 g        15861 t
ORIGIN      
        1 tccctagtca agaaaactgt ttgtggtatg attatatagg gaaaacctgt ttataaatat
       61 ttctatgaat atattagttt aattatgctt ttaaaataaa aagcgctcat tctgatgtga
      121 atgaatcaca tctttattta tctatcatca atatttagga gtgaatctat ggaaaagccg
      181 ttcgtcaagt tattggctac tgtggcggta ggcacaggcg ctattgtgat ttgcttgttt
      241 ggataccatc tcaataatca gcggcaacat catcaacgga tcaattacgc agaatctgcc
      301 atcaccaatc aaaaagacac cgtgacctct ttatcaaaag aagtagataa gctgtacagt
      361 acaaaagaaa aaattttcct aaatcctgaa ataacagaag aaacagtttc aaatttgtca
      421 cataaactat cttctatcaa actttcagca gatgattatg acatcaagga atcagaatta
      481 cctaaagaag ctgctgcgat ccaagaagaa aagaaagcag tcttaacaca gttagaggat
      541 gcagaatcaa aactgaagat ccaaacggct gtcaataaat tatttactaa aaacgtatca
      601 aactggcagc aagctgtgga tgatgtcatc atcaaagaaa agttggcaag tgcagatgtc
      661 gcccatgtac gtgaaaatat gagctttttt aaggatagtg cttggaaaac ggtcgttatg
      721 caatatctag gattcgctga tacccaaatt gcacaagtca cgcaactaga tcagctattc
      781 gatacgatgc tgaaagacgg tcaagtaaca gctactgcta cttacgatca atatttgacc
      841 gcactcagtc tcatcgaaca gatccggaat gaaaaaataa gagccgcata cgcgtcaaaa
      901 gcagaaacag tcgctcagca aatgggctat agcaatacga gctattaata agcgagaatt
      961 caagcaaggc tagcaaacgg aggaaactat ggcaaaacga agaagaagat caagagggaa
     1021 aaagatattt ctaattattt tagcaattct tgtcgtatta gtattagcaa tcgtaggagt
     1081 aggagcaaaa ttatatctag atctctcaca ttctattgaa aaaacttacg aatcagtgga
     1141 acgaacccaa ggagaacgaa caaaaccagt tgatctggac aaacaagaat ctttctctgt
     1201 tctattgatg gggattgata cgggagattt aggtcgggtc gatcaaggaa gatcagatac
     1261 gatgatggtt gccacagtca gtcctgaaga caaacagaca acgattgtca gcattcctcg
     1321 tgatacgtat gtcgacatcg ttggacatga cacaaaagac aagatcaacc acgcttacgc
     1381 attcggcgga gctgccatgg cgatggatac cgtacaaaaa tatgtagaca tcccaatcga
     1441 tcactatgtt tcaatcaata tgaaaggtct aaaagaactc gttgatgcag ttggtggtat
     1501 cgaagtcaat aatgacctca ccttctcaca agatggctat gattttacga tcggtaaaat
     1561 cacattgaac ggggatcagg cattgtctta ttctcgtatg cgttatgaag atccaaatgg
     1621 tgactacggc agacaagaac gtcaaagaaa gatcgtagaa ggtgtagcga aaaaagtgtt
     1681 gagtctgaac ggtgtaagca actatcaatc cgttttgaat gctctagagt cgaatatgaa
     1741 aacagacatg agctttgatg aaatgaaaaa gattgcttta gattatcggg atgcatttgg
     1801 tacgatcaag caagatcagc tgcaaggaga aggcttcatg caagacaata tctcatacca
     1861 aaaagtcagc gatcaagaac ttgatcgtgt gaaaaaagaa ttaaaagatc aaatgaatct
     1921 agagaataaa taggaaagtg gagaaaaaat ggaagagaca atcagcttga aagaaatttt
     1981 tgaaacatta cgcaaacacg tgataacaat cctcatctca atgtttgctg gcttggccat
     2041 ctcaggcatc gtgacgtttt tcatcttgac gccaaaatac agctcacaag cccaattgat
     2101 cgtgacactg ccgcaatcag atactgcaaa tgtcaatgat gtcaatacga acctgcaaat
     2161 gatcaatacg tataaggata tgatcgtcag tgatctagta ctaaatgaag tcaaagatcg
     2221 tttagaaaca gaagacaatg taaaaatgac tgctggacaa atcaaagatg ccatctccgt
     2281 caatcagtca caaaattcac aaatgttctc gatccaagca acaagcacaa atgcagtgac
     2341 ggctcaacaa atcgctaata caacgtcaca agtattccaa gagaacgcca aagacgtgat
     2401 gaatgtcgat aaaatctcga tcatctcagg tgcagttgcc aatacgacac ctgtttcgcc
     2461 aaataataaa ttgaatctag tgattggctt agtgttagga atgatggtag gcgtaggtct
     2521 agctttctta tttgaattac tcgaccggac agtaaaagat gaaaaatatg tgacggatac
     2581 attgggcttc ccgatcttag ggactgtacc agaaatgtca gcgaaagaat tgaatgctgg
     2641 tatccgtaaa aaaggaccag ctccgacaca accaaaagct acaaacgata aaacagcgcc
     2701 atcacgcaga agccgctcaa gagtctagga ggaaagaaaa attgcacgaa cacagaaaca
     2761 aaaaagcagc ccaaactcat gcagtcagtt tggtcacact cacaaacccc tcttcaccaa
     2821 tcgctgaaca atatcgtacg attcggacga atatccagtt tgcctccgca gctggtcagc
     2881 aaattaaaac gattgttgtg acttcatcag gacctggaga agggaaatcg accactgcag
     2941 caaacattgc cgttgttttt gccaaatctg gtcaacgggt gctgctagtc gatgcagact
     3001 tacgtaagcc cgtcatctat aaaacgttca agttgaacaa cgcaagcgga ttaagtaccg
     3061 ttcttagttc atcaggaagt gtagcagatg agatccaacg aacaccagtc gagaatttgt
     3121 cgattctgcc aagtggacct aaaccaccaa atccatcaga actactaagt tcgccaagaa
     3181 tggatcagat tttagcagaa gcaagacaac tatttgatgt agtgatcttc gacatgccgc
     3241 cagtagttgc cgtaacagat gcacagatca tgtcttccaa aacggatggc accttattgg
     3301 tcgtacgtga aaatatgtca cggaaagaat cattgactaa agcaaaagaa ttgctggata
     3361 tggtacaagc gcgagtcctt ggtgttgtat acaatggggc agaacacagc aaagatgctg
     3421 gctattacta cgggaattaa gaaataaaaa gagaggagac aagagaaatg atcgatctac
     3481 attgccatat cctgccagga atcgatgacg gagcagaaaa catagatgcc agtatcgcca
     3541 tggctgaaaa agcgattcaa caagggatca cacatatttt atgcacaccc catcataata
     3601 atggaaaata cagcaatgaa aaatcacaag tcatttctct agtcgcttcg ttacaagcag
     3661 aattagagaa aagacaattg cctttgacgt tattggaagg acaagaagta cgtattaccg
     3721 gaacactgat cgaagacatc gaccgagatg aaattttatt tacagattta gatgatacat
     3781 atcttctaat cgaatttccg acactggaag tgccgttata tgcagaacag ctcttttttg
     3841 agttgttaca actaggaaag acaccagtga tcgtccatcc agaacgcaac gcgcattttc
     3901 gtaaagaccc gaatcatatg ctgccattcc tagatatggg atgcttggcc caactcaccg
     3961 caccaagtta tgtcggtgta tttggaaaag acatccagaa aacagccaaa atgatggtca
     4021 aacataatct tgtgcagatg gctgcttctg atgcccatgg ggtctctaag cgcacctttt
     4081 acttaaaaga gtgctataag cagattgcca aggactttgg taaggaaaaa gtagtacaga
     4141 tgaaacaagt cgcaaaggat ctgatcaacg gggatgaaat cagttatcca gtctatgaag
     4201 agataaaaaa gaagaagttt ggtttatttt agggggagtg taaggtgttt gtattaacaa
     4261 gaagaagaaa aattgccaca ttggttgttg tggacagttt gttattgatc gctgcaaata
     4321 ttgcagcagc taaattcatg aagccgtttg tagctatacc aatggacctt attttaatct
     4381 ctaccggttt gtcgattggt ttttatttat tttatggtag tttattcaaa gttttcactc
     4441 ggatcaatcg ctatacaaat ttaagagaga tcattgcaat ttttggttca ctatctgcaa
     4501 gtgacgtctc aagtatcctc atactgctgt tcattaatcg gcaatacagt ttacggttag
     4561 ttatctttgc ttatctgctt tcgctcttat tgatcatcgg tagccgattg atctggcgta
     4621 tctacatcga aacaaaaaat atgagatatg tatcagcgga ttctgctaaa aatacattga
     4681 tcgttggtgc tggcgaaggc gggcgtattt tatacaacag ctttctggga tccaaaacgg
     4741 ctcaagatat ccaagttgtc ggatttgtag atgatgatcc gaataaaaga aatacgtatc
     4801 tttcaggaaa aaaagtatta ggtgcattaa aagatattcc ggaattgatt gaaaaatatg
     4861 acattcaaat ggtaacgatc gctatccctt ccttatcaag aaaaaaatta cgaagaatct
     4921 tcgagttagt cgaatccgct cacgtgaaag tcaacacgat gccttctata gaagaacttg
     4981 cttcaggaaa aattagcgta tcaaaattaa aaacaattga cgtagtggat ttactgggaa
     5041 gagatgaggt aaagctggat attgaatcca tcaaagatca gatcacagac aaagtcattc
     5101 ttgtcaccgg cgcaggagga tcgatcggtt cagaaatctg tcggcaaatc attcaattca
     5161 atcctgcaaa gctattgctt ttaggacatg gggagaactc gatctacttg attgaccgtg
     5221 agttacgcac gcatcatcaa aattgtccta cagaaatcgt accgatcatc gcagatatcc
     5281 aagatcgcga gaaaatcaat gagatcatgg aacaatatca tccagatatc gtctaccatg
     5341 cagctgctca taaacatgta ccactgatgg aatataatcc aaaagaagca gtcaaaaaca
     5401 atattttcgg tacaaaaaat gtagcagaag cagctaaagc agcaaaagtg aaaaacttcg
     5461 tcatggtatc gacagataaa gctaacaatc ctccaaatgt catgggttca acaaaacgaa
     5521 tcgctgaaat gatcgtgact ggattgaatg aagaaggctg tacgaaattc tcagctgtca
     5581 gatttgggaa tgtccttggt tctcgcggta gtgtgattcc agtattcaga gaacaaattg
     5641 ctaaaggtgg tccaatcact gtaacagact ttcgtatgac ccgatacttc atgacgattc
     5701 ctgaagctag tcgtttagtt attcaatctg gcgcattagc aaaaggtggc gaaattttta
     5761 ttctagatat gagtgaacca gtgaagattg tagacctagc caaaaacatg atccgattga
     5821 gcgggtatag cgaagacgaa atcgaaatca ttgaaacagg tatccgtcca ggggaaaaac
     5881 tatatgaaga actactgttg gataaggaaa gaaatgatga agcagtttat gagaaaatct
     5941 ttgtaggaaa catcaaaggt tactcaatac aaaaagtgat ggattttgtc aagagcctgc
     6001 cgcaagacga tgaacaattg gctaaagata tcgtcacttt tgcaaatgct tcgaataaat
     6061 aggggggaaa tataaatgaa taaattagaa aaacgtcaga taccattttc accgccagat
     6121 attactgatt tagaaataaa aaacgttgta gaagtattaa aatctggatg gataactacg
     6181 ggaccaaaga caaaaaaatt agaaaaaaaa attacaaagt ggttaggaac ttctaaagta
     6241 gtttgtttaa attcacaaac tgctgctgca gaaacagggt tacgtttgct gggaatagga
     6301 gaaaatgatg aggttatcgt cccagcttat acttattctg ccagtgcatc ggttgtatgc
     6361 cacataggcg cgaacctagt attaatagac tgtcaacaag attctttgga gatggattac
     6421 gatgcattag aagcagcaat tacggagaag acaaaagtga ttattcctgt tgatcttggt
     6481 ggtatacctt gtgactacga ccgtattttt gagattgtgg agaaaaaaag aaatttattt
     6541 caacctagta atgagattca gaaagcttat ggtcgtataa ttgttatggc agattctgct
     6601 catgcatttg gagctaattg gcatgatcag atggttggta atgttgctga cttgacaaca
     6661 ttttcatttc atgctgttaa gaattttaca actgcagaag gtggagcttt agtatggaaa
     6721 gagcacgaca aactagataa tgaggcaatg tatcatcagt gccagctgct ttctttgcat
     6781 ggacagtcaa aagatgcact tactaaaaca cagttgggtg catgggaata tgatattgtg
     6841 ggtccatggt ataaatgtaa tatgactgat gttactgcat caattgggtt ggcacaattt
     6901 gaacgctatc ctaatattct gaaaagaaga aagaatataa ttaagaggta tgatgaagcc
     6961 tttcaacaac taggaattga agttcttatg cattatacgg atgattatag ttcttcaggc
     7021 catttatata ttactagagt acctaacatt agttctgagc aaagaaatga aataattata
     7081 aaaatggcag aacaagggat tgcttgcaac gttcactata aaccacttcc aatgtttaca
     7141 gcatataaaa atatggggtt tgatattaat aactatccta atgcctatgc tcattttgta
     7201 aatgagatta cattaccatt gcacacgaaa cttacagatg aagaagtaga atacgtaatt
     7261 aataactata gtaagattgt aaaggatttg gttggatgat aggagaggca aaatgagaaa
     7321 gtgggaagat ttgccaaaag aaatgcagaa tgatgaaata cggtattatt atgatatcct
     7381 cagtaaaaaa aaattcagct tagtggtaaa aagagtattt gatattttag tgtctgcaac
     7441 tttgttactg acactttcat ggttattttt tattcttgca atagtgataa aaattgattc
     7501 tcctggacct gtattttata gacaagaacg tattactcgt tatggaaaaa aatttaaaat
     7561 ttataagttt cgtactatgg taataaatgc agataaagat ggcactcttg ttactgtgaa
     7621 aaatgatgat cgtattacaa gagtaggaaa ggtaatccgt aaatatagat tagatgaaat
     7681 tagtcagcta attaacgttt tggtcggaga tatgtctttt gtaggaacca gaccagaagt
     7741 tggaaaatat gtaaagtcgt attcaccatt aatgttagcc acattattat taccagccgg
     7801 gattacatca gaaactagta ttttatacaa agatgaagat aaattgttgc atgataaaaa
     7861 taacatcgac aaaacttata tagaaaaaat tcttcccagt aaaatgtatt acaatttgaa
     7921 aagtatcagt gaatttagtt gtatgaatga tttgaaaata atgtgtaaaa ctatttttgt
     7981 tatatttggt aaagaatatc acgccgactt agaaggtgaa cgagagttta ttaatcagat
     8041 aaaatgaatg gaggataaga gttttggtga ttgaagagat aaaaagttcg gataaagagt
     8101 taattaattc gattgtcgat attcatatga gaacatttac aaattttttt ttgactttca
     8161 tgggaaaaaa gtttttggaa ttgatgtatc gttcttacac agaatataat gattctggta
     8221 tattggttgc tattcaaaat gataagccaa taggatttct tgcatattct ggagatatga
     8281 gtggtttata taagtatatg ataaagaaaa gaataatacc gtttggattt tatagttgtg
     8341 tagcctttat aaagaaaccc aatatcctta tgaggctttt tagagctttt ctaaaaccaa
     8401 gcgaaacaaa acgtgatgaa aattatgtgg aattagcatc cattggagtt aatccgaaag
     8461 agaaatcgat aggagtaggt tccatgctta tagataactt aaagagtaga attgattttt
     8521 caaaatatga atatattgca ctagaaacag atgcattaaa taatgatgtt gtgaataatt
     8581 tttataaaaa gaatgagttc attttagaac gtaaatattc tactaatgaa ggaagaatta
     8641 tgaatgaata tcggttttat atggagaaga attaattatg aaattattgt atattttaaa
     8701 tgtagctaat aaagtaaata acttttctaa agctagtatg atggcagcta aacaaacggg
     8761 tttagaattt tatatagctg gtaactggaa atacaaatcc gatgaggaaa gaaaagctga
     8821 tgaagtgaaa tatggaataa aaatatacca agttgatttt tatagaaacc cactaaattt
     8881 aaaaaatata aaagcttatc atcagattgt agagattata aaaaatgaaa aaatagatat
     8941 tatccattgt aatacaccta ttggaggtgt tgtcggacgg attgctggtc ttaaatgtaa
     9001 agtcaaaaaa gtaatttacc aggcacatgg atttcatttt tattcaggtg ctcctaaaat
     9061 aaattggttt atatattatc ctatggaacg ttggctagct cattatacag atgttttgat
     9121 tacaataaat catgaggatt atactttagc tcaaaaactt cgtcttagga aaggtggaaa
     9181 agcttattat attccaggtg tgggtataga tacaaatagg tttatgtctt ccacatcaat
     9241 aaggaatttt agagaaagta tatgtaaaga acttaatata cctgatacag caaaaatcat
     9301 tttatctgta ggagagctaa atgagaataa aaaccattta tcagtaatac atgcattaca
     9361 aaaaattccg ctgcatacag atatctatta tattatcgct ggggtaggag aaatgaggga
     9421 gacactacaa aatattgcta atgaattagg attacatcag cgagtttttt tactaggata
     9481 tagaagtgat atacccaaat tattagctgc tgcaaacata tatattctac cctcattaag
     9541 ggaaggcctc aacgcctctt taatggaagc gatggctagt ggtttaccat gtattgtcgg
     9601 taatataaga ggaaatgtag atcttataga agatggtaag ggtggatttc taatcaatcc
     9661 taaagacgaa gaagaaattg ctggtgcgat aaatagattg gctgataaca aattattgtg
     9721 tgaatctatg ggggcacata atttagacaa gataaaagat tttgatttat cagttgtgat
     9781 aaaccaaata aataatgttt accatgaaat tgtaagtaaa taattgaatt gaaagtgata
     9841 ttaatatgaa aaaaataaaa attatgcatt tgttgcaaag taatagattt tctggcgctg
     9901 aaaatattgt ttgtcaaata atgagtttat ttcaaaataa cgaaaaattt gagatgattt
     9961 acgttagccc agatggtcct atagcaaata ttttaaatat tagaggttta agttacttac
    10021 cattaaaaaa attttcgaga aaagaaattg acagagccgt acatgaatta aacccagata
    10081 taattcatgc tcatgatttt aatgctagtg taagagcaag tagatataag aagcaaatca
    10141 tcctttccca tttgcacaat aatcccttgt ggttacctaa actagacata agaactatta
    10201 tatattcttt atgttcgtct aggtttaatt cagtaattgg tgtttcgaat tccgttaagg
    10261 aagaatttcg ttacaaacaa ttaataaaag ataaatttgt gttgttacct aacactgtaa
    10321 atactgaaag aattataaaa atggggaatg aatttgttga agatgatatt gatattttat
    10381 atgtaggacg catggcagaa cctaaaaatc caataggtgc aattaatgtt ttagaaaatg
    10441 tagtaaaaaa atattcaaaa catttacgtg tcgtgatgat tggtgaagga ccattatttg
    10501 atgaagttaa gatgcaaata caaaaaagaa acttaacaga tgttattgag ttaaagggat
    10561 tcaaaagtaa tccctataag tacatgaaga aatctaaagt tctattaatg ccatctcttt
    10621 gggaagggtt tggcctagta tcagtagagg caatgttgtt agagacgcct gttgtagctt
    10681 ataacgtagg aggattgaag gatattatcg atgagacaaa tggatttctg tgtggtagtg
    10741 aagttgaatt atctaattca ctaatgaagc tattaaattc agaagaactt agaaaaaaaa
    10801 tgggagaaaa tgctgctatt agtgcaaaga aattttctaa tatgaatcgt tatcaaggag
    10861 tattagaaaa aatttatgta tctgcagctt taaaataaaa tatgaattat aaaaatagag
    10921 atcaattagt tttacgaaaa ataataccca ttagtatttt gtttcaatca ggaatgattt
    10981 tttattcact gatgccctca atagcaattg cagttgtttc tttttttatg tttttgtatt
    11041 atatgtggtg cttaaaaaag tatttttgtt tagcagatag cttattgtta acatcaattc
    11101 ttttcattcc aacatcaact atatctatat taggaactag ttattctagc ttaccattga
    11161 cgtggcataa tctaataata ataattttga tgttatatat tattatagaa ggaacattaa
    11221 atcgttcata cttgattatt ttatttttat ttatttgttt tggaatatcg acgtctatgt
    11281 tcttaccttt tttaatagat gcattaaagc aattaatgac tatttcgttg tttatctgta
    11341 gttttttaat aggaaaacgt tttaaaatgt atagcaaaaa cttaactatg attgggtgga
    11401 atttctattt cataggagta gtatctatgg cgtttcaggt atatttgcaa cgagtatata
    11461 ttttatctac tggtgtaata ataggccatt atgcagaaat gggtttaaat agaattgcat
    11521 atgcaggttt gatgggagat tttagttttg cagggttata tcttgctaca ggctgtctat
    11581 atgcttttct aaaatatgtg gatttaaaaa attggaaatt attattcttt ataataatag
    11641 aagtattttt attaggtgca attttatgtg ttagtgcaag aacagggtta gtttccttgt
    11701 ttgtcacaat gacattgtat tatctattta atataaatag aattagtgtt cctcatcttt
    11761 tagttctaat aggtggaatc ataactacac cttatatact agtaatgtta atggcaggtc
    11821 gttctggaca aagtcttttg gattcttcag gcagattaga aaactatatg tcctctttaa
    11881 atgcttttag tgataaatac ttaataggat atggattagg attaaataat ttatacacgc
    11941 tactaggtgt agcagtacca cataattttt ttattcaata tttattacag acaggaatta
    12001 ttggtacgct aattatttta agtggcttct ttaaatttac gtatgaagaa ttaaagaaat
    12061 caggttgcta taaatggtta tttttgatga tagtagtggg agcaatgttt ataccggata
    12121 ttgtatcttc gcgttttctt tacgcaatag ttgttttgtg tatgatttct gcatcagaaa
    12181 gaactataaa aaaagaaagt tgaggtagaa aaaatgagaa gaaaagcaga gaaatgggca
    12241 gataaagctt gtagacaata caggaatggt caaaataaaa tgtcaaaaat atcctgctat
    12301 attttaagga ttatttatgg atgtgaattc tacggacagg tagattttag ctctaatgct
    12361 caactagtcc ataatggtct tggttgtgta ttccacccta aaacaaaaat cggtaataat
    12421 tgtaaaatat atcaaaatgt gactttgggt ggaaatggca aaataataaa tggaaaagaa
    12481 actgttgggg caccaacgct agaggaaaat gtggctgttt tcgctggtgc atgtgtttta
    12541 ggaccaatta atatcggaca tgattcaatc ataggtgcaa atgctgtagt tacaaaaagt
    12601 gttccaccat atagcttagt atatggaaat ccagcaatca taacagagtt gaaatttgat
    12661 tataaatttg attaaaaagt aatgtttaat atgcgaaagg ttgctatatt tatttagcaa
    12721 aatggggtaa taaatgggaa ataatattca tggaaagaca gcaaaagctt taaaatggtc
    12781 atccttagct gaaataattg caaagattat aactccaatt tcgaatatga ttttagctag
    12841 attattgact ccagatgctt ttggagtagt agccactgta actatggtta ttagtttcgc
    12901 tgatatgttt agtgattcag gatttcaaaa atttttagta cagcatgaat ttgataatga
    12961 agaacacatg ttttcatcaa caaatgtagc ttttactagt aacttaggta tttctttatt
    13021 attatggtta tttatttgtg tgtttaataa taaaatagcg cacttagttg gaaattctgg
    13081 acttggatta gtaattatag tagctggagt ttctcttcca attacttctt tttccagtat
    13141 acaatcggca atttttagac gaaattttga ttacaaaatt ttgtgttatg ctagaataat
    13201 atctgcattg atacctttag ttattacagt accgttggcg ataattggac taagttattg
    13261 gtcactagta attggatcta taataggaaa tttagttaca gctgcaatat taactaagtt
    13321 atcagagtgg aaaccaaaac tttttttttc aaaaaaagaa ttttacgaaa tgttttcctt
    13381 tagtgcgtgg tcactagtgg aatcattagg tacatggttg tcatcttata taggtacttt
    13441 tatcgtagga ggcattttaa gcgtatacta tttgggaata tacaaaacta caatgacaac
    13501 ggttaatggt atttttgcaa ttgtaacttc agcaacaaca actgtattat tttcaacatt
    13561 atctcgttta caaaatagta aaacggagta tgataagaca tatttagatt ttattaaaat
    13621 tgtttccatt tttattattc ctctgggtat aggtatatat gtatataggg aactagtaac
    13681 aaatattcta ctcgggagtc aatggaaaga ggctgtacca tttgttggga tatatggatt
    13741 aatgagctgt tttactcttg tcttgggaca atatgcctct gagtactatc gtggtttagg
    13801 aaaaccaaaa gcaaatgttc ttatgactat cctacattta gcagtattaa ttccagttct
    13861 aataatctat tcaaggaaag ggtttataga actagcatat ggtagatctt tcgttaagat
    13921 agagcagatt atagtctttt ggattatttt atggtttggt tttaagttta atccatttaa
    13981 aattttaaag caggtttgga aatcttgtgc tagtgcattg ctaatgggag ttctagcaaa
    14041 aattatgttg gaattctgta ctaattatgt tatgcaatta ctttcagtgt gtctttgtgt
    14101 aattctatat ttttttatat atagttgtat atttaaagga aaaacagaaa taattaatat
    14161 ggttagaatg tttactggta aaggatatta agagagattt ttatggcaag gttgtgatta
    14221 ggaaaatgaa aaaagtaaca attttaattc ctggaatgta ttatggtgga atggaaagag
    14281 tagcttttat aacgcgtcaa atacttttga aaaataatta taatgtatca tttgtaactc
    14341 tttttgataa cgatgcagat tatcagccaa attttgaata tttatcatta aaatgtgata
    14401 taaagccatc aaaatttggt aaagtaatta acatttttaa aagagtttat aaaatgaaaa
    14461 gtgtcaaaaa aaaattgaaa acggatataa ctatatcttt tggacaaagt tgtaatttag
    14521 taaatgtttt atcaaagaga gatgataaag tatatgttgg aatccggtcc tatgactggc
    14581 tatttcaata tatattccat tactatgtag ataaatttgt atataagaaa gcagatgctg
    14641 ttgtgtctgt cagtcagtta attaaacgtg atgctgaaaa tattttcaat tttaataagg
    14701 ataaaagcta ttttttatat aatccatatg atttagagtt gataaataat aagagtaaag
    14761 aaaaaattac agaaatagag gttccaacag acaaaaaaat tatagtgacg gttggtcgat
    14821 tagaagatca aaaaggttta tatcatctaa ttaaagctat atctatgtta aagaacaaag
    14881 ataatgttgt tgtgtacatc ttaggacatg ggacaaaaaa agaattatta gaaaatttaa
    14941 taaaagcata tcaactacaa aacgtaatat ttttgctagg tggccaatca aatccttata
    15001 aatacatgtc acgtgcagat ttatatgtca tgccatctat aactgaaggt tttcctaatg
    15061 cattagttga agcaatgtct acagaaactg ctgtcttatg tgcagattgc aaatctgggc
    15121 caagagaaat attatcgaat agaacgctag acacgatttg tgaaaatata gaatatgctg
    15181 aatcaggcat attagtatgt ccaatgacag acagtagaaa ttattcgccc caatatgaag
    15241 aatgtgataa aaatttagcg aatgctatag aagaattgat tgaaaacgat aatttgagga
    15301 ataagtatgc aaaagcagca aaaaagagag cagaactata tagttatgat gcctttgaac
    15361 ataacttgtt gcaaattatg aagacattta attaattcat atgatgaaat aaaaataagg
    15421 gagtataact agatgctgaa aaaaaataca tctttacaga ataaaacaat attaataact
    15481 ggcgcagccg gttttattgg atcaaatttg gttcttgagt tattacgtac tcagtcatca
    15541 ataaaaatca ttggcattga caatatgaat gattactatg atgtctctat taagaactat
    15601 agattatcag agatagaaac ggaggcaaag aaccatccag gatctacttg gaattttatc
    15661 aaaggttcta ttgctgataa agcaacaatt gatttcctct ttgataatta taaaccaagt
    15721 atcgtggtga atttagcagc tcaggcagga gtccgttatt caattactaa tccagatatg
    15781 tatatcgaat ctaacataat aggattctat aatattcttg aagcttgtcg tcattcatat
    15841 gataatggag aatctggtgt ggaacattta gtgtatgcct catcgtcttc cgtttatggt
    15901 actaataaga aaattcctta ttctacagag gataaagtag acaatcaagt atcgttgtat
    15961 gcagcaacta agaaaagtaa tgaatcaatg gcacatgcat attctaaact ttacaatatt
    16021 ccgtctacag ggctacgttt ctttacagta tatggtcctg ctggtcgtcc agatatggct
    16081 tattttggtt ttactgataa acttcgtgct ggtgataata tccaaatatt caattatggg
    16141 aattgcaagc gtgactttac ctatatagat gatattgttg aaggagtaaa gagggttatg
    16201 cagtgcgctc cagagaaaat tgatggggaa gatgggctac caatcccacc atatcatatt
    16261 tataatattg gtaacaatac gccggaaaac ctactagatt ttgtagatat tctacaacaa
    16321 gagctaattg cagcaggggt gctaccagaa gattacgact ttgaatctca taccgaacta
    16381 gttccaatgc aaccaggaga tgtgccagtt acttatgcag atactagtgc gttagaacga
    16441 gattttgaat ttaaaccaag tacaagtttg cgtgacgggc ttcgtaaatt tgcgcagtgg
    16501 tataagtctt tttatgaagt ataattgtat ttttttactt ataaaagttt atagaaacac
    16561 ctcagacact acaaatctga ggtgttattt tttaatctcg ttgaaataaa tctctggtat
    16621 atactttttc ttttacatca tcaagattac tatcgtaacg attagcaata atactgtgac
    16681 tgatattttt aaaatcatct aaattattta ttacttttga accaaaaaat gtagtgttat
    16741 tttcaagtgt tggttcataa attacaatag ttgccccctt tgctttaatt cgcttcataa
    16801 ctccttgaat agatgactga cggaagttgt ctgaattact cttcattgta agacggtata
    16861 cacctatgac tacctctttt tctttttctg cattccacga actgttagcc tcatacgtgc
    16921 cagcaagttc taacactcga tctgctataa agtcttttct tgtacgatta ctatcgacaa
    16981 ttgcacttat catattctga ggaacatcgt tatagttagt gagaagttgt tttgtatctt
    17041 tcggtaaaca atagcctcca tatccaaaag atggattatt ataatgtgtg ccaattcttg
    17101 gatctaagca aaccccgtga atgatttctt gtgtatttag tcctttcatt tctgcataag
    17161 tatccagctc attgaagtaa gatactcgaa gtgcaaggta agtattagcg aataatttaa
    17221 ctgcttcagc ttctgtgaat cccatgaaaa gagtttcgat atcttttttg attgctcctt
    17281 cttggagtaa atctgcaaaa gtgtgagagg cttctcgtaa agttttgtca gtttggtccg
    17341 tgccgacaat aattcgcgaa ggatatagat tgtcatataa tgccttagat tctctgagaa
    17401 attctgggct gaatagaata tttttagtat tgtatttttt acgaatactt tcggtatagc
    17461 ctacgggtac cgtcgacttg atgaccatta ttgcctttgg attgacttct aacaccaatt
    17521 tgattactga ctctacagca gaagtatcaa aataattttg tttactatca taatttgttg
    17581 gagcagcaat gacaacaaaa tcggcttctc tataggcggc tgcaccatca gtcgttgcaa
    17641 ttaaattaag atttttttca gctagatatt tttcaatgta atcgtcttgt attggagatt
    17701 tcttattgtt aatttgtttt actttttcag gaagaatgtc tactgctgtt acctgattgt
    17761 gctgggcaag aagagtagca atggaaagac ctacgtaacc agtaccggct acagcaatat
    17821 tcttcgactg atgttttgtt ctgtttgatt tatttgattc atttataaat agatctgttg
    17881 gttcaaaatt tagaacttct gctaatgatt ctaattgttg tattgacggg ataaaatcga
    17941 gagattctac tcgactaatt aaggcacggt tgataccagt agctactgca agttgttgtt
    18001 gtgtcatttt cagagatttt ctagaatcaa taatgatttg agctaaacgt ttttgagata
    18061 actttttcat gatgcactcc tttttttgtt gctaataata acaaacaatt ttttcttcta
    18121 taacagaata gcttattatt aataaaactg tcaatttttt tattgattaa aaagatattt
    18181 tttgatttta agtattttca attatttttt gttacttaaa ataactttat agattgtgaa
    18241 taactttata cataaaaagt ttacgtgagt ccatacaata taaagaataa aaaatgtgat
    18301 gttttaaact gtaaccaacc ataataaact gcttctcaat tctccctcat acgcaataca
    18361 taggcgtcaa gcaggattct cgcgatgatc tggagaggca agcgtgaacg tacttcataa
    18421 tcagggaaat aagaaccttc tgatttgaaa cctacgagat ttatctcgca ataatctttg
    18481 agtgtagagg aatgattggc tgtaactaga atcgaaccaa tctctgcatc atagcagttc
    18541 tttgcggcgg tgacgagttc ttttgtctcg ccgttcaaag aaacaaaaat aacgctgtct
    18601 ttcttagtta gtttccgact gatgcttttg ataatctctg gatcagtatg catttgacaa
    18661 ttttttcctg ttaattgaag ttttacgagc atctcttgac caatcatttc tgaaaatcct
    18721 cgggcaaaga caaaaacccg gtcagtaaat ttgattcttt gtattgcatc ttcaatgttc
    18781 ccgatttcca acatattgat cgtacgtacc acttcttgtt cattttttag aatggctcga
    18841 cggatacctt tgtctacttt atctaaaaag aaaaattgat gttcttgttt tctccttctt
    18901 ttagatggtg cttaaacgaa gtaaatcctt catagccttt tttcttcatt gtccgcacaa
    18961 tggtggctgt tgagacattt gcttgttcac ttagtttcac gatggagtag ttagggatct
    19021 ctaggatgtg gtgttcgata aagttccaga ggtactgttc tgtttcactt aatttgtgat
    19081 ccatattctt tccttctttc actaaaagtt agttaaaaaa tagcacgatg tgtttataaa
    19141 tgtaaaggtt ttctttgtgt tggaacgatt aagaaaacat tttctctttc gcgtatttca
    19201 taatagattc aaggaggtca ttggttatgt ctatctacac atgcacgatg aatttggcaa
    19261 ttgatctatt tattgaaaca gaggagatgc atccttttat ggtaaaccgt acaaaggagg
    19321 atgacattca ggcaaacgga aaaggagtaa atgtgtcact agtattaaag atgctagatt
    19381 tcccaagtac ggcattaggt ttttctgctg gtttcacagg aaaatatata gaagactatt
    19441 tacagaagaa acaaatccaa acagagttta ttgaagtgcc tggtatgacg cgtatcaatg
    19501 tatttacaca agtcaatcaa acgagagaag aatacaaatt agtgaatcaa ggacctgaaa
    19561 taccgcaggc agctgtccat aattttttaa atcaaataag agcattacaa gcagaggatt
    19621 atctttgtgt ttctgggagt ttaccaagag gaatgtctcc gaaggtttta gtggaaatca
    19681 gtcggatttg tcaggaaaag gagattcatt tgattattga tagcagtgat caagaggtca
    19741 tggattgttt gccctatcga ccatttttgc tgaaaccgaa tgaggaagaa ctttcttctt
    19801 ggttcggacg aaaaatggtt acagatgaag attactttgt ttatggacaa cgactggtag
    19861 agtcaggtgc agaaaatgtt ttgttatccc ttggtgagaa aggagcgatt ctttttacga
    19921 aagacagggt gattcgagga aactcgccaa aaggaaaagt tgtcaataca gcatgtgcag
    19981 gtgatgccat gttaggcact tttttagtag gatacatgaa tcgacgaccg cttgatgaaa
    20041 cgttacgtaa aagcatagca gcaggcagct ctactgcttt tcgtaaagga ctgactgatt
    20101 ttttggatgt ggaggaatta agtaaacaaa tcaaaatcaa ggaagagagg ttcgaaagat
    20161 gggaaaatat caactaattg cagcaaccgg ttgtccgaca ggaattgcac acacctacat
    20221 ggcgcaagag gcattagagc aagcagctag aaaaaaaggc atcacgatca aagtggagac
    20281 ccatggacaa attgggatcg agaatgaatt aacggctgaa gaaatcaaac aggcagatgc
    20341 tgtcattatt gccgcagaca aagatgtcca ttcagaaaga tttgcgggaa aacgagtcat
    20401 tgatgtttct gtcagtacag gaatcaagga tgcacaacgg ctgattgacg aagcattggc
    20461 aggaaaaggg accatcttag cagataatga agctgttgat actttagaat cagaaacgat
    20521 aagtggtgct aattttggtc gcagcatcta taaaaattta atgaatggcg tctctcatat
    20581 gttgcctttc gtggtagctg gcggagtatt gattgctatt tcatttgccg tttggggaat
    20641 ctattctttt gatccagacc atgcacaata caatgctaca gcggcgatgt taaaaacggt
    20701 tggcgatgca gcaatgggga tgatggttcc agttttagca gcttatattg cagaagggat
    20761 cgcgaaacgt ccagggttag tcgttggatt tgttggtgga atcgtggcca tgagtggcgg
    20821 tactggattt ttagtaggta ttttagctgg gttcttagca ggttatttta tcttattttt
    20881 gcaaaagcta ctgacaattt tacctaaaca actagatggc ttgaaggcaa tcttcttata
    20941 tccagttatt ggtgtagtgt ttatcggcat cgtgatgtct ttgctggcgg gtccaatgaa
    21001 ggctataaat gaaggaatga tgagcttttt agctggattt gaacattcga atccacttgt
    21061 tcttggcgtg attgttggtt gcatgtgtgc gtttgatatg ggaggaccga ttaataaggc
    21121 ggcatatgta acaggtacag ctcttttggc acaaggaaac acgactttta tggctggcgt
    21181 gtcagtagct tgcattgcac caccgttgat tactggtttt gcaactttat tgtttggtaa
    21241 atattttgat actaatgatc gtaatgcagg tttggttaat tttattttag gatcaactca
    21301 tattacggag ggagctattc cgtttgctgc gaaagacccg atccgagtat taccaacgat
    21361 gatgttaggc tcatcaattg ctgctgtctt gacctatctg tttggtgtcc aagtaccagc
    21421 cccacatggc ggttttttag tgttacctgt agtgacggga aaaatccaat gggttacagc
    21481 gattcttatt ggttcgatcg ttggtggagt gatactaggt ttgatccaaa agaaaagagt
    21541 aactgataaa gacaagaaga tggataataa agcagcaaat cgtacagtta tcgaagaagg
    21601 aagagcagga ggcttatcat gacaatcatt catgaagaga acattttttt acaacagcca
    21661 ttagatagtc aagaagaagc atttaagttt ttagcaaagc aaacattctg tttaggaatc
    21721 gctcatgacg aaaaagaagt atatcgaaaa cttctagaaa gagaaaaaga aggtactaca
    21781 ggaataatgt caggttttgc tatccctcat gcgaagtctc aaacaatcaa cgaacctagt
    21841 atgattatcg tcacactgaa caaaggaatt gaatggaaca gtttagatag acagtcagtt
    21901 gattttattt ttgcgttatt tattccagat tcagaagcag gaacgactca tttgaaatta
    21961 ttgtctctcg ttgcacgatc attgatgcga aaagaggtta cagaacagtt gagaaaagca
    22021 aaatcaaaaa cagaaatagc cacaatatta actaaagaaa taggtgaaga tctatgaaga
    22081 agatgagtat agaaaagcag gaacgtttga agcgattgac ggatgaagct ggaattatta
    22141 gcgcgttagc aatcgaccag cgtggtgctt tgaagaaaat gatcaaccaa tataaagaag
    22201 ctacatcaga agacatcatc caatttaaac agatggtttc tcaatacctg actccctatg
    22261 cctcagctat tttacttgat ccagaatgcg gcctgcctgc agcagcgctt agagagaaag
    22321 aatgtggctt gctgctagct tatgaaaaaa ccggctatga tacgaaaatg ccgggaagat
    22381 tacctgattt attgaatatt tggtcggtga aaaggttaaa agaagctggt gcggatgctt
    22441 gtaaattttt attgtactat gacgtggatg aaccagcaga gattaatgtg caaaaacaaa
    22501 tagttataga acggattggt tcagaatgcg atgcagaagg catacctttc tttttagaga
    22561 tcctttctta tgatgcaact attggcgatc cgtcctctct tgcctatgca aaagtaaaac
    22621 cccataaagt tattgaagcc atgcgagaat tttcaaaaga acgttatcaa gtggatgtat
    22681 tgaaagtaga agtgccagtg aatatgagat ttgtggaagg atatgggcaa gagacttgtt
    22741 atagtcaagc agaggcatcc gcgtatttct atgaacaatc gaaagtgact gaacaaccgt
    22801 ttattttttt aagtgcggga gtcaatgcta cgttatttca agatacatta cgttttgcaa
    22861 aacaatcagg ttcgacattc aatggtgtct tatgtgggcg agcaacatgg gcgaagggag
    22921 tggcaccttt tgttaccgaa ggcgaagaaa aagcgagtag ttggatgtta gaagaaggaa
    22981 aacaaaatat taaggaatta agtacactat taaaagaaac agcaacacct gtctacgttg
    23041 atagataaga aaaagttgtt tcttcataaa aagatgctgc tgcaattaga tagcgatcaa
    23101 tcgatgattc aaattataca ttcacttaaa taaaaatatc gactagattt ctttttcaaa
    23161 aatcttggtc gatattttta attgctaaaa ctgttaatga atttttatta cactcttatt
    23221 tactatctac ttccgcttct gctgctttcc tgcgttgcgg cctttgttat ttgtactgtt
    23281 ttttggttgt ttgatttgtt ttgttgcttg tttgttgtca gctggttttg ctgattctgt
    23341 cacgtctttt cttggagtga cgacttgttt tggcgggttt tgtttcaact cttctgccac
    23401 ttgtgctttc aagcgtggtt tcatcataac gtttgtgatg aatgtttgca gacagctgaa
    23461 cacaccaccg actacccagt aaagtgtaac gccggctggc gcactgatcg acatgaagac
    23521 gatcatagca ggagagacga tcagcatcgt acgcatcgtc tttttctgtt cttcaggaat
    23581 accgattgtt gaaatatatc cttgaagcag ataagcgacc cctgcaatgg ccacaagcac
    23641 catacttggt gagcctagat cgatgccgta aaaagatgat tcacggatac cttctgtgta
    23701 gcgagccgta aaatacaagg cagagaagat cggcatttgg atcaatagag gcagacagcc
    23761 gattccgccg gtcatactca atccgttttc gcgatatact tgctgcattt ctgcttgtgc
    23821 tgccatttgt tcttcacgtg ttgttgcagc ttttagcttt tgttgtgctg cttcaacttg
    23881 tggttttaac gcttgcattt tttcagattg gatcattgtt tttttcgatt gactgatacc
    23941 tagtggcaag atgatgatac gaacgatcac agtcattgca ataactgccc agccgtaaga
    24001 ccaattgaaa ttctcaacta gatatgtaat cgcttggccc ataggatgga cgagtactcg
    24061 ataaacgatt cctgaagtgt cagggtttcc gtttgaatcc atccgcacac agccagataa
    24121 aaagagcagg atactgacaa gtccggatcc caataaccag tttttccatt tattcataga
    24181 atacttcctc ttctataatt tttacacaaa cttaactata ctaaaaaagc gcatggaatt
    24241 caatcaactt catagaaatt tcatataaat attctttctt tttcgtagcg aaaaattttg
    24301 aaaaaagaca aaaaatcaag aaagaaatac ttggaaagaa aagagtgatt ccaagtgttt
    24361 ctttcttata taaaaaacta aaaacttttt tgttctgtct ggaaaatatg ggttaagcaa
    24421 atttattgca agttatagat cagctttttt actacctatc tttaatactt gaggcaaagc
    24481 gcctcaaaaa caacctgatc gacggtgttc aaaagtcagt ttctcggtat taagtcaaat
    24541 ttatgcaaaa atgtggaaag ccattttcac aaaattttcc ttaatactca aaactaagcg
    24601 accttttcac aaccttatcc caccacatca aatttctttc gttcctcaat catcggatct
    24661 tcttggacat ccacatactg cactcgtcca cttgggctcg gagacttctt gacttcttcg
    24721 ataaattttt ggatgatgtc gtcatttccg attgcttcga ttgtgactga gccgtcgtct
    24781 tcgtttttta ccgttccggt cacgcctaac tgatcagcaa ccatcttggt catatagcga
    24841 aatcccacgc cctggacacg tccttggaca ttcattttaa ctttgcgcat gttcgtcacc
    24901 tttctttcct gttttataaa tcaatgatac cgattttttt aggatgaaac aagctcaagc
    24961 acctattcca tgatataatc aggtgaggtg aaggaatgtg aaagagatcc aatcagcaaa
    25021 aaatccaaaa atcaaagaat taaaaaagct acataaaaag aaatacagag aagaaaaggc
    25081 agaatatctt ttggaagggt tccatctgat cgaagaagct gcgtcgtctg atgcagaaat
    25141 aaaagaactt tttgtgacac agagaggtat gaaagaatgg ggagactggc tggctgtaaa
    25201 caaagagatt tctacttttc tagtttcaga tgaggtcatg accgctatgt cagatctacc
    25261 tacaccgcaa gggatcttag cggtgatgac gttaacatct gaagatacgc cagatttttc
    25321 aggaggctgg cttttactag ataatgtaca ggatcctgga aatgtgggaa cgatgatccg
    25381 tacggcagat gcgtttggta tggctggtgt tttattaggt aaaggaacgg cagatattta
    25441 tagtacaaag gtgctgcgaa gcatgcaggg aagcaattat catttgcctg tgttacaaaa
    25501 agatttggca gaagtgatcc ctgtaatgaa aggcaaaggg tttacggtgt acggtacaga
    25561 attaaatgaa gaagcacatg cattagacaa agtagaaaaa acagaggatt tcgctataat
    25621 catgggaaac gaaggtcagg gagtaagtca ggaaatcttg tctttgactg atcagaacgt
    25681 atatatccca atgaaaggaa atgcggaatc attgaatgtc ggagtcgcag cagggatcgt
    25741 tctttatcat ttttctttat gattaaggaa ctattaagct ttagctattt tatctagagc
    25801 gactagaata atccgaacac tggtggtata cttagatcaa tttcagaaga aaatgaaatt
    25861 caaaaaggtg gcagatcgat aattatgaca gaaaaatggc gtgaagacga agaatatatg
    25921 tcttatgtac aagatctttt agaaacagaa gcagtgaaaa aattagcgaa ttacacacag
    25981 catgttcatt ccactcgttt ggagcattcc atcagtgttt cttactatag ttatctgctc
    26041 gcaaaaaaat ggggtggcaa tgctaaagca acagcgcgtg ctggactttt gcatgatctg
    26101 ttctactatg attggcgtac gacgaaattt gacgagggga cacatgcgta tatccatcca
    26161 agaattgctg taaagaatgc agaaaaaatc accgatttgt cggatcttga gcgagatatc
    26221 attttgaagc acatgtgggg tgcaacgatc gcaccgccta agtataaaga aggatatatt
    26281 gtgacattcg tggacaaata ctgcgcagtc aaagaagcgg ctcagcccat gtctgcaagt
    26341 atgcgtaaga gatggcaacg ttactttggg aaagaatcct cgatttaaca ggtaaaacca
    26401 ataatagacc atattgaggt tgtgacagaa gtggtcagct tcaagaaata agaaggaatt
    26461 tacgaaaatt acttctcaaa tttttgtgaa gtttcggctt attaccgcag atgcaagctt
    26521 ttgaacacca ttcattcgaa acaagggact ttgacacgac ttttgtcaca gtcctttttt
    26581 ctgtttgcag ttgactatct gttcaagata cggtttactt ttatttatcg aatgaatcat
    26641 gtacatagaa gaataagcat taaagggggt gatgataaga tgcaaaacgt atcttattta
    26701 aaagagtccg ggatcttcag gtaacacata ctttgcagaa gatcactttt ttctacaaag
    26761 tatgcacttt ggttagaaga aaggacttta aaatcatgga acaaacaata aaaccatacc
    26821 aatatttttt tataaaaaga gaagtagaac agttattaaa tgcgtactca tctgtcaatg
    26881 atccaaaaac ggtacaaaca gttcaggcac tagcaactga aaagattcga gacatattag
    26941 aacacgaact gccagaaatc gatacatttt taacgacagt tttagacgta aaactgacaa
    27001 aagcgcaagc agaacgagca ttggaggagc tgaagcaaat cgttcagccg tttatgcagc
    27061 ctagcaaacc acaaatcgag aaattattcc gaaaagtgaa aaaactcaaa caaccagctt
    27121 ggaatgaaat cgacttgcaa gaacatacgt acatcggctg gaatgatcca ggtacgcaga
    27181 aaaaattcat gatctattac gaagatgaaa aattaaaagg gattagtggt actttatcac
    27241 caacgataaa taagggaatc tgtgcaatct gtcagaaaac atcgaatgtt tcgctttttc
    27301 tttctacaac gaaagcaggt tctgatggca cgtatacgaa aaaggggaat tatatttgtc
    27361 atgatagtga ccaatgtaat caacagttaa cgaaattggc tcctttctat gaatttgctg
    27421 aacgtgtaaa gaaagaacga taattttatt gttttttaca gaaaaatatg ctatctttta
    27481 atggaagtga ataggtgatg gtgttcgcct ttaaatgcta acgaaagata gctaatgacg
    27541 cctactaaag tctggggaca gcccctttct ttagtaggcg tttttttatt gaggaggaat
    27601 tttttatgga aaaacaatta ccgagtccag tacgcatttt agtgtacatg ctgaagtggc
    27661 tggtgatcac agcgattctc ggtatattca tggggagctt gtctgctttt ttcttaaata
    27721 gcctgacagt tgtgacagat atccgactat cacatccttg gctcctttat ctactaccag
    27781 ttagtggtgc gctttttgct tatctctatg cgtatcacgg cggtctttct agtcgtggaa
    27841 acaacttagt gatcgatcaa ggaaatggtg gagaagaaaa aatcccgttg cgacttattc
    27901 cacttacact gtttggaacc ataactaccc atttatttgg gggatctgtt ggccgtgaag
    27961 gaacagcagt ccaaatgggg ggagcgttag cagataatac agcacgtttg ttccgattgg
    28021 ataaatcaga acgggaaatc ttgattatca gtggaatcag tgcgggtttt agttctgtat
    28081 ttggcacacc tttagctgga acattatttg gattagaagt gttggcaatc gggaaagtcc
    28141 gaacagaagc gatcttccct agcttctttg ctgcactgtt tgcaaatttc atgacagaaa
    28201 gctatggtgt ttctcatcta cattaccaaa tgggtgtgat tcctgaatgg agtatgttgc
    28261 tgttcttcaa agtttttgtt gctgggattg cttttggttt gattggttgg gtattcagcc
    28321 gttcgatcgt ctttttaaaa gcgcgatatg cacaatggat tcctcatcct gtttggcgaa
    28381 atacgatagg tggagctgta gttgtggcag cagcattgat tttgcaaaca caacgttatc
    28441 tcggattgag tcttccgtta cttcaagaat catttaatgg acaggcacat gtctatgatt
    28501 ttattgggaa gttattcttc acagttttgt ctttaggcgc gggatatcaa gggggagaag
    28561 tgacaccatt gtttgaaatt ggtgcaacgc ttggtgcagc actagcgcct ttgctccatg
    28621 tttctgttcc ttttcttgca ggattgggct ttatcggagt attttctggt gcgacaaata
    28681 caccgattgc ctgctttgtg atggggatcg aattgttcgg ttcacaagcg gcagtatact
    28741 tctttatgat ctgcttgatc agctttatgt gttcaggcaa cagcggtatt tattctgctc
    28801 agcaagtagc ggtcaaaaaa gggatactct ttttgccaat agttaagaga atgaaagaaa
    28861 aaaacaaggt gtgacatatg ttttgtcaca ccttgttttt ttagaaaagt aaagtaatca
    28921 gcgataagaa tgcggagcct gcgaaaagca atccgcaaat gatcatatgt ctttttttgt
    28981 tcatcatcaa gatggcgatg tattctctta aaaacgcatt aggcaagtag tagaaagctg
    29041 tttttgcacc aataccattt gctttcaatt tggcttgcca cgcataaaga ccggctctaa
    29101 aaatgtggta attgttggaa ctaaagatcg cgcggtatgg ccctttcatt tgctgatcca
    29161 tgatttcctt tgaatagagc atgttctcca aagtggttgt cgaattggtt tcgacaagaa
    29221 tgtctctttc agggattcct tgttccatgg catattgttt catcgcaatg gcctctggta
    29281 ctttttcgtc tgctccttgc ccgccagaca tcaataagat gggcggattt aatgtagcac
    29341 ggctttgagc ccgataaaaa gcaattgcct tattgattcg cttggctaga agaggagaaa
    29401 ctgtttctcc attgatcaac ccagcgccta acacaacgat gaagtcttga ttgtatcgag
    29461 gccggttgaa ctgatacaag aatgagacag tcaaaaagtt gtagaatacg ataaatagat
    29521 agatcaagat caggggaacg cagaaaaaca aagcatttat ccattgcggc aaatatttta
    29581 acaagaaaaa gtcaaaaaca agaaacagtg taagaaaaat ggctagtatc aacgttaaaa
    29641 gattagctaa tgaatgcgat tctctacgta aaactgtgac cccgttccaa aaaagaaaaa
    29701 caatcaatcc ataaatacca aataaaagga caagtagcaa tggaatcgtg atcaaggcga
    29761 tcagtccgcc aaggaaaata ttttgcgttt catacagcaa gacaaacaag tagatgccga
    29821 aactgatgag gaaaacattg aataaaagac cattcagcag ccttcgtttt tctgtgaaat
    29881 aagaaaaagc aaagatacta aagaacaaca atggaatcaa aaaataaaag gtcgaataaa
    29941 aaatttccaa cacgacaaaa taagttaaga ttaccgtaaa tgtccacgta ctgccgtaaa
    30001 agaacaagga aggatccttc ttctgttttc gccaataaac gatagagaat accccaataa
    30061 gatagagaac taaaaagatc agatctctgg ttagattcat aaattcaact cctttttctt
    30121 atacagtata acgaaaatag atgaaaaaag ctgttattta aactagaaaa agcaaaaaaa
    30181 catctttccg atggaaagat gtttttctta ttgttcaatt aaaacaagtt gccgaaaaat
    30241 tctgcgacgc gtcgccagcc aatcacgaat atattcgctt tttccactgt tttatccgta
    30301 atgatctctg ttgaaggtgc attgttgtct tctaaatagc ctaatttatc gtctgccaag
    30361 gtgatcgtag cggtaccgat ttttgtacct ttatccatag gtgcttggat ctcattgtca
    30421 gtgacttgct tcttgtcaag tgttggcgtg atcgttaatt tgccagtatc catatcgttt
    30481 cgtacccata cttttacagg gcttttaagc acaacaggaa ctgttgattc ttttccgtct
    30541 tttacatcaa tggtttttag actaggaata cttgcgttag cttttcctag ctctttttct
    30601 gaccaattgt catagcagta gtccatcaaa cggtctgttt cattgaagcg ggcactcggg
    30661 ttttccgcat ggccgtccgc attcaatacg acagtgatga tccgttgatc gtttttagtg
    30721 atcgtaccaa cgaaacaagc acctgcaagc tcagtcgtac cagtttttaa tccgtccacg
    30781 ccttccttgt aattaacgaa tcctgggagc atccagttcc agttgaccat ttccactggt
    30841 gattgcgtat tttcgccaaa catttgggtc gtagtacttg atacatccag tatttctggg
    30901 aaatccaaga tcaaatggcg ggcaacgatg gccacatctt gagcagacat ttgattttcg
    30961 tcgttttctc cagtgccttc tggtcggttt tcgccaagat aagagttgtt caatcctgat
    31021 gcattaacga ttgttgcatc tttgattccc caatctttca attgttcttt cattcgttca
    31081 gtgaatttag cttcgctgcc agagattttt tctgccaagg ccaccattga agcattggct
    31141 gactggatga ttgcagagtc gaataattct ttgacagtgt aggtgttttc tttatgcaaa
    31201 ggaacattcg ataaatctgg ggtgatactc aaattttctg cataatctga aatcgaaact
    31261 ttatcatccc atgacagttt tccttctttt acttgatcaa ggacgatgta aagaccgatg
    31321 atttttgtga ttgaagcgat ccccatggtt ttttctccat cttgatcata aagaatctta
    31381 ccgctttgcg catctacagc aaaagctgct tttgcattta ctttgaacgt atcttcagct
    31441 tgcacagcaa cagctggtag aaaagaagca aggcaaagaa tgagactagc caataatagg
    31501 actagacgtg ttttttttat ggacatatcc gatctccttg taattaattt gtttcgctac
    31561 aaattaaaat tttatcagag aggggagaga gtttcaatgt ttctgaaaaa actttaggat
    31621 aagaacgcgc gttatggaag tttagcggtc gtttttacgt acttttacag gaataggctg
    31681 tgtttccgca tctaataagc gggaagcgct gaaagcaaat aaactgataa tacttaataa
    31741 actgaaaatc ataatcaaat gcataagatc cacctctttt attctttttc ttagtttatc
    31801 agcatttcat gaagaatagt tgaagactgg ggctaaataa ttgaggaaat tatgaagata
    31861 acttaaaaaa atagctaaat ttaaaaccgt agaaaccgtt ttattttttt agatacgttt
    31921 tattgtatgg aaaaatagtg ttgtggtaga ctttagatag aaacaaagga atgatttttt
    31981 taggaggggt acgtttatgg caaaaaagga taaagaatta ttgacacaat tgacttcaga
    32041 aggcgctaaa ggaccattcg tcacgatcat gctgaatacg catgtcgccc atcaagatgt
    32101 ggaaaaagat cagatcaaat tcaaaaattt tgcgaaagaa gcaaagaaac gttttgagaa
    32161 aaaatattcc gaacatgact ggtccccgtt ccaagaaaaa attgaaaatt tgttaggaga
    32221 tccttcgttt tggcgtagtg caactacgag tgtagcggtc attataactg ctgaccagac
    32281 ctatatccat cgtttgagta tcccggtaga cgatcaatac tatgtaagtg atcttcctta
    32341 tttactggct attatcaaaa atgggcagtt caactattct tattatttat tgggattgaa
    32401 ccgcgactcc atgaaattgt atgaggtcag caacaaacaa gtaaaagaag tatctctacc
    32461 agaaggggca ccggttgatg tcgttactgc attgggatct gaactgacag gtggcggttt
    32521 gaacttctct tctaatggag gaggcggagc ccgagatgga gtaactttcc atggcgtaaa
    32581 tccaaaagat gaagaagtag agatcgattg ggtcaactat taccaagctg ttgatacgta
    32641 cttgaaggat tctttcgaaa atcctgaaca atggccgatt tatttatttg cattaccaga
    32701 aaatcagacg atgttcaaaa aaattgctaa aaatccctat tattgtgcag acgttgcgat
    32761 ttctgcttct cctgcgcagc tatcctttag agatatcgaa gaaggggcga agaagctgtc
    32821 aagtgaactc gcagctcaag aatcaaaaga atacaataaa ctcttagata agaaattcat
    32881 cgatcagtta gttgatatcg ttccagctgc gaaagaagga aaagtgtcac atttatttat
    32941 cgctacgtca aacttagctg atggtttcgg tgaagatcct gaaacagaat atgatcggcg
    33001 tcaagtgttg aatgcattag cagatgatgt gatcattaat ggcgggaaag tgtttatttt
    33061 ggatcaaaaa gatgcgccag atgaaaagag tctgacagcg attcttcgtt attaaaagag
    33121 gttgtgaaat cagtgttttg acctgagtat tagagaaaca aacggaaaaa tagtttcaca
    33181 tatttttccg ttttttgagc taataccgca gatgcaagct tttgaacacc gtttaaggaa
    33241 gaggttgtga cagaagtggt cagcttcaag aaataagaag agattgacaa aaattatttc
    33301 tcaaattttt gtgaaatttc gacttatttc cgaagaagct acttctggaa caccgtttaa
    33361 aaaagaggtt gtgacgtggt cacgacctct ttttgacgat tatgatacaa aaaacatcat
    33421 ttatgaacaa aatgtgaata acgggcgttc ttgagatatg attttaattg ggaaaaactt
    33481 atcgataagg aggtctttat gaaaaaaaga ctgttatggt gtttgctgtt tctatcccta
    33541 agtttaacaa gtcagccagt ttttgctgaa gaaacacagc ggtctcctat tacaggcaca
    33601 cgtctgtaca aaaatgttta tgtacagaca acagatcttg attctgcgat tcctgaaaca
    33661 gaagaacggt ctttgcagcc aagatttggt tacttttggt actgtccgac ctgtgattat
    33721 gaaagttgct ggcatttctt acattctaca gctgcagctt ttgcttttac tcatactcag
    33781 aaatatgatg gacatcatcc tgttatttat gaggtataga tatgagcaaa aaagaaaaac
    33841 taatctcgtt gatcgtattg gtttgccttg ttcttctggt aactgtcata ggctatcaga
    33901 aataccatga gaacatcaga cctactaaag aatcttcccc agcctcgacc gttgaaacag
    33961 aaccgataag tagtcagaaa gaataatttt tttagtttaa agaagaacat cagagcaaaa
    34021 aaacaccaac tgaacaatat gtcgtttatt ttaaaaaaag ttcggttttt cactttatgt
    34081 aatcgctgag aaaacttttt ttaataaaaa aagtcgaaaa actctagctt ttttgtaaac
    34141 ggtatgatat actataggag tagtttttgt tcggtaatct gtggtagctt gtttcaaata
    34201 aacatcttcc agatatacac cattcaagta attgcaaaat atgtgttgat acacaaggag
    34261 gatttttatt atggaaacag gtacagtaaa atggtttaac tcagaaaaag gatttggatt
    34321 catcactgca gaaaacggaa acgatgtatt cgttcatttc tcagctatcc aaggcgacgg
    34381 attcaaaact ttagaagaag gccaagcagt aactttcgat gttgaagaag gccaacgcgg
    34441 acctcaagca acaaacgtta ctaaagctta attaacctat actaaaaaat aaacgcccag
    34501 acatttgcgt gtctgggcgt ttttgtctat tttctttaaa aagcgatgag agtatttttc
    34561 tgcactttgt agtataattt caaaagaaca ttagaggcag gagaagagga agatattttg
    34621 aaaccaagaa cttatgcagt cgttgatatc gaaacgactg ggacgaatcc aaaagaagat
    34681 cggatcatcc aatttggctg cgtcatgatt gaatcaggtc ggatcacttc acgtttttcg
    34741 atcgatattc atccagggcg gaagatttca aaacaaatcc agcatttaac agggatcacg
    34801 aatcaacgcg tccaaaaagc gccttatttc gaagatgtcg cccaaacgat ttacaatctt
    34861 ttggcagaca ccatatttgt cgcgcataat atttattttg attataattt tttgaaccat
    34921 gaactcatgc gatgcggact tcctagtttg aagataccag gcatcgatac agtagaactt
    34981 gcacaaattt tcttgccgac ggaaccaagc tttcgcttag ctgatttgtc agaaagcctt
    35041 ggatttattc atgagaatcc tcatcaggca gatagtgatg ccgaagtgac gggtcaactt
    35101 cttttgctga tcgaagaacg gatgagaaaa ttgccaatca tcacgttaga gcagattgcg
    35161 cgattaagta gacacacagg tatggatacg agtcgtttca tttatcatgt gattgaagaa
    35221 atgaaagaaa aaccagagcc acttgatccc tcattagaaa tcgtcgatgg gctagctttg
    35281 cagaaaaaag aagtggaact attcatatac gtccattatg gcgagcggac atatccaaga
    35341 aaaaaacaag caaaagaaaa aatgtttggt aaaacactga tgtatcgaaa agaacagaac
    35401 agactgatga atgcggtcta cgaccatttc acaaaagatg aatcaaaaga tttgatgatc
    35461 gaagcagcta caggaatggg taaaacaatc ggttatctgc tgccattgag ttatttggct
    35521 acacctgaaa aacccgctgt catcagtacc gtttcgctag ttttgcagca gcagatcata
    35581 gaaaaagaca ttccattgct gaatcaattg ctagatcagc ccatacaacc tgtaattatc
    35641 aaaagctatc gccactatat tgatttacag cgttttaaag gcacacttgt ggaaccgcca
    35701 gaacaaaaac aatatgcttt gtatcaaatg gcggtcttag tttggctgac gcaaacgaag
    35761 accggtgatt tggatgaatt acatttaaca aatttgaacc attcattctt tgcagatatc
    35821 gcgcacagag gcactggatt tttagcaaga aatcagtcat tttacgaaca agactttgtt
    35881 cgtttcttgc aaaagaaaat caggcaaagt aattttttga ttgtcaatca tgcgttttta
    35941 atacaagaaa cacagcgaaa agaaccattg cttccagcta gtccattttt gttgatcgat
    36001 gaagtacatc atttgccgga aatcgctgaa aaagtaaatg acaaacgatt aagtattaac
    36061 tatttccata aacaaatcca gcaattagaa gaaccaaatc agctgtttga ccgaatacaa
    36121 agctatttac cgaaagaaca tgaagcctta cgctggttat cgatttatcg agaagaactt
    36181 tctgcgctat gcgaagcaca gatttgtatg gcagaaggat taatgagttt agtgagcggc
    36241 aagcaaccta acggacagta tccagaagaa gtcatgacga caaaagagat gttggatcag
    36301 ctgccactgg aatctgggac agccattgat cacctgcagc ttttttatca ggagatccag
    36361 cagctacagt cacaaatgcg tctgactttt gagattatcc aagaaagctg gacaaaccag
    36421 atgcggatcg atttagcaag tttatatagc ttatttgatc aattagacaa gcagtacttg
    36481 ctgatggatc aatggctgga agactggcga gatcatttga tccattggtt cgttcctggg
    36541 aacacagcgc agcagatgat ttttcatctc catgattttc aagcggctat gttgccgtcg
    36601 actgtttggt atcctcgata tgatcgtatt ctttatattg gaggaacgct gaagatcggc
    36661 cctaatcgac actatctctc taagcggctt ggcattgaag cagcacctct taaagtgatt
    36721 gcctctcctt atgattatga gaaacaggca aggatctatg tgccaaaaga ggcacctgcc
    36781 gtccatcaag tcagcaatca agcatatatc gattatttag agacagcact tacaggtctg
    36841 atcgaacaag aagatcggcc aatacttgtg ttattcactt ctcatgatgt tttgcagaag
    36901 gtctatcaga aaatgcatct gtctatgcta gaaaaaggac gagaaatact agctcaaggg
    36961 tttggcggaa gccgggagaa gcttttgaaa cgcttcattt tgtcagaaaa aagcgtattg
    37021 tttggcgctg acagtttttg ggaaggtgta gatttgcctg gagatgcttt gcagatcgtt
    37081 gtagtcacac gtttaccctt cgataatccg cttcgcccga tggtcaaagc taggaacgct
    37141 tatttagaat cagaggggat caatcctttt taccaggaat ccgtacctaa agcagctttg
    37201 aagttacgcc aagcattagg acgcttgata aggacggaga cagatcgtgg cgtattgctt
    37261 attttggatc gaagactagt tactgcaaaa tatggtgcac ggatcatcca tgcattaccg
    37321 aaaaaagtac cgatcaaaga gctagctatg gaggaaatct atcaggatat ccatgaattc
    37381 ttaaagaaaa atgaagaagg aagttagagg agctgtcttt tttcataatt aaaatctgct
    37441 ataatgaaaa ggaatgaaga taaaggagcg acgacccttg aagaaaaaac agacaaagga
    37501 aaaaacgatt aatcgcgtgt tacttggctt gatcgtattt ttattagcgg tcatcgtgat
    37561 cagctcgatt ttttacttgc gttccagtcg tccggcggtg caggcgaaga aagaagcagt
    37621 agaaatcgca aagaaatatg caaatcttga ggaagccgat catttttatt ggtttactcg
    37681 aaagaagaca tacttttcac tgacaggtac aaatgataaa ggaaaagaaa tcgccgttat
    37741 cattcctaaa tctggtgaaa aagtaaaagt attggatcaa acaaagggac tgactgaaaa
    37801 tgaagcaaaa cagacaattg ctgcggccca tcctgaaatc caaatcgaaa aagctgcttt
    37861 agggatgtat gatgatcagc ctgtgtggga agtagtagga aaagaaacaa atgggaaact
    37921 gaattattac ctgattggct ttgaatctgg agatgaagtc aagacaatca agggaattta
    37981 aaaggtaaag gaatgaatgg gatggagtta tcaaaaagaa caaaacgatt agaaccgtct
    38041 gtcactttgg cagctgcggc aaaggccaag gcattaaaag ccaaaggcag agatgtgctg
    38101 agtttgactg tgggagaacc ggattttgcg acaccagaaa acatccaaga agcagcaatc
    38161 gaagcaatcc gcaatgggaa agctagctat tatacaccaa cagcaggaat cccagagctt
    38221 cgacaggcaa tcgttgatta tctgaagaaa aactatggac ttgtctatga accttcacaa
    38281 acagtcgtaa cagacggagc gaaatttgct ttgtataccc ttttccaaac gatccttgac
    38341 ccgcaagatg aagtcatcat tcctgtgcct tactgggtca gttacggtga gcaagtaaaa
    38401 ctggcagaag gacttcctgt ctttttgaaa ggagaagaat ccaatagctg gaaagttact
    38461 gttgagcagc tagaacaagc acgttcagaa aaaacaaaag ccgtaatcat caattctcca
    38521 tcgaatccga ctggaatgat ttatagcaag aatgaactgc aggcaatcgg tgaatgggca
    38581 gtaaaaaatg atattttgat agttgctgat gatatttatg gccgtttagt ttataatggc
    38641 aatgagttta ctccaattgc aacgatttca gaagcaatca aaaatcagac catcatcatc
    38701 aacggcgtgt ctaaaacata tgcgatgaca ggctggcgca ttggttatgc ggtgggaaat
    38761 cctgtgatca tcaatggaat gatcgctgtt gcttcccaat caactagcaa tccgacagca
    38821 gtcagtcaat atgcagctgt tgaagcattg aaaggcgagc aagatacagt ggaagaaatg
    38881 cggaacgcct ttgaagaacg cctgaatacg ttatatccgc ttgtggcaga actgccgggt
    38941 gtttctcttg aaaagccaca aggagctttt tatctttttc ctaatgtaaa agaaacgcta
    39001 cgcatgtgta aatatgaaaa tgtcacacaa tgggtagaag atcttttaga agaaacaggg
    39061 gtagcgcttg tgactggcga aggctttggg gcaccagaaa atgtccgcat gagttatgcc
    39121 actgatcgcg ctacgttaga agaagcggta cgcagaatca agcaatttat tgagagtaaa
    39181 agtcaaaatt aatcctgaag aaattcaagg aatataaaag gagagtcata cgtggaacaa
    39241 attcaaatca tcgattcgaa aaaccatgtg ggagaaacag taacaatcgg cgcttgggtc
    39301 gcaaataagc gatcaagcgg aaaaatcgca tttttacaat taagagacgg aacagccttt
    39361 ttccaaggtg tagttgtaaa aagcgaagtg ccggaagaag ttttccaaac agctaaaaat
    39421 ctgcaccaag aaacatccgt gttagtaact ggagaaatcc gtgaagacag ccgttcaaaa
    39481 tttggttatg aaatcggaat tacaaatgtg gaagtggtaa gcgagagcca cgattatccg
    39541 atcacaccaa aagaacacgg aacagacttc ttgatggatc atcgtcattt atggctacgt
    39601 tcttcaagac aacatgcgat tatgcagatc agaaatgaaa tcattcgtgc aacgtatgaa
    39661 ttctttaatc aacatcattt tgtcaaaatc gatccgccga tcttgactgg ttccgcacca
    39721 gaaggcacta cggatctatt cgaaacaaat tactttgatc aaaaagctta tttatctcaa
    39781 agtggccaat tatacatgga agctgctgct atggctttcg gaaaagtctt ttcattcggt
    39841 ccgactttcc gtgctgaaaa atcaaaaaca cgacgtcatt tgattgaatt ctggatgatc
    39901 gaaccagaaa tggctttcac tcatcaagaa gaaagtttag aagtacagga acaatatgta
    39961 gcattcttag tacaaaatgt tttagatcat tgcgaatacg cattagatgt actaggacga
    40021 gacaaagaag tcttaaaaac ttatacaaaa ttgccattcc ctcgtattac ttatgatgat
    40081 gcgatcgaat tactgaagaa aaatggattt gatgacatcg aatggggcga agactttggt
    40141 tcacctcatg aaacgttcat tgcgaattca ttcgaacagc ctgtctttat cctaaactat
    40201 ccaaaagcta tcaagccatt ctacatgaaa ccacatccaa caagagaaga cgtggtaatt
    40261 tgtgcagata tgatcgcacc agaaggttac ggtgaaatta ttggcggaag cgaacgggca
    40321 acggactatg atttcttgct agaacaaatc cgtaatcacg gtttggatga aaaagaatat
    40381 tcatggtatc ttgatctacg taaatacggt tctgttccgc actctggttt tggtctaggc
    40441 cttgaacgaa cagtcacttg gattgctggt atcgaccatg tgcgtgaagc tattccattc
    40501 ccacgtttgt tgaaccgaat ttatccataa gaggtgatga aaaagctgtt ctgcatcaag
    40561 taattagaac agccaagcaa aaacagctgt tcatgttttt gaattggcgg gacttattac
    40621 cgcagatgta agcttttgaa taccgtttag tggagaggtt gtgaaaaagc tgtttagttt
    40681 cgagtattaa gaaaaatttt gtggaaatgg ctttccacat ttttgcataa atttggctta
    40741 ataccgagaa actggctttt gaacaccgtt taaggaagag gttgtgaaat cagtgccttg
    40801 acctgagtat tagagaaaca aaacggaaaa atagcttctc atattttacc gtttttttag
    40861 ctaatatcga gggtcagctg attgaacacc gtttatatca agaggttgtg cgcctgccgt
    40921 tcagctccga gtcacaagga gtaatttcaa aaaacagttt ttcatgtttg atgactattg
    40981 tgacttgtga ccgaggagtt ggccggagag caccgtttat tctaaaaaag aactgcgaac
    41041 tctcgcagtt ctttttttaa aatacgggat aaaggaagtt tccagcagac aagagaagaa
    41101 agcaaaagaa attgctattt gattcacaag gttctataac gaaatcgcaa tcaatcaaac
    41161 atttacaaag aaggtaattc aaatggaaat ctgatttgat gatgcttctg ctgttgaaat
    41221 aaagcagcat ctagcacctg aaaacaaact aatagtaaca ttcgaagatg gagtaggtcc
    41281 gtattttcag catgcaataa tccatatgta agttcaattc acccttgaaa tcatcggacc
    41341 agataaagtt atgaccaatc tatcccaagc aatctagaag agatattagt aaagggacat
    41401 ttactagaag tcttagatga gcctataaat atatgttctg atggcgtcat cagtggtctg
    41461 attgacggaa gcttaggtgt gatcgatctc tctggaccaa acaacgaagg aatcaagggg
    41521 aatccggcac gttaagaaaa aaatagcata aaaaactaga cacttgatga gcgttcattc
    41581 aattgtttga agggactagg ctggtgtcat tttttataca tatattttct ctttcgtctt
    41641 gatagggctt atgggataat ataaggaaga aaatcatcgt tttattcaaa aaggagtttt
    41701 tgacaaatga aaaaacgtat attatttatc ggtgatagca ttacagacgc aggaagagac
    41761 cgagcagaag caactgatct aggtaaaggt tatccacttt tgattgccgg aaaactaatc
    41821 tcccaatatc caacgatgga atttgaatgc atgaaccgtg ggataggagg agacaaaatt
    41881 gcagatctgc aagtacgctg gcaagaagat tgtttagctt tacaacctga ctatgtatcg
    41941 attttgatcg gaatcaatga tacctggcat aatactagcg atcaggctat attcggaact
    42001 gagaaatctg ctcagcaatt tgaatccgtt tatcgaaaat tactaaatga acttcaaaca
    42061 gtgggaatct gcaacatcat cttgatggag ccgtttgtac ttcctataac cgacgaccgt
    42121 catggctggc gtaaagactt agaccctaaa atccaaattg ttcgtaaact tgctaaggaa
    42181 tatggcgcat tgctggttcc tttagatggt atattcaatg ctttagggat tgtttatggt
    42241 ttttcgaaat atacaagaga agatggggtc cacccaacga ttggcggaca tgagatcatt
    42301 gcacaaagct ggatagatgc aattgccgca gtcgattttt ttagtggaga taaaaatgag
    42361 cgaaagaaaa gtgagaaatg atggaaatac ggtgggcagt aaaagaagat ctacctcaaa
    42421 tcaatcagct gattactgat catccagaat cattcgtaaa agcaaaaacg gcagctgacc
    42481 taaatgataa gaataaacta ttgctcgttg ctgtaacaaa agaaaaacgg attatcggat
    42541 ttgcgcaagc ggacgtgcaa cagtcagaag aacgattgga tcagcgacca tcaggaaaac
    42601 taatccaaca cacattagta acaaaagaaa atacggaaga aatccaaaaa aaatttgcag
    42661 aatatttgat actggaagct aaaaaaagaa gaataaaatc attttttgcc cagttttaat
    42721 caaaaacagt aatagaagga gaaatacaat gagttgttta ggaaatgtca tctggtttat
    42781 attcggcgga ctaatcggtg gtcttagctg gttagcagcg gggatacttt ggtgtatcac
    42841 gatcataggt atcccaatcg gtatgcaatg ttttaagatc gcctcccttt cttttgcgcc
    42901 ttttggcaaa gaagtaattt atcaccagtc tggcatgtca ttgattgtta atatcatctg
    42961 gctgatcgtt tcaggcctac caattgctct cgcacatgtc gtcagcggca tccttctatg
    43021 tatcacgatc atagggatac cttttgccaa gcaatctttc aaacttgctc gattggcgtt
    43081 gatgccattc ggtgcagaaa ttgtataaaa gagaataata aaggttagat aaagcataga
    43141 gtcaggtggg atacatgtat ttcacctgac tctatgcgtt ctcctgtata agttcttcca
    43201 tgtgactttt acgtctttta tttatatggg gttactgttt atggaaagtt gaaataattt
    43261 tcattaaaga actctttcta tatttttgaa agcgtagtgg agcttcgaat atctgggaag
    43321 gacattttgc agggattgaa aaaagatatt gtcctatcga aaaattaatg aatttagaca
    43381 aattgccagc aacaggcttc aaacttagtt gctatcctgt caagatcaag aaggcaagtg
    43441 cgggttggat aagagcagtg gcaatgatcg aaaagaaaaa gaaagaataa gccaaaacat
    43501 ctgtatggaa gaaattttcc gatgcagatg tttttcattt tttctttcgg ataccttgac
    43561 atatgaataa ccgttcattt ataattagtt atgaagagat attcatatgt tgaggcgagg
    43621 aggtcattaa aatgaaaagt tacagattag aaggtttaga ttgtgcgaac tgtgcaatga
    43681 aaatcgaaaa aggagttcag aagatcaatg gagtcaagga agcaacggta aacttcactt
    43741 ctggaaaact aacgattgac gcagaggaag atcatttggc tacgattgaa caagaaataa
    43801 aaaaagtagt gaaggaatta gaaccagatg tcaaagtaac agaaatagat aaggaaaaag
    43861 tatctgaaca tggaaatgaa aaagagagaa atacgctgtt ccggatttta ttttcccttg
    43921 caggtatcgc tttattgcta ttatttgatt ttaatgaacc aattcgcttg atagggtatt
    43981 tattgattta tctgctgata ggatatgatg tagtgaagaa ggcagtgatg aatatcgtca
    44041 aaggaaaaat ctttgatgag aattttctta tgtctgttgc tacgattggc gctatgttga
    44101 tcggtgaata tccagaagcc gtagcagtga tgctatttta tcaaatcggc gagtatttcc
    44161 aaggattggc agtcagtcat tcaagaaaat cgattcgcga attgatggcg atccgtccag
    44221 aaacagctca cgtgcagacg acggaaggat tgatgaccgt gaaccctgaa gacgtgcaga
    44281 tcggtcagtt tgtacttgtg aagcctggtg aacgtgtacc gttagatgga acgatcatcg
    44341 aaggagaatc attagtcgat acgtcagcac ttacaggaga atcagtccct aaatctgtat
    44401 atgttggtga aacagtatta agtggattta tcaataaaaa taaaccattt ttagttcaag
    44461 tagaaaaatc ttatgaaaat tctactatca gcaaattatt agaattagta gaaaatgcca
    44521 gcagtaaaaa agcaccagct gaaaatttca ttactaaatt cgcgcgctat tacacaccag
    44581 tcgttgtagg attggccgtt ttattagctg ttttacctcc acttgttgtt tctggagcgg
    44641 cgttttctga atggatctat cgagcattga catttttagt gatctcatgt ccatgtgcat
    44701 tagtgatctc cgtacccctt agtttctttg gcggtatcgg aggagcaagt aaaatcggtg
    44761 tattagtaaa aggttcaaat tacttggagt tgcttgcaca aactgagaca gtggtattcg
    44821 ataaaaccgg cacattaacg aaaggtgact tttcgatcca gacgatcgat acaaaaatcg
    44881 atccaaagat attcatgcaa tatgttgcga gtgcagaaca gttttctaca catccgattg
    44941 ctcaatctgt tttagaaggc tacgcaggtc cgcttttacc aacagctaat atccaagaat
    45001 ttgcaggtga agggatctta gctgaagttg atggcaaaca agtattagca ggtaatcaca
    45061 aattgatgga aagatttgaa atctcttttc cttcaagtca agaaatcggt acattgcttt
    45121 atctagcgat cgatcaaagt tacagtggtt atcttgttat tgcagatacc ttgaaagaag
    45181 atgccgtaga cgcattggtt caattaaaaa aggctggtgt gaagaacaca gtcatgttga
    45241 cgggcgattc gaaaaaaatt gctgatcata tcgggaagca agtaggcgtg gacaagatat
    45301 atagcgaatt gcttccagaa gataaagtgc agcggttaga ggaaatctta caaagaaaca
    45361 ataaaaagac cgcatttgtc ggagatggaa tcaacgatgc accggtgcta gcaagagcag
    45421 atgtaggaat cgcaatgggt ggattgggaa gcgatgctgc aattgaagca gcagatgtag
    45481 tcatcatgaa tgatcaacca tcgaagattg cagaagcaat ccatttagca aagaaaacat
    45541 tgaaaatcgt caaacagaac attgtctttg ctattgggat aaaaattttg gtacttgcct
    45601 taggtgcttt tggttttgca tcaatgggag atgcagtatt tgcagatgtt ggggtgacag
    45661 tattagctgt tttgaatgcc atgcgaagct tgcatgtaaa aaataaacgt tgatcaatga
    45721 agaggacgaa tgaacgtcct ctttttttta tatccttttc ttaatgaaaa atgtaaagaa
    45781 aatagatagg attataaaat aactaatgtt tttaattttg cagaaaattc aaaatagctt
    45841 gaaattcaat aaggtaaatg aaataaaaga aaataactta tttttttgat ggaaaaaata
    45901 tgaaaaaacg atgtgtatta aataaaagaa tacacacata aaataacact gtcttgtaag
    45961 tttgttaaaa attgaatatg attacatctg gataacaaat ttttatcata aaggagagaa
    46021 cgaatgaaca acaaacaatt acgctggttt actgttgcgt taattgcatt taacatggtt
    46081 tggggcatgg ggaatgtagt taataactat gctcagcaag gagtatcagt tgtcacctct
    46141 tggctattga ttttggccat ttattttatt ccatacgcat tgatcgttgg acaattaggg
    46201 tcagccttca aggatagtaa aggaggcgtc agttcatggg tcgaaaatac gacatctaat
    46261 aaacgactgg catactatgc cgcttggact tactgggtcg tccatattcc ttatttggca
    46321 caaaagcctc aagcaatcct gattgctggc ggttgggcag tccaaggaaa tggaaatatc
    46381 gtaaatacga tgtcagtaca aatggtagca gttatttcac ttattatatt tcttgccttt
    46441 ttatatttat caacaaaagg actttctact ttgaaagtga ttggcggact ggccggaaca
    46501 gcgatgttcg tcatgtcgat cttatttatt cttttagctg taacggcacc gttcatcaat
    46561 ccaacgatgg aatttgccac accacatatg aatcaagtga aaacatatat tccaacattt
    46621 gatttcagtt atttcacaac cgtttcgatg ctagtatttg cagttggagg agcggaaaaa
    46681 atatcccctt atgtcaactc tacaagaaat cctgcaaagg aatttcctaa agggatgatc
    46741 ttcttagcag caatggtagg gatttgtgct gtattaggct cagtcgcaat gggtatgctg
    46801 tttgctagcg ataatattcc taaagacttg atggcaaatg gggcatacag tgcttttcaa
    46861 attttaggta attactatgg tatcggtaac tcattgatga tcatttacgc attgacaaac
    46921 atgattggac aaatctccgc attagccttt tcaattgatg caccactaaa aatcttgtta
    46981 gcagatgcgg atccagaatt tgtaccaaac tggctacgta aacgtaatcg taaaggtaca
    47041 ttggtgaatg gttatcttct gacaggtata ctagtaggaa tcattatttt gttgccgatc
    47101 tttggtatca aagatatgaa tgaattagta aaatggttga cgaacttgaa ctcagttgtc
    47161 atgccaatgc gttacctatg ggtgttcttg gcatatatga tgttgaataa agcttataag
    47221 aaattcaatt ctgaatataa atttgttaaa aatccaaaaa tcggttttat ctttggtgct
    47281 tggtgctttg ccttcactgc gtttgcatgt atcctaggaa tggtgccaaa agtagattat
    47341 actgctgatc ctaaagcatg gtggttccaa ttattcacga atatcatcac accaattgtc
    47401 ttgatcttat taggtatgat cttgccagca attgctcgtc gagacaaaaa caaagaaatc
    47461 actgaaccag aaacagtggt tcagccttaa aatagaaata cttgttacaa gaggttgtga
    47521 cagaagtggt cagcttcaag aaataagaag gaatttacga aaattgcttc tcaaattttt
    47581 gtgaagtttc ggcttgtttt tcgcagaagc tacttctgga acaccgtgaa tcagaggttg
    47641 tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagc ccctcatatt
    47701 tttcgttttg ctgggcttat taccgcagat gcaagctttt gaacaccgtt taagaaagag
    47761 gtagtgagcc tgccgtttaa ctccgagtca caaggagcaa tttcaaaaaa caacttctca
    47821 tgtttgttga ctattgtgcc ttgtgaccga ggtgttggca ggagaacacc gtttaaggaa
    47881 gaggttgtaa aatcagcgat ttgacctgag tattagagga acaaacgaaa aaatagctcc
    47941 tcatattttg ccgttttttg agttaatgct gaaggtcagc tgattgaaca ccatttattc
    48001 gaaacaaggg actttgacac gacttttgtc acagtccctt gtttttttgc ggcgttataa
    48061 gtggtatgat cgaaccaaat tccaaagaga agtgagggag aagaatgaag atcatcgtga
    48121 ttggacaaag tgggtcggga aaatcgaccc tcgcaaggaa gatcaaagaa atcaccgact
    48181 ttccgctact gccgctagac cttttatggc atacaacaga ctacagtatt caggcaaaaa
    48241 agtggttttt gcaagaacag caatcgttta tggtatctaa tccgtcatgg attgttgaag
    48301 gaaattatac ttctacatta gaggaaagga ttaaagaagc agataagatc atttggctta
    48361 aagtgccgcg ttatctcgcc atctaccgag tagtttggcg ttctctaaaa agaaagataa
    48421 acaaaaaatc tcggccagat atgcctgaat cattttcaga gaaactaaac agggaatact
    48481 tagaattttt atcttttatc tggcattttg aagaaaacaa tgaaccgaaa atacagcagc
    48541 tgatccaagt agctaatgca agaaataaac tgatcatcct taaaacaaga cgagagaaac
    48601 aagaattttt aactaaattg aaaatagaga gcaaaaataa ttgacagttt ttgtttacaa
    48661 gcgtaatctg tattcataag ctaatgatta catttgtaaa cgaaaggtgt gaaataaatg
    48721 gaaaaagtca aaacgccagt aaagatcagt gattcagagt gggagatcat gcgtgttatt
    48781 tggacacttg gacagacgac agcccaagaa atcacgcaga tcttagctga ttcgatggat
    48841 tggaaaccag caacgatcaa aactttgctg ggacgtttgg taaaaaaaga agtgatctgg
    48901 acagaacaag aaggaaaaaa attcatttat catccagctg tctcggagat ggaaacagtt
    48961 cgcagtgcga cggaaaatct tttttcccat atctgtgcaa aaaggattgg agagacgatt
    49021 gcggatctag tagaagaagc cactttgact caagaagata tcaatgagat tttgaaacaa
    49081 ctggaacaaa agcaaccagt agatacgatc gaatgtaact gtatcccagg tcaatgtgaa
    49141 tgtaaacaac atcaatagga ggaagaaaaa atgaaacaac aattttcaat cgaaggtatg
    49201 agctgcaatc attgtgcagc aagagtagaa gaaacagtaa gcgcacttga cggcgtgcaa
    49261 aaagtgaaag taaatttgaa aaaagcaaac ggtacggtca agtttgatga aacaaaagtt
    49321 caatccgaaa agatttgtca agcaatcaat ggattgggtt ataaagcaga ggtgatttga
    49381 tggcaacagc agaaaccaaa atggatacgt tcgtcattac aggtatgact tgtgcaaatt
    49441 gttctgctag gatcgaaaaa gagctgaacg gacaacctgg tgtggtcaat gccacagtca
    49501 acttggccac tgaaaaagca agtgtcaaat atgaagggac gaccactgaa aaattaatcc
    49561 aaagcgtaga aaacatcggt tatggtgcaa ttttgtacga tgaagcccac aaacaaaaaa
    49621 ttgcagaaga aaagcaagcg tatttgaaaa aaatgctatt cgatcttata ttgagtacgg
    49681 ttttgacttt gccgttgatg ttgtcaatga ttgctatgat gttaggaagc catgcggcga
    49741 ttgttcactt ttttcatttt ccaatcgtcc agttagtgct gtctgctcct gtccaatttt
    49801 atgtcggtgc tcgtttttat aaaggtgcgt accatgcaat caagacgaaa gcaccaaata
    49861 tggatgtatt ggtagcaatt ggaacatcgg ctgcctttgc attgagcatt tacaacggat
    49921 ttttccgtgg acacccccaa gatctttatt ttgaaagcag cagtatgatc atcacgctga
    49981 ttttgctcgg caaatatttg gaacatacag caaaaacgaa aacaggtaat gcaatcaaac
    50041 aattgatgtc tcttcaaaca aaaaccgccc aagtgataag aaacgggaaa gaagaaacgt
    50101 tagcgattga agaagtagtc gttggtgatc aactagtcat ccgtcctggt gagcagattc
    50161 cagcagatgg tcgaattatt tcaggaagca gtgcgataga tgaaagtatg cttactggtg
    50221 aaaatcttcc tgtagaaaag aatccggatg acacgctttt tggcgggaca atcaatacga
    50281 atggtctgct acacatggaa gtcacacaag tcggcaagca gacagtatta gcgcaaatca
    50341 ttcaaatggt ggaagatgct caagggagca aagccccaat ccaaaaaatc gcagatcgga
    50401 tctcagggat ttttgttccg atcgtattag tcatcgcgtt tatcacgctc atagctacag
    50461 gtttgatcac tggtgattgg caactcgcat tgatccatag tgtctctgta ttagtcattg
    50521 cgtgtccatg tgcattaggt ttagcgaccc caacagctat tatggtagga acgggtgttg
    50581 gtgcacgaaa tggaatttta attaaaggcg gagaagcatt agaagcagct gctcacttag
    50641 acagcattgt tttggataaa actggaacga ttacagaagg aaagcccaaa gttacagatc
    50701 tagtcggttc aaaagaagtc ctatctattt tttatacttt agaacaagct tctgaacatc
    50761 cactaggtaa agcaatcgtg gaatacggaa aactgcaaga agcagcaaca tacgatatga
    50821 ttgattttac agcccaccca ggtgctggga tcagcggtac gattaatgga gtacgctatt
    50881 ttgcgggtac acgtaaacga ttaattgaat tgaacctatc atttgatgaa taccaagaac
    50941 acgcgttaga attagaacag cagggaaaaa cagtcatgtt tttagctgat gaaaagcaag
    51001 tgatcgggtg gattgccgtg gctgatcaaa tcaaactaga agccaaacaa gcaatcaagc
    51061 agctccagaa taaaggatta gatgttttta tgctgacagg agacaacaaa ctggcagccg
    51121 aaacgattgg taaacaagtt ggtattgatc caaagcatat ctttgctgaa gtacttccag
    51181 aggataaagc agcctacgta gaaaaacttc agaaagatgg caaaaaagtc ggtatggcag
    51241 gcgatggaat caatgatgca ccggccttag cattagctga tgtcggtatg gcaatgggaa
    51301 gtggaacgga cattgcgatg gaaacagccg atgtgacgct gatgaatagc agtttggcat
    51361 ccattgcaca aacaatcgag ttgtctaggt tgacattgag aaaaatcaaa caaaatcttt
    51421 tctgggcttt tgtctataat acgattggta ttccttttgc cgcactaggc tttttgaatc
    51481 caatcattgc aggaggagcg atggcgttta gttccgtcag tgtattgttg aactccctga
    51541 gcttaaatcg acacatgaaa aagtaagaga agggatggag taaaaatgaa tgggaacgat
    51601 atggagaaaa aacatgagca taaaaaagaa gtagtaaaca aagaaagtac agaatctcat
    51661 gaaaaacaga tggagatgaa acatgaccat agtcagatgg atcattccat gcacatggga
    51721 cataaccatg gagatatagc aaacagcaaa caaatggacc attcgatgca catggatcac
    51781 gaacacggcg gcatggatca ttccatgcac atggggaatt tcaaacaaaa attttggcta
    51841 tcgcttatcc tagctatccc aatcattctt ttttcaccaa tgatgggaat ggaatttcca
    51901 tttcaagtaa cgtttcctgg ttctgattgg ctcgtattga tcttagcaac tatactattt
    51961 atctatggcg gtcagccatt tttaagtgga gctaagatgg aattgaaaca aaaaagtcct
    52021 gctatgatga cactgatcgc gatggggatt acagttgcat atatttatag tgtctattcg
    52081 tttatcgcaa atctgctcaa tccacataca cacgtcatgg atttcttctg ggaattggct
    52141 actttgatcg ttattatgct actaggtcac tggattgaaa tgaatgctgt gtcgaatgcc
    52201 agcaatgctt tacaaaaact agcagaatta ctgccagaat cagtgaaacg cttgacgaaa
    52261 gatggaaaag aagagacagt ttcattgaaa gaagtaaacg aaggtgatcg tttgatcgtc
    52321 cggtctggtg ataaaatgcc aacagatggt gtaatcttga aaggtgaaac aattgttgac
    52381 gaatcagctg tgactggcga atcaagagga atcaaaaaac aagccaatga caaagtgatt
    52441 ggcggttcta tcaatgggga tggaacgatc gaaatcgaag taactggaac tggtgaaaat
    52501 ggttatctag cgaaggttat ggaaatggtg cgaaaagcac aaggagaaaa atccaagcta
    52561 gagtcattat ctgacaaagt ggcaaaatgg ctgttttatg tcgcattaat tgtgggtatc
    52621 ctggcattca tcgcctggtt gttcttgaca gatcttccta atgcattaga acgtatggta
    52681 acagtcttta tcatcgcctg tcctcatgct ctaggtttag ctatcccatt agttgttgct
    52741 cgctccacat caatagcagc taaaaacgga ttacttttga aaaaccgcaa tgcactggag
    52801 caagccaatg atctagatgt gatcatgctg gacaaaacag gaacactaac agaaggaaaa
    52861 tttactgtaa cgggtgtcga agtacttgat gatgcgttca ataaaaatga aatccttcaa
    52921 tatctaggag ccttggaagc gaatgccaat catccattgg ctgttggcat tatgaattat
    52981 ttgaaagaac atgaaatcaa gccttatcaa gctgaaaatc taaaaaatct ttcaggagtc
    53041 gggctagagg caacagtcaa aaaacaacaa gtgaaaatag ttaatgaaaa agaagttgag
    53101 cgtctcggat taaacgtaga acaagcatta ttgaaacctt accaagaaca aggaaatacc
    53161 atcagcttcc tgattttaga aaatcatcta gctgcaatcg ttgctttagg tgacgtagta
    53221 aaaacagaag caaaagaatt tatccgaaca ttgaaagaaa gaaaaatcac tcctgtcatg
    53281 cttactggtg acaataaaaa cgctgcccaa gcagtagcag attatttagg gatcgaagaa
    53341 tattatggcg gtttattacc agatgataaa gaagctgttg tccagaaata ccttgaccaa
    53401 gggaaaaaag taatcatggt gggtgatggg atcaatgatg cgccaagttt agcccgtgct
    53461 tcaatcggga tggcaatcgg tgcagggaca gatatcgcaa tcgattctgc ggatgtcgta
    53521 ttgacaaaca gcgatccaaa agatattttg cattttcttg atctagccaa gcaaacgcga
    53581 aagaaaatga tccagaacct ctggtggggg gcaggttaca atattcttgc aattccgcta
    53641 gcagccggaa ttcttgcgcc aattggtatc atattaagtc cagcagttgg tgctgtcttg
    53701 atgtcgttaa gtacggtagt tgtagctcta aatgctttga cattgaaaat caaataataa
    53761 tgaaaaaag
//
LOCUS       DACGMI010000013        52445 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.013, whole genome shotgun sequence.
ACCESSION   DACGMI010000013 DACGMI010000000
VERSION     DACGMI010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.013"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            1..794
                     /locus_tag="IXT46_000895"
                     /pseudo
     CDS             1..794
                     /locus_tag="IXT46_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
     gene            934..1860
                     /gene="cysK"
                     /locus_tag="IXT46_000896"
     CDS             934..1860
                     /gene="cysK"
                     /locus_tag="IXT46_000896"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAQ4946829.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2096..2542
                     /locus_tag="IXT46_000897"
     CDS             2096..2542
                     /locus_tag="IXT46_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4946830.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2814..4166
                     /locus_tag="IXT46_000898"
     CDS             2814..4166
                     /locus_tag="IXT46_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4946831.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSDPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQEALGEIETAQ
                     "
     gene            4337..4624
                     /locus_tag="IXT46_000899"
     CDS             4337..4624
                     /locus_tag="IXT46_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946832.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            4850..5293
                     /locus_tag="IXT46_000900"
     CDS             4850..5293
                     /locus_tag="IXT46_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4946833.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5299..6483)
                     /locus_tag="IXT46_000901"
     CDS             complement(5299..6483)
                     /locus_tag="IXT46_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAQ4946834.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6751..7449
                     /locus_tag="IXT46_000902"
     CDS             6751..7449
                     /locus_tag="IXT46_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAQ4946835.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7456..8133
                     /gene="nth"
                     /locus_tag="IXT46_000903"
     CDS             7456..8133
                     /gene="nth"
                     /locus_tag="IXT46_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAQ4946836.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8259..8792)
                     /locus_tag="IXT46_000904"
     CDS             complement(8259..8792)
                     /locus_tag="IXT46_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946837.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9089..11470)
                     /locus_tag="IXT46_000905"
     CDS             complement(9089..11470)
                     /locus_tag="IXT46_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAQ4946838.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11460..12107)
                     /gene="recU"
                     /locus_tag="IXT46_000906"
     CDS             complement(11460..12107)
                     /gene="recU"
                     /locus_tag="IXT46_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAQ4946839.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12171..12710
                     /locus_tag="IXT46_000907"
     CDS             12171..12710
                     /locus_tag="IXT46_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAQ4946840.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12800..13219
                     /gene="gpsB"
                     /locus_tag="IXT46_000908"
     CDS             12800..13219
                     /gene="gpsB"
                     /locus_tag="IXT46_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAQ4946841.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13241..13608
                     /gene="rnpB"
                     /locus_tag="IXT46_000909"
     ncRNA           13241..13608
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="IXT46_000909"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13817..14983
                     /locus_tag="IXT46_000910"
     CDS             13817..14983
                     /locus_tag="IXT46_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAQ4946842.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15029..16525
                     /locus_tag="IXT46_000911"
     CDS             15029..16525
                     /locus_tag="IXT46_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAQ4946843.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     LLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16606..17289
                     /locus_tag="IXT46_000912"
     CDS             16606..17289
                     /locus_tag="IXT46_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4946844.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            17934..19124
                     /locus_tag="IXT46_000913"
     CDS             17934..19124
                     /locus_tag="IXT46_000913"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAQ4946845.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19226..20179
                     /locus_tag="IXT46_000914"
     CDS             19226..20179
                     /locus_tag="IXT46_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAQ4946846.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20248..21597
                     /locus_tag="IXT46_000915"
     CDS             20248..21597
                     /locus_tag="IXT46_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4946847.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGRAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21780..22103)
                     /locus_tag="IXT46_000916"
     CDS             complement(21780..22103)
                     /locus_tag="IXT46_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946848.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22232..23395
                     /locus_tag="IXT46_000917"
     CDS             22232..23395
                     /locus_tag="IXT46_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946849.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23465..24814
                     /locus_tag="IXT46_000918"
     CDS             23465..24814
                     /locus_tag="IXT46_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAQ4946850.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(24859..25289)
                     /locus_tag="IXT46_000919"
                     /pseudo
     CDS             complement(24859..25289)
                     /locus_tag="IXT46_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            25677..28319
                     /gene="alaS"
                     /locus_tag="IXT46_000920"
     CDS             25677..28319
                     /gene="alaS"
                     /locus_tag="IXT46_000920"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAQ4946851.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28519..29115
                     /locus_tag="IXT46_000921"
     CDS             28519..29115
                     /locus_tag="IXT46_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4946852.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29237..30385
                     /locus_tag="IXT46_000922"
     CDS             29237..30385
                     /locus_tag="IXT46_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAQ4946853.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30423..30836)
                     /locus_tag="IXT46_000923"
     CDS             complement(30423..30836)
                     /locus_tag="IXT46_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAQ4946854.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            30915..31346
                     /locus_tag="IXT46_000924"
     CDS             30915..31346
                     /locus_tag="IXT46_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAQ4946855.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31445..31678)
                     /locus_tag="IXT46_000925"
     CDS             complement(31445..31678)
                     /locus_tag="IXT46_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAQ4946856.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            31861..33531
                     /locus_tag="IXT46_000926"
     CDS             31861..33531
                     /locus_tag="IXT46_000926"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAQ4946857.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33678..34064
                     /locus_tag="IXT46_000927"
     CDS             33678..34064
                     /locus_tag="IXT46_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946858.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34051..34749
                     /locus_tag="IXT46_000928"
     CDS             34051..34749
                     /locus_tag="IXT46_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4946859.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34754..35218
                     /locus_tag="IXT46_000929"
     CDS             34754..35218
                     /locus_tag="IXT46_000929"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAQ4946860.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35215..36126
                     /locus_tag="IXT46_000930"
     CDS             35215..36126
                     /locus_tag="IXT46_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAQ4946861.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36361..36900
                     /gene="pyrR"
                     /locus_tag="IXT46_000931"
     CDS             36361..36900
                     /gene="pyrR"
                     /locus_tag="IXT46_000931"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAQ4946862.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            36914..38197
                     /locus_tag="IXT46_000932"
     CDS             36914..38197
                     /locus_tag="IXT46_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAQ4946863.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38210..39136
                     /locus_tag="IXT46_000933"
     CDS             38210..39136
                     /locus_tag="IXT46_000933"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAQ4946864.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39155..40435
                     /locus_tag="IXT46_000934"
     CDS             39155..40435
                     /locus_tag="IXT46_000934"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAQ4946865.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40440..41516
                     /gene="carA"
                     /locus_tag="IXT46_000935"
     CDS             40440..41516
                     /gene="carA"
                     /locus_tag="IXT46_000935"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAQ4946866.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41521..44706
                     /gene="carB"
                     /locus_tag="IXT46_000936"
     CDS             41521..44706
                     /gene="carB"
                     /locus_tag="IXT46_000936"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAQ4946867.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44760..45536
                     /locus_tag="IXT46_000937"
     CDS             44760..45536
                     /locus_tag="IXT46_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAQ4946868.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45533..46465
                     /locus_tag="IXT46_000938"
     CDS             45533..46465
                     /locus_tag="IXT46_000938"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAQ4946869.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46462..47178
                     /gene="pyrF"
                     /locus_tag="IXT46_000939"
     CDS             46462..47178
                     /gene="pyrF"
                     /locus_tag="IXT46_000939"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAQ4946870.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47185..47814
                     /locus_tag="IXT46_000940"
     CDS             47185..47814
                     /locus_tag="IXT46_000940"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAQ4946871.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47802..48116
                     /locus_tag="IXT46_000941"
     CDS             47802..48116
                     /locus_tag="IXT46_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946872.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48154..48795
                     /locus_tag="IXT46_000942"
     CDS             48154..48795
                     /locus_tag="IXT46_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4946873.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            48826..49530
                     /locus_tag="IXT46_000943"
     CDS             48826..49530
                     /locus_tag="IXT46_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAQ4946874.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            49527..50429
                     /locus_tag="IXT46_000944"
     CDS             49527..50429
                     /locus_tag="IXT46_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4946875.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50587..52293)
                     /locus_tag="IXT46_000945"
     CDS             complement(50587..52293)
                     /locus_tag="IXT46_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAQ4946876.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        17146 a         9140 c        11267 g        14892 t
ORIGIN      
        1 ggaacgagtc ttttagttgg gccgatgatg gttacagcgg taccgcaaca tgttcatgca
       61 gatgaacaag gatctcaaac agttgctgat cctcaagcgt ttatcgatca aatcggctgg
      121 tctgcgtcag aagttgctgc aagtaatgac ttgtatgctt cagtcatgat cgctcaagcg
      181 ttgttggaaa gtgcatatgg cacttccgga ttagctagtg cgccaaatta taatctattc
      241 ggtgtgaaag gaagctataa cggacaggtc gtttatatgg caaccaaaga atatgtaacg
      301 gacaatgggt aacgatgaat gaaccattcc gaaaatattc ttcttattgg gaatccttcc
      361 aagaccatgc gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg
      421 gcgtgtggaa aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt
      481 atgctaccga tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa
      541 cccgttttga tacgccatca acaggttcgg ctaccacaag tacaacaaca acgactacta
      601 cgacgacttc aacgtcatca tcttcaacaa cagatgtaaa tacaaataat ggtcagacat
      661 atacagtcgt gtcaggtgat acgctatggg atattgcaca aaaatttggc atgtctgttg
      721 atgatctaat ggcgaaaaat ggcatgtcta tgtccagtta ttctttatta gttggtcaag
      781 aactaaacgt ttgatttaga taaaaaggca aagaaactac catatatggt atatctttgt
      841 cttttttttg ctagtcaaag acgaatcact cgccataaat gaacagattg tattatgata
      901 agtaagaaga gcaaagacaa ggaggaattg aagatgacag ctatctataa ctcagtcacc
      961 gaattgattg gcaaaacgcc aatcgtcaaa ttaaataaaa tcgtaccaga agattcagca
     1021 gatgtttttg taaagcttga gttttttaat ccaggaggaa gtgtaaaaga tcgtattgct
     1081 ttaagtatga tagaaaaagc agaacacgat ggtctactga aaccaggtga tactatcatt
     1141 gaacctactt ctggaaatac aggaatcgga ttgtcgatgg taggagttgc aaaaggatat
     1201 aaagtaatca tcgtgatgcc tgagacgatg agtatcgaaa gacgtttatt gatgaaaggg
     1261 tacggcgcag agttgatttt gactcctggt gcggatggta tttctggatc aatcagagaa
     1321 gcagaacgtt tggcaaaaga aaacggctac tttttaccat tacaatttga aaatgaagca
     1381 aatcctcttg tgcatgagaa gacgactggt cctgagatac atcaagcatt tggagtaaat
     1441 ggcttggacg cgtttgttgc aggtatcggt acaggaggaa cgatcactgg cgctggccga
     1501 gaattaaaac gtgtgtatcc gaaaatcgaa ttaatcgggg tagaaccagc agaatctgct
     1561 attttagaag ggaaagaagc gggacctcac aaaatccaag gaatcggtac aggttttgtt
     1621 cctaaaacac tggatacttc tgtgtatgat aaagtccttt ctattagtgg agacgaagcg
     1681 atggaaacag ctagagaagt tgggcgaaaa gaagggattt tagtaggcat ctcatctggc
     1741 gctgcaattg ctgccgcgct aaaagtcgca aaagaattag gaaaaggcaa gaaggtatta
     1801 gctgtggttc ccgacaatgg tgaacgttat ttatctacag ccctttacca agagatataa
     1861 ggcacttggt ttttctccag ataggtttat gtaaaaaact tttaaagatg aaaagaacac
     1921 acaaaaattt atgatgagaa aaattatttg aatagagacg taaaatagtg aacgcgactg
     1981 ttttacgtct tttttcatta aaatacaata aaattgaatt ttcttttcat gttaagtgga
     2041 ttttaaaatg taaaaatagt atgataagac gagaataaca acgtggggtg tttacatgga
     2101 aaataagtta gtcgaagagg ttatcgaaaa gttaaaaaaa gagaacattc gaatcacacc
     2161 tcaacggtac gcggttttag aatatttgat tgaacatcat tcccatccaa cggctgatga
     2221 gatttataaa gcacttgaac atcggtttcc aaatatgagt gttgcgactg tttacaataa
     2281 ccttcgctta tttacttcga ttggatttgt tcaagaaatg aagtacggcg atgcttctag
     2341 ccgatttgat ttcagttcaa agcgtcatta tcatgtaatt tgtgaaaact gcggtaagat
     2401 tgttgatttt cattacccag ggcttgaaga tatagaaatg gctgcgagca gactgactga
     2461 ttttgagatt aatgaacatc ggttggaatt gtatggactc tgtccggatt gtaaagagtc
     2521 agcaaaaaag gcgcaaatgt aaaaacagtt tctataagtg ttatacctaa aaaaagctag
     2581 ctgtgtaaaa aaacgctagc ttttttattt ttttgtcttt tattcacaat cttagatatc
     2641 aaagtgaata ttatcacaat aagaatcttg tagatattgg gttcttatgc ttgaaaagga
     2701 atgaaactac aaacaaacct ttgtgaattc acaagcatta aactgttgta tccgttttat
     2761 ttctgttata gtagttttgt cgaaggacaa aatgttaatc ggagggacca taaatgaaag
     2821 tagtagtaat tggctgtact catgcaggta ctgcagctgt aaaaagtatt ttaaaaaatc
     2881 atccagaagc agaagtgaca gtatatgaaa gaaatgacaa tatttctttc ttatcttgcg
     2941 gtatcgcact ttatgtcggc ggagtagtaa aggacccagc aggcttgttc tactcaaatc
     3001 ctgaagaatt atcttcatta ggagcaacag ttaaaatgga acacgatgta acagacgtcg
     3061 atacagaaaa taaaacagta acggcaaaag atctgaaaac aggagaaaca gaaacggttt
     3121 cttatgataa attagtgatg acaactggtt catggcctat tatcccaccg attagtggaa
     3181 tcgatgcgaa aaatgtactc ctatgcaaaa actacaatca agcaaatgaa attattgcac
     3241 aagcgaaaga agcaaaacgt gtagtaattg ttggtggtgg atatatcggt attgaattag
     3301 tagaagcttt tgtcgaatct ggaaaacaag tgacattgat tgatggatta gatcgcatct
     3361 tgaataaata tctagataaa ccattcacag atatcttaga aaaagaattg acagaccgcg
     3421 gtgttactct tgcgctaggc gaaaatgtta ctgaatttat cacagatgaa gaaggaaaag
     3481 tgaaacaagt agctacacca acagatacat ttgatacaga tatggtcatt ttatgtgtgg
     3541 gcttccgtcc aaatacaaaa ctgatcgaag gaaaagtaga tacactgcca aacggggcaa
     3601 tcaaagtgaa tgaatacatg cagacaagtg atccagacat ttttgcagct ggagactctg
     3661 cagtagtcaa ctacaatcca agtggcacgc aaaactatat tcctttggca acaaatgccg
     3721 ttcgtcaagg tttacttgtg ggaaataact tgacagatca taaaatggcg tatcgtggta
     3781 ctcaaggaac ttcaggactt tacctatttg gctggacgat cggttcgaca ggtgtgacca
     3841 aagaaagcgc aactttgaac gatctagaag tccaagcgac tgtatttgaa gataattatc
     3901 gtccagagtt catgccaact actgaaaaag taatgatgga gctagtctat gaaaaaggaa
     3961 cgaatcgtat cgtaggtgct cagttcatgt ccaaatacga cattacacaa tcagcaaata
     4021 ccatgtcttt agctgttcaa aataaaatga ctgtagaaga tctcgcactt tcagatttct
     4081 tcttccaacc acattttgac cgcccatgga attacttgaa cctacttgca caagaagcgc
     4141 taggcgaaat cgaaactgca caataaagaa aaagggttgt gacacaattt tgtcacgacc
     4201 ctctgtcttt ttttgtgaaa agtacaatta gttgtctttc ttcgaatttt ttgtcacaat
     4261 aagcagcaaa gataaagctg ttacataaaa gaacaagcag ctttatttga ttttgaaaag
     4321 aaaggtgaga aagaagatga ataaagaata ttttgtccaa caagatgcat ttttagaaga
     4381 ttataaaagt gcttcgaaga aattaacgat caatattgat gagttggcag atcaagtact
     4441 ctctcagttg aatgaaacgc aagaggaata ttacacgatg ccagcaaatg acgccaaaga
     4501 taatgtttct catcgttttc ctttcagtag acgcatctac tcagatgaaa atgacggcac
     4561 attgaataca gagtacacat atgaaggtca gccatatgtg ctagaaactg atgatgatct
     4621 ttaaagacag tttttgaaaa ggccgctcat ccttaagtga tgacaaaaaa tcatcacaat
     4681 taccgatgac tgtctcttta ctatctttta atcagaaaaa ggggttatga caagctttgt
     4741 caaccccttt ttttcttggt ttcagattgg gttttcctac aaaatatttt tatctttgtt
     4801 gaataggaaa caaaaaaaca atataatgaa agaaaaagaa ggtgtagaaa tggataaaag
     4861 acaactgcta atagaagaat atctggattt agctaatgag attattcatc gtaataaacc
     4921 agaaatggaa aaagaatttg caggatttac tctaaatgaa ctagaagtga ttgaacatat
     4981 cgggaaaatc cctgatccta acgtgacaaa attagcgaat gctagttaca tgactagagg
     5041 agccatcagt aagctaacaa aaaaactgat agctagaggg atcataaaca cttatcaaag
     5101 cgaagagaat aaaaaagaaa tctattttca attgacgcca atcggacaaa aaataaggaa
     5161 tagacacgag caactccatc aaaaatgggt acagcgagat gctactgtat ttgaaaatat
     5221 gtcaaaagaa gaatttgaca cagtatttcg ttttatcggt cgatacagag aatttatacg
     5281 aagtagcaaa tgaagctact attttttatt gtagtgataa taggcaaaaa tcataagcaa
     5341 aaatccgaat accgtcggaa gaaatggtgc tgcagcataa agctgtcctg cgattagcgg
     5401 gccgatgacg cgcgatagag attgtatact ttgggtaccg cccattacaa gaccttgctg
     5461 gttatctgag acagaattgg atagttggcc attgaataca ggagtaaaaa tagaatcacc
     5521 gaaaccataa cagataatcc caaataaaaa caaaatcggc agtagaagaa ttccagataa
     5581 tgtgatgaat agataggcga ggatttcact gaacatccct attcttgtga tctgctgttc
     5641 tgaaaatttt ttgagcaatc gaggcataat gaacaattgc gagacagtat ccaagattcc
     5701 aatcaaagag aagcttaaac caaccaaccc agccttccac tgaaaggcgt caatcgaaaa
     5761 ttgagaaaag atagattgaa gagagccagc tgccaaccaa acagcaaaac ctgctgtcaa
     5821 taaaggaata acggatgaaa tcttgaataa ttgttgtaat tggtgaaaag gtcttacatg
     5881 ggagaaactt aaatctactg aacgtttttt tattggaagg ctttctagca taaatgtgta
     5941 gccataaacg gcatttaaga aagtaaagag tgctccaata aatataggaa cagaattccc
     6001 caactcagct aatagacccc ctataatagg acccagcgtt gttcctatac cgactaaagc
     6061 acccatccat ccaaaaactt tggttctttc attaggttcc gtgatgtcgg caaagtaagc
     6121 atataaggtg gagatttctc ctgccgtcaa tccttcaatg atacgaccaa ggaacaacat
     6181 ccatatcgaa tttcctaaac caaaaagcaa atatccgata cttgatccta ataaactgat
     6241 aataaggatc ggatgacgcc caaaatgatc acttaagcta ccgagaatgg gggcagataa
     6301 gaaggcagct agagcataaa cagacatgag caaagtgata tagaaagctt gctgatgtat
     6361 ggagtgagaa taaggcagcg ttaaaaacgg aagtacagga ctgacgatag taaatcctaa
     6421 tccagtgaat aagacagaga cgtatccaaa aactttagaa tgtttatttg tgaaactgta
     6481 catgtaaaaa ctcctttatg caataatgtt aacttggaaa caaaaatagt gtatagtaat
     6541 tttgtttcct tgtcaacatt ctaaggaaca gcgaaatcta cttaatttat ttattccgaa
     6601 aagtgaagat acgcatcaaa aacatgaaca aacaaaaatc aagtagacga cattgtaaat
     6661 ctgaccgatc agtgaagtaa atagaaaaga aacctgttct tgcttcccat gtttttttta
     6721 cgtatactgt gattgagcgg aggagaaatc atgttgaatt tagaaaatta cttaagcgct
     6781 ggacaaacag tcatatctaa tcttttactt aaaaattatc ataggatcgg tctacaatct
     6841 gaagaatttt tatttgttct acagttgcat atggcacagc ttgaaggaga tactttccct
     6901 gatttgcaga tgattgctat ggatatggga atcaaacaag atcagatttt tcaaatactg
     6961 gatcgtctcg taacaaatgg atttatcaag atagaaacga cgattgtcaa cggtaaaaaa
     7021 gcagatcgat ataatcttta ccccatctat gatctattag gtgagtattt aaaaacacaa
     7081 gaaaaaaaat acgaagaaaa aacacaagaa aaagaaatcc agtcagtgta tcaattattt
     7141 gaacaagaat ttggacgccc gctttcttcg atcgagttcc agcggatcgg acaatggcta
     7201 gaagaagacc attatcagcc ggaaattttg aagctagcac tgcgggaagc cgtattaaat
     7261 caggcttata gttttaatta cgttgaccgc attttgctat cgtgggaaag aaaaaatcta
     7321 cgtacaaaac aacaagtgga agaagaccaa aaacgaagaa aacagcagct tcttcaaaga
     7381 gaagtagaac agtcagctca acaagaagaa ttgccgaaag tctcactgaa aaattggttg
     7441 gaggagtagc ggaatatgtt aagcaaacaa aaaacaatgg aagctctaga aacgatgtat
     7501 ggaatgtttc ccgaagcaca tggagaactc aagcacaata atccatttga gttattgatt
     7561 gcagtgatct taagtgccca ggcgacagat gtatcagtga ataaagcaac gccagatttg
     7621 tttgcctctt ttccgacacc cgatgcgtta gcagaagctt caatcgatga aatcattctt
     7681 aaaataaaaa cgattggttt gtatcgaaat aaagcaaaaa acatcaaagc gtgtgcacag
     7741 cagctgattg aacgtttcga tgggcaagtg ccaacgtcaa gagaagaatt gatgtctctt
     7801 cctggtgtag gcagaaagac agcaaatgtc gtattggggg atgcattcgg gataccagca
     7861 atcgcagtag atacccacgt ggaacgtgtc tcaaaacgcc tgaggatctg caaactagat
     7921 gctacggtca tggaagtaga agaaacactg atgcggaaag taccacaaga attatgggta
     7981 aagacacatc atacactgat tttttttggt agatatcatt gcacggcaag aaatcccaag
     8041 tgcgaggtat gtcctttgct atcaatatgt caagatggga aaaatcggat gcgtctaaaa
     8101 gaaaaggcgc taaaaaagaa accacgcctg tagacgtggt ttctttaatt gcaaataaat
     8161 gtatgaatta tcttgttatt atggagaaaa gctgtttcgt ttatcttttt tgcatgaaaa
     8221 agtaaatgta catactcagt agctaggatg gtaacttatt acaatttatt gcgataaaaa
     8281 taaaagttgt tatttttatt gggaaaatac ccgatgtaga aaataatgcc ttccaatata
     8341 cctataaaat aagtccagta ttccaaagga ttatataaat aagtgacgta tctatctaaa
     8401 ggtgtaataa aaatgataag tgataataaa aaaataccat ttataactaa acataaacta
     8461 atggatttgg gcggtttcag gctcatcaga aaaatataga ttctggtgaa caacaaccat
     8521 aaaaaagtga gaatcattgc atgagagctt ctttccataa attttccttt aagagtagtg
     8581 cttaaaagta cagaaaaaat aataaatgca aggataggag caattaaagt aaatttattt
     8641 aataataaac aaaatttttc agctttttta ttcttggaat aacgaggtat tgttttcgat
     8701 aaaaaaagat ggtgcagaca aattatgata attaagcata ctatcagata actcaaaatg
     8761 aagccttctt tcaaaaaatt attcaaaacc atatattgta ttttttattt gataataaca
     8821 atgggattat taagaagtgg cactaaataa aagactagtg tgtatttagc cgatttaatt
     8881 ataaacaagt aaatggataa agtatatgta atgataaaag aaaaatggat tttctaattt
     8941 ttaagctaaa tgttagatca cacatgtata tgctggatag tcttataaaa aatcatgtaa
     9001 tacagcttgg tacatgattt ttatttgtag ctgtttttta catagacaca aaaaagaaac
     9061 cacgcttgta gacgtggttt cttttttact atctgtttcc agaagctgag gtgctgctgg
     9121 atggtgtatg gtcatttgca gcatccgctc cgctagttgc tggctcactg gaagaagcag
     9181 gaggagcaga tgaagacggt gtcgagcttt cttcggatga agaagaagga accgttgttg
     9241 aagacgctgg ctcgcttgtt tctgctgtcg tgctttcttt tgaggactca gcagttgatt
     9301 cgctttgact agtagagcta gagctttgag tcgttgtctc tgttgttgag cttccaggag
     9361 tctggacata gctggaagat ggaatagttg ttgatggtgt aattgcattc gatctagctg
     9421 tatattgatc tttgtagtac agttcaccgc ccacacgaat taatccgctt ggcatctccc
     9481 agtctgtatt tgtcacgtta gctgaaacat actgcataag ctcgcgataa acatcagagg
     9541 ctacgtgtga cgattctgaa gtgacaggtg tcattttttt attgtaacct gtccacacgg
     9601 aaatcgaata atttggcgta tagcccgcaa ataggatatc tggatacacc ccagaagaaa
     9661 taccaagttt tgcatactcg tcatctgtgt aattggatgt tccggtctta ccggcttgat
     9721 ataacccagc gatttgcgca ttcgtaccag ttccttcagt gatcgtatct tttaaaatgt
     9781 ctgtgatcat ataagctgtt tctggagaca tggctgtttt tccatctggc tcataagttt
     9841 cttctgttcc gtcttggaag acgattttat taacatattg aggtttgtaa taagtccctc
     9901 cattggcgaa agccgcatag gctgctgcca tttttaagga agaagctccg tattttgtcc
     9961 catcttgttc ttccgtatta ctagagatcg cattcgattg atggatcgta ctgtattcga
    10021 tcccaagatt ttttaagaaa gaagccactt tatctgaacc gacttcattg aataatttga
    10081 ctgctggaac attacgggat aagtaaagtg cttggcgtaa agtaatggtg cccatatatt
    10141 gattatccca gtttcctaca ggagtcgaag tcccttcata gttatacggt gcgtcagtaa
    10201 tagtttttcc agtagaatat ttcaaatatt caaaagctgg tccgtaatct gtgacaggtt
    10261 tcatcgtaga accaaaatca cgggaagtat tcactgctaa gttgttgcct aaagttacgt
    10321 cttctgcgat gtgacgtccg ccaatctggg cttttacttt cccggtattg gtgtcgataa
    10381 gggtggaggc aacttgcatc tcgtcgtctg ggtaagagac atactgatcc gtgttgacga
    10441 tatcatatag tttcttttgg gcgtccagat ccaaattcgt ataaatctct aaaccgtctg
    10501 tgtagacatt cttatctgtt ttttcttgta cttcattgat gacttctttg acataattat
    10561 cgacgatctt agtattgtca tcggattgag ttagttcttg cagaccatcc gttaccggta
    10621 cattaacagc ttgatcatat tctgtttgag agattttttc gttttgaagc atcgtataca
    10681 aaacagtatc tcgtcttttc ttcgcctgat ctggataaac ataaggatca taggcggaag
    10741 gggcttgagg catcccagca agcaatgctg tttgcggtaa agaaagttct gataatttct
    10801 taccaaagta catctcagaa gctgtctcca tcccgtacaa gccgtttgac atatacactt
    10861 tatttacgta gtaggtcaag atctcttgtt tcgatttttt ttgttccaat cttacagcca
    10921 tccacgcttc ttgggccttg cgtttcagag tctgatcctc ggcactggtg gagaagaagg
    10981 aaagtttgat caattgctgt gtcaaagtac ttccgccttg cagtccgcca gaggtaaagt
    11041 tagagagggc agaaccgatg atccgaatag ggtcaacccc gatgtgttta taaaaacggc
    11101 gatcttctac cgacacgatc gcatcttcta atgttttcgg taattcattc gcagaaattt
    11161 tttcacgctt ttctgcgcct aaatcttcga atagttcgcc atcttgtgta tatagtttgg
    11221 aagatacggt agcgtctaat tttttatccg tcaattcggg cgcatctttt gcgtaatacc
    11281 agaaaagtcc tacacctgct aaaaagagga tacagaaaaa tgagagtatt cctaaaagga
    11341 tcttgataaa taatcctttt ttatgtgttc cagaggactt tccagaacct ttgccagaat
    11401 tcttcttcac actcttttta ggagtaggct gtttctgtcg tctagagctt ctagtttgtt
    11461 catttgccat tcttgctttc tccttcaata gataatgttg ataaatagaa gtcaaccgcg
    11521 tccaaataag gaatccgcgg agaaatacca gttttgatct ctattcctag ttcttcgatc
    11581 aaagataaag gtagtgattt gcgtcctttt tccttttggg cgtcccagta agcaatcaaa
    11641 tgaacactat tcaaataaaa acagcgcttc aaagacgaaa accataacaa gacaaagcag
    11701 accccatttt gttcgaggca tgctttcata tgttcgattt gatgggcatg gaagttttta
    11761 aagggaaaag atgttttgtt cttggtttct tttgcttcaa agtccaagta aaagcctcga
    11821 tagacgccat tatagtctgt agttgaggct tgggtaaagt aggcttcctt gatcacagca
    11881 gcacttctct taggatagtc tactttcacg atttggatag gggtaggctt tttatggata
    11941 accgccaacc cgcgggaaag ataatattta ttactttcat tgattgcttc ttcaaagcgc
    12001 atcccccgat tgccgaattc agtgatctga tttctttttt cttgaatttt ttcgacggga
    12061 gaggcattct tataataagg ttggccattt ggatagcgca ataccatctt taatcacact
    12121 cctaggccac attatagcaa aaaagcggat agaaagaaaa ggaatctgag atggataagt
    12181 caaaagtaat ctatgtgtct gggtatcgaa gtttcgaact cggtgttttt aaagaaaatg
    12241 atcctaaaat ccaagttgtt aaaaatgttt taaaaaaaga actccatcag ttagcagaag
    12301 aagggctgga atgggtactt gtcagtggga atttgggcgt cgaactatgg gctgtgcaaa
    12361 tagtagcgga attgaaagaa gaatatccgg aactatctct tggtattttg tatccttttt
    12421 ctgattttgg taataactgg aatgaaggga accaagaaaa aaaacaatta gcagaacaat
    12481 tagcagatta tgtcgaagct gttagccatc aaccctacca atcacctagt cagctaaaga
    12541 atcacactcg ttttatactt gagcatacag tgggctgtct gctgatctat gatgaagaat
    12601 tccctggaaa aacgaagtat ttttttgaag atgcacagaa ttaccaagca gatcatccct
    12661 acgaaattcg gctgatcagt atggacgatc ttcaaaattt tagtgaataa tcgatattgt
    12721 gtttgattta tcaacttttt tcctatacaa tgaaaaaggt agaaatgtta ttacgtaaat
    12781 gaaaactaga ggtgtaaata tggcgaattt ggtttatagt cctaaagaca ttttacaaca
    12841 agaattcaaa acaaaaatgc gcggctatga tcccgttgaa gttgatgaat tcttagacaa
    12901 tatcatcaaa gattatgaaa cttacagcaa agaactcctt gctttacaag aagaaaacga
    12961 tcgattgagt gcaaaagtag ctcaattatc taaaactcaa ggagcagctc aaacacgcgt
    13021 gcaacaaaca gaggcaccaa agagcgcagc agtgaccaat tttgatatct taaaacgctt
    13081 gtcaaatctt gaacgtgaag tatttggtaa aaagcttgat caacaagcaa gtgcagtcaa
    13141 accagcacaa cctaatccaa ataactacac aaatgcagac acaagcttag atgataatga
    13201 aaaaacacgt caattttaat ttttgattaa tgaatttgcg gttttcgggt aatcgcggtc
    13261 tgacttgatc aggctgagga aagtccatgc tcgcacaggc tgtgatgcct gtagtgttcg
    13321 tgcttagcga aaccataagc taaggtactc tttggagtaa cggcaggaaa acaagctaag
    13381 gcttcggcta tgcttaagta tccttgaaag tgccacagtg acgaagcggc tggggaaacc
    13441 catccggtgg aacgcggtaa acccctcgag cgagcaaccc aaacaatggt aggggcgctt
    13501 tttgtctgga agaagaacag gacaaaaagg cagtataact gcagatagat ggttaccgct
    13561 ttgttttttc tccctggaaa agcaaagtac agaacatggc ttatagaaaa ccgcaaacat
    13621 cagggaatta ggtcgtgaca aaagtaatgc gttataagaa acaagaaaaa catttgaaag
    13681 ctatttttca atacttcaga tgaatcgttc ttattacaaa acaaactttt gtatcaccgg
    13741 ttattcggaa tttgagtaaa agtgtggggt aggactgatg tcccacctcc tttttttata
    13801 aataaggaga ttgtgtatgg aaaaaaacag gaagttcaac ctcgtcgcaa ctgcggcaag
    13861 cgggctagaa gcactggttg gtaaagaatt aagagatctt ggaatcgaat gccaagttga
    13921 gaacggacgt gcacgttttg aaggaacaat ggaaacgatc gctacagcta atttatggtt
    13981 acgtacagca gatcgagtaa aaatcgtggt tggggaattc gatgcgtata cgtttgatga
    14041 attgtttgaa aacgtaaaag cattgccttg ggaagatttt cttccactag atgcagcttt
    14101 tcctgtagct ggaaaatcga tcaagtcgaa actatatagc acacctgatt gccaagcgat
    14161 cacaaaaaaa gcaatcgttg aacgtctccg tacctattat caccgtccag cttctgtacc
    14221 actgacggaa actggcgcac attttcagtt ggaagtagct ttgctgaaag accatgtgat
    14281 ggtaactctg gatacgacag gaccaagttt attcaaacgt ggttatcgct tagaaaaagg
    14341 tggagcacca ttgaaagaaa acatggcagc agcacttatt atgttgacaa attggcgaaa
    14401 agaccgtcca ttttatgatc ctgtatgtgg ttcaggtacg ctttgtattg aagcagcctt
    14461 aataggccat aatatcgcac caggattcaa tcgtgagttt gcttgcgaat cttgggattg
    14521 gttcagtcaa gaaatcatgg aaaatgttcg atcagcagcc gaagaaaaag cagattatga
    14581 tattgaatta gatattactg gttcagatat caatggacgg atgattgaaa ttgccaaagc
    14641 caatgcagaa gaaatcggat taggctcttc gattaccttt aagcaacaag cagtcaaaga
    14701 cttcaaaacg gataaagaat acggggtcat cgtggctaat ccgccttacg gagaacgtct
    14761 aggagaagaa gaaactgttc ggaaattata taaagaaatg ggcgatgtat tccgtccatt
    14821 aaaaacatgg agtaaatata tcttgactag cgacttagcg tttgaggaat tttacggaca
    14881 aaaagcaacc aaaaaaagaa aattgtacaa tggtgcattg cgtacggatc tattccagta
    14941 ttggggaact cgtccgccta gaaaaaaaga gaaagacgaa taatcttact aattgattca
    15001 ttcaattgga tgtttggagg aatagggaat gaaagaaaaa gagtttttac aagaagtaaa
    15061 agaaatcaat cttctacaac aagctttagg aatcctcgat tgggatacac aaacaggtat
    15121 gcctgaaaaa gctagtgcat accgaagtga agtagacagc tatctttaca gcatttattt
    15181 ttcaaaaaaa atcggtccaa aaatcaaaga agccattcgc tatttttctg aacatccgga
    15241 agaattgtcg gaagttggaa ctgccgtttt tgccaaagta aaagaagagt atgatttgga
    15301 acatcgcgta ccggaagatc ttatgagaaa atatacagct gccgtttctt cagcacacgg
    15361 acaatggcaa aaagctagag aaacacaaca attttctgat tttcaacacg cattgaatca
    15421 aaatattgaa ttaacaaaac agttgatacc ttactggaga aaagatgaaa agacgaatta
    15481 tgatgttttg ctgaatcaat acgaacccgg gatgactgtc gaaatccttg ataaggtatt
    15541 tgatcagctt aaagaaggaa ttctttcgat ccgccgtacg ctccaagaaa aagggactga
    15601 acctgaaaca gactttttaa atcggagaat gacgaaaaaa caacagaaga gatttgtagt
    15661 gaaagtaatc gaacaacttg gttatgattt tagtcgtggt cgtttagatg acactgtcca
    15721 cccatttatg actggaatta atccgaatga tgcacgaatc acgacacgat ggaacgaaac
    15781 agatttcaaa atggctgttt ttggagtgat ccacgaggct ggtcatggta tgtatgaaca
    15841 agacatcgat gataaatatg cgtatacacc ggtttatgaa ggtacatcaa tgggtatcca
    15901 tgaatcacaa tcgttgttta acgagatcat tattggaagt agtcgcagct tctggaaaaa
    15961 gcaatatcct ttctttcaag aatgtgcaga aggaacattc gatgatattc cttttgacaa
    16021 attttatcgt ttattgaacc atacaaaatc aagtttggtt cgtatcgagg cagacagttt
    16081 gacttaccct ctccatatca tcattcgtta tgaaatcgaa aaaatgattt tcaatgaagg
    16141 ggtagatgtt gctgaactac ctgaaatatg gaatcaaaaa tatgaagagt atctgggaat
    16201 acgaccaaca aatgatgtgg aaggcatcct acaagacgtt cattggtcag gtgcaagctt
    16261 tggttatttt ccctcttatg cattagggta catgtatgcg gcacaattac ttcattcttt
    16321 gcagcaagaa atagatgtgg aaaatgttct agcgtcagac gattattctc caatcaaaaa
    16381 ctggatgtca gagcatatcc atcaatatgg tgcatctaga aaaccaaatc aattaatcat
    16441 ggatgcaaca catgaaccgc ttaatccgca atacctgatc gactatatga aagacctgta
    16501 ttttaatgta tatcaggtaa aataaaatac aatttacaaa gatagctgaa attcatctaa
    16561 tctatagatg ttttcagcta tttacttaag aaagaagtgg aacgaatgga taaattacaa
    16621 gtgatcgctg attatagtat ggaccaatta gcgcatgatc aaacaggaca tgggagcgat
    16681 cataccaaaa gagttgtcaa gttagctgaa aaaattttgg agacggaacc gcaggcagac
    16741 cgctttgtga cgcttgcagc agcttaccta catgatacga ttgatgataa agtcgttaaa
    16801 aatgagaacg aggcaaagca acagcttcgt gtattccttc gctctttgcc aatagtagag
    16861 gaacagatct cgatgatttt ttccattatc gaaaatatgt ccttttctaa aaatctctct
    16921 gaagcggccg aactatctct ggaaggtaag atcgttcaag acgctgatcg tatcgaagca
    16981 ttaggagcaa tcggcatttt gcgtactgct tatttcggcg gtggacatgg gcacccgatt
    17041 tttgatcctg aactgtatcc gcaaacattc aaggacaaag aaaattaccg aaaaggcacg
    17101 acagtgatca atcattttta tgaaaaactg ttcttgctgt ctgataaaat gaatactgat
    17161 tacggatatg aagaagccaa acgaagagaa accttcatgc gtgaattctt agaagaattt
    17221 tttctggaat ggtctattga cgatgaaaat tttactccag acaattggat caaaaataac
    17281 aaaaaatgat ggaggttgtg acagaagtgg tcagctccaa gatatttcgg atcattttcc
    17341 gtaaaagtta cttctggaac actgtttacc aagaggtcgt gagcctgccg ttcagctccg
    17401 agtcacaagg aacaatttca aaaaatagct tctcgtgttt gatgaatatt gtaacttgtg
    17461 attcggaatt ggcaggagaa caccgtttat tcggaagaat aggactgtga caagactttt
    17521 gtcacagtcc ttttttcgaa ttcaacaagt aaaactttta agaaatattc agagagtaaa
    17581 attaaaaatt gctgataaac gaagatggaa attttatgta tttttattgg tctatgcaat
    17641 aaataaatta aatattcaga atacaattga ttttaacgaa agggcttcta tcaatggttg
    17701 tgttgtattt atctgcccag gtagagtaaa atagatcatt atctaaaagg taattgttca
    17761 tactatataa gtcatttgaa agtaaaaaga tactgtaaat aaaaaatgtg gttaaataat
    17821 tctcataatc agtgtaagcg ttatcaaaaa tatagcatac ttgctttgta gatgaatgac
    17881 acgatatatg tttggtatgt tctgcaagac agatgaatat ggaggtggag acaatgtctt
    17941 ccaaagaact aacaatgtat ttagagaaag aattggatca actgaaagaa aaggggttat
    18001 acaatacgat cgacatacta gaaagtgaaa atggtgcttg tatcatcgta gacggaaaaa
    18061 agatgatcaa tctagcatcc aacaattatc ttggatttgc caatcgcgaa gaattgaaaa
    18121 aagcatgtat tgaagcaacc gaaacttatg gtgtaggagc aggagcagtc cgaacgatca
    18181 atggttcgct gaaaatccat cagcaattag aagaaaaaat cgcagaattc aaagggacag
    18241 aagcagcaat cgcctttcaa tctggattca actgcaatat gggcgctatc tctgcagtaa
    18301 tgacaaaaga agatgctatc ttatcggatg aattaaacca tgcatctatt attgacggtt
    18361 gccgcttatc cggagcaaaa atcatccgaa ttaaacatca agatatgaaa gaccttgaga
    18421 aaaaagcaaa ggaagcgata gaaagtaaga aatataaaaa aatcatgtat atcacagatg
    18481 gtgttttctc catggatgga gacattgcac gattgccgga aattattccg attgttgaaa
    18541 aatatggact gatcacctac gtcgatgatg cgcacggctc aggcgtaact ggaaaaggtg
    18601 caggaaccgt caagcatttt ggattaagcg acaaaatcga tatgcaaatg ggcacgttat
    18661 cgaaagctat aggtgttgtt gggggttatg tagctggatc gaaaacacta atcgactggt
    18721 tgaaagctag aagtcggcca ttcctatttt ctacttcgct aactccaggt gcagctgcag
    18781 ctgcattggc ttcgattact ttgatgcaag aacatccgga acttgtcgaa aaagtttggg
    18841 aaaatgctaa ttattttaaa gaagaattga aaaaagtagg ctataacatc ggtatgtctg
    18901 aaacacctat tactccagtc attttgggag acgaaaaagt gactcagact ttctctaaga
    18961 agctgatcga acatgggatt tatgctaaac caatcgttta tccaactgtg cctcttggga
    19021 caggcaggat cagaaatatg ccgactgcgg aacatacgag ggaaatgctt gatgaagcag
    19081 tagcagttta tcaaaaaata ggaaaagaaa tggaaattat ttaactaaat ttagtttttt
    19141 cgtctattta aaattagaga acatgttcac gcatatattg ttaatcatct gaagatagta
    19201 gtaaaaaaga tcagggagga tcatcatgaa aaaagtattg gtgacaggat gtttaggaca
    19261 aattggttca gagttgatca cacggctacg tcaagaacta ggcagtgaaa atgtcattgc
    19321 gacagatata cgcatgcctg aagtcattga gaaaaacgat atctttgaga tcctagatgt
    19381 aatggattac gaaaaaatgc gcagcatagc agaacaatat caagtggaca cattgattca
    19441 tttggctgct cttttgtcag ctgttgcaga agcaaaacca caattagcct ggaatttgaa
    19501 cgtgactggg ctggtcaatg cattggaagt cgctagagaa ttccagctga aattttttac
    19561 gccaagttca atcggcgcgt ttggtccaaa tactccaaaa gatcataccc cacaagatac
    19621 tcttcagcgt cctacaacca tgtatggggt aacgaaggta gctggagaac tactatgtga
    19681 ttattattat gtgaaatatg gcgtagatac tcgtggtgtc cgtttccctg gattgatttc
    19741 ttatgcaacc ttgccaggag gcggtacgac agactacgca gtcgatattt attattcagc
    19801 aatcaaagaa ggaaagtaca ctagtttcat tgatcaaggt acatcaatgg atatgatgta
    19861 tatgccagat gcgatcgatg ccattataaa actcatgaat gcagatcctg atcgattggt
    19921 tcatcgaaat gccttcaata tatcggcgat gtcttttgac ccggaagaga tcaaagcatc
    19981 tattcaaaaa atcataccag attttgaaat ggattatgat gtggatcctg tacgtcagtc
    20041 aatagcagaa tcttggccaa attcactaga tgtttcttgt gcgcaagagg aatggggctt
    20101 ttcgccgaaa tacgacttag atgtgatgac aaaggatatg ttggaaaaac tgaaagaaaa
    20161 attggtagag acggtataaa acaagaacca catccaaaaa gttttttata cttttgggat
    20221 tggctatggt atgaaagggg acaagggatg gaagaatatc aagccacgcc agtaaaagaa
    20281 gtaaaaatag aaaatgaatt aaaacgtacg atgggatttt ttactgcttt atcgactgtt
    20341 atgggcacag tgatcggtgc aggggtattt tttaaagccg caagcgtagc agaagttaca
    20401 ggatccgcca gtttgcatat gttttcttgg tttctcggtg gtatgatttc tgtctgtgca
    20461 ggactaacag gagctgaact ggcagctgct attccagaaa caggagggat gattaaatat
    20521 atcgaacgga tttacggaaa tacagcagct tttttattgg gccgggcgca agtcgtgatt
    20581 tattttccag caaatgtagc agccttgtcg atcattttcg gtacacagtt cgtcaatcta
    20641 tttggtcttt cccagtcaat gattgttccc gtagctgtta cagctgctgt atcgatcctg
    20701 ttgatcaatt ttttaggttc taaagctgga ggggcttttc agtcgattac gcttgtctgc
    20761 aagcttattc ctttgtttgt gatcgtcatt ttcggtttgt tccgacaaga aggagtagac
    20821 ttccaactgt ttccgatcca agcaggagaa aatctttcat ttttctcagc cttgggagcg
    20881 ggcttgctag caacgatgtt cgcatacgac ggttggatac acgtaggaaa tatttcggga
    20941 gaattgaaaa agccggcgaa agatttgcca aaagcaattt ctttaggaat catcggaatc
    21001 atgatcgttt atttattagt aaatgcggtg ttcttaagaa ccgcatctat cgacggagtc
    21061 gcaggaaaca gcaatgcggc aagtgacgtt gcaaaaatga tttttggcgg cttcggtgga
    21121 agactggtca cagttggtat cttgatttct gtttatggaa ccatcaatgg ctataccctt
    21181 actggaatgc gtctccctta tgttatggca aaagaaaaca acctgccttt tagcaagctc
    21241 tttgctaaac ttcatgataa aactaaagtt cctgtagccg caggtatctt agagctagtc
    21301 atcgctattg gcatgatgat gatcggtggt tttgatacac taacggatat gctgatcttt
    21361 gtcatttgga ttttttatac gatggtcttt gttggtgtca ttcttcttcg taaaaaagaa
    21421 cctgatttgt ttcgaccata caaagttcca atgtatccgt ttattccact agtagcaatc
    21481 attggaggga cttttatcgt atcaagcacg cttatcactc agaccttttt agcttcgatg
    21541 gggatagtat tgacacttgc tggtatcccg atttatctct atttaaaacg tagatagcta
    21601 aaacattcga attttattag aactgcactt ctctgccaaa caaaatattt tatttaaatg
    21661 aggagtacgt ggaagaaatg tcaaaagtac tcgttaattt tgatcacgta aatgtcgttt
    21721 tgtctacgat gaaatagcaa agtaaaagac agaaatcggg ctcaaccgat ttctgtcttt
    21781 tactttgatt tgcgtaactg aactattcgg cgtacgccgc gataaatatt taataaaacc
    21841 aagcaaccag aaatgaaaat gggaagccaa atcagataga cagggtagcc aagcacttta
    21901 gacaaagcat gtggagtcat tttatccatt tcaagaagtg cttgctgcca agtctgaaga
    21961 ttgaagacta gcatgaaacc cgaaataatc aggagaataa atcctaaata atgaattgta
    22021 gttctttttc ttacataagc gatcgtagca taaaggaaca gtaaaaaaat aggtacgcca
    22081 aaaacaaagt acatattcag catctcgaca ccccctttgt gtttatctta ctttactttg
    22141 aaagaaatga gaaataatag cctcgttact tgcttgaaac agcaaaggac tgctaagata
    22201 agagagatac aaagaatcaa ggaggagtca tatggcaagt tatatcgaac cgattcgttt
    22261 tgcgctgatt gtttttccat ttttagcctt agcgatctca tctgtttttt ttatttatga
    22321 atatcgaaag tatggaacat ttctagtaac aagggcagtt attttgtatt ctttcgtttt
    22381 ttatttattg tgtgcgtatt ttttggtgat cttaccactt ccggcaaagg agacggttgc
    22441 ccaaatgaca gggccaaaga tggagctgca tttatttgct tcatggcaac atttcagaga
    22501 caacacggta ttggtcttgt ctgaacctag tacctacctg ccggcaatga agcagagtgt
    22561 atttttggaa ccagctttta atgttttatt actcatacca tttggcattt atttaagata
    22621 ttatttccgg ctttctttta tgaaaacgat gattgctagt ttctgccttt ctctattttt
    22681 tgaattgacg cagctaagtg gactttattt tatctaccca agaccatacc gcttatttga
    22741 tgtgaatgat ttagtgacaa atacattggg tggaatcatt ggttttgtcg ttacgccgtt
    22801 atttacattt atgcttccta caagaagacg aatggatgaa ctttcttatg aaaaaggaaa
    22861 gactgtctca ttgactcgac gcttggtcgc ttatttgatc gactggacat ttttatctct
    22921 tattaatttg gtagcggcga ttttctttaa aattgcgttc gattcagggg cagttacttc
    22981 tcatatctgg tggcttttat tagaagtagg ggtatacttt atgattgtac cgtttataac
    23041 caatggatgg acacttggca aaaaaattgt gcgtatccgt ttggtggaag aagaccgcga
    23101 acgaatttct ttaaaagcat tgatgatccg ctacgggtat ctgtactttc ttttttatgg
    23161 tttaagctgg ttggggcagt tgcttcagca aatcatgaat tcgacaacga atacggtgtt
    23221 gcagatgagt gcagtattca tttctctcgg tgtcttgtta ctacaaggta tttttatttt
    23281 aaatatcttg ctatcatttt tgagaaaaaa acggattctg ttttatgaaa aagctagtca
    23341 cacatatact gttagcacga ttggccaaac aaaggatgat gattctcgaa attagctgag
    23401 caaaaacgct ttgtctgtgt tataatgcca aagtcgtgat aatttaaaga gaagaggtgc
    23461 acgaatgaat aattttgata tattccgctt caaaccgttt atcaatgaag cgttaaccgc
    23521 aaagggcttc aaacagccca cagaggtcca ggaacgtttg attcctttaa ttgcaaaagg
    23581 aaaaaatatc attgggcaat ctcaaactgg tacaggaaaa acacatacgt ttttgttgcc
    23641 tttgtttgaa aaaatcaatg cagaaaaaga ggaagtacaa gttgttatta cagctccaag
    23701 tagggaacta gctgcacaga tctatgaagc agctacacaa atcgctaaat tttctacacc
    23761 ggagatccgt gtctcgaatt ttgtcggcgg tacagacaaa cagcgtcaat taaatcgtct
    23821 gcatcaccaa cagccacagg ttgtagtagg cacgcctggt agaatattag acatgatgaa
    23881 tgaacaagcg ctgaagattc acaccgcatt tgcatttgtt gtcgatgaag cggatatgac
    23941 attggatatg ggttttttaa atgaagtaga ccaaattgca agtcgattac cagaaaagct
    24001 gcagttttta gttttttctg ccactattcc agaaaaactt cgtccattct tacgaaaata
    24061 catggaaaat ccaatcattg aagaaatcaa accaaaagca gttatttctg aagacattga
    24121 aaattggctg atttcaacaa aaggtaaaga tgagaatcaa atgatttatc aactgctgac
    24181 aattggtcat ccttatttag caatcgtatt tgccaataca aaacagcatg tggatgaaat
    24241 tgccgattac ttgaaaaacc aaggcttgaa agtagcaaag attcatggag acatcacccc
    24301 aagagagaga aaacgagtga tgcgacaagt acagaatctg gagtatcaat atgttgtagc
    24361 gactgattta gctgctagag ggatcgatat cgaaggtgtc tctcatgtta ttaatgcaga
    24421 aattccagaa gatctagact tctttatcca tcgtgtcgga cgtactggac gtaatggctt
    24481 aaaaggaacg gccattacgt tatattcgcc aaatgatgag caagccattg atgcgataga
    24541 aaaattgggc gtctcatttg aaccaaaaga aatcaaaaac ggggaaatcg tcaaaacata
    24601 cgatcgtaat agacgtgcca aacgagaaaa atcaaaagat gtattagatc ccacgctgat
    24661 tggtcttgtg aagaagaaaa agaaaaagat caagcctggt tataagaaaa aaatcgattg
    24721 ggcaattgca gaaaaaaata aaaaagaacg caaaatcgaa cgcagacagc aaagccgtac
    24781 tgctcgtaaa aataagaaaa attcacataa ataaaaaaca agaggttgtg acaaaaggcg
    24841 tgtcacaatc tcttgttttt aagctagact ttttttcatt ccgatacaaa gtacttcatc
    24901 ttcaataaaa ggttctgtgc aagtatgata cccttgtttt tcataaaaat ctacagccgt
    24961 catttcagct actacataac tagtctgaca accttctgaa accgcccgtt tttcagcagc
    25021 ttcaagcaac tgaccgccta acccttttcc tcggtattct tttgctacgc aaaatcgttc
    25081 cggcttgaag caagtaggtg ttttcttttc ataacgcaaa gtagctactg gtcttttttg
    25141 atcaagaaat agataatagg tttgttgcgg gatatctttt ccgtcgaatt ctagttctgc
    25201 aggaatccct tgttctaata caaaaattga tatctcaaaa agcagctagc tgcgcgtatc
    25261 cattcatccg ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat
    25321 gtattgattc ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga
    25381 aaataaaaat tgagatattg acagtgatca atagaatgcg tatactaatt aagtacgaaa
    25441 aggatatgat ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag
    25501 tcactaatca aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt
    25561 atcgagttta agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc
    25621 gtccttggct gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga
    25681 aacaattaag tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaaggac
    25741 atacgattga acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca
    25801 actctggtgt tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa
    25861 gaatcacaaa tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag
    25921 cacggcacca tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa
    25981 atgaagccat ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc
    26041 cagaaaaact ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg
    26101 aagaagttgg cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg
    26161 gtgcaggccc atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg
    26221 atttagcaga agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa
    26281 tctggaactt agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc
    26341 ctcataaaaa cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg
    26401 cgtcaacgaa ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa
    26461 gcaaacaagt aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag
    26521 atcatattcg cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga
    26581 gagggtatgt cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta
    26641 ttgaacaagc attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt
    26701 atcctgaagt acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac
    26761 gtttcaatga aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa
    26821 aaaacgaaaa cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg
    26881 gcttcccggt agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg
    26941 ctggttttga aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg
    27001 aaaaatcaat gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca
    27061 ttggatacac agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc
    27121 ttttgaatga agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg
    27181 cagaaatggg tgggcaagta gcggatcaag gatggatcat gaatgaagta ggcgaaatcg
    27241 tagcagttgt tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag
    27301 taaaagcacc aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca
    27361 atcggatcat caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac
    27421 ttggcgagca tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact
    27481 ttacccactt tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg
    27541 aaaaaatctg ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa
    27601 acatgggtgc aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata
    27661 ttggcggctg gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg
    27721 gaatcttcaa aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg
    27781 taacaagtaa agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag
    27841 caacaattgt taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac
    27901 agcaagtaag agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac
    27961 aagctggtga tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac
    28021 aagtaaaagt gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa
    28081 atatttcaga tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg
    28141 caatgacgaa agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg
    28201 caccgaaagt aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa
    28261 atcctgctgg tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg
    28321 gcgtttacgt ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg
    28381 cgaagacaaa caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat
    28441 ggtcggattc ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa
    28501 ataaaaaggg gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg
    28561 atcttgttag caatcatcat cgtacaagcg atggttcctt ggctggggtt tattccatta
    28621 ggattcatta gtttaacaat tatccatatc acagtaatta ttgctgcagt agtattaggc
    28681 ccaaaagatg gcatggtgat tggcttgttt tggggaatcg ctacaattgt tcgtgcctat
    28741 gccatgccaa caacgccatt tgatacatta gtgttcacga atccgattat ctcggtagtt
    28801 cccagagtac ttgttggctt agtagcaggc ttggttttcc actggattta tcaaaaaaat
    28861 aaatcaataa cgatcagctc agcctttgca ggggtactgg gttcattggt caatacagtc
    28921 ttagtgttag gattcatggg attattttat acaggtgcaa cggcagatgc ctatggtgta
    28981 gactctgctc ttttatttaa aaccttagca ggggttgcag caatcaatgg gataccagaa
    29041 gcaataggtg cgggaatcat aacaccatta ctagcaaaag cgttatttgc agcaacaccg
    29101 ttgaaaccag aataatgacc atcttttaat agtaatagga cgcacgatag atagaaaaag
    29161 gaagagagga gaggaaaaca atcgtcctct ccatcttttt acctgagcaa caagcaaact
    29221 agaaggggta aaaaacttgg ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca
    29281 gcggacaaaa aaaggagtac tagcgggtat cttaggattg gttacgaatc tgatcttgtt
    29341 tgtctctaag ctaatgatcg ggcttttttc aggaagtgtc tccattatgg ctgatgcagt
    29401 gaacagtcta tcagatactg cttcatccat attgactttg atcggattta aaattgctgc
    29461 aaagccagca gatcaggaac atccttatgg acacgaacgc ttcgaatata tcagtgggtt
    29521 atttgtttcg atcatcatta cttatgtagg atttcaattt ttagagtctt ctgctgaaaa
    29581 aatcatccat ccagaaaatg tctctttaac acccatcgtc ttttttgtcc taatcatttc
    29641 catctttttg aaatttgcac aaggcaaaat gtatcaggtt attgcgcaat ccattgattc
    29701 tgaaacattg agagctacag caacagatag ttataatgat gtctttacta cactggctgt
    29761 attgctttca gcagcaatcg aatgggtaac tggatggcgt attgatggat atataggttt
    29821 tgctttagca ttatatatcc tttatagtgg attgacgatg cttcgaaatt ttgtatacga
    29881 actattagga agtcgcccaa cgccagcaga gattgaagaa atggaagagc atttaaatgc
    29941 ttgcgatgat atacttggct atcatgattt attggtgcat aactatggac ccaataaacg
    30001 ctttgcatca gtccacatcg aagtagatga atcaatgaat ttgaatgtgg ctcataagat
    30061 tattgatctg atagaaaaag actttaaaaa gtctttggat gtggaacttg tctgtcactt
    30121 ggatccaatg cctgttgata acgaaaaata ctataatatc ttgcggcagt taaagcaaat
    30181 tcttcttgaa acaggtacag ggcttaatat tcatgatttt agagtaattc atcaaggaaa
    30241 aacgctgcaa tttgatgtag tggtccctga gaaattccag tttgttgata cagaactaga
    30301 aagaatctta cgtagtcaaa tagaagaaaa aatcggagat taccaattgg aaattacgtt
    30361 tgatcacaat tatcttttat attaaatgag aaactataaa aagactcctt aaagttttta
    30421 atttaaagag tctttttttc ttttaattgt ttatggagag cctgacgtgc aagattatct
    30481 gctcctttat ttttgttttc gggcaaccat tgcaggatca ataaagaaaa ttcggataga
    30541 agttcttgga ttctttgaag gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg
    30601 accgtagaaa ctagtgtttt gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg
    30661 tttttcttta gaaattctaa agtttttaaa aagacttcga actctgcttg atggtttgtc
    30721 cctatagaaa gcgggataga tagctgttct tgtttacctt gatagacaat caagattcca
    30781 cctccactag gaccagggtt gccttttgta gaggcatcaa tgtatacttt taacataaaa
    30841 agagattctc ctttttgttc aaactaatgt tatggtaaga ttatatcatt actgaatcgg
    30901 tgagaggtta gagaatgaaa aaaaatattc gatggcagcc tgaactggca catacgatca
    30961 tctattggtc attgaccttg atcattctgt tttttagtct gattctttct ttagaaaaca
    31021 caggtcctta ttggaaaagc aattttgttt taggtatttt tcttgttttt ctatttctag
    31081 gtttgcggcg ttcttttatt ttaaaatcaa actctgtgat tatacgttat gctgcttttt
    31141 ggaaagaccg agaaatatct gtcggacaga ttcgatcttt gacgccaact aatactgggg
    31201 tgcaaatgat gttgcaagat gagaaagccc catctgtttt catgatgcga aaaaaagatc
    31261 aagtagtcct ttttgatcat tttgaaaaaa acggacccaa atcagaatca attccttatc
    31321 cttatacgaa aaaaagaaaa agctaatttt aaaaatcaga acctaaaaaa acgaattttt
    31381 acaggaaaag aaaagagtga gacgtacggt tcatcccgtt tagcgtctca ctctatttgt
    31441 ttatctattc atgcatacta gtatcggtag tctgaacgtt gcctttcttg acatgggcag
    31501 cttgtgttcc tcgattccct tcgatgatct caaattcgac cacttgattt tcttccaaag
    31561 ttttgaatcc ctcttcttca atcgcagtaa aatgtacaaa aatttcttct gtgtcatcat
    31621 aactgataaa gccgtatcct tttttgttgt caaaccattt tacaattcct gtggtcaaag
    31681 cactcacgac ctttctaaag tctgatcata gccttcatta taaagagtat ttataagtac
    31741 gtcaaataaa ttaaaaacct gtaattttat gttttttttc tgaataaaaa aaggtataat
    31801 tggcatatct taacaaagaa gatattttgt tgaataaagt tcgtgaaaag gggtaatcaa
    31861 atgaagaatg atctgcaaat ttcacaagaa acagagctag aaccgattgt tgaagtggct
    31921 agtaaattag atcttaagga agacgatttg gaactgtatg ggaaatataa ggcgaaaatc
    31981 aatttttctg gaatcaatcg atcaaaggat aacgctgagg ggcatttgat cttagttact
    32041 tccatcaatc caacaccagc tggcgaagga aagtcaacga tcactgtagg gttaggagac
    32101 gcgctcaata aaatcaataa aaaatctgtt attgcattgc gagaaccctc acttggtcct
    32161 gtgatgggaa tcaaaggtgg tgctgcaggc ggaggatatg cacaggtatt gcctatggaa
    32221 gatatcaact tgcattttac tggtgacatg catgctatca caacagctaa taatgcatta
    32281 tctgctcttt tagataatca tattcatcaa ggaaatgaat tgaacatcga tgcccgccga
    32341 gtgatttgga aacgggtagt cgatctcaat gatcgtgaac tgcgtaaagt aattgttggc
    32401 ttgggtgggc caatccaagg tgttccaaga gaagatgggt ttgatatcac agttgccagc
    32461 gaaatcatgg ctatcttgtg tcttgcggca gaccttgaag atttaaaggc tcgtcttgca
    32521 aggatcgttg tcggctatac atttgaccgt cagcctgtga ctgctggaga cttgaaagca
    32581 gaaggcgctc tggcattact gctgaaagat gcaatcaagc cgaatcttgt acaaacaatt
    32641 tacggaacac cagcttttgt ccacggggga ccgtttgcca atatcgctca tggctgcaat
    32701 agtattttag ctaccaagac agcattgaga ttagcagatt acgttgtcac agaggcagga
    32761 tttggtgcag atcttggcgg agagaaattt ttagatatca aagtacctaa cttgaaaaaa
    32821 gcgccggatg ctgtggtgat tgtcgccact gtccgtgcat tgaaaatgca tggcggaatg
    32881 aaaaaagatg aacttaaaaa tgagaatctt gatgctttga aagtaggttt tgcaaattta
    32941 aagcgccata tacgtaatat ggaacaatat cagctacctg tgatcgtcgc aatcaatgaa
    33001 ttcgtaacag atacagacaa tgaactcaca ctgttggagc acttgtgtga aaatcagggg
    33061 attcttgcca agagagcgag tgtatgggca gatggagcag aaggcggcgt tgatttagca
    33121 aaagctgtag tacgattgat tgatagaaaa gaagctaatt acaagccatt ataccgccta
    33181 gaagaaacga tacaagaaaa gacagaaaca atcgtcaaga aaatttacgg aggaaatggt
    33241 gttgttttca gcaaaaaagc gcaaaaacaa atagaagagt ttacgaagaa tggatgggac
    33301 aaactgccga tttgtatggc aaaaacacag tattcatttt ctgatgatcc ttcactgcta
    33361 ggtgcaccgg aagatttcac catcacgatc cgcgaaatca tcccaaaatt aggggcagga
    33421 tttttagtag ccttgactgg agatgttatg acgatgcctg gtttgcctaa aaaacctgct
    33481 gcattgaata tggacgtgac aaatgacgga gaagtgttgg gattgtttta agcttgatta
    33541 taatctacca tcgaaggagc tgtattttga ctacagcttc tttttttaga cgatagggaa
    33601 ttaattttgt ttacactagg atcattcttt ttctttattg tattttgagc tatactaaag
    33661 cataatagga gggtatgatg aaaacgacat ttataagaaa aaccggtttt tacggtatgg
    33721 gtagctcgat tcagctaaga atcaacaatg aaaaacgcag tgttctcagt catgaacaaa
    33781 agataacgct tgatctggaa gtgcccttta cgatgcaggt caccttttat tggctaaaaa
    33841 gccccgttta tacagtgaaa gaagcaaagc ctgcttatgt gatcacaatg aattacttga
    33901 ttcttcaaat ctatccgttt ttatttctag caactgggtt gggggccgtt ttcctacaaa
    33961 atttattttt cagttttttt gcagttattg tgttgattgc gttctttttc tatataaaaa
    34021 accgggcata tttgatcaag gaggaaaatt atggcaaact ctgatctttt tttaatcagt
    34081 ttcaatcgaa tcgaaaaatg gatgagagac gagatgggaa atgcacgaaa tatgggattt
    34141 accgaacttg tcagacgcct agctcaaaga aaacaattaa tgatcagaaa atacgaagat
    34201 gatcttttac agcttgctca gttaaggaat gcgatcgtcc atgatcggat cgcagtcgat
    34261 tttgtcattg cagagccaaa tgattggaca gtcaagcgaa tccagctgat cgaacaagaa
    34321 ctgattcagc ctgaaaccgt gctgcctcga tttgcaaaac gtgtaacagg ttttgaacaa
    34381 gatcttccgt tacttgaact gttaaagata gtagcagaaa aaaggtattc acaatttccg
    34441 ttatacaata aaggaaaatt tgtagcattg attactttac gtaatatcgg gttttggcta
    34501 gcaaaagaaa gccaaaaagg tccggttgat ttaacaaata aacgagcgtt ggatttgatc
    34561 atccaaaacg gaaagtacac aaattatcat tttgttccag ctaaaacaca tatttacgag
    34621 gttgaagcga tgtttcgtga gcaagggact ttggaagccg tacttatcac taaagatggg
    34681 aatcccgatg gtaatctgct cgggatcgta cgacctcgtg atatttataa acaaatagaa
    34741 aaggattgat tttttgttaa ttatttattg gatattcagc gctttgctag taggagtgga
    34801 tcagttggtc aaatggtgga tcactgataa tctagcgctt ggagagacga aaaatcttat
    34861 accaggtatt ttgtcactga atcatattcg aaacactgga gccgcatgga gtatgctaga
    34921 agggaagatg tggttcttta ctatagtgac actcattgca gtcgttgtga ttctcacatt
    34981 gatgattaaa aatcgtgaaa aaggtaatcg ctggttcatg attggattga gtttgattct
    35041 agctggtgcg attggcaatt ttatcgaccg tattcgtctt ggctatgtag tagatatgtt
    35101 ccagacagat tttatgagct ttccgatttt taacgtagca gatgtgacac ttgtatgtgg
    35161 agtgatttgt atgttaattt atattatttt agatgaaaag gatcaaagaa aaaaatgaca
    35221 gaacttaaaa cgacgattca ccatgaatct ggtaggatcg ataaagtatt gactaattta
    35281 ttcaccgatt acagtcgttc gcaaattcag ctgtggctga aaaatggagc ggtttctgtc
    35341 aatggacagc cagtcaaagc aaattacaaa gtaaaacaag gagacgagat tactgtcttg
    35401 atccccgaac cagaaacatt agatgtggtc ccagaaaata tcccgttgac gatcgtttac
    35461 gaagatgaag atgtagcggt gataaacaaa cctcaaggaa tggtcgttca tccttcagca
    35521 ggtcatacgc atggcacaat ggtcaatgcg ctgatgtacc atatcaagga tctttctacg
    35581 atcaacggcg ttattcgtcc aggtattgtt caccgaatcg acaaagatac ttccggactg
    35641 ctaatggttg ccaaaaatga ccaggcacac gaatcattag ctcagcaatt aaaagataag
    35701 acctctttgc gcaaatatgt tgctttagtc catggagaga ttcctcacga aaaaggaacc
    35761 atcaatgcgc caatcggccg ttcgaaggaa aaccggaaaa tgcaggcgat aagagaagat
    35821 gggaagtcgg ctgtcacaca ttttactgta ttggaacgtt tcgaaggatt tactctggtt
    35881 gaattaaaac tagaaaccgg aagaacacac cagatccgtg tgcatatgaa gtatatcggt
    35941 tatccgttag ctggagatcc agtatacgga ccgaagaaaa ctttgaaagg caatggtcag
    36001 tttctccatg cgcaaatgtt aggttttacg cacccgacta caaacgaaaa gatgatcttt
    36061 gaagcacctc ttccagaagt ttttgaaaaa actttagaaa aattaagaaa aaacattgca
    36121 ttttaattta gataacggta tagtaattaa caacgaaagc ataaaactta atagaattcc
    36181 tttaagttta gtcccgtgag gctaagaagg gtgggagcaa ggatacgtat ggtgcgccat
    36241 aagtagattg ctcattgaca tagtatagct atcagtgtat cagtatacgc tcagtctaaa
    36301 cattcctcct gtcctcttag ggcaggagtt tttttatgca aaaaagtagg gggaatgaaa
    36361 atgcaagcaa aagaagtagt agatcaggta accatgaagc gagcattgac tcgaattact
    36421 tatgagatta tcgagagaaa ccatagtatc caagatatcg tattggtagg tatcaaaaca
    36481 cgaggaatct acattgcatc aagaattgcc gaacgcctga agcagctaga agatatcgat
    36541 attcctgtag gagaactgga tatcacttta taccgagatg acaaaaaaga aaatccagaa
    36601 gaaccggaac ttcattcttc tgacatccca gtttccttag aaggaaaaga agttattttg
    36661 attgatgatg ttttgtatac aggacgaacg attcgagcag caatggacgc agtaatggat
    36721 tttggcagac caagaaaaat ttcattagca gtcctggtcg atcgtgggca tcgagaattg
    36781 ccaatccgtg cagattatgt tgggaagaac attccaacat ctcgggcgga agagatttta
    36841 gtagagatgc aagagcttga tggacaagat cgcatcatga ttttgaaaga ggaagattag
    36901 aggagagaga aacatgtcgg agaaaaaagg atttcataat gatgacgtgg tgttagatat
    36961 ccacgatcgc ccaaccccag gacattgggt aggattaagt ttacaacact tgttcacgat
    37021 gttcggagca accgtgttag tccccatctt agtaggtatc gatccaggta ttgcgctagt
    37081 cagttcagga ctaggtacat tggtgtactt atttactact aaaggaaaga tacctgcgta
    37141 cttaggaagc agcttcgctt tcattgcagc gatgcagctt ttgatgaaaa cagatggtta
    37201 tccagcgatt gcacaaggag cagtcacaac tggattagtc tatttgattg ttgcgctgat
    37261 catcaaaaag atcggttcag catggctgga taaaatcttg cctccaatcg tcgtcggtcc
    37321 agtcatcatg gttatcgggt tgggacttgc ggcaaatgca gcaacaaatg ctatgtataa
    37381 tcagggcacg tatgatttca agtatattgc tgtagcgctg atcacattag gattaacaat
    37441 tttcttcaac atgtggctaa gaggttttct cggattgatt ccgattttac taggtattat
    37501 tagcggatac atcgtagcct tgctgtttgg aatcgtggat actaagccaa tcgtagacgc
    37561 tgcctggttt gctgttccta actttgagat tccctttgta caatatgaac caaagctata
    37621 tcttggagca atcacaacaa tggcacccat cgcttttgtg acgatgacag agcatatcgg
    37681 ccatcttatg gtattgaata aactaactaa acgtaatttc tttgaagaac cgggtcttca
    37741 taagacgttg acaggtgatg gattagcaca aatcgtggca gcctttgtcg gaggtcctcc
    37801 tgtaacaagt tacggtgaaa acattggtgt tctggctatc acacgtgtcc atagcgtgtt
    37861 tgtgatcggt ggagctgcag tatttgcagt cattttagga ttcgtaggaa aattaagcgc
    37921 tttgatttta agtatccctg gaccagtcat ctcaggaatc agttttatct tatttggagt
    37981 aattgccgca agtggaatga agattttaat cgagaacaaa atcgattttg ataaaaagaa
    38041 aaatctgttg attgcttcag ttatcttagt agtaggaatt ggcggactcg tctttgaagt
    38101 aggcacattt acattgtcgg caatggcatt agcaactgta cttggcatca ttttaaatct
    38161 tatcttacca gaaacttcac gaagcgaaga aaactaagga ggaaacatta tgatcatcaa
    38221 atcagaacgt atcagcttaa agcatttatt gaccgttgag gcacttactg atcaagaagt
    38281 tatgggcttg atccgcagag ggcaggaatt caagcaaggt gctaattgga ctccgcaaaa
    38341 gcgccagtac tttgctacaa acctcttttt cgaaaatagt actcgcacac ataaaagctt
    38401 cgatgtagcg gagaaaaaac tagggctaga agtgattgaa tttgaagcaa gcacaagctc
    38461 tgtccaaaaa ggggaaacac tatacgatac agtactgacg atgtcagcat taggcgtaga
    38521 cgtagcggtt atccgtcatg gtgatgagaa ctattatgac gaactgatac aaagtaaaac
    38581 aatccagtgt tcgattatca atggaggaga cggaagcgga cagcatccaa cccaatgctt
    38641 gcttgatttg atgaccattt atgaagaatt tggtcatttt gaaggtctga aagttgccat
    38701 cgtaggtgat atcactcact ctcgcgtagc taaatccaat atgcagatgt taaaacgtct
    38761 aggcgcacaa gtattcttct caggtcctag agaatggtac gacgatgaat tcgaagtgta
    38821 cggacattat atgccattgg atgaactact agatcaagtt gatgtcatga tgatgcttcg
    38881 ggtgcaacac gaacgccatg atggaaaaga aagtttctca aaagaaggct accatcagga
    38941 acatgggtta acagttgagc gtgcgaagaa gttgcaaaaa catgcaatca ttatgcaccc
    39001 agcaccagtt aaccgtgatg tagaattagc tgattcatta gtggaaggat tacagtcgcg
    39061 gatcgttcag caaatgagca atggagtatt cgtcagaatg gcaatcttag aagcagtgct
    39121 aaatggaaaa gcgtaattat aggaggatga aaaaatgaaa acactcatta aaaacggtca
    39181 gatcaataca cgaaaaaata tgacgacacc agcagaaatt tggatagaag atgggcgaat
    39241 caaagcaatc ggtacaggat tctcagaagc cgaatttgat gaagtgtttg atgcaaaggg
    39301 acaattgatc acacctggtt tagtggacgt ccatgttcat ttgagagagc caggatttac
    39361 atacaaggag acgatcgaag ctgggactcg ctcagctgct cgtggcggtt tcactactgt
    39421 atgcgcgatg ccgaatttaa atcctgtacc tgatacggca gaaaagctga gacaagtata
    39481 tgacatcatt agaaaagatg cagttgtgaa ggtattgcag tatgcgccaa tcacagaaaa
    39541 tctgcgaagt gagaaattag ttgatcaaga agcactgatt gaagaaggtg cttttgcttt
    39601 cacaaatgac ggtgtaggtg tccaaacagc tgggacgatg tatctggcta tgaaagaagc
    39661 tgcaaaaaac aataaagccc tagtagccca tacagaagat gaatctttat tatttggcgg
    39721 cgttatgcac gctggcaaga aggcagaaga acttggtctt cccgggatct taagcgtaac
    39781 cgagtcttct caaattgcta gagatctgtt gctagctgaa gcaactggtg ttcattacca
    39841 tgtttgccat gtttctacta aagaaagtgt ccgtgtaatc agagacgcaa aaaaagcagg
    39901 aatccacgta acagcagaag tttcacccca tcatcttatt ttgatcgacg aagatattcc
    39961 cgaagatttc ggcttttgga aaatgaaccc gccgctaaga ggacgggagg acagagaagc
    40021 tttgatcgaa ggcttgcttg acggtacgat cgattgcatc gctacagacc atgcccccca
    40081 tggattagaa gaaaaaagcc aaagtttcat gaaatcacca tttggtatcg taggaagcga
    40141 aacagcgttt caactgatct atactcattt tgtagaaact ggtcgattca cgttggaaca
    40201 agtgatcaat tggttggcag ttaaaccggc tgagattttt ggtttgaatg caggaacgct
    40261 aacggttggt gcccccgctg atgtagcagt ttttgatatt acacaaactt gcacgatcga
    40321 taaagaagac tttttatcaa aaggggagaa tacacctttt atcggctgga aagtaaaagg
    40381 cgaaacacaa atgacttttg tcaacggaaa acttgtgtgg cagaagggag aataaaagta
    40441 tggaacgttt gcttatatta gaagatggaa cagttttcga aggaaaggct tttggtgcag
    40501 atgctagtgt cttcggagaa atcgttttta caacaagtat gactggttat caagaaacta
    40561 tcactgatca aagttttaac ggtcaaatca ttacatttac ctatcctatg gtgggtaatt
    40621 atggggtaaa tagagatgat tatgaatcga tttctccaac atgcaaagga gtagtagtaa
    40681 aagaacatgc acgtgtagct tcaaactggc gaaaccaaat gacgctagat tcatttttga
    40741 aacaaaaagg aattcctgga atatcaggta tcgatacgcg cgcccttact cgcaaaatcc
    40801 gtgaagtcgg aacgatgaaa gctagtatag ttgatgctgg agattccttc gaacatgcat
    40861 ttgatcagct gaaagcaacc gttctagcaa ccaatcaagt gcagcaagtc tcaactaaca
    40921 aaccttatcc aagtccagga acaggtcgga aagtcattgt cattgacttc ggcttgaaac
    40981 atagtatttt acgagaattg agtaaaagaa actgtaacct cacagtactt ccctataaca
    41041 cagatgccga gacgatttta gcgctatcac cagacggagt catgctgacg aatggacctg
    41101 gtgatccaaa agatgtgcca gaagcaatcg aaatgatcaa aaaaatccaa ggaaaagtac
    41161 cgatttttgg tatttgtctc ggtcaccagt tatttgcttt agccaacggt gcagatacct
    41221 ataaaatgaa attcggacat cgaggattaa atcacccggt acgagaagta gcgaccggaa
    41281 gaattgattt tacttctcaa aatcatggct atgcagtcga tgaagccacg attgatccag
    41341 aaaaactcat cgtaactcat gtagaagtaa atgacggaac agtagaagga gtcaaacaca
    41401 gagattatcc cgctttcagt gtgcagtttc atccagatgc tgcccctggt ccgcatgatg
    41461 cactacattt atttgatgaa tttatggaaa tgatggacgc aggaaaggag cagtaaacag
    41521 atgccgaaac gtacagatat caagaaaatt atggtgattg gatctggtcc gatcatcatt
    41581 ggtcaagccg cagaatttga ctacgcagga acacaagcct gccttgcctt aaaagaagaa
    41641 ggatatgaag tggttttagt aaattctaat cctgcgacga tcatgacgga taaagaagtg
    41701 gcagatcaag tatatatcga accgatcaca cttgaatttg tatcaaggat tcttcgaaaa
    41761 gagcgtccag atgctctcct tccaacttta ggcggacaga caggcctcaa tatggcaatg
    41821 gagctggcag catcaggtat tttagaagaa ttgaacatag aacttctagg aacaaagctt
    41881 tctgcgatcg atcaagcaga agatcgtgat ctattcaaac agttgatgaa agaattgaat
    41941 cagccaatcc ccgagtctga aatcgtcaat acagtagaag aagctgtaga ttttgcaaat
    42001 aaaatcggct atcctgtcat cgttcgtcca gcctttactt taggcggaac tggtggaggt
    42061 atgtgtgaaa atgaagaaga attacgtatc gtatcagaaa atggattaag tctttccccc
    42121 gctacccaat gtttgattga acgaagtatt gcaggtttta aagaaattga atatgaagtg
    42181 atgagagatt cggctgataa tgcaatcgtt gtctgcaata tggaaaattt tgacccggtg
    42241 ggtatccata caggtgattc tatcgtattt gcccctagtc aaacattgtc tgaccatgaa
    42301 tatcaaatgc ttcgtgatgc ttctctttcg attattcgag cacttaagat cgagggaggc
    42361 tgtaatgtcc aactcgctct tgatccacat agttttaatt attatgtgat tgaagtcaat
    42421 ccgcgtgttt ctcgttcatc tgcgttagca agtaaggcga ctggctatcc gatcgctaag
    42481 ctagctgcta aaatagcgct tggattaaca ttagacgaaa tgaaaaatcc tgttacagga
    42541 acgacttttg cagaatttga acctgcatta gattatgttg tagctaaaat tcctcgctgg
    42601 ccgtttgata agtttgaaaa cggagaacgg cttttaggca cgcagatgaa agcaactggt
    42661 gaagtgatgg ctatcggtcg gaatatcgaa gagtctttat tgaaagctgt gcgttcttta
    42721 gaaatcggta cacaccatat cgaacttcct gagttggcag acatcacgga cgatgaccta
    42781 atccaaaaag tggttcgagc acaagatgat cgcctgtttt atgtagctga agctattaga
    42841 agagggtaca ccatagaaga attagcggat ttgacaaaaa tcgatttatt ctttttagat
    42901 aaactgttgc atatcgtaga aatcgaacag cagttgaaac agcagccgtt ggatgacaag
    42961 atattgaaaa cagcgaaaca aaacggtttt acagacaaaa aagtggcgga gctgtgggaa
    43021 ataaacgaag aagccgttcg ccagatgaga aaagaaaatg atttgattcc tgtatataag
    43081 atggttgaca cttgtgcagc ggaattcgaa tcaaaaacac cttattttta tagttcctat
    43141 gaatatgaaa atgaaagttc acgatcagaa aagccctcaa ttctagtact gggatctggt
    43201 cctatccgta tcggacaagg ggttgaattt gactatgcga ctgtgcattc tgtcaaagca
    43261 atccagcagg caggatacga agcaatcatc atgaacagca atcctgaaac agtttcgact
    43321 gacttttcta tttcggataa attatatttt gagccattga ccttcgaaga tgtgatgaat
    43381 gtgatcgagc tagaacagcc gataggagta atcgttcaat ttggtggtca gacagcaatc
    43441 aacttagccg aacctttgac tgctgctggt gtaaaaatct tagggacaac gatcgaagac
    43501 ttggatcgtg cggaaaatcg tgatttattc gagcaagcgc tgaaagagtt ggatattcct
    43561 caacctttag gggatactgc tacaagtaaa gaagaagccg tggttatcgc ttcgagaatt
    43621 ggttatccag ttcttgttcg tccaagctat gtattaggcg gacgtgcgat ggaaatcgtt
    43681 gaaaaccagc gagatttaga agattacatg gaacatgctg tgaaagcatc tccagaacat
    43741 ccagtactag tggaccgtta cttgcttggt ggtgaatgcg aagtggatgc gatttgtgac
    43801 ggtgaaacag tactcatccc agggatcatg gagcatattg agcgtgctgg tgtccattca
    43861 ggggattcaa tggctgtgta tccacctcaa acattatctg aatcgatcaa gaaaacgatc
    43921 gaagattaca cgatccgctt agcattaggt ttgaattgtg tcgggatgat gaatatccag
    43981 tttgtcatcc atgaaaatga ggtttatgtg atcgaagtca atcctcgagc aagtcggact
    44041 gttccattct taagtaaggt gacaggaatt ccaatggcac aaattgcgac gaaagctatt
    44101 ttgggagaga aactaaagac acttggttat gaaaacggac tttatccaga aacaaaagaa
    44161 gttcatgtta aagcacctgt cttttctttt acgaaattgc agaaagttga tacttactta
    44221 gggcctgaaa tgaaatcgac tggagaagta atgggatctg acagacaatt agacaaagct
    44281 ttgtacaagg cattcgaagc ttctggatta cacttgcctg aatatggagc cgtattattt
    44341 acgattgcgg acgaaacaaa agaagaagca ctagaattag ctaaacgttt tacagaaatt
    44401 ggctatagtc tgataggaac gaaacataca gctgcttatt tcgaaaaaaa tggtctggtc
    44461 gttgaaacag tagcgaaaat ttctgaggaa gcagcagaaa aaaatgtagt cgacttaata
    44521 agagatggta aaacacaagt ggttgtcaat acgattgata aagatcgggg aaatgcttct
    44581 aaagacggtt tcatcatccg aagagaagca gttgaacatg gtattccatt gtttacttct
    44641 ttagacacag cagatgcgat cgttcgagtg atggaatccc gtgctttttc aactaaccct
    44701 atttaacggc gagcacatgt taagacaaaa agacgaaaaa ccgttgcagg aggggacaga
    44761 tgaaacaaga aatgatggaa atcgttcagc aaaaacagct ggcaccaaag atttttgaaa
    44821 tgacattgaa aggtgatcta gtaaaagaaa tgcagcaacc aggacagttc ttgcatattc
    44881 tcgtgccgcg tgcagacttg ctattacgcc gaccgattag cttgaatcat atcgaccacg
    44941 aaacaaatac ttgccgtatc atttatcggg tggaaggtga ggggactaga gtcttctcta
    45001 ctctttctgc cggagaccat ttagatgtca tgggtccttt aggcaatggt tttgatttgt
    45061 ccaatcttca tacaggagac gaagtattta taatcggtgg aggaatcggt gtccctcctc
    45121 tatatgagtt atcaaaacag ttagtcgaaa aaggaattaa gccaacgcat tttttaggtt
    45181 ttgccacaca tgaagtcgtt tattatgaaa aagaatttaa tcgtctagga gaaacaagaa
    45241 tcgctactga cgatggaaca tacggtatgc acggaaatgt cggtaattta ttgttaggaa
    45301 cgaagacgga acctacagct gtttttgcat gtggttcaaa cgggttattg aagacagtgg
    45361 aacagctgtt ttcttcgcat caaaatgtcc agttatcatt agaatcccgc atggcatgtg
    45421 ggataggggc ttgctatgct tgcgtttgtc atacgccgga agatgaaaca ggaacaaaaa
    45481 gtgtgaaagt ttgtgacgaa ggaccgattt ttaaaatagg agaggtaatt atatgaatga
    45541 gaatccttta gcggtcaaac ttcctggcct agaattaaaa aatcctatca tgccggcaag
    45601 cggctgtttc ggttttggca aagaatacgg aaaatactat gatttgaatc agcttggatc
    45661 gatcatggtc aaggcaacga ctccaaatgc ccgctttggc aatcccacgc caagagtggc
    45721 ggaaacacca tctggcatgt tgaatgcaat tggtttgcaa aatcctggtc tagacgttgt
    45781 tatgcataaa cttcttccag aattagagga gtacaatgag ttacccatca tcgcaaatgt
    45841 tgctggtgct tgtgaagaag actatgtaga agtttgtagc aaaattggcg aagcaccaaa
    45901 tgtgaaagca atcgagctga acatttcttg cccaaatgtc aaacatggcg gaattgcttt
    45961 tggaacagat tctgatgttg cttttcaatt aacacaagca gtaaagaaag tttcttctgt
    46021 tcctgtctat gtcaaattgt ccccaaatgt aacagacatc gttccaatcg ctcaggcaat
    46081 cgaagctgga ggggcagatg ggtttacgat gatcaatact cttcttggta tgcggattga
    46141 ccttaagaca agaaaaccga ttttagccaa tcaaacaggt ggactctccg gaccagcaat
    46201 caagcctgtc gctattcgtt tgattcacca agtagcaagt atatccagcc ttccaatcat
    46261 tgggatgggc ggcgtgcaga cagtggatga tgttcttgag atgtttatgg ctggagcaag
    46321 tgctgtagct atagggaccg cgaatttcac cgatccgtat atctgtccta aactaattaa
    46381 agagctccct gtgcgaatga gcgaactagg catcgaatcg ctggaaagat taatcaaaga
    46441 agtgagagag gaacgtgaac gatgaatcaa ctagaccaac gaccaattat tgcattagat
    46501 ttttcaacta ggcaagaggt agaagacttt cttcgatttt tcccgaaaga agaaaaattg
    46561 tttgtgaaaa tcggaatgga attgttctac caagaaggac ctgaaatcgt acgttatcta
    46621 aaagaggctg gtcataatgt atttttagat ctgaaacttc acgatattcc gaatacggtc
    46681 gaaaaagcaa tgcggggatt ggcaaagctt ggtgttgatc tcacctgtgt tcatgccgct
    46741 ggcggtattc gtatgatgga ggcggcaatg cgaggattag aagaggggac tccagaaggt
    46801 ggaaaacgtc cgctacttct agctatcact cagcttactt ctacaagtga agaagaaatg
    46861 catgccgatc aactaatcga agtttcttta gaaaaaagtg tgatccatta tgctagctgt
    46921 gccaaaaaag caggattaga tggtgtggtt tcttctgctt gggaagtaga agcgatcaaa
    46981 gaaatggcag gagacgaatt tgtttgctta actccgggta taagaccaga aggaacagtc
    47041 gcaggagatc agacaagagt agtcacacct tctcaggcaa aaaagatcgg ctcaactttt
    47101 atcgttatag gtcgaccaat cactcagtca actaatcctt ataaagcata tcaaacgatt
    47161 caaacagaat ggagctaacc taaaatgaat gttgaacaaa gtatcgcaaa agacttatta
    47221 gaaattgaag cagtattttt aaatccaagt aatcctttta catgggcaag tggaatcaaa
    47281 agcccaattt actgtgataa ccgaatcacg atgagctatc caaaagtccg aaaagagatc
    47341 gcaaaaggat tagcaagcaa aatcaaagaa gcttaccctg aagtacaagt gattgctgga
    47401 actgcaacag caggaatccc tcatgccgca tgggtagcgg aaatactgga tttgccaatg
    47461 gtctatattc gaagtaaggc gaaagatcat gggaaaggta accaaatcga aggacgtata
    47521 tttgaaggtc agaagatggt tgtgatcgag gatttgattt ctacaggcgg aagtgtcttg
    47581 gaagcagctg aagcagcaaa aagagaaggt gcggatatcc ttggtgttgc ggctatcttt
    47641 acgtatgagt tgccaaaagg aaaagcaaat ttcgaaaaag ccgaaatccc tcttatgacg
    47701 ttgaccaatt attctgtatt gattgaagca gctttagaag atcgttatat cgatgagcaa
    47761 gaattaactc tgctaaaaga atggaaaaaa gatcctgaaa attggcagat ttaagcgcgc
    47821 ttgatgaaga tagagaaatc cgatttgtgt ctccagaatc atcaattgga atagcaaaaa
    47881 tccaaaaact gattgcgaga agcatctttt catcaggtat gaaaagaaac ttctatcgtg
    47941 atcagttttt gattttttta aaattcattt ttctaagact ggttagcaga aagaagagaa
    48001 taatctcttc tcttttttct attatatata gattttctct attttttggt aagggagctg
    48061 tttcaaaaat ggtaaagagc ggaaatgttg cgaatatcag ttatttaatg atatgatatt
    48121 cggaaaaaga aatctcaaag ggaggtaact tttatggggt tgaatgaatt tattttagga
    48181 ttgaacaatt tagagacgat cacaagggca cctggatttt ttaaatatac agagcataca
    48241 gttgcagcac attcgtatcg tgtagcatct attgcgcaag ttctaggaga cattgaagaa
    48301 gcgaatggac aaccgatcga ttggaaactg ctctatgaaa aatcattgaa tcatgactac
    48361 acagagcgtt ttattggtga tatcaaaacg ccggtgaaat acgcaagcaa agagttaaga
    48421 gggatgctgc aaacagttga agaaaagatg acggacgaat tcatcaacca agagattcca
    48481 gctgagttcc aagaagttta tcgccgtcgg ttgttcgaag gaaaagatga aaccgtagaa
    48541 ggagaactat tagccatttc agataaggtt gaccttcttt atgaatcttt tgatgaaatc
    48601 atcaaaaata acccggaaaa agtttataag gagatgttca ttgaggcagt gactacgatt
    48661 aaaagctttg aacatcggcc ttctgttcag tatttcttta aagagatatt tccggaacta
    48721 ttgaaccagg aattttatgg aaaagaggcg tttttagaaa ccgtctcaac gattgtaaag
    48781 aaagaagaaa aataaaaatg atatgagatg cagggggaag tatagttgaa aaagaatatg
    48841 gatgtcgaat ggggctattc tggagacaaa ggtccggaaa attgggcgag tttatgtgat
    48901 tggtttgcga gaggtgcgga atttccattg cagtcgccta ttcatttgac caagggggaa
    48961 gaaaccaaaa tagaaggaga cacgctttcc tttcattatc aaaagcaacg gtttactgac
    49021 aaggaattca aaaacacgat tcatttagta ccttttgacc aactcagtta tgtagagttc
    49081 aagaaagaac gctattattt gacagatatt catttccact tgccttctga acatatcatc
    49141 aacggaaaac aggaagatat tgaatttcat tttgttcata tgaacagcaa aaaagagaat
    49201 ctagttgtgg gtgtcatgta ccagctaatg gtacaggaag gttggctgta taatcaagaa
    49261 aatggggaaa gttggaactt agaaaaacat gagcattggg taaatccgga tgtgttcttt
    49321 ccggagcaaa aaagccattt ccattatatt ggctcattga caactccgcc taccagcggg
    49381 ccaatccaat ggtttgtaat ggatcatgta ggaaaactga accaagagtt tcttctcccc
    49441 ttcgatggtc agtatgctcg accgaacaac cgaccaatcc agcccttgaa tggaagagaa
    49501 atttattatt tcgaggagtt tgagcaatga atattcagca gatgaaatac gtggtcgctg
    49561 tagcaaacaa tggtagtttc agagaagcgg caaagaaaat gtttgtctcc cagccaagtc
    49621 tttcagctgg tatcaaagaa ttagaaaccg agttagggat cacgctgttt actcgaacga
    49681 atcgaggggc atatttaaca gaagaagggc aagacttctt aaatcgtgcc gagaaaatat
    49741 tggtccagct tgatacatta gaaactcact atctaacgag tgaaaagaga gacaattttt
    49801 cgatcgctgc ccagcattat gatttcttag gtcctttgac cgcacagcta ctcgaggaat
    49861 tcaaagacga gatcaaacaa tttcggatca tggagacgac aacagcgaga gtgatcgaag
    49921 aagtcaaaga gcagcacagt gagatcggca ttatttatat gaatgagcat aatcaagctg
    49981 gtatcagaag atatttacaa caaggagagc taagtggccg cagcattgga aaattcaaaa
    50041 cgcatatttt tttaaggcaa ggacatccat tagctgaaca cgcagagatc accaaagaag
    50101 aattgttatc ttatcctcaa gttcgtttta cacaggatgg aaataatttc ccgtattttt
    50161 atgaagacct tatcgagatc cctgatcaag aaacagtgat ttatacgagt gatcgaggta
    50221 ctttgatgaa tatcgttctt gaaactgatg cttacgcttc aggatctggt attgtgattg
    50281 gagggattcg cgagcacttg cggttaatcc ctttggcaga aggcgaacta aatgaatttt
    50341 atatcattta ttcggcgaaa cgtccgctca gtgaaatcgc tcaaagattt atcaaagagc
    50401 ttactcggtt actggaccag cagagctaag aaaagcagat gagaacgctg tttattgaac
    50461 accgttgatc aaaaaagagg ggttgtgaca gaattttgtc acaactcctc tttttgtagc
    50521 aaacaattta taactaattg ctgttgtggg aaagtacgca aatatgattc tagaaacact
    50581 cattgattac ctgttttgtt tcatagctgt aattttttct tcttctggtg tcacgataat
    50641 cgtcttttgg ttttcataaa taacataacc aggcttggcg ccatttggtt ttcggatatg
    50701 ctttacctgt acaagatcaa ccggcacttg ggcagagtat cggtattttg aaaaataggc
    50761 agctaactcg gcagcttctg taattgtttc atctgagggc ttgtcacttt taatgatgac
    50821 gtgcgaaccg ggtatatttt ttgcatgaag ccaatagtcg gtttttttag ctgtcttcat
    50881 tgtcagctgg tcattttgaa gattgttttt accaacaaga atgagcgttc cgtcagaaga
    50941 aaagtattga tcaggctgag atggtttctt acgtttttgt ttttttaagt tcttcttttt
    51001 caggtatcct tctgaagtca attcttcttt aattgcttcg atatccattg ggccggcaat
    51061 ttccagttga gataagacag attcaagata ttggatttca tctttggctt cttggatttg
    51121 ttcgccaatc agcttaacag cgttcttcag cttttggtat cgatggaaat atttctgtgc
    51181 attttgattt ggtgtcaatg ccggatctag tgctattttg attggccgat cttcttcata
    51241 ataattaggt aaaacaactt cttttgcgcc gcgtggtact tgtgtcagaa aagtagtaag
    51301 tagttcgcca tttctacggt aattctcagc gttttcggat tctttgagtg tttgttcacg
    51361 ttttttcaat ttatttttat ttcgttttag ttcattttcg atttttcgaa tcagttctcc
    51421 gccttgttgt tttgcccgat ctttctctgc tttttcgtga taatagctat ctaataattg
    51481 actgagtgtt ggataagctg ttacagcaga tgcctgttcg gacaatacct gataagcaat
    51541 cggtgtgaaa aaatctttat tttccgtttc gtaaaaagta ggaataggct gatggctgat
    51601 ggctgagaaa aattcgtccc atacaaccat cttttcatta ggacgttcca gtaatctttt
    51661 ggtcagctct tgagcgatat cgaaaccgat tccctgaaac tgacgttgga ttgcttttgg
    51721 atctagttca gtttgggaaa gccgctgaaa gattttttct ttctcggagc taaatgggtt
    51781 caagacctct tgttttggcg gagcaacata ttctacacca ggaagcaaag aacgataagt
    51841 gttttgagag cttccaatgt gtttgatcgc atccagtatt tttccagttt ctcgattaac
    51901 taagacgatc gtactatgac gtcccattaa ttcaacgatc aatatgatat tttgtagatc
    51961 acccaactcg tttcgtttag caaagtggaa atggatcact cgatcatttt cgatttgttc
    52021 gatgtcttct aaaatagcgc catccaaata ttttcgaagc atcatcacga agttaggcgg
    52081 attatcagga ttctgataat cgatttgggt aatctgtaca cgagcataac ttgggtgcgc
    52141 agataataat aatcgatggt ttttgccgcg tgaacgaatc accagcacga tttcattttc
    52201 ataaggctga tggattttcg agatccggcc agatagtaac gtttcacgca attcgttgac
    52261 catcgcgtgg gtaaatacac catcaaagga catggttcat tcctcatttc ttttcataag
    52321 tatattcatt ataacgaaaa aaagaagaaa aaccaatttg gccgaatagt aaagcaaaag
    52381 tctagaaaaa tcttggacta attacataaa aaacagtgtt tctatcgttg aaatccaaat
    52441 tttta
//
LOCUS       DACGMI010000014        51409 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.014, whole genome shotgun sequence.
ACCESSION   DACGMI010000014 DACGMI010000000
VERSION     DACGMI010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.014"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            126..1169
                     /locus_tag="IXT46_000946"
     CDS             126..1169
                     /locus_tag="IXT46_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAQ4946877.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1231..1695)
                     /locus_tag="IXT46_000947"
     CDS             complement(1231..1695)
                     /locus_tag="IXT46_000947"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAQ4946878.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            1941..2888
                     /locus_tag="IXT46_000948"
     CDS             1941..2888
                     /locus_tag="IXT46_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4946879.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(3099..5171)
                     /locus_tag="IXT46_000949"
     CDS             complement(3099..5171)
                     /locus_tag="IXT46_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAQ4946880.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(5104..5481)
                     /locus_tag="IXT46_000950"
     CDS             complement(5104..5481)
                     /locus_tag="IXT46_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAQ4946881.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(5610..6170)
                     /locus_tag="IXT46_000951"
     CDS             complement(5610..6170)
                     /locus_tag="IXT46_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4946882.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            6320..7612
                     /locus_tag="IXT46_000952"
     CDS             6320..7612
                     /locus_tag="IXT46_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4946883.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(7672..8790)
                     /locus_tag="IXT46_000953"
     CDS             complement(7672..8790)
                     /locus_tag="IXT46_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAQ4946884.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(8804..10225)
                     /gene="arcD"
                     /locus_tag="IXT46_000954"
     CDS             complement(8804..10225)
                     /gene="arcD"
                     /locus_tag="IXT46_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAQ4946885.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(10471..11592)
                     /gene="mnmA"
                     /locus_tag="IXT46_000955"
     CDS             complement(10471..11592)
                     /gene="mnmA"
                     /locus_tag="IXT46_000955"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAQ4946886.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLIYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            11996..12595
                     /locus_tag="IXT46_000956"
     CDS             11996..12595
                     /locus_tag="IXT46_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAQ4946887.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(12733..14019)
                     /gene="efmA"
                     /locus_tag="IXT46_000957"
     CDS             complement(12733..14019)
                     /gene="efmA"
                     /locus_tag="IXT46_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAQ4946888.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(14290..14634)
                     /locus_tag="IXT46_000958"
     CDS             complement(14290..14634)
                     /locus_tag="IXT46_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAQ4946889.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(14771..15907)
                     /locus_tag="IXT46_000959"
     CDS             complement(14771..15907)
                     /locus_tag="IXT46_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAQ4946890.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(16096..17070)
                     /locus_tag="IXT46_000960"
     CDS             complement(16096..17070)
                     /locus_tag="IXT46_000960"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAQ4946891.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(17150..18025)
                     /locus_tag="IXT46_000961"
     CDS             complement(17150..18025)
                     /locus_tag="IXT46_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAQ4946892.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            18155..20062
                     /locus_tag="IXT46_000962"
     CDS             18155..20062
                     /locus_tag="IXT46_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAQ4946893.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(20603..23881)
                     /locus_tag="IXT46_000963"
     CDS             complement(20603..23881)
                     /locus_tag="IXT46_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAQ4946894.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(24152..24697)
                     /locus_tag="IXT46_000964"
     CDS             complement(24152..24697)
                     /locus_tag="IXT46_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4946895.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(24709..25401)
                     /locus_tag="IXT46_000965"
     CDS             complement(24709..25401)
                     /locus_tag="IXT46_000965"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAQ4946896.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(25420..25704)
                     /locus_tag="IXT46_000966"
     CDS             complement(25420..25704)
                     /locus_tag="IXT46_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946897.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(25717..26280)
                     /locus_tag="IXT46_000967"
     CDS             complement(25717..26280)
                     /locus_tag="IXT46_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAQ4946898.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            26508..27170
                     /locus_tag="IXT46_000968"
     CDS             26508..27170
                     /locus_tag="IXT46_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAQ4946899.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            27294..28490
                     /locus_tag="IXT46_000969"
     CDS             27294..28490
                     /locus_tag="IXT46_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAQ4946900.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(28591..29967)
                     /locus_tag="IXT46_000970"
     CDS             complement(28591..29967)
                     /locus_tag="IXT46_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4946901.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(30004..30870)
                     /locus_tag="IXT46_000971"
     CDS             complement(30004..30870)
                     /locus_tag="IXT46_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAQ4946902.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(30959..31984)
                     /locus_tag="IXT46_000972"
     CDS             complement(30959..31984)
                     /locus_tag="IXT46_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4946903.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(32002..32676)
                     /locus_tag="IXT46_000973"
     CDS             complement(32002..32676)
                     /locus_tag="IXT46_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4946904.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(32860..33753)
                     /locus_tag="IXT46_000974"
     CDS             complement(32860..33753)
                     /locus_tag="IXT46_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4946905.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(33827..35524)
                     /locus_tag="IXT46_000975"
     CDS             complement(33827..35524)
                     /locus_tag="IXT46_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4946906.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(35517..36830)
                     /locus_tag="IXT46_000976"
     CDS             complement(35517..36830)
                     /locus_tag="IXT46_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4946907.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(36830..40348)
                     /locus_tag="IXT46_000977"
     CDS             complement(36830..40348)
                     /locus_tag="IXT46_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAQ4946908.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(40641..41099)
                     /locus_tag="IXT46_000978"
     CDS             complement(40641..41099)
                     /locus_tag="IXT46_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4946909.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(41396..41914)
                     /locus_tag="IXT46_000979"
     CDS             complement(41396..41914)
                     /locus_tag="IXT46_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAQ4946910.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(41916..42533)
                     /locus_tag="IXT46_000980"
     CDS             complement(41916..42533)
                     /locus_tag="IXT46_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAQ4946911.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(42530..43384)
                     /locus_tag="IXT46_000981"
     CDS             complement(42530..43384)
                     /locus_tag="IXT46_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4946912.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(43381..44292)
                     /locus_tag="IXT46_000982"
     CDS             complement(43381..44292)
                     /locus_tag="IXT46_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4946913.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(44333..45667)
                     /locus_tag="IXT46_000983"
     CDS             complement(44333..45667)
                     /locus_tag="IXT46_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4946914.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            45875..46705
                     /locus_tag="IXT46_000984"
     CDS             45875..46705
                     /locus_tag="IXT46_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAQ4946915.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(46949..47198)
                     /locus_tag="IXT46_000985"
                     /pseudo
     CDS             complement(46949..47198)
                     /locus_tag="IXT46_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(47389..47583)
                     /locus_tag="IXT46_000986"
     CDS             complement(47389..47583)
                     /locus_tag="IXT46_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946916.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(48088..48273)
                     /locus_tag="IXT46_000987"
     CDS             complement(48088..48273)
                     /locus_tag="IXT46_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946917.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(49123..49464)
                     /locus_tag="IXT46_000988"
     CDS             complement(49123..49464)
                     /locus_tag="IXT46_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4946918.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(49464..49694)
                     /locus_tag="IXT46_000989"
     CDS             complement(49464..49694)
                     /locus_tag="IXT46_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4946919.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            49981..50319
                     /locus_tag="IXT46_000990"
     CDS             49981..50319
                     /locus_tag="IXT46_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946920.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(50524..50763)
                     /locus_tag="IXT46_000991"
     CDS             complement(50524..50763)
                     /locus_tag="IXT46_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAQ4946921.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(50739..51086)
                     /locus_tag="IXT46_000992"
     CDS             complement(50739..51086)
                     /locus_tag="IXT46_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAQ4946922.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
BASE COUNT        14932 a        10882 c         9059 g        16536 t
ORIGIN      
        1 ttattcgaaa caagaggtcg tacaagactt ttgtcacgac ctcttgttct tttgtcaaaa
       61 tactggttta gtgctactat gttcgagtat gcttttagta tttattgacg aaaggaaccg
      121 atcaaatgaa atcattgtca catccaataa aatctgtaaa ggattcagcg gtccgcgaaa
      181 tcttacccgg tttactgctt tcttttgcca tcgctgcctt cagcaggctt cttgctattt
      241 atctgccaca gttaggtgga gcgactattg ctattttatt gggtatttta ttaggaaata
      301 ctttttttaa acagcctgtt ctagcaatcg gcacaaaatt tgctgaaagc aaactattag
      361 aattctctgt ttttttacta ggtgcaactg tcacagctca aacgattgct caaattggtg
      421 taaaaggaat tgtttttgtg ttactgcaaa tgtcagtcac tatcatcggt gcttacttga
      481 ttggtaaaaa actgcaattc agcgatactt cttctttgat gatggctgga ggaaacgctg
      541 tttgtggttc ttctgctatt gcttcaatcg ccccttccat ccatgcgaaa gaggaagaaa
      601 aaggacagat catcacacta gtcaatctac tgggtactgt gatgatgttg actctccctt
      661 ttcttggatt acagttgttt ggtggaaatc tcattgaaaa aagtgcactt ttgggtggta
      721 cactccaatc tgttggtcaa gtagtcgctg gggcaagctt acttgacaat tctgttgtcg
      781 aattcgccat gctatttaag attctacgta ttatgatgct cgttgttgtt gtctatctgt
      841 ttgaaaaatt catgcacaag aaacaaccag ctctgtttga aacgccaact gatacgcaga
      901 aaaaacgaaa attaccgctt ccttggtatg tattagggtt tgtgatcttt tgtttggtca
      961 acagcttgtt ttctttacct gtagttattg accaatcggc acattttatc agcagctggt
     1021 ttgagatcac tgctttagcg gcaattggtc tgcgtttaga ctttgcaaaa ttcatgaaag
     1081 aaggtacacg cttcttatct tatggattag ctgtcgggct tctccaaaca gtgatggctt
     1141 tactatttat ttggctgatc aaagtttaga atgaacatga aaaaacagtt gtgattctcg
     1201 catggaacaa tgtccgaatc acaactgttt ttaattttgc agatatcctt ctaacaacaa
     1261 caattggcgt ttgatttcaa ccccatctat tgcgtttccc atatatcctg tcagttttcc
     1321 attttgcccg atcactcgat gacaaggaat aacgattggc aatggattgg ttcgatttgc
     1381 ctgcccaatc gctcgcacag ctttcggact atcaacagca acggctactt ctttatacgt
     1441 tcggatttct ccataaggaa tggtcgacaa agctttccag acattttgct gaaaaggcgt
     1501 acctctcttt atagataaag gaacatcaaa ttcttttctt tttcccgcaa aatattcttc
     1561 aaactgttct tgtgtgcgcg ttaaaattcg ctgattcgct gattcgcttt ctgaaattgg
     1621 ctgaaaagat acagcagtca atccggattc atctgcatct aaccataaaa agccgatagg
     1681 tgtgtgtatt ttcattttgt ttgctcctag tcaatagact ggaacttcct cctttttctc
     1741 tatccaaaac tacttgccaa ctaataaaaa ttgttcttaa aagtttgata aaccgaggaa
     1801 acatggtaaa ctaaatacgt tagtttacaa aaagaatacc tgttctttta cgtaaaatca
     1861 aattttaaag gtgttattta aggtttatta aattttgaat gtaaaccata tataaacata
     1921 cgattgaaag gatagaaacg atgaaagtat caattgttgt cccatgtttt aatgaagaaa
     1981 aaactgttcc tctttttttt gatgaggttg aaaaattcaa aggtgcccat gagttcgaat
     2041 atttgtttat tgacgacgga tcaaaagacg gtacgttagc agcaatcaag aagctagcct
     2101 cagcttatcc ttatgtccgc tttgtctcat tttccagaaa ttttgggaaa gaagcggctc
     2161 tgtacgctgg attgcaagct tctacaggag atttagtgac cgtgatggat gttgatctgc
     2221 aagatccgcc cgaactgctt cctgagatga tcaaccggat cactacttct gatatcgatt
     2281 gtgtcggcac ccggcgttcg actcgtgaag gcgagcctgc gatacgcagt ttctttgcga
     2341 aaaaattcta ccagttgatc aataaaatca gcgatacaga aatggtcgat ggcgctcgtg
     2401 atttccgctt gatgactcgt caaatggtgg atgccgtcct agaattaaca gaatacaacc
     2461 gattttcaaa aggattattt agctgggtcg gatttaaaac agaatatatt tcttatgaaa
     2521 accgcgaacg tgtggctggc gaaacatctt ggtccttctg gaaattattc aactactcga
     2581 ttgatggtat cgtgaacttc tcggatgcac cgttaacgat tgcttcattt atcggcgctt
     2641 tgtcttgtgt cggttctggt attgcaattt tgttcattat tttgcgggca ttgttgtttg
     2701 gtgatcctac atcaggatgg ccttccatgg tctcgatctt cctgttcatt ggtggaatcc
     2761 aattgttatg tcttggaatc atcgggaaat atattgggaa aatcttctta gaaacgaaac
     2821 agcgtcctgt ttatatcata agagaaacag aaaaagtgaa gccaaatgaa ttgaagcctc
     2881 accaataata tacgtcaaat gaagtaaaca tttttttaaa tgaaaaagga ctgtgacaaa
     2941 agtcttgtca cagtcctttt ttccgaataa atggtgttcc agaagtagct tcttcggaaa
     3001 taagccgaaa tttcacaaaa atttgagaag caattttcgt aaattccttc ttatttcttg
     3061 aagctgacca cttctatcac aacctctttc atatcttatt acttcttcat tgctgctttt
     3121 agtgctgctg ctaatgggct ttcttctggt tcttctgctt gtgcatattt tttcagcaag
     3181 cgtcgttctt catgtttggt cattttcttc ttctgctctt ttttatcaag caatttttct
     3241 gtcgttccat cgtatttaca acggaaataa gcaccgtttt taccttcgat gatttccatt
     3301 ttccggtgac attgcgggca tcgatgatta gagacttttg gatcttttct tctgcggtag
     3361 ttgcaatctg aattggtgca gacatagatt ttgccgtcac gtgtgttttt ctcgcgcaga
     3421 ttggccccac attctgggca tttcttttgg gtaatcgaga aatcttgata ttcttgtttg
     3481 cttgatttga tctcattcac caagcgtttt gtttcttttt cgattccatt caagaaggtt
     3541 cctgcttgtt tctttcctgc agcaatagct tcaaggtctt tttcccagct ttctgtcaaa
     3601 tctggtgtta ctaaagaggg atttaccaat actaataatt gcttaccttt aggagatact
     3661 tgcagtcctt gaggggtacg ttccatcagt tcagatttga ttagtttctc gataatctct
     3721 gcacgcgtag ctggggttcc cagactgtat ttttccattt gaccaagcaa gcttgcttct
     3781 gacaatggtt taggcggtgc agatagttct tttttgatgg cgaaatcggg attgattctc
     3841 attccttttt cccatttgac tgtttccgtc tcagtttcag tttcgccttt ccatcctgct
     3901 tggacgacac gattttgccg aaaaatgaat cgttctttac caaattcaac cgtaactttt
     3961 gtttggctga ctttatgggg ttgagcaaac agtcctaaaa aacgagagac aatcatttga
     4021 tagatttttc gctcttcatt acttaatttt tcataacgtg ctctgttttc agttggcaaa
     4081 agtgcatggt gatcggtcac tttactgtct tggaatactt ttgtctgttg gacgatggct
     4141 ccgtttttca aatactgctt gacctcagga gcaaagtcgc tgactgcttg caatcgttct
     4201 ttcatcgtac ttttcatgtc atttgtcaga tatttgctgt ctgtacgcgg ataagtaacg
     4261 atcttatggg tctcatacaa actttgtaca agacttaatg ttttctttgc agaatagcca
     4321 tagcgttgat tggcttctct ttggatctct gttaaatcat aaggcaatgg cgcagattcc
     4381 gtttttaatt tttcttggac ttctgtgaca gttcctttgc ttgtactgat caattgaaca
     4441 agtttttgtg cttcttcttg tgtttttaaa gcaaattgat ttttttgaag cattttggct
     4501 tgttcttttc cagcttgcaa cgtgatcgtg aaatacgttt gtggacggaa ctgctcgatt
     4561 ttcttttctt ggtctctcac taatgctagt gtcggtgtct gcacacggcc tgctgataaa
     4621 ttatccgcgt acttcacagt taaggctctg gtcacattca atcctaccag ccagtccgct
     4681 tttgcccggg caagagcaga ttcatacaat gcatcatatt ctttcgcagg tcttagttgc
     4741 ttgaatccag ttttgattgc tttatctgtt tgagaagaga tccataaccg cttcactggt
     4801 ttattgaaat gcacatactc taagatccag cgagcaacaa gttccccttc tcttccggca
     4861 tctgtcgcaa tgactgcttc tgagacatct tttcgctgag ccagctgctt gattgctttt
     4921 aattgatgtc ctgttttagg aagtggtttg attcctagtt ttttagggat cattggcaac
     4981 gtgtccattt gccagctctg ccattcctta ttcagatctt ccggcatttt caatcctaat
     5041 aaatgaccaa gggcccaagt aacgatcacc ttgggtcctt cataataatt tttgtgcttt
     5101 tgattagcac caagcacctt gcttaggtct ttcgcaacgc ttggtttttc cgctagaatt
     5161 agttgtttca taaaattcct ttctgctttc tactgtgatg ggctgatgat ttttcaacaa
     5221 cgcaagtccc ttgtattgct gtaaatcatc gtcacactct tcacaccagc gctcatctcc
     5281 gtcattccaa aaggcgctga gaaagttact ttttgcattg atatattcat aattttgatg
     5341 gatttcgttc cattgttttt cgtacgcttg tcgtgcttct tcgaaagact cgaatgtttc
     5401 ttcttcttca atatcttctt cccagtcttc aaaaaaccac caaggctcat tgtccccgaa
     5461 catggtaatt acttgataca tactcgtgct ccttctttca gcttttctag actcatctta
     5521 gtcacttttc aagaaagttg caagaatttt ctcttataaa agggtcattt aatgaacatc
     5581 ttaaaattgt tacaaatgaa tctgattgtt taaggcaaag tagcgataaa gttattgatc
     5641 atccaaaaat agctgtcttc tggatcgatt gttggttctt ttgtaaagta tcctaaaaaa
     5701 cgtaaggaaa gataaccgtg gatcatacta cgaagttccc tgcttcgatg aactttttct
     5761 tctttcgtta attgaaaagc ctcaaatatc tgcaaaatga tctgattcgt ttcatggatt
     5821 ccatctaata aaacagcttc attggtatgc ggtacactga tcagtaactc atacactgct
     5881 tgatttgaaa aagcaaagga tcgataagtt tctgcataga tctgcagtgc ttcctgacca
     5941 ctttttccca caagagcccg tcgcagctgg tcattaagtt cctgcagaag tttcgctgtt
     6001 agcgctgttt tgacatcacg aatatttttg aaatggttat acagcgaggg agccttgata
     6061 tccaagcgtt tggctaaatg ctgaaaggtt atttgctgaa catccatctc ttctgctagt
     6121 tctcgaaagc agtcgatgat tttctcttga gacagatttc tttttttcat ttccatgttt
     6181 cctctcataa aataaatcct tcactctttc agtttaccac gaaaaagaaa gagaaaaaag
     6241 agactttcat tgataaacta catattgtag tttataataa agagctgtag atgaaaattt
     6301 tcagaaagaa ggagtctaat tggctgcaag aataaaggaa aaattattta ggaaaagaga
     6361 aacttgggaa caaaacttgt ttgtcttatg gtttggaaca tttatggctg gtatcggatt
     6421 tagtttagtc atgcctttta tgtcacttta catagatacg ttaggtaatt atagtacgtc
     6481 acaattgaac ttttggagcg gattgacttt ttcatctact ttcttggtga ctacgcttat
     6541 ctctccttgg tggggaaaat tagccgacca aaaaggaaga aaattgatgc tgttgcgtgc
     6601 ttcattagga atggcaatcg tcatttcttt gatgggttgc gtgactagtg tgtatcaatt
     6661 agtcgcattg cgtctgcttc aagggatttt ttctggttat atcagtaatg ccactgccct
     6721 tgtcgcaact gggacgccaa aagaaaaaag tggtcaagtt cttggaacct tagcaactgg
     6781 ttctgttaca ggaacattac ttggaccgct tcttggcggg atctctgctt cagcgtttgg
     6841 ctatcgccct acctttttca ttacagggat catcttattt ttcgtcttct tgttgagtct
     6901 gtttttcgtc catgaaaaat ttgtcccagt gaaaaaagaa aacatggttt ctgccaaaca
     6961 gattttcaaa gacttgaaat atccacacgt cgtcatcggt atgttcgtca caacgatgat
     7021 catccaagca tccaacaatt ccattagtcc aatcatcagt ctgtacattc gccaattgct
     7081 gcatggacat gggaatgtta cgttgatcag cggaatcatt gcttcgatac ctgggattgc
     7141 cactttgata gccgctccaa gatttggtcg cttaggtgac aagattggga gtgaaagaat
     7201 acttgcgatt ggtttgggtt ttgcgattct ggtttatatc ccaatggcat tcgtcacgaa
     7261 tgtttggcaa ttagctgcct tacgtttttt gattggtatc tctgatgctt gtctgctccc
     7321 tgctgtccaa gcattgatca caaaatattc gcctcatcaa gctgctggac ggatcttcag
     7381 ttataaccaa tctttccaag caactggtaa cgtagtaggg cctatgatcg gctccagtgt
     7441 ttccagtgca tttggttatc gtggcgtctt tctttcgact tctcttcttg ttttggtcaa
     7501 cttcttgctt gtacgacaca atacacaaga gatccatcag caagaaactg cagaagaaaa
     7561 agcttcagga gtctccatag cttcagggca ctctccttct catagacaat aagcgtaaat
     7621 gaaaaacact gcttgaacag ttgtcacaga ctgtccttgc agtgtttttg tttaggcctg
     7681 ttttttcaag aactcagata agaggaataa tcccttttcc aaggtttctt ttttacaaca
     7741 gtaacctagt cgggcatgct tcggtaaatc aaaggcactt cctggtacta atagtactcc
     7801 tgtttcttct aataaattga tacaaaatgt ctggtcatct tcttcgatgg ctaatttaat
     7861 gaaagaagta gagacgtaat tgggagcgac aagttcaact ttcggttcat tggctaccca
     7921 ttgttttaaa atcacaaggt tctctgtaat gatctttttg tttcgcgcca atattttttc
     7981 tttattcttc aatgcatgta cagcaagatc atctgacagg actccgccgc aaatcatcgt
     8041 gtagtctcga tactttcgaa aaacttctgc caactcaggt ccagtagctg tccagccaat
     8101 acgaatacct ggaatggagt aggttttgga tagggaattg gttgctatac ctttttcata
     8161 gacatctacg atcgacaaga attcaccttt atccgttaaa ggcgcatata cttcatctat
     8221 caatacatat gcatctactg tacgagcaat ttctgcgatt ttttctaaag ttttccgatc
     8281 tagcaatgtg cctgtaggat tgtttgcact attcaaacag atgatttttg tttcaggttt
     8341 gactaaggct tctagctgtt ctaaatcaaa ctgccaatct tcttcttcct tcaaatgaac
     8401 aaagtcaaca gcggcaccta aagatttggg gatgtcatat aattgctgat aagtaggaag
     8461 catcgaaaca acatggtctc ctgcttccac taacgcgtat aaagctaaaa gattagcacc
     8521 agtcgctcca ttcgtttgta agatgttttc cggatcgacg gtttgataaa gagaagcgac
     8581 ttcttgtttg aaaacatctg atccttcgat ccagccatag tccaatggtt cgtttttgcg
     8641 tttttcgaaa aatttactta cgctagtccc atctaagcca acgagttcgt ctaatgtcaa
     8701 tgcttcgatc gagctttgtg caatatcata taccgctttc ttttcccatt tatttagcca
     8761 ttcttctaca ccgaaatttg cgattttcat gtttctttcc cccttatatc ttgatccagc
     8821 ctacagcaag caacccgatt gaaagcagtg cggccacaca aatcagccca atcattactt
     8881 tttcttttcc cgtaatttga tgtttggttt cacgacaagc gatccagtag aagcaaaaac
     8941 caggaagata ggcaatacta cataaaagga cataagaaaa tcctgctaaa atgatgccca
     9001 tcaattcaaa aactacagca atcccaccga tcactacttg ttttttgatt ccttctttta
     9061 aagaaaactg gacttgatag atcccgacaa gtagataaca aatcaaaatt gccgctgtac
     9121 ataaagaata ggcaaattga taggcataat cagtaactaa gaaagtcaat aagaatagat
     9181 tagtcaagat tgcagtaaca actaacgaat aagttggggc atttttttta ttcgtttttc
     9241 cccaaccttt cggcaacaga ccgtctcgag ccatcaacat cgttgtttct gctgggagca
     9301 tcgtccaaga caaccaagaa ccaatgatcg aaataatcaa gccgatattg atcagcgctg
     9361 ctccccaatt tcccacgatt ccttttaaaa tatttgccat agcaggttgt gaaatagttg
     9421 ctaactcttc ttgagataag acgccgtatg gcaagatcga agcaaggata tagataaaca
     9481 ataaacaaag cagaccaatg atcgatgctt gctgggcttc tgaacgtttc ttcgcgcggt
     9541 tggctaaaac acttgcgcct tcgatcccta caaagaccca catcataacc atcaaacaac
     9601 ctttaatctg caaccagatc gttccttgct gccctgttcc attcactaga ttatcagata
     9661 cgttacccca aaaatcagca gtgaatatat tcactttaaa tgcgataaat acaaatatta
     9721 aaaataggaa taatggcact aatttacaga tcgtcacgat tgtattgatg acgctcgctc
     9781 cttcaactcc attgtttact aataaagtca gaccccaaat aaaaatactt gcaaataaaa
     9841 tagaaggaac attttgtcca cctttgaata tcgggaaaaa ttctcccatg gcgctcatca
     9901 gcatcgttgc aaaagcaaca tttcccagcc acgcagacaa ccagtaaccc caaccactga
     9961 tgaagccacc taatttacca aatgaagctt ccgcgtaacc gaaaatacca ccatctagat
    10021 ctggacgctt ttctcctaaa tgattcagcg ataataccaa agctaaaata ccaatcccaa
    10081 cgattatcca tgaaaggatc gctggccctg gagctgcaga actagccaga tcacttgtga
    10141 tcccaaacac accgcttccg attgacgaac tgacaaccag agcaaccagt ccccatttgc
    10201 taatacccgt cgatttcttt tccatttcca tcaccctcac ttataaaatt gaacaaatca
    10261 cttgcaaaag attcccttct attttgcaac tgctcttgct taacaaaaag caactttatt
    10321 catattattg gatattatga actttttaca caagtatttc aagtataaaa tgaataaaaa
    10381 ttaattttat tgcaaaaaaa cagctatgct atccaaaaga aaaggtgttt cttttgttag
    10441 ccatagctgt tttgattcat ttaatatcgc ttaaacgtat tgtaaaactt ttgtttcttg
    10501 atatgcgtgg tcgatcaaac caccacccag acattccatt ccatcataaa atacaactgc
    10561 ttgtccagga gtgattgcac gtacaggttc gtcgaatacg acttctgcac gattatcatc
    10621 caataagcga actgtcacag gaacgtcttg ctgacgataa cggaatttcg ctgtacactt
    10681 gaattctttt ggcattggtt cattcgtcgt aaagtggatt tcacttgcat ccaagcttgt
    10741 ggcatacaat gcaggatgat ggaacccttg ccccacatat aatgtgtttg tcgctagatc
    10801 ttttcctaca acaaaccagg gttcttgcga atctcctccg ccaccgatcc ctagtccttg
    10861 acgttgacca atcgtataat atatcaagcc agcatgttgt cctttgactt caccatcaag
    10921 agtgaccata tttccttttt ttgctggcag atagttgctc aaaaattgtt tgaagttctt
    10981 ttcaccaata aagcagattc ccgttgaatc ttttttctta gcagtcgcaa ggcctgcgcg
    11041 ttcagcaatt gcccgtactt ctgatttttc catgccgcct agagggaaca tcgtttttga
    11101 aagctgttct tgtgataatt ggctaaggaa gtaagtttga tctttattat tgtctactcc
    11161 acgaagcatg tggaccacgc cgttttcatc gcgagtgact tgcgcataat gtccagtagc
    11221 tacataatcg gcgccaagat ccattgcata atccaagaat gctttgaatt tgatttcttt
    11281 gttgcacatc acgtctgggt taggtgtacg tcctgcgcgg tattcggcta ggaaatattc
    11341 aaatacacga tcccaatatt ctttttcaaa attcacagag taataaggaa tcccgatttg
    11401 agcagctact ttcgctacat ccttataatc ttccgtggcc gtgcatacac cgttttcgtc
    11461 cgtgtcatcc caatttttca tgaatattcc gatcacgtcg tatccttgtt cctttaacaa
    11521 aagtgctgtt acagatgagt cgacaccgcc gctcatccct acgacaacgc gtgttttgct
    11581 gttgtctgtc atgatatcac catcatttca attagattct gaaacatcta cgagttgaag
    11641 gtcgcaactt ttcagtattt tacattatac gtcatatttc tgaaaatttc atcccttaat
    11701 tatcaagtcg taaaaatact gttctactgg acctattcag tacacaaaca tgatagtcaa
    11761 ccaaaaaatc actcatcttt tgagcattcg atataaaaaa ttggcatact cataaaaagg
    11821 gccagccttt cggcaataag gaataatttt ataaattgtg aaaaactatt tttcaaaatt
    11881 gcttcttatc gcttaaagct gcacgtctca tttacaacct tttcttttta gatgttatga
    11941 gttgctcaga taagtgattt tgtttactct aagaaaaaag ggaggcaaaa gatacatgaa
    12001 ttactttatc agtgatatgc actttttcca tgaacgctta ttaggaaaaa acgactttgc
    12061 tccgcggctc tttgcaaatg tggatgaaat gaaccaacag ttgatcacta gctggaatgc
    12121 agtaataaaa gaaaccgacc atgtttatca tctaggcgac cttgctatgc atccgcaata
    12181 tgaaaaagca aatgcagaaa ttttggaact ggtcactcaa ctgcaaggaa caatccactt
    12241 gatcaaaggg aaccatgaca gtcgcgcttt tttccgttat ttagaaaaaa atgatcctag
    12301 gcttactgac ggaagtccca aattttattt ttatgatgta ggtgccatcg ttaaattcga
    12361 ccatcaacaa tattacttga ctcattatcc gatgttgctc gggcctaacg acactatccg
    12421 caatcttcat ggacatatcc atcattacag cgtacctatc gagaacgatg tcaatgtagg
    12481 cgtagacgca ccggaaagag aactcttaaa ggaaaaacta ccatttggca ctccgttatc
    12541 tgagcaacaa atcaaagaaa tctatgaagc aaagaggaag tacgataggt cgtgaaaaaa
    12601 ctgccctata tcaagtatta aacaaataaa gataattact catatttttc atttgagtag
    12661 gcttattgcc acaggaacat taggatcaga aatggagttg taacaagact tctgtcacaa
    12721 ctccattcca tactattcgt ctttttgctc atggtgttct tttaccagtt ttttctgtaa
    12781 ttctttatca taatttcggg cagctgacgt taaaaataaa acgattccgc ataataaaat
    12841 cccgattccg gaaaacaaga acattttttc tacccctaaa cgatcagcta atggtcctgc
    12901 aaataataat ccaattggac ctgccaggtt catcaaagag ttgaagttcc ctaagacacg
    12961 acctaaaaca ttcgattcat aactctgctg gatcattgcc atcagcagtg tattgaaata
    13021 tggcgttgca caacctgctc ctgcattcaa gataagaaag tacaagaacc cttgactatc
    13081 gtttggaacc aatccgcttg caccgatcgt caggcccata atgatgtagg ctataataat
    13141 aggtttcatt cggtctttcc atgttcctat aaaactgatc agtgcaccgc ctaagagcat
    13201 tccgactgcg tagactactt ccactgctcc cgcctgtcca acggaaccac caaagtaatc
    13261 tagcgtcatc aatggataca gactgattgc tggcatgaac aacagcatca caaatgcacc
    13321 attgatcgtt atgtaccata accctttatt atccatcaat tgctgcagcc caaattttgc
    13381 atctttaaaa atagtaagcg gaacttccaa tatttcagga gaaacttttg ggatcttcac
    13441 aaaaatcaat aagccgacac caaaaactgc ccccaataca tctaataaaa taaggtaatt
    13501 gacaggaacg actgaaaaca aagccgcacc tagagctggc gcaatgatga aattcgctga
    13561 ttggaccatt cctaactgtc cattcgtcct tgttatgtga gaagatggaa cgattgtcgg
    13621 cataatcgac tggatcgttg gcatttggaa tgtttgtgcg accgaacgca taaacaaaga
    13681 cacaaaaact agccaaatcg ggaaggattc tgaaatcgtt ccgactactg ctaaaataag
    13741 cgcgaaaatc gctacaataa tatccgtgac aatcaaaaga gcttttttat cccagcgatc
    13801 cactagcggt cctacaaatg ggcttagtaa aaccatggga atcattccta gtaaagtagc
    13861 aaaactcaaa attgtcgccg aaccggtttc tcttgtcaaa taccagatga tcgcatattg
    13921 gacgaccata ctagtgattc ctgacaaaaa ctgtcccgat aaaaagaaca aataatttct
    13981 cttccaattc gttaaaacga ccgactgttc attttccata aacatccctc ttttcttttt
    14041 cattttgtat agtgtttgca caacaatcat tatacgggat tcttttttca aaaaatacct
    14101 ttttccctaa ataacaatcg tttcaattta aatttcttta cttagaaaca ataaatcagc
    14161 aaaatattaa aaataacaac atgtgttaaa tttaaaaata aaaaagacaa ctaatttgcg
    14221 tcgtccttac aaagttagtc atctaacaat aggccgtttc aaaactagtt gtctttttat
    14281 atccacagat cattcgactt tttcgaataa cccacggcta atcatcccat ccatcagaaa
    14341 ataaaattta tcttggctca ttttctgttt tggatctttg aaaatattga ctgctttcaa
    14401 tccatttgct gtagtgatcg acattttcaa tgtttgaata tcttttgata cagtgatttt
    14461 taatttgaat ccttctttgc tttgcggcgt ggcatctaat ggtcggatca attgataatt
    14521 gcctccgttt gtttctgtaa atccattatc gcgcaatgta tatctttttg catcaggatg
    14581 caaacgatag ctaattggtg cgcccagtac cgttgctgtt gtttcaaatg ccatgatttt
    14641 cacctcgata aaattagttt ctctttatta taaaagttta tcctgatttt tactaggttt
    14701 ttcagttaag ttccctaaaa aatgaaggcg ttctctcaga catctgttca tataagaatg
    14761 acttcactag ttattttttg acagcacgaa ctaattgatc aaggaaatac tggatgtcgt
    14821 cttcggtatt tcccaaacca aagctgatac ggatggattc ttttagtatc ggtgtatctt
    14881 ctccatacat tgcttctaat acgtgtgaag gctcgatatt tcctgctgta caagctgaac
    14941 cagtagaaat agcgacccca ttaagatcaa gcttcatcag tagcaaatca tttgcttcgc
    15001 caattaagcg aagattcaac acatgaggga gtttattcgt taaatcacca tttacttgat
    15061 aagggatttc gtttgcttct aatgtatcaa gaatcaattg ctggaatcct ttatatttgt
    15121 tgttacgtgc ttcacgttct tcaggtgaca gcagttcaac tgcttttgcc ataccccaga
    15181 tccctgctaa attttctgta cctgcacgcc gcttttcttc ctgctccccg cctaaaagca
    15241 atgcagggat atttactccg tctcgtttat ataagaaacc gacgcctttt ggcccattga
    15301 ttttatgagc agagatactt aataaatcga ttcctaattc ttctggatgg atcgtttggt
    15361 ttccgtacgc ttgtaccgca tctgtatgga aataagctgg atgatccgct aaaagttcac
    15421 cgatttcttt gattggcatc aaatttccga tttcattgtt cccgtacatc acagagacca
    15481 agatcgtatc ttctcgtaac gcttttttga cctcttcgat cgacagattc cctttttcat
    15541 ctacaggcag atatgtaacg tcaaacccct ttgtctctaa atatttcatg gtattaagaa
    15601 cagcaggatg ttcgatagct gtagtgatta gatgtctgcc ttctttttga cgcgagaacg
    15661 ctgtttctaa gatagctgta ttatcccctt ctgttccccc actgttaaag atgatctcgt
    15721 gaggttttgc ttgcagactg tctgcaatga tttgtcttgc tgtttccaat ttttcatgcg
    15781 cgtggcgacc aaatccatgt atgcttgaag gatttccaaa cgtgtcttgc atgattgccg
    15841 tcatcgcttc aattacttgt ggatgcatgg gggtagttgc cgcatgatcc agataaatag
    15901 ttttcacttc attcatccct tccaaattat tgctaggcac attctagcat aaaatagcga
    15961 acaaaccaaa gaagagctca tttttgtcta gaggacgttt catgggcata gaaaaaagga
    16021 gctgtgacaa aagtcttgtc gcagctcctt gaagctgctc acttctgtca caacttcttt
    16081 ccctcttttt tttgtttatt cgaattcttt ttcttccaga cggaataacg gactcatcgg
    16141 tgtattttca tggatgcgtt tgaccgcttc acccattaat tctgaacatg taacgattgt
    16201 taagttttct ggatgacgat tttcttctgt gaaaacagaa tcagtgatac aaatatcttt
    16261 gattggtgca ttgtctaaaa tacttttcgc atgatcggac aataatccat gtgacgcaca
    16321 ggcatatact tcttttgcgc cgttttcttt taatacattt gctgctcgtg caagcgttgc
    16381 tcctgtgttc aagatatcat ctaccatgat acatgtcttt ccttgaacat caccgatcac
    16441 ataaccaccc tcagttgaag catcatctgc atgatctacg atggctaatg tgctgttcaa
    16501 atattctgaa agactacgtg cacgctgaac accgctgttt tttggcgaaa caactacgat
    16561 gtcatctccc gtcagaccta attgacggta ataatgagca aacaacggca tcgtaaataa
    16621 attatctaca ggaatatcaa agaatccttg tacttgaacc gtgtgcagat ctaaagtcag
    16681 tactcgagtt gcccctgctt cttcgatcaa gttagcgatc aatttcgcag tgatcggttc
    16741 atgaggtttc gccgtgcggt cttgcctagc atacccatag taaggcaata cgacattgat
    16801 cgttttcgca cttgctcgct tcattgcatc gatcatgatc agtagttcca tatagtaatc
    16861 attgacaggt gcattcgttg attgaacgat atacacatga tcccctcgaa tactttcttc
    16921 gatattgatg gaaatctcgc catcactaaa ttgcttcacg acgcttttac ctaattctgt
    16981 tccgaacact ttcgcgattt tttcagctaa tggacggttg ccattcaaac taaaaatctt
    17041 caacgtgtca tcctgatact tattactcat gtagtcctcc ccaaaacttc tctattcttc
    17101 gatagtttaa catatttttc caagattttc tgttaatttc agcaaattct taaggaagtg
    17161 aaactgttcc gttactccaa ctggcaggaa tgactttatg ataatcgccc cagttgtcgt
    17221 gtactttgta ataacgttct cctgtttcag tttcaaaata agcgtacgct gtcacccaat
    17281 gattgccata tgtactgcca agtactttca aaataccaat catcacaggt ttgccttcac
    17341 gtatacgttt tgtagctcgc tgccatgaac ctagaagagt tgctcgtgca cgctcatgat
    17401 tgccattctt ctttaaaaaa ctagaaatcc ctgtactaac ctgaaaagga atcgtaggaa
    17461 gtcctagtgg ttggatctgg ctacgcaatg ccttcgtcaa aaccaacgaa tcagccgtat
    17521 ttttcttgcg aatctcattt ggaagcatcc accccttacg atagtcttga taataggcaa
    17581 ggagaactgc tgccgcgtaa gtaccacaaa gatagcctga gggggtagcc catttcttat
    17641 acctcaaaaa acgttcttct ggcaatccca cccagcaatt tgcgagttcc tttcctgacc
    17701 ttttttcttc gatcaaaacg ggaatatctt cttttctgtt gatccatcta gataactcga
    17761 ttggctcttc attgatcagc ttccattttt tacaagaaag accctcttga taagtatatt
    17821 ttgctggaga atattctacc ggatgtcctg attgatcgat aatcacataa ctttgatctt
    17881 caaaaaccag agctaaaaaa agcaatttac tttttcttga ctgcagctgc tgagtgctgg
    17941 ctaatttttt aattttttta tctactttga aatataaagg tttatccact acttgattca
    18001 gttgggatcg cctccttttt ttcattataa gtgaaggatt gaaaaaaaca aatcagtttg
    18061 attgttcgaa ttttcaattt tttatgttct atttgttaat tccttcattt tgtaagataa
    18121 tgggcacacg aaacaaaaaa ggagcgatcg atgaatgaac aaagaacgat tgaaacaaga
    18181 tttctatgaa gcagtcaatg aagaatggca aaaaacagca aaaatccctg cagataaacc
    18241 agctacaggc ggtttccaag atttagttga cgggatcgac caacttttga tgggagaaac
    18301 agacgatctg cttgcccatc cagaaaaagt gtcttcagaa aaaatgaaac atttccttgc
    18361 atattatcaa ctggcaaacg attatgaccg aagaaatgag ttgcatgctc aaccgcttca
    18421 acctataatc gaaaaagttg aatcattgca gtctttcgac gaattgaata agcaatttcc
    18481 agaatggctg ttggatacat taccattgcc atttaatctg gatgtagatg cagatatgaa
    18541 gaatgcgcaa acgaacgcct tctttgctta tccgccttct ttattccttc cagataagac
    18601 gtattatgca tcagaccatc ccaacggtgc acaactaata ggcgttttct ttgatatggc
    18661 tgttcagtta ttagagcttg ccggcaaaga aaaaagtcag gcagaagcaa tcacggaaca
    18721 agcagtgcaa tttgataaat tgattgctcc tcatgtaaaa agtgcagaag aaaacgcaga
    18781 ttacagcaaa atgtataatc cgcaatcttt tgatacattt attaaataca cagataaact
    18841 ggacttgaaa aaacttgtca cgggtttgat tgggacaact ccagataaag tgatcgtaac
    18901 tgatccagtg tacttcgatc atttgaatga catcctgaca gaagctcatt ttccgttatt
    18961 caaaagctgg atgatcatta aaacagtacg ttctcttagt ggttatctat cagaagaatt
    19021 ccgccaagtc agcggaatct attctcgcgt attgtctgga acagacgaag caatgcctca
    19081 gaaaaaagca gcgtattacc ttgcctctgg acaattcgat caagtagttg gcgattacta
    19141 cggaaaaaaa tattttggcg aagctgctaa aaaagacgta gaacaaatgg tgaaaaaaat
    19201 gatcgccgtt tataaaaaac gtctagaaga aaatgactgg cttggggatg caacaaaaga
    19261 aaaagccgtc ataaaattaa ataacttagg tatccaagta ggctaccccg ataagatccc
    19321 agcattattc gaccagttca aaacagtacc tgcagatcag ggtggtactt tgctttcaaa
    19381 tactcttgtt ttcagcaaac tcacattaaa agatcgtttc agcaaatgga acaaaccagt
    19441 ggatcgttca gaatgggaaa tgagtgctga cacggtcaat gcttattatc atccatttcg
    19501 gaatgtgatc gtctttccgg cagcgatcct tcaagcacca ttttacagtc tagaacaatc
    19561 aagctctgct aattatggtg gaatcggagc tgttatcgct catgagattt cccatgcatt
    19621 tgataataac ggcgctttat ttgacgaata tggcaacttg aacaactggt ggacagaaga
    19681 agatcttaca caatttcaaa acaaagcaca agcaatgatc gaagaattcg atggtctgcc
    19741 ttttgctgac ggaaaagtaa acggaaaatt aaccgtttcg gaaaatattg ctgatgcagg
    19801 cggtctaagc tgtgcattgg aagcagcaaa aacggaatca gatctttcta tcgaggaatt
    19861 ctttgtcaat tgggcaacga tttggcgtac aaaagcaaaa aaagaatacc aacaactttt
    19921 actgcaaatc gatgtccatg cccctgctaa actccgagca aacgtgcaac caaaaaacct
    19981 tgacgaattc tatgaaacat ttggtatcac ggaacaagac gctatgtatc tagcgccaga
    20041 aaaaagagtg cgaatctggt aagaggttgt gccagaagtg gtcagcttca agaaataaga
    20101 aggaatttgg gaaaatcgct tctcaaattt ttgtgacatt tcggcttatt tttcgaagaa
    20161 gttacttctg gaataccatg tattagaggt tgtgaaaaag ctgcttagtt tcaagtagta
    20221 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttgactt actaccgaga
    20281 aactggcttt tgaacaccgt ttatcgagag gttgtgaaat cagcgtcctg acctgagtat
    20341 tagagaaaaa aacggaaaaa tagttcctca tattttgccg tttgttgagc taataccgag
    20401 ggtcagctga ttgaacaccg tttagtggag agattgtgaa aaagctgtcc tgcatcaagt
    20461 aataagaaca gccaatcaaa agcagcaagg agaacctcat ctataaaaag atagaaggaa
    20521 gtgagacatc tattggtctc atttccttct atttttactt tcctcagtca attgttttac
    20581 atcataaaag gagaaattcc acttattttt ttcgctgttt catgacataa acaactacac
    20641 cgattaacaa aattcctcca gctaatgcta gcaacgggtt attaaattct cccgtttttg
    20701 ggagtccttg agtgccattt ttttcacttt cttttgctgt cctatccgga tgagaaggtt
    20761 ttccatttgg ttttccattt ggtgattcat ttcctggatt ttctctttct ggtttgtcat
    20821 ttcccggggg cacatcggca gtttctcgca cagtgatcgc tttttgctgg gtaacagatt
    20881 ctgtatgagc agaccatttt tccccatcaa atatttccga acgataagtg acttctagcg
    20941 tatattctcc ttttgaaggt gctgaaaaaa tagcggtatg attagaaaat tgagcacttg
    21001 actgtgtttc aacgatttgg atcttttctg ggaaataacg catatcttca aagacaggcg
    21061 ttccttgatt tggtgtgaaa gttgacacaa aaactgtaaa aggcttcagt tcaatgatat
    21121 ttccttctgc attctccgcc acaccatttg cttcttgtat aataatcgga ttattttgtt
    21181 catttggttt tgtctgattt ggttcttgta cgattgcata ctctggatat tccgaagacg
    21241 gtgaggtttc tccgtcaaaa atagcaccta cagataatgg aagaccatcc actctttcct
    21301 tttctgtttg acgattcccc ggtttaatct gcatcagtcc atgaacatgg atacttccat
    21361 tttcatagcg cgtaacaggc tgctgacctt ctttcgaaca tgtatttaga gactcgatcc
    21421 aatcttttga tatggtatgt ccaagagtat tttctgattg tttctctcgt tcattccaat
    21481 agtagttcaa cgagtggtag atttgatctt cgttttgatt caatgggcgg atctgctctc
    21541 tcatctcaag attctctgtt cggaaagata agataccaga agcatggtag tctgtgtttc
    21601 ctgctgaaga ggtataaaga gccacattat atgaaccgtt attaaaactt gtactgctat
    21661 tgacgataat atctgttccg ctattggaat cgattccttt cgcaagattt tcgaaagaca
    21721 aactattgat caattcatga gggcccgtta aagaagaacc gcccattttg aatccattac
    21781 cgttaccttc tccctcaatt cctggtaccc agccgtttcg ataagcaact gagtttttga
    21841 tgattacttt tccgatcgaa cctgtttcat ttttagcaaa aaggtcccaa ccgtcatctg
    21901 cattatgata cgcgatacaa ccgtcaaata catttccttc tcctattgtc agtttggccg
    21961 caaatccatc ggcatcttca aatcctggat cggcattttc aaaagatgta cagttcttga
    22021 ctaagttatg cgcgggccat gcttcgaaag gatcatttga gctaccgctg atttggattc
    22081 ctgtatttcc attccgataa gcatgaatct cttcgatcaa attatgattt ccagaaatct
    22141 gtaatccttt ttgcatagct gcactatttg taatgtcaaa ccctcgtaaa ccccagtagt
    22201 gactgaacag tgtcatccca tttccagttc ctttaaaatc aagtacagga cgcttgtttt
    22261 ctggattttt ctctgcaatc aactgaatcg ggttttctct tgtcccgtta acgccttttg
    22321 gaatcgtcaa tcctctttcg aaggaataag ttccaggcgc catgacgatt gtctgcccag
    22381 catatgcgta tctcaatgct tgtgtcagag ataatggatt ttgtctgctt ccgtttcctg
    22441 catctgaccc ttctggtgtt acataaactg tcgaatattt aggtttacgg tagtccactg
    22501 tatgaagaat ctcttttgtt tcataactag tcatctctac gtattcttct ggcggatagt
    22561 ttttatctgg cgtaaaactg aaagtaaatt cgttcgttcc ttccatcagt tttgtctgat
    22621 aatcaaattc ccgattcgca gtgatagcca agttttttgc gttcttaagc acctctcctg
    22681 ttgctttatt tttaattgtc aataatccgt cagcatttgc tctaaaggac atagtatgat
    22741 cttggtttcc tgaatgatta ctagaggtca cagtgtaaat cggatcaatc aagcgagtag
    22801 gtctttcttg cccaggagga tctgtcgcag gatctgagta agcaacttcg attccttcta
    22861 ccttgatcgt catattcctt gctgcagcaa atcctgcata aataaccgat tcatctgaag
    22921 cgtataattt ttcccagtca tacatgatgt cagaagccat ttcttctcct gtttcaggat
    22981 cgtaataata tgcctctaaa ccagtattcg tttttttcat ctctacgtcc agtttagtaa
    23041 tcgagttcgt ggccggaaac agattcccat gaccgtttcc gaatatatta taagaacctg
    23101 tttctttttc caagaaccct gctgaagtct ctaaaggtgt tgtttccact gagacactcc
    23161 caggagctgg cgcagcttgc ggatcttcag atgatattcc tgtgattgcc cgtgtcccca
    23221 atccaagtcg catcgtatat ttgctgccgc tcgtgttgac cacttcttgt ctatccgagt
    23281 cccagacata ttcgatccga ctgcctagta tggcaaatga atttgaataa aatgcctgcc
    23341 caaacaaatg attttttggt actgcgtctc ttaccattaa agcaaatcct tcttgggcat
    23401 tcgtataggt ccaagattct atttcgatcg tcgcccgcat cctaaagttg atgtctttgg
    23461 ggattgcttg ataataatag gtcattccat ctgatccgct tgactggaat tttccgccgt
    23521 tattcgtgga agagagccgc acgccgtctt ctaatggttc aatggcatac ctactagcac
    23581 ttgtgctttc tccgaaaaca acccctttcc actcttcatt tgcttcttca gattgctttt
    23641 ttgtcttttc attttctgat tctttcatca taggatcatt tccttcttcc gtatccatat
    23701 cttcactagt tcttggtatt tcctccattg ttgacatccc ttcaatgttc acgtgtgcat
    23761 tttcttcgtt cacagactgt tgttcgttag cagcaacttc aacgacagaa attaaaaccg
    23821 gggtactgag cataaggaga ttcatcatta gcgcactgta ttttatacgt ttttttaaca
    23881 agtgtattcc tcccgtaaca aattagaaag cgtttactta aagtattacc taatttattt
    23941 ttactgtcaa taaaaaacaa aattataata agtgtatttt ataaaaagaa aaaatataac
    24001 ttaagttgtt gataataaag agatttatta acgtaaaaag aataagtttt tttaaaataa
    24061 cgtataaaaa agagcataaa acaaagtcgt ttgttttatg ctcttctttt attattttgt
    24121 gctttttatt ttatcaaatc actttgtttt tttataaaat ttctgcgcct agtgtggact
    24181 caaaatgtct caatgcccat tcatgtccaa cgggatcgaa acttgccacg gcatctttga
    24241 aaatatggag tttgtatcct agattatacg catcgactgc tgtatgcaac acacagatat
    24301 ctgtacatac gccggtcaaa taaatatctg tgatctggcg ttctcgcaaa cggatgtcta
    24361 gatctgttcc actaaaagcg gaataatgcc gtttgtctat ccaataaaca ttttcctctt
    24421 gctcatagtc ttggtataaa ctttttaaag agccgtacaa ttcccgtcca cccgttccta
    24481 tcacattatg cggaggaaat aagcggttct ccggatgaaa ggaatctttt ggatcatgcg
    24541 catcaatggc aaaaacgaca aaatcctttt gatcaataaa cttctttgta tgagcagtca
    24601 gctttttttc aattacttgt cctgctgtcc cagtagtcag ctttccatcc tctgcaacaa
    24661 aatcatatgt gtagtcaatc gagatcaatg cgttcatctt agtcctcctt atacgagatg
    24721 tttgacaaat tcgatcacca tttctgctga tcgtttgcct gcgtcttcga taaattcgtc
    24781 aaagctttgt gtcgccgagt gatctgctgt gtcgctcatt gcacgtacga tcaaaaatgg
    24841 gatattgaac tgacgagctg tttgtccaac agcggctcct tccatttcgc aagctaatgc
    24901 ttcagggaaa ttcgttaaga tttctttgat tttatctggc gagtcgacaa atgtatcacc
    24961 tgtaacgatc aatccttctt ttgcgttcaa attcgttgct tttgctgctt taaccatttc
    25021 actgcgcaaa tatgtgcttg cttcataata tagaggcatt cctggtaatt gtcctgggtt
    25081 gtagccaaat cctgttgcat ctgcatcaaa ataagctact ttgtctgata taacgatgtc
    25141 acctacttgt aagccttcac cgattccgcc agctgaacct gtattgatca ccatgttcac
    25201 gccgtattgt tggatcaaca gacttgtggt aatagatgct aagacttttc ctataccgga
    25261 acgtacgacg atcacttcgt ggttacctaa tgaacctgaa ataaataaag cgcctgcgcg
    25321 ttcccatgat aatggttcgc ttaggttctc tctcaaaatt tttacttctt cttccattgc
    25381 gccgataata ccgattttca tctttttaat tccttctttc tatataaatg cgattgctaa
    25441 aaaaaccaca cataacatta ggataacaat aataagagat ttcatcaaaa aagagttcca
    25501 tttggtcgtc ttttcccgtt cgctgatcct tgttttcgtg attggtttat tctttttgct
    25561 ttctttacga taaaagctgg caatcttttt ttcttcttgc tgataagctg tttctgcttt
    25621 tcgctgtttt tttaatgact cgcttgcttg tgcttgttgt cgcttgcgaa gttcgcttcg
    25681 cgtaataagc ggtcctttgg ccataagccg atccctctac tttcctttgg tcaatagttc
    25741 ccagtattga atcgcataaa tcgtctttgc atcacaaatc aactgatctt tcatcgcttg
    25801 ttgcgcctct tcaagagtta gatgatacaa ctccagtact tcgtcttcat cttgtgctaa
    25861 aggattctcg accttctcta ccccttgtgc atgataaata tgaaggactt catttgcaaa
    25921 acctggtgaa agatacatcg aagtaagatg gctcagcgac ttcgcacgat agccagtttc
    25981 ttcttctaat tctctagctg ctgtcatttc gggattttgt ccttctcctg gatcgatttt
    26041 tccagctgga atctccaaaa tcactttttc taaaggtttt cgaaattgtt tgacaagaag
    26101 cagacgatct tgttcgtcaa aagcaatgat cccgacaccg ccaggatgaa ataccagttc
    26161 tctcttcgaa gttcctccat ctggcaaacg aacttcgtct acagcaacat caataatttt
    26221 tccgctatag atttctttgc gactgattgt tttttcttca aattgctcat tgttcagcat
    26281 atcttctcct gctttctttg taatcataac tgcttttttt tcatttttca atttttctca
    26341 aaaactcctt attagtttac catagataaa ccttagattt tctctaaata tagaaaatcc
    26401 ttctttagtc cgatactctt tatagtagtc cgtatgctaa aataagtatg taatcgaata
    26461 acgaaaagaa ttcaatactc aacgataaat gacatggagg gtttattatg ataaaacgaa
    26521 attggccgtg gcttctagca ttggtcttgc tatttctctt tgtccgaaac aatagttttt
    26581 cttttgttct aggactttta ttgataggtg tagttttagt tttgtgggga ctctttggtt
    26641 cgcgcaggaa aaagggaaaa caagaagaaa ttcctgcact gactgacgaa cttgaaactc
    26701 actatgaaaa aagcggtatg acagcgaatg aaatttcatt ttttcgacaa acaatgaatc
    26761 aaacaaaaaa tgagatcaat caattgcaaa tgaatatgca gcagacagcc aaacttaaag
    26821 caatcgatct ccgccatgat ccagtcaaag cagcgaaagc tttattcaaa gaattggtga
    26881 aagaaccaaa ccgactgcat gaagcaagtc agtttcttta tacgcatctg ccgaatctag
    26941 ttgatttgac aaataagtat aatgagatca atgaccatga gatcaaaaac aaacagacct
    27001 atgaaaaact agaagaaagc gcgcagatca tcgaccagct gtcagcttta atcgcacaag
    27061 attatcaaaa attcgttgct gaggatctag atgatatcga cgtagagata tctgttgcga
    27121 aacagagctt aaagcgtgat aataaatatg aaccagaaca aaaggattaa ctcttttgtt
    27181 cataaaagaa gactcggaac attcagatga tgtctggctg tttcgagtac tttttctaaa
    27241 gtagagacat tcatgtaaga atcgagaaca gattcaacaa ggaggaattt tttatggatc
    27301 ataaaccgac tgaaacaaaa gatgttacac cagttaacga tacacttgaa gatttattga
    27361 acaacccgtt ttcaactcca acagatacgc tgaccacttc acaacaagcg gagattgatc
    27421 agctccaaga gcaacagaca gctgctcgtt taattgacaa actaccggcg gaacgccaag
    27481 aacaagctaa acagctagca gcaaaaatcg atgctaatga tgcacagtct gtcatcagct
    27541 acggatcggc tgcccaagca aaattaagtg aattctcaca atcgatgttg aatcatgtgc
    27601 aagcacaaga tattggtcct gtaggagatt ccttaactga actgatgtat cgtctccaag
    27661 aagccaatcc tgacgaactg cgtgccggag aagggaacat cttccagcgt gtcttcggga
    27721 aggtcaaaca atcgatctat gaagtgacag caaaatatca aaagattggt gcacaaattg
    27781 acaagatttc agtgaaatta gataaagaaa aagacggtct gctaaaagat aatctgatgt
    27841 tagaacagct ttaccagaaa aacaaagact actttgatgc actgaatatt tatatcgctg
    27901 ctggagaatt gaaaatggaa gaacttcaaa caacgatcat tccagaagcg atgaaaagag
    27961 cagaagaaac tggcgatcag atggatgttc agattgccaa tgattacacg caattcctag
    28021 atcgtctgga taaacgtacg catgatcttc gcttagctag acagatcacg atccagcaag
    28081 caccacaaat ccgtttgatc caaaacacaa atcaggcctt ggctgaaaag atccaagcat
    28141 ctatcgctac agccattccg ctgtggaaaa accaagtcgt gatcgcattg accttgcttc
    28201 gtcaaaaaga tgcagtaact gctcaacgcc aagtctctga aacaacaaac gacttattga
    28261 agaaaaattc agaaatgctg aaaatctcag ccatcgaaac agcgaaagaa aatgaacgtg
    28321 gaatcgtgga tatcgagacc cttcaaacca ctcaaaatga tttgatcgaa acaatccaag
    28381 agacattgcg tatccaaaaa gaaggaaaag aaaaacgtcg tcatgcagaa gtagagcttg
    28441 gacacatgga agaagatctg aaacaaaaac tgttggattt aacccaatag atcacctttc
    28501 gcttgttact aaaacaaacg cccaacaaca gtttattaca actgttgatg ggcgtttttc
    28561 ttatctttct tctaacttct ccattggagt ctatttctca ttcatcttgc tgtgtccata
    28621 gccatagcca aaataaatga tcagtccaat aaccattacg ataccgaaca cgatccatgt
    28681 cacagtttgc agacgaagca tcaatacaat acaagtcaag atggagacga ttggcaatag
    28741 cggaacgaat ggcactttga attctccagc ttttggtttg ccaaacattt ttctcaactt
    28801 cagtaagcct agactaacaa gcatcaaata ggcgagcgcc atgatattcg ttagttccgc
    28861 taatacattc aatgggaaaa atccggcaaa gaatacagct gccacaccag cggcataagt
    28921 cgcttttttc ggtgtacgat gcttttgatc gatttctgtc ataaacttag gaagtaagcc
    28981 atccttgctg acagcaaaca gtaaacgagc aagtgaatac atcatcgaga tcgttaccgt
    29041 cagtagcgtt aaaattgccc ctacagcgat caccgcgccc actgttccat gtcctacata
    29101 cctcattgca aaagccactg ggtcattgac tcctagttca gtatacggaa cgattcctgt
    29161 caagatcagc gtcacgatga tgtaaaggac agtagcaatc agtatcgaac caatgattcc
    29221 tcttggcaca tctttttgcg ggtttttgac ttcctcggct gccattgcaa cggcatcaaa
    29281 tcccaagaaa gcaaaaaaca caagagctgc accatctagc acaccggaaa aaccaaaagg
    29341 catgaatggc tgccagttat caggtttaac gaaaaatatt cctacaatga taaacaacgc
    29401 gatgatacca aatttgacat ataccatggc attattcaaa cgtaatgctt tcttggcttc
    29461 aagcgacacg atgtaagtga cgaatatcac tacgagcacc gcaatcaagt caatgtatgt
    29521 accattttcc ggattgtacc cgccagttaa tgcttgtgga agttcggccc ctaaactttt
    29581 caaaaaacct tgcatatagc cagaccatcc ggaagcaaca gaggaaaccg ctagtaaaaa
    29641 ttccccgatc aacaaccacc ctgtcagcca ggcagcaaat tcaccaaata caacatacag
    29701 ataggcatat ggcccaccaa tcactggcac tcgcgaagca aattctgcga aacttagtcc
    29761 agacaaaatg acaacgattg cagctaagac aaatgaaagt gacagtgctg gaccagcatt
    29821 ttgattggcc gcaacccctg tcaccacaaa tattcccgta ccgatgatcg caccaattcc
    29881 aagcatgatc aaatcagacg tttttagttc ttttttcatc tcactcgtat gattgagatt
    29941 gatctctttc ttacgaaaca aatccattga agttcctccc cattttaggt tggaaaacag
    30001 cgattaaact gttttcatat accctaaaag gataccacct aaaatgacta aaaggcaacc
    30061 aacaataaca taaatgagct cttttttcgt ttttctttcg ccaaggatga aaatcccacc
    30121 taaagtagag ataatgatcc ccatttgtga aagtgagaag ccaacagcta aaccaagtga
    30181 tttgactgtt agaagcatgc agatgtttcc taagccccat aataatccac agatcatgtt
    30241 tttccacaca aactgatcga ctttaacttt acggaaagca aagaagcttg cgcctaagat
    30301 cattccgata ctttgaggta agataattga catcgcatcc aaattcgccc agttgacgat
    30361 gatggtatat acaccataac caatcgtaga gaagatcaat gctctaaaac ccttaccaaa
    30421 atcaagcatt ttattatctg tatctatttt tccttcgtca tcttgtcggg cagtcaaata
    30481 cgcaccgctt acaagaagag ctaaagcaat aataccgtat acataatctt tcgtttgtgt
    30541 ccattcatgg aagaaaacgg ctcccgcaat cgtattcaaa attaattgaa aaccagtaga
    30601 caatggtagc cctacagaaa cacccatgta cttcattcca tggaactgtc cattttgtcc
    30661 aacactccaa gctaagccgg ataaaaatcc gatcaagaaa atccaagggg tgattacagg
    30721 actaacaacg aaaaagacaa ctaaagaaaa cagaaatgca ccgatcgtca ttcctagtgt
    30781 ttgttgattg gcatcgccac caattttacc acttactaaa ccaatactac cccatgccaa
    30841 catagggact aatgctatta aaatttccat aaccaatctc cttttatttc acatgataag
    30901 aaacttatca gcgaaaacgt taacaacaca agcacttttt ttcgtttcta acgattttct
    30961 aacgtttttc attataaaaa tttaagattg ggaaaaataa agtcattgtt gtcccttttc
    31021 cttcagttga ttcagccgtc aaatggatac ctaatttttc ggccagattt tttgctaaat
    31081 aaagtcctaa tcctgttgaa tgtgttttgc taagtcgacc atttctccca gtaaatccct
    31141 tatcaaagat ccgtttcaag tcttccgctg ggataccgat ccctgaatct ttaactgaaa
    31201 ggctgactcc ttgcgcttcc ttttctatgc tcacaatgat gtttccgtga tccggcgtat
    31261 atttgatggc attactaagc aattggttga agataaaagc gatccattta gcatcggtca
    31321 aaacagtatg atcctcacca acgatctcgt agcgaatatt tttttggata aaataatttg
    31381 cctgactgcg tatcacaggc tgaatgattc cttttagtcc atattcttgg atgaggtagt
    31441 cccgcgagaa actgtcgagt cttgcataat acaaaacttg ttctacgtat tcatcgattt
    31501 ttgataattc attttctagt aatgtatact tttgatcgtc aatatcgaac tcgatcgaac
    31561 gaactagcaa tttagaagcg gaaagtggca ctttgatttc atggacccat gagtcaatat
    31621 aatctttttg gtcttgttga ttactgattg ctgattgcat tacttcttgg tgttcacgga
    31681 tcagctgatt gatatattct tctaccagtt tttcttcttc tgtcctccca ccactcaaat
    31741 aattttgcaa aggggaagtt ttttgtatgt cggctaattt tccccaccat cttctcttgc
    31801 tcaagtaacc acccagcaga taaaaaatca gaaagacgcc ctcaatcaaa gctaaataag
    31861 caattgtgct caaatcaact ttgatgtttg gcgccagcca catcacaaag atcgtcaatg
    31921 caataaaaaa cagccatccc aagatcaatg tccactgatc tttcaaatat ttaaaaaaat
    31981 tcatcttaac cgctcatcct ttcagggaac gatatatccc tgtcctactt ttgtttcgat
    32041 atatccttgg atacctgcct gttcgatttt tcggcgtaac cgattgatgt tgactgtcaa
    32101 tgtattgtca tctacaaatc gttcgtcatc ccacagtgct cgcagcaatt tttcccgact
    32161 taagatcttt ccattgtgct tcatcaaaat aaataataga cgatattcat ttttgctcaa
    32221 atcaatgatc tctccgttga tttccatact tccgttgtca acattcaacg taatgccatt
    32281 gtggctcatc atttcactag ataattctgt gtagttgtaa gaacggcgaa gtaatgcatt
    32341 gatttttgca atcagtacat cgatttggaa atgttttgtc acaaaatcat ctgcccccat
    32401 gttcatagcc atgatcatat ccatattcgt attcctgctg gagataaaaa tgatcggtac
    32461 tttcgatact tcacgtattt tttgacacca ataatagcca tccaaaacgg gaagattaat
    32521 atctagtaat acaagctgtg gttcttctct ttcaaagtct gagaacactt gattgaaatc
    32581 ggtcgttcca aaggtttcaa attgccattt ctcaagttcc tccatgatca attgtcgaat
    32641 gatctcttcg tcttcgacta ccatgatttt tgccataaaa aatccctcca tctttcttct
    32701 tgctactaca atatcaaaga agcccttgtg aaacaagttg gcttacctgg aaaatgtcat
    32761 tttagcaaac gttaaaaaaa actggaaata tgcgatttaa tcgcgtttgt ctcttccaag
    32821 cagcttaaat ttattatgtt attcttaata attggtctat tatctgttat ttttctttcg
    32881 ttgtttttgt cttttaaatt ttcgataaca ccaataaccg aaaagcgtta gcactagcaa
    32941 tatacctaga aggagtataa gtaatcgata aagatggtat ttttttgtct gttctatctt
    33001 tgaagagact tcttctgtaa agggaactcg tcttcctgtc actagtaatc ggtgagtgtt
    33061 cacggtgtaa ggtgtacaag tgataagtgt gactagatcc tgcttttctc taattgctaa
    33121 tgtatttgtt tttgttggaa ggacaacaat tttctcaacg acttcataag cgagcatccg
    33181 accatacact tcaagataga atcggtcatc ttgctccatt tcttcaagat ccgtaaagag
    33241 ttttttctca gcaataccgc tatgggcggt aatcacggaa tgtgtactct ctcctccagt
    33301 tggaaaagag gtgccttgca ggactgtcgc tcctctatct aacaaaagat cattcgtttc
    33361 atcaaataaa ggcaagctaa cattgatttt cggaatatag atggctccga tcatatgttg
    33421 ttcgtaatat tcttttcctg gattttggac atttctaacc gcttgctcaa aaggatcttt
    33481 gacttgtccc attcctggga ttactgatgt atgagcaagc gtctgatttt tcttttcatg
    33541 cactgctaat tgttgctcat gtttttcttc tttatcgcgt tcaagctgct tttgataatt
    33601 ctcgatcctt ctttgatcca aataattgct gagagcatct gctaaaaatg gatatgtaaa
    33661 aactgcagct ccggcaagaa acatcactgc cataaataat tgtaataaaa gactgatttg
    33721 ggtttgaggt ctattaccta ttttcttttt cattttcttc accttcttat ttaaaaaaac
    33781 tgcagcaacc tttataaaac cgattgctgc agcttatttt tgttgcttat acttcagact
    33841 tcattttaga tttacggtac cagctgtacg ctccaatcat caaacttatt ccgattagta
    33901 agaatgccaa gagcccgttc ccaccagtag caggaagtga cccgcgtttc atattcggta
    33961 ctctttctgg ccctggattt tctactccta cgatctgaat ttcttcatta tagcttccat
    34021 aagagatgat aaattcagta aaggctgcct cacctgttgg aagtacataa ccttctggcg
    34081 ccatggtctc tttcatttga taggttccat aatctaaccc ttgaacctca aagtatccat
    34141 ttccatctgc gacaaattct gttgcttgtc cgcttgttgc ccactcaatt ctatctgctc
    34201 ctgattcata aacagctaaa ggcgactccc ctttataaaa tattgcgtat tcagaacggt
    34261 cttcattcca caattcgaat cttgcatctt taagcaattc actgcttgat gcatcatatt
    34321 tttcaaactt tcttccacct gttgtgactt tctctggcgg ctctactcct tcttcataat
    34381 caaattcatc atttcgtccg atttcaataa ccgctgtgtt gttatggaaa tcatccgctt
    34441 ctagttctgt ggaaaccttc aaattatacg tgatcgttaa atctcctcca cgtgcatctg
    34501 ctaatctacc taaagtatct actttggcta ctccattttc ttctgtcaaa atcgtcacga
    34561 caaacccgtt gcttactact tctactatat aatcttgtcc ttttgttaaa atcgtctcgc
    34621 cggctcgcac ttctatttcc tgatcataat aagttagacc aactgtaggc gtatctgtga
    34681 ttttgtaatt tttgataaca gcgcttccgt tttcaaggac agaatcgatg aaataaggaa
    34741 taggtgctgt gatcgtgtaa gaagccgttt ttcctctttc tagatcaata taagaaatcg
    34801 tttcttgttc tccagcttca ttaataatcg ttacttgtct aaggtcgctt tcctctacat
    34861 tcatctgttt atctgcttct ctgatttcgt ttttcggata caaatgcaca tctgtattgt
    34921 atgtgtcttt ccatgtagaa ccatcccaca cgccatccac catatcaggc atcatcactg
    34981 gcatcataac aaccattgga gacgcgattc tggaaatatg agctggcgaa taagtttcta
    35041 agaaaagata gactttatct ctagaagaag gtgcttcttc cgtcacttgg acggtagaga
    35101 ataccgcttc tccagcttca ttcgttgttt gtttgtcaat acttgtcagt cgatatttta
    35161 aaaaccaact ttctgtgtgc cgtttttgaa tccattcaat cgcttcggca gaattaagac
    35221 cgtcttctcg ttccggtgtt aaaggattat ctcgaatcaa atcgtaatat acttccgtta
    35281 cgtcaaacaa atcaaaatcg actcctggaa tattttcttc accaaaatcc gtagaaacca
    35341 atccgctatt cggtcgttct tccggaacag atgagaaacc ttttttgtgt aatgtaatcg
    35401 tcacttcact tggtttttgt gcgacttctt cggctttgac tagttttccg ttcccgaaaa
    35461 tccctattcc cgcagtaacg agtaacagta cactcattcc cgtgacaatc atttttttat
    35521 tcattttttt ctccccgttc tttttttatt aataaaacag cacctaacaa taaaagaatt
    35581 cctagtaaag aaatcaacgt tcttgcttca ttcgtttgcg ggaatacgga ccattttcct
    35641 gattgacctg gattgcttgg accactcggc tctttcggtt tgtccgttgt ttcttttacg
    35701 gtctcgttat aaacacgtgg tgttgcggat tcataggcag agactggaac tttcccggat
    35761 tctaattcag ccatctcctg tccgttaact actacatatt gtggttggcc ttttgcatcc
    35821 acccaaaatt cagggatgat gacctcgatt ctcttacttg cttcatccat ctcgtaacct
    35881 tccacacctt ttaattcttc aaaataatag gtgccagaag gcaagaaacg ttgtcctgtc
    35941 gtaacaaggc cctctttatc cgaaatgaat ttgcttacat ttttgtcatt caaaggatca
    36001 ttgtctgctg gtttgatcca ttgatttttc aagtcattag caggagccat atctaaataa
    36061 tatttccccc cttctatcat ctgatataga gcaaaaacag caccttctaa tggttttcct
    36121 ttttcagttg ttcctctttg acgtccatac ttgaagaagt atggatctct tagataaccg
    36181 acatttttag gatagatatg aatctcttgc agttcctcgg ttgattctgt cgggtgataa
    36241 attggcaaaa tagcagcaat tgggatagct gtctgatcga tatcaacatc caatccaact
    36301 tctggatcaa tcgattcttc gaaaatcaaa taaactgcat cccgatcttg gtttttctta
    36361 ggtgctttga tacgtgcaat cccgtctcct aatccgccaa ccgtatcttt cccagttgtt
    36421 accgaagtcc ctatttggac aagcctttct tctgtgatta gctgacggat attgtttctg
    36481 ttcgtttcag cgatttgctg gacgaattct ttaggagtca tgttttcagc agcttttttt
    36541 tcatgataat aatcggtcat gtcgtaaatg gcaaatgtcg ctccatttag tggcaccgtc
    36601 tgtgaaatga tatctgctgt ttcccctgct tcctcagaga tagccaagcc atcattttca
    36661 tggtattcaa attgatcgtt ataatcgata tctcgaatca tccgtttatg caacacgaat
    36721 tccacgacat cttcccctga ttcttctgcc gacatcgcat gtggaagaag gactgctgca
    36781 agcggtagta aaacaagtaa ttgaagcatc aaacacaaca gctttttcat taccttgctc
    36841 cctccttttt agattgtctg acaaacaaac cataggctgc tcctgcaagc gccatgaaga
    36901 atgcagcaag caggatatag aataatcgtc cggatcctcc tgtagcaggc aacggatttt
    36961 caggatcgtt cccgacacta agctgtaatc tgattcgatt tgtctccaaa agttcatatt
    37021 ctaactcttg ctgtagatca ggcgtctctg cttcttcgtt tggataatac gaaatctcaa
    37081 cttttagtgt acccgcttct tttcctggaa ctacccgatc attttctatg tcaggttctt
    37141 ctcgataact aatttctaaa ataaagtaac ctggaagttt tctatagctg tcaggtgact
    37201 tcacttcctt gatccgatag accccttcca acaagtctga agcattgaat agggaagaat
    37261 cgtttggatc tggtgccaag cctccctcga tgatttcata ctctcctgca ctattttgtt
    37321 tctcaattga aaattctgcg ccttcaagac gtcggctatt catactgtca attttcaaaa
    37381 gttccaaatc gattggcgct agttcatctt ctaaggttac ttgtagtaca ccatcgatga
    37441 tttcatagcc ttccggcaag ggagcagttt cgtcttcgat gaccgtatct tcaatgataa
    37501 acttaccttc ttcattcagt gcaaactgga acacttgatc agatagccga tacccatttg
    37561 gtgcgacaga ttccgagacc tcatattcac caatagacag atgcagaggt tggtcgtaat
    37621 ttaaatcgac atacttttct actcctacgg cacgagaata gaagtatccg atcccaggca
    37681 aacgtttcga ttcttctggt tctaacggat taccagtgta tgctcgatac agcgggaagg
    37741 aagaatcccc cactttcctg atatcgaaac ctgcaccatc taatgtatgg ccttcatggt
    37801 ctaattttct aactcggatc tcccgataat caaacgtatt gtaagcagtg aatgctaccc
    37861 ataaacgatc ctcttcatct gttgtatacg tgagatattg ccaattttct tcacctgttt
    37921 gcttgagttg gatagtccct atagcattat cgtaaagtcg caagatccat gtgtcatttt
    37981 catcaggttc tttgaaacct tctgggttct ggctctcaat gattttgtat tctgcatagt
    38041 tggtagtttc ttcactatcc ttataaacaa atgaatctgg ctctccgatt ggatgaataa
    38101 ctttctcacc atccacgatt acatatttcc cgtcttcatc tactgaatag aacgtgagtc
    38161 tccctttctc ttcctctact tcgttcacac cagaaagccc tttcgctact ggatatccga
    38221 tttccagtcc gttaccatct gtttcataaa gttcaaactc tgcgccattg attggcatat
    38281 tactgccttc aattagttta ttgatattca tgtggattgg cttgaattca tttcgcattt
    38341 ccagtttgac atacaactca tcatactctg tgccttctat gttaggctct tgtacaacag
    38401 aaagcttgtg atattctcct tcataatagg aattcggatc tttaccttcc ggtccgccga
    38461 ctctcgaacc agatgtatat tcatctacaa gctcgtagtg acctaacatc tcatcttcgt
    38521 tggctgcata ttttttgatt tggaattgat acgtctcatc tactaactga taacgtggtg
    38581 gtccagcgat ctctctgatc caaaatatgt cgctgactgc tccagtttca tctcctaaaa
    38641 tcggcatctt cgtttcaaag atcgctattc cgtccgtggt agttttactt gtttcgattg
    38701 gttcggcttc cccactctct ggattttggt catataatgc aaattcgact ccagccaacg
    38761 gctcgccatt ttgacccttc ttgctgactt ggaaattacg gcctttatgt tcgtaacgaa
    38821 tggaagaaga tgggaaatac atccgtccag tagtgatatc attctcataa tcctccaggt
    38881 tctgaatata ggccatattg ttcactgtgc aaaaatttcc gtcttgagct cccgcatcaa
    38941 gttttacttg gtacttgatc ctgaccattt ccccttcacc taaagaaatc ggagaaaatt
    39001 tataagcttg gttttcccgt ccgacatacg ttgtcggagt cgccactact tctggtgggg
    39061 cttgtccatg acgttcttca tcccatattt ctggctcttg gtacttcatg ccgttttctc
    39121 ctggatctag atggtaaaac tgaatatctg ccgatctgcc agctccaaat ggtgagacat
    39181 taaaaccagt ttcatcataa agtgtggctt gctggatcgt tctcttgaag gtagaagaga
    39241 tatcctccaa ggctgtaaca atgtcattct tgttgttcgc attgtaatat cgcggtgtta
    39301 cgccatcttc ttctaaatca gcaatatttt tcaatacatt tcgtccaata gcatctagtc
    39361 gttgtctccc gctaacgttt ccatcgattc ctaaaccaat ggagaagata cttggcgggt
    39421 tctcttgata cttgtttttc agccaatgat gataagcaac tgtgttgatc gcagatgact
    39481 tttcttgcga agtaggactg ccattcgtat tgttattaga agaaccatca ccaacccagt
    39541 gagtcgcttt attatctcct tcttttacct ctccataacg atagtgtaca tttacttcat
    39601 cttctggacg gttaaagtca gatgcatagg taactggatg agtaaaccct gcattagaag
    39661 tattcccaga aaactcctca aaatttctga acaaaacgtc attatcttca gcaatcttat
    39721 cttccatcac agtccagttg ctccaagctc cattagtgct cgtacgataa cttgactgaa
    39781 tcggtgcata actgaaggtc ggtgtcccat ctcccacaac gattaggatt ttttctggat
    39841 ttctattttc tccgccattg tctttataca atgtttcata gccattttta agccctagtg
    39901 taagcggagt tcctccgatt ggtgtacgat ttaatgctgt attctcactt cccgtcaaac
    39961 gattgatatc atttgtcaat ggaaagatgt ccgaactgat ttgctcatgg ttattgatag
    40021 ctgtactatt atggtaaaaa ttcaccatac cgattcgaat atccagactc gggtcagaga
    40081 gcagatcttt actcatttcg tttactgcct caatcaacgc agcattttta gtttgactat
    40141 tggtcccagc ggttaattca ctcatactcg ctgacttatc tagaacaaaa acgatatcga
    40201 ttggactgat ttcctttttc tcgcccccga tgacatctag atagacattg taaagggttg
    40261 ttgcatcttc aggatgtaga tcagatgctg tgctgcttgg cagaacaggt tctacccatt
    40321 ttttgatgta cgccccgtta taatccaagt aactgttttc aaaattccgt tcatttcccc
    40381 aaagctgaac ggtttgagct ggaacgtttc tatcttcttc gcctgcagtt gatccattat
    40441 tagtagcata gtcgtaattt cgccagttcg ctcccccgtt tgtataatca ctatcatcga
    40501 tcaagttctc tccgtcatat ggcgagcctt tgtctccttg atagcgttca ttgctttgtg
    40561 tccaatttcc taacactttt gtatagtcat tcgttgtaaa cttcatctat tctttcatca
    40621 accaccactt gaagaggtag ttacccttcg ttcacatcgg ggatcttttc tgtttcaaaa
    40681 atcaatgtgc cggtttctgc ttcttttgaa taaacttttc cgacatacca ttcttgacca
    40741 tcgatcgtct cgacttttag gtcttctcca tcttcatcat aggaggatag acctgttcca
    40801 cgaacgtttt ttacggtacc aatcccggcg gctgccgcat cgattgctaa acgtattcta
    40861 ccttcattgg cactttcctt tttttcaaaa gccagatgcc attcaagggt ttcttctttt
    40921 tcaatatact tcccttcaat ttttgcatag tcctcatcta agaatacctc atcctccttt
    40981 gtttctgttg actcagcagc tacatccagg gtcgtcatat gatagactga ctggaaatat
    41041 ggtccaaata gcaaactgac agttactaac tgcaaaagct tcaattttaa ccctttcaca
    41101 tccttatact cctttcaaaa atatttgtct tctttcacaa caatcaacaa aacaatgccc
    41161 atctaattat aatttaattt aattttaatt ttaaatcaaa tgatatcctt tttagttaaa
    41221 aacaccaatt atacaacatt tattattaaa attaaattat aaaattttat aacgttctca
    41281 tttaacaaaa cttaagttat taagacaaat gaataaacaa ctacgctttc ctcgaaacaa
    41341 aaaaataaag cacaaatgcg catttacgca ctcatgcttt attcgtacaa ttaattcaga
    41401 taacggcagc gcataggatg ccaataacac ttcctaaaat agctcctcct aaaatgtcag
    41461 taggataatg taaaagtaaa aaaatcctcg aataagcgat caaacaagca aataaaaagg
    41521 ctaatattcc tgcaactgga cttaattcga acaacgcagc tactgataaa aaggctagcg
    41581 ctgtatgtcc tgaaggaaaa gaagaagtct tcggtttact tgtgtaaagg acaagccgac
    41641 gatttttttc ataaggtctt ttccgtcttg tcgttttttt gataaaaagc aaaccaacaa
    41701 aaaaatagat caaactgccg ataagaatgg ctagaccata ttctctagta tcaggtatca
    41761 agactaaaac agcagcaagg agcaaccaaa taaaaccacc attagagata ttactgataa
    41821 atttcaaaaa attgattttt cgactatccg ttttccgttg cttggcgaac ttgttgataa
    41881 tactatcatc gattttagca atcaaacgca acatgttatt cctccttttt aagaaccttt
    41941 tcttgcgtac gatggataaa aagcaggact tgaaaataaa acaagaaact gaaacctaat
    42001 aaagcaaaat agattggtcc tgcaaaccag aatgcgacaa gaaggatcaa cgtgcctgcc
    42061 aaatagaaaa gcgcgctttt gaaatcatta aaaaacaaga aaaatgcagt aatccaagaa
    42121 gcttcttttt gttccagttg aagcaagatt ttgtaactaa agagaagcgc gcttaataga
    42181 agcaaaaaca acgtagtata catcaatgta tagccaattc ccccacccca atagcggaaa
    42241 atctgataat cgatcaatag aagaagaaaa taaacacttg ctaaactatc ttgctttcca
    42301 taaagagaga agttctcacg aaactttttc cagaatagtg aaccgagctt tttctcttca
    42361 ttttttttgt aatgataaat catatacaga actgttcgac ttgcagttcc taatgtgaaa
    42421 acaggcaaga cgcacaggaa ccatagtagc tgtaaatgga taagacgtgg aatccattca
    42481 atgatttcta agaaataatc attggctttt ttaccaatcg atcgattcat catccttttg
    42541 aacctcctgt caaatccatc ccttcaatga aataacgttg tgcaaaaaag aacagcaaaa
    42601 tcgtcgggat caagacaagt gttgctcctg ccatcagata attccattgt gtcgttgctt
    42661 ggttctgaaa aacttgcaag ccaatctgta acgtgtattt ttcttgatct tggatatata
    42721 acagaggacc taagaaatca ttccaagctg cgttgaagga attgatcgca atggtaatca
    42781 aggcaggttt cgtcaatgga agcatcaaat gactccaaat atacaaatga ttcgctccgt
    42841 cgatttcagc agcttcgatc aattcattat tgatcgataa gtaaaattga cgcatcagaa
    42901 atatattgaa cgcattgccg aagaacgatg gaacgatcag gggcaaataa gtacctaccc
    42961 agccgatctt ggagaataat acatattgag ggatcatcgt tacaaacccc gggatcatca
    43021 tcgtagaaag aaccaaagca aacatcagct ttttcccagg aaaatcaagc ttcgcaaatc
    43081 cataagcaat aaaagaattt gaaaggacat taccgatcac tactagcaca gtgatgaata
    43141 atgtatttct tgcatagcgc caaaaaggaa aggcggcaat cgtatccaga tagttttccc
    43201 atacgatttt ttctgggaaa aaggtcggag gataacgaac gatttcttcc attggtttca
    43261 atgaagtaaa caccatccaa agcaatggaa tgatcaaaat gattcctatt actgtcatga
    43321 ggacataact tagtattttt tttgtttgcc gattcacact ggtctttttg aaataatcca
    43381 tcatttgccg tcacctccag aataatagac ccacttaggt gcaagcttca aattgacaaa
    43441 cgtcagaacc aacacgatca gaaacaggat cattgacata gccatcgcat aacccatatc
    43501 aaaagctacg aacgccttgt tccacatatg cagattataa aaaagcaaag aatttgcagg
    43561 tccgcctgtt ccatttttcg tcatgacata agcttcttga aaaatttgga aagaaccgat
    43621 cgtagaggtg atcacatcgt aaaaaataat aggagtgatt aatggcaaag taatactttt
    43681 gaactttccc caaacgcctg ctccatcgat ttctgctgat tcatataaag atctaggaac
    43741 attttgtaat gtagctaagt aaagtagcat tgctcctcca gaactccata ttttcatcaa
    43801 aatcaacgca ggtttcgtcc attgtggatc aaacagccaa gctggtccag ggatatggaa
    43861 ccagcccaga aatgtgttga tcaatcctgc agatggagaa agcagctgca tccataagat
    43921 gtagactgct actcctgata agactgccgg taaatagaaa gctgtacgga atacactgat
    43981 tcctttgatt ttttgattga gtactgtggc taaaaacaca ctgaaaatcg tcgtcagcgg
    44041 tacattgaag atgacgaaat aaacggtgtt gtataacgat ttccaaaata aatcatcgtg
    44101 aacgaacatt cttttgaaat ttgctagacc aatgaaattc atcttggatg tcaaattata
    44161 atcggtgaaa ctaccaataa ctgaaaaaag cataggccct agcataaata ccaagaaccc
    44221 gataataaaa ggcgagataa ataaataggc ccatcttgct tcttttttct ttcggataga
    44281 taaacgcttc aaattttctt gcctcctctg tacctagaca gtcaaaaatg gattattgat
    44341 tttgcttgac taagttttct actgcttttt gtgcatctgc caatccttct tttggtgatt
    44401 ttgttcctaa aagaatctgg tcaatctgtt cattcactaa tgtcgtgtaa tccggagcat
    44461 ctaaaggaac tggtgtgatc accgtatttt taaagttttc gtccgccatt tgatagatca
    44521 tttttccttt atccgttagg ttgtcattat tcactaaatt ctcattggct gtcttgctcg
    44581 ccatgatatc aaaacttttt tcgccgaatt tttcttgtac ttctggagaa gaaagatatt
    44641 tgatgaattc ataagaggcc tcaggatctt ttgctccgta tggtacttcc aagacgaatc
    44701 cgccacccca cgaccaatgg cctgaacctt cttctttttc tgggagctgc atcacgccaa
    44761 aatcaaaatc atccggtgca ttttccatca aactagagta ataattgata ttttgggcac
    44821 gcatggctac taatccggaa ataaatggat cagatacacc agacccaaat tcggcttcta
    44881 atttattgat cgtatttttc ccataataat cttgccagtc ttggatccac tccaaggctt
    44941 ccactttatt tttagtatca atcttgactt tttcatcttt gtcaaaccaa ctagtcccgt
    45001 tatctgcgtt tagcgcccat acatcagccc ctaaattcca taatggataa aaaccgatgc
    45061 gtgtaaattc ttttccttct tttttatcta gtttacgtgc tgtttcttct aattcatccc
    45121 aagttgtcgg tagatcttgt tcactgattc cagcttcttt aaataacttt ttattataaa
    45181 aaatgacttg tgtatctgta ttgaatggga tcgcataagg atcaccttca tattctactg
    45241 tatcccaaag ctgcggataa aaatccttag aagtgtcttt ttctacatat ttggagagat
    45301 tagttgcttg ctgtgcttct gctctttggg caacggaatt tatgtcctgt acaataacat
    45361 cgggtgcatt tccagctgtt attgcagata aagatttagt ccagatgtca ccccatggct
    45421 gatacttata atttacatgg atctcgtttt gtgattgatt gaaatcctca atgatttctt
    45481 cgatagcttc ttttcgtgca ccggatcccc aaaaggacca gaaatcaata ttttttcttc
    45541 catcacttgt tttttcagaa gaatttgctg cacttgaact ggcatcgctt gcattacttg
    45601 atccgcatcc tcctaataaa aacaatgctg aacttgccag caaccctgta aacaataatt
    45661 ttttcatatt ttacctccaa attttaatgt aaccgatgcc ggttttaata taacgatatc
    45721 attttgttct gaaaataaca atttataagg tatgattcta aaaaaattat taatgatacc
    45781 aatactttat ataattcgcg agcgctttct ttgaattttt taatctttcg tagcagaatg
    45841 agaatgtatt aaaaatagat taggaggaat tttgatgttt agacaccaga aagaattgca
    45901 gtttgaagca aaaccagatc gtccgaatcc attaatcgcg aaatatctgc aggagctgat
    45961 cggcggccaa tatggcgaga tgagtgtagc tatgcagtac ctgttccaag gctggagctg
    46021 ccgaggagaa gaaaaatata aagatatgct gatggacatt gcaacagaag aaatcggcca
    46081 cgtggaaatg ttggcgacaa tggttgctcg tttattagag ggtgcgcctg ttgaagatca
    46141 agaagcagcg atgcaaaaag atccaacaat cggtgccatt atctctggaa tgaatccaca
    46201 gcacgcgatc gtagctggct taggacctcg tcctgctgac agcgtgggca atccatggag
    46261 cggtgcctat atcattgcga gtggcaactt gttagcagac tttagagcta atttaaatgc
    46321 cgaatcacaa ggaagacttc aagtagcacg tatttacgaa atgatcgatg atcgtggcgt
    46381 aaaagatatg ctgtctgttc tccttgcaag agatagctat catcaaaatc tatgggaatg
    46441 tgcagtgaaa gaattagaag aaaaagaagg ttcaatctta gtcccaagta ctttcccgcg
    46501 tgacaaagaa cgaaaagaca ttgcttatga cttctataac ttctcagagg gagaccaaag
    46561 tagtgaaggt tcttgggcta gtggcaaagc actggatggc gaaggcgaat atcaatggtt
    46621 gaaagaacct aagatcgaag gcgctgcacc aaaattagaa ccagtaacac caaaaatgta
    46681 tgggacacct ccattcaaga aataaatatc tacccgtaga aacacccgtt ttttgttcca
    46741 cacgctttgt gagcaaaact gactaaagtc attaatcata accacccttc aaaagggtgg
    46801 ttttctctag agctataagc tcaaatcacc ggccagcgcc taaagacgct ggctttcata
    46861 ttttatgttc aagccatatt gcctttgcca gttttgccca cctcttaaaa ggtttatgta
    46921 ctactcctta gcccttaaaa ggatcgtctt actctcgtac actcagctta tctaacgcac
    46981 tatcatgttt ttcttgttct tgaatgtact ttttgatggt cgcttcattt tgtcctactt
    47041 ttgtcacata gtatccttcc acccaaaagt gtcgataccc aaatttatat tttagatttg
    47101 cacaatctct tgatgatctc ctgaatattg gctcgatatt gattataaat tatttttctt
    47161 ctatactttg gtgtgaatac aatgtggtat ttacacatct actttgtacg ggctaaacta
    47221 tttcccttta ttgctccacc cgcatagcaa gtggttttgt atttcaatcg ctcggcgcgc
    47281 tcaattaggt ctaaagacaa taaatctaaa aacccgctgc ttcactgaca gaaacaacgg
    47341 gttttcagaa aaaaatgaaa tgaaaaagat ctcttacggc aatctatttt atttttttga
    47401 ttttttataa atggaaaatg cttcaagaag tccaagaaat aaagccgtat aaaaacaaga
    47461 acctatgaaa tctttattta ttagatattc aacagaaatc ccgataacac tagccaacaa
    47521 tatatttatc agaagtgtaa aataaggatg ctttttatag aatagaacta gtgttgtttt
    47581 catagactct cctttcttca tatttccaat taatcacaaa ttcacggcat tactagaaaa
    47641 attaaagggg cgcagaagtg gaaaaatact cttcgacttt ccctacaaac caggccatct
    47701 tgtgtttaat aactatacca aatctaaggt acctctaaat ctaaattcca tttgtggcgg
    47761 tgacctccaa tttttaactc ttctatctcc catccagtat acataacctt gatacttcga
    47821 ccacttatat atcgaacaca caaataccta tccattgcag gagtactacc taacttagtt
    47881 gctacttgca tctaaataac agctgaaaag ataggactta ctcttagtaa agtatctgaa
    47941 ctattaattt ttaaactatc atttttatcc tcaactacat gcacatctgt tgcaacttca
    48001 ctttctgtct catccagata aatgattaag gaatcgggaa ttgcaatatc ttcagctgac
    48061 gctggaatag ttgagctaaa ttagtcatca tatctttatt ataaaataac caacagcaaa
    48121 aaatacaatg aaaaacaaac ttggaactaa tgtatcatta ataaatgttg aaaaattcag
    48181 caactcatta ctgtatgatt ttagcagccc aaccaacata taccctataa aagctaataa
    48241 gatggttagg aatcctttag aatttttact cattcataga cacttcctta aataactttt
    48301 attatagaag gtattgtaaa taataatatt gacaaaaagt gactcaaaat aaaaaaaaac
    48361 ttacattata ctggaatgaa ctgtattgat agtgtaccta aaagctctac tgacataaga
    48421 tcgtgtaatc ggtaaagtaa ttttattaat tatacgggat gtaatcaatt agagaataaa
    48481 ctaatcataa aaggtacttt tacattcata attgtcgctt tgagattcta ctttggttca
    48541 ctatctgacc caattgcaca ttttcgatca ttacaagtat tggtgtcgtt agaacaacta
    48601 aataaaaact agcggtagat ttttcagaat ctatgctaat ttctgtatgg atgttccagt
    48661 gatggcaaat ttctcttttc attgtttttc ttgtcgcatg atatgccttt ttgtgttatt
    48721 cagttaaact atagaaattc tttcctagac agatcttgat cccaaatttt acgtttttga
    48781 gcatcgatat agtttaaaat gacattactc atatctaaag agtttagatt ttttaggact
    48841 aaaactgtca gttgttcttt ttcttctttc tgttaaagta ttgtcgcgac ttttcgtata
    48901 cgttaagata tgtcgtgaaa aaacaagttt tgtgacacaa aaaaacgaat gacttgagga
    48961 aatcacctca atcattcgtt taaaatgcta tatattcttt agtttaagat acggaaatta
    49021 atgccatcga ccacactagt agaatgaacg acatttactt ggcctttttt taatttcgtt
    49081 atgtttagca tataaaaata ttatagagtt tacttacaat gcttaaaaca tatactgtat
    49141 aatctgatca attttagcca tgtcttgcaa tggtaagttt tctatttttt tgagttttcg
    49201 ttccttaaaa tcaagagatt ttaattgtgt aataattact tgtcctttta tatctagctc
    49261 ttcaggtaat gagtaacgtg tcggtaaatt ctttatagtg gaagtaattg gacatatgac
    49321 cgaaaacatt gttttacggt taaattcata acgagagacg actagtcctg gtcgtctttt
    49381 ttgaatttct tttcctacgg agggatcaaa atcaatccat acaatatcac cttttttagg
    49441 aatataaatt ctttcttctg acactataaa atttctctcc cttcaggagt taaatcttcc
    49501 cattcgtctt tctcataata ctcggcctct tccccaccac taaatggatc ttcaattttt
    49561 ggaactaacg taattgttcc atcatcagaa tacacaacga tatattcttg gttttctgaa
    49621 ggtttctttc cgttatcaga aggtaaagtt accactacag aacttccttg taatctagat
    49681 tttgtaacaa gcattatcat cactccctta ataaaagtat actatataac actaagtaac
    49741 gcaaaattcc cctttgtaaa ctatctagaa aattgttttg tttaaagtat atcttattgg
    49801 atataaatag aaataaattg tagccagttc attttttctt taactaaaaa aataatccaa
    49861 gaaacattga acctatggat ccaaaagcta cccaaatact atagctaacc ccccgctacc
    49921 ttcaattttg cagataaaac gctttgggag aaaatttcaa agacaacagg ccatcctatc
    49981 atgcccgatt ataaacaaaa agctggctat tccttttgct ctgacaaatt tcaattggga
    50041 aagttcacga aactagcagg tgaagaagtt tcaactgttc ggatcaaaga atgcccgctt
    50101 caaatagaaa cattggttca acgaatttca actagacaag actttgctat tgtagaacgt
    50161 gagatcgtag ctatttttgt agaagaaggg attttacatg atccaactca tatcaatgtg
    50221 gataaatggc aacctcttat ctataaattc agagaatata caactgccaa ccagtcgtta
    50281 actttgaatt ttagattcca agaattcaaa gagtcataat gataaacatc gttaggtata
    50341 aataaaaaag actcgcagca cgagtaaaaa acaaatagaa gctatacatt agaaaggtcg
    50401 actgtgaccc tatagatgca gtatatgcag cttatgagca tttcttctgt tctctttgtt
    50461 tttgggatct gtgctgaagt ctttttcgtt ttttgccgct ctttctttga aaaatcgatt
    50521 atgttatacc ttctccatta ctaattcagg catctgctga gtaatgattt ttcgcgcaaa
    50581 agaaatatct gttacccaag gttcgatttg ttcttcagtc aagacaagcg gcattcggtc
    50641 atggattggt gcgactgtgc ggttaggttc agtagtcatt atgattgatt ctgccatttt
    50701 ttcatcctga tggctacgat aaaaaccgcc aatatacact attttttcct tatttgaaaa
    50761 cataaatttg tctttttctt cattccactc attgggaaaa cacaacgatt ttgcaaaaat
    50821 ggttgatgaa aggtcttttt ttcttctact gtctctgcac gggcattaat catcaattgt
    50881 ccttttttaa atccggtaaa tccccacttc atgatttccg gagtgaggat gttttcttcc
    50941 tcttttctta acgtcacaac aagatttgac ggaaaaactt ctccagctgc taattctgct
    51001 gcctgcttcg gttgtttcgt ctgggcttct cgataataat tctgaaggag ctctgactct
    51061 agatcaaaaa aataacgacc acacatccta atccctccca atcttttttt ctatcataca
    51121 ctgcaacaag aagttcgcac caacaaaacg ctttcaattt ttgtagaact aaaaaagttg
    51181 tgacaagtga caaactctcc agtgaatggt attctcctgc caactcctcg gtcacaagtc
    51241 acaatattca acaaacatga gaagctgctt tttgaaattg ttccttgtga ctcggagtga
    51301 aacggcaggc ttacgacctc tgggtaaacg gtgttcaaaa gccagtttct cggtattaag
    51361 ccaaatttat gcaaaaatgt agaaagctat tttcacaaaa tttttctta
//
LOCUS       DACGMI010000015        51362 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.015, whole genome shotgun sequence.
ACCESSION   DACGMI010000015 DACGMI010000000
VERSION     DACGMI010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.015"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            637..2412
                     /locus_tag="IXT46_000993"
     CDS             637..2412
                     /locus_tag="IXT46_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946923.1"
                     /translation="MSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGGNLN
                     PGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLTMGL
                     TEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQGGL
                     LSPVALKVLEQYKLDGTVLPTNLAADSQWGKLLSSASYQVTANWSATELKKGSIHYRL
                     YSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTNMYP
                     SFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQENV
                     TFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLSKIG
                     DTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTILVPK
                     QELTLVNVPDDFTFGNDLHKPLKTSYYEAKVDFSFDVRDTRLPSTSPWQLTGTLTSLF
                     KNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLLEVN
                     SSTNAQPGATYQGMVTWELTAGPTS"
     gene            2468..4027
                     /locus_tag="IXT46_000994"
     CDS             2468..4027
                     /locus_tag="IXT46_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4946924.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            4024..5388
                     /locus_tag="IXT46_000995"
     CDS             4024..5388
                     /locus_tag="IXT46_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4946925.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            5559..6629
                     /locus_tag="IXT46_000996"
     CDS             5559..6629
                     /locus_tag="IXT46_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4946926.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            6644..7312
                     /locus_tag="IXT46_000997"
     CDS             6644..7312
                     /locus_tag="IXT46_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4946927.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            7332..7910
                     /locus_tag="IXT46_000998"
     CDS             7332..7910
                     /locus_tag="IXT46_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4946928.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            8313..9224
                     /locus_tag="IXT46_000999"
     CDS             8313..9224
                     /locus_tag="IXT46_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4946929.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(9480..10397)
                     /locus_tag="IXT46_001000"
     CDS             complement(9480..10397)
                     /locus_tag="IXT46_001000"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAQ4946930.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            10599..11036
                     /gene="zapA"
                     /locus_tag="IXT46_001001"
     CDS             10599..11036
                     /gene="zapA"
                     /locus_tag="IXT46_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAQ4946931.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            11094..11642
                     /locus_tag="IXT46_001002"
     CDS             11094..11642
                     /locus_tag="IXT46_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAQ4946932.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            11757..14117
                     /locus_tag="IXT46_001003"
     CDS             11757..14117
                     /locus_tag="IXT46_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAQ4946933.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            14204..14518
                     /gene="trxA"
                     /locus_tag="IXT46_001004"
     CDS             14204..14518
                     /gene="trxA"
                     /locus_tag="IXT46_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAQ4946934.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            14700..16478
                     /gene="uvrC"
                     /locus_tag="IXT46_001005"
     CDS             14700..16478
                     /gene="uvrC"
                     /locus_tag="IXT46_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAQ4946935.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            16623..17522
                     /locus_tag="IXT46_001006"
     CDS             16623..17522
                     /locus_tag="IXT46_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4946936.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            17515..18777
                     /locus_tag="IXT46_001007"
     CDS             17515..18777
                     /locus_tag="IXT46_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4946937.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            18938..20836
                     /locus_tag="IXT46_001008"
     CDS             18938..20836
                     /locus_tag="IXT46_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAQ4946938.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(21135..21854)
                     /locus_tag="IXT46_001009"
     CDS             complement(21135..21854)
                     /locus_tag="IXT46_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAQ4946939.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            22191..22523
                     /locus_tag="IXT46_001010"
     CDS             22191..22523
                     /locus_tag="IXT46_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946940.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            22510..24513
                     /locus_tag="IXT46_001011"
     CDS             22510..24513
                     /locus_tag="IXT46_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAQ4946941.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            24532..25002
                     /locus_tag="IXT46_001012"
     CDS             24532..25002
                     /locus_tag="IXT46_001012"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAQ4946942.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            25023..25607
                     /locus_tag="IXT46_001013"
     CDS             25023..25607
                     /locus_tag="IXT46_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAQ4946943.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            25622..26608
                     /locus_tag="IXT46_001014"
     CDS             25622..26608
                     /locus_tag="IXT46_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAQ4946944.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            26598..26909
                     /locus_tag="IXT46_001015"
     CDS             26598..26909
                     /locus_tag="IXT46_001015"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAQ4946945.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            26931..28712
                     /locus_tag="IXT46_001016"
     CDS             26931..28712
                     /locus_tag="IXT46_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAQ4946946.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            28705..30081
                     /locus_tag="IXT46_001017"
     CDS             28705..30081
                     /locus_tag="IXT46_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAQ4946947.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            30088..30723
                     /locus_tag="IXT46_001018"
     CDS             30088..30723
                     /locus_tag="IXT46_001018"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAQ4946948.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            30753..32108
                     /locus_tag="IXT46_001019"
     CDS             30753..32108
                     /locus_tag="IXT46_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAQ4946949.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKITIHSKIALTVTGTLLLGGFVVFFFTERNGETLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(32300..33694)
                     /locus_tag="IXT46_001020"
     CDS             complement(32300..33694)
                     /locus_tag="IXT46_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAQ4946950.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQKLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQNKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            33786..34757
                     /locus_tag="IXT46_001021"
     CDS             33786..34757
                     /locus_tag="IXT46_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAQ4946951.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKDKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            34754..35535
                     /locus_tag="IXT46_001022"
                     /pseudo
     CDS             34754..35535
                     /locus_tag="IXT46_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
     gene            complement(35704..36075)
                     /locus_tag="IXT46_001023"
     CDS             complement(35704..36075)
                     /locus_tag="IXT46_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAQ4946952.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TTPSYYFVIDPDGYKIEVIRG"
     gene            36209..36652
                     /locus_tag="IXT46_001024"
     CDS             36209..36652
                     /locus_tag="IXT46_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAQ4946953.1"
                     /translation="MDKPIFGEKKQSANYQTRYAAYIVIERDKRIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(36695..37504)
                     /gene="yidA"
                     /locus_tag="IXT46_001025"
     CDS             complement(36695..37504)
                     /gene="yidA"
                     /locus_tag="IXT46_001025"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAQ4946954.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(37523..38890)
                     /locus_tag="IXT46_001026"
     CDS             complement(37523..38890)
                     /locus_tag="IXT46_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4946955.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHKVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(38874..39704)
                     /locus_tag="IXT46_001027"
     CDS             complement(38874..39704)
                     /locus_tag="IXT46_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAQ4946956.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            39867..40304
                     /locus_tag="IXT46_001028"
     CDS             39867..40304
                     /locus_tag="IXT46_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAQ4946957.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            40380..41000
                     /locus_tag="IXT46_001029"
     CDS             40380..41000
                     /locus_tag="IXT46_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAQ4946958.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     EKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            41189..41695
                     /locus_tag="IXT46_001030"
     CDS             41189..41695
                     /locus_tag="IXT46_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAQ4946959.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            41712..42611
                     /locus_tag="IXT46_001031"
     CDS             41712..42611
                     /locus_tag="IXT46_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAQ4946960.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKARR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            42698..43583
                     /locus_tag="IXT46_001032"
                     /pseudo
     CDS             42698..43583
                     /locus_tag="IXT46_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
     gene            complement(43775..43846)
                     /locus_tag="IXT46_001033"
     tRNA            complement(43775..43846)
                     /locus_tag="IXT46_001033"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(43811..43813),aa:Arg,seq:ccg)
     gene            43906..45240
                     /gene="rpoN"
                     /locus_tag="IXT46_001034"
     CDS             43906..45240
                     /gene="rpoN"
                     /locus_tag="IXT46_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAQ4946961.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            45443..46480
                     /locus_tag="IXT46_001035"
     CDS             45443..46480
                     /locus_tag="IXT46_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAQ4946962.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            46521..47522
                     /gene="gap"
                     /locus_tag="IXT46_001036"
     CDS             46521..47522
                     /gene="gap"
                     /locus_tag="IXT46_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAQ4946963.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            47632..48822
                     /locus_tag="IXT46_001037"
     CDS             47632..48822
                     /locus_tag="IXT46_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAQ4946964.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            48926..49681
                     /locus_tag="IXT46_001038"
     CDS             48926..49681
                     /locus_tag="IXT46_001038"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAQ4946965.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            49797..51095
                     /gene="eno"
                     /locus_tag="IXT46_001039"
     CDS             49797..51095
                     /gene="eno"
                     /locus_tag="IXT46_001039"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAQ4946966.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        17058 a         8955 c        10858 g        14491 t
ORIGIN      
        1 tttatctttt caccttcggc agaagctgtt ggagcaacgc ctcctgccat ttcttatgat
       61 ccatacacgt atgaaaatat cgtacctcca aatggtggac gtagtgcagt caatggcggg
      121 aagcttgtcc aactaactgg ggctaaccaa ttgcctaaat tgactgctac ttatttgaac
      181 gatggttcaa atgatccttg gaaaggtggc acggtccgtt ttcattggga aagccatgtg
      241 aaactaacaa atgtacttga tttggtgaat atcactgcac aaggatttgc atttgtggcg
      301 atcatcaatt tgccggaaca tgtatcaagc agtgatgtat taaaagcaat tgactggaac
      361 aacgcctact tgtatattgc cggtgccccc atcaaggtta ctagcggtag tttattatca
      421 gcaggaagcc ataccttgcg ttttgggatg gggtcgtggg atacaaatac tctattggca
      481 gatattattg ctattattac gcgaggcgaa ttcaacgtgg acgatatccc gcttcaattt
      541 gatgttacag ctaatgtcgc gaagatgaca gaaaacggag ataaatatga tacgagtcca
      601 aacaaaattt tgaccaaggg taaattacaa ccttctatgt ctaaaaaggc cgttttttct
      661 gttgattttt atgattcgaa taatattatc caagatcgta tgttcaattc gattttagct
      721 ccagctgcag gtagatttta tcctaaatta actggcggaa acttgaatcc aggagcatat
      781 gcattttctg caagtgcaga gataaatacg tggaatagtt acatctcaac aagtgattca
      841 acaggaaaat ataatacatt tgctgatacc acagaatacg tggatggaaa taaccagaac
      901 cttccaggct ctaccaatag tcggacattg acgatggggc tgactgaagg acgttttgat
      961 cagttgccat ttagtcgctt tgatcgcgta gtcaactatt ttacaggaaa aaacgttaca
     1021 caaggagcaa tactgactca tactccagca agcacaagtg gattgaatca gacagccaat
     1081 atcgtgtaca gtgggaaaga tgcgcaaggc ggattgcttt ctcctgttgc tttaaaggta
     1141 ttggagcagt acaagctaga cggaacggtt ttaccaacaa acttagcagc cgatagtcag
     1201 tggggaaagc tcctttcttc tgcatcgtac caagtcacgg ccaattggtc agcaactgaa
     1261 ctaaaaaagg gttcgatcca ttacaggctt tattcgaaag gaacccaaaa attagcgaca
     1321 ggatggacag atcaactttt ccaaacgatc caatcaaata acgggggtgt aaatacagct
     1381 acttctacac tacctgcatt ggcttcaggg caatattatt ttgattatcg cttggtggac
     1441 gatgtactta ctaacatgta tccgtctttt gcgtacaaat ggcagtctga acaagctgga
     1501 atcaccactc ttcctcaaat aacagtggct aattttccat ctgtgagtgc agatagtcag
     1561 ctaaaaaacc ttagcagaca acctgagaca ggagatcccc tgtctgctct atcaggagat
     1621 acgattcaag aaaatgtgac attcacgtta acaaaatctg gggatgcgat aaccgacaaa
     1681 aaaatcacga tctcacttcc tgaaaatact acttatatca atggttcctt aaaattaaat
     1741 ggtacaacta tcgcagatac cggcattcaa caaggagttt ctgtcccagc agatctattg
     1801 agcaaaatag gagataccat tcatcttact tacaactatc aattaaatac tgtagatact
     1861 tctgtacaat ccgtcagcat actgacaaag gcagctgtac tttccagcaa tattacatta
     1921 gcagatggtg ctaagcttcc taacccagtt gtccaaacat ctgctaaaac aattcttgtc
     1981 cccaaacaag aattaacatt agttaatgta ccagatgatt ttacatttgg taacgatctc
     2041 cacaaaccgt tgaagacaag ttattatgaa gcaaaagtcg atttttcttt tgatgtgcgg
     2101 gatactcggc ttccaagcac gtctccttgg caactgacag ggacattgac ttctttattt
     2161 aagaatgatc aaggtcaaga attaagcgga acaaaattat acttcaatca ttctggatca
     2221 aaacaattga ttcagcaagg tcaaaacacg ttgatttatg agagtgatgg aacagctaaa
     2281 ggagaggttc tcgttgactt tcccgatacc gatggtttac tcttagaggt aaatagcagt
     2341 acgaatgctc aacctggcgc aacgtatcaa ggcatggtca catgggaact gacagctggg
     2401 ccaaccagct aagtgattag aatttgtatg gatctgtgat aactgtcaca gatcctcttt
     2461 ttcaaggatg agaaggaaac ttctgctgtt aaaatcagaa atgcttggag gagtggactt
     2521 ggaacttttc agtttgcttg aaaaaaatga acaacggcaa atcaaacttt tccaactttt
     2581 attagaggaa aaaggagaga tttccgttaa taacgtactt acccgcttat cagttgatcg
     2641 ggctaccttg aaagaagatc tgttttattt acaagctaac ttggaaaata tcaaacaatt
     2701 ggaaattgtt atccaagaag ggaatatttt attaatcaga catggaaata tagcagcagt
     2761 cgatgtttat tatcattgct acttgcgcta ttctacaaaa tatcagatac ttctttatct
     2821 gttggaaaat ggctcatttg atcggcagaa acttgtcatg gaacttaata tcagttcggc
     2881 tactttgtct cgcagagtga aggaattaaa tgattcttta aatgagtttc atctgaaaat
     2941 aaaaagcggg cggctgaccg gtccagaaag tcaaatttgt tatttttatt tccaattatt
     3001 ttggtttgga cgtccttatc ttgaaaacaa aaaagaatac agtgatttat caggaaacac
     3061 ttttttagat ctgctgcaaa aagagtttag ttttactatt acagaagaag gacgattgaa
     3121 atttgaaata tggctttcca ttatgaagaa gcgaatgcgc tgtacgaaaa aatccaaacc
     3181 agattatagc aatcttcctg ttggattgtt tcaaacgaca caatttttat tggacctcca
     3241 tacatttttg acccgttact tctttcaata tgcctttcct tggaatcaaa atgaaacgtt
     3301 ggttttttat cttttcatga tcagtaactt tacattagat acacataact cgcatgtcca
     3361 ggagtttttg ataagcgaaa aatacaaaga cgacgtagta gctcaattga atcgaacgtt
     3421 taaacaatcg atagaagaat atttctcttt ttatgttttt ccagaagaga tttcgcaaaa
     3481 gattgcgttg acagtgatgc aaaatcacgc tcattttgcc tattttagag gatggatgaa
     3541 tatttttggc caagaaggat taaaacagcg gttaactgaa gtagaagata aacaattcct
     3601 ggttttatgt gaaagattgg tcagacaaac atttgctatt gttgatttta ctgaagtaga
     3661 cgaggaaaat gcccgctttg aattatttgc tcgctatgca tctattttgc ggacgctgat
     3721 caagcagtta gaattacgtc tgcaaattgc ttatgatctt ccttatgaaa ggctaatggc
     3781 ggatatcgtg aaagaaatca tccaggaaca attgctgaat acgatcaaat atgatttagt
     3841 cgaatacgag aaagaaaagc agtatgatat cattttgact agccaattga aagagtaccc
     3901 gtcacagaag tccgctaaag tttttgtatt cactagcaac gaatataatt atgatttccc
     3961 ctatttgaac caatttttaa aagaatgtta tttagaaaaa ttgaatttaa ggatgaataa
     4021 aacatgaaaa tcgtgatcat tggtgcttcc catgcaggca tcacagctgc cctaaatcta
     4081 agaaaacttc aaccgaaagc agaagtttta ctgatcgatg aagatcataa agatggacta
     4141 ggctatgttt caaatggaat caacctttat ttaaaaggaa agatacgtag tttagctgaa
     4201 gttgcccata acatgcggac tcttcaagaa agtggggcaa aactgatcac cgaatggaga
     4261 gtaactgaac ttgatccaga caaacatcag ctcatcctcg catccaaaga aggaaaaaac
     4321 gagaccataa cctatgataa attaatcgta gcaacaggtt cctctcctgt caccttgtat
     4381 aaacaaattg aagctgaaaa tgtctacacc tataaaaatc tagtgcaatc taagcaagta
     4441 cttgccgctt taaaagaagc aaaagaagta gtgatcttcg gtgctggtta tattggattg
     4501 gaattagcag atgctttgag aaataaagga tacattattc atctagttga ttatatgccg
     4561 aatgttttat caagatattt cgataaggat atgatcaaca gttttcaaaa tcagctgcaa
     4621 actaagcaaa tcaattttta tccaaatgaa ttcttgatcg attggaaaaa atcagaagag
     4681 aaagtagtat ccgtacaact tctatctcaa gcaataaagg cagatatggt cattttttct
     4741 gcccaaactc gtcctaatac gacattgtta aaagaaaaag tggctttgta tgaggatgag
     4801 actgtgatag tcaatgaata tctgcagaca agtgatccgg acatctatgc gattggagat
     4861 atcgtcccag tcagttttga caaaaataaa cggcatctct ttttaccttt agttactcga
     4921 gctgtacata tggcaagagc agtagcgcta actttgagtg gtcagccaac cgcttacgac
     4981 ctcagacaaa agataacagc agcagtcatt atagactact ttttaggaac tgtagggctg
     5041 acagaagatg aagcgccatt cttggaacaa aataccggtt cgtgttcagg agaatttgat
     5101 ctatttccac aatacgatga agaaaacaaa acagtaaatg caaagctgat ctaccatccg
     5161 gatacattag aaataattgg cggacagctg ataagccaag aattcttatt atcagatttg
     5221 aacctgcttg cggatatcgt gaaacacaaa actacgattc cacagctagc agttgaggat
     5281 tttggatttc tgtctgaaca cacctctcgt tttcactacc tcaatgagtt agcttttaaa
     5341 gtactagcta agagagcaaa tagcaataga gtagataaaa gactgtgaga aatatcacgg
     5401 tcttttattg tgtggggata taataaatat taatcaatcg agaataaaaa attcatataa
     5461 tgaaatagcg gaagaatttt ttgagcataa tattcgccaa aaatttatca agtgataaaa
     5521 ttgttgtata aaatgattat ttcaggagga ggagttaaat gtttttagca ttaaatgaaa
     5581 ttatgcattc aaagttacgt tatgcgttag ttgcaggggt gatgtttttg atcgcctacc
     5641 tggtattttt tttgactggg ttagcttatg gcttagctca agataatcga acagcagtcg
     5701 acaagtggga ggcagattcg attgtgcttt cgaaagatgc aaattcaaat ctagggatgt
     5761 ccatgattac taagaagata gcagaagaag tcgaaggtgg gaaagtggcg tatcttgccc
     5821 agacacctgg agtcgtgact agtaaagaca gtacagaaga aggaaaaatc aatgttagct
     5881 tcttcggtat cgataaaaat caattcatca tgcccaatct tgttgaagga aaagcttttg
     5941 ataacgatga tgaggcagta ggcgatatta gtttgaaaga agaatatggt ctagccgtag
     6001 gagatacagt taagttatct ggtagtgaca agacgtttaa actaactggc tttacggatc
     6061 atgccaaatt caatgtctca ccagttctct atacaaccat caatgcttac caagagatcc
     6121 gcttcgaaaa agaagataca agtgaaaatg cacggattaa cgcaatagtt gtcagaggta
     6181 aaatcagtaa tttacctgaa gatttagaac agatcaaaat ttctaaattc atcaatgaat
     6241 tacctggata taatgcgcaa gtattgactt ttggatttat gatcggattt ttgatcgtta
     6301 ttgcggctat tgtgatcggg attttcattt atgtactgac gatgcaaaag attaatatct
     6361 ttggtgtaat gaaagcacaa gggatcacag gaggatttat tgcgcgttct gtagtggcac
     6421 aaacattcat tttatcattt gttggtattc ttcttggtct attaggaaca gtgggaacat
     6481 cccttgttct acctgatgcg gttccattcc aaagcaattg gctgtttttt ggcgtcatta
     6541 gcttgttgat gctggtagta gctgtgttag gcgcactatt ttctgttcgg acaatcgtaa
     6601 aaatcgatcc gttgaaggca attggataag aaggaggaag agcatgaaag caatagaatt
     6661 taaagaagta gaaaaaagtt tccaagatgg cgaccaagta gttaaagcat tgaaagaaac
     6721 aaccatgagt atcgataaag gggaatttgt tgcaatcatc ggtccttctg gttcaggtaa
     6781 aagtactttt ttgactttgg caggcggatt gcagacgcct agcagtggct ctgtatttat
     6841 caatgatcaa gaattcagta atcaaaaaga aagtgaacgc gttaaactac gttttaaaga
     6901 aattggcttt attttgcaag cttccaatct ggttcctttt ctgacagtaa aaaagcagtt
     6961 attattagta gataagatca aacatgaaca tcgtcaaaaa gaagcaaaag aattatttga
     7021 gcagcttggc gtggataagt tgatcaacaa gtatccagaa gaactatctg gtggagaacg
     7081 gcaaagggtc gcaatcgctc gtgcattgta caatgatccg tccattattc tagcagatga
     7141 accaactgct agtttggatt cagaaaaggc acgagaagta gtcgatatct tggcaaaaga
     7201 atcaaaagac aaaaataaag caacgatcat ggttactcac gatacacggc tgattgacaa
     7261 atgcgataga atatttatga tggaagatgg tgtattgaaa gaaaaagaat aaccaaaaag
     7321 caggtggaaa aatggtccat cgatacaaca aagatacaca gcaaaaaatt ttgaaagaag
     7381 cgactgactt gtttatgtcc aagggatatc tcggcacttc aacaagagag atcgcacaaa
     7441 aagttgggat cacccaaccc aatctctatc attatttcgg tgataaagaa aaactatata
     7501 cggcagtttt agaaaaccac ttaaaagatg ttggaaaagc tttgagagaa atcgttcaaa
     7561 caagcgaaac gggatttcaa gtaaccttga caaaaatggc gcagtttttg attgagacac
     7621 atctggtcga tttgtttctg atgcttcacg atcttgaaag caatctttca aaggaaacaa
     7681 gagatcatct tttctttcta tggaagaaaa attatcgtga accttttgaa gaaatctttt
     7741 cagcaaacca atctgtgcta agaaatggga tttcaaaaga aatcgcagca aggcattttt
     7801 tcttagtgtt agcaccttac atcactcggt cgaaaagacc tgtggaagaa ccgctaaatg
     7861 tggcgcaatt gatcgattta tatttgaatg gtgtattagg agaagcgtaa agctgttata
     7921 tagggagaaa aatagttagg tgaagaagca agatatgacg aagatcgtta tatcttgttt
     7981 tttttatata ggtagttttt cataaataca aatttgttat tctctcatga ttatcagggt
     8041 atatttttat ttattatgtc ggtgttccag gaagtgtttt aatttaataa cgaagaaatt
     8101 aattgtttgt agaatgaagg aaactattta ttgggtagat gaatcaccac gaatagtcaa
     8161 aaggagattt caggatatgc caaaaatgaa aaaaatcatt ttagcagtaa tgttattttc
     8221 tacggttata tcttttacag cccctttttt gcgtacttaa gctgatttta agttttgacc
     8281 cttagtctgg atctacgagg tgagagtcaa gaatgaaaaa aataattgga gcttttgtat
     8341 ttgcaatcat tatcattatt atctgttttc aaatagatgt ttttggtcaa aaaaagatag
     8401 ttggacaaac ggtcagcagt acgaacagta cggttacaaa gacaaaggaa tcatttgatg
     8461 atacagaaca agagacatta atcaaaatcg gaaaaaatga ccgtacacta tatacagatg
     8521 actcgctaac taccccactt gcaactataa acggcggaga gctggcggag tttctttctg
     8581 aaacaaaaaa tgcttatcag atcaagacaa atgatggcta tactggatat ttagccctcg
     8641 aagatggaac caaagtcaca aagaatatac aaacaaaacc ggaagagcta tctgatgcag
     8701 tgattgtatt agatcctggg catggcggaa atgatactgg ggcattaagc aatgatgaac
     8761 aaacagaaga aaaagatata acattaagta cagccataaa agtaaaaaag gcgctagagg
     8821 atgctggagc aacggtttat ttgacccata ctacagatga attagtacag cttggagata
     8881 tatgcgacta cagtgaagaa aaaaaggcag atgtctttat cagtttacac gcagactcta
     8941 cggaatatgc gaatgaagca actggaatca cgacatatta ttactatgga caagaggaaa
     9001 cattagcaca gacaattgct gactccttca ctgatctgcc tctggattca agaggaatct
     9061 ccactgggaa ctatcaagtt cttcgagaaa atcttcaacc ttctatttta atcgagatgg
     9121 gttatatgaa taatgatagt gatttaaagg aattagtaac agacagttat cagcagcaga
     9181 ttgctgcaag tttgacacaa gcattgacca cttattttca gtaataaata agcccagcca
     9241 aacaaaaata gctcctcata tttttcgttt ggccgggctt attatcgcag atgcaagctt
     9301 ttgaacaccg tttaaggaag aggttgtgag cctgccgttt aactccgcgt cacaaggagc
     9361 aatttcaaaa aacagcttct catgtttgat gactattgtg acttgtgacc gaggagttgg
     9421 catgagaaca ccgtttattc ggaacaaggg actgtgacat gacttttgtc acagttccat
     9481 tattttttta gcagcttcaa agctttttct gtattggcaa aatgaagttt ggcatatttt
     9541 tcaagcatag gcatgccgcc tttctccaat agttttgccg ctacttggtc agatttcgtt
     9601 ccagctcctg atggaagggt gattccagct tcagctgatg ctttgtgtaa ctcttccaaa
     9661 aagctggcac gactgatgat agaagcagca gcaacagcta aatgatattg ttctccttta
     9721 gtaacgaagt acagtttttc ttgtaattga tttttttcta aacgcgcata ttttttaaaa
     9781 tttgcttccg gcgtaaactg atcgatcaaa atcgcttctg gtttttctgg ctcgattttt
     9841 tttagcagca aatggatcgc ttgattgtgc aaagcgactt tcatccgaac ggcattgtat
     9901 tttggttgga tctcattgta tttttctgga gataagacaa gcagtttata ggggatggtt
     9961 ttttttaaga tgtcagcaag ctggatgatt tggctatctt ttaactcttt tgaatctcta
    10021 acaccaagtt tacgtaattc tgcaagctga tcacgtttca cataagcagc acatactgtt
    10081 agcggaccaa aatagctgcc atttccgacc tcatcactac ctaaaacgga taattgactg
    10141 atattttttg gcaaagaaga ggctgttttt gctggcttgg cttgtttatc ctgtgcctcc
    10201 ccccatttat cagcttctat tgctgcattc gtaccttgaa acatcacttt tccggatgta
    10261 taagcggtaa tggtcgtccc gtcttttttt gcagcaaagc tagtataagg aatctgttta
    10321 tttaacaaat aagagcgata gtatgctttc atttgactaa gttggtcgtt tgttgctttg
    10381 ataatgacgt tgctcataaa attctcctcg tttttataca taaaactata ccgcaactca
    10441 cgacttttcg ttttctaaga gattgcgaga catagcattt ttttaaagtt tatcatataa
    10501 tagttaagta tgtgaaaaat atttgtggag aacggtgaaa gaaccaactt catggtacac
    10561 taaataaaac tttcatcaaa taggaggaaa tgattcgtat ggcgcacgaa aaaacacgct
    10621 acaaagcagt gattgccaac caaacatata ctattatcgg acgggaaacc aagcatcata
    10681 tggatatcgt aacgaagctg atcaatgaac agttagcaga attgaaacaa ttatcaccac
    10741 aaatggataa tgaacaagca gcaatcttga tggctgtcaa tgcgctttcg gatcaattga
    10801 agaaacaaga aagaatcttg gagctggaag aagaaacagc agaattaaag aaaaaaatga
    10861 tcaaatttac agagcttgaa aatcgtgtga aacgcattga agcaatcgag aacgaagctc
    10921 gggaagtatt gaaagaaaat ggtcaagcag atcataccat taaaaatcat gtggaagcac
    10981 aacagatttt aaacgagaaa cgaaaaggac aaattaaaca aaaatcttct aattaagatc
    11041 cttttatcaa aataagaaaa atttaaaaaa gttagaagag aaaggaacgt agcatgctga
    11101 gtttgctgat tttattttta ttgctaattg cgtttttttc tggagcacgt cgcgggtttg
    11161 ctttgcaaat catattcgcg attggatatg tattgtcatt tattgctgcc cagcattttt
    11221 acaaaccatt agcaagtcat ttggaattat acattccata cccagctgtc accccaacat
    11281 caaagttagc attttttgat caggtatttg cttttcacct agatgaagct ttttatgcag
    11341 gaactgcttt tctgattatt ttgctaattg gctggctgct tacccgattt gtgggggttt
    11401 ttgtccatgg attgacgtat gtgccgatct tgagacaggt agactggatt gcaggaggca
    11461 tcctgtcact aatcatggct tacgttacta tatttttgat tttgcagtta cttgcctttg
    11521 ttccattaga tgtggtccaa aatcaattcg gcgagcatag tttcgctcgt tttatcgttg
    11581 agagaacgcc atttcttacc aacaagatgt atgagctttg ggtaacgaat attttgaatt
    11641 aaggaaaata gtgctggaaa atatttcgtt ttttgtacag agtagtttat ttaagaaggc
    11701 tgcgtagcgt atgtccggca cagctctttt ttcatagtga aagataaggt gataaaatga
    11761 ataaccgaat ccttgaaaca ttggaatttg aaaaagtcaa acagatggtc agacaatttg
    11821 tagtgactgc acaaggaaaa gaagaactgg cagaattggt accagtgagt gagaaacaaa
    11881 cgatcacaaa ctggcttcaa gaaactgagg atggattgaa agtgcaacgt ctgcgaggcg
    11941 ggatccctat acctaaactt gaaaatatcc gtccccatat gaaacggatc gagatcggag
    12001 cagacttgaa tggagtggag cttgcacaag tttccagagt attgtctacg acaagcgaat
    12061 tgaatcgttt cattgatgat ctttctgaca gtgaaatcga atttgcacgt ttgtatatgt
    12121 gggcagatca gttagtcacg atccctgttt tgagccgccg tttaaaggaa gcaatcgatg
    12181 aagacggacg cgtgactgat gacgcttctc ctgagttaaa gagcataaga cagaacattc
    12241 ggcgaagtga acaagctgtt cgtgaacagt tagatgggat cgtccgtggg aaaaatgcaa
    12301 agtatttaag tgatgcgatc atcaccatgc gaaatgaccg ctacgttatc ccagtcaaac
    12361 aagaataccg cggtgtattt ggcggtgtag tccacgatca aagtgcttca ggacagactt
    12421 tatttattga accaaaacaa gtggtggatt tgaataatcg tttgcgtcaa taccaaatcg
    12481 ctgaacgaaa tgagattcaa cgtattttaa gtgaactttc tgctgaactt gttccccatc
    12541 gtcaagaaat catccacaat gcttatgtga ttggtaaaat ggatctgatg aatgcaaaag
    12601 cacgatttgg taaagaagta aaagccatcg tgccgggaat cagtgaagac aatcatgtcg
    12661 tcttgaaaca agcaagacat ccactgatcg atcaggaaaa agtagtttct aatgacatca
    12721 caatcggaaa agactatcaa gccatcgtca ttacaggacc taacacaggt gggaaaacga
    12781 tcacgttgaa gactttaggt ctgttacaac tgatggggca agcaggatta ccgattcctg
    12841 caggtgaaga aagtcaaatc ggtatttttg aggaagtatt tgcggatata ggagacgaac
    12901 agtcgattga gcaaagtcta tcgacctttt cttctcatat gacgaacact gtagatattt
    12961 tatcaaaagt caatgaaaaa agtctggtat tatttgacga gctcggtgca ggaacagatc
    13021 cgcaagaagg tgctgctcta gcaatcgcaa tcttagatga tcttggtaaa aagtctgctt
    13081 atgtgatggc aacaacgcat tatcctgaat tgaaagttta tggatacaat cgggcaaata
    13141 cgattaatgc cagcatggag ttcgatgtgg atacactaag tccaacgtat cgtttgctga
    13201 ttggcgttcc tggacgaagc aatgcgtttg aaatctctag ccgattaggt cttgatacag
    13261 aagttattga tgaagcgaag cagttgatga atgatgagag ccaagattta aacgaaatga
    13321 tcacagattt agagaatcgc cggaaaatgg cagagaccga atatctggaa atgcgtcatt
    13381 ttgtttctga ggcacaagaa cttcacgatg atttgaaaga agcttacagc tatttctttg
    13441 aagaacgtga aaaagaaatg gaaaaagcaa agaaaaaagc aaacgaagtc gtgtcagagg
    13501 cggaagaaaa agcagaaaaa atcattgctg atattcgtaa aatgcaacag cagattgggc
    13561 aaggaaatgt gaaagagcat cagttgatcg atgcaaagac ccaattagca aatctacatc
    13621 aagaagaaac tttgaagaaa aataaagtat tgaagaaggc gaaagaacaa aaaacgttga
    13681 aaccgggaga cgaagtgttg gttacgactt acggccaaag agggacgctt ttacgtaaaa
    13741 acgggaatca gtggcaagta gaaatcggta tattaaaaat gaatgtgtcc gaagacgagc
    13801 tgacgcctgt tgctcctcaa aaagagccga cacaacgagt tatccatgct gtacgatctg
    13861 aatctagtag tcacgtgccg aatcaattgg accttcgagg aaaacgatac gaagaagcgc
    13921 taagtgaggt agatcaatat ttggattctg ccattctagc tggttatcct caagtgacta
    13981 ttgtccacgg aaaaggaaca ggcgcacttc gcaagggaat tactgattat cttaaaaacc
    14041 atcggagcgt caaaagcttt gagtttgcac cggcaaacca aggcggaaat ggtgcgacaa
    14101 ttgttaaatt taagtaaagc ttactaaagg taagcagatg gttcgctatc caagtataga
    14161 aatgctatac taatcataga ttttaaaaat ggaggtcttt gatatgtcac aagtaattac
    14221 agataagaca tttaatgaag aaacagataa aggacttgta ttgattgatt tttgggcaac
    14281 ttggtgtggt ccatgtcgta tgcaagcacc gattttggat cagttggaac aagaatatga
    14341 tgaagaagaa ttcagaattg ctaaaatgga tgtggatgaa aatccagaaa ctcctcaaca
    14401 attcggtatc atgagcattc caacattaat gttgaaaaaa gatggtcaag tagtagaaaa
    14461 agctgttggt gttcattcaa aagaacaact acgtcaaatg atcgatcaat atttataaaa
    14521 acttacagca aaaataagct gagggtggga ctgaatccag ttccgtcctc ggtttttttg
    14581 cggttgagtt aaggttattc aaattaatat tttttgagta taattacgtt gtcaggctgg
    14641 attgtttttt tgacagacat gctataataa ctttaattga atatgaaggg gagtaccaga
    14701 tgaacgaacg aatcaaaaac aaattagctt tacttcctga tcagcccggc tgttacttga
    14761 tgaaagataa aaatggaacg atcatttatg tcggcaaagc caaaatatta aaaaatcgtg
    14821 tccgctcata ttttactggc agccataata cgaaaacgga acggcttgtt agtgaaatcg
    14881 aagactttga atacatcgtt acagaatcga atatcgaagc attgctctta gagatcaatc
    14941 tgataaagaa aaatgatcct aaatacaaca ttatgttaaa ggatgataaa acctatcctt
    15001 tccttaagat aacgaatgaa aaatatcccc gtttggtgat tactcgtaaa gtactaaaag
    15061 acaaagcact gtattttgga ccatatcccg atgtcggtgc ggcgaatgag acaaagaaga
    15121 tcctcgatcg attatttcct ctgagaaaat gcaaacctag tcagacgaag gagccttgtc
    15181 tttactatca tttgggacaa tgtctgtgtc cttattattt cgacgtagat ccgaaagtct
    15241 atacgaaaat cgttgatgaa gtgaaaaagt ttttaaacgg aggacacgaa aaaatcgagt
    15301 cagagatcca tcagaaaatg gaaaaagctg ctgaaaacat ggagtttgaa aaagctgcag
    15361 aataccgaga ccagatccgt gccattgaga caatcatgac tcgccaaaaa atgacaaata
    15421 ctgatttact ggatcgagat gtatttggtt atgcgattga caaaggatgg atgtgtgtcc
    15481 aagtgttttt cgtaagacaa ggaaagctaa ttgaacgaga tgtttcaatg tttcctttct
    15541 ataacgaagc agaagaagat ttcttgactt acctcggtca gttttatcag gaaaatgagc
    15601 atttcattcc taaagaagtc ttgattcctg atacgatcga caagcccagt gtagaagctt
    15661 tgttagctac gaaagtgctg caaccaaaac gaggagaaaa gaaaaaatta gttgaattgg
    15721 cgaataagaa tgcctcagtt gctttgaatg aacggtttga tctgattgcc agaaaacagg
    15781 aacggacgat cggagcagtt gaacgtttag gaaacgcgat gaatatcccg accccaatac
    15841 gtatcgagtc ttttgataac tctaatatca tggggacgaa tcctgtggct gcgatggtcg
    15901 tattcattga tggaaaaccg gcaagaaaag aatatcggaa atataaaata aaaacagtca
    15961 acggaccgga tgattatgca tcaatgagag aagtcatcta tcgcagatat tcacgagtga
    16021 ttcgcgaagg gttgccttta cctgatttga tcttgatcga tggaggaaaa ggacaagtag
    16081 atgtggcaaa agatgtctta gaaaatcaat taggaatcga tattcctatt gctggcatgg
    16141 caaaaaacga taaacataaa acaaatgagt tgctattcgg tatagatttg gctgtagtac
    16201 cgcttgagcg aaattcacca gagtttttct tactccagcg aatccaagat gaagtccatc
    16261 gattcgcaat cactttccat cggcagctac gcagtaaaaa cagttttgct tcccgattag
    16321 atgaaattga agggttagga ccaaaacgaa aaaaaatgct gcttaaagag ttcaaatcgt
    16381 tgaaaaatat cacagcagcc acgacagaag aattacaaga aatcggactg ccgaaaaatg
    16441 tcgcacaaaa cgtatttgat aaattacatc aggaatgagg aaagggcact ttacaaagaa
    16501 agtaaagtgt cctatcattt tatgtacaac aaaaagagcg tttacgtttt gttggtaaat
    16561 aataaatcgc ttacgtctgg tgtctaagga tatatgtgat ttcttgaaga aggagtgaag
    16621 aaatgttaga agtcaaggat cttgttaaaa cttttgggaa ctacacagct gtcgatcatg
    16681 tctctttcca aatccccgat ggaaaaatca tggggctaat tggccaaaac ggggctggga
    16741 agacaacgac ttttcgtttg atcttggatt ttttgacaca agaccaagga gaagtgttat
    16801 ggaatggcca tcatcttggg gagaaagatt atgatgtcat cggttatctt ccggaggaac
    16861 ggggacttta tccgaaagta acgattcaag accaactgct ttattttgca gaacttagag
    16921 ggaaatcaag aaaagagatt gaaccaaaaa tcgatttttg gatggaaaaa tttcaggtaa
    16981 aagggaaaaa gacggataaa gtaaaatctt tgtctaaagg aaatcagcaa aaagtccagc
    17041 tgatcgccac gttaatccat gaacctaaat tgatcatttt ggatgagcca ttcagcgggt
    17101 tagatccggt aaatgctgaa ttgctaaaag atggaatatt ggaattgaaa aaacatggtt
    17161 catgtgtcat tttttctagc cacaatatgg ataatgtaga aaaaatctgc gatcatttga
    17221 tcatgttgcg aaacggaaaa atggttttga atggaaaagt acatgagatt cgtgaatcat
    17281 ttggccgtac gaagttattc ttggaatctg gtttaagcca acaggaagta gaagaaatcg
    17341 aaggcgtgaa aaaagtgatc cttcatgaag acaatacgtt agagattacc ttagaagatc
    17401 ctgaagctgg gaaagaaatc tttactcgtg cgactcagtt cggctacatt cctatgttta
    17461 accagcaacc gccaactttg gaagagattt tcaaattgaa agcaggtgaa atcgatgcgt
    17521 aagttttgga ttattaccaa agatgtctat ttaaaaaatg ttaagtcgat ttctttcttg
    17581 atcatgatat tagtcccttt tatcatgctg ggtatcattt atgtagcagg aaactttgct
    17641 caacaaaata gtgatgtcaa taaaatcggc gtattggctg ataatgagca aatcagtcag
    17701 caaatgagcc aagtcaaaac agatgatttt gagttcaaag cagttgattc tgaagaaaaa
    17761 gcacaaaaag agctttcgga agaaaaaatc gatgcgtatt tagtagtctc aactgagaat
    17821 gataagataa atgggatgct ttatagcgaa aattcattag gacaaagtac acaactactg
    17881 atacaacaac aactgactgg cttgcaatcg atgcttcgag caagtcaatt aggcatttca
    17941 ccagaagaag tagctagctt gagccaacaa gcaagtttga ctcgacaaaa agtcaatttt
    18001 gattcaaaag gaaaaatgac agttggagaa gataactcga cagtccaata tgtcgtaagt
    18061 tatgtagcaa cgattgtctt gttcattatt attttgacgt atgcgcagat cattgcacaa
    18121 gagatcgctt ctgaaaaagg cacgcggatc atggaagtga tcctgtccag tacgactgca
    18181 caaaagcatt tttacggaaa actaacaggt gttttacttg ttgcattaac gcaaatggca
    18241 ttatacggta ttatttttgg tataggatac agtcaattca aagatatgga aatggtcaaa
    18301 aatatattag acggtatctc attggataac ttgattggac cattcttgtg gtattctctt
    18361 ctattcatga tctttggcat tttgattttt tctgttttag cagctttatg tggctctttg
    18421 gtcaacaaag cagaagatac agcaaaagca attttgccag tgacttatct atctctaggc
    18481 ggatatatgc ttggattgat actaggagct tcagatccaa acaatatcgt tattcggatc
    18541 acttcgtata ttccattctt atcttcatat attatgccgg ttcgcttagc aaatgagaca
    18601 gtcggtatgg gtggagcatt gatttccttg ttggtacttg tagccgtaac attcttattg
    18661 atgatcttgt ctgcaaacat gtacaaatcg aatgtactcg tgtatagcga aggcggatta
    18721 tggagttcat tgaaacaatc gatttcaatt atgagaaatg aacgaaaaaa agcataaaat
    18781 atagaaaaat atagaaggaa gctggacatt tattgttccc agcttctttt ttgtatagac
    18841 ctatttctat ttttttatta tattggatat atattcattg aaaatagagc ataacaactt
    18901 tataatgttg agtataccaa tttttggagg cgttttaatg gaccgctatt tagatttact
    18961 ttcagagaag ttccctacaa cggaagatgt catcacggaa atcatcaatc tcgaagcaat
    19021 tttgcagctt ccaaaaggaa cagagttatt tttgagcgat atacatggcg aatttcctgc
    19081 ttttgatcat attctgcgta tcggttcagg aaatcttaaa gaaaagatca aagacctttt
    19141 ctctgaacaa atgacggaaa cggagatcag ccaattcact atttttacgg cttatccaga
    19201 atatgtgttg acgactgatt ggtacaaaaa acaagataaa tcccagctga tccatcgttt
    19261 gatcgatctt ttacggttta cgacagtcaa atacactcga tcaaaagttc gaaaaggatt
    19321 gccgaaagaa tatagctata tcattgagga actcttgtat atcgatgatc gtatcaacgg
    19381 gaaaaaagac tatgtaaaaa aaatcattga acaacttgtc ttgatgaagg aagaagaaaa
    19441 atttttaaca aaacttgcgc agacgatcca aaaatctgtc atcgatcatt tgcatatcgt
    19501 gggtgatatt tttgatcgag gaactcaagc agccaaagta atggatcgaa tcatggattt
    19561 ttcctctgta gatatccagt gggggaatca tgatattttg tggattggtg cgtattgcgg
    19621 ctctgaggca tgtttattga cgcttttacg gattgccgca cgctacaact atttatttga
    19681 attagagaaa gaatatggat taaatttacg tccattattt tcttttgccc atcaaaccta
    19741 tcagaagaat ccagtattta cccctaaaaa caggaaagat ctatctgaaa gagagcaaga
    19801 agaattagaa aagatccatc aagcactttc tatcctccaa ttcaaatcag aacatcagtt
    19861 gttgaatcga cgacctgaat ttaaaatgga cgatcgtaaa ttgttggaaa aaatcaacta
    19921 tgaggaatca acgatcgttt tagaaggtca gctctatgag ttgaaaggga cttgttttca
    19981 aacgatccag ccagatgatc ctaaaaaatt cttggaagag gaacaaaaag tgatcgatag
    20041 tttgatgtat tcattccagc actcgttaag aatgcaaaaa cacatgacgt ttttgatcga
    20101 aaaaggggga atgtatctca cgaacaatca gcatgtactg ttccatggct gtatacctgt
    20161 agatgaaaag gggcagctct tagcatttga attagaccaa tcttatcgcg gaaaagaact
    20221 gctgggattt tttgaaaaac agataactga aagcgcaaaa gatttgactg caaatgaaga
    20281 tttggcgacc gatttgattt ggtatgcgtg gagcgggccg ttttcgcctt tattcggcaa
    20341 gagtaaaatg gcaacttttg agcgctattt tctcacagag cctcatacgc acgtcgaaaa
    20401 aagcaatccc tattatcact tgcgagatga agagtggttc agtgaaaaaa ttttggcaga
    20461 attcgatgca aaagaagaag gttcagcaat catcaatgga cacacgccag taaaagtaaa
    20521 aaaaggagag tcaccgatca aagcaaacgg aaaagcattt gttattgacg gaggtctatc
    20581 caaagcttat caaaaaacaa ccgggattgc tggctactca ttactatgca attcttacgg
    20641 tttccaaatc gtgacacatt atccgttctt gcctattgaa caacaatttg caaaaaaatc
    20701 tgatcaaacg aatgtaaaaa aagtgatcga gcagcagctc ccacgcaaac ttaatcggaa
    20761 tacgacaaaa ggaatggaat tacagcaaca gattactcaa ctccaaaggc tgttggatta
    20821 tcgaaaggac gattgagaaa aatgctagcc aacattgctc aatagactaa aaagcgactg
    20881 caacaaaagg cgtgtcgcag tctccttcgg aattagctca aaaaacggta aaatattaga
    20941 agctattttt ctgtttattt ctctaatact caggtcaggg cgctgatttc acgacctctt
    21001 ccttaaacgg tgttctcctg ccaactcctc ggtcacaagt cacaatatcc aacaaacatg
    21061 agaagctgtt ttttgaaatt gctccttgtg actcagagtt gaacggcagg ctcacgacct
    21121 aatcagaaaa acgattaaaa ttcattcaca aagaaatcga ataaacgctg ttcagatgaa
    21181 tctacacgat gagaaagttc cggatgccat tggacaccaa ggattttgtg catattatct
    21241 ttactttgga ctgcttcaat gagtccatcg ttggaaaagg cgatggcttt taacaaagga
    21301 gaaagatctt tgactgcctg atgatgatag gaattcacaa agtatgaatc agggagaagg
    21361 tcacttaata aactgtccga aacgattttg acttcgtgag ttgcaaactg cggggcagtg
    21421 ggctgttgtt cgtgttttac ggaccatttt ggatataatg aaagatcttg ataaagtgtt
    21481 ccctccaaca cgacattcaa tagttgaagt cctcggcaga ctgcaaaaat cggttttctt
    21541 tgtttcaatg cttccaagat caatgcctgt tcgaattggt ctcgttgaat atttgtttcc
    21601 gtcagttttg gatgagggtc ttccatgtaa agttgcggac taacatcctg accgcctgca
    21661 agaatgagtt tgtcgatttt ctcaattagt tgaggcgctg aatctggaga catgactggc
    21721 agaataagag gtaatccttg agcatctaaa actgcatcca caaatccctg cggtgtatag
    21781 cttacttgat ttccttggaa agtatctgtc gctcgaatca gttgattccc ggcaatgccg
    21841 atgattggtt tcatttttat tccccctaaa gtagactaat tgtaacaagg atttaaaaaa
    21901 atttaaacta tgtaagactt gcccctatac ttatctgttc ttgctgtgtt actatctgta
    21961 aagagaattt tcgtgtgaaa ttcatgacga tagttgaaaa tattgcttaa tttgttataa
    22021 taaaaagtaa gcagaaataa aaaggttggg cgtaagcttc aaggatctag ttcttcaagg
    22081 ggtgagaagg acattttatt gaaggggcct gcctatacta agttatcttt agaggtacat
    22141 actttcaatg aaaaaagaaa gcatgtacct cttttttaaa tcgaaaggaa gtgaagcaag
    22201 tgttagaagc tttggaacaa atccgaaaag cagaagaaga aaatgagaag cgtgctcgaa
    22261 ccctacggca gcagttgaag acctatgcag aagaaaaaga gcaagaattg gagataatcc
    22321 aaacgaacag tcggcaacag ctgaaacagt tggtagaaga aaaagaacaa ttcgaaaagc
    22381 aagaattaga aaaagaaaaa atgaaattga aagcagaagc agacaaggtg caagcaactt
    22441 tgaaagacca atatcaaaag catcagagtc aagcaatcgg tgcaatcatt gaaagggtga
    22501 aagaaactta tggccgtcac taagatggaa aaagtgaccc tcatttcaga taaaagaaat
    22561 caggagagga ttttacaagc agtacaagga atccaaaatg ttgaaatccg ggatctgtat
    22621 caaaatagaa caaacaacca gtgggtagaa aaatattttc cagataccac gattattgat
    22681 aaagaagcaa aattaagcgc tttaggcaat cggctgaaag acatccaaga agctatccaa
    22741 ttcatacaac accacggcga tagccgtcaa aagaaactcc atttgaaacg tcaagaactt
    22801 tccttacaag acttggaagc aaattattcc gaagaaaatt tcatgaataa attagaagaa
    22861 gtccttgatt taaaagaaaa gtgggaacag ctaactgaaa aacgtgatcg tttagaagaa
    22921 gaggaagaat ggcttcttca ttggcaacag ctggatattg ctccaagtat gtatgcaagt
    22981 aagacgacca tttttgagat ggggactgtg agtgcagcaa attttgaaag tttcaaggaa
    23041 gaactaagta agcttgatga cgtttatatg gaagaaatag attatacgcc aaaacaagtt
    23101 tatctttcgt atgttgcttt aaaaaaatca gttgctgcta tagaagaaat tgctgggaaa
    23161 tacgggttca ataaagaaac gtatccttat gaacaaaatc ctaaagaaaa attgcaagaa
    23221 accaaacagc aattatccat tgttcacgag cagcaaaaaa agataacgac agcgttaggt
    23281 cagtgcagcg gctatatcca agaatttgaa tgggtagaag aagtcacact tgccgttgca
    23341 gaacgggaaa aagtaaaaga acggtttatc catgccactt atctgatcgt tttgcaaggt
    23401 tgggtagatg cagaagaaaa acagaatttg atgcatgtgt taaacgaaac tgtatcagaa
    23461 gaagatatat acgttagttt cgaaacacca aactcagaag agattcagca ggaagtccct
    23521 actaaattga aaaaccatcc gcttatcgaa ccttttgaat tgctgactga aatgtacagt
    23581 ctgccaaaat atgaagaagt agatccaacg ccttggatga caccatttta tcttgtcttc
    23641 ttcgggatga tggtcgcaga tgttggttac ggattgctga tgctcattgg gacaatacta
    23701 gctcaaaaac tatttgtttt accccgcggg atgaaacgtt tcgtaaaatt ctttgagatt
    23761 ctctcggtac catcgatcat ctggggattg atctacagtt catttttcgg acaggcatta
    23821 ccaaaagaac tatttggtat ccgcttgcct ttcccaatcc tatctacgac ggatgacgtc
    23881 aatacgattt tgattttatc cgtgattttc ggtctgatac agatcttggt tggattattc
    23941 gtggcagcaa aggaaaatat caggaggaaa gattacttga gtgctgtcag tgatggtttt
    24001 gcctggcaag ggatcctgat tgggatcgtt attgcattga ttggtgtcat gttgataaaa
    24061 aatacagcat ttgtttatct tggcgcgggg ctatcgatca ttgctgcttt atgtatctta
    24121 atcgtgccga ttatccaatc gccgtctaaa gtcaagggtg ctgccaaagg agcgtataat
    24181 ctttacggat tgactggtta tatcggtgat ttagtcagtt atacacgttt gatggcacta
    24241 ggtatttcag gcggaagtat tggcgcggca ttcaatatgc tagttgcttt catgccgcca
    24301 gccgctcgat tcagtgtagg gatccttttg atcatcgctt tacacgcact gaatatgttt
    24361 ttgacactgt taagtgccta tgtccatggt gcacgattgc agtatgtcga attttttgga
    24421 aaattttata caggaggcgg acgtgccttt gacccgctga aaacggcgga aaaatacgtc
    24481 aacatcaatc ataagaaaaa aaacaataaa taattggagg atttttatac aatgatggat
    24541 tacttaatta gtcaaaatgg tggaatggta tttgcagtat tagcgatggc aacagcgacg
    24601 attttttcag ggattggttc agctaaaggt gttggaatga caggtgaggc agcagcagcg
    24661 ttaacaacaa gtcaacccga aaaattcgga caggctttga ttctgcaatt gcttccaggt
    24721 acgcaagggt tgtatggatt cgttatcgcc tttttgattt ttatcaactt aggaaatgat
    24781 atgtcagttg tacaaggatt gaactttcta ggcgcttctc tgccgattgc ttttacaggt
    24841 ttgttttcag gtatcgccca agggaaagtt gcagcagcag gtatccaaat tttagcgaaa
    24901 aaacctgaac atgctacaaa aggaatcatt tttgctgcga tggttgaaac atatgcgatt
    24961 ttaggtttcg ttatttcctt cctattagta ttgaatgcct aagcataaag gaggaaaagc
    25021 agatgaacgc cattgaaaaa atcatctctc agatgaatga agcagcagag caagaaagag
    25081 cggcgttaga gcaagaagag cgaatgaaga tcgatcaaaa ctttgaacaa aaacgtacgc
    25141 aaatcgaaac agaacatcaa aaacaaaaag aaaaacaaat cgaattactt gaaaaaaaat
    25201 accgtcagct taggaatcgc caacaagtag aagtacgaca agaaaatttg aatgcgaagc
    25261 aggaattttt acgacgattg tttgcagatg caatagctga aatggagaat tgggatgaat
    25321 ctgaacaaat ccagtttatc aaaaattcat tgtattcatt acctttgaca ggcaaagtaa
    25381 cattcattgc tggagaaaaa tcagcagctt atctttctca gacattgctg gatgaatgga
    25441 acaatgaact tccctttatg atggttttaa gtgatgaaac tgttgctgat caagcgggtt
    25501 ttctgataaa cgatcaagga gttcagtata attttctttt cagcagcctt gtacaagata
    25561 tccaaggaac gatgagtttt gagattgcca atcaattatt cgaataagga gggatcagtg
    25621 tatggaatac cacgaactaa atcccttgat tcgcggaaga gagcttgaac ttttgtccaa
    25681 tgagacattt gaacggatga ttcaaacaaa ttctgtcgaa gcacttggtg aaatattgaa
    25741 atccacgatt tacagtccat atatttatga cggatatgaa tatgacttcg aacagaatct
    25801 tttaaaggag cagagccgtc tatttcgctg gttaaaggaa tcagcaccgg agcctgaaat
    25861 cgtttggatc tatacgatgc gctatacttt ccataatctg aaggttttga caaaagccga
    25921 gatgacaaat caaaatctgg accatttgta tatcgacgat ggattttatt cattagaaac
    25981 cttgaaggat gccattcata cgcaagtttc aaatgaactc cctgaaagca ttatggacag
    26041 tatacgagaa gtacgtgatt attttgaaga gtctaccatt cttcagggaa ttgacgtgat
    26101 ttatgatcga cagtttttga cagagcagcg acggcttgcc gataagctag gatatcaaga
    26161 attgctgaca gaagtcattg cttttattga cttgaccaat atcacaacga tggctcgagg
    26221 aatattgcag aaaagaacat atgggttcat gacgacggta ctttccagct cgggaagtat
    26281 cgaaaaagaa gtatttttga actttgtaga taaagatatg gaagattaca cgaattttct
    26341 attagagaca gattatgctg attttctgcg ccctgtcatc cgtgagggaa atcttgatct
    26401 cgtaaagctt gaacagttga aagatgatta tctaagttca ttgtatcaag aagcacaaac
    26461 ccaggctttc ggaccactgc cactactagc ctttttgaac gcaaaagagg tagaaagcaa
    26521 aaaccttcgt ttactggtta tcggcaaaag aagccatttc gaaccagaaa caatcagaaa
    26581 gcgggtgaga caagtctatg acgcataaga tcggtgtagt tggcgacaaa gattctgttt
    26641 tgccattcaa attgtttggc tttgatgttc gttatggtac aaccaagcaa accgttcgtc
    26701 aggcaattga agaaatggca aagaatgagt atggcgtgat ttatgtcaca gagcaatgtg
    26761 cagcattgag cccagaaacg atcgaacgtt acaaggaaca aatgatacct gctatcgtat
    26821 tgattcccaa tcatcaagga tcattaggga tagggctgga agaaattcaa aaaaacgtag
    26881 aaaaagcagt aggtcaaaat atcttatagt atgaaaagga gatagaaatt ttgcaaattg
    26941 gaaaaatcat aaaagtctcc ggacctcttg taatggctga gaacatgtct gatgccagta
    27001 tccaagacat gtgtctagtg ggagatctag gagttatcgg agaaattatc gagatgcgtg
    27061 gcgatgtggc gtctattcaa gtatatgaag agacttctgg aattggtcca ggcgaaccgg
    27121 ttcgctctac tggtgaagct ttatctgttg aattaggacc agggatcatt tcacaaatgt
    27181 ttgacggaat ccaacggcca ttagatacct ttatggaaat cacacaaagt aatttcttag
    27241 ggcgcggagt tcaattgccc gcattggacc atgagaaaaa atggtggttc gaaccaacag
    27301 tagaagccgg agaaacggtg agtgctggag atgttatcgg gatcgtagaa gaaacaaaag
    27361 ttataaaaca taaaatcatg gtgccaaatg ggataaaagg tacgatcaaa acaatcgaaa
    27421 aaggttcatt cactattgat gaaacagtat gtgtcattga aaccgaaaat ggtgacaaaa
    27481 atttgacgat gcttcaaaaa tggccagtaa gacgtagtcg gccaatcaaa gaaaaattaa
    27541 acccggatgc acccatgatc actggacagc gagtgattga tacattcttc ccagtgacaa
    27601 aaggaggagc agcagctgta cctggtcctt ttggtgcagg gaaaacagtc gttcagcatc
    27661 aaattgcaaa atgggccgat gtggacatgg ttgtctatgt gggatgtggc gagcgtggaa
    27721 atgagatgac ggatgtttta aatgaattcc ctgaattgat tgaccctaat acaggagaat
    27781 cgttgatgga acgtacggta ttgattgcta atacatcaaa catgccagta gcagctcgag
    27841 aagcttctat ctatacggga atcacaattg cggaatattt ccgtgacatg ggttatgacg
    27901 ttgctatcat ggcagactcc acttcacgat gggcagaagc acttcgtgag atgagcggac
    27961 gtttggaaga aatgcctggt gatgaaggtt atccagctta tcttggttca cggcttgcgg
    28021 aatactatga acgatctgga agagtcattg cattaggatc agaaggtcgc gaaggaagta
    28081 taaccgcaat cagtgctgta tcgccgtctg gaggggatat ttcggaacca gtcacacaaa
    28141 atacattgcg ggtcgtaaaa gtattctggg gtcttgattc cagtttagcc caaaaaagac
    28201 attttccttc gatcgattgg atacaaagct attctcttta ttcaacagaa gtagggaagt
    28261 atatggatca tatccttcaa gctgactggg catccatggt caccgagggc atgcgtattt
    28321 tgcaggaaga acagcagctg aatgaaatcg tgcgtttggt agggattgat tccctttcag
    28381 ataatgaccg tctgacatta gaagtggcaa aatccattcg tgaagattat ttgcagcaaa
    28441 atgcttttga tgatgtcgat acattcactt caagagagaa acaattcaaa atgttgaaga
    28501 tgatcttgac ctttggtgaa gaaggacgcc gtgcgttgtc gttaggtgct tatttaagtg
    28561 agatcatgga cggtaccgta tcgattcgtg aaaggatcgg acgaagcaaa tatatcccgg
    28621 aaacagaatt agaaaaacta gatcaaatta ttggtgaaat caagcaaacg atgcaaacga
    28681 tcgtttcaga aggaggcatg agcaatgatt aaagaatatc gtacgatcgg tgaagtcgtc
    28741 ggtccattga tggcggttga aaaagttgct ggtgtcaaat atgaagaatt aatcgaagtc
    28801 cgtatgcaaa atggcgagat tcgtcgtgga caagtattgg aagtccaaga agataaagca
    28861 atggtccaaa tattcgaagg aacaagtggt atcaatttac gtgactcttc tgtacgattt
    28921 ttaggccatc ctttagaact aggtgtatcg gaagacatga tcggtcgagt attcgatggt
    28981 ttgggacgac cgaaagataa cggaccagag atcctgcctg aaaagcattt ggatattaac
    29041 ggagaagtaa tcaatccagt agctcgggat tatccagatg agtttatcca aacaggtatc
    29101 tctgcaatcg atcatttgaa tacattagtt cgtgggcaaa aattaccagt attttctggc
    29161 tctggtcttc ctcataaaga attagctgct cagatcgcgc gacaagcaac ggtactcgat
    29221 tcatcagatg atttcgccgt agtctttgct gctattggaa tcacttttga agaagcagaa
    29281 tttttcatgg aagattttcg tcaaacgggc gcaatcgacc gttctgtcat gtttatgaat
    29341 ttagcaaacg accctgcaat cgagcgtatc gctactcctc gtatggcttt gactgctgca
    29401 gaatatcttg cttatgaaaa gggaatgcat gttttggtta tcatgacaga catgaccaac
    29461 tatgcagagg cattgcgaga gatttctgca gcacggcgag aagttccagg aagaagagga
    29521 tatcctgggt atctttacac gaacttagct actttattcg aacgagcagg aagaatccgc
    29581 ggactaaaag gatcggttac tcaaattccg attctaacaa tgccagaaga cgataaaact
    29641 catccaatcc ctgacttgac tggttatatt acagaaggac agatcatctt gactagagag
    29701 ctttacaaga gtgggattca gccaccaatt gatgtactcc cgtctctttc gcggttaaaa
    29761 gataagggaa ctggacccgg aaagacaaga gaagaccatg cagctacgat gaatcagctt
    29821 tttgcagcct atgcacaagg aaaacaggca aaagaattgg ccgtagtttt aggtgaatct
    29881 gctttatctg atgtagacaa gatctatgcg aagtttgctg agcggtttga aaaagaatat
    29941 gtcaatcaag gattctacac gaaccgttcg attactgaaa cacttgatct agggtgggaa
    30001 ctgctatcga tgttgccaag aaccgaatta aaacgaatca aagacgacat gctggacaaa
    30061 tatctgccag aagggaagtg agttctgatg gcacgattga atgtgaatcc gacccgcatg
    30121 gaattgactc gattgaaaaa acagttgaca actgccacaa gagggcataa attattaaaa
    30181 gataagcaag atgaactgat gcgtcaattc atcctgttga ttcgaaagaa caaccagctg
    30241 cgtcaagaaa tggaagagtc tatgacagaa gcaatgtctg attttgtatt ggcaaatgct
    30301 tcgatcacgg agcctttcat cgaagaatta tttgttttgc cggcggaaaa cgttgatttg
    30361 tctatcgtag acaaaaatat catgagtgta aaagtacctg tgatgaattt tgaatatgat
    30421 gaacagctga cagacacacc tttggaatac gggtatttga attccagtgc cgaactggat
    30481 cggtcaatcg atcggtttac taccctgctt ccaaaacttt tggaactgac agaaatcgaa
    30541 aaaacttgtc aactgatggc gagtgaaatc gaaaagacac gtcggcgagt caatgcatta
    30601 gaatatatga cgatccctca attagaagaa acgatctatt atattcgtat gaagctggaa
    30661 gaaaacgagc gcgcagaagt aacaaggttg atcaaagtaa aaaatatggg taccactgac
    30721 taagtggtat ccttttttaa aagaggaaaa cgatgattaa acaaagcaaa caaataaaga
    30781 aacgcttgcc ggctgttcag cttctcgcat taggattttt tctcctgatt ttagttggcg
    30841 gcggcctact taccctacca ttttttagta atagtgggca tgggacaaat tttatcgatg
    30901 cgcttttcac tgcaacttct gctgtctgtg tgacgggatt gacaacattg aatacagcag
    30961 agcattggaa cagtgctggt caatttttga tcatgctttt gattgagatc ggcggtcttg
    31021 gttttatgat ggttccgatt ctatgctttg cattgataaa gaagaaagtc agtctcagca
    31081 cacgtattat attaaaagaa gcgctgaatc tagaagaagt atcaggtgtg atgaagctca
    31141 tgctttacat cctgaaattg gcctttgtga tccaactgat tggtacggtt gctttatctt
    31201 ttgtattcgt gcctgaattt ggctggttga aaggtatctg gtacagtttg ttccatgcaa
    31261 tctctagttt ttgtaatgca gggtttgatt tgttaggaga cagtttagcc aatcaccagc
    31321 aaaatgttta tttgatcatg gtggtatctg ctttgatcat ttctggtggg ttaggcttca
    31381 tcgtatggcg tgatttactg gaatatcatc agaaaaagaa gataacgatt cattcaaaaa
    31441 tcgcattaac cgttacaggt acccttttat taggcggatt cgttgtgttc tttttcacag
    31501 agcgcaatgg ggaaacgcta gtggaaggga atatgtttca acgattggca aacacctttt
    31561 ttatgagtgt gacacctaga acggctggat attattcagt tgattacctc catatgagcc
    31621 atgcaggtct gattttaacg atgtttttga tgtacatcgg tggaacatct gggtcgacgg
    31681 ccggcggatt gaaaacaact acgttaggtg tgttgctgat ccagatgcgt tcgatgctta
    31741 aaggacgtac gagagcggaa gcatttggcc gtaccatccg acaaggcgca gtgttgcggg
    31801 cacttacttt attttttgtt acgttgacgt tgtgtgtagt cgccatcatg attttatcgg
    31861 tgactgaaac gatacctaaa acttctggca tcgaatatat tgcttttgag gtcttctctg
    31921 cgtttggtac agtaggtctt acgatgggat tgacgccaga cttgactgca atagggaaat
    31981 tgatcattat agcgcttatg tacattggac gagttggtgt attgactgtg gtcttctctc
    32041 tgatgacaaa agcacaaaga acacaatcaa aatacaaata tccagaagaa agtgtcatga
    32101 ttggataatt tcatcttctg acagaaacct agtgatttag taaaataaga aaataaaata
    32161 atttttcttg cttcttggat actttaagtg caaaatgttc gtttattttt tgaggcacta
    32221 tccgttgttg aacctcgggt agtgcctctt tcttattgaa aggaatcaat aagatttgat
    32281 tcctttattt atcaataggt tataattcat atttttttat tttttctttt acgatactta
    32341 gtccagaagc taaaatttca aggttattag aggataggga aattcgaacg aatgcatctg
    32401 gttgcgcacg tgtagtaaag cgtctggaat gataaagtcg gataccgtta gcaagaaagt
    32461 cattctcaat tatcttagga tcaatctcag gatcaactgg aagaattcga tagtaaggga
    32521 cacgattcgt tggtttttct actttgaaaa gagaatcaaa aagctgattg gctcttttcg
    32581 taagacttaa tttagtttct aagatcctat ttgcttcatt tgaatggagg atttgagtga
    32641 tgacttccac atctaatcca gaagttttca catttatatt aaaaattgct tgttctatct
    32701 tgttttggac atgtactgga actacaagat aagcaactcg caatccagaa caaataaatt
    32761 ttgtcattcc agctaagtag attgtttggt taggtaataa tttttggaaa ggaggaatga
    32821 tcgtatgttg atagtaagtt gttaaaaatg aatggatatc atcttcaata acccatagac
    32881 cttctttttc aatcacttcg gctaattgct ctcgtctttt gtgagagatt tgaaacccta
    32941 taggattatt acaagaaggc ataagaaaga caccatgaat cttctttttt ctacattcct
    33001 gaatcaatat atcaggtcgc attccttgct cgtcaaaatc aattggaacg atctctaaat
    33061 gatataactg agccaattca atgaaattag cgtatgtata tcggtctgtt gctattctat
    33121 cacctggaga gaaaagtgca gaaagtgtga tagccaatcc attttgaaca ccggaaacaa
    33181 tagatagaga ttctaaggac ggaatgactc cttgagtttt taaccaattt gctgcagtag
    33241 tcaattgaaa atttgtgcct ttgggatctt ggtaattaag caaaccaaca agatttgggt
    33301 tattactagt tgattgaata aacgggacaa cgaatttatt acattcttca aaagaactaa
    33361 ccagaccaaa atcaatgata tgttcggtta cttcattggt agagatggtg atggactcaa
    33421 agacattggg agaaataaat gtgccacttc caatattcgt atacagcaaa cctttctcaa
    33481 ttccatattt ataagccttg ccaacggtag taaaatttaa atctaaataa tcagctagct
    33541 ctctttggga gggtaactga gtgtttttct gtaatttatt ctttaaaata tcttgttcta
    33601 attgttgaat caacgatcga taataaggac gcttcaattt ttgtttgtct ggtcgccaag
    33661 ttaacgggta attgtcataa gaattaatag gcattttctc cactccttaa aattgtatac
    33721 catacaattt taccattgat tgtattgatt ttagaagtta atcttttgtg aggagggaat
    33781 tgtctatgaa aattattaat tttgaggaag tagtagcttc ttttagtttt gaagaagcga
    33841 ttcaagtaat gaaaaaatgt ttttttgatt atgaaagtgg taaaatcagc caaaatcctc
    33901 gattggtgga aattttacct gacggaaaag acaaaaatat gtttgcgatg atgcctgctt
    33961 atttggggga gaacagatat tttggaacaa aagtcattac cgcttttccg gataatcatc
    34021 agtatcattt accttctcat ttaggagaga ttttcttgtt tgatgctcaa aacggactac
    34081 ccaaagcatt gataaacgca aatgcagtca cctggattcg aacagctgct gtatctgcgc
    34141 tggcaacaga ttacttagca aatccgcatg cagaaacact tgctttaatt ggagctggtc
    34201 aacaagcatt gtcgcatttg actgcgattt ctaccattcg tcccatcact acagtgtttg
    34261 tttacgatat tttagaagaa agacgaaata cttttatcgc taaagctaaa aaacagtatc
    34321 ctaaaataac gtttataaat gcaatatcag tagaagatgc agtacgtcca gcggaaatca
    34381 tttgtacgtt gacctctagt aaagaggcat ttcttcaaaa agagtgggta agggaagacg
    34441 cacatatcaa tgctgtgggc acatttactc ctgatacaag agagataagt acatcgttga
    34501 tggaaacttc tcaaatctat gtagatgatt actcagctgc cttaacagaa agcggggacc
    34561 tgcttatagc catggcagaa ggagatttag aggaatcttg tattgttggt acattaggcg
    34621 aattagtttc tgagaaaaaa acattttata aaggagaatc gaggccgacg attttcgacg
    34681 cagttggtct agctattgaa gatctttgtt gtgcagaata tatttataac aaattagaga
    34741 aaggggcttt aaaatgaact tagattatta cgtagttgat gcatttgcag atgaggtgtt
    34801 caaaggaaat ccagcagcgg tttatgtgct agaagaatgg ctgccagaag gtacgatgca
    34861 aaaaattgcc attgaaaaca atttatctga aacagcattt acagtgaaga aaaaccaaga
    34921 atttgagctt agatggttta cgccagatcg agaaatcgat ctttgtggtc acgcgacatt
    34981 agcaacagca tttgttttat ttaactatta caaaatacct gatgaaacga ttaaattttc
    35041 tactcaaagc ggtaatctat ttgtgacaag aattaaagat tattattaca tggattttcc
    35101 tagtattatg ccgaaaaaag tgccgatatt gactgaatat gaagaagcaa ttggggctaa
    35161 gattaaagaa gcctacttag cacgtgattt atttttcgta ttagaagatg aaaaaacggt
    35221 ggctaaattg cagccagatt ttacagctat caaaaatttt gaattaggaa tagagtcatc
    35281 gtgacagcag aaagtgtgca aaaagacttt gtttctagaa ccttctttcc aaaattaaca
    35341 atcaatgaag atccagtatg tggatcagca cattctaatc ttattcctta ttgggcagaa
    35401 agaatgaata aaacaaaatt gtcagcttat caaatgtcat caaggggcgg ggatctagaa
    35461 tgtgaattaa aagaagatcg tgtgataata ggaggaaaag cagttttgtt ttctaaaggt
    35521 acctcgttta tttgatttct ttcaaatgaa ttaaaaataa attggtggag agtggcagcc
    35581 ttatagctac aatggttgtt aaaaaaagac gcaaactttt tcaatttaat gaaaagtttg
    35641 cgtctttttt taattattgg tgtttgtttt ttattcaatc aagagtaaaa tgccccatac
    35701 taactatcct cggatgactt cgattttata accatcaggg tcaatgacaa agtagtaaga
    35761 aggcgtagtg ccaggtaatc cttttaagtc agtaatctca agacctgcag ctttatgttg
    35821 ctcgtgtaat ttttctaaat catcagctgc aatagcgata tgaccatagc cgtctcctag
    35881 atcatacgca ccatgatcat agttgtaagt caactctaat tcatagtcat ctccaggaag
    35941 tgtcaaataa acaagtgtaa atttgttttc tggaaaatca cggcggcggc tttcttcaaa
    36001 accaaatgcc ttttgataaa attcgattga tgcttcaaga tctttcaccc gaacacatgt
    36061 gtgagccatt ttcataaatt catctctcct tttcctttta ctcaatcata acaaaaagaa
    36121 gtaagaaaat agttgatttg tgcttgttca tgagaaattt ctcatgtaaa atggatagaa
    36181 aataatactg ttaaggtgga aacaattcat ggataaacca atttttggtg aaaaaaagca
    36241 atctgctaat tatcaaaccc gttatgcagc atatattgtc atagaaagag acaagcggat
    36301 tgcggtgatc gaggctccaa atggtgcttt tttccttcct ggtggggaaa tcgaaggaga
    36361 agagacgaaa gaagaagcga ttgtccgtga gctgatagaa gaaatgggaa ttgtggcaga
    36421 aatttcttct tatctgggag aagctgatga gtatttttac tcgaattatc gtgcaactta
    36481 ttattataat ccaggatatt tctttgttgc tgattcttgg aagcgtatag gagaaccaac
    36541 tgaaaagacc aataaaattt ggtgggtgag ccctcaagaa gcgcttgtga aattgaaacg
    36601 tggtagccac cgatgggcag tcgagagatg gatcgaaaaa aataaaaact gaaagaaagc
    36661 gagtagatca gctttctctc agttttttta tttattacag tacatatttt ttgattgctt
    36721 cagctacacc gtgctcgtcg tttgatgaag tgatgacatt tgctgcttct ttgacaagag
    36781 aaacggcatt tcccattgct actcctagac cagcatattc aatcatggat aagtcgttct
    36841 cgttatctcc gatagccatg atttcatctt gatcaatacc aaggtgctgt gcgagattcg
    36901 caactgccgc acctttactt gcttctttat ttagtacttc gaagtaatag ggcgcacttt
    36961 tgaccgttgt gtatttatca cggaaagttt gcggtaaacg cgcaattgct gcatctaaaa
    37021 tttctggttc gtcgatcatc atcattttga cgatgttcat gtctggtgtc atttcttcag
    37081 gtgttcgata ttttagcggc atcttgacta aacttgcttc gtggatcgta taagcgctga
    37141 tatctcgatt aggcgtgtag atcgctttgt catcgatcga atggagatga ctgccgacac
    37201 ggcgtgccat cacttcgatc tctaggaaat cttcatgagt cagtccgtga cgggcgatga
    37261 ttttacctga tttcgtttgt tgtacgagtg ccccgttata agtaataacg taatcattat
    37321 cttgaaaaag gttcaactcg tttaactgtt cctggacacc tggtaaggga cggccagtgc
    37381 ataaaacgat cgaaacacct tttgcaacag cagcggcaat cgcttctttt acttcttttg
    37441 ttacttctct tttctcattt aataaagtac catcgatgtc gatagcgact agtttgatag
    37501 acataatttc ctccaatata ttttaattta tttcaatcaa tgcgccatta cggatatggc
    37561 tggcaaattc ttgataagtt tcgtcaaata aatcataatg atcacgcaag gagggatcaa
    37621 ccatttcttt tggaaagaaa aatcgctcat ctccttgttc ttgtcccgct aatgcagcaa
    37681 caagctgact aacctgtgat aattctatca aagttccgtc atttcgcaaa atctcgattt
    37741 gtgtgcgatg tctgccttgt tctgggcgat aaaaatcata aggcagatcg tagctagaat
    37801 tcacagcagt gtaataaaca gggttatagc caaccttttc tactaacaaa gtgagttctt
    37861 ggactaattt tgaatcccgg ttgccagaaa aagtagcaga tttcagtggt ttacgattca
    37921 aaaaacgttt agctaaatca tttaaaatag gatcagcaga ttcagaccat tgagtaaagt
    37981 aagtgcccaa gaccccatca tcaagtttga ggtattcttc taaagtaaag cttccgtcaa
    38041 gaaatggcag aagtaattga gaatggagtt caaaactgct ggcatcttct tgatacaact
    38101 cgtgtgcgcg atgaagcaga tgctccaaaa tcacttccat accacgggaa acaggatgga
    38161 agtacacttg cacatacatt tgatatcggc taacgatata atcttccact gcatgcatgc
    38221 cactcatgga aaaagcgatc ccgccttcat aaggacgaat cacacgtaat attcgggtaa
    38281 gatcaaatgt tccatattct gttccagtga aataagcatc ccgaagcaaa tagtccattc
    38341 gatctgcatc gatctgacta gaaatcattt ggacaacttg tgggttgggg taagtttttt
    38401 ggatcacact agctaccttt tcaggaaaac cttcttctac tcggttaaga atctgataca
    38461 cttctgtttc tggagaagtg atgatctcta cagtgatggc ttcatgattc gtatggaaga
    38521 tatgttcaaa tgtatgagag taaggaccat gaccgacatc atgcaacagt gccgcacata
    38581 aagtcaccag ccgttcctga tcatcccagc ctccgttgcc tattttttct tttgaaaaat
    38641 ttcgagaaaa gatatcgcag attcgtcttg aaatctcata aacgcctaat gaatgggtaa
    38701 aacggctatg ttctgctccg tgaaaagtga aagaagaagt gcctaattgt ttaatgcgtc
    38761 gtaaacgttg gacttctttc gaattgatca aatctaagat tactttatgc tggacatgga
    38821 tatagttatg gactggatca cgaaaaactt tttccatagg cagcatttga tatttataag
    38881 gggttgtcat aatgtagctc ctttatgtta ttacgttgtt ccattctctg gatttggttg
    38941 ttccattgct ccagctggat ttcttttttt agccagtcgg tagaatcctg taaatcactt
    39001 gcagaataca gcttttcaaa agcttttgca aatgcttctt tgacttcttt tacaaaaagg
    39061 ggttggtcaa gcagttcttc aagtgttgcc attgtagcag gatccactgc aggatagcca
    39121 tttgtaccaa agtcttcttt taaagcagat tgataaaatc gcttcatgac ttgcccgcgt
    39181 ttttcctgat taccgttgac acttaagtac atcataacag aaatcccatt tttgatccga
    39241 cgctgagcga taccggcaaa ttttttgcca tggatgctta aatcataagt tccaggacaa
    39301 taagaatggg tgatttcgaa tgcttgtatc ggtgcctttg gaaaagcgta tttagtcaat
    39361 aggagcattt gctcgtaagc gtcatctatg gttatttttt ttgtgtcact ttgagggaaa
    39421 atcaaagaaa tatttaaaat tccttcatct gatacgatcc ctaatccacc tgaatttctg
    39481 atcactggag cgtaacctgc atctttcagt gtttggatcc cgtcacttag aaaaggagtt
    39541 cgaacatcct tcatacctaa gatgactgtg cagtcatatt gccagaaatg taaaaagatt
    39601 tgctggtgtt ctttagaata ttccgttaat atatctgtta atgcaaaagg ggaaaagtcg
    39661 tttttttgat aaatgtgctg atctagtcga atcgcagggt tcattcaacc ggctcctttg
    39721 tataaattca tattttctac aatattatac tctaaaatca aagagttgtt ttggaaaaaa
    39781 ggttttctgt aaaaatggac aagttggttg acaaaacaaa agaaactagg aacaatgtag
    39841 ctatgagaag taaaggagaa tgaataatgg aattatcaca aggaacaccg atttcaatca
    39901 aattgcgtac aaaagtaaaa cagcaagggg aagtgcaaga tttttatttt gatttgaaag
    39961 ggcaaatggt gacaattggc gatacgctgt acatacgtta taaagagatt caggaggaga
    40021 cgggcgatga gattcctgta acgatcaaat tagttccaga tggtcatgta cagctgatcc
    40081 gtgcaggaga aatgcggatg cgtttgaaat ttggctataa agaacggtta gaaacatcct
    40141 atcgaacacc atacggtatg atccagattg ctacttttac gaaagaactg catgttagtt
    40201 tgaaagaccg tcccacagca gggaaggttc gaatcgatta tgatctgttc atgggaccgg
    40261 aaaaaatcgg cgaatattat ttgaccttgg attttacagc gtaaatataa aagaaaagtt
    40321 tgattttttg tgtctgattt tgtatgataa ggagtagact gtgaaaggac gtgtcctgat
    40381 tggaaattag tgtatttgaa ggtgcaaaca aaagcgaatt atcaatgatc gaagtagcac
    40441 acgcgatctt agaacaacgt ggcgatgtca tggatttttc tgatttagct aaccagatcc
    40501 aaaactatct tgagaaatca gacagtgaaa ttcgtgattc actcgcacaa ttttatactg
    40561 acttgaatat tgacggcagc tttatctcat taggggataa tcgttggggc ttgcgttcat
    40621 ggtatgctat cgattcgatc gatgaagaag taaaccatgg aatggacgaa gaggatgaag
    40681 atactccacg tcgccgtaaa cgcaagaaag tcaacgcctt tatcaatgat gatgaagacg
    40741 cgatcgatta caatgacgat gacccagaag atacagatct gacagaagaa gatgacgatg
    40801 atctgtttga tgacgatgat gatgaagatg aagaaatcgc tgcttataat tctgacttgc
    40861 aagaaatcgg agcagatgac ccgacagatg atgaagaaga cttgccagga aatatcgaag
    40921 aagatttaag tatcatagac gaagacgatg atgatgaaga ttatgaagag gaagaatttt
    40981 ctgactctga aaaagaataa acattatttt cttacgagag gttgtgacag agacgatcag
    41041 cctatcagaa taaggaggtg tgacacgatt tttgtcacac cttctttttt gtatataaaa
    41101 atcccaagta aatacataaa aaataaaaaa attgaaactt ttagcgcacc ttgtacgtca
    41161 tattaagtga ggcagaaagg agtggagaat gatttttact ggatataaga aaaaacggca
    41221 gatcgaaaaa taccgtcacc tgctgaatgg actcatcgaa actgattatc aaaaaatgtt
    41281 ccgtatcacg atgaattacg tacatgataa agaagaggcc ttagatgtga tgcaagatag
    41341 ttttcataaa gccttgaact attttgaaaa agaaaaagag atcgagcatt ttagtgcatg
    41401 gttttatcgg atattgatcc gcacggcatt agatagttgg cgcagacaaa aaaggacgcc
    41461 tgtggactta tttgaaattc aagatatccc ccaacagtta cctttagaaa cttccgttgc
    41521 agagctccat atgattttag ataaaataga cagtccggaa aaagagattc tgatcctcta
    41581 cttttttgaa ggatttcgtt tgaaagaaat tgcaactatc ttggatatga atgaaaacac
    41641 agttaaaacg aaaatgtacc gctcattgaa tgctttacgt caaatcctag aatgaaggag
    41701 agaagagtgc catgtattcc caaaaagaaa atttaaaaaa actaaagaaa acttataaag
    41761 aacaagcaat tcccaaaggg cttaaagagg agatccgcca gcgttttatt atcgaagagc
    41821 aatcatttat aaaagcaagg cggagaaaga gacgtctcca agggttcgga gtatctttgg
    41881 ctatcgtaat gattacaaca agtagccttc tttttaatag tcaagttcga agctttgcag
    41941 aagatttacc catcttagga tcagtcattg aattgatctt aggcgaacgc tttactgatc
    42001 gatctgaaaa aatcgatatt caggtaccga agatcaatac acaaaatgag aaagaaaata
    42061 aaacaattca tggattaaat caaaaatact ttcgcgaagg acaagcagat tttgaaaaag
    42121 ctgaaaaaga atatggaaat tttgaaacgg atcattacca agttttggga gattatcaga
    42181 aaatcgtaga cgataaccgg tttctcgtga ttgaaaggca gatcacccaa acagcagcag
    42241 atagccatgt tgaaaaaaga tacgacacaa tcgacaagaa aaacagtgtc cagctctcac
    42301 ttccactttt attcaaagat gacacttatc tatctgtttt gacaaaagaa gtcaaacggc
    42361 agatggccga acaagtcaag gaagatccat ctaagtacta ttggactgag caagatattc
    42421 aagaagggac gatagaaaaa ccaacacttg ttacgcctac acgaagtttt tatttgaaca
    42481 aagagcatca attagttttg actttttctc aatacgaaat tgctcctggt tatatgggta
    42541 caccagaatt tgtcattcct aagtccgtga caaaaacgat tttggcatcg gaagattatt
    42601 tggatcatta gacgagaagt agttgcgact agcagtttca attttcaagt aagtacaagt
    42661 aaataataag aagagaaaaa gagaaagaag agatatagtg aaaagaaatt atttagtcat
    42721 cagtattatt gctttatccg tgcttttgtt tttcgaaatt acttcggtgg cctccttgat
    42781 caccgaagta aaaggacaaa cacactcttc ggagcattcg tcacaatctt tcaaacaatc
    42841 agaacaatca accattaaaa gccaatcaac tgaaacagct aacgtcaaag aagccattca
    42901 agaatcagcg gaaaaggtac aaagtcaatc atcacaatca acacaagaca gtacagaagc
    42961 aatccaagac ccgactgtca aaagcgtcgc aatcagcttt gatgatggac caggagcgac
    43021 cacaacgccg cagcttctgc gaatcttaaa agaaaaaaac gtgcatgtca cttttttcgt
    43081 cttaggagaa aatacggcgc agcatcctga aatcgtgaag cagacagctg aagcagggca
    43141 cgagattggc aatcacacat acgatcatca gaatctggcc actctttctg cccagtcgat
    43201 gacggaggaa gtgacgaaag cagacactga gatcaaaaaa agtcactggc aaaacccccg
    43261 cttttgttcg tccgccctat ggttctgtca cgaatgtagg agcaacgatc atccagcgac
    43321 cgatcatcga atggtctgtt gattcagaag attggaagac aaggaatcct gatttgattt
    43381 tgcagaagat ccaagcaaca gtatacgatg ggtcaattat tttattccat gatatctatc
    43441 ctgaaacgat tcgtgccgtt cctcaagtga tcgattatct gaaagagcaa ggctatcgca
    43501 tcacgacagt tagcgattta ttagggcatc caacggctgt cgagaactat tatggcagaa
    43561 acgatcatcg gccagttcag taagtgagac aagtatcttt aataaataac acattttaat
    43621 aagtagttga acacataact accttacttg caaaggctta acaatatcta tacagataca
    43681 acaaaaaact gtccaccaat tctctttggc ggacagtttt cacttaaaaa taaagaagca
    43741 actattcgta aattatgcta aaatagcagt agaacgcgtc ctgagggaat cgaacccccg
    43801 tctcaagaac cggaatctta cgtgatatcc actacactaa ggacgcaagc actgggataa
    43861 ttgtaactaa acagataaaa aattacaagg ggattggaca aaaaaatgaa atttgagcaa
    43921 aatttttcac aaaaacagca gcagacacag aaactagcca tgacgcaaca gttgcaacag
    43981 tccatccaag ttttacaata taacagtgag gagctgttgg cattcgttga gaatcaagca
    44041 atggaaaatc cattggtgga agttgttgag ccggaatggc agccagatta cataaaagct
    44101 tcttcatctt cttatgaagg agaagagaca aattacctaa atcagattcc tgatacaaaa
    44161 gggtctttat ttgattcatt gatcgaacaa gtccatttga attaccgaga tacttttttg
    44221 aggaaaatcg ttctttatct tgtagaatac atcgatttga acggattttt gacgattagt
    44281 ttagaagaag ccggaaaaga gattggagct acgcctatcc aaatgctcga tgcgttgact
    44341 ctgattcagc aattagaacc agctggagta ggtgcacgta gtttgcaaga atgtctcatg
    44401 cttcaaacag aacgagatga ttatgcgccg gaattagctt atatcgtgtt ggaagaatgt
    44461 tttgaggaac tggtggagcg aaaatggaaa gaaatcgcac aacgtttttc tgttgatcta
    44521 catgctgttc agcagatatt cgactattta caaacgttga gtccaagccc tggccggatt
    44581 ttcgaccgta gcagcgaatt gtacattatt cctgatgtcc gggtattagt ggacgacgat
    44641 aaaaatgtac aagttatctc aaaccgaaaa aatcagccaa atatacgctt tcaagagagt
    44701 tacttcaaac aaatgtcaca acaagcagat aaagaaactg aaaattattt aaaagaacgg
    44761 aaacaggaat tcgaatggtt gaagaaaacg atcctacaac gtggggatac aattttgcgg
    44821 gttgctcaag tcattgtttc ccggcaaaaa gctttcttta tcgacaagga acgtccaatc
    44881 aagcctctta cgttaaagga agttgcaact gagatagatg tgcatgaatc cacggtcagt
    44941 cgtgcagtca acgggaaata tttggaaaca gacttcggtg tatttgaatt aaaaaaattt
    45001 ttcactacac gaattcctac gaatagtaca gaacagacag aagacctttc agcagataca
    45061 gcgaagaaaa agctgcagga attagtcgat caagaagaca aaaacaagcc gttgtctgac
    45121 cagaaattgg ttgaattgct gaaaaaagat gagatagcga tctcaagacg aacagtagca
    45181 aaatatcgtg atttattagg aatcccgagt tcatcaaaaa gaaaacgtta tgataactaa
    45241 tcagtcaaaa gactagaaaa agtatttcac tttttctagt ctttttagtt gaaaaacgag
    45301 agcaaaactg ttagacttac agtcgtgagg ttgagatttc cctttattga tgtgaaattc
    45361 gaatagttaa tttctttttt tatcgtatat gggtcgtttt aagtctacat tggacgtaaa
    45421 gtgtccaact aaggagatcg ctatgctgga tgaaataaaa atgattgaat ctgttgcacc
    45481 agatattatc gaagtgttgc aagaacgcta taaaatttta cgaaatatct attggatgca
    45541 gccgattggg cgtcgaagtt tatcggaaag tatggggatc acagaacgag tcttacgaac
    45601 agaaacagac cttttgaaaa atctgaattt gatcgacacc tcaaaaagcg gtatgacgct
    45661 gacaactaag ggcgaagaag tttatcaaag ccttgaaaac ttcatggatc agcttttagg
    45721 tacgcatcaa accgaacaac agttggcaga atattttggt aaccaacgct gtatcgttgt
    45781 ttcaggaaac agcgaagagc agaccaaagt ggctgatgca ttcggcgaag cgctgagcga
    45841 agccttagac cgactacttc cagaaggcga gaatatcatc gctgtgatgg gaggaactac
    45901 tatggctgtg gtagccgaac aattgtctaa tctggaaaat aagaaacggc ataacctgtt
    45961 tgtccctgca agaggcggga ttggtgaagc gataactgta caggcaaatt ctgtcagtgc
    46021 aagaatggct gctaaagcaa acggtaacca ccgcgcactt tatgttccgg aacaattaag
    46081 tctggcaact tacaattctt tactcaatga gccatctatc caagaagtct taaacttgat
    46141 tagtgaagcg aattgtgtta ttcatagtat tgggcgtgca ttacacatgg cagcacgtcg
    46201 taagatgact gaaaaagaat tagtcatgct gaaacaagca aatgctgttg cggaatcttt
    46261 tggctacttt ttcaatgaaa aaggtgaagt cgtttataag gtccctagaa tcggcataga
    46321 attgcaagat ttggaaaaag tcccgatcat catggcaatc gcgggcggaa aatcaaaagc
    46381 taaagcaatt cgagcttata tgaaaaatgc accaaaacaa acgtggctca tcactgatga
    46441 agctgctgca aatgagattt taaaaggggt aaccctttaa aataaatatt tttttgattt
    46501 tcataaggag gaaatcttaa atgacagtta aagtaggtat taatggtttt ggacgtattg
    46561 gacgtctagc attccgtcgt atccaagatg tagatggaat cgaagtagta gcaatcaacg
    46621 acttgacaga tgctaaaatg ttggcacact tgttaaaata cgacacaact caaggacgtt
    46681 tcaacggaac agttgaagtt catgaaggtt cattcaacgt aaacggaaaa gaagttaaag
    46741 tattagctaa ccgcaaccca gaagaattac catggggcga actaggcgta gatatcgttc
    46801 tagaatgtac tggtttcttc acttctaaat cagcagctga aaaacattta acagctggtg
    46861 ctaaacgcgt tgttatctct gctcctggcg gaaacgatgt tccaacaatc gtttataaca
    46921 caaaccacga aacattaact ggtaaagaaa cagttatctc aggtgcttca tgtactacta
    46981 actgtttagc tcctatggct aaaacattga acgacaaatt tggtgttgtt gaaggattaa
    47041 tgacaactat ccacgcttac acaggtgacc aaatgactct agacggacct catcctaaag
    47101 gtgacttccg ccgtgcacgc gctgctgctg caaacatcgt tcctaactca acaggtgctg
    47161 ctaaagctat cggtttagta attcccgaat tgaacggtaa attagacgga gctgctcaac
    47221 gtgttcctgt accaacaggt tcattaacag aattagtaac agttcttgaa aaagaagtaa
    47281 ctgttgacga aatcaatgca gcaatgaaag aagcttcaaa cgaatcttac ggatacaaca
    47341 cagacgaaat cgtttcttca gatatcgttg gtatgactta cggttcatta tttgatgcta
    47401 cacaaactaa agtaatgaca gttggcgaca aacaattagt taaaactgtt gcttggtacg
    47461 acaacgaaat gtcatacact gcacaattag tacgtacttt agaatacttc gctaacttat
    47521 aagatagaca aacgtacaag tgtaaattat agacatgtac atttaaaagc ggggaagcaa
    47581 tcgcgcttct tccgcttttt ttgataataa gtttattcag gaggaaataa aatggctaag
    47641 aaaacagtga aagatatcga tttaaaagac aaaaaagttc ttgtccgtgt tgacttcaac
    47701 gttcctttga aagacggcgt gatcactgac gacactcgta tcaaagcagc attgccaaca
    47761 atcaactacg ttctagaaca aggcggaaaa gcaatccttt tctctcacct tggacgtgta
    47821 aaaacagaag aagataaaga aggaaaatct ttagctccag ttgcaaaacg tctaggcgaa
    47881 ttattaggta aagaagtaac attcgtacct gaaactcgcg gagaacaatt agaagaagca
    47941 atccgcaaca tgaatgacgg cgacgttgtc gtattcgaaa atacacgatt tgaagatatt
    48001 gacggtaaaa aagaaagcaa aaatgataca gaactaggta aatactgggc ttcattaggc
    48061 gatgtatttg ttaacgatgc tttcggtaca gctcaccgtg cacatgcttc taacgtaggt
    48121 atcgcttcaa ctggtatccc aacagttgct ggattcttga tggaaaaaga aatcaagttc
    48181 atcggtgaag cagtagaaga accaaaacga ccaatgattg caatccttgg tggcgcaaaa
    48241 gtttctgata aaatcggcgt aatcgaaaac ttgattccta aagcagataa aatcttgatc
    48301 ggtggcggaa tgacttacac attctacgaa gcaaaaggaa tcaagatcgg taactctcta
    48361 gtagaagctg ataaagtgga actagcaaaa gaattaatcg aaaaagcagg cgacaaactt
    48421 gtcttgccaa tcgacaatgt ctgtgcacca gaattttcaa atgatgttga aacacaagta
    48481 atcgaaggag acattcctga tggtttgatg gctttagaca tcggcccagc atcagtaaaa
    48541 ttatttgctg atacattaca aggtgcaaaa acagttgttt ggaacggacc tatgggtgta
    48601 tttgaaatga gtaactttgc taaaggtaca atcggtgttt gtgaagcaat cgctaactta
    48661 gaaggcgcaa caacaatcat cggtggcgga gactcagccg cagcagcaga acaattagga
    48721 tttgctgaca aattcacaca catctcaaca ggtggcggcg caagcttgga attgcttgaa
    48781 ggtaaagaat taccaggact agcagcaatc aacgataaat aaacgaccaa gtttgctcaa
    48841 ttctgacgag taatcgaaca aaaggtgaag ggagttttca tgactcccta gccatttttc
    48901 aataaattaa ggagtgtgtt cctcaatgcg taaacctatt atcgcaggta actggaaaat
    48961 gaacaaaact gcatcagaag caaaagaatt tgctgaagca gtaaaaaaca aaatcccttc
    49021 aaatgacaaa gttgattcag tcatcggatc tcctgcatta ttcttacaag aattaatgac
    49081 atcagctgaa ggtacagaac taaaaatctc agcacaaaac tgctactggg aaaactcagg
    49141 tgcgttcact ggtgaaactt caccagcagc tcttgctgat ctaggtgttc attatgtgat
    49201 catcggacat tcagaacgtc gtgaatattt ccatgaaaca gacgaagaca tcaataaaaa
    49261 agcgaaagct atctttgcaa atggtatgac accaatccta tgctgcggcg aatctttaga
    49321 aacctatgaa gcaggcaaaa ctgctgaatg gatcgaagga caaattacag ctggtttagc
    49381 tgatctttca gctgaacagg tgtcaaacat ggttattgct tatgaaccaa tctgggcaat
    49441 cggtactggt aaatcagctg acgcacaaat cgctgacgaa atttgtggag ttgtacgtca
    49501 aacagttgaa aaactttatg gaaaagaagt atcagaagca gttcgtatcc aatacggcgg
    49561 ttctgtaaaa ccagaaaata ttgctgaata catggcaaaa gaaaatgttg acggtgcttt
    49621 agtcggtggc gcaagcttgc aagcagattc attcttgtca ttgttagacg ctgtaaaata
    49681 attgttgaaa atttgcgaaa aatgcaagaa atgtttgcac taatgagcaa aattaactaa
    49741 aatcgtatat gagggaaatc ccttaggaaa aaacaaactc aaaggagaga caaaacatgt
    49801 caattattac tgatgtttac gctcgcgaga tcttagactc acgtggtaac ccaacaatcg
    49861 aagtagaagt atacacagaa agcggagctt ttggccgcgg aatggttcct tcaggtgctt
    49921 caactggtga atacgaagca gttgaattac gtgacggaga caaagctcgt tatggcggta
    49981 aaggtgtaac taaagctgtc gacaacgtaa acaacatcat tgctgaagca atcattggct
    50041 acgatgttcg tgaccaaatg gctatcgaca aagctatgat cgctttagac ggaactccta
    50101 acaaaggtaa attaggtgcg aacgctattt taggtgtttc tatcgctgtt gcacgtgcag
    50161 ctgctgacta cctagaagta cctttatacc actacctagg cggattcaac acaaaagtat
    50221 tgccaacacc aatgatgaac atcatcaacg gcggatcaca tgctgataac tcaatcgact
    50281 tccaagaatt catgatcatg cctgttggcg ctccaacatt caaagaagct ctacgtatgg
    50341 gtgctgaagt attccacgca ttagcttcaa tcttgaaagc tcgcggatta gcaacttctg
    50401 ttggtgacga aggtggattt gctccaaacc ttggttcaaa cgaagaaggt tttgaagtaa
    50461 tcatcgaagc aatcgaaaaa gctggctatg tacctggtaa agacgttgtt cttgctatgg
    50521 atgctgcttc ttcagaattc tacgacaaag aaaaaggtgt ttacgtacta gctgactcag
    50581 gcgaaggcga aaaaacaact gacgaaatga tcaaattcta cgaagaatta gtttctaaat
    50641 atccaatcat ctcaatcgaa gatggattag acgaaaacga ctgggacgga ttcaagaaat
    50701 taactgacgt attaggcgac aaagttcaat tagttggtga cgacttgttc gtaacaaaca
    50761 ctcaaaaatt atctgaaggt atcgaaaaag gaattgctaa ctcaatcctt atcaaagtga
    50821 accaaatcgg tacattaaca gaaactttcg aagctatcga aatggctaaa gaagctggct
    50881 acacagcagt tgtatctcac cgttctggtg aaacagaaga ttcaacaatc tctgatatcg
    50941 ctgttgcaac aaacgctggc caaatcaaaa ctggttctct atcacgtact gaccgtattg
    51001 ctaaatacaa ccaattacta cgtatcgaag accaacttgg tgaagttgca gaatacaaag
    51061 gtttgaaatc tttctacaac ttaaaaaaca aataattctt ttctaatgaa gatacatgat
    51121 cgactattga aagatagtcg agtatgatca cttagttaag taatcgaact ctctacttgc
    51181 tgaaatatca gcaggtagag agtttttttg caactagctt ctgtatatga tgtttacaaa
    51241 gaatggtaca agaaaagatc atccttgaaa aaggaaagct aacaataact agcatcatat
    51301 aagagctttt aaggatagaa cagtagaata ggaatctatg ggcaagtcct ctcgtataaa
    51361 ta
//
LOCUS       DACGMI010000016        49639 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.016, whole genome shotgun sequence.
ACCESSION   DACGMI010000016 DACGMI010000000
VERSION     DACGMI010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.016"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            169..1227
                     /locus_tag="IXT46_001040"
     CDS             169..1227
                     /locus_tag="IXT46_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAQ4946967.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1246..2265
                     /locus_tag="IXT46_001041"
     CDS             1246..2265
                     /locus_tag="IXT46_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAQ4946968.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(2367..3083)
                     /locus_tag="IXT46_001042"
     CDS             complement(2367..3083)
                     /locus_tag="IXT46_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAQ4946969.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3052..3837)
                     /locus_tag="IXT46_001043"
     CDS             complement(3052..3837)
                     /locus_tag="IXT46_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4946970.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3828..4577)
                     /locus_tag="IXT46_001044"
     CDS             complement(3828..4577)
                     /locus_tag="IXT46_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAQ4946971.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4875..5399
                     /locus_tag="IXT46_001045"
     CDS             4875..5399
                     /locus_tag="IXT46_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946972.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTDERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5415..6914
                     /locus_tag="IXT46_001046"
     CDS             5415..6914
                     /locus_tag="IXT46_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAQ4946973.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(7002..7604)
                     /locus_tag="IXT46_001047"
     CDS             complement(7002..7604)
                     /locus_tag="IXT46_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4946974.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7708..8664
                     /locus_tag="IXT46_001048"
     CDS             7708..8664
                     /locus_tag="IXT46_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAQ4946975.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8969..9925)
                     /locus_tag="IXT46_001049"
     CDS             complement(8969..9925)
                     /locus_tag="IXT46_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4946976.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10099..10659
                     /locus_tag="IXT46_001050"
     CDS             10099..10659
                     /locus_tag="IXT46_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946977.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10652..11476
                     /locus_tag="IXT46_001051"
     CDS             10652..11476
                     /locus_tag="IXT46_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAQ4946978.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11486..12103
                     /locus_tag="IXT46_001052"
     CDS             11486..12103
                     /locus_tag="IXT46_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAQ4946979.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12121..12804
                     /locus_tag="IXT46_001053"
     CDS             12121..12804
                     /locus_tag="IXT46_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAQ4946980.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13487..14770
                     /locus_tag="IXT46_001054"
     CDS             13487..14770
                     /locus_tag="IXT46_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4946981.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14786..15673
                     /locus_tag="IXT46_001055"
     CDS             14786..15673
                     /locus_tag="IXT46_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4946982.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15690..16526
                     /locus_tag="IXT46_001056"
     CDS             15690..16526
                     /locus_tag="IXT46_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4946983.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16529..17152
                     /locus_tag="IXT46_001057"
     CDS             16529..17152
                     /locus_tag="IXT46_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946984.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17149..18441
                     /locus_tag="IXT46_001058"
     CDS             17149..18441
                     /locus_tag="IXT46_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4946985.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18800..18897
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            19013..19594
                     /locus_tag="IXT46_001059"
     CDS             19013..19594
                     /locus_tag="IXT46_001059"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAQ4946986.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19597..20904
                     /locus_tag="IXT46_001060"
     CDS             19597..20904
                     /locus_tag="IXT46_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAQ4946987.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21320..21808
                     /gene="purE"
                     /locus_tag="IXT46_001061"
     CDS             21320..21808
                     /gene="purE"
                     /locus_tag="IXT46_001061"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAQ4946988.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21792..22925
                     /gene="purK"
                     /locus_tag="IXT46_001062"
     CDS             21792..22925
                     /gene="purK"
                     /locus_tag="IXT46_001062"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAQ4946989.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22938..24233
                     /gene="purB"
                     /locus_tag="IXT46_001063"
     CDS             22938..24233
                     /gene="purB"
                     /locus_tag="IXT46_001063"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAQ4946990.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24413..24790)
                     /locus_tag="IXT46_001064"
     CDS             complement(24413..24790)
                     /locus_tag="IXT46_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4946991.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            25046..25774
                     /locus_tag="IXT46_001065"
     CDS             25046..25774
                     /locus_tag="IXT46_001065"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAQ4946992.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            25774..26028
                     /gene="purS"
                     /locus_tag="IXT46_001066"
     CDS             25774..26028
                     /gene="purS"
                     /locus_tag="IXT46_001066"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAQ4946993.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            26030..26701
                     /gene="purQ"
                     /locus_tag="IXT46_001067"
     CDS             26030..26701
                     /gene="purQ"
                     /locus_tag="IXT46_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAQ4946994.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            26702..28924
                     /gene="purL"
                     /locus_tag="IXT46_001068"
     CDS             26702..28924
                     /gene="purL"
                     /locus_tag="IXT46_001068"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAQ4946995.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            28909..30348
                     /locus_tag="IXT46_001069"
     CDS             28909..30348
                     /locus_tag="IXT46_001069"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAQ4946996.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            30380..31423
                     /locus_tag="IXT46_001070"
     CDS             30380..31423
                     /locus_tag="IXT46_001070"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAQ4946997.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            31420..31998
                     /gene="purN"
                     /locus_tag="IXT46_001071"
     CDS             31420..31998
                     /gene="purN"
                     /locus_tag="IXT46_001071"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAQ4946998.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            31995..33530
                     /gene="purH"
                     /locus_tag="IXT46_001072"
     CDS             31995..33530
                     /gene="purH"
                     /locus_tag="IXT46_001072"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAQ4946999.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            33546..34820
                     /gene="purD"
                     /locus_tag="IXT46_001073"
     CDS             33546..34820
                     /gene="purD"
                     /locus_tag="IXT46_001073"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAQ4947000.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            34942..35856
                     /locus_tag="IXT46_001074"
     CDS             34942..35856
                     /locus_tag="IXT46_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAQ4947001.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(35989..37554)
                     /locus_tag="IXT46_001075"
     CDS             complement(35989..37554)
                     /locus_tag="IXT46_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAQ4947002.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(37547..38998)
                     /locus_tag="IXT46_001076"
     CDS             complement(37547..38998)
                     /locus_tag="IXT46_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4947003.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIRESKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(39012..40028)
                     /locus_tag="IXT46_001077"
     CDS             complement(39012..40028)
                     /locus_tag="IXT46_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4947004.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSLQNIANIP
                     TRNY"
     gene            40248..41336
                     /locus_tag="IXT46_001078"
     CDS             40248..41336
                     /locus_tag="IXT46_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAQ4947005.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            41390..42916
                     /locus_tag="IXT46_001079"
     CDS             41390..42916
                     /locus_tag="IXT46_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947006.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            42918..44123
                     /locus_tag="IXT46_001080"
     CDS             42918..44123
                     /locus_tag="IXT46_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4947007.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            44380..45357
                     /gene="guaC"
                     /locus_tag="IXT46_001081"
     CDS             44380..45357
                     /gene="guaC"
                     /locus_tag="IXT46_001081"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAQ4947008.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            45621..47045
                     /locus_tag="IXT46_001082"
     CDS             45621..47045
                     /locus_tag="IXT46_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAQ4947009.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            47506..48615
                     /gene="pdhA"
                     /locus_tag="IXT46_001083"
     CDS             47506..48615
                     /gene="pdhA"
                     /locus_tag="IXT46_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAQ4947010.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            48618..49595
                     /locus_tag="IXT46_001084"
     CDS             48618..49595
                     /locus_tag="IXT46_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAQ4947011.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT        15833 a         8540 c        10921 g        14345 t
ORIGIN      
        1 ttttttgtgt tctagtaaaa atcactttac ataagtttca aaagtttctt taatttccta
       61 ttgttcaata agtaacaatg taaagataaa attaaaaatg ttaatacgta ttagcaaaat
      121 aaaagctttt tttattgtga ataaatgaac ataattagga ggagaaagat gaacttattt
      181 gacatttttc gatcgacttt gacagatatg tcgattgtca gtgcaatcac ttcaacagtt
      241 tttattatat tattagggtt tgtttgtaga aaaaagggga ttttttctga atctgttgga
      301 aaaattctat cgaaagtcgt cttaacagtg gctttgccag cactggcatt tcgagctttc
      361 atgcaagata tcaatacaga attactgatg caaggaatca atgtcttgat ttggggatta
      421 gttatttata ttattcttat tctagtttca aaaccttttt tcttaagcta taaaggggat
      481 aagcaaacaa cgttgcgtgt cctgacgatc tttggttcta cgaccttttt cggaacgcct
      541 atcgtcagtg cgatttatgg tcctgtcggc gtgatgtatt cctcaatttt caatattggc
      601 taccgaatct ttttgtattc ttatggatac ataaaaatga gtggcttgaa gatggaagct
      661 aaaaatatca aagcgatgtt cgtcaatcca atcattatcg ctacttttgc cggccttttc
      721 atttggctgt tccaagggta tctgccacaa gtgtcagtta caggtgcaga aggagagata
      781 agccaagtag cgtttttgcg aattgaccag actgcaccgt ggctatttca gccgatggat
      841 tatttagctg gtttaagttc accattggcg tggctagcaa tcggcgcaac attaggtgaa
      901 gtaagcttca aaaaagctgc atctgaaaaa acttcatggt attacagtct agtcaaagtg
      961 gtatttgtac ctgcattgaa tatcgtgatt ctagcagttt tgacggcaac gaatattcta
     1021 ccagtcaatt ttgaagcact ggcaacaatc gttatcatga tggctacacc agctgcaaca
     1081 gtggcagcag cctatgctat cagttttgat agggaggcac ttttagcctc caatgcatcc
     1141 ttactgtcaa ctatttttgc tgtggtactg acacctgtat ggatcgttgt attacaaatg
     1201 attcatggca taggtttatt ttcataagaa atggaggaag aaagtatgag aatcgcatgt
     1261 tacggtgttc gtccgaacga gatagatttt tttgaaaaat tgaatattta ccattatgat
     1321 ctcagtcttt atgaagaact gttgacacat gacaatatcg tgtcagcaaa ggaccatgat
     1381 gctgtattgt tgaggggaaa ttgtatagca gatgagacca atcttgcaaa aatgcaggaa
     1441 tatgggattc gttatgtttt tacacggact gtgggagtca atcatatcga tctacaagcg
     1501 gcagctgatt ttggtatgac agtagcccgt gtaccatcgt attcgccaaa tgcgatagca
     1561 gagttatctt tgacttttgc catgatgctt ttgagaaata ctgcgtatac gacgatccga
     1621 acatctttca aagattttcg agtggatgag caaatgttta gtcgtgaaat cagaaattgc
     1681 acagtaggga tcataggaac aggcaggata gggttgacgg aagctgtttt gtttaaggga
     1741 ctaggagcca aagtgatcgg ctacgatatt catcagacag aagctgctaa aaaagtattg
     1801 acgttccact cgcttgaaga gttattagcc aaaagcgata ttgtcagtat tcatgtacct
     1861 catatcccag gtgaaaacga tcaaatgatc aatgaaggat ttttagctca aatgaaaaaa
     1921 ggtagcatct tgattaatac agcccgtgga gagcttcaag ataatgaagc tattttaaga
     1981 gctttgaaaa gcaatcattt agctggtttt gcaaccgatg tttttgcaaa tgaaacagag
     2041 gtttttttcc gatccttcaa gccatgggag acgattccag accctgctat ccagcaatta
     2101 gtagaaatgt accctagagt tcttgtaacc ccgcatgtag gttcaaatac agatgaggca
     2161 ttatcaaata tgatttcgac aagtttcgag aactttcgtg aaataataga aactggaaaa
     2221 acgaaaaatg aggtatctct tcctaaagcc cgtcaattaa gataagaaaa catggatatt
     2281 cgtcaataaa atgtttaaaa atagtccaag taaacagttg ttacttctgt atacttggac
     2341 tattttgtat gggataattc gatgactcaa cagtaatctg tgagcttttt ccgcccattc
     2401 tttgtcaatt cataacaggt tagcggccgg ccgatttcca aatatttgat tctttcgttc
     2461 aatatatctt gttctactaa aaaattcaaa tatttcttga cggatatacg tgacagtgag
     2521 cttttttgag ccagttcttt tgttgaaaaa atagtatctt cttttagaat aaatgcactt
     2581 atttttttta aagtcagttt tgacagacct ttaggcaaat cgatgaatga tggtatttcg
     2641 tgaatgggag tggtgtggtt gaatacttga tcgatcaatt tctgatcggc tttttcagtc
     2701 gtttggattg tctgagagaa agcaagatac ttttcgatcg ccagctgaaa acgttgcaaa
     2761 gtgaacggtt tgatcaaata atctaaggca ccgtagcgga tcacattctt tatggtttcg
     2821 atatcatctg cagcagtgat caaaatcact gggatatcat ttccttgctg tctaagccaa
     2881 gataaaaaat ggataccact ttcgccaggc atgtatacat caagcagcag cagatctgcg
     2941 tttttttgtc tgaaatattt ttttccttct tctacatttc tgaaactttc gattacgttc
     3001 atattaggga tgctttccac aaaagtacga ttcaattctg caaccattgg atcatcttcg
     3061 attatcagga catttgtcat cattttgatc ttcctttttt ggtaattcta gatagacgat
     3121 tgtaccgcca tttgtttgtt tggaaaattc taaaaatcca ccgtggcgtt tgacgattga
     3181 atggatgaga ttcaatccaa acccacgatt gattcccttc gtcgaaaaac ctagcgtaaa
     3241 tattttttct gagatttctt ctgatatccc gacaccgtca tcgcagacgg tcacgatgaa
     3301 tacttcagct tctgtgtcat agtttaaatg aatccggacc tgtccgtttc tttcatgttt
     3361 ttgtagcacg gcttcttttg cattatcaag taagttccct aacacttgca aaagtgaatg
     3421 gatggagtca tccatctcca ttttagggat aaaagaatcg ctttctaaca gcatttcaac
     3481 agattgttct ttggcttcgt ttattttgcc taataaaaaa ccggcaattg caggtacttt
     3541 gatcagactt gagacttggc caatctcttt tttataattt tgatttagct gctggataaa
     3601 atgggtgact tcttcatact tcttcaaatc aatcaaacca gaaatgacat gaagtttatt
     3661 catgaattca tgggtttgag ctctcatgga gtttatatat tgtttcgtcc ccccaagctc
     3721 ctccattaat ttcattactt ctgatcgatt tcgtaaagtt gcgactgctc ctaaaaaacg
     3781 gtcattgcta aaaagaggtg taacgctaga aatagtttct atcccattta aatacatgga
     3841 ttgagtccga acggtcgttt gatgctcaat cgtctcttta aacaaaacgt catatagatt
     3901 atcactgatt tttttcctac ttcgaaatcc aatagctgct ctgtttggta gaaaatgttt
     3961 tttgcaggtg tattgatcaa gaggatagtt ttatcagaag agatggctaa gattccttca
     4021 tctacttcat tttcgataat cgttttttca cttaactgtt ctgctatttc ttgtggttca
     4081 agtccaagca gtactttttt cattttttgg gcaagaaaaa cggcgcctat gatgcctacg
     4141 ctaagtccaa taatcaatga aaaaacaatc attttttgtc catctttgac ttgattgtca
     4201 atcgtgttgt ttgttaagcc aacacaaact gcaccaataa tctcttgatc ataataaata
     4261 gggacgaaat agcggaagcc gaaccctaac attccttctt tttcagagaa aaattcttgt
     4321 cctccaatca cttttttcac atcttcatga cttgagaaag gaagaccgat gtaacttggg
     4381 tctgcgtgag aatatcgaat gccttcaggg tccatgacaa cgataaaatc taaattcgat
     4441 gcaatcatga tttcatttgt tattccttga atcgcatgtg tcgggtcacc agtctgcagc
     4501 tttttttgga tgagtttatc attggcaacg attttagcaa tgctagagat tttatctgac
     4561 acactagatc ggttcatcga aagaataaaa ttcctgatca atatggcaga aacaatcaaa
     4621 gaaacgaatg tggagaaaca aacgacaagg atgatcgtgt tctggagctt taatggtttt
     4681 ttcttaaaaa aaggaaacat aggctacctc gaaagaattt attgtgaaaa ttttaacatg
     4741 aaaacaaaaa tttaacaaat tgtcaacgat aaacacaacc ttcctataaa aaacaccact
     4801 gagtcggtaa aagaagctat acagaatttt caaacattgg tatgatagac gtagaaatgg
     4861 aaggaggcgt gtatatgata gggggaatcg cacttgagac gatttattgg tatacattgc
     4921 tgatttgtgc aggattggca gtcctattga ttatttttgg agatgtattc gattttgatg
     4981 gcccgcttga tccgatgctt attatccctt ggttaacttt cacaagctta tttggttttc
     5041 taggtgagcg tttaacagat caatcatctt tatttttatt tattgctagt ggaggcatat
     5101 cgatagtgtt ggtatttttg cttaatttct atatattgat gccgatgaaa catgccgaat
     5161 caacgatgtc gtcttctgaa aaaactctgg aaggacaagt agctgttgtg atcacaccga
     5221 tccctgtacg aggtatggga gaaattcagt tgaaaagtgt taccggttcc attagtcgtc
     5281 cagcttgttt ttacagcccc caagaacaga cagatgagcg gggaacgaaa gtattgatca
     5341 ttgagatcaa ggaaagaatc tgttatgtca tgccttatga aagcatgata aaagcttaaa
     5401 ggagcgtgtg ttaaatggaa ataccagttg tttttatcgc gatcgcaatc gcagctttga
     5461 ttttactgat gttgctgatc gtctttgtag cgaagtacca gacagcaaaa ccggatgaag
     5521 cgttgatcat cagtggaagt tatttaggaa gcaaaaatgt gcacattgat gaaagcaata
     5581 acaaaatcaa aattgtgcgt ggaggtggcg cattcgtctt gccagttttt caacgttcga
     5641 atcggatcag tctattatcg agtaaattgg acgtctccac ccctgaagtg tatacggaac
     5701 aaggcgtacc ggtgatgtgt gatggtactt cgatcatcaa aatcggttca tctgtagaag
     5761 agattgctac agcagcagaa cagtttttag gcaagacaag agaagaactg gaaaatgaag
     5821 caagagaagt attagaagga cacttgcgct cgattcttgg ttctatgact gtagaagaaa
     5881 tctatcaaaa tcgcgataag ttcagtcaaa gcgtacaaga agtcgcttct gtagaccttg
     5941 caaaaatggg gttgatcatc gtttctttca ctatcaaaga ggtcagagac aaaaacggtt
     6001 atcttgactc tttagggaaa ccaagaatcg cccaagtcaa aagagatgca gatatagcag
     6061 aagcggaagc tctaaaagaa acgcgtatca aaaaagctca agcagaaaaa gaatcacaag
     6121 cagctgaatt acagcgacaa acagagatcg cagaatcatt aaaagaaaaa gaactgaaat
     6181 tagcaaccta caaacaagaa caagatgttg ctaaagcaaa agcagaccaa gcctacaatt
     6241 tagaaagtgc ccgagcacaa caacaagtaa tcgaacagga aatgcagatt aaaatcgtag
     6301 aacgtcaaaa acaaatcgaa ctggaagaaa aagaaatcac acgtcgtgaa aagcaatatg
     6361 attcggaagt gaagaaaaaa gcagatgccg atcggtacgc taaagaacaa gaagcacaag
     6421 ctcaaaaagt caaagaagtg actgaagccg aagcagaacg attccgtgtg gaagcactgg
     6481 cagaagcgga agccaataag acacgtttag ctggacaagc agaagccgaa gcagcactag
     6541 caaaaggaaa agcagaagcc gaagcaaaac aaaagatcgc caatgccttc aaggaatatg
     6601 gcgaagcagc tgtcttgagt atggttatcg atatgctacc gcaattgatg cgcgaagcag
     6661 cacagccgct aggaaatatc gaaaaaatct ctgttgtcga tacaggaagc agttcaggag
     6721 aaaccagtgg agcgaaccga gtgacaaatt atgccacaaa tttgctttct tctactcaag
     6781 aaacactaaa agcgacaaca ggacttgact tgaaggaaat cgtagagaat ttgtcgacac
     6841 gtgggactac tagccaagta aatatgtatg aagcgccaaa agaggcagaa caaaactcga
     6901 tgaaggaaga ataaagtagt acacttcacc gttcaatcaa aaatggagga agacttttta
     6961 aagttcttct ctccattttt ttattttatt gcaaaagaaa attagtcctc gctatttttc
     7021 ttttgttttt ggatcttagc ttctatctct tgtaaatttg ttcttagcaa tcgttctttc
     7081 ttttggagtt cgaccaaatc ttctgatagt tcttccttct tttctgtttc aggaggacga
     7141 agaaagaaat tgataccgat tgcaatgaat gtccctataa aagtatctag tacacgttgg
     7201 atagcataca aagcggattc gccttgaggg atgctcaacg caatcagcaa caacgtagct
     7261 attgcggaaa tgataccgga attattgtta ataccatctg acacgacgat cacaataata
     7321 actagaatag gaagcaagat caattctacc aaaaaatcat tgtgaaaata gcttttgaca
     7381 aaaaaataaa tgatagctaa tgtaccacct aatgtattgc cgatgatcct agactttcca
     7441 aaagaaacgg ttgtagtcaa gtcctgacgc aaagaaaaaa cagcagataa tgcagcaatc
     7501 atcgggattc ctcgttgagt caaatgaaaa aacaagatac ataaaaaaac agctaaggca
     7561 cttttgatcg tacgcatacc tagtcgaaaa cggccaaatt gcatagagat tctccttttt
     7621 ggtcttttta ctatcatacc taaacttttg tctgatagct agtttttcat tattcaagta
     7681 taattaaaat aaaaaagggg gaagtaaatg cgtataggaa tgcgaacagt caaaacagtg
     7741 atcagtgtct tcttttcgat ggtcacagcg ggtagcttat cgctgttgta ttggccagct
     7801 gcagggatca ttgcattatt aagtgtagga aataccaagc gctctacatt gcgtacgggc
     7861 atgaatcgaa tcgcagcctt tatattagct acggcaacag cactgttcag tttttttgct
     7921 gttgggtata ctatttttgg cttcagtctt tttttattcc tgttcatccc gcttgcctct
     7981 cgcttcaaat taaccgaagg gatagtagta aattcggttt tggtcactca ttatttagtg
     8041 gaggaaaaca tgtcttggca gctgatcggc aatgaagcgg gattaatggc gattggatta
     8101 gtatttgctt tgcttgcaaa tgtttacatg ccagatcgta cgaagcagct gaaggaaaac
     8161 caaatacaga tcgaaaaaga atttcgaaat attttgagac aaatggcaga atttctttta
     8221 tcagaaaata aagaagatgt gcagatcaaa tgcgaacatt tactgacatt cattcgcgaa
     8281 agccaagaag atgccagaga acatcaagaa aactactggc tcagacagcc gctatactac
     8341 gaaacttact tctctatgag aagagcacag gccaatgtga ttaaagacat gctggaaaat
     8401 ctagagagaa tccagcaacc agcttattat ggaaaacata tctatggttt attgatttat
     8461 actgcagaaa cattttcaga gtcaaatgat ggcagacaaa ttttaacacg tattgaagaa
     8521 gtttatgtat tgtatcggca aatgcctctg ccgactagtc gccctgaatt cgaggatcga
     8581 gcagaattgt tccagttttt gcagtctttt aaaagtttta ttgaaatcaa ggcagaattc
     8641 tcccaacaaa aaatccaaaa atagaggttg tgaattcagc taatattcag gtcaaaaagc
     8701 tgatttcaca acctcttctt taaacggtgt tctcctgtca actcctcggt cacaagtcac
     8761 aatattcaac aaacatgaga agctgttttt tgaaattgct ccttgtgact cggagctgaa
     8821 cggtaggctc acaacctctt tcttaaacgg tgttcaaaag ctttcctctg cggtaataag
     8881 tccagccaaa cgaaaaatag gaggagctat ttttgtttgg ctgttcttat tacttgatgc
     8941 agaacagctt tttcacaacc ttttaaaatt acatattttt ccatagaact tgcatttgat
     9001 ccaagatttc gatgacatct tttgtcaaga agagagagcg attgggcaag tcaccttcaa
     9061 tcatgtgtac catattcttt atttcgtaat tcattgcttc agatgtattc ccgctttcga
     9121 tgaattcctt tgtaccatct gtaaataaga tctccgcacg atcagcacgc gggtaatcag
     9181 caatcgtcac ataaccgttc tcaaaggcaa cgataccgac ttttggcatt tttgcctgaa
     9241 aagtcaagct gacagcagca agttcatttt ctttgttacg caagatagtg acggattgtt
     9301 cgtccacgcc tgtttcaaaa ggaaccattg tagaggcaac tacttcaggt tgagagctca
     9361 aaaagaaacg agcgaaagat acagcatacg taccgatatc caacagagct cctccagcta
     9421 attctggatt gaagaaccgg tttttagggt ctggttcttt gtaactgccg aaaggtgctt
     9481 ggatcatttt taaagccccc agttttcctg tatccattat tgagcgtaac tgctgataaa
     9541 gtggcatgtt gaagattgtc atcgcttctg ctaagatcaa attcttttct tctgctaagc
     9601 gcatagcgtc agccagttct tttttattca tcgtgatggc tttttcacat agaacgtgtt
     9661 tgcctgcttc caatgctgcc aagatatggt cgatatgctg tctatttggt acagcaatgt
     9721 acacgatgtc gatttcagca tcgtctaaca tttcttgata gcttccgtaa gcttttggaa
     9781 tattgtaacg gtgagcgaag ttttccgctt tttctgaagt tctggaagca actgctgtta
     9841 gttcgctcgt ctcttgattg aagctttcgg caaactcatg tgcgatggta ccaagaccaa
     9901 cgattcccca ttgatatttt ttcatctgaa aacgctcctt catagttgga ttgagtttct
     9961 tgtctgtcta ttattataac aaaaatcacg aagaataaag aggagaggac ttgaaacatt
    10021 aaaaaaaatg aaagcagcga tttaagaggt gctttttgat caaaacttaa gtagaatagt
    10081 taaaaggagg ggataaacgt gcatcaagta tatattgatc ttattatgag tgtattatta
    10141 gaacagtttg aaactgaaaa aaatttttta gatgaatact tgctgatcag tccagaacaa
    10201 tggcaaaaat ggaaagatgg cgagaaaaat ctgccatctg aagcgatgca gaaagtaaaa
    10261 aatcttttca ctgattatga atggatgcta acgcaaaaga ttttgcgtca aacgattatt
    10321 tttcccgaaa aacgaaacgt tgccgttgca gagtacaagc aaatcaaaac acgcatcgcg
    10381 caaaaatggc ttagcagcaa agcagcaaaa gtcgagctga tccctttgaa aaataatcag
    10441 caggctggta gataccttga cttgaaagta agtattcaat atgatgaatg gggctatgat
    10501 gatattttga attttcgtct gccagcagat gttcaaaaac agatcgaagg agaaaaaatc
    10561 gaacttctcg attgggtgaa tgaaaatctg gaagaaactt acgttcatga ggcgaatggg
    10621 gaacgtgaag aacaacgaaa ggatttttca agtgaataaa tttttaggat ttggagcagt
    10681 tgtgattatg atcgcagcaa tgggctatgt tatttttagc gatgatgatt cgcatgttca
    10741 agccggcaat caagcagtcg aacgaacaag caccaaaaca actgctagta aagaaaagaa
    10801 cagtcaaaca accagcagca aggtaaagga caaagaaaca aaagatcgta cgtccaaaca
    10861 attgccagat gttaaaacag acgattggaa gctagttttg gttggtccag atcacaaatt
    10921 agaaaaagaa attgatgagt ctactcaatt ggcatcatta agtaacggat acttgatcga
    10981 caaacgcatt gctccagaat atgaagcatt tgccaaggct gctgaagcag ctggatttcc
    11041 attagtgatg gtctcagctt accggtctgt atcatcccaa caacaagttt tcgaacaaaa
    11101 tgtccaagat gtgatgagtc gtcaaggtgt atcagaagag gaggcgacaa agattactaa
    11161 agaaacgatt acggagccag gatacagcga acaccacaca ggtctggcag tcgatgtcgt
    11221 cgatcaaaac tggtacaaca gttatccttc tactgtattg gatgcaagtt acggagatca
    11281 gcctggagct aaatggatcg cagataatgc tgcgcagtat ggatttatcg ttcgttatcc
    11341 aaaaggacac gaagatataa ctaagatcac atatgaacct tggcacttac gttatgtcgg
    11401 taaagaaaac gctgagtata tcaccaaaca ccaattgacg ctagaagaat atctgaatga
    11461 attaaatgaa aagtaggaat tgatcatggc gaaaaaaaag tggaaaaagc aaaagcgcaa
    11521 gaatatccgt tggccagcag tggttgccgg tgtagcagtg atactcttag cctttgtttt
    11581 ttccttgaag aatctgtctt ctccttttac tgataatcag caagaaaatg aagcgcaatc
    11641 ccatcagcaa tttattgaac ggcttgttcc gcatgcccaa gaactacaag atggttatgg
    11701 agtgcttcct agtatcattt taggacaagc tatattagaa tcaaattggg gaaaaagtac
    11761 cttggctagc aaatacaata atcttttcgg gatcaaggct tatggggatc agaagaaagt
    11821 aagcctggaa acaaaggaat ttgttaacga agaatggata actatccaag gagacttcaa
    11881 agtgtatgat tcatgggaac agtccatgga tgaccataca caactgttcg tccaaggagt
    11941 agattggaat cctgcgctgt atgaaaaagt gattacggcc accaactatc aggaagccgc
    12001 acaagcattg caagatgcag gttatgcgac agaccccggt tatgcgcaaa aaatcatcca
    12061 ggtcatcgag acgtatcaat tgaatcagta tgaccggaga tagcaaagga gaagtggctg
    12121 atggcagaac aatttacgcc agaaatcatg acggaattga gaaaagatat cgtaagagta
    12181 ccggaaatca ttttagaagc aagcgggatc aagatatttg gaaaattgat ccgttcgatc
    12241 atctttacta cggatattgc gatcatacgt aatacaaatg cgaatgcagt aattgctgtg
    12301 tatcctttta cacctcatcc agcgattact aaaagcatta ttgaggcagc tgacattcca
    12361 gttttctccg gtgtaggtgg tggtttgaca caaggtgctc gttcttccta catgagcatg
    12421 ttcgcagaag cgcaaggttc gttaggggtc gttttgaacg gtcctacgcc tttagagaca
    12481 gtaaaagaag tttgtcgagt agttgatatt ccagttatca gtacggtaac gtcgaaatat
    12541 acagaaatag atgaaaagtt agcagctggt atttcgatta tcaatatcag tgcaggtaaa
    12601 gaaactgcag aagcagtacg ccattttcgt aaaaaatatc ctgaacttcc tatcattgcg
    12661 acaggtggtc caacggaaga aagtattgct gagaccattc aagcaggagc aaatgccatc
    12721 acatatacgc caccaagtag cggagagctt tttagtcgta aaatggaaaa atatcgggaa
    12781 actgagaaaa agaatcatga ataacaggtg agaatcaaaa gacgaggaag agcagatagt
    12841 ggctcttcct cgtcttttgt actccagtac tatttgttca gaattcaaaa aaaagagaaa
    12901 tttttttgtt tttttacctg taatgtacat aagaagagtt aaaacctttt gttattatta
    12961 gcattctaac aaaaaaatgt cttgatttat tgaagcgctt tctatagaat gaaaaacgaa
    13021 taaaaactaa aaaaggcacc cgacaattta gtagcagcta aattgtcggg gcttgaaaag
    13081 tcagcgggaa ctgaccaatc aagttgccat agtcaatgct tgtgcatcga cgtgtatatt
    13141 gtacctaatt tcatacagaa ttactagtta tttttctgtt ttttagggaa gagcgcacac
    13201 gaagaagcat gcttatttag ctatgtcaag gatattgggc agttgtctga tatccttttt
    13261 tctttgcgta attatcctcc catcattgaa gcaagaagtg tttttagcga tgaaagaaga
    13321 atcagcacta tctaattttt cttgaaagta ttgagttgtt catcctaggc agaacgataa
    13381 ggcaagtctt ggtttttatt ccccttgaaa aagatcgttt aataaatatg ttctgtataa
    13441 aaatacagta tattgaaaaa taacaatgga agtagaggtg cagagaatga agaaaagaat
    13501 gagaatcatc ttagctttaa gtgttatgtt attcttcttg acggcttgtg ggcaagaaga
    13561 tgacaaaaaa atcacgctga acatggcttg gtggggttcg caagtccgac acgatgcaac
    13621 agtaaaagta atcgagcttt atgaagaaaa aaatccccat gtgacgatcg attatgaatt
    13681 ttatgattat gaaggatatt acacaaaatt aggtacacta gcagcatcag atgatatctg
    13741 ggacattttc caactgaaca atcaatttcc tcaatacatc aatcagattg aaccattaga
    13801 tgaatatgtg gagcaaggga taattgatat ttctaatgca gatgaatcct atttagcaac
    13861 gacgacttac gacgggcaat tagttggact gtctaacggg gtgaattcgt ttgcgattgc
    13921 ttacaataaa aatatatttg aacaattaaa tatccctgaa ccagcttcaa attggacatg
    13981 ggatgaattt gaacaaatca gctatcaaat cactgaagaa ttaggaatct atgctatttc
    14041 aagattcgaa gattttatag ctggctgtat tattcaaata ccacaagttg agaaaggatt
    14101 gaatttttat aatcgggaag atctatctaa cagcttggga tttgaaaatc cagactatct
    14161 aacagatttt ttccagctgc gtaaaaatct ggtagacaaa ggggcccatc cagaaccagg
    14221 tggtggagct gcaagtacga cggatctgtc ttttcaggcg gttagggata gagaagcggc
    14281 aatggtgttt ctatcaagta accagttgac agaaatattg tcaggggctc ctgaagatat
    14341 ggagattcag ttgattaatc cacctcgcag aaaagcagat ggagaatctg gtatcccttt
    14401 acgttcttcg caaatgctga gtatggcaaa aagctcagcc cataaagaag aagctgctaa
    14461 gtttattgat ttctttcaaa acagtgaaga agccaatgaa attttaaaag gagaacgtgg
    14521 tgtaccaatc atgtcgaata ttcgagaaca gctcgctcgt gcagatgatg caactttgca
    14581 agcgacattt gattatttag aaatgatttc cgatatggac aacggcgaag tgaatgtctt
    14641 tgatagtgct ttgaatccgg aaattcaaga ccaatacaat cttttagttg aaaaagtcat
    14701 ttatgaagaa gtaacagcag aagaagcagc agagagtctt tatgagtttg cgtcaaacat
    14761 tctaggatag cagcaggagg aaggcatgaa aaaagaaaaa ctaaaacggt tcttggatca
    14821 agacaatgtg gtcggttacg tatttgcttc tccattcatc ctaggatttc tattgataac
    14881 agtgataccg atgatcttgt cactttatta ttcgttcacc gattatcgtt tgggaaatcc
    14941 agtctcatgg atcggcttgg ataattatat aaagatgctg agtgatgccc gttttttgaa
    15001 ctccatccga gtcacttttc tctatgtatt tgcatctgta cctgtgaaac tgatctttgg
    15061 tctattgatt gcttatcttt taacgaggaa tatcaaagga acgactttct ttcgttcttt
    15121 gtattatgtg cctagtttga tcggtggcag tatttctatc gctctagttt ggcgggagtt
    15181 gttttctaaa aacgggttag tgaatatttt cctggaacga ttaggcgcac ctgcgctttc
    15241 ctggtttagc gatcaaaaac tggtcatgat ccctcttgtt ttgatgtctg cttggcaatt
    15301 cggttcggca atgatcatct ttgctgcagg tatcaaagag atcccaggct cgtattatga
    15361 agcggcagag atcgatggag cgaacaaatg gcagacgttt tacaagatca cgttacctct
    15421 tctttcgccg atcattttgt ataacttggt tatgcagaca atcgcggcgt ttatgacttt
    15481 tacgcaggca tttatcatta cccaaggtgg tccgaatgat gccacgaact tttatgctct
    15541 ttatgtgtat aaccaagctt tttcttttaa ttctatgggg tatgctagtg ctatttcgtg
    15601 gatcatgctg ttgattatgg gagctgtcac ctttctgatt ttcaaatcat caaaaaaatg
    15661 ggtcgttgtg tgaatgagag gaggaagaaa tgaataatac agtaacgaaa tggtttcaat
    15721 acggttttat tttgctatta ggtctagtca tgatttatcc ggtcttatgg atgatcgcag
    15781 gttcttttaa aacggatcaa gagattatga gtggttcgct gaatttgatt ccagagactt
    15841 ttcaatggga aaattacgca aaaggatggg cggggtttgc tggaatttca ttttttactt
    15901 tctttaggaa ttcgtttgtc atctctgcag tttcgacgat agggacagtt ctgagctcga
    15961 cttgtattgc ttacgcatta tcgagaatcg atttcaaagg aaaaagattc tggttcgtcg
    16021 tcatgttagt aacgatgatg attcctgcac aagtgatttt gattccgcag tttattattt
    16081 acaatcggct gaatttggtt gggacgtatg tgccgctgat tttaccacat ttttttggac
    16141 aagcattttt catttaccag atcatgcaat tcatggtcag catccccaaa gagttagatg
    16201 aatcagcgat tattgacgga tgcagcaagt atagtgtctt taccaaaatt atttttcctt
    16261 tgctgaaacc ttcgatcatc acgacgatca tcatccagtt ttattggaaa tgggacgact
    16321 tcatgggacc attgatttat ttaaacaagc cgagatctta cacggtatcg attgccatca
    16381 aattatttgc agacgctgga tctagtacga cttacgcgag tatgtttgcg atgtctacgt
    16441 tgtcgctgct accggttttt ctgattttct tattcttcaa taaatatctt gtccagggga
    16501 tcagtacaag cggtctgaag ggctgaatat gaaaaagcca atagaagaga tgtttcttta
    16561 caagctcaac tactatgtct gtcggatttt tttaaccagt cttatcagta atgctctttt
    16621 cgctttagtt ctaggatgtt tgttcacttt aggattagtg ctgtctgctc gtgttgtcta
    16681 tctgatttat tttttgatga tgtatccttc ttattatcta tctgtccatt acttggcaga
    16741 aaaaaaggta tgttggagga aaggaaaaat caaacggatg tgtttcatca ttacgttgtt
    16801 tcagctgttt gtcattattt ttgcagttga ttggtattta ttagtgggaa agattggagc
    16861 ttggtatctg attccttttc tattgtgtct gttgcttttt gtatcccata gtttttttag
    16921 tacgctaatt gatatctgca aagaagataa agcagatagt cttgtttatt tgatcaaaag
    16981 gaatatctgg ctgttgtcaa aaaacgtcaa ggggtttctg tggtatttat gccttttgta
    17041 tggactgttc tggtgtatac agcatgattt tttactcact gcattactgt atccagggct
    17101 gccatttgtc acagtatttt gcttaaaaga aaaggagaat gactttaaat gaagaaaaaa
    17161 tatgtacaag tcggacttgg tgggagagcg cgtttttttt atgaggcaat tgcctctacg
    17221 tatcatcaaa cttgtgaact agtcggtttt tgtgatgtat ctcaaacaag gatggattat
    17281 gcaaatcgga tacttgtgaa caagtatgga cagaaaaaag taaagacatg tatgccatca
    17341 caatttgagc aactactgga tgacgtacgg ccggctgaag tcattattac gtcagtagat
    17401 cgaacgcatc atgattatat cattcgtgca atgaaaaaag gatatgatgt tatttgcgaa
    17461 aaacctctga ctatcgatga ggaaaaagct caagaaataa taacggtcca aaaacagacg
    17521 ggaagaagcc tgcgagtcac ttttaattat cgttatgcac cgtatcacac gaagataaag
    17581 gaactgatag aaagtgatgt gattggtgat gtgttttcta tccacttcga atggctgtta
    17641 aatacgcaac acggggcaga ttatttcaga agatggcatc gaaataagca caatagcggc
    17701 gggcttcttg ttcataaatc tacccatcat tttgatctag tgaatttttg gttgaacagc
    17761 cgtccccaaa aggtatttgc attcggtgga ttaaactttt atgggatgca taatgcggag
    17821 aaacgcggag tagaaatatt ttacagtcga tgctatggaa gcgaactagc taaagctgat
    17881 ccatttgcta tagacctgtc agccaatgag gaattgcgag aaatgtattt agaagcagaa
    17941 aaagacagtg gatatattcg tgaccgcagt gtattttccg atgatatctc tattgaagat
    18001 acactaggcg taacggtcaa atatgaaact ggtgcgattt tgacgtattc gctaaacgcg
    18061 tatatgccgt gggaaggatt caatgtttct ttcaatggca gcaaaggacg gatcgaaatg
    18121 aaagtgatcg aaaagtctta catcaatgca ggtggagata aaaaggatga aggagcagcc
    18181 gttcttcagt ccatccatgt ctatccgatg ttcggtgagc catatgaggt aatcgtcgaa
    18241 caagaagcgg gcggacatgg cggaggagat ccgcgtttat tagatgatct atttggtgaa
    18301 gaaaaagaag aagatccgtg gaatcgggca gcaactcacg tagatggtat tttgtcgatt
    18361 ttgacaggaa tcgcagcaaa tcattctatt gcttcaggaa aagcagtagt gattgacgag
    18421 cttgtcagct taaaagaata agaatagatt tacggaaatt acttcccgta gtttataaaa
    18481 tcttgcctta ttgccgatag gctgtctttt gaacactatt tattcggaaa aaggggctat
    18541 gacatgcttt ttgtcatgcc ttctttttat gtgggctgct tttttagata ggagaaaata
    18601 aaaataacta tttaaacccg aacaaaaagg aataatgcat taaaaatcat tagattttac
    18661 aaaaaaataa gtaaaccacg ttgtcagttt cagaaagtag tgttagactg ttttcaatat
    18721 ttgaaacaac attttttatt caaatatggc aaactgcctt cacgtgcaaa acagttgcaa
    18781 gaaaatgaat ttacactatt attagtttta catacctact tatatatcgt cataatatgg
    18841 atgacagttt ctagccagta ccgtaaatgc tggactataa gtaaaagatt ggctatttca
    18901 cccttctttt cttatgataa agtggagggt gtttttcttt aacagaaaca tagtaggttt
    18961 ttgcacaaaa gcggttattt cggtattaat aaatgataaa ggagcaaata aagtgaaaga
    19021 attagttgaa cgtattcaaa aagacggacg tatattaggc gagggcgtat taaaagtcga
    19081 cagcttcgtc actcaccaag tagaccctgt attgatggaa caaatgggaa aacggtttgc
    19141 agaagtattt aaagaacaag gaatcacgaa agttgtgacc attgaagctt ctgggatcgc
    19201 accagcttta tttgctgcaa gagaattaga tgttccaatg atcttcgcta gaaaagcaaa
    19261 aagtttgacg atggatgaag aattattgac agcttctgtt tattctttta cgaaacaagt
    19321 gacaagtacg atttctattt ctcgtaaatt tttatcttca gaagacaaag tattgattat
    19381 cgacgatttc ttggcaaacg gacaagcggc aaaaggattg atcgaattat gccagcaagc
    19441 tggagcgcaa gtagaaggaa tcgggatcgt catcgaaaag tctttccaag atggacgtca
    19501 gttacttgaa gaaatgggat tgagagtcgt ttctcttgcg cgtattgctt ccttgacgaa
    19561 tggacaagtt gagtttcttg aggaggacgc ataatcgtgg aaaaagaaac acaaaatgga
    19621 aaagctgcgg ttttagggct gcagcatctg ctagcgatgt atgcaggagc agtagcggtg
    19681 cctcttttga tcggtacagg actaggcttt aatcaagaac agatgactta tttgatttca
    19741 attgatatct ttatgtgtgg attagcgaca ttattgcaat tgacagttaa ccgatttttc
    19801 ggaattggct tgcctgtcgt tttaggatgt gcgatccaag cagtagctcc actgatcttg
    19861 atcggaacca atgaaggagt aggagctatc tacggatcta ttatcgcttc tgggatcttt
    19921 gttgtgttag tttctggtgt cttttctaaa attaaaaaac tattccctcc tatagtaaca
    19981 ggaacggtta tcaccgttat tggtttgact ttgattcctg tagcaatcga gaaaatgggt
    20041 ggaggtaatg caacagcagc tgattttggt gacaaaacaa atctgctact tgcatttgtg
    20101 acgattctcc taattgtagg cgtgcaaatg ctggcaaaag ggttcattcg ttcaatcgcg
    20161 gtattgattg gtttagtcgg aggaagcatc ttagctgctt tcatgggaat gattgatctg
    20221 agcgcgattg gagatgcgcc gttgttccat gttccacaac ccttttattt tggtaaacca
    20281 actttcgacg tatggtcgat tttactaatg atcatcattt ccatggtcag catggtagaa
    20341 tcaacaggtg tatattttgc acttggtgac attactggga aaaatgttgg agaagaagaa
    20401 ttgaaaaagg gatatcgtgc agaaggactt gccgttatct taggcggtat tttcaataca
    20461 ttcccttata ctggcttttc tcaaaatgtc ggattggttc aactttcggg aatcaaaaca
    20521 agaaaaccca tctatttctc tgcattcttc ttgattgttt taggattatt ccctaaaatc
    20581 ggtgcgttag cacaaatcat ccctgagccg gtacttggtg gaggaatgtt agtcatgttc
    20641 gggatggtgg cagtccaagg aatccgtatg ctgttggaag ttgatttcag caatgataaa
    20701 aatctattga ttgttgctgt ttctgttgga tttgggctgg gtttcaatgt tacgccgaca
    20761 ttattcagtc aaatgccgca aacattgcaa atgttcactg gaaatggcat cgtaatgagt
    20821 agcattacgg ctatcatatt gaatttgatc tttaatggat tgaaaaaaga tgaagaaata
    20881 ttggaagaag ccttcaagaa gtaatagagc aaaagaaagg ttgtgaaatc agcgttttga
    20941 cctgattgtt agagaaacaa acggaaaaat agttcctcgt attttgccgt ttgtttgagc
    21001 taataccgag ggtcagctga ttgaacaccg ttgaaggaag aggtcgtgag cctgccgttc
    21061 atctccgagt cacaaggaac aatttcaaaa aaaagcttct catgtttgtt gaatattgtt
    21121 ccttgtgacc gaggagttgg caggagaaca ccgtttatcc ataaaaagga atgtgaccta
    21181 acttttgtca cattcctttt ttttatcttt aataaacacg aacaataaaa tgtttttctt
    21241 tgttaacatt cgaaatttct ttgacatcaa aaaaagtgat tgttaaaata tgaatgtaga
    21301 aaaactggga ggaaaaacaa tgacagcaaa aatctctgtg attatgggga gtacttcaga
    21361 ttgggaaaca atgaaagaag catgtcaaat attggatgaa ttcggtgtgt cttatgaaaa
    21421 aaaggtcgtt tctgctcatc gaaccccaga tttgatgttt gaatatgcac aaaacgctcg
    21481 aaaaaaagga atcaaaatca ttattgcagg agcaggggga gccgcgcatc tgccgggtat
    21541 ggtcgcatca aaaacaactt tgccggttat cggtgtaccg gtccaatcac gaacattaaa
    21601 tggtttggat tcgcttcttt cgattgtcca aatgcctgga ggagtacctg tagctactac
    21661 agcaatcgga aaagcgggag caattaatgc tggactactt gcgatacaga tgctttccat
    21721 gtatgattta gaattggagg ctaaattggc tgaaagacgt tcaatgttgg ctaaaactgt
    21781 tatagaaagt agtgatcaac ttggttaaac ctttgttgcc tggttcaacg atcgggatcg
    21841 tcggtggcgg tcaattaggt cgtatgatgg cgattagtgc aaaagaaatg ggctttaaag
    21901 taggtgtgct ggatcctgtg agcgattgtc cagccgcaca agttgcagat tggcatattg
    21961 aaagtgtcta tgatgacacc tttgcgctga aagagcttgc cagaagaaca gatgtcatta
    22021 cctatgaatt cgaaaacgtc agtgtagagg cgttaaatgc gattttaccc atgtcattta
    22081 ttcctcaagg gacagacttg cttgcgatta cgcaagaccg cctgttagaa aaatcttttt
    22141 tggaaacgaa taacatcgtg attgctcctt atgcaacgat cgtcagtccg acggatatcc
    22201 aagatgcgat tgacgggatc ggctatcctt gtgttttgaa aaccactcga ggcggctatg
    22261 atggcaaggg gcagtatgtt ttgaaaagtc gggcggatct agctcctgcc atggaccttt
    22321 taagagaagg aacctgtgtt ttagaagcat ggatcccgtt tgaaaaagag atttcgatca
    22381 tggtggcagg aaatggtcaa ggagatttca cgacttttcc ggtcgtggaa aacatccacc
    22441 acaacaatat tcttcatgaa acgattgctc cagccgcgat tgatcaggat gtgatcgagg
    22501 aggctgagcg tattgcccgt gtgattgcag aagcagtgag cctttcaggt gttttagggg
    22561 tagaaatgtt tttaacaaaa acaggcgggc tatatgtgaa tgaattagct cctcgtcctc
    22621 acaattctgg acattattct attgaagctt gttctatgag tcagttcgat gcccatattc
    22681 gaggtatttg tggttggcca ttaggagaaa aagtacgttt gataagcaat gcagtaatgg
    22741 tcaatgtttt gggagaacaa ctgctggaaa gctatcgctt gattgagaat aagccagact
    22801 ggcaattcca tttctatgga aaaaaacaag caaaaaaagg tcgcaagatg ggacatatca
    22861 ctatcttgac agaagacatc cagcaaacgc tggaagaaat caaacaaacg aatatttggg
    22921 attagaggag aaaaaacatg ttagaacgtt atacacgccc tgaaatgggg aatatctgga
    22981 cggaagagaa caaataccgt gcgtggctcg aagtcgagat tttagcagat gaagcttggg
    23041 cagaacttgg tgaaatcccg caagaagatg tgaaaaaaat tcgtgagcat gcatcatttg
    23101 atatcgatcg gatcttggaa atcgaaaaat taacacgcca tgatgtcgtt gcgtttacac
    23161 gagcggtttc tgaaacattg ggagaagaaa gaaaatgggt ccattatggt ctaacaagta
    23221 cggatgtcgt agatactgct tatggctatc tcatcaagca agcaaatgat attttacggg
    23281 aagacttgaa acgttttacg gaaatcattg gcgaaaaagc aaaagaacac aaatatacag
    23341 tgatgatggg tcggacacac ggtgtccatg ctgaaccaac tacttttgga ttgaaacttg
    23401 ccacatggta ttcagaaatg aaacggaaca tcgaacgatt tgaacatgcg gcaaaaggag
    23461 tagaagcagg aaaaatctca ggagcagtgg gaacgttcgc aaatatcccg ccatttattg
    23521 aagagtatgt atgtaaacaa ttggggatcc gtccacaaga aatttctact caagttctcc
    23581 ctcgggatct acatgctgaa tatttctcag cgatggcgct tattgctaca agtattgaac
    23641 gttttgcaac agagatacgc ggattgcaaa aatccgaaac acgtgaagta gaagaatttt
    23701 ttgcgaaagg tcaaaaaggt tcttctgcta tgccgcacaa aaggaatccg atcggttcag
    23761 aaaatatggc tggtctagcc agagtggtgc gcggacacat ggtcactgcc tatgaaaatg
    23821 tcacattatg gcatgaaaga gatatttctc attcttcagc agaacgaatc atcttgcctg
    23881 ataccacgat tttattgaat tacatgttaa atcgttttgg caatatcgtt aaaaatctaa
    23941 cggtctttcc tgaaaacatg aagcggaata tgtctgcaac atttggtttg atttatagcc
    24001 agcgcgttat gctgaaattg atcgataagg gaatgacaag agaagaagct tatgatcttg
    24061 ttcagccaaa aactgcgtac gcttgggaca accaagtgca gttccgcccg ctgttagaag
    24121 aagatccaac catcacatcg gtattatcta aagaagaaat agacgatgcc tttgattatc
    24181 atcatcattt gaaaaacgtt gacgtgatat tcaaacgagt aggtttggaa taaagaagag
    24241 tgagttgcaa aattcaatta aaatagaata gcaaaaataa ccaaaaaaga agcagatccg
    24301 ttagcggttc tgcttctttt agtttattat attttcttat caataatagg aacctgattt
    24361 taaaagcggc tacctcttta ccgtgcctct ttacatacaa aaaatagagg aattaagcgt
    24421 aaatggcttg gctattataa ctaaaatgct ggttatggag atgttgcagc aagttttcga
    24481 gaaaagcgta ttccatctct tgtccattga ataagatctg gatacgataa tgatttttga
    24541 aacgcttctg ttcatgaatc tgactgattg aaagttcgcc tttgtgttct gtctgataaa
    24601 gaaaagtcct tttacggcat tcagcacagc gcttggttgc tcggcggatt tttcggaatg
    24661 tataaaaact agtatcttta ttgcataaat aaacgtcttt gatcgacagc aaatcattat
    24721 atagacagga acgttcttca gctgttaatt ctgataaaaa aagctgacct tgttttattg
    24781 catcttccat cggcaagtgc ctcctcgaac ccattaacca aatttttagt taattctaat
    24841 ataccatcat taagtataaa tgtaaacgct tgttgatggt ataagatttt cgtttctgat
    24901 aaaacacgaa cattaaaaga atctaatgcc ttaaatgtac atatttttgt tgatttataa
    24961 aaagatgatt gctaaaattt aaagtgaaaa aacgaacaaa aaacgatgta tttgctttta
    25021 atgtaaataa aaaggagaga cgtacatgga gaagaaagaa cttttgtatg aaggaaaagc
    25081 caaaaaaata tatcttactt ctgatgagaa cttgatttgg atagaatatt tagatcaagc
    25141 aactgcgttg aatggcgcga ggaaagacca gataagtgga aaaggagaat tgaataatca
    25201 aatcacaagt gcaattttcc gttatctgac tcaaagagga ataaaaaatc attttattga
    25261 acaattgtct aaaaccgaac aattagcaaa aaaagtacaa attatccctc tggaagtggt
    25321 tatccgaaat attgcagcag gaagtttctc aaaacgtcta ggtgttcccg aaggtaaaga
    25381 attcatcaaa ccaatcattg aattctacta taaggatgac cagttggatg atccatttat
    25441 caatgaagag catatctatt tcttacaact tgcaaagccg gaagaaatca gtgagctgaa
    25501 agcccaagcg ttggctatta atgaaatttt gaccgaatta tttgctaagg tcggtttggt
    25561 tttagtagat ttcaagctag aatttggccg gtcgaatgga caaattttgc ttgcggatga
    25621 agtaacaccg gatacttgcc gattatggga tgaacgtacg aatgaacata tggacaaaga
    25681 cgtttaccgc agagatctag gtgatttgat cccagtctat caagaagtat ataaccgtct
    25741 atcggaacta actgaagaaa aggagcgagt atgatgtatt tcgtaaaagt atatgtaacc
    25801 tataaagatt cagtgttaga tcctcaaggg gaggcagtaa aaaaagcagt ccatcgtatg
    25861 ggatatgaaa caatcgaaga tatccgaata ggaaaatact ttgagataca acttgctgat
    25921 gcagaagaac caatcgatac agtgattgaa acgatttgtg acaagctgct tgcaaatgta
    25981 aatatggaaa cataccgata tgaaatcaaa aaaatggagg aagtataaca tgaaatttgc
    26041 ggtcatcgtt tttccaggtt caaattgtga cgcagatatg ttatgggcag ttcgcgagat
    26101 catgggcgct gatgccgaat ttgtacggca tgatgagtcc tctttagaag gatttgatgg
    26161 ggttttactg ccgggaggat tctcctatgg tgactatttg agatgcggtg cgattgctcg
    26221 gttttctaca atcatggaag aagtgattcg ttttgctgaa gaagggaaac cagtattcgg
    26281 tacatgcaat ggattccaga tattgacaga agcaggactt ttgccaggtg tactgagacg
    26341 aaatgagtct ttgcatttta tttgcaaaac tgtaccattg aaagtcaacc ccaagacggc
    26401 ctttacttca gagtatgaag ccgacgaaat aatctatctt ccagttgctc atggggaagg
    26461 aaattatttc tgtgacgaag aaacacttca agaactaaaa aaaaataatc agattgcctt
    26521 tacttataat gacaacatca acggcagcgt ggaaaacatt gcagggatta cgaacaaagc
    26581 agggaatgtg ttaggaatga tgcctcatcc agaacgtgca gtagaagact tgctaggatc
    26641 agaagatggg aaacggttct ttgcttccat tttaaaaaac ttcggaaagg tgaccgtata
    26701 gatgaaaaca ttgaaagaac cgacagctga agagatcaag aaaaaaagaa tctatgccga
    26761 atggggattg actgatgaag aatatcgaat gatcgaagaa gatatcttag gaagaatgcc
    26821 taattatacg gaaactggac tgttttctgt tatgtggagc gaacattgtt cctataaaaa
    26881 ttctaaaccg gttctacgca aatttcctac tagtggacct catgtgttgc aaggccctgg
    26941 agaaggcgca ggcatcgtcg acatcggtga tggactagca gttgtcttca aagcagaaag
    27001 tcacaatcat ccttcagccg tggagcctta tgaaggagct gcgacaggag ttggcggaat
    27061 catcagagat attttcagca tgggggctcg tccaattgcg ttgctagatt cattgaggtt
    27121 cggcgaatta gataatccaa gaacgaaata tttactagaa gaagtagttg caggtatcgg
    27181 cggatacggc aattgtatcg gcataccgac tgtaggcggc gaaattgcat ttgatccttg
    27241 ttatgaagga aacccattag tcaatgcaat gtgcgtaggt ttgattgaac acaaacatat
    27301 ccagaaaggg caagccgctg gcgtcggtaa ttcgatcatg tatgtaggtg caaaaacagg
    27361 tcgcgacggt atccacggag caacttttgc ctcagaagaa tttaatcaag aagaagaaca
    27421 gcaacgttct gctgtacaag taggcgatcc ttttatggaa aagctgctgc ttgaagcgtg
    27481 tttggaatta atcttgcatc attcggattc tctaataggt atacaggata tgggagcagc
    27541 aggacttgtt tcatctagtg cggaaatggc ttcaaaagct ggctcaggac ttatattgac
    27601 attagatgaa gtcccacaaa gagaaactgg gatgacacct tatgaaatga tgttatcgga
    27661 atcacaagaa cggatgttga tttgtgttaa atcaggagag gaagaaaaaa tccaagaact
    27721 atttcagaag tatgatctag atgcagtcac tatcggtaaa gtaacagacg acgggcaata
    27781 tcggctatat catcaaggag aagaagtagc aaatctgcca gtcgatgcat tagctgaaga
    27841 tgcaccagtt tatcataaag aaatgaaaga accagctcga atcgtagaat ttcagcagtt
    27901 agctccttat cagccagtta tcgaagaacc tggacaagta ttgcttgatc tgctgcagca
    27961 accgacgatt gcttcaaaac gttcaatcta cgaaacttat gattcacaag tacaaaccaa
    28021 tacagttgtc cgtccaggaa gcgatgctgc tgtgatgagg gttagaggga cgaataaagc
    28081 gttagctatg accacagact gcaacgcgcg ctatctgtat ttggatccaa aaatcggagg
    28141 acaaatagca gtggcagaag ctgctagaaa tattattgct agcggtggta agcccttggc
    28201 gatcaccgac tgcctgaact atggttctcc tgataaacca gaagtttttt gggaattatc
    28261 gacttcagct gacggaattg ctgctgcgtg tgaaacgtta ggaactcctg ttatttcagg
    28321 aaatgtctct ttatataatg aaacggatgg tcaagcaatc tatccaacac caatgattgg
    28381 tatggtcgga ttgattgagg atcataaaca tatcactact caggaattca aaaaatcagg
    28441 ggatctaatc tatatattag gtaagacgtt tgcagatttt gatggcagtg aattacaaaa
    28501 gatgcagctt ggaagaatcg aaggtgtgat ccgaaacttt gatctatcca ttgaaaagag
    28561 aaaccaagag ttagtattga cagccatcca aaacggattg attgaaagtg ctcatgactg
    28621 ttcagaaggt ggcttggcaa ttgcactggc agaatcagct ttcaaacatc agctagggat
    28681 atctgtacag tttgaattgt cctctgctca attatttgca gaaactcaat caagatttgt
    28741 gttgacagtc gcaccggaaa ataagacacg attcgaagaa atgatgggag atgctgctgt
    28801 tttagcaggt aaggtgacgg atgaagcgat aatcgaaatt tcagcaactg acggtcagat
    28861 caaaatagaa actgcagtag caagaaagtg ctgggaggat gcaatcgtat gtcttatgaa
    28921 gtgaagagtt taaatgaaga atgcgggatc ttcggtgttt ggggtcatcc agacgccgct
    28981 agtgtggcat acttcgggct ccatagtctt cagcatcgag gacaagaagg tgcaggtatc
    29041 gtgtccaatg atcgaggaaa gcttaagggg catcgagatt tggggctgct ttctgaggta
    29101 ttcaaagatc aaagaaaatt gcagcagtta acaggagaag ctgcaatcgg acatgtacgt
    29161 tatgcaacag caggcaatgg aagtgtggac aatattcagc cttttctatt caaatttcat
    29221 gatcagtcga tcggcttagc gcataatggt aacttgatca atgctcgttc ccttagaaaa
    29281 gagttagagg aaaatggggc gatcttccat tctaactccg atacggagat attgatgcat
    29341 ttgatccgac gaagtgaaga aacagatttt ttaaataaat taaaaagtgc tttgaatgaa
    29401 gtcaaaggtg gctttgccta tttattaatg acagaaacgg caatgattgc cgctttggac
    29461 ccaaatggtt ttcgtccatt agcaatcgga caaatgaaaa acggagcata cgtgattgcc
    29521 tcggaaactt gtgcattaga agttattggg gcacgtttta taagagatgt ccagcctggt
    29581 gagatagtga tcatcaatga cgaaggaatc cagattgatt gctttacgaa ggacacgcag
    29641 ctttctattt gttcgatgga atatatctat tttgccagac cagattcaaa catcgcaggg
    29701 atcaatgtgc atactgcacg gaaaaatatg ggacggaatt tagcgaaaga atcgccagta
    29761 aaagcagata tggtcgttgg cgtacctaat tcttctttgt cagccgcaag cggttatgcg
    29821 gaagctagtg gaatccctta tgaaatcgga ttagtaaaaa atcaatacat tgcccgaaca
    29881 tttatccagc caacgcctga gctaagagag caaggtgttc gaatgaaatt atctgctgta
    29941 cgaggagtag tggaaggtaa aaaggtgatt atggtcgatg attcaattgt tcggggtacg
    30001 acaagcagac ggatcgtcca tcttttgaaa gaagcagggg caaaagaagt ccatgtgagg
    30061 attgcttctc ctcctttgaa atatccatgt ttttacggga ttgatattca aacgcgtaaa
    30121 gaactcattg cggcaaatca cacgattgat gaaatcaaag aatgtatcgg tgcagattct
    30181 ttaggttttt taagtgaaga gggtctgatc gaatcgatcg gtctggaaaa agatgctccg
    30241 tattcaggat tgtgtatggc ttatttcaac ggagattatc cgacgccgtt atatgactat
    30301 gaagaaaaat atcaggaatc actaaaagaa aaagtatcgt tcttttaaaa gcagaccaag
    30361 aagggagtat atgaattcaa tggcaaatgc atacgcaaaa gctggcgtag atgtcgaagc
    30421 tggatatgaa gtagtagaac ggatcaagaa gcatgtcaaa aaaacggaac gtttaggtat
    30481 gatgggcgct ataggaggat tcggcggttg ttttgattta tcggtctttc aattaaaaga
    30541 gccagtcctt gtctcgggga ccgatggcgt ggggacgaaa ttagcagtgg caatcgaagc
    30601 agacaaacac gatacaatcg ggatcgactg cgtagcgatg tgtgtcaatg atatcttagc
    30661 acaaggcgca gagccgttat atttcttaga ctacttagca acggggaaaa atgatccgtt
    30721 acgtttggaa aatgtagtaa aaggtgtagc agatggatgt gttcaaggaa atatggcgct
    30781 gattggcgga gaaacagctg aaatgcctgg tatgtactca ggtaatgatt atgatctagc
    30841 cggatttgct gtagggatag ctgaaaaatc tcaattattg acaggagaaa cgatcaaccc
    30901 aggagatgtg ttgcttggaa tagcatctag cgggattcat tcaaatgggt actctcttgt
    30961 tcgcaaaatt ttctttgagc agcagcagtt ttctttatca tcaaaactgc cagaattgaa
    31021 aaaaacactt ggcgaagaat tgcttgagcc aacgaaaatc tatgtttctt ccttgcttcc
    31081 gctgatcaaa gaaaagaaaa taaaaggagc tgcacatatc actggtggag ggtttgtaga
    31141 aaatatcccg cgaatgttac cagaatctat ggctgcacaa atcaaacttg gctcatggcc
    31201 gattcttcca atattcggct gtttacaaaa atatggtgaa attcctgaga tggagatgta
    31261 tgaaatcttc aatatgggca tcggtatggt cctggcagtc gaagaatcga aagtaaaaga
    31321 aatagtacac gaaattgagc aagctggcga aaaagtttat gaaatcggga aagtgatcgc
    31381 caaagaaaaa catcgtgtgg tgtttatagg agaagaacga tgagaatcgc tgtttttgct
    31441 tctggaaacg gaagcaactt tcaagcgcta gccgattatc tatcgaaaaa aggattggaa
    31501 tcttcgattg actggttgtt ttgtgatcag cctgaagcat atgttttgaa acgtgcaact
    31561 gcgttgagtg taccggcaga ttgtttttca cctaaagaat ttgattcaaa aaaagagtat
    31621 gaagaagcaa ttttgcataa attgaaagaa aaaaagatcg atttgatcgt attagctgga
    31681 tatatgcgaa tcattggacc ggtattgctg aaaaattatg ataaaagaat catcaatatc
    31741 catccgtctc ttttacctgc cttccctggt ttgcatggca tacgtgatgc ctttgaagct
    31801 ggagtaaaag aaacgggtgt cacaattcat tatatcgacc aaggtgtaga tactggacca
    31861 atcatccggc aggaaaaagt gagaattgaa caggaggaca cgttcgattc tttagaagaa
    31921 aaaatccata gagtagagca tcgaatctat ccagaagtga ttagtgaaat tattgaaaat
    31981 ggaggctatc tgaaatgaca agagcattga tcagtgtatc agataaaact gggattgtag
    32041 cattcgccca aggtttgatt gaacaaggag tagaaatcat ttcaacagga ggaacaaagc
    32101 atgcgttgga taaagctggg atcaaaacgc tttcgatcga agaagtgaca gggtttcctg
    32161 aaatgatgga tggccgtgtc aaaacacttc atcctaaaat ccatggtggt cttttaggaa
    32221 gacgcgatct ccctagccat atggaggcaa tggaaacgga aaatatccaa ccaatcgact
    32281 ttgtttgtgt caatttatat cctttcaaag aaacgattat gaaaccagat gtcgaaatag
    32341 cagaagctat tgaaaacatt gatatcggtg gtcctagtat gctccgtagt gcagcaaaaa
    32401 accatgaatt tgtcacctct gttgttgatc catctgacta tgaagaagta ctttcagaat
    32461 tacgtcagta tgggcatact tcactttctt tcagacaaaa actagcggca aaagtctttc
    32521 gtcatactgc ggcatatgat gcactgatcg ctcaatactt aacggattgg gtggaagaaa
    32581 aagaaccgga aaaattgaca cttacgtatg aacgaaaaca aacgcttcgt tacggtgaaa
    32641 atagccatca agccgctgcc ttttatcagt ccgctcttct ggaaaaatat tcgatcgcag
    32701 cagcaaaaca actccatggg aaagaacttt cttataataa tatccgagat gcagatgctg
    32761 cgctacggat catgaaggaa tatgacgagc caacggtagt cgccttgaaa cacatgaatc
    32821 cttgtggtat tgggacagca tctacgattt tagaagcgtg ggaagcagcg tatgaagcag
    32881 atcctgtttc aatctttggt gggatcatcg ttttgaatcg agaagtagat ctgccaacag
    32941 cagaacagat gcataagctg tttctagaaa tcatcattgc cccttcttat acacaagaag
    33001 ctttggaatt actgcaaaaa aagaaaaaca tccgattact gacagtagac tttgcgcagg
    33061 aagaaaatca aaatcgagaa gaaacggtct cagtcttagg tggacttctt gtacaagatc
    33121 aagatctggc aatagaaaat gaagaagagt ggaaagtcgt gacaaaacgt aagccgactc
    33181 cagcagaagc aaaagcatta gtgtttgctt ggagagctgt caaacatgtg aaatctaatg
    33241 cgatcgtact ggcaaacgaa cgtcagacag taggaatcgg agccgggcag atgaatcgag
    33301 tcggttcagt aaaaattgcg attgaacaag cgcaagagaa aatggaaggt gcagttttag
    33361 ctagcgatgc ttattttcca atggatgatt cggttgaata tgcagccaaa catggtataa
    33421 aagcaatcat tcagccagga ggaagcatca aagaccaaga ttctattgat atggcgaata
    33481 aatacgatct agcaatggtc tttactgatg ttcggcattt tagacattag agaggagtcg
    33541 gataaatgaa cattttggtg atcggtgcag gtggtcgtga acatgcaata agtaaaaaac
    33601 ttttagccag tccgaaggtg gatacggtgt attgtgcgcc aggaaatccg gggatgacaa
    33661 aagatggtat caattgtgtc gctatcagtg agcgagatca ttcagcgtta atccattttg
    33721 ttaagaaaga ggctattgat tggagtatcg ttggtcctga agttcctttg ttaaatggga
    33781 tcgtcgatga ttttatggcg gaaggattga aaatcttcgg tccgacaaaa gcagcagctc
    33841 tgatcgaagg ttcgaaaagt tttgctaaac aattaatgga tacttatcaa atcccgacag
    33901 ctaaatccag aagttttgaa tgttacgaaa aagcagcagc gtatatcaaa gaaaatggtg
    33961 cgccaatcgt agtgaaagcg gacggcttag cagctgggaa aggtgtagtc gtggctacca
    34021 cagtgaagga agcgctggat gcggcagaac aaatgttgaa ccagcatcga tttggggata
    34081 gtagcaaaaa aatcgtcgta gaagagtttt tggcaggaga agaattctcc cttttggcgt
    34141 ttgtccgtaa taccaaggtg tatccgatgg tcatttcgca agatcataag cgggcatttg
    34201 ataacgataa agggccaaat acaggcggaa tgggtgctta ttcaccagta ccgcaaattt
    34261 caaaaaagat gattgaaaaa gctgtggaag aagttttaaa accagcggct ttgggaatga
    34321 aagaactagg acgctctttc acgggtgttt tatatgcggg tttgattgct acgaaggaag
    34381 gaccaaaagt gatcgaattc aatgcgcgtt tcggtgatcc tgaaacgcaa gtcgttcttt
    34441 ctcggttgaa gagtgacttt gcgcaagtaa tcgatgattt attagagaat cgtacagtag
    34501 agttaaagtg gcagcaagaa ggatacaatg taggcgttgt ggttgcagct gccggttacc
    34561 ccgaagaata tgagacagga atggttctac cagattttct ggaagaagag ctttctgttt
    34621 actatgctgg agtttcctca aataacggca aactagttgg agcaggagga cgtctttatt
    34681 tagtagaagc atacggtgag acgatcaaag aagcacagaa aaaaatttac accgcgttaa
    34741 tggataaaac gacagatgga acattttatc gtacagatat tggagaaaaa gctgccaata
    34801 gcgaactgat cgtgaagtaa atcagctgct tccatttata aaaaatacaa caaacataat
    34861 cggaagcgcc gattttagtg aagccttttc ataaagagtg tggtacactt ttgttgtgta
    34921 tataaataag gaggagttca gatgaaaaaa attcaattag gtacttctga tcagaaagca
    34981 gctgcagtga tcttaggctg tatgcgtatc aacaatgcgg aagatccagt aaaagtgatt
    35041 gagacagctt atgaaaacgg cattgatttt tttgaccatg cagatattta tggaaacggt
    35101 gaatgtgaag aaatctttgc agatgctcta gcaaaaacat caatcaaacg agaagatctt
    35161 tttattcaaa caaaatgtgg aatcgttcca ggtgtgatgt ttgatttttc taaaaaacat
    35221 atcattgaat ctgtagaaaa aagtttgacc cgtctgaaaa tggattatgt ggatgcttta
    35281 cttcttcatc gtccagatac attggtagaa ccagaggaag tagctgaagc gtttgatgaa
    35341 ttggaacggt caggaaaagt tcgttatttt ggcgtcagca atcaaaaacc aatgcaaatc
    35401 gaattgctga aaaaatatgt tcgtcaacca ttagtagcta atcagctgca atttggcttg
    35461 aaacatactg gaatgatcga tcaagggatt catgtcaata tgacagatga agcaagtatc
    35521 gatcatgacg gtagtgtact tgattattcc cgattgcatg atatgacgat ccaagcatgg
    35581 tcaccatacc agtatggatt ttttgaaggt gtatttatcg ggaacgaaaa attccctgaa
    35641 ttaaaccaaa cattagaaga actagcagct aaatatcaaa cgacaccaac tggcttggct
    35701 tctgcttgga ttttacgcca tccagccaat atgcaagtga tcgccggtac gatgaacgta
    35761 gggcgaatca aggaaatcgc tcaagcttca gaaattaata tgtctcggga agattggtac
    35821 gaattgtacc gtgctgctgg aaacatttta ccttaaagat tgtcataagc aggtcaaaag
    35881 ggctataaat taaaaagaca gaataacttg aaagctgttt tcagcttcga gatattctgt
    35941 ctttttttat tgcaaatgga aagagtatca ttgtacggat ttcgtttatt agttattttt
    36001 gtttttaagg aaaagctgtg tccgatattc ttttggagaa atcccttgtt ttttcttaaa
    36061 taaataactg aaatagttag ggtcattata accaatttca aaagcaatat ctgaaatacg
    36121 atagtctgat tgctgcaata atttttttgc taattcgatt ctttgttctg tcagataatc
    36181 gatgaatgtt tggttaaacg attgagaaaa aatcgtactg aaatgagagg gacttaatgc
    36241 aacttgttga gcgacccaag ttaaggacat atctggatcg gtaaaatttt ctttgataaa
    36301 atccaatgca tggttcaaaa ttggctgata tttgttcctt gaaggctgtg agggcagagc
    36361 agttaagaaa gaaatgaaca tataaactgt cgaacggtaa agcgagtcgt cggcgctgat
    36421 tgctaagcgt tgactggtgg atgtgcaatg aaccatttct tgcgggattt tcttttcttt
    36481 caggcagaca tgctggagta gcttagtcaa gacaaataaa cgatataatc gtgttcgagt
    36541 tggtgtgcct tgtggtttcg tcaagtgttc gatgtactta gatacttcgt ttttcgataa
    36601 tgaagacaaa tcaagtgaga ggtcaaagta aaagacagaa tcaactggaa gtttcgcttc
    36661 ttgaatcaaa tcctcatagc tgataatttg ttctttaagg gaactggcgg tttcaagtat
    36721 catctgcgtg atctcaaaag atgcaggtaa ttcgctgatt ctttctgcga caggaccaat
    36781 ggcgacagaa aaattatttt tttgtccctt ttctaattca tggaccaacg tttgggctac
    36841 ctgataactg gtctcgatca cattttcttc aagagaatca actattaaaa atttgatgaa
    36901 tcgagaggaa acagcagaga agatcacttg ttgattctcc ctaaataaaa acttcaaata
    36961 atcactgaga tgagcgtaat cttcaaagtc tgtactgact tggtttgctg ctaataatac
    37021 ggtcattttt ttccctgcta aagagcgatt gaaagattca gcaagtttca atgtttcact
    37081 gatcgtaagt gagcctttga acaaaccgtt caagaaatga ttttttttca attcgaaaac
    37141 aagatcagaa gaagtgtgcg tttctttttg ctgcaaatct aaagcagtta ctgctttttc
    37201 tattgcttgt ttcaattcgc tacttttaat cggtttaagc agataatcat ctgcctgtac
    37261 ctggattgct cctttcatat aatcgaaatc gtcgaatcca ctaataaata tgagacgagt
    37321 ccaaggaagt agtttccttg cttcttttga aaaagtcaac ccgtccatga aaggcatttg
    37381 gatatcagtc agaatgatgt cgggctgtaa gtcgataatt gaagacagtg ccatctcacc
    37441 atctccagct tcgccgacat aagtgattgg ataataagaa ccaaggacag ttatttgttc
    37501 ccgcaagtta ttgcgaatga ggtattcgtc ttcgatgata aaaactttat acatgtttgt
    37561 ttcctccaat tgttttggga gatagaggga tcatcagtgt gacagttgtt ccttctcggt
    37621 atttgctgtc aatcgtgata ggtttttgat catttccgta ataaagaagg agacgcttgt
    37681 ttacgttgta aagtccgtag ccgatactga aatctgaatc gatccctttg gctaactctt
    37741 tacgtatttc tgccagtttt tctgcaggga tgccaatccc gttgtctata actttgaatt
    37801 ggatcatctc atcaattttg catgtggtaa tacgaataaa tcctttgtga cggacgtact
    37861 tcgttccatg gtatacagca ttttcaatca atggctgcaa gatcattttt aaaatagaaa
    37921 caggaaaaag tgtttctggt atatcgatct tatagtcaag catatggccg tatcttattt
    37981 ttaagatgac tagataatca ttgatatggc taatttcttt ttcaagagga atccagtctt
    38041 gtcctttgct taaagacgta cgaaaaaagc cggaaagtgc atgggtcata gtcagagctt
    38101 cttcaaagca gtcttgttcg atcaaagaaa taatggcatc caaactgtta taaataaaat
    38161 ggggagtaat ctgagcttgc aatacacgaa cttcactttg tgctaaatgg tattgtttca
    38221 aagcgttctc ccgtaaagac tggtttagat cttccgccat tttattcatg ctagcggtaa
    38281 gtgtttgtaa ttccagtgtt tccggcaggg ttaaacgaaa gccaaggttc cctgaagaaa
    38341 gttgttctga catctcgatc agctgattga tcggttcttg gacctttctc tctaaaaagc
    38401 gacgattctt tttcgcatag aaaaaaatgg tactaagaac tccaagttcc actattgtta
    38461 atagaatgag cgagcggaca agtgtcgtat tttttttgct tgctaagtcg atctccacac
    38521 gaacaaaatc ttgtaagata tctgacagca gttgagtgac agaatctacc tgattgatga
    38581 tctcttcatt ggtatccata aaatcttttg ccaagatatt attgatcagc tcgttttgat
    38641 aatcttccag tgtatcgatc gtacgtagcg atacatctaa cgtactaatt tctttaagtg
    38701 tatttgtatt atttttgctc tctcgaatat cattcctaag ttcttctagg atattttcct
    38761 cattgaactc atctacggtt acttggccag aaatcaagtc ccacatactt tccaaaactt
    38821 tttgatcaac cttcaaagca attgcatctg ctttttggat atttgcgatc gtctgttgat
    38881 aaatcaaaag ctgttgcgaa tataacagta tgctcagtag caaagggata acagcaaata
    38941 gaagcatggc tttgtttgct tgggcaaaaa tctgttttat gcttaaattt tttgtcatga
    39001 tacttctcca gtcaataatt tctggttggg atgttagcta tattctgcag ggaaaagaca
    39061 gtctcggaaa taaaaatatc tttaggtaat gtttttcctg tttgaatatt tccaaaataa
    39121 cgagtaacgg tattggctac ataccagccg acatcaggtt tacactcgac tacacaattg
    39181 acgattcctg agcgtagctt ctcgatcata tcttcttgtc catcaatagt tacaatgatc
    39241 aaatcttctc caggtttgat tgatgtttct tttatcgcag ctaaagcacc gtgagtcatt
    39301 tcatcactat ggctgtataa tacatcgatt tcggataaat catttgtttc taaatatcgt
    39361 ttcatctggt cttttccttt catccgaata aaatcaccga caattcggtg aacaatagtc
    39421 atcggaggtt tatggtcgat ggttccatct ttttttaggg ttggtttacg attgattgat
    39481 tccaaaaatc cttcggagcg tagcttggtc ggtgtggagt tctctgaacc agcaagttct
    39541 aggattctga tttcctgttt ctttgaattt gtgaagtgat tgctgacaaa taaacccgcc
    39601 cgatttcctt ctgctttgaa actggggcca atgtgggtga cgaaaagctc gggatcattc
    39661 gtttgaatat gtctgtcgac aagtatgaca gggatccctg ctcgctttgc ttcttttaat
    39721 acagagtccc acccggattc ttgcaaagga gtaaaaatga tcatatccac tttataggca
    39781 atgaacgtcc gtatatcttg gatttgccgt tcctgattca tgtagccatt tcggtagaga
    39841 acttggtaat cttctttttc aagcgcagtg ataattgatt cagtatgctt tttccgccag
    39901 ctactctccg ttcctgattg cgaaaaacca acgactagtg ggtcaggtgc ttcctttgta
    39961 ttaggtgtac accccatcat ttggtaagcg attacaacaa gggctaaaaa aaataaaaca
    40021 cgtttcactt taaatcactc catctggatt tgttagtact atcttatcag ataaaaggga
    40081 aaatcaaagt caaaaggaat caatcgaaaa aaatccaaga aacttaaaaa aatccaagac
    40141 aaaaaaagta cacctaaaaa atttaaagta aatcccataa aaaaatcaat gttaacgctt
    40201 tctttattag ctatactcgg tgtatcaatt gaaatggggg ataaaaaatg aaaaacaaat
    40261 ttagaaagat tgttgggact atcgctattt tgaccgcaag cattctatta agtgcgtgtg
    40321 gcaattcagg atctgcagat gatagtacgg ggtatgtagg aatcgctatg ccgaccaaat
    40381 cagcagaaag atggatcgct gatgggaaca acatggtctc ggaattagaa aaactgggtt
    40441 ataaaacaga tcttcaatat ggagaagata aagtagaaaa tcaagtagca caaatagaaa
    40501 atatgattac aaaaggggta gatacacttg tgattgcttc tatcgatggt tcggctttaa
    40561 ctgatgtgtt agctaaagca aaagaagcag atatcaaggt gatcgcctat gatcgtttac
    40621 tgatgaattc agaaaatgtc gattattacg cgacttttga taattttgga gtaggtgtat
    40681 cgcaagcagc ttatattgaa gagcacttag gattgaaaga aggaaaagga ccattcacga
    40741 ttgaattatt tggtggctcg cctgacgaca acaacgcact aatcaattac aacggagtga
    40801 tgtctgtttt acaaccatat atggacaacg gtcagttggt cgtgccatct ggacagacga
    40861 gtttcagtca aatcgctacg cttcgctggg atggttctac ggcgcaagca aggatggata
    40921 atctgttaag cgcaaattat actgaccaaa cattggatgc tgttttgtcg ccatatgatc
    40981 caataagttt aggaatcatt tcgtcattaa aaggcgtggg gtatgggagt gaaagtaaac
    41041 ctttacctgt gattactgga caagatgcga cagttgctgg cgttaaatcg atcattgccg
    41101 gggaacaaac acaaacgatc tttaaagaca cacgtatctt agcaaaaaat acgattgaaa
    41161 tgatcaaagc aatcagtgat ggagaagagg ttccggtcaa tgatactgaa acttatgata
    41221 atggggtgaa aactgtccct acgtatttag caaatacagt atctgtcgat aaagataatt
    41281 atcaagcaga gctgatcgac accgattatt ataaagaatc cgatctgaaa aattaagagg
    41341 aaccaaacaa ggaactaaag agatctaagt cagagagagg ataagaatta tggcggattg
    41401 tattttaaaa atggcagata tcaccaaaaa attttctgga atccgagcgt tagattgcgt
    41461 gaatctgatg attgaacgtg gggaaatcca tgcattgtgc ggagaaaacg gagcgggaaa
    41521 atcaacattg atgaatgtct tgagcggctt gtatccatat ggctcctatg acggggaaat
    41581 cttttatgat ggaaagctgt gtcaatttaa agatttgaaa gatagtgaag aaaaaggcat
    41641 cgtcatcatt catcaagaat tagcactaag tccttatctt tcaataaaag agaatatttt
    41701 tctcggaaat gaacaagcag aaagaggcgt gattgattgg gaactgacag aaaagaaaac
    41761 atatgaactg ctgaataaag tcggtttgtc tatcgacccg aatcttctag tatcccagat
    41821 tggcgtaggg caacagcaac tagttgaaat agctaaagca ttatcaaaat ccgtccgtct
    41881 gttgattttg gatgagccta ccgctgcatt gaatgaagaa gaaagcgcga atttgctgag
    41941 attgatccga gagttgaaag agcaaggtgt aacctccatc attatttcac ataagctgaa
    42001 tgaaatcgtg gatatcgcag atcgaatcac cattttacgg gatggacaga cgattgagac
    42061 actagaaaat gaaatgatca gcgaagagca tattattcgc ggaatggtgg gcagagattt
    42121 agttgatcgt tatcctgaaa gaaaaccgga tattggagaa gtttatttta aagtagaaga
    42181 ctggacggtc tatcaccctc ttgatcacga gcgaatcata aacgaccaca tcaacttgca
    42241 tttgaaaaaa ggagagattg taggaatagc tggactgatg ggagcgggca gaactgaatt
    42301 cgctatgagt ctatttggac attcttatgg aagcaagata tccggacgta tattaaagga
    42361 aggggcagag atatcagtta agaccgttcc ttcagccatt gcaaacggac tcgcttatgt
    42421 ctcggaggac cgaaaatctt taggactgaa tctgctgatg gatattcggg aaaacgtgac
    42481 gctgagcagt ttggataaaa taagtcaaaa aggagtatta gataaagaaa aagaagtaac
    42541 tgaggcagaa aatttccgga aaaagatgcg tataaaaaca aactccatcc atcaaattgt
    42601 cagtagtctt agtggtggga atcaacaaaa agtcgtttta tccaagtggc tgatgacaca
    42661 acccgatatt ctttttttgg atgagccaac ccgtgggata gatgttgggg caaaatatga
    42721 gatctacacg attatcgaag aaatggcagc aaatggcaaa gctgtctgtc ttatctcttc
    42781 tgaacttcct gaaatattag ggatgtgtga tcgaatctat acgatgaacg aaggacgtat
    42841 tacaggagaa gtctcgcgag aagatgcaga tcaggaagtc ttgatgaaat taatgacgaa
    42901 agaagaggtg ggttaagttg gaacaggcaa aaaatcttac ggataaaaaa gagaaaaaac
    42961 taaatttgaa aagtagagca gctgatcttt ttggtcgcta cagcatggtg atcattttag
    43021 cgggactact tattgcgttt caattgatga cggatggtat tttctggcgt ccattgaata
    43081 taactaacct tgttctgcaa aatagccata tattagtact agctgcaggg atgttattag
    43141 ttgtgctctt aggtcatgtg gatttgtcgg tagggtcagt gatggcgttt gttggtgcaa
    43201 ttgcgggcat gatgatggtc aatcgccaaa tgaacccgtg gatgacagtt atcgcatgtc
    43261 ttgcagtagg cgggctgatc ggcgcatggc aaggtttttg ggtagcttat gcagggatac
    43321 cggcgtttat cgtgacttta gcaggattgc tgatgtttcg tggactgaca caagttgttc
    43381 taggaggcca atctctagca ccttttccag ctgttttcca aaaaatgtct acgggttatt
    43441 taccagactt aagcgaagga agcagccttc acttcttgac attgatttta ggaatgatca
    43501 tcacgatcgt gttagttgtt ggtcaatggc gaacaagaaa tcgtcggaaa aatcatttat
    43561 ttgaagtgga atctccaaca gctttcttgg taaaggcggt atttacagca gtcgttgtac
    43621 taggaataac ttatatcttt gcctcttatc aagggtatcc gattattttg atcattcttg
    43681 gtttgatcgt tgcagcatat gggtttttga caaataaaac agtagcaggt cgacagattt
    43741 atgcgacggg cggaaatcga aaagcggctg aactatcagg gatcaaaaca aagcgaatca
    43801 cgttctgggt attcgtcaac atgggagtca tggcagcttt agctggatta gttttagctg
    43861 ctcgattgaa tgcggcaaca cctcaagcag gtacatcgat ggaactggat gcaatggcgg
    43921 cagtatattt tggtggtgct tcgacttccg gcggcattgg aacaatcatg ggtgcgattg
    43981 tcggtggctt ggtcatgggt gtattgaaca atggcatgtc gattttaggc gtcggggtag
    44041 actggcagca ggcaatcaaa ggattgatct tgcttttagc cgttgtgcta gacttgtata
    44101 ataagaaaaa acgaacaacg taggagaacg ccggttattc agaaaaaaga ctgtgacaag
    44161 acatttgtca cagtcttttt ttcgctaaaa gcgaacattc attgtttcgt ttgtatagac
    44221 taaaaataat atatgttttt ttaccattcg tataaattct ctttttgctc ttgatttttt
    44281 tgcttaattg agttaaatta catagggcgc taaaaaaagc cttgattaaa ttaataatgt
    44341 tcgtgttttg ctggatgtga acatcaggag gataatgtaa tgaaagtatt tgattacgaa
    44401 gatattcaat taattcctaa taaatgtatc gtaaatagcc gttctgaatg tgatacaacg
    44461 gtcacattag gtaaacatac attcaaaatg ccagtagtgc ctgccaacat gcagacgatt
    44521 attgatgaaa caatcgcaga attcttagcg gaaaatggtt atttctatat catgcatcgg
    44581 tttgatgaag cagctcgaat tccgtttatc aaaaaaatga aaaagcgtgg attgattacc
    44641 tcgatcagtg ttggcgtcaa gaaagaggaa tattccttta tagagaagtt ggcagaagaa
    44701 tcgctaaatc ctgattatat cactatcgac atcgcgcatg gacatgctaa ctcagttatt
    44761 gatatgattc agcatattaa aaaatatttg cctgaaactt ttgtgattgc cggtaatgtt
    44821 ggtacaccgg aagccgtccg tgaattggaa aatgcgggcg cagatgcaac aaaagtcggg
    44881 attggtccag gaaaagtatg tattacaaaa atcaagacag gctttgggac tggaggctgg
    44941 caactggcag ctcttagatg gtgtgcgaaa gcagctcgca agccgatcat cgctgacggt
    45001 gggatcagaa cacatggcga tattgcaaaa tctgtccgtt ttggtgcgac aatggtcatg
    45061 attggttcat tgtttgccgg tcacgaggaa tctcctggcg aaacaaaagt cgaaaatgga
    45121 atcgtgtata aagaatactt tggttctgct tcagaattcc aaaaaggcga aaaacgaaat
    45181 gttgaaggaa agaaaatctg gatccaacac aaaggatctt tgaaagatac actagtggaa
    45241 atgcaacaag accttcaatc atctatttct tatgctggag gaagagatct ggaagccatt
    45301 cgaaaagttg actatgtcat cgtgaaaaat tcgattttta atggagacac aatctaaaaa
    45361 ataaataaaa tattaggatg ttgtgaaaaa gttgtcctgc attaagtaat aagaacagcc
    45421 aaacaaaaat agttctttat atgttttgtt tggctggaat tattatcgca gatacaagct
    45481 tttgaacatc attattcaga ataagggact gtgataagat ttttgtcaca gtcccttatg
    45541 ttttgcaaaa aaagtttttc ttttttctcg taaattcggt aaaatcaaaa gaaaaaatag
    45601 acaatagaaa agagaagctt atgtgggaaa aagtagagaa aaaacaagga ccgatttatc
    45661 gtcaaattat ggaacagatt atgagagaaa tcgaaaacgg aaggatcaat cctggaagtc
    45721 aacttgaatc agaacgaaaa ctagggcaac tttttggtgt gaatcgttcc accgttgtcc
    45781 atgcattgga agagcttagg gagcttgggg tactaacgag caaacgtggc agcggatggt
    45841 ttgttaatca gactgaatgg gggaaattcg ctgttccaag aatcgattgg cggcaaatga
    45901 tctctcctcg ttatgagcag acggactggt atgagcaaaa aataagagaa gcaaagcaga
    45961 tccaaaaaac atcgtttctt gatttatacg ctagcgagat gccagatgag cttttgccga
    46021 attttgagtt tccttcttat tctcttgaag aaatcttagc ggaagaaaaa gaaatggatc
    46081 ttttaggcta tactccgtta cgtaacaaaa tcaaacggta tttggaaagt aaatttgaat
    46141 tggcattttc ccccaaccag cttcttgtga ctggtggcgg tcagcaagca atctttttga
    46201 ttttacaaac gattctttca gctggagagg ggatagctgt agagtcacct tctttttttt
    46261 accgattacc tcttttcaaa gcttcaggaa cgcgtttatt tgggataccg atggatgaag
    46321 aagggatcga cttagaaaaa ctgaaagaat cgatccataa aaataaattg aaagcagtgc
    46381 ttatcaaccc gaattttcaa aaccctacag gaaaagtgat gagtcaaaaa cgacgagaaa
    46441 agctagtaga attgtgtcga cagtatcggc ttccaattat tgaagacgat gtatttacgg
    46501 atctttcatt tctaaaccaa gaagaagtcc ttcctatacg aacgattgat ccggataatg
    46561 tgttatacgt cggttcgtta tctagggttt taggaaaaac aacgaaaatc ggttgggtga
    46621 taggacctga gacttttatc tcgcaactag ctcaagcgca agaaatgatg gagttttcga
    46681 tgaatatcct tacacaaatc acagtggcta atgtatttaa tgaagcaatt gatttgaaaa
    46741 tgcaagatgt aagaaaaaag ttgaaagaaa aaagccgact gataagcgct tggggagatt
    46801 cacaatcgtt tttcaagctt cattcaattt taggtggtta ctatgcctgg attacttggg
    46861 atgggaaaaa actagacccc gaactagcag aaaaagtagt agatatgggt cttggaattg
    46921 caccaagtct actttttggg caagatataa atggaatcag aatcaattac agtaggctgg
    46981 atgaaaacca aataccgttg ttttattcaa agatgaaaat tctagaaaag tggttaacag
    47041 aataatttca caaagtaaat agattaaaga atataacagc ttggatttaa atttcaagct
    47101 gtttcttttt tttcggaaaa agaatacgat ataaagaaac taagaaaaaa ccattatttg
    47161 tacgtccgtt cacgatgtgt aaataaaata aatgtttgca acaaaactgt ataacaccaa
    47221 cgtttttaaa tagaaacaga tggttgtaag tttgattaga aaatagaaaa aatgcagatg
    47281 aaatataaaa cgctttcctt attgtgattt tattcactaa tgctgttaat atgcggattg
    47341 gcataatttc ctttcatcgt gaaaatttgt gcttttagct tgtatttctc ataaatccat
    47401 gataatttat taatgaagac ggttaaatag tgatacagtt ttattcactg tttcaatcgc
    47461 agaatgaaga gattttctta tagatgagag aggaatgtgt gacaaatggc aaacaaaaaa
    47521 gcaccgatcg acttccaagc actgctagat gaagtcaatg cagatttccc agtatatcaa
    47581 gcacttgatc aagatggaaa cgtagttaac aaagatttag tacctgattt atccgatgat
    47641 gaactcgttg aattaatgac tcatatggta tggtctcgtg tattagacca acgttcaaca
    47701 gcgctgaacc gccaaggacg cctaggcttt tttgcaccaa ctgctggaca agaggcaagt
    47761 cagctggcta gtgcttacgc atttgataaa gaagatgttc ttcttccagg ttatcgggat
    47821 gtacctcaac tagtaaaaca tggtttacct ttatctcaag cttttttatg gtctcgagga
    47881 catgctgcag gtaattctta tccggaagaa ttgaaagctc taccaccaca aattatcatc
    47941 ggtgcacaat atgtacaagc agccggtgtt gcattaggtt tgaagaaacg aaacaagaaa
    48001 aatgtcgtct tcacttatac tggtgatggc ggttcatcac aaggtgattt ttacgaagca
    48061 atcaatttcg ctggcgctta ccatgcaaat gccgtatttt atatccaaaa caacgggtat
    48121 gcgatctcta cacctcgtga aaaacaaact gcagcaaaaa cacttgcaca aaaagctgtc
    48181 gcagctggga ttcctggtat tcaagtcgat ggaatggatc cgcttgcagt atatactgta
    48241 tctaaaatgg cacgggaatg ggcgatcagt ggaaatggac cagtcctaat cgaaacactg
    48301 acttatcgtt atggaccaca tacactatct ggtgacgatc caacccgcta ccgtacaaaa
    48361 gacacagatg acgattggca gaaaaaagat ccattgatcc gcttccgtaa atatttgacg
    48421 gaaaaaggac tttggtctga agaaaaagaa gaacaagtca tcgaagcaac taaagaagaa
    48481 atcaaagcag ctattgctga agccgacaaa gtaccaaaac aaaaggtttc agatttcttg
    48541 aaaaacatgt tcgaagtatc tccacaatca atcaaagaac aaattgcaat ttatgaagcg
    48601 aaggagtcga aataatcatg gcacaaaaaa caatgatcca agcaatcaca gatgccttag
    48661 cacttgaact agaaaatgac gagaatgtcg ttgtttttgg tgaagatgtt gggaaaaacg
    48721 gaggagtttt ccgggcaact gaaggattgc aggaaaagtt cggagaagac cgagtattcg
    48781 atactccttt agctgaatct ggaatcgcag gattgagttt cggtcttgcg ttagaaggat
    48841 ttcgtccagt tcctgaaatc caattctttg gttttatttt cgaagcaatg gacgaagtag
    48901 tagctcaaat ggctcgtaca agatatcgaa tgagcggcac tagaaatcta cccatcacaa
    48961 ttcgttcgcc atttggtggc ggtgttcata caccagaatt gcattcggat aatttagaag
    49021 gtttgatcgc tcagtctcct ggtattcgag tagtgattcc ttccaaccct tatgatgcaa
    49081 aaggactatt gatttcttct attagaagta acgatccggt tgttttccta gaacacatga
    49141 aactatatcg ctcattccga gaagaagtgc cggatgaagc ttacgaagtt cctttggata
    49201 aagcagcagt tactcgtgag ggaacagatg tatctattat cacatacgga gcaatggtgc
    49261 gtgaagcaat caaagcagca gacaatcttg caaaagaaaa tatatctgtt gaaatcattg
    49321 atcttcgtac agttgcgcca ttagatgtag aaacgatcat tcaatccgtg gaaaaaactg
    49381 gtcgcgtagt tgttgtccaa gaagcacaac gacaagcggg cgttgccgcg caagtagttt
    49441 ctgagatctc agaacgcgct atcctttcat tagaagcccc aatcggacga gtttctgcac
    49501 ctgatacagt cttcccattt ggacaagcag aaaatgtctg gttgccaaat gcaaaagata
    49561 tcgaagacaa agtaaaagaa atcgcggaat tttaagaaaa gaagggacga aacaaagtca
    49621 tggcttatca atttaaatt
//
LOCUS       DACGMI010000017        46121 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.017, whole genome shotgun sequence.
ACCESSION   DACGMI010000017 DACGMI010000000
VERSION     DACGMI010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46121
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.017"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            414..947
                     /locus_tag="IXT46_001085"
     CDS             414..947
                     /locus_tag="IXT46_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAQ4947012.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(1437..1961)
                     /locus_tag="IXT46_001086"
     CDS             complement(1437..1961)
                     /locus_tag="IXT46_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4947013.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(1954..2427)
                     /gene="tsaE"
                     /locus_tag="IXT46_001087"
     CDS             complement(1954..2427)
                     /gene="tsaE"
                     /locus_tag="IXT46_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAQ4947014.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(2550..3530)
                     /gene="pta"
                     /locus_tag="IXT46_001088"
     CDS             complement(2550..3530)
                     /gene="pta"
                     /locus_tag="IXT46_001088"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAQ4947015.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(3683..4363)
                     /locus_tag="IXT46_001089"
     CDS             complement(3683..4363)
                     /locus_tag="IXT46_001089"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAQ4947016.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            4489..5358
                     /locus_tag="IXT46_001090"
     CDS             4489..5358
                     /locus_tag="IXT46_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4947017.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            5384..5899
                     /locus_tag="IXT46_001091"
     CDS             5384..5899
                     /locus_tag="IXT46_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947018.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(5946..6509)
                     /locus_tag="IXT46_001092"
     CDS             complement(5946..6509)
                     /locus_tag="IXT46_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4947019.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(6564..6743)
                     /locus_tag="IXT46_001093"
     CDS             complement(6564..6743)
                     /locus_tag="IXT46_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947020.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(6820..7329)
                     /locus_tag="IXT46_001094"
     CDS             complement(6820..7329)
                     /locus_tag="IXT46_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947021.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(7425..7805)
                     /locus_tag="IXT46_001095"
     CDS             complement(7425..7805)
                     /locus_tag="IXT46_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAQ4947022.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            8135..8884
                     /locus_tag="IXT46_001096"
     CDS             8135..8884
                     /locus_tag="IXT46_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAQ4947023.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(9068..10345)
                     /locus_tag="IXT46_001097"
     CDS             complement(9068..10345)
                     /locus_tag="IXT46_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947024.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(10424..11068)
                     /gene="pcp"
                     /locus_tag="IXT46_001098"
     CDS             complement(10424..11068)
                     /gene="pcp"
                     /locus_tag="IXT46_001098"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAQ4947025.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(11267..12211)
                     /locus_tag="IXT46_001099"
     CDS             complement(11267..12211)
                     /locus_tag="IXT46_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAQ4947026.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(12213..12899)
                     /locus_tag="IXT46_001100"
     CDS             complement(12213..12899)
                     /locus_tag="IXT46_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAQ4947027.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            13372..13692
                     /locus_tag="IXT46_001101"
     CDS             13372..13692
                     /locus_tag="IXT46_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAQ4947028.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGLLLISIIGIKI
                     TSGH"
     gene            13853..14758
                     /locus_tag="IXT46_001102"
     CDS             13853..14758
                     /locus_tag="IXT46_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4947029.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSEGTIRIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVKQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDQAARTILTDAGYPLEDPDKIKLLKKNEELLGTVIQLLSAENVHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            14755..15528
                     /locus_tag="IXT46_001103"
     CDS             14755..15528
                     /locus_tag="IXT46_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4947030.1"
                     /translation="MTLLIKQELFKLIKKKSTAVLSVLLVALLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMESQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSIYLYLLAIIVTVLMKLILFPSISFTEKISTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIALFLALGYLVFKRKNV"
     gene            complement(15705..17129)
                     /locus_tag="IXT46_001104"
     CDS             complement(15705..17129)
                     /locus_tag="IXT46_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4947031.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGFLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            17340..17786
                     /gene="nrdI"
                     /locus_tag="IXT46_001105"
     CDS             17340..17786
                     /gene="nrdI"
                     /locus_tag="IXT46_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAQ4947032.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            complement(17856..19838)
                     /locus_tag="IXT46_001106"
     CDS             complement(17856..19838)
                     /locus_tag="IXT46_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4947033.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(19852..20748)
                     /gene="murQ"
                     /locus_tag="IXT46_001107"
     CDS             complement(19852..20748)
                     /gene="murQ"
                     /locus_tag="IXT46_001107"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAQ4947034.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            complement(20751..21812)
                     /locus_tag="IXT46_001108"
     CDS             complement(20751..21812)
                     /locus_tag="IXT46_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAQ4947035.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(22024..22551)
                     /locus_tag="IXT46_001109"
     CDS             complement(22024..22551)
                     /locus_tag="IXT46_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4947036.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQALAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELISYE"
     gene            complement(22618..24120)
                     /gene="lsa"
                     /locus_tag="IXT46_001110"
     CDS             complement(22618..24120)
                     /gene="lsa"
                     /locus_tag="IXT46_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lsa family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAQ4947037.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            complement(24378..25499)
                     /locus_tag="IXT46_001111"
     CDS             complement(24378..25499)
                     /locus_tag="IXT46_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAQ4947038.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            25625..26566
                     /locus_tag="IXT46_001112"
     CDS             25625..26566
                     /locus_tag="IXT46_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAQ4947039.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(26709..27605)
                     /locus_tag="IXT46_001113"
     CDS             complement(26709..27605)
                     /locus_tag="IXT46_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAQ4947040.1"
                     /translation="MNKNDVLLIAKNKSLYFFPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAEKYKQEFTKR
                     GVTTNYFILPLRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYQFYHSENIFLLQERDLDELPEFLHTPFQPIPSELLEFFDAENWAKR
                     FFTTDSAIYEQYEYDLSSVKNK"
     gene            27887..29227
                     /locus_tag="IXT46_001114"
     CDS             27887..29227
                     /locus_tag="IXT46_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4947041.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGIILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHAADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFAAYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLIIFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLTLRKGTLW
                     DKGISFFALAVLWLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            29422..29865
                     /locus_tag="IXT46_001115"
     CDS             29422..29865
                     /locus_tag="IXT46_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAQ4947042.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINAMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(30127..31545)
                     /gene="nhaC"
                     /locus_tag="IXT46_001116"
     CDS             complement(30127..31545)
                     /gene="nhaC"
                     /locus_tag="IXT46_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAQ4947043.1"
                     /translation="MEKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKKYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDILEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPKLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(31949..33172)
                     /locus_tag="IXT46_001117"
     CDS             complement(31949..33172)
                     /locus_tag="IXT46_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAQ4947044.1"
                     /translation="MTTTLSTNQLKDLIQYRLPEYQALALAIHDHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTGFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDEIGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDAALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAALSTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSEKGLASIAIAAELLANTALDLLREPKLLEKIKQE
                     HQEIVARKKQEGATF"
     gene            complement(33204..34043)
                     /locus_tag="IXT46_001118"
     CDS             complement(33204..34043)
                     /locus_tag="IXT46_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAQ4947045.1"
                     /translation="MKKIIRFAVITFVAIIWLAGCSQGKAATTEKKETTVKLGIIGED
                     TDVWDDVKDRLKKENIHLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNEEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENKKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDEHARPYVNIIVARKEDEDNKTYQKIVDAYQTEETAKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(34060..34740)
                     /locus_tag="IXT46_001119"
     CDS             complement(34060..34740)
                     /locus_tag="IXT46_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4947046.1"
                     /translation="MTEFFKTYLPNVYLIPDEFIEATKQTLYMSFWTAFIGGIIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILVLVFLSQFISN
                     QLIKKVTH"
     gene            complement(34742..35815)
                     /locus_tag="IXT46_001120"
     CDS             complement(34742..35815)
                     /locus_tag="IXT46_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4947047.1"
                     /translation="MIELRDISVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEAGK
                     IIEKGSSIQIFSHPEEELTKDFIRTATHLDQALETISAHAAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKVTILQKNELDNRIKVIEGGN"
     gene            complement(36465..37136)
                     /locus_tag="IXT46_001121"
     CDS             complement(36465..37136)
                     /locus_tag="IXT46_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4947048.1"
                     /translation="MKGAIFDLDGLLVDTERTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KKWKQSFDILVQAAGSPEKVQEVRAKREEYFYQQLTSGAIQLKPYAKEILTDLKERHM
                     KLGIATTTVTKRATDILDHFQLADYFDTFTFGDEVSENKPSPVPYLTALERTGLEALS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYSVEEKEKLNLLAEGKDLRTVIEMLD
                     KKTEK"
     gene            complement(37224..39902)
                     /gene="mgtA"
                     /locus_tag="IXT46_001122"
     CDS             complement(37224..39902)
                     /gene="mgtA"
                     /locus_tag="IXT46_001122"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAQ4947049.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASPNGLS
                     EEQIERSRETYGENAISYGKKTPFIIEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGEYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNDTLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEAAETLDTDTINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVAPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELITGEKISEMNDHELAQVAEEHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGKFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKIPFIQSNATFAMLVITTLGIIVGSVLPFTGFGAELGLM
                     PLPGNYWLWFFITVVAYLALVTAVKKIYIRRFQELL"
     gene            40562..40999
                     /gene="ndk"
                     /locus_tag="IXT46_001123"
     CDS             40562..40999
                     /gene="ndk"
                     /locus_tag="IXT46_001123"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAQ4947050.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFATMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKGADAVPGTIR
                     GDYALPGTENIIHASDSRDAATKEIARFFPPFDTNKPSEKAAK"
     gene            complement(41021..41887)
                     /locus_tag="IXT46_001124"
     CDS             complement(41021..41887)
                     /locus_tag="IXT46_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4947051.1"
                     /translation="MYDGELIKKLRVNKKLTQTQLAEGICSKTSLVGIETNSVKKVSF
                     GTLKSFLERMNMTLAEYEWIRNQLDEPKKLKKKRRMLDRIQEDSFDPYKEIANNRRHY
                     KKTEDLYYLVLNLHMSKKTEVSETEFEFLRYECRIIEEYLMQVPEYGQFEVSILADFP
                     WIFSDRFIENNYLKIKKRMRRIAQLNNHEQYLFTFLTNLTLFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKSENHQEFFAVIEYTLGKNQGNSL
                     EKKLLAIAKPSS"
     gene            complement(42121..44199)
                     /locus_tag="IXT46_001125"
     CDS             complement(42121..44199)
                     /locus_tag="IXT46_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAQ4947052.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVSKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPATLGQTEGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTIL
                     YPVTGTNAEQ"
     gene            44692..45909
                     /locus_tag="IXT46_001126"
     CDS             44692..45909
                     /locus_tag="IXT46_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4947053.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETREKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEASPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
BASE COUNT        13388 a         9690 c         8175 g        14868 t
ORIGIN      
        1 cttattaccg cagatgcaag cttttgaaca ccgtttattg agaagttgtg aaatcagcgt
       61 cctgacctga gtattagaga aacaaatggc aaaatagttc ctcatatttt gctatttttt
      121 gagctaatac cgagggtcag ctgattgaac accgtttagt ggagaagttg tgaaaaagtc
      181 gcctactttc gagtcgtaag aaattttttt gaaaatggtt cctcacaact ttgcataaat
      241 ttgacttaat accgagaagt catgatcccc atctaactcc aaatcacaag gaatgagttc
      301 aaaaactagc ttttctcaac aaatattaca taaaaaattc tatgtttttt gttaaattta
      361 tttgcttttt tcaaaagtat gttacagtaa tttcccaagg aggttttaca gaaatgaatt
      421 ttgttgccat ggattttgaa actgccaatc atcagcctta tagtgcttgt tctcttgcgc
      481 tagtcatggt aaaaaatagc cagatcgttg atgaattcta tacattgata cagcctgaga
      541 ctcctttttt ctggcgaaat gtccaaattc acggaatcca tcaagaagac gtacgcaatg
      601 cgccgaaatt cccagaagtc tggcaaacta tccaaccata ttttcaaaaa aatcgtttag
      661 tcgttgcaca taatgctgct tttgatacaa aggtcttagc gggatgctta gattattatc
      721 atcttgaaca gcctaattat ctttctttat gtacagtgaa aagtagccgt cgcctgtttc
      781 ctgaatttcc aaatcatcga ttgaacactg tgtgcgaaaa tttgaacatc caattagatc
      841 atcaccatga tgcattggaa gatagtcgtg catgtgcgga aatcctgctt tatcaagaaa
      901 aaaaattcgg gacagatcca ttgaaaaaac ttgtgactat aaagtaaaag aatacttatg
      961 aaacacacaa agaggtcgtg agcctgccgt ttcactccga gtcacaagga gcaatttcaa
     1021 aaaatagctt ctcatgttta ttaaatattg tgactggtga ccgaggagct ggcaggagaa
     1081 caccgtttat tggagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
     1141 acaaaaatag cttctcatat ttttcatttg gttggactta ttaccgcaga tgcaagcttt
     1201 tggacaccgt ttaccaagag gttgtgaaat cagcgttttg acctgagtat tagagaaaca
     1261 aacggcaaaa tagttcctca tattttgccg ttttttgagc taataccgaa ggtcagctga
     1321 ttgaacaccg tttattcaaa aaaaatggac tgcgacacga cttttgtcac agtcccttcg
     1381 tgtgtttttc tgccttctca aaaggatgac agtttctcac tcttttccta tttcttctat
     1441 tcaatcaaat aactcatttt atatacatct aaaaattcac ctagatctgt tcttgcccct
     1501 ctaggcatga ccgcttcgat ttggaagccc atttttcggt aaaggtgtac ggctctttca
     1561 ttacgaactt gaacgtcaag ctccaatcga aaaagtacac ccatttcctt cgcccaactg
     1621 atgatttctt ctagcataag agtgcctagt cccattcccc aatattcctg cagaatactg
     1681 ataccgactt ctcccacgtg agacaaacga aattgactgt ctgccttgac agatgctgtt
     1741 ccaataatcg tcccttcata gattgcaagc agcaataaat tattattgct ttcgtatata
     1801 taatccaact cttcttctaa ggtttctggt ggtaacagga gttctgcttc atccaaaact
     1861 aaaaattctg tctccttatt aacttgtccc atcatcaaaa gaatgtcttt tgcatctcct
     1921 ggcactgctt cccgcaagat gatcccaact tcttcactca tgattttcag cccatttttc
     1981 tagaattcgc tgtttgaagg tttcactttg ctccccgtat gagattagtt tcacataccg
     2041 cttttctaaa tctgtatcac ttttttctaa aatcagttcc aaataatcct ccggcagtgc
     2101 ttcttctaat agatttcccc attcaacaac ggaaagccca tcaccttcaa aatattcatc
     2161 taaccctaaa tctgctccgc tagctgctac ccgataaata tccatatgat acaacggaat
     2221 ccgaccttga ctatattctc taataatcgt gtatgtcgga cttttgatca tttgcgttat
     2281 ccctaatcct tgggcaattc ctttcgtcaa cgttgtttta cccgcaccta gatcaccagt
     2341 caatatcaga ttgtcacctg gcattgcgga atgaccaatt gcctctgcga attgttctgt
     2401 cattgttaat cctgatagtt cgatcatttt tcatcttctc ccgctcttct ttctttttgc
     2461 cagtatatcg cgtaatgaag tttttttaaa gaaaaaatga actagtcaag aacagcagct
     2521 gctgtttttg gctagttcgc gtgtatttgt taatcaatca atgtttgtgc tgctgtgata
     2581 atcgataatt tatatacatc ttcttcattt gctccacgag acaaatcaga aaccggtttg
     2641 ttcaagcctt gtagaattgg tccgattgct tcaaagttac cgaaacgctg agcaatttta
     2701 tagccgatat ttcctgactg caattctgga aatacaaaga ctgttgcttg accagctact
     2761 tctgaatctg gcgctttcag ttgtgcaact gaaggaacat aagaagcatc aaattgcaat
     2821 tcgccgtcga tcatgtattg tggcgctagt tttttagcga ttttagttgc ttcaactact
     2881 ttgtctactt ctggcgattt cgctgagcct tttgtcgaga agctcatcat tgctactttt
     2941 ggttcgatat cgaacaattc tgctgttttt gcagaatcta cggcgatttc agccaattct
     3001 tgcgcagttg gattcacgtt gatcgcacaa tccgaaaaga catatttttc ttgatctctt
     3061 ccacgtacca tgatcatcgc tccgcttgtc cgactgatgc caggctttgt tttgatgatc
     3121 tgaagtgctg ggcgaacagt gtcgccagtc gaatggatcg ctccagagac cattccgtct
     3181 gcaatcccca tatacgtaag catcgtacca aagtaattca catcttttaa aatcttttct
     3241 gcttgttctt tggatgcctt tccatttcta cgttcaacaa aagtatccac catttcatcc
     3301 cacttatcgt aattatcagg gctgatgatc gtaaagctag atgttttgat tcctctggca
     3361 tgcgctgcat ttcttatttc ttcttcgttc cctactaaaa tgggttccac aagttcttct
     3421 gctttcaacc gggcagctgc gcctaaaata cgagcatcag tagcttccgg gaaaacgatt
     3481 ttgatcccac ggcgaacaat tttaaatctt aaactatcaa acaattccac aagatgacct
     3541 ccagacgttt ttatatgtat tatcatacac tattccagaa aaaaagaaca gtttatttta
     3601 tctgtatcag tcaaaaatgc tggaaaaatt aagtttttca catacaaagc gaactgcact
     3661 ataacaggaa agcgctgttt tattacactg tttcaggcag ttgccaatca atcggttctt
     3721 ctcctaacgc aaggagcgca tcattcgttt tcgagaaggg tttggaacca aaaaagccac
     3781 gacttgcaga taacggactg ggatgtggag atgttatgat gatatggcga ctcttatcga
     3841 tcattttgat tttttcttgt gccggttttc cccacaagat aaacacgatt ggtttttccc
     3901 gttcatttaa tttttcaatg atcgtgtctg ttaatctttc ccaacctttc ccgcgatgag
     3961 aatacgcttg cccttcccga acggtaagaa cggtgttgag taaaaggact ccctgtttag
     4021 cccatgacac tagatttcca tgttgaacag gtgcgattcc aagatcatca taaagctctt
     4081 tatagatatt tcttaacgat ggcgggatct ttacgccagg ttgcacagaa aaagataagc
     4141 catgagcttg attttctcca tgataaggat cttgtcctaa aatcaccact ttaacttctt
     4201 cataaggagt caattccaat gcttcataga tatgatacat atctggatgg atcttttggg
     4261 acgcatattc tttttttaaa aattctctta gatgcagata ataatctttt gaaaattctg
     4321 aggacaaaac ttcttgccaa ctgttatgaa tgatttcttt caaaaactcc acctcctaat
     4381 aaaaagaata actcacattt tcttcaatca caagggacaa tcttcaccct cagcacttga
     4441 ttaatatggt aaactaggaa caagaagcag aaaggaacga taatcattat gatcaaatta
     4501 attgcatcag atatggacgg cacattatta gatgcccata tgagtgtttc tcctgaaaat
     4561 gccgaggcga tacgttttgc aaatgatgcc ggtgttgagt tcatggtcgc tactggtcga
     4621 aactatcaag aagctcgcgc agctttagat gaggtaggaa tcgattgtgc gatgatcact
     4681 ttgaacgggg cacaggtatt tgataaagaa ggaaattcat tgtttaccgt gtcgattcca
     4741 aataatcaag caatctctgt tttagatatt ctagatgcta acggtattta ctatgaagta
     4801 gcaaccaacg atggtcttta ttctgaaaat caagcgaaac gaattgaaag ttttgcttcc
     4861 atggtggcta cccatttacc tcaccttacg tataaaatgg cgattgccat ggcctcagct
     4921 aagctggagt tattgcacat cacatacgtg gacagtattc gtgctatttt ggaagaaaag
     4981 aatctggaag ttttaaaaat tatttgtttt catacagaag ggccagctgt attaggtcca
     5041 gttggaaagc agatttctct tttaggcgat ctagccgtta cttcctctgg tcaaaacaat
     5101 atcgaagtga accataaaaa cgctcaaaaa ggaattgctg ttgcccatgt cgctcacgag
     5161 cgtgggattt ctttagaaga agtcatgacg attggcgata acttcaatga tgtcagcatg
     5221 ctgcaagtag caggagtcag tttcgcaatg ggaaatgcag aaatcgaagt aaaagattat
     5281 gccaaatata caacggacac aaaccttgaa tctggcgtag gaaaagccat attgcgcgcg
     5341 attgcagaag acttgtagtt ttatctagaa aagagggata tagatgtcag aatttttcat
     5401 tcaggaaaag cagcttggac gtgcaactcg gacaattgtc aaaaacgaaa aaggacattc
     5461 cctgtttttg atggttggtc gctggggaac aaagggcgat gcattgtctc tttatgccat
     5521 gaatggcgat ctcgttgctc acatcaagca gataagcctg acattcggta cgcgttttga
     5581 gctgtataaa gagttcgaaa aggtgggaac catgcagaaa atattcaatt ggcccggtga
     5641 cttttattat attcgtagac ttcactggac agtccaaggt gatatctata atcatcaata
     5701 tcaaatccat catttcaatc agcaaatcat gaaaatggat aaagcaacac ttttttcagg
     5761 agattactat gtattggatg tctcaaatga tgaagatgct ccagtttgta tttgtattgc
     5821 tgcggtttta gattactggc tctaccgtaa agacaaaagt cgcgataagc ctgtttctta
     5881 ccgacttaac ttaagttaaa aagatgtacc tgaaatgcgg aaatacgcat ttcaggtaca
     5941 tctttttaga tattcttttg catatgatca taaagatgac cactgatcat ccgctgaccg
     6001 acaactttga agtcatggcg ttcgtataat tttttagcct ttggattttt ttcatccaca
     6061 cttagaccga tgacggagcg attagctttc ttcgccaatt taggtaatgc ttctaataat
     6121 cgcgaaccga tgccttgtcc tctaaaatct tctgatacac tgatagagtc caaataccat
     6181 tcgttgggaa acgtttcttt atcaatgaac aaacgtgtag acgcatctag ctgatatttc
     6241 tctaagatag gtaccagtgg ctgatcgatg attgattctt cttcatctgt ataaccgtaa
     6301 gcaactcctg caactttacc gtctatttct tctacgatac ctcgtgaata actgtaacga
     6361 taatttggat cagtgattgc ttcttctaaa atctctaaag tcttttgttc ccctgtctgc
     6421 ttcaaaaatg gcagttccat atcttttaga atcactaaga tcaatggggc gatttctgga
     6481 gcatcttctt ttctcgcaaa acgaatcata gtttcctctc cttttctcca ttctaacatg
     6541 cagaaaaaga aatcgcaaaa tcgttatttt aaaaaatctt caatcttttc agtaatgaaa
     6601 taaccatgag taacgattct tgccgcttca gttcggcaat aagggcagac gactggcatt
     6661 tctttatcat tatgttcgac tacattattg acttcttcgt atgcaaattt ttttccgcaa
     6721 ttagggcatt tcattttttc catgttatct caacttcctt tcatctttac tctcttagct
     6781 tactcttata ttgtaaaaaa gagaagcaat atccttcttc tatgcagata tccatacctg
     6841 acggtcctgt tctccatcta ttaatcggac tttataataa ggacgttcat ctttgactag
     6901 aagtgtccac tctttcactt ttgctttttt cccgtagtag ctgactgctt ccttcatcgc
     6961 tgcttgcggt tgtttgaact cttccgtttt ttctatatca aaaagatgtt ctgcggcctt
     7021 ttccgtgtca tttcgtacgg ttgttttccc agtggatgga ttgactgcta tgacttgtcc
     7081 ttcacaaaaa aactggtatt catatgttgc attcgtagga ttctccaaat ctttttcaac
     7141 tgcaaaatga atagcagata tgttatgttc ttttgtttcg ttttttacga ttgctgctgc
     7201 ttttttcaat gagatccgat attcctggtc actaatatca tccatgtgaa aagcggcatt
     7261 gagcagtccc gtcataccgg taatccctat tacgatgagg gcagcaacac caaacatcat
     7321 ttttttcatt cttcattctc ctgtttcttt tttttaaaga atatcaagaa atgaacgaat
     7381 gaaaaatcga atgaaacgaa aaaaaagtga caattttgtt atctttattc gtgcagttct
     7441 aatggcaatc cgtctggatc aaagaaaaac gtcatttttt ttcctgtaaa ggtatcttct
     7501 ctaatcggtt ctgattcgat ccctaaggac tgcaattctg caattgtttc ttcaatatcg
     7561 tctactttga aagcaagatg acgcaagcca caagcttctg gatagtttgg tcgttgtggc
     7621 gcattagcaa ttccaaaaat ctccaattca gcacttccta gtttcagatc taatttatag
     7681 tcatctcgtt ctttgcggta attttctctg attacttcaa atcctaattt attaacataa
     7741 aaatcacgtg atttctgata atctgaaaca atgatggcta tatgatggat cgttgtaagg
     7801 ttcatatgag cactcctatt cttcgtttaa gctcggatct atattaatct ccagttccat
     7861 tgtaaatgtg tcagattgaa aaaaatagct gtttttcctt tttataagaa aaaaggcaaa
     7921 aaaaacagaa agtaggtcct ccaagacact cttcctgttc ccaatataat aaatgaaagt
     7981 aagaaattat attttcaaga aaacaaacag aaaattatca taacacaaat tatttataat
     8041 tgaaagacta gttttttttc aagaaaagca tacaatagat tgtgttagta aatacagaac
     8101 acactacatt tagtgtctta aggagtcctc atacatgaag tcatattttc agtttttagc
     8161 tcatcagcta aaaggctggc cgcaacaaaa ttattatctt ttctttttca gtcttggctg
     8221 ccaggtcatg actcttgtca atagtcccat cacttggctg tccgttatta catttatcgg
     8281 taccacgctt ggtgtattgt gtattttatc catcaatgcg gcaaaatcag tcaacggtat
     8341 tttaggtatt ttgtctgcga tttgttttat tatcgttggg ttttcagcaa agaactattt
     8401 aagtatcggt gaacagattg cttatatgat cacattggat atccccgtat tgttaagtaa
     8461 agaatggaat cataatatgg cttcaaaaat ccgaaaattc actggaaaaa gctggtttat
     8521 cgcaatcatc agtactttcc ttgtctatct tgtttcagga ttcctgattg gtcgttatac
     8581 agatgatcct cggccgtggg tagatgccat tgctttttct attagcttga ctgctggtat
     8641 catcagtttc ttgcgttaca acaaccaata ttactggtgg ttagcttcag ggcttgctca
     8701 aatggtcctt tggtatattt catttacgca tggatctgca agtttggcga tgttcgtgaa
     8761 cagctctgtt tacttgctga atgatgtcct tgcatttacc gtttcacctt ggtataacca
     8821 aaaagaacgt gaacgtatgc aaaaaatgga agaagaatac tacaacgcac aacaacacgc
     8881 ataaaaaaac tgagcgtggg acaaaagtaa agaacacttt tgtctcacgc tctaaacacg
     8941 tataaacggc ggaatcagaa gcaactcctt cggaaataag ctgaaattca caaaaatttg
     9001 aaaagcaatt ttcgtgaatt tcttcttatt tcttggagtt aaacgcttct gtcccagcct
     9061 ctatttttta tagtaattcc ttcagatact ttcttgcctc atcattgaaa cgcagtgatt
     9121 cttctaactt ctgataatat tccaacgctt gtttctgagc ttcagtaaaa cgataatgtt
     9181 ttcctttcca tttgtcgatt gtctcttgca catttccaga ttggatatct ttcactacta
     9241 gttgccattt ttcttttgag actgtacggt ctttcttatc agcagattgt atagcttctc
     9301 gttctttacg caatactttt aaaaaaccat ttctgactat ccgaggaatg ctgtcgaaga
     9361 acccttctgt aaaaccatag cgacaatatt gcttccaaat aaatagatag atttttggtt
     9421 ggatgaatcg ttggtttttc gcaaaatatt ccatctgagc agtgacttct ggtgttcgtt
     9481 gacgttttgt ctttctcaac acggaaataa atgtttcaaa ataagcatta ggatgtactg
     9541 gcacttcttc atatacgatg gattgccaat ctttacgtaa aaatgcgcga tagttgatca
     9601 agaattcttc tacatccttt actaattctt ctgcaaagtc gtcaaatagt tcttttttta
     9661 tctgtcgctt ttttgactgc ccattgatgt gttcacttat tttcttgatt tcattttcca
     9721 atgcttgata atccgctatg taaatcggca tttctacttg gcgaaattct gcgagccgct
     9781 gagctaattt tatatccggt aaatatggct gtttcatccg acgattttgg tacaagacaa
     9841 aacagtattt ttgccatagt ccttcaggaa aatcgatatt cttctgctta agccataata
     9901 attcgtctaa ggccagatca acttttgtca ttccctgatg gatcgaagct gccactgtcg
     9961 gagagacatg caggtgatcg gcaaagtggt tgatgcctag ttttaggatc tttccggttt
    10021 ttggcgattt aacgatgtat tgcactttta attctctacc acactcacaa tacaattttt
    10081 gctggcttcg ttttgttcga aaaaacggat tgatcttgaa gtcagaaaac acccaatctg
    10141 ttgcagctaa ataatgttct tccataaaac gagagctgat tagatatcgg cggtgcttat
    10201 cgactagttc ccgctgtttt ttcgttaatt ttgcatagat ctcccaacgt tgactgcttg
    10261 tgtattgttt agaaattttg atgggatagc ttttgctgat ttcttttgga aaccattctt
    10321 caaagacgga ttgccattct tccacggctg tttctttcct ttctaattac aaaaagctgg
    10381 ctactaacat aacgttagca accagccagt gtttcttgct aaattagtga gttgttccgg
    10441 catttccgga aatatcttct ttattttcta ctgctgcttc aactgcataa gtcaaagaag
    10501 aagcaatgtc ttctaaagac atagaaggcg tacccactgg acgatcgatc acttgatcgg
    10561 gtgagaatgg cacgtggatg aacccacctc gaattgccgg gaattgtgtt tcgatcaaat
    10621 gaagcaaacg atacatgata tcattgcaga caaatgttcc tgctgtataa gagatgtacg
    10681 ctggtagacc atgatcttgt acattttttg tcattgcttt gattggcaat gaggtaaagt
    10741 aagcggctgg accgttttct tctaaagccg tatcgaatgg ctgatttcct tcattatcag
    10801 ggattcttgc ttctgctaga ttgattgcga cacgttcgaa cgagactgct gaccgcccac
    10861 ctgcttgtcc gacacagatc acgacatctg gttggtgctg ttggatggct tctttgacta
    10921 cttgactgct tttttcgaat acggtcggta cttccacttt gatgatttca gcaccgctga
    10981 tttcatctgg catttttttt actgcttcat aggctggatt cactttgtcc ccaccaaatg
    11041 gatcaaaacc tgttactagt actttcatct gttgttcctc cgtccgattg atttaacata
    11101 tggttatctt ttatcatacc attttccttg aacagcgtaa ataaaggaaa caatagttta
    11161 aataacataa cagatcaaac ttaatatatt cttataaaaa aatagtgttc cactacaatg
    11221 ttagaagagg ttgcgacaat tattctgtca caacccctct cttctattat ttaaatagaa
    11281 tcatataagc aatttggaaa actagcataa ataacgcaat aaacaactgg tttttgatca
    11341 ctccgtattt gtctttcatc tccagcatcg ctacaggcac gatattgaag ttagcagcca
    11401 tcggtgtcag cagggtccca caaaaaccgc aagtcaatgc aaccattcct attaacgctg
    11461 gattcgctcc atgactaaat acgaatggtg caccgatccc aaccgtcatc acggtgatgg
    11521 ccgcaaatgc attccccatg attaccgtaa atatcaccat gccaagagcg taaatgatga
    11581 tgccgatgtt cacatttcct tctggaacga tcgtacctac tgcattggaa atcactgtcc
    11641 caactccagc gcttgtaaat accgcaccta gagaagctaa aagcattggc aacatgctta
    11701 acggccctac tgtgcccagc atatctgctg catcatctaa aaatgtactt ggtcgattat
    11761 ctcgagaaaa gaacatcaag attagcatgg ctgcaaaaac accgacgccc acgccgacta
    11821 aagcacctaa attggtaaat agagcaaaca agatcgcaaa gacaccgata ctcaaagctg
    11881 gaataaaaat tttcattcct agtttgtctg acattttttc catatattct tttgatggaa
    11941 gccggctttc tcctttgctg actttcttag caattgctgg tatggtcatc gcaaagatca
    12001 agccaccgtt cacgattgcc ggaagccatc ttcctcctgc aataactacc cctaagaccg
    12061 tccagaaaaa ggctgaccca taacgatgag gattggtttt atctgttaaa tttcttactc
    12121 cagtgtaaat caatacgagt cccatcacga tataaaggat ctccagtaat ttatcgccta
    12181 ataaaatatc aggatttgta aaaaagtcca tcttattgcc cctttcctgg ataatatttc
    12241 ttcgctaatt tcttttcttt aagatagaag tagacacttg ccacaactaa agccgtgata
    12301 gccactggaa cttccactaa agcaagctgt cccaatgtta cgtcatatcc tagatctttc
    12361 agtgttgatt ggactagcaa cgcccctgct cctccgatga atagtacttg gccaaagaac
    12421 cagcagacat tttccatagc tgaagccata ccttttagtt cttcttcatg cttaggatgg
    12481 acttctaacc cttttgattc gatggtcccc aatgccatcg gtaaaatgat tggacgaaca
    12541 aatccagcaa ctccaccaaa actcacgtta aaagccgcaa agatcattcg aaagatccca
    12601 taaatatcta caatcatacc agcagatact ttcttgaatc gcttgatcaa ggaagccgct
    12661 gattctttca gaccatttct ttcaagcgtt cctgttgcca acataatgat gataaaaatc
    12721 gccatcccgc gattgtttac aaaacttgta cctaaaagtt ctaacattcc ttgaatgcca
    12781 agaccgccag tcaaagctgt aacaactaaa gcaaccatta cgatcaatat cgagtctaat
    12841 ttaaatgcaa acccgagaat aacaatcaag acgcctaaaa ggctaagata attttccata
    12901 tattttcctc cataaaatga caatattttt ttaattataa agcaaaacac ataaaaaata
    12961 tagttgtttt ctcacgaaat agacactatt tttaaatatt tttcgttatt tttttattat
    13021 ataattcacc ttacttattg taagataaag ctttttttaa tttattgcct gctaatatat
    13081 aaaaataagg tctagttact gtttttttaa atgattaata aataacaact cctttctatg
    13141 aaattgcaaa gcattcatct tcttttctgc taacgatata tccgtcaatg cttgttacac
    13201 tttactaaaa agtatgagat tgccgatatc tggataggtg tgctatacta cagaaaaaga
    13261 tatacgatct gccaccgggt agtaaaaaag aggatgatca ttccattagg tctttgaagg
    13321 gatgattctc ctctttttgt gtatttttta tattgaagga ggaacgtatg tatggcatgg
    13381 atggaattaa tcatagcagg aattttggaa gtattctggt caacgatgat gaaatggagt
    13441 gatggttttt ctaaaatcaa ttattctttt tacacagtga ttggaatgat tgctagtttt
    13501 tactttttgt caaaggcaat caaaagtttg cctatgagtc tctcttatcc tatttggaca
    13561 gggattggcg cagttggttc ggtcattatt ggtgtggtct tgtttcatga taagctgaat
    13621 ctttccactt ggttctttgt cgggttgctg ctcatcagca tcattggcat caaaatcact
    13681 agcggtcact agatacttag acaagcagac aaggactgat cagaaaaagc ggggcttttt
    13741 atttgatatt cctctttcta tgaaaaaaca agaaaataag actaatgacc tagcgacttc
    13801 tctactcatc aggtgtatgc ttgtactatc tatagaaaag gagtgaatat ttttgaaaag
    13861 tctttcggtc caagaattat ccaagaactt tggtcacaaa caagccctca gcgatgtcag
    13921 ttttagctta tctcctggca aaatcgttgg attagtaggt cctaatggcg ctggaaaaac
    13981 aacgatcatg aaagctattt taggactgat ccattactca gaaggaacga tccgtattgg
    14041 tgaaaatgag atttctccct ctagtcataa aggattagaa caagtaggag cattgatcga
    14101 atatccgggt atctatccat tcttaacagg ttatgatcat ctgaagttat tctctgaaac
    14161 aaacgatgta tctgctatcg acactatcgt gaaacagctc aagatggaaa aatacattca
    14221 caaaaaagcg aaatcctact cgctgggaat gaaacaaaaa ttgggaattg ctcttgcctt
    14281 actgaaccat ccgtctatcg ttattttaga tgagccgatg aacggtttgg atccacaagc
    14341 aacaagagat gtgcgaaaaa tcattaccga cttggctact cagggcacct ctttcttgat
    14401 ctccagtcac ttactcagcg agcttgaaaa aatggtcgat gagctgatcc tgatcaatca
    14461 aggaaaaatc atcaaacaat gtacaatggc tgaattgaac caaacagcgc aagatttcat
    14521 cgttatctct acgacaaatg atcaagctgc tcgaacgatc ttgacagacg ctggatatcc
    14581 cttggaagat cctgataaaa tcaagcttct aaaaaaaaac gaagagttat taggaactgt
    14641 tatccagtta ttgtctgcag aaaatgtcca tgtgacagat gtccagcatc tgacgaatga
    14701 tttggaatct tccctattgg aaattctgga ttcagtaaag ggggaagaag aaaaatgacg
    14761 ttgcttataa aacaagaatt atttaaattg atcaagaaaa agtcaactgc tgttttatct
    14821 gttctattag ttgctttgct cataggaaca gcacttctag ccaaaaaata cacgacgatc
    14881 attgatccag ttgaaatgac tgctcagctt ttcagtgcca catcttggat tgtctttatc
    14941 atgattgctg ctgcaagtac gatcatttca atggaatcac aatatggtac attgaaaaat
    15001 ctcctttatc gaaagtattc tcgaggagaa atattagtaa gtaaatggat cacattagtt
    15061 atttattcta tttatttata ccttttagct attattgtca ccgtgctgat gaaactgatc
    15121 cttttccctt cgatttcctt tacggagaag atttctactg gtcagacact gatccaaagc
    15181 ttattcactt atactttggg tagttatatc ggtttatggc taattttaag tttagtgttg
    15241 atgattgctt gttttatcaa tagttccggt gcctccatct cagcagggat cgtcttttat
    15301 tttgcttcat caatcatatc tggtatcctc atcgcactca ttcaaaaatg ggagtggatc
    15361 aaatggaatc caatcagtat gctgaatctg caaaaccaaa ttggcaacga agagattatg
    15421 aagcaattga ctcatctttc tactaatcaa atgctgtttg gcaatttagc ttacattgct
    15481 ttgttcttag cattgggata cctcgtattc aagcgaaaaa atgtatgatg gttcattaac
    15541 aaagaagttg tgacagaagt ggccagtttc aagaaatttc ggcttatttt tagaagaagc
    15601 tacttcttga acaccattta ttcaaaaaaa gaagcgatga cacgaatgtt gtcaccgctt
    15661 cttttttgaa taaaccacag gcttcacagc ctctctttat acttctatac gtgaagcatc
    15721 ccagtggcaa ataaaaccat tgcgattact ccgaccatcg tcacaccgat aagtaaaatc
    15781 ttatctaagt ggatatgttg tacaggttcg ttttgttctt tacgtgcttt gaggtaaaaa
    15841 taaatacctg gtaagaaaag aacaagaaca agcatcactt cattaaaggc tacaactagc
    15901 atggcccata cttgaaaagc acttgctaaa aaccctacta aaaattggac ccactctttc
    15961 cgctgataag aaagcttcat ttggtacagc cctaagaaaa gccacgtgaa gaaaatcgct
    16021 gctgtaccaa gtgtataagc aaagttatat gcactgtcag tgaataataa tgaaagtaaa
    16081 aagacattcg tacataacgt cgtcaatacg atagcataag ttggtgcccc atttttgttg
    16141 agttttcccc atgctttagg caaaagtccg tcctcagcca tattccccat tgtttcaatc
    16201 ggcaagattg tccatgagag ccaaacccca actaaagaaa tgatcaaacc gccgttgatc
    16261 acgaccgccc cccatttacc aaccatcatt tcaaatacat atcccatagc aggttgcgct
    16321 ttgatcgttt gcagctgatt catcgtcatt gtgccatatg gaagcatgga aaccaagacg
    16381 taaataatga tcaaaccgaa tattcctaga atcgttgctt tcccaacatc cgattgtttt
    16441 tttgctcgtg aacctacgac agaagctcct tcaataccaa cgaataccca gagcatcacc
    16501 atgatgcaac tcaatacttg actagaaaac gggatcggct gcccattcgc attcaatatg
    16561 atatcgctag aaaagttatt aatgaattgt tggatcgaaa aggtgctgat agctactaca
    16621 ataaataaaa ataatggcac taatttacaa aatgtgacga tagcattgac aaagctagca
    16681 ttttcaactc cacgattcac tagccatgca tatccccata agaagatcgt actcatcacg
    16741 atcgatgcca cattttgacc accttcgaat acggggaaga aataacctaa tgcactcatc
    16801 aacaatgttg cgaacgccac gtttcctaac cagcatgtga gccagtaacc ccaaccgctg
    16861 ataaaaccag cgaaacggcc aaaaccttct tctgcgtaac taaagatccc gccttttaaa
    16921 tctggacgtt ttttattgat attattgatc gataaggaga gcatcaacat tgctgttcct
    16981 acgagtaccc agctgaagat agctgggcca ccagccgatc cggagatgtc cgtcataata
    17041 ccaaatacgc cacctccaat cgctgaacca atcactaagg cagcaagtgg aatcaaacca
    17101 attccttttt tctgttgctc tgtatccatg taagcatcct ccaaagtaaa accgctttta
    17161 tcaaaaagta taacaaacct tttttatttt tacttaatta ataaaaactt taatagaaat
    17221 ataattctac cgactttttt ctcattatac aagcaaagcg cctagtccct ttccaaatta
    17281 caccaccaaa aaaacttaaa aagatgctat actaaaggga aagaattggg ggatgatcca
    17341 tgaacatttt atatatatcg atttcaggaa atacgcgtgc ttttgccaaa catctagcag
    17401 aatatgctga aaaaatgcat gcagaagatc ctgtcaatcc tgaagttact ttaaaagaaa
    17461 tccatgaaaa tagtgatttt acgaaagaaa cagaaccatt ttttactttc gttcctactt
    17521 atttagacgg cgggaatggg ttagacaacg gtgacacaga aatcttgacc gaaacgatgc
    17581 gcgaatatct ggaatacgaa gacaatcata aactttgcct tggtgtagtc ggtagcggta
    17641 ataaaaactt caacaatcaa tattgtctga cagccaaaca atacgcacaa agattcggct
    17701 ttcctttctt ggcagattat gaattacggg gaacaccatc tgatgtgaca cgcgtttatc
    17761 aaattttggc agaaaaaaat aaataacaca aaagaagaag ctgaaaaata aatttcggct
    17821 tcttcttttt atgttctcta ttgtttctat tcttattaag ctttgacatc catcacaggt
    17881 gcttttgctt tcgctttacc tgttttttcc aagacaaagt tttttacacg atccatattg
    17941 gttaccaaga cgatcatgga ggtttctttg tctgctgctt tgattgcttc taagtcagct
    18001 tctgctacaa gcgtatcagg tgtcacttgc tgtccttctg ttactttcac atcgaatggc
    18061 gtaccgccta agtcaactgt gttgatgccc atgtgaagca agatttctaa gccatttggt
    18121 gtcgtaatgc cgatagcatg ttttgttggg aaaacagaac ttattactcc agtaaccggg
    18181 gaatagatat gtccgttttc tggttctaca aagtaacctt cacccatcat tttttgtgca
    18241 aaaactgggt cacttgcttt atctaaagaa acaactgttc cgtcagcaac tgatgataag
    18301 atagtcacac tttcagctga agcttgaggt actgcttttt caggtacttc atttactgtg
    18361 gctgtttcgg tcgctagttc ttctttttct aaacggtctt taggaatacc gaagaagaat
    18421 gtagcaacga agccaccagc gtaagcagcc aataaaccaa ggatatagcc taaccattta
    18481 ccatcagaga tcaatggaat caaagcggct cctgaaggtc caatagcgat tgctccgaca
    18541 tttccgatca ttccgatcac tgccccaccg atacctccac cgatacaagc agtaataaat
    18601 ggacgtccta gaggtaatgt tactccgtaa atcaatggtt cgccgattcc taagattccg
    18661 actggtaaag cccctttgat catttctgtt aattctttgt cttttttgca gcggatccat
    18721 aatgccaatg ctgcacccac ttgtcctgct ccggccatcg caaggattgg aagcaataag
    18781 gtacgaccag tttcatcaat catttgtaca tggattggcg tcaagatctg atgtagtccg
    18841 aacatgacca ttggcaagaa taatgtacct agaacgaagc cggcaaatgc tcctccaaca
    18901 ccaagtaccc agttgatccc accgaccatg ccgtcagaaa tgaaccctgc taaaggcatg
    18961 atgaagaaaa tttcgatcag accgatggca atcagggaaa gagttggcgt aacgatgata
    19021 tctaccgcat caggtactac tttatgcagt tttttctcaa cgattgacaa taaccaaact
    19081 gcgaagataa cacctaagat cccgccttgt ccagttgcaa gagcttcacc ggtaaacaag
    19141 tttttcagtg gtgcttctgg attcatccct gtcagcatca caacagcccc gataactcca
    19201 ccaagcgttg gcgttgcacc aaaaacttgt gcagcattga tacctgtata gataactaga
    19261 tagctaaaca tcccgttttt caagatgttc atcacatcga tatattgttg ccatgttcct
    19321 gcgtctagtg ttccagctgt gactaagttt gctaaaactg cggcaatccc tgccacgatc
    19381 ccagtgccga caaatgcagg gatcattggt acaaagatat tagagatgtc ttttaatacc
    19441 gatttgattt tagagggttt ttgtttcgat ttttgtgccg ctttcatttc ttgtgcccgt
    19501 tcgtttacac ggtcttttcc agatgcagaa gaacttgctg tagttgcact agcagaagga
    19561 agtttttctc ctaatttcac gcctgctaag tcaaccattt cctgcgctac tttgttcact
    19621 ttcccaggtc cgatgatgac ttggagctgt tcatcctcta ctacgccaag tactcctgga
    19681 atcgctttta attccgagac atttacaaga tcatcattga tgaccttcat acgtacacga
    19741 gtcatgcagt ggacaatgct ttcaacattg cccataccgc ctgctccttg ataaatttgt
    19801 tttgccagtt cttccaaagt caattcgttt tttgccatgg tcttttcccc ctcataaggt
    19861 tccttttaca aaaccgtttg cttcagctaa ttttgcttga gctgcctctt tatcactatt
    19921 tgtcaaaatc atgacgatag ccagtttgac attttgatct gcttcctcaa agtacttttc
    19981 agctgtttcg tagtcagctt ctgtcgcttg catgatgatt cgttttgagc gttcaattag
    20041 tttttcattt gttggtttga cgtcgaccat caagttattg aatactttac cgataccgat
    20101 catactgata gtagaaatca tattcaaaat cagtttttgt gctgttcctg acttcaatcg
    20161 agtagagcct gtcaaaaatt ctggtcctgc atcgacttcg attgggaaat ccgcatgctc
    20221 gctgatttct gcttgtttat tgcaagaaat cgttcctgta acagcaccaa tcgattttgc
    20281 gtaatctaat ccaccaatca catatggtgt acgaccgcta gctgcgatac caataactat
    20341 atcatttttt gttaaattca gcttgattag atcttcttgc cctaattcat aagaatcttc
    20401 ggctccttcg acggctacag tcattgcttc ttctccacca gcaattaggc ctatgaccat
    20461 ttccggttct acaccgaatg tcggtacaca ttcagcagca tctaatacac caagtctacc
    20521 actcgttcca gctcccatat aaatcaagcg accacctttt ttaaaggatt caatcgtgtt
    20581 ggcgatcact ggctcgatac ttggcagttc tttttcaaca gcagcggcca ctttctgatc
    20641 ttctttgttc atgagttgga ctgcttgaga aatactcatt tcatctaatc caaaagtttc
    20701 ttggtttctg cgttccgttg ttaggttctc taaattgatt ttgctcattt ttatcttcct
    20761 tcttttctta taaattgata gttcatacca gctttgattt ggttgatcag cggtagttct
    20821 tctttgatga ctttggctac tacattcact ttttcatccg ctggcaaatc atatttagtt
    20881 aattggatct cacccatata gcgcaaatac ttttcgttat ctaaagtaat agatcctttc
    20941 atacgcttag ctgtatttct tactgggatt ggcggaatct ctcgaaaacg cgcatctgcg
    21001 cttcgtatga catctcttgc atcatcttgc cgattcgtat gttttcctaa tatatattcg
    21061 taaaaaactt catctacagg ttccgtatgg agcaagactg tctgttcttt ttggaaagaa
    21121 gcaaattgct cctgaacgtg ttctgacaga cctgcatctc cgatataaac aatatccgtg
    21181 ttacttgcta atagatcaag agcacctgcc agaggatgga tccctcgatg ttcttccaaa
    21241 gttggtaatc cttgatacag tggacctctc aactctgtat ctcctggtac aaagccttgt
    21301 acaaggaatc cttgagtttt gagccattga tttttttcct gataccattc tttgtccaac
    21361 cctgtttcaa gacgtggata ataattatgc caagcttcaa tctgtgagaa atcagccgct
    21421 gcttctttca actcatcgat atcattaggc gtgatcgtgc tggcattcaa actgattttc
    21481 aattgatgtg accagtcggc gatctgctga ttagaaatat gataatccat tcttaaccct
    21541 gttacaccaa ttgctttcaa gggtgttaga tcttctaatg aaaagccagc tcgtttcaat
    21601 gcctctcctg aaatatcgac catcaactct agtttattct ttttcgcttc gcttcctagt
    21661 tcgatcaatc gattttgata agccgaaaca tcatcttccg gtatatgcat ggaagtgaaa
    21721 ataccgacaa agccattgga tgccatttgg cggatatact gtttcttctc ttctgacaaa
    21781 gaatcattca taaatattga aaagccaaac atattatccc tctttttctg tatccgtctt
    21841 catttctatg actagagtat atatctaaag aaacaaaatt tcaatacttt tgttaaaata
    21901 attaaatttt atttctaaaa attggattta taatgccaaa agaattgaca cagccacaaa
    21961 aaaggcactg ctaagcaaaa gcagtgcctt gaaacatttt atttaaataa cacaaaagtc
    22021 taattactca taagaaatta attctgtatt gtctaccatg aatgtaaaga acccttcatt
    22081 aggcattgga tgaaaataag cattgatcac tcttatcaag gcattatgac agactaacaa
    22141 gtagacattt tcttcgtctt ccatgcattc tttcaataaa ggaacgatcc gtgcgtacac
    22201 atctaagacc gactctccat ttgggaaacg tacagcaaac gctaaacgcg ctttttgaaa
    22261 gttttcatct ttgcttggca gtccgtcata atccccaaaa tccatttcta ccaatcgctc
    22321 atcagcggtc atcggcaaat tgagacgatc aactactgct tgtgctgtat ctcttgctcg
    22381 ttgaagaggg gaatggatga ttttcgtgat tggaacaggc aaatctacta ccttttctgc
    22441 tagtgcctgt gcctgcatct gtcctttttc agtcagcggc acatctgctc gcccgcaaac
    22501 taatccttgt gcgttccaag ttgtttctcc gtgtctcgtt acataaagca tgtgattctc
    22561 tccttcgttg acaaagttct ccttaaccat accttgttgt ctttgagatt acaaggttta
    22621 gattttctca agagaaataa tctcagtaga tactttatct agaaaggttt gatcatgttc
    22681 cactagtaac atagcaggtt tcacgttcaa aatcagttgt tctaattgtt cttgattgaa
    22741 gacatccaaa taattcaatg gttcatccca tatatagagc tcagctggtt gggataaaga
    22801 tttagccaat tccacttttt tccgttgtcc catactcatc tgttcgattt tattatgaaa
    22861 aacatctctt tccatcccaa gctttcggag attattcaaa aatgcttgat agtctactcg
    22921 gtttttcttc gcgaattccg ccaatgtccc tcgattgtct tcataatttt ggcgtacgta
    22981 actaatggtc aaatgtttgg gctgggattt ttctcctaca accttgccgt tgaatgtccc
    23041 cagaagataa tggataatgg atgactttcc cgcgccgtta ggacctgaaa ttgccatccg
    23101 ctgatgaggt tcgatcgtaa aatgaactgg ctcgaataac agattttcat accctaattg
    23161 aagattttct acgcttaaca gccgtttatg atgagacact tggctattca tcgtcaaagc
    23221 atcgatatac tcgatatctt ttaataattt ttctttctca ctgatctggg tttccatccg
    23281 attcacgatt gctttagatc gtttcatcgt ccgtgcagca tcagcgccta ctgctccttt
    23341 attcactcgc ctagattccg tatcgatgaa tccgactttt ttctttgttt tgtccccttc
    23401 tcgggaacga gaccattctg ctttttcagc tgctgttttc tttagcctgc tgacttcttt
    23461 tttcaatttt tcatttttag ctatttcaaa ttcatcacga agttttttct gttcttcata
    23521 gatagagaaa ttcccttgat aaagttccag ttggctcttt tcgattgcta aaacatggtc
    23581 cactacttca tcgataaatc cccgatcatg actcaccacg atgaatcctt gttttttctt
    23641 tttcaagtaa gccgctactt gttttctgcc agagatatcc aaatgattcg ttggttcatc
    23701 gattaacggg aaatgagtgt catccacaaa taagagtgcc agtaggactt ttgtcttctc
    23761 tcctcctgat agtgtgctga attctctcca taagatttca ggatctgttt gcatcagttg
    23821 gagctctctt tcaatttccc atatctcaaa atccataatc tcatttaaca cataataggt
    23881 caaacgctct ttatcttttg tttgctgcgg gaaatagaca aacgcttgct gatggatcac
    23941 ttgcccttga taagggagtt tgttttgcag gatattcagt aaagttgtct ttcctcgacc
    24001 gtttcgtccg ataagtccta gtttccattg tgtgtcaaag tttagattgg cttgttcaaa
    24061 taataatgtg ccttggctgt catagccgaa tgtcagattt tttatttcga ttttagacat
    24121 tattccatca cctcgtaaaa aaagaccagt cctattttca gaactggcta aagaggatgc
    24181 aagggttggg gcacacaaaa agacccatac atcgaaagaa ccaagccaat cccgaaaatc
    24241 tgcacactgc tcccttgtct ccacaaggta cagtctgaat gcagctttca tcaatcgact
    24301 taatttttca atgcacggat ccctcacttt gtcctatatt tgaaattacg atagcataaa
    24361 gaaattgttt ttgtcaacta cttcgggaga atgttgaaaa atctgctgag tgtctgtcct
    24421 aagatttctg ttttttctaa tgtttgcctg tgttccattg cttcctctaa atcgattggt
    24481 cctaattgaa tgcttaagac aatggggaga aaatcaaaga gtccttccag ctctcggtct
    24541 ctacttccgc aaatagcgat tattggtttt cgatattttt ttgcaagcac tgctacgcca
    24601 tatggaactt ttccgtggat tgtttgctga tcaatccgcc cttctcctgt aatgatgaca
    24661 tccgcttgtt cgatctgttt ttctaatcca gtgatttggc tgaccaactc aaaaccagag
    24721 accatcttcg ctcctaacaa aaaaagggct ccgccaatac cgcctgctgc tccgcttcct
    24781 gggatgtcat ctaaatccac ctcccaaaca tcttttatct gctgagcaat cttttcagct
    24841 tgtttatcca agaaagctaa cgtcgtatcc gttcctcctt tttgtcttcc aaattgccaa
    24901 gcagctcctt gttgacctgt atatgggttg gtcacgtctg cagcgatgat cacttttact
    24961 ttagaaacaa gaacgttcct tcgatccaaa tgaagttttc tagtagataa caaaggattt
    25021 ccttctgtgt acccttctaa agaagcaccc aaagattgga gtaatcctag accaccatcg
    25081 ctacatccgc ttcctcctaa agtgacaatg atttgttcca cttcttgaag cagtgtatct
    25141 ttgataagct ctcccaaggc ataactagaa gcaagtcgga tggtttgatc cgttggttta
    25201 tcaagtaaat ctaatcctaa tacttgtgca gattcaatga ctgcggtatt ttttccttgc
    25261 cagttcgtca ataaataact gatttttcgc tgacgaaata agagatccat cccatcaatc
    25321 gtacgccagg ttcccccgag cgcgtaatag attgcttctg cagtattttc tccgccatct
    25381 gcaatcggca cattgatttt tcttccttta cggtcttccc aaccatttag aactgcctga
    25441 tttaattcaa atgaagaagc acttccttta aatgaatcga ttgccgccaa aatatccatc
    25501 tatatccctc actttcttct taagtaagac actttttttc acttttttca aacaaaacaa
    25561 tgctattttc ttctgttttt ctatatacta aaagggaact cattgaataa aggagagaaa
    25621 aaacatgaaa atcgcaatag ctggagccgg agcaatgggc agccgaatcg gattaatgtt
    25681 gcatcaaagc ggaaatgagg tcgtcttgat cgatcgctgg cctgctcaca ttgaagccat
    25741 tcgtacaaat ggattgattg ctgactttaa tggcaaagaa gtagttgcaa aactgccaat
    25801 ctattcacca gaagaaatca tcgaaagcaa caaacacgtg gatttgatcg tagccttgac
    25861 aaaagcgaat caattagatg atatgtttcg ttcgatccaa tccattatta ctgagaatac
    25921 ttatgttttg tgtttactga atggattagg tcatgaagat gtactggaaa aatatgtacc
    25981 aaagaaaaat atcttatttg ggatcacgat gtggacagct ggtctagctg gtcccggaaa
    26041 agtcacatta ttaggtgatg gagaaatcga actagagaac ttggaaccag aaggcgaagc
    26101 atttacaaaa aaagttgtag aagtctttca agaagcaaaa ttgaatccaa tctatagtca
    26161 taatgttcgt tattccattt ggcgaaaagc ttgtgtaaac ggaacattaa atggattatg
    26221 cacgatattg gattgtaata ttgctgaatt aggtgcgcaa aaagcggcag agggcatggt
    26281 tcgaacgatt gtatctgagt ttgcttctat cgcagcaaaa gaaggaatca cattagatca
    26341 agaagaagtg taccaacata ttgcttctac ttatgatcct gacaacatcg ggttgcatta
    26401 cccatctatg taccaagacc tgatcaaaaa ccatcgtttg actgaaatcg actacatcaa
    26461 tggtgccgtt tggcgaaaag gacaaaaata tgatattgct acaccatatt gtgccttttt
    26521 gacccaatta gtccatgcaa aagaaggaat ccttggcgca gaataaaagg ctctctgatg
    26581 agaatcagct ggatcagcag ctggttctca tttttttacc cccatgaaag ttcaaaaaga
    26641 aaaacacaat tctcatgttg ccataagaat tgcgcttgtt tattttcatc tatgattggt
    26701 tggcactttt atttattttt aacagaggaa agatcgtatt catattgttc ataaatagcg
    26761 gagtcagtag tgaaaaaacg ttttgcccaa ttttctgcat caaaaaattc caacagttct
    26821 gatgggattg gttgaaatgg cgtatgcaaa aattccggta attcatctaa atcacgttct
    26881 tgaagcaaaa aaatattttc agaatgataa aactgataat gagctatggc ttgattatct
    26941 gtcactagtt tcttttgaaa atacatagat tcaaacgttc gcaaagtcac tccttgctgc
    27001 ccttcccgca acagttctag aatccccctc gattccccgg tttttttcag atattcttca
    27061 taagtaaggt atccaggttg ttcatttcct cgaagcggaa gaataaagta attggtcgta
    27121 acacctcttt ttgtaaattc ctgcttatat ttttctgccc gttcttttct gccgttattt
    27181 gttgcaccaa aaaatagatc cgtctttggt tcgctagaag aaaaatccat atgtttcgaa
    27241 taaaaggaac tattatgttt tagtccaagt tctttcgctt ctaaaaaatc aaaatgataa
    27301 atctcatcga ttgccggttc atcttgtgcc tgcttcagca tcgcctcgtg ttctgcttta
    27361 aagtggttcc aaaaaaataa cacgattttt gcattggtaa atggacgcac gcgtcgagcc
    27421 atctccatat caaatccata atctaaaaaa acgatcagct gataatttgc caactgttgt
    27481 cgagctgatt taatgaattc cgactgtagt aaatcttttc cggaccaaac atctaaagag
    27541 cggatggaag gaaaaaaata aagtgattta tttttcgcaa ttagcaatac gtcgtttttg
    27601 ttcatctgtt ccgcctcact ttctctgtca ctttttccta tgatagcctg tttaaatagt
    27661 aaaaagccag taaaacgctt cctattattt ttataaaaat ttaacatttc tatgaaaata
    27721 cgatgaaata aatcattctt ccattaaaat atgcccaaaa gttttctgaa tagttgtaat
    27781 tatctgaaaa tttgttatca ttagtcatta ttattattac tatttattct tactatttat
    27841 tcttactatg cattttgatt gtgaatttaa aagaaagagg ttatttatgg aagataaaaa
    27901 attgaaaaaa caacttagct cccgacatat caccatgcta gctttaggtg gagcgattgg
    27961 tgcaggtcta tttaaaggaa gtggcgaagc gattggaatc gccggccctt ctgtattgat
    28021 cgcttttttg attggcggca taattttata tatcgtgatg aaaggtctgg gaaaaattgt
    28081 tttaagtggt ggtgatacgc accacggatt atctggattg attcgtccat atctaggtgc
    28141 tcatgctgcc gattttaccg attgggtcta ctggtccatg tggattatca atatcattgc
    28201 tgaagctgtt gcagctgctt cctttttaca gttgtggttc ccccacatcc cagcttgggt
    28261 atttgttttt atgttggctg ttttaactac tatcatcaat ctttattcgg tacgattatt
    28321 cgcagagaca gaatattggc tggcctttgc taaaatcagt gtcattatcc tattgatcat
    28381 ttttgctgct tatcttgtcg gtcagcaaat gttgggtact ggtgttttcc ctacccttca
    28441 acaattaact gatcatggtg gttttactcc ccacggtatg aagggaatca tcagttcttt
    28501 gcttgtagtt atctattctt acggcggttc tgagttgatt gctatcacag taagcgaagc
    28561 agatgatcct aaacgtgcga ttcctaaagc aatcaaaggc gtcatgggaa gaatcatttc
    28621 cttttacatt attcctttat ttttgctttt gattattttt ccttggaata ctttagcagg
    28681 cacgaacgtt agtccttttg tgatggtatt tgaaaaaatg aatattccat ttgcggcaga
    28741 tatcgtcaat ttcgtgattg ttcttgctct gttctcgtct atcaattcag gtgtatatgc
    28801 ttcttcgaga attttgttct tccgcttgaa agatcggaaa ggttcctcta gaaaactagc
    28861 tgttttaaac aagcatcaag taccgcaacg tgctgtgctg ttttgtacca gtgttcttta
    28921 tctaggtgtg gctctttctt attttgtcgg tgacaaatta tttggctatc tggcaggttc
    28981 tctttcctat acagtattat tgatctggat cattatcagt gctgcgtcct ttgtactgac
    29041 actaaggaaa ggaacgttat gggacaaagg aatcagcttt tttgcattag cagtcttatg
    29101 gttgattttc cttggtatcc tattcacgaa ctccattggg gtaactgtat tgaccggttt
    29161 gctttacctg ttcatttatt tcagttatca aaaaaagaat gatgctttcg tcttgacgaa
    29221 tgaatgaaac caatagagaa ttttattcta tttatattga atatctggag ctattgaaaa
    29281 aaaggagctg cgacaaaaat tgttgcagtt cttttttccg aataaacggt gttcaaaaac
    29341 catctgtgca gattaattga ttgttctcca cgctcatgac atgatagaag aaaggaatga
    29401 agaaaaagga gtttgtttta aatgaaaaag tattggaagt ttttgttgat gattggtgtt
    29461 tcgacggtag tcatgtttgg tatgatgtat ttgaatgttt atgcgcttga tcatatcttc
    29521 ttcagtcgca cacgtgtatt catggcgttg atgatgggtg cagtcatggc agtcatcatg
    29581 ttgttgttca tgtggaaaat gtatgaaaac aaaaagataa atgctatgat tttagccgct
    29641 agtcttcttg tttttgccgg ttccttattt atggtacgaa gccaaacaac tgtcaacgat
    29701 acggcgtgga tgaaggcgat gatccctcat cactctattg ctatcttgac aagtaaacga
    29761 gctgatttaa aagatcctga agtaaaaaaa ttagcggaag aaatcattca ggcacaagaa
    29821 gaagaaatcg acaaaatgaa aaaaatgatc aaagaaatgg aatgaccatt atccatccaa
    29881 ataaaaaaag aggatgttcc agaagtgatc aacttcaaga aataagaaga agctacttct
    29941 ggaacaccgt gaatcagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
    30001 aaacaaaaat agcttctcat atttttcgtt tggttaggct tattaccgca aatgcaagct
    30061 tttgaacacc gtttattcgt aaaagggagt gtgacaaaag tcttgtcaca ctcccttttt
    30121 acgtttttat tgttctaatt gcgctgtctt gcttactgct tcttgcggtt tcacaaattt
    30181 ctttgagatc ccccaacctg taaaggcact gaccatcgaa aacacaggtg aaagcaaact
    30241 gaaaaacacg aatggcaagt aagtgagtgt aggaatgcca aatgtacttg ctacgaaact
    30301 tccggcgatt ccccaaggca ctaagtagtt gattactgtt ccaccatctt ctagtgttct
    30361 ccctaataca gttggatcaa atcctgcttt ttcgtaagtt tctttaaatg cattaccagg
    30421 caggataaca gatagaaatt gttctccaat aaagatattt actccgatgc ttgtcatcaa
    30481 tgttgtaaaa atcaattttg gggtgttcgt catctttctt gatactcgtt ccataacggt
    30541 tgagatcaac ccaaattcga tcaacaaacc acctaatgac aatgttagaa taatcaatga
    30601 cacagttggc atcatgcttt cgattcctcc acggctaagt agtgaatcga tttgttggtt
    30661 tccagtattt gaaacaaatc ccgattcgat gacccctgcc aacttcgtta aggaagtttg
    30721 tgggttttga ataaagatca ttcctactgc tacagcaata ttcaacaaaa tcgtcaaaat
    30781 tgccggtacc tttttccatg cacacaagag cattaaaaat agaggaatca gtgaccagat
    30841 cgaaatagta aagtttgctt ctaaaatatc agtcacttca cgaatagatg aaagacttgc
    30901 ggctttactt gtgtgtccta aaatcatgaa taaaaagaaa gaaacaacaa atgccggaac
    30961 agttgaccac atcatatgct tgatgtgttt gaacaaatcg gcatcaacaa tagctgctgc
    31021 taaatttgtt gattcggata atggagacat cttgtctcca aaaacggcac ctgaaacaat
    31081 ggctccaaca acaagggctg gatttagtcc tagtgttgtc ccaataccga aaaatgcaat
    31141 cccaatcgtt gacataacag taaaggcact ccctacagcg ctacctacga ttgcacaaac
    31201 aacaaataca gaagggacga accactggac actaatcaat ttaaatccaa tgaccatgag
    31261 ggttggaata attcctgctt gtatccatac agcaatcaat gaaccgacta aaataaaaat
    31321 aaagattgga atgatccccg gtttgatgcc attgatgatc ccttcgtgca gccaatctgt
    31381 cgggtatttt tttatcactg cgtacaacat gaccattccg atagctgcca aaatcgtgat
    31441 attaggtgaa acctttaatc cgacaacgcc aatcgcaatg cctaaaacaa tgaccatcaa
    31501 tacaagtgtt gcttctaaaa aacttggtgt tccttttttt tccatgataa tctctccttt
    31561 tttagttgtt cttatgttct aaaaaagtta agatatcgga ttactccgcc acaattcatc
    31621 cgcgattcct cctttataaa aataaaaaga cctgctttca actaaggacg aatgactccg
    31681 cggtaccacc ttaattaaaa acagatctgt ttttcacttt caaacgatta ttcaaatgta
    31741 tggactttcc atgtaattcg tcaattaggc ttgatcggtt cacagcgacc accgactttc
    31801 tgaacaaaac acctaaccac tactgcgtga aaagttgact tgtatgaagt ttaccttcca
    31861 taagatcatt tgtcaatgaa aaagaaaata ttttttcatt tttctgaaaa ttatttttat
    31921 aactttcgcg cacaacttta tctttttact agaaagtagc gccctcttgt ttttttcttg
    31981 ctactatttc ttgatgttct tgtttgattt tttctaatag cttgggttct ctcaataaat
    32041 ctagagctgt attggcaagt aattccgctg caatcgcaat agaagcaagt cctttttcac
    32101 ttttagcagc agctttgaat tcttctgtat gtccggcaat atatgtctca gagattgcta
    32161 cagtaggctg tatcgttgga ataacttggc taacatttcc tacatcagaa gaacctagac
    32221 ttgttctttg ttccgtttct atttcttcat caggaacccc tgcttctttt gcatgttgga
    32281 agaataagtc atcgaaagaa ggcgttacga tgacatcatc gactgcattt tggaacaatc
    32341 caaactcaaa agtcgtaccc gtgcttaatg cagcacctcg tacgatattt tccacttttt
    32401 catatacttt gtctaatgtt tgtcgatttc ctgcacgtaa atagaaacgt ccagcagcgt
    32461 agtctggtat gacattggcc gccacgcctc catctgtaat gattccatgg atattgacat
    32521 cttttggcaa ttgcaagcgt agagcgttga ttccgttaaa cacttggatc aaggcttcca
    32581 aagcatttac tcctttttca ggtgctgctg ctgcatgaga agcgacaccg taaaatttga
    32641 tatcgactgg atcatttgct aaagattctg tcgttttccc ataacgaaaa gctggatgga
    32701 cacataatgc tgcatcgaca tcctcaaaaa aaccttcccg aacgaagctt cccttagctg
    32761 atccattttc gcctccttct tcccccggag taccatacac acgaatttct ccgccaatct
    32821 catcaatgaa ttgtttcact atgctggctg ctaatacgga gtaagtacca aataaattat
    32881 gtccgcatgc atgaccaata cctggtaaag catcaaattc tgccaaaaag gcaattgtcg
    32941 gacctggttt attggaaata taacgtgcat caaagcctgt tcggtgccca gctacttctt
    33001 tttctaccca gaacccttct ttttccaatt gtttgattaa agctgctgag gaataaaatt
    33061 cataattact tacttcagga tggtcgtgga tagctagtgc aagtgcttga tattctggta
    33121 aacggtattg aatcagatcc ttcaattgat ttgttgagag tgtggttgtc ataaaaattt
    33181 cctcctatgc tagtcgtttt ttcttatttt ctcccgaatg tttcccacgc aggtacgctt
    33241 gaaccttttg atgttttttc gattactttg gctgtttctt ctgtttgata ggcatctact
    33301 attttttgat acgttttatt gtcttcatct tcttttcttg caacgatgat attgacataa
    33361 ggacgtgcat gctcatcgac tggttctaag aagattgcat cagaagcggg attaaatcca
    33421 gcatctacag ctacaccgct attgatgact gaaatatcta catctgacaa agcacgtgct
    33481 gtttgggaag catctaactc agaaatgtct agattttttt tattctcggt aatatcagaa
    33541 acggtaggcg cttggccttt tgccttgtcc actttgatca atccagcagt ttgcaataac
    33601 agaagagctc tgccgccatt cgtgacatca ttagggattg caacttttgc tccatctttg
    33661 atatcagcca catcttttaa cgtattggaa taaattccca acggtgcatt aaccgtattc
    33721 ccaatcgata ctaaatcagt tccgtgttct tcattgtaat tgtctaaaaa gaattgatgt
    33781 tggaaggaat tcaaatcgat cgatccatct gctaaagccg catttggctg attgtaatct
    33841 gtaaatttca catattccaa atggatgttt tcctttttca aacggtcttt cacatcgtcc
    33901 catacatctg tatcttcccc aatgatccct agttttacgg tcgtttcttt tttttcagtt
    33961 gtagctgctt ttccttggct gcatcctgcc aaccaaataa ttgctacaaa tgtaatgact
    34021 gcaaaacgaa taattttttt cattttttct cctccatttt caatgtgtga cttttttaat
    34081 cagttgatta ctgataaatt gactcaaaaa aactaagacc agaatcaata atgtagcgac
    34141 aatcgttaca tctgtttgga atcgattata tcctctcgat atagcaagat tccctaatcc
    34201 tccggcacct actgctccag ccatggtagt cagtccgatc acattgatga tcgtcaacgc
    34261 tgagacccga atgataccag gtaacccttc taacaaataa acacgtaaaa tgatgccgat
    34321 tgggctcgtg cccatcgctt ctgctgcttc gatcacccca ggatcaactt ctagcagtgc
    34381 attctcgatt tgacgggcaa aaaacgggac aacgccaaaa atcaaaggga ctaaagctgc
    34441 tttggcacca atcgtcgttc caactaagaa acgagtagtc aaagctaaaa gagaaagcaa
    34501 gataatgaaa gggatggaac gaatgatatt gatcaactta tcaagtattt cgaacagcag
    34561 cctgttagct agtaatccat ttggacgtgt cactactaac gtcacaccta agatgattcc
    34621 gatgatccca ccaatgaatg ccgtccaaaa agacatatat agtgtttgct ttgtcgcttc
    34681 gatgaattca tccggaatca aatagacatt cggcaaatat gttttaaaaa attcagtcat
    34741 tttagtttcc tccttcgatg actttgatac ggttatctaa ttcatttttt tgtaaaatag
    34801 ttacttttac accagattta atcaaataat ccaatgcttt ttgccgctgt ttggtttctc
    34861 cagctaaagt aacgatcaaa cttcctaagg gtgtttcttg taatagctct acattaccgt
    34921 ataagatatt cgctgttact tggtacttgc tgtaaagatg agcgattaga ggttcgttcg
    34981 tctggttgcc gatataactt aattccacca accatttatt tgcaatctga tcggcaaaag
    35041 cagcatgggc actgattgtt tccaatgctt ggtcaaggtg tgtcgctgtc cgaataaaat
    35101 ctttagtcaa ttcttcttca ggatgactga aaatctggat gctgctacct ttttcaatga
    35161 ttttccccgc ttccataacc gctaccttgt tgcagatttc tttgacaact tgcatctcat
    35221 gagtgatcag gacgattgtt agacctagct gacgatttag tttttttaac agtgcaagga
    35281 tctgaagggt cgttttcgga tcaagtgcac tagttgcttc atcgcataac aacactttag
    35341 gttcatttgc cagagctcgt gcgattgcca ctcgttgttt ttgccccccc gacagttgtt
    35401 taggatacgc agatgctttt tcttccagac cgacaagttc cagtagttca ttcacttttt
    35461 gacgacgttc ctgttttgat tttccagaat actttagaga aaaatctacg ttgtcaaaaa
    35521 tcgttcgact ttccattaga ttgaaatgct gaaagatcat accgatggcc tttctttctt
    35581 ttcgcaattc ttttggagag agctggctta aattcgtctg attgacgatg acttctcctg
    35641 ctgttggttt ctgcaacaaa ttcatcacgc ggactaacgt actctttcct gcacctgagt
    35701 aaccgacgat cccataaaca tccccttttt caatcgttaa atctacagaa tctactgcct
    35761 gtatctcttt ttctttttgt ttgaaacata cagaaatatc tcgcaattca atcattaaca
    35821 ttcctccttg tctataaaaa aagcatcctc aagaaaatga aaatagtcat tttcttgagg
    35881 acgccttttt gcgtgttacc acctcatgtt caagctgtgt tcacacacaa ctcctcttca
    35941 agtaccatca tactctagca agatatcggt cgcagccgtc accgccttac atctatgctc
    36001 gggatgaatt gctcgatggc cattttccaa tagtcgttcc ttgcttcttc tcagctaccg
    36061 aagctctctg tcaaaggttc ttctatcgta cttaccattt caatgcaaat aatattcaaa
    36121 aaaaaaatcc ttttactaac ataaactatg tcagtaaaag gacgacgtat cgtggtacca
    36181 ccttttttcg gaagtttcct tccctcaagc ccaacatctc aaaaagagag attggcgttc
    36241 gttttaacgg tcgaacattt ccgaatttgc ctacttatcg acaaattatt ctccaaggcc
    36301 attttcagct tttcttactt gactcttcac accagccaga gcctctctgc aaagtttcca
    36361 agcttacttt ccttctcaac gaaatcaata ttttgttgtt gggaataatc tacaggagga
    36421 aaactgaaaa gtcaagcatg aaatccaaat tattttttct atatttattt ttctgttttt
    36481 ttatctaaca tttcaataac agttcgaaga tcttttcctt ccgcaagaag gttcaatttt
    36541 tccttctctt cgacgctata atttcgaaca aaactggaat cgggaatcaa aacaacgcct
    36601 agtcctgcac gtgaagcggc tgtcgctcct actaaagaat cttccactgc aaaagctgaa
    36661 agagcttcta atcctgttcg ttccaaagct gtcagataag ggactggtga aggcttgttc
    36721 tccgatactt catctccgaa cgtaaacgta tcaaagtaat cggctaattg aaagtgatcc
    36781 aagatatctg ttgctctttt cgtaacagtt gtcgtagcaa tccctagttt catatgacgt
    36841 tcttttaagt ctgtcaatat ttcttttgca tagggtttca attggatagc tccacttgtc
    36901 agctgttgat aaaaatattc ttcacgcttt gctcggactt cctgcacttt ttcaggactg
    36961 cctgctgcct gcactaaaat atcaaaactt tgtttccatt tttttccgcc ccaagcgtca
    37021 acgatttctt tcgggatatg aatatcaaat tgctggaatc cccaaagcca accatcccga
    37081 tacgttcttt ccgtatccac taacaaacca tctaaatcaa atattgcacc tttcatctat
    37141 acattaatcc tttccaaaac aatacaccta gtttagcatg actgatccaa aatgaacaga
    37201 agcatagagc ccagccgcat cacttataag agttcttgga atcgacggat atagattttc
    37261 ttcacagctg tcacaagcgc cagataagcg acgactgtta taaaaaacca taaccagtaa
    37321 ttgccaggga gcggcatcaa gcctaactca gcaccaaatc ctgtgaatgg aaggactgaa
    37381 ccgacaatga ttcctaatgt agtgataacc agcatggcaa atgttgcatt gctttggata
    37441 aatggtattt tcggtgtacg caatgcatgg agtactaatg tttgtgtcca cagggattcg
    37501 acaaaccatc ctgcatggaa taatgcgata aaaatcactt gttgtgagct atccaatgta
    37561 tggaaacttc caccaactac agcaggacaa ataacaaaat acatcaacaa gtaagtagtg
    37621 atatcaaaaa tcgaacttgt tggaccaaaa taaaccatga attttccaat actagatgca
    37681 ttccatttct ttggctcatc caaatattct ttatccatcc gatcccatgg taaggaaatg
    37741 caagaaacgt catagatcag attcaaaaat agaagttgca aaggcaacat tggtaaaaat
    37801 ggtaagaacg tactggcaat cagtacggaa aacatattgc caaaattaga acttgctgtt
    37861 gccttgatat atttcatgat gtttccaaaa gtttctcttc cagaaagaag gcctctttcc
    37921 aaaatcgtca aatctttttc taaaaggatc acgtctgctg attcttttgc gatatccaca
    37981 gctgtatcca cggaaatacc gatatcagcc actttcattg ctggagcatc attgatacca
    38041 tctcctaaaa atccgacagt atgcccattt ttacgtaaag ctgtcgtcaa tcgtgctttt
    38101 tgctgaggat tcaattttac gaatacttcg tgttcttcag ctacttgcgc taattcatga
    38161 tcattcattt ccgagatttt ctcaccagta atcaattcat tgatttctag gcctacttga
    38221 cggcacacag accgtgtgac taattcattg tccccagtca gaacttttac agctacacca
    38281 tgttctttta aagctttcaa cgcttgtttt gttgtttctt ttggtggatc aaggaaagca
    38341 agataaccaa tcagaaccat gtctgactca tctttgactg aaaattctcc aacaacgctt
    38401 ggattggtct tttgtgcgac accaatcact cgtaagccgt cttcattaag tgattgtact
    38461 tttgcaagca ccgcttcttt tcgttctttt gttaatggtg cgacagtacc accaagatca
    38521 ataaatttag aaatgttcaa catttcttca atcgcgcctt ttgtgatcat ctgtgttttg
    38581 ccagccggat cagcgactac aacactcata cggcgacgtt caaaatcaaa aggaatttca
    38641 tctacttttt gataattgat tgtatctgta tctaaagttt ctgctgcttc atcaatgata
    38701 gccacatcta acaaattttt cagccctgtt tgatagtagc tgtttagata agcatggcgc
    38761 aaaacacgat catcttcatt tccttcacaa tccatatgat attcaagaat gattttgtct
    38821 tgtgtcaatg ttcccgtttt atccgtacat aacacatcga tcgcaccaaa attctggata
    38881 gcatttaaat ttttgatgac tgttcctttt ttggccatca cacttgctcc tttgaccaaa
    38941 ttcgtcgtaa cgatcattgg aagcatttca ggcgttaaac caactgccac agataatcca
    39001 aaaagaaaag cttctaacca atctcctttt gtaagcccat tgataacgat aactgctgga
    39061 gccatcaatg acataaattt gatcagcagc atggatgttt tgtggatgcc taattcaaaa
    39121 cttgattgga tgggtttttc agatagcgtt tctgctacat gcccaaatag tgtgtcattt
    39181 ccgacagaaa caatgattcc ttccgcgctt ccactgatga cattgcttcc cataaagaca
    39241 agattttcat aacttgtttc actttgctga tcgtcttcac atactttcgc atgcttttct
    39301 actggatagc tttcccctgt caatgctgct tgagaaatga atagatcctt tgcggacaat
    39361 aaacgcatat ccgctggtat catatctcct gctgaaagcc gaacaagatc tccacagacg
    39421 atttcttcca taggaatctc tgtatactcg ccatttcgtt tgacagctgc cgttactttc
    39481 acaagtgatt tcagtttttc agctgcttga ttagaacgca cagactggat caacgtcatc
    39541 gtcccactga cgataaccat agtgaagata atggctacac caaagagatc tttatctcct
    39601 ggagcggcta atacgtattc cgtaatgaat gaaataattc ctaatgcaat caacactaat
    39661 gtaaagggtg tgatgtatgc tttcaatatt tctataatga atggtgtttt tttgccatat
    39721 gaaatcgcat tttcaccata agtttctctt gaacgctcga tttgttcttc tgacaatcca
    39781 tttggtgatg catggaacaa ttcaaataat tcttgcttcg tttttccagc aaaagctgca
    39841 tagatttttt gtgtatcttt ctttttttcc atctcgatct ctcctttgtg tccaaaagac
    39901 agctgttctc gctgtttttg gtcttttgct attcatcgga tcgatagaga aaatgctgaa
    39961 aggggctgag aacagataga taatagccct ggcctttcct ctaaatcctt gtttttcgaa
    40021 tgactgtcat ccatttgttc tcatctcctt tactaagtaa ttttaattca tgacttccaa
    40081 tcatttttcg aatagttatt ttcccaactc gctcacctcc ctttttgttt tttcacctat
    40141 gggatttgcg gcaacaaaaa aacctctcgc caaatactca gcgaaaggtt tgaaaaagca
    40201 aatcaaaaaa agcttctcag atctcatcgt tgagttttga cactgtacaa cgtaaaaagc
    40261 agatatctgc ttttagctac cttatgaaaa gccttatctc gacaattcct gttctaccca
    40321 ttggcgtctc tcgacgtttt tgggcagtag cctatgtttg tataggagcc tcacctaaca
    40381 aatcctattc ggttttccct cgttaatata acaactaaaa aagaggatgt caaatcaatt
    40441 ttccatgttt ttcatacttt tttaaaatac acgcgttata tttcctgtct cacgcagttt
    40501 tatttgtctc attttccacc tcccgctata atagaattat agtaggaaac gaggtgctgt
    40561 tatggaacga acacttgtta ttatcaagcc agacggcgta agacgccatt tggtcggaag
    40621 catcatccaa cgttttgaag caaagggact ggccattgct gaaatgaaat ttgcaacgat
    40681 gacacctgaa ctagcaaaag aacattatca gcacttgact gaacgtagtt tttttgatga
    40741 gcttatcgat tacatgactt ctggtccggt cgtttatctt gtgctggtcg gcgaggaagt
    40801 gatcgatatc gtccgtaaga tggtcggagc aacaaaaggg gcggatgccg ttccaggtac
    40861 gatccgagga gattatgcac tgccggggac tgaaaacatc atccatgctt ctgattcccg
    40921 tgatgctgca acaaaagaga tcgcccgctt tttcccgcca ttcgatacaa acaaaccgtc
    40981 tgaaaaagcg gcgaagtgat acaaatccta aactgttggt ctaactgctg ggtttagcaa
    41041 tggccagcag ttttttctct aaagaattcc cttgattctt ccctaatgta tattcgatca
    41101 ctgcgaaaaa ctcttggtga ttttccgatt tttcttcccc taaagcagca gaaatcagtc
    41161 gttggtaata atccgccatc aatgtttcat aaatcactgt acttctttct ttatgcgcta
    41221 aactccgttt catatcttca ttcacgctac gtgccttttt taagcgacca ttttctatat
    41281 aaaacaaagt caagttcgtc aaaaaagtaa agagatactg ctcgtgatta ttcagttgcg
    41341 cgatccgtcg cattcttttt ttgattttca aataattatt ctcaataaaa cgatcactga
    41401 atatccaagg aaaatctgct agaatagata cttcaaattg cccatactct ggtacttgca
    41461 tcaaatattc ttcaatgata cgacattcat aacgcaaaaa ttcaaattcc gtctcagata
    41521 cttctgtttt tttggacatg tgcagattca aaaccaaata gtacagatct tctgttttct
    41581 tatagtgcct gcggttatta gcaatttctt tgtaaggatc aaagctgtct tcttgaatcc
    41641 gatctagcat tcgtcttttt ttctttaatt tttttggctc atcaagctga tttcgtatcc
    41701 attcatattc ggcaagtgtc atgttcattc gctctaaaaa tgatttcaat gttccaaacg
    41761 atactttttt cactgaattt gtctcgatcc cgactagcga agttttagaa cagattcctt
    41821 ccgctaattg ggtctgtgtc agctttttgt tgactcgaag cttcttaatc aattctccat
    41881 catacataat agttctcctt ttttaattga aattaaccct tggcttttcc agaatgcttg
    41941 ccaataagag gaatgattat ttcaatttaa attttccgca ttcaataaat agatacgtta
    42001 aaaataaaaa atacacgaaa aaaataaaaa aatgtttttc tcataaaaaa taccaacctt
    42061 caagcatgag actgctgtct aatccctgaa ggttggtttg attgtttatt gatcattttt
    42121 ttactgctcc gcattggttc ctgttactgg atataggata gtcgttgttt tattgccgtt
    42181 ttttgaaaag acactggtcg aatgttcacc tttttgcttt tcgattgctt cattacgttc
    42241 cgcttcgttt ttatagtcat attttttcgg atcaatcgtc tcaaatccgt ttggcacata
    42301 aaaccgcaag agattttcct gattcagctt atctgaaaga cttaacgcag tcttgacttt
    42361 ttcctgatct ttggagattt cctcgtcgat tcctgctgct ttcgtatcga tgatttctcc
    42421 tgtctgatta ttgtaagctt ttcctcctag gacggtgtat ttgggcgtca cgaagttccc
    42481 atttcgaaaa gcaactactt gatcgtgctg agaagataat aagtctgtac caaaatgaag
    42541 ataatcttta tcatcgattc ccaatagatg tagtaatgtc ggcaaaacat cgatttctcc
    42601 accatattca tgattgactg tccctttagt gtaaccaggc atatggatca tcaatggcac
    42661 tcgttgcatc tgtgcgttgt caaattcatc ccatgtatct ggatctttac caagagcact
    42721 tgctaaatct ttattatctg tattcgagat cccaaaatga tccccgtaaa tcacaaagat
    42781 tgaattttgg taaataccag attttttcaa atacgtaaaa aattgttcca atgattgatc
    42841 cagataatgg gccgttcgaa cataattatc tactgtgcta ttgccagtat tcaaagatgg
    42901 aaagtcgaaa ttcttgtcat ccgtataata aggcgtgtgg ttggttacgg aaagaaattt
    42961 cgtgtaaaac ggctgttgta gatgttcaag atattgggca gattctctga ataaatcttt
    43021 atctaatatc ccataaccta acgtttcatc ggattcatca aaataagatc gatcaaagaa
    43081 attgtcatac cctaaatttt tatatacatg atctctattc cagaaactag ctacattccc
    43141 atggaaaaca gcacttgtat agccttctgt ttgaccaagg gtcgctggtg ctgcttgaaa
    43201 gacattatct gacccaagtt ctgtgaataa tgagccttga ggtaaaccaa atgtgccagt
    43261 ttccaacatg ttttcagcat cacttgtctt tccctgtcct acttcatgaa agaaattgtc
    43321 aaaactgatc gttgcttgat tctggaaaat actatttaaa aacggcgtga cttcttgtcc
    43381 gtctaccttc atattgatca aaaactgttg aaaactttct aaatgaagga caatcacatt
    43441 ttttccttta gcaatcccaa atgtttcagg atttggctct gcataatgtt tctttgtata
    43501 gtctaaaact tcatcaattc cattactgct tgcatgcgcg cgaacactgc tagtcattcc
    43561 tgttttgatt ccgtcataaa tagtgtacgc atcgattcct agatatttga caatatagga
    43621 acggtcaaat gtccgctgta gcaattgggg acggttggct tcgctcaacg ctaaatttcc
    43681 tgaaaaaatc aatcctgaaa gacaggtaac agcgatagcc atcggtttgc tgacagggtt
    43741 gcttttgata ggtattttct tgaccttcaa ccaaaccagt agcccaatga acacagcgat
    43801 atccaaccaa tagatgacat catggggttt catcaaagaa aaggagcttc ctgacaaccc
    43861 ttgtgacact ttcgaaaagc ctaatacaga tttgactgta atgaaatctg tgaattcccg
    43921 ataaaaaata atattcaagt acaacaaaag cgtatttaaa atatcaatga tcaaaagaat
    43981 ggctaacgct ggctttggct ttttaatata caaagaaagg ccaaaaaaca ataaggtagt
    44041 cgcaatcggg ttgatccaca agataaagta ctggatcgta ccttccacac ctaatgaaaa
    44101 atctgcatag taggcaatga tcgtcttcag ccagaaaaag aaaacagctg tcaaaacgat
    44161 tgctaaacga ttttggcaca attttttaag ttgtgtcacg tatatcactt ctctctattc
    44221 acattttttc ttattttgct cctgaaaaat gaaaatttcc taaaaaagtt gttatcttaa
    44281 gattttttta ttctttctaa agattattcc attcattttt cacagcataa aatcgtttcg
    44341 gtgtaagcgg ttaaaatagt aaggagataa aaatcttgtg gtgaccgatt tactctatag
    44401 tattcaaaag tagtttctcg gtattcgtac aaaaaaaaca tactaagatt agaggggaac
    44461 atcattgacg aatgatgttc tcctctattt tctattttta gattatagtg aagagtgaaa
    44521 gaaagttcga acaaagcctt gaggactacg agtccctatc aaaaaccgaa cttctttact
    44581 gtcattttag aatcaggttt acgtatgttg gggccatgag cccgtgtata ggaaattgga
    44641 atcgaaatga agcagtaaag ttctttcaac acttaaaaag gaggaaaaca aatgccttac
    44701 attcttgcat tagatgtttc aatgggacac agctacagtg tcctatacaa agacgacacc
    44761 tgcttatttg aagacgagat cgaacacact caaagaggat ttcatgcatt actcgaagag
    44821 atccagcact tgcctgaacg tccattgatt gtttttgaag caacgggtat ttattccaga
    44881 ccagtcgaaa agttctttca agatcatcac ttttcttact gtttgttaaa cccgttagaa
    44941 gcgaaaaaac agatggaaga aaacacctta cgcagttgga aaacagataa atcggatgcc
    45001 catcggctcg cacagactca tcttaaaaat caacgtcaac caaaagaagt acaaagcaat
    45061 ttttacttag agatgcgcga tttagcccgt ttttatcaag aaattgagaa gaaaatcact
    45121 cgactgcgca tggatttaca caactgcctt cagttgactt ttccagagct tgaacagttc
    45181 ttttcaaaca ggctgacccc ttacgcattg acattgatcc gtctttttcc ccatccagat
    45241 tttgtattgg catctactcg gacaaaaata aaaaataaac tgatcaacga aacacgggaa
    45301 aaaatctccg cgaatcgtgc cgagcaaaag gcagatcaaa tcatccacta tgcacagtgt
    45361 gcctatccag ctgttgaaaa agacagtatt cactgtcaaa aaacgatcta ttacgccgaa
    45421 cttctccaag atttactcga acaaaaaaaa gcactggcga cacaaatgat caaaaaagcc
    45481 gaagcctctc cttgcttttt gttgtaccaa acgttccctg ggattggcgc actcacagcc
    45541 gctttattgc tcggtgaatt aggagatatc acacgattta aaacccataa acaattgaat
    45601 gcctttgtcg gaatcgacat ccgacggtat cattcaggta agtatactgg ccaagaccgc
    45661 atcaataagc gtggtaatcc caaagcacgg aaaattattt tcttcaccat tcgaaatatg
    45721 attcgccagc aacgcgcagc tcctaatcat attgtcgatt attactacaa attaaaaaag
    45781 caacctatcc ctaagaaaga taaggttgcc acagttgctt gtatgaacaa gcttctgaaa
    45841 tgtatgcacg ctatggttag ggcacataca gagtacgact atgcgtacgc ggtctcagtg
    45901 gaccattaac taaaccactt acagtatacc acttctttgc ccagatcgaa aattttttac
    45961 gaacggggct ttatttagtg tgccttgatt ttgtcgcttt cgtttacgag ctatttttct
    46021 tgcacctttt acttgactaa tcgtaggaaa gaggctgtga caaaattctt gtcgcagctc
    46081 cctatttctt gatgcaggac agctttttca caacctctcc a
//
LOCUS       DACGMI010000018        44605 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.018, whole genome shotgun sequence.
ACCESSION   DACGMI010000018 DACGMI010000000
VERSION     DACGMI010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.018"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(5..586)
                     /locus_tag="IXT46_001127"
     CDS             complement(5..586)
                     /locus_tag="IXT46_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4947054.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(769..1395)
                     /locus_tag="IXT46_001128"
     CDS             complement(769..1395)
                     /locus_tag="IXT46_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4947055.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(1417..2748)
                     /locus_tag="IXT46_001129"
     CDS             complement(1417..2748)
                     /locus_tag="IXT46_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAQ4947056.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(2903..3304)
                     /locus_tag="IXT46_001130"
     CDS             complement(2903..3304)
                     /locus_tag="IXT46_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAQ4947057.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(3390..3596)
                     /locus_tag="IXT46_001131"
     CDS             complement(3390..3596)
                     /locus_tag="IXT46_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947058.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(3691..5193)
                     /locus_tag="IXT46_001132"
     CDS             complement(3691..5193)
                     /locus_tag="IXT46_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAQ4947059.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(5211..5666)
                     /gene="argR"
                     /locus_tag="IXT46_001133"
     CDS             complement(5211..5666)
                     /gene="argR"
                     /locus_tag="IXT46_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAQ4947060.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(5764..6381)
                     /locus_tag="IXT46_001134"
     CDS             complement(5764..6381)
                     /locus_tag="IXT46_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947061.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            6602..7975
                     /locus_tag="IXT46_001135"
     CDS             6602..7975
                     /locus_tag="IXT46_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4947062.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            8050..9162
                     /locus_tag="IXT46_001136"
     CDS             8050..9162
                     /locus_tag="IXT46_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAQ4947063.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(9234..10871)
                     /locus_tag="IXT46_001137"
     CDS             complement(9234..10871)
                     /locus_tag="IXT46_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAQ4947064.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFEEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(11039..11647)
                     /locus_tag="IXT46_001138"
     CDS             complement(11039..11647)
                     /locus_tag="IXT46_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4947065.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(12031..13182)
                     /gene="queG"
                     /locus_tag="IXT46_001139"
     CDS             complement(12031..13182)
                     /gene="queG"
                     /locus_tag="IXT46_001139"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAQ4947066.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(13201..13953)
                     /locus_tag="IXT46_001140"
     CDS             complement(13201..13953)
                     /locus_tag="IXT46_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947067.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(14094..15044)
                     /locus_tag="IXT46_001141"
     CDS             complement(14094..15044)
                     /locus_tag="IXT46_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAQ4947068.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(15045..15884)
                     /locus_tag="IXT46_001142"
     CDS             complement(15045..15884)
                     /locus_tag="IXT46_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAQ4947069.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(15881..16627)
                     /locus_tag="IXT46_001143"
     CDS             complement(15881..16627)
                     /locus_tag="IXT46_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947070.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            16865..18235
                     /locus_tag="IXT46_001144"
     CDS             16865..18235
                     /locus_tag="IXT46_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4947071.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(18290..19186)
                     /locus_tag="IXT46_001145"
     CDS             complement(18290..19186)
                     /locus_tag="IXT46_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4947072.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(19467..20144)
                     /locus_tag="IXT46_001146"
     CDS             complement(19467..20144)
                     /locus_tag="IXT46_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAQ4947073.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(20235..21140)
                     /locus_tag="IXT46_001147"
     CDS             complement(20235..21140)
                     /locus_tag="IXT46_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4947074.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTGESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            21315..22769
                     /locus_tag="IXT46_001148"
     CDS             21315..22769
                     /locus_tag="IXT46_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4947075.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPTLSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVASASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            22785..23816
                     /locus_tag="IXT46_001149"
     CDS             22785..23816
                     /locus_tag="IXT46_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAQ4947076.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            23823..25010
                     /locus_tag="IXT46_001150"
     CDS             23823..25010
                     /locus_tag="IXT46_001150"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAQ4947077.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            25166..26548
                     /locus_tag="IXT46_001151"
     CDS             25166..26548
                     /locus_tag="IXT46_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAQ4947078.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            26520..26906
                     /locus_tag="IXT46_001152"
     CDS             26520..26906
                     /locus_tag="IXT46_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947079.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(27106..27774)
                     /locus_tag="IXT46_001153"
     CDS             complement(27106..27774)
                     /locus_tag="IXT46_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAQ4947080.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(27963..28760)
                     /locus_tag="IXT46_001154"
                     /pseudo
     CDS             complement(27963..28760)
                     /locus_tag="IXT46_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(29041..30420)
                     /locus_tag="IXT46_001155"
     CDS             complement(29041..30420)
                     /locus_tag="IXT46_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4947081.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(30595..31764)
                     /locus_tag="IXT46_001156"
     CDS             complement(30595..31764)
                     /locus_tag="IXT46_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4947082.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(31739..32890)
                     /locus_tag="IXT46_001157"
     CDS             complement(31739..32890)
                     /locus_tag="IXT46_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAQ4947083.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(32850..34211)
                     /locus_tag="IXT46_001158"
     CDS             complement(32850..34211)
                     /locus_tag="IXT46_001158"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAQ4947084.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(34208..35209)
                     /locus_tag="IXT46_001159"
     CDS             complement(34208..35209)
                     /locus_tag="IXT46_001159"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAQ4947085.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(35225..35920)
                     /gene="dapD"
                     /locus_tag="IXT46_001160"
     CDS             complement(35225..35920)
                     /gene="dapD"
                     /locus_tag="IXT46_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAQ4947086.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(35926..36642)
                     /locus_tag="IXT46_001161"
     CDS             complement(35926..36642)
                     /locus_tag="IXT46_001161"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAQ4947087.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(36639..37520)
                     /locus_tag="IXT46_001162"
     CDS             complement(36639..37520)
                     /locus_tag="IXT46_001162"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAQ4947088.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(37523..38323)
                     /gene="dapF"
                     /locus_tag="IXT46_001163"
     CDS             complement(37523..38323)
                     /gene="dapF"
                     /locus_tag="IXT46_001163"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAQ4947089.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(38310..39569)
                     /gene="lysA"
                     /locus_tag="IXT46_001164"
     CDS             complement(38310..39569)
                     /gene="lysA"
                     /locus_tag="IXT46_001164"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAQ4947090.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            complement(40055..40618)
                     /gene="efp"
                     /locus_tag="IXT46_001165"
     CDS             complement(40055..40618)
                     /gene="efp"
                     /locus_tag="IXT46_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAQ4947091.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            41046..41963
                     /locus_tag="IXT46_001166"
     CDS             41046..41963
                     /locus_tag="IXT46_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAQ4947092.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            41976..43121
                     /locus_tag="IXT46_001167"
     CDS             41976..43121
                     /locus_tag="IXT46_001167"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAQ4947093.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            43292..43750
                     /locus_tag="IXT46_001168"
     CDS             43292..43750
                     /locus_tag="IXT46_001168"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAQ4947094.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            43909..44379
                     /locus_tag="IXT46_001169"
     CDS             43909..44379
                     /locus_tag="IXT46_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAQ4947095.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(44432..44547)
                     /gene="rrf"
                     /locus_tag="IXT46_001170"
     rRNA            complement(44432..44547)
                     /gene="rrf"
                     /locus_tag="IXT46_001170"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        12495 a         9258 c         8080 g        14772 t
ORIGIN      
        1 attattaaag aaccttttgc gaagttaaca atctttcttt gatcaattga aaattctgcc
       61 taagtagtga tagatcctgt gtgactttca acaataagat acttccctgg atttcagcaa
      121 tcaacgcttt ggcttgacgg tctgcttctt catcggacag tttttcttca gaaagtgcca
      181 ggatattttg tttcgtatac ttgacccatt gattgactaa ttctagtagc aacagacggt
      241 attcttcatc cactgtactc aactcaataa tcaaattacc tacaggacag ccatgataag
      301 tgatctgtgt ctcatgatca gcgaaaatcc agtccaacat ttcttctaat gcttcttctg
      361 gctgttttcc agcatttaag atgtcttcga acaattctgt ctgccatacg tccatatgcg
      421 catggatcac cgctagacaa acttcttttt ttgaagaaaa gtaataataa aattgacctt
      481 ttcctgtatc agaagctgct agaatatctc ggattgacgt ttcatgatag ccttttttat
      541 aaataagatc tttggtcgct tccaagatct tttcctttgt tttcaatgat attctccttt
      601 ttcatttctc atagtcctat attatacagt aaattcatca ttttttcttc ttaatcgttt
      661 aaaaaagact gtgccaaatt atctgacaca gccctcacta taaaactgtt ctcatatagc
      721 tagatgttca ttgattcaag aactgcgagg acaaaagcaa ttcctatctt atgatagttg
      781 ctctaatact tcctctgttg tcatcacttg atctgcaata aagccaaagt tcgtcaacgc
      841 tgcatccatt gcttcttggc caggagcacc aattgcatct gtcgctacca caacattgaa
      901 tccactctct accaattcac gcatatggga atcgctacac aagtttccgt tcattccacc
      961 aagaattact gtgtcgattc cattttttct caattggagc gccaaatcat tgctttctgg
     1021 tccaaagatt ttatgaggag agctgatgat cgtattttca tccaaataag gtttcaattc
     1081 ttcgataaaa tcggctcctg aaccttcttc cactgattca tattgacttt ttctagcaaa
     1141 catctgctgc tcaagcatca tatgttctcc tgcaccgcca aattgccatt tatggtcatg
     1201 tgggtaaaaa taatgaggag aaataaagag tttgtatcct ttttcttttg cttgttttac
     1261 catttcaatc atattttcga tcgtattgta tttttctaag atatcttttg tcaaaccaaa
     1321 gccaccgcct gctggtttca agaactcgac ttgcgggtca gtgagaacta ctgctgtatt
     1381 tttattattg aacatggtgg attctccatt cgttatttat tttaatacat catttagagc
     1441 ttcactcatt gtcggatgag aatagatttg atctctcaat aacgtataag gaagttttcc
     1501 attcatagct agcgaaatca agttgatgac ttcatgagaa tcttccgcat agatacttgc
     1561 ccctagaatc aagtcagttt cagggtcgac taaaactttg aatacacctt taggatcttc
     1621 taatacttgt gctttaggga caccgcttgt catatacttg aataatttgt aattgacgcc
     1681 ttgtgctttg gcttgttttt ctgttaaacc tacattggat aaagtcggag tgataaatac
     1741 actgtaaggc acagctttcc ggttattcgt tgttcgttta ttctcgccct tcaactgatc
     1801 cataatgatt cgataatcat ctagagagat ataagtgaac tgcaatccgc ctttgacgtc
     1861 tccaatcgcc caaatgttgt ctgcatctgt acgaaggtat tcatccacag cgattgctcc
     1921 gcgatctgtt agtttaacat ctgtattttc taatccaagt gatgctgtac ttggttttct
     1981 tccagttgca gccaaaactt ttgacgcttg gattgttact tcttggccat cttctgtaaa
     2041 ggtgacggca gctgttgatt cttggtctgc tacttgatct acagatacac ctagatggaa
     2101 ttcgattccc gcatttgtca tgtcttctaa aatcatttgc gcgatatctt catcttcacg
     2161 tggaagaaat tcagaatggg catcaagaac gacaacttta gatccgtatt cattgaacat
     2221 tgatgcaaat tccaagccaa tatatccagc cccgatgatc actaattttt ccggtaattg
     2281 ttcctgatcc atcgcttgcg tagaatcaat caagtagcga cttgtattca atcctttgat
     2341 tggtaaaatg attggttcag aaccagtatt gatgaaaatc cgttcgcctt caacaatcac
     2401 tttttcacca ttattcgtca cttcgatttg atggttagaa agaaaacgtg ctgtaccgtc
     2461 catcactgtc ccagttgcct catcgctgat catatgataa tttttggcgc gaagcatgcc
     2521 cgtcaatttt tctttccgag caacagcctc tgtaaagtcg attcctcttt ctccattgaa
     2581 aatcaatgat ttagaaggaa tacagccgat gttgatacat gttccgccat acatacgtgt
     2641 tgacttttca acgactaaaa ccgattcacc ttttgaagct aacgccttcg ctaaagtctt
     2701 accgcccttt ccaaaaccga tcacaatatt ttgatatttt tccatcattt ttccctcgct
     2761 tcttttttac ctaccgattg gtacaaaaat atgataaccg ataattgtct attctccaaa
     2821 tcatctgctt tatttgtcaa aaaaaaccag acaaaaagcg gtcctttcac gtttttagtc
     2881 tggttcgatt tcctttattc ttctaaacaa tcgttacttc tacatcgata tttcctctag
     2941 ttgctttgga gtaagggcag aattcatgcg catcttctgc aattttttgg gcttcttctt
     3001 cgctgatgcc atcgatatgc acttctaata ctacaccgat ctgatagccg ccatcatcta
     3061 aattataaag agagacacgt gcttttactg tggactctgc tgtcattcct gcttctttga
     3121 tcatatgttg taccgcccca ttgaaacaag aagcataacc tgctgcaaat aattgttctg
     3181 gatttgttcc ttctgcatgg attcctggag gagtgatttt catatgcatc gagccatttg
     3241 gtgcctcgac ttctccattg cgcccgccat ggttgatcat tgctgtttcg tatgcttttt
     3301 tcattgtact gctcctttcg attgaccatt tgctacttgg ctataattat agtgtatgac
     3361 aagtaaggcg ctttctacaa aaattctgct tattcgaata ccagaatgcc gtcttctact
     3421 atttttccaa aaaacaaaaa aatactactc gtgaacaaca gcgtcatatt tgttccaaaa
     3481 taaatagcaa tcttttctac ataatctttt atatgattga ttttaagata catatatacc
     3541 agaaagttga ccccataaac caatactgtt aaaaaaataa ccatattcgt taccattttt
     3601 tcctcctttt gctggtctcc ctaccagcac tcgatttaac cataccactt tttttgccgt
     3661 ccaagcaact agcctttcaa aaagactggt ttattctgct gttaatgatt caagatcaga
     3721 aaaatgtccg aataattttg ctaattttac taacgccaac ttgttctttc cgaattcatc
     3781 attttctatc tgtaatacta gtaacggctc atgtaagctt aaacggatca aaaaccagcc
     3841 gtttccgtat ggctcttcta gatcatatcg aataccttct tcattttccg ggtcgaagtt
     3901 catccctttt tcttcttcca acagtcgctt catttcttct aatatcttgt ttccttgttc
     3961 gcgtggttca tcgctgaaca attttaatcg gatttcttgt acttctacgg gctgtttcaa
     4021 ctctttgatt tgttcatcta atgtgatacc ttttcttttt aattctggca aaagcatcag
     4081 gatctttgcg atgacatatg caccatcatc cagaaaatag ttttccttga atgcagcgtg
     4141 tccgcttgtt tcgatggcta gctgtgtatc tttcccaaga cggttaagtt ctaatgcttt
     4201 attgattaca tttcgatagc cggaaatata acgaacttgg atgcctcctt tttcttcaat
     4261 gaatctttgt agatgagaag aagtagggga attcgtcacg attcttgttc ctggatgctc
     4321 ttttaatacg attgtactta atactgcgat caaattattt cgattgatca ctgttccaga
     4381 agcactgaca actgcagaac gatccacatc tgtatcgaaa atgatcccaa gatctgcttc
     4441 atttgctaaa acagcctgct tgatactttc catcgcttct ttattatcag gatttgggat
     4501 atgattagga aatcggccat ctggttccaa aaattgggaa cctgttgaat ccgcacctaa
     4561 gctattcaat actttttcag caaagaatcc accagcacca tttccggcat caacaatgat
     4621 tttccaacca tttagtggtt tgctttctag tgttccaatc ccctttttaa tttttgtgac
     4681 taaatcttgc gcataaggtg tcaaaaggtc tgctttttct acgcttccag tttgttcgct
     4741 ttttattttt tgctgctgtg ataggataaa agcaatatct tctttttctg ctcctccttc
     4801 tgaggtaaag aattttattc cattataata atagggaaga tggctagcag tcagcataac
     4861 cgcagcatcg cacgagaact gttcaaattg agtggacata aacatagcag gcgtagtagc
     4921 taattcgaaa tcgatgacat gtatcccttg ttctttcaga ctttggatca acgcctcttt
     4981 cagtgctggt ccgcttatcc tactgtcatg accaatccca atcgtccatt ttttatttgg
     5041 atcggttgat ttcttctttt tctttatcca gtttgctagt ccccagccga tcttttttac
     5101 catgtctgtc gtcaagttta cttcatatcc ttcaactggt aatgcgattc ctcgaatatc
     5161 cgatccattt tgcagcgctt tcatatcttt catataaaag tcctcctcat ttattccctc
     5221 attttttcca gcttttctgc aaatcgctgt gcttcttctt ctgagcggca aataataatg
     5281 aatgtatcta caccggccat cgttccgaca acttcagggt aagccacttc atctagccaa
     5341 ttcgttacca catcggcacc atttcgttca gtcaatacga taaccatgaa ctgaacagac
     5401 tggatacgca aaacctcgcg tctaattgct gtacgcaaac gttcttcatt taaagaaaca
     5461 gatggctggt taaataatgt atagcgtact attttgtttt cattttgact ttttactaac
     5521 ttcatttctc gaatgtctcg agaaatcgtt gcttgagtca catcggcgcc tgcttcatgc
     5581 agccgcgcaa gcagctcttc ctgtgtccca ataggttgtt ctgtaatgat ctggcggatc
     5641 agtgcttgtc gctgtttctt tttcatatta gacacctctc aatgttgatt atagcaaaag
     5701 ataagtaata tttcttcata ttttggtatt ttttactttt attttttgtt ttcattcagg
     5761 ttgctaacct ttttctattt taacacgcaa aatcgtcttc attttttcag gtgctgattt
     5821 tcttggatcg ctgatgtaaa tctctttgtg ttctttagaa gctctttcat agccttcttt
     5881 tgcgatgaat gcttctaatt tctcaaacgt tgctggttct tcggcatagg gcccgacgtg
     5941 taagatttgg gcacaaagac cttcttccat ctttttgaat actacttgtt ctttcaagtc
     6001 ttccggaagt ttgctagaac gctgaatggc ttcttgtgct atcgcttctg taacaaagtc
     6061 aggctgtcgg atcatcaatt gataagaaaa atgttctttt ttcatcactg gttcatgcaa
     6121 atacttttct tgcagtcccc attgtccttc cagtggatag acagtataca tctgataatc
     6181 aggaatcagc caattttttt taggcgacat gcgtattgca tagctgactg catatagaca
     6241 ggctactctt cgtttaaagt cttcctgatt cgggtcgccg atccctctga tgctaaagaa
     6301 tgatttttta ggaacctcta gtatttgcgg gctttttttc atactatagc tcttgtcttt
     6361 acgccattca attttttcca tttttcttcc tccgcgaaat tccatttagt tatttattat
     6421 catacctctt tttgagtgac ttggctaatc gtgttgacac tatttttcag tttgtgctag
     6481 aataagtgaa gtaaataaat cgtacagata acacgtttcg gcgtgtcgag agagaggcgg
     6541 tttctatttt tataatagaa atcactctct ttttttacga aattttttag aggtgatgta
     6601 aatgacaaaa caaaaacagc tgcttttagt acctgcagta attgcaacag ggatgatgtc
     6661 ttttgcgggc gtattgatcg agacggccat gaatgtaact ttcccaactc ttatcagaca
     6721 gtttgattta acgactgcac aagtccaatg ggtaacaacg atttatcttt tgatgatttc
     6781 gatcattgtt ccgctgtcta cttatttgaa tcgcaatttt agtctcaaaa aactcttttt
     6841 agcttcaaat ctgcttttct tggcaggtat aatgatcgat ttcttctctc ctaccttcat
     6901 ggtcctattg tttggtcgat tgctccaagg tgcagcgaca ggtatcgctc ttccgttgat
     6961 gttccatatt atcttgacat ttgcccccct caatcgacga ggcgcgatga tgggtgtcgg
     7021 tactttgaca acggccattg ctccagcaat tggccccact tatggaggca ttatgacttc
     7081 acattttaca tggaatcata tcttcctgtt tcttgtgccc gttttgattc tttctttgat
     7141 tatcggctgg tttgctattc ccgagatggc agtacaaaaa agtggttatt tggattggat
     7201 aagcgtttta ggaatttgtc ttttgtttag tggaagtcta acatttttga gtacgttggg
     7261 aacagtttcc agctggattg ctttaatcat cggcggtatt ggctggttcc ttttttacta
     7321 tcgaagtaaa aaagtggagc atccactgat ccgactgtct attctttcaa ataaaacatt
     7381 ccgcttgttt ttgattggct tcttagttta tcagttttta ttacttggtg tatcttttgt
     7441 cttgccgaat ttccttcaga tcgttcaagg aagtagtcct tttgtcgctg gattagcgat
     7501 gcttcccggc gcagcggttg gtgctttgct ttctcctttt tccgggaaaa tgctggatca
     7561 atatggtccg aagaagccaa tttttgctgg gctgattctt tctttgattg gttggctagc
     7621 attattccta ctcataggac acgcttcagt gggtgtattg attgcttgtc atgtgtttta
     7681 tatgatcggt atcggattat cttacagcaa tatgatgacc accggaatga atgcactgaa
     7741 tgaagaacta caaggagacg ggaacgcaat gttcaatacc ttgcagcagt tttctggcgc
     7801 tgtggctact tcattagtag cggtcattat caattacgtc cagcatcata cttcccataa
     7861 ctatgaagtg tctactacat taggatcaaa agcagcatta ggcgtcttgt tgctgttgct
     7921 tctcgtaagc tttgctcgat tcgcctatta tctgttcttt gctaaaaaag cgtagattcc
     7981 atatacggca ggtgttgcat ctgccgtttt tttgtgtgaa aatggttgtt tgtaaaagga
     8041 ggctttttta tggaaaaaat tgccattatc ggtggcggga tcattggtat gaccctagcc
     8101 agttacttag atacatcaaa attcaatgtt gctttatttg atgaagggac aggacaggca
     8161 actaaagcta gcgctgggat tatctcccct tggttgtcga aacgcagaaa caaacaatgg
     8221 tatcgtctgg ctaaagacgg cgctgctttt ttccctaaac ttataaaaga tttccaactt
     8281 gatcaaacga tttacgcaca atcagggaca cttttgcttc gacctgaaaa agatttagct
     8341 gaattggctg ttcttgccga gaaacgaaaa gaagaagcgc cagaaattgg aaacatcgaa
     8401 tggctttcac ctgaacagac atctcaagca cttccgttat tgaaaccagc agtttcactg
     8461 cgtatcagtg gtggtggtcg tctggatgga aaagcatatt tagaacatct tggtcagcgt
     8521 ttagcacaaa aacaaatgga gcagatccag gcaaaagtca ctttgcataa gaagagcgat
     8581 tcttggctca tcaagggacc gtttggagaa tacacagctg atcgtgtaat tttgacacct
     8641 ggcccggcac ttaagccttt attacaagaa ttaggctatg ctgcagatat acgtccgcaa
     8701 aaagggcagc tcttagcatt tcagacatct tataagatga gtcaagactg gcctgttgct
     8761 atgcttgacg gagaagctga tttcattcct ttcatggatg gaaagatcct tttaggtgct
     8821 acccatgaaa acgatcaagg ctgggatttg gctcctacta gcgaagctta taagggattg
     8881 actaagagta cagaacagtt cttgactgat ccagatcaga taaaaaactg gccatacgag
     8941 ttccgtgtag gtacccgtgc ttatacgtca gatttttccc catttttcgg cgtactgcca
     9001 gatgatccaa gcttactggc tgctagcggt ctaggctctt ctggcttgac cacaggtcct
     9061 tatatcggct atctattagc caacttctta aatactggtc attggcctac ggaagattat
     9121 caaaaggaca tctccaccta tattacgaaa aatccatcat agaaaaacag ctttttcaag
     9181 taaggatccc gagcgatatt gcgcatggat tacttcttga aaaagctgtt attttagttc
     9241 aatttctgaa tcaaattctc caaactttct tttgcttcat ctggcaagag atcttttcct
     9301 atctgagctt caatgaatcg taaacgaata tcaagtcgtt gtttcaccag atttttatag
     9361 gacgtatcct caaaagaaac aggaaaatct ggtataggta aatagtggat gtcttcaaat
     9421 ggaccaaacg acttgaattc tgccgtttgt tgcacgattc tttcaacgat tgacaatgtc
     9481 gtttcaggtt tgattttttt atcatcgaaa tatccagtat tcaggacata gcaggctgtt
     9541 tgctgtttca aaaacaactc tcgaaaagct tgatagtctt ccctaagagg atagacacgg
     9601 aaaggattag caaatggttc aatgactagc tcatctagct gtctttttgt agtgatattt
     9661 tccgcgtctg atcgttttgt tgctaatgtt gcaccaaaag acgctgctaa aactgggtca
     9721 ttgatcttga taattggcgg aagcgaatca tctttcatga tccaaaaaac agcatcgatc
     9781 ttttcgctaa gatgatcgac tcggtcgggt gtcgcataac gtgatttgac tgtccgccca
     9841 tttccgtttc gtatatctcc tgttactagg actttttctc ctttacttgt acatgtcacg
     9901 cccacattct gacaagtaag gaaagaagaa atggccggat catcagacgg atagtcttgt
     9961 gttttatcaa agtaagaagg ttccaaggca gtagcaaaac cattttttcg agaaataacg
    10021 aaagcatcgt catgcaagat cgaaacagag tgaccttccg tatgttttgc taaggtaatc
    10081 gttgattttc cagaaccgga caacccaaat acagccatcg tataggtctg gtcattacta
    10141 gcatattgtt tcatcccacc gtggcaggca ataaagccat tgcgatttcc caatgcccaa
    10201 gcaagcgtca aagtcgcttt ttttaattct ccaaagtaac gtaatcctag cacagccgct
    10261 gtattatgga gagcatcaaa caaaatgagt ccatttggaa atgtttcatg tgtccattcg
    10321 ggatcacaaa agatataaag atctccctct tcaaaggaaa cagacttttg ataagtctct
    10381 aagatcttcg aattcgctgg ctgaaaattc agcaaataag aatacaaatt gttctcaaat
    10441 ccttctggaa tcagcaaatg actttgcaca gaaaattctt cagataggcc aacgattact
    10501 tttgtatggt aaaactggcg cttgcgactt tgatacacag cttctcttaa aattttctcg
    10561 tatttgcttt gttccttgtc taagtcctca aagatccgcc gagcacttgc tgttcttccc
    10621 acaatgcttc catcattgaa tactagtgtc ctaacatcag ctggtaaatc tagttcttca
    10681 gcatgtgaga ttgttaaatc tgtgatgatc gttcctggac tcccttttgc tagttgataa
    10741 gctgtcttcc tatcaaaaac ttcatgaaca ttattaccgt aaaatgtcgt ttctacaatc
    10801 gatcgaatac tggataacag tggatttcca cttgtgattt cgtttaattc gagactctct
    10861 tttgtactca tggctcctcc tcattcccta aacaaaaaaa cgttttcttt attatacatt
    10921 attcgagttt ttatttgtac tgctgcgctg tgggaagcaa acgagttatt tttcacacaa
    10981 aaaaaccgag aacttgaata aacaagtttc tcggtttcat cattttcctt ttatcggctt
    11041 agtaccagcc gtttgctaac cagaatgttt tagcagcatc ccatgaacca taacgagatg
    11101 ttacatattg ttctgctaca cgttcttgat tggcagctga atagtcgccg tttaagtatg
    11161 aagcatctaa ttgataacgg ccgatgtaac gtccgttagt agctgtgtat gaaccgcctg
    11221 attctttttg tgcgatccat tcttttgcag agcttgaagt tggcgctgtt gcagcagctg
    11281 gggcagcagg agctacttca actgtttcaa caggtgcaac gtatgtatgt tcttgcgttg
    11341 ctgtttcagt tgtagatgct gtattttctg ttgttttgtt ttctgttgtt gctgaagaat
    11401 catttgaagt tgggattgtt aattgttcac caacataaat gcggttgatg tttgcgatcg
    11461 aatttttttc agcaattgca tcgatcattg agttgtctcc tgcaaatttt tgtgagatct
    11521 tagataatga atcacctgat tttactgtat aaacttcatc agcgtgagca tttgtagttc
    11581 ctacaaacat tgcagtagca ccagcagcaa aagttgtacc taaaacaatt ttcttaaatg
    11641 aattcatatt aaactccttt ttttctccgt tttttattct ttcgacgcta ttaactttat
    11701 catttagaaa tatttcatag gtaaaagaaa catgacattt aatgacaaaa taacgaatta
    11761 tttaatattt gtaacattta aacaaatatt tttttgatac aaaaccataa aagccttgtt
    11821 gtataagcaa agtaatcgtt tttctatgtt tttttatttt tgaatgaaaa acgcagattc
    11881 tgtaacattc actgcaataa tccataaaaa aaagcaaaaa aatttttgat ttttatcaaa
    11941 ttctcttaaa aaaatgtaaa aaatacaaaa aaaccagtaa ttgttacaac aattactgga
    12001 caaaaacttt gaataatgtt aactattttt ttattttaac tttctccgca ataatttctg
    12061 ggcatgttcc aattcgttta taacgacttc ttctgtttct ttagctaata tttcatctaa
    12121 tacatcaagc catttttccg gttcttttgt tcctagacgt ccaatagccc aagctgctgt
    12181 tcctctgatg acagggcgga catctgttaa acattctgaa atctcaggca atgccgttcg
    12241 atcacctaga ttagctaaag caatcaatgc gtttctctgc aaaggtttct tcccacgcca
    12301 tgaaccagct aaatgcccaa attgctgttt gaagtcttta ttagacatcg aaagcattgg
    12361 ctttaatttt ggatatattt cgtctacttt tggttccatc tcttcatgaa aatgaaaatc
    12421 ttttccttga ttgtaagggc agactaactg gcagatatca catccataaa tgacatttcg
    12481 cattttttta cgatattctt ccggcatcat cccttttgtc tgagtttgat aagacaaaca
    12541 tcgctgggca ttcattcttc cgtcaccaag caatgctttt gtcggacaag cagtcacgca
    12601 gcgcatacag tcaccgcaac caaattctcc tggtttatca ggctcaaata caatattagt
    12661 aacgatctca ccaagataga caaatgaacc gaactcttca gtgatcaaca atccgtttcg
    12721 tccaataaat cctaaaccag ctcgctgtgc tacagcgaca tcgatcagtt ctccagtatc
    12781 tacttgcgga gctagacgcc attcctcttc tttttgccat ttttctgctc ttgtttggat
    12841 gaattcgatc aatcggttca aacggtctct gagtatatca tggtaatcga tcccccaaga
    12901 agcacgagca aactgcccgc gtttttcatc cctaggcact tcttcatgga tcctagtagg
    12961 atacgcaagt gcaatggaaa tgatcgattt cggctgatca aatgtcattt ctggataaag
    13021 acgctcatcg atatttggat gttcaaagcc agaagtatgg ccagctgctt tttgttcttc
    13081 caacgattct tttaatgaat caaaaggttc cgccgtggtg aacccgattt tgtcaattcc
    13141 taatcgtttg ctttcttgta tgatttcttc ttttaatgtc atggtcttcc tcgcttgctg
    13201 ttaacggctg tataacccat aatatagttt ttcttttttc agctggacaa actggatctg
    13261 ctgatcggca atcttctttt cttccatcca tttttttctt gcagcaaata cttcccaata
    13321 atttgttgaa attaattttc ttttgttatc taatgcatta aaaaaattca atgaaactgg
    13381 ttttgtactt aacagttcat ggagccttac ctcttcccat ggcgaaaact cagacagatc
    13441 gcgggaatac aatacttctt catagagatt tttttgctgt gtgtacgtga atgtttgcgg
    13501 gattttccca ggcctagcaa tttctactag acgattataa aacatattca ttaatttgct
    13561 gttggcaata aattgacttt tataataggc cgactggatc tttttgatta ctccttctgc
    13621 tttgatgact gaaaataatg caggccatgc tttgacggtt atttcgtcgt tttgtttaac
    13681 taatacgcca ggtgtgaagc cgactggaga aaggaacaca aaataaccga taccggtatt
    13741 ttcatctaaa ggctgaaatt catcaaacaa ccatttgcct atgtacagct cttcatctgg
    13801 ttctgttgtc tcattttgat ttgctatgaa taatttagct aattctgctt caagaaattg
    13861 aaggtcttga tccttgtcgg tattttcctg ctggctgatc aatcgaaaga cttcttcttt
    13921 aatcgtatat ttatctttac gtgtaaaatt catagccaca ccttccttcc ttactctaac
    13981 tataacggaa tttcttcaaa aaaggtatct gtacgacgaa aaacagcata attttttttc
    14041 atatctctta taaaaaatgc aaggtctgct cctcaagcta gaccttgcac ttttcagctt
    14101 tcttttgttt gtgacaaacc ttcatggatc gtttcaatat tccatttcat catctgatag
    14161 taagaatctc cttgttctcc ttcttttgct atggaatcag tgaacagttt atcatagatt
    14221 ttcaaacccg tttcttttgc tacccgttcc atgcttcttg agtctacact ggtttccacg
    14281 aataaaaccg gtacttcttt tgctcttatc tgatcaatga tcgctttcat ttgatcaggc
    14341 gtaccttgac tttctgtatt gatctcccat atataagctg ctggcaaatc atatgctcgt
    14401 gaaaaatact tgaatgcccc ttcacttgtt actaataatt ttttgttctc ttcgatagaa
    14461 gcaaaacttt ccttcgcttg tgtatctaat tcttttagtt tttccacata tgcttctgca
    14521 ttttttttat agagtgtcgc attttctgca tctttttcag agaatatacg tgcgatttcc
    14581 tccacatatt ttattccgtt agataggtct agccaagcat ggggatctgc ttttgtatgt
    14641 tcttcaccgc tagttaaata aagaggttct acatttttgc taactgcaaa ataatctttt
    14701 ccttcttctt ttttagccgt ttccatcaag ttatcgaacc agctgttacc tgtttcaaga
    14761 ttcaaaccgt tgtataaaat aacatctgca tcgcttgcct ttttgatgtc ttctggtagt
    14821 acttcatatt catgcggatc tgttccgact ggtacgatac tgtggatatc tatttgatct
    14881 gttccgacct cttttgccat gtccgccaag atcgaattgg tagccacgac tgacaacttt
    14941 tctttacttc cttcatccgc ttggtcagaa gcctgctttc cgcaaccggc taataccaag
    15001 aaactaactg ccaagattaa aaagagtgat ttttttgttt tcatctatct gcttcctttc
    15061 tgaaataaaa ttccttttgt tggagaaaat aaaaaagcaa ggataaaaaa tgcggtacat
    15121 gctaacacga tcgtagctcc tgatggccaa ttgtaactat aactgaaaaa cacaccgaca
    15181 actgcactta gcataccgat tcctgcagct gtaatgatca ttttcagtaa atggttcgtt
    15241 agcaagtaag ccgtggcggc tggtgtgatc aacatggcaa tcaccaagat tgttcctact
    15301 gtctgtaaac tgactacagc cactaatgtc aaaaagaaca tcaaaagata atggatcagc
    15361 gatgtgttca gcccataagc ttttgccatt gtcggatcga atgatgtgat cttcaattct
    15421 ttataaaaga aaaagacaaa tatcaagacg attccactaa cgagtgctgt cagcaacaaa
    15481 tcgctttccc taacagctaa gacattccca aataaaatat gatacaaatc tgtcgcactc
    15541 tgggcatatg aaatcaagat aatccctaat gcaaaaaagg agctaaagac aattccaatc
    15601 gctgtatcat ttttcaatcg gctccgctga gtcacgaaac caatcactgc tgctgttagc
    15661 atcccaaaag cagtggctcc aaagatgtaa ctaaaaccaa acatataaga aatggctaca
    15721 cctggaagaa ctgcgtgaga gatagcgtct cccatcaaag acatccctcg taaaataata
    15781 aaagaaccga tgactccaga agcaagtcct acaagcatgg aagtgaccaa agcgtattgc
    15841 aggaattgat aattcattaa tccatcaata aaggattgga tcattttttc tctcctcctt
    15901 ttactaaatg tctgatgatc tcaccatagg ccaattgaag gttcttcgat gtaaagactt
    15961 cttgtactgg accggaagcg atcagctgtt tatttaaaag aataacctca tcgaaatatt
    16021 cttctacttt atgaagatca tgatggacga tcaaaatcgt ttttcctgaa ttcttcaatt
    16081 cctgcaagat gtcaaagatc tttcgttcac ttaacgcatc aatccctacg aatggttcat
    16141 ctaaaaagat ccattctgct ccttgggcta gagctcttgc aataaaaact ctctgaagct
    16201 gtccacccga tagttcgctg atctgtcttt tggcatattc ttccatccct acttttttca
    16261 aagcttgtct tgcacgttct ttttcttttt tcccaggtct ttgtccaatt cgtaaagatg
    16321 gatatgttcc taaaagtaca acgcctaata catcaattgg aaaggaaaga tccaattcac
    16381 ttcgctgttc cacgtaggct atttttttac ggactgagtt taccgactgt ccagaaaagg
    16441 tgactttacc agtagtagct ggtatcaact ctagcaaaga tttcataaat gttgattttc
    16501 ctgcaccgtt tggtccgata ataccggtaa ttttttgtgg atttatcgtc aagttgatag
    16561 ttttcaaaac agttttccct tgataagcgg ctgaaaggtc ttgaattaca atggccgtac
    16621 gttccaaatc ttacactcct ttttaggttt acctaacttt ttatttaaat atagtttaac
    16681 taaaatggaa agcattttca agtagaatga tgaaaaagtt tttttcgaat tttcctcgca
    16741 ttttatgaaa attttctgta gaatcacatc aagagttcaa taaggctaac ctaataatga
    16801 aaaacatgtg ttgaaacgtt tgattatttt ttcttgttga ctcaacaacg aaaggagttt
    16861 ttgtatggaa gaagaaaagt taactcgaag tcttagtgcc cgtcatatcc aaatgatcgc
    16921 actaggtgga acgatcggtg tcggtctgtt tatgggtgcc tcctcaacca tacgttggac
    16981 agggccctca gtgatgggag cctatgcgat tgcaggattc tttttgtatt tgattatgcg
    17041 tgctttaggc gaaatgcttt acgttgatcc ttcgactggt tcttttgcaa attacgcgag
    17101 cgagtacatc catcctgtgg ctggctactt gaccgcttgg agtaatattt ttcaatatat
    17161 tgtcgtagga ataagtgaag tgattgctgt aggatcttat atgaattatt ggtggcctga
    17221 tttgccggca attattcccg gaatcattgt cgtcttgttt cttatgctgg caaatcttat
    17281 ttctgtcaag gcgtttggcg aattagaatt ttggttttcg atcatcaaag tcataacgat
    17341 cattttgatg atcattgcag gtcttggggt aatcttattt ggatttggta atcatggtca
    17401 ggcagtaggg atttcaaatc tttggaaaaa tggtggattc ttcactggag gcgtcaaagg
    17461 atttttcttt gcattatcga tcgttgttgc ttcctatcaa ggaatcgaac tgatcggaat
    17521 gactgctggt gaagcagaga atcctaaaaa gacgatcatt gaagctgtcc agtccactat
    17581 cggtcgaatc ttgatttttt atattggtgc tatttttatc attgtgagta tctatccgtg
    17641 gaatcaattg agtgagattg gttcaccttt tgtacaaact ttttctaaag tcggcattac
    17701 atttgctgca ggactgatta attttgtcgt gattacagcg gcattatcag gttgcaattc
    17761 agggattttc agcgcaagtc gtatggtcta tacacttgcc ataaatggaa agatgtctaa
    17821 aaaatttctg aaactatctc gtcacggtgc gcctttttat cctgtcgtag caatctcagg
    17881 tggaatctta attggtctga tcttaaatta tcttctacca atgttcatca accagtcaga
    17941 aaatattttc gttttcgtat acagctcaag tattttgcct ggtatggttc cttgggtagt
    18001 gattttgatc agcgagattc gcttcaaaaa gaagcacgca gataaaatgc atgatcatcc
    18061 ttttaaaatg ccactatctc cttatacgaa ttatgtgaca cttgcttttt tagctatcgt
    18121 attgattttc atgtttatca atcctgaaac gagaatctca ttgattattg gactcgtttt
    18181 cttgctttac atgacgatcc attactttgt acgcgaaaaa agaaccggaa aataaaaaaa
    18241 gaacgaagct tcaccttagt ggaagcttcg ttctttttta ttgcttttat caattcaatt
    18301 ttagcgtctc accgggagtc aggaaataat tctccatgct catcccattc agcgacaaga
    18361 tcgtttctac tggtacgcca gttcgttcgg ctatttgatt tggaccttct ccttccaaaa
    18421 ctacggttgt cgcagcctgt gaagtcgcgc tgttggtatt agtttcagag gaatctgttg
    18481 tgtcttgtgt tgttcgagct tgcatttcag aagcttctac cgactctgct gtctcagaat
    18541 cagaagatgt tgtgtcttgt gtgcttgttg actctgcttg aagagaggcg ctagtctgca
    18601 aataaatatc ggaaatctta gcgacatgat tcgtataatt agccgataat tgattgatca
    18661 aagtatctaa gtctacaccg tctttatttt ctgctgcctg atacgctgca cgtaattttc
    18721 tgatcccttc gtcggagatt gcttgaagct cacgtgcttt ttggttagca actgctgata
    18781 aaccagctat tccctcttga tttccctgaa tttctgtctg gtattcttca atcaatgcag
    18841 gcgtcttttc ttcgatcttt ttcgaataat catttacgat tgcttgaagt tgctctggca
    18901 aaccatttgc tgttttttct tcagaagttt gtgtctcttt tgttttagtt gatgactcac
    18961 ttgtttgttt cgtctctgtt ttctttgtcg ttgtttccgt tatggtcgta cttttcgctt
    19021 ctgacgaatt ttttccatga aaatatagac ccgcaactcc tcctgctatg atcaaaaaca
    19081 cggcaactgc tgccccaatc atgatcatcc gcttacgagc tgcctgtttt tgctgtcttc
    19141 ttcgggtcat ccgaacattt tctccccact cattttcatc atacattttt ttcaccacca
    19201 atttttatgt ataatagcgt tatcaaacgc ttcatattct tattgtagca aataattgtc
    19261 gctgtgcaca tttttatctt tgttatttat aagaaaattt caccagttga gatgattcca
    19321 agattgtccg tcgatttctc cttgcagctg cattgttcgt tcgtctatct cagccatcag
    19381 tttctttatt tcatataaga gcgcacggtc ttgatattct gatttttcgc ttaattcatc
    19441 taattgttgg atcagccaat catttgtcat aatgaagttc ctttcatttc ttgcagtgta
    19501 aaggtcaagt cttcgatctg ctcttttgcc tcagtcagtg cttctacgat atatgcttgt
    19561 ttttcagatt cttcttcctg cattttctga ttttcctgta ctctttgaat aaaccagtca
    19621 atccgctgag tcagcgatgg tttgccttcc aatgagagat actgctgata agcaattagc
    19681 ttctcccaac gtttttcctg ggataaatac ataaattgtg ctaaaacgaa tggcggaaga
    19741 taggtcatat ggaatttatt tgcgattcgc tgatacggcc tcaaaaattc ggaaatcgta
    19801 tattcttctt ttcctccagc ttggtattct ttttccgcca cacctgttgt caatacgatt
    19861 cctagttctt tcccttttaa tacatgtgct gctcgttcca agacattatc ttgccaaatt
    19921 tttaaatgag caggagaact ataccagtaa aacggaaact ggaaaatgat ccgatcatgc
    19981 tgggccaaga gctgtagttc agtctctata tctatttttc cgtctggata acttgattcc
    20041 aaatgatgcc aagtagctgg taaaccagca gaagcttctt tgaaaaattg ctgatttaaa
    20101 gattcttcga tcgttggatg gctaatgatg ataagtgtac gcatcccttt tcctcctttt
    20161 tagtcttcgc tttacagtgt agcataaccg ccacaagttt cttttgccga tgcttgtcat
    20221 tttaaccaga ctaatcaggt tgtccaagaa actgcggttt gtttttccaa ctgttttttc
    20281 aaggtatcca aagcaatatt cttaaaattt tcgtttttca tacgtttacg atagttcgta
    20341 gccgtttctc cggtactctt tttgaacatt cggctaaata cgactagact attgaaccct
    20401 acttgatagg caatactttc cacggattca cccgtcagag aaagaagaaa cgcccctcga
    20461 ttgatccgta ccccgatcaa atattccttg atactggtac ccatatgatt tttgaatact
    20521 cgcgacaaat ggctccgatt gaccgctaaa tgctgggcga tttcctcaac agacaatttt
    20581 tcagcataat gtgcctcgat gtatttgact gtttcaacag ctaaagagga atgaaccttt
    20641 tgtacaccac cgctgacctt tccgccatct tttaaaagga ctgataaaaa acggtaggtt
    20701 aatgctgtta actgtaattc attttccaag gtttcttccg tatctttcat gcattctaaa
    20761 ataatgtcga tatatttttg tatgtcagaa gagaccatcg tgtattggtc ttctctgaaa
    20821 agcgactgcc gaatgatttc ttctgcagca ctcccaccaa atgaaagcca gcaatacatc
    20881 cacggatctt ctccatctga taagtaaaac gtcgagtctc ctggacgaat caagaacaga
    20941 tcaccttttt tcaattggaa ttgttgattt ttcacatgat aagatccttt gccttccatc
    21001 acgacatgca ggatgtaatc attgcgaata gcaggaccaa aagaatgaaa cggcatcgtt
    21061 ttagagaaac cacaaaaatc aaaatacaat tctttttcta cttgttgatg ttcctttttt
    21121 aaaaaaatcg attgctccac gtctatccct ccttactcct ttagtataat gcaacaaaaa
    21181 gttaaataaa agtcacagaa atatattaaa aaggaagcga tttcttgtta agtttaagtc
    21241 attaaaagat ctttgttatt cgttgtaacc ggtttactta gtattatata ttgaacagga
    21301 gaggaataca gattatgaaa agcaaaatga tccaacgtgt gtcctacgct ttaggcgctt
    21361 ttggacacga cacattctat gttacattaa gcacttattt tatggtattc gtgacaagcc
    21421 agatgttcgc aggaacagat aaggcaacga atgcaaaaat gattgctaca gttacaagct
    21481 tagttgtagg tatccgctta gttgaaatta tttttgatcc tttgattggt ggcatcatcg
    21541 ataatactcg tacaaaatac ggtaaattca aaccatggtt agttatcggc ggcgttgtta
    21601 gttccgtact cttggtagca atctttacca atttctttgg cttagctact cataatacga
    21661 ctttatttat catattattt gcaatcgttt tcatcttatt ggatagtttt tattcattta
    21721 aggatatcgc tttttggtca atgattccaa ctttgagtac ggaaacaaag gaacgtgaaa
    21781 aatttgctac gtttgctcgt ttcggctctt ctctaggtgc aaatggtact actctagtcg
    21841 ttgtccctat cgttactttc tttacctatc ttgttactca taaacatatt gaaggcgctt
    21901 caggctggtt ctggttcggt gtgattgctg ctgttatttc aggcggtact gcgattatca
    21961 ctgccttggg cacaaaagaa gtcgatactg cgatccgtca gcaaaatgaa aaagctggga
    22021 tcaaagatgt gttcaaagca gttgctcaaa atgatcagtt gatgtggctt gcccttgctt
    22081 atatcgctta tgcgattgcc aatgtagcaa caactgccgt attattctac ttcttcaaat
    22141 atgtacttgg ccaaccaact gaattttgga tcgttggtct agttgctgcc ttacttggtt
    22201 tagtagctgt tccactattc ccaatgctta cacgcgtcat ctctcgtcgc tacgtttacc
    22261 ttggagggat cgcaatgatg atttcttctt actttttctt tacgatcgca ggttcaagtt
    22321 tgccaatcgt tatcatcggg ctagtattgt tctacttccc tcaacaattg attttcttat
    22381 ccgctttgat gacgatcaca gactctgttg aatatggtca atggaaaaat ggtatccgta
    22441 acgaagctgt tactctatca attcgccctt tactagataa aatcgctggt gctttgtcta
    22501 acgggatcgt agggtttgtc gctagcgctt ctgggatgac tggtaatgct actgctgctg
    22561 atatcactgc tcatggcgta acgactttca aagcttatgc attctatgct cctgctgctt
    22621 tgatgatttt ctccgctatt atttttgctt ggaagattac attgacagag aaaaaacatg
    22681 cacaaatcgt tgagaaattg gaaaacaaat tggctccagc tgatacaatg gaagatgaac
    22741 ttcacgatgc agtagttcct tcccattaag aaaggatctt gaaaatgaag attacagaaa
    22801 aagattttgg ccaaggttat cacttgataa ccttggagaa caaaaacaag ctagcacttt
    22861 ctatctctga tttaggtgct agaatcgtca gtttaaaatc aaatgatcga gaattagttt
    22921 tgggatttga caccgctgaa gaatatatcg aaaaagatcc gtatatcggt gcttctatcg
    22981 gtcgcaccgc agggagaatc gaaaatggcc acttttctct caatggaaaa acttaccaat
    23041 tagccacaga tccaaaaact ggacataatc tgcatggtgg tgctcctgga tttgaattaa
    23101 aaaaatggtc ttatgtcatt ttgaatggcg aaaatgaagc ttctgtcatt tttactacta
    23161 caagtcccga cggagaacat ggttttccag gtacaatgga tgtggaaatc cgctatactt
    23221 tgacaaaaga taatatctgg cgagtgacct ctcgcggcac cagtgaccaa gatactttat
    23281 tcaatccgac aaatcatgtt tacttcaact tgacgggaga tgcttctcag tcaatcgatc
    23341 aacatgagct ttggctcaat agcgaagctt atgctccttt gcgaacagat agtattccta
    23401 taggggtaaa agaaaatgct gcaggaagtg ctttcgattt tcaaatacct aaaaaattag
    23461 cgtccgtttt tgctagtgat ttggatcaaa aaaatcttgt tgacggaatc gatcatccat
    23521 ttttcttaaa agaaaccggc ttgggtaaag aagccgctcg cttgactagc cccgataaaa
    23581 gaatccaagt agatattgct acagatgctt ctagtgtggt tattttcact gcaaatttcg
    23641 gcacagaaac accagaaatg cgcaaccgaa aactggcaca tcacggtggc atcacatttg
    23701 agactcaaac agctccaggt gcagagcgct tctcagcatt tggttcgatt catttaaaag
    23761 ccggatcagt atttgaaaca gtgacagaat tcaaaatcaa aacaagaaag gaataactca
    23821 tcatggaaat caaaagaagc ttaaacacaa aatttgccga aacattcgga cctaaaaaaa
    23881 ctacacaata cttctcacca ggacgcatca atttgattgg tgaacacaca gattacaatg
    23941 gaggccatgt cttccccgct tccatcactt atggaacgca aggtgtagca gcacctcgag
    24001 acgataataa aatattagtt tattccacaa actttgacga tatcggtgtc attagtttta
    24061 ctttagatga gctagaatat gataaaaaag caaactgggc aaattacgta aaaggaatgg
    24121 tccttaaatt aaaagaagct ggacactcaa tcgatcatgg gtttgagtta ttagtggaag
    24181 gaacaatccc taatggtgca ggactttcca gtagcgcttc attagaatta ttagtaggtg
    24241 ttgtattaga agatctgttt gatttaaaaa cagatcgctt ggaactagtc caaacaggta
    24301 aaaaagtaga aaatgaattc atcggtgtca attcaggtat catggatcag tttgccatcg
    24361 gcttcggtga gctagatcat gcaatcttat tagatacaaa tacgctgaaa tacgaaatgg
    24421 ttccagtgaa actagatggt tatgcaatcg tcatcatgaa tacgaataag cggcgggaat
    24481 tggcagattc aaaatacaat gaacgccgta gcgaatgcga agaagccttg gcacgtttgc
    24541 aaaaaacttt gcctatctct tctttaggag acttagatga agaagaattt gaatcaacta
    24601 ttgaccaaat cggcgatgat acattgatac gcagagctcg ccatgccgtt tctgaaaatc
    24661 agcggacttt gaaggcaaaa gctgaattag aagctgggaa cttagaagca tttggtcaac
    24721 tgttaaatga ttctcaccac tctcttcgct atgattatga agtaactggg atcgaattag
    24781 atacactagt agatgctgct caaaaacaag aaggtgtctt aggtgcacga atgacaggag
    24841 ctggatttgg tggctgtgcg attgctcttg tcaaagaaga aaatatacct gccttcaaaa
    24901 acaatgtcta tgatgaatac atgaaagttg tcggctatgc tccggaattt tatgttgcac
    24961 acattggaaa tgggacaaca aagatcgatc cagaagctgt tcatgtttga taaaaaaatc
    25021 aacgatctca gctaaaaaca aatagataaa aataacctct cagcaatttc caaatgtgag
    25081 ccttttgctc gtatttgaaa attgctgttt tttattgaca cggaaagaga acgtgtgttc
    25141 taattgtgtt gaagaggtga ttgttatgtg ggcgaatcaa aatccggtat ttgtttatga
    25201 aaaagaacct tcaagagata ttttatgtat tgactgcaaa tctttttacg cctccgtaga
    25261 gtgcgttgaa aaggatcttg atccccttac aactaaatta gtagtcatgt cctatccgtc
    25321 cgattcgaca gaaacacggg gtagcggatt aatcttggct tccagtcctg cagcaaaaaa
    25381 agcttacggc atcaccaata tcagccgtgc cagagatctt cccttcccct atccaagtga
    25441 tttatatatt gttgccccaa ggatggccta ttatatggaa aagaacagag aaatcaattc
    25501 tatctataaa aaatatgcag acgaagcgaa ccatcatgtc tattccgtcg atgaaagctt
    25561 ccttgatgta acaaatagca tggcactctt tggtaaaaca aatgcgtacg acatggctaa
    25621 actgatccat aaagatgtgt ttgagcagac cggaatctac acgactatag gaattggcga
    25681 taacccgcta cttgctaaac tagccttaga caatggctca aaagacggaa agcaaatgtt
    25741 tgctgaatgg cgttatgaag atgtaccaga aaagttatgg aaaatctcag atatcactga
    25801 cttttgggga atcggcaaac gaacagcaaa acgtctgaaa caaatgggta tacattctgt
    25861 ttatgattta gctcacgcgg attattatca cttgaaaagc aagctagggg tcatcggtac
    25921 tcagctttat gcccatgctt ggggcatcga tcgaagtttt ttgggacaag aatatacacc
    25981 aaaatcaaaa agtatcggaa atagtcaaat cctagataga gattatacaa gacgagaaga
    26041 aatcgagatc gttatcaaag aaatggccga ccaagtcggc actcgcttga gacgatctgc
    26101 agcaaaaaca caagtagtca gcttatgggt aggatactct ttaggctatc ttgatccaaa
    26161 tggcaagacc gggtttcacc agcaaatgaa aatcgaagcg acaaatgcta gcagagatct
    26221 agcagatgct ttattgacca ttttccacca gcattaccac taccaggata ttcggcgtgt
    26281 aggcgtgaac tgttccgacc tcgtatacgc gacaggttta cagcttaacc tttttgaaga
    26341 tcctgaaaag cagataaatg aagcgaaagt tgattttgtt gtcgatacga ttagaaaaaa
    26401 atacggcttt caatcaatca tccatgcgca tagtctcttg caaggaggac gcgccatcgc
    26461 acgtagttct ctcgttggcg ggcatgcagg tggtatgagt ggattagaag gtggaaaaga
    26521 tgagacggac agcaaaaaaa ttcattgact ataacgagta tcgagatcgg ccatttggat
    26581 taaaatgggg gactgctttt gcgatggaag aactagtcaa cggtatcaaa aaaaatgaag
    26641 aagaagcacg caaacagcct cttcctaaac aacaaatgac attgcaagaa atcgatagta
    26701 tactgacaga agccttttta tctcgtaaag cagtaatcat tcagctcaat ttaaaagatg
    26761 aatttggaag actcttggat gaggtcgaag ggcacttcat tggtgaagcc tatgaagatt
    26821 actttatgat tgaccatcag ccgatattgt gggaagacgt acggtatatt gagttaaagg
    26881 aaacaaaaaa atggtttgtg acatgagagg ttgtgacaga agtgatcaac ttcaaaaaat
    26941 aagaaaggat ttttcgaaaa ttgcttctta aatttttgtg gaattttggc ttatttttcg
    27001 aagaagcaac ttctggaaca acgtatatta gatatcagag gttgtgaaaa agtcgcttag
    27061 ttttgagtaa caagccaagg cgctgatttc acaacctctg tctatctatc catctattcg
    27121 gtaagattca tgcatgacgt cttctttatt tagtatgtag agcccttttt cttctgacca
    27181 ttcaacataa atcagctgtt ttacatctgc atagccttct ttcttcaagt tctccataag
    27241 ccatgcttca gtcaattgat tggactgaag cactttatgc tgaatttgcc cttcatctac
    27301 aagcaggatc gataaagctt tgtcttcatc tgattttttc aatacactca tttgaccggc
    27361 attctctagg ataacatgtt tggcattttc aagaaaaaag cattcttgct gtcttaagat
    27421 tgctcgcaac tgctccatct cgatatggtt atttgtcaac tctgtcatgt tgatgacgcc
    27481 gtctttgatt agaacagatg gctcgccttt gacccaacga ttgacctttt catttttttg
    27541 gacgatacgt tcgataccat aaatcattac tgcccaaagc gcaatggcaa ataggacatg
    27601 ccctacatgg acattgtcat cataggttga ttcttctaag atcccaccta aaacaagcgt
    27661 atagactaaa tcaaacggtg tgatttctga catggatttc ttcccaagca aacgtaccac
    27721 taataataaa ccgatcaacc cgaacaccag tttcattgta attgaaaaaa tcattttttc
    27781 tccccctaac tatctgttaa ttaaattata tatgctttct cacgaacacg catggaatat
    27841 acaaggaaga aatgtatcct tttactaaaa aaaggactgt gacactgtag tgacccccaa
    27901 aagttagact tttttggagt ggagaaatcc actccttttt tttatgctct aaaatgatat
    27961 ttttacacaa ccgttacggt tgttttacga aattggacga gactttgcca gtttaatttc
    28021 tgttttatcc gttcattatt gtagtaatag atatagctat cgatggctga ttttaattcc
    28081 tcgaaacagt tataaacttt cccgtgaaaa atctcttgtt ttaataagcc aaaaaaattc
    28141 tccataagtg aattatctaa gcagttccct ttccgagaca tgctttgaaa gattttgtac
    28201 tccttcaatt tgtttctata agctttcatt tgatacgccc aaccttgatc tgagtgaaac
    28261 gtacgacgat agggacaatc gttagtggtc tggatagctt cctccaaacc ttccattacc
    28321 gctaatgcat tgggcttttc agagatacga taggataaaa tctcactatt gaacatatcc
    28381 ataaaaggat ctagatacaa tttcttttga cggataatgc ctttggcatc cacttcatgg
    28441 tatttaaatt cagttgtatc cgtcgtgatt ttctgatggc agatactggt gtagaaacga
    28501 cgatggatcc gatttttggc tactgctcca acttttcctc gataagaatt gtagcgacgt
    28561 gatttacgcg tgtatgccgt tacttttatt cctagcttct tgatcaagcg ctgaactttc
    28621 tttttattga tagagaaacc gcggtttctt agttcattgg tcatccgtaa acagccataa
    28681 tccttgtgct tctcccgaat tttaagcatt tccgcttcaa tctcttgatc tggattttta
    28741 cggtccaatc gcctttgcca tccaaataat catgaacgat ctttaattta agttcaaaag
    28801 tatatttaac cataaaaaat accgacctcc aaaagttaga ttttttggtc taacttttgg
    28861 gggtcggtac acaaatcgtg tcacagtccc ttttttgaaa ataaacggtg ttcaaaagct
    28921 tgcatctgcg gtaataagtc cagccaagtt aaaaacataa gaagctgttt ttacttggct
    28981 gttcttatta cttgatgcaa ggcagctttt tcacaacctc ttttcaaata tttcgttttc
    29041 ttattctaca aatggttctt ctcctaacgc ttgttgagcg gctagattca acatgctcca
    29101 ttgtcggtca aagcctggct ggaagaagaa gtcagcttct gctagttctt ctaaagtcag
    29161 tttgttttgg atcgctagtg ccaatacatt tccttgacct gtaacatcat aggtagataa
    29221 tactgctcct cctagcaatt gatgggtcat tggatccgag aataattgga tggacacttt
    29281 tggatttcct tgttcttctg gtacatattt tggtcgtaac gtatcttcat aataagacac
    29341 tcgtacatct actcctgctt ttgctgctgt aaagctattc aatccgcttg ctgcaaaatg
    29401 atagtcaaag acacttaatg cagaggaacc tacgactccg ccgaacggtt tgtttggtac
    29461 ttcttcaaaa agatgtttta ctacataacg tgcttctcta cgtgcaacag tcgctaaagc
    29521 gatcggcatt tttttgcgtg ctgggataga ataagcaagt gtagcatctc ctactgcata
    29581 cacatctgga agattcgttt gcaagtattc atttgtttgg atccagccac gttcatctaa
    29641 gtcgacgatc ccttttaacc attctgtatt tgccttcaca ccggcagctt gaatgactag
    29701 atctgctggg atttcttttt cacttgtttt gattgcctca acttttccgt taccagtaaa
    29761 agcttcgatt tttgcatttg tcaaaacttc aataccgttt tcatttaggt gttgttctaa
    29821 aatatctgtc atctcagcat ctaaataagt gcctaaaggt ctatcgatca catcaagcaa
    29881 tacgacttct ttcccagctt ttcggcttgc ttctgctgct tcgatcccaa tgtaacccgc
    29941 acctacgaca gcgatttttt taatagccgg atcatttaat ttttctttga ttttggttgc
    30001 ccaattgtat ccacgcatca agtagacatt ttctagatct gctcctggta ctggcagatt
    30061 gtttggtttg acaccagaac tcaaaatcaa tttgtcataa ggatattctt ttgtttcgtt
    30121 atctgatgcg ctagtaaccg ttactgtttt tttatcggca tcgatcgttt ttacttcgtg
    30181 attatttaaa atatgaacat tggattgcgg aaagttttct ggtctgaaat tacgtacatc
    30241 atttacatct gttaccttgt cttctaaata cagctccata ccacatgaca tgaaggaaat
    30301 atagtctcct gcttcaaata gcgtgatatc tacattttca ccgtatcgtg tcaatagttc
    30361 caagatcgat tgatgccctc catgagatgc acctacaatg acaactttga ttttttccat
    30421 tgatgaaacc tccttgaata ttcttttaaa atcattctaa acaatttaaa cttaacatta
    30481 cattagttat gaatcaaaag aaacgcgttc atttgaacta aatttaaaaa acaatcgtct
    30541 ccttgcagaa tataccgcaa aattaacgat tgtttttttg ataaaatcta tgaatcactg
    30601 ttctgttaaa aagtctttga tccgtttgca ggcctcatgt aatttttcca tgctgctagc
    30661 ataagaaatc cggatataac cttctccttc tgggccaaat gcaattcctg ggatacacgc
    30721 aacttttgcc tgttccgcta attctacaca aaactgccaa gagtcagttt gaatggcagc
    30781 tgggagtttg caaaacaagt aaaatgcacc gtttggctgg gtcacttcaa atcctaaagg
    30841 cgccaattgc tggaccagat aatctcttcg tgtttgatat tgctctttca tattctcgct
    30901 atctttcacc ccatttatta gcgcttcagc cgcagctttt tgcgacatcg ttgtagcggc
    30961 agtcaccaga tattgatgga ctttaattag ttcgtcaata agggcttttt gagcaaaaat
    31021 aaagcccact cgccaaccag tcatcgcatg tgacttggat aacccgctta tcacgattgt
    31081 ttgttctgga agataagtag ctatggacat atgcgttcca ctataagtca attcagcata
    31141 tacttcatca cttataacaa ataccggata tttttttaaa acctcagcga ttgctttcaa
    31201 ttgttttgca gacaatgtcg tcccagtagg attgttagga tagtttaaaa tgactgcttt
    31261 gacagctgat ccatattgtt caaatgctcg ttcaaattgt tccggctgac agacaaaccc
    31321 tgtgtcagaa gtatctatcg ggatcaattc agcaccagct agttccacta atggctgata
    31381 tcctgaataa gcaggcgctg gaataagaac cttgtctcct tcttccaaaa cagataacaa
    31441 cgcagaggca atcgcttccg ttgcaccaac tgtcgtcaaa acttccgttt gcggatcata
    31501 agttaatcca taacgctgtt gctgaaatat acaagccgct tcccgcagtt cctctaatcc
    31561 tctcattccg gtatagtgag aaaagtcttc ttcaatcgct gctattcctg cttgcttgac
    31621 atgttcagga gttggaaaat ccggttctcc cagggtgagt ttgatcacat ctggtatcga
    31681 cgatatttgc tgatcgaatt gtcgtatttt tgatacttct attctagaaa gcctaggact
    31741 aaatcgattg gataaattca tcattattta ctcgctcctc ttttgaactg ctatcgattt
    31801 ttacaagaag attttctgta aaaagaatcg ttttgtacca ttctacacca ttttctaaaa
    31861 catccatatc aaaatcgaac gtcggatcat gtaaagcagg ggtatcaccg acacctaaaa
    31921 agaaaaatac acatggatat tgttgcgtat atatgccaaa atcttcggct tgaagaactg
    31981 gagcatctaa ttcatgtagt ttgtttgaat ctaacagtgc tgcatataag cctctatggt
    32041 tgattacagc tggatagccg tcattatagc gaaaagaaat agtagctgta gagtgaaact
    32101 gttctgctaa atggtctaat cccctcttca aataattttg catatctgaa ctgtaagaac
    32161 ggatacttcc ggatacaata acttctccag ctaaaacatt tcggatcgtt ccaccttgga
    32221 tttggccaaa tttcattaga tgattccact ctgccggtaa ttgccggtca aaatcataaa
    32281 cattcttcaa aaatcgtaca gctgcctcca gactatcgat tcctttttca ctagaagcaa
    32341 tatgtgcaga ctggccttta atgataatgt ctgtttcact gctttgtgcc atcaaaggtc
    32401 ctggtcgaga gaaaacttct cccttagcta gtccaggcca tagatgaaag ccaaatattg
    32461 cttgtacttc atatttatcc aacaatcctg actgaataac gctttgtgcg ccaccggaaa
    32521 tttcttctga tggctgatag atcagtacta cattataaat aagatcctca atgtgtttag
    32581 ttataaagtc agtcaaccct aaaagcatcg ccatatgtcc gtcatgacca catgcatgca
    32641 tataaccttc atgcttagaa gcaaaagaga gattcgtttc ttctttgact ggcagtgcat
    32701 cgatatctgt tcgaaaagca atcgtttctt cttgctgatt atcaaaataa aggagtagtc
    32761 ctgtttcgcc gatttcatgg ataacggcct cgctgttttt tacttgttca tataaatatt
    32821 tttttgtctt gaattcatga aacccgattt caggaatttg atggagtgcc attcgatatt
    32881 ctttcagcat ccgtattcac catcccttcg tagataccct tcactactgt ttcatattga
    32941 ttattcggta caccgatgat cagattcaac tcctgtgctc cttgtgataa gatcgatgtg
    33001 cgaatttcta atttgttcaa tatcgataac actttcccag ataatccaat caattcttta
    33061 tgcggacccc caacgacaga gatcaaagct aagtcttcga tcacgacgat ttcttccacg
    33121 ccaagtgttt cttttaattc tttcgtgatg agaaataact tatcggcaat cgcttctgct
    33181 gagacgatca ctccgatatt gtcgatccct gaaggaatat gttcgattga tatctcatgt
    33241 ttagcaaaaa tgctcattgc tttccagata aacccgattt catcggacat atgacgtttg
    33301 aataaagtga tggaaagaaa atccttgcgt ccagctattc ctgtcagtcc attttccttt
    33361 tctatttcgt gattcgatat ttttgtccct tgagcgaaag gatcattggt attttttatt
    33421 tggatgggga tatcagcctc ttgaactggg aaaacagctg cttcatgaag aacgttagcc
    33481 cccatataag ccatctctct cagttctcta aaagagattt cctcgatgat tttaggatga
    33541 tcgatgattc gcggatcagc catcatgatt cctgaaacat ccgtccaatt ctcataactt
    33601 tccgcttgca acatcttcgc cagtatcgcg ccggtaatgt cgcttccccc acggcccaat
    33661 aatttttctt ttcctgcagg gttcgccccg taaaaccctg gaacaaccat tttcggatat
    33721 cttttaaatg cttttgtgat ttcctgtgct gttttttcct gatcgatttt cccatcatag
    33781 tcaaagaaaa tcaggtcttt tgcgtcaata aactggtaac caagatactc agccatcagt
    33841 tgagcagtca gatattcacc tctacttact aaataatctt cagttatctt ttcgtcttcc
    33901 agttgtttct gtatgcgtgc tagttcatct tcaataggta actgcagggc aagaacatct
    33961 cttacttgaa tgaaacgatc acaaatcctt ttccaaaggg gtgtccaatc aacatgatgc
    34021 tgaaggtaag cataaatcaa ataaagtaag tctgttactt tgtcatcatc tgacgtacgt
    34081 ttgcctaaag cagaaacaac gatcacttgg cgattgggat ctgaaagaac aattgtacgg
    34141 acttttttga attgctcttc atgagacatc gatgttccgc cgaatttcgc tactttcagc
    34201 gtattactca tcttgccacc tccgctattt tctgcattaa agctgcagca atctgtacgg
    34261 cattcgcagc ggctcctttg cgtatgttat cggcagtcgt atagaacaac aatccgttct
    34321 ctaaagaagt gtcttttctg atcctcccaa cataaaccat atctgttcct ctagcaagaa
    34381 tgctcgtcgg atatttatgt gctgctagat catcttctaa ttgaatccct ggaaactggc
    34441 tgagacactc tctaatttct tccgtcgtaa actctttttg cagttgaact gccacagaga
    34501 ctccatgtcc attttcgatt ggcacacgta cgcaggttgc tgatactggc aaagcaggct
    34561 gatgcagaat cttacgggtc tcatttatca ttttctgttc ttcttttgta tacccatttt
    34621 ccaaaggctg atcgatttcc ggaatcaccg tttggctaat attataagga tacaaaactg
    34681 gttcctcgtc attttgcgta cgatgaagat cttcaatgcc tttttgcccg gaaccagaaa
    34741 ctgcttgata ggtcgaataa ttgactcgct ggataccaaa ggcttcttgt aaagctttaa
    34801 gcggaagtac cgcttgaatg gttgaacaat ttggatttgc aatcagccga ttcaatgtat
    34861 agtcttccag attgacctct ggaacgatta atggaatatc cgaatcttcc cgccatgctg
    34921 aggaattatc tatgacaaat agtccctgac ttcgtgcgat tggcgcaaac tctttggata
    34981 cagaagcacc tgcagaaaat agcgctaaat catatccttc aaatgaagtt tctgtcaatt
    35041 cctgtacagt gtgtttcttt ttcttgaata cacaaacttt accggctgaa cgttttgaag
    35101 ctaataattt caatcgtcct actggaaaat catattcttc taacactttg agcatcgttt
    35161 ggccgactaa tccggttgcc cccacaatac aggtatctat ttcgcgcatt tttctccatc
    35221 tcctctataa ttcgcgtaac gcagcaatca atgctgtatt ttcttttgtc tgatcatcac
    35281 ttatttttaa tacacgtgca ggtattccac cgacaacagt ttctgctgcc acatcttcta
    35341 aaaccactgc tcctgctgcc acgactgcat cttttccgat atggacacct tcaacaatca
    35401 ctgcattcgc acctaccagt acgccgtctt ctacgataac cggtttggcc gatgctggtt
    35461 cgatcacacc tgctaagaca gctcctgcac caatatggca gtttttgccc actgtcgctc
    35521 gtccacctaa gacagcaccc atatcaatca tcgtgttttc accgattact gcaccaatat
    35581 tgataatcgc tcccatcatg atcacggcat tgttgccgat tgacacttga tctctgataa
    35641 tagcacctgg ttcgatacga gcattaattt ttttaatatc tagcaaagga actgcgctgt
    35701 atcttgcagc agtttcgatt tcgatttcaa tgattttttc tgattcagct tctaaaaccg
    35761 gagcaatcgt ctcatagtca ccaaaaacaa cgaagctgct tccttcacca aaaactttac
    35821 tttctttaaa ttcgattggc tcggttacat tcagatagac tttcacaggc gtctttttag
    35881 atgccgtttg aatgtagcgg atgatttctt gagcttccac gttttttaca cccctttgtc
    35941 cattaataaa tcttctaatt tgtaataacc tggtgactga tctttcaacc agtccgctgc
    36001 ttctactgcg cctgcagcaa agattcgatt agaaaaagat tcatgtttga tcgtaaatat
    36061 ttcatcagta gcagcaaaca atacatcatg ttcaccaggt aaagaacctg cacgaatact
    36121 gtgtacacca atttggtttt cttctctttt tttcccttgc cagttgtata cgggctgcag
    36181 cttttgcact tcttggattg tttgaagcag catatttgca gtaccagatg gtgcatcttt
    36241 tttacgacta tgatgttttt caatcagttc gatctgccag ccttgcaaca ttgcagctgc
    36301 ttgcttgatt agttgattca tcaccatgat gccgaacgaa aaattagcac tatacatcac
    36361 aggtacatgt ttggcatgtt cttttatttc ttggaactgt gattgtgtat aacctgtcgt
    36421 gccaatgact aacggaagtt gatatgataa gctatacgaa aggattttct ctaaattatc
    36481 tggatgagaa aaatcaataa gcagttctgg cagttccgta aaagcaagcg tagttgcttc
    36541 tttaggtgcc gtccgtaaaa gaaggaccgt atctcctctt tcttgtgcaa cttcttcgac
    36601 tctatttccc atctgtccac tgccaatcag tccgattttc atttttcaac cgtcctttct
    36661 tttaacaaaa gctgagctaa ttgtttcttt ttctcttttg aaagagaaac taaaggcagg
    36721 cgtagaggtc cggaaggtaa gtctaataat gacatggctg ctttgacagg aataggattg
    36781 gtctcactga acaaggcatg gatcagttca agtgcattta attgcttttc ttttgcttgc
    36841 tgccatcttc cgtcctgcgt atcttttact aattcatgga ctattttagg ttggatattc
    36901 gcccatacac ttattacacc gcttcctcct acactcatta ctggtaggat caaatcatca
    36961 tttccactgt aaaggaagaa ttcttctcca atcaaccgag cggcatccat cacataagcc
    37021 atatctcctg aggcttcttt caaaccaatg atattaggat gttctgctaa atttactaat
    37081 acatggattg gaatcgacat gcctgttcta gaaggaacat tatacaaaat aagcggaatc
    37141 ggtgaggctt ctgcaattgc tgtaaaatga gcagctagtc ctgcatcact tgttttgttg
    37201 tagtaagggg tgatgaccaa aagtgcgtct gcccccaaag aagcaaaatg cttcgctttt
    37261 tcaatcgttt ctttcgtatt attcgttcca gctcctgcaa tcaccggcac acggccagcc
    37321 actttcttta ctgtcagttg aaggatctgc tcctcctcag attgtgtgag cgtagaagat
    37381 tctcctgttg tacctaaaac taataatcca tctgtttgtt catctaaatg gaattggatc
    37441 aatttttcca aaccagcata atctactgat ccctcttcat tcatcggcgt gatcagcgcc
    37501 acgatcgaac cttttatcat cttcattcct ccaatattct tgtccattca tgaactgctg
    37561 ggccagccat ttgtatcgca tcctcaccag agatcatcaa gtctccttgt tccaagtgaa
    37621 caactacctg atctgctgaa attttcccag tttccttagc aaccacataa gaggcacagc
    37681 aacctgtacc gcaagcaagt gtccaaccta ctcctctttc ataggtacgg acgatcaatt
    37741 cttgttcatt gactacttct acaaagttga cattggtttt ttctttgaac aaaggatgat
    37801 gacagatcag ttcacctctt tttctccaga cttcctcacg cgcattttca acaaaaacaa
    37861 cggtatgaat cgttcctaaa aataaactag tgatcgttac tttttcacca ttgatctcta
    37921 tttcctggtt ttttattgga taagtttgat tagctttgat tttttccgga gaatcatctg
    37981 gcactcccat atctacgctg caataaaaag gtgagggatc caacaccgta atttttcttg
    38041 tgcctgctaa tgtctctacg ttgaattcct gttcattcat catgttctga tcatttacgt
    38101 atcgagcaaa acagcgaatg ccatttccgc acatcggcgc gcggctgcca tctttgttgt
    38161 aatagatcat ttccaacgga tcgattttta cggcgatcaa tccgtctata tcatattttt
    38221 cttttgtgca taaagaagcg gctaattgac tataatctgt gtcttctgcg taatctaata
    38281 agataaaatc atttccgcag ccattatatt tatgaaggat cataggaaac ttcccccctt
    38341 agtagatcag aaaatgcttg tctgcgaaca atcagtcttg attggccatt attgacaaaa
    38401 acaactgctg gtcgtgtcgc tcgattgtag ttgctgctca tcgagtatcc ataagctccc
    38461 gtggaataaa cagctaaaag atcacccgat tctgctttcg gcaaataagc ttctttaatt
    38521 accacatcgc ctgattcaca catttttcct gcaatcgtca ctttctctgt tttttcttcc
    38581 gacagttttg ctgctaaatc acaatcgtat tctgcctgat acagagctgg acggatatta
    38641 tctgtcatcc cgccatctac aaagtaatat tttttatgtg gtgtcttttt gatgaaacca
    38701 atcgtgtata gtgttgtacc agcttctcca acaatacttc tacccggttc gatcagtaat
    38761 tgacgaatgg tcagttttcg tttttccaaa gcttcttccg tatattcaat cagttttttt
    38821 agtgcctctt cgactgggat cggctgatca ttttgtgtat aacgaatccc aaaccctccg
    38881 ccaagattca aggaaagagg ttggtcaaaa tcggttaagt aattcgtcaa tttgtcgatt
    38941 tcagctaacc aagcagtaac atcaaaaatt tgtgacccga tatgagcatg aaatccttct
    39001 aactctagat agctgctttc ttttatcaac tgaagggctt gttggcactc tttactttca
    39061 tagctcatgc cgaattttga atcaatatgc gcagtgacga tatattcatg agtatgtgct
    39121 tctactccga cattcaaccg aagcatgata cagatttttt ttaaatagcg ttggcttaat
    39181 tctgctaata attcaacttc catcaaatta tcggcaacaa tatgcaacaa atcattttca
    39241 agtgcataga tcagttcctc tggcgtcttg ttgttaccat ggaagtagat agtatctcta
    39301 ggaaaatcag cttgcaaagc ggtatagatt tccccaccac tgacaacatc tagcccgaat
    39361 ccatattcac gaactaaatg cagcatctca atcgtttgga atgctttaga ggcgtaaagc
    39421 acttttgtat caaaacgttt cgatacaaag cctcgcttga atgacagcat cgtttgtctc
    39481 atcttttctt catcatacac atacagaggt gtcttatact tttctgccaa tgtgcttgct
    39541 gtgactccgc caattatcaa ttctgtcatt ttttcattcc tcttttcact ttttttccgt
    39601 ttttattgga atttcatttg ataaagattt gaattttatt ggaataatat taaacaaaat
    39661 tttctgaatt gtctagtata tttcgaaata tttttttaaa aataagaata aaaatggtta
    39721 taaaaacaaa atacccgaac tattagaagc tatttataca taaaaacata aattcaacac
    39781 tatttagtga tgaaaaaata ttttcgcttc aatatagttc ggaatagttc ggatattttc
    39841 aattttatga atcatttcaa tttcttcata aataagtgca gtttcttctt tctctagctt
    39901 ttgccattca tctttcaaaa tataaataaa atcaaatact tttttatttt tcaatttgct
    39961 gattccacaa aaaacctctt gaaaggcaga tccgatgatc tgcctttcaa gaggtcaagc
    40021 tctgttttca aattcttatc aatccgttag cgaattattt tgacgcacgt tttacataag
    40081 aaccttctgc tgtattgatt tccaacaatt catctgtttc gatgaagtca ggaacattga
    40141 ctactaagcc agtttccatt gtcgctggct tacctgaacc agtgactgtt gcacctttga
    40201 tggaaggttg tgtttccaca acacgtaata cgacagttgt tggtaattga acgccgatga
    40261 cttcgctacc gaaaaattgg atttttactt ccatgttttc taggatatat ttcatttctt
    40321 cttctactgt ttctacagga atttcatatt gctcatatgt ttccaaatcc atgaagaaag
    40381 ctgtatcatc catcgtgtac aaatattgta caggttttgt gtcgatatgt gctttttcaa
    40441 atttttcttc tggtctgaac gttgtgtcgt atgttgcacc tgaacggaca tctttcagtt
    40501 tcatacgcat aactgtattt cctttaccag gtttatggtg gcttgcatcc agaactttaa
    40561 tcagtttgcc gtcttgtacg aaagtcatac cggctcttaa atcacttgct gagatcatta
    40621 tttttgctcc ttcttttctt tatcataatc aactttattg tatcagacaa ccggccagaa
    40681 aactagagta ttctctatct tttaaggtct catgcctatt tgtcagaaaa ataaacacgg
    40741 gtaaacgatg ctatcgaaat atttttttct ttcaagcctt tgacttttat tttttttcat
    40801 gctatcgtta ataaaaattt tacttggagg gatacacatg acagtcagca accaaaaaca
    40861 attgaatcgt tgctgttgta tggtgcataa aagcagcata ctatttgtca tgtctattaa
    40921 ttgcccttca tagaatgagt accaggtaac ttatcttttt atctactcaa tttttctcta
    40981 tgtctttcaa ggagctgatt taatagtcag ctcctttttt tattatcttt ttttaggagg
    41041 cccacatgat tatctcgaca attacagaag ctattggttc cacaccgctt tatcgctttg
    41101 acaatcagca ctattctatg cctaaaggtt ctgctattta tgcaaaacta gaatatttaa
    41161 atcctggagg aagtatcaaa gatagattgg gcagttattt gatcaaagaa ggatttgccc
    41221 aaggaaaaat caatgaaaaa acgacgatca tcgaaccaac tgccggaaat acaggaattg
    41281 ggatcgctct ggccgcactc acatacaaat taagaacggt ttttgttgtt ccagagaagt
    41341 ttagcttaga aaaacaacaa ttgatgaaag cattgggagc aaagatcatc cattctccta
    41401 gtgagcaagg aatcatcggt gccatcagca aaagtaaaaa acttgcagag gagatatcaa
    41461 acagctatct gcctcttcaa tttgaaaata aagataatcc tgctgcttac tatcatacgt
    41521 tagggccaga aatctttcat gaaatcaaag aaaatatcca tagttttgta gcaggaattg
    41581 ggagtggtgg aacctttgct ggaacttcta cctttttgaa agaaaaatat cccgacattc
    41641 gaataatcgg tgtagaacca gagggctctg tgttaaatgg tggtgatcca gcccctcacg
    41701 aaattgaggg tatcggtgta gaattcattc cgccgtttct ttctcccctt tcaatcaatc
    41761 agatcgagac aatctctgat gtagaagggt ttaactatac taggcagtta gcacgagaac
    41821 aaggactatt agttggaagt tcgagtggtg cggcttttgc agcagcatta agagaaattc
    41881 gtcgtttacc acctggtcat cgtgtcgtta cgatttttcc agacgcagca gaccgctatt
    41941 tatcaaaaaa catttactta taggaggaaa gaaacatgca cattcaaaca aaattgatcc
    42001 acggaggcat cagtgaagat cccacaacag gagctgttag tgtacctatt tatcaaacat
    42061 ccacttatcg gcaagatggc gtcggccagc ctaaacaata tgaatattca agatctggta
    42121 atcctactcg ttttgcattg gaagaactga ttgctgattt ggaaggcggt gttcgaggat
    42181 tcgctttttc ttctggtctt tctgggattc atgccgtttt ttctcttttt caagctggcg
    42241 atcatatctt attaggagat gatgtctatg gaggaacatt ccgtctattt gacaaagttc
    42301 ttactaaaaa tggtctcgag tacacgatca tagatacgag taatcttgat aaaatagaac
    42361 aatccatcaa acccaataca aaagcacttt atcttgaaac acctagcaat ccgcttctaa
    42421 agattactga tttagaaaaa agtgccactc tggctcatca acatggattg atagttattg
    42481 ctgacaatac atttgctact ccttattttc aaagaccttt agatctcggt tctgatatcg
    42541 ttgtccatag cggtaccaaa tatctaggcg gacacagcga tgtagtagct ggtttagtga
    42601 cttctaacca taaagatcta gccgatcaga tcggatttta ccaaaatgct atcggagccg
    42661 tacttggtcc ccaagatagc tggttacttc agcgcggaat caagacacta agtgttcgta
    42721 tggaggaaca tcaaaaaaat gcttttgtgg tagctgattt tctattttct catccagcag
    42781 tagaaaaggt ctactatcca ggattacccg atcatgaact ccatggagtt gctaagcagc
    42841 agatgagcgg ctttagcgga atgatttctt ttactttaaa aaatgaagaa tctgctattc
    42901 catttgttga atcactccaa ctatttactt tagcagaaag tttaggtggc gtagaaagtt
    42961 tagtggaaat tccttctgtc atgactcatg cgtctattcc aaaagaaaaa cgagaagagg
    43021 ctggcataaa ggacggcttg atccgtcttt ctgtaggaat tgagtatggt caggatctca
    43081 taaacgattt agctcaggca tttgacagaa tcaagaacta gaagtcccaa taaacgactt
    43141 agcagaaaaa tctaaaaaat atttcagatt gctacacctt ggaaacgata agtgttagaa
    43201 tcaagtagaa agacgttttt gtaaatttca ctaaataatt ctttagtgaa aagcatcaaa
    43261 acgaatgaac aaacagatag gagtcttaca aatgagaatg aatgtcgaaa gttttaatct
    43321 tgaccataca aaagtcaaag caccttatgt acgtgtagct gatcgaaaaa cgggtgcgca
    43381 tggcgatgtc atcattaaat acgacgtccg ctttaaacaa ccaaataaag aacacatgga
    43441 catgccaagt ctacattcac ttgagcactt gactgccgaa ctaatccgca atcacgcaga
    43501 ttacatcgta gactggtctc caatgggatg ccaaacaggc ttttacttga ctgtattgaa
    43561 tcatgaaagc tacgaagaca ttttagatgt tcttgaagca acaatgaaag atgttcttga
    43621 agctactgaa gtacctgcaa gcaatgaaac acaatgtggc tgggctgcca gccatacact
    43681 agaaggtgca caagctttgg ctcgtgaatt tttagcaaaa cgcgatgaat ggtctgaagt
    43741 agaagcatag tttctaaaag aacgtaaaga tgagaagcaa tatagctatc ttatcttcgt
    43801 attttattaa atatttattg tctgaaaaga gttctaaacg ggaaaacaaa tagctagttt
    43861 tcagtttagc gctcttttta ttatataaaa tagaaaggag aaaactttat gtctatttat
    43921 aattttgaaa ctactttaga agacggcact gtctattcat tgaaaaaata tgcaggcaaa
    43981 ccgataatca ttgttaacac tgcaacaaaa tgcggtctag cacctcaatt taaacaatta
    44041 gaagaacttt accaagctta tcagacacaa ggtctggtta tcttaggctt tccttccaat
    44101 caatttaaac aagagctaga ttcagcgact gaagcagcag aagcttgtaa aaccacttat
    44161 ggcgttacct tccctatgca tcaattgatt gacgtaaatg gagaaaatac agatcctctt
    44221 tttacttatc ttaaaaatga agctcctggt actgtcacta aagcaataaa atggaatttt
    44281 actaaatttt tgattgatag aaatggcaaa gtaatcgaac gatttgcacc acaaacttct
    44341 ccattgaaaa tgaccgctgc aattgaatcc gttctttaac ttaataaaaa taaaaaaaga
    44401 tgaactattt ctagttcatc tttttgcctt tgcgtggcga cgtcctactc tcacaagggg
    44461 caacccctca ctacaatcgg cgctaagaag cttaacttct gtgttcggca tggttacagg
    44521 tgtatccttc tcgctatcgc caccacactg tggtgttatc ttttattgag taaattttgt
    44581 tcactcaaaa ctggatttga agtca
//
LOCUS       DACGMI010000019        42180 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.019, whole genome shotgun sequence.
ACCESSION   DACGMI010000019 DACGMI010000000
VERSION     DACGMI010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42180
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.019"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(233..1081)
                     /locus_tag="IXT46_001171"
     CDS             complement(233..1081)
                     /locus_tag="IXT46_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4947096.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="IXT46_001172"
     CDS             complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="IXT46_001172"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAQ4947097.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3582..3761)
                     /locus_tag="IXT46_001173"
     CDS             complement(3582..3761)
                     /locus_tag="IXT46_001173"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAQ4947098.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3808..5631)
                     /gene="cadA"
                     /locus_tag="IXT46_001174"
     CDS             complement(3808..5631)
                     /gene="cadA"
                     /locus_tag="IXT46_001174"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAQ4947099.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5909..8188
                     /locus_tag="IXT46_001175"
     CDS             5909..8188
                     /locus_tag="IXT46_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4947100.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8281..8928)
                     /locus_tag="IXT46_001176"
     CDS             complement(8281..8928)
                     /locus_tag="IXT46_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947101.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(9107..9826)
                     /locus_tag="IXT46_001177"
     CDS             complement(9107..9826)
                     /locus_tag="IXT46_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4947102.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9957..11108)
                     /locus_tag="IXT46_001178"
     CDS             complement(9957..11108)
                     /locus_tag="IXT46_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAQ4947103.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11325..12065)
                     /locus_tag="IXT46_001179"
     CDS             complement(11325..12065)
                     /locus_tag="IXT46_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4947104.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(12069..12392)
                     /gene="rsfS"
                     /locus_tag="IXT46_001180"
     CDS             complement(12069..12392)
                     /gene="rsfS"
                     /locus_tag="IXT46_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAQ4947105.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12449..13042)
                     /locus_tag="IXT46_001181"
     CDS             complement(12449..13042)
                     /locus_tag="IXT46_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4947106.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(13026..13673)
                     /locus_tag="IXT46_001182"
     CDS             complement(13026..13673)
                     /locus_tag="IXT46_001182"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAQ4947107.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="IXT46_001183"
     CDS             complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="IXT46_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAQ4947108.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="IXT46_001184"
     CDS             complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="IXT46_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAQ4947109.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(15119..15646)
                     /locus_tag="IXT46_001185"
     CDS             complement(15119..15646)
                     /locus_tag="IXT46_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAQ4947110.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15826..16611)
                     /locus_tag="IXT46_001186"
     CDS             complement(15826..16611)
                     /locus_tag="IXT46_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAQ4947111.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16604..17473)
                     /locus_tag="IXT46_001187"
     CDS             complement(16604..17473)
                     /locus_tag="IXT46_001187"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAQ4947112.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17474..18853)
                     /locus_tag="IXT46_001188"
     CDS             complement(17474..18853)
                     /locus_tag="IXT46_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAQ4947113.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18861..19280)
                     /gene="fabZ"
                     /locus_tag="IXT46_001189"
     CDS             complement(18861..19280)
                     /gene="fabZ"
                     /locus_tag="IXT46_001189"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAQ4947114.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19305..19781)
                     /gene="accB"
                     /locus_tag="IXT46_001190"
     CDS             complement(19305..19781)
                     /gene="accB"
                     /locus_tag="IXT46_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAQ4947115.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19784..21019)
                     /gene="fabF"
                     /locus_tag="IXT46_001191"
     CDS             complement(19784..21019)
                     /gene="fabF"
                     /locus_tag="IXT46_001191"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAQ4947116.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(21038..21775)
                     /gene="fabG"
                     /locus_tag="IXT46_001192"
     CDS             complement(21038..21775)
                     /gene="fabG"
                     /locus_tag="IXT46_001192"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAQ4947117.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21787..22704)
                     /gene="fabD"
                     /locus_tag="IXT46_001193"
     CDS             complement(21787..22704)
                     /gene="fabD"
                     /locus_tag="IXT46_001193"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAQ4947118.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22811..23035)
                     /locus_tag="IXT46_001194"
     CDS             complement(22811..23035)
                     /locus_tag="IXT46_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAQ4947119.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(23088..24050)
                     /locus_tag="IXT46_001195"
     CDS             complement(23088..24050)
                     /locus_tag="IXT46_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAQ4947120.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(24060..24500)
                     /locus_tag="IXT46_001196"
     CDS             complement(24060..24500)
                     /locus_tag="IXT46_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4947121.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24806..25771
                     /locus_tag="IXT46_001197"
     CDS             24806..25771
                     /locus_tag="IXT46_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAQ4947122.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25828..26058)
                     /locus_tag="IXT46_001198"
     CDS             complement(25828..26058)
                     /locus_tag="IXT46_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAQ4947123.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(26144..27031)
                     /locus_tag="IXT46_001199"
     CDS             complement(26144..27031)
                     /locus_tag="IXT46_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAQ4947124.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(27120..28343)
                     /locus_tag="IXT46_001200"
     CDS             complement(27120..28343)
                     /locus_tag="IXT46_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4947125.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28360..29439)
                     /locus_tag="IXT46_001201"
     CDS             complement(28360..29439)
                     /locus_tag="IXT46_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4947126.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            complement(29570..31297)
                     /gene="ptsP"
                     /locus_tag="IXT46_001202"
     CDS             complement(29570..31297)
                     /gene="ptsP"
                     /locus_tag="IXT46_001202"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAQ4947127.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(31297..31563)
                     /locus_tag="IXT46_001203"
     CDS             complement(31297..31563)
                     /locus_tag="IXT46_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAQ4947128.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            32042..34276
                     /locus_tag="IXT46_001204"
     CDS             32042..34276
                     /locus_tag="IXT46_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAQ4947129.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34424..34744
                     /locus_tag="IXT46_001205"
     CDS             34424..34744
                     /locus_tag="IXT46_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAQ4947130.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(34949..35173)
                     /locus_tag="IXT46_001206"
     CDS             complement(34949..35173)
                     /locus_tag="IXT46_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HAQ4947131.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(35371..36951)
                     /locus_tag="IXT46_001207"
     CDS             complement(35371..36951)
                     /locus_tag="IXT46_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAQ4947132.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(37352..38728)
                     /locus_tag="IXT46_001208"
     CDS             complement(37352..38728)
                     /locus_tag="IXT46_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAQ4947133.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(38856..39974)
                     /locus_tag="IXT46_001209"
     CDS             complement(38856..39974)
                     /locus_tag="IXT46_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4947134.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            40116..40550
                     /locus_tag="IXT46_001210"
     CDS             40116..40550
                     /locus_tag="IXT46_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4947135.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(40628..41161)
                     /locus_tag="IXT46_001211"
     CDS             complement(40628..41161)
                     /locus_tag="IXT46_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAQ4947136.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(41255..>42180)
                     /locus_tag="IXT46_001212"
     CDS             complement(41255..>42180)
                     /locus_tag="IXT46_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAQ4947137.1"
                     /translation="WEGLGYYSRARNIQAAAKQIMSEFDGEMPQTPEEISSLKGIGPY
                     TTGAIASIAFGLPEPAVDGNVMRVVSRLFCIEADIAKASSRKIFDEAMRKIIDEKHPG
                     EFNQAMMDLGSAICTPTSPKCETCPIQAFCLANKRGIQTSFPVKTKKAKPKDVYYISA
                     ALQNHSGAYYFEERDSQKLLANMWTFPMMEVTQEEYERLKKEWETKPEIDLFDDLVAE
                     EEQNLPFEKQELFVWQTRHLGEVTHIFSHLKWHVLLFYGRATEGAEQEFTENKTSKWL
                     KPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF"
BASE COUNT        11983 a         9052 c         7296 g        13849 t
ORIGIN      
        1 aagaaaaaat gggcggagca agaaattctt tacctaattt caagataaaa tcaacttttt
       61 gtttcacagc aatcacttaa agttacatat ccaactattt ttttcattaa aaaataaact
      121 tatttttgaa aattatgttt tcttaagtcg tgaaacactt tgatggatca tttatttgtg
      181 gaaaactacg ttttgttatt ctaaaaaact tatataaaaa atagtaaggt ttttatttcg
      241 aatccataaa atattcttgg attgcttctc gtgttttttt cactttttcg ctaagctttt
      301 cgtttttagc catatagaaa taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg
      361 aattagttgc cgcacttcga ttcgtgattt cttttggtct agatgtttgt acgagtacat
      421 cggctatctt gctaagcggg ttatttccaa attgcgtcaa cgcaatgatt tcgatattca
      481 tgcttttcgc cagctcggct aatgcgacta catctgcact tctacctgag tttgaaacaa
      541 gccaaagcac tttctttttc tcattgctga caagttgcgg gagcaagacg tggatatctt
      601 tttcaaaaat gattggctta ccgacacgag accatttttg cagaatatct tctactacta
      661 aagaagaggc gccaacccca tataaaaaaa cagtctctgc cgattccaaa cactctacga
      721 ctttttggat cgtttcttct tctagaatat ctactgtttc ttttatcgct acttgtgcat
      781 tgttaccaag tttgtttttg atagagtaaa aggactcatt tgcttctata tcactaaaac
      841 cttcatcgat tccagtctgt agttctgttg aaatcgtgat tttgaagtcc gtcagacttt
      901 gaaaaccgat ttttttggaa aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg
      961 ctaattcatt agctgtcatt gtagggacct tctcaatatt accgataatg tagttggcca
     1021 actttttttc tgctgaagaa taatcttcca tcatactttc aatacgacta attacgctca
     1081 taagttcctc caccctttta atgatagtct atgtaagtat accatatcag acccttattc
     1141 acggtcgtat actggataaa aaacaaaaaa acaatccgcc caacagaata tcttatccca
     1201 tcaatcccac agattctatt gagcatctgt gtctttgagg aatacctgtt atctattgtt
     1261 cggattgctt tctatctact acttttttac aggaaattta cctattagtt ttctctgctg
     1321 taatttttga cttctgcttc catagcatca ataaagatat tcaaatcttc tacagctgtt
     1381 tctttacttc cataacgacg tacgttcact gttgcatctt ccaattcctt gtctccaaca
     1441 actaattggt aagggatctt ttgtgtttga gaggcacgta tcttatagcc cattttttca
     1501 ttacgatcat caacttctac acgcaacccc ttcatttgca aacgttcttt gatttcataa
     1561 gcataatcgc catgtgcatc aacagaaaca gggatgattg ttgcttgtat aggtgccaac
     1621 catgttggaa aagcgccttt gtatacttct gttaaataag cgacaaaacg ttccattgta
     1681 gaaacaattc cgcggtggat aactactgga cgatgcgtat tttccccgtc ttctccaaca
     1741 tatgtcaaat caaagcgctc tggcaataag aagtctaatt gtatagttga taatgtttct
     1801 tctgtaccaa gagctgtttt gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg
     1861 ccttctgctt caaagtaatc tagttctaat tcatccatag cggctttcag cattgcttgg
     1921 gctttttccc acattgcgtc atcatcaaaa tatttatctg tattgtttgg atcgcgatag
     1981 ctcaagcgga aacgataatc tgtaatattg aagtcagcat atactgccac catcaattca
     2041 agcgtacgtt taaattcatc tttgatttga tcaggacgaa caaatgtatg accatcattc
     2101 aacgtcattt ctcgtacacg ttgtaaacct gacaaagcac ctgatttttc atagcgatgc
     2161 atcattccta attcagcgat acgaattggt aattcacgat aagaatggat cgtgtttttg
     2221 tagaccatca tgtgatgagg gcagttcatt gggcgaagaa caagcatttc gccatctccc
     2281 atatccattg gcgggaacat gtcttcttga taatgatccc agtgtccaga tgttttgtac
     2341 aactcaacat ctcccattat tggtgtatat acatgttggt aacctagact aacttctttg
     2401 tctacgatat aacgttcgat cgtgcgtcgg attgttgccc cttttggaag ccagaatggc
     2461 aaaccagaac ctacttctgg ggaaaccatg aacaagtcaa gttcttttcc tagtttacga
     2521 tggtctcttt cttttgcttc ttcacggaga cggatatatt ctttcaaagc tttcttgtca
     2581 aaaaaggctg tcccgtatac acgttgcatc atttgattgt ttgagtttcc acgccaataa
     2641 gcacctgcca ctgataataa tttaaatact tgtatacggc cagtggatgg aacatgtggt
     2701 ccacgacaca aatcgatgaa ttcgccttgt tgataagcag taatcacttc ttcttctggc
     2761 aattcactaa tcagttctac tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt
     2821 tttgaaagaa cacggcgttc gatcggcaga ttttctttga cgattttcat catttctgct
     2881 tcgattgccg gcaaatcttc tgcagttact tggttttgtc cattatctgt atcgtagtaa
     2941 aaccctgaat cgatagctgg tccaacgcca aagtggatat ttggatagag gcgacgcatg
     3001 gcttgggcca tcaaatgagc tgctgaatga cggactaagc caagtgcatc ttcatggtct
     3061 ggtgtgatga tctcaatact tgcatcttcc tcgattggac gagtcaaatc aacgagtttt
     3121 ccgttcactt taccagctaa agcttttttt gctaagcttt ttgaaatgct ttcagcaatt
     3181 gccaatgttg ttgttccaga ctcaaattct ttgactgcac catctggaaa agtaattttt
     3241 atcataatag tttcctcctt gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa
     3301 aaaaatccta gcatctcttg aaaagagata ctaggacgaa aagttcgtgg ttccacctaa
     3361 tgttcaaacg caaatgcgtt cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca
     3421 agggtttcga aagtggtcat cctttggttt tctcctggaa aagtttcagc ctagcttttc
     3481 ctctcttatc gaagactctc aaattcagtt ggctttctca tcaatcaatt atgtgtttat
     3541 ttaaccacta ataaatagaa aaatcaagtg ggaaactaaa cttatttttt ccattcccca
     3601 tttacaccgt atgttccttt tttcatctca ttgatgatga catggatgtg ttcttttggt
     3661 gcctgcgtgt ttttatgaac agcttccgtg atatctttca tcatattttc taattgttcc
     3721 ggactgcgac cttctactaa ttcgacatgt acgaatggca taatgctctc tcctctttct
     3781 gatcgttctt ttttcaactc gattctatca tactatgttt gtcttgggta ctgaatcagg
     3841 aaaaatggct ggatcttttt ttgctctcaa ggcactcaaa atagagaccg tatccacgac
     3901 ttcttgcaaa acagctccga ataatgcggg gattagtccc gtacttgcaa ttaacatcaa
     3961 aaaaatacaa ataaagatgc caatcagtac agactgtttc gctattctca tcgtatctct
     4021 tgaaatcact actgcttttg ctacacgcaa gagatcatct ttcaagatga ccgcatctgc
     4081 actttcacta gcagctgtag aaccatgagc ccccattgca ataccgatat ctgcagcagc
     4141 aagtgctggt gcgtcattca cgccgtctcc taccatcgca acaggtcttt gatctttagg
     4201 gatactttct aaaatggtca gtttatcttg aggcaagcta cgggcatgta cagaatctaa
     4261 ttggactttt tctgcaatcg tttgagcaat ggcagatcca tccccggtga tcatcatcaa
     4321 atttttcaca tcaagttttc ttagctcctt gattgtcttt gctgcttctg ggcgaatctg
     4381 atccgaaaat aggatcgttc ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt
     4441 ggacgtttct atttcttcag ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt
     4501 attgactact gcttggattc cttgaccggt cacttctttc agttgactaa caggatacag
     4561 ttggctgttt ttcacgttgt tcactaacga acgagctaag atatggctag attcctgttc
     4621 tgcactagct gcatacagaa gtagctcttc tttttttatt ccattgactg gctgaatcgc
     4681 ctctacttcc aatatccctt tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt
     4741 acgtgcgagc ttttcaatcg ttgttccagt ttttacaacg atcccgtttt tacttgaacg
     4801 gctcattcct gcaactaaag caatgggcgc agctagaatc agtggacaag gtgatgccac
     4861 taccagtacc tcagcaaatc gtaaagggtc ttttgagaac caccaagaaa taccaccgat
     4921 caaataagca atcaacgtga aagggactgc ataacgatca gctaaacgga caaatcgggc
     4981 aggcttttct tttgattctt cgactagttt aataatcatt tgatactggc tgtctgcggc
     5041 acgtttttca gcgatcattt ggatcgatcc gtctccattt aaagaccctg acataatctg
     5101 atctccaggt ttcttggttt ccgggcggga ctcacctgtc aaagaagatt catcgaccga
     5161 agattctcct ttggtcactc gaccatctgc gggtacaagt tcgccaggct tgactagtaa
     5221 ctggtcatca atatttattt catcgattac tatatcctgc aattttcctt ctttgaatcg
     5281 atgggcaatt cttggggtgt tatctaacaa agactgcagt tctttacccg ctcgtttatt
     5341 cgcgtaatcc tctagactat ctccgcccgt aagcatgatc aatatcatca aactagccca
     5401 gtattctttg acggctaatg ttgcaaggat tgcggtaatc gctaatacat ctacgccata
     5461 tcttcctgaa cgtaacgtct tgatcatttc caaaaacatc aagaaggcga gaatccctcc
     5521 agtaaatgcg acaatcgcaa atgcaagggc cggctggtga aaaacaaatt cacttaataa
     5581 agctatccca ccaataagca aagtaagtaa aaattttttg aaatgtgtca ttgttttttc
     5641 tcctctttta tgtgacttag agaggttagt aataaatttc cagctgcctc tttcatctta
     5701 agcatagtcc ttgactagca ctttttaaaa caataggcct taattgaaaa caactatcac
     5761 tatcagcgtt tccaaaattc atcagttcta caaacaaaaa tattcagcaa ggattacttt
     5821 ttcgattcat cagttaaaaa gtaccttttt tcgaaaaact atgctatact tttaattcgt
     5881 tatttacggc ggaaggagca aacatgcgat gaatgagaaa caactagaac aaacgcacgt
     5941 ggatgaaacg atcgaactaa tccagatcga acaaaatatg ctggatacaa aacaacaaga
     6001 attgactcag gaaatgaatc attcgacaaa agacacagct aatcacaaga ttcgagctgg
     6061 ttccaatgaa gctttttatg aatctgctgt tgaatatcgc caacatgagc aggaattgct
     6121 tttgaaatac catactcttg aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa
     6181 agatagtcct tattttgccc gtatcgactt taaagaagac cgtgaaacag aaacattata
     6241 tctaggtatc gcttctttaa gagatctggc agaagaaaca atcgttattg actggcgcgc
     6301 accaattgcc aatctttatt atgaaggtga gattggtccc gcattttatg aaactgaaac
     6361 agatagaata gatgtcgatc tgcagttgaa acgacaattt aaaatccaag aaggacgtat
     6421 tttatctatg gtagatacgt cggaagtaat caatgatgac tttttgctag agatattgga
     6481 tgaatcatca agcaaccata tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc
     6541 aatcattcgg gacacaacaa gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa
     6601 gacatccgct ttgcttcaac gtattgcttt tctgttgtat cataatcgca agtggctcga
     6661 ggctgaaaac gttcttctat tttcacccaa ccatttgttt tctgattaca tctcgactgt
     6721 attgccttca ttaggtgaaa gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca
     6781 gctgctgcca gagttttctt tactagatga acagcaacaa gaaagtggtt ttttgctagg
     6841 ggaaaaagat ccgatacaag tgatgaaaag cggattgacc ttagtcgatc agattgatcg
     6901 ctatatccaa ggcatcacaa actacggtcc cttgttccgt gatatgaaaa taaatggccg
     6961 tacgatccta tcaaaggaat cgattcgcca atggtataaa gaaacaaatg aacaattacc
     7021 tttacatcat agactttctc tattacaaac gaagctcctg aaaaaattag gcggtctgca
     7081 aaaagacgaa acacgtcagc aatgggtcaa agatctggcg gaagaacagc tccaagaact
     7141 atacgcaaca gatccaaatc ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa
     7201 actggccaac caaatcgtac gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta
     7261 tcaatttgtc aatataacga aacaatatct ccactttcta caaactgtgc cactttctct
     7321 tctaacacga cataaaatca gcgagaccag gtggcaggaa catttgacaa ctgttcgtac
     7381 acacttgcgt caaagagaat tgcgtcaaga ggatgctgta ctattctttt tactgatgcg
     7441 ccgaacatat ccagtgacgg ttacacacaa agctcgctat atctttattg atgaaatgca
     7501 ggatttcgca ccatcacaag tggcattgct gcaagccttg ttcccaaaag caaatttgac
     7561 tttctgtgga gatctaaatc aaaatgtctt tggaaatgaa acgatcgttg gatcattgga
     7621 agaccttttc gtggaccgtg aagtcactcg tttccaatta acgacaagct atcgctccac
     7681 aaaagaaatc actgattttg ctaatcattt tattgtgaaa gaacatcaag tagaaacaac
     7741 agcaagaaaa ggagaccttc ctttgctcat ccaaggaaca acagatgata tcaaattgaa
     7801 ttggttagca gataccattc gaacgactca gggaaaagcc cggtattggc gtacagcaat
     7861 catagctaaa acacaagaag aatgcgaagc tctttatgct caactgccag acgagttgaa
     7921 acaacaagtc cagctgattt taaatgagag tgactttatg aagcgttcca ttattttact
     7981 tccagccttt ttagcaaaag gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc
     8041 agaacatttt tcttctcagc aagacaaatt gatcctttac accatgtgta cacgtgcgat
     8101 gcatgaattg acccttttta cctccaataa tgaaagtcct ttgttaaaca atatggatat
     8161 ttcatcttat gagaaaaaag tactgtaagt aaaaagacaa ctgctatcat taatgttagc
     8221 agttgtcttt ttatttacaa taataattgc agaaaaagta attcaatcat ttaaggtcat
     8281 ttattctata tataaatcca aatctgtttc aggatatttt aatttgacaa gcgaaataat
     8341 cattttcagt tcttccatgt tttctggata ttctgggtca aataccttgc tatgacggcc
     8401 aatcccgcca ttgtcgatca atcggtaaat tcgattccat tcaatgaatt ggtcaattga
     8461 ttggaaattg ctgattggat agccgccaca atccaaaatc tctgatacac gaaatgctag
     8521 gtatgcacta tcgatcactt tatttttttt cgtgtctatc ttctcatttc tttcgataag
     8581 aattttttca ggacgatgtt tcaagctcca ctctaatagt agaaagaaag cctccatccg
     8641 atactcttct tcaaataacc gaaaggctga atcagaacga cgaaaaagca gcggaatcag
     8701 ataattttgt ctataaatca gcattggtgc gcggtccacc atacactcta aataacggtt
     8761 cagataccct gtaccgacat agtttcctaa tcgatagcct tcaacgccga atcttgcgta
     8821 tttttgcgct aattttgaac aatcagttac gttcacagct aactcttcta ctttgcggta
     8881 accgcttaag atacgttcaa aaggttctaa agtgattttt gcttccatat tcttccccgt
     8941 ccatcttcca catacttcat atcatttcac atgatactta tgctctcatc ataccacagg
     9001 ttgaattaga aaagaaaata aatcacacaa aaaagcaaga caatctgtta gtgagattgt
     9061 cttgcttttc gaaaaagact gaatactttt cgttaaaact ggttgcttag tcttctaatg
     9121 ccacattatg gaacacatgc tgtacatctt ctagatcttc cagtgcatca atcatttttt
     9181 caaatgtttc ttgatcttct ggagatagtg ttacctcgtt ttgagggatc atttggatct
     9241 cagcgattga aaaatcagtg attccttttt cttttaatgc ttcttgtata ctatggaaat
     9301 ccgctacttc accgtaaacg atgatttgtc cttcttcttc cattacatcg cgaacatcga
     9361 tgtctttttc cattaggtat tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga
     9421 ttgctgtatt gtcaaacatg taagaaaccg ctccggaaac acccatgttc ccgccatttt
     9481 tcccaaatgc tgcccgtacg tctgctgctg ttcgattcac attgttcgtc aatgtatcaa
     9541 caatcaccat tgagccgctt ggtccaaatc cttcatagcg caattcagag tatgtttcat
     9601 ctcctgcacc ttttgctttt tcgattgctc ggtcaataat atgttttggt acattataag
     9661 ttttagcgcg atcaatgacg aaacgtagtt tttggtttgc atgcggatca ggatcacctg
     9721 attttgctgc cgcgtagatt tcaatcccaa attttgcata aatccggcta ttattagcat
     9781 ctttagcagt tttctttgct acgatatttg cccatttacg tcccatattt tcacttcgct
     9841 ttctgatttg atagtttcat aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg
     9901 attctgtgaa gctttttttc tttcttcctt cattcttctc atttttagtc aattatctat
     9961 actcggattg ggatttgccc gaaattctgt tccggaatat tgcctcccaa ttgatagatt
    10021 tgatcacttc taactaacag ttccgcttct tgtgcctctt tttttccgat tcgggaataa
    10081 atagaaatct cttttttttc ttttaagaat cttcttccag catcggtaaa tccaagtagt
    10141 cgaagataat ttttattttg ttggacagga atctcttgct ttttgatatt cagcaagaca
    10201 taacaagata atcgttggat ccgtgtccat gtatatcttt ttgtttttac ctttgacaca
    10261 aaatcctcaa aactatcagc agttgcagct gctgttttca tgcgcgattc tattccttcg
    10321 gtcatctgat agatatctgt cagttccagc aaagtagaag ataacaaccg ataacgcaaa
    10381 tacggccaat aagattccca agtctgcagc gaacaagttg aaagatcttc ttctgtctga
    10441 ggcggcacaa gtccagctat tctttttcct tcttctaacg catggcgaat ggctgttgca
    10501 ctggctatcc tctgatctgt gatgattttt tcatgatagc ctgcactttt acgtcggatc
    10561 ggatgtaatt ccatagggtg gacatacttg gcattttcct ttgcataact taatcccaag
    10621 atatgatttg gcgaagaaaa atcaagcgta atatcgggat acagactgcg aaaaacctca
    10681 gtcatttttt gcggataact atacgtttga tcagacagtt cttgaaatgc ctcttctatc
    10741 ctatcttgat tctcttggac aaagcgtccg aaactgctgt aatcaaacga agtctcttct
    10801 tctgttccaa aacacaaact gtcacagtcc agtgtttgca agatttttac tgcaccttta
    10861 gcaaaatagt cagctgactg aaccgcccat tcgacgggaa gctccactac taaatccaca
    10921 ccattttgta aagcttcatt cgcgcgatgc catttatcga tgatagccgg ttcgcctctt
    10981 tgcaaaaaat tcccgctcat tacagcaatg acgacctctg ctcctgttat ttttcgtgcc
    11041 atttccacat gatagcgatg tccattgtga aaaggattgt actctacgat aatcccgcag
    11101 cttttcatgc gcatcctcct tcatagttat cgataaaaaa gaaatagaga caagtaaaaa
    11161 aaggcaaaaa tcggaaaaaa tacccgaact atataaacta ttctcgcaaa cacaatactt
    11221 ctgcgacgaa aagctgcact gcaagagcaa tgcctatatc gttcggatat ataatttatg
    11281 ttgaagattt attcttttct tgttaactcg agcaggcaaa accgctagtc tttgtatgct
    11341 acaaagaacc agcgctttga tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct
    11401 tcgactttcg aaaagccgct gttttccagc attcttaaat aactttccaa tggataggta
    11461 cgctcttgat gtagttcatc ttcacgaata aatcgaccag acccttcttg ttcttcaacg
    11521 aaaaaggtaa gaaaatgttc gatgctgtgt ttctcgcttc ctggataact atcccacaaa
    11581 aaagcaaaat tatccccttg ataatgatag ctatattctg gaaaaacctc atctacttga
    11641 taggtggagt gtacgtcaaa taaaaatcgg ccattttctt ctaacgcttg atagacttca
    11701 tcaaacactt gctgtacctc ttgtctattt ttcatatagc acagcgaatc agaaaaacag
    11761 gtaattgcct gatattgtcc gatttctgat aaatcgagca tattgccttc cacaaattgg
    11821 atcgatgcgt cttcttcata tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg
    11881 tctaaccctg tcactttata tccatctttt gcaaaggcaa ccgctaatgc tccagtaccg
    11941 catgccagtt ccaaaatatt ttttgtgtct tcttgtaaat gacgtttcga aaaagctaac
    12001 cattgctgat aaagtgtttc gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa
    12061 gccatatgtt aatccaacca ttcactaaga tcgactagcg gagcatctga ccatagtttt
    12121 tccagattat agaaatttcg ttctggcgca tggaaaacat gtacgatcac atctccaaga
    12181 tcgatcaata cccattttcc gccttctttt ccttcaatac gttttacttc atatttgttt
    12241 tcttcttctt tatcaatgat ttcttctgta attgcgttga tttgacgttc gctatttgct
    12301 gaacagatca tgaaataatc tgccaacaag gaaacatttc gaacgtctaa agcgataatg
    12361 tcttctgccc gttttgaatc tgctgcttca atcgcaattt ttaattgttc tttactatct
    12421 atgatgattt cctcctaata tgagcagctt atttttttgc tacccagtaa ttatatgttt
    12481 cgattgtttt tggataaatc tgttgttctt gcgcaagcaa atgggccaat gtatgttttg
    12541 tttcaaatgc tacagcttcg tctagatcag cccatgcaat ggctcgtgca tcttgtaccc
    12601 caggaaaatc tcgacctggt tcaatatagt ctgctacata aatgattttg tcaaggagac
    12661 tcatcttagc agccccagtc gtatgcaccc ggattgcatg aagaatctct gcatcggtga
    12721 ttcctaattc ccgctctaca aacgaagcgc caacaagacc atgccagatt gcattattat
    12781 aattcaataa ctccggatca aaaccgtctc ttacgattac cattttgaac tcctcatctg
    12841 gtcgttcttt tgcataatca tgtgtcaatg cagcaatact agctttttca ggagaagcac
    12901 cgtatttttt ggcaagagcc acggctgttt cttctactcc aagcacatgc ttgaagcgtt
    12961 gttcgctcat tctcatctgt attttttgca tcaggttttc tctagaataa gcagtatatt
    13021 cattactata gtccatattc atacaaccct tcattttgaa tataatcaat tactttatct
    13081 ggaacaaggt agcggataga acagccttct ttgatctttt gacgtatttt cgtggaactg
    13141 atgtcgatct caggtacatc tacccaaatt acaggatatg gagtatccgt tgtgtatcct
    13201 ggtcgacgta tacccacaaa gttgaccata gaagtcagct catcgatttt ataccatttt
    13261 ggcaaatatt ctaccatatc cccaccgata ataaagtaat aatctgtatc cggattgttt
    13321 tgcgtcaatt ccttcatagt atcataggtg taacttttcc caccacgagc taattcaatc
    13381 gtttcaatct gcaaaaaagg attgtcttcc accgctaatt ccaacatgtt gagtcgatgt
    13441 tttgcatcaa tcgtctgttt ctcatcaaca tgaggtggct gataagaagg catcaaaaat
    13501 acgcggtcaa gacctaaatt ccggccagct tgttcagcca tcactaaatg tgcaaggtga
    13561 acgggattga atgttccgcc caagatccct acttgctttt tcttctctaa gaattgaggc
    13621 atttcttcag gaaataattg tgaacgaaca aatgtcttag cttgcgtatt catcatggtc
    13681 actccttata ttgcttttac ttcttttgat agcctttgat acttttcttt tgtggaaggt
    13741 ttgtataata caataacacg tccaatgatt tggacgattt cgcaatctat ttctttttct
    13801 aatacttgag ctgcttcttc tgcaatctca tctgtatttt gaagtaacga tactttgatc
    13861 agttctcttt tttctaaagc ttcttcaatt tgaacgatca ttgctgaatt gatcccacct
    13921 tttccgattt gaaaaatcgg ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt
    13981 tttcctctta aactcataat tttccttctt ccttaaatca atgctttgcg tttcaataca
    14041 tctacaccct ttggcgccca gcccgcaatt actactggcg ctgttacagt gatccagcct
    14101 agaccggcaa aaacgatgtc tgttttttct ttcacagaaa actcaaaacg aacaagctcc
    14161 ggaaatgcct cgacttcatc aggacgagga ggctgtaata atccacctac atgtttttga
    14221 taaaattcgt ctgctttttc cagtttcgtt cgatgaatat ttacatcatt tgacacataa
    14281 gcaataaatg aagcacgatt gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa
    14341 agtgtttgcc cttcattcag ctgataaact ttaggtttga tttcttttaa cggtgcaatg
    14401 atccgcaaat cttttttacc taagtagtgc gccatttgat ggcgatggat aattcccggt
    14461 gtatcaatca aaaaatgccc gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct
    14521 ggaaactgcg aagttgtgat tacatcttgt actcccgctg tatttttgat gatttgattg
    14581 ataagcgtcg attttccgac atttgttact ccgacgatat agacatcccg tccatcgcgg
    14641 tattcttcga ttttttctaa tagttccgtc atctcatgag atttcttagc actagttaat
    14701 aatacatcta ctggacgaat tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat
    14761 ttagtttttt tcaatgattt aggtaatata tccactttgt tcccaactaa aagtactgga
    14821 ttgtcaccga caaaacggtg tagtcctggg attagtgaac cattgaagtc aaaaatatcc
    14881 accacattga cgatcaatgc atctttttgc cctaattcat tcagtaagcg caaaaagtcg
    14941 tcatccgtca atgagacatc ttggatctca ttataatggc gtaatctgaa acaacgctga
    15001 caatagactt ccccggaagc taaacctttt tccaaagccg tttgcggcgt gtatcctaat
    15061 tcaccgggtt tgtttgtttg tataacggca ccacagccga tacattgtaa ttcttctgtc
    15121 attcgattcc acctcgccag cccatatcag ggtgttttgc taatagatag gccataattc
    15181 ttttttccca aaaacgatta aattgtgtct tccaactatc tgttgcgata atgggtttta
    15241 caaggatgct acgtatccct gcacgattgg ctccacgtat atcagtcata atctgatcgc
    15301 ctaccattac tatctcatca tctgctaaat ccaattgttt ctttgctatg ttgatccctc
    15361 ttgctaaagg tttcattgct cgtgcaacat acaaaagatc aaatttttca atcgctcgcg
    15421 cgacacgttt tgaattattg tttgaaacaa caacaacagg gattcctgca tttttcattt
    15481 ctaaaatcca agtaagcaac tcttctgttc catctggatt attccatgca atcaacgtat
    15541 tgtctaaatc ggtcaatact gctttgatgc ctagattctt taattgggca ggtgtaatct
    15601 gatagatggc ttctaccatc catgttggtt tgtaatttga aaacatgctg tctcctcatc
    15661 tgcaaaaaat gaaggagcac ataaagtact cctcaacccc gtattatact gcatatcagc
    15721 aaaaaaaact acctctatac tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac
    15781 caaaaataaa gattgatcac agaaaaattt agaaacaaaa aacaactaat attggcggaa
    15841 cctcttgtat cgtttttcca gtaatttatg ctgatctaat cgaacaagtt ccgtcaatct
    15901 ttcaatcaac gcttttttca taatgtgtgc gactttatat cgtggcaact gctcgccgtt
    15961 gaacgtttca ggaataactc gatcaacgat tcctaactcg cgtagttctg gcgcagtaat
    16021 tttcatcaac tcagctgctt ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa
    16081 tccttctgga gaaagcacag cataaatcgt ttcttccagc atccagactt catccgctaa
    16141 acctagagca agggcaccgc cacttccacc ttcaccaatg atgatggcga tgatcggtac
    16201 ctttaaatca gacatttcga gcagatttct ggcaatagcc tctccttcgc cgcgctcttc
    16261 tgctcctaca ccgcaatatg cacctgctgt attgatcaag gtaatcaccg gtctattgaa
    16321 cttttccgct tgtttcatca gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc
    16381 aaaatttctg cggatatttt cctgcagatc ccgtcctttt tgaataccga tcactgttac
    16441 cggtttgcca tctaatcgag cgattccacc aacaatcgct tcgtcatctg caaataaacg
    16501 atcaccatgg cattcctcga aagaatcgaa gatctcttca aaaaaatcca agcttgtcca
    16561 tcgttcttta gctcttgcta actgaacgac atcatgtgct gtcttatcca cgatctatcc
    16621 atcctttctg tgtatgcaat tcaagaagcg tatggatttt ctgtttcaat tccatgcggg
    16681 gaacaatctg atcgacaaaa ccatgagata ataagaattc agccttttgg aaatcttctg
    16741 gaagttcctg cttgatcgtc tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt
    16801 ggggttctgc tagaataata tcgccttcca ttgcaaaact ggcagttact cctccggtcg
    16861 tcgggtccgt taaaacagtt agataaaaaa gaccttcatt gctatgccgt ttgacagcag
    16921 cagagatttt tgccatctgc attagagaaa agattccttc ttgcatccgt gcgccacctg
    16981 aagctgtgaa caagacgact ggaagacttt cctttgttgc tcgttcgaat aatctggtga
    17041 tcttttctcc gacaatcgtt cccatacttc ccatgataaa attaggatcc atcactccaa
    17101 taatgaaggg aatcccctga atggttgctt taccagtgag gactgcttca tgaagtcctg
    17161 ttttatcttg cattttttta attttttccg tatattcggg aaatgctagc ggatctttgg
    17221 ttacaagatc cgtatcccat tcttcaaaac ttttttcatc aataatcaaa gctagacgct
    17281 gccatgcacc gattcgaaaa gcgtatccgc aatgagggca tactttttct tcaccgatgt
    17341 ctttcgtata aaggatatgt ttgcaatttg gacactttgc ccacatgtta tcaggaacag
    17401 atggcgagtt agcaggtttg ctctctctat taggattgat ccgaatatat ttctttttct
    17461 taaacagagc catctatgcg cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt
    17521 cttcttgtaa aaatgctgtg ctgtaatcac ctgctatgac tgcaggatga ctaatcaaat
    17581 ccatctgaaa ttctgcgttc gtgatgattc cttctgtgat aaattcactt aaggctcgct
    17641 gcatcttcat taatgcttca aaacgcgtat ttccatggac gattattttt gcaatcattg
    17701 aatcataata tggcgggatc gtatatcccg ggtaaactgc actgtctact cgcagtccca
    17761 tcccacctgc tggaagcagt aagttttgga tcttccctgg agaaggagca aaatggaaag
    17821 caggattttc tgcattaatc cggcattcga ttgcgtgtcc ttggaatact acttcttctt
    17881 gacacacatt caaaggctca ccggctgcta tctccacctg tttttttact aaatcgattc
    17941 ctgtgaccat ttctgttact ggatgttcca cttggattcg agtattcatt tccatgaaat
    18001 aaaaatcgcc ttcttcatcc atcagaaact cgatcgttcc ggcattttca taattgactg
    18061 ctttagctgc tcgaacagca gcgtctccta gtgcttctct ttttgtttgt gagatcacta
    18121 cagaaggaga ttcttccagt actttttgat tgttgcgttg taaagaacaa tctcgctcgc
    18181 ctaaatgaat gacatgacca aatcgatcac ctaagatctg aacttctata tggcgagcag
    18241 gataaatgat tttttccaaa tacatatcat catttccaaa tgccgctgct gcttcttgct
    18301 gagctgaaga aaaatgctgt gggagctctt cttttgattg aactttccga atgcctttcc
    18361 cgccaccacc tgcagctgct ttcagcatca ctggataacc aattctgtct gctatttcca
    18421 atgcttcttc tactgtagat aatacaccag tacttcctgg aatgactggg acatttgctt
    18481 cttgcatcaa ttgacgcgca ttgatcttat ttcccattgc atcgatcgtt gcacttttag
    18541 gaccaataaa tgtgatattg cactcttcac acatggaggc aaatcggcta ttttcagata
    18601 aaaaaccaaa tcctggatga attgcttcgg cttttgtcac gattgcagcg ctcagtactt
    18661 cctgaacatt cagatatgaa tcaacggctt ttgccgggcc aatgcagatt gcttcatctg
    18721 ctaactgtgt atgaagtgct tcggcatctg cttctgaata tatcgctacg gtttggatcc
    18781 ctagttcgcg gcatgcacga atgatacgta cagcgatttc accgcggtta gctatcaata
    18841 ctttagaaaa catatttcac ctatccaatc ataaaggtta attccgcttc ggctactttt
    18901 ttaccgtcta ctttagcgat tcctttgcct attccggctg aagctttcac tttcaatatc
    18961 tcaacttcaa ggtataaggt atctcccggt gtaactttct tacggaattt tgctttgtcc
    19021 aatccgccga aataagccgt ctttcccttg aattgttcaa gagaaagtaa tgcaactgct
    19081 cctgcttgag ccattgcttc aacaatcaat acccctggca taacaggttc ttctggaaaa
    19141 tgtccttgaa aaaagggctc attgatcgtt acatttttct tagcaacgat ccgttctcct
    19201 tcaaccattt cttccactcg atcaatcaaa agcattggat aacgatgtgg aatgatttct
    19261 tttatttctt gtatgttcat tgttttccct ctttcctgct ttgcttattt ttgctgaatc
    19321 ctaaagagtg gctgtccata ttcgacaact gactcgtttt ctacaaggat ttctgtgatc
    19381 actccgtcgg cctcactagt tatctcattc atcagtttca tcgcttcaat aatgcagata
    19441 acttctcctt tggcaacttg atcacctact tttttgaaag ctggtttgtc gggcgctggt
    19501 tgcagataaa cgattcccac gattggcgaa acaacctcga ttccatcaaa tactgccgat
    19561 tctttttctt tcattatttc tggagcagtt gttgcttgtt cagatatgac attgactggc
    19621 tccgaaactg gcaacgtttc gtttgtttga accatattca tgcctcgact tgttttattt
    19681 ttattcatat acaattcaaa ttgaccttca cgcaaatcga attccgttag cgaggattga
    19741 tcaaattgac tgactaattc tctgatttca ttgatatcca aaattattcc tcccagcgtt
    19801 tcatgcacag aaccgcatta tgtccgccaa accctaatga attactcatt gcataagtaa
    19861 aacttgcagg tttgctttcg tttttgacaa ctgtcaagtc aatctcagga tcttgttttt
    19921 ctacattgat cgtaggtggg ataaattgat gttctaatgc cagcaaagtt gccaaggctt
    19981 cgatcccgcc ggctgctccc aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag
    20041 tatctctgaa attttcacct aatgcgattt ggattgcttt tgcttctgcc tggtcattgg
    20101 ctggtgtact tgttccgtga gcattgatat atccgacttg ttccggctgt acaccagctt
    20161 cttccatcgc aagcttcatt gctttagatg caccagaacc atctggagta ggagctgtca
    20221 tatggtaagc gtcacagttt gcaccgtatc caacgatttc tccatagatt ttggcaccgc
    20281 gagcttgtgc atgttctaaa gattcaagaa ctagaacgcc tgctccttca cccatcacaa
    20341 aaccattccg attttcgtca aacggaatcg aaccacgatt aggatcagtt gattctgaga
    20401 gtgctgttaa agctgcaaat ccagcaatcc ccatctcaca aatcgttgct tctgttcctc
    20461 cagcaagaat gacatcagaa tagccatgtt tgatgttacg gaatgcttcc ccaattgaat
    20521 tcgttccgct agcacaagct gttacgatag ctgtacaaat accttttgca cctacacgca
    20581 aagcaatatt tccagctgcc atgttggcaa tcgccattgg tacgaacatt ggagaaactc
    20641 gttttgcacc tttttcatgt agacgaataa cttggttttc gattgttgga agaccaccga
    20701 tcccagatcc gatgatgacg ccaaaccggt cttgattcat tttttcttta tctaaaccgc
    20761 tcatctccat tgcttctaaa gcagcgtaga ttccatagat cgaaaacata tccattcgtt
    20821 tgctatcttt tttaataaaa tatttatcgt aagggaaatc tttgacttca cccgctaagg
    20881 taatccctgt ttctgaagca tcaaatttag tgatcggtgc gatgccattc gtcccctctt
    20941 ttaagctatt caaaaagctg tctgcgtcat ttccaatagg tgaagtgact ccatagccag
    21001 taattaccac tcgattcatt tgtttgctct ccttttctta tccgtgcatg accaatccgc
    21061 catcgacatt gatgacttgt ccggtgatat atggattttg tgctaagaaa actgctgttt
    21121 gtgcaatatc ttctacttgt ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct
    21181 tgactttgtc tgctaaaact tccgtcatat cagttgtgat gaatcctggc gcaatggcat
    21241 tacatgtaat gcctctagtt gcagcttctc gtgccacaga ttttgttaat cctactacgc
    21301 cagctttact agctgcataa tttgcttgac caatatttcc aatcaaccca gatacactag
    21361 agagattaat gatggcccct tctcgctgct tcatcatttt tttcaatacg tgctgcgtca
    21421 tattgaaggt tccaatcaaa ttgatatcca gacatttttt gaaatcttct gcatccattc
    21481 gcatcacaag tttgtcattt gtgattccgg cattgtttac taacacatgg atcgatccaa
    21541 gcttttcttc tgcttctttg atcatttgtc ccgctttctc ataatcagag atgtcaccgg
    21601 aaactcctac gcattttaca ccgaatgctt cgatttcttc tatcttttct tttggaatct
    21661 ctccgcgacc attcaaaatg atatttgctc cagcttttgc aaaagctaag gccatcgctt
    21721 tgccgattcc tcttgtacta cctgtgataa atacattttt tccttttaca tccataacgt
    21781 tcctccttat agtattgcta ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac
    21841 tggtattgtt ttatcgattt ttttcataaa tccgcttaat acttttccgg ggccgacttc
    21901 gatgacttgt tcgatgccga ttgtttttaa cttatggata ctctcataga aacgaacagg
    21961 ttgcatgact tgctgttcaa gtagtcccgc gattgtttct ttcttcatta tttccgttgt
    22021 tgtgttgctt atgataggaa aagaaggttc agagaattga atctgactta ggtccttcgc
    22081 cagttttttt gctgccggtt ctaaaatagc tgtatgaaaa ggcccgctga catttagagg
    22141 gatcattctt ttgaaccctt tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc
    22201 ttcgccacca atcacgatct gctgaggtgt attataattt gcaggagata cgatgccgta
    22261 cttgctagct tcatgacagc tttcctcgat cgtttcaatc ggcgcattca tcactgcaac
    22321 cattttcccg cttccagctg gggtagcttc tgtcatataa gcgcctcttt ttgctactaa
    22381 cgcaactgct tcagtgaagg atagcgcatt actagctact aatgccgaat attctcctaa
    22441 actcagtcct aaagctgcat ctgggatgat tccatgctcc ttcaataagc gataatacgc
    22501 gatgctgact gttagaatag ctggctgtgt atattgcgtc tgatccaaac gttcattttc
    22561 tgtaaagcaa agttcagcca tatcgtagcc gagaatctca cttgcttcat caaatgtctg
    22621 ctttacaacg gcttcttcat ataaatcttt tcccatacct tgatattgtg caccttggcc
    22681 actaaataag aatgctgttt tcatgttttt ctccaatata tccagaatat atgtttgatt
    22741 cttcctattc aaaaaggccg agacattcct atttcaggaa atgtcccagc ccccaaccta
    22801 attttaatga ttatgcagtt tgtttttcta cgtaagtcac taaatcttga accgttttga
    22861 ttccgtcttc tgtttcgatt ttcacgtcaa attcatcttc aatttcattg atgatttgga
    22921 ataaatccaa gctgtcagct tctaagtctt cttggatgtc agtagtcaat ttgatttctt
    22981 cagtttcttt tcctaattct tctgcgatga tttcttgaat tttttcgaat accataataa
    23041 tatattcctc cgatattgtt tgctttttat ttttataatt taacagtcta caactccatg
    23101 agaatacttc cccatgttaa acctccgcca tagcctgtaa atattacttt ctgctgtttt
    23161 cctaaggtga tctttccact agaaactgct tcatccaata agatagggat gcttgcagca
    23221 gatgtattcc catatttatc catattggtc aggaactttt cttgcggcat ctttactttt
    23281 cgggcaattt tctcaataat tctgaggttt gcctgatgca aaagcagata atcaactggt
    23341 ttgtctttca tgacttcttg gatattgttt gcaacgtctc gtacggcaaa atcaaaaata
    23401 tctctgccag tcatttgcaa ataatacgaa ccttctgaat cttctgaata gaacggattt
    23461 ttattttgct ggtagccagc ggtcaatgag ctacttctgg taccgtcagc tgctaatttt
    23521 tctttcagca attttttctg tggattcgct tctaagagaa tcccacctgc tccatcgcca
    23581 aacaacacag cagtcgtacg atcagaccaa tcgattagct tagatagtgt ttcaccacca
    23641 atcaccagtc ccttagttga gccgcagcgg atcatttttt cagccatgct taacgcataa
    23701 acaaatcctg agcacgcagc actgatatca aaagcgatag catgagttgc tcccaatttc
    23761 ccttgtactt gtgctgctac agatggtgtc gtgtaatcgg gcgacattgt tgctactaaa
    23821 ataaaatcca aatctttagg gtttagattt ttctgtttta tcaatttttc cgccactaaa
    23881 atgcataaat cagaagtctc ctgatttgtt acacatcttc gttcacgaat acccgtcctt
    23941 gacgaaatcc attcatcaga ggtatccatc atcttggaaa gatcattatt agtaataatc
    24001 ttttcaggaa ggacgctggc tgttgcagta atcattccaa attgttccat taaatatcct
    24061 cacttatagt cttgcaagaa gtcgtgcaag tttttcagtg catccagcaa ggcatgctgt
    24121 tcctccgtag ccattccgtc taagatgttc ttgaccattt cacgatgaaa atgctgatgg
    24181 acccgaaata gtaactttcc ttttttcgtt agtcccaact ttacaacgcg gcggtcatct
    24241 tcactgcgga tacgttcgac atagcctttt tttactaact tgttaatagc agtggtcaag
    24301 gtcccaacag taattgatag ttctttggct acttctgaag ttgttttttt cttgtacatc
    24361 ccgattgcct cgatcgtgtg catctctgtg attgacagat ctttgaattg agattttttc
    24421 agctcagact cttcgattgt caaaatatca ttgaagacac taacaagata atcatttact
    24481 gtttttaaat ctggttccat gttccaccgt ccactaatta gtttgattat caaatctttt
    24541 gatgttcaaa ctatatctta acttttttca aaatgcaacc ttaaaagatc atttttttac
    24601 tatatgagct ttttttaaga ttttactcat ttaaaacaac tgataaatca gcatttataa
    24661 tttcttttat tagaaaaatc atctatctca catattttga ttatcaaagt attttctgtg
    24721 aacagaacta tagaattccc taaaacttgt ccattatttc aaaatttgtt atagtctttt
    24781 tattcaaagc gtaaaaggag atcctatgtt aaaagaaaaa atgaaaactc tccccatgct
    24841 gccgggtgtc tatcttatga aagaccgaga tggtaaggtc atctatgttg gtaaagcaaa
    24901 acggctcaaa aatagagtaa gcagctattt tcatcagaat aaacagcatt caaaaaaagt
    24961 attacgtatg attcatcata taacagattt tgatttcgtc gtagtagaca cggaattaga
    25021 tgctttattg ctcgagtgtc aattgatcca acattaccgt cctttttata accgacaaat
    25081 gaattatttc agtaattata attatgtaca tattaccaat aagggatttg tattaacaga
    25141 tactcctacg gctcgaacat acgggccttt tcgtctctat aaaaaaatgc cgtctatttt
    25201 gcgtataatg gaagaaactt atcaaatgcc ttggttgtct gaaattagtt tgttagcttt
    25261 gcgagtccag cttcctgacc tacaggaaat gacttttgaa cagaaaaaaa aggaactcca
    25321 agggctgttt caaggccgaa ataaaaagct actgacttac ttgaaaaaaa gacaacaaca
    25381 tttcatctat cagttgaatt tcgaaaaagc cggtatgctt caaaaagata tcgaattagt
    25441 tacttatttt attagacgga tccaggaaca aaagcagttt ttaagaacac catcgctcac
    25501 cttcagcatg ccattagcag cagatgagag tcagaaaaag cactacctcg tttgttatgg
    25561 tcaacttgca gaaacaatga ttacctctgg tgacgtttct cctgacttct attatgaaaa
    25621 gaaagaagct catttatctt tgaaacgtca attgtcaaaa gaagaaatcg atcctgtaca
    25681 aatcttgatc agttaccgca aaaaattaga aaaagaacag tttgaaattg aactgttaaa
    25741 caaaaaagaa gctgaaaagc aactaaatta gttgcttctc ggcttctttt aggcatcttc
    25801 aacttcaaat gtcaattatc ctaaaattta ttggattaag tcatagattt ccatcgctac
    25861 gatatcgata ttatcaaatt cgtattgctg atgagtatct gtttcagtta attcaaatgt
    25921 atcggtcgct ttatcataag ttactgtaca cttctctacg ccttcttttt caaaacggcg
    25981 aacttgcagt tcattatctg ctgactcgac catagcctcc agtcgtttta tgattgcgac
    26041 taattgtgaa tgtgtcatcg gaggtcctcc ttttcttatt tctgttatat tgtatcaaaa
    26101 gcatagccta cttgcattga ttttctctaa aaaaactcgt tttttatgat tttttttctg
    26161 gtatttttcc ttcaggccac caaagtttga tcaaagcttg ggttccgtca ttctcaaaac
    26221 ctttatctgc caactcttca tatagtttca atgcttgggt agttgctggc aatacaagat
    26281 ccattttttc tgcttcttct aatgcaatct ttaaatcttt gataaaatgt ttgacaaaaa
    26341 aaccaggtgt gtaatcttct tttaaaatac gaggagaata attgcttaaa gaccagttag
    26401 ctgcacttcc acctgaaagc gtctcaatca ctttctttaa atcaagtccg tttttttgtg
    26461 catagacaag catttccgtc attcctgtca tcgtacctgc aatcatgatc tgattagcca
    26521 tttttgtatg ctgacctttc ccagcagaac catgcaatgt aaatgtcgta ccaaattctt
    26581 tgaataaagg cagtacttga tcataaacgg cttcttctcc accgaccatg atcgtcagtg
    26641 taccattctt tgctcctaag tcaccaccgg ataccggtgc atctaacgca tctgcgcctt
    26701 tttcttttgc tgtttttgca attttttctg ccaggcttgg tgtacttgta gtcaaatcaa
    26761 ctaaaatatg tcctgagata tctgcagaaa aaatccccga ctgtccatag tagatttctt
    26821 ctacatcttt ggggtaacct accattgtaa agagaatatt actttgttct gctaccgctt
    26881 ttggtgtatc tgcccagata gctccttctg ttactaaagg atcagctttt gcttttgtcc
    26941 gattatagac agctacttcg tgtcctgctt ctagtagatg gcgtgcgaca gcacttccca
    27001 tgacgcctgt tccgataaaa ccaagtttca ttttttcgac ctcctaaaaa tcaaaaatcc
    27061 ttgcttctat gctagtatac gctagaaaca aggatttttt cataaaaaat gtttgaattt
    27121 tatcttttaa atgaatttaa ttttattttg attcgttcaa tcgagtcttc ttcttctttt
    27181 cttcgcatct cttcttcatg ataaacaacc atgtcttgat aaaattcgat catagcttcg
    27241 ccgaaatgtg tagatgaaat atcataaagt ttagcttcta aaacttttgg atctttagga
    27301 acttcactgg aaatataatc aataagtgct ggtgcaaagt cttcgtcggt ttcaaaagtt
    27361 ttccctaatg aaggatgatc gaacaatcgg ttcaaataag catttccttc cacgacacaa
    27421 ggtgttccgg ctgccatcgc ttctgtataa gtaagccctt gtgtttctga agtagaagca
    27481 ctgacaaaat aatctgccgc tttataataa agtgctacat cattgttgtc cacttctcct
    27541 gtgaactgca caaattcttc taactgcagt tctgagatca attcctctaa ctcttctaca
    27601 taaggtcctt ttcctacgat aactaatctg gcgttaggat aagcggagat gacctgagga
    27661 aacccattaa tcaaggcttg gatatttttc tcataagaaa tcctgcttaa agaaagaatc
    27721 atcaaatggt tttcctgaag acctagtgac tcccttaatt tgctgatatc ctgctgagtg
    27781 atatcagaac gtttgaattt ttcaatgtcg ataccagtag gaatcacgcg aagcggtgct
    27841 attacaccat agctgcgtaa tgtatcaata acacgttcac ttggacaaac tacacctgtc
    27901 gtatgatttg caaataatct agacaagtat tttacatggg attgcctgat cacttttcct
    27961 ttaccgatat aatgaaggta gtcttcatac atcgtatggt aagtatggat cagaggtatt
    28021 ttcaacttct tagctaccat cttcccaagt atccctgctc cgaattctgt atgggtatga
    28081 ataagatcta gttctagttc tttggcaacc aaataagcat accacatgcc tctaacaaca
    28141 actcttcgat ccttgaaaga aataaatggt acacttggca ttcgaatcac atctttttcc
    28201 aacttatccg cattaggatc ggtcgttgta aaaatataga cttcatgccc atgtctttct
    28261 aattcttgtt ttaatgtttt gatcgatgta gcaactccgc tgacttgcgg aaagtaggta
    28321 tcggtaaaaa agccgatttt catgtttttc gcctccaaac tagtccttga cctgatttac
    28381 tttttttaat ttgctagaga ctttttcatt cagtacactt tcgtatacat ttttaagttc
    28441 ttcaccgatt ttattgatac ttcgctcttt tgctgtttga taaccggctt gtgtcgtact
    28501 cggtagttct tgattggtaa tctgttggat cagtcggata aattcttcgt ttgtcttccc
    28561 catatagcag ttcttgctat cttctaacca gccattatac actggaatat ctcgaacaag
    28621 tacgttttgt ttgcttgcta aagcttctaa aacaacgatc ccttctgtct cttcataaga
    28681 agggaaaaag aatagatctg cacctgaata cgcaccttct atgatctctc cacgaatgta
    28741 accaggaaac aggacatttt caggatgatc ttcttttaca attttccgga tgttccgagg
    28801 aatcgagtac atgggaacat gaccaaacca aataaatgtg tattcgggca tcttcttagc
    28861 aatttctacg aaatcaatga ttcctttacg ttcgaaaaac aaaccgacac aaatgattac
    28921 tttttgatcc ggagacagtt tgaaatattc tctgaacttt tgttctttca ttggatcagg
    28981 gtgatatttc tctaagtcga tcccattgga aatagcttga atcggcacac ggataccata
    29041 gctttccaac aactgttttg aataaggtgt tggcgtgatc agatagtccg ctttttggta
    29101 caatcctacc agatattttt ttacgatagg agaaagctgg ttcgatccga taaaggaatt
    29161 tcggaaatct tcctctgtag aatgcgcatg atagacaact ttttttcctt ctcttctggc
    29221 tttattgacc atattatgac tattgattcc gtatgtattg atgtgcagga tgtcataatc
    29281 ttctttttca tctagtgtat aagagatacc gacttccgtc agagcacgtt tttgatgatc
    29341 aagcgcacgc ccgattccag attttgcaag catcttttca ctttcaaaat ataataatac
    29401 cttcacctta cgtccccctt cacttatata gtataacata gcctacaaac tgtcactcaa
    29461 acttaagccc tatttttgtc tattcttact gacaaaaacg ttttcttaaa aaagaacaaa
    29521 aaaactggcg tagctctttt acaagccaca ccagcttttg atacgttgtt tattttacat
    29581 attcatgaac aagttcaacg acttcttcca tcatatcgca ttctttcaat gcacgatcag
    29641 caagttcagc cattttcgct gtgtccaagc gtttcattaa actacgcgtt ttaagaatag
    29701 atgtcgcact cattgagaac tcatctagac ccatacctac tagcaatgga acagctgttt
    29761 gatctccagc catttctcca cacatacctg cccattttcc ttcagcgtgt gctgcatcaa
    29821 ttacattttt gatcaaacgt aaaattgatg ggttatatgg ttggtacaag taagaaacgc
    29881 gttcgttcat acggtctgct gccattgtgt attgaatcaa atcgttcgta cctacagaga
    29941 agaaatctac ttcttttgca aacttgtctg ctaagactgc tgctgctgga atctcgatca
    30001 tgatgccgac ttggatcgta tcagatactt ccttgccttc acttatcaat ttttgttttt
    30061 cttcttcaaa gatcgctttt gctgcgcgga attctttgag tgtagctacc atagggaaca
    30121 tgatacgtaa attaccatga acagatgcac gaagcaatgc acgcatttgt gtacggaaca
    30181 tttcgtcgcc ttgttcagat aaactgatac gcaatgcacg atatcctaag aatggattca
    30241 tttcatgagg taattgcaga tatggtagtt ctttatctcc accgatgtcc attgtacgaa
    30301 caactacagg ttttccttcc ataccttcta atacagcttt gtaagcttca tattggtcat
    30361 cttctgttgg gaagtctgga gaatccatat acaggaattc agtacggtac agaccaactg
    30421 cttctccacc attattatgg acaccaacta gatcttttgg tgttccgatg tttgcagcta
    30481 attcaaaatg cttgccgtca gctgtgacag tttctgcatt ttttaatttt tcccattctg
    30541 ctttttgtgc tgcgtaatct gcacctgctt tttcaaattc agctttttgt tcatctgtag
    30601 gatcgatgat tacatcgcct tcgatcccgt tgacagccaa aatatcgcct tctttgactt
    30661 tagcagtaat ttcttttgtc ccaacgattg ctggaatttc taaagaacgt gccatgatag
    30721 cagaatgtga agtacgtcca ccaatgtctg ttacaaacgc ttttacaaaa ttgcgatcta
    30781 attgtgctgt atcacttgga gtcaagtcat gtgcaacaac gaccacttct tcgttgatca
    30841 ttgatggatt tggtaaagta acgcctaata agtgcgctaa aatacgttta gcaacgtcac
    30901 gaatatctgc agcacgctct tgcatataag cattatcttc cattgcttcg aacataccga
    30961 tatacatatc cgttacttct tttagcgctg attcagcatt tacgctgttg tctttaatat
    31021 tttgcttgat ttgacctacc atttctggat ctgaaagaac catcaaatgg gcatcaaata
    31081 cttgcgcttc tgcttcacct aagctttgcg ctgctttttc acgaatttgc tgcaattctt
    31141 cagtagattt agctaatgca gcatccaaac gagcttcttc agccgcagta tcttctactg
    31201 ttgccttact gaatgttaaa tccggttgaa ctagcaggta agcttttgca acggctacac
    31261 cgtcactagc ggcaatccct tttagcattt caaccattat tcagataagc cttctttctt
    31321 cattgtttca acgattgctg ccattgcatc agcttcgtca gcaccttctg cagtaatagt
    31381 aacatcagaa ccttgaccta cacctaaaga cataacgccc atgattgatt tcaagtttac
    31441 tgatttacct ttatactcta agtttacatc agagttaaat ttgcttgctg tttgtactaa
    31501 tagtgtagct ggacgagcgt ggatcccagt ttctgctact acgtgaaatt ctttcttttc
    31561 catattaatc ggtctccttt aagtgagtgt tgtttttatg tgagggtttt cttttttagt
    31621 aattcagaga atcctaacaa atgccaccct ttcatctgta aagattaaca ttttttttcg
    31681 ttagatacaa cagttttcat tcaatttcag ataaaagtat tcaaattatt ccggattctt
    31741 tttcatcctt ttcttcacat tttataacaa acgtgtttat ttcctttttc ttgtcgcttt
    31801 ctcttctcct gacgtttatc attctttcct ttgaccctct ttgttttcat atgaaacgaa
    31861 ttacttgctt ccctttttat ttttagtata ataagagtca aaggtcagga atggtcaata
    31921 gagatttcac cttttctacc tcataaatct cttaaaaaac taggggttat tcttttacct
    31981 catgaaaaac gagatgtaaa atatggatgt acccattttt gtgaaaggac gtgaatgatt
    32041 catgctttgt caaaactgcg gcaagaatga ggcaacgatt cacttgtatg ccactgtcaa
    32101 tggtcagcgg acacaactcg attactgtca gagctgttat caaaaaatca aaaatcaaca
    32161 aaatggaggt ctgactaata tggcccaaaa tgatccattt ggatttggca gtttggacga
    32221 tcttttccgt tccatgtctc gccaaatgca acagcaagga aattatgagc aaacaccacc
    32281 aacacaattt ggcggaaaca acaacttcaa tggtggtcag ccacctcaag gcaatacaga
    32341 aggtttattg ggagaatacg gaatcaatat cacagaacaa gcacgacaag gtgatatcga
    32401 tcctgtgatc ggacgcgatg acgaaatcaa acgagtcatt gaaattttaa atcgccgaac
    32461 caagaacaat cctgtcttga ttggagaacc aggtgttggt aaaacagcag ttgttgaagg
    32521 tttagcacaa aaaatcgtag atggtgatgt accgcaaaaa ttaatggaca aagaagtcat
    32581 tcgtttagat gtcgtatctt tagtccaagg tactggtata cgaggacaat ttgaagaacg
    32641 tatgcaaaaa ttgattgaag agatccgtca agcagaaaat gtgatcctat tcatagatga
    32701 agttcacgaa atcgtcggtg ctggttctgc tggtgatgga aatatggatg ctggtaatat
    32761 tttaaaacca gctttagctc gaggagaatt gcaaatggtt ggtgctacta ccttaaatga
    32821 gtaccgcatc atcgaaaaag acgctgcttt agaacgtcgt atgcaacctg tacgggtaga
    32881 tgaaccaact gtcgaagaaa cgatcagtat tttgaaaggt ttgcaaaaac gttatgaaga
    32941 ctatcatcat gtaaaatata ctgatgaggc catcgaagca gccgcaactt tatccaatcg
    33001 ttacgtccaa gatcgcttct tgccggataa agccatcgat ttgctagatg aaacaggttc
    33061 taagaaaaac ttgacgatcc aaatcgttga tcctaaaaca atcgagaaaa aactgcaaga
    33121 agcagaagaa caaaaagttt tagcttctcg agaagaagat ttcgaaaaag cagcttatta
    33181 tcgcgatcag atcaataaac ttcaaaaaat gaaagaacgt cagctcactg aagaggaaac
    33241 acctgtgatt accgaaaaag atatggaaaa aatcgttgaa caacggacag gtattccagt
    33301 gggtgaatta aaagaaaaag aacagacaca actgaaaaac ttagcagatg acttgaaagc
    33361 tcatgtcatc ggacaagata acgctgtaga tcgagtagcg aaagcgattc gccgaaaccg
    33421 tgttggatta aacaaacaga atcgtccaat cggctccttc ttatttgttg gaccaactgg
    33481 tgtaggtaaa acagagcttg cgaaacaact tgcctacgaa ctattcggtt cacaagattc
    33541 aatgattcgt ttcgatatgt ctgaatatat ggaaaaacat agtgtctcta aattgattgg
    33601 ttctcctcca ggttatgtcg gatacgaaga agctggtcaa ttaacagaaa aagtacggag
    33661 aaatccttac agtcttgtct tgttagatga agtagaaaaa gctcatccag atgttttgca
    33721 tatgttcttg caaatcttag atgatggtcg attgacagat gcacaaggaa gaacggtcag
    33781 ctttaaagat acgatcatca ttatgacaag taatgccgga actggtaaag tagaagcaaa
    33841 cgttggtttt ggtgcggcac gcgaaggtgt tactcgttct gtattgaacc aattaaacaa
    33901 ctactttaca ccagaatttc tgaaccgttt tgacgggatc atcgaattca gtgcattatc
    33961 aaaagaaaac ttgatgacaa tcgtcacact aatgctagac gatgtcaacc aaatgctggc
    34021 agcacagcaa cttcacatcg aagttcctac gaatgtcaaa gaaaaattag ttgacttagg
    34081 ctatgatcca tctatgggtg ctcgtcctct tcgacgcacg atccaagaac aaatcgaaga
    34141 tggtatcgct gaattttatc ttgatcaccc ttctatccat gagttgaaag caaaactgga
    34201 taaagatgga aaaatcatcg ttacttctaa accagaacgt ttggctaaag aatcagccga
    34261 agaaacggct gaataaatcc agttttatag cgtgagacgg tatttctttg agaaatgccg
    34321 tctcattctt ttttcagaaa agtcaaaata ctgttcattt tataaaaaag aaattataat
    34381 aagagaaaca agcaattaaa aatacataaa agaggtgagc gccatgaaat tggtaaatgt
    34441 aacaaacagc cattcccgtc ttgtattaaa ccagcttgaa aacactgatg cccatctagt
    34501 caaggtctac acagccggaa ataccactat tgtctacact gaagcccctg aacataatga
    34561 aattctgctg atcaatgaca aacgtaaaat ccagccgaaa gaaatcgaag atgctaaaaa
    34621 ttatttctta gataaaatca aagacgccgt ttaccacgag gatgaaatca aagtaatcga
    34681 attggcaggc cttgttgaaa tctcgattcc aaaacatgaa ttaggcgcta cattagccgt
    34741 gtaaacaaat tttgaacata ataattaaag agcgtgggac aaaagtaaag aacacttttg
    34801 tctcacgctc taaacacgta taaacggcga aagcagaagc aactccttcg gaaataagct
    34861 gaaattcacg aaaattgctt ttcaaatttt tgtgaattcc agcttatttc ttggagttaa
    34921 acgcttctgt ctcagcctct ttttctttct agctttttga tttttctctt ttcttttgta
    34981 cttttctctt ttcattttca gttctacgcg tgtctttatt tttaactttt tcctctttat
    35041 ggatgattga tcgtactttt tgtgcaattt gctcgttttt gtcccagtct tttacatcta
    35101 ataatcgaca taatcgtaac atctcttctt ttttctgttt ttttctttca cgtctttgcc
    35161 attctgtttc catgtgtcac actctccttt ctttaatcat atgtacgcaa aataattttt
    35221 atattttttt gattagacat ttctatgatt ttaatatagt aaaaagagcc gtcacggaaa
    35281 atccgtcacg gctctaaaca aaatatgaga ggctgttttt gtttggctat tcttattact
    35341 tgatgcaggg cagcttgtgt caagacttct ttacatcaaa ctttttaatt ttacattggg
    35401 atatttatcc gcaaaccagc gttctgcaaa ttggttctcg aataagaaca acggttggtc
    35461 gaaacggtca cgagccaaga tattgcgact tgaactcatc ttctcatcca aatcttctgg
    35521 atcgatccag cgagcgattt tgtgtcccat tggagacatg attacttcgg cgttatactc
    35581 atttaacata cgatattgga atacttcgaa ttgtagctga ccaacagctc caatgatata
    35641 ttcttccgtt agatatgttt tataaagctg aatcgctcct tcttgaacta attgatagat
    35701 tcctttgtgg aaggattttt gtttcatgac attttttgca gtcactttca taaacagctc
    35761 tggagtaaat gaagggagtt cttcataagc aacttttagt tttccttcga acaatgtatc
    35821 cccaatctga taattgcctg tatcatatac accgatgata tcgcctgcta ctgctttttc
    35881 gacgttttct ctcgaatctg ccataaattg tgtgacattg cttaatttca gttttttatt
    35941 tgtacgttcc aaccagacat ccattcctcg ttcgaatgtt ccagaacaga ttcggacaaa
    36001 agcgattcgg tcacgatggg ctggattcat atttgcttgg atcttgaata cgaaacctga
    36061 aaattcttcc tcataaggac ttaccatctg atcatcttgt gttttgtgtc cataaggagc
    36121 tggtgccaat tcaacgaaag tctctaaaaa agtctgtaca ccgaagttag tcaatgcaga
    36181 accaaaaaat actggtgtct gatcgccacg agcaattttt tcttgattaa atgcatctcc
    36241 agcctctttg attagttcta cttcttctaa gacttgttca tataaggaat tttcagttag
    36301 aggatgattt tcgggaagca gtccatcttc atccaattct actaatcgtt catcctgata
    36361 attttccgga cgataaaact ctacacgatt atggtagata tcataaagac cttctagccc
    36421 tttacccata ccgattggcc aattcatcgg ataagattcg atatctaata gctcttctaa
    36481 ttcttctaac aattccaatg gttcacgacc atcacgatct agtttgttga taaaagtaaa
    36541 tatcgggatg ccacgttttt ttacaacttg gaataatttc tttgtctgtg cttcgatccc
    36601 ttttgcacta tcgattacca tgaccgcact atccacggcc atcaaagtac gataagtatc
    36661 ttcagaaaaa tcttcatgtc ctggtgtatc caagatattt actcgtttcc cttgataatc
    36721 aaactgcata acagaactag taacagaaat cccacgttgt ttctcgattt ccatccagtc
    36781 tgatttggca aaattacctg tttttttgcc ttttacggtc ccggcttgac ggatagcccc
    36841 accaaacaat agtaattgtt ctgtaatcgt tgttttccca gcatccggat gggaaatgat
    36901 cgcaaaagtt ctgcgattgt ccacttgttg ctttaatttt ggattattca taacctaact
    36961 ccatttcttc cattcaatta tttatatttt ctctaggcac agattgtccg atctcttaaa
    37021 gaaagacaat ttcatatagg gctgtgacaa aagccgtgta gcagtctctt tttccgagta
    37081 aacggcgttc tagagacagc ctatcagcaa taagcccacc caagccaaaa atacgaaaag
    37141 ctgtttttgc ttggctgctc ttattactta atgcaggata gctttttcac aacctttgtc
    37201 aactactaca actgaatcag tatagcatgg attcagcgaa tgaaaaagcc accaaaccat
    37261 aagagtcaaa tatttttttg tcagctgact aaaagaaaag acgtgttgct tgtttattca
    37321 agcaacacgt ctttcataac caagtttcca attatcttct tggctcgtca tcttcgaatt
    37381 cttttctgaa gtatcttcgt tcttcttcag gttccgcttc tgtttcttcc ggatcatgaa
    37441 aaatgacacg gattttaagg attcgagaac cttccatttc ttcagaaacc agcgtaatat
    37501 tatcgacatc aaacgataac ttttcgcctt catccggaat catgcctaat gctgtaatca
    37561 aataaccagc catcgtatct acatcactca tatgcagatc actgtcaaaa gcttcattga
    37621 actcatcaat cagcatacgt ccttggatga tatattcgtg ttcatcgatt ttttcataaa
    37681 gattctcaac ttcatctgat tcatcatcga tttctccgac gatttcttct aaaaggtctt
    37741 ctagtgttgc taacccaacg acgccgccat attcatctaa taaaatagcc atctgattct
    37801 gcgtcttttt catttcatat aacagatcat caataaagac cgtttcagga acgaataaag
    37861 gctcctgcat gattttcttg atatctaaat tatcaaagcc gaatttatgg gcagctttta
    37921 gtaaattctt tgtatgaagg attccgacta ctttatcttt gtcttcgtta taaacaggga
    37981 ttcttgaata gttttcggat aaaacttcat tcacattttc ttccacagtg tcgttgatat
    38041 caatcataaa tgcatccgtt cgtgggacca tgacttctcg ggcaactttc gtatcaagag
    38101 aaaaaacccc ttggagcatt tctaattctt cattattcaa tacgccttcg ttttcaagca
    38161 tataacgcat ttcatctctg gtcatttttg aatcttcatc atcaaaagtc atcggcgtga
    38221 tacgcgccaa taaacttgtg gaagcagaaa gcagccagac gaagggctta gctactacac
    38281 caatcaagcg tatcagccct gaagtgaact ttgcgacttc ttctgattta tttaaagcaa
    38341 tacgtttagg gtacaattct ccaaaaacaa tcgatacata ggtcaaaata gccagcacaa
    38401 tgatatttgc aatatttttt gccgctgtgc cgccacctaa taccggagct aaccgttccg
    38461 ataaagtatt agctagtgaa gcaccagaca aaatgttgac caaagtgatt cctacttgga
    38521 ttgtcgatag gaaattattt ggattctgca atatttttaa aagcttttga gatttcacat
    38581 ctccttcatc agctttttgc tcgattcgat tcttattgat cgaaacaaca gcaatttcgg
    38641 aagctgctaa aaaagcattg atcaatgtca aaacgatcaa taataaaatc tgcgctaaca
    38701 gcgactgact ctcagggtca gcattcataa tcgcattctc tccttataaa attaattttt
    38761 agtttacgat agaaaaaaac gtggcactat agccacgtta aaatggtatc acaaagcaat
    38821 tttctttgca ataaaaacaa gtgtactaaa actacctacg aggtcgtagc aattttcttc
    38881 ttgttttcat tttgcttgtc ttctttgacg attttgatta tataggaaat gatcgtcttg
    38941 cagattgcgt aaaaaggaac acctaagaag ataccaagca atccggcaat atttccagct
    39001 actagaagaa cgataatgat cgttaatgga tggattttca gtgatttccc aattacatta
    39061 ggataaatga tattcccatc caactgttgg acgattagca caaccacaca acaaagtaat
    39121 gcttttaccg gatcattgaa gactgttact agaaatgcag gtgctagtcc tagataaggt
    39181 cctaaatatg gaattaggtt tgtcaatccc gcaatgaccc caaataagaa agcataatcc
    39241 acaccaatta ccatatatcc taaaaatgtg aaggtaccaa cgaataaaca ttcgattgct
    39301 tgtccgctaa tgtaattagc caatgtttta ttcagttgcc ccaataactc cacaatttgg
    39361 tttcttcttt tttctgggaa aaactgttgg atgtttggca ctagtttttc tccgtctttc
    39421 aacatataga acaagatgaa tggtgctgta atgattacta cggttgccga agcgatcgtt
    39481 ccaacgatcg aacctaaact attggatact ccactaagga attgctgaat gattgtcccg
    39541 taagaaatgt ctaattgctc aaaatattta ttgatatcta cttccttgaa caaaggcaat
    39601 tcggctacct cttttaacca gctttctacc tgtttgatga aatcaggcat attagatgcc
    39661 aatgaggaaa tttgctgtac tagacttggg atgacactaa gtaaaatcca aataattgct
    39721 gcaactaaaa ggagcagcac aattgcgaca gcccatattc ttttgatttt tgctttcatc
    39781 aacagcttga caataggatt caataaatag taaagaaagc ctgcaatcag tacaggtgca
    39841 aataacgtgg aaaaaaatgt cccgatcggt tcgaaaataa agtttatttc tgatgaaatc
    39901 atgatcaatg cagctatgat caataattca agcgaccaaa acattagttt agactgtcta
    39961 agtttttcaa acaatagatt tcctcctttc tttcttacta gtatatatta tattcgttaa
    40021 aaattctttt attctttttt tatttttgaa aacttgccat actttttatt tgttttattt
    40081 tccagtatac tatacgaaag gaaggtggct agaccatgaa agttgtacaa acaaaagata
    40141 caatgagcaa tatttactta gatgctgtac ggatcaggca tcaagttttt gtagtcgaac
    40201 agggtgtgcc tttgtctcga gaaatagaca aagatgaagc ccattgtatc cacttcgtcc
    40261 tgtactcaga taaaaaagaa ccgcaaggaa ctgtacgtct tttgccttta gaaaacggaa
    40321 aaatgaaatt acagcggatg gcgattcttt ctgaatacag acaccaaggg ttaggaaaaa
    40381 tattgattga agaagcagaa aactttgcta agaatcaagg ctataatacg attttattag
    40441 gggcacagtc cacagctgaa actttttacg aaaaactagg atatacagct tacggcgatc
    40501 cttttgaaga tgctggcatg cctcatattt atatgaaaaa gactttataa aaatttattt
    40561 cgaaaaaagc aaaaaacagc aagcttttga gaaaaatctc tcactggctt actgttcttt
    40621 tttgtgttta cttacgcgac aattgcttgt aacggttata ccaaatatca atatagcctt
    40681 ccgagaacgg gccatctcca ttattgatcc agtcaaccag aatcttcaca ttttctttta
    40741 ggatgaagtc aatatcgttc gggtaattca tcattttgct gtgcatctca tattcatcga
    40801 catccaatag tcgtttctcg ccgtcaggaa ataccttgat atccaagtca tagtcgatat
    40861 atttcaaggc ctcatcgtcc agcaaaaaag gtgaagctag attacaataa taggaaaccc
    40921 ccttttctct gatcattgct attacattga accagtattt tttatgaaaa taaacaatcg
    40981 ctggttcgcg cgttacccat cggcgtccat cagattcagt gactaatgtg tgatcattca
    41041 cgccgatcat agagtgttcg cttgttttta ataccatggt atctcgccac gttcgatgca
    41101 atttgccgtc gtgcttgtaa ctttggatcg tcacaaactc tccttctttt ggaactccca
    41161 tagcaaccct tccttaagca gcattttgtg ctttgtgttt gggtgttcat tacaccgaca
    41221 tcataattat tatatcaata aaaatgagct ttgcctagaa aggattccta ttgtttcgat
    41281 ttttctctaa ctgatctacc agtttcattt ggaccttagg aaaaacgacc gaatcaaatg
    41341 catcaggctt caaccacttc gaagttttgt tctcggtaaa ttcttgttct gctccctcgg
    41401 ttgcccgtcc gtaaaaaagg agaacatgcc atttcagatg actaaaaata tgagtaactt
    41461 ctcctaaatg tcgtgtctgc caaacaaaga gttcctgctt ttcaaatggg agattttgct
    41521 cttcttctgc tactaggtca tcaaacagat cgatttctgg ctttgtttcc cattcttttt
    41581 tcaatcgctc atactcctct tgtgtcactt ccatcattgg aaatgtccac atattcgcca
    41641 gcaatttttg gctatctctt tcttcaaaat aatacgctcc agaatgattt tgaagagctg
    41701 cactgatata ataaacgtct tttggctttg ctttttttgt ttttacagga aaactcgttt
    41761 ggattcctcg tttgttagct aaacaaaagg cttggatcgg acaagtctca cactttggag
    41821 aagttggtgt acagatagct gaacctagat ccatcattgc ttggttgaat tcacctggat
    41881 gcttttcatc aatgattttc cgcatcgctt catcaaagat tttcctgcta gaagcttttg
    41941 cgatgtctgc ttcaatgcaa aacaatctgc tgactactcg catcacgttg ccgtcaactg
    42001 caggttctgg aagtccaaat gcgatacttg caatcgcgcc tgtcgtatat ggtcctattc
    42061 ccttcaatga gctaatttct tcaggcgttt gcggcatttc cccatcaaat tctgacatga
    42121 tctgtttagc agcagcttgg atgttccggg ctcttgagta ataaccaagg ccctcccatg
//
LOCUS       DACGMI010000020        41724 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.020, whole genome shotgun sequence.
ACCESSION   DACGMI010000020 DACGMI010000000
VERSION     DACGMI010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41724
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.020"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(33..743)
                     /locus_tag="IXT46_001213"
     CDS             complement(33..743)
                     /locus_tag="IXT46_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAQ4947138.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(740..2212)
                     /locus_tag="IXT46_001214"
     CDS             complement(740..2212)
                     /locus_tag="IXT46_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4947139.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            2350..2823
                     /locus_tag="IXT46_001215"
     CDS             2350..2823
                     /locus_tag="IXT46_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4947140.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(2976..3527)
                     /locus_tag="IXT46_001216"
     CDS             complement(2976..3527)
                     /locus_tag="IXT46_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4947141.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            3632..4162
                     /locus_tag="IXT46_001217"
     CDS             3632..4162
                     /locus_tag="IXT46_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAQ4947142.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(4645..5088)
                     /locus_tag="IXT46_001218"
     CDS             complement(4645..5088)
                     /locus_tag="IXT46_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4947143.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(5104..6264)
                     /locus_tag="IXT46_001219"
     CDS             complement(5104..6264)
                     /locus_tag="IXT46_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4947144.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKKQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            6771..8471
                     /locus_tag="IXT46_001220"
     CDS             6771..8471
                     /locus_tag="IXT46_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947145.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQKKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(8573..9406)
                     /locus_tag="IXT46_001221"
     CDS             complement(8573..9406)
                     /locus_tag="IXT46_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAQ4947146.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCQVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQSQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(9710..11875)
                     /locus_tag="IXT46_001222"
     CDS             complement(9710..11875)
                     /locus_tag="IXT46_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4947147.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            12135..14429
                     /locus_tag="IXT46_001223"
     CDS             12135..14429
                     /locus_tag="IXT46_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAQ4947148.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGFPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            14422..15087
                     /gene="pgmB"
                     /locus_tag="IXT46_001224"
     CDS             14422..15087
                     /gene="pgmB"
                     /locus_tag="IXT46_001224"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAQ4947149.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKCH
                     DHG"
     gene            15080..16087
                     /locus_tag="IXT46_001225"
     CDS             15080..16087
                     /locus_tag="IXT46_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAQ4947150.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            16109..17128
                     /locus_tag="IXT46_001226"
     CDS             16109..17128
                     /locus_tag="IXT46_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4947151.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDPVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(17409..18776)
                     /gene="nhaC"
                     /locus_tag="IXT46_001227"
     CDS             complement(17409..18776)
                     /gene="nhaC"
                     /locus_tag="IXT46_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAQ4947152.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(18886..20307)
                     /locus_tag="IXT46_001228"
     CDS             complement(18886..20307)
                     /locus_tag="IXT46_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4947153.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(20550..22427)
                     /gene="tdc"
                     /locus_tag="IXT46_001229"
     CDS             complement(20550..22427)
                     /gene="tdc"
                     /locus_tag="IXT46_001229"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAQ4947154.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(22718..23974)
                     /locus_tag="IXT46_001230"
     CDS             complement(22718..23974)
                     /locus_tag="IXT46_001230"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAQ4947155.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEVEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            24554..25855
                     /locus_tag="IXT46_001231"
     CDS             24554..25855
                     /locus_tag="IXT46_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAQ4947156.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(25924..26523)
                     /locus_tag="IXT46_001232"
     CDS             complement(25924..26523)
                     /locus_tag="IXT46_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4947157.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            26777..27658
                     /locus_tag="IXT46_001233"
     CDS             26777..27658
                     /locus_tag="IXT46_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947158.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTVVEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            27671..29281
                     /locus_tag="IXT46_001234"
     CDS             27671..29281
                     /locus_tag="IXT46_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAQ4947159.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRMGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(29358..30017)
                     /locus_tag="IXT46_001235"
     CDS             complement(29358..30017)
                     /locus_tag="IXT46_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAQ4947160.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(30300..30965)
                     /locus_tag="IXT46_001236"
     CDS             complement(30300..30965)
                     /locus_tag="IXT46_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947161.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(31112..31717)
                     /gene="dhaL"
                     /locus_tag="IXT46_001237"
     CDS             complement(31112..31717)
                     /gene="dhaL"
                     /locus_tag="IXT46_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAQ4947162.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(31745..32728)
                     /gene="dhaK"
                     /locus_tag="IXT46_001238"
     CDS             complement(31745..32728)
                     /gene="dhaK"
                     /locus_tag="IXT46_001238"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAQ4947163.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            complement(32730..33125)
                     /gene="dhaM"
                     /locus_tag="IXT46_001239"
     CDS             complement(32730..33125)
                     /gene="dhaM"
                     /locus_tag="IXT46_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAQ4947164.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            33279..33599
                     /locus_tag="IXT46_001240"
     CDS             33279..33599
                     /locus_tag="IXT46_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAQ4947165.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(33711..34580)
                     /locus_tag="IXT46_001241"
     CDS             complement(33711..34580)
                     /locus_tag="IXT46_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4947166.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(34676..35950)
                     /locus_tag="IXT46_001242"
     CDS             complement(34676..35950)
                     /locus_tag="IXT46_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003745485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4947167.1"
                     /translation="MLRYLFVYYVFFLVSYPILGGFVWFIGVWCYVFLYKHKQKEWVD
                     VPLSVEPFITIMVPAHNEEIVIEDTIEYLMTKLNYHNYEVLVTDDGSTDQTPEILARL
                     MKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDALIRYVNYFIRP
                     GARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLYAYSGANTMYR
                     KEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTLKMLYRQRKRW
                     AKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVLFAGLIGHYVY
                     QGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFAPLYMLLFWIV
                     NAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(35976..36485)
                     /locus_tag="IXT46_001243"
     CDS             complement(35976..36485)
                     /locus_tag="IXT46_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947168.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(36660..38795)
                     /locus_tag="IXT46_001244"
     CDS             complement(36660..38795)
                     /locus_tag="IXT46_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4947169.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(38878..40533)
                     /locus_tag="IXT46_001245"
     CDS             complement(38878..40533)
                     /locus_tag="IXT46_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4947170.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(40535..40849)
                     /locus_tag="IXT46_001246"
     CDS             complement(40535..40849)
                     /locus_tag="IXT46_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAQ4947171.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            41019..41279
                     /locus_tag="IXT46_001247"
     CDS             41019..41279
                     /locus_tag="IXT46_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAQ4947172.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            41293..41607
                     /locus_tag="IXT46_001248"
     CDS             41293..41607
                     /locus_tag="IXT46_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAQ4947173.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
BASE COUNT        12222 a         8608 c         7514 g        13380 t
ORIGIN      
        1 ttttcacaac ctcctacatg gtgttcaaaa tattattcgc cttttgcttc tttcactaat
       61 tttgcgaatg cttgttgttg gaattcagca gctaaggctt tcgtacgttg ttcttgctct
      121 gctttgctca tttttggatt ttcagtcatt gcttttacca taccgtcttg aacataagct
      181 tttgcttcac tttccatcgt actttgctgt ttcttcacta attcagctaa cttggctgct
      241 tggtccgtac ttaattctac ccatgtctct gggattttga atgtattcac tcggctgtca
      301 tattcgtgat tgttatcagc aatattgaac cagaatttat acatgtcgtt tttgtattcc
      361 caataagtag ttttcgtcac tttttcagca tcgccgtctg tcttttctac tttatttgtt
      421 tcgttatccg taccagttgc ttttggtttt tcttgttttt catttgttcg gtaaagatac
      481 actttttctt ttccattccc taaagcttta tacaaaagca tatctgctcc ttgggaatca
      541 gcactggaaa caattttttc tgtttttgtt tccgttactt tttccattcc aaagtgattg
      601 gacaaattag cgacgatcaa acttagtgaa gcgacgaaga ttagtccgaa aatcaaagat
      661 aaaaaggttt gccatgtttt tttagcgaac acgttcgtta aagcaaaagc aagcaagctg
      721 acaatcaaaa ctccaataat catgcattat cccccgcttt cattagaaca ggttcttttt
      781 tcttcaataa aaaggcaata ataaagccaa gaatcccaaa gatgatcgct acgataaacg
      841 cggcatggta acctgacagt gtggcattga ttgcctgatc tttataagct aatggcgtat
      901 tatccaatac agatttgctt gggatatttg cttttgtcac attcgtcaac acactgatca
      961 aaatagctgt accaatcgag cttgcgattt gacggaatgt attatttacc gctgtcccat
     1021 gactgatcaa gttatttggc aatgcattca taccagaagt cgttaccggc atcatgacca
     1081 tggagatccc aaacatacgg atcgcataaa ggatcacgat atataaaact ggagtcgttt
     1141 ttgtcaagaa agcaaatggt gcagttgccg ctgtcaaaat gaacatccct gtgatggcta
     1201 aacgtttcgc gccgtattta tcgaaaatcg cacccgtcac aggcatcata gcccccatga
     1261 tcaatgcacc cggcaacaac atcaagccag aatggaatgc tgattctcca cgaatatttt
     1321 gaatatacaa tggtacgacc atttctgccc ctaccatcgc catatttgtt acaccagcta
     1381 aaacagctgc aatcgtgaat gtagatgatt tgaatacacg aagttccaag aatggatgtt
     1441 ccaaatgtaa ttgacgccat gagaacaagg cgatgaaaat cacaccaaca actaagaaac
     1501 caattacttt caagcttccc cagccgtcat ctcctacact agaaaatccg taaagtaaac
     1561 taccgaatcc aatcgttgat aaaatagcgg ataaaatatc aatgctagga tttgacaatg
     1621 gaataacact tttcattagg aagaatgcta aaaccaagac aagaacaacg attggcagta
     1681 ccataccaaa caagtcacgc caatggtagt tatcaatgat ataaccagat aatgtagggc
     1741 ctaaagcagg agcaagtcca ataacgatcc ctgacatccc cattgctgat cctctttttt
     1801 ctggcgggaa aatagatagc atgatatttt gcaataatgg catcgatact cccacgccgc
     1861 aagcttggat caagcgaccg attagtaatg tactaaaatt aggtgctgta aagcaagtaa
     1921 tcgttccgat caaaaagatc gtcatggcag aaagatataa atttcttgaa ctgaatttat
     1981 tgatcagcca tgctgttatt gggatcatga tcccgttgac tagcaagaaa ccagtcgtta
     2041 accattgcac atcagacgct gaaatatcga aagctttcat caatgtagga aaagctgtcg
     2101 tcaataaggt ctgattcaaa acggtacaaa atgtaccaat taataagaca acaactaaaa
     2161 gtgtccgatt atatggtttt ccgtaaatat ctacgggttg gttgttactc atatttctcc
     2221 ttctttctga attttttctg aaactactag aatactttag tcctaaattc gctatttgtc
     2281 aacctacttg acacataagt taatacggat ataattaagg gaagcaagag gacaaaagga
     2341 gtgacaaaaa tggttggggc ttcccttaaa cgtttgttgg aaaatgatca attggttgtt
     2401 ggcatcagtg aattaagtga tatcgtaggt gtgtctccac gtcaattaag gtattgggaa
     2461 caaaagggat tcattcgttc gatcgaagct gatgcgaatt gtcctagaaa atatcgttta
     2521 cctacagtca taaaagtaga actgatcaaa aaatatttag atgacggatt tactttgtca
     2581 aaagctgcag aaaaggcaga aatccgccaa aagaaaatgc accatgtccg taaagttttt
     2641 tcaaaagcaa tcaaagatat cgaattgatc gacgaacgct atacgatttt acaaatcggt
     2701 aacttcaaag aagagaatgc taagatgtac atcattcatg acaacgagac agacgaatta
     2761 acttacaagc tccttcctgt cgatgaaaaa gctgactacg aacagttgtt aaaagaactc
     2821 taaacgccac taatctccta agtaccaagc tttttaataa gtagatgcta cataaatact
     2881 tgaaaaaagg cctgtttgaa cataagaata tccgaacggt gatctgcgtt tctttcatat
     2941 agaaaggaat tctccatcac tgttcggata tttttttatt tttttcggtt actttcttct
     3001 aatacatctg ttagccaatt tgcatattct gtttcccgat tgatcgcatg cgctaaaatc
     3061 aggtagtgtc cgtaattttc atgtttttct ttttcagtag gaaagatcgt tttttttcgc
     3121 tctaatagat gaagtcgttt ttcttcatga aggtcacgct gctgctgaat aatttctact
     3181 aatgccggat cattcacgtc tttgacgaaa tacaatttca gaacaaattc gtctcgatta
     3241 accggtagtt cattggttgg tgtatgaatc cactctgcca attgttcctt cccttcttct
     3301 gttaattcat aaactttctt ttccaatttt tcacctgtga tctctacttg atgctgaatg
     3361 attccttgct cttccatttt tgcaagttca ggataaatct gactatgttt tgcttgccaa
     3421 aattctccta tttcattttt gaacgattga ttcaattcat atcctgtcat cttcttctta
     3481 cttaataacc ctaacaaaat atatcgaagt gtattttttc ttgccatcag ttttccctcc
     3541 ttgacaaatc tttaaatcca ttctatcata aatgagtaat cgaaaacatg tagtttatta
     3601 catgttttaa tttataagga gatgcttaaa catgaaagaa tttaaagaat tggaagattt
     3661 tattggaact cactttatct atacgtatga caatggttgg gaatatgaat ggtatgccaa
     3721 aaatgaccat actgttgatt accgtatcca tggcggaatg gtcaaaggcc gttgggtaaa
     3781 agaccaagaa gctgatatcg ttaaattgac ggacggcgta ttcaaaatca cttggacaga
     3841 gccaacaggg acagacgtgg cattggactt tatgccaaat gaaaagaaac ttcacggaat
     3901 gatctttttc cctaaatggg ttgaagaaca tccagaaatc actgttactt tccaaaacga
     3961 acatatcgca gaaatggaag cagctcgtga aaaatatgaa acttatccaa aattacttgt
     4021 tcctgaattt gctacgatca cttatatggg tgatgcaggt atagacaatg aagatgttat
     4081 tagcgaagaa ccatacgatg gaatgccaga tgatatccgt agcggaaaat acttcgatga
     4141 aaattataaa cgagtaaaat aaggttgtga aagagaggtt gtgaaatcag cgttctgacc
     4201 tgagtattag agaaagaaac ggaaaaatag ttcctcatgt tttgccgttt tttgagctaa
     4261 taccgagggt cagctgattg aacaccgttt atcaagaggt tgtgaaatca gcgttatgct
     4321 ttgagtaata agaacgctag ttagaaaata gcttttcata ttttctaggc tagtgggctt
     4381 attaccgaga agcagccgtt tgaacaccgt ttatcaagag gttgtgaaat cagcgttttg
     4441 acctgagtat tagagaaaca aatggaaaaa tagttcctca tattttgccg ttttttgagc
     4501 taataccgag ggtcagctga ttgaacaccg tttatcaaag attgtaacaa ctgcatattc
     4561 acacagttaa attagtgact tcaaaatgaa ataatgctcc cagcaaaaaa ttaggctggg
     4621 agcattattt cgttattctg ttcatcaaaa atcagcgttt tgattccatt tcatcacaag
     4681 ttcctcctca tttactgctt catctttttg ctgtgtttga attgtaaaac cttgtgaaag
     4741 atagaaatga atagctgatt gatttttttg atagactgtc aaagtcagtg ttttattggt
     4801 ttcttttatt tttttcatta gttgcgtacc gattctttgt tgccggtatt cccttttcac
     4861 aaagattcct gcgataaact gatcaatcac cccagcaaaa ccaataattt cttgatctat
     4921 ttctgctaag taaatcactg catctggtaa agctttccta acagattcta cttgattctc
     4981 ccaataagtt gatggaatga attcatgaga atccaagtta gcatgcagcc aaatcgatag
     5041 aacagattcc agttctttgg cagacaattt tgttgttgtg cggatcattt tttctctcct
     5101 tacttattca ttgattttaa aataaaaacc atttttttga agctctttta caagttttcg
     5161 cccctcaaaa aagtatatct tctcttgttt tacttttcta ataccaaaag aaacagcaac
     5221 tttaggatca tcagctgaaa cgattcgata agttccacca ggcaattgat ccagcttgac
     5281 tttcccatga tggtcgcttt gtactgaaaa cggcacacca tttctagtaa gtgttttttt
     5341 cttatgtttc aaaatgaatg aactaccatt taccggtttc cctgacgaat cactaataat
     5401 aaatgaaaaa tcaagcactt ttttacttaa tctatactga tagattagtc gtccgataaa
     5461 cactaacagt atgactacag ctattatcgt tcctgcaaga ataaaccatt gccgcatggt
     5521 tctttcctga tttccttttc cttcttcttt ttttaccgat tcgttataag gaatccgatg
     5581 tcctgtcact agcaaacgat gcgtgttgat catatacggc gtacatgtaa gcaaggtaac
     5641 taagtcttct ccttctgaaa tcgttagaac agacgtgtca tctggcagta ccacttgtat
     5701 atttttaact tgataagcca atttctcccc caaaacagtc aaaataaacg tgtctccgtt
     5761 ttctaaacga tctaattcgg taaataaccg tcgattaggt aaaccgctgt gagcagagat
     5821 cactgaatgc gtcgaatttc caccaagcgg gaaagaggtt ccttgcaaga cgcctgctcc
     5881 attttcaagg atcctaccat tgagccgatc ataaagtgaa atatttaatt ggatcttagg
     5941 tatattgata cttccgatca gccattcctc taattggctg gatgttgtac tttcatttct
     6001 gttcttttca ttgaaaggat cagtaccagg attgaatcct tggtcagtta atcgttgttt
     6061 tttctcctcc attttctttc gctgcacttc aatttcagct gcggtccgtt tttgtacttg
     6121 ttcgatacgt ttttgatcaa taaaactatt taaagaatcc acataaaatg gatataaagc
     6181 gatcagtaac cctacgacga tacatattaa taaaaacaaa cgaaacaaaa gtcgacgaga
     6241 ctgtttttgc ttactctgct tcacatgtgt cctcccttgc aagttttttt gttctttctt
     6301 ttattatatg ggttcaggaa aaaaatagaa aatgaaagcc gatgaggttg tgaaaaagct
     6361 gtcctgcatc aagtaataag tacagcccaa aaaaatagct actcatattt tttgttgggt
     6421 tgggcttatt accgcagatg caagcttttg aacaccgttt aaggaagagg ttgtgaaaac
     6481 tgcgttatgc tttgagtaat aagagcgcta gtcagaaaac agcttctcat attttctagg
     6541 ctagtgagct tattaccgag aagcagctga ttgaacaccg tttaccgaga ggtcatgaaa
     6601 aagctacttt gtttcgagta ttaagaaaaa ttctgtttca aaacaaggag atgcaacaaa
     6661 acttatgtcg catcctctct ccttagaact ttcacttatg tttttcttgt aaaattcata
     6721 aatattttca tgaattttct aatttcttgc ctacctctcg cataggatat atgatgaatt
     6781 tatctaaagt ttgcaaagga gttcgacaat tgaaaaaata tggcccattt ttagcaattt
     6841 ttttcattgc tttggcattt ctcatgcctc atttattcac acataaacta attttgggtg
     6901 ctgatgcccc attccattac aatcggttct atgatgccgc gcaacaaatt aaatatgggg
     6961 atttccatta ttttccttcc ctttatggat tccagcaaag tggcaggatc gtgaatgccg
     7021 tttacggccc atttttcgct tatttacaag gattgatcgt gttgcttgca ggtagctggt
     7081 ttcattatca gattctttca aatttcattc tttatcttat ttcaggattt tctatgctga
     7141 ttttactgag atatgtcaat gttcgaaatt gggtaagtgt accagtagcc gttttattca
     7201 tgagtacgta ttctattcaa tactggtcta tcaaccaagg attcactagc tgggggactt
     7261 gtttttatcc tttatgtatg atccctattg ctgatttcgt ccttcataaa aagttccctg
     7321 ttatcaaagt cgctgtctca gtgggactta tgacacagat ccatttactg tcttcgatca
     7381 tgttagcttt gatgtatatc cctttttatc tttattactt ttttaaccag actgaaaaag
     7441 gaaaagcact gcttcaactg attaagtcgg tcttgcttta ttttgttctg acagcaaata
     7501 tttgggcagg attagctatt gtttacagtg ggaataagat tcttcctccc tttgttaaca
     7561 gagaaatgag tcaaaaggcg atagatctgg atggcagtta ttggctccat taccctaagg
     7621 cctttcctat attgatatta tcaggttttt tgctttttat tttctttcaa caaaagaaca
     7681 ccttattcca aaaaatcgtg ttgtacacaa gtcttgtttt cttttttctt tctactagct
     7741 tgattccatg gacgacattg atcgaaaaaa atgtgccttt tattagtttg atccagtttc
     7801 catttcgatt tttcgtgcca tttacgctat tgcttctact ttaccttgcc ctttcactga
     7861 accagtggtc tgaacaaaag tggttccgtc ttttaagtat atttggcatt cttatttttt
     7921 cagcacagac gatccagaac ttataccagc atctggaaaa gtgggaaaat gaaacatttg
     7981 tcagtcgaca tacttatcta ttcgatacgc cggaagaagc aaggaaaaca ttcttcagca
     8041 aagatatgtc taccagcttg ttcgttttcc aaaaaaccac acctgactat ctgccaatct
     8101 ataaggagac aaaagacaat aaatacgacc ggtataacga agaaatacta gaaaacgaaa
     8161 caacttttat aaaaacacat ccaggcggtc ttttgacaat caagtggaaa aacactgggg
     8221 acaaaactgt tcatatccct gttatcgtct acgatcggac tgtgctacag caaaatggaa
     8281 aaacattgac tgattatgaa gtaacagata tcgggacccc aatcgtgaag cagaaaaaag
     8341 gaatcaacga gctcacgctt cattatcaaa cgccaatcta tttctatttc attctttctc
     8401 ttactttgat tggctggttt accttgctat gtttatttat ttatcataga tacaagcttt
     8461 tacgtgctta ggcaaaaggg ataaatacat ccgatcaaaa aactctccaa acggtataat
     8521 cgtttggaga gttttatttt aatcagtttt tttatgttat atgttatatt ttttattcgt
     8581 tcacatctaa ttcgatttcc accccgtagt gatcactgat gattggacta tcgatcccat
     8641 caaaaatccg ttgatatttt ttaacctgca ttccttcagg gacgaaaata aaatctatac
     8701 gcaatttttc tgtattttgt tcccaaccat ctattttctt ttccacagta gctgcttttc
     8761 ctttttcatt cgcgacaaca tacgaatctt gaagaagaag gcaactttct cttacagtat
     8821 aataaccttg agagtctact ggattattga aatcacctag gaaaaaaagt ggtacgcgag
     8881 tttccaaaaa gtagttttcc aagtttttcc actcaaaata aaagccactt tttttatctg
     8941 tccaccaaga aaagtggcag ctcgagacaa aaatgtcctg atcatctatc tttgttttcc
     9001 caatcaagat cttgcgtgtc tgataatctt ctttcttttg agattgggag acggtaagga
     9061 cctgactttc caatgttttt ttcgtaagca gtgcatttcc ttcttcatat ttatcataac
     9121 cgatgtggct catttcccaa ctccaaaaat actcttttcc gtgttccttt aaaagctgaa
     9181 ctaaacggta ggcaaaatta tctttacgga taggtacttg attctttacc tgacagaact
     9241 tcattagctt cgcaggttct acttcttcag attccagtaa ttggttgatt tcttgtaaag
     9301 caatcacttc ataatcttct aacaggatct tatctgctaa ttcttgcaat tttttctctg
     9361 gttctggctc aagccagcta tgcgtgttga gtgtcatgaa tttcattggt tttctccttg
     9421 tcttcatttc gaaacaaaag ggttgtgaca aaatttttgt cacaacctct ccagcaaata
     9481 gtgttctcct gctaactcct cagtaataag ctcaatggac caggagctat tttttgtttg
     9541 gctgttttta tcacttggtg cagggcagct ttttcacgac ctctccacta aacagtattc
     9601 aaactgctgc ttctcggtaa taagcccaac caaacgaaaa ataggaggag ctatttttgt
     9661 ttggctgttc ttatgacttg atgcaggaca gctttttcac aacctctcct tacattttaa
     9721 tggagccgat cactttacca gctgtcactg tacctaattg cttgatcact acttcttcta
     9781 ctttatcgtt tgtaaatacg atcatgatcg ttggatcttt ttcttcgttt tggatcacat
     9841 caagatccat ctcagctaat ttcgttcctg ttcctacttc ttggccttct ttgacagcaa
     9901 tctcaaaagc tggctgattc atttggactg tatcgattcc catatggatc aaaacttcga
     9961 taccatcttt cgtttccagc ccaattgcat gtttgctagg gaaaatactt gtcacttttc
    10021 cagcgatcgg cgcaacaact tctcttgatg ttggaataac agcaaagccg tcacccatca
    10081 ttttttgtga gaataccgga tcttttactt cagataaagg aatcacttct ccagaagctg
    10141 cggaaactag ttcttgttct atacctaagt attgcttact acctgcttgt ccatttcctg
    10201 tagaaaccat ttctggctct ggaatctctg ctcctgattg cagcagatct tcgatatctg
    10261 atttcaagac atctgctttt ggtccataaa ctgcttggac tccattgtct ttgacgatca
    10321 atcccatcgc ccctgctcgt ttccaggctt cttcagtccc tactttttct cgatcattta
    10381 cacttacgcg taaccgagtc atacaagcat cgacatcttt gatattttct tttcctccca
    10441 gcaaatgaat gatctggacc acttgctgat ctgctgttcc tgttccgctg ttagatacaa
    10501 cggtttcttc actgtcattg tcgtaatttc cgttacgtcc cggtgtagca aagttgaatt
    10561 ttttgatcaa gaaatttgct aagaaatacg taacaacacc aaaagcgatc acacacaaca
    10621 cgaagttgat aagatctcca cctagacccg ctttgatagc taacggtgtc cgagtcagca
    10681 attcgatatt cccaaatgaa tggacccgca atggcaagat atctgccatc gcaaatgcag
    10741 ccccttggat cactgaataa atgacatata atggcacagc agcaaacata aacatgaact
    10801 ccaatggttc tgttacacct gttagaaaga cagccaacgc tgctgaaaaa tacattgatt
    10861 tatatcttgc tttcttatca ggatcgacat tacgatacat cgcaaaagcc attcccatca
    10921 agatacctga agaaccaatc atttgtccta ctttgaaacg agccggcgtc cagttatgca
    10981 acacaaactc atattgcgac atatcccctg cacctttaag attcactaaa tcagtggccc
    11041 aagccaacca taacggatct tgcccaaata cttgtgtccc cgcctgtgcg cctgataaaa
    11101 tctcatacga tccgccaagc tgtgtatagt tgataggaat cgtcagcata tgatgcaatc
    11161 caaatggcaa tagtaaacgt tctaatgttc caaataaaaa cggtgctaga atcggtgcgc
    11221 tttcttgtga ttctgcaatc cataaaccaa aattattgat tccagcctgt acgtttggcc
    11281 acaccacagc aagaatcaat gccacgattg ttgaccataa gataacaaca aacggaacaa
    11341 agcgctttcc attgaaaaat gacaaagcat ccggcaattt tctataatta tagtacttat
    11401 tataagccat tgccccgaca aatccagcga tgatccctac gaatactccc atattcaaag
    11461 ctggtgcttc caatacactt gtaaaaaatc ctttaaccat gatcttcgta ccgaacagag
    11521 tgtgggtaaa tgcatcttca ttcgcaagca tgtcacttgt gacaccaaag atagccccag
    11581 tgatccgatt gattaaaata aatgagatcc cagctgcaaa tgctccgcct gctctttctt
    11641 ttgcccaact tcctcctatt gctaaagcaa ataaaatatg aagattacca ataattgccc
    11701 aaccaatatt ttcaattact ccgcccgttg tgacaagcgg cgtccaatca ggattgatca
    11761 agggaattga tttccctata ctgatcatca acccagctgc cggcataact gctaccacaa
    11821 ccattaaagc ctttccaaat ttttgccaaa actcaaaact aaatatcttt ttcattccgt
    11881 ttagctcctt tacgcaatcg gtttcgttaa acgtattata gcgtgcgttt tcttttttgt
    11941 aaatgcttta ttttttattt ttctgtctat accattctat aaaacctata atacgtgtgt
    12001 tcccttctat aattttctcc taaaaattta tttttttaag cttttttcta tgaaatattt
    12061 tcttttgtct attgacttgt gcaatcggtt gcgtttatta tgaacgtata aaacagctca
    12121 ttaggaggag aaaaatgaaa cagatcaaac gactatttgc tattgatcca tggaaaatca
    12181 gcacgacaca attagataaa aaaaatcttc gactgcaaga atctttaaca agtattggaa
    12241 acggttatat ggggatgcgc gggaactttg aagaaactta ctcaggggac caccatcaag
    12301 gtacttattt ggcgggtgtc tggtatcccg ataagacacg tgtcggctgg tggaaaaatg
    12361 gttatccaga atactttgga aaagtgatca acgccttgaa ctttatcgcg atagatattt
    12421 cgatcaacga tcagctgatc gacttggctt ctttggaacc agaagacttt tactgggaat
    12481 tagatatgaa aaatggtgta ttatctcgta cattcacaat cactacttct actaataaag
    12541 tacgcatttc cttcgaacgt tttctgagca ttgtcaaaaa agaatcagct tatatctatt
    12601 taactataga aatgcttgaa ggtagcggaa cagtcaaact cgtatcaaaa ttggatggaa
    12661 atgttcaaaa cgaagacagc aactatgatg aacatttttg gaatgagatt gatcgtggaa
    12721 ctatagaaga aatcggctat ttgacgacta aaactattcc aaacaacttt gggattgaac
    12781 aatttactgt tactgcagca atgcgccatt tcgttaatgg aaaatcagtc atccctgact
    12841 atcacgaaga tactttagca ttacatggtt gcttgtctgc agaattatct caaggtgaga
    12901 catggtcagt ggaaaaagaa attatcgttc ttactagtag agatattcca gaagcgcagc
    12961 aagcagaaaa agctgtctca gaattaacga accagacaaa caattatatc caagcaaaag
    13021 aagagcaaac agcggcttgg gcagaacgat ggaagcttgc cgatgtggtc atcgaaggag
    13081 acgaagaagc acaacaaggt attcgattca atttgttcca actattctct acttactacg
    13141 gcgaagatga acgattgaat atcggcccca aaggattcac aggagaaaaa tacggcggag
    13201 ccacttactg ggatacagaa gcgtatgctg tccctcttta tcttgcttta gccaaacctg
    13261 aagtaactaa gaatctgctg aaatatcggc ataatcaact gccgcaagca atccacaacg
    13321 ctcagcaaca aggattaaaa ggcgcgcttt atcctatggt caccttcact ggtgtcgaat
    13381 gccataacga gtgggaaatc acattcgagg agattcaccg aaatggcgcg attgcctatg
    13441 caatctacaa ttatacgaat tacaccggcg atacggaata tttgaaaaat gaaggactgg
    13501 aagttttagc agaaatcgca cgcttctggg cagaccgtgt ccatttttca aaacgagcaa
    13561 ataaatacat gatccacggt gtgaccggcc caaacgaata tgagaacaat atcaataaca
    13621 attggtatac aaatacgatc gcagcttggg tcttgcgtta cacgcgagaa aattatttaa
    13681 cttatcaaaa agaagctgct atcactatca gcgaagaaga actagccaaa tggaaagata
    13741 tcgcagagaa catgtacttc ccagttgacg aagaattagg aatctttgtc cagcatgaca
    13801 cattcttaga taaagatctc atgcctgtat ccgatattcc cacaagcgat cttcctctga
    13861 atcagcattg gtcttgggac aaaatcctta gatcttgctt catcaagcag gcagatgtac
    13921 tacaggggat ttatttcttc aatgatactt ttacaaaaga agaaaagcaa aaaaactttg
    13981 atttctatga accaatgact gtccatgagt cttccctttc gccaagtatc cattcgattt
    14041 tagcagcaga attaggaatg gaaagcaaag ctgtagaaat gtaccagcga acagctcgct
    14101 tggatttgga taattacaat aacgacacag aagacggctt gcacatcact tccatgactg
    14161 gtagctggtt gtcgattgtc caaggatttg ctcaaatgaa aactgcccat gatcagttga
    14221 gattcgcacc atttctgcca aaaacttgga aagcttattc tttccatatc aattatcgcg
    14281 gacgtttatt gttcatctca gtcacagatg aacaagttac tttcgagtta ttagaaggtt
    14341 ttcctctaga aatttacgtc tatgaacagt cttattcttt agcggatcgt ctagaaataa
    14401 cgctaagaaa ggaggaagca aatgtttaaa ggggtattgt ttgatttaga cggtgtcatt
    14461 accgatactg ctgaattcca ttatcgtgct tggcgaaagc ttggtcagga aatcggcatt
    14521 acgatcgacc acacattcaa cgaacagcta aaaggcgtca gccgagaaga ctcactctct
    14581 ttgcttttag cttatggcgg aaaagaacac tctttttcaa aggaagaatt tgcagaatta
    14641 gcgaaaagaa aaaacgatta ttatttagag atgatccaga cgatcgaacc aaaagatgtc
    14701 ttccccgggg tcgtgccttt actggattct ttaaaagaag aaaaaatcaa gattgctctt
    14761 gcttctgcaa gtaaaaacgg gccattccta cttgaaaaaa tgggtcttac accttacttt
    14821 gatgctattg ccgacccggc agaagcaaca aacggaaaac ctgcgccaga tatcttcctc
    14881 cttgcagcaa aagctgtcgg actaaaagca gaagaatgta tcgggatcga agacgcgcaa
    14941 gccggtatcc aagccatcct ctcaagtggc gctcaaccaa ttggcgtggg acgtgctgaa
    15001 gaccttggag aggagatccc gcttgtccct gatacgactt ttcttacgat cgattacttg
    15061 aaagaaaagt gtcatgacca tggataatcc agagatctcc gtcgtaccag ttccagagac
    15121 tgaaataaag aaaatcacat tgaagaacga ctacttagaa gtcgttcttc tcaattacgg
    15181 tgcccgcctg caccaaatct tcgcaccaga caaagaagga aaatcagaaa atgttttatt
    15241 gtcttacgat cgtttcgaag atgttctaac agacaaaagc ttttttggag caactgtcgg
    15301 acctgtagcc ggaaggatcc gggatgcttc ttggggtgag catagattgg agaaaaactg
    15361 cggatcacac catatccacg gtggcacgaa aggctggtct ttccaatttt gggaagtaga
    15421 agttttcaaa actccatcat caataggtgt ggtcttttac ttaaaagatg aattttctac
    15481 ctatccagga ccaatcactg ctacgatcac ttaccgttta acaaaaaacg aattagagat
    15541 gacaacctct gctagtagcc ttgttgaaac catctgcaat ccgaccaacc atgcctactt
    15601 caacctttca ggaaatggaa caagagacat ctatgaacat cagttaacgg tctttttaga
    15661 tggtgtgctt gaattagatc aagaaaaact gcctactgga aattggacaa aaaaagaaaa
    15721 actgccaatc gactttagaa aatccccaac actgcaagag atccttgcat gttatccaga
    15781 tggactagat gatgtatttc ttttgcatca tcctaggctt tccaaaactt ccttacaatt
    15841 attcgagaag cattctggtc gccaaatgac tatagcaact tctaataaaa gtatggtatt
    15901 attttctacg actggattcg aagctgattt ctctgtcaat ggaaaacaga tgcattcaaa
    15961 ctacggatta gcaatcgaac cgcaagaaat ccctgatatc gttcatttcc ccaaatttgg
    16021 atcgatcaac ctccatcctg gtcaagaacg gatcagtcag acgatttatc ggttctctgc
    16081 acaataacaa gagaaaggtg tttttatcat ggctattacc gtaaaagatg tggcgaaaaa
    16141 agccggtgtt gccacctcga ccgtctctcg tgtcatcaac gatcatccta gtatttccga
    16201 gacaacaaag aagaaagtcc gaaaaattat ggatgaacta ggttatgttc ctaacatgac
    16261 tgcccgcaat ctaggaaaac gcatttccag tgccatcggc gtaatcttac cccctcttga
    16321 ttcaaaagag cggatcggta acccatttta tcttgagatc atggaagcaa tcaacgaaga
    16381 agcgcggaat tatgatatga ctacagcaat cgctactgct aaaaattttg aattgctgtt
    16441 agagaacgtc cagcgtatgc atttacaaaa acaagtagat ggttttattc tagtgtattc
    16501 agatagtcaa gatcctgtca ttgattattt ataccaaaac cacatccctt tcactttgat
    16561 cggacagcct tatcatcatg agaacgaaat cgtttatgta gataatgata accagcttct
    16621 aggtaaacaa gcaacagaat ttttgatcca gaatggacat aagaatatcc tgtttgtgac
    16681 aaacacgact catgaaagtt tgtatttcga acgatatttc ggttatcaaa aagcaatgat
    16741 gatggctggt cttcctgcgt tatccagtgt agtactagag catccggagg attatctgtc
    16801 ctttgagaaa acgttgaaag aaaacgaagc cacagcattg gtggtcattg acgatatctt
    16861 cgcccttcgc acgatgcagt tggcgcaaat gtacggctat gtcattccag agacactctc
    16921 cgtcattagc ttcaacaact cgatcttctc aacattaaca cacccttacc ttacaagtat
    16981 cgatatcgat atctccgaat taggacgtgt cgctatgcaa aagctgcgcg aattgatcca
    17041 tgaagaattg agcagtggcg tacgtttggt catccctcat cgcttgatca aaagagagac
    17101 agtcgttcct ttagaaaacc catactaaat agctgactca ctaaatacgc tgaccattta
    17161 tcctatggtc agctttttat gtaaaagaag atactacttc taacacattg tttatctgta
    17221 aaaaagagcg tgggacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa
    17281 cggcggaagc agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa tttaaaaagc
    17341 aattttcttg agtttcttct tatttcttgg agttaaacgc ttctgtccca gcctcttttt
    17401 tccttccttc aattttttac acgtcgacga ttcaataaaa aaccgcctaa tattgtaaag
    17461 acaggtgcaa gaatcgagaa aaaggcgaat ggcaagtaat gcaacgcgct aactttcatc
    17521 gttcccataa tgaatgtgcc gctgactccc cacggtacga gagaattgac ggtcgcacct
    17581 gaatccgcta gtgttcgtgt caaataggtt tttgataagc caacgtcatc aaaagaacgc
    17641 ttgaatgttt ctcctggaag aatgatggac agatactgtt ctccaacgat cagattgatt
    17701 ccgatacagc tcaaggcagt aaacccgact aaacgagaag gtcggtccat cttttctttt
    17761 aattcttgaa cgatggtatc aacgatcaga tatttgatca gtaacccacc taatgccaat
    17821 gcaagtaaaa tcaaactagc agaacctaac atactcatga tcccgcctcg agaaagcagt
    17881 tcatctagct ttggatcagg tgtatttgcg acataaccat tcatcaagat gtctgctgct
    17941 tttccgaccg tcaaactttt ctcatggata aaagaaagaa cgagagcagc tgtcgatccc
    18001 gctagtaatg tagggatagc cggaattttt ttgattgccc ccccaaataa aataactagt
    18061 ggaatcaatg tccaaggaga gatccaaaag ctcgctttca tgttttggat catttcattg
    18121 atactagcta gatcggctga atgactgtta tgtcctaata tcgtataaaa aatcaacgaa
    18181 aggacgaatg ctgggaaatc cgtataacgc ataccagcga tatgttcgaa tagattaact
    18241 cctccaatac ccgctgccaa gttggtcgta tctgataaag gcgagcagtt attccctaaa
    18301 aaggcaccgg aaacgactgc gcctgtagtc attgcatcat tgaatccaag taaatgaccg
    18361 atccccaaaa aagcaattcc aatcgtcgaa atcgttgtaa atgaactgcc gacagtcact
    18421 ccgacaattg cacaaacaag aaatgctgtc ggtaaaaaga aacgcacaga aacaagttta
    18481 aatccataaa ccataatcgt agggatggtt ccagataaaa tccatgaagc aactaagaca
    18541 ccaatcaaaa gaaaaatcag gattggaatg atccctggag tgattccttt gatgatcccg
    18601 tcatggatct catcccatgt gaacttttta aatctgccat aaaacaacaa acacatgaaa
    18661 gctgcaagga tcgggatatg tggcgagagc tggaatccga tgatcagtac tcctaggagt
    18721 gccaacaaca cgatcaatac agcgatactt tcttttaaag aaatattttt attcatcgtc
    18781 gatctcctat ttcaaatgaa aaggccctgc catgaaaaaa ctattcactt ggcaggacct
    18841 cctactaaat cagcgacaaa acgtcggctg aaagacttat tttttttatt tttcttctaa
    18901 acttttttct acctcaatcc cccaagaatc tttcttgaag tgattgatga tcaatggaat
    18961 aacgaacatg accactgtga tagctgctac taataatgca tcactcaatg tcgctgtacc
    19021 taatgtagca aatacgacaa cgatgataga gaagatcagc atgcagctga ctacccaagc
    19081 taatccgttt ccgtttttac caattcggta aggacgttcg aattctggat gtttcttacg
    19141 cattttaagc aatgaaacag caatcaaaat gtacacgata caataaataa cagttgtagc
    19201 atttgtaagt gtcaagaata cagcacttac gtcatccatt acaccataaa gcaaagcaaa
    19261 taatgaaata acgattgatt gtgttagaac gacatttcta gatacgccgt atttgttttc
    19321 tttatggaat ccgaattttg gtggaaggaa tccttcacga gctacttgga tgattgtttt
    19381 tgatggtcca gtaacccaag ctgataattg taaaagcaca ccaataaata ccatgaagct
    19441 gaagatattt ccgatcactt ctggtaagcc taggatttga cagtcaatca agataggctg
    19501 cgtgatattt gctaattcca tttttccatc tggtacgaca tttgctacaa gcatcgcatt
    19561 gatgacattc aataaaacta atccgatcaa agcgataaat acgccttttg tataattttt
    19621 tgttgcgtct ttcaaacgag gcatgtaaac agaactcatt tcgatcccaa caaaaataaa
    19681 tgtgatacca gctaagtatt tcaatgaatc aatatgttcc aagtcaggga aagcttttga
    19741 ccatgaaaag tcacctagat agccgtttga gactagtccg actttgaagg ctgccaaaac
    19801 acctaaaacg aacatgatga ctactgggat atatacccct agccatacac cgatgttccc
    19861 gccgactttt gccatatcga atttcaagtt caagatcgtg atgatccagt agataactaa
    19921 aatacaacct aaaacgaacc agtgattatt gccaagttct acattaccaa atgtgtttcc
    19981 taacaatggt cctaaagtag aagcgaccat taccatacct gggaacattt gcacccataa
    20041 tagccatgca acgacaaatc cccatttgct gcccagtgct gtttttaccc ataactgagg
    20101 accgccttct tgaggaagca tcgtggaaag ctcaccggaa accattgata tcggaccggc
    20161 aaaaaacaaa actgcaaaaa ttgaataaaa aatcaatgtc caaccgactg cggctaacgt
    20221 aggaatactc cgaaccgttg cacacagtgc cattgtcaga ccgataaagg tcccaagacc
    20281 cattttactt acttcagatt tactcaccgt tgacactctc cttgattttt tggataaaat
    20341 aacggtgtct ttgaagtagt ttcagcaata aacgaaacaa ttcagcgaat atttgagggg
    20401 attctttgag tctattgctt gaagggtttc ttcaaagaca acctcaaaac aaagggatcg
    20461 aagagcttag gtctcccctt gctcttcaga tccaaacatg cgtcagaaac agttagtatt
    20521 caagctgttt tctaacatga ttaccttgct tattttgctt cgcttgccaa taattggtct
    20581 gcgtagattt tttccaattt ttcttgaaga gctgctttga ttttttcagc atattcttca
    20641 aagtgttctt ctttgttcat gtatggtgtc attacgctgg cacgcaatac agttactttt
    20701 ccggcacggt tccattcttc atctgagaat cctagttggt tcacaaattg taatgggctg
    20761 ttgccatagt ctgggatagc aaagtcagta tgtgaagtta agaactcatt accgtaaatg
    20821 cttcctttca cgtatgaaga ataatcatat acgtcatggt tcaatttatt cattgcaact
    20881 aagtcatcgt tgcctttttc tttgaataca tagtctacca tattgaaatc tggataagtt
    20941 aatggatgaa cttcgatttc tttgtctcct actttaaatg acaagtcatt caagaagttg
    21001 tagaaacgat gtgcaccttc gattgatgca cccattaatt taccatatcc tgtgacattc
    21061 aaaggtaaga catggtgtgc tgcccaaacg ctggctgctg ttgcccctgc ttttgaacct
    21121 tccaagatat aagccccaag taatgctggg atatctgcgc ctttttcaaa tacatatgtc
    21181 gcaaagtaag agataacgtc tctcatgcgg atatctttga tgacgatacc accggcagaa
    21241 tatggaacat agcccatttt atgtgggtca atcgttacag attctgcttc ttcgattgct
    21301 ttatatgcac tgtgtacttc ttctaagata taatctttgt tttctgtaaa gacattgtat
    21361 ttgtaatgaa catcttttaa atcttcaaat ggaatgaagt tgttgtcttc gtctaagaaa
    21421 atcgcacggc cgtatccgcc ataagcagca tctacgtgta agtagaagta aataccgtct
    21481 ttttctaata cgcgacgcaa tgcaacgatt ttatcgatac cgtcgattgc tccttcttct
    21541 gttgatccta caacaccgac tacacctagg attggtgttt tttcagctgc tagaccacga
    21601 acgatttttt caagttcgtt gatgtccatg cgatagttgt ggtcaactgg cactggaatc
    21661 acttggtcta aaccgatacc gatgatgtcg gcagctttta gccatgaata gtgtttagtt
    21721 tgtggaacca accattttcc taatttttct aaatgttttc cgctacgtgc tgagtgagct
    21781 ttgatttcgt cgattttttc tgggacgctg tctaacagat tcatgatttc ttctgttgac
    21841 aagttcatta attcccaatc gctttttcca gcaactagtt caggtgtcac ttctttcatt
    21901 gcaagcggca atgatttgat gttgcgggca taccaaagtc cttctaagtt tgctaaagaa
    21961 ccatcagcaa cgatgtggcc ccagccatct ttatagctca ttaattttgc aaattccatt
    22021 cctacttctt cttccatttg gcttgttgca ggagaagatt cataggcaac gttattacca
    22081 ttccatagca tagcaaaatt gtacgctagt aaagatggca tcaatgtttc agagttcata
    22141 tgaccccagt aacgtccggc attatgccaa ggaacggaat gggtacgcat ccgcgctgaa
    22201 atttctgata gaacatcctt tgttttattc acagtgtgtt caaaactagc actgcttttt
    22261 tcttctggcg taataatagg catgtcttga ggcatgtagt tttgacgcca gcctaaatgt
    22321 tcatccacca attcattcaa caaagcttta tagatttggc cgttctcagc tttgtcccca
    22381 atgaataggg catttaggtt tagatctttc gacaatgatt cactcatagt gaaaccctcc
    22441 taaaaaaata tttaaatttt gtcgagccct acattacacc tgttcttcta ttctgtaaac
    22501 taagttttgg cctgattttt aatcatattt taatatgtat caattatccg aattgttcgc
    22561 acttttgaaa taattaaaaa aaacgaggga atttacaaat gtaaactccc tcgcaaagat
    22621 tgtattaacg acaaccagcg ttctatttta ggatgggttt caaaattgga atgttgtaat
    22681 agtatttccc tttttcaagg taaaaactta ctaaattcta atcaattact ttggccaaaa
    22741 agtaattttt cttacctttt cgaataacca caaacttacc atcgaattca tcggatggat
    22801 ttatgacaaa atttaaatcg gtaacgcggt caccgttaat acttatagct ccgtttgaaa
    22861 catcttcacg tgcttgacgt ttagatggtt caatttttgt ggaaacaagc agttccacga
    22921 tattttcagg tgtgcttgaa atttcaacgt tcggcatttt accgaatcct tgcgcgattt
    22981 cttccgcatt tagttcttta atatttccag agaacaatgc ttgcgttatt ttttgcgctt
    23041 ctttcaagtc ttcttcacta tgcacaaatc ttgtaacttc ttctgccaaa cggcgttgtg
    23101 cttcacgttt ctcaggttct gtctctactt ttttcgctaa gtcttcgatt tcttcttgag
    23161 acaagaaagt aaagaatttc aagtatttca ctacatcgcg atcatcttga ttcaaccaga
    23221 attggtagaa ctcaaatggt gaagttttct tcggatcaag ccaaacggca ccgcctgcag
    23281 tttttccgaa tttcgttccg tcagccttca gcatcaatgg gatcgttaaa ccgaacgctt
    23341 ctacttctgg tccttctaat tttcggatta ggtctaatcc agctgtgata tttccccatt
    23401 ggtctgctcc accgatttgc aattgcacat cgtatgtttt atgcagatgc aaaaagtcga
    23461 tagattgcag aatttggtaa gtaaactctg taaatgagat tcctacttcc aaacggctgg
    23521 caacgatatc ttttgctaac atcgtgttga tgttgaagtt tttaccgtag tctctcaaaa
    23581 attcaagtaa agagattttt gacaaccagt cgtagttgtt cacaaatgtg atatttgcat
    23641 ctttaccaaa caattttctc atttgattgg aaagtgcgtc cacgttatgt tgcacttgtt
    23701 ccatcgtttg caacacacgt tctgttttgc ggccgcttgg gtcgccgatc gttcctgttc
    23761 cgccgccaat cagaatatat ggatgatggc ctgccaattg gaatcttttc atcatcataa
    23821 atggaatcaa atgtccgata tgcatcgaat caccagttgg atcaacgccg caataaagtg
    23881 aaatgctctt ttcttcaacg agctcgcgaa gtctttcttc gtttgtttgc tgattaatgg
    23941 cgtcgcgcca agttaattca tcaataatat tcattttact gacctccgtg tagttttttt
    24001 atgaaagcag gaacctgcta gcatgtgtaa ttaattattt cttcaggata ggataggaaa
    24061 taaaaaaagt cccttggcat ataagccaag ggacgaaatc tcgcggtacc acccaatttg
    24121 tatgtctaga tatccaacat acctctcgaa catttaacgc tgtcgcgtgg caatcactgc
    24181 caaagactcc tgaaatgtaa ttcgctttaa agcatgtact ggtttgcagc gaccaccagc
    24241 tttctgaaac attggcttta acaactactt cgtttcgatc ttcgtcttgt tattattaat
    24301 atgtgtctat catagagcgc aactttttct ttgtcaacag aaaaaggata ttttttttaa
    24361 attcctcatt ttttcttttt tgaatccgct ctaattccga acattttatt ttcaattatt
    24421 gttaaaagaa ataacttttt ctgtattttt tctgcaattt atcgagaagt cactttactt
    24481 tgcctcttat tctttcttcg ttacaataag gaatgggaca agtaaaaaaa tgaaaaagca
    24541 agggacgagg tatatggaaa aaaagcaaaa aattatttta ggagccactt ctgctttaac
    24601 tatcgttatt ttaattctaa gtttgttttt tgtcatccga tcatctacaa aaaaagaacc
    24661 aatcattcct gaaaaaaaaa taacagaaaa agcaaaagaa ccgacagatg ataagcaaca
    24721 actagttact caagcaaaaa atctggctca aagctacgat tatgaccaag cgattgcgtt
    24781 attggaaaaa gatagtaaga acggatctac tgaaacacaa cagcttcttc aaacactaaa
    24841 aaaggagaaa gaacaactga tcgactggtc tgatcctact cagatctctc atgtcttttt
    24901 ccacagcttg atcgtggacc cgcaaaaagc cttccactct caacaggcac aaggatacaa
    24961 agattatatg gtgactgttg aagaattcaa ccgttcgatc gaacaacttt atcaaaatga
    25021 ttttgtttta gttaatttaa atgatttgat ccaaaaagac gaacaaggaa atctttcctt
    25081 taacgggctt gcgctacctg aaggaaaaaa accattggtt ctttcacaag atgatgtcag
    25141 ctattatgaa tatatggata attccggttt tcctagccga ttggtcgtat caaataacaa
    25201 tgaaatcaaa aatgtctata aagagaaaga taaagaagaa atcggtgact ttgacatggt
    25261 tcctctgatc gatgcctttg tcaagaaaca tcctgatttt tcttatcgag gcgcaaaagg
    25321 taccttggcc ctgacaggtt acaacggagt tttaggttat cgaacatcaa aatctcaata
    25381 tggagacaat gaaaaaacaa aaaaagagat taaagaagct aaaaaagtgg cggaacagtt
    25441 gaagaaagac ggctggagct ttgcttccca tacatggggt cacttgaata tgactcaagc
    25501 ttcactagaa gatgtaaaaa aagacaatga attgtggcag caagaagttg cacctatcct
    25561 aggaaaaaca aatattctga tttatccatt tggtgcagac atcagcgact ggcagcctta
    25621 ttcagcagaa aatcaaaaat ttgcttactt gaagagtcaa ggtttcgata ttttctgtaa
    25681 tgtcgatgct tctacaccag cttggggaca attaggtacg gatttctatc gaaatgctcg
    25741 gatcaatatc gatggcattc gttttcaatc tgatttagac ggaaaaaatc ctattcttga
    25801 tccattcatc aatgtccatg atgtctatga caaagaagca cgcgaatctg cttgatttta
    25861 cgtcatttat gaaccaaaaa agccgaactg acattttatc gtcagtttcg gcttttttat
    25921 gctttatttc ttcttcggtg cgattccctt gatcaggact tctgtccatt ctgctgtata
    25981 tggaagcagt tttgcgtata tctccggctt agaaattcct tctaccattg cttgaaaata
    26041 gaggatcaag aactcatccg aatatttcaa atccactttt ccttctttcc gccctcgatg
    26101 gaaaagatca agcatgatac tgaaactttc ttgcgtatac gcatccatcg cgtcagaaaa
    26161 ttcttttttt tctttttttg tatagtatgt catcaaatcg atataaaatt gtttgttcac
    26221 tcgattgaga taacggattt tgttttcact catggcaatc agtgtttctt caaatggaag
    26281 attttccgca atcaacgctt tcgcttcttg ccctaaatca ttcataaatg caaaaaatac
    26341 ttcataaatc agcccttcct tgctgccaaa atatttaaaa atcgtcgctt tacttacctg
    26401 agcgttctca gctaccttat ccattgtcac tccagcggtt cctatgtctg tgttcatcaa
    26461 gtcaaaagct gcttgtaaaa tctctttctt tttctcttgt gctctctttt caaaaccgtt
    26521 catttgtaga gcctcccgta attttaaact tttataatat atatagttca aatttattct
    26581 gaggtttatt ataactatct attgagaaag tatcaagcta gcaattcctt gtttatgaat
    26641 tcattgacag aaatttataa aaagaatatt atgtactaaa ataataaaaa aagttttata
    26701 aaaaggtata aaaccttttt attaaactat ttaatcttgt ttagtatata tttttagaaa
    26761 aaggagtggg gtttttatgg cagaaatcgt caaagtcaca catttgaaaa agagctttgg
    26821 tcgtttcgaa gctttaaaag atgtctcttt caccgtacat tcaggtgaag tcgttggatt
    26881 tatcggacca aatggttctg gaaaatccac gacgattcgg acacttttag ggattataaa
    26941 aaaagacggc ggaacggcaa cgatttttgg gcaagatgta tgggaagata gtttatctat
    27001 ccatgaacgt ctttcttatg ttccaggcga tatctctttg tggggaaatt tgactggagg
    27061 agcgatcatc gatctcttca tgaagcttca tggaaaaggg agtgctcaaa aaaaagatga
    27121 actgattcaa cgtttctctc ttgatcctaa gaaaaaagca aaaaactatt caaaaggaaa
    27181 tcgccaaaaa gtgggcttga ttgctgcttt ggctgttgat tcggatctct atttatttga
    27241 tgagcctact tctggtttag atcctttgat ggaaacgatt ttccaagaag aagttgaaaa
    27301 attgaaagaa cagggcaaat ccatcctact ttcttctcat attctcagtg aagtcgagcg
    27361 actagcggat aaagtcgtga tcatacgcga aggaacagtc gtagaagaag gaacactcga
    27421 tgaattgcgt catttgactc gttcgaccat cactatagaa acagaagcag agaatagtca
    27481 cttagcacaa ttgaacggtg tccatgactt tgtgcaaaaa ggtcacctcg ctcaatttgc
    27541 tgctgataac gaagctttcg atgtgatttt agctgaagcg tccaaattag gtgtgaaaaa
    27601 atttgaatct attccaccga ctcttgagga tttattcatg agacattatg aaggatgagg
    27661 aggaagcgaa atgactgata aattttcacg ctggtccacc cttttttctc aaaaccttag
    27721 ccgtgactgg aaaaagatcc tgatatggct agtcggtgtc actgcttttt ctggtggttt
    27781 tgtccctgcg tttgaagaat tgacttccgg acaaggatta gctggattat acgaaacctt
    27841 gcaaaacccg gcaatgattg caatggtcgg accaactcca gcttcgaatg ctgctgagta
    27901 tactttagga gcgatgtatg caaatgaaat gttgcttttt tgcagtttgt ttgctgctgt
    27961 gatctctgtt ttacacgtgg tgagccaaac gagaaaaaaa gaagaacttg gtctgattga
    28021 acttattcgt tcctttcgag tcggacgtca agcaaactct ttagctgtca tcgctgaaag
    28081 tattctgatc aatttgcttt tagcaatatc gatcagctgt acgatgattt ttttccaagc
    28141 agattcgatc actgcagaag gtgcttggct ttttgggcta tctgtaggta gtatggggat
    28201 tttggggagt gccgttgcac tgtttgctgc acaactgatg ccaagttcag ccagttcgaa
    28261 tggtctgtct ttagcgtttt taggtggact ttaccttcta cgagcaataa cagatgtagc
    28321 tgattcctcc ctttcgatgt ggaatccttt aggctggtct tatttgacct atccatttac
    28381 aactaacaac tggattcctt tgctttattt gtttttgttc agtctaatct tgataatcag
    28441 ttcatttgtt ttagaggaac atcgagattt gaacaccggc tatatccccg aacgtgaagg
    28501 aaaaccgtat gctaaacgtt ctcttttatc cttgcgtggt ttattattct atctaaataa
    28561 agggatgaca atcagttggc ttatcacttt tggtttgatg ggggcggcat acggctctat
    28621 ctacgggaat atgcaacagt ttttagaaag taacgactta atgaaacaga tgtttatcca
    28681 atctggcgtc tcaattgaaa aaaactttac aagcacgatc atggtcgtct tgatttgtct
    28741 agctgctatt ttaccaattg ctagcatcaa tcgtttattt acagaagaaa cccacggacg
    28801 tatgaatcag ctgttcgcaa caaaaatttc taggaaccaa ctttattgga ccaatatgtt
    28861 actagctatt ctatttgcta tattggcaat cctgattagt tctggtgcac tagggctttc
    28921 tgctttggct tcgatgaagg atgcgaaaga catggatcta ttgatgtttc ttaaagccgg
    28981 gttcaatttc ctgcctgccg ttttagtgtt tatcggaatt agtggctttc tattcggatg
    29041 gcttcctcga atgggtaaac ttgcttatat ctacttagct tactcctttg cactcaatta
    29101 ctttggcgga attttggatt taccagaatg gttttccaaa acagctgtcc ctagctgggt
    29161 tccacggatg ccaaacgatt cttttgatct ttccgtgttc cttacgttat catgtatcag
    29221 ccttgcactg ttcgtccttg gttctattgg ttataggcga agagacttac tagaaggata
    29281 ataaaaaagc atgtacaatt tcatgctagc ctccaaatct gggtcaaaaa tccaacattt
    29341 ggaggtcatt tttttattta caagtcttct aactgctctt tatcaatgat ccagacttct
    29401 cgattctttc tttttacata accattctcc tctaataatt taaattttct agataaagtt
    29461 tcgggggtcg taccgataaa tgcagcaagt tctttcattt tcattggcag gaaaaagtga
    29521 tccttccctg tcgctttagc taagtcaagc agatagacag cgactcgttc ttctactttt
    29581 tccatcatca aaaaagttgt ctgctgctgt acttttgtta atttctcaac gttgattgct
    29641 aaaagtttca gactaagggc gggataatgc agtaagagtt ccgagaaatc tttttgtctc
    29701 aatatgcaaa tttccgtttt ttctagtgct tcgccaaata aagactcatt tggaacgcct
    29761 agcaactggc tctctccctc atatccgccc ggctctatta ctcgtaaaag ctgttccttt
    29821 ccgctagcag ataattgata cactttcata ctgccggagg ccacgatcac taattgaggt
    29881 tctccattcg gcgcaagaat ctgttctcct ttttccacat agtgatgttt gacaagtgcg
    29941 tgtacttttt cttgatcttg ctgtactaag tgattgaaca aaggaacaaa tgaaacacat
    30001 aaatgatcat gactcataat ctctcctcct tctaaacagc tatttctaat aaagaaacat
    30061 aacttccctt attccaactg ataattttct tttatcatag cataaacgtc aagcgaacca
    30121 gataccagca aatagagtgg atttcttttt gtcccttgct ttattttcct tcttttgaga
    30181 ccttaagtaa ttgattccta tcaatttttt aaatatttac tttttgaata atcaaaaaca
    30241 aaccttcact cgcaagccga gagtaaggtt tgtttttcgc attgcttatt tcgtgttgtc
    30301 tattgaaatt tttccgcacc tagcttttga tatagtggtg ctagttcttg taaggtttca
    30361 gcggttattt gctcaacgtg ttcgatttct tgcggataga agaatagttt acccatttga
    30421 aaggttcggt ctctcatcgc ttttttcaac tcttcttgtt tctttgtatc ggacaaatag
    30481 tcagacaaag ctaagtggtc gtcaagttca tgttctggtt gcggccatat gtaataatcc
    30541 ttgatatcga ctgttttgct ccactctttc agtatcgcaa gcaactggtt atacgctgca
    30601 atgctaccat atcgttcttc gcttttataa tgttggtaca tcaaatagat ttggtattgt
    30661 ttttgattca acaaaactgc tagacaggca ttctcgtctt gacgagattc gcttcggtac
    30721 gcgctccaaa aatgactgcg taaattccag ccattcgtcc agctttcgat tttaggtttg
    30781 ctcatgccgt acatatcagg caaaagtgca gctgtctgga gctgaatctc tttccatttt
    30841 tgccagtgtt ctttatattc tttcttgatt tgttcaatct tatctgttgg atggctctct
    30901 ttgagctgtt tgaatgcgta gattggtcga tcaaacaact gataatctga ttttccaagt
    30961 tccattgttt cgcctctttc cgttatcttt tgtattctac ctgaattttg cgatatggac
    31021 aaatagaggt tgtgaaaaag ctgttctgca tcaagtcata agaacagcca aacaaaaaac
    31081 tgcgatgagc atcaccgcag ttttattgaa cttaaggttg attgatcaca tctaaaagcg
    31141 ttgaaaataa aatggcacta gaagcagctc ctgggtcgat atgtccgatt gcacgctctc
    31201 ctagatagga agctcgtcct tttttagcta ccaagacttt ggtgtgttct tttgcctggt
    31261 caatgatttc ttttgttaaa ttccctgcct tcaatgcctc tgtgactggc agccaaacat
    31321 ctaacatcgt tttatcgtca gcttctgcct ttcctcggct ttgaataccc gctgttccct
    31381 gctcgatcac ttcgcctaat ttttcttgag aatcaataga atcgacctct tttgtcgctt
    31441 tcatcatgtt catgaatgca gatccgtata acggaccaga agccccaccg actttcgata
    31501 tcatcgccat agagaatact ttgaatgtat cgctgattgt ttcaggatga tcggcttgaa
    31561 aagcttcttc ataagctgaa acccctcttc ccatgttatt tccatggtct ccatcgccaa
    31621 tcggggtatc tagatcactg agatattgtt tgttctgatt gattgcctct gcaaattgcg
    31681 tgagccattc ttggatttct tgaacggtta gtttcatatt atcacccttt tatcttgaga
    31741 ttttttacca tgaaatcgtc tgtacattgc tttctaaaga atctttccat tgtgtctccg
    31801 tcaagtcgat cagtgttaga gaaagacctt gcatatctag tgaggtcata aaattaccga
    31861 cttttcggaa aactacattg acgcctcttt cttccaacag agctaaaaca tcattcatga
    31921 acacgaactg ttccatcaaa ggcgtcccgc ccattccgtt gactagtaca cctgcttctt
    31981 ttggtaaatt cgagtaatca tctaaaatct tagtaacaag ttcctttgcc agtactttag
    32041 aaggctgcat cttttctcga cgatagcctg gctcaccgtg gataccaaca ccatactcga
    32101 tctcatcttc tcctagttcg aatcctggtt tccctacttc tggtacagtt gctgctcgaa
    32161 gcgctagacc gatcgtctta gttgcctgta cgaccttttc tcccagttct ttcaactcag
    32221 ctagggaagc accgtttctt gctgcatcgc ccacgatttt gtgtacaagg acagtacctg
    32281 caactccgcg ttttccagca gtatacgtac tattttcaac ggcgatatca tcatctacga
    32341 tcacactttc tacttcaata tcgtccatag cagctaattc ctttgccata tcgaagttca
    32401 atgcatcccc tgtataattc ttaacgatca gcaaaactcc ttttccacta tccgcttcct
    32461 taatagccgt ctgaatctga tctggagttg gagaagtaaa cacatcacca agcaccgctg
    32521 cacttaacat cccttcccct acaaacccgg catgggatgg ttcatgtccg cttcctccac
    32581 cagaaaccaa accaacttgt tccgctttct gattcttggc tacaacacgg gaagattcta
    32641 cacgatgaac aagttctgga tagcttttta ctaatccttc cagcatttct tcgacaatat
    32701 tgcttggatc attcatgatt tttttcaatt tattcccatc ctttctttcc ggcattttgt
    32761 gcttctgtta agatttgctg agtatcatct gttataccgg cagtgatggc tgctgcaaaa
    32821 gctccttcca ctaaaggcgc atccaccaga tgataacgtt gctgctgctc ttcttccaac
    32881 atgtcttttg ccagttccga gttcaatacc gcgctaccga tatccgcaaa aacaaaataa
    32941 ctagctgcat cgcttgattc attgactgct tctacgattt tcatcgggtc tgatccgatc
    33001 tcgccattta ttccgccgag agaaaaaatt tgcacctctt cggatttttg catctgctca
    33061 atcatttctt taataccatc tgttactttt tgactatgag aaataagcaa aatacttttt
    33121 ttcacaagaa tcttcctttc ttttacatag ttgctaacga ttggtttcgc tttcattaat
    33181 gaacaattca agtatataat aaatttctaa ttttgggaag atatgtgtag tgcttcttga
    33241 agtttgttat actttaatta aaagagagga gtgatcgaat gattacaaca acaacgaaca
    33301 gtgtagaggg aaaagccgta gtagcttata aagggatcgt ttttggtgag gtcattactg
    33361 ggatccatgc atttaaagac ttggaggcgg ggttgcgaaa tatctttggc ggccgctcaa
    33421 aaagctatga aaacgaacta atgggtgcaa gagaagaagc acttgccgaa atggccgaac
    33481 gtgcaaaagc attaggagct gatgcgatca ttggcgtaaa aatggactat gaagtattag
    33541 gcagcgacaa tggcatgctg atggtcacat gtagtggaac agctgtctcc acgagataag
    33601 taggggacat ctgttttaat aactaaagag agatgggaca tgtagtggca ctcaagaatt
    33661 agatttttca gtctaacttc gaggtactct accttcccat cctctctttt ttatttcttt
    33721 ttgcggatga ttccgtaagc tgctgcgact aacacacccg cccctgctaa ggaataactg
    33781 acagaagctg ttttttcatt tgtttttggc aaagtctgac ttgttgattt ggatggctct
    33841 gtcgtttgct gaactgtttc tgtcgtgctt ccagaggtca ctgatttttc tcctgccgaa
    33901 tgcaaaatat cttttattcg ttggaaacta gctgctaagt cagctttttt tgcttcaaaa
    33961 tcattagcaa ctgtttgtgc ttcgctgatc tttccgtgga ttgcttgact ggccgctgtg
    34021 atatccgctt gagtttgact tagctttcca gaagctgttt gagcaacctg atttaattgc
    34081 tgattgaatt cttttgcttg ttggatcttc ccgtcaagat ctgtttggac agcttccgct
    34141 tttgctttcg cttcggcaag ctttttctca agttgtgcac ggtcatttcc cactttattt
    34201 ttaagatcag ctaaatcttg atcgattgct gcttggtctt ctttcaattt gttttttgca
    34261 gcttctaatg cttcttcgag ttcttttctt ttattttcca agtcttgcaa atgatcgatt
    34321 tggtcagaag aggtagaact atttattgat gtatcttctg aagatgaaat cgtttctcct
    34381 gaattatctg tcggtacatt ggaagtcatt tctgtttccg aggcaccgtt ttcagcacca
    34441 gaagagctta tagttgttga aggttctgtt tgagcaggtt cagaagtttc cgcaaaagct
    34501 gtctgtccca ataagaaaat actggaaaca gcaattggcc agattaacgg cttcattctt
    34561 tttttcatca cttttcccat ccttactact ttttaactaa tttcttatta taagcaaaaa
    34621 tgtttggaag aaccataaac acaacaggct gtttgtctaa aaaacggtgc atcttttatt
    34681 tttttgtacg ttccgggctt ttccatgtcc cgcttccata acctaaaatc gttttgactg
    34741 ctggaatgaa agtcgtcacg atcgttatcg cgttcactat ccagaacaaa agcatatata
    34801 gtggtgcgaa aagaaggtat ttcaattttc ttcgtcgatc atctacaatc agcgaagcta
    34861 gcaactggaa aaatcctgcg accatttcaa agcagatgaa cacaaaactg aatgtaaaag
    34921 taatataaat ctgttcgtag tttccttgat atacataatg cccgattaat ccagcaaaaa
    34981 gaactacgga aatacaaaag aatattgacc agacaatact caatgtttga tcaatgaaga
    35041 tgatcgttct tccaatatgt ttaaaaggat ggagcatcac ttttttgaaa ttcgtcagcc
    35101 agacttctgt tccacctttt gcccaacgtt ttctttgtcg atatagcatc ttcaacgtca
    35161 caggtacttc catgaaaaag ataatctcag gagcaaaaac agataaccag tcatttaact
    35221 gatgatccca agcaatactg atgtcttctg tcgctcgatc ttgtctgaat ccgcccacat
    35281 cgatcaaggc ttcttttcga tacatcgtat ttgctccact gtacgcataa agaccaccga
    35341 aaacagctga ctgtgttcgt ttaatgatgc ccacgatact tgagaattca accgtttgag
    35401 attttgcaat caatttggta cgattttgga catccatatt tgcagtgacc gcagcaatat
    35461 gtcttgcacc agggcgaatg aaataattca catacctaat cagtgcatct ggctccggta
    35521 ccgtgtctgc atcattgctt aaaatcaatt tcccttttgc aaaggcaagt ccgatattaa
    35581 acgcgtgggc ttttccttta tttttttcga tccgaaccac acgaagatta gcgtattttt
    35641 tcatcagtct agctaatatt tctggtgttt ggtccgttga accatcgtct gtcactaata
    35701 cctcatagtt gtgataattc aatttcgtca tcaaatactc gattgtatct tcgatcacaa
    35761 tttcttcatt atgggctggc accatgatcg tgatgaacgg ttcgacactc aagggaacat
    35821 ctacccattc tttttgctta tgtttgtata aaaacacata acaccagaca ccaataaacc
    35881 atacaaatcc gcctaaaatc ggataagaaa cgagaaaaaa tacataatag acaaacaagt
    35941 atctaagaat aaattacctg tatgggtgat tgagatcatt tcagttccac cccattttct
    36001 ttatacaaat ctgcaatgaa tgtcgtatct agatttttct cttcggagac agaataaaaa
    36061 cggaccgttt ctctctcttc ttttgttcca aaacgttccg tatacacttc ttcaagtaat
    36121 tcttgtcttt ttttcaattt ttcatcttca tattcaaaag atttatttac ttttttgtat
    36181 agatttcgat tgttccacct agtcaataca aatgaggtaa tcaggaaact gaaaaaaatc
    36241 aatacaaaaa agccgattaa gaaatacagc attttctttt ctgataaaaa agcgtacaag
    36301 gaaaaatcct tggctctttc tggtctcgtt aatgggaaaa agacccatat aaaaggaaga
    36361 acaacgatca tccatcctaa aagagccact aacgtttgcc aaatctttaa ccagtaatta
    36421 ccttttgaaa aatacttatc tttcaccaaa attgatgcaa cttcttctct tgttactttt
    36481 ttcatatcct cacctcacgt ttttttgtta cgacgtagga gtttaccata catttcattt
    36541 cttttcacat aaagtgttcc taaatttttc ctaagaaaaa gaacaaaaca tttctcatca
    36601 gcaaatgaaa aatattttgt tctttttatc agttgttctt tttatttttt atctcttaat
    36661 tatgttgctc tttccaatac gacaatgctt ttcattcctc tagatatcgc cgtgtacatt
    36721 tgtctgcgtc ttctttgctc atctccatcg ttttcaaatg gatataagat tacatgatca
    36781 aattccagtc cttttgctag actcaaagga atgatttggc agttttctaa tccatatgaa
    36841 ttttttttaa tcgattcttg tagcgtttgg gtttcctctt ctgtttgggt gataactgcc
    36901 gctttttctc cttttagaga aaccaaaatc tcagctagta ttttcaacaa ttcttcagag
    36961 gatcgaaaag agcggtattc gggttctttt ccttgcggtc ggatcgatac gatgtcgatc
    37021 ttctcttgat ccacagcata ggttttgaaa agctctgtga ttgctccgct agaacggtaa
    37081 ctatttctaa gatcataccg atggatcggc agatggtagt cgtcgaaaca acgcataata
    37141 tcagcaaaag tagtggaaga attaaagatt gcctgattct cgtcacctac taaagtaaag
    37201 tgagtttttg gaaataattc gatcaataga cctaattgtg ccagggtata atcttgtact
    37261 tcatcaatca atagatagcg aaatgctggt acatttacct tttcaacaag taaatgacga
    37321 atagctaata taatgactgc ttcatcaaca gtacgtgtgg gttgccaagc ataagctgag
    37381 ccatatcgtt tttcataaat tctttcaaac aactgatgct catccaccca tgccatttct
    37441 tcgatttgtc tggttatttt tcgatatttt ttttgtaaaa gtttccttgc ataagctaca
    37501 atactttgtt ccgaatcatc agaaatcaat ttaccgaata attccaactg cctatcttct
    37561 gtcaacgaga gtacctgatt ctgcacagca ggactttttg cttgtttcaa aagatgattc
    37621 ttccattcgc tcatcagtgc ctttttcgtt gcttgaagcc tatcgatcaa tttaggatga
    37681 gcaggaactt tctcatatat tttttcgatc gtttttttag aaaggactgt ttttccattt
    37741 ttagtaagtc cacggataaa attcggatga tctaaaaaca aaggatctga ttgttttaga
    37801 ttatcgataa actttttgct acgcaaacgt tctgtctgct ccgatacatt ttctcccgtg
    37861 atacgtttga aataagcctc ttcaccttct atttcctctg ctgaaagctg tgaaaccagc
    37921 tgtatgatgg ttagattcag tggatttctt tcacctaatg atggtaggac attcgaaata
    37981 tagtcgataa accgatgatt aggtgataga atcagcaagt catcggatgt catcgtatct
    38041 cgatataaat agagcagata cgcaatacgc tgcatgatag cagaggtttt accacttcct
    38101 gctacgccat ttaccaagat attttgactt ttcacatccc gaatgattgt gttttgttcc
    38161 gattggatcg tagcagtgat agccttcatt tcattggtct catcttggcc taagacttct
    38221 aataatacgt catcttgaat agctacagac gtatcaaaaa acttgaccaa acgatctctt
    38281 tccaaaagaa attgtcgtct ttctttaata accgtatcga ttttattttg acgaaccgta
    38341 taagaagatg gaccaatcat gttattgtaa aaaagttcgg caattggtga acgccaatca
    38401 taaacaagat tttcatctgc atcatctgtg aaatttgctg taccgatata aaaggattct
    38461 tttggctcat tatccagaaa gtctacaacg acttttccaa agtagggact tttcaataaa
    38521 cgttcgatct ttgctagctg attttctgcg tttttctgtt tgatattcat ctgatcgatt
    38581 tctctatttt tcatttcaat catcgaaaaa gtatccaggt tatctaagta actgtcaaaa
    38641 ttcaatcgaa gctcgccagc catttctttc aacgactggt ttccttctat ttttgccgta
    38701 tccatcgatt cccgcagttc gtttttttta tcaattagct tttgatacac gttcttcaga
    38761 tatgcttctt ctaactgttt ttgtgtgttg accatacaca ttctcctctt tttttaaagt
    38821 ggtggaaccg attagtttac ctcttttaag agtcgaatgc aagcttttta acgagtatca
    38881 tttgttagga tatatcagtt cttcaggtcg gacagtttga tataaagaaa atgcaccatc
    38941 aaggtttttt acgtggtagc cagactgctt caagattctt tccgctagat agctacgtaa
    39001 tccgctatga cagctgacga tatattcttg ttggctgtct aattcattta atcggtcccg
    39061 aagttcattc aaagggatat gtttggcttc cttgaatttg cccttttcca attcttctgc
    39121 tgttcgcaca tctaataaaa tttttccttt tgctagttct gtcggcaatt catgccattg
    39181 tacggtttca ctaagccctt ctgcaatgtt cattgctgca tatcctagca tgtttactgg
    39241 atctttggct gagccaaatg gcggtgcata cgtcaattct aattccggta aatcgaagat
    39301 cgtcaaatgc cctttgattg ctgttgctaa aatatcgatc cgtttatcca caccttttgc
    39361 cccaacacct tgtgcaccat aaatctcgcc agtctctgga tggaagatca acttcagtaa
    39421 aatatctgtt gcttctggat aatagcttgc atgatctttt cctgatacat gaatgacttc
    39481 aaaagacagt tcgttttctt tggctgttct ttcacttaaa ccggtggatg cggcagtcat
    39541 tccaaacgtt cgtataattg ctgttccaat accgccttga tttcttcgag aaattccgga
    39601 aatcgtgtcc gcaacttgtc taccttgacg attggctggt gaagcaagag aaataagtgc
    39661 atcttttcca gtgatttgct gttttacaac gatagcatcc cccaccgcat aaatatcagg
    39721 aatattcgtt tgataacgtt cgtctactag gatacccccg cgtatgccta attcgattcc
    39781 agcggtcact gctagctggt tatcaggacg aacaccaatg gataaaataa ctaaatcagc
    39841 agggatggta cgcccatcat ccagtcgcaa tcgtttcccg tggtcttcaa atccagcgac
    39901 agcatgagaa gtaatcactt ctactccttg atgagacaat tctttttcta taaaagctgc
    39961 catttcttca tccagtgttg gaagaatatg tggtgcttgt tcgatcacca tgacttctaa
    40021 acctcttctt tttaggtttt ctgccatttc caatccgatg aatcctgcac caacgatcac
    40081 ggcacgcttt ggctgttttt ctaatgcatg catcacttta tcgatatctg gtacatttct
    40141 aatagaaaaa acattgtcgg cttctgttat ccctggaatc gatggaacaa ctggttttgc
    40201 accaggagat aaaaccaatg catcgtactg ttcaatgtgt ttttgaccct catgtacgac
    40261 ttctaccgtt ttgttttcgg gaaagatggc tgtcacttca tgatttggac gcacatctaa
    40321 acaaaaacga gcggataatg attctggcgt ttggacaaga agattttccc gttcactgat
    40381 ttctcccgaa agataataag gcaagccgca atttgcaaaa gaaacatacg gtcctttttc
    40441 aaaaacaacg atttctgcat cttccattaa tcggcgaagc cgtgtagcag cagacattcc
    40501 acctgctaca cctccgacaa taacgatttt catcttattt ccctcctact gttcgatcaa
    40561 accattgatt catgccacca cgtacattca ctacatcata accagatttc tttaattctt
    40621 tagctgcttg tttactcctc atccctgatt gacaaatcac atagacggtc ttttctttgt
    40681 ctccatcata tctgtttata ctttgtaatg gaacattttt agctcctttt atatgcccgc
    40741 cccggtattc tgcaggtgtt ctaacatcaa gtaacgctgg attttccaaa agcttttcct
    40801 ttaattctgg gactgttatc gattttattg attgaaatag caaattcatt ttctgcacct
    40861 catttacatt tttataaata cctcatgggg tatattaaac aggagcttta ttaatatgtc
    40921 aaccagaatg actcttcatt tttttcacta ctttttatat ttgcataaaa taccgataag
    40981 gggtattatc taattataaa aatagaggag aatgtgttat ggagattgat aataaaaata
    41041 tcctgaaccg tttgaaacgt acagagggac aaattcgtgg tatccaaaaa atgatcgaag
    41101 acgaaaaaga atgtatggat gtcatcactc aattaagcgc tgttcgttct agtattgatc
    41161 gcgtaatggg catgatcgtt gcagataatc tgaaaaattg ctttgagaaa cctgatagta
    41221 atccagaaga acaagcggct aaactagaac aagcgatcaa gatgattatt aaaaagtaaa
    41281 ggaatgattt caatgaaagt cgttttccat attgatgaat tagaaaaatg gtcagaaaca
    41341 gggaaaaacg taaaaaacct gataaaagct tctccagaaa cgacgattgt cgtatctgta
    41401 aatggcatcg cgattaccgg ttatctagac tctgccaatg cagaattctt agatttgcaa
    41461 ggagtcgttt ttcacgcttg cgccaatgct atgcgtgcta atcatatttc agaaagttct
    41521 ttacctgaac aagtaatcgt tgtaccagca ggtgtccttg atttagttga actgcaatcc
    41581 caaggttatg cttatatcaa gccttagtca gtagaggttg cgacagaagt gatcagcttc
    41641 aagaaatttc ggcttatttt tcgaagaagc tacttctgga aaaccgtgaa tcaaaggttg
    41701 tgaaaacgct gtcctgcatc aagt
//
LOCUS       DACGMI010000021        41242 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.021, whole genome shotgun sequence.
ACCESSION   DACGMI010000021 DACGMI010000000
VERSION     DACGMI010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.021"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(287..649)
                     /locus_tag="IXT46_001249"
     CDS             complement(287..649)
                     /locus_tag="IXT46_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947174.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(723..1103)
                     /locus_tag="IXT46_001250"
     CDS             complement(723..1103)
                     /locus_tag="IXT46_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAQ4947175.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1185..2360
                     /locus_tag="IXT46_001251"
     CDS             1185..2360
                     /locus_tag="IXT46_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4947176.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2437..3021)
                     /locus_tag="IXT46_001252"
     CDS             complement(2437..3021)
                     /locus_tag="IXT46_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4947177.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3222..4220
                     /locus_tag="IXT46_001253"
     CDS             3222..4220
                     /locus_tag="IXT46_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4947178.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4332..4841
                     /locus_tag="IXT46_001254"
     CDS             4332..4841
                     /locus_tag="IXT46_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAQ4947179.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4871..5530)
                     /locus_tag="IXT46_001255"
     CDS             complement(4871..5530)
                     /locus_tag="IXT46_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAQ4947180.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5532..6296)
                     /locus_tag="IXT46_001256"
     CDS             complement(5532..6296)
                     /locus_tag="IXT46_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAQ4947181.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6304..6981)
                     /locus_tag="IXT46_001257"
     CDS             complement(6304..6981)
                     /locus_tag="IXT46_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAQ4947182.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7018..8403)
                     /locus_tag="IXT46_001258"
     CDS             complement(7018..8403)
                     /locus_tag="IXT46_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAQ4947183.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8613..8697)
                     /gene="ffs"
                     /locus_tag="IXT46_001259"
     ncRNA           complement(8613..8697)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="IXT46_001259"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8720..9235)
                     /gene="tadA"
                     /locus_tag="IXT46_001260"
     CDS             complement(8720..9235)
                     /gene="tadA"
                     /locus_tag="IXT46_001260"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAQ4947184.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9342..10199
                     /locus_tag="IXT46_001261"
     CDS             9342..10199
                     /locus_tag="IXT46_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAQ4947185.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10280..10615)
                     /locus_tag="IXT46_001262"
     CDS             complement(10280..10615)
                     /locus_tag="IXT46_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947186.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10682..12052)
                     /locus_tag="IXT46_001263"
     CDS             complement(10682..12052)
                     /locus_tag="IXT46_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAQ4947187.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12130..12666)
                     /locus_tag="IXT46_001264"
     CDS             complement(12130..12666)
                     /locus_tag="IXT46_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4947188.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            12975..14456
                     /locus_tag="IXT46_001265"
     CDS             12975..14456
                     /locus_tag="IXT46_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4947189.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGELIKAVHELYMKKGYENKTKRM"
     gene            complement(14559..15266)
                     /locus_tag="IXT46_001266"
     CDS             complement(14559..15266)
                     /locus_tag="IXT46_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAQ4947190.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15345..15683)
                     /locus_tag="IXT46_001267"
     CDS             complement(15345..15683)
                     /locus_tag="IXT46_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAQ4947191.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(15794..16756)
                     /locus_tag="IXT46_001268"
     CDS             complement(15794..16756)
                     /locus_tag="IXT46_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAQ4947192.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(16771..18102)
                     /locus_tag="IXT46_001269"
     CDS             complement(16771..18102)
                     /locus_tag="IXT46_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4947193.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(18110..18790)
                     /locus_tag="IXT46_001270"
     CDS             complement(18110..18790)
                     /locus_tag="IXT46_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAQ4947194.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(19009..19488)
                     /locus_tag="IXT46_001271"
     CDS             complement(19009..19488)
                     /locus_tag="IXT46_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAQ4947195.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(19615..21294)
                     /locus_tag="IXT46_001272"
     CDS             complement(19615..21294)
                     /locus_tag="IXT46_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAQ4947196.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            21842..23344
                     /locus_tag="IXT46_001273"
     CDS             21842..23344
                     /locus_tag="IXT46_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4947197.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            23357..24019
                     /locus_tag="IXT46_001274"
     CDS             23357..24019
                     /locus_tag="IXT46_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947198.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(24120..24323)
                     /locus_tag="IXT46_001275"
     CDS             complement(24120..24323)
                     /locus_tag="IXT46_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAQ4947199.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(24434..25618)
                     /gene="iadA"
                     /locus_tag="IXT46_001276"
     CDS             complement(24434..25618)
                     /gene="iadA"
                     /locus_tag="IXT46_001276"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAQ4947200.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(25775..27514)
                     /gene="yfcC"
                     /locus_tag="IXT46_001277"
     CDS             complement(25775..27514)
                     /gene="yfcC"
                     /locus_tag="IXT46_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAQ4947201.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(28288..28902)
                     /locus_tag="IXT46_001278"
     CDS             complement(28288..28902)
                     /locus_tag="IXT46_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4947202.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(29508..29885)
                     /locus_tag="IXT46_001279"
     CDS             complement(29508..29885)
                     /locus_tag="IXT46_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947203.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(30185..31066)
                     /gene="galU"
                     /locus_tag="IXT46_001280"
     CDS             complement(30185..31066)
                     /gene="galU"
                     /locus_tag="IXT46_001280"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAQ4947204.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTGALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(31109..32128)
                     /locus_tag="IXT46_001281"
     CDS             complement(31109..32128)
                     /locus_tag="IXT46_001281"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAQ4947205.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(32761..33765)
                     /locus_tag="IXT46_001282"
     CDS             complement(32761..33765)
                     /locus_tag="IXT46_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4947206.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(33778..34827)
                     /locus_tag="IXT46_001283"
     CDS             complement(33778..34827)
                     /locus_tag="IXT46_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4947207.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(34844..35665)
                     /locus_tag="IXT46_001284"
     CDS             complement(34844..35665)
                     /locus_tag="IXT46_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4947208.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(35652..36431)
                     /locus_tag="IXT46_001285"
     CDS             complement(35652..36431)
                     /locus_tag="IXT46_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4947209.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(36448..36918)
                     /locus_tag="IXT46_001286"
     CDS             complement(36448..36918)
                     /locus_tag="IXT46_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4947210.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(36930..37349)
                     /locus_tag="IXT46_001287"
     CDS             complement(36930..37349)
                     /locus_tag="IXT46_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAQ4947211.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(37430..40198)
                     /locus_tag="IXT46_001288"
     CDS             complement(37430..40198)
                     /locus_tag="IXT46_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4947212.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            40398..40622
                     /locus_tag="IXT46_001289"
     CDS             40398..40622
                     /locus_tag="IXT46_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947213.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
BASE COUNT        12237 a         8571 c         6859 g        13575 t
ORIGIN      
        1 ttttttaaat tttttagaaa tgtgatataa catccacttc agaatcaacg ctgttaaatt
       61 tatcatgtat ttcttccttg gtcaactata aattaagcat tactttgtga aatgattttt
      121 cgatcgatta ttattattcg ttatacaacc gttttcaaca tattttgaaa ataaaatgca
      181 ctaaaaaact atctttagca gaacatttca ttgtattttt tggaccaaac aataaaaaaa
      241 gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc tgtattttag aagaaaggca
      301 ctccctctac ttcgtaagtt ccaagaacag agcgcatttg acctggttct tcccaaatat
      361 atccttcgcc taattcttct ctttgattct tttgttcagt ttcaaagaca aacaacggaa
      421 cattttcctc tttaatatgt gtatttgtca attccatcaa actaatcttg ctaacatcga
      481 tatgaactat ttcttttaag aaattaagta tattcgctaa accagtcttt ccttcagaaa
      541 gttccgctaa cgcaaattcc aacttgtcat caattgaatg gaccaaaaat tttttagtac
      601 catcctccaa atgcaacata attgtaccag caactctttt gcttgccaaa atttccacct
      661 cgatcaactt gttctatggc ttacataaaa attctagcac attttcagaa aaaatacact
      721 ttttatttct tattttcttt ccgttctagt tcagataatg cttcttctat ccaaataggt
      781 aactgctccg caatagtggt aaatccgatc ttacgatttt tattcgtgaa ataccttttt
      841 ctgcgatatg gaacagctgg atttgttttt tctaacgttc ttaaagataa actgattttt
      901 ttggaatatt catcaatgtc gatgatctga actgttactg gctgtccgac ttttaacaat
      961 gaatggatat ttttcgtata accggattgt acttctgaaa catgaataag tccttgcgtc
     1021 tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc ctgtcacttt tccttcaatt
     1081 atttgtccaa ttttataagt catctacttc cctctcttcg catttatcat tatactgtaa
     1141 atagctcaaa aaaagaagcg acgaaaatga ctggaggtct taagatgatc gaatttgata
     1201 aacagatttc aagaaaagat acagaaagtg taaaatggga cgcaattgct gagacatatc
     1261 aaatggatga cttacttcct ttgtgggtag cagatatgga cttcttgtct cccggtgggg
     1321 tagctaaagc gtttagtgaa tacatcaaac atggaatctt tggttatgcc actctgtctg
     1381 ataaactata tcaggctatc attcattggg aacgccaaca ccatgctgtg gagttgacga
     1441 aagaaaatat cgtttttaca agtggtgtgt taaccagttt agctgcagca gtacaaactt
     1501 ttacaaaacc aggcgattct attttgattc atgacccagt ttatcctcca ttttcctcta
     1561 ttatagaaac aaatcaacgt cacatcgttc gaagctcttt gctagaaaaa aataatcatt
     1621 tcatcatgga cttgtctgac atggagaaaa aaatcgaaga aaacaatgta aaagcaatga
     1681 ttttatgcaa tcctcacaat cctggagggc gtgtttggag caaagaagaa ttgaaacagt
     1741 taagcgaatt gtgtttaaaa catcaagtga ttctgtttag tgacgagatc catcaagatt
     1801 taactttatt cgatcataca tttacttcca tgctaacgat tgatcctaat ttagatgatc
     1861 tactagttgc ttttacttcc gcaaccaaga ctttcaatct agctgcaatc aaaaattcaa
     1921 tggtatttat caaaaatcca gagatgaaag ctgattttga aaaacattta gtgatgaacc
     1981 aacagcacga aatcaacact tttggactga ttggaaccca agcggcttat gagacgggtg
     2041 gagaatggtt aagccaactg attccttatc tagaaaaaaa tgttcaaaca gttaatcagt
     2101 tttttgaaca gtatcttccg aaagtgagaa taatgaaccc tgaaggaact tacttaatgt
     2161 ggttagattt taccgcctat atttcagacg accaagaatt ggagaacact cttgttcgga
     2221 aaggaaaagt cgtattaaat cctggcatca cgtttggtcc ttccggtcat gggcatatgc
     2281 gcttgaatat tgcttgtcca gaagaaactt tactggaagg acttaatcga atcaagtatg
     2341 ctttagagac aatcgattaa atcatttatt caaaataaaa ggacgagacc ttactaggtt
     2401 tcgtcctttt tcataattac tccgtaccat accaaactat tctgaaattt caattgtttc
     2461 aatcactaca tcatgtacag gtcggtcttg tggaccacgt tgtacatttg cgatttcatc
     2521 tactgtgtcc atcccttcta gtacatgtcc aaagactgta tgtcggaaat ctagccaagg
     2581 agttccgcca cctttatacg cttcaatgat ttctgatggg aatccagcac cttctagttg
     2641 tccaagcata ttagctggca catttgtgtt atttacaata aagaattggc ttccgtttgt
     2701 gtttggacct gaatttgcca tagataaagc tccgcgaagg ttgaacagtt cacgactgaa
     2761 ttcatcttca aaactttcgc cataaatact ttcgccaccc attcctgttc cagttggatc
     2821 gccgccttgg atcatgaaat caggaataac gcggtgaaaa atcacgccat cataataacc
     2881 ttttttggaa agttcaatga aattttgaac cgtcttcggt gctagttcag ggaataattg
     2941 aacagtaatg tcaccacggt ttgttttgat aacagctttt ggtccttttt cactttttaa
     3001 atctagttgt gggaatgcca tattgtttcc tcctaatatt tgcatacttc ataataataa
     3061 taacataata cctaacctct cgtaaaaata ctagatttgt tttcttttat ttttcatcac
     3121 tagatacatt ctataactta ccgtttcgat ttcgaattca aacatttttg agaagcattc
     3181 tcaattaaat tctgctatag tgtgaaaagg gaggaatttt tatggaaatc tatgacatta
     3241 caatcatcgg tgcaggtcct gtagggatgt ttgccgcttt ttacgcagga atgcgccaag
     3301 ctaaaacaaa aatcattgac agtctacctc aacttggtgg tcaattagca actttgtatc
     3361 ccgaaaaata tatttacgat attcctgggt atccagcaat aaaagcaagt gaattaatcg
     3421 atcaattaga aaaacaatta actactttta accatacatt ccatttaaaa gaagaagttc
     3481 tctcgcttac tcgtgaagac gaagttatcg agattactac aaataaaggc atccattatt
     3541 ccaaagcagt cattttagct ttaggaaatg gttcattcca gccaagaaaa ttgaatttag
     3601 ataatgctga atcatttgaa aaccacggat tggattattt cgtgaatgat ttgatgaagt
     3661 atgctggaaa aaaagtcgct attgctggag gtggtgattc tgctatcgat tggacgttga
     3721 tgttagagcc tattgcaagc gaagtttact tgattcatcg tcgcccggaa tttcgtgcgc
     3781 acgaacatag tgtatcacgc ttgaaatctt catctgtcaa cttgcttact ccctatctca
     3841 tcgatggatt atcaggcaat aatggggaac tgacagatat ccggttaaaa aaagtgaaaa
     3901 gtgacgagac gattgatttg atgattgatt ctctgatcgt caattatgga ttctcttcta
     3961 atttagaaca tctttcttct tggggacttg atagtaccag aaatgccatt actgtaaaat
     4021 cagatatgtc tacttctatt ccaggcgttt atgcagctgg tgacatctgt acctatgaag
     4081 gaaaagtgaa actgattgct actgggctcg gtgaagcacc tactgcagtg aacaacgctt
     4141 tacactatat taatccaaag gaacgaactc agcctggtca cagcacaagc ttatacgata
     4201 aaaatcttcg tcctagttga ttttttatat ctctttgcat ttcaagttaa acccgaaagc
     4261 agtttcttgc atttttttca tgttccgtta acatgaaata gagaaagaaa aaataaaggg
     4321 ggagcaataa tatggtcgtc aaaactgaga ctttagaaga aaaggcaaga gaactattga
     4381 aggaacgtgg cgtaactgta gaagatatcg cacaacttgt catgttttta caaaaagact
     4441 atatttctga tttgactttg gcggattgta ctgaaagtgt caacagcgtg ctaacaaagc
     4501 gtgaagtaca taacgccatt atcactggaa tccaattaga tatattagca gaaaagaaaa
     4561 aattgatgag tccgttgcaa catattatcg aagatgacga aggcctttac ggtatcgatg
     4621 agatcctagc cttgtcaatc gtgaatgttt acggtacgat cggctttacg aattatggtt
     4681 atatcgacaa ggtgaaacct ggtattttaa aagaactaaa cagccacgat ggcgttcatg
     4741 tccatacctt cttagatgat atcgtcggag cgatcgccgc tgctgctgcc agtcgattag
     4801 cacacaaaga accagaaaaa agaagtcgcc ttactcaata attcaacaaa aaaagaaaga
     4861 aaacgtctat ttagacgagt tctttctttt ttgtttgttt caagctattt tttcctaaga
     4921 aaagaaaaac agcaaaaaat aattctaata atacaaaaaa taagataaag ctatgcatga
     4981 aaaattcttc tggaagtaca ttgatgattg gatcagtaac gggatcgaat aaccagtcat
     5041 cgttgttgaa aaacgtttca tgaaaaagga taaaaaagcg atcaaatcct atcatcatga
     5101 aaaaaccgaa aacaactggc agtaacatgc cgatttgaaa cggacgaatc aaccgccaaa
     5161 gccgatcatt cttttgcaaa tatttgataa acaaaatact cgggatcaaa gtgatgaaaa
     5221 acacagcata atccactaaa aacaaaattt tcacttcata aaagtgatgg gctccgctag
     5281 cagaaactgg gaaatctggc aagctgagga tggttttgaa gggattattg agataattca
     5341 ttaggtgatc aaaatttttc agtaacgtct cttgatctaa agaagtataa tccaaaattt
     5401 gcaaatgtcc gatatcaaat acgtatagtg gtcgaaagtt gatcgtcaca ccaactgcca
     5461 gactgatcag tgtcagaaat aggctgaaca atccagcata ttccatccac tgccatctcg
     5521 aatttttcat attagaagct ccattcatcc agtgattgtt tcacataggt agctgggata
     5581 ggcaacccag gtacatcttc ttcttttgta aaacctgata aaacgagcaa agtatctata
     5641 ttattgcgta tcccagcttg gatatctgtt tcatagttat ctccaaccat gattacttct
     5701 tctttttgca gccctaatac ttcaacggct ttatccataa tgatggcttc tggttttccg
     5761 atgtagatcg gcggcgtttg ggttgctgtc tctacaaaag agatgactga ccctgctcca
     5821 ggaagaaggc cgcgttcagt aggtatattc ttatctgggt tcgttccaat gaaagtagca
     5881 cctttttgaa tagcaagtgt tgctttaact actttttcat aggtcagata attatctaag
     5941 cctaccacta catagtcagg agcctcttct tcccatgtaa atccggcagc taaaatcaag
     6001 tcaatcaatc ctgcttctcc gataacatag acttttttcc cttttccatc tgctttcata
     6061 aaatcgattg ttgccaaagt agctgtgtag actgtctctg gagctacatg aatgtcaaac
     6121 tcatctgcta gacgattagc tactgtttct ggtgacttag tcgtgttatt ggtaacaaac
     6181 aagaaaggta attttctttt ttgcaattct tccacaaatc gtttaccggc cggtatgggt
     6241 tgtgtcccac gataaatcgt tccgtctaaa tcaattaaat atcctttata gtccattcat
     6301 ccactactct tccctttttc tgatcgtaaa tgctgttttt gttttttcta cttgtttagg
     6361 ttgttcttgt ttttttactt tttcagaggt ttttgctgac tctgtttttc gatttttaat
     6421 aaccggtttt ttgcgattag atgcgactgg tccttttttc tcatcgatat acgcacgatt
     6481 atggtttttt ttcttttttc ggcgctgagt tgtcttttct tttttaccgc cgattctctc
     6541 gatgacaaaa tacgcacaac caaaattgca atattcgtaa agatagtctt ccaaggaatc
     6601 gattcgctga tctggatgcg cccgtcgatt atccgcttgg aaaaatcctt ttaggcgtag
     6661 ttgttcataa ccccaatctc ctacgatata atcatatcgg gctagtacat cactgtaacg
     6721 ttctccaagc ttttctgcat taaatccttc acgataatcg gacacaagcc gataatgtct
     6781 ttcacctatc aaaaaattac tgtcatctaa cagtgtcact agctcgcctt tgactttttc
     6841 tgctttaggc tcctcaacga tttcttccaa agcagctgtc agttcttcgg tgactgttgt
     6901 ttcctgttca gctgatgatt ttttcttagc aatttctgtt ttatgctcaa cgttctgctg
     6961 ttcattttgt tttgcagaca tgcgttcacc acctatcttt tttattatac cttgttttta
     7021 tttgattggg tagtgagctt tcaagtaatc tcctaccaca cttcggataa attcagggaa
     7081 caaaaattca ttttttccag caatctcaat cgttggaaaa aatggaacaa acatcaaatg
     7141 atctacggta gtaaaagtat aatttttatt cagatcgatt ggcttgttct tccaaaagac
     7201 ttgatggtta atagaatcat atgtgattcc attatagacc atctgcccaa aaatcttacc
     7261 gcgaaatccc attcccttca taggatagtt acgtaaaaag ttacgatttt tttctatttc
     7321 taaaactaag cggatcagat catttccacc caatgtgaca tttaacaagt gcatcggatg
     7381 cggcaacgca gtgtgaagct gatcctgatt gacccgccct tttggaattt cagttaaaaa
     7441 cagaccactg tttaatattg ctgcttccgt ctttcctcgt tctttcaccg cctcaaaggc
     7501 tacttggata aacgaatgct cattgaagat atctagactc agagaaaatg gcaaatctgc
     7561 tacttctttt tcttttaata attcatgccc acgttctaga taactattta tttcttgttc
     7621 atcttctgta aaagctgtca ttgtttcggt agggatggct ttggctgaat gcttaaggat
     7681 ttttttctct tcatcgatgg ttaaatggac ttcaccgaca tactgcccgt actttccagc
     7741 ggctgctatt tggacatcat tgattacgtg accttctctg aataaatgat gggtgtgcga
     7801 tcctaaaata acatcaattg ctggtatttc ttttgcaatt tggaaatcat cctgaatccc
     7861 gagatgactc atcaaaacta aaacatccac ttgtgaacgt aaatcttcga ctaattctgg
     7921 caaaatatca taaggattcc gtatgtccca gccattcgga ttataagtaa gcggaaatgg
     7981 agcagtaaat gcaattagtc cgattttcgt ctggtgtttc gttgtaatga ttttatatgg
     8041 tttcgtccat gccggtggct ggagcgtatt tttatcgaat aagttatcca ggatgatatc
     8101 aaactcagca tgatcgtata aatgattcaa ctcttctttg gaatttccta cgccttcatt
     8161 gtttcctatc gtcgctgcat cataaccaac ttcattcatc agcaagatat tttcctgtcc
     8221 attcgttgct tctgacaatg gatgccaacg atccacaaaa tcacctagat ctactgcaat
     8281 cgttgtcgtt ttttctttct tttcgttttc tcgtttacgt tgatccaaaa accttctgat
     8341 ccttggccaa ttttctaaat gagaatgcag atcattcgta tgtaaaatca ctattttttc
     8401 catgtaccct ctcgcctctc tttatcttta tcataccata ggcagctttt tcttccattg
     8461 aaacaagctc tatttcagag tttttcctgc cttgaagcaa attgtataag tacaatattc
     8521 gataaatcag tctggctaaa aaatcaggaa cattcatttt tacagtacta taaaaataaa
     8581 aaaaacagac ccgaaagtct gttgtcgttt cattataatc agacacatgg cggaacctgc
     8641 ttagtgctgc ttccttccag acctgacacg cttcacaagc ccaccattgt cctagccttt
     8701 cggcaaagaa tagtatacct tatttttcat tcgttgacca gtcttttttt aatttctttt
     8761 ttcgctggcg gagctttcgg aaaaagtcag tcaaaatcat cccacattcg tcttctaaaa
     8821 tgccaccttc tacatatgct tggtggttaa accgctcgtc ctccaaaaga ttcatcaagg
     8881 taccggctgt tccgcctttt ggatcatacg cgccgaaata aacttctgct acacgagaca
     8941 aaatcatcgc gccgctgcac ataggacaag gctctaaggt aacaaaaagt gcagcatctt
     9001 ccaagcgcca gcttcccact ttttcacagg cttccttgat tgcaagcatt tctgcatgtg
     9061 tagtagcatc ttgcgtggtt tctctaaggt tatatcctct tccaatcact tttccatcca
     9121 atacaaccac tgctccaatc ggaacttcat gaagcatttc tgctttcttt gcttctgcca
     9181 atgcaaggcg catccatttt tctttttcta ctgcatcaag atttgtattt accaattacc
     9241 cttccctgcc tttgtttttt cttgttttac tttagcatat gataaaaagg ctgtaactaa
     9301 cttttttttc tatggtaaaa taaatacaag aggtgaacaa gatgaaaatg gataaattac
     9361 ttgctcttta cccacaagca cagaaaaaaa actctccagc atcagaagcg gatatccttt
     9421 cttttgcaat tgatgatgct tttatctgga tcaaacaaga ttcattatct caacaagaaa
     9481 ccagcctttt gaaagcgtta ttccctgtaa tcaacgatca aaaaaaacac ccatggtatc
     9541 actatctttt taaagatgct tcttgtgttc aagaaaaaag ctttcgtttg atccagcttc
     9601 acgtcgaatc aaaaggagaa ttcttaaaaa aagaatggca agatactatt ttggaattat
     9661 ttcgctattc tgctgatttc tttttttata cagacacaga tgcgctctta gtcgaacaaa
     9721 taaaccgtga ttatcttgat gctactgaaa tcaacggtat ttttctatct ttagatgctg
     9781 attttgatac gacaacgtct gtattcgttg gttctttcca ttcacctggc accgacctcg
     9841 tccctttgtt tgctgaagaa agaaaaattt ttttaacaga gcaaaacaat ctttatactc
     9901 acagccgtac tttttctatg caagatgtgg ctttacatta ctatacaaaa gatactgtaa
     9961 aagatagtaa gttgatcaaa agttacatag aactgatcaa acaaaatgaa atggaagtga
    10021 tcattcaaga attatggaat gaattaggca atgtcagctc tgctgcaaaa acactgtttc
    10081 ttcatcgtaa tactctaaaa tatcgaatcg aaaaatttca agaacagtct ggtttcaatc
    10141 taaaaaaagc caacgattta ctgttttgct atcttttatt gcttcatgaa cataattaaa
    10201 gatagattaa aggggttgtg acaataattt tgtcacaacc ccttatttcg aatgaatagt
    10261 gttcaaaagc tagtttctct tacatcattt tttcaacaaa atgcattagc cggtctttta
    10321 catcttcggt tgaatctttg attgaatcac cataaacaga gattttcttt tttcctgatt
    10381 tgatttttgc taacattccc atcaaagaat ccaagtcact atctgaaaga ccatctacga
    10441 tttctagtaa tttttcattt ccatcaaatt tgtcatagac gaattttttt actttcgtcc
    10501 gagtagtcat atgatggatc ttttccatta cttttcccga tacaacgact gctgtcgcta
    10561 cactggcagc ggctgctacg cttaatccga ttgttacttt tgttgatgtt ttcataagta
    10621 tcagctcctt tttatctatc tccatcatag catagacaaa aaaataaacg aactaatcca
    10681 ctcagtgaaa tctcaatcct ttagggaaaa agttctttac tgttcctttt acttgtttcc
    10741 caaatccgac aggtatctta tctaatacta gcaaaaccca tccttgattc ccatcacgtt
    10801 gaaatgtttc tcctgctgtg taagattgcc attccttttg agtgatcggc aagcaaggta
    10861 tattctctat cttttttgta gcaagcgcta atgcatagct aggttcaaat cgattctttt
    10921 tgaaatctcc taaatgcaaa cctgtacgta cgacttttaa accatcgaga gaaggggcta
    10981 actcaggaac ttcccaaaga tggtcgttga acactaaaag tcttccagta gcttcataat
    11041 gaaaatcatt tgaaaactcc gtccagagtt tttcctgctc ttttgtcatt tgcactttac
    11101 ttttttttcg tgtcttcttt tctttatgca tctgattttg tccatgaaaa gtcagctttg
    11161 caacaaaatg tccttcaccc tgatctttat gaggccatat acgtattgtt ttttccaaac
    11221 cagctacgct tccccattca gaacgtcctg aactaacgga ttgagtcaaa ggaatctcct
    11281 caatcgttac tggataattt tctacaagcc agctaatgat ctcttcattt tcttctggtg
    11341 caaacgtaca agtcgaataa atcagttgtc ctttattttt tagcattttt attgctgaag
    11401 acaaaatctc ttgctgacgt ttttgacagt atagcggaga ttcttctgtc cactctttta
    11461 ttgcatttgg atcttttcgg aacattcctt ctcctgaaca aggagcatca accacgatcc
    11521 gatcaaaaaa gcccgaaaaa tgagggacaa gttctgcggg tgcatgattt gtcactattg
    11581 cgttcgaaac tccccatcgt tctatatttt ctgataaaat cttcgcacgt ttcggaaaga
    11641 tctcattcgt cactaataac cctttcccct tcatttgagc agctaattgg gttgatttac
    11701 caccgggagc cgcacacaaa tccaaaactt tttcaccggg ttttgctgca gcagctgttc
    11761 caacgatcat tgcacttggt tcttggctat attcataccc agcttgatgg aggaaagact
    11821 ttccattgac agtgccaaga aatccctcat tgctgtaggg agcgggttgt aattcttcgc
    11881 tatggtaagt ttggaccatg tccaatcctg ccggttttag tggattccac cgaaatcctt
    11941 ttttcacgct tccttgttca agcgcagaaa aaaaatcgga tgcttcttcg cctaaaagaa
    12001 gacgatattt tttgataaat tgctgtggta acgttgtcgc ttcctccttc attccaatgt
    12061 ttcgttagac attttacaat cttttttacg aaaaataaag gtggctgatc tactttttca
    12121 tgttgctgcc taaggtgact gttcctttaa gatattttcc aagtattcat ccgtcacctc
    12181 gtttttatcc caaacagcgt tcatcatttc aagaaaatct tgagaagaat catctgagcg
    12241 caaacttccc aatgcattaa gccataccaa ttcaagcgac ttttcttctt tgatcttcgt
    12301 gtgacctttg acatatgaga aaaatggccg cttaaatagc gaatccatgt ctaaatcaga
    12361 ttttgcaatg atttcacgaa tactttcatg gatagaaaaa aaatctttca ataagtagac
    12421 aatgcttaaa acatcatcgg aactgcattc agctaagtag ttttcaaaat aaacagtgat
    12481 ttcttctaat atcttctctt ttaacccgct gattgatttg aaatgtgtat aaatcgggta
    12541 tgtagaacaa ccgcagaact ctgctaactc tcttgcagta attgacttca ttccatattc
    12601 ttccacgtat accatacttt tgaacagcaa atattcttta ctataatttg ttactctccc
    12661 catcattctt acctccgtct cttttcatct acccataaat aaataacata aataattcta
    12721 aaaatattat tgataattat caaaacatat ttagttatat ccattaaaaa tcaatttttc
    12781 cgccttaaaa acaagaatat cttgacaaaa taccctagga aataaacaat agaataaaca
    12841 aggtaacaaa aaaattaaat aacgttatat aaaaaagaag gcgacactct gtgagaataa
    12901 cacagactga aatgactttc cactcacagt ttttgtctaa ctatatacaa aaacagaata
    12961 aaaaggaggt atttatgcta attgaagcaa gaaaaaaaga gttacttgtt ctacaaatgg
    13021 tcattcaaaa aaataattgt tctttacaag aattatccaa tgacttacat attccaaaac
    13081 ggacaatcaa agaactgatc cgaaaaataa atgtatcact caagcaattt ttattgattg
    13141 atgaatttat ttattctaat cataaaggag agatccaaac caaagaaacc gatcaaacta
    13201 aaaagttagc tgttttttct aagttaaaat tatgctacct aaaagaatcc aatcgtttta
    13261 actatttgat gttactaatc aattatccac aaactgctgt accaaaaaaa tatttacttg
    13321 aacaacttta tatatcgccc tcctatctcg aaaaactgac aaaacagctc aatcattcct
    13381 taaaaaaatt ccatttacgg atcctatctg taaaaaattg ctgtactctt gaaggaaatg
    13441 agttatctat ccgtctctat ctttactttt ttctttcaga tacatttgga ggtaacgatt
    13501 ggccattttc ctcacttgaa ttaaatgcac taaaaatgaa cagtacagat gagcaaatag
    13561 aaaaaatttc aaaacaagaa aaaaatatct acttgctgtt aactttattc atattacgaa
    13621 acaaacaaca ggcatatttt ccaaaaactt cttctgaaat cactgaattg atggacttat
    13681 tgcagcatac acatgattat tcagaatact ttacttcttt ttcagtgagt cgcccttgtg
    13741 aagagacaga aacagagaga gcctacttta attatttttt ctattgtttt tttccaaatc
    13801 aaatctcttt tcgacaaaaa caggagattg gttttttatt ttccacaagc aaaaacctta
    13861 tttgtcgaca agtcggtcaa ttgatgactt acttaactca acagtttcct ctcaaccatt
    13921 tagaaaataa aataccaatt tatttttatt ttcttgtgtt ggcagttgtt tttttcgaac
    13981 tgttgggtga atccagcagt agtttttcta cactttgctt tccagaagcc acgtccaatc
    14041 attctagttc ttttatacag gaaaagaaat taagagaaaa aatcgataca attttttcaa
    14101 aaaatgggga aagaaaccaa atcagtcaat accttagtca attgatccaa cacttactac
    14161 aaacagaaac gaaagagcag ttactcatcc atttgcagat aaccaaacag tttacaggaa
    14221 attatcatct tcaaagccat ttgcagcagt tatttcgcaa agatgctgtt aaaattaccg
    14281 catattcaga acatgctgat ttgatcatta cagatcagca tgagaaaatt tcagatgaaa
    14341 cggagacttt ctatctggat acaacgcaca atacagtgtt atttggcgag ttaataaaag
    14401 cggttcatga actgtatatg aaaaaaggtt atgagaacaa aacaaagagg atgtgacaaa
    14461 attcttgtca catcctctta ttccaaataa atggtattca atcagctaac tctcggtatt
    14521 agctcagatc aaagcgctga tttcacaact tctttatttt aatctcttcg gttgccgccg
    14581 aacaataaga tcaagcgcaa cagctgcagg aatgtcgaaa gcgctgctgc aacataagtc
    14641 agtgctgctg caaataatac gtgtcttgcc atcggtactt cttcttccgt cagtagtccg
    14701 ccttcactca aaatttggat tgctcgccga gacgcgttaa attcgactgg taatgtcacc
    14761 aattggaaaa gtaatgctaa agaaaaagcg aaaatcccga tattgattaa cgtagagttc
    14821 cagctaagca atacacctac cataatcaag gggaacgaaa tcatcgaacc aaagttagct
    14881 gctggaacaa gtgctgcacg aatcttcaat gggacataac ccgaagcatc ttgtaccgca
    14941 tgtccgcatt catgagctgc tacacctatc gcagcaactg aagtagactg tgcagttgct
    15001 tgagacaaac tcaacatctt attacctgaa ttgtagttat ctgtgagatc tccggcaatt
    15061 tgttgaacac cgacattatt tatctgttga ctttgtaata tatattgtgc tgcttgtgta
    15121 ccagtcacat tgtttttgct tctcacttga tcgtattttc ggaaagtact attgacgtac
    15181 gctgacgcaa ttccggaaat aactaatcca agaatgacca aaagaaatgt cggatctaaa
    15241 aaaccataca ttccataacc atacattttc gtttcactcc ttttcgttta ctttatttta
    15301 tcattagtag taggaaaaga atgtgaaaag accttgaata ttctttaatt ctttttcaca
    15361 aattccgatt tcagtttcat cggtccaaat ccttctacct tgcaatcgat attatgatcg
    15421 ccttctacta aacggatgtt cttgactttt gttccttgtt taatggcacc tgacgcacct
    15481 tttactttca agtctttaat cactgtcacg ctatcgccct ctaacagacg gtttccattt
    15541 gcatctaata ccactaatcc gtcttctatg acagtttctt gttcttcttt gttccattcg
    15601 ttcccgcatt ctgggcaaat caacaagcct cgatcttcat atgtgtactc tgagccacat
    15661 tctgggcaat ttggtaatgt catcttcttt ctcctttaaa atctttagtg agcactattg
    15721 taacggaaaa agaagatctt gaaaagatac atttgtgatt tttactacaa aaggcacgtt
    15781 ttcgaacgaa gtatcattct gtttttctgc tcttatacga ttggcatata tcttggatct
    15841 ctttatagat ttcctctact tctgctaaat cttttgcatt cgcaccactt gctaatggat
    15901 ggcctcctcc atgatggcgt ttagccaatt cattgatgat cggcccctta gaacgtaaac
    15961 gtacgcggta ataccctgaa ggctgctgaa caaaaatccc ccaagccagc acttcgtcaa
    16021 tcactccagg aagtgaaacg atcgaagctg tctctgaatc atcgattcca tatttatcaa
    16081 gaatttcttg cggaaggatt attcttcctg caccattttc atccacctgg atattttgat
    16141 aaagataacc ggaaagttta gcgactttca tcggcatttg ttcaatctct ctgttcaaag
    16201 cacttgcatc aaatggataa tttctcaata tcgaagcaat ctctaatgta cgggacgtcg
    16261 tggagggata caaaaagcgc cctgtatctc cgacgattcc tgcataaagt aaccgtgcag
    16321 ccttaacgtt catctttaaa gattcaggaa acatcaaagc aaattctgca atcatctcac
    16381 tacagctact tgcttttgta tttacccaca caagatctcc ataagggtca tcattgggat
    16441 gatggtcgat tttgatcagt ttttctgcca actgatatct ttgatcactg attctgggtg
    16501 aattagctgt atcagtcacg atgactagcg ctccttggta gaagacatct tcaacttctt
    16561 gcatttctgc taaaaagcga agcccttcaa tcgtttcacc tacttgacgt atttcttttt
    16621 ctgggaaact ttcccgtaat agttcggcta atcctacttg tgatcctaat gcatcaggat
    16681 cagggcgcaa atgcctgtgg ataatgattt tatcgtattt ttttattgta tctactattt
    16741 cttgctgtac tgtcatttca ctcctgcttt ctaagaacgt tccattactt gacaaacaac
    16801 gattgctttg gaaacgatgg tgttttcaat aaacacttcg atatccagtt tagcggaacg
    16861 tctgccgatt tccaatacac gtggacgaat gtctaattcg ctttccaatt ggatcagccg
    16921 caaataatgt aggttcactt gttcaatcaa gatatttcgt ttttggttca tcaccattgt
    16981 tttttgtgcg acatcagaaa tgatttcgct aagtacgcca aaagaaatgg ttccaacgcc
    17041 attgaccatt tgtggtgcta ctacgaattt gaacttaggg ttttccaaac gatttccttc
    17101 acggtcagta tcaatcgtat ggatatttcc agatatctga tccgaaatcg tatctgcaat
    17161 ctgcggttgt cgctggacaa gctgcatcgc tttcattaca tcttgccggg taatcaagcc
    17221 ttccaatgtc aagtcatcgg aaacgaccgg catgacttct agcccatccc agatcatttg
    17281 atggctaaca gaggcaatac tcattgtttt ctttacactg attggttctt tcgtcatcac
    17341 ccgatcgatg atctggtttg gcgatttccc taaaacatct tttgccgtaa caatccccat
    17401 caaacgatga tggcggttga cgactggaaa acgcgaatgc tgcgtttctt ctgacaaacg
    17461 ctgataatca gaaatcgtat ctgtctgctg caaataatga gtcttttcag ctggcatata
    17521 gatatcactg acaagcatga tatctttttt gatcaattgg tcgcttaacg ctcggttgat
    17581 catggttgcg actgtaaatg tatcataaga ggtgcgtaag atcggcattt caagatcatc
    17641 agctagcttt gcaatctcag cagtcgtatt gaatcctcct gtgatcaata ctgcggcgcc
    17701 atcttccaat gctaattttt ggacttccgc ccggttgccg acgatcatta gtgatcctgg
    17761 cgtaatatag cgttccatgg catgtttagt catcgcgccg atgacgaatt tattcaagac
    17821 cttgtctaat cctgccgccc cgcctaaaac gtccccttca atgatcctga cgacctcgcc
    17881 aaatgtcaaa cgttcaatat gtttttttaa tttgcgttcg atacggatgg tccctactcg
    17941 ttgaattgtt gaaactagtc cgacattttc tgcatctttg attgcacggt acgctgttcc
    18001 ttcactgaca ttcaattctt ttgcgatgct tcttacagaa attcgattgc caacaggtaa
    18061 actttcaata tattctaaaa tcaaatcatg ttttgtcgcc attttctgcc tacacttcca
    18121 gcgtttccga gacgctcatt atttttcctt cactatcttc cagtaactct acaaaagatt
    18181 cgggatcttg ttcaatgaca gggaaagtat tgtaatggat tggaactact ttcttggcac
    18241 gaattgtttg cgcagccttt gctgcatctt ctggccccat cgtatagtta tcgccaatcg
    18301 gcaagaaagc gacatcaata tcgaattctt ctgcaagcaa tcctagatca ctgaaataag
    18361 cagtatcccc tgcatgataa atcgtttttc cttctgcttg aataataatt ccgctaggct
    18421 cgcccatata ctgaacgata ccgtctactt catagcttga actatgctgt gcatgtacga
    18481 attttaccac gccgaatgga aacgcatgtt ttccaccgat attcataccg aatgaatcta
    18541 ctcctctgct gttcgcataa tcagcaatct caacaatact gataattgtg gcttgatttt
    18601 cttttgcaat aggaatcata tctcctatgt ggtcactatg accatgagta atcagcaacc
    18661 aatctgtctt tacttcttct gcagttaagt ctgtcaatgg atttcctgta ataaacgggt
    18721 caatcatcac gcgttggcca ttttccattt caattgttaa acaggaatgt ccatgatacg
    18781 taattttcat attttacacc tcgcgttttc tctgtatctt ttttattaaa aacgatttca
    18841 tcacttgcac atcaatgaaa aaatatagct gctaaatata ttttcattgg attgatagta
    18901 cagtatgtac aaagcaattg taacagataa tacaggatgc accaagtacc aagcagatat
    18961 aatctcaagt ttgaggtctc tgctctgctt agcttctctt ctcgtccctt aactaattaa
    19021 atcagcgtaa ataggatgga cgatcttttc taaatcggct acttttatcc gaaggcttct
    19081 cccgatttca ccgcttgaca caattacttc ttctttttct tttaaagaac tgtctgctaa
    19141 aaaacaataa tcaggatgtg cgagttttat tccaataggg gtgtttgctc cgtggggata
    19201 tcctgtatgc attaatacaa aatccattcc aggaaaacca actttacgat ctttcgtcac
    19261 ttgtctcgtt tttttgtaat ctaagtgatc gttcaaagga atcaatgcga tgatcacccc
    19321 agttttgttt cctttcacta cgagagtttt acatatcaaa gctggatcaa tccctctttt
    19381 ttgtagttct tctgtgaaag attcttctac cacatgacta aaatcaagtg gttgatagct
    19441 gatcttttgt tcttctaaat aacgttcgac ttttgtttga ctcatcattg attcactccc
    19501 tttattctat cgtttattat aaagcgaggg atgctgtatt caaaaattat ttgtttttcg
    19561 caaaaaaaga gcaagacgag cactctatag agaggttcat cttactcttt ttgtttattt
    19621 tttatttcga cgttgagtag cttccataat gactggcaag atcactgggc ggcgttttgt
    19681 ttgttcaaat aagtaacggc ctaattgatc tcggatgtct tgctttaatt tgctccactc
    19741 aaaatcattg ctttctaaat gtttctcaac gattgtttca atcatattgc tgctttcttt
    19801 catcagatca cggctagctt ttacgtaaac gaatccccgt gaagtaattt gaggttttga
    19861 aatgattttc ttttctcgcc gactgatagt gacaaccgct acgaaaatcc cgtcttctga
    19921 caagattttt cgatcacgta aaacaatgtt tccgatatca cctatgccta atccatcaat
    19981 cattacattt tctgcacttg tagttcctgc aacactcata cgcttgttct tatattccag
    20041 cacgtctccg cgtccagtaa tatagatatt tttgtatggc atccctactg catgagccaa
    20101 atctgcatga gcagctaatt cacgatactc tccttgaact ggcacaaaat atgttggttt
    20161 catcaaattg atcattaatt gcaagtcatt aggattggca tggccagaaa cgcgcatatt
    20221 ctcagagatc aacttcactg ttccaccagc tcgataaatg atatcttccg ttttcgccac
    20281 gatggtttcc atcgcgatgc ttggcgtagt agtgatataa accaaatctc cttcttcaat
    20341 cttgacatta cggtgtgtac cgtttgccat tttttgcaga gacttgatgg gttcacccat
    20401 tcggccagtt tctaaaatga tcagttcttc tggatcatag tttttcatgt ctttcaacgt
    20461 aacaagcaga tcttcacttg gtaattgaag tttttctaaa cgcatcgctg tgcgaataat
    20521 tcgttcgaaa tcttgaccag tcaagacaac ttttcgttgt gctttttctg ctgcatccaa
    20581 tacttgttgc actcgttgca aattacttgc tacacaagcg acgatgatac gcccttccca
    20641 atatttgatc gtatcaaata cttcatctgc tatttgggct tcagaagcta caggctgagg
    20701 attttctgca tttgccgatt cacttagtaa ggctaagact ccttctttgc cgatttccgc
    20761 caatcgtgca taatctgttt gatacattgg gatagccgtt tggtcaaatt taaaatctcc
    20821 cgtataaacg atactacctt cttttgtttt cagattgatc cccactgaat ctggtatcgt
    20881 atgagtggta cggaaaaagc tcactactgt ttcaccaaag tctatttctg tatgctcatc
    20941 taccacatgg aaatccttaa atcctttggc tgcttcatta cgactgacat tcaattttgc
    21001 taactcgatc gtcaactctg tcccgaatac tggtacagaa atttttgaca acaagtaagg
    21061 aagtgccccg atcgcatctg catgtccatg tgttaaaaag acaccagcta cacgatcaat
    21121 gttttcttct aaatacgtaa aatcagggat tacgacgtcg atccccaaca actcattttc
    21181 aggatatttt agcccacaat ctaaaataaa aatatcctcg cccacttctg cgacatacat
    21241 gttttttcca ttttcacgaa cgccgcctaa tgggataatt ttaatggtac tcacaaactt
    21301 cacctcttct tatgacatcc aagtttaaag atgtcgattt tcttctttat ctaaatatat
    21361 gagccattcc aatgaagcat atgcaaaatc actatttctc aacttatgga gaatcagcag
    21421 gaaaattacc agcacatccg cgttctgaca gttggatggg cattttattt tggatatact
    21481 tcattaacaa aatggatctt ttgcgaaacg ctatagccag aatacttata taagtattca
    21541 gctgttcccc attattatac aacaaataaa ctaaatcgct agtatcagca attgttagaa
    21601 caactatgca cgtaaaaatc cctctgtagc atctaggatt tcttttgcta ttcctctttc
    21661 atttcttctt cgtcggtttg aaacatactt ttttcatttt accacatttt ttgcaataac
    21721 tatagtgact ttttatatat acagaacctc atgttgatgg tgtgcaaaca gcataagatt
    21781 taagctagct ttaagatagg ttgtctatta tcaaatgcat ctactaggag ggatgcaaaa
    21841 tatgaatttt atgaaacgtg catggaaaag tacaaaagta aaatggggac gttcattgtt
    21901 attgtttgcc gtgttcacag ccattcttat ttttgtgcta gctggcctca cgattcgaag
    21961 cgctgcagaa gaagcagcga atcaagcaca aaaagaagtt ggagcaacag tgactttaag
    22021 tgccaatcga gaagcttcat ttaaaaaaca ggaacaaact tcttcaagcg gttctaccac
    22081 tgaagaacgt ccagatccag gcagtttttc tcttacacca gtttccttaa cggacgcgga
    22141 aaaaatagct gaattagata atgtaaagag ttattccttt gaaagttccg cctcagctat
    22201 ggcaaaagat ggaataactg ccatcactag ttctgattca agtgaagaca gttcagaaac
    22261 tactgatgca ggcggtgaac ctgctggagg aatgggcggg aatccgcaaa tgactcaagc
    22321 agactttcaa atcagtggtg tgtcagcaac tgcacaaaat agtaattttt ctgatggaac
    22381 agcaaaaatc acggatggtg aaggaataga tgacagcgac aaaggcacaa acaatgtagt
    22441 cattgattct actctagcag aaacaaatga cctggcagtc ggagatactt tcacaatcac
    22501 gagtactgaa gatgaagata ccacttatga aatgacgatc aaaggaattt atgaatccag
    22561 cgaaacaagc ggcagtatgg gtatgaaatt caacttcatg aatccgtcga atacacttta
    22621 cacttcttac acttttgcaa atgaactaaa tgggacatct gacgataaca cgatagattc
    22681 tgctatttac actctatctg atccagataa aatggatgag tttctcaaag aagctgagaa
    22741 gctgatcgac acagatacat ttagcttaca atcaaatgat tccatgtatc agtcaatgtt
    22801 ggaaccttta aacaacgtgg caagtttttc taaaaatgtt gttttactag tggctgtagc
    22861 cggtattatc atacttactc tgatcattat gattaccatt cgggagcgtc ggcatgagtt
    22921 aggcgtcttg ctatctttag gagaatccag aagtaaaatc attctccaat tgtttaccga
    22981 agtggctatt tgtatgattc ttgcattagg agttgcttcg cttagcggaa acgtcgtcgc
    23041 gaatgccgtg ggacagcagc tacttgacca acagacagaa accacgacac aaaaccagca
    23101 agctcctggc ggtggacaaa tgccaggtaa cagacaagaa caaggcggtc aacgcgatgg
    23161 tcaacaagga accacgaata atccatttgc tgtttctgat caagtcagcg aattggaaat
    23221 caatgtcaaa cctgcacaat tgggactatt agccggagta gcatttggaa tcagtctgtt
    23281 ttctgtcttt ttagcttcta tagggatatt aagattaaac ccaagaaaaa tcctattaaa
    23341 ctaaaggagg aatttgatgt tacggacaga acaattggga ttttggtatc aagatccgca
    23401 agatgcgctt tataaagatg tagaactgaa tttcgaagct ggaaaaatgt acgctatttt
    23461 aggagcaagt ggttctggaa aaacgacttt tctttcgctt atttctggac tagatgcacc
    23521 aaaagaagga aaggtatact atcaagatcg ttcactgaac aaaatcgggt taagaagtta
    23581 tcgtaaaaat gatgtctcga ttattttcca agcttacaac ttgcttcctt atttatcggc
    23641 tctagacaac gtcatagcag caatggaaat cactaagacc aagcaagaga attatcgaca
    23701 agttgcttta gatcgactgg ctcgtgtagg aattgatgaa atattagcaa aaaaacaggt
    23761 gaccaaactt tcgggaggtc agcagcagcg agtcgctatc gttcgtgcta tctgctgtga
    23821 acatcaacta atcgtagcgg atgagcctac tggaaatcta gatgaaacaa cttcacaaga
    23881 tatcgtcaaa cttttccaag aaatcgccca tgaacaaaat cgctgtatta tcatcgtgac
    23941 tcatgagatt gaagtagcaa aaagctgtga tgaagtcttt gaactaaaaa ataaaaaatt
    24001 tcaaaaaatc gaagtttaaa aaacaggata atgatcaaat aaaaaatccg aaccatatct
    24061 gtctcgcaga tatggttcgg attttttatt tgcttgattc aattagtaat aagtggtttt
    24121 tatttttttt cgtcttttcg agaaaacttg tctttgactt cgtcgcctaa atttcgagct
    24181 ttttctttga tgtcagcacc tagtgattgt gctttccctt ctgtttcttt gctcttgtcg
    24241 tctgttgctt tgccgtatgc ttcttttcct tcaccgacta ctttatcttt catatcttta
    24301 gaacgtcctt ttaaatctgc cattgtgctt cctcctctta gtttgtttat tgatctacct
    24361 tcagggtaac atcaacaaca gatacagaca aacagaacgc tcgttttcta aaaaagatag
    24421 ttagagctgt tgattaaaaa cttttttcga aagtccccca tactttgact tctttttctt
    24481 ggaccattat ttctccttta gcgataactg tatcaatatc aagcgtttct ttatccaaga
    24541 tacacagatc tgcatcagca ccaatttcga tttttccttt tttatccaat ttcaatatac
    24601 gtgctggatt actggttata gctcgtaagg cgatttccaa agggatactt tctttttgca
    24661 cagcttcttt gatccctact agcaatgcct tggcacttcc tactcctaac cctaggaaat
    24721 gattgttttc atcaaaataa ggcaagcttc cttgtccatc tgaggtcatc gtgaaattat
    24781 ctaaagaaac atcttcctcg atcaatcgtt tcagtgcttt gctgaagcga acttcaccat
    24841 ctgtcttctc ccaaaaatca ggatcttcgc tagcagtgaa gtcaatcgtg ccaccacgtt
    24901 tggcaaatgc cacgcaagct tcaaataatt ctggtgtgcg atttgcatga gtaggcaaaa
    24961 attgtgtgat cggaatttct gtttcttcta cgattcgtgt caatagctct agctttcttt
    25021 ttcctccgcc taagtggaca ttgatgatcc cagcttttcc ggataacatg cctcctacac
    25081 gagcatctgc tactgcacga gcgaactctt caaaacttgg ctgagaagaa cggtgatcgg
    25141 atactgcgat ttctccgatt ccgataattt tatcaattgt caaaaagtct ttgatgatag
    25201 aatctgttac tgtttttacc ggcaatcggt acgaaccttc gtatacataa gtggagattc
    25261 cttctgcttc cagacctttc gctttgctga tcaacgcagt catatctcta ccttctccgt
    25321 ctgttcccaa acaaccgaca actgtcgtta caccagctgt agtcaattgg ctcaatgtga
    25381 cttctggcgt tcgattttga taaccgcctt ctcctcctcc acctaaaata tggaaatgac
    25441 agtcaatgaa acccggggtt agtacttttc cctcacctga aagttcttct acttccactc
    25501 cttcgtagcc gccttctagc tgttcttcta cagccaaaat cttcccaccg gcaatcagta
    25561 catccatttt tcctaagtaa tctggtgcaa acacttcaat ttgtcgaatg attttcatac
    25621 atttttcctc tttctttaag tataactgat gataggatct taaaaaataa tccaaacgat
    25681 aggatcttta ctcctttgat tttaccgtaa aatgacggtt cttggagtcc ttatctactg
    25741 tttggattac ttttttattt acaggtctcc agtactactg cagacctatt gcaatggcaa
    25801 tcatgatgaa aatagttcct aaaacaaaca ggaatccttg catcttgatt tggaatcttg
    25861 cccattttgc ccattcgatc cgtgcaacac ctagcacacc aatcaagctg gctgatacgg
    25921 gtgtaaaagc gtccataaaa cctgaaccaa gctgataagc aagaactgct acttgtctgg
    25981 atacacctac taaatctgcc agtggagcca tgattggcat agtcaaagct gcttgtcctg
    26041 aatttgatgt aacaaccaag ttgaacaaac tttggaagat gtacatcgcc caagcaccaa
    26101 tgacagctgg aacaccggtc aacgccgtcc cgatcccatg caaaatcgta ttcaaagctg
    26161 aaggaacaga tgcatcagat cctcccaaga caagaagaat ccctttggcc atacctacta
    26221 cgattgctgt accagctaaa tcagctgcac cagattggaa agaagaagcg atgtcattga
    26281 ctttcattcc atctaatttg aaaagaacag caatgattcc agcaactaat cccatcacaa
    26341 agaattgaga agcgatttct ggaatgtaat agcctttttg agtcacgccc caaacgatcc
    26401 agacaaggac aactaacatc tctaataaga tcaatttatg cccaagcatg aattttttat
    26461 tttcatcaga tgtctttttg atatgagaac ggaaataatc atctgatttg taagtcaacg
    26521 aactttctgg ttttttacgg attttttctg catatatcat catataacca gcggctaatg
    26581 cagtaacaac tacccacata atcaatcgga atgtcgcacc agacaacacg gggattccag
    26641 caatcccttg agccaccgct acgctaaacg ggctcatcca agaggtcgca tttccgactt
    26701 gagatgcgac ataagtcacg gttactgcta cgatcgagtc atatcctaac gcaatgacaa
    26761 atggaaccat caccattgag aatggaatta cctcttctgc catcccgaat gtagcgccac
    26821 cgaatgaaaa agcaaagaat aatagcggta aagctaaacg ctccagtccc ttagttttac
    26881 tgataaacgc atagatacct gcgtcgatcg ctccggtacg cataataata ccaaaagcac
    26941 ctccaacaac aaggatcaat gcagcgatcc ctacagcaga tccatactta tctccagata
    27001 ctagtccttc aaaaacaaaa tttaagaaac caaagccgcc aaaatcatct gttccccata
    27061 ttttggctgt tttatgcaat tttttagaag tatcatagat attttcgccg tactgatcgt
    27121 aaagcacatc atctgtcaag gagatttcat ctagtttttc ctgcgtaaga tttttttctc
    27181 cgtcagcaat gactttttcc aatccttttt ccggaacatc cagtttttca cgttctgctg
    27241 gatgatcttg cagttcttct aattgatcaa acacatacga cttatccagc tcgtaagcat
    27301 aacggaagga atcttgacgt aaaacagtac gagtacttgt ttcgccattt gcatctttgt
    27361 attcaatatc ttgcgtgctg aactttcctg ctggaacgac aaaagtcagt atccatgcaa
    27421 agatgactac accaaaaata atgacatacg tatggggtgt cgataattta gtgaagtcgc
    27481 gtttcggttt tcctgaagaa tttgttttct tcaaatttat ttcttccttt cttttttcag
    27541 taattttgat gaataaaaaa tggataatca aatgaattat acagtaaaaa tgacatttcc
    27601 acatgaataa tttattagaa aatcactttt ttctattttg ttttttttct cctatgtatg
    27661 attatttttt tctctttcca tttatattaa gtattttatt tctctgtttt tccttaaaat
    27721 tcttttttta tttttagatt agagaaaatc tcgtcctgtt tttttcattt tacaatcatt
    27781 gaaaaattga atttcattgc aaaaaaaaat aataaacact tataaatatc cattatctat
    27841 ccttcaattt ttgtgtattt tatttctatt agaaaaaggt atcctgttgg acaattttgt
    27901 tatatcaggt aaacttcatt gcaataatga taacaaatgt actataatta ctttgtaaag
    27961 agttttgggg aagactcttt catcaacgtg tattaagaga caagaaagaa tccatatgga
    28021 ttctttcttg tctctttttc cactactttt tatttttctg acactacata ttcttataac
    28081 tcatttctca taactgtgaa acaacttata aaaataacaa actttaaaca aaacaagctt
    28141 aaaatcaaag atgatccatc ttaaaataac taaaacaaaa aaagtagtcg ttgttaatcc
    28201 tcattaataa tcgttttctt tttttcaaac gctccatttt tatgtggaac attatttttt
    28261 taaggaactt tgtcaacatg tggataacta ttttccactt gtgtcctgga ctagctgttt
    28321 tgctgtaaaa tacaaaactt gctgcagcaa aaagatcgtt gcaagagagg ctgttccgca
    28381 gatcgctgga tctagatttg gcaaagtcaa gactgcatca tgtaaattgg cgtggttgtc
    28441 caaaaccaaa tcagcaaatt caaataatcg caaaccactg ctatgttgcg atttgatact
    28501 tcgtgacaaa tcaaatccag taacaatgat taatggatga ccattttctt tgatccactg
    28561 agctagttcg atgattgccg ggtttcttcc ttcattcgaa agaagaagaa aaatgtcttc
    28621 tgatttgaca gaaagctgat caataattgc ctgtcctgca ccttctagcg tttcatagac
    28681 acctccggct ggattttcaa tcaatatact tggtacaaga tccggggttt gatcccaaaa
    28741 ttcaaatgct acaccactta gtgtgcggct agcatatatc tgcaatctac caccttgatt
    28801 aatttgtttc gcgatccaag tgccagcttg aagcatcagc ggctcttcta tccttaattt
    28861 ctcttccaat tggtgataat agtcaaaata acataaactc atttatctct cccgcctagc
    28921 tatacttgac atgaatagaa acagctgcct aatctaagga agtacataaa aaaacagtag
    28981 ttagacagta acacatgtgg tctttgctgt ttcaaacaca aaaaaggcat tgaacgaata
    29041 cgcccaatac cttgacatag caaataaaac aacgtgcaga ccatggaaaa tatctacata
    29101 ggggtagaat tttcacccta gattaggtac aataaattag gtcgatgcac tgcattgact
    29161 atggcaaaat gatcggtcag ggtgtatgtg tgtgactggt cattccctga ttcttagcgc
    29221 caactaaggg tcagggagcc tttttttatt cagctgtttc tatctgaatt tattgtaagt
    29281 aatctcttat ccaagtgcaa gcaagaaaat acaaaaaaac attggtatga tttatatata
    29341 tataaataac ataaaaaaag gaatggctta tcccgataca acaagcattc ctttaaaaaa
    29401 gattctttta tataagtgaa aaaagctttt ttccaccaat taaataaatc tctcatctca
    29461 atagtttatc cattatttta tctttttttg cgtataccta ctaaatatta ccgtcttctt
    29521 ctcgttcttc tactttgttc gagagaatct gtactagaaa aagtagttgt atgtctacct
    29581 tttctgccta tccgagactt tcttttcata tatgggatat aaatgattag atacagtaca
    29641 gcaaaaaata aagcaaatac gcaagcttcc caactaccta acgccaattc aaccatcaag
    29701 gtagcaaccc caacggatgc tgcataccag ataaaaatca gaaacgtttc tttttttctg
    29761 accatgcgaa acatgataaa tagactaata agcaatagtg gcaacacaaa tatccaattg
    29821 cttccttcca tcagccactt gagtatatca agcagcgact gtgcaacagc gactaatttt
    29881 cccatagtga acacacacct ttttttataa ttaaaaaatt cgccttttta ttctactatg
    29941 aatcttctgg cttggctttc atttctctta tgtaatcatt ttcttttata caacttaaaa
    30001 aaaaattaaa ccattagcag aatattttct gaatctattc acgaaagtct ttttctatct
    30061 ttcgttttcc acgactcaac tgatctagag tcaaaaaact aaaacgacag ttgcgcaaat
    30121 gacgcacaag ctgccgcttt aataacaaat agcctttcat tctcagcagg ccacttattt
    30181 ccagttaact ttctgttctt agctttttac tcaactggat aatatatgca cttaatgaag
    30241 tcccaatttc cgaatgttga agtccatatt caatatttgt cttcatatat cctaacttat
    30301 cgcctacgtc gtatcttttt cctttaaact ctctcgcata gaccgcctct gtctggttaa
    30361 gagtctgaag tgcacccgtt agctgtatct cgtttcctgc tcctggttct tgagtttcta
    30421 atatctcaaa tattttagga gtcagtagat aacgtccgat aatggctaaa ttacttggtg
    30481 cttttcccat ttcaggtttt tctacaaacc cttttactct gcaacgaccc ttttcgctat
    30541 ctgttttagg atcaataatt ccgtatttag atgtttcatt ttctggtaca cgcatgacgg
    30601 caacagcgga agcttgtgtt tcttcataat ccatcatcaa ttgttgagtc aatgggatat
    30661 catctttcat caaatcatcc cccagcatga cgacaaacgg ttcatttcct ataaatgctt
    30721 ttgcttgaag cacggcatcc cccagtcctc ttggatgaga ttgacggatg aagtgaagat
    30781 tgacttgagt cgtttcttca actaaagcga gtaattctgt tttttccttt tcccgcaaat
    30841 tgttttccaa ttcgatattt gcatcaaagt gatcttcaat gggtcttttt tcttttcccg
    30901 ttacgatcaa gatgtcttcg attcccgaat ccaatgcttc ttccacaata aactggatcg
    30961 ttggtttatc cacgattgga agcatttctt ttgccatggc ttttgttgcc ggcaaaaaac
    31021 gtgttcctag cccagcggca ggaatgactg cttttttgac cttcacttgc tgttcctcct
    31081 aaacgacgat taactattga tcatctattt aacgaagaga aaattcattc tccatttttc
    31141 cgtcacgtaa catgatttct tttgctgctt ttttgatatc ttctccatta tacaaaacat
    31201 tatagattgt ttgagtaatt ggcatctcaa cacctagctg ttgagctagc tctactgctg
    31261 cttttgtcgt tgccacaccc tcaacgacca ttcccatgtt ttctagaact tcttccagct
    31321 tatgtccctg tcctaacaag ttaccggcac gccaattgcg agaatgaaca cttgtacaag
    31381 taacgatcaa gtcccccaca ccactcaaac cgataaatgt cagaggattg gcacccatcg
    31441 cgacaccaag acggctgatt tctgccaatc ctcgagtcat gattgctgct tttgcatcat
    31501 ctccgaatcc taatccatgg atagcgccgg caccaattgc aatgatattt ttcagtgctg
    31561 caccagtttc tacgccaatc acatcattat ttgtataaat cctgaaataa tcattcatga
    31621 acagtttttg tacataggct gctgcttttt gatcaatact tgcagctgta attgttgtga
    31681 tatcatgtac tgccacttcc tcagcatggc taggaccaga taatacaaca attgcctgtc
    31741 ttttttcttc tggaatttct tcagccaaaa cttctgagat tcgtttatgc gtatcttgtt
    31801 ctagtccttt acttgcatgt ataatgattg gcttagtatt cattttacca ataagttcct
    31861 gtgcgactga acgaatcgct tttgttggaa caacaaataa aatagcatct gcgttatcca
    31921 ctgcttctgc caattcttta tatccgataa tcgattctgg gatcgtcaaa tcaggtaaaa
    31981 aatgctgatt tgtatgatac ttattgattt catcaatctg ttcaggtaca tttccccaaa
    32041 tacggacatc atgcccgttt tctgccaatg tttgtgctaa agcagtgccc caagatccag
    32101 gaccaagaac tgcgattttt tgtttcatgg atattcctcc aaataaataa ttgataattt
    32161 ccattatagt atacatttct taaagttggg actaatttcc attgttttta agtgtttgtt
    32221 tacttctttt atcgttttta cttgaaataa tcaatgatat gttacaatag tctacatttt
    32281 atttttacac tcgttatgct ttgcttgttc ctaagaggaa gcagttttga caatgttact
    32341 accagcatta ctattaggag gttaggaaac ttctcctagt gagtattgat ttaaaataca
    32401 taagagacag attgaacatt tctaaatctg tcaggtcctg caacggacag attgtctctg
    32461 ttgacggttg acataggaac ttttgtttta gtcaacattc tggatacaaa acgctatgta
    32521 aactggcgca actcgttgta cttggacttt tactacggat ccatgcaaca actaaatagt
    32581 actattgcat aacaaaaaat ggttggcacc cacatgtccc attaaacaga ttataagttg
    32641 aactgtagat aatgcaaaaa atgtgtttta taacgtaatt gatgccaata ttttaaaaaa
    32701 ataaagggag cagttatcgc tgctctcttt attttttata ttctttttat ccagtctatc
    32761 ctaataatca aactgacgat agtagcggcg tatctctaat ggatggcagt tcaactgctc
    32821 cacatgagca tcgatgcgtt gtgtcactac atgcatcaat aagaaagaca aaacacgtcc
    32881 gcgatatttt tcactgatac cttctactgg atagtctttt gtgtctatca atgtataatt
    32941 gctgcaaatt tttggcaaaa gtttagccac acgttcagat aacactctct gttcatcttc
    33001 gcctaaaaat aatgtgactg gggttgtttc ttctacgatc tctaacgtcc cgtgaagaaa
    33061 ctcggcagca tggatagatt tcgatggaag ccagctttgt tcttcccagt aacacatggc
    33121 atatgaataa acagctcccc attgattccc tgctccaata aaataatgca tactatcacg
    33181 tcgatgtttt tctgcaaatg ataagccaaa tgcatctgct tttttctctg cttccactaa
    33241 ccctgttggt aaataacgtt cgagctgttc atagtattct gaataagctt cgaattctcc
    33301 attcaaatac atcaatcgat ctgctgccat aaaaaatttg atttgttctg ttccaggagc
    33361 tggataagtg accacaaaat cgcatagctg agacaactta ctgttcgctt tatcgataaa
    33421 tccaatcagt gtcgctccta ctttcttgat ttgttctact gctttcacta cttcttgagt
    33481 tgtaccggta acagaggaca aaataacgat agaatctttt gttaatcttt tgtttccagt
    33541 agtgtaatat tctgcagcat gctgtacaaa gacaggcaag ttgcttttcc cattcatata
    33601 agtgacagct tgcatcgagg aagcatacgt tccaccgatt cctagataat agacagcgtc
    33661 aaatttttcc gcataaagtt tatcgatgat ttcttctact tgcggacgta aagctagtgc
    33721 gccttttatt gctttgattt gttcttcttc attgaatttc agcatgattt ccacctctta
    33781 taatttactt ttcaagactg tatcaaagtc ttcaaaaatc tttttgttca agtcaatacc
    33841 tttagctact gcggttttat aagcgaatag ttgaaacgga acgacaagcg ctaatacaga
    33901 cagatattca tcacattcta ttgctaatcc aagtgttttc tcgtttcttg ctttttttgt
    33961 ggtaatggtg agagtctctc caacgtaccg actcatatat ctttgcaact tttgcgaacg
    34021 ttccttattt acactttccc cttcaataaa gaatagcaaa tgcgaagcat ctgcctccag
    34081 gtatgggccg tgcatataag cttctaactc aaatccttgt gacggaacgc ggattgtttc
    34141 agtcaatttc gtctctgctt ctttagctgt tccccagttt ggaccatatc caatggtgac
    34201 gaaacgctgt gctaaacgaa ataaactttg atatccatca aaaaattctt ccgttttttg
    34261 aataatcgct ggtaaatggt tgattatttt gcgcaactgt tgcatgtagt cttgttctat
    34321 ttttttgctg attttatttt tacttattcc aattcctatc cctaagagta gtaactgtaa
    34381 aacagtcgca gaatagcctt ttgtaacgaa gcctactgat tctaccccgg cacctaaatc
    34441 aataatttgt gcagcttcta aagcaagtgg actttgcacg tcatttgtga tagcaacaac
    34501 aggtaaccct tgtttttgta tcatttttac tgcttcaaca gtagaagcac ttttcccgct
    34561 ttgtgacaca gcaatcacag tatcgattga aggagaaagt tttccataat tgaaaaaata
    34621 aaaaggttct tgaatatcga cagtaagatc accataagat tccaatgctg gcttcgctgc
    34681 taaacaagcg ttataagatg aacccgttgc taagatcagt aaattcactg tttttttcat
    34741 atgttctctt gtcgaaaaat cattcttttt caagatcgta cttagtactt ccttttcttc
    34801 atagatataa tcttgcatcg taaacatttt ctctgctcct tttttaaaaa atccctatcc
    34861 acgaaccaaa aattccaaag aaagctagtc cgatcaagat cgttaatggt ttcacttctt
    34921 tcttcaatag ataaaacact atgccaaatg ctccaagaca taagatattt ggaacgatat
    34981 catcaaaaat actttgaaca gtcacagcat tttctcctga accgattttt aaaggaatat
    35041 tgatggtgat catcgtggca gtcattgctc caacgaccat cagtccaata atagacgcgc
    35101 ctaatgtcaa actttccatc ataccgtttg cctggatctt tttcaaaaaa cccgttccta
    35161 agcgatatcc ccaacctgtt gctagatagc gaaacagaat gtgcggaata ttgaaaatca
    35221 aaatgaacaa gatagggcct aaaatatttc cttgcatggc taaagaggta cccacacctg
    35281 tggcaatcaa tcgcaaagtt ccccaaaaga aagaatctcc taaccctgca agaggtccca
    35341 tcaaagatgt tttgatacta tcgatcgcag tcacatcaaa ttcaggatca tccttatttt
    35401 cttcctccat tgcagccgtg attcctaaaa tcagtgtaac gatatgtggg gtcgtgttaa
    35461 aaaactctag atgccgtttc aaagctgctg ccatttcttc tttcgactga tataactttt
    35521 tcaaaatcgg aatcattgca taaacataag ccatattcat ctgacgttca taattccaag
    35581 aaaactccat ttgaaaagaa cgccaaaata cgtgatttag ctcttttttc gttattttgc
    35641 tgtttttgat ctcagaattc ttcatcttct tctacctccc ctgcagttgt ttgaagtggt
    35701 agttgacgga cattcataat attgactacc acaactgcta aaatcgcacc aaaaatagct
    35761 actccggtca caggaatctc taagtaagaa gctatagcaa aacctaagaa aaaatatggt
    35821 gcaacttgtt tgttgatcag caaacgagca agcatcgcaa aaccaagagc tggaatcaac
    35881 cctgtagcta ctgacaaccc cttttgaacg aagtcaggaa tcatatttaa tagatttccg
    35941 atcgtattgc ttcccaccat ataagaaacc attaccacaa caccaagcat caaggaaaga
    36001 ccgataccgg caagcaagtg catatgctcg actcctttat aatttccttc ttctgcataa
    36061 ttgtctgctt tatggttcat aattggaatc aaaagcccta agtaaatatt tttcaatatc
    36121 aatgtcaacg tagcaatcgg caaacctagt aaaagcgcgg tttctgtacc ggctccagct
    36181 gtaatagcaa aagccgtccc taaaatccca ccggtcacaa catcaggtgg aatcgaagca
    36241 cctactgaga acgatccgat aaatgctaac tctaaagttg cgcccataat gatcccagtt
    36301 tttacatcac ctaacacgat tcctgtaaac agccccgtca caatcggacg agaaagcaac
    36361 gatgtcccta gtgcatattc tgattgtgcg acaaatgcaa caattcctaa taagactgct
    36421 tgtacaatca ttgaggttct tcctttctta caaaacttct cttacatcca cttttttatc
    36481 tgctggtact tgacggattt ctacttctat ttgtttgtca attaatcgtt tcaagcgttc
    36541 ctcctcttct ggtaaaatat ttaccgcttt tccgatgctg cgagtaccag gttttgcctt
    36601 gatccctcct aagttgatgg ttttgatttc tggatacgct tctgccagct tatatgcatc
    36661 ctcgatcgat tccactacga tgaataactt atatttatct gtcaccccgc ttttcaacgc
    36721 ggcaatcgag tcatcaattg atttgatcac tagtttgact ccttgtggct tggctaattt
    36781 gatcgttgtc tttcgtatct cattcgtagg tacatcatca ttagcaatca aaatacagtc
    36841 tgcgcctatt gtttgtgtcc atgaaaaagc tacttgtccg tgtaataacc gatggtcgac
    36901 tcttgtcaat acaatcattt ttcttcctcc taaaattcgt cttcttctat tttctgattg
    36961 agccgctcgt tacaaaactg gatcattttt tttgaatcag ttagcacctg ctggatcaaa
    37021 acagttgtct ctacttcagc gtccaaccga gatactagct caatcaatag tggcaaattc
    37081 aatccggcaa cgagatagac atgatcccga ttgatatatt gtaagaattc gttgttgaca
    37141 cttccgccaa aaagatccgt cagaacaatg atttctttat ctttgtacct cataaaaagc
    37201 tgccttactg tttccgctaa atcaaaattc tcatcagtat agcaatcgaa tacagtaata
    37261 gaatgatttt tcccatagat cagctctaat gaatctaata tccctgaagc aaattttcca
    37321 tgggaagcta agataatttc tctatccact ttttcatctc ctcttttcac ttacacatac
    37381 taaaaaagca agttgcatgc caaaattagt ggcaacaact tgcttatgtt caaaattctt
    37441 cttctatcga gagaaactct gtatcttcac tcaaaatatc atagatatag gcaatctcag
    37501 aattggggat catgacacta taatgctctt caatgacact aaacgcagat ttaatagcag
    37561 ataacccttc tttttgacac tgcttccatt tctctaatcc ttgataggtt tcgattggca
    37621 tttgtcggat caatcgttca atgagacagc tcacatggac atacaacgct aattttttgg
    37681 gattgctgat gcttcgattc aactgcacct ctaattctct cataaaatga tcgatttctc
    37741 ccatcacctt ctctgtatct agaatagtca cggaatccag tactttttcc aatgaaaaat
    37801 tacgaatgat gcgctgattg aatatttcct tctctgaagc attcatagta gtgtccaacc
    37861 attcagctag tacagacatc ttttcccccg agatgaggtc ttctaatgaa agatagtcga
    37921 tattggtgat atcaggatct gtggtgccaa tcattcctac gacttcgtat atggaaaata
    37981 atgggtcact gtttttctta tcttttaatt gctgatattc atatgggatg attttcaact
    38041 gacaagccgt aggtaagctt ttttctagca gttcacttaa gtggaccgcc gtaccgattc
    38101 cagtgaagca agtagtaatg agtgctttgg gtttgttttc ctctggatag agcagtcgcc
    38161 attctggctg gatctgtcga acagtctctt ctgctatctc ttctaatgat acattttttt
    38221 gcaggcattc ccctactgtg attgctaaag gtgtcgtcac attattcaaa atcaaaagcg
    38281 gtacggataa ctgtttttta aaaaactgat ggatttcttt cagagatccc atgtctacta
    38341 atatgatcaa tccatttgaa acatcgctgt tttcgcaata atcaaggatt tctgaagcaa
    38401 tctgctgtgg tgtgacatct agtggcatat caaatgattc aaatagatcc tcttgtaata
    38461 aacgatttac tacatttgcc atactgctag cagttgcata accgtgagca gcaatcatcg
    38521 cttttggcag tcgtttttct tttgaccatt tcgctttttt tagatagatc gtcagtaaaa
    38581 tccgatccat acttgtgtct tcaatatcta atttgatctt acttaattcc agaattcgtt
    38641 ggacatagtg ataactagat ggataagact gagaaacttg ttgttctaat tctttgatta
    38701 gttggataat atcatgttct tccggtaacc atttgatagt gcttcgctga tagagatagt
    38761 aactcaaggc atagacactg tttccatcga atttgatttg ataggcagtt tccatttgtc
    38821 gaaaggtctc tcggatagat tgtgtccaat aaaccagcag ctcgtgtttt tcttgtctac
    38881 tggtctcaaa cagcaaaaaa tcaaataatt gaatcacttc ttgctttaat tttccttcgc
    38941 aagaatatag cagacagtta tttttcttga aatcaattag gatttgctca aaacttttaa
    39001 cgattcgctg ctgttcgggc tgttgcttct ccattaattg ctctaaggtc tggtcttgcg
    39061 taatatagat tccttgctgt gctgtatttt tagtaatagg ctgcgcaagt agttcttttt
    39121 gcaaatgatg gatcgtgaca tggatttcag gctgttcacg ctgttcagca tatgcttttg
    39181 ctgctgaaac tttgacgata tttttcagct ctcctatgtt tccggataat ttctgacttg
    39241 ttaaaagtga caaagctggt ccactgactg acaaagggct ccccattttt ctttgttctt
    39301 cgagaaaaaa agagtaaatc agttctagcc gttcattacg actacgctga ttaagtgcag
    39361 gtagttcgat tcggataggt attcttcgaa tgaaagttgt taagaaatga ctagtaatct
    39421 cttcagtcgt agcaaaaaag agacgtgttt tgatccggcg tgacaaatta ggttctccca
    39481 tacgataaat cacaccttga tcaagatagg tgaacagttt ttcctgacct tctggtgtta
    39541 agcgatgtac ctcgtctaaa aacaagatcc caccatctgc tgcttcaaaa gccccttttt
    39601 tattttcttc tgcaccagtg tacgctccct taacatgtcc aaacaaattg ctagtcaaaa
    39661 gttcaggatt atctgcatat tgtgcacaat taaaagtgat gaatggtgca gaatcttcta
    39721 gcagatcatg aagcagacaa tactgataga ccaaattaac taaataactt ttacctgtgc
    39781 cactttcgcc tgtaatcaaa agtggtaatc cgccatctgg atagtaaaga gctgttttga
    39841 tttgttcgat actttctttc aaactggcgt cgtatccgat cataaaagag aataagtctt
    39901 ttggttgcgc gaaaaaaggc tgttcctctt tgagatcatc gatagaaaaa taaaaattcg
    39961 tgcgtaactt aaaaaattgt ttttcaaaag cttctttgtg gaaataaatc actggtcgag
    40021 aattgatttt gactagtagt tgctcatcat ttaactggtt caaataatga ctgactgtgt
    40081 ttctttttac cccaaaatga tcagctaacc tttgtgctgt aaagacctcg ttcatatgtt
    40141 ctaaatcgaa aaaggctgtc tggttctcta agtaacataa aatttccttc ttcaacaact
    40201 tattcacccc tcctccatca tagaaaacgg attcattttg tcaataaaat ctttaataaa
    40261 gaattgaaaa atatatctta ttatagacag cagcctactt atcccttata atttttattc
    40321 taaaaaacgt acagttcctt ccagttttta tactggaatt tcaacatatg aaagaataag
    40381 gaggctatga ctattcaatg aaatcggata aatataaaaa caggaaacat acttcctgga
    40441 aaacttttcg agaaatcatc ggatcttatc tcgctgtagt tgtatttttg cctttgcttt
    40501 atatggctat gacagaacaa actcgtttta ttggcgtaga tacgcaatat atagccgaaa
    40561 caggattttt attcatcttt atcttgattt ttgcgttcta taaatccttc catacaaaat
    40621 aagattcaca gatttcaact ttcctgtctg tttttagcta ttacaaatcc ttatatgtgg
    40681 tataacaaca atttattggc ataatgagga aaaacgagtt atgatgcttt cagagagtaa
    40741 agaggtactg ttgtcaccat cctttttatt gattacgtac accactctta gttttttccc
    40801 attgattacg aaaacaaggt agaaacattg atgttcctac cttgttttct ttttttattt
    40861 tcagatcaaa atctcaagta gcttttgact tgatgtcggg aggttgtctt cgttccatca
    40921 aacctgatag aatctgcgcc aaaccatagt tttctccact attatttatt cctctaagat
    40981 agtacccaca ataaacgaat aaatattttt ctcattttca tactccttct ttgaaaatca
    41041 attagatttc tctcaaccca cttttttaca aaaattacgt agcaaaaaag attgcaagaa
    41101 caaattaaaa aagaagtaaa tagagtttca tctataaaca tttacttgat atatttttta
    41161 tgcagaattc atttatagaa aaattaagta aaatagacgt tcctatgaat gaagagactg
    41221 gcatgttttc tcattttctt tt
//
LOCUS       DACGMI010000022        40842 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.022, whole genome shotgun sequence.
ACCESSION   DACGMI010000022 DACGMI010000000
VERSION     DACGMI010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.022"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..389
                     /locus_tag="IXT46_001290"
     CDS             <1..389
                     /locus_tag="IXT46_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-dependent endonuclease"
                     /protein_id="HAQ4947214.1"
                     /translation="QSEQYLERNLAMLKLANHVGKGWFAIELGEKIDFLIKIPKYILN
                     AIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSASLKTSDTADLNIAIISLLEYF
                     GKDEDVVYLINQIENYTKILYAEVSK"
     gene            386..2179
                     /locus_tag="IXT46_001291"
     CDS             386..2179
                     /locus_tag="IXT46_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAQ4947215.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            2379..2693
                     /locus_tag="IXT46_001292"
     CDS             2379..2693
                     /locus_tag="IXT46_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018705633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4947216.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            2714..3091
                     /locus_tag="IXT46_001293"
     CDS             2714..3091
                     /locus_tag="IXT46_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4947217.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            3101..3874
                     /locus_tag="IXT46_001294"
     CDS             3101..3874
                     /locus_tag="IXT46_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947218.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            3896..5299
                     /locus_tag="IXT46_001295"
     CDS             3896..5299
                     /locus_tag="IXT46_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAQ4947219.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            5481..6665
                     /locus_tag="IXT46_001296"
     CDS             5481..6665
                     /locus_tag="IXT46_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4947220.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            6662..6952
                     /locus_tag="IXT46_001297"
     CDS             6662..6952
                     /locus_tag="IXT46_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947221.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            6949..7170
                     /locus_tag="IXT46_001298"
     CDS             6949..7170
                     /locus_tag="IXT46_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947222.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            7212..7991
                     /locus_tag="IXT46_001299"
     CDS             7212..7991
                     /locus_tag="IXT46_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HAQ4947223.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            8058..8552
                     /locus_tag="IXT46_001300"
     CDS             8058..8552
                     /locus_tag="IXT46_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAQ4947224.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            8608..9246
                     /locus_tag="IXT46_001301"
     CDS             8608..9246
                     /locus_tag="IXT46_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947225.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            9318..9713
                     /locus_tag="IXT46_001302"
     CDS             9318..9713
                     /locus_tag="IXT46_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4947226.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            9697..12150
                     /locus_tag="IXT46_001303"
     CDS             9697..12150
                     /locus_tag="IXT46_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4947227.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            12147..14174
                     /locus_tag="IXT46_001304"
     CDS             12147..14174
                     /locus_tag="IXT46_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947228.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            14171..15193
                     /locus_tag="IXT46_001305"
     CDS             14171..15193
                     /locus_tag="IXT46_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAQ4947229.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            15210..16139
                     /locus_tag="IXT46_001306"
     CDS             15210..16139
                     /locus_tag="IXT46_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4947230.1"
                     /translation="MIIKIERKEKKERPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            16384..16500
                     /locus_tag="IXT46_001307"
     CDS             16384..16500
                     /locus_tag="IXT46_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAQ4947231.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            16516..17319
                     /locus_tag="IXT46_001308"
     CDS             16516..17319
                     /locus_tag="IXT46_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAQ4947232.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAY"
     gene            17494..17790
                     /locus_tag="IXT46_001309"
     CDS             17494..17790
                     /locus_tag="IXT46_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947233.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            17797..19749
                     /locus_tag="IXT46_001310"
     CDS             17797..19749
                     /locus_tag="IXT46_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAQ4947234.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(19821..20318)
                     /gene="dfrG"
                     /locus_tag="IXT46_001311"
     CDS             complement(19821..20318)
                     /gene="dfrG"
                     /locus_tag="IXT46_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAQ4947235.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            20680..21720
                     /locus_tag="IXT46_001312"
     CDS             20680..21720
                     /locus_tag="IXT46_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAQ4947236.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            21818..22006
                     /locus_tag="IXT46_001313"
     CDS             21818..22006
                     /locus_tag="IXT46_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4947237.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(22064..22417)
                     /locus_tag="IXT46_001314"
     CDS             complement(22064..22417)
                     /locus_tag="IXT46_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4947238.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            22948..23370
                     /locus_tag="IXT46_001315"
     CDS             22948..23370
                     /locus_tag="IXT46_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4947239.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            23367..23597
                     /locus_tag="IXT46_001316"
     CDS             23367..23597
                     /locus_tag="IXT46_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4947240.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            24095..24295
                     /locus_tag="IXT46_001317"
     CDS             24095..24295
                     /locus_tag="IXT46_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAQ4947241.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            24322..25515
                     /locus_tag="IXT46_001318"
     CDS             24322..25515
                     /locus_tag="IXT46_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4947242.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(25583..27148)
                     /gene="guaA"
                     /locus_tag="IXT46_001319"
     CDS             complement(25583..27148)
                     /gene="guaA"
                     /locus_tag="IXT46_001319"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAQ4947243.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(27207..28130)
                     /locus_tag="IXT46_001320"
     CDS             complement(27207..28130)
                     /locus_tag="IXT46_001320"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAQ4947244.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            28326..28931
                     /locus_tag="IXT46_001321"
     CDS             28326..28931
                     /locus_tag="IXT46_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4947245.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            29239..30255
                     /locus_tag="IXT46_001322"
     CDS             29239..30255
                     /locus_tag="IXT46_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4947246.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            30396..31697
                     /locus_tag="IXT46_001323"
     CDS             30396..31697
                     /locus_tag="IXT46_001323"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAQ4947247.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            31743..32405
                     /gene="deoC"
                     /locus_tag="IXT46_001324"
     CDS             31743..32405
                     /gene="deoC"
                     /locus_tag="IXT46_001324"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAQ4947248.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            32426..32824
                     /locus_tag="IXT46_001325"
     CDS             32426..32824
                     /locus_tag="IXT46_001325"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAQ4947249.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            32890..33972
                     /locus_tag="IXT46_001326"
     CDS             32890..33972
                     /locus_tag="IXT46_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4947250.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            34184..35746
                     /locus_tag="IXT46_001327"
     CDS             34184..35746
                     /locus_tag="IXT46_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947251.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            35739..36872
                     /locus_tag="IXT46_001328"
     CDS             35739..36872
                     /locus_tag="IXT46_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4947252.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            36872..37828
                     /locus_tag="IXT46_001329"
     CDS             36872..37828
                     /locus_tag="IXT46_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4947253.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            37927..39093
                     /gene="deoB"
                     /locus_tag="IXT46_001330"
     CDS             37927..39093
                     /gene="deoB"
                     /locus_tag="IXT46_001330"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAQ4947254.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            39117..39935
                     /locus_tag="IXT46_001331"
     CDS             39117..39935
                     /locus_tag="IXT46_001331"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAQ4947255.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            39952..40659
                     /gene="deoD"
                     /locus_tag="IXT46_001332"
     CDS             39952..40659
                     /gene="deoD"
                     /locus_tag="IXT46_001332"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAQ4947256.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT        13609 a         6983 c         8296 g        11954 t
ORIGIN      
        1 tacaaagtga acaatattta gaaagaaatt tagcgatgtt aaaactagcc aatcatgttg
       61 gtaaggggtg gtttgcaatt gagttaggtg aaaaaattga ctttttaatc aaaattccta
      121 agtatattct taatgctatt gcttttgcat gtcaggaaat agtagatctc tcaatttata
      181 aaaaaattct actccataca atcgacttgt acgaggaaac tacagaattg tcagctttat
      241 cagctagttt aaaaacaagt gatacagctg atttgaatat agcaataatt tctttattag
      301 agtactttgg taaagatgag gatgttgtgt atctaatcaa tcagatagaa aattacacaa
      361 aaatacttta tgctgaggtt tcaaaatgac aaatatcttc gaaaaaatcg taaatgattt
      421 aaatttagaa caaaaagatg ttgtggaaag tgaagataac ctttatgtaa atgcatgtcc
      481 tgggagtggg aaaacaaggg tacttacaag gaaaattgct taccaagcaa ttaaacacga
      541 tggatcacta aaaagaataa ttgctatcac atacactaat agagctgctg aagaaattaa
      601 ggaacgccta agtttactta gtatagatga tgatattaat atttgggtgg ggacaataca
      661 tcagttttgt cttgaattta ttatttatcc ttttaaaatg aatctctcaa gagtatcaaa
      721 aggatttaca attattgatg attatactca aagagcttac gtcagccaaa ttaataatat
      781 gctgaattta aatctcaaaa cgtatgaact gaacaaaatt gatttgtcac tttctcatga
      841 ttttaaaatt aatgaagttc agtatactca agtttctgaa atgtatcaca ctatgttgga
      901 aaaaaataaa gaaattgatt ttgatatgat tttactagta gcgtataaaa ttttaactgt
      961 aaacagtaac gttgcacgta atattgctag taatataagg gcgatttatg tggatgaatt
     1021 tcaagatact agagaattac aatacaatgt aatagctaaa ttacttcaaa acaaccctca
     1081 aattcagtca atgtttgttg gagatattga ccaagcaatt tatggatcat tagatggtat
     1141 agctaaatca gttgaagaac tagaaatgct aactagtcac acttttcaat caaagacgct
     1201 acatggctgt tacaggtcta atcagagatt agtagacttc tactctaatt ttcagagttg
     1261 tccttacgag attgaaagca gagggaataa taaaaacgac cgtggtttta taagttatga
     1321 ttgcaaagtt actaaggagg atttacccaa cataataaaa aatataataa aggaaaagat
     1381 tgaaagcggc attcatgaaa aagatatttg tgtacttgct cctcaacact atcctctgtt
     1441 ttcactgggt gagtatttaa agaaagaatt accgtattgc aattttgatg ctataaatat
     1501 atcaccaatt aaggtaaata atcatagttt atttttcaag ttagcaattt tgtactttac
     1561 tgaatcaggt gaaaaggttc gaagaagaaa gctaattgca aacgatattt taattatatt
     1621 aaaaaatgaa tttggaatag aagttaaaga ttattttatt gacttagatt tattacagct
     1681 aataaacagt gtgaaaagaa tgtatagtgg agacgacaac ggtgttgatt tatacaaatt
     1741 tgttaccaaa catatatttg ttaatcttaa tattgacgag aaaaattacc cgtctatttt
     1801 taagcactat ctatttttta ttaacgaagt agaagatcgg ataaaaaata attcattatc
     1861 tagtagtgta tctagtttta agaagatgtt taaatctcga gatggtatca cacttactac
     1921 agcacataaa gttaaaggaa atgagtatga tactgttatc gctattaatc ttctaaacgg
     1981 gaaaattcct cattggaatg aaatttttaa tgtttctgat aaaggaatta gttcagcgag
     2041 aaaactacta tacgtaattt gttcaagagc aaaaaataat ttatttcttt tctcagaggt
     2101 gggttatttt acgagtaaag gagacttgct ttatcccact caattattag ataaaataga
     2161 atttgattat aatatttaaa atacctaggt agtcgttgtt ttaaatatag taggaatcgg
     2221 acgctcagta cggagcgtct atttttttac ccaattttga aaggaagtga acttatgaaa
     2281 ataaaaaatc aagaatcaaa aggtcgctct ccccccttta aaaccatcac acaaataaga
     2341 ttcattcaaa cataaaaaca gaaaggatag gtaaaaatat ggaacttaaa tatgtcattc
     2401 ccaatatgga aaaaacattt ggacaattag aatatgctgg tgaagggaac attgaacaac
     2461 gtcgaataaa tggcagacca accattctct ctcgtagtta caatttatac tcaacgattc
     2521 aacgagcaga tgatattgtt gtcattcttc cctccgaagc tggcgagaaa cattttgaat
     2581 ccgacgaaaa agtcaaactc atcaacccac atattaccgc agaaggttat aaaattggca
     2641 atcgaggatt taccaattac attatgcacg cagacgatat ggtgaaagca taagaaagga
     2701 aaggtgaaaa aatatgagat tagcagaagg tattgtgatt gaaaaagacc agacatttgg
     2761 cacattgaaa ttttccgcct tgcgtcgtga ggttcgtatc cagaatgaag atggtacggt
     2821 ttccgaagaa attaaagaac gtacctatga cttaaaatca aaaggacaag gacgcatgat
     2881 acaagtcagt atccccgctt ctgttccttt gaaagaattt gactacaacg cagaagtgga
     2941 attaatcaat cctgtggcag ataccgtagc gacggctact tttcgagggg cagacgttga
     3001 ttggtacgtg aaagcagacg atcttgtatt aaaaggacag acaaaacctc atcagaaata
     3061 taaaaaagaa gcgtccgaaa gtgaaaaata ggtgttgctt atgacaaaca caccattgat
     3121 tttgaaagaa attccgaagg atgaagccat ttcttttatt cggcaatacc attattcaaa
     3181 gatactccct agattgtgta aatactttct agggattttt tcagaagaaa aattattagg
     3241 cgttgtggaa ttaggctggg gtacgcaacc cctacaaacc atacgcaaac tctttcccga
     3301 cagttccctt caaaccacag attatttaga aattggaaag atgtgttttc ttccagaaat
     3361 gaatcaaacc aattattttg gcagtcaagc tctttcagct ctaattaagt ggttgaaaga
     3421 acatacggac tgtcattttt tatatacact ggcagatgga attgagggaa aatgtggcta
     3481 tgtctatcaa gcgtccaact tcttttactg cgggtatttc aagacaagtg tctatcgtga
     3541 taagcagtca tgggaaaaga tacaccctcg aagtgctcgc cttttattag aggaaaatgc
     3601 tcgctttgaa caggtagaga aaaagcattg gctttcccag gcattttgcg aatacaaagg
     3661 gattgagaaa atcaatggac gcatgtttcg ctatctctat ccgttgacaa aagaagcgaa
     3721 aaaactgtta ggacacactc tctatcgacg tcattattat ccgaaagaaa aaaatttacg
     3781 ctttgaaaag cgaatcgctt atcagaaata tgaagccatt tctcaaccaa cttttgataa
     3841 acaggctcgt atctacaata cacaattatt ttgataggtg gaaaggagga tttttatgcc
     3901 attgcttcat gacagaggag agcgaatcaa agccaacgat aagcacttgg tctatcattt
     3961 tgtactaatt tcattgctgg tagtttttct agtcgtccta ctcccttttc attggagagc
     4021 gttacaatcg gtgaactggc aagcagttca gttagataca tttttctatc aacttcatac
     4081 gccatacttt tggagcagta ttctcactgc tctttttgta tgcggactta tcagctggct
     4141 ttattatcac tatcgtatag attctataaa acagttagag caccgtcaaa agttagctcg
     4201 tatgatttta gaaaatcatt ggtatgaagc cgaagaaact caatcagagg gattctttaa
     4261 agatttaccc agcaagaaaa ccaaacaacg aatccgccat tttcctaaaa tatattatcg
     4321 aatgaaagat ggactaatcc atattcatgt agaaatcacc ttagggaaat atcaagatca
     4381 gcttttgcac ctagaaaaca aactagaaac aggattgtat tgtgaattag tggaaaaaac
     4441 gttgaaagat tcttatgtag agtatgtcct actttatgat actattggca atcgaattgg
     4501 cattgaagac gtggtagctc aagatggacg tgtcaaattg atggaatcgg tctattggga
     4561 gttcgattct ctccctcaca tgttaattgc tgggggcact ggtagtggaa aatcctattt
     4621 tattctcaca ttgattgaat ctctcctgca tacaaatgca aagctttata ttcttgaccc
     4681 taaaaatgct gatttggcag acttaggggc ggtcatgaat aatgtctatt accgtaaaga
     4741 agatatgttg gcatgtatca atcaatttta cgaagatatg attgatcgca gtgaaaccat
     4801 gaaacaacac cctaactata aaacaggaga aaattatgct tatcttggtt tgtctgccaa
     4861 ttttcttatt tttgatgaat atgtggcaat gatggatatg ctaggtcgtg aaagtaccac
     4921 cgttattcat aaactcaaac aaattgtaat gttaggacga caagcaggct tctttttaat
     4981 tcttgcctgt caacgtccag acgcaaaata ttttagtgat gggattcggg acaactttaa
     5041 cttccgtgtg gctttgggtc gtatgtctga aatgggcttt ggtatgatgt tcggaagcga
     5101 tacacaaaaa caatttttct taaaacccat caagggaaga ggttacgtgg atacaggaaa
     5161 aagtgtgatt agtgagtttt atacacccct tgtaccaaaa aggtacgatt tcttaggaga
     5221 aataggaaaa gtcattcaaa aaaagcaatc tgagcctgta ccgcacgaag tgaaaggtac
     5281 aggttcagac ttgctttgat tggtgtggcg ttagccacgc caatccttta gccccctcta
     5341 tctaacaggg gggcacaaat acaactgaaa acaggcaatt ctcatcaacc aatgttgatg
     5401 gtacaaagga ttgcggaaaa tatgaaaggt gtaaactcaa gggtcatagt ttacatcttt
     5461 tttagattgg aggtttgcga atggaaaacg aaaaaatttg gattaaggaa ttgaaagaaa
     5521 agcgactggc ttatggcgtt tctcaaaata aactggcggt tgcttctcat attaccagac
     5581 cttacctatc ggatattgaa acaggcaagg cagtccctac tcaacaggtg aaagaagatt
     5641 tactgaacgc tttggaacgc ttcaatcccg ataacccatt ggagatgtta ttcgactatg
     5701 tacggattcg attccctacc aatgatgtgg ctcaaattat cggtgaggtt ttacgtttga
     5761 atatggatta tatgctacac gaagactttg gctattattc ttatcccgaa cactatcgtt
     5821 tcggtgatat tgttgtccta gtctctcatg atgtaagtaa aggtgtttta ttagaactga
     5881 aaggaaaagg ctgtcggcaa tttgaaaact ttctattggc tcaacatcgg agctggtatg
     5941 atttctttca agattgcatg gaacataaag gtattttcaa acgcttggat ttagctatca
     6001 acgataaaac agggattttg aatattccag atttggcaaa gaaatgtaaa caggaagaat
     6061 gcatttccgt ctttcgaagc tttaaaaatt atcgcagtgg tgaattggtt caccgtgatg
     6121 aaaaaccata catgggaaac acactttata ttggctcatt aaaaagtgaa gtctatttct
     6181 gtatatatga gaaagattat gagcaatacg tgaaaaatga tgttccctta gaagacgcag
     6241 aagtaaagaa tcggtttgaa attcggttaa aaaatgaccg agccacccaa gccatgaaag
     6301 atttattggc acatcaacag gcggaaaaaa cagcctttga aattatcaat cgctatatcc
     6361 gctttgcaga taaagacgac actaaacgtc ggagtgattg gaaaactaat gaacgttggg
     6421 aatggtttat cggtaaaaat cgtggagcat tacgcctaac cacacagcca gagccttatt
     6481 cttttgaacg aacattgaac tggttacatc atcaagtcgc ccctacatta aaaatcgcaa
     6541 gcattttaga tgttctcaac ggtacaacca ttatctccac catgattcag gaagccaaac
     6601 tgacagaaaa acatgagaaa ttaattgaac aacaacatct agccatggag gatttgatta
     6661 catgagcctt ttaacaaaag aattaaagaa gttagggttt cagtgtggca ttgagtttca
     6721 agcgtatata caaaatacag ggaaatatac gtctctcatt attgagggaa aacggcaagc
     6781 tggtgatacc atctatacct atgattttta caaggtgaga ttttataata attataccaa
     6841 tcgagtaacc gtctatggag agcatttaac cccttttcaa ttattaaggc gtgtaaaaag
     6901 ctatatctat tatcgagaaa aatatcttaa ggaaaggagg acaatcacat gaattttggg
     6961 cagaatttgt acaactggtt cttggataat gcacagtcat tggtattgtt agcgattgtt
     7021 gtcattggac tgtttttagg ttttaaacga gaattttcaa aactcattgg cttcttgatt
     7081 attgctctaa tcgccgtcgg acttgtgttc aatgcagctg gcgtgaaaga tgtgttatta
     7141 aacttattta accgaatcat tggtgcttaa cagatatttt tcatgataaa ataggaagta
     7201 tatattttgt tatgaaagga tttatgaata tgtttacaaa tgatcaattt aaatctcttt
     7261 taattaaaac attagaaaga aagagctctt caaattatta tgaaggaggt aacgagattg
     7321 tttctaaaat gaaaatatca gaggtaactt tagatgagac tgacgatttt acttattata
     7381 aaggatataa aaagggctgg aatacgcttt gcacatatct taaaataaga gttccttttg
     7441 atgatttaga cttttttgaa agtcataaag atttgattac ccagacagca agctccatat
     7501 atgataaaca aggtgataat gtattagtgg atactatttt agtaccactt ccagagaatt
     7561 acgaagtaat taactttagt cagttgaaaa ttagtgatgt ggtttcacaa gctattgaag
     7621 acgctgagtc ttttatgagt aatggtgaat atcaacgtgc ctttgacaga gttcacactg
     7681 cttttcatgg atatttaatt gaaatactaa aaaaatatga aattacagtt cctagagacg
     7741 aaaatctatc taaattatat agtaggatac aacaattaat tgaaaaagaa attcaaccta
     7801 ctgaacttgc tgatatagtg aagacaacga taaggtcatc aaatggaatg attagctctc
     7861 ttaatgaagc aagaaatagg cattcacttg cacaccctaa tacaaatatt attggaaaga
     7921 gagaagcaaa actaataata ggtatttcaa gtacagttac agattatatt agcggatacc
     7981 ttgataagta gcgtcattaa ctgattgcta ctttttttat gactattttt ataaaaagga
     8041 tgtgataaga attggaaatg aaagtctatg tggcaaattt aggacggtat aatgaaggtg
     8101 aattagtcgg agcatggttt actccaccaa ttgatgagga agaaatggca gaaagaatcg
     8161 gtttaaatga ggactacgaa gaatatgcaa tacatgattt tgagcttcct tttgatgtgg
     8221 acgaatacac gccgattagt gaaatcaacc gtctatgtga agccattcaa gaaatcgaag
     8281 gtacacctat ttataatgaa ctcaaagaaa ttcaaggcat gtggtttagt agcttggaag
     8341 aattactgga aaacaaagag gatattcatt gttatagtga ttgtgattcg atggaagatg
     8401 tcgcccgtta ttacgtggaa gaaacaggac agcttggtga agtcccttcc aatttacaaa
     8461 attatattga ctaccaatct ttgggacgtg atatggaaat agagggtaat tacctagtta
     8521 cctctcatgg ggtatttgaa tattgtcagt aagtttaaca atccgtgtta taattaaatt
     8581 aataaatagc acggagaggt ataaattatg gtaaatgtat ttgaaaatct taaactatta
     8641 aaactagaca tgaaagataa aggctgggtg atagattcct tttactttcg ttacaaacag
     8701 caaaattata ttgtacttgt taagctattt gaaaaagagg aaaaagttcc agaatatgct
     8761 ctgttaaaac tagaattttt aaaggaaaac gatttttcag atatgctagc tgtctatgct
     8821 aattcggtaa aattatatac agacacgaaa acaataagag aatattttgg tatcgaatac
     8881 agtagtaact tgggagatgt tttatttcaa tttagccaaa ctcttgctcg atttattccg
     8941 acagaagtta gtgagaagaa aaatgaagac caaaaagaag ccatgtgttt ctcattaagt
     9001 caaagtgatt cagaagatcc cagaaaaaaa tattgttttt cagttagaag aaatccttta
     9061 aagggaaatg gtgagctggg aaaacgaagt ccttttaatg acaataaaac gagattgtat
     9121 agacccagct tatatgaacg attagggtca gataccaatt taagtttcag atattcaatg
     9181 aatccagatg atgaagaaac tgatgaaggt attattgcaa aatggacaaa aaataaaatt
     9241 gaatagttaa agcattgaaa gagcaatcac ctattttgat tgttcttttt ctatttttac
     9301 ggaaaggacg tgaagacatg aaaaaaataa gaagttacac cagtatttgg tcagtagaaa
     9361 aagtgattta tgcgattaat gatttacaac tccctttccc aattaccttt acgcaaatga
     9421 catggtttat cgtttctttg tttgtcgtca tactctttgg cagtttacca ccactttctc
     9481 tgattgacgg agcactactc aaatacttag ggattcccat tgttctcact gggttcatgt
     9541 gccaaaagac ctttgacgga aagaaaccct atggatttct aaagtctatc attacctatg
     9601 ctctacgccc taaagtaacc tacgctggca aacaaatacg attaaaaaaa gaaacaatga
     9661 atgaatcgat tacgattgta aggagtgaac aactagatgg catatccgat taaatatatg
     9721 gaagataatc tcgtatttaa tcatgatggc gaagtattcg cttattatga attaattccc
     9781 tataattaca gttttttaag ttccgatgaa aaaattcaag ttcatgataa tttctgtcaa
     9841 ttgattgccc aaaatcgtga tggcaagatt catgctctgc aactagcaac cgaatcaagt
     9901 attcgagcca cacaggaaca atcgaaaaaa gaaatcactg gacgattaaa agagatagct
     9961 tacgaaaaaa tagatgaaca gaccgaagcg ttaatttcta tgattggtga caatcaagta
    10021 gactatcgct tttttattgg ttttaaactc tacctcaatg aacaggaagt atccgtaaaa
    10081 aatgttggga aagaaattca aaaagcattt gcggaattct ttcatggtgt gaatcacaaa
    10141 ttaatgggcg attttgtttc tatgcctatg gcggaaatcg aacgcttttc taagatggaa
    10201 cagttgttag aaagtaaatt atccagacgc tttcagattc gtaaattgga gaaagatgat
    10261 tttggttata ttattgaaca tctttacggg caaacaggtg tcccttttga tgactacgac
    10321 taccatttac cgaaacgata cgaagataaa aaagtgttgg taaagaaata cgatattctc
    10381 aaacccactc gctgtttaat cgaagaaaat caacgctatt tacggattga acaggaagat
    10441 accactactt atgtggcgta ttttacaatt aatagtattg ttggtgaatt ggatttccct
    10501 aatagtgaaa ttttttatta ccagcaacag cagtttactt tccccgttga taccagtatg
    10561 aatgttgaaa ttgtcgccaa taaaaaagcc ttatctaccg ttcgcaataa aaagaaagaa
    10621 ctgaaagatt tagatagcca cgcatgggaa agcgacaacg aaaccagtac taatgtggtg
    10681 gacgctttag aatctgtcga tgaattagaa agtaatttag accaaaccaa agaatctatg
    10741 tacaaactaa gctatgtggt acgggtatca gcaaagaatt tggacgagct gaaacaacgt
    10801 tgtgatgaag taaaagattt ttatgatgat ctgtctatca aattagtacg accttttggc
    10861 gatatgctag gcttgcataa tgaatttatt ccctcaagca agcgatatat caatgactat
    10921 attcaatatg tcacgtcgga ttttttggct ggtcttggtt tcggtgctac acaaatgatt
    10981 ggtgaaaatt ctggtattta cgtcggttac aatctcgata caggcagaaa tatttatctc
    11041 caacctagcc ttgcaagtca aggaattaaa ggctctgtaa caaatgcatt agcgtccgct
    11101 tttattggtt cattaggtgg cggaaaatca ttctctaaca atatgctggt ctattattca
    11161 gtactctttg gcggacaggc aaccattgtt gacccaaaag ctgaacgtgg tgaatggaaa
    11221 gaaaccttac ctgatattgc ccatgaaatc aatattgtta atctcacgag tgagaacgac
    11281 aataaagggt tacttgaccc ttatgtgatt ttaaaactcc cgaaagattc agaaagcctt
    11341 gccattgata ttctcacgtt cttaacaggt atttccagcc gagatagcga gaagtttcct
    11401 gtcctgcgta aagctattcg gagtgtaact caaagcaaac aacgagggtt gttattggtg
    11461 attgatgaat tgcgaaaaga agatacgccc atcagcaata gtattgctga ccatatcgaa
    11521 agctttgtcg attatgattt tgcccatctg ttattcagtg atggcagtgt cacccaatcc
    11581 attagcttgg aaaaacaact caatattatt caagtggcag atttggtctt acccgattcc
    11641 aatagctctt ttgaagaata cactaccatg gaattattaa gtgtggcaat gctgattgtc
    11701 attagtacct ttgctttaga ctttatccac tctgaccgtt ccatttttaa aattgttgac
    11761 cttgatgagg cttggagttt tttacaagtg gcacaaggaa aagctctatc tatgcgattg
    11821 gttcgagcag gacgtgccat gaatgcaggg gtctatttcg ttactcaaaa cgcggacgat
    11881 ttactagatg aaaagatgaa gaataatatt ggcttgaaat ttgcctttcg ttccactgac
    11941 ctagtggaaa tcaaaaagac cttagaattt tttggtgtgg acaaggaaga tgaaaacaat
    12001 cagaaacgct tacgtgaatt agaaaatgga caatgtttag tttcagacat ctatggtcgt
    12061 gtaggggtta tgcagtttca cccgattttt gaagagttgc ttcatgcctt tgataccaga
    12121 ccgcctgtgc gaaatgaggt ggaagaatga cacaaaaaca aaagaaattt cttcactata
    12181 gttggataac gctcctttgt gtgggcgtta ttttactttt attaggcacg ctgggcaatg
    12241 cagtacaagc gacaggctta gttgatgaaa ccattgatac aagcaatgaa tactccaagt
    12301 atggtttgaa tcaatatcag cttgattatt atgtggacaa tagctggggc tggcttccat
    12361 ggaattggag tgatggcata ggacaatcgg tgatgtatgg attgtatgcc attactaatt
    12421 ttatttggac aatttctctt tatctatcga acgccacagg ttatttggtg aaagaagcct
    12481 atgccttaga tttcattagt caaacatccc aagcaattgg cgaaaacatg cagacgattg
    12541 caggcattac accgaatggc ttttccagtt cagggtttta tgtcggtttc ctccttcttt
    12601 ttattctcat tgttggaatc tatgttgcct atacaggatt ggttaagcga gaaacgacga
    12661 aagtgatacg agctgtttta aactttgtcg tggtgtttat tctatcggct tcctttattg
    12721 cgtatgcacc cgattatatt gcgaaaatca atgatttttc caaagatgtc agtaccgcca
    12781 gtctgaatat tgggacaaaa attgttcttc ctaacacgga tagtcaaggg aaagacagtg
    12841 tggacatgat acgtgacagc ttattctctg ttcaagtaaa gcaaccatgg ctattgcttc
    12901 aatatggctc cactgatgta gaagcgttag gggaagaacg tgtggaaagt ttattgtcta
    12961 ccagtccaga tacaaacaat ggtgaagata gagaaaatgt agtgattgaa gaaattgaag
    13021 atcatgacaa tacctattta accctaccga agacgatttc cagattagga acagtcttct
    13081 ttttgtttgt attcaatatt ggtatctcga tttttgtttt ccttctaaca ggaatcatga
    13141 ttttttcgca agtgctattt attattttcg ctatgttttt gccaatcagt ttcctattaa
    13201 gtatgttgcc gagttttgat ggcatgggca ggcatgccat taccaagtta tttaatgtga
    13261 ttatgacaag ggctggtatt accttgatta ttaccgttgc ctttagtatt tccactatgc
    13321 tttattcgct gtcagcaagt tctccctttt tcatgattat gtttttacaa attgtgacct
    13381 ttgcagggat ttattttaaa ctgggcgatt taatgagcct attcacttta caaagcaacg
    13441 actctcaaaa catgggcaga caagtgtttc gcagacctcg tcaaatgatg aatcgacaaa
    13501 ccagaagatt tcaacgcagt atgagtaaga tttttcgtgg aaaagcaggg tcaacgaagc
    13561 aaaagacaat gacaacaaag cagaatcaaa ccaataaagc taaccatact cgtcaaaatg
    13621 aacggactac accaaagaaa gaaacagcac tttccaatgt gaaaaagcaa caaggcggta
    13681 tcgggcaacg attaggtgaa aagacagccc atgtattgga cacgaaaaat cgtctagtca
    13741 ataaaagaaa gcaggcaaaa caacagatac aggcgacacc aacccatgtc aaatatgccc
    13801 ttcatcaagg aaaagagaat gtcactcata atgtaacaga ctttaaacaa tctatggcag
    13861 ataccaaagc tcaacgcaaa caacagcgta tgaaccagca ggagcaaaaa cgaaagaaca
    13921 ttgctcaaaa gcgtttggag ctggataaag caaaagaaaa aagacgaaaa gaaaacccat
    13981 catctcctgt tcagaataac cagcagcatg ttcgcaagcg tcagcaaacc gtcacgcctg
    14041 ttttgtcaca aaacactaaa cgtgaaaatc atcagcgacc attgaaaaaa gagcaaaaac
    14101 aaaagacacc accgaagcaa ttcaatcaga ggaagctaaa taaaagaacg gataagcgag
    14161 gacaacaaac atgaagctaa aaataacagt gatttgtagt gtggtcttct ctctcttctt
    14221 ttttctctta ttattcctag tcattttctt tgcagatgat acggacagtg gcgaaaacaa
    14281 caaggattct tctattccac aaggcggtgt gaccgtttca ccagaagtgt tggcacaccg
    14341 tccgttgatt gaaaaatatg gtaaggaata tgggattgaa gactatgttt cttatatctt
    14401 agccattatg caagtggaat cgggcggtac agcagaagat gttatgcaaa gttccgaatc
    14461 tttgggttta ccgcccaaca gtttgagtac cgaagagtcc atcaaacaag gggttaaata
    14521 tttcagtgaa ttattaacca gtgcagaaca acaaggagtg gatatagatt ctgttatcca
    14581 atcttataat tatggcggtg gctttttaaa ttatgtgagg agtcatggga aaaaatatac
    14641 ctatgaatta gccgaacagt tttctaaaga gaagtcgggt ggtcaaaaag cagactatcc
    14701 caatcctata gccatacctg tgaatggtgg ttggcgatat aactatggaa atcagtttta
    14761 tgttcagttg gtttcacaat acctaaccga cacttcccca acagaatttg atgatgaaac
    14821 cgtgcaagtc attatggacg aagccttgaa atacgaaggg tttccctatg tctttggagg
    14881 ggcgtcgcct accacctctt ttgattgtag tggcttaata caatgggtgt atgacaaagc
    14941 tggcatttct ctccctcgtg tcgcccaaga tcagtatgac gctacgcaag aaatctctat
    15001 ggaagaagcc caagcaggcg accttatctt ctttcattca acctataatg caggcacata
    15061 tgtgactcat gtggcgatat atttagaggg aaatcgcttt tatcatgcag gcgacccaat
    15121 cggttatggc gacttaagca gtcgttattg gcaagaccat ctgattgggg ctagacgtgt
    15181 tattcataac taagaaagga atgaatcaaa tgattataaa aatcgagcga aaagaaaaga
    15241 aggagagacc aaagaaatct aaaaaaccga gcaagcaaag aaaagttccg atgattaaag
    15301 ttggcacgca taagaaatta acctttgttt tatgggtttt attgattggt agtgtcggat
    15361 ttggaatcta taaaaatttt actgccattg acactcatac tgtccgtgaa acagaaatca
    15421 ttaaacagca gattgtcgat accaaccaag tagaaagttt tgtgaaatcc tttgcgaaag
    15481 actacttttc gtggcaacaa tcccaagaag ccattgataa acgaaatgaa aaattgaccc
    15541 attatttgac ggaagaattg caggtattaa atgaagaaat gattcgtaag gatattccta
    15601 ctagttctag tgtgaacgat atacaggtgt ggcaggtttc tcaagtgaat gagaacacct
    15661 ttgaggtact gttttctgtt gaacaagtta ttaccgaaga caaagacaag gaaactatat
    15721 cgtctagctt tcatgtggtt gtccatatag atgaatcaga taatatggtt attatcaaaa
    15781 atccgacaat gagtaagaaa cctcaaaaat cggactacca acccaaacag ctagaaagtg
    15841 accatacagt agatacagaa acgatggacg aaatcactag ctttttagaa acgttcttcc
    15901 agctctatcc taccgccaca gaaaaagaat tgacttacta tgtaagtaat catgtgttac
    15961 ctatgattaa caaggaatat gttttcgagg aattggtgaa tcctatcttt accagaaaag
    16021 ataaccaagt aatcgtgaat gtcgctgtga aatatttaga tcaagaaaca aaggcaaccc
    16081 aaatctcgca atttgagttg atattagaaa aacaagataa ttggaagatt gtaaaataac
    16141 aaatattggt acatgattac agatactttg taatcatgta ctctttttga taaaaaattg
    16201 gagattcctt tacaaatatg ctcttacgtg ctattattta agtgactatt taaaaggagt
    16261 taataaatat gcggcaaggt attcttaaat aaactgtcaa tttgatagcg ggaacaaata
    16321 attagatgtc cttttttagg agggcttagt tttttgtacc cagtttaaga atacctttat
    16381 catgtgattc taaagtatcc agagaatatc tgtatgcttt gtatacctat ggttatgcat
    16441 aaaaatccca gtgataaaag tatttatcac tgggattttt atgccctttt gggtttttga
    16501 atggaggaaa atcacatgaa aattattaat attggagttt tagctcatgt tgatgcagga
    16561 aaaactacct taacagaaag cttattatat aacagtggag cgattacaga attaggaagc
    16621 gtggacaaag gtacaacgag gacggataat acgcttttag aacgtcagag aggaattaca
    16681 attcagacag gaataacctc ttttcagtgg gaaaatacga aggtgaacat catagacacg
    16741 ccaggacata tggatttctt agcagaagta tatcgttcat tatcagtttt agatggggca
    16801 attctactga tttctgcaaa agatggcgta caagcacaaa ctcgtatatt atttcatgca
    16861 cttaggaaaa tggggattcc cacaatcttt tttatcaata agattgacca aaatggaatt
    16921 gatttatcaa cggtttatca ggatattaaa gagaaacttt ctgccgaaat tgtaatcaaa
    16981 cagaaggtag aactgtatcc taatatgtgt gtgacgaact ttaccgaatc tgaacaatgg
    17041 gatacggtaa tagagggaaa cgatgacctt ttagagaaat atatgtccgg taaatcatta
    17101 gaagcattgg aactcgaaca agaggaaagc ataagatttc agaattgttc tctgttccct
    17161 ctttatcatg gaagtgcaaa aagtaatata gggattgata accttataga agttattact
    17221 aataaatttt attcatcaac acatcgaggt ccgtctgaac tttgcggaaa tgttttcaaa
    17281 attgaatata caaaaaaaag acaacgtctt gcatattaag tagttcagtt ttggagtaca
    17341 aaaagtgaaa atgtaaacct aaatgagtat caaattgcaa ctgaatttga tactcgtttt
    17401 ttattgttaa atcaacgttt gttgttaatt tacaccacaa aatgtaagtt aaaatgtata
    17461 taaaaatgcg aacgtgaaat aattattgta ggaatgcaaa ttggtgtgtt aaaatggtta
    17521 caatttacta agcaaaaagg ggtgcatttt cctatgcaat ttcttgagcc aaaaaataag
    17581 aacgctaagt ctgtggattg ggaaatatca gagcaagtaa gggtgatagt taagcaatac
    17641 gctgaatatg cagagcgtac tgaaagcgaa gcagtggatg aattcttatt gaacatttta
    17701 gacgataaga agtttattga atggattgcc aacaagcgaa gtaataagcg gattgttgaa
    17761 aaaatgggta tcaaagatag agtgggttga tagacaatga ccaagcttaa aagattagcc
    17821 acgaaggaag atgaaattgt agatgttaaa attccgattt caaacgaaga attaaaagat
    17881 agggctaaac aatatgattt attaactcca aaacgatttg caacaaggta taacaaaatg
    17941 ttgttcttgc caacgtcttt taaatggaac ggttctgaat atcccattca atataattac
    18001 tgcatcaatc cgttttgttg taattttggg aaagaacagc acaaattcaa agatgtaaaa
    18061 gggaaaccaa gtcgatataa aatgactggt agttccaaag ataaaggtca taaaggtatg
    18121 tactgcaatg acaatcctat tggcagaggt gtatcgcaaa actgtacagt aaccccttta
    18181 tctaattggt ctgttgttga agaaattaaa cgccttatag aaatcaatag catccaagat
    18241 gttgagccag attatcaatt tcataaagaa ggctgctcgg aagaagaatc aaccccattc
    18301 aatgagccga agcaatttta caaaaggggg aaaagtaggg gcaaatctca acgctatcaa
    18361 tgtaaggcgt gtaagaagtt cactaatgtt ctaccaaaaa gagaagaaac cactacttat
    18421 caccaacaaa agaacaccat tcttccaatg ttcgctaaga tggttgttgg aagggtttca
    18481 gtcagtcgta cttgtgatat tttaggaatt ggagttggaa cctactatca taagctggag
    18541 tggctgtata ggcgttgttt ggagttttta gaacgatatg agacacaacc ccttcaaaca
    18601 aagaaattta acgagatgtg gcttaatacg gacaagatgc actactacct aaataacgtc
    18661 cgtaagaaag gacaaggttc aaagaaatat acggggtttg aagaccttaa tatgcaaacg
    18721 tatatagttg tatctgctga ggtcttatca agatatgtgt tccgttctga tgttgcctat
    18781 gattggaata tttcaatgga tgaattaaat gaagatacaa gaaaattcaa agaagaccat
    18841 ctcaatactt ttagtcgtaa aaatgatagg ttagattggt cttattatcc acaagaacca
    18901 tccgctaacg atagcgaaaa taggaatgct tatcttcacg aattagggaa aattactaat
    18961 aggagtagat ttgtcgatgg tttaaatgtt gatgctcctt atactacaac tgctcactat
    19021 tggttaatta aacaaatggt taatgccgac gaatggcgaa tgattagtga tgatgacttc
    19081 tctattagaa acgcctttta tagagtattc acgaaagaat taaggttgag cgatgcacat
    19141 cattttattt gccaagttaa caagacgaaa agcagaaaac aatgcttaaa agaattcgga
    19201 caagcaaaag cagaactgct cgattgggga gatatcagag gattcaaaac aaagtttcta
    19261 cggactttgg catctcatta tctaactgaa ttactaacaa gtcatcaatt ccacgaagag
    19321 gctattagta aagatggaga aagatatcgc aaatatgccg ataaccctat caaacatcca
    19381 ttagccacta aggataaagg attttattca gttgattgta gaacggattt atctgctctg
    19441 gaaccaaacg aaatcgcaaa gatgctatta aatgttaatg accattcgac caatagcttt
    19501 attcaacaga taagacgtta tatatcatct cttgaaagac cattaacaac agctcgtggt
    19561 gataagaaga gctatattta cgctaacttc aatccgaagt atgctcaatt tgcgattaca
    19621 attctaagaa cttactacaa cttttgtcgc ccttttaaat cagcggataa aaaggttttg
    19681 acacctgctc aaagattagg gattacagat aaacaatttg attggaaaga tataatttat
    19741 ttcaaatgac aaaaagagct tggagtaatc ccaagctctt gtgctttatc tttactgttc
    19801 ttcttcaatt aacgcacccg ttaactcaat aagttttttc tttcatatac atgaaaatag
    19861 tagttatacg gatttttatc attctttatc cctttttggg caaatacctc attccattcc
    19921 tcataattca cttctggaaa aaaagtatct ccttcgaatt catgatgtat ttttgtgatg
    19981 tacattttct caacataagg gaaaaacaaa ttataaatct gttctcctcc gaaaataaaa
    20041 atttcttctt cgtttttaca taactcaaaa acatcttcta ttgaatgaac aatttcacaa
    20101 ccattaaagg taaacccctt atctctcgtc agaataatat ttcttctgtc aggtaaggct
    20161 cttccgattg attcaaggtt cttcctacct aatattatcg gatgtccctt tgtagtattt
    20221 ttaacatatt cccagtcctt gggaatcctc caaggaatgt cattctcttt gccaatcact
    20281 ctattcttat ccatcgcagc aatcaaagaa actttcattt ataacacagc ctttttaact
    20341 aatttaccat ctaatttctt atttctatca aaaaaccttt tctcattatc ctgcccgtta
    20401 gttgaataag caattttttc tataagttat attatcataa taccacaaaa tcacaaattt
    20461 tcattcaatt atcattttca attgcatttt ataaatcatt ttgtatgtaa tttggtatgt
    20521 aagttaaaat gaaaaaagta gtccattttg aagtacattt tgtcattttg tactccaaaa
    20581 ctgaactact tacttgcata tatacgcctt tatagtggag tactacattt acgagattcg
    20641 gttagagtat cagaaaaaga aaaaataaaa gttacagaaa tgtatacttc aataaatggt
    20701 gaattatgta agattgatag agcttattct ggagaaattg ttattttgca aaatgagttt
    20761 ttgaagttaa atagtgttct tggagataca aaactattgc cacagagaaa aaagattgaa
    20821 aatccgcacc ctctactaca aacaactgtt gaaccgagta aacctgaaca gagagaaatg
    20881 ttgcttgatg cccttttgga aatctcagat agtgatccgc ttctacgata ttacgtggat
    20941 tctacgacac atgaaattat actttctttc ttagggaaag tacaaatgga agtgattagt
    21001 gcactgttgc aagaaaagta tcatgtggag atagaactaa aagagcctac agtcatttat
    21061 atggagagac cgttaaaaaa tgcagaatat accattcaca tcgaagtgcc gccaaatcct
    21121 ttctgggctt ccattggttt atctgtatca ccgcttccgt tgggaagtgg aatgcagtat
    21181 gagagctcgg tttctcttgg atacttaaat caatcatttc aaaatgcagt tatggaaggg
    21241 atacgctatg gttgcgaaca aggattatat ggttggaatg tgacggattg taaaatctgt
    21301 tttaagtacg gtttatacta tagccctgtt agtactccag cagattttcg gatgcttact
    21361 cctattgtac tggagcaagc ctttagaaaa gctggaacag aattgttaga gccatatctt
    21421 agttttaaag tttatgcacc acaggaatat ctttcacggg catataacga tgctcccaaa
    21481 tattgtgcaa atatcgtaaa tactcaactg aaaaataatg aggtcattat tattggagaa
    21541 attcctgctc gatgtattca agattatcgc aatgatttaa ctttttttac aaatgggctt
    21601 agtgtttgtt tagcagagct aaaaggatat caggttacca ctggcgaacc tgtttgccag
    21661 acccgtcgtc taaatagtcg gatagataaa gtaagatata tgttcaataa aataacttag
    21721 tgcgttttat gttgttatat aaatatggtt tcttattaaa taagatgaaa tattctttaa
    21781 tatagatttg aattaaagtg gaaaggagga gattgttatt ataaactaca agtggatatt
    21841 gtgtcctatt tgtggaaata aaacaagact acgaatacga gtggatacta tacttaaaaa
    21901 tttcccttta tactgcccca aatgtaagaa cgaaacttta attaatgttc aaaaaatgaa
    21961 tataataaca atcaaagagc cagacgccaa gacgcagagc cgataatttg agaaatgaaa
    22021 ctctcatctt atcggctctt tttgtttatc tgaattttac tgactagcct tcaatatttc
    22081 ttgcttcatt gatacctttt gctagtgctt ccattaagga tagttctttg tctgtaaagc
    22141 tatccatgta tttttctacc tgtaaccttc gagtgctttt aatcaaatta tctgtaggta
    22201 agaaaaattc atcaatagat acatggagta atgatacaag atcatacagc acttgtgtac
    22261 ttgggtgttg tcctttgttt tctatatttg ttaaataacg tgggtcaatt tcaatcattg
    22321 ttcccacttg ttcacgagtg agaccccgtt tcattcgagc ctctttaatc gctaaaccaa
    22381 cggctctaaa atcgtattta tcttcttttt tacgcatact aaatcacctc tatacatttt
    22441 actgttccta tataaccata aacaggtata gaaaaacatg ttatatagtt tatgagttcc
    22501 tatagaacac tgtggaattt attaatgcga tgaatccaat ttcaaataga aaggtcgctg
    22561 attttattta cctatacaac tttataaaat ttagtcatac tcctagaaag tagataaaat
    22621 tggcgactta atggagggaa aagtcgccat gagaaagata atctgtcatc tagttctctt
    22681 aattaagttc ttatcaaaaa aacttatcca cctgtactgg atagatatga ccatcaatgt
    22741 ggttttgcag attacataga tagaaaaatc aaagcatatg aacagagaaa acaatctgtt
    22801 tatgtgcttt tttggtcact taataaatat cttttaggat ttctcttcat ttatgcaaca
    22861 aatcccccgt tcgtgtcggg gtttagtatg aagggagata aagaagcaca tgccactccc
    22921 tttcacgaca gaaagggggt gaaaagcatg aaaccatctt cttttcaaga aaccatagaa
    22981 aatcagtttg actatatctg caaacaagtt attgaagatg aacgaaaaga ttacttcaaa
    23041 catctagaca gactatcagc aaaagaagtc tcgttttctg atatagataa ctaccttgtc
    23101 aactcttttt ctactgttga tacgtacgtc actgatttcc aactatttaa attatttgga
    23161 ttaagaatca atgttgaaag tgatttatta agtgaagccc tgcgtcatct ttcagagaaa
    23221 aaacggaaca ttattttact tcattacttt atggatatga gtgatgtgga gattgcggag
    23281 ttactaaatt tgaatcgttc gactgtttat cgtcatcgaa taagtggact agccatgatt
    23341 aaagaattca tgaaggagtg taaagaatga aaacagctta tccaagggtt cccttccccc
    23401 tcattgtaaa ggcgacagat ggcgacgtgg aagcaattaa tcagattgtt aaacattatc
    23461 gagggtatac ctcaaaacgt tcattacgtc gcatgacaga cgaatatgga aattctcata
    23521 tggttattga tgaaacccta cgtggcagaa tggaaacgaa actcatctct aagattttat
    23581 cgttcgaaat taaatagtcc cattttttcg tggaagcgtg tcgaatcgta tccacgcttc
    23641 ccgatttggg aggtttgtta ttccatcaaa gcatattgtg tgttcagtag gttttgatag
    23701 gctaacaagc caaacgttct ttgacaacca aataaaggca atcgaatacg tttcggtaag
    23761 aaaagagctg atgaactaac acgccatgac ctacaaaatt agtgagcgat tcatgttagt
    23821 aattcgaaag taatctttag caggattgct gccatgactt tcttatcgtg ataatgatac
    23881 tcccgtatag ccatagtccg agcgttagaa gcgtcacagg caatgggtac ggctacatga
    23941 gaaccatgca gaagtgaaat tcctgtgagc tttgctagag ctgttcgatt gctaagatat
    24001 tcttctcttg tcagtgtatt attataaaac tatttgatat aattataggt gaatattgga
    24061 gttttcctag cctataattg ggaaaggagt aataatgata acggtcacaa aaaaggattt
    24121 agttgagcta ggatatggaa cttctttttc agcagacatc ataaaaaaag caaaagaatt
    24181 gatgattaca aaagggcata tctactatca atctcgaaag ctagatagag tccctcgtga
    24241 agctgttgaa gaaattctag gaattcggtt ttcaaatgaa aacaggtctg agtagttttt
    24301 gcacagtaag gagtaaaaac tatggttaaa gacccaataa aaaaagcaaa gaatggaacc
    24361 tattattttc gtgcaaatct aggttatgat tctaaaggga aaaaaattca aaaatatcgt
    24421 agtggattca ctactaaaaa agaagcaaga gaagaatatt cgaaactgct attgatgaaa
    24481 ccagaagaat taagtgagaa taaggataaa atgacgttta aacattatat ctttgaaatt
    24541 ttccttccat ggtataagac acaggtaaag ctcagaacat atgaaaatcg cttaccaact
    24601 attaagaagc atttctctta ttttgataaa atggctgttt ccgatattga gcctattgat
    24661 gtgcaaaatt ggcaactaaa attatcaaag aagtgtaagt cttcttatgt aagagctgtt
    24721 caaggactat tttcagttgc tatggatcga gcaattgtcc ttgggataac caccacaaat
    24781 ccatctaaga ttattggcaa tgtgaaaaag caaaagtcta aaattgaatt ttggacaaaa
    24841 gaagaatttg aaaaagtaat ctctctaatt tacaaagaag attactatca acacttttta
    24901 tttatctctc tgtggttttt atttatgact ggaatgcgaa ttggtgaagc tactgccatt
    24961 caatgggaag atattgattt tgactcagga gtactaacca tcaacaaaac actctattac
    25021 aagaatcaat cgaattatag atttgttgaa ccaaaaacaa aggcgagcgt tcgtcatatt
    25081 gtattagata aatgcacatt aacttattta tccgaatgga aggaagtaca acaaaatcta
    25141 attcagacag actttgtaat gagctataac ggtattccta cccaaaaaca tacactatca
    25201 tatgctattg aacgctatgc taagctggct ggtatccatc gaatcagaat ccatgggtta
    25261 cggcattctc atgcttcctt gttaatcagt atgggagaaa atccacttat cattaaagat
    25321 cgtctaggac acgaagatat tgagacgact ttaggaacgt atggacatct ttatcctaac
    25381 agtaatttcg aggtagctaa caaattaaat ggagccattt cctttaaaga agcaaaacaa
    25441 aattatgata cttcaccaaa gaatcaattt actgtagact acttgcgaaa caaagaaatg
    25501 aaaaaagtgc aataaaagtg cagtaaaaag ataagaagag ccagaaaccc ttggtataag
    25561 aggatttcta gctctcctac aactattccc actccactgt tgctggtggt ttagaagtga
    25621 tgtcatacac gatacggttg acgtgggcta cttcgtttac gatacgtaca gagatttttt
    25681 gcaagacttc ccatgggata cgggcaaagt cagcggtcat tccgtcgatt gaagttacag
    25741 cacggatacc gactgtgtag tcgtaagtac gtccgtcacc cataacaccg acagagcgga
    25801 tccctggaag aacagtgaaa tattgccaga tatcacggtc aagtccagca gctgcgattt
    25861 cttcacgcaa gatagcatca gattcgcgta cgatttctag cttgtcttca gtgatttcgc
    25921 caagaacacg aataccaaga ccaggaccag ggaatggctg acgccaaacg attgaatcag
    25981 gcatgcctaa ctgagtccct aattcacgga cttcgtcttt gaataatgtg tttaatggtt
    26041 cgatcaattc aaattgcata tcttctggca gtccacctac attatggtga gatttgatcg
    26101 tctgtgctgt ttctgtacca gattcgataa cgtcagtata caacgttcct tgtgctagga
    26161 aagagacgcc ttcttcacca gcaagttttg ttgcttcgtc atcaaaaaca tatacgaatt
    26221 cattcccaat gattttacgt ttttgttctg ggtcagatac acctttcaac ttgtctaaga
    26281 agcgatctct tgcatcgact ttgatgatgt tcaagccgaa ttttccgcct agactttcca
    26341 ttacttgttc cgcttcgcct ttgcgtagca gaccgtggtc aacaaagata gatgtcaatt
    26401 ggtcaccgat cgctttttgt aaaagaaccc caacgacact agaatcaacg ccacctgaaa
    26461 gaccaagcaa gacttttttg tcaccaactt gttcacggat tttttctact tgcatatcga
    26521 taaagttatc cattgtccag ttaccttcac agtgacaaac atcaaaggca aagtggcgca
    26581 gcaattcgat tccgtattcg gaatgacgta cttctgcatg gaattggata ccataaaaat
    26641 tacgtgttgt gtcttggata gaagcaatcg gacaatcttt gcttgttccg actgtttcaa
    26701 agccttcagg aactttagtt accaagtcac catggctcat ccatactgtt tgttgttttg
    26761 gtgtttcttt aaacaagaca gcttgatcgc ttgttacttc taacaaggct ttcccatatt
    26821 cgcggttttt agcaggctct acggaaccgc caagtttgta cgtgatcaat tgcataccat
    26881 agcaaatccc taatacagga atacctaaat tgaagatctc aggatcgatc ccaaatgcat
    26941 tctcatcata tacactgttt ggtccgccag aaagaatgat tccctttgga ttcatcgctt
    27001 ttacttcttc tgcagtaatg cggtggctca ataattcgga aaagactcca agatcacgaa
    27061 tacgtcttgt gatcaattgg ttatactgac taccgtagtc taatacgata atcttttcaa
    27121 cgttcgtcat atcggcaacg tttgtcaaat ttattacccc tatcccttta aattttatct
    27181 caaaatagtc aaactatttt aaaatgctaa tattttcgca tgaaaatcga atcgatgata
    27241 tgattttcag ttttatggag aattatatcg gctcttcctc gtgtaggcaa gatatattcc
    27301 tgtaaatttt tcaaattcac atttttccat acatcttttg ccattttaaa ggcttcttca
    27361 cgatctccga tagcaaaacg ataataataa ttctctggat tttggaaagc cgtatccagt
    27421 aacgcaccaa aacgatccaa ataccatttt tcgatcagca cgggatcggc atcgacatag
    27481 acagaaaaat caaaaaagtc gctgacgtag atttgctgat tcgcaggtaa ttgaagcgta
    27541 ttgatcccct caacgatcaa gatatcaggc tgctggatca attcgtactt gtctggaatg
    27601 atatcataca catcatgtga gtaaacaggt acttttatct cttcctgacc agattttaca
    27661 cggttcaaga aatcgatcag catctccata tcataacttt caggaaatcc tttacggtcc
    27721 atgattccac gctcttttaa tatacgattt ggataaagaa atccgtcagt cgtgatcagc
    27781 tgaacgtttc ttcgtttgaa ggtacgagac aaaatcgtct gcagcagtct ggctgttgta
    27841 ctttttccaa cggctacact tccggcgatc ccgataataa aaggcggtac ttctacgtat
    27901 ttatgaagaa ataaaccttt actcaagaac aaagattcaa attctttcat ataaagataa
    27961 atcagatgag caagaggtac atagatatct cgaacatcct gcatggaaat gcggtcattc
    28021 aaacttttga tattatctag ttcatcttgt gtcaaaggtg cttgcccatt acgataaaat
    28081 tctcgccatt cttctcttgc cacacggtag tagttcattg gatcattcat attagcctcc
    28141 tgcgttctcc catcaatgga actattttaa cacaaaataa acgcaaaccc caccacttaa
    28201 gagagattgc cgatcttttt gtataatctt tataatagaa agaaacggag tcttattctt
    28261 gacttgcgca cggatacata aaaggataga ctgttgtcat gaaagaaatg agaaggatgg
    28321 aagacatgac aaatcattac tattctgaac gcccagatac ggcgcacgat tttgaacaat
    28381 gggcttttga gttaaaaggc agaacctttc aatttgtaac agattctggt gtattttcac
    28441 gtgaaacagt ggattatggt tcacgtgtcc tgattgatgc tttcgattgg gaagagttac
    28501 ctgatgaagg aaagatctta gatgtgggat gcgggtatgg accgattggg ttagctttgg
    28561 catttgcgac acagcggttt gttgaaatgg tcgacattaa tgaacgagcg gtaagtctag
    28621 cgcaaggaaa cgcaaagcgt aaccaaatcg aacatgttga tatccatcaa tcgaatatct
    28681 atgaagcagt tcatgaagaa acctatgcag ctatcgtaag caatccgccg atccgtgctg
    28741 gaaaaaaagt tgtacatgaa attttgacag gcgcatatcc tcggttgaag aagggcggta
    28801 cactgacaat tgtgatccag aagaaacaag gagcgccgag tgcgcaaaag aaaatggaag
    28861 aaacatttgg taatgcagaa atcgtcacaa aagataaagg atattatatc atcaaaagtg
    28921 tgaaagaata actagctgaa aaatagtgga gcgacgaaag agtggaactg ggcgtgcatg
    28981 tacgggtacg tatcagttct ttttttgttg agaagttttt aaaaacaaag aactattttt
    29041 tcttcaaaaa gaaatagtag gaacagagtc gttgtttttt acgataaaat aaataagata
    29101 cagaacttgt atagaaggct gccaagtcgg tagataaagg aggtttttat caaaaaacat
    29161 actttccttt tttctctatt cttttcttgg gggttttggt acactgatag ggaatttaga
    29221 tagaagggag ccaataggat gaagctgacc atcagagata tcgcagaaat ggcaggcgta
    29281 tcagtaacaa ctgtctcaca gattttgaat aacaaaggaa gcagatttag tgataagaca
    29341 agaaaaaaag tgttgtcgat cgtgaatgaa catcattata agcccgatta tttcgcttca
    29401 aatgtgatca atcgacattc aaagaccatc ggaatgatcg tccctgatgt cactgatttc
    29461 ttcttctcca aactgatcga aggtgtagag agctatttga atcctttggg ctatgtgatc
    29521 atgttatgca attctcgtca tagccaagaa aatgagatca agtatttaca agagctttcc
    29581 caccgctcag tggacggaat cttgctggcc acaccaaata ttttacctga gaaatatgca
    29641 ttagacagcg gtttttatca aaaaatgcca atcattttaa tcgatcgcgg attgaatcgt
    29701 cgggataacg gacggcttat cgtaaaggaa tatgagggcg cctatcaagc tgtttcgctg
    29761 tttattgaaa atggccatac gaagatcggc atgctgaagg aaaccactgg atactatcaa
    29821 ttagaagaac gtttcaacgg atatcgtcat gcgctgaaag atcatggcct gccttttaat
    29881 gggaaatttg ttgaacatgg agagttgact gtccaaggtg gatatactgc atcaaaaaaa
    29941 ttactcaaac ataaagatat cacggctatt ttttgcggga atgatgccat ggcgatcgga
    30001 tgctatcagg cgatcgatga attgggcaaa aaaatcccag aagatatctc agtcatagga
    30061 ttcgatggat taaagctgtc agaatacatg attccgcaat tgacgacagt gcagcagcca
    30121 agttttgata ttggatttta tgctgcacgt ttcctgatcg atacgatcga atttcctcaa
    30181 agaaaagttc cgaacaaagt gttcgaaaca aaattaatta ttcgtgagag cgtaaaagta
    30241 ttgacaaagg gctaactcgg cggtatattg cttatgtaag catttacaaa ggctagttag
    30301 tgcttttttt atttttagta aaccagttta ctaaagtggt ttacctttcc taaaaataat
    30361 gtataatacc gaatgaagac aaggaggatc aggcaatgcg aatggtggat ctgattgaaa
    30421 aaaagaggga tggaaacgag ctgtcgaaag aggaaatcga gtacatcgtc acgaactata
    30481 cgaatggaaa gattccagat tatcaagtca gtgcattatt gatggcaatt ttttatcaag
    30541 acatgacaaa tgaagaaatc acgaacttaa cattggcgat tgctaattct ggtgatgtca
    30601 tcgatttgag ttctcttgaa ggaataaagg tagataagca ttcgacaggt ggcgttggtg
    30661 acacgaccac attgatttta gcccccctag tagctagtgt cggagtgaca gtggctaaaa
    30721 tgtctggacg cggtctaggt tacacaggtg gtacactaga caagctagaa gcaattcccg
    30781 gatttcagat cgagctttcg gatgaagaat ttgtacgcat tgttaatgaa agtaaagtag
    30841 cggtaattgg tcaatcagga aacttggcac cggcggacaa aaaattgtat gccttgcgtg
    30901 acgtcacagc gaccgttgat tctcttccgc tgattgccag ttcgattatg agtaaaaaaa
    30961 tcgcggcagg agcagatgca atcgttttgg atgtgaccac tggagacggt gctttcatga
    31021 agaacatcga agatgcaaga cgtctggcaa agaccatgac gagcattggg aaactggcta
    31081 accgagaaac agtggcggtt atctcagata tgtcagaacc tcttggcgaa gctatcggaa
    31141 atagtctaga agttgtcgag gcaatcgaaa cattacaagg aaatggtcca gaagatctag
    31201 tagaaatgtg ctacgcctta ggaagccaaa tggttgttct tgctggcaaa gctaagacaa
    31261 ccgatgaagc aagaacgttg cttcaagaag ctctggaatc aggtaaagcg ttagcaaaat
    31321 tcaaagaaat gatccaaaat caagggggag acccagcgat cgtggaacat ccagaacgaa
    31381 ttttgactgc acgctacaca atggagcttc ctgctaaaca aagcggagtt gtgtcaaaaa
    31441 tcgtggcaaa tgaattagga attgctgcaa tgatgctagg tgctgggcgt aaaaccaaag
    31501 aagaagatat tgatcacgct gttggattga aactgcataa aaaaattggt gacactgtga
    31561 caaaaggtga gtcactattg acgatctata gtaacgacga agaaatcact tctgtcattg
    31621 aattattata taaaaatatt gaaattggtg aatcggcaat gaagccaacg ttgattcatg
    31681 acatcatcac agaataaagg aaaaaagcgg actttaccgt tttaaagaaa aggggaaaag
    31741 aaatggaact aaaccgaatg atcgaccata ctattttgaa agcagacgca tctaaagaag
    31801 ctgtgatgca aattatcgaa gaagcaaaaa aataccattt ttattctgtc tgcatcaatc
    31861 cagcatgggt tgcgctagcg aaagaacaat tacaaggtga gccagtagcc gtatgtacag
    31921 taatcgggtt tcctctagga gcaaacacac ccgagacaaa agcatttgaa acaacagatg
    31981 ccatcaataa cggtgcagat gaagtcgata tggtcatcaa tatcggtgct ttgaaatcaa
    32041 aggatgatca acaagtccaa aaagatatcg aagcagttgt tgaagcagca aaagatcgtg
    32101 cgcttgtcaa agttattatt gaaacatcgt tattagatag agaagaaatc atccgagctt
    32161 gcgaaatagc aaaagctgca ggcgctgatt ttgtcaaaac atcaactggt ttctcaacag
    32221 gcggagcaaa ggtagaggat gtccgtttga tgcgtgaaac tgtaggacca gaaatgggtg
    32281 tcaaagcttc cggcggtatc cataacgaag aagaagcaat ggcaatgatc gaagctggtg
    32341 ctacaagaat cggaacaagc gcaggagtag caatcgtatc tggttcaact ggtgaaggct
    32401 attaattttt tcaaaggaga agctcatggc agaactcaaa caagaatgga tcaacacagc
    32461 tattgaagcg ttagataaag cctatgttcc ttattcccat tttccggtag gcgcttgtct
    32521 cgtaacggaa tcaggcaaga tttatcaagg catcaacatt gagaatgcat catttggatt
    32581 aacgaattgt gccgagcgca cagctttttt caaagcagta tctgaaggag aaaaaacatt
    32641 tacgcatcta gtcgtagcgg ggcacacccc cgatcctatc tctccttgtg gtgcatgtcg
    32701 acaagtaatg gcagaattct gttcccctga tatgccggtt acgctagtag gagacaatgg
    32761 tgtgacgaag gcaacgaccg ttcgtgcact gctgccttat gcatttactg aaaaagatct
    32821 ataactcatg ttcattcagt cagctgactg ttgaaaaata aaacaattat tttaggaggc
    32881 tttacagaaa tgaaaaaagc aaaattattt ggtttaggtg ctgtcgcact agcagcaggg
    32941 ttatttttag gtgcatgcgg caacaacggc tctactgatt catccggtgg caaaagctca
    33001 tcagacacaa caactgcagc attgatcaca gacacaggtg gtgtagacga ccgttcattc
    33061 aaccagtcag cttgggaagg actagaaaaa tgggggaaag atcaaggact ttcacgagga
    33121 aatgatggct tccaatattt ccaatcttca aatgaatcag attacatccc aaatattgac
    33181 caagcattga atgctggatt caaaacgatt tttggtattg gttataaact aaaaccagcg
    33241 atccaagaac aagcaacaaa caatacaggt acgaactttg ttattatcga tgatgtcatc
    33301 gatggattag ataacgttgt atctgcaact ttcaaagaca acgaagcttc ttatcttgca
    33361 ggtgttgcag cagcttatac gactgaaaca aacgtagtcg gctttatcgg cggtgtaaaa
    33421 ggtgaagtaa tcgatcgttt tgatgctgga ttcaaagccg gtgttgatgc aggtgcgaaa
    33481 gaattaggaa aagaaatcaa agtattgaat caatatgctg gtgacttctc tgctccagat
    33541 aaaggacgtt caattgctca aggtatgtat gcacaaaacg cagatatcat cttccatgct
    33601 tcaggcggta caggtaacgg tgtattccaa gaagcaaaat cattgaacga atcaggcgac
    33661 aaaaaagttt gggttatcgg tgttgaccgc gaccaatcag acgaaggcga atacacatta
    33721 aacggcgaaa agaaaaactt cacattgaca tctacactga aagcagttgg aacagtagta
    33781 gaagatttgg cacaaaaatc agcggacggt aaattccctg gcggcgaaca cactgtttat
    33841 ggattgaaag aagacggtgt tggtctaaca gaaggacaac tttctgacga agcgaaaaaa
    33901 gcagttgatg aagcaaaaga aaaaatcatt tcaggtgacg taaaagttcc agaaactcct
    33961 gaagaaaact aaaaccattt ctatagcctt gttagacaca tgtttgacaa ggctatggtt
    34021 tgattagaac aagaattgtt catttatcca agctgccttg tgacagtttg gataagggaa
    34081 caactccctg aagtaatgtt tgtttcaaaa gaagaacgct cactaagcgt gaatcttagt
    34141 caatcgttgc cctagataga aatcgttagg atgtgaaaaa aaggtggttc aagaaaatat
    34201 tgtcatagaa atgcagaata ttaccaaaga atttggaaca ttcaaggcaa atgacaacat
    34261 caatttacaa gtaaaggcag gagaaattca tgcgttgctt ggagaaaacg gtgctggcaa
    34321 atctacattg atgaacgtgc tttccggatt attagagccg acatcaggga aaattttgat
    34381 gcgtgggaaa gaagtaaaga tcacaagtcc gaccaaagcc aaccaattag ggattgggat
    34441 ggtccatcag cactttatgc ttgttgatgc ctttactgta acagaaaaca tcgtgttggg
    34501 aagcgagcct agtcgcgcag ggatgcttga ccataaaaaa gcacgaaaag agatccaaaa
    34561 agtttctgaa cagtatggat tgtcagtcaa cccagatgct tacgttcgtg atatttcagt
    34621 tggaatggaa caacgggtag aaattttaaa aacactttac cgaggagcag atgtactgat
    34681 ttttgatgag ccgacagctg tattgacccc tcaagaaatt gatgaattaa tcgtgatcat
    34741 gaaggaatta gtcaaagaag gcaagtcgat cattttgatt acgcataagt tagatgaaat
    34801 caaagcagta gctgaccgct gtacagttat ccgccgtgga aaaggaatcg gtacagtcaa
    34861 cgttaaagac gtaacctcac aacaattagc cgatatgatg gttggaagaa cggtttcatt
    34921 caaaacgatg aaaaaagaag cgaagcctca agaagtcgtt ttgtctattg aaaatctagt
    34981 ggtgaaagaa aatcgtggat tagaagccgt gaaaaacttg aacttagagg ttcgtgctgg
    35041 cgaagtactt ggtatcgctg gaatcgatgg aaacgggcag tcggagttga tccaagcttt
    35101 gactggtttg cgaaaggcag aaagcggaca tatcaagcta aaaggggaag acatcactaa
    35161 taaaaaaccc cgaaaaatca ctgaacatgg tgtaggacac gtgccagaag accgtcataa
    35221 atacgggtta gtcctagata tgacattatc tgaaaatatc gcactacaaa cctatcatca
    35281 aaaaccttac agtaaaaacg gcatgctgaa ttattcagta atgaatgaac atgccagaga
    35341 attgatcgaa gaatatgatg ttcgaacaac gaatgaactt gttcccgcaa aagctttatc
    35401 aggcggaaat cagcaaaaag caattatcgc tcgtgaagtc gaccgagatc ctgatctgtt
    35461 gattgttgca aatccaactc gtggactgga tgtaggtgcg atcgaattta ttcataaacg
    35521 tctgatcgaa caaagggaca aatacaaagc agtgttactg atcagtttcg aattagaaga
    35581 aattttaaat gtttcggatc gtattgctgt tatccatgaa ggagaaattg tcggtatcgt
    35641 tgatccgaaa gaaacatctg aaaatgaatt aggtctattg atggcgggct ataccttaga
    35701 agaagcacga aaagagttag aaaagggggc tggcgcacat gaatgatcgc agcgaaaaat
    35761 tccgtaattt attagtgcct gtactttcag ttgttttagg attgatctta ggcgcgatat
    35821 tgatggctgc ttttggtttt cagcccatcc aaggttattc ttctatgcta gatgcagccc
    35881 ttggttcgca aagagggata ggtgaaacgt taaggcaagc aacgccgttg atttttacag
    35941 cattaggttt ttctgtagct aactcagctg ggtttttcaa tattgggctt tctggacaag
    36001 cactttgcgg gtggatcgtc agtgtctggg tggcacttgc gtttccagat ctgccaaaag
    36061 ttgttttgct tccgttatgc gtgatcttag gtgccttagc tggtgcgatg gcagcggctg
    36121 ttccaggttt acttcgagca ttttttggaa caagtgaagt gatcgtaaca atcatgatga
    36181 actatatctt attatacgta agcacatttg ctttacatga agtgatgcct gaaagctatc
    36241 gctcaagttt ggactcttcc aatatgatca gtcaaaatgc ctcactgcgg ttaccatggt
    36301 taacacaagc ttttggcggc tctcgcgtaa actcaggatt atttttagca atcatcgcgc
    36361 ttattttcgt ttggctgctg atgaagaaaa cgactttagg atttgaaatc cgttctgttg
    36421 gattgaatcc ttttgcttct gagtatgcag gaatgagtag taaacgtacg atcgttttgt
    36481 cgatggtcat ttctggcgct ttggcagggc ttggcggtgt ggttgaagga ttaggaacgt
    36541 atcaaaactt ctttgttcaa acgacttcgc tatctattgg atttgacgga atggctgttt
    36601 ccttgcttgg ttctggatca gcaatcggta ttcttttatc agcgatcttg ttcagtattt
    36661 tgaagatcgg tggacttggc atgcagacag gagcaggtgt tccgtttgag atcgtcaatg
    36721 tatcgattgc tttgattatc ttctttgtcg ggatcaactt cctgattcgt ttcgtcatgg
    36781 ctaaagtctt ccaagggaaa aaacaagaag agatcgttgc gacaatagaa tcgaaaccaa
    36841 cgaatcaaaa ccatgaaggg ggcgaactat aatgtcgact atcgaattaa ttgccttgat
    36901 ccttacttct acactggttt attcaacacc gctaattcta acgtcactag gcggaacttt
    36961 ttctgaacga agcgggatcg taaacgtagg gctagaggga atcatggtca tgggtgcttt
    37021 tagttccatc gttttcaact tgacgatgag tccatcactt ggttctatga caccatggat
    37081 cgctatttta gtgggtggcg tcgtaggtat cctattttct ctgattcacg cagtagcaac
    37141 agtcagtttg cgtgctgacc atattatcag cgggacagta attaatctga tggcacctgc
    37201 tttaggtgtt ttcttgatca aagcatggta tggtaaaggt caaactgata acatcacgca
    37261 gaatctgggg tatttttctt tcccaggatt agcagatatt ccggtcattg gaccaatttt
    37321 ctttaaaaat acattcttac ctgcttattg tgctattttg attgctgtcc tagcttgggt
    37381 gatcatcttc aagacgaaat tcggcttgcg cctccgttca gttggtgaaa atcctcaagc
    37441 tgccgacaca ttaggtatca atgtatatgc tatgcgttat tcaggcgtac tgatttctgg
    37501 cttgttaggc ggtatgggcg gtgctgtttt tgctcagtcg atttccggta acttttcagc
    37561 tggtacgatc gttggacaag ggttcatctc catggctgct atgatctttg gtaagtggaa
    37621 tcctttaggg gcaatgggtg cctcattgtt ctttggtttt gctcaaagct tgagtatcat
    37681 tggcgcacaa ttaccagtta tttcttcgat tccgccagta ttgctgcaaa ttgctccata
    37741 tttgctgaca atcattgtgc tggttgtttt cttagggaaa gcttctggtc caaaagcaaa
    37801 cgggaagaac tatatcaaat caaaataatc ttttagcgaa taaaaagggt gggttacggg
    37861 aagtgttttt cgtctcgccc tttttgtttt aaaggcaata aaaataaaaa gaaagaagga
    37921 ataatcatgt ttaaacgcgt acatctgatc gtcatggatt cagtaggaat tggagaagca
    37981 ccagatgccg ataagttcgg tgatgttggt tctgatacat taggacacat tgcgaaagaa
    38041 gcaggattga acgttccaca tttagagcag cttggtttag gaacgatccg tcctcttgaa
    38101 ggtgtggaat cagtgaaaga tcatcaaggc tatgcgacga aattagaaga agtttctgta
    38161 gggaaagata cgatgacagg ccactgggaa atcatgggat tgaatatcaa aactccattt
    38221 cgtgtgtttc ctaatggatt ccctgatgat ctgatcaaac aaatcgaaga attttctggc
    38281 cgtaaagtcg tatgtaacaa accttatagc ggaacagctg ttattgacga ttacggtgaa
    38341 caccaaatga aaacaggcga tttaattgta tatacttctg ccgatcctgt ccttcagatc
    38401 gcggcacatg aagaaatcat tcctttagaa gaattatatc ggatttgcca attcgttcgt
    38461 gatataacaa aagatgatcc gtatatgatt ggccgaatca ttgcacgtcc gtacgtgggt
    38521 gaaccaggag acttcacacg aacaagcaat cgccatgatt atgcgttgaa tccattcgga
    38581 cacacagtcc ttgattcttt gaaagaagca ggaaaggacg tgattgctgt tggaaagatc
    38641 aacgatattt tcaacggaca aggaatcact gaatctgtcc gcacgaaaag caatatggat
    38701 ggcgttgacc agctgctgaa agttatgaaa aacgattttt caggaatcag ctttaccaat
    38761 ttagtagatt ttgatgcatt atacggtcat cgtcgggatg tagtcggcta tgcgcatgcg
    38821 attgaagaat ttgacttacg aattccagaa ttgcttgaag cgatggaaga agacgacttg
    38881 ctaatgatta cagccgatca cggaaacgat ccgacgttta ctggtaccga tcatacgcga
    38941 gaatatgtac cgttattggt ttacagtaaa aaaatgaaag aacaaggggc attgcctcaa
    39001 ggatattatt cagatatttc agcaacgatt gctgagaact ttagtgtttc ttcgactgaa
    39061 aatggcgaaa gcttcttgaa attattaaaa taatcttttt aaataggaga aagcaaatga
    39121 ccaagttaag cgagatgtta caagaaacga cccagtttat ccttgataaa ggagtaaaag
    39181 aaattgattt tggtttgatt ctaggttcag gattaggtga attagcagat gaaatcgaag
    39241 atgctgtaat gatttcttat gatgagatcc cgttctttcc tgtttcgaca gtagttgggc
    39301 atgcaggaaa gctagtttat gggtctctgg caggcaagaa agtgttagcc atgcaaggga
    39361 gattccacta ctatgaaggt cattccatgc aaacagtgac ctatccagta cgtgtgatgg
    39421 ccggactagg ggcccattca gtcattgtga ctaatgcatg tggtggtgtc aacgaatcat
    39481 ttgtaccagg agatttgatg ctgattaccg atcatatcaa ttttactggt gaaaatcctt
    39541 tgatcggtcc gaatgaagat gcaatgggcc ctagatttcc agatatgagt caagcttata
    39601 cgcctgacta tcaagcaaca gcaaaagcag cagcagaaaa actaggtttg gatcttaaag
    39661 aaggcgtata tatgggctat tctggaccaa cttatgaaac gcctgcggag atccgaatgt
    39721 ctcggacaat aggagccgat gcagtaggga tgtcgactgt tccagaagtc atcgtagcag
    39781 ctcacagcgg attaaaagtg ttaggaatct cttgtattac caacttagca gcaggtatgc
    39841 aagcgaatct gagccatgaa gaagttgtag aaacaactca gagagtcaaa caatctttta
    39901 aagcattggt taaagaaaca ttgacattat tgtaatagga ggaacaataa aatgagtgtg
    39961 catattgaag cgaaagaagg cgagatcgcc gataagattt tacttccggg agatcctttg
    40021 cgagctaaat atattgcgga gacttttttg gaagatccag tttgttacaa tcaggtacgc
    40081 ggtatgttag gctttaccgg caaatataaa ggagaacgta tttctgttca aggaacagga
    40141 atgggaatgc catcagccac catctatgcc catgaattga tccagtcgta tggtgtaaag
    40201 aaattgattc gagtaggtac atgcggtgca ttgtcaaaag acgtccatgt tcgtgattta
    40261 gtactagcac aaggtgcagc gaccagttct tcgatgatcg aaaaaaattt ccaagccttt
    40321 cattttcctc caatcagtga tttcaatcta ttactgaaag catatgagat agctaaagaa
    40381 aagggctata cggttcatgt aggaaatgtt ctttcggaag attctttcta caaagatgat
    40441 ttgacagaga cgttccaatt agctgaactt ggcgttttag gagtggaaat ggaagcagcg
    40501 gctctttatt acttaggcgc gaaataccat gtgcagacat taagtttgat gaccgttagc
    40561 gaccatttga tcaccggtga agaaacaaca gctgcagaac gtcaatctac gttcaatgaa
    40621 atgatcgaag taggattgga aacagcgata gcagaataag aaggaaatga aaaagctgcc
    40681 ctgcattaag taataagaac atccaagcaa aaatagctcc tcatgttttt gacttggctg
    40741 gacttattat tgcaaatgta agcttttgaa caccgtttac caagaggttg tgaatctgcc
    40801 gtttaactct gagtcacaag gaacaatttc aaaaaacagc tt
//
LOCUS       DACGMI010000023        40546 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.023, whole genome shotgun sequence.
ACCESSION   DACGMI010000023 DACGMI010000000
VERSION     DACGMI010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.023"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..197
                     /locus_tag="IXT46_001333"
     CDS             <1..197
                     /locus_tag="IXT46_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947257.1"
                     /translation="WFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLIIAIIAVGLV
                     FNAAGVKDILLELFNRIIGA"
     gene            314..811
                     /locus_tag="IXT46_001334"
     CDS             314..811
                     /locus_tag="IXT46_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAQ4947258.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            786..1292
                     /locus_tag="IXT46_001335"
     CDS             786..1292
                     /locus_tag="IXT46_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4947259.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            1276..3723
                     /locus_tag="IXT46_001336"
     CDS             1276..3723
                     /locus_tag="IXT46_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4947260.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENMPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            3726..5903
                     /locus_tag="IXT46_001337"
     CDS             3726..5903
                     /locus_tag="IXT46_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAQ4947261.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            5900..6901
                     /locus_tag="IXT46_001338"
     CDS             5900..6901
                     /locus_tag="IXT46_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAQ4947262.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            6898..7833
                     /locus_tag="IXT46_001339"
     CDS             6898..7833
                     /locus_tag="IXT46_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4947263.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            8078..8194
                     /locus_tag="IXT46_001340"
     CDS             8078..8194
                     /locus_tag="IXT46_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAQ4947264.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            8210..10129
                     /gene="tet(M)"
                     /locus_tag="IXT46_001341"
     CDS             8210..10129
                     /gene="tet(M)"
                     /locus_tag="IXT46_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAQ4947265.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            10248..10415
                     /locus_tag="IXT46_001342"
     CDS             10248..10415
                     /locus_tag="IXT46_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4947266.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(10475..10828)
                     /locus_tag="IXT46_001343"
     CDS             complement(10475..10828)
                     /locus_tag="IXT46_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4947267.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            11333..11755
                     /locus_tag="IXT46_001344"
     CDS             11333..11755
                     /locus_tag="IXT46_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4947268.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            11752..11982
                     /locus_tag="IXT46_001345"
     CDS             11752..11982
                     /locus_tag="IXT46_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4947269.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            12443..12646
                     /locus_tag="IXT46_001346"
     CDS             12443..12646
                     /locus_tag="IXT46_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAQ4947270.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            12728..13945
                     /locus_tag="IXT46_001347"
     CDS             12728..13945
                     /locus_tag="IXT46_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4947271.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            14251..15444
                     /locus_tag="IXT46_001348"
     CDS             14251..15444
                     /locus_tag="IXT46_001348"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAQ4947272.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            15574..17046
                     /locus_tag="IXT46_001349"
     CDS             15574..17046
                     /locus_tag="IXT46_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4947273.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            17129..17917
                     /locus_tag="IXT46_001350"
     CDS             17129..17917
                     /locus_tag="IXT46_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAQ4947274.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(17984..18652)
                     /locus_tag="IXT46_001351"
     CDS             complement(17984..18652)
                     /locus_tag="IXT46_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAQ4947275.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            18767..20479
                     /locus_tag="IXT46_001352"
     CDS             18767..20479
                     /locus_tag="IXT46_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947276.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            20482..22251
                     /locus_tag="IXT46_001353"
     CDS             20482..22251
                     /locus_tag="IXT46_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947277.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(22456..23022)
                     /locus_tag="IXT46_001354"
     CDS             complement(22456..23022)
                     /locus_tag="IXT46_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4947278.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(23022..23978)
                     /locus_tag="IXT46_001355"
     CDS             complement(23022..23978)
                     /locus_tag="IXT46_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAQ4947279.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(23978..24634)
                     /locus_tag="IXT46_001356"
     CDS             complement(23978..24634)
                     /locus_tag="IXT46_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAQ4947280.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            25004..27022
                     /locus_tag="IXT46_001357"
     CDS             25004..27022
                     /locus_tag="IXT46_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4947281.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            27449..29863
                     /locus_tag="IXT46_001358"
     CDS             27449..29863
                     /locus_tag="IXT46_001358"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAQ4947282.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            30211..31764
                     /locus_tag="IXT46_001359"
     CDS             30211..31764
                     /locus_tag="IXT46_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAQ4947283.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(32145..33929)
                     /locus_tag="IXT46_001360"
     CDS             complement(32145..33929)
                     /locus_tag="IXT46_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947284.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLYSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNFAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(33944..35665)
                     /locus_tag="IXT46_001361"
     CDS             complement(33944..35665)
                     /locus_tag="IXT46_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947285.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLQIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            35765..36526
                     /locus_tag="IXT46_001362"
     CDS             35765..36526
                     /locus_tag="IXT46_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4947286.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IRERKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            37494..37762
                     /locus_tag="IXT46_001363"
                     /pseudo
     CDS             37494..37762
                     /locus_tag="IXT46_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            38434..>40546
                     /locus_tag="IXT46_001364"
     CDS             38434..>40546
                     /locus_tag="IXT46_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947287.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTSNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATPIEFEIERSQTAVVELTK"
BASE COUNT        13102 a         7165 c         8416 g        11863 t
ORIGIN      
        1 actggtttct atcaaacgct caatcactgg tgcttttagc aatcgttgtg attggcttgt
       61 atcttggctt caagcgtgag tttagcaaac tgattggctt tttaattatt gcgattattg
      121 cggttggctt agtcttcaac gctgctggag taaaagacat tttactagag ctattcaatc
      181 gcattattgg tgcttaaata aaaccgttct tttgtggaat ataagtggtt ttcttatgtt
      241 ccgcaaagga atggtacacc aaacgaagtg cggtagggat ttttgaatct ctacaaagaa
      301 aggacgtgaa tatatggacg atatgcaagt ctatattgcg aatttaggca aatacaatga
      361 gggcgaattg gtcggtgcgt ggtttacctt tcccattgac tttgaggaag tcaaagagaa
      421 aatcggcttg aatgatgaat atgaggaata cgccattcat gactacgagt taccctttac
      481 ggttgacgaa tacacttcca ttggcgaact caatcgacta tgggaaatgg tatcggaatt
      541 acccgaagaa ttacaatcgg agctatctgc tctgctcact catttttcaa gcattgaaga
      601 actaagcgaa catcaagagg atattatcat tcattccgat tgtgatgata tgtatgacgt
      661 ggcacgctac tacattgaag aaacgggtgc tttaggcgaa gtaccagcta gtcttcaaaa
      721 ctatattgat tatcaagcct atggtcggga tttagacctt tcaggaacgt ttatctcaac
      781 caatcatggg atttttgaaa tcgtctatta aatctgtcgg tacattacta ctggcagatt
      841 ttctatttta cggggtggct caatcagcta cccctatttt ttatgaaagg attgattaca
      901 tgaagaaaat acgaagctat accagtatct ggtctgtgga aaaggtactg tattctatca
      961 atgattttag acttccgttt cccataacct ttacgcaaat gacatggttt gtcgtgtcac
     1021 tctttgcagt gatgatactt ggcaacttgc cccctctttc catgatagag ggagcatttc
     1081 tcaaatactt tgggattcct gtggctttca catggtttat gtctacaaaa acttttgatg
     1141 gtaaaaagcc ttatggattt ttgaagtctg tcattgctta tgcactgcga ccaaagctga
     1201 cctatgcagg aaaaaaagta acgcttggca gaaaccagcc acaagaagcc attacagcag
     1261 ttaggagtga attttatggc atatccaatt aaatacattg aaaacaatct cgtctggaat
     1321 aaagacgggg aatgttatgc ttactatgag cttgttcctt acaattactc atttctaagt
     1381 ccagaacaga aaatacaagt gcatgattct ttcagacagc ttatcgcaca aaatcgtgat
     1441 ggcaaaattc atgctttaca aatcagtaca gaatccagca tacgttctgc acaagagcgt
     1501 tccaaaaatg aagtcactgg caagctcaaa gcggttgcct atgacaaaat cgaccaacag
     1561 acagacgctt taatatccat gattggcgaa aatcaagtga actaccgttt ctttatcggc
     1621 tttaagttgc ttctcaacga tcaggagttt tctatgaaaa gtcttaccgt tgaagcaaaa
     1681 aatgctttgt ctgattttgt ctatgatgtg aaccataagc tgatgggcga ttttgttagt
     1741 atgagtaatg atgaaatcct gcgttttcag aagatggaaa agctcttaga aaataaaatc
     1801 tctcgtcgtt tcaaaatccg caggttagat aaggacgact tcggctatct gattgaacac
     1861 ctttacggac agacaggcac tgcctatgaa gagtatgagt accatctatc aaagaaaaag
     1921 ctggataatg aaacgctgat taaatactat gacttgatta agcctactcg ctgtttggtg
     1981 gaagaaaaac agcgatattt gaaaatccag caggaagatg aaaccgtcta tgtagcttac
     2041 tttaccatta acagcattgt cggagaactg gacttcccgt cctctgaaat cttctactac
     2101 cagcaacagc aatttacatt cccgattgat acgtcaatga atgtggaaat tgtagcgaat
     2161 cgtaaagccc tatctactgt ccgcaataaa aagaaagaac tgaaagactt ggataaccac
     2221 gcttggcaaa gtgataatga aaccagctcc aatgtggcgg aagctctgga aagtgtgaat
     2281 gagctggaaa ccaatttaga ccaaagcaag gaatctatgt acaagctgtc ttatgtggta
     2341 agggtatcag caaatgatct tgacgaactc aaacgtcgtt gtaatgaagt gaaagatttt
     2401 tatgacgatt taagcgtaaa actggtacga ccatttgggg atatgctcgg cttacatgaa
     2461 gaatttttac ctgccagcaa gcgttatatg aatgattata ttcaatacgt gacctctgat
     2521 ttcctcgctg gtttaggttt tggtgctact caaatgctgg gggaaaatga ggggatttat
     2581 gttggctaca gcttagatac tggacgcaat gtctatctga aacctgctct tgccagtcaa
     2641 ggggttaagg gttcagtaac caatgcgtta gcgtcggctt ttgttggttc gctgggtggt
     2701 ggtaaatcct ttgcgaataa ccttatcgtc tattatgcgg tgctttatgg ggcacaagca
     2761 gtgattgtag acccaaaagc agaacgtggc agatggaaag aaaccttgcc agagatttcc
     2821 catgaaatca atatcgtcac tctgacttct gatgagaaaa acaaaggctt acttgaccct
     2881 tatgtgatta tgaaaaatcc caaagattct gaatcactgg ctattgatat tctgacattc
     2941 cttacgggga tttcctctcg tgatggggaa cgcttcccaa tccttagaaa agccattcgt
     3001 gcagtaacca atagtgaagt acgagggttg atgaaagtga ttgaggaatt acgggttgag
     3061 aatatgccac taagtaccag tatagccgac catatcgaaa gttttacaga ctatgacttt
     3121 gcacatttat tattcagtaa tggttatgtg gagcagtcta tcagcttaga aaaacaactg
     3181 aacattatac aggttgcgga cttggtactt cccgacaagg aaacttcctt tgaggaatat
     3241 accactatgg agcttttatc cgttgctatg ctgattgtca ttagtacctt tgctttagac
     3301 tttatccata cagaccgaag cattttcaag attgtagatt tagacgaagc atggagcttt
     3361 ttacaggtag cacaaggaaa aacactatct atgaagctgg ttcgggctgg tcgtgctatg
     3421 aacgctgggg tatatttcgt gacccaaaat acagacgacc tcttagatga aaaactgaaa
     3481 aataacctcg gcttaaaatt tgcatttcgt tccactgacc ttaacgagat taaaaagacc
     3541 ttagcctttt ttggtgtaga cccagaggac gaaaacaatc agaagcgatt gcgtgatttg
     3601 gaaaacgggc aatgccttat cagtgattta tatggtcgtg tcggtgtgat acagttccac
     3661 cctgtatttg aagaactgct ccatgccttt gataccagac cacctgtgcg aaaagaggtg
     3721 taaatgtgaa accatcaata gtaaacagaa taaaatcaaa ctggacgctg aaacgtctag
     3781 gtaaagtggc aatgacagtg gctttcacac ttgtgattgc catttttctt ttagccatgc
     3841 tgggaacggt ggttcaagct gcgggcttgg tagatgatac ggtcaatgtg gcaaatgaat
     3901 acagccgata cccacttgaa aactatcaac tggattttta tgtggataat agctggggct
     3961 ggcttccgtg gaactggtcg gacgggattg gaaaacaggt catgtatgga ctatatgcca
     4021 ttaccaattt tatttggaca atcagtttgt atgtttccaa tgcgacaggt tacttagtac
     4081 aggaagccta ttccttagac ttcatttccg ctacagcaga ttccattggt aagaatatgc
     4141 agaccttagc tggtgtgagt gcaaacggat tttcaacaga gggtttctat gttggattcc
     4201 tcttactctt gattttggtt cttggggttt atgttgccta tacgggactg ataaagagag
     4261 aaaccacaaa ggcaattcat gccattatga attttgtgct ggtgtttatc ctatcggctt
     4321 cctttattgc ctacgctccc gactacatta aaaaaatcaa tgacttttca tcagacatca
     4381 gtaatgccag tttatcactt ggcacgaaga ttgtcatgcc ccattccgat agtcaaggca
     4441 aggacagcgt ggacttaatc agagatagcc tgttttccat acaggttcag caaccgtggc
     4501 tactgcttca atacaacagt tcagacattg aaagtatcgg tattgaccgt gtggaaagcc
     4561 tgctctccac cagcccagat tccaacaatg gcgaagacag agaaaaaatt gttgcggaag
     4621 aaattgaaga cagaagcaat accaatctaa ccattacaaa gaccattaac cgtttaggta
     4681 cagtcttctt cctatttgtc ttcaatattg ggatttccat atttgtattc ctattaacag
     4741 gaatcatgat tttctcgcag gtacttttta tcatctatgc tatgtttctg cctgtgagct
     4801 ttattttaag catgattcca tcatttgatg gtatgtcaaa acgagccata acaaagctct
     4861 ttaataccat tttgacacga gctggaatca cattgattat tacgacagca tttagtattt
     4921 caaccatgct ctatacctta tcggctggtt atccgttctt tttgattgct tttctacaga
     4981 ttgtgacctt tgcaggaatc tacttcaagc tgggcgattt aatgagtatg ttttctctac
     5041 agagtaacga ttctcaaagt gtgggaagtc gtgtgatgag aaaacctcgt atgcttatgc
     5101 acgctcacat gcaccgtcta cagcggaaac ttggacgttc catgactact ctaggggctg
     5161 ggtctgccat tgttacaggt aaaaaaggac agtcgggttc ggggagttct gcaaggacac
     5221 aagcagatca ctcccgacca gacggaaagg aaaaatcaac acttggaaaa cgtatcggtc
     5281 aaaccatcgg tacagtagct gataccaaag acagaatggt agacactgct agtggtttga
     5341 aagaacaggt taaagatttg ccgaccaatg caagatatgc agtatatcaa ggaaaatcca
     5401 aagtaaaaga gaatgtccgt gatttaacca gtagtatttc tcaaaccaaa gcggacagag
     5461 ccagtggacg caaggaacag caggaacaaa ggcgaaaaac cattgcgaag cgtcgctctg
     5521 aaatggaaca ggtcaaacag aaaaaacagc ctgcttcttc tgttcatgaa agaccgacta
     5581 caagacaaga acaatatcat gatgaacaga cctcaaaaca gtctaatatt cagacttcat
     5641 ataaggaatc tcaacaagcc aaacaagagc gtccagcagt taagtccgat ttttcaagtc
     5701 caaaagtgga acgccaaggc aataccgttc aagaaaaaac cgttcaaaag ccagcaactt
     5761 caaccactac agcagataga acttcacaac gtccaatcac aaaagaacgt ccgtctactg
     5821 ttcaaagagt accactacaa aatacaagaa gtagaccacc aatcaaaacc gccaccatta
     5881 agaaagtcgg taagaaacca tgaagttgaa aactttagtg attggtggtt ctggattatt
     5941 cttgatggtc ttctcactgc ttctgtttgt tgccatttta ttttcagatg aacaggacag
     6001 cggaatttcc aatattcatt atggaggtgt gaatgtttcc gcagaagtgc tggctcataa
     6061 gcctatggta gaaaaatatg ccaaagaata tggcgttgaa gaatatgtca acatacttct
     6121 tgcgattata caggtggaat cgggcggtac tgcggaagat gttatgcagt cctcggaatc
     6181 cctcggtctt ccacctaatt cattgagtac agaagaatcc attaagcaag gtgtgaagta
     6241 tttcagtgaa ttattagcca gtagcgaaag gctcagtgta gatttagaat cggttatcca
     6301 gtcctacaat tatggtggtg gtttcttagg gtatgtggct aatcgtggaa ataaatatac
     6361 ctttgaactg gctcaaagtt tctcaaaaga gtattcaggt ggcgaaaaag tgtcttaccc
     6421 caatcccata gccataccta tcaatggggg ctggcgatac aactatggca atatgtttta
     6481 tgtgcaactg gtaacgcagt atcttgtcac aacagagttt gatgatgata cggtacaagc
     6541 catcatggac gaagcactga aatatgaggg ctggcgatac gtttacggtg gagcttcccc
     6601 gactacttct tttgattgta gcggactgac acaatggacg tatggaaaag ctggaattaa
     6661 cttaccacga accgcacaac agcaatatga tgtgacccag catatcccac tatcggaagc
     6721 acaagctggc gatttggttt tctttcattc tacctataac gctggctctt atattactca
     6781 tgttgggata taccttggca ataaccgtat gtttcatgca ggcgacccaa tcggttatgc
     6841 cgacttaaca agcccctact ggcaacagca tttagtggga gcaggacgaa tcaaacaatg
     6901 agaaaggaag atttaatgat gaaatttaga aaaaatcaga ataaagaaaa acagatacca
     6961 aaggaaaaga aacctcgtgt ctactataag gtcaatcctc ataaaaaggt tgtgattgcc
     7021 ttgtgggtac ttttagggct tagtttcagc tttgcgatat tcaagcactt tacagctata
     7081 gatactcata ctattcacga aacaactatc atagaaaagg aatacgttga tactcatcat
     7141 gtagaaaatt ttgtagagaa ctttgcgaaa gtctactatt catgggagca atccgataag
     7201 tccattgata atcgaatgga aagtctaaaa ggctatctga cagatgaact tcaagctctc
     7261 aatgttgata cagtacgcaa agatattcct gtatcgtctt ctgtaagagg atttcagata
     7321 tggacggtag agccaactgg cgacaatgag tttaatgtaa cctacagtgt agaccagctc
     7381 attacagagg gagaaaatac aaagaccgtc cactctgctt atatagtgag tgtctatgta
     7441 gatggttctg gaaatatggt actggttaag aatccgacca ttaccaacat acctaagaaa
     7501 tcaagttata aaccaaaagc cattgaaagt gaggggacgg ttgattccat tacaaccaat
     7561 gaaatcaatg agtttttaac gacgttcttc aagctctatc ctacagcgac agccagtgaa
     7621 ctttcctact atgtgaatga cgggatatta aaaccaatcg gaaaagagta catctttcaa
     7681 gaactggtaa atcctattca caatcgtaag gataatcaag tcacggtatc gctgacagtg
     7741 gagtatatcg accagcagac caaagcaacg caggtatctc aatttgattt ggtacttgaa
     7801 aagaacggga gtaattggaa gattatagaa taacaaatat tggtacatta ttacagctat
     7861 tttgtaatca cgtactctct ttgataaaaa attggagatt cctttacaaa tatgctctta
     7921 cgtgctatta tttaagtatc tatttaaaag gagttaataa atatgcggca aggtattctt
     7981 aaataaactg tcaatttgat agtgggaaca aataattgga tgtccttttt taggagggct
     8041 tagttttttg tacccagttt aagaatacct ttatcatgtg attctaaagt atccggagaa
     8101 tatctgtatg ctttgtatgc ctatggttat gcataaaaat cccagtgata agagtattta
     8161 tcactgggat ttttatgccc ttttgggctt ttgaatggag gaaaatcaca tgaaaattat
     8221 taatattgga gttttagctc atgttgatgc gggaaaaact accttaacag aaagcttatt
     8281 atataacagt ggagcgatta cagaattagg aagcgtggac agaggtacaa cgaaaacgga
     8341 taatacgctt ttagaacgtc agagaggaat tacaattcag acggcgataa cctcttttca
     8401 gtggaaaaat actaagataa acatcataga cacgccagga catatggatt ttttagcaga
     8461 agtatatcgt tcattatcag tattagatgg ggcaattcta ctgatttctg caaaagatgg
     8521 cgtacaagca caaactcgta tattgtttca tgcacttagg aaaataggta ttcccacaat
     8581 cttttttatc aataagattg accaaaatgg aattgattta tcaacggttt atcaggatat
     8641 taaagagaaa ctttctgcgg aaattgtaat caaacagaag gtagaactgc atcctaatat
     8701 gcgtgtaatg aactttaccg aatctgaaca atgggatatg gtaatagaag gaaatgatta
     8761 ccttttggag aaatatacgt ctgggaaatt attggaagca ttagaactcg aacaagagga
     8821 aagcataaga tttcataatt gttccctgtt ccctgtttat cacggaagtg caaaaaacaa
     8881 tatagggatt gataacctta tagaagtgat tacgaataaa ttttattcat caacacatcg
     8941 aggtcagtct gaactttgcg gaaaagtttt caaaattgag tattcggaaa aaagacagcg
     9001 tcttgcatat atacgtcttt atagtggcgt actgcatttg cgagattcgg ttagaatatc
     9061 ggaaaaggaa aaaataaaaa ttacagaaat gtatacttca ataaatggtg aattatgtaa
     9121 aatcgataag gcttattccg gggaaattgt tattttgcag aatgagtttt tgaagttaaa
     9181 tagtgttctt ggagatacaa agctattgcc acagagagag agaattgaaa atcccctccc
     9241 tctgctgcaa acgactgttg aaccgagcaa acctcaacaa agggaaatgt tacttgatgc
     9301 acttttagaa atctccgaca gtgacccgct tctgcgatat tatgtggatt ctgcgacaca
     9361 tgaaatcata ctttctttct tagggaaagt acaaatggaa gtgacttgtg ctctgctgca
     9421 agaaaagtat catgtggaga tagaaataaa agagcctaca gtcatttata tggaaagacc
     9481 gttaaaaaaa gcagagtata ccattcacat cgaagttcca ccgaatcctt tctgggcttc
     9541 cattggtcta tctgtagcac cgcttccatt agggagcgga gtacagtatg agagctcggt
     9601 ttctcttgga tacttaaatc aatcgtttca aaatgcagtt atggagggga tacgctatgg
     9661 ctgtgaacaa ggattgtatg gttggaatgt gacggactgt aaaatctgtt ttaagtatgg
     9721 cttatactat agccctgtta gtaccccagc agattttcgg atgcttgctc ctattgtatt
     9781 ggaacaagtc ttaaaaaaag ctggaacaga attgttagag ccatatctta gttttaaaat
     9841 ttatgcgcca caggaatatc tttcacgagc atacaacgat gctcctaaat attgtgcgaa
     9901 catcgtagac actcaattga aaaataatga ggtcattctt agtggagaaa tccctgctcg
     9961 gtgtattcaa gaatatcgta gtgatttaac tttctttaca aatggacgta gtgtttgttt
    10021 aacagagtta aaagggtacc atgttactac cggtgaacct gtttgccagc cccgtcgtcc
    10081 aaatagtcgg atagataaag tacgatatat gttcaataaa ataacttagt gtattttatg
    10141 ttgttatata aatatggttt cttgttaaat aagatgaaat attttttaat aaagatttga
    10201 attaaagtgt aaaggaggag atagttatta taaactacaa gtggatattg tgtcctgtat
    10261 gtggaaataa aacacgatta aagataaggg aagatactga attaaaaaaa ttccccctct
    10321 attgtccgaa atgcagacaa gaaaatttaa ttgaaataaa gcagttcaaa gtaactgtga
    10381 ttacagagcc agacgcaaag acgcagagcc gataaaatga gattaataca atctcatttt
    10441 atcggctctt tccgttatgt atggattctt ttaattagtc ttcgatgttt cttgcttcgt
    10501 tgataccgct ggctaaagat tccattaagg atagttcttt gtctgtaaag ctatccatgt
    10561 atttctctat ctgtaatcgt cgggtgcttt ttaccaagtt attagcaggt aagaaaaatt
    10621 catcaacgga aacatgaagt aacgatacaa ggtcataaag aacttgtatg ctggggtgtt
    10681 gccctttatt ttcaatatta gttaagtacc gtgggtcaat ttcaatcaat gctcccactt
    10741 gttcacgagt taaacctcgt ttcaatcgag cttctttaat ggctaaacca aaggctctaa
    10801 aatcatattt atcttctttt ttacgcatag tagaccacct ctatacattt tattgttcct
    10861 actgaattaa aaacaggtat agaaaaacgt gttatatggt ttataggttt atatttaata
    10921 aaaagcacta ctaaacgcca ataaaaaaaa ccgttatatg gtagtgctat ttacgctgtt
    10981 aaaatattgt atattacttc caaatggcgg tttgttggag gtcaacgtcg ccatgaagta
    11041 catcatatac aataaatttc cttacattgg gttcttgtca aaaaaagtcg tctatctgca
    11101 atagataagt acgtccacca atgtggtttt ataaatcata tagatagaat aacagaagca
    11161 tgtaaacaga gaaataaatc tgtttatatg cttttttggc tattcagaac ttttttacaa
    11221 agtttattta tcagtaatgc aacaaatccc cctttcacat tgggactaag agtgaaagga
    11281 gataaacgag caaggctcac ttcctttcct agacagaaag ggggtgagaa acatgaaacc
    11341 atcttctttt cagaccacaa tagaaaatca gtttgactat atctgtaaac gtgctatgga
    11401 agacgagcga aagaattata tgctttatct ttcaaggatt gcaaagcgtg aggtgtcctt
    11461 ttcggatgtt ggcgattatc ttgttagcca gtttgcgaca acagataact attcaactga
    11521 ctttcagatt tttacactca atgggttatc agtaggcgtt gaaaatgatt tgttgagtga
    11581 agcattacgt gagttgccag acaagaaacg tgaaattcta ctgctgtttt actttatgga
    11641 catgagcgat tcagaaattg cagacctgtt gaaattgaac cgttctactg tctatcggca
    11701 tagaaccagt ggactagcct taattaaaaa gtttatggag gaatttgaag aatgaaaaca
    11761 caatatccta tgattccctt tcctctcatt gtaaaggcaa cagatggcga taccgaagcg
    11821 attaaccaga ttctacatca ttacagaggg tacataacga agcgttccct acgacttatg
    11881 aaagatgaat atggcaatca aagtatggtc gttgatgaag tcttacgtgg aagaatggaa
    11941 accagactga ttacaaagat tttgtcattt gaaattaagt aatatcctct ctcctttcgt
    12001 ggaagcgtgc taaaccattc cacgcttccc gaacagggag gtttgttatt ccaccaaagc
    12061 atattgagct ttcaatgtgt tttgataggc taacgagcca ttgttctttg aaaactgaat
    12121 aaaagtaatc gaatacgttt cgataagaaa agagccaacg gaactaaccg ccatgaccta
    12181 tcttataaag atagcgagcg attcatgtta gtgatccgag aagcaatctt tagcaggatt
    12241 gcctgcaacg acattcttat cgtgataatg atactcccat acagtcaata gtccgagcgt
    12301 gataaaaccg tcgcaggcaa tgagtatggc tacatgagaa ccatgcaggg gtggaactcc
    12361 cgtgagcttt gctaaagctg ttcgattgct ggtaaaacaa cttttatgaa atccaaataa
    12421 gtgatttgga aaggaggatt ttatgaagca gactgacatt cctatttggg aacgttatac
    12481 cctaaccatt gaagaagcgt caaaatattt tcgtattggc gaaaacaagc tacgacgctt
    12541 ggcagaggaa aataaaaatg caaattggct gattatgaat ggcaatcgta ttcagattaa
    12601 acgaaaacaa tttgaaaaaa ttatagatac attggacgca atctagcgtc gccaaagggt
    12661 cttgtatatg ataaaatagt attaagtcgt atcaaggctc tttccataaa ggaaaggagc
    12721 aaatgccatg tcagaaaaaa gacgtgacaa taaaggtcga atcttaaaga ctggagagag
    12781 ccaacgaaaa gacggaagat acttatacaa atatatagat tcatttggag aaccgcaatt
    12841 tgtttactcg tggaaacttg tggctacaga ccgagtacca gcaggaaagc gtgattgtat
    12901 ctcacttaga gagaaaatcg cagagttaca gaaagacatt catgatggta ttgatgttgt
    12961 aggaaagaaa atgacactct gccagcttta cgcaaaacag aacgctcaaa gaccaaaggt
    13021 tagaaaaaac actgaaactg gacgcaaata tcttatggat attttgaaga aagacaagtt
    13081 aggtgtaaga agtattgaca gtattaagcc atcagacgct aaagaatggg ctattagaat
    13141 gagtgaaaat ggttatgctt atcaaaccat caataactac aaacgttctt taaaggcttc
    13201 attctatatt gctatacaag atgattgtgt tcggaagaat ccatttgact ttcaactgaa
    13261 agcagttctt gatgatgata ctgtccctaa gaccgtacta acagaagaac aggaagaaaa
    13321 actgttagcc tttgcaaaag ctgataaaac ctacagcaaa aattatgatg aaattctgat
    13381 actcttaaaa acaggtcttc gtatttcaga gtttggtggt ttgacacttc cagatttaga
    13441 ttttgagaat cgtcttgtca atatagacca tcagctattg agagatactg aaattgggta
    13501 ctacattgaa acaccaaaga ccaaaagtgg cgaacgtcaa gttcctatgg ttgaagaagc
    13561 ctatcaagca tttaagcgag tgttagcgaa tcgaaagaat gataagcgtg ttgagattga
    13621 tggatatagt gatttcctct ttcttaatag aaagaactat ccaaaagtgg caagtgatta
    13681 caacggcatg atgaaaggtc ttgttaagaa atacaataag tataacgagg ataaattgcc
    13741 acacatcact ccacatagtt tgcgacatac attctgtacc aactatgcaa atgcaggaat
    13801 gaatccaaag gcattacagt acattatggg acatgctaat atagccatga cgctgaacta
    13861 ttacgcacat gcaacattcg attctgcaat ggcagaaatg aaacgcttga ataaagagaa
    13921 gcaacaggag cgtcttgttg cttagtagta caaatgaatt tactacttat ttaccacttc
    13981 tgacagctaa gacatgagga aatatgcaaa gaaacgtgaa gtatcttcct acagtaaaaa
    14041 tactcgaaag cacatagaat aaggctttac gagcatttaa gaaaatataa aaagataatt
    14101 agaaatttat actttgttta agtataaaaa atgaaaaaat acgagcagaa aactgtttta
    14161 tctgctatac ttggttcgtt gcaagttccc gaaaggatcc gcaggacgga gatgccttgt
    14221 aaccgaattt aactaggggg aatcattata atggtagaaa gacacttatt tacatcagaa
    14281 tctgtttctg aaggacatcc agataaaatt gctgaccaaa tcagtgatgc aatcttggat
    14341 gcaattttaa aacaagatcc aacagcacga gtagcgtgtg aaacgtctgt aacaactggt
    14401 cttgttttag tatttggaga aatatctacg acggcatatg tagatattca aaaagtcgta
    14461 cgggaaacaa taaaagaaat tggttataca cgtgcaaaat tcggatttga tggagataca
    14521 gcagctgtat tggttgcgat tgatgaacaa tctcctgata ttgctcaagg agttgatgaa
    14581 gcacttgaga tccgggatga agataaaaaa gacgtattag atgagattgg tgctggtgac
    14641 caaggtttaa tgtttgggtt tgctgtagat gaaacaccag aattgatgcc tttaccaatc
    14701 gctttgagtc atcgtctggt acgacgcttg gcagatttgc gtaaatcaaa tgaattaacg
    14761 tatttacgtc cagatgcaaa atctcaagta acggttgaat atgatgatca aggacaaccg
    14821 gaacgcgtag atacaatcgt tatttcaaca cagcatgatg atgcagtaga taatgaaaca
    14881 attcgtcatg atgtcatcga aaaagtagtg aaggaagtta ttccagctga attattagat
    14941 gatcaaacga aatattatat caatccgact ggccgatttg tcattggtgg tcctcaaggg
    15001 gatgccggat taacaggaag aaaaatcatt gttgatacgt atggcggtta tgctcgtcat
    15061 ggtggcggtg ctttttctgg taaagatgcg acaaaagttg accgttctgc cagctatgct
    15121 gcacgttata ttgctaaaaa cattgttgca gcagggcttg ctcgcaaagc agaagtacag
    15181 ctagcttatg cgattggtgt tgctcaacct gtttcgatct caatcaatac tttcggtact
    15241 ggaacggttc cggaagaaga actgattgct gcagtgagag aaaacttcga tcttcggcca
    15301 gcaggaatca tcgagatgct tgatttgcgt cgtccgattt acaaacaaac agctgcttac
    15361 ggtcattttg gtcgtacaga tgtagatttg ccttgggaac atacggacaa agtagatgcg
    15421 ttgaaagcaa gtttagcaaa ataagttata ttcagctgga acgatcgcca agtggtggtt
    15481 gttccagctt tttttatggc agttaacctc ttgaaaaaga tagtaattat ttatctattt
    15541 ttagatcctg tcataatgaa agggaggaat aagatgaaaa aagaaacaaa tgttactttg
    15601 gtcacagtga gtattttcat tgcaacgttc atgacggcta ttgaaggtac aatcgtaaca
    15661 accgctatgc caacgattgt cggttcatta catggaatgg aaatcatgaa ctgggtattt
    15721 tcgatttatt tgctgacaaa cgctatgctt actccgattt acggaaaact tgcggataaa
    15781 gtgggacgga aaccaatctt tatttttggg acattattgt ttattatcgg ttcgttattt
    15841 tgcggtttat ctcaaagcat gattgggttg attgctgctc gtgcgattca agggatgggt
    15901 gctggggcaa tgatgccagt agctttgacg atcatcggcg atctttattc tattgaaaag
    15961 cgagcaaaag ttttaggttt gaatagttca gcctggggga ttgccagtgt ttttggaccg
    16021 cttgcgggag gattcatcgt tgaaacgatc agctggcact ggatcttttt tatcaatgtg
    16081 ccgatcggaa ttctattaat tattttgatt tggctatatt taaatgaacc aaaaatcata
    16141 catgagtcta aaccaatgga tatttttggt agttttagtt tgatggccat gcttgtctca
    16201 ttgctgttag ggttccaatt attaggagac gaaggaatga gtccgcttgt ttctgctttg
    16261 ctgctaggta gtatcgtaat gttaggtatt tttgtttttg ccgaaaaaag agctaaagat
    16321 cctgtcatca tgatgcattt attcaaaaat ccactatttg ttgtggtcaa cttggctgca
    16381 gcattggcta gtggtttttt gatgggaatc gatgtttata tccctatgtg gatgcaaggt
    16441 gtattagggc tgaatgcagc aattggtggg ctggtattag caccattatc actagtctgg
    16501 atggtcggtt ctttccttgc aagcaagtgg atgactcaaa tgaaaactca ttgggtcttg
    16561 agaattggac tactaatcgc agctattggg ggcgcttggt tgtatcttat gcctttcaga
    16621 agtaactatt tatggttttt tgctatatca acggtcatcg gtataggctt aggtgtgacc
    16681 atgactacct cgactgtcag tgcacaaaat agtgtatctc gtgaccagct tggtgtagca
    16741 acttctttta atacgttagt tcgaacaatt ggtcaaacag tcatggtttc tatttttggt
    16801 ttattgataa atggggtaac taaacgagaa cttgcagcag caaatttaac aaatgatgca
    16861 gatatcatga ataaactggt gaatccacaa acggctaaat atattgatgc ggatattttg
    16921 ttaccattaa gaaaaattct ttatgatggg ttacattccg tttatctagt tggcttgtta
    16981 ctcgtgatca ttgctttggt cttaacgctt ttcgttcatg aaaaaagtgg taaaataaaa
    17041 cagtagtttc ggttaagata tgtacgtagc cgaatcattc aaatttaaag ttattcaaaa
    17101 ataacttctt actaaggaag gcgaaaatat ggcatttatt caagcaaata tttattcgaa
    17161 tgtgttagaa atggaagtca atctaaatgt gatactaccg caaacaacaa aaaaggtgat
    17221 tggcaccagt tcagagcaag agacaacgga tatacctgtt ttatatttac ttcatggaat
    17281 gggtggcaat catagtgtat gggaaagacg tacgtcgatt gaacgttatg tagcaaacta
    17341 cggattagct gtcatcatgc catctactga tcttggctgg tacacagata cagtttatga
    17401 catgaagtat tggacattca ttgcagaaga gctacctgag atttgtcatg aattattccc
    17461 gcaattaaca agaaaaagag aaaaaacata tgccgctgga ttatcgatgg gcggatatgg
    17521 cgcgttaaaa ctaggccttg caaaatcaga aaatttcgca gcagtaatct ctctttcagg
    17581 cgctgtttct gtaggaaatc gaatggatga tcttttgatg gttcgtaaag catctttttg
    17641 ggaagggatc tttggaccat tggatcaaat cgaaggttca aaaaatgatc cgcaatactt
    17701 attgaaagaa ctagtaaaaa gcggaaaacc agttccaaga ttttatatgg cttgtgggga
    17761 atctgatttt ctttatcagg caaatcagga aatggtatct gctatgcagg aacaaggctt
    17821 ggcggtcacc tttgaacaag gacctggcga tcataactgg atcttctggg accaatggat
    17881 tcaacgtgca ttggcgtggc taatggaaga aaaataaaaa aagagtctta aaaagatagc
    17941 tcctatagag atcacaaaca tagtgatctc tataggagct tttttactgc tcgttttctc
    18001 ttcttttatt ttgttggcat aagccttcaa tataggtttg tgcactcgtt agaaagagtg
    18061 ctttttcatt caattctgca tgggactgca tactttcttt aaatccctct aattgatttt
    18121 caactacata attacgcata aatagaactg tttctttcaa aaattcattt ccgtccataa
    18181 ttttttgtcg aagctgctgt tcatgctgct gatccattaa ctgtccaatc aataaattgt
    18241 ggagagaggc aatggcctga tgactttggg tgactgaaaa tccttcacga acaagtaatt
    18301 ggatcatttg ctccaaatgt tctaatcgac tcggaaaagc gggcacagta ttgatttcta
    18361 attctgcccc acaagggaaa cgtgtataaa ggtcatagta attttccata tactgcagca
    18421 actgttcatt ccaaggcaaa gttggatctg gaagcgctaa ttcttcttcc attgtttcag
    18481 ccattttttg caagagctgt tgtttgtttt tgaaatacca atataaagca ggtgcttgaa
    18541 catgaattct gtttgcgatg tttcgcatgg aaagctgcga aagagcttgt gtttcagcca
    18601 ggatatcaaa ggcggcctga atgatgattg cttgagaaag ctttatttcc attttatcaa
    18661 cctcgtgtat tgcattatct ttttaaacat ggtaaattgt tagtcggtct aattttacag
    18721 tgttaaatta gtcctgtcaa tttaaacaaa ggggtgtaat caacgaatga aattaatctt
    18781 acgacatgcg aaaaaatata aagtagctgt ttttatttcc ttgctgtccg tagcagtcat
    18841 ggttgcagca gcattatggc aacctaagtt actacagcaa gtattggaag ctattattac
    18901 agaagataat gatgaaatga aaacaattgg tatttacctg atcagtctgg ctttgctagg
    18961 attagccgca ggtgtaacga acacgatttt ctctgcaaaa gtagctcaag gcgtaagtgc
    19021 agatatccga gaagaagcat ttcgaaagat ccagacattt tcatttggaa atatcgaaca
    19081 gttctctgct ggaaatcttg ttgttcgtct aacaaatgat atcacgcaaa tccaaaattt
    19141 agtgatgatt tctttgcaat cactttttcg aattccattc ttatttattg gtgccttcat
    19201 tttagctatg atcacgatgc cgcaattatg gtggatcatc gtagcgctta tcgttacggt
    19261 atttttgatt acggcacttt catttacaag gatgggcaag cacttcatga tcattcaaaa
    19321 actgattgat cgtgtgaata gcattgcaaa agaaaactta ctagggattc gtgtagtgaa
    19381 atcttttgta caagaagaaa accaattgaa gtcattcagc aaagtaagtg aggacttaac
    19441 aaaacacaac atcatagtcg gtacattatt ttctgtgatg atcccgtcct tcatgctggc
    19501 tgccaatttg gctgtggttg gggcgatctt ttttgtgagc gatcttgtta aagatgatcc
    19561 tacgttaatt ggtggaattg cttcattcat gaactacttg atgcagatta tgatggcaat
    19621 cattattggc ggaatgatga tgatgatgac ttcaagagca gccgtatcgc tgaagcggat
    19681 tgcggaaatt ttagatgctg aaccagatct tacttattta gacgttccag aacaagagtt
    19741 gacgggttct gtcacttttg accatgtttc ttttcgttat cctggtgagg atacagatac
    19801 gcttaaagat atcagctttt ctatcaaacc tggagaaatg gttggtatcg tcggggcgac
    19861 tggtgccggg aagtcaacac tagcacaatt gatccctcgt ctatttgatc cgacagaagg
    19921 caaagttgaa gtaggtggtg tagatcttcg tcaagtaaat gaaaagagtt taagacaaac
    19981 ggtttccttt gttttgcaaa aagcaatttt attctcagga acgattgctc aaaacttgcg
    20041 ccaagggaaa aagaatgcaa cagaaaaaga gatggaacat gcttcttcta ttgctcaagc
    20101 aaaagaattc atcgaaaagt tatctgatcg ttacgaagca ccaatagaag aacgtagcag
    20161 taacttttct ggtggtcaaa agcaacgttt atccattact cgtggcgtta tcggtaatcc
    20221 aaagatcttg atcctagatg acagtacgag tgcactggat gctcgctctg aaaagctggt
    20281 ccgagaagca ctcgatcgag atttgaaggg aacaacgacg attgtcatcg cacaaaaaat
    20341 tgcttctgtt gtcaaagcag accgcatctt agtattggat gaaggcagat tagtcggcga
    20401 aggaacccat gaggaattgg tagctggaaa ccgtgtctat caggaaatct ttgaaactca
    20461 aaaaggaacg gaggagtaag tatgactgat ctaataaaag caagtaaatt tttctatcac
    20521 tatttgaagc ggtacaaact ctcctttttc tttatcttta tcacagtgat cattgctacc
    20581 tatctacaag taaaggcacc tcaatacatc ggggaagctt ttcaagaatt agctaattac
    20641 gtaggaggct tgatgcaagg cgtagacgat aaaagcaaat ttgtttctgt aatatggaaa
    20701 ctcttgctgt tttatgtact agctagtgca gccaacttta tctatagtat tttgttcaca
    20761 caagtagtag ggaagtcaac gaaccgaatg cgtatcggtc tattcaacaa attggaaaaa
    20821 ttgacgatcc gtttctttga ttctcatcaa gacggtgaaa ttttaagtcg ttttaccagt
    20881 gacttagata atattcaaaa tagtttgaac caagctttgc ttcaagtcat cacgaatgct
    20941 gttttacttg tcgggatctt gatcatgatg ttccgccaaa atgtagagtt agcttgggct
    21001 acaattgctt ccactccagt agccgttttg atagctgtct tgattatccg caaagcacgg
    21061 aaatatgtgg atcttcagca agatgaagtg gggaaactaa atggttatat ggatgaaaaa
    21121 atcagcggac aacgtgtcat catcacaaat ggcttacaag aagaaacgat tgaaggattc
    21181 ttagagcata atcaaagtgt tcgcgaagca accttcaaag gacaagctta ttctggtcta
    21241 ctatttccga tgatgcaagg aatgtcactg gtcaatacag cgatagttat ctttttcggc
    21301 ggctggttag cattaaatgg tgatttggaa cgttcggtgg cattaggctt agttgtgaca
    21361 ttcgtccagt attcacaaca atattaccaa ccactgatgc agatttcatc tggatacagc
    21421 atgatccaat tagcgattac aggggcaaga cgattgaatg aaatatttga tgaaaaagat
    21481 gaagtcaaac cagaaaacgg taaagcattt gatggtgttg aaaaaggtct tgcgttgcag
    21541 cacgtagatt ttggttattc tccagaaaaa ctagtcttga aagatgtctc gatcaatgtg
    21601 gacaaaggag aaatggttgc tcttgttggt ccaacaggat cggggaaaac gacgatcatg
    21661 aatctgctaa accgttttta cgatgtcaat gatggttcag tagtcatcga tggaatagat
    21721 atccgagatt atgatcttga tgcattacgt agacatgtag gaatcgtttt gcaagaatct
    21781 gtattgttct ccggaacgat caaagacaat atcacattcg gcaaaccgga cgcttcagat
    21841 gaagaagtca tcaatgcagc aaaacaagcg aatattcatg acttcatcat gacgttagaa
    21901 aaaggttatg atacagagat atccgaagaa aataacttat tcagtacagg tcaaaagcag
    21961 ttgatcagta ttgctcgaac gatcatcaca aatccatctt tattgatttt ggatgaagca
    22021 acaagtaatg tagacacggt aacagaagca aggatccaaa aagcaatgga tgaagcaatc
    22081 aaaggaagaa ccagctttgt gattgctcac cggctgaaaa caatcttgaa tgcagataga
    22141 atcgttgtct tgcgtgatgg ggaagtcatt gaagaaggca gtcatcacga gttattagca
    22201 gaaaatggat tttatgcgga actttatcat aatcaatttg tatttgaata aagaggttgt
    22261 gaaaaagctg tcctgcatca agtaataaga acagccaatc aaaaacagct tctcatgttt
    22321 ttgatttggt tggacttatt accgcagata taagcttttg agcaccgtga ataaagaggt
    22381 tatgaaatca acgctctaac ctgagtatta gagaaaaaaa cgcaaaacat atcatttatg
    22441 ttttgcgttt tttatttatc tttttttctc aatacaatat aaaataggcg gctggttctt
    22501 ttggttgata aaccgataat tcagcacatt atatgtttcc tgtggcagtt tggaacaaaa
    22561 agaatcaacc atatccagtt ctttttctcc accttcatga ccatagtaga cgacaaggat
    22621 caatcgtccg cgaggcacaa gtcgtttcaa tatttcttcc atagctgtgc gtgtagtctc
    22681 tggcatagtg atgattgctt tatcactttt tgggagatac cctagattga aaatccctgc
    22741 tttgagattt tgttgttcag ctatcacttc tcctaacgtt tcgtggcctt gtagaaacaa
    22801 tgagacacgt tcttctaact gacgctgttc tagcctttca cgagtagcat cgattgcttg
    22861 ttgctggata tcaaaactat agacatgacc agtttttccg atgtgttctg ctagaaaaac
    22921 cgtatcgtgg ccattgccca tcgttgcatc tacgacgtga tcccctggtt gcaagatttc
    22981 ttgcagtaat gtatggctga aatgcaaagc agtttgcaac atcagacgct cacctttttc
    23041 cgtacatcat attttccttg gaagctatct ctgcgaagaa gttcttcatc aattgcattc
    23101 aagacttccc attttttcaa gctccacatt ggtccaatca aggaatccca cggcgcatcc
    23161 cctgtcaaac gatggatgat gatctctttt ggtatcattt ccagctggtc gcaaatgaca
    23221 ttgacatagt caggacggct cattaattga aggcgacctt catgatagtc ccgcaacatt
    23281 ctcgttttgc gcatcagatg catcaaatgg agcttgattc cttggatatc tgaatctaaa
    23341 atggtgcgtc tgacattttc tttcatcatt tctaaacttt cgcctggtaa tccgttgatc
    23401 aaatgcgtac aaacacggat attatgtttg cgtaatttag ccacgccatc taaataagtt
    23461 tgataatcat gtgctcggtt gatcagtttt gaagtttctt caaaagttgt ttgcaatcca
    23521 agttctaccc ataaatacat ccgctcgttc agttcagcaa ggtaatcaac tacttcatct
    23581 ggcagacaat ccggtcgtgt accgactgat aatcctacga cacctggtaa attgactact
    23641 tgctcaaatc gttctttgat tatttcaact ggcgcatggg tgtttgtaaa attttggaaa
    23701 taaacgatgt attgttggac atgaggccat ttttgatgca tcatgtcgat ttctttctgg
    23761 aattggattg gaagagggtc ttcaggtgca acgatcatgt ctcccgaacc agatacactg
    23821 caaaaagtac aaccgccatg ggcaacagtc ccatctcgat tcggacagtc aaatcctcca
    23881 tcgatcggca ccttgaaaat tttcccgcca aactcatttc gtaaagcgta attccaagaa
    23941 tgatatcttt tatttccttc tgaataagga aaagtcatta aaagtccttc tttctgtaag
    24001 agttatctat ttgttttctt ttttctctat acactggata agtcaggcac agccaagaaa
    24061 gactgagtaa gtagccgccg atgatatcag taggaaaatg aacgcccaga taaatgcggc
    24121 ttatcccgac acttactata ataaacatca tcagcaattg aagcaatgtg cgtaaggttc
    24181 ttttttgaac aaaagctgga agcagaaata gtaaagaacc gtaaagaatc atactgcctg
    24241 ctgcatgtcc actagggaaa ctgtaacttg tttcaactac taagtgcgcc aatgaaggac
    24301 gctctcgcat gaaaaatagt ttgatcaccg ggttgatgat tccagcaatt acaataaatc
    24361 cagaaacgaa ccaaaatgtt tctgcccttt ttttcttata ccacatccat aaagccgcac
    24421 aagcaaataa aatgatgacg gtaagaggat taccgaattt agtcataaag agttggtagc
    24481 tgttcagatc aggataagaa gctctgacaa tgcctgtaaa ccactgatcg aaaccagaaa
    24541 gccacgacag atggaacttt acgatccagc ccaaaatgaa aaacaggaca agaaagaagc
    24601 taccagccac ctgaaatgat gttttatatt tcatacaatt cctcctttga agcaatgact
    24661 tattatagca tttttggtcc agcgaaaaaa acggtaaaga gataaaacca atgtatgatt
    24721 cctctttgaa taaccaatat tcttataaaa aaaataactg taatcggaaa gacatttttt
    24781 ggtaatgcaa atgaaatgtt agggaaataa aatcagtgtt tttcgaaatc cttttaaaca
    24841 agaacgtaga cgtaggaaga acttgaaaat gaacagaagt tgttcattac ggtaaattac
    24901 aatatgatta caaaaaacaa caaagctctt aaataacttt taataaatat taagagaagt
    24961 tataattatt aataatagat aaattgaagt tggaggatag aagatggaaa acattgcaag
    25021 aaaagaacgg agacgtttag aacagaccaa acgttttcga aaagcaaaac gaggggcagc
    25081 aatcgtggga actgcgatgg taggctgttc tgtcgctgcc ccattagtac agccggttcc
    25141 tgttcaagcg gatgaaacac ctgttcagtt cggcgcaaga atcaatacag cggcatttat
    25201 cacagaaatt gctacttatg ctcaaccaat cgctcaagcc aacgatctat atgcatcagt
    25261 gatgatcgca caagcagttg tagaaagcgg ttggggcagt agtgcgttat ctcaagcacc
    25321 ttattataat ctttttggga taaaaggcag ctatcaagga caaaccgtct acatggatac
    25381 gcttgaattt ttaaataatc aatgggtaaa taaaaaggag cctttccgac aatatccttc
    25441 ttttgctgaa tctttcaatg acaatgccta tgtacttaga aatacttcat ttggcaacgg
    25501 ttattactat gccggtactt ggaagagcaa cacgaaatcc tatacagatg cgacagcttg
    25561 tttgacaggg cgttatgcga ctgatcctgg ttacgcaggc aaattaaata atatcatcgc
    25621 aacttacgga ttgacccaat atgatacacc agctagcgga aacgcaggcg gtggagcgac
    25681 tacaggtggc aataatactg gaagtgcagg tagtactggc ggttcaagca attctggtaa
    25741 tacaaactca ggttcagcaa cttcgaccac ttatactgtc caatctggtg attctgtttg
    25801 gggaatctca aataaattcg gtatcacaat ggatcaattg atccaatgga acaacatcca
    25861 aaacaatttc atttatccag gacaaaaact gacaatcaaa ggtagccagg aaaatggctc
    25921 ttcgacgaat aattccggta acaataccaa ttcttcagga aatgctggta catcaaacgg
    25981 aggacaaaca actggtgcga aatacactgt tcaatctggt gattctgttt ggaagatctc
    26041 aaatgatcac ggaattacga tggctcaatt gattgaatgg aacaatatca agaacaattt
    26101 cgtttatcca ggacaacagc taatcgtatc aaatggcggt tcttctaatg ctggagcaaa
    26161 tactggctca aatactggga atacaagtgg ctctagttcg tccagctcaa gttcttctaa
    26221 tacagcttca ggaacgaaat atacagttaa agccggagac tctgtttgga gcgtctcaaa
    26281 taaatacgga attacgatgg ctcagctaat ccaatggaac aatatccaaa ataactttat
    26341 ctacccagga caacaactga ctgtttcaaa cagtggatca acaaacagca cgtcaggtaa
    26401 tacaggttcg tcaaccaata caaataacag cagttcagtt aatactggca gcagttcgtc
    26461 tcaaggcact tataccgtga aagcaggtga atctgtttgg agcgtggcaa ataaaaacgg
    26521 catcacgatg gatcagttaa tcgaatggaa taatatcaaa aacaacttca tttatccagg
    26581 acagcaattg atcgttaaag gtggaacttc ggcaaataca aatacaggtt caactacttc
    26641 tgcagcgaaa ccaaatacac cgaatacgtc tgctacgaca agtacatcat ccactggtaa
    26701 tacgatgtat accgtgaaag cgggcgagtc agtttggagc gtagcgaaca aacatcatat
    26761 cacgatggat cagttaatcg aatggaataa tatcaaaaat aatttcatct atccaggaca
    26821 gcaagtgatt gtgaagaaag gttcatctca atcaacaaac caacaatcag ttactggttc
    26881 gaaaacctat actgtgaaat ctggagaatc tgtttggagt gttgctgaca gtcatggaat
    26941 tacaatggct caactaatcg aatggaacaa tattaagaac aactttattt atccaggtca
    27001 aacgttgatt gtagctaaat aaaatagctg ttcgaagaaa taacgattga attccacaaa
    27061 aatatttgtt actataaggc tacttaaata tgacaacact tgaaaaggaa gtagtaaaaa
    27121 gactgaagtt tcagagagcg catggctggt gagaatgtgc acggatgctt ttgaactcgc
    27181 ctttgagttg cccttgctga atacccgagt aagcaagcgg cggtgacggc cgttacaacg
    27241 ttcgaggcct tttcactaag gtaaaattag gtggtaccgc gtagattacg tcctataaaa
    27301 agagcaatct ttttatagga tttttttatt tcttttgtga agtttgagaa aacaaagcaa
    27361 aaggaaataa aaataaacag attctgccgg ttttttcgtt atatttataa tagaaacaag
    27421 tgttttcaat agaacaggag gacagcaaat gagttacaat cataaagaaa ttgagaaaaa
    27481 atggcaaaaa tactgggcaa aaacgaatac tttcaacacc catgatgatc ctgaaaagcc
    27541 aaaattttac gcactggata tgtttcccta tccatccggt caagggctac atgtagggca
    27601 tcctgaaggt tatacggcaa cggatatcct ttcacgtgtg aaaagaagtc aaggatacaa
    27661 cgtgctgcat ccaatggggt gggatgcatt cggtctgcct gctgaacaat atgcgctaga
    27721 tacaggaaac gatccagctg agtttaccca aaaaaatatc gaaacattcc gacgccaaat
    27781 caattcttta ggatttagtt atgactggaa tcgcgaagtg aatacaactg atccggagta
    27841 ttataaatgg acacaatgga tctttacgaa gctttatgaa aaaggtctag cttatgaagc
    27901 agaagtagcg gtaaactggg tacctgaatt aggaacagtt atttcaaatg aagaagtgat
    27961 cgatgggaaa agtgaacgtg gtggctatga tgtagtcaga aaaccaatgc gccaatggat
    28021 gctgaaaatc actgcttatg ctgatcgctt attggatgat ctagaattag ttgattggcc
    28081 agaaagcatt aaagaaatgc aaagaaattg gatcggtcgt tcagtaggag caaatattga
    28141 atttaaagtg gctggtacgg ataaatccta taccgtattt acgacacgac cagatactct
    28201 attcggtgca acttactcgg ttcttgcacc tgaactagat cttgttagag aaattacgac
    28261 ccctgaacaa aaagctgctg tagaagctta tatcgaagag acagctaaaa aatcagatct
    28321 aaagagaacg gatcttgcaa aagaaaaaac aggagtattt actggtgctt atgcaatcaa
    28381 tccagttaat ggcaaggaaa tcccaatctg gatcgccgat tatgtattat cttcatacgg
    28441 cacaggagcc atcatggctg ttccagcaca tgatgaacgt gactttgaat tcgctcaaac
    28501 tttcggacta gaaattcttc cagttatcga aggtggagat gttgaaaaag ctgcttacac
    28561 agaagatggt acgcacatca actctgaatt tctagacggc atgaacaaac aagaagcaat
    28621 cgataaaatg aatgaatggc tagaagaaaa tggcgtaggg aaaaaagaag tcagctatcg
    28681 cttacgtgac tggctattct cccgtcaacg ttactggggt gaaccaatcc caatcatcca
    28741 ttgggaggac ggaacagtca cagctgtccc agaagaagag ctaccattac ggttgcctaa
    28801 gacaaaaaac atcaagccaa gcggtactgg agaatctcca ttagcaaata tcgaggagtg
    28861 ggtcaatgtc gttgatcctg taacaggtaa aaaaggccgt cgcgaaacga atacaatgcc
    28921 acaatgggca ggaagctcat ggtattacct gcgttatatc gaccctcata acaaaaaaga
    28981 actagcagat tatgaaaagt tgaagcgttg gctaccagtt gacatctaca ttggtggagc
    29041 agaacatgcg gtacttcatt tactatatgc acgattctgg cataaattct tatacgatat
    29101 cggtgttgtt cctacaaaag aaccattcca aaaactatac aatcaaggaa tgatcttagg
    29161 cgaaaacaac gaaaaaatgt caaaatctcg tggtaatgta gtcaatcctg atgatgtggt
    29221 cgaaacttac ggtgcagata cactgcgcat gtacgaaatg ttcatggggc cattagatgc
    29281 ttcgattgct tggagcgaaa atggcttaga aggaagccgt aaattcttgg atcgtgtatg
    29341 gcgtttgatc gttgatgaga acaataaaat gcgtgaccgt atcactacat tgaatgatgg
    29401 caagcttgat aaagtgtatc atcaaacagt gaaaaaagtg acagaagact atgaaaatct
    29461 tcatttcaat acagcaatct cccaattgat ggtctttatc aatgaagcct ataaagtgga
    29521 cgctctgcct tatgaatata tcgaaggatt tgttcaacta ctcgcaccga ttgctcctca
    29581 catgggtgaa gaactatggg caatccttgg aaatgatggt ggtatttctt acgcaccatg
    29641 gccaacatac gatgaagcag cacttgttga agacgaagta gaagttgttt tccaagtaaa
    29701 cggtaaagtt cgtgcgaaaa gcaatgttcc ccgagactta ggaaaagatg agctagaaaa
    29761 agcagcatta gccaatgaaa tagtgcaaga atatattgaa ggcaaaacag tcagaaaagt
    29821 tattgcggta ccaaacaagt tagtcaatat cgttgctaat taattggctc tttgtcaata
    29881 aggactgatg agttgtgcaa aatcaaatct gggccagaat gaacttcatt ctgtctcaga
    29941 ttttttgtta tttcaaattg attaattgat tgatcaaaaa ggttttgatt ttcatgttct
    30001 caaacacgtt caatgtcttt ttcttctgaa tggtcttgta agagatctct gtaatcatca
    30061 aatttttgtc tattaatctt agtatttttt gatgtataaa ctacctgaaa ttgagagtac
    30121 ataccaaatt cataaatttt ttattagtgg gactagtgat tgtatggatt ttgacgcata
    30181 atgaatgaag tatgagaaaa ggagagacaa atggatcaag aactatttat tatcgaagta
    30241 ttatcagcta aacaaaaaat tatcgagaaa gcgaaaaaaa gagcgaaaag aataatgttc
    30301 aagcttttaa gcttagtatt tttctctggt ttgctttttt tcggagctgt atcgttccta
    30361 tatcgccata tgagtgcagt agtccgttca gctgaaggga tgcaaaaatt aaataatttg
    30421 tatcactttt cgtggggagt tggcggaata acaattgttg tgcttattgt ttttcttcta
    30481 cttatttggc tccgttacca tcaattgtcg cgtcatttcg atcaatggct tagtcaaaga
    30541 gcacaacagt ttttacataa taaaccaact tctcaagatg atgactatct ttattttgag
    30601 aagacttcga cgagtcaagc ttttcggata caaaaaagtg attgccagtt attgctgaga
    30661 tcacttgatg atttacctat ctacttaggc gaaagcaaat caaaattcgg aatgaacaca
    30721 ttccatattt ttttactaga aaacgaaccc agatgggaaa aaagccagtc ttcgcctggt
    30781 ggatacctga caactaagat gagtacatta gtcactggtt ttttcctcat tcttttagct
    30841 ggaacaatct attatgggag atacactcag ccaaaaatgt cttctcatat aaatgctgct
    30901 tctcacatga caatgaactc aactaacgat acgcatatac aaaagacaaa tgaagggttg
    30961 ttagctgatc ctaagcaaaa ggtaaatttg acaacacaaa agataaatga tctcaaactt
    31021 gatacagaga cgcactctct ctatatgaca acagatagtg gtgctaattg ggtatttgtg
    31081 ccgattgatt cgcaatggtt gcgttttggc gaatacaccc tgacaacggg gctgattcct
    31141 gaaggttatt ggatggacaa cacatatgat atttccgccg atttctcatg gtttatctat
    31201 tcttctgggg atgatgtacg tctgctgact tcaagagata atggtaaaac atggcaaacg
    31261 tctattatca cccaatcagt tcagccgata cgttatcgaa aagcggtatt ttatggcaac
    31321 gatggtctat ttatctgtac atcagccagt gggatgtctg cagaaacttt gtacatttac
    31381 actactatgg atggcggaat cacttggata aaaagtggaa gtacaatgat caatcagcca
    31441 gtacaaaatg tcagcttcgt tacaacttct ttaggttttg tttcgacacg tgaaagtttg
    31501 ttttatacaa acaacggagg acgctcattc aaagaatcag ttctgtcgat tccggaaaac
    31561 tatcagacag gggggataga tctttttcaa tcaccaaatg aagttactca aataagcgcg
    31621 aatacgttag agacaaaatt ttatttgttg aaaaaaggac caatcgatgc agggaaaatg
    31681 tttgcctgcc tcttccgttc aactgataac ggggaaacat ggcaattcgt tcagcaacta
    31741 tcgcaagtag aacaaggaga ttaaagaaga gagattgtga gcctgacgtt cagcaccgag
    31801 tcacaagaaa caaattcaaa aaacagcttc tcatatttgt tgaatagtgt aactcgtgat
    31861 tcggagttga caagagcaac aagaagcgat tttgaagtat agcttctcgt attttacaag
    31921 atcgtgtctt attgccgata ggttgtctct tgaacaccgt ttattcgtaa aaagggattg
    31981 tgacaagtct tttgtcacta cttaccgaac gaaactgaag gagctatcca aaaagtatca
    32041 ttagtattat tctttgtgtt tctagtggca ccactagtac atttaaaaaa gctatcgatc
    32101 atggactaat catacatgat cgatagcttt ttagataatg tttgttacgc tatctgaaat
    32161 tgactattat aaagactggc ataaagcgtt ggtgattgga gtagttcaga atgtgttcct
    32221 ttttcgacga tatcgccatt tttcattaca aggatcatgt ctgcattttc aatcgttgac
    32281 aaacggtgtg caatcacaaa acttgtccta tcttttgtca cagcttccat tgcttgctga
    32341 atcaatgctt ctgttcgtgt atctacgcta gaagttgctt catctaaaat aacgacagga
    32401 ggattcgcta gaatgactcg agcaattgtc aataattgtt gctgtccttg agataacgtg
    32461 ccgttttcgc tagaaatgat cgtatcatat ccgtctggca gtgttcgaat aaagtgatca
    32521 cattgtgcga tttcagccgc ttcgataatt tgttctcttg tggcatccat tttcccgtag
    32581 gcgatattat cagctaccgt tccttcaaac agccaggtat tttgtaaaac catcccaaaa
    32641 gaacgacgta gttctccacg tgaaagcttg gtaatatcaa gaccgtcgaa ttcgatcttt
    32701 cctttattca gttcataaaa acgcatcagc agattgacta aagtcgtttt tcctgcacca
    32761 gttggaccaa cgatcgctac cgtttgtttt ggctttactg aaaaatcgac ttgattcatc
    32821 aatattttat ctgatgtgta accaaactgt acatttttga aagctatttt tcctttcggt
    32881 tgttctaaaa gtcttgcatc tggaaggtct ggaatttcat ctgtttcatc taatatctca
    32941 aatatcctat cgattgctgc cattgcggat tggatcgagt tgatcacata agaagcggta
    33001 gaaattggtt cagaaatctg attgatgtac tgaagataag cttgtaagaa gccgatcgtc
    33061 acaccacctg atagaacaag catagcaccg aataccgcac ttatgatgaa ggcgagttga
    33121 ttaatgaaac gaatggccgg atagatagca aagttcataa attgagcacg tttaaaagcg
    33181 ttgtattgct ttttatttac ttcgtgtata gcagcttctg catgagcttg ctgattgaat
    33241 gttttgacca ctagattacc agctaagatt tcttccattc gattatttaa aacacccagt
    33301 tcatactgat tctgttcaga aatctgtttg tttttgttcg caatcttagt tgtaacaatt
    33361 gaactgccaa cgatcagcaa taagacgagc aaagtaagct tgctttcgat ataaaacagc
    33421 atcagaccag cagcagctat tgttacgaca gaagtaaaaa attgattgat acctgtcaat
    33481 aacacttgag aaagttgatt gagaccggta gttgtccgac taatgatgtc acctacttga
    33541 tgattgtcaa aaaacgacat cggtaatgtt ttgaattttt ttgtgatttc ttttcgcacc
    33601 ctcaatgtga tcttttcgct taacgctgcc attgtccgtt cctgaataaa tgaagtgatg
    33661 ctgcttaaga ctgaacagcc gatcagcaat aagacaggga acaacaatgc ttgtttgata
    33721 tcactgaaag aaagctgtcc aatacctgtt tttcttattt ctgataagag atcatcgatc
    33781 ccgattccca tgatcaaggg catggctacg actaataggt tcccgaataa actgtataga
    33841 aacaatccgt aaaaatattt atgttcaggt ttgatcattt tccaaaaacg tatcaaagca
    33901 cgcgtgttca acgttttttt cttttccatc gtatcccttc tttctatatt ccttgtgatt
    33961 ttgcaaactc ctgataagtt tggcaattag acagtagttc ttcatgagta ccttgtccaa
    34021 cgatttttcc ttcatctaaa acaatgatgt tatctgcttg ttggattgta ctgaggcgtt
    34081 gagcaacaat cacgagagtt ttctccgaca tgtgtttatg aagggctgct cttaatgctg
    34141 catctgtttt atagtctaaa gcggagaaac tatcatcgaa tacatagatc tctgctggtt
    34201 tgatcaacgc tcgagcaata catatccgct gtttctggcc ccctgaataa ttagaaccgc
    34261 cttgagcaac aaagctgtcc aatccgtcag gaagggtgtc cactagttct tctaattgag
    34321 cgatcttgat cgctttagac aactcttctg ttgaggcata ttcatttccc atctgcaagt
    34381 tgcttaaaat tgtcccgctg aataagaaag ccttctgagg gacataactg atgtgggagc
    34441 ggatctgttc ttgagtcatt tgagtaagag gaataccacc aagggttact tttcctatcg
    34501 tagggtcact aagtctcaag agaagtttcg ccaaactact ttttccagat ccggtcccgc
    34561 caacgatcgc tgttgttttt cctttaggta ttgtgaaatc aatatcttct agaactggat
    34621 cagagatttc agtatattta aatgtgacat gttcaaaagc agctgcattt gtctgatcaa
    34681 aggttggttc agctactgtt ttgatcgtct cttcctcaat ttcgatctct gcttgcagta
    34741 tttcttctat ccgtcgtaat gaggcaaacg atttagggat aatgaccaat accatagctg
    34801 cgatcatcaa gtaagcaagt gtcagcatag agtattcgac tacagcagtc acgacaccga
    34861 tttgtaatgc tccttctgct acaagatttc cgccaaacca caaaatagaa gcataaacga
    34921 ttcccatgag caaaaaagca attggagtga cccaagcaaa tattcggttc actttgatca
    34981 tttgattagc atagtcagca aagctcttat tcgttcgctt ttcttcatat gattgattat
    35041 caaaggcacg gatcatatta atcccagtaa agaattctct caatgtgatg gtgatccgat
    35101 ccatttttgg ctggatactc aaagataaag gtgcccctcg tttcatcagt cgataaacaa
    35161 tccatacata aaaaacaaca gagatcaatg taacccatgt tagtaataga gaataacgaa
    35221 acatcatgag aatggtgaaa acgcaaataa ccggtgctgg taagatcatt tggcaaaata
    35281 aaacaatcat ttgctggaca ttatcgacat cattcgtcat tcttgtcaaa agagatccag
    35341 aactaaaacg actgatatcc ttcattgaca gctgttggaa tttacggaaa tatttctccc
    35401 gcgtttggaa tccaaaccta gcggaagcca atgctgaaaa gtaactagag gcaactgcag
    35461 cgattgttcc tagaaacgct acaagcagca tttcaactcc aatttttttt ataactgagg
    35521 cttcgccact tgctatacct gtgtcgatca gctttgctac taattttggt acacctaatg
    35581 taccggcgat ttgtaaacag atcatcacaa aggtaaggag agcgagtcct ttgtttttct
    35641 gtaagaatgt ttttaagata gacatattat tcctcctttt ttcctgatac ttttcgattc
    35701 tataccttca agtaacttga aggtcaatag aaaaaagaat aaactgaaaa agaggtgaga
    35761 aaaaatgaaa aaaatgtata cgattggcca agtatcggaa ctatttgatt tgccaaaatc
    35821 aacgatccgc tattgggatg aacaaggatt aatccgttca agtagacaag aagagaatga
    35881 ttatcgattg tttgatatcg atgatatttt tatgctttat gatatcgttt tttatagaaa
    35941 attagatata ccgatcaaac agatgaagaa tttatatgga aaaacattga cggagttata
    36001 tgagacactt gatgaaacag aaagaagaat ccataaagaa ctggtggtga tgaaacaaaa
    36061 acaaaaagag ataagggagc gaaaaaaaca gttgaaattg atgatcgata caaacgagga
    36121 agaatttcct gtagaagaga tcccttttga ctgtatgatc tcaacggagt ttgaagatat
    36181 tgtggaaatc aaaaaatttc tacctaacta ttcaagcttt gggatgatga gtatgccagc
    36241 ttccagttca cagacgatgt atggattttt tatcgaccct agtgaagtac atttatttac
    36301 tcaagacgtg atttgggaga aaaaagatac ggctgtttat cgtcgattct tattgaaatc
    36361 cgagatgaac catgcggaac gtaataatat tttagaaatc agagaaagaa tgtatgaaaa
    36421 aggatggaaa acaggagaag tgatcggcca gtatctattg acgaatacgg atgaaaacaa
    36481 tatcagaact gaatattatc atgcatggat agaaatgaaa aaataggaaa tatgtgttta
    36541 agataactcg aaaatgatgg ttgttttagt tataaagaaa aattttctgg ttcgattacg
    36601 ggtttaatgt gggggattat tagtcgtgga tagatagaat tttagttttt tagaggaaat
    36661 atgtctttaa aaatggaatg gttgcaattc ttagcgatat atacgatgta attgtcctct
    36721 taaaaaagta tggaaaaata attgtattgg gtgttatgta taattcatgg tgaactgaga
    36781 ctaatgagaa gaaaaattca tattgttatg agtgagattg tatcagatga gaatgataaa
    36841 ttaaataggt gcataaaagc attacactta aaatacattg ttgcttacat tattacaata
    36901 tgttaataag gcaaaaataa atagatggat tgaataaaca tattttttaa tcaaatagtc
    36961 cctactgtga ctttcctcag ctatcggtga tactaccgat agcatttttt tgcttataaa
    37021 ataattataa gtatttagag atttttcttc taacattctt caaacaagaa aaatcacaaa
    37081 ggttattgtt atttttatat attcttttta agaatgatta tttttttata gaaattttaa
    37141 aaaataaaac acgttattga tggatagtta gtttgttatt tggtaatatt atagaagttg
    37201 actggtagtg atttattttt cgttgtttta taaaaatgtt attttttgga aaaaattcac
    37261 aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat gactaatata
    37321 aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg aatcaatgaa
    37381 ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata gcaatacatc
    37441 ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca acaaaaggat
    37501 taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt attctataca
    37561 aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat atatggtaca
    37621 gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga ttgtcactat
    37681 ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga ttaaggagtt
    37741 gatggaagac gatacaagtt aagaaagtaa aactacgccc aaataaagag caaaaagagt
    37801 aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt tattagtaat
    37861 gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt ttagttgaac
    37921 caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc aagtattcta
    37981 aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg atgaaggtta
    38041 accaatacag ggactcactg atgaaattct agagtctgac cttggtatca acgatttagt
    38101 gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat aactattagg
    38161 gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat aattatggtt
    38221 aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca gaagacaatc
    38281 ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac cgaaaatacg
    38341 agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat cgggtacctt
    38401 gttgtttagt caaaattata agggggagta atagtgagga acaaatttca taaactgtta
    38461 agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac ggttctagct
    38521 gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca agaggaggct
    38581 gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct aaatgcattg
    38641 gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa tgattacgaa
    38701 cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc aagaagcggt
    38761 gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag cacaagtgag
    38821 tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga agaaagctta
    38881 agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga atctcagatt
    38941 gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg ccccactttg
    39001 ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg cgatattctt
    39061 gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt aattgagttc
    39121 attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta ccaagaaggc
    39181 acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc cgctcagtcg
    39241 tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac tgagccaaat
    39301 aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga attttcaatt
    39361 acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc tagagaaatc
    39421 gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac caacagtaat
    39481 aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt ggttaccgat
    39541 gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc cactggaaat
    39601 agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg tgaagcaaac
    39661 gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa taaggaaacg
    39721 aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt tattgaatat
    39781 gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga tgggttttct
    39841 cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta ccgcttgaga
    39901 atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa aaatgttatc
    39961 aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc tggaacaagc
    40021 aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc atttctatca
    40081 gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt cagtgcgaat
    40141 aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt agaggcgtat
    40201 gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa tcgattgaat
    40261 acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa aactgatgag
    40321 aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc acaagtgata
    40381 caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc tgtaggtagc
    40441 tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac accaatcgag
    40501 tttgagatcg aaagaagtca gacagcggtg gtagaattga cgaaag
//
LOCUS       DACGMI010000024        39013 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.025, whole genome shotgun sequence.
ACCESSION   DACGMI010000024 DACGMI010000000
VERSION     DACGMI010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.025"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            188..418
                     /locus_tag="IXT46_001365"
     CDS             188..418
                     /locus_tag="IXT46_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAQ4947288.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            515..1816
                     /gene="murA"
                     /locus_tag="IXT46_001366"
     CDS             515..1816
                     /gene="murA"
                     /locus_tag="IXT46_001366"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAQ4947289.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1829..2005
                     /locus_tag="IXT46_001367"
     CDS             1829..2005
                     /locus_tag="IXT46_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAQ4947290.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2140..2436
                     /gene="yidD"
                     /locus_tag="IXT46_001368"
     CDS             2140..2436
                     /gene="yidD"
                     /locus_tag="IXT46_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAQ4947291.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2621..3088
                     /locus_tag="IXT46_001369"
     CDS             2621..3088
                     /locus_tag="IXT46_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4947292.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3173..4057
                     /locus_tag="IXT46_001370"
     CDS             3173..4057
                     /locus_tag="IXT46_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4947293.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4174..4407
                     /locus_tag="IXT46_001371"
     CDS             4174..4407
                     /locus_tag="IXT46_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAQ4947294.1"
                     /translation="MSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4495..4575
                     /locus_tag="IXT46_001372"
     tRNA            4495..4575
                     /locus_tag="IXT46_001372"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4529..4531,aa:Tyr,seq:gta)
     gene            4582..4653
                     /locus_tag="IXT46_001373"
     tRNA            4582..4653
                     /locus_tag="IXT46_001373"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4614..4616,aa:Gln,seq:ttg)
     gene            5168..5875
                     /locus_tag="IXT46_001374"
     CDS             5168..5875
                     /locus_tag="IXT46_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4947295.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5934..6578)
                     /locus_tag="IXT46_001375"
     CDS             complement(5934..6578)
                     /locus_tag="IXT46_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAQ4947296.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6704..6991
                     /locus_tag="IXT46_001376"
     CDS             6704..6991
                     /locus_tag="IXT46_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947297.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7099..7419
                     /locus_tag="IXT46_001377"
     CDS             7099..7419
                     /locus_tag="IXT46_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4947298.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7500..8813
                     /locus_tag="IXT46_001378"
     CDS             7500..8813
                     /locus_tag="IXT46_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4947299.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLSNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKIL"
     gene            8810..9529
                     /locus_tag="IXT46_001379"
     CDS             8810..9529
                     /locus_tag="IXT46_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAQ4947300.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9657..10208
                     /gene="raiA"
                     /locus_tag="IXT46_001380"
     CDS             9657..10208
                     /gene="raiA"
                     /locus_tag="IXT46_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAQ4947301.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10430..12964
                     /gene="secA"
                     /locus_tag="IXT46_001381"
     CDS             10430..12964
                     /gene="secA"
                     /locus_tag="IXT46_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAQ4947302.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            13090..14191
                     /gene="prfB"
                     /locus_tag="IXT46_001382"
     CDS             join(13090..13152,13154..14191)
                     /gene="prfB"
                     /locus_tag="IXT46_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAQ4947303.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14296..14982
                     /gene="ftsE"
                     /locus_tag="IXT46_001383"
     CDS             14296..14982
                     /gene="ftsE"
                     /locus_tag="IXT46_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAQ4947304.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14966..15859
                     /locus_tag="IXT46_001384"
     CDS             14966..15859
                     /locus_tag="IXT46_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4947305.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            16011..17459
                     /gene="cls"
                     /locus_tag="IXT46_001385"
     CDS             16011..17459
                     /gene="cls"
                     /locus_tag="IXT46_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAQ4947306.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEIAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYILQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17796..18653
                     /locus_tag="IXT46_001386"
     CDS             17796..18653
                     /locus_tag="IXT46_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAQ4947307.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18768..19688
                     /gene="pstC"
                     /locus_tag="IXT46_001387"
     CDS             18768..19688
                     /gene="pstC"
                     /locus_tag="IXT46_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAQ4947308.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19688..20572
                     /gene="pstA"
                     /locus_tag="IXT46_001388"
     CDS             19688..20572
                     /gene="pstA"
                     /locus_tag="IXT46_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAQ4947309.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVSEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20587..21393
                     /gene="pstB"
                     /locus_tag="IXT46_001389"
     CDS             20587..21393
                     /gene="pstB"
                     /locus_tag="IXT46_001389"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947310.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21409..22167
                     /locus_tag="IXT46_001390"
     CDS             21409..22167
                     /locus_tag="IXT46_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947311.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKNKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22180..22857
                     /gene="phoU"
                     /locus_tag="IXT46_001391"
     CDS             22180..22857
                     /gene="phoU"
                     /locus_tag="IXT46_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAQ4947312.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23094..24125
                     /locus_tag="IXT46_001392"
     CDS             23094..24125
                     /locus_tag="IXT46_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAQ4947313.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTNQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKHGLFALGSLIINIVLLLLLLLIFTKIEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNLWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            24122..24889
                     /locus_tag="IXT46_001393"
     CDS             24122..24889
                     /locus_tag="IXT46_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAQ4947314.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTTIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24989..26557
                     /gene="liaX"
                     /locus_tag="IXT46_001394"
     CDS             24989..26557
                     /gene="liaX"
                     /locus_tag="IXT46_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAQ4947315.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26857..27174
                     /locus_tag="IXT46_001395"
     CDS             26857..27174
                     /locus_tag="IXT46_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAQ4947316.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            27174..27524
                     /locus_tag="IXT46_001396"
     CDS             27174..27524
                     /locus_tag="IXT46_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAQ4947317.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27691..28629
                     /locus_tag="IXT46_001397"
     CDS             27691..28629
                     /locus_tag="IXT46_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAQ4947318.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28644..29474
                     /locus_tag="IXT46_001398"
     CDS             28644..29474
                     /locus_tag="IXT46_001398"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAQ4947319.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29518..30543
                     /locus_tag="IXT46_001399"
     CDS             29518..30543
                     /locus_tag="IXT46_001399"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAQ4947320.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHCLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPVEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30558..31496
                     /gene="galU"
                     /locus_tag="IXT46_001400"
     CDS             30558..31496
                     /gene="galU"
                     /locus_tag="IXT46_001400"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAQ4947321.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            31621..32061
                     /locus_tag="IXT46_001401"
     CDS             31621..32061
                     /locus_tag="IXT46_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAQ4947322.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLKVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            32064..32666
                     /locus_tag="IXT46_001402"
     CDS             32064..32666
                     /locus_tag="IXT46_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAQ4947323.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(32725..33831)
                     /locus_tag="IXT46_001403"
     CDS             complement(32725..33831)
                     /locus_tag="IXT46_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAQ4947324.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            34041..35042
                     /gene="ccpA"
                     /locus_tag="IXT46_001404"
     CDS             34041..35042
                     /gene="ccpA"
                     /locus_tag="IXT46_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAQ4947325.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(35379..37724)
                     /locus_tag="IXT46_001405"
     CDS             complement(35379..37724)
                     /locus_tag="IXT46_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAQ4947326.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            38003..38905
                     /locus_tag="IXT46_001406"
     CDS             38003..38905
                     /locus_tag="IXT46_001406"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAQ4947327.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
BASE COUNT        12721 a         6753 c         8368 g        11171 t
ORIGIN      
        1 tttggaataa gggactgcga caagactttt gtctcagtcc ctttttttgc atatttttag
       61 catttatttc ctaaaaaatg taaggggatt cctatatttt taagtatact tgtttttcct
      121 tttatacatt ttatggtatt atcattttat tagttattat aaaacaatcg ttagaaagga
      181 cgtcattatg caagtatacg gaattgatgc ggtgcttcga atcgtgagtc atttggcgtt
      241 tatctactta gccttctggt ctttacgttc gttacgcatt gaaacttttt tcagaccaat
      301 gcataatacg caaattagaa tggcaatcgt acttttttca atttttttag ggtacactgc
      361 aagtaatttt ttcttagaag ttatcgcttt atgccgaaat cttttcgtta gcctgtaaat
      421 tttaaaaaaa ggtactattt taaaagcaag gatgttataa tagaaaagat tttgagtaag
      481 tgtatgctca ttggaatttt ttggagggaa caacatggaa gagatcatcg taagaggtgg
      541 caatcaatta aatggaacag taagaattga aggagctaaa aatgctgttt tgcctatttt
      601 agctgctagt ttgttagcag aagaaggtat tacgacatta gacaacgttc cgattctttc
      661 tgatgtcttc actatgaatc aagtgattcg tcacttaaac gtagatgtag attttgatga
      721 acaaaagaat caagtaacaa tcgacgcttc aagacaatta gaaatcgaag cgccttatga
      781 gtatgttagt caaatgcgtg cttcaatcgt tgtgatgggt ccgctacttg ccagaaatgg
      841 acatgcaaaa gtagctatgc ctggtggatg tgcgattggt aaacgaccaa tcgatttgca
      901 tttaaaagga tttcaagctt taggagcaaa aattattcaa aaaaacggct atatcgaagc
      961 aattgcggat gaattgatcg gtaacacgat ttatttagat ttccctagtg taggtgctac
     1021 tcaaaatatc atgatggctg ccgtaaaagc aaaaggaaca accatcattg aaaacgtagc
     1081 tcgcgaacca gaaatcgttg atttagcaaa cattttgaat aaaatgggcg ctcaagtcta
     1141 tggagctggt actgaaacaa tgcgtattga aggcgtggat catttacatg cagtcaacca
     1201 ctcaatcgta caagatcgta tcgaagcagg tacctttatg gttgctgctg caatgacaca
     1261 aggcaatgtg ctgattgcag atgctatctc tgaacataac cgcccattga tttctaaatt
     1321 gatcgaaatg ggtgcagaaa tcattgaaga agaaggcgga gtccgtgtca tcggaccaaa
     1381 acatatctta cctacagatg taaaaacgat gcctcatcct ggtttcccta cagatatgca
     1441 agctcaaatg acagctatcc aattagttgc agaaggtaca agtgtagtga ctgaaacagt
     1501 gtttgaaaat cgtttccaac atttagaaga gatgcgccgt atgaacgctc atgtcaaaat
     1561 cgacggaaat gtagcaatca tggatggaaa ccatgaattg caaggtgcag aagtatatgc
     1621 aacagacttg cgggcagcag cagcattagt tttagctggc ttgaaagcaa atggaatcac
     1681 acgtgtgcgt aacttgaatt atctagaccg tggatattat aatttccata tcaaactaca
     1741 gcaattaggt gcagacgttg aacgtgtaga catggatcaa acttctgctg aaaaaacagc
     1801 acaaacgatt gcttaaggaa gtggctgaat gagtaaccaa cgatatatct tattaacttt
     1861 gataaagatt ttaatggtga tcttattgct tatccttctt tttgtggccg gaacgatgat
     1921 cggatatggt gtcatcggtg gcggcaatcc atttaaagta tttcagccaa gtttgtggat
     1981 tcatattcga gacttttttc attgataaat aagaatcaca gtggttctag tcgatatgaa
     2041 gtgagccatg aagcagaaca tgataaaaga aaacagaagg gaacgttgac gttagtcgcg
     2101 atcccttttt ttagtaaaag aaaagaagga atctaattga tgaagaagat attgatttat
     2161 ttagttagag gatatcagcg ctttatttcg cctgcatttc cacctagctg ccgttattac
     2221 ccaacctgtt ccaattatat gataaaagca attcaaaccc atggcgcgct aaaagggacg
     2281 gtaatgggga ctgcacggat cttacgctgt catccttttg tcaaaggcgg tatcgattat
     2341 gtaccattga cattccgatt aacgcgaaat aagaaagata aaaaagaacc agattataaa
     2401 aaggttgtga aaaatacggg tagcactgag cgataaagaa acaatttgga aaatagcttc
     2461 ttatattttg caaaattgtg agttattgcc gaagtgttgg attttgaaca ccgtcaaaaa
     2521 aaaggttgtg aaaaatacgg ctagcactga gcgataaaga aaaagaggaa atttattgtc
     2581 aaagtaacaa ctccgcaact acttatatgg gggacaaaaa atgatcgaag aactaaacaa
     2641 gaaagattta ccatggtcct tgttattaga tgcagatcct gataaagaaa aagttcaagt
     2701 atatgtttcc agagggagtg gctggatatg gaaagaaaaa gaaaaaacaa taggtgtact
     2761 gatctatgtg gcaagggaaa aagaatacga aatcgtcaat gtagcagtaa ccccaacgta
     2821 tcaaggaaag gggattggcg gaaaattact tgagacagct tttcagaagc tttcacaact
     2881 cgcttccagt caaactcaga tcatcatacg aaccggcagt actagcagtg cggcgttaca
     2941 tctctatcaa aaaatgggct atgtggagat tggtcgagtc aaagactatt ttatccatca
     3001 ttactctgag cccatttttg aaaatggaga tcaattaagg gatcaagtga ttttagcaat
     3061 tcacttacct aaaaatagct ttaactaata aaatttcaat tcaagaaaat gctttcaaat
     3121 gctaaataga tacattacaa tagctttagc aaacaaaaag gagaatattt ttatgggaat
     3181 attagttttt gattttggtg gatcggctgt caaatatggt tgttgggatg gcaaagagat
     3241 taaaggtaag ggacaatttg caacgcctga atcttgggaa gaaatgaaag cgcaattatt
     3301 tcaagtttat aaaaaaatac tcgtttcttt tgaagtcgaa ggaattggaa tcagctctcc
     3361 tggagtagtg aataatgaga aacaggtgat tgagggaatc agtgcgattc cttatattca
     3421 tggatttaat attttccgag atttggaaac tctgtttcaa cttccagtaa cgattgaaaa
     3481 tgacgccaac tgtgccggaa tggctgaatt ttatgaaggt gctgcccgcg attatcaaga
     3541 tgttgctttt gttgtggcag gaactgggat tggcggggcg ttgttcacga aaggacaaat
     3601 caataaaggg gcacatcttt acggtggaga atttgggttg atgttcttaa atggcgataa
     3661 gacattcagt aaacttggta cagcggtaca gatggcttgg cgttattgtg aacgcaaagg
     3721 tctcgataaa aatgcttata ccggaaaaga tgtctttgaa ttagcagaaa ctggagatgc
     3781 aatagcaaaa gaagaagttg agagttttta tacgtatctt acaaagggat tattcagtat
     3841 tcaattttcg tttgatccag aagtgatcgt attaggcggc ggggtttctg caaaagaagg
     3901 gctcattgat gagatcaaaa gccgaatgaa gaagctgaca gaacaattcg atctgcatga
     3961 tttcgaaccg cagattttat tatgtgaata cagaaacgat gctaatcttg taggtgcagc
     4021 agcaaactat ctcgctgtac gtcaagggga gaattaagag ctttagagaa ggtgcagctt
     4081 gcataaaaga agtgaatgaa atgaatagga gatttttacc taaggaatgt tttatttgct
     4141 gcagtatgat aaaatatctg agaggtgaaa atgatgtcaa aaaaaaataa agatattgaa
     4201 gtgcgtatag aagaagtgaa aaaagatatc aaaggtaaga attatgaagt cactcagtta
     4261 tttataggga aaaaaatgat tggtgagatc ttagcctatg gaccaaaaga atatgaaatt
     4321 ttctttggtg aagaagattt tggaaaagaa aaaagtcttg aaaatgcgat agaaacagtg
     4381 attcgacact ggaatctgca cgaataaaaa aatatcaaaa aaactttcaa taaagggttg
     4441 caaaaatctg gaaaattagg tattataact aagtcaggtt gatacaaacc tttcggagga
     4501 gtagcgaagt ggctaaacgc gacggactgt aaatccgttc cttagggttc agtggttcga
     4561 atccactctc ctccatttca ttggggtata gccaagcggt aaggcaaggg actttgactc
     4621 cctcatgcgt tggttcgaat ccagctaccc cagtatacca caatcgtaag ctctcgttag
     4681 ttcgagagct cttttttttg ctttgctacc ttgttccttg aagattctgc tgatttaaga
     4741 tagagttaag ttaactacaa gaattggagg gatccacatg aaatggaaag aaaaagtaga
     4801 cgaagcagct gaaaagttat atgatttggt caaatcagaa aaatacaata ttgaagtgaa
     4861 tattccgaaa aaaggcggaa aagcggtccg ggtaaaatca aaacgcccaa cgaatcatac
     4921 aaaaaaatgg atggctaaaa accgctaata ataacaaaag atccataagt cggcattttc
     4981 atcgatttta gggtcttttg ttattttcta ggttggacat atctaaaaaa ttgtttctga
     5041 caataggagt aggaagaacg atgtgtgtct aaatcctctg ttgatggata gaaaccttta
     5101 tctttttcag ttgtgaatca ggtatatacc agttataata gaagaaacga aaggacgggt
     5161 gtacgttatg tcgaatcaat tacctgtata tatacagatt catgaccaat taaaaaatga
     5221 aatcgaacaa ggtatatgga aagtcggaga ccgtcttcct tcagaaagag aattagcagt
     5281 gaaattcaat gtcagccgta tgacgttgag acaagcaatt caaaacttgg cagatgaagg
     5341 aatcttagaa agaaagatcg gttcgggtac atatgttgca cgagaaaaag tacaagaaaa
     5401 aatgtctggt gcaacaagtt ttacagaaat tatggaatca caaaatcgag taccgtctag
     5461 tcggacaatc tcttatttct tgacttcgcc aagctcaagt gaaatggaaa aactaaactt
     5521 gagtaaagat gacacgatct tgcgaatgga acgtattcgt ttcgcagatg atgtccctat
     5581 ttgttttgaa gttgccagtg tgccacaaaa gctgatcgat ggctacagca aagcagagat
     5641 tactgaatcg ttgtatcgca cgctagaaga aaaaggcggg aaaaagatcg gtccagcgaa
     5701 tcaaacgatt actgctgtgt tggcttctga gaaaattgct gactatttag aggtaaaacg
     5761 aggagatgca gttcttcgtt tgcgccagat ttcttatttt gaagacggta cgccgtttga
     5821 gtatgtgcgt acgcaatacg taggaaatcg ttttgagttt tatttggaaa aataaaaaac
     5881 aggtgatccc tgattccgta ttagaaataa aagagaatca gaatcacctg tttttatata
     5941 tgatcagtta ccagttgctc gtgataagaa acaggaccct cttcaaattg gacttgtccg
     6001 ttcagcagct caatgatgga ttctttaaag tggtcagcac ttttttcatc tacagcacag
     6061 atgacgctaa cttgatcagt atattggatt tcttttataa aaaaatgttg gagttcaaga
     6121 taattctgta attttcctag ttgcggatac gtgatcatca cagagatctc ctgttgcaag
     6181 gtaccttcta cgattccaat gtcagacaat gcttgagaga ccgcatgagt gtatgctcgt
     6241 attaatccgc ctgtgccgag tttcgttcct ccaaaatatc gagtgactac tgcagctaca
     6301 ttgatcagtt gatttttttt gaggacttcc aacatcggta tgcccgccgt tccacttggt
     6361 tctccatcat cgctgcttcg ctggatttca tttttttctc caatgatgaa ggcgctgcag
     6421 ttatggttcg ctttccaatg ttcttttttt atttcttgaa tgaaactttt tgcttcgtcc
     6481 tctgattcta ttcgtctaag agaacagata aagcgtgatt ttttgatctc gatctcactt
     6541 tgtccatttt cttttattgt acgatagcgc tcgatcatct tgtcacctct tttttcattt
     6601 tctttattca gtataaataa agttctaggt tgtttcaaca ctgtaacggt tgcgcaattg
     6661 ctgtagtatg cgataataaa gacaaaggca ggtggatctg gggatgcagg aacgaatgaa
     6721 aaagtacgat gcaattacgc attatttgaa gaacaatggc ggctctcaag taacgttgac
     6781 ctttacccaa tttgacgaac tgctgtttcc cagtaacgga cttcccaaaa cagcaaggga
     6841 aagtacagat tggtgggcaa atgattataa acaccctgaa aaaggtgcct atggctggat
     6901 aaatgcaggc tatgaagtag ttgtcatcaa tttggacaaa gaatatgtcg tgttcaataa
     6961 attagtgaaa tctagttggc tatttgatta aataaaccgc gtttagaaaa cgttgacaaa
     7021 tttctttctt tttatataat agagtaacag acgcgaagaa aacgtttgcg tagtttgttt
     7081 taaaaaggag agaaaagtat ggctaaaaaa acaatcatgc ttgtatgttc ggctggtatg
     7141 agcacaagtt tactagtaac aaaaatgcaa aaagctgctg aagcaaaagg aatcgactct
     7201 gatattttcg ctgtgtccgc ttctgacgca gataacaatc ttgcaaataa agacgtggat
     7261 gtgttgttat taggcccaca agttcgcttt atgaaagctg attttgagaa acgtctggaa
     7321 ccaaaaggca ttcctttaga tgtcatcaat atggctgatt atggtatgat gaatggcgaa
     7381 aaagtgttag atcaagcaat cacgctcata ggtgaataaa tagaacagta taactatcga
     7441 acaagcgatc caaaaaatag atcgcttgtt ttttcgtata tttttttagg gcgaataata
     7501 tgaatcattt ttggggtaga aggcttctga cgagagatat taaagcaata gactgtgagg
     7561 aggtaaattt accaaattat gagaagatcg cagcagtgga acgtttgagc aactggattc
     7621 tttgtcatcg ctgtggaatg agaacgtccg tcattgatgg acagcttgca gattacggtt
     7681 atttttgtac acattgtcta tatttagggc gatgcgacac tcaacaagat ttatatttgt
     7741 ttgatcagcc tgaagcaaaa cctcgagaag tcgtcttttt ttggacagga cagcttactg
     7801 aaaaacaaac ggaaatctca aagagaatac tttgccattc agaaaaaaga catcatctta
     7861 tttgggctgt aacaggtgca gggaaaacag agatgcttta tcctatttta gtggaaactt
     7921 taaaagctgg aggaagagta gcgatttgta caccgcgagt cgatgtttgt aatgaattgt
     7981 ttttacgcta tcgttatgtt tttccagaag aaaaaatcac gttgctccat gggaatacag
     8041 caacggctta tacctttact tcttttgtta tctgtacgat tcatcagcta taccgttttt
     8101 atcggtcctt tgatttaata gtgatcgatg agatcgatgc gtttccttat aacggggatg
     8161 caggattagc tcatgctgtg caaacagcga ttaaaccaga cggacgattc atctacttaa
     8221 gtgccacacc tgataaaaag ttactaaagg agatcaagca gacgtttgac atccacaaac
     8281 ttgctttacg ctttcatcgg cgtttgcttc ctgaacccgt cttggttttc atgaataatt
     8341 ggcgacaaaa atgcaagaac aagaagaaga taaaatcttt ggtgcggatc attcatcaat
     8401 taattaaaga aaaccatatc cttttatttt gtccaagtat cacgatgatg catcgtttga
     8461 aagccacact tcaagaggct cttccgagat atgagatcac agatgtttct tcaagagaca
     8521 atcagcgggc ggaaaaagtc cagaaaatgc gagaagcaaa atatgacata ctgttaacca
     8581 cgatgatcct tgaacgtgga gtcacatttg aaagaatatc cgttatcgtt ttaggagcgg
     8641 atcatccggt ttttactaaa tcttctttgg tacaaatcgc aggaagagcc gatcgtaaag
     8701 ggccttatac gaacagtcaa gtatattttt tctatgaaga aaaaactgca gctattcgaa
     8761 aagcttgtca ggaaatcaaa gaaatgaatg aagaagggaa gaagatactg tgaggtgcag
     8821 ttgctgcagt aaagatatcg tccaaaattt aacattcagc gagattattg gtgtttcgaa
     8881 atacagatta cctcagactt gttcagtttg tcgcgcacaa tttcatttat tggaaacaag
     8941 aggctgttct ggctgtcaaa aaccaatcca tttcaatcta gagagtacga aaaagaaagt
     9001 aaattctatc cccgtttact gcagtgactg tcaagaatgg aagaagaaat atccgaccta
     9061 tgattttcag caccgtgcct tttttgtgta cgatgaaaat atgaaggcct ggctcaatca
     9121 atacaagttt atgggagata tccgactagc aggcaccttt gcatataaat ggacgcagat
     9181 aaaaaaagaa tacccgacat acatctattg tccaatacct ttatctgaaa aaaggcgaac
     9241 agaaagagga ttcaatcaag taagcgagat gttgaaagca gcaagaattc cttttcagat
     9301 gctactcaaa agagagaagc atctgctggc tcaagcaaaa aacacgcgaa aggaaagatt
     9361 ggagatgcct caaccttttg aacttgcagt caccttttct aagatacaaa ataaaaaaat
     9421 attgattatt gatgatgtct atacaacagg acagactctt ttccacgcag cagattgttt
     9481 gcagatcgca cagccgaaaa tcatccgaac tatttctttg gcgagatgaa ttagatgtgg
     9541 aaatttgata gcgatttaat ttgcaaataa cctagagttc gatataatag aattaagaag
     9601 agggaaagag tggtccttct ccttcttgat tgtggtagac gaaaggggta atttttatgt
     9661 ttagatataa tgtacgcggc gaaaatatcg aagtaactga agcgattcgc gactacgttg
     9721 agaaaaaagt aggcaaacta gaacgctatt tcagtgacgc acccgatgca acggcgcatg
     9781 tgaacttaaa agtttataca gaaaaaacag caaaagtgga agtaacgatc ccattacctt
     9841 atcttgtatt acgtgccgaa gaaacttctc cagatttata cgcaagtatc gatttggttg
     9901 ttgacaaatt ggaacgccaa atccgcaaat tcaaaacaaa aattaatcgt aaatcccgtg
     9961 aaacgggcat gaatactgca aatgctgctg ctttattcaa tgaagaggac gaaaacgaaa
    10021 atgattctga attagatatc gtacgtacga aacgcctttc attgaaacca atggatagtg
    10081 aagaagcagt cttgcaaatg aacatgctgg gacataactt ctttattttt gaagatgcag
    10141 aaacaaatgg tacaagtatc gtttaccgcc gtaaagatgg aaaatacgga ctgattgaaa
    10201 cagactgatc agccttactt aaataacaac gaaaacttgc agcagctact gacagctgcc
    10261 gcaagttttt ttgagtttcc tcctctttta gatgaaatat gaataaatta tgaagttctt
    10321 actttaatac gcttaagata tttcaattat ctataactaa tgataaaatg aaaagtaaag
    10381 tctacatagt ctggataata cacagaagga aaaggagatt acacaacgca tggccaattt
    10441 gattcgttca cttatcgaaa acgataagaa agaactaaaa cgtttagata gcattgcaaa
    10501 aaaagttgaa gcatacgctg accaaatggc agcattaact gatgaacaat tacaggcaaa
    10561 aactgctgaa ttcaagggca gataccaaaa aggagaaaca ttagatcaat tacttccgga
    10621 agcttttgca gtcgtccgag aagcagcaaa acgtgtatta ggtttatatc cataccacgt
    10681 acaattgatg ggtggaatcg tgcttcacga tggaaatatc cctgaaatgc gtactggtga
    10741 aggtaaaacc ttgaccgcaa cgatgccagt atatctaaat gctctgactg gcgaaggggt
    10801 acacgtagtt accgtcaatg aatatttagc aacccgtgac tcgacggaaa tgggcgaact
    10861 ttataatttc ttaggattaa cagtggggtt gaatatcaac tcaaaatctt cggatgaaaa
    10921 acgcgaggct tataattgtg atatcactta tagtacgaat aatgaattag gatttgacta
    10981 cttgagagac aatatggtcg tttaccgcca tcaaatggta caacgtccgc tgaattatgc
    11041 cattgtcgat gaagttgact caatcttgat tgatgaagcg agaacgccgc tgatcatttc
    11101 agggcaagca gaaaaatcca cagctttata tacaagagca gacaacttcg tgaaacgttt
    11161 gaaagaagaa gaagattata aaatcgatgt acaatcaaaa acaatcagtt taaccgaagc
    11221 agggatcgaa aaagcagaag aaacattcgg tttggataac ttatacgaca ttgaaaatac
    11281 tgcattgacc catcacttgg atcaagcatt gagagccaac tatatcatgc ttttagatat
    11341 cgattatgtt gtccaagacg gaaaagtact gattgttgac cagttcactg gtcggatcat
    11401 ggatggacgc cgttattcag atggacttca ccaagcaatc gaagctaaag aaggcgtaga
    11461 gatcgaagac gaaacgaaaa ccatggcgac gatcactttc cagaactatt tccgtatgta
    11521 caagaaactt gcgggaatga ctggtacagc taaaacagaa gaagaagaat tcagagaaat
    11581 ttataacatc caagtatacc agattccgac aaatcgtccg gttatccgtg atgatcgtcc
    11641 agatttgctt tacccaacat tacaaagcaa gttccacgct gtcgtgcaag atatcaaaga
    11701 tcgctaccgc aaaggtcaac ctgtgttagt cggaactgtt gcggttgaaa catctgagtt
    11761 attatcagat atgctgaatc aagaacgtat tcctcatgaa gtgctgaatg cgaaaaatca
    11821 ctttaaagaa gcagagatca tcatgaatgc tggtcaaaaa ggtgctgtga cgattgctac
    11881 caacatggct ggtcggggaa cagatatcaa gttaggactt ggggtaagag aacttggtgg
    11941 tctagcagtt atcgggacag aacgacatga atctcgtcgt atcgataacc agcttcgagg
    12001 acgtgcagga cgtcaaggag accctggtat gtcacagttc tacttgtcat tggaagatga
    12061 tttgatgaaa cgattcggtt cagaacgaat caaagctttc ttagatcgga tgaagatcgg
    12121 tgaggaagat gctgttatcc aaagcaagat gctgacgaaa caagtagaat ctgcacaaaa
    12181 acgtgtagaa ggaaataact atgacacacg taaaaacgtc ttacaatacg atgatgtgat
    12241 gcgtgaacaa cgtgaagtaa tctataaaca gcgacaagaa gtaatcatgg aagaaaaaag
    12301 cttatccaag ccactaatga acatggtcaa acggacaatc agtcgtgtag tagatgcgca
    12361 tacacaatta gagaaagaaa attggaattt ggaaagtatc atcgattttg ccggcagtac
    12421 tcttgtccat gaagatagta ttactcttgc agatatcgaa ggaaaaacag ctcaggagat
    12481 caaagagtat ctaaacgaac gagcacaaga agtatttaat accaaagcgg ctcaactaaa
    12541 tggtccagag caactgttgg aatttgaaaa agtcgtgatc ttgcgtgttg tggactctaa
    12601 atggacagac catattgacg caatggatca attacgtcag tcaatcggct tacgtgctta
    12661 tggacagaac aatccattag tcgaatatca aacagaaggc tataagatgt ttgaagatat
    12721 ggtaggcgcc atcgagtatg aagtcactcg aatctttatg aaagctgaga tccgtcaaaa
    12781 cgtacagcgt gaacaggttt ctcaaggaac agcttctcac tcagaagacg gagatgccaa
    12841 agaaaatagt aatactagcg cgaaaaaaca gccaatccat gtgaacaagg tcggaagaaa
    12901 tgatccttgt ccttgtggaa gcgggaaaaa atataagaac tgtcatggaa aaaatgcaaa
    12961 ctaatttctg acagcaggat tggtgagaca aattcttttt ttaagaattc gtctcacctt
    13021 ctttctgtta tttgctgatt ctgttagact agatataatg aaaaaagtat agtgaaagaa
    13081 ggaaaaaaca tggaaatatc cgaaattcga aatctcctga cagaaatgca ggaaaaggtc
    13141 acaagtttca ggaggtctct ttgacttaga tcagctggaa gaagacatcg cggaagcaga
    13201 agcaaaaatg gctgaacctg gtttttggga tgacagcgaa gccgcacaaa aagtgatcag
    13261 tgaaaataac gctaataaag aaacctatga ccaattccat tctcttgccg aagaactaga
    13321 agaaatcgaa ttgatggtgg agatgctgca agaagaacct gatgcagcaa tgcaagaaga
    13381 agcagaaaca cgtatcaatg cattagatga aaaaatgaag acgtatgaat tatctatgct
    13441 gttagacgga ccttatgatc gaaacaatgc gatcgtcgaa ttgcatccag gggctggcgg
    13501 aacggagtcc caagactggg gcagcatgct tttacgtatg tatacacgtt gggcagagca
    13561 gcatggctat caagtagaaa cactagatta tcaagcaggt gatgaagcag ggatcaagag
    13621 tgtgaccctg ctgattaaag gacataacgc ttttggttat ctaaaatcag aaaaaggtgt
    13681 tcatcgcctt gtacggattt cgccttttga ctcagcgaaa cgacgtcata cttctttttg
    13741 ttcggtagat gtgatgccag agcttgatga aacgatcgat atagaaatca atccagatga
    13801 tttgaaaatc gatacgtacc gagcaagtgg tgcaggtggt cagcacatca ataaaacaga
    13861 atctgctgta cggatcactc acttgcctac aggaacagta gtagctagtc aggcacaacg
    13921 ctcacaattg aaaaaccgtg agcaagcgat ggggatgtta aaagctaagc tttatcaatt
    13981 agaagtggaa aagaaagaac aagaagcagc tgcacttcga ggagaacaaa aagaaatcgg
    14041 ctggggttca cagatccgtt cttatgtttt ccatccctat tctatggtaa aagaccatcg
    14101 gacaaacgta gagacaggaa atgtccaagc agttatggac ggtgaccttg atttatttat
    14161 tgacggctat ttaaaaatgc atctacaata agaacccatt gttaaattga aataaaattg
    14221 taagattttg caagcatgtt gaaacattgc catgctataa tagctaaaga ctgaaaaaga
    14281 tatggagaga acgccatgat tgaaatgaag gatgtaatga agaagtactc aaatggtacg
    14341 accgctatcc gcaatctctc gattgtcatc gaacaaggag agtttgtcta tgtggttggt
    14401 ccgtctggag ccggtaaatc tacattcatc aaattgatgt atcgagaaga aaaagcttca
    14461 aaaggaactt tgaacgtcgc aggtcatgat ctaatagcaa tcaaaaaccg cgaagttcct
    14521 tatctacgca gagaaatcgg cgtggtgttc caagactata aattattacc aagaaaaaca
    14581 gtatatgaaa atgttgcgta cgctatgcaa gttatcggca gaaaacctcg agatatcaaa
    14641 aaacgagtaa tggaagtgct ggaccttgtt ggtttgaaac acaaagttcg agtctttcct
    14701 agcgaattat ccggtgggga acagcaacgt gtctctattg ctcgggcaat cgtgaatacg
    14761 cctaaagtac ttatcgcgga tgaaccgaca ggaaatctgg atccagaaaa ctcatgggaa
    14821 atcatgaaat tattagatcg gatcaatgcc caaggaacta ctgtcgtgat ggctacacat
    14881 aacagtacga tcgtaaatac gattcggcac cgagtaattg ctatcgaaaa cggccgcatt
    14941 attcgagatc aagcggaagg ggaatatgga tacgatgatt agaacctttt tccgccattt
    15001 attagaaagt atcaagagtt tgaaacgtaa cggctggatg acagttgctt cagtcagtgc
    15061 ggtaacgatc acgttgactt tagtcggtgt attcatggca gttatcatga atgcaactaa
    15121 attagctcag gatatagaag gaaacgttga tgtatctgta ttcgtagata tcggtacaaa
    15181 agacgaagag atgaaaaagc tagaaaaaga attgaatgac ttagatcatg ttaaaaaagt
    15241 tgaattttca agtaaagaac aggaattgaa aaaaatccaa aacgaaatgg gtgattcctg
    15301 gaaattgttt gaaggtgaca ataacccgtt atatgatgtg tatgtagtaa gtgctactga
    15361 tccttcttat acaaaacaag tagcagaaga agcagcagat ttgaagaatg tttctcgttc
    15421 tgattacggt ggagcttcct cagatcggat tttccaaatc gctggtgcag ttcggacatg
    15481 gggattagtt gcagcggcat tgctgctgtt cgtagcgatg tttctcattt cgaacacgat
    15541 tcggatcacg attttgtcta gacagcgtga aattcaaatc atgcgtttag tcggtgcaaa
    15601 aaatggatat attcgctggc cgtttttcct tgaaggtggc tggatcggtc tgatcggtgc
    15661 gattcttccg attttgatca tcacatttgg ttatgcatgg tttttccaat tgatcaatcc
    15721 atcattatta cgttcccatt attcattgat tcatccacaa aatatcgttt ggaaaatcaa
    15781 tcttttaatg gtcggcattg gtgtgatcat tggttcactt ggctcgatca tttctatgag
    15841 acgtttcttg aaattctaat accacaatat aaataaaatg agaaagttgg acagtttcgt
    15901 tccagctttc tttttttatt ggctaggaga atagaaggaa gcggcttttt tccctttact
    15961 ttaaaaaaca acttgggtat tcttaagttg gtagaggaag aggtgaagcc gtgaaaatta
    16021 tcgttgacaa tttttttacg atccttttga ttatgaatat tttgctttcc tttatcatcg
    16081 tttttcgaga aagaaaggaa actgctcaaa catgggcatg gctgctcgtt ttgatgttca
    16141 ttccagttgt aggatttatt ttatatattt ttttaggaag agggatttcc aaagagaaaa
    16201 tctttgattt gaagatccaa gggaaaatcg gtaagaacct ggaaattgaa gaagacaaac
    16261 aggcattgat gcgagggctt tatcctcatc cgcctactgg acaagtagat gtgaaacaat
    16321 tgatctatat gctcacggta tttgaaagta cgctctatac gactaaaaat gaaatcactt
    16381 tatttacaga tggtcgtgaa aaattcgatg cgctgattga agatatcaag caagcagaag
    16441 accatatcca cttccagtat tatatttatc gcagtgatgc attaggtgaa gaagttcgag
    16501 atgcattgac agaggcggca agacgagggg taaaagtcag agtccttctt gatgcatggg
    16561 gttccacaca agtttcttcc agcttttttc agaatttgaa aaaagcaggc ggagaaatcg
    16621 catttttctt tcctctattt gttccgtata ttaatcctcg gatcaattat cgcaatcatc
    16681 gtaaaatcgt agttattgat gggaaaatcg gatatacagg tgggttcaat gttggaaatg
    16741 aatatctagg attggtaaag aaatttggtt attggcgaga caatcatttg cgtatttacg
    16801 gagaagcggt gtatatcttg caaaaccgtt ttttgatgga ctggaattct cagcatacaa
    16861 aagaagtagg ctattctccc aaattttttc cgtccattca ctctactggt gatatagctg
    16921 ttcaaatcgt gacaagcgga ccagataccg aacatgaaca aatcaaaatg acttatttga
    16981 aaatgatttc gttagccaaa cgggagatat tgatccaaac gccttattac ataccggatg
    17041 gatcgattca tgaagcactg aagttggctc ttctttcagg cgtaaaagtt catatccaaa
    17101 tacctaacaa accagatcat cttctcgttt actgggcaac gtattctttc gctgcagagc
    17161 tgatcgagta tggagcaagg atcgaaacat atgagaatgg atttattcat gcaaagacga
    17221 tgattatcga tggtggcatt gtttcagttg gctcagcaaa tatcgatgtt cgttcatttc
    17281 gcttggactt tgaggtcaat acactgattt atgatgaacg aatggcttca cgtgtaagaa
    17341 aagcattttt tgaagactcg aaaatttcta cgcatctcac aaaagaaatg tatgaaaacc
    17401 gaggaataat catcaagatg aaagaaggat tagcaagatt gatttcgccg ctcctttaaa
    17461 acacaaaaag gacatgagaa ccatcaacag atggagatct cgtgtccttt tctaacgggg
    17521 ccatttctga gagtacgtca gaaatggaga aagcgtctcg catgagcgaa attaactttg
    17581 gggtatctct tgttttttgg ggaaagcaag aaataagcta atatatgcta ttaaaagaga
    17641 cacatttcaa agccagtata gcatagaaac ttttaatgag atagtttttt ttacaattat
    17701 gaggatttat tttgttattt aatgattttg attcgttttc atcaagtaat gaaaatgata
    17761 aaataaacat actttaggat taaaggagat ttctaatgaa aaaacttaaa ttattcttac
    17821 caataatagg attagctatt cttttatcag gctgttcaaa gtggattgat cgaggagaat
    17881 ccattacggc tgttggctct tctgctttac agcctttagt agaaacagtt gctgaaactt
    17941 accagacaga aaatcctgga aaattcatca atgtacaagg gggcggaagc ggaactggtt
    18001 tgtctcaagt acagtcagga gcagtcgaca tcggaaactc tgatttgttt gcggaagaaa
    18061 aatcggggat cgatgcctca gcattagtcg atcatcgagt agcagttgtt gggatcactc
    18121 ctattgtgaa caaggatatt ggcgtaaaag acatcagtat ggaaaacctg aaaaaactat
    18181 ttacaggcga gatcaaaaac tggagtgaag tcggtggaaa agatcagcca gtagttatat
    18241 tgaaccgtgc ttcaggaagc ggaacccgta gcacgtttga aaaatgggta ttggacggag
    18301 aaacagctgt tcaggcacaa gaacaagatt caagcggaat ggtgcgccag atcgttgccg
    18361 acacacccgg tgcaatcagc tatgttgctt tttcttatgt ttccgatgat gtagatacgt
    18421 tgaatgttaa cggtgtagaa ccgacagatg aaaatgtgac aacgaacaaa tggacgattt
    18481 gggcatatga gcatatgtac acaagagatc atccaaaaaa actgacaaaa gaatttttag
    18541 actatatctt atctgatgaa gtacaagata acatcgttgg agaactaggt tatatccctg
    18601 tttctcatat gaaagtcgaa cgtgattggc aaggaaatat cgttaaagag taatctttac
    18661 acaaaattta caaacttagc taaactttta catgttatta aaaccaaatt gatgttcaat
    18721 ttgtacactg agtgagtatg ttaaacctga ttaaggggga gtcatctgtg gaagatgtga
    18781 aaaaagtatt attaacaaaa tcaaaacgtt caaaaatgga acagcgtgga aaattcatca
    18841 gttttttatg tatcgcgctg atcgtgttgg ttgtattatc tattttttat tttgtagcta
    18901 gtaaaggatt ggccaccttt tttactgata agatcaatgt atttgatttt ctgtttggta
    18961 cagattggaa tccaagccaa atcggagcaa atgggaaacc aatggtaggg gcattgccta
    19021 tgatcacagg ttcgtttatt gtgacctttt tatctgctat tgttgccaca ccatttgcca
    19081 ttggtgcagc agtattcatg acggagatct ctcctaaaaa cggaacgaag atcttacagc
    19141 cggtcatcga gctgcttgta ggtattcctt ctgtcgttta tggttttatc ggtttatcag
    19201 ttatcgtgcc ttttgtcaga agtatttttg gcgggacagg gtttggtatc ttagctggta
    19261 catttgtgtt gttcgttatg atcttgccga ctgtcacaac gatgactgtt gatgcattaa
    19321 aggcagtacc acggcactat cgggaagctt cattagcgct tggtgccaca agatggcaaa
    19381 caatctacaa agtcgtgcta cgagcagccg tgcccgggat tttaacagca gtcgtttttg
    19441 gtatggctcg tgcgtttggt gaagccttag ctatccaaat ggtcatcggt aatgcagcat
    19501 tgatgccaac aggacttact actcctgctt ctacattgac gtccatctta acaatgggaa
    19561 tcggaaatac aatcatggga acagttgaaa ataatgtgtt atggtcatta gcgctgatct
    19621 tgctattgat gtcattattc tttaatatcg tgatccgtat gattgggaag aaaggagagc
    19681 tgaaataatg aacgcaaaac gctcagataa aattgctaca ggtgttttat atgtagtttc
    19741 ggggatcatc gtattgattt tagcagcttt actactttat atcttagttc ggggaatacc
    19801 gcacatttca tggtccttct tgaccgaacc ttccaaagcc taccaagaag gcggtggaat
    19861 cgggatccag ctatttaact cgatttattt gcttttgatc acgatgatca tcagttttcc
    19921 tatttcttta ggtgcgggta tctatctttc agaatatgct ggaaaaaact ggctgacaga
    19981 tgtgattcgc acgtcgattg aaatcttgag ctcattgcct tctgtcgttg tcggtttatt
    20041 cggtttcttg gttttcgtta ttcaattcca gtatggtttc tcgattattt ctggtgcatt
    20101 ggctttgact gtattcaact tgcctctttt gactagaaca gttgaggagt ctttacaagc
    20161 ggtccattac acacaacgag aagcaggatt ggctttaggt ttgtcacgct gggaaacagt
    20221 gataaaagtg gtggtttcag aagcgacacc agggattttg actggtgtga tcctaagttc
    20281 tggaagaatt tttggtgaag cagctgcatt gatctatacg gctggacaaa gtgcacctgc
    20341 gttagatttt acgaactgga atccattaag tgtttcaagc ccgatcagca ttttccgtca
    20401 agctgaaaca ttagctgtcc atatttggaa gatcaataca gaaggcacga tgcctgatgg
    20461 tgtttctgtt tcggctggcg cttctgccgt gttgatcatt gctgttttac tgttcaactt
    20521 cggcgctcgt gcgattggca aacgattata ccgaaaaatg acttcagcct aaggagaaga
    20581 agcaaaatga aaaaatataa ctggaatgaa acaaatgtca tcaccatgcc aaaagagaaa
    20641 gaagtagcac tatatacgga tgatctacat gtctggtatg gcgacaatga agcaatcaaa
    20701 ggagtggatc tggaatttga aaaaaataag atcactgcac tgattggtcc ttccggctgc
    20761 ggaaaatcta cgtatcttcg ttcgttgaat cgaatgaatg atgggatcgc taatacgaaa
    20821 atcactggga aaatcatgta tcaaggcgta gatattaatg cgcctcaagt ggatgtttat
    20881 gagatgcgca aacggattgg catggttttt caacgtccta atccgttcag caagtcgatt
    20941 tatgacaata ttacatttgc tttgaaacag cacggcgaaa aaaacaaaaa gaaattagat
    21001 gaaatcgttg aaacaagctt gaaacaagct gccttgtggg accaagtaaa agacagcttg
    21061 gacaaaagtg ccttggcttt atctggcggg caacagcaac gtttatgtat tgctcgtgcg
    21121 atcgcgatga aacctgatat cttgctgcta gacgagccgg caagtgcttt ggaccctatt
    21181 tcgacaggaa cggttgaaga aacacttgta aacttgaaag aagactatac gatcatcatc
    21241 gtgacgcata acatgcaaca agcggctcgt atcagcgact atactgcctt tttctatcta
    21301 ggaaaagtaa tggaatatga caaaactaac aagatattta ccagaccaaa aattcaggca
    21361 accgaagatt atgtgtccgg tcattttggt taagacggag gcctcaacat gacaaaagaa
    21421 attatttcat ctaaagatct tcatctgtat tatggaaaga aagaagcact aaaagggatc
    21481 gatctaagtt tcaatcaagg ggaaatcact gcgatgatcg gtccttctgg ttgcgggaaa
    21541 tccacttatc tgcgttcttt gaaccggatg aatgacctga ttccgaatgt aacgatcacc
    21601 gggagtgttt tatataaaga caaagacatc tatggtccaa aaacagatgt tgttgaacta
    21661 agaaaagaaa tcggcatggt attccagcag ccaaacccat ttcctttttc tatctatgaa
    21721 aatgtcatct atggattgaa attaaaaggg gaaaaaaata aaaaagtcct tgatcaagta
    21781 gttgaagaaa gcctgaaggc agcgtctgtt tgggatgatg tgaaagacaa attgcataaa
    21841 agtgctttat ctttatccgg tgggcagcag cagcgtgtat gtatcgcacg tgttttggca
    21901 gttaatccgg aaatcatctt attggatgaa ccaacaagtg cgcttgatcc tgtttctact
    21961 gggaaaatcg aaagtatgct gttagaatta agagagcggt atacgatgat catcgtgacc
    22021 cataatatgt ctcaagcttc acgtatttca gataagacgg cattcttttt agatggtcac
    22081 ttgatcgaat acaatgatac gaagaagata ttcatgaatc cagaaaaaca agagacagaa
    22141 gattatattt caggtcgatt tggataagga ggaaacggaa tgctacgtac acaatttgaa
    22201 gaagaattgc tgaatctcca taatcagttc tacgaaatgg ggatgatggt gagcagcgcc
    22261 gtgcacaagt cagttcgtgc atacatcaaa cacgataaaa tcttagccca agaagttatc
    22321 gaaaacgata taaatatcaa taacatggaa acacgcttgg agaagaaaag ttttgaaatg
    22381 atcgcattgc aacagccagt tacaactgat ttgcgtatga tcattacggt catgaaagct
    22441 agctcggatt tagaacgtat ggccgatcat gcggtgtctg ttgctaaatc cacgattcgc
    22501 gtaaaagggc agacgagaat accggaaatc gaaaaagaga tctccgatat gtccgattat
    22561 gtgaaaaaaa tggtggacaa cgtcctagtt gcttatgtca aaacagacga aaaagacgca
    22621 cgtacgatcg ccaatatgga tcaaagagtc aatgactatt tcaatcgaat ctataatgca
    22681 acaatcaaaa atatgcagga aaatcctgag acagtcatca gtggaacaga ctacttgaat
    22741 gttgccagtt atctagaacg gatcggagac tatgtgacaa acatctgtga atggatcgtc
    22801 tacttggcta cagggaaaat cactgagtta aatacgaacc acaatgagat tttctaaact
    22861 aaagcggtga ttctgccgtt tgtttaggaa aagaggttgt gaaatcagcg gttgtgaaaa
    22921 agctgttctg catcaagtaa taagaacagt caaacaaaaa tagctcctca tatttttcat
    22981 ttggctggac ttattaccgc agatgcaagc ttttgaacac tgtttattcg ggaaagggtt
    23041 tgtgacaaaa tatgtcacaa acccttttca tcatttcata gaaaggataa agaatgcaaa
    23101 aaaaaattag catcatcact atatttttta tttgtgtgct tacttcatgg gttattcagc
    23161 atcaagctgc tttatatgaa gtacctgtca tcgagatcga aaaagtacga ataaaagagg
    23221 atcatcaatt gattacagga agactgatga acacgaatca aaaaggagaa tcgatttatt
    23281 tatcggttcc ttatcaaaaa aatcaaatag aaacagcaaa tataaaagcg agacaaatgt
    23341 atctagtcca aatgcatgga gatgaatggc agctagtagc aaaaaaaaat gatggctggc
    23401 ttttcttctt cacaagtatc ttcattggcg ccatgttgct tattggcgga aaacatggtc
    23461 tatttgcttt aggaagtctc atcatcaata tcgttttact tttacttttg ttgctcatct
    23521 ttactaaaat agaagggatt tctctattaa atatatctat cctgttcgtc gttataggga
    23581 tgattattag catattggct ttagatggat ggaatagaag cagtataatc aaaatttcag
    23641 ctgcagttac gagtgttttt ttagcatttt ttatttgtct tttgacaatg aatctttgga
    23701 aagaccaagg actgcgctat gaggaactga attatctgac acgaccgtat cgttctgttt
    23761 ttctttctag cgtactgatt ggaacagctg gaggaacact cgataccgtt atcacagtca
    23821 ttgcgacatt agaagaattg actaagcgac aaccagaaat aacagcgaaa cagttatggc
    23881 tttcgggaag gcaagtgggt cgagatgtga ttggctcgat gaccaatatc cttttgttcg
    23941 tctatatcag tgggtcagtt ccatcgcttc ttttatattt aggaaatcaa tggtcgttca
    24001 aagaaacgat agaacagcat ttatcattgg aatttttacg cgtcattgct ggcagcttag
    24061 gaatagtatt atcgatccct atctcggtcc tcttttttct gactgtaagg aggctgaaac
    24121 gatgaatgta cttattatac ttgttgggat tttagcaatc agcgtgctac ttattggcgg
    24181 tacgcaaggt atgtatattc ttttaggctt attcatcaat ttagggatct ttttcttgtt
    24241 gttattcggt tatcatcaga agtggccgat actggcattg tcggtcatag gatttttatt
    24301 gattgctgtg gttatcttat tttttatcaa cggttataat ctaaaaatgc gtgcagcttt
    24361 tgtgagtata ctgatctttt tattttgttt cctactattg cttcctatca ctgatttttt
    24421 agcaatccaa ggttttacaa cgatagaact agaagaatta tctggcttag ataagacttt
    24481 agcgattgat tttagattac ttacgagatc gttgcttctg attagtctta gtggtgctgt
    24541 tttagatgcg agtgtagcaa tttctagtgg gacattcgaa gtatatcagg caaatccgca
    24601 attatctttt taccaattgc gccattctag tttcgctatt gctaaaaaaa tattggcgtc
    24661 aacagtaatg acacttcttt ttgcattcat gggaagttct ttagcgttga tcctctggtt
    24721 tattgattta gacattcctt ttcagcaagt gatcaatgaa aaatcatttg ttctagaata
    24781 tacgatggct attcttacca cattgtccgc actacttgtt cttcctttaa cctgcgtgac
    24841 tacagcatat ctctttacaa aaaagaaaga acaactcaag atggagtaaa agttacaact
    24901 taagtcctat gacattttta ctgaatcagt gcataatatg gatgtaagga aaagcttgca
    24961 aacaattttg cttaaggagg caatttccat gaaagaaaga gaacgtattt tagatttagt
    25021 gaaaaaagga atcctttcga ctgaagaagg cttagattta ttagaaagca tggcaactga
    25081 aaaagacgaa aagcaaatca aaaaagaagc agacaaggta actgctagtc ataaagaaaa
    25141 agatcaggca agtcaattga tcgataaact tgaaaacggc gaagaagaaa tttctgagcc
    25201 agttgatcca aaggaaagag aaagacaaga tcaagaaaac ttagaaaaga tcttagatga
    25261 actagcaact gaagcgaata aaacttcggc gcgtctagat gaagtaaatg ctcaattcgc
    25321 tgacaataag gcagcacgca atgagaaaca ggaagcattg atgcagctga atacaaaaga
    25381 agaattaggc gagttgacag aagaagaatt agcacagcgt cagacgttag aagcagaaat
    25441 caaagagtta gaagctagtg gcgatacact gttagaagaa caattgaaat tagaagcaga
    25501 attaaaagat atccgtaaga atcaatggtc tgagaaaaaa gaaacgttta ctgataagtt
    25561 tgaattgcca gatgattgga aagatcaagc aacagataca ctgaatcaag taggcgaaaa
    25621 aatgtcagaa gctggatcac agttaggaaa attcttgaag aaaacattcc aaactgtttc
    25681 agaaacagtg aatgacaaca tggaatggaa agatgtcagc ttgcgtgttc ctgggattgc
    25741 gacaacgaaa tttgagcatg aattttacta tgaagctcct gcagcaagta tccttgatat
    25801 caaggcagca aacggaaacg tgacgttaaa aacgtgggac agcaacgatg tgaaagttga
    25861 agctaagatc aaactttacg gaaaaatggg tgctgaacca tttgaagcat tctctgaacg
    25921 gagccagatt gaggttaatg aagatcatat ctccttccaa attccaaata aacgtgtgcg
    25981 tgcagacctt gttttctact tacctaaacg agtatacgac cacgcagcta ttaaacttct
    26041 aaatggcaac atcatgattg aaacattgga agctaaagat atttatacaa aatctacgaa
    26101 tggtaacatc atcgtggacc aattaactgc aacgatgctg gaagtagaag gtgtaaacgg
    26161 caatatcgat attcgaaacg ggaacatctt agattctatt atcgaaacag taaatggtac
    26221 agtgacattt ggtgcgacag cagaaaacct ttctgtgtct ttggtaaatg gtgatgtacg
    26281 tcttacgatt aaagaagata atttgaaaaa agtagaagca agttcagtga acggaaatgt
    26341 caaagtcgct ttaccagatg gcatcggttt ggaaggacat gctaaaacaa gtcttggaag
    26401 tatcaacagc cgtctgtcca attacgaagt agttcgtgag aaaaaagaac ggacaaacca
    26461 aatgttgcaa ttccgtcgtg tttcagatgg tgaaatcgcg caagtgcaac tttcaacgac
    26521 aacaggaagt atctatttaa aagatacaga taaataaaga ggttgtgaaa gagatgttca
    26581 gccttgagca ataagaagcg attttgtaaa atagcttccc ctattttaca aaattgtgcc
    26641 ttattgccga taggctatct cttgaacacc gtttaccaag agattatgaa cttgccaatt
    26701 atcgccgagt cacaaggaat aatttcaaaa aaagctcgtc acgttttatg aatatggtaa
    26761 tttgtgaccg agaattttgc aaaaagacac cgattaagaa gaaggttgtc acaacgattt
    26821 tcttcattta aaatagtaga acagaggtga gacatgatga aaaaaaagtt gacaaaatcc
    26881 aataaaaatg ttgttttgac agggacttta gcaggaatag gagaatacat cgggattgat
    26941 ccgactgtta tccgtgtgct ttatgtattc ctgagcttag ttgcttttgg aagtccaatc
    27001 attttataca ttttattagc tttgattatc ccatctgcgc gttctgcacg aacaaactat
    27061 ggacataaca atgcatatta tgaaaaaaac aattatcgtg aacaaactcg tgaacaaaca
    27121 aaaaaacgca aagaagcgga aaaaatcgat gatgacgaat ggagtgactt ttaatgtcgt
    27181 actttcaacg tattttagtt aatacgttaa cattcatatc attggctgtt ctttttcctg
    27241 cgatggtcca tgtgagcagt atttggacgg ccgttcttgc cagcttcgta ttgtctgtgt
    27301 tgaatatgtt tgtcaaaccg attttgacga tactgtccct gccctttaca ttagtcacat
    27361 tgggattgtt tacgtttgtt atcaatgcag cgattcttaa aatgacctcc ttttttgtgg
    27421 gagcagaaca ttttagtttt tcttcattcg gtgcagcgtt gttagtagct atcttgatgt
    27481 cgcttgtcaa tgtaattgtc agcgaacata acagtagaaa ataaaagaaa gctgtgccga
    27541 actatcggcg cagttttttt atttagaatc aggaatgcgt tttctattac attggtaatt
    27601 aaataaaaac gtttttttta attggtagta cttttggcta gacaatgata aaatgataga
    27661 gaacactcta atagaaatga ggtagcatga atgtcagaag ttgtaaaagt tagccaatta
    27721 gtgaaaaaat tatctttgga aatcgtgaca ggcgacgaga aaagcttaga ccgtgtcatc
    27781 gtaactgggg acatctcacg cccaggacta gagttgactg gttattttaa ttattattcc
    27841 cataatcgtt tacagctatt tggcagtaaa gaaatcagtt ttgcggaacg gatgatccca
    27901 gaagagcgtt tgatcatcat gagaagatta tgtagtgaag atatgcccgc atttattatt
    27961 tcaagaggat taccagctcc agaagaaatg atccaggcag caaatgaaaa tgggatagct
    28021 gtactgcgtt ctcccatctc aacttctcgc ttattaggag aattatccag ttatttagat
    28081 ggtcgccttg cccctcgaac aagtgtccac ggtgttttag tggatgttta cggattaggt
    28141 gtactgattc aaggtgacag tgggatagga aaaagtgaaa cagcgttgga gttgatcaaa
    28201 cgcggtcatc gattgatcgc agacgatcga gtagatgttt atcagcaaga tgaattaacg
    28261 gtgatcggag aaccgcctaa aatcctggaa catctgattg aaatccgagg aatcgggatc
    28321 attgatgtaa tgaatctttt tggtgcgagt gcggtacgtg gctctatgca agtccagttg
    28381 gctgtttatc tggaagcatg ggcaaaagat aagaaatacg accgtctggg ctctgaagac
    28441 acgaccgttg aaatcgcgga agtaggcatt ccacaaataa aaatccctgt caaaacagga
    28501 cgaaacgttg caatcatcat tgaagtagcc gcgatgaatt tccgtgcacg tacaatgggc
    28561 tttgacgcaa cgaaaacatt tgaagaaaga ttaagtcgct tgattgaaga aaactcaggc
    28621 aacgactagc aaggagtgac aatatgttag cacaaatcaa tcgagttgct tttgagcttg
    28681 tagggattcc tatctactgg tatgcattga tcatcgtatc aggtatcatt atcgccatgt
    28741 ggcttagcag cagagaggct gttcgggtag gattaaaagc agatgatgtg acagatttta
    28801 tgttgtgggg attgcctatc tccattattg gcgctcgctt atattatgtt ttatttgatc
    28861 ttccccagta tatagctgat ccaatccaaa tattcaatat ccgttcagga ggcttagcta
    28921 tttatggcgg actgattgca ggcgcgatca cgctgtattt ttttactaaa tatcatttta
    28981 tttctttgtg gactttttta gatatcgctg caccaagtgt attattagca caagcaatcg
    29041 gtcgttgggg aaatttcatg aaccacgaag catatggacc agacacgacg cgaagcttct
    29101 tagaaagtct gcatttaccg caattcatca ttgataatat gtatatcgaa gggatctatc
    29161 gtcaaccaac atttctttat gaatcacttt ggagtttgat tggatttatt ttgcttttgt
    29221 ttttacgaaa gaaaccacac cttttgaaaa aaggtgaagt ccttttatgt tatctaatgt
    29281 ggtatagttt cgggcgtttc tttattgaag gattacgtac agacagtctt tactttttag
    29341 gtgtgatccg tatttctcaa ttattatctg ctgtgttatt tgtcggtaca ttgattctat
    29401 ttatttggcg cagaaaaaaa ggaaatttac cggattatga ccgctcatta ggaaaaaatc
    29461 aacaaattat ctgattttta gagcgttaaa aatgaaaaaa atttcaggag tggtaaaatg
    29521 aattatagag tagcggtttt aggaccaggc tcttggggta ctgctttggc acaagtcctc
    29581 gccgaaaacg gacatgacgt tcggatttgg ggacatcgtg cttcacaagt agaagaaatc
    29641 aacacccaac acacgaatca acgttattta ccagatcatt gtctacccga ttccatccaa
    29701 gcattcacca atatggaaga tgcagtaaaa gacgcagatg cggtgctatt cgtcattcca
    29761 acgaaagcaa tacgttctgt tgcaaaagaa ctagtgccta aattgaatac aaagccagtg
    29821 atcatccatg caagtaaagg attagaacag gggacacata aaaggatctc tgatatcttg
    29881 ttagaggaaa tcccagtaga aaaaagaaaa gctgttgttg ttctttctgg accaagccat
    29941 gcagaagaag tagcgaaaca tgacatcact acgatcacag ctgcaagtac agatgcaaaa
    30001 gcagcaaaat atgtacaaga gctgttcatg aataattatt ttcggatcta taccaatcct
    30061 gatgtgatcg gtgtagagat gggggcagct ttgaaaaata ttattgctat tggtgctggc
    30121 gctattcacg gcttagggtt tggcgataat gcaaaggcag caatcatgac gcgcggatta
    30181 gctgagatca gccgtttagg tgtagcaatg ggtgccaacc cgctgacctt tatcggatta
    30241 agcggagtag gcgatctagt cgttacttgc acaagtgttc attctaggaa ctggcgcgca
    30301 ggcaacttgt taggacaagg gcagccccta gaagaggtgc tagccaatat gggaatggtc
    30361 gttgaaggtg tgaatactac ccaagcagcg atggaactag cccaaataat ggaaatcgaa
    30421 atgcccatca ctcaaacaat ctatgaagtg ctgtatgaac aaaaagaaat caaaacagcc
    30481 gcaaaagaaa tcatgttacg tgatgggaaa aaagaaaatg aattctcatt aacaattttt
    30541 tgaaggagcg aatgtatatg aaagtcaaaa aagcagttat tccagcagca ggattaggaa
    30601 caagattttt accagcaaca aaagctatgg caaaggaaat gttgccaatt gttgataaac
    30661 caacaatcca gttcatcgtt gaagaagcgt tgaaatcagg tatcgaagac atcttgatcg
    30721 ttacaggaaa agctaaacga ccaatcgaag atcactttga ttcaaatatt gaattagaaa
    30781 caaacctaag tgaaaaagga aagaccgaat tattgaaatt agtagaagaa acgacagatg
    30841 tcaacttgca tttcatccgt caatctcatc caaagggttt aggacatgcc gttcttcaag
    30901 caagagcctt tattggaaat gaaccatttg tcgttatgct aggcgatgat ataatggaag
    30961 acgaagtacc attgacacag caattaatcg atgattacga acgtactcat gcttctacga
    31021 tcgccgttat gcaagttcct catgatgaaa cttcaaaata cggaattatc aatccaggag
    31081 aagtattgga agatgggtta tacaatgtca aaaactttgt tgaaaaacca gatccaagca
    31141 aagcaccaag tgatttagct attattggac gttacttatt gactccagaa atttttgatg
    31201 tattgtccga gcaacaacca ggagccggaa atgaaatcca actaactgac gcaatcgata
    31261 cattgaataa aacacaacgc gtatttgccc gtaaattcac aggtaaacgt tacgatgtcg
    31321 gtgacaaatt tggttttatg aaaacaagta ttgaatatgg tctaacacat ccagaagtag
    31381 gtgcaccttt acgtgagtac atcctgtctt taggtaaaac attagaagca gaaggaagca
    31441 agatcgatca taatccaaaa ggaataacag aaatcaaaga agaaaagaaa aaataaccct
    31501 tttttctaac gagcttcagc tgctaattga ataaaaagta gttgaagctc gtttttattt
    31561 gtttaaaaaa cacgaaaatg ctatccttat agaaaagaga gacaagaagg gagtttgatc
    31621 atgtcaggag gagaaattgc aggattgatc gcagcaatcg cctttgcgat acttgtcgtt
    31681 tttatcgttc gtgtgttgtt gaaagtttct aaaactttag aaaaagtaga tcagactgta
    31741 gcagaagcaa atacgacgat cgaaatcgtc acaaaagacg tagatctttt gtctagacaa
    31801 gtagaaggct tactggtcaa aagtaatgaa ctgctcttgg atatcaatgg aaaagtcgca
    31861 acgatcgatc cattgttcac agcagttgct gatttaagtg aaagtgtatc agaacttaat
    31921 cattctagta aaaacatcgc gacgaaagtc ggcggaatcg gtaaaacgac agctaaagcg
    31981 acggttgccg gaaaagtcgg tgggacagcg atgaaatttt ttaaaaacaa aaaacatact
    32041 gaaacgacag gaggaaaata aaaatggcta aaaaaggtgg atttttatta ggtgcagtag
    32101 tcggaggcac agccgcagca atcgccgcgt tattgttagc accaaaatct ggtaaagaac
    32161 ttcgggatga attagctgcc caagcggatg atttgatgga tatggcttca gattacacag
    32221 atatggcgaa agaaaaatcg actgagttaa caggtattgc aaaagaaaaa gcgcaagatc
    32281 tttctcaaca agcaggtgat ctagcaggta gtgtcaaaca aaaagtaagt gaatcagcag
    32341 atgaagcagg aagtgaatct gacgatatct tgttaaatct taaagaacaa tcagctgact
    32401 tatctaatcg tttcaaaaaa acggcagaag atatgaaaaa acctgcagat gaattaggaa
    32461 gtattgctaa agatacttca gaagatatca tgattgatgt aaaagacgct gctggtaaag
    32521 caggagatac tgtcaatgaa ggaatgtcag aagcaaaacc agttgcagat gactcaaaag
    32581 aaatgatgaa aatggcaaaa gaagatgcga aagaagctaa aaaagaaata aaagatacaa
    32641 tgacagattc atctacaaat cactaaaatc acaaatttat agaataaaaa ggtgggagcg
    32701 gactagctct cacctttttt actcttattt ttctaaaaca agtaattctt ttggtgtagt
    32761 cgtgaatggc acacagccat cgcttgtcac atatacacag tcttcgatac gtacccctac
    32821 tttttcagga atatagattc ctggttcaag agagaagcac atcccttctt cgattactaa
    32881 gtcatttcct tctacaaggg aagggaattc gtggacggtt gttccgatcc cgtgacctaa
    32941 acggtgattg aaatattcgc cgtagccata gctgttgatc acgtttcgtg cgatttgatc
    33001 aagttcacct gctgtcacac ctggacggac ggcttcttgt gcggcaagct gtgcttcaag
    33061 agtgatgttg tagatttttt cttggaagtc ggttggtttt tgataagcaa ttgtacgagt
    33121 agcatcactg caatagccat tccaaacaac gccaagatcg aataacacaa gttcattcgg
    33181 tgaaatcttc gtatttcctg gtgtaccatg agggcttgca gcatttgctc ctgcaaggac
    33241 taatgtgtcg aaagacattt gtgaaacacc ttgttttttc aattggtatt caatttctgc
    33301 aatgatcgct tgttcagtca cgccttcttt cactgcttta aagccaatct caaatgcaac
    33361 atcggcccat ttaccagctt cgatcagttt gtctttttcc tctagagttt tgatcagttg
    33421 tagacgttgg atgatggaag ttagatcagt gtaagaatcc gttcccgtca agatatcaga
    33481 gatagcatcg aagcgctcga cagtcaaggc gttcttttca atccctacat tgccaggctg
    33541 accatagcga gcacgaagtt cttttccgat gatctcccaa gggttttcgc tgtctaaata
    33601 gccacggaca tcatacgccc aactactgtt ttgagcatct tcaacttcca aagcaggagt
    33661 gaaaaggaaa ggatcttgtt caagagggat aaaaagagct agtacacgct catgaggatc
    33721 actttcgtat ccggaaaagt aagcgatgtg gccagggtcg ctgatataag ccaattcgac
    33781 ttggtgttgt gccatccatt gacgtagttc attgattttt acgttattca tttggcaacc
    33841 tactttctaa attaattttg tattcaataa ttgtaccact gatttattaa aagaccaacg
    33901 ttctaaaaac tgaaaaaagt aaaaattttc atgaaaacag agataaaacg gttgcaattc
    33961 ttgagattat ttgatattct attttagaaa tgtaagacgt attttcagaa aacatataaa
    34021 atatgaatag gagaacacaa atggaaaagc aaacaatcac tatctatgat gtagcgagag
    34081 aggcaaatgt ttcgatggct actgtttcac gtgtcgtaaa tggcaatcca aacgttaaac
    34141 cagcaacaag aaaaaaagtc ttggaagtta tcgatcgctt ggattatcgt ccaaacgcag
    34201 ttgcgcgtgg cttggcaagt aagaaaacaa caacagttgg tgtaatcatc cctgatgtca
    34261 gcaatatgtt ctttgcttct ttagcacgtg gtatcgatga tgtggcaaca atgtacaaat
    34321 acaatattat cttagcaaat tcagatggca acgaccaaaa agaagtcaat gtattgaata
    34381 acttactggc taagcaagtg gacggcgtga tcttcatggg tcaccatatc acagacgaaa
    34441 tccgtggaga attttcacgt tcaaaaactc ctgttgtatt agctggctct attgatccag
    34501 atgaacaagt aggtagcgta aacattgatt atgtatccgc aacaaaagat gcagtaaaca
    34561 aattggcaaa aagcggcaat aaaaaaatcg cttttgtcag tggtgcgttg atcgatccca
    34621 tcaatggaca aaatcgtctg aaaggctata aagaagcatt aagcgaaaat aacctaccat
    34681 atagcgaagg attgatcttt gaagcacaat acaacttcaa agatggtcta tctctagtcg
    34741 atcggatcca taatagcggt gcaacagctg tctatgtttc agatgatgaa ttagccatcg
    34801 gtattttgga tggtttatta gaccgtggcg tgaaagtacc ggaagaattc gaaatcatca
    34861 caagtaacaa ttcactactg acagaagtag ctcgtcctcg tttaacaagt atcacacaac
    34921 cattatacga tttaggggct gtatctatgc gcctattgac gaaaatgatg aataaagaag
    34981 aagtcgaaga aaaaacgatt atcttgcctt atggaatcga agaaaaagga tctacaaaat
    35041 aataaaagga caaccattca gaggttgtgt gcctgccgtt taactctgcg ttacaaggag
    35101 caatttcaaa aaacagcatc tcatgtttga tgaatattgt gactcgtgat tcggagttgg
    35161 caggagaaca ccgtttattt gggaaaaggg gttatgacaa aattttgtta taatcctttt
    35221 tttgtgtctt aaaaaagaga gaaagtggtt gaaattacat ttatcgtata taaaacaatc
    35281 cgtgtataga tgctgcattt tgttcaccac catcaaaaaa ataagggact gtgacaatac
    35341 tattgtcaca atcccttatt actgtgtatt ctattaaatc aatcatcttt ctcatctgat
    35401 tctttagttg cttgattcgc tcttgcataa gctgaagcgg tgttccagta atctgtatag
    35461 ttttcatcgg taccgccaac gccaaattta aaggcgcttt tcttcggtcc atttttcgcc
    35521 catagcgatt caactgtttt tcctggtgtt tggatggatt ttttattgac agtaactttt
    35581 ccaggtgttt gaccagtaaa tccagatact tttttcttca tcacatcaga tgataattcg
    35641 aatttctcat cagtgccaaa aatgtcaggt tttgcttggt aagcttgatt gatcagattg
    35701 gcaagataat tagccgaacg tatccttgct ttgctgtcca ttccagtatt gtcatcgtgc
    35761 cctgcccagc tactgatggt aatagacgga gtagagacaa ttagccatga atctcggtat
    35821 tcattggtag aaccagtttt tccgacccaa tctgcttttc ctagatttcc gtttaagctt
    35881 gagatggcat ctttgaatgg tgtagtgatt tttgcattga tcacactacg catcatgtca
    35941 ttcatgatcg atgccgttgc ttccgaatag atccggacag agttgctttc gtgtttataa
    36001 attacatttc ctgcgttatc tgtgatggaa tcgatgatat agccttcttc atagacgccg
    36061 ccgtttgcta aagcctgaaa tccgttggtc tgttgaagcg tcgtgacatc tactgtacct
    36121 aaaggagcag attcaacgcc ccaattgtca tttgccgggt agttcatctt tgccaagtag
    36181 tgctcgtaag catattgttt cgatccaccg gaattcaaca catcttgata taagtgataa
    36241 gccgggatat tgttggacca ttctagtgac tcacggacgg tttggaaggt gttcgatcct
    36301 tcgttagtag cattgacgat tttctcgcca gcattttctc cttcttgcca agttgttgca
    36361 taatctgata cacgggattc tgatccgata agccccatgt cgattgcagg tccataaaca
    36421 agaactggtt tgattgatga gccagcttga cgttctgtat cgaaggcatg gttattttga
    36481 ttctgactgt aattccgtcc gccaacgaat ccgtagatgc ggccagttct gttatccatc
    36541 aatacatttc cggtttctac ttgactgcca gcaccatcat ctaacatgta tccataattt
    36601 tcaacgccat tttgcaatgc agcatagaca tctttatcga ttgtcgaatg gattgtatat
    36661 cctttatttt ggatcgtttg ctgtgccttt tgataataag cgtcactgac cgatgaatca
    36721 gacatatcag cgttgtcttt ttcagccaat tgttgtgcaa tgattcttgt tgcttcattc
    36781 atcacagtat aatacaagaa ttctctgtca gtctgttctg cgatttgttg tggtagaaag
    36841 tcttttgtaa ggtcataggc ttttgcttct tcgtattgtt ctttcgtaat ttggccttca
    36901 cgatacatac tgaataaaac aaaatctttt ctggcaaggc cggcagaaag atcttctttt
    36961 agcgcgcctg tgttcgtgta tggactatac gtgatcgggc tttggggtaa tccagcgata
    37021 taagcagctt gcggcagcgt cacatctttt gcatctacac caaagattcc ttttgcagct
    37081 tcctggactc cagcaatgtt ttgtccctta ttattacgac caaatggtga gacattcaaa
    37141 tacgtagcaa tgatctcatc ttttgaaaag tatttttcta cttgtgcaga aagaatgatc
    37201 tcgtttgctt tacgtttgaa tgttgtttca tctgtaagga tctgctgttt gactaattgc
    37261 tgtgtcaaag ttgatccacc agaagagcca ataccagtag cttcagatac taatgctcgt
    37321 aaaacagctt taggaacgta accttggtgt ttatcgaagt attcatcctc tgtgctgata
    37381 attgcagttt tcaataaagg tgaaatctta tcagatgaaa tagtcgtgcg catcagatct
    37441 gtctggattt ttgatatctc tgtattatct gcataaacaa tctttgacgt ttctgtaatg
    37501 tttcctagtt ctgtctgcag tgctttttta gtcggcaatt gtgtgtcttc gacgagatag
    37561 gcaaaatagc cagcgcctat tccaatacct agagctgcga acatcaaaag aagaacagta
    37621 ataaaaacag tcaatgattg aaaaactcta aaaataatct taggaacaaa ccatttttct
    37681 ttttttcttc tattctgttt ttttcgagta tttttgcgtg gcaaaagggt cacctcaact
    37741 aatggtttta tttcgctaat tatagcaaat aatagaacaa aaaaacagac aaggctgttt
    37801 ttggcaggaa tttctttttt aaaagagtta aaacgtgaga aaatgatctt tattataaaa
    37861 gagttcttaa gcttttcttt agagaaaatt tcagttacta tggagaacag ggcaaagaaa
    37921 aatcaatcat tttctttgta tatcatctta ccaatatata ggaattgtta gtaacaattg
    37981 cctttcaagg aggaatccat ccatgttatt aggctcacac gtcagcatga gcggaaagaa
    38041 aatgctgtta ggagcagcag aagaagcagc cagttatgga tcttcgactt ttatgatcta
    38101 tacaggcgcc cctcaaaaca ctagaagaaa agccatcgaa gagatgaata ttgatgccgg
    38161 aaaagcgtac atggcagaaa aaggtctaac aaatatcgtc gttcatgccc cttatatcat
    38221 taatttgggg aatacgatca aaccagaaat gtttcctttt gccgtccaat ttctgagaga
    38281 agagattgtt cgtgcggaag ctttaggcgc tactcaaatt acacttcacc caggtgctca
    38341 tgtaggggca ggaacagaag ccggaattgc tagaattatt gaaggcttga atgaagtttt
    38401 gacaaaagaa cagacggcac aaatcgcttt ggagacaatg gcaggtaaag gtacggaaat
    38461 cggtcgaaca tttgaggaat tagcgcaaat catcgatgga gtaaaattga atgaaaaatt
    38521 atccgttact tttgacacct gtcatacgaa tgatgccggt tataatatta aagaagactt
    38581 ttcaggtgta atggaagagt ttgataagat catcgggtta gatcggctta aagtactcca
    38641 tatcaatgat tctaaaaatc cgcaaggttc gcataaagac cggcacgcca atattggttt
    38701 tggaacaatc ggattcgaca cgctgaataa gatcgtccat gatccaatgt ttgacaatat
    38761 ttcgaaaatc ttggaaactc cctatgtagg caaagataaa aagaaagctt acgcaccata
    38821 tggaaaagaa atcgccatgt tcaaagcgca aacattcgat ccagaagtgt ttcctgagtt
    38881 attagcagaa gaagtgatac tctaagattt tctatctgac agcagcaaaa aaggaccagg
    38941 cacattgcct tgtccttttt tgtttaagaa acaaaggagt actttttgca gtctttttca
    39001 tcatgcatct tct
//
LOCUS       DACGMI010000025        37964 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.026, whole genome shotgun sequence.
ACCESSION   DACGMI010000025 DACGMI010000000
VERSION     DACGMI010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37964
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.026"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(193..1503)
                     /locus_tag="IXT46_001407"
     CDS             complement(193..1503)
                     /locus_tag="IXT46_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAQ4947328.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1515..2933)
                     /locus_tag="IXT46_001408"
     CDS             complement(1515..2933)
                     /locus_tag="IXT46_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4947329.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3173..4741)
                     /locus_tag="IXT46_001409"
     CDS             complement(3173..4741)
                     /locus_tag="IXT46_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAQ4947330.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHYLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4745..5155)
                     /locus_tag="IXT46_001410"
     CDS             complement(4745..5155)
                     /locus_tag="IXT46_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAQ4947331.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFVAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5152..6063)
                     /locus_tag="IXT46_001411"
     CDS             complement(5152..6063)
                     /locus_tag="IXT46_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAQ4947332.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPKVLIVKEGRY
                     DEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVLENLH
                     IENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFCTPAS
                     ANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKNQKTG
                     YRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNEQTVK
                     FSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6060..6938)
                     /locus_tag="IXT46_001412"
     CDS             complement(6060..6938)
                     /locus_tag="IXT46_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAQ4947333.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6925..8262)
                     /locus_tag="IXT46_001413"
     CDS             complement(6925..8262)
                     /locus_tag="IXT46_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAQ4947334.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMRRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8265..9368)
                     /locus_tag="IXT46_001414"
     CDS             complement(8265..9368)
                     /locus_tag="IXT46_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAQ4947335.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9442..10950)
                     /locus_tag="IXT46_001415"
     CDS             complement(9442..10950)
                     /locus_tag="IXT46_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4947336.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10916..11608)
                     /locus_tag="IXT46_001416"
     CDS             complement(10916..11608)
                     /locus_tag="IXT46_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAQ4947337.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11630..12604)
                     /locus_tag="IXT46_001417"
     CDS             complement(11630..12604)
                     /locus_tag="IXT46_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4947338.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12904..13776
                     /locus_tag="IXT46_001418"
     CDS             12904..13776
                     /locus_tag="IXT46_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4947339.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14358..16556)
                     /locus_tag="IXT46_001419"
     CDS             complement(14358..16556)
                     /locus_tag="IXT46_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4947340.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16788..17780
                     /locus_tag="IXT46_001420"
     CDS             16788..17780
                     /locus_tag="IXT46_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4947341.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17840..19261
                     /locus_tag="IXT46_001421"
     CDS             17840..19261
                     /locus_tag="IXT46_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAQ4947342.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19254..20753
                     /locus_tag="IXT46_001422"
     CDS             19254..20753
                     /locus_tag="IXT46_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAQ4947343.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20792..22186
                     /gene="uxaC"
                     /locus_tag="IXT46_001423"
     CDS             20792..22186
                     /gene="uxaC"
                     /locus_tag="IXT46_001423"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAQ4947344.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22345..23028
                     /locus_tag="IXT46_001424"
     CDS             22345..23028
                     /locus_tag="IXT46_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAQ4947345.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELSQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23030..23866
                     /locus_tag="IXT46_001425"
     CDS             23030..23866
                     /locus_tag="IXT46_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4947346.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23877..25631
                     /locus_tag="IXT46_001426"
     CDS             23877..25631
                     /locus_tag="IXT46_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947347.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFMTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25907..26248)
                     /locus_tag="IXT46_001427"
     CDS             complement(25907..26248)
                     /locus_tag="IXT46_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAQ4947348.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26316..28487)
                     /locus_tag="IXT46_001428"
     CDS             complement(26316..28487)
                     /locus_tag="IXT46_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAQ4947349.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28698..29555
                     /locus_tag="IXT46_001429"
     CDS             28698..29555
                     /locus_tag="IXT46_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAQ4947350.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29626..30483)
                     /locus_tag="IXT46_001430"
     CDS             complement(29626..30483)
                     /locus_tag="IXT46_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4947351.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30468..33170)
                     /locus_tag="IXT46_001431"
     CDS             complement(30468..33170)
                     /locus_tag="IXT46_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAQ4947352.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33183..34472)
                     /locus_tag="IXT46_001432"
     CDS             complement(33183..34472)
                     /locus_tag="IXT46_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAQ4947353.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34622..35668
                     /locus_tag="IXT46_001433"
     CDS             34622..35668
                     /locus_tag="IXT46_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4947354.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35670..37823
                     /locus_tag="IXT46_001434"
     CDS             35670..37823
                     /locus_tag="IXT46_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAQ4947355.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
BASE COUNT        11219 a         7821 c         6748 g        12176 t
ORIGIN      
        1 cgatagaatc aagcttcgca agtggttctt tttaacgact tagttatctt atcacgtcta
       61 aaaacatgtg tcaactcttt tttggaattt tcataaaatg tttcaatgaa gcgcgacaac
      121 gttgtttaat atatcattaa aaaaaataaa ggtcaagcta aaatattatt taagcttgac
      181 cttattataa tttcaacgat tgtcaaaagt attgtttgca gctgtgttgc cagtttctat
      241 agataaatca cagcttttga aacataagtt ttgtactgct tcgattcgcc cgaattcttt
      301 tgcagttatt tggcaatgag aaaagcagac atcttctata ggcttttcag gaaatgctac
      361 taaatcaaaa gctcgggaag gaagtgagta acctggagaa aggcatgcct gtacgttttt
      421 gatgtgtatg tctttgactt tcgtcatttg ctttgattca ggtatttctt cagccactgc
      481 ttgccaactt tctggcattt gagcaaggtc attgctattt tttctattgt attcattatg
      541 ccagtccatt atccaagaaa aaggaaattg tacatcaatc atattcagat tttctaccct
      601 gatattttcg atcactcccc ctctttcttt tgaagatttc attcgaatac cacagtctga
      661 ctgaaaaaaa tcgatatcgt gaatatatac gtcactaact ccagcactaa cttcgctacc
      721 aatagttaca ccgtatcctg aacggatttt acatctagca acctcgattc ttgatgattt
      781 tcgattgact cttgcaccat tgccatctct gccagactta atagcaatac aatcatcacc
      841 acaggccaaa tcacattcat agacacgcac atttgttgaa gaatcaatat caatcccatc
      901 tgtacttggt ccatcattgt tgcggatgat tactttttct actaatacat cgttagaata
      961 agtgatttgc aagttccaaa aacctgattt ctgaaaaatc aaatcacgaa caacaacatg
     1021 ttctgcatga tacagtaaac aagcgcgtgg acgtttaata gcataatccg caatccaacg
     1081 aagtcccttt tgatcgtatt cagctcttgt cccgcttttt tgatcttttc cccaatacag
     1141 ctcccaccaa tggtctcctt gaccgtcgat tattcctttt ccttctataa gaatatcttt
     1201 cgccgagaga acattcaaaa tcgctgctgg ccatttcatt tctacgccgg ctactcgtgt
     1261 atcgatttct ggaaatgctt cgatatctgt tctccccttg aggactgcac cttcttcaaa
     1321 gataagatga ctcttatctt ttaaaaaaag ggctccgact aaataaatgc cttttggaat
     1381 aaatacaggt aagtgttctt tcgcaccttg atcgattgct ttttgcagta ttattgtatc
     1441 atcttgttga gtgtcgtttg ttttaaagtt caaagcattg ataatccctt tttttgtccg
     1501 caatacgttt ctccctatct ttcattgatt tttttcaatt cttcaccaat aaatacagtt
     1561 tttgaacgat tcagtgggta acctactagc aaaatgattg cggatacaaa taagcagaat
     1621 gctggtaaca agtttgccat cgtataaatc ctttcttgta ctaaaactga ttggatggct
     1681 ccacctgttg tagacgattg gtaaccaatg agtgccagca taaatccgcc taccgctcct
     1741 gcacatgctt gtcctacttt tctcgcaaaa gaatttactc catatactgt tccatcttct
     1801 cttaagcctg tcttatattg atgataatca atcacgtcag taatgaatgc ccagaccatc
     1861 aaattgaata aaccagatcc taaagtagcg ataaataaaa gaatcagata tacccatgca
     1921 tttgttatat gaaggaaata catcagcaag tacatacatg aagaagcaag taacgcaaat
     1981 acgcttgctt cctttttgcc aaataatttt gtcagctttg tagcaaatgg tgctaaaact
     2041 actactgttc cgtaagtaaa taaaagagca acagacattg cttgtttatt atggaagtaa
     2101 tcattgaata aataagtcat attcgtccca gctaaaatct gattgatcac aatgaaaatg
     2161 tcaacaatga ctaaaataat cagtgctcga ttagctaaca aaccttttac caactgagaa
     2221 gcagatactt tttcgttttt gacaactctt actctttcag tagtcaattt acaagttaac
     2281 atatatgcga caaatgctat tgcagcacat ccgattgaaa tccaaaagaa atgattccct
     2341 gaaacgactt gttgtccact cttgttatgg gtatacatta aaatcggaat gaagaatcct
     2401 gtagttgatc cgccaatcgc agaaccaatg cttcggaacg tggacaacga ggtgcggtca
     2461 ttaggatttg agctaattgc tgctgccatt gctccatacg ggatattgat tgttgagaga
     2521 aaaatcccat aaacaatgta tgaaacaaaa atataagcaa tcttcaccgt cattggaaga
     2581 tgttggacga atggcaaaaa caaaatgaca gtcactaagc aaaatggata cttcattttt
     2641 ctgatccaag gaataaatcg gccagtttct gttaactctg agacatcaca taatcttcca
     2701 accatcacat cagcaaacgc atccaaaatt ctcgaaatca agaataacgt acctacgatt
     2761 gcccctgaaa cgccaagaac attcgtataa taaatcatca agaaactatt gactaaacct
     2821 aaaataaaac agttacctag atcaccgaac atgtagccta tcttatcgga aatcccaaat
     2881 tccttttttt ctttttttac tgtatttgct gtaacagcat tttgtgaaag catttgaatt
     2941 cctcctacct cttctagtaa acgttttcaa aattataact ctttttttct tgtttttata
     3001 ttcacaatgt tggcttttta ttgcattatc ttgacagata aaaaacaaaa aataatctaa
     3061 aaacattgat gcataagatt gataactttt tttacataac aatatataca aacaaaaaaa
     3121 ttcactaact agtgaaaata agttagtgaa cctcatttat taaagaatta aattacagat
     3181 gatcttttcc atcatacttg aaaaactcaa aatcagcata acttcctctt tttttattta
     3241 gatcatgcac tgctatcccg ataaaatttc cagtaaaccc tcctgagagt atacacatgt
     3301 ttttttgcgg acctactttc ttccattctt cagttgatac gtctttcaaa tgaaactgtg
     3361 ctgtctcttt ctttacagtg actttcaaaa aagtcttctt ttctgtgagt ggaatcgtcc
     3421 aatcttctat ttgtgctact ccgttttctg attctatcat acgtaggcat tttcccttgt
     3481 cctcattcca agtaacataa caataaatat aattggattc atttaagtac agtaccagtc
     3541 cagccatctg attaaaatta ttaggcatgt attcaaatgc tgtctccgca tcaaaagtaa
     3601 aatccgtttg ccgaatagct aacaaatgat gttcgaaggt agattgaaga gattcaccgg
     3661 aaatcagacg taaaaaacct ggtctacatt ttgtatcaca ccaatcagca tttggcaaaa
     3721 tgcgtctggc attccagttc ttctttagct ctccttcaaa tgtatccata aactgatgat
     3781 ctttttcttg ttgtacctct tcatttgtct caatcattat ttcttccatc ggagttgtct
     3841 ggctatcttt aagtcttaac caatcgtcgg acgtccaata cacttcttga atagcggttt
     3901 ctcttcccaa aatagccgca ccgtttaatg gtctggtaca aagatatgtc atgtaccatc
     3961 ttcctgacgg ggtttgtact aagctcccat gtcctgtaca ttgcaatgta gaagcaggtt
     4021 tgtcactagc tgtcagcata ggaaaaccag gatcaagctc gtaaggacca gtaatattct
     4081 ttgctcggca aactgtaact gaatgtcctc ttcctgtacc gccttctgcc gtcatcaaat
     4141 aataataccc gttacgaaaa tacaaatgtg gtgcctccgt tttcgctaat tctgtacctg
     4201 caaatatttt atagatggga ccatcaagct tcttcttctc tgcatcatat tcttgtaata
     4261 cgataccgct ggatttattc ggtgtgtcca gacgataatc ccatagttca ttgacaagcc
     4321 atttttttcc cgtttcaaga taatggaaca aagaaggatc aaagccgtta ctatttaaat
     4381 aaattggttc ggaccaagga cctgtgatct cagatgcagt gatcaaataa ttgtggacat
     4441 ctttaaacgg acggcctgca cttttgacat ctgtgtaaac aagataaaac aatccatcag
     4501 cataactgat ctgtggcgcc catatacttc catttgtagg atttccttgc aaagatactt
     4561 gagtggtcaa aatatccgtt gtatgtgacc agttgactaa atttttcgac tcatatactc
     4621 ggattcctgg aagccattca aaagaggaga caataatgta ataccgctct ttcactctta
     4681 atatattagg atctggattg aatcctctta aaataggatt tttcactttg atagtctgca
     4741 tgattcaggc tccttttctc attcttactc gatataaact gaatgcccca gctgcgaaat
     4801 aaaaaaatgc aaaaggaaac gcaacaaact gagtgccaat caacaatatg aatcctgtta
     4861 taaaatacaa accagtggca gttgttaagt attttccttt agcagtcaaa aacaatgcta
     4921 ctgctaaaaa agcaagtgaa ataaacaaca caacggcaaa cagaccagtc atgtcctgta
     4981 ataatccaaa tgtattttct aaagacaaag ttgaatgatc tacagcaagc gactgataac
     5041 tttttttaaa ctctgacgca gacatattac ttaaagtaac tgctaacccg ccaaagaaaa
     5101 tcaaagatag actgccaccg accattccta gcaatagttc ccattttctt ttcatttctg
     5161 aaccccctgc ttttctaaat gtatccattc aggtcttttg atcgatgttt cataattgtt
     5221 attacgttca gagaatttga cagtctgttc atttttcttg tcatcccaat tatcccaacc
     5281 agttgggtga acatgcccac ctatcttaca cgcttcaaat aagacatttg catacggacg
     5341 ccacggtctt cctaaataga cgtttctagt atcaggttct gcagtcaagg tacagctttc
     5401 aaaacgatac cctgtttttt gatttttcgg cgtagatgct gctgtgatgt atccaggatt
     5461 tttactggct aagctatgga tatgacactg atgaaaaacg gcatctgccc caccaaatat
     5521 gaaatccacc gttccttcaa tccagcaata ttcataggtc tgacgacaat actcaggatt
     5581 ggcagaagcc ggtgtacaaa aaggagtacc atctttttgc aaatcaggca acggacccgt
     5641 gcataaggta tcctgataac cagatagtcg acagtttttt aaagatacgc gatctcctga
     5701 attgaataaa gcaacagcct gtcctacctt ttctcctgga cctgctgtat tttcgatgtg
     5761 aagattttct aatacgacat tcgatccttc taagaaaaaa gtagcacttc ggaaagtccc
     5821 taactggcta ccgtcaagat actcctgttt tgcaaaacga ttaccggaga taactactgt
     5881 tcctgctccc acaagtttaa aattggataa tctgctttct atatattcat catatcttcc
     5941 ttcttttact atcaagacct ttggcaggcc tgccaaataa tcgattcctt cttggatagt
     6001 ttcaaaatcc gtcggggtat ctatagcatt ctttccaatt atcagtttgt ctttcatcct
     6061 cataaatgct cccttatgaa ttgtttccaa atatttctca tttcttgtgt ttccatatga
     6121 ccgcctgtta aagaaaaaga agaaaagttt tctggactac ccattgattg atactttttg
     6181 tccagccctt ttctcagctt cagtacgcct tcgtccaagc acatcgtatc gttttttcca
     6241 actaagctaa gacgagggcg cggagcgatt ttttcttgga ttgctaacgt tgtataagct
     6301 gtcaatagat ttggcacata gtaataaaac ccatgatgat ctaggcggcg atgtagcaaa
     6361 agtgtttcga tgtccacctg tgccgctaga tcaatacaaa ctttgacacg agaatccaat
     6421 gctgtcaccc accagcttaa taagcctccc atagaaagac caatcgttgc gagccgttga
     6481 gtatctgtgt cttcccttgt ctccaaataa tcgatcaagc tgatcacatc ataaatacgc
     6541 attccccata acgtttttcc tgttaataaa aattgtttga acaactcgct ttcagaaata
     6601 cctccgcgtt cttcaaatcc ccaagcatca atcgaccaaa cagcatatcc cattcctgtc
     6661 agtacttctg caaaagatgg agaagctaag taaggagcac catggatcaa ttcacttttc
     6721 ccgactgaaa aatctccgcc gtgagaatgc aggtaaagga ccgtcggaaa cggtccttct
     6781 ttttctggat aagcatagag ggctggtact gtttccaatt catttaagta caattgatag
     6841 tattcaagca taaaaccgtt ttgtttttct cggtataatc gttttccact aggggtatgt
     6901 ctgctagatg gagcacctaa aaaatcattc aactgcataa gcaaagtttt tacgaacaac
     6961 cagttcatcc atattttctg attgatttga ttggaatttc tcaatactga tttctttagt
     7021 attttctaat agaaatgctg gtccctcgtg attttcaatc gacatctggt taaaggaaac
     7081 cttacccgca aagccaatat aaaatccttg tcttctcatt tcctctattc ctgtcatcat
     7141 agcaggaaca ccgggaactg catcttgggc catcgagaca tcgatattgt caaatgtgat
     7201 ttcttgtatg aattgttccg ctaatccata aataaaacct gcagaagcat ggacattcct
     7261 tgccgtgata ttcgaaaaat ggatccttct gaatgctggt gtccgttcat ctatcggata
     7321 agcctttttt tcccatacat acggttcttt ccctcgcgga ccacagaaat aataaagatt
     7381 cagtataaat ggacacatca cattatccat gactatattg gatactcgaa tatcttcaac
     7441 gatcccgcct cgacctcgtc tagatttcaa tcgtattcct cgatcagttt cttggaagat
     7501 acaatttgaa atggtaatat tacgaatact accactcatt tcacttccta atacgacacc
     7561 gccatgtcca tggaccatcg tgcaatttgt gatcgtgata ttttcgcaag cgatcctttc
     7621 gtacgtatct tcagtccctg ccttgattgc aatacagtca tctcccacgt caatatggca
     7681 attactaata cgcacatttt tgcatgattc tggatcaatt ccgtctgtat ttggtgaatc
     7741 cgctgggttc aagatcgtca agttatcaaa cgttgcatta ctgcaaagaa tcgggttgat
     7801 cgtccaactt ggtgactgga tcaatttaat atctttcaca gtaattcgat gacagttatg
     7861 gaaactcatc aatttaggac gaggataagc gagattatct ggttcatttc taaaagtatg
     7921 ccaccatttt tttccatttc catctaatgt accgaaacca gtgacagaga tgttctctac
     7981 attttgagca tagatacagg aagcataaac ttttcgatgg actccttccc aacgtgaatg
     8041 aacaacagga taatcttttg gatcgtcaga gaatttcaga accgctcctg cgcttaaatg
     8101 aagttcgaca ttgcttttta aaaataaagc tcctgttaga aattcacctg ctggaacaac
     8161 tacggtcccg cctccgtcac ttgctgcagc atcaatggct tgttgtattg cttcagtatt
     8221 caattcatca attgatgcgc caaatgtcaa aatatcatac atatttataa tgcctccact
     8281 tcaatcaatg cttgcaagaa tgcaccaacg cctttttgat cattacaaat aattggttca
     8341 ctgatgtagt aagcatatga accatctcgc tgatctgctc cgcctaaccc tgctacttga
     8401 cagtttttat tcaagttcag ccagccttct tttgtttcca gaacaaattc atcaagtaat
     8461 ccttgatgtg atttcttcac ttgtggaagc cattcttctt tgttcagcag tcccaaacgt
     8521 attcctttag ccattgcgta aacaaacata ctactgccgg aagcttccag ataatttcct
     8581 ttccgttttg tttctgttgt tacttgatac catgtcccgc tgttttcttc ttgatatgga
     8641 agtaatgcag ccagtgtctt ttctagaatt tctttcagca aagaacaatc tgtttcttca
     8701 tgaagtaatt cataggtatc tgctgcagcc atcaaatacc agccaatcga tcggctccaa
     8761 aaatgatggg atagacctgt ttttggatca gcccatggtt ggaccttctt ttcatcccat
     8821 gcatgaatca gcaaatttgt ttttggatcg aatagatgtt tataactgat ttcaaactgt
     8881 ctcaaaacat cttggtaatc tttttcttca ctaaaattct ggataaattc agcataaaaa
     8941 ggagaaccca tatataagcc atccaaccaa atttgataag gataaatttc tttatgccaa
     9001 aaagctcctt cggatgtgcg tggatggttt gccaactgct gggaaaggag ttctgctgct
     9061 tttttatatt tttcttcgcc tgtttctttg tacaataaaa agaaaagctt tcctgtattt
     9121 acatggtcga tattgtattc ttcaacgctg tagccacgga tcgttccatc ttcttgcacg
     9181 aaatagtcga tattgtcttt tatgaaatca aaataaattt tttcttgggt tcgttcccaa
     9241 agtaattgga accctttaag tacgacgcca tagtcataag accattttcc tttataccac
     9301 ttttcttcat ataagcgagg tgttctttcc atgatacttt ttgctaattt ctttgaccag
     9361 ttttccatta tttgctctcc tttaaaaatt aaaataggat ttgggacaaa taccaagaag
     9421 tatttgtccc aatcgtctat attactgtgc cgctgctttg tatgcttcct cgtactcttg
     9481 tgtgattcga tcgcctcctt gtgctttcca gtcttctaca gcttttttga atccatcttc
     9541 gtcaagctgt cccatgatgt attgcaccgt agcatcaatg acgatttttt caatttctga
     9601 tcctacttca ttgttcgtcg gtgaatccaa tggcacagaa ggatccatta cagcaaattc
     9661 ttcattttct ttgatcaatt gattagagaa ttctttttca gggtctgtat ctttgaaaga
     9721 gaacgtcact tcactaggac gagagcttga taacggttgc acctcttgtt gccaaagatc
     9781 catatcgata aattcgatag aaccatcatc attcaattca taatgcgttc cttcgatacc
     9841 gccagtcatc aatttataca catcttcttc taaaagatca tcaacaaatt gaagtaattt
     9901 cttcaattgt gcttcgtctt ttacttgaga tttgggaaat gctagcaagc cgccaatacc
     9961 atttccttct gaccaaacat gataaccgcc gccttcacca tctgagatct tgtttacagg
    10021 cactaattcc atatcatctt gaataccttg acccatcgtc ttcagattct tgatatccac
    10081 cattccagtg tagattccag ttcttccttg tgcaaattgt tcttgctgat cagtcttttg
    10141 ggtaactgca aagtcttgtg ccaaatagcc attctcaaat agatctcttg aaaaattcaa
    10201 agctttcata tactcttctg tatcaaattc tggagtgaat ttgccattat cgtctacagc
    10261 ccagccattt ggtgctccaa aataagaagt gaaaagttta aagctggtat aacgaatatc
    10321 actaggcgca cgatcgccaa aaccaactgt gtcgtccaca ccatttccat caggatcgtt
    10381 ttctgtaaat tgtttagcta cttcataaag ctcatccatg gtagttggaa catctagtcc
    10441 tagattatcc aaccagtctt ttcgaatgac taagccagca cgagcgtagt ctttttgtat
    10501 cggtacgccg tacaaggcac cgtcgatact cgcagcttcg attctatctt cagaaatttg
    10561 acttaaattt ttatagtctt ttaaatattc tgatacatcc cagaatacgc ctgattttaa
    10621 cgcattgcgg acagaagagt ttttcaacat cgcaatttga agtgtaacga tatctcctag
    10681 ttcatcagaa gccaatgcag ttgttaatct ttcttctttt gaagcatcag gaatccagtt
    10741 gaatgtcagt tccgtatcgg ttttttcttc gatcaagttc acaatcgtgt ctgtaggcgg
    10801 tgaagcatga tgcaaaatat ttaaccaagt gattttagct tttccatctt ctgtctctga
    10861 agaactgtta cttgaactgc tgccgcatgc ggcaagtgct agaattcctg caaaactaag
    10921 acctaatttt acgagcgttg cttttttcat aaattttctc cttcactgtt ttaataatat
    10981 ttttgttttc ttctgttttt tctgtatatg agttcttcca ttccaaatgg caaaatatag
    11041 aatttgctgt ccacgtgact gcggaaaaga agagactgcc accgataaag gttaaaacac
    11101 ctggcattgt ttggatgatc atcagataaa tccctaccat acttaatatc aacactaatg
    11161 agtaatgaag atgtgagaat ccgaataaaa atgccatttt cattttgaaa aaatatcctt
    11221 tccaatcata atgagccatg attgggaaaa tatagagtgc tgagagcaca tatatgaacg
    11281 cagcaatata caaagcgatc ctaagatacc aattgtgtat gaaagaaaga tccacaagta
    11341 aaacaatccc gatggcgcca tatatccagc tcatcagcaa ggtttcacga tagttttctt
    11401 taaaatatgt gaagtacgtt ttcgtcaaag gaaacgtttc ttttgagcgc agccattttc
    11461 taatcactgc aaccatcgca tacgatgcag gaccgaaagt aaaaactccc aaacctgcga
    11521 tgactaaacc gccccacaga aaattcaaat aaaccaactg taaaatacga tttagccttc
    11581 cgtttatttt atctaatgac tgcagcatat ctttccctct ctttctatct tagtaaacgc
    11641 cgtcttctcc tagctttttg gcaatcttat tagctaaaat taccataaac aatcctacga
    11701 cccctttaaa caatcccatt gctgtactga aacttaactg tccattcttc aatccagctg
    11761 tataaatata ggtgtcgaaa atttctgcaa cgcttcgatt caatgaattc aataacaagt
    11821 acatatgctc gaaccctaag tctaatgtct gaccgatttt tagaatcagc aaggtaatga
    11881 ttactggacg aattgccggc aatgtaacat gccatgtttt gcgtaagcgt cctgctccat
    11941 ccatttctgc agcttcatac aactgtgtat cgactgcagt tatcgctgaa aggtagatga
    12001 tcgtagacca gcccaactct ttccagatca cttgtccgat atatactgtg cgtgtccatt
    12061 caggggatgt tagaaaactg attttttcaa atcccattgt tgcaaggaat tcattcaata
    12121 cccctccgtc aacattcaaa aatacataag taatcgaaac aatgattacc caagacatga
    12181 agtgagggat gtaaatgatc gtttgaatcc cgtttttcaa tcgtttgttc gttacttcat
    12241 ttaatagtaa agacaaaatg attggcatcg gaaaaaacac gaagatattt aatccgaaca
    12301 agatcaacgt atttcttaat aatgtaaaga atgtcggttc tgtaaacaaa cgaatgaaat
    12361 gtttgaaacc gacccaagga cttcccatta ttcctaaaaa tggttgataa tcttgaaaag
    12421 caataacgag tccccccata ggaagatacc taaaaatcaa gaaataaagg actcccggca
    12481 gaatcatcac atataaaaat ttattcgttt tgattcctgc aattattttt tttcgtcttc
    12541 tgagcttttc ttcttttttc gatagcgtca gttgaaatgg ttcttgtttc tttacacttt
    12601 ccataagccc ctccttagtt ttgtgaatgt ttgctgctta tgacttcatg atagataact
    12661 atctgaatta cgtatataat catttttatc gtaagtaaaa acgcttacat agcaatgatt
    12721 tttgtgctat acaaaacgat aaagtgtatt ttttcacaaa taaactacgc atagcaaacc
    12781 ttctattttt ttctatctga cacttagcat aggaaatgat tatatacgta atctttcacc
    12841 gatgataaat tgaacatata gaaacagaaa catttaattt attttgagga ggagcctatc
    12901 tatatgaaaa agaaagtctc tataggagaa agaagtttta cacttttcaa caatacgttt
    12961 ctaattttgc tagctttgat ctgtatcgtt ccttttttaa atatcatcgc tacatctttt
    13021 gcttctacac aagaagtcgt cgcgaaaaag tttatccttt ttcctactac cttttcttta
    13081 gacgcgtatc gctacattct ttctacgccg accattttta gagcacttgc tgtttcgatt
    13141 ggtgttacag gtgtcggaac gatcgtcagt atgtgtgcaa cttcactgat ggcctacggt
    13201 ctttccagaa agtatttgtt tggtcgaggt ttcgtcaact ttcttgttgt attttctatg
    13261 ttgttcagcg gggggatgat tccaacgttc ttagttgttc gttctctagg gctggtcaat
    13321 tcttactggg ccatgatcct gcctgtagct gttaatgcaa tgaatatgat cattatgaga
    13381 aactttttcc aagccttgcc ggatagtttg gaagaatcag caaaaatgga tggttgcaca
    13441 gattttggtg tatttttcaa aattatgctg ccattagcgt taccgtctat tgctactatc
    13501 tcgctttttt atgctgttac ttactggaac acttatatga ctgctatttt gtatatcaac
    13561 gattcatcta aatggccgat acagattctt ttacgccaaa tcgtcattgt atcaagtggg
    13621 atgcaagcag aaagtagtgc cgttgatgtg attccaccag cacaaacagt taaaatggct
    13681 gttatcgtta ttgcaacagt gcctatgctg attgtttatc cttttgttca gaaatatttt
    13741 gtcaaaggag cactcgtagg ttctgtcaaa gggtgattat gtactgaacg caaaatggta
    13801 gttgtgtcag aagtggtcag cttcaagaaa taagaaggca tttacgaaaa ttgcttctta
    13861 aatttttgtg aaatttcggc ttatttttcg aagaatctac tcctggaaca ccgtgtatca
    13921 gaggttgtga aagagacgtt cagccttgag cgatgataaa aactctcaca aacattgcga
    13981 cgagtaaccc acaggagcaa taagaagcga ttttgaaaaa tagcttccca tatttcacaa
    14041 aattatgcct tattgtcgat agcctgtctc ttgaacgcca tttattcgta aaaaagaact
    14101 gtgacaagac ttttgtcaca gttctttttg cgtgcttagc cttgaaattt aactatccat
    14161 aaatacaaat actagggtta ttctaacttc ttttattgct tgaatcagtc cacaagaaaa
    14221 acagcctctt gattaaacgg cgtttatctt gttgattctg cggcaataaa atcagccagc
    14281 agcaaaacat gaagtgctgt tttttgctgt cctcttttat tgcttgaatc agatcacaag
    14341 aaaaacagcc tcttgattca caaatatttt tttcgatatt ctcccggcgt aatcgattcc
    14401 ttctttttaa agaaacgaat aaaattttgc ggatttcgat attgcaatct ttctgcaatc
    14461 tcttttacgg agaggttagt ctctttcaac catttttttg ctacctctaa acgatgattt
    14521 tgaacaaaat caccaaattt ttctcctgtt tcctttttaa atacattact taaatagtta
    14581 gggttataat gcaacctatc agcgatcaca tctaaagaca gatcacgatc atattctgtg
    14641 tagacgatat gcataatatt ctccgacaaa tttttaaatt catgatcagt gattgcttga
    14701 gagcattctg tgattggcag aactaattgt tctaaaacaa gtttttctag ttctttggga
    14761 tgataattgt tcagtgcttt tacataaatt tgtttcatgt tatcaaagtt ttttgaatct
    14821 actcccaata actgtcctaa ttgaacgagt tcattgatca agcggaccga aactacttcc
    14881 cgactcaaag gatttttatt ttgtgcaaac aatgcatcaa tcaattcatg tactaaattc
    14941 ttcacttcct gatttccaga acgaatggct tcaaacaatc gattttgttc ttctatcgga
    15001 tatctaataa gtgttttttc atgagcagca ggaacgattt cctgataaaa aataattgaa
    15061 cttggaccag tatttacacg ataatacagg gcttcttttg cccgatcaac cgattgcttg
    15121 ctttcattca gcgtttcgaa ccggttactg atgcctatac tgatagttaa attcaagtat
    15181 tcttttacac gtttttgaat gagtcggcaa tactccatga cttttttgct tgcttctgca
    15241 tcatctttat ccattcgata aatagtggct tgcatttctt cattcaaaac gatcggcagc
    15301 attcgatttt cctttggcac aatttccgtg atcatgttgt tgatcgctaa aagtagcaaa
    15361 tcacgctccc caccgtgact atcttctaac agatcgattt gaaccaaagc tgtataatag
    15421 cagtcatttt gagaactata accaaattgc tgcaaccgct gatctagttc tcgcctttct
    15481 actcgatttc taaataaact aagtacaaat agcgtttcca gctgtggctt ttgggtaact
    15541 aagtgtgcac ttaacgcttc tttttctcct atgatccgac tgactgattg agcgaccaaa
    15601 tctagttctt tcccactgaa tccttttgat ttaagattca gacgttcctg tatttgagaa
    15661 atcggacggg caaatctgtc cgaaaataag taggaaagaa gaccaatgag tcctaccagt
    15721 gttaaagaca ctgcaactag cccgattctc agattgcgga tcattgcgcc aattgcacta
    15781 gagtcaactt ctaatctgta aatccaatta ttataatctg atttcagtac tatatacgtt
    15841 ttatcttttt ctcttatcac tttcagctga ttgtaatcta gatccacgtc cgttaataca
    15901 gttggttgct ctttattttt tactgtctga gtagtaaaaa ggttgccaac ttcgttttca
    15961 atagaaagta tgtcttctcc actttcacca acaacttgtt ctattgtatg tttctctatc
    16021 gtagcaattc ccaatgcata tttttctttt tcaaacattg gcaaagaaat caccatttcg
    16081 attcctttgt ttttcttttg ccaaaataaa ttatttttgt tatttatgta cttctgttga
    16141 tacttttcaa cttcctcttc ggtcagttga ctcaacgatc cattgattac tccccattta
    16201 ccagccaaac tgactaaatc ataattatta tcatccataa caatcgtttc tataaaattt
    16261 agttctttcc tgatttcaga ataagtggag taatctgtat atgtcagcgg atgcttgaat
    16321 atgtccgaga aatttttggt cgaaccatac gtagaaaacg aatattcaat cgttctaatt
    16381 ttccattcaa cgttagtttt aacttgcctg agcaaattct ttttgtctgt taaataactc
    16441 gattcgatcg attcataggt attctggtaa atgaataaac taaatcctat gacaagtacg
    16501 gctcctaata aaaacatcgg taaaaatatt ttataaaata ctgtactttt cttcattttc
    16561 ttcctctcct ccttttaaaa taaaaggctt tcatttttct gtaaaattga tactcatcta
    16621 attaaatgag cattccccgc tttcaagaat agcataatta aaaataaaaa tccaagtaat
    16681 ttttaacgtg tgcaatcttt tcatatcaaa gatctattga cttatcgtag ttatcgtaat
    16741 atgatgaatg cgttaacaaa aagtgaaaaa gtaaggaaaa tgatggaatg gtaacgatca
    16801 aagatatcgc taaagcagct ggcgtttctc atacgacagt ttctcgtgct ttgaataaca
    16861 gcagtttaat aaaaaatgaa acaaaacaaa aaatacgaca actagctaag gaaatgaatt
    16921 attcgccaaa ctatagtgca aaaggtttag tgaatcaaaa aaaatatcta atcggactat
    16981 ttttctcaag tttgcataaa ggaacttcat caaatttcct agcagattcc attgcaggca
    17041 tccattcagt attagacaca aattacagtt tatctgttga aagtatcgat gttgttgatt
    17101 taacagaaat caacctgcaa cgctacgatg gactgatcgt tatgagtcaa agtgatgatg
    17161 atcagccttt catcgactat ctcaaagaaa aagaatttcc tttcgttgtt gtcaatcgtc
    17221 acatcaatga tccagcggtt atcaacgtca ctgccgatga tgcggccggt gttatgcagg
    17281 cagtagatta cggtattgga tgcggacata cgaagatcgc ttatattggc ggaaagaaaa
    17341 attttcgttc gacaaaagaa cgggaaaaag gggtattgaa aagtctaaaa aaagcgagca
    17401 tccctgtcaa tccagcctat tttttaacag gagattacag cttagaaagc ggcctccaaa
    17461 acatggaata cctattatca ctttctgacc tgcctactct ggttttttgc ggcaacgacg
    17521 acatagcgat tggtgcattg agagctgtac atttagctgg cctccgtgtt ccccagaaca
    17581 tttctctgat cgggttcgat gattctccag tcgtctccta tctcaatccg ccgcttacca
    17641 ccgtacgtaa gcctttgaaa gaaatgtgtc aagaaggaac aaagctttta ctagatttga
    17701 tcgaaggcag gacgatcgaa caatctaaaa ttgagctctc caccttgttg atccttcgtg
    17761 agtcgatcaa ttacttgtaa actacaagta attttatata aaaatgttaa cgtgtgcata
    17821 acacagaaag gaagtttata tgaaaaaact gacaaaagaa ttagtgaaaa aaaacgaagc
    17881 acctgtaaaa gttcttcagt ttggtgaagg caattttatg cgtggattta ttgattggca
    17941 gattcagcag ctgaataacc aacaattgtt taaaggtaat gttgcaatca ttcaaccttt
    18001 agaacaaggt cttggaaata tgatgaacca gcaagataat ttatatacgg tcattttaca
    18061 aggactcagc aatggcgaaa tcgttgatac ttccgagatt atcaccgtag tagaacaaat
    18121 gatcaatcct tatgatgaat gggatgctta tctatctcta gcagaaaatg acgacttggc
    18181 ctatatcgtc tccaatacaa cagaggcagg aatccaattc gtggagactg ataatttaac
    18241 agatactccc ccacagagct tcccgggcaa actgacagcc tttttatacc gacgtttcaa
    18301 attaaacaaa gctggcttta ccatcattcc ttgcgaactg attgacagaa acggcgaacg
    18361 tctaaaagaa atcattttac gctacgcaga aaaatgggat ttagaacctg cttttgttga
    18421 gtggttagaa aaagaaaatg ttttctgttg tagtttagtt gatcgcatcg tcccaggtta
    18481 tcctcgcgaa gatgcaggtg ttttcaatca acggcataac tatgaagatc aattgatggt
    18541 caaagcagaa ccattcatgc tttgggtgat cgaagggcct aaagaattgg agaatcaact
    18601 accattcaaa caggctggct tgaatgtcat catcacagat gatatgactc cttatcgtga
    18661 acgtaaggtg catttgctta atggaccgca tacagcgatg gtccctcttg ctttgttggc
    18721 ggaattggaa actgtagaag aagtaatgaa agatccttta ttctccgcat atgttgatca
    18781 gttattcaat ctagaattga ttcctatgct ttctttacct aaagatgaat tagccattta
    18841 tgctgaccaa atcaaagaac gtttcttgaa tccttttgcc catcacaaat tagaagcgat
    18901 ttcattaaat agtgtttcaa agttcagcac ccgtctgctt ccagtgttca agaagtatat
    18961 cgaagaacaa aatcaggtac caccgttaat cactgtttca ctagctgcgc tacttcttat
    19021 gtatcgaggc gatcaagtaa agccacatga tgatgaaaag acgataagcg aatttactga
    19081 tgcttggtct gataatggaa cagctattcc tcgattattg caaaacgctg cgctttgggg
    19141 agaagatttg tctcaaatac cgaatgtgac agatacagtt caagaaatag ctgcaaagat
    19201 cgatcaaaaa ggtgtccggt cagtattaca agaaatgaaa ggaacgatgg tccatgcttg
    19261 aaaccctgca accaacaatg aaattaaatc gacgagacag tgtggtcgtc gcattaaccc
    19321 ctattccaaa acaaacacaa ctgacgattg atcagcaaac gatcaccact cttgaagata
    19381 tcccgcaagg tcataagatt gcattgggtg atttgaaagc tggagacaac gtgatcaaat
    19441 atggctatcc aatcggtcat gtgacgacag acgtaactgc cggtcaatgg ctgcacactc
    19501 ataatgtaaa aaccaatctt tctggtgaat tggattatcg atatgaaaaa gatgtccatc
    19561 caagtcatta cctttttgag aaccgaacat ttcaaggtta cttgcgaaaa aatggaaaag
    19621 tagggattcg taatgatttg tttttagtac ctaccgttgg gtgtgtgaat ggcattgctg
    19681 aactgatcgt caaacagttc aaggaaaaac atccagatct gggacagttt gaccatatta
    19741 cgattttaaa gcatccttat ggctgttcgc agcttggaaa agatcatcaa aatactcgag
    19801 aaattttagc ggacgcagta aatcatccca atgccggagg agttttagta tttggattag
    19861 gttgtgagaa caatacagtt cctgaattca aaaaaatttt aggtgaatat gatgaagaac
    19921 gagtgaaatt tctagtggct caagatgttt acgatgagat cgaacaaggt gtggctctat
    19981 tagaagagct tttaacagcg gcggaaaatg accagcgcat atcagtcccg ctctctaagt
    20041 tgaatgtcgg tttgaaatgc ggcggttctg atggtctatc gggaataact gctaatcctt
    20101 tacttggtgc attttctgac tacttgattg ctcaaggagg cagcacgatc ttaacagaag
    20161 tgccagaaat gtttggcgca gaacaagtat tgatggcacg agcggaaaat gaagaagttt
    20221 ttgactcaat cgttgacttg atcaatgact tcaaacagta tttcttgtct tacggggaac
    20281 cagtttacga aaacccatct cctggtaata aagcaggtgg gatcactaca ttagaagata
    20341 agtctttagg ctgcacgcaa aaatcaggaa gctctcctgt cgttgatgtg ctacaatatg
    20401 gcgaaaaaat cagaaaacca gggcttagtt tattgcaagc tcccgggaat gatcttgtag
    20461 ctgcctctgc tcttgcttca tccgattgcc agttggtctt gtttaccaca ggaagaggga
    20521 ctccgtttgg ctcatatgtc ccaacggtca aggtatctac gaatacaact ctttttgaac
    20581 gcaaaggtca ttggatggat tttaatgcag gcgtcttatt agaacaacca atggaagtaa
    20641 tcttagaatc gtttgttcaa aaaatcatcg ctgtagctag tggagaagaa acgaaaaatg
    20701 aacaaaatga cgttcgagaa attgccattt ttaaaaacgg agtaacactt tgattttcat
    20761 aaaacagtat aaaaagaaag aaggaagatt tatgttttta tctgatgatt ttttattaaa
    20821 agacgattgg gcgaaaaagc tttaccattc ctacgcaaaa aacatgccca ttattgatta
    20881 tcactgtcac ttagatccaa aagaaattta cgaaaacaac aatttcagca atctgacaga
    20941 agcttggtta ggaggcgatc attacaaatg gcgcttgatg cgagcttgcg gcgtgcctga
    21001 agaaaaaatc acaggaaatg cttctgattt tgaaaaattt ttagcttggt gtcaaaccgt
    21061 accaaaaatt atcggaaatc cgctttacag ttggtcacat cttgaattga agcgtttctt
    21121 cggtattgac ttgttgataa atgaagaaaa tgcagagaaa atttggacac aagcaaatga
    21181 aattttggca gctcctgatt ttcgccgtcg ggaaatcgca aaaaaatcga atgtagaagt
    21241 gatttgtaca acagatgatc ccgcagacga cttgcactat catcagttgc ttgctcatga
    21301 agaaccagat ttgaaggttc taccttcatt ccgtccagat aaagcactca atattgaaaa
    21361 agaaggattt aatgcatggg tcacactact ggaagaagca gctgaccaaa cgatcaccac
    21421 ctatcaagaa ctgatagaag tcttagggca gcggatagaa tacttccatc aacatggatg
    21481 tcgtgtttcc gaccacgctt tagacatctt acgctataaa gaagcggatg aaacagtatt
    21541 agaagagatt tttcaaaaag cacgagctaa caaactatta tcttcagatg aaatcgatgc
    21601 ttatcgtaca gaaacactga tacatttgac ccacttctat cattctcata attggacgat
    21661 gcagctgcac atccatgctt atcgtaactg taatacacaa atgttggaaa aattagggcc
    21721 cgataccggc tatgatggaa tgaatgatct ttctttgact attcctctgc aaaaattatt
    21781 gaaccgtgca gaagaaacgg atcagttgcc aaagacgatc ctttattcat tgaatccgaa
    21841 tgactatcct gcgattttag ctttgatggg ctgtttccaa aaagaacaga atggaaaact
    21901 gcagttaggt tctggatggt ggtacaacga tactcgagct ggtatgcgcg atcaattgac
    21961 acaatttgct gatggtagtg ctttggggaa ttttgtcggc atgctgacag attcaagaag
    22021 tttcctgtcc tacactagac atgaatattt ccgtcgtgtt ctttgtgaat ttttaggcga
    22081 aatggtcatg cgaggagaag cacctgaaga tgaacaactt ttaggaagtc tagttcaagc
    22141 gattagttat acaaatgcta aaaattactt tggctttttt gcctaattga ttaatagtaa
    22201 cagtaacgaa tcaaaaacag gatagtgaaa taacggaatc cgtttatcca cgttttagag
    22261 aagaagacgg accaaatttg ctccgtcttc ttctcttgct gttctgcttc attgcctata
    22321 aacctttatg aaagaagaga taacatgcct actatccata ttgccggtga ttctactgcg
    22381 gcagaaaaag atgaaaacaa gcgtcccgag acaggttggg gagaaaaaat ctctgcttat
    22441 ttttcacccg agatccagat caataaccaa gcaaagaatg gacgcagcac caaatcattt
    22501 atccaggaag gaaggttagc ccgtctagct tcacagtttc agccgaatga tttcttattt
    22561 gtacaatttg gacataacga ccagaaaatc caagaagaaa gaggtacgct tcccttcggt
    22621 agctatttaa aaaatctgca gatatttttt gaatgcgcaa aaaaagcgaa cgtccaaatg
    22681 gtcttactga catctgtgac gcgacgagat tacttagaaa acggaacatt gaatccagat
    22741 atacttggag actatccaaa agcgatgcgt gcatttgctg agaaacacca tattcctctt
    22801 ttagatgtgt tctcaagatc acaagaattg tcccagacct tctcaaaaga agagacaaaa
    22861 aaattctacc tgcatcttat gcctgatact tgtaaaaatt acccagaagg actaaaagac
    22921 aatacccact ttagtccaga aggcgctgat aaagttgccc gaataattgt tgaattgata
    22981 aaagaatccc gtctgcctct tgctaattat ttacaaaaag gagtttgaga tgtttccatt
    23041 aaatttaggc atccgtgccc acgatttaga tgttcgaaat cgtgaagaaa tcgttcaaaa
    23101 agtatcacag cttcacttgt cccatatcca atttgcacca caaaaagcat ttcctgaaca
    23161 acttaaatta actgacatga cacttgggag tgctgcctat tttggtgaat acttccaaaa
    23221 aaacaatatc gaactttcca ttttaggatg ctatatcaac ctatccagca aaaatcaaga
    23281 agttcgtgca caagcattgg caactttcaa acagcaaatt gctctgtgct ctgcctatca
    23341 agccaagatg attgctacgg aaaccggtag tgtctctgtc ggttacacaa aagaaaattt
    23401 tactgaagaa gcttatcaga tcgccagaaa ttctatcatt gaattagtcg ctcatgcaga
    23461 aaattttggc gtaactgttg ctgttgaagc agggatcaat catccaatct ataactatca
    23521 gttagctaaa cgtttaatcg atgaagtagc ttcaccaaat ttaaaaatca ttttagattg
    23581 tgcgaatttg atgcataaag aaaatcatgc tgatcaggaa aaagtgatcc gaggtgcctt
    23641 ggacaattta catggttata ttacagcgct tcatctcaaa gactatatca tggaaaatgg
    23701 aaagatccgc atggtacctg ttggcaaggg ctgtttagat ttccgcccgg tactgcatta
    23761 tatcaaatat gagcgtcccc taatgtacgc cactcttgaa gctactcctg agatttatgt
    23821 tcctgaagca atagaacact tgcagtttat ttaccaagat tgttaaggag aagattatgg
    23881 aggaacgaat acagaaaagt tatcaaaaat atcatgcaaa tgcttttcag acattgctgc
    23941 atctttatca gggaaattat tggcgttttg ccatgtcagg actctttttt attatcaaac
    24001 atcttccatc ttggttaatg ccgatcgcta ttgccaatgt aatcaatgca gcttcatcga
    24061 aagattcttc tcagttgcag gccatttatt tcaacgcttt tttgatggct tgtctgattg
    24121 gtcaaaatat attgacgaat tattttcatg taaaatacca tagcacttcg atccgtcaag
    24181 tagaagctgg actaagagcg acccttatca agaaaatcca agaactatct attccttatc
    24241 aaaaagaatt gcaatctgga cgaatccagt caaagatcat ccgtgatgta gaagctatcc
    24301 aaacgttgtc ctctcaagta tttgtcagcg gattaaatat cgctgtcaat ttattcgtag
    24361 ctttaggtat cacgctttat aaaagtcctg ttgttttcat gtttttctta ttgactgttc
    24421 ctctcgccgc attcgttact ctctttttcc gtaaaaggat cagacagtcc aactcagact
    24481 tcaggcaaga aatggaagag acttctgcaa aagtgatcga agtgatcgaa ttagcaccga
    24541 ttgctcgagc tcatgggtta gaaaaacacg aaacaactcg cttaaataag cattttactc
    24601 aaatctatga aaaaggattc cacttagata tcctgcaatc tgttttcgga tcagtcagct
    24661 gggctagttt tcagatattt cagctgattt gtttgatttt cactgggata ttagctttac
    24721 aagggcgcat ccaacccggc gatgtcgtga tgtatcagac gtatttcatg acgatcgtca
    24781 attccgtttc tggaatgatc acgctgattc ctacgatttc aaaaggcatg gaatctatca
    24841 cttctattgg cgaactgttg attgctggcg atgtagaaac ttatcacggt aagaaaaaaa
    24901 tccaacattt ggatggaaat tttcgttttg aggatgtttc ttttctttat ccggactcac
    24961 tcaaaccgat tatcgatcat ttttctctag aggtgaaagc tggagaaaca attgcttttg
    25021 ttgggccatc tggctctgga aaatctacac tccttaactt attgattgga tttatccagc
    25081 cgacttcagg aaaaattttt ctagatgatc agcctttgga tgaactggat atgcgaagtg
    25141 tgcgaaatta tttagccgtt gttcctcaaa ccactttgtt gttctccgct tcgatcaaag
    25201 agaacatcac ttatggcttg aaaaacgtat caaaagaacg tttagatgaa gtcatcgaag
    25261 ctgcgcaact ttcttcactg attgaccagc ttcctgatgg tctggatacc ttagtaggcg
    25321 aacatggcaa caagctgtct ggtggccaaa agcaacgtat ctccattgca cgagcgttga
    25381 tacgtcagcc aaaaatcatt ttgctagatg aagcaacctc agctttagat aaccagtcag
    25441 agaaaaaaat ccagcaagcc ctgaattacc tgacagaaac acccactact tttattgtgg
    25501 ctcatcggct ttcaacgatc aaagaggcag ataaaatcgt tgtgatcgat gaaggaaaaa
    25561 tcgttgaaat aggtacttac gaaaaactgt tagctcaaaa aggctatttc taccgcttga
    25621 aaaatgaatg acaaaaaata ggagctatga caagactttt gtcgtagctc ctatttctga
    25681 ataaacggtg ttctcctgcc aactcctcgg tcacaagtca caatagtcat caaacatgag
    25741 aagctgtttt ttgaaattgt tccttgtaac tcagagttaa acggtaggct cacgacctct
    25801 tggtaaatgg tgttcaagag acagcctatc ggcaacaaga agcaattttg tcatcgctca
    25861 aggccgaacg tctctttcac accctctgtt gtttcataaa atagttttat tcgctgtaaa
    25921 ggtcgcgaac tggtgtcatg atgatacggt tcaagtcatt gatgattgta ctgaagcctt
    25981 gctctttttg catcaagtca ttgattactt cttctgattg gattttcaca gccatttctt
    26041 gtgctttcat tgcatcttcg tcgctgaact cttgtccact catttgtttt tcttgtaatt
    26101 cgatttgcat cgcttggaag tctttgaaca gtttgtgtgc ttcttcgttt gcttgtactt
    26161 tctcgtacgc ttctttcaac gctttgaatt ctggtaattc acggatctca cgttcgattt
    26221 gattcgcgct atcgtagatg tttgacatgt tatgccctct tttcttttag tagttactct
    26281 ctattgtaac atggggttat tcgttttcaa aggggctact ctccttgata tttccgccag
    26341 aggtctttag ccgcttcacc aattccctga acgccttctt tcaccatatc gccgaagttt
    26401 ttcagccctt cttttgcttg ttcaccatat tgattcaagt tatcttgcca atttccagac
    26461 tctccattag aatttcctgt gtttccaact tgatctgcag ctaccacttg tcctcctgtg
    26521 gcataggcat ctgctacact aaatcctgtt tttgaagtat acggaaggat gccttctgcc
    26581 gctgatttga agactttccc gacaacattt ccacttgtcc cttccaaata gtgcagcttg
    26641 ctggattctt cgtaacccat ccatgtcgaa atcactacgt ctggcgtgta accgatcatc
    26701 cattggtcat ttgcttttgt ggcatcgaaa ttagtttctg tggttcctgt tttccctgct
    26761 atcgtataac ctgcaggatt cgcagcagcc gctgttccat ttgaaaatgt accaagaagc
    26821 atgctggtca tttcatcggc tgtttccttt gatatgacct gttttggttt tttgtttgtg
    26881 ttatcgacga tcaccgctcc agtcgaatca acgattttcg tgataagatg cggcgtatac
    26941 atctgaccat cattggcaaa tgcactgtaa gcacccgcca tgatcaatgg agatactcct
    27001 ttttccagtc caccaagggc taagccataa tacttatcag attttgctaa aggcaggccg
    27061 aattcttctg ctttatcata tcctttttgt aaaccgatct catgcaaaag ccatacagca
    27121 ggcaaattca aactttgtgc aacagcttga tacatcggta cttctccttg gtatgtcccg
    27181 tcaaaattat gcgcatcgta ataactttgc ggttcgtctt tcaagatact ggaaggcttg
    27241 tatccagctt ccagtgctgg tgtatatacg cttaatggtt tgatcgttga tcctggtgaa
    27301 cgacgcatct gtgtagcaaa gctgaatcct ctaaagacat gatctcctct tcgtcctact
    27361 agtgcttgta caccacctgt attcggatct aaagctactg aagcagattg gaccatggca
    27421 ccatctgaag catttgctgg gaataatgca ctgttttgat aagtagcttc taattgcttt
    27481 tgataatcct gatctaaagc tgtatagatt ttatagcctt tattcatgac atcttcttca
    27541 tcaagaccat actcgttaac tgcttcatcg atcactgcat caaaataata aggataacga
    27601 taaccagaat ctgaattatc gtatgtgtca ttaagatacg cgctgatatc tgtctggctt
    27661 tctgcttgtt cttgttcttt tgtgattttt ccgttttctt ccattacact tagtactgtg
    27721 tttttccgat cattcgcatt ttttgggtga tcgatcggat tataaatacc aggacctttc
    27781 agcattcctg ccaaagtagc agcctcagac agcgtaacat tcgttgcatc tactccaaaa
    27841 tactttctgg aagcgtcttg gacaccccat accccgttgc caaaataggc attgttaaga
    27901 tacatggtca agatttcttc tttgctgtac ttcttttcga tctcgattgc caaaaataat
    27961 tccttcgctt ttcgatcaaa cgtttggtct aatgtcagat acgcattttt ggcaagctgc
    28021 tgagtgatcg tacttcctcc gccccctgat gttccgccag acaagaccat tcggactgct
    28081 gcacgggcaa tccctttgat atcaaacccg tgatgctcgt aaaaattcct atcttctgtc
    28141 gagattactg catcttggat atagggagaa atcgcgttta attctacata tgttcctttt
    28201 tgggcgtaca gtgtgccagc ttcttcgttt ttcttatcat aaatgactgt cgattggctt
    28261 aatcctgatt ttaacgtttc gacatttgct tgttttgcta aaataaagag gtagatactt
    28321 gtcactaaga cacagatcaa accaatcagc aaaatcaatt tgttcacatg atattttttc
    28381 cagatgcgct ttcgccatcg atggaattgt ccgagatatg gtctgatcca acgccaaaaa
    28441 ctgatcaaag cagcttttat cttttctaaa atgctttgaa aatccatttg cttcttctcc
    28501 tgtctatttg attcaatcgt cttattttac catagtgaaa gagtgttttc ttcctgctta
    28561 agttgtagtt caatatgttt ttttacgtta gtgcaagtag agtaacataa gaatgaacag
    28621 aaaaatgtaa gttttttctt aaatatgttt taaaaatggt acaattagtc tgcaattgca
    28681 ctgaaaggag tacacttgtg aaaatcacga tcactttacc tatgaaccat cctgaaacaa
    28741 caattcgcga cttgcttgaa aaggaatggt tagttcctag aaaggttcga cactttttgc
    28801 gtatacgtaa aaacgtttgg atcaatcaac aacctgcttt gttccatcat gaagtaaagg
    28861 gcaatgacca gatcacattg ttattcgaag aaacagatta taattatcaa gaagttcaat
    28921 taggagatgc gaagcacatc cgtgttttat atgaagatga gcatttgatt atagtggata
    28981 agcctgcagg aatgaagact catccaaatg aaccgacaga aaacagtacc ttactcaatc
    29041 atttagctgc ttatctcgac actaaacagc aacgacctta cgttgtccac cgcttggaca
    29101 aagaaacaag cggtgccgtt ttatttgcaa aaaatccatt tgtcttgccg atacttggaa
    29161 gaatgttgga acaaaaaatg atctatcgga gatatcaagc catcgtatgg ggagaaattg
    29221 ccaaagatat gaccatcacc aataaaattg gacgagatcg ccatgatcgg agaaaaaggg
    29281 tcgtagatga taaaaatggt cagagcgcct tgacacatgt cactgtcaac aaagtacttt
    29341 ctgaacaaac acaagtctat tgtgttttgg aaaccggacg tacacaccag atcagagttc
    29401 atttagctca taagggacat ccgatcgttg gagaccctct ctaccaaaat agaacagctg
    29461 aacgactgat gctccatgca ttagaactgc acatgatcca tccatttact caagaaaaaa
    29521 tagtcggtaa agctttacct ggattatggg aatagaaata aaaaagaaca gagtcttatc
    29581 agcagataat gataagactc tgttcttttt gtgtaatttg tctgcttact tttgatgttc
    29641 gtgttctgct aacagcaaac taccgataat cccactttca ttcggcagtc cccaacgaac
    29701 gatatattca cttacttgag gtgtttccat ataaccaccc atcaattcaa caaattgctg
    29761 acggattttt tgaaggagat gatcctgatt cattacccca ccgcctaaaa taatcttttc
    29821 aggtgctaac gtcaacgtat agttgatcag tgcttgagca atataataag cctgaatagc
    29881 ccaaacagga tgatcttgcg gcagatcttg ccctttgatc cctgtgcgtg cctcaataga
    29941 cggtcctgct gctaatcctt ctaaacaatc tttatgataa ggacaagtac cttcataatg
    30001 gtcatctgga tggcgtttca cccaaatatg tcccatttca ggatgtgcga tccctgaaaa
    30061 aatttcttca ttgatcacga cacctgcacc gattcctgtt cccacggtaa ggtaaataca
    30121 actatttttt ccttgtgctg ctccttgctt caattcccca tatgcagcag cattgacatc
    30181 cgttgtccaa gcagcaggaa tattgtagcg ttccttgatt gtgccaagaa aatcgaattg
    30241 tgcccaccct tttttgggag ttgccaaaac gtatccgtaa ttatcttttg ttttgtcgat
    30301 accaatcggg ccgaatgagc caatcccgat tcccttcaat tcataacgat caaaaaattc
    30361 aaatacctga tccaatgttt cttctggtgt tgtggtaggg atacttaatt tttctaaaat
    30421 ttctccacca tctgaaaccg cacacacaaa ttttgttccg cctgcttcta ttccgccata
    30481 cattcgtttt cctcctcgaa tccgattgtc cgaatctcat aaggttggat tattgggaca
    30541 accgcttgct tcgttggttc ttcaagcaga ttcaatatga cagtttttcc attgtcttta
    30601 gttatttcca atttttctaa atgactagac atattgaaac ctcttactac tactttatca
    30661 ctaaacttgc tgcgtttcaa agctgtaatt gcaaacgttt cactttttat cgttaaatat
    30721 tgttgttttg aaatcaatgt tccttcatga tgtttgattt gttgagtgga aaaaggaatc
    30781 tgtgctgcgt atgcatgcaa ataagtagag aatttttctt ctggtccatg tagttcaatg
    30841 ctgtaattga accgatgctc acctagacac tgtgcttctg gtgttggaaa atatccccaa
    30901 tcgcctagtt ctcccacact gcgaagtagc gtcactgcga tttgtccgtc ttctgttact
    30961 tcatattcat tcaaaccaaa gtttccgact gttacaccgt actcttcatc atgaatattg
    31021 acaaatgctt gctgatgttg cggattcgtg gggttttccc aacttttaga cacatggttt
    31081 gggcgcttca ccacttcaaa aatactatct gcttcgtgat gttccacatg taactttgta
    31141 ggaaacaaga cacgtaagcg atgatctttc atctgattgt cgagagtcgt ttcaaagtcg
    31201 atttttttac tatcttttct gattgtcatg attgttttta tttgaaggat tcgtttttct
    31261 ttggatcgtt ctgcttttcg ataacgaaat tccacaacca tctgctgttc tttttctaaa
    31321 cgctcgtctg cagaaacagg gatttccatt tcctgtagaa tacttatttt tgctatttcc
    31381 ggtgtatcta ctaatacttt tacttcagag ttttctttgt tactggatag gattggctga
    31441 tcacagaaag gttgtttaaa gatatactca tttcctatat cgccgatatc ttcaaaaata
    31501 tgcagattat tcaactttcg tttgtttttg cgatcttcca ttgtaatggt accatttttt
    31561 tcaatcgtca aatgtagagg gccgttttcg atgattcgtc cactctgatg aatcattgtt
    31621 tccttttctt ctgctttcgc ttccccttct acaagcgcga atgtttccca agaaaatgct
    31681 ggcatgtttt ctaatggtaa agtcactttg atcattcttg ccatatatgg cacacggaaa
    31741 cggtctttcg gcaaatcata accaaattgg acagtttctt cagataaaat agctggtata
    31801 gtggccccac tttttgtttc tacatgatac ttacgtttag gcaaattttc taactcttga
    31861 tatagttgtt caggtattcc ttcagcgaat ctttttcttt ctaattcgat ggttatttct
    31921 gcttcaccag ttttatccat tcctgcagta tttacaatga caaatggaaa gctgtctttt
    31981 gggaatccgg tcgtatcgat tgctgcggtc agctgttcta aggaatcttg tgcaagatac
    32041 tttccaactt catctgcttt ttcaaaacga ggtatcattt cccgatggac agaatcgact
    32101 gaacaaccgc aaatactgtc gtgaggatga ttttgcatta atgtcttcca agcataatct
    32161 aattgatcat ggggatagtt tccactaact tcataagcca tcgtcgcaag tggttctgta
    32221 atattttcta gctgtcgctg gaccttggta ttccattgtt ttaagtaaac ccgagcagat
    32281 gctgtattgg ctaaagtata ccagccatcc gtttcttgac ttgtcaattc tccttctact
    32341 gagcctaagt cttctggcac atctttttga actgcttcca gatagtcagt aaaattagaa
    32401 tgaataaact cgtaatctgg aaacagttca tttgcgagat ggattgcttt tgatatatct
    32461 ttttgtaccg gttgatgatc aacaccattc atcatcaata agtggttcgt agaggcatat
    32521 tgttctgcat ccgctaattt ttgcttccaa aaggcaagag ctgcttcttt ttctactgga
    32581 atctcattcc cgttgctata ccaattggca aatagcagac caaagattgc tgtttgatca
    32641 ggtcctttcc accacatctc tgagtattgg gaagaatagt tttctgcttc caaaacttga
    32701 ttatcaaagc caattggttt tacaccacgg ccaaacgctg ctgctgaaat accagcttgt
    32761 ttcattaatt gaggcgtctg tcccatattt ccaaatgtat cgggaaaata gcctaacatg
    32821 acaggggttc cccatttacg gctttcttcc atgccaatca gcatatttct cacgttcgat
    32881 tccgagctga taagaaaatc atcttgcaag atataaaatg gtccaattct caattttcct
    32941 tcattgattg cttgttggat tgcctgtctt ttttctggcc ttacttgaag atagtcatct
    33001 aaaataatcg tttgcccatc caaatgaaaa ctgttgaagg acggatcaac ttcaaatagc
    33061 tctagtagat cgtctatcaa ttcaatcagt cgcatgtgat gctgttcgta agccatgtac
    33121 cattcacgat cccagtggct atgagaaatg atatatactt tctttttcat ttacgatacc
    33181 tcctactttt ctactctaat atcaaagtaa tccatgacta attcgcaaaa catcatattt
    33241 gcccaagaaa accattctct cgtataattt tcaggattgt tcacatcgaa tccttcgtgc
    33301 ataaggtgtg ttcctgcgtc agttgctaca agtaaattca atatccgctc tttttcagat
    33361 ttgtctgacg ttgtcattcc ttccatagct aatgcaatcg gccaaacgta tttttctggc
    33421 gtatgggagg atccaattcc ttttgcgtac tttccttcat agaaatatgg attttcttta
    33481 ctcaacaatg ttcttcttgt ttgcagataa tcttcctctt gttcagaaca atatcccaag
    33541 taaggtgcgg cgatcagatt gggcacatta ctgtcatcca tgactgtggc gtttcccatt
    33601 ccatctactt catatgcata aatcgtttgc cctttttgat taaccgttcg tccgtgattc
    33661 tgaatcccct cttggatctc tttcttcaat ttctgtgttt gctgtacaat ttctttatca
    33721 tcgagtatcg tttgaaaaat ttcttccaca taacctaaca cgaccaccgc aaacatattg
    33781 gatggtacca gatatccata acggcaagca tcatcgctag gacggaaacc agaccatgtc
    33841 attcctgtaa aagctgtttt tgcacctcgc ccgtcattga tcagcgtatc ttcttttctt
    33901 gtcgtgtctc gtacaaatgt ataaggagag tgttcatgat cttgctctgt tttgaacacg
    33961 tccaagattt ttttgatacc ttcaataaaa gattgattga attgatcagt ttttcctgta
    34021 tttttgtaaa gaagataggc caactgtatt gggtagcata aagaatcaat ttcatatttt
    34081 ctttcccaga tccaatcgtt catttttgta tgatctgttt ggtggccagc accgttagct
    34141 tcttcgttga aggcattcgc atatggatcg atattgatat aaaaaaattg ctttttgact
    34201 aacccgctga tcatgtcagc taattcctca tcttcttttg caatcactaa ataaggacga
    34261 acttgtgcag tagagtctct taaccacatc gctggaatgt ctcccgtcaa taaaaaggtg
    34321 gttccgtcat tttgcttttt gactgttgtc aacagagtat tggcaaatgc tgctgtaaaa
    34381 ttctttgccc agtccgcatg gatatcccca catttttgtg tgatatcttc cataaatttc
    34441 tgcaccgatt ttggtatatc tttataaacc actaataaaa ccttctttct atttgatata
    34501 tctttaaaga ttatacttca tacagccaat tatgtctacg ctttcaaaaa atatcttttt
    34561 atttactttt tcatccatta tggtattatt tgaatatgat atatcattaa gaggtgttta
    34621 tatgaatcaa ccattgtacc agacaatatt taatgatttg caaacggcta ttttaactgg
    34681 tgaattacct gtagacagcc aactaccaac tgaaaaagaa ctttcacgta cctataaagt
    34741 aagcagaatc acttccaaac gtgcattgac tgaattagag caattaggac ttatttatcg
    34801 cgttcgcggg aaaggcagtt tcgttaaatc cgcttctccg gaacagattc ttgcttctcc
    34861 tacaaaaaca cgacggattc tgtttcttct tccatatgtc gctgatttgt ctgttggtga
    34921 ttttagcaag ggattgaacc ctgtgatgca agataaacag attgatgtca tgatgacgac
    34981 gcttgacttt ctacaaaata aaacagcaaa agagctaatc aatgaatttg acggattgat
    35041 ttattatgct cttgatacag aacaacatct tgacttactt tttgagcttt cattgaaaga
    35101 attccctgtc gtcatattag ataaaaaaat ctatgagtta ccttttccta ccgttctttc
    35161 cgataatttc caaggcggtg cgcttgctgc ctcttatttg atcgaacagg gacattcaaa
    35221 aatcgcttat ttgtttggta cgcagactca tccacaatcc gttcgacagc gttaccttgg
    35281 ttaccttgaa gcattggaca aagctggttt gactttccac acttcactgg atgacaaaag
    35341 cgcgacatta gatgaattgc tttcttatat cactaagtat gaagtaactg cttttgtttg
    35401 tgaaaacgat gttgtcgcta tccagaccat gaatctcttg agacagcatg gttatcatat
    35461 ccctgaagat ttttcaatta tcggatttga tgatatccaa gcagcagctc ttgttgaccc
    35521 gccactgaca accatcgcac aagattttga acagttaggt aagcttgcgg gagatgcttt
    35581 ggtcacttgg ttagagacaa aagatcgacc atccgatagt aaatttccag tttcattcat
    35641 caaaagacaa tcaacaaagg agaaataaaa tgaatatcgg tcaaatagat actagacatg
    35701 caacagcgaa tcagccaaat ttctctaatg ggaactgcca gccttatact ggcgttcctt
    35761 ttgggatgaa ttattttgca ccgcaaacta cggatcaaaa cggcagctgg tggtttcatc
    35821 ctgatgaccg cgtttttcaa ggctaccgtc ttacccatca accaagtcct tggatgggtg
    35881 atttcagtca tatgctgttt acgccgatca atggaaaact acaggagaac acccttttcc
    35941 atgctcaaag ttcttaccgc ccagaagaaa gtatattttg cccgactcat ctgtcgatct
    36001 gtcaattacg ttatggcatc tgttctacat tgatacctag catgtatggc ggaatcttat
    36061 ctattgatta cagcaaaaat gacagcggtt tacttttatc ctttccggga cgccatcagc
    36121 tctttgttat agatccttac acagtggaag gaaaaatcac acattttgct ggttcagaag
    36181 atcctgattt ttctttttat tttatattga gatttgaata tcctttaaca attgatgagt
    36241 tagctgtttc caacaaaaat agcgactcga tcccgttgta ttttgaacag acaaaaaaac
    36301 aaactatccg atttgggaca tcttttatca gctcggaaca agcagcttat aacctggaac
    36361 tagaacaaaa ccaaagcaaa gagacttacc ttgctcacag tcaagaacaa tggcagtcct
    36421 attttgatcg tatacagctc acacaccatg atcaacaaca attgcggacg ttttatcata
    36481 atttatatcg ggtgttttta tttccacaaa cattttatga aattgatcct agtgggcaaa
    36541 aaatccacta tgatacgact agtcgatcta taaaacctgg tgttctctat acaaataatg
    36601 ggttttggga tacgtataaa acggtttatc ctctttattc tttgattgct gtagaaaaat
    36661 acgaagaaat gctggaaggt tttttgaaca gctatagaga aagtggctat ttgccaaaat
    36721 ggctgtctcc tgatgaacgt ggacttatgc ctgggacatt gatcgatgcg gtcattgcag
    36781 atgctgctgt aaaagatatc cgacgagact tgatgcctga atttctaacg gcaatggaaa
    36841 aaggtgctac ggttcaaagc aaacatccaa attatggacg ccaaggaaca gaagattact
    36901 tgacatatgg ctatgttcct aatcactacc acgaatcagt caatcacaca ttagactatg
    36961 cttatagcga tttttgtatt agccaagttg ccaaggtact agaagaagag gaaatgacga
    37021 agaaatatca gcagcaatca ttgaactatc aaaatatctt tgactatgag tcaggattta
    37081 tgcgttcaaa agataaagat ggcaagttca gagaaccatt ttcagctaat cgttggggac
    37141 aagattatgc agaaggaagt gcttggcaaa gcagctttgc tgtttatcac gatttttcag
    37201 gactgatcgg aaaatatggt ggcagtgaga gatataaaga aaaactcatt gagctgtgca
    37261 atcagccccc aacgtttgac ccaggaggat atggttttga gatccacgaa atgagtgaga
    37321 tggccgcgat agaatttgga caattagcta tttcaaacca gccaagtttt cactatcctt
    37381 acttgttcag ttatatagga caacctgaaa tggcacagcc actgcttaaa cagttgatga
    37441 ctcagacctt cgacgattct ccaatgggtt accctggaga tgaggacaat ggaagtatgg
    37501 ccgcttggta tatcttcaat agtctgggat tttatcctgt cacgcctgga accggtgaat
    37561 atgttatcgg tatgccatta attgacaagg ctgttttgct tttgtcaaat ggaaaggaat
    37621 tgacgattga agcaacgcct aatcggccgc agcaacaatt tatccataaa atcaaacgga
    37681 tggacaaaga atatacgaaa ttatatttta cccatcaaga tttgctgaaa ggcggcacga
    37741 tctcttacca attagggatc atccctcacc ctaagaaata tcaagcaaaa gatttgcctt
    37801 tttccttatc aaactataat taacaagagg ttgtgaaaaa gctgtcctgc atcaagtaat
    37861 aagaacagcc aagcaaaaat agatcctcat atttttcgtt tggttggtct tattaccgca
    37921 gatgcaagct tttgaacacc gtttattgag aggttgtgaa atca
//
LOCUS       DACGMI010000026        37665 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.027, whole genome shotgun sequence.
ACCESSION   DACGMI010000026 DACGMI010000000
VERSION     DACGMI010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.027"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..394)
                     /locus_tag="IXT46_001435"
     CDS             complement(<1..394)
                     /locus_tag="IXT46_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAQ4947356.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTL"
     gene            complement(574..1008)
                     /locus_tag="IXT46_001436"
     CDS             complement(574..1008)
                     /locus_tag="IXT46_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAQ4947357.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(1108..1956)
                     /locus_tag="IXT46_001437"
     CDS             complement(1108..1956)
                     /locus_tag="IXT46_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4947358.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            2345..4111
                     /locus_tag="IXT46_001438"
     CDS             2345..4111
                     /locus_tag="IXT46_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAQ4947359.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            4213..5472
                     /locus_tag="IXT46_001439"
     CDS             4213..5472
                     /locus_tag="IXT46_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4947360.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            5619..6920
                     /locus_tag="IXT46_001440"
     CDS             5619..6920
                     /locus_tag="IXT46_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4947361.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            6923..7774
                     /locus_tag="IXT46_001441"
     CDS             6923..7774
                     /locus_tag="IXT46_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4947362.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            7787..8602
                     /locus_tag="IXT46_001442"
     CDS             7787..8602
                     /locus_tag="IXT46_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAQ4947363.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            8753..9919
                     /locus_tag="IXT46_001443"
     CDS             8753..9919
                     /locus_tag="IXT46_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4947364.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            10149..10796
                     /locus_tag="IXT46_001444"
     CDS             10149..10796
                     /locus_tag="IXT46_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAQ4947365.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            10880..11824
                     /locus_tag="IXT46_001445"
     CDS             10880..11824
                     /locus_tag="IXT46_001445"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAQ4947366.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            11959..13410
                     /locus_tag="IXT46_001446"
     CDS             11959..13410
                     /locus_tag="IXT46_001446"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAQ4947367.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            13431..14267
                     /locus_tag="IXT46_001447"
     CDS             13431..14267
                     /locus_tag="IXT46_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAQ4947368.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            14267..14926
                     /locus_tag="IXT46_001448"
     CDS             14267..14926
                     /locus_tag="IXT46_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4947369.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            15052..15741
                     /locus_tag="IXT46_001449"
     CDS             15052..15741
                     /locus_tag="IXT46_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947370.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            15747..16703
                     /locus_tag="IXT46_001450"
     CDS             15747..16703
                     /locus_tag="IXT46_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAQ4947371.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            16747..17259
                     /locus_tag="IXT46_001451"
     CDS             16747..17259
                     /locus_tag="IXT46_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4947372.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(17515..18063)
                     /locus_tag="IXT46_001452"
     CDS             complement(17515..18063)
                     /locus_tag="IXT46_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4947373.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(18152..19333)
                     /locus_tag="IXT46_001453"
     CDS             complement(18152..19333)
                     /locus_tag="IXT46_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAQ4947374.1"
                     /translation="MSYLLGIIGLFVTLGLVFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(19569..21077)
                     /locus_tag="IXT46_001454"
     CDS             complement(19569..21077)
                     /locus_tag="IXT46_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAQ4947375.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            21236..21427
                     /locus_tag="IXT46_001455"
     CDS             21236..21427
                     /locus_tag="IXT46_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947376.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            21630..22547
                     /locus_tag="IXT46_001456"
     CDS             21630..22547
                     /locus_tag="IXT46_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAQ4947377.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            22540..23613
                     /locus_tag="IXT46_001457"
     CDS             22540..23613
                     /locus_tag="IXT46_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947378.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            23761..24279
                     /locus_tag="IXT46_001458"
     CDS             23761..24279
                     /locus_tag="IXT46_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947379.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            24260..24652
                     /locus_tag="IXT46_001459"
     CDS             24260..24652
                     /locus_tag="IXT46_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAQ4947380.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            24728..25663
                     /locus_tag="IXT46_001460"
     CDS             24728..25663
                     /locus_tag="IXT46_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAQ4947381.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            25796..26575
                     /locus_tag="IXT46_001461"
     CDS             25796..26575
                     /locus_tag="IXT46_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAQ4947382.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            26568..26885
                     /locus_tag="IXT46_001462"
     CDS             26568..26885
                     /locus_tag="IXT46_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAQ4947383.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            27129..28739
                     /locus_tag="IXT46_001463"
     CDS             27129..28739
                     /locus_tag="IXT46_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4947384.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            28896..29744
                     /locus_tag="IXT46_001464"
     CDS             28896..29744
                     /locus_tag="IXT46_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4947385.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            29975..30454
                     /locus_tag="IXT46_001465"
     CDS             29975..30454
                     /locus_tag="IXT46_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947386.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            30487..32715
                     /locus_tag="IXT46_001466"
     CDS             30487..32715
                     /locus_tag="IXT46_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAQ4947387.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            32844..34487
                     /locus_tag="IXT46_001467"
     CDS             32844..34487
                     /locus_tag="IXT46_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAQ4947388.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(34560..35105)
                     /locus_tag="IXT46_001468"
     CDS             complement(34560..35105)
                     /locus_tag="IXT46_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAQ4947389.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(35128..35613)
                     /locus_tag="IXT46_001469"
     CDS             complement(35128..35613)
                     /locus_tag="IXT46_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4947390.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(35603..36415)
                     /locus_tag="IXT46_001470"
     CDS             complement(35603..36415)
                     /locus_tag="IXT46_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAQ4947391.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(36554..>37665)
                     /locus_tag="IXT46_001471"
     CDS             complement(36554..>37665)
                     /locus_tag="IXT46_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAQ4947392.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        12353 a         6810 c         7434 g        11068 t
ORIGIN      
        1 tcagagtaac ttctatattt ccagctgtag cttttgaata cggacacact ttatgcgctg
       61 cctctaataa ttcttgcgtt tcttccagag aaagaccttc gatagatcct tcaatctcta
      121 cacctaagac aaagctcgtt tcactttctg aataaaggga aacttgtgca ctgacagtag
      181 aagccccaga gatatttttt tgctgtttga tcaattctaa tgcactgtta aaacatgcac
      241 tgaaaccagc tgcaaacaat tgttcagggt tggttgcatt ttcgacgcgt ttaccaggag
      301 ctgcaatatt caattcgaat gtacgatcgg gattatgcac ttctccagag cgtccgcctg
      361 tgttgatcat tttcgtagaa tacatttttt tcataaaatt accaccttta attatatttt
      421 atacaattga attttacaca atataattgt ggaaagcaaa gaaatggatt ggcataagat
      481 aaataagaga aagcacatga aacagacgcg ctttctcgaa tagcaaacat atacaaaaaa
      541 tatcagagac aaaaaataat ctcatcataa acattacata tatttctcaa aaagttgttt
      601 tctttcttca aaaattactt cacgatggac ctgatgaagc atccataaat aaccaaaagg
      661 atctctgaac attgagttag tcacaccaaa gtccatcatt tctgtcattt cttgaatctc
      721 tacacagcca tttcgtaatg ctttattatg tgtgtcctcg atatcagaga cgatgatatt
      781 gaaccagatc gtatttggat gttcagcagt aggagcagtc aaaccaagag acgtgttttc
      841 atccagcata tggaatctcg taccatacaa ggtaaaaatg acttcattat tgcctctagg
      901 gtaatctgtt gcctcaatca gttgtatttc atcaaagatt gtttgataca gttctagtgc
      961 tttcaaacta tcatttaata caaaatcgat ttccgttcct ttatgcataa agatctcctc
     1021 tccttttcag tcgaacagtt actagattct tttattatac cagctaaaga aaacgcattc
     1081 aaaaaaatag cggatttact taccaactca ttcgattgga tgataagtaa atccgcgtcc
     1141 cattacttct gctacgctgc tgacaatgac aaaggcactt ggatcgattt cttctatcaa
     1201 tggtttcatt cgggaaaatt catgatcagt cacaacgatc aataaaacct cttttgactt
     1261 tcgattatac ccgccttttg cctctagcag ggtaaggcca cgtccaatct cagcacttaa
     1321 gcgaaggcgg atgtcttcca aataatgttc actcatgacc ataacagatt tctttcgatt
     1381 gatacctgtt tcgatataag tcatgacaat tgaagtgatt gcaatagata aaatagcata
     1441 aagaaactct tctattccaa aaataaacag attaagagaa acaacgaatg cgtctgtaaa
     1501 aaataagcca atcgaagtat tcaagtggaa atatttttta aaaatgaggg gagggatcgt
     1561 cgtaccgccg ctagaagagt tgtttttata taaaatcgca actcctaaag caaaaatcgc
     1621 acttccaaaa atgacagaca acaaccgatc tgaagtaatc attgtttctg gaactattgc
     1681 aatgattaaa ggaaaaacca agcttccgaa aagtacttta aaaaagggtt ttttacctaa
     1741 aaatagaaga gctagtacca acataacgat attcaacact aaaataacta tagctcggtc
     1801 aaagcctaaa gcagcttcca gtaatattcc tagaccgctg acacctccag cagcaatatg
     1861 atgaggccct aaaaacatat tgatagcgac tcctaatatg aagagggcaa aaataatctt
     1921 aatgtatgtc catataaatt gtctcgtttc tttcatttat tcacttcctt aattcattaa
     1981 taatactctt atcttattat aacttacttt tcaccttaag ttaactttaa ttaataaaaa
     2041 aattaggcta gtctaaatta ttatgtttca ttcttctaga atatacttct acgccaaaaa
     2101 ctgttaaaaa acttttactt tagaaaattg gagaaattga tcgcttaaga taaattcagg
     2161 acactaaata gtacaggaag tagactaaaa cttttaaaag ttttaagtct atctatttgg
     2221 caagtttaaa aaataaaaat tcggtatcaa aaaactgtta ccgataacat ttttgaaagc
     2281 gttgtctttt gcttctctat cacttatagt gatgacgtca tattaaaaca caaggaggaa
     2341 atcaatggat acagctgcaa tttatcatcg accggaaagt gaatatgcat ttctatatac
     2401 gaatacaaga tttcgtattc ggcttcgtac taggaaaaat gatatcaaaa aagtatatgt
     2461 gctatgtgga gatccatata ccataacaac tgaaaaatgg tatcaaaaac aacgaccaat
     2521 gaaaaaatgt ctaagtacca atgttcatga ttattgggaa attgaagtga cgagcgaaac
     2581 aagtcgctta cagtatgcgt tccatgttgt tggggaagat aacacggact gtttttacgg
     2641 tgatcaagga atttttcctt atcgagaaaa tgtgattact gaaccaaatt tttattttcg
     2701 aataccttat tttcatcaaa tcgatcgatt cactattcca gaatgggtaa aagaaacagt
     2761 atggtatcaa atttttcccg aaagatttgc aaacggggac aaagcaaatg accccgaaca
     2821 cactttacct tggggaagta aagatccaga ccgagaagac tttttcgggg gagatttgca
     2881 aggtgtgatg gatcatttgg attacttgac ggaccttggc atcaatggca tctatttttg
     2941 tcccatattt aaagccacat ccaatcataa atacgatacg attgattatt atgaggtgga
     3001 tcccgctttt ggcgataaaa aacttttaaa aaacttgatt gatgaagcac ataaaagagg
     3061 gatacgtatc atgttcgatg ctgtattcaa tcatatgggt gtccattcac cacagtggca
     3121 agacgttctc aaaaacggag aaaaatcgat ctataaagac tggttccaca tccgtttttt
     3181 cccagtagat tcttatcaga tgactgactt accagaaact gctgaaaata tcccatatga
     3241 tacttttgct tttactccat tcatgccgaa actaaataca gcaaatccag aagtgcaaaa
     3301 atatttgctg gatatcgcaa cttattggat aaaagaattc gatattgatg gatggcgtct
     3361 tgatgttgct aatgaagtcg atcatcattt ttggaaaaaa ttcagagaag cagttacaga
     3421 aatcaaacca gacatctata tccttggaga gatttggcat tcctctcaag cttggctgca
     3481 aggggatgaa ttccatgcag tgatgaatta tgcatttaca gattcgatta aagattattt
     3541 tgcaaaaaag aaaatcacag cttcacaaat ggtcagtgga atgaatcatc agcaaatgct
     3601 ttacagagat caggtgaacg aaggaacatt caacttatta gattctcatg atactgccag
     3661 gatcttgacc ctttgccaag gtaacaaaga attgatgaag tctgtgatgg cctttatgtt
     3721 tcttcaaaaa gggtctcctt gtatctatta cgggacagaa atagggatga ctggtgaaga
     3781 tgacccggat tgccgcaaat gtatgatatg ggagaaggag gaacaagatc tagagctatt
     3841 cggttttata aaagaacttg tttctctaag gaaacagttg tctaagatta tttctgaagg
     3901 ttctactcag tggctaatag taaatgatcg tgaagataag ctctatttca cacggaaact
     3961 agagggacag atcatctatg tttactttaa tcagtcaaaa gaaccttggg tagtagaaca
     4021 ggaaaatgag gtgattctta gtcaaaattg tcagttgtta gaagacggga aagcagagat
     4081 acgacaatac ggatttttga tcatgtgttg aaaactgtta ccggtaacaa caagaaagcg
     4141 tttgcaaatg aagatttgtg cccattataa taagggtgta acagcacgtt gaatacaaag
     4201 gaggaaatga agatgaaaaa aagaagtgtg aaacagttgg gtttagggtt aatctcttta
     4261 ggaatcttag gcggattagc ggcttgtggc aatggtaact cttcagcaga aggggaagcc
     4321 gatgaaggaa aaacgttaac agtttccgtt gattctggat ataaagatta tataaacgaa
     4381 ataaaaaaca ctttcgaaaa agaaaacgat gtgaaaatca agctagtaga aaaggacatg
     4441 ttcgatcagt tggaatcatt agcgttagat gggcctgctg gaaagggacc tgacgttatg
     4501 atggcagcat atgaccggat cggtgcgtta ggacagcaag gacatctggc ggaagtaaaa
     4561 ctgggaaatg aagcagctta cgatgaaaca gacaaagccc aagtgactta tgatggaaaa
     4621 atctacggag aacctgcagt aatcgagacc cttgttttgt actataacaa agatttagtc
     4681 gatacagcac catcaacgtt taaagatttg gagaatctat ccaaagacag tcgttttgct
     4741 tttgagtcag aagcaggaaa aaatacagga tttttagcta aatggactga cttttattat
     4801 tcctatggtt taattgcagg ttacggtggc tatgtatttg gtgatgatgg cacaaatcct
     4861 tcagatatcg gtttgaataa tgcaggtgct gtagaaggaa tctcttatgc aacagattgg
     4921 ttcaaaaatg tttggccaaa gggaatgcaa gacataaaaa gtgcaggaga cttcgccagc
     4981 cagcaattca tgtccaataa aactgcagca atcattgacg gtccatggca agcgcaaaca
     5041 tacaaagaaa acaatatcaa ttatggtgta gccaaaattc ctactctaaa taatggacag
     5101 ccttatcaac cgtttggcgg aggaaaagga tgggtagtca gcaattatgc taaaaacaaa
     5161 gacctctctc aaaaatggct tgattatgta acgaatcagg aaaatcaaga aaaattcttt
     5221 gaaatggtaa atgaaatccc tgcaaaccaa caagctaggg aaacagcaaa ggctaaaaac
     5281 gatgaattaa caacagctgt gattgaacaa tatgaaacag ctcaagcgat gccaaacatc
     5341 ccagaaatgg gcgaagtttg gacaggtgca gaaaacttga tgttcgatgc agcatcaggt
     5401 tcaaaaacac caaaagaatc cgcagatgaa gcagtaaaaa caatcagtga agccatagaa
     5461 caaaaatact gattaaaatg ataaccgtcc atttttataa aaaatggaac aggtgcttca
     5521 gataaaagtg gcaagagcga gatggaaaat tatcttgctc ttgttgccat tatcttaaaa
     5581 gcagtttgcg gtttagcaag tttagagggg gcattcagat gcagcaagat aaaacaagca
     5641 atatcaacga aaaaaaaatc acgctttgtt cacttattcc agggatgggg cagtttgtaa
     5701 atggccaagc ttttaaaggt atcgtttttt tcgccatatt cgtcctattc attggtcaga
     5761 tgcttctggg cggatttcat gcattggtag gattggttac tttgggaagt ataccaatgg
     5821 aagatcattc attatttatt ttgattgaag gcactttgca attcatcatt acaatcattt
     5881 tcttgatttt ttacggtttg aatcttttag acgcttatcg agtagcgaag atgcgtcaag
     5941 agggcaaaaa aatcaatcgg acgatgaagg aagtcataca taatataggt gatgaaggtt
     6001 ttccttatct attgacactt cccgcttatc ttctcatgat ttttacgatc attttcccag
     6061 tcctagttac attgttcact gcatttacta attatgactt caatcatatt ccaccagcca
     6121 gtttaattga ttgggtaggg gctaaaaact tttttagtat cttcttttta agctcatatc
     6181 gtaatacttt ttttgcagtc ttttcgtgga ccgtgatttg gactttatgt gcaacaactt
     6241 tgcaaatcac ccttggtatt ctcacagcgg ttgttgctca ccagaaattt attaaattca
     6301 aacgtatttt cggtatcatt ttcttattac catgggcggt cccagctttt attactatca
     6361 tgagtttttc gaatatattc aacgatagcg taggtgccat caatactcaa gtgattcctt
     6421 tcataaacca gcttcctttt gtagatatca gtgcaatctc ttggaaaacg gacccgaact
     6481 ggacgaaagt agcaattatc ttagtgcagg gctggttagg atttccctat atctatgtga
     6541 tggttacagg aatcttacaa tcgatttcag aagacttata tgaagcagca aaaatcgacg
     6601 gagcaaatgc atggcagcgc ttttcaaaca tcacgcttcc tgctgtcttc ctagtggcag
     6661 cgccaacatt tattacacag tatacgggga atttcaataa tttctccatg atctatctgt
     6721 ttaacaatgg cggtcccgga agcgtaggcg gaggagctgg ttctactgat attcttattt
     6781 cctggatcta taaacttacg actggaactt ctccgcagta ttctatggct tcagcaatca
     6841 cgttgattat ctccgtcatc gttatctgtg tgtcattgct ggtatttaaa aagacaaatg
     6901 cgttcaatat gggggattaa caatgaaaaa atttcattcg agtgctcgat tccaaaaacg
     6961 actttctcac ttttttactt acttttttct tttaatactg tcagtcatta tcatctatcc
     7021 gcttttgatc acagcaagta ctgccttcaa gtcaggaaat attgcagctt ttagtttaga
     7081 tctttcaagt gactggactt taggaaactt tactcggcta ttcagtgaaa cactttacgg
     7141 gacttggtat aaaaatacat tgatcatttc tgtcctaaca atgatcgtac aagtgactgt
     7201 agtaactttg gcgggctata cttatagtcg ctatcgtttt atcggccgca aatcaagttt
     7261 gatgttcttt ttagtgattc agatggtacc gactatggca gcattgactg ccttttatgt
     7321 catggctttc ttattagaag cgctcgataa gtactggttc ttgacaatga tctatatagg
     7381 cggtggaatt ccaatgaata cttggctgat gaaaggatac tttgacactg taccaataga
     7441 tttagatgaa tctgctaaac ttgatggggc agggcatttc aggatttttt tccagattgt
     7501 attaccgctt gtcaaaccga tgctcgccgt tcaagcatta tgggctttta tgggaccttt
     7561 tggggatttc atgttagcta agttcctgct tcgaacacct gaaaatcaga ctgttgctgt
     7621 cggcttacaa acatttattt ctgatgtgac aaaccaaaga gtctctcttt ttgctgctgg
     7681 ggcaattttg attgcactac cgatttgtct attattcttc tttttacaaa agaactttgt
     7741 taccggcctg acatctggcg gaacaaaagg ataggagcag agtatcatgc aaacatttcc
     7801 gttaaactat ttttccgcat tacgtacgcc aactcaagtg tttgcgggac gcaaactatt
     7861 atcatggcct aaatttttct tgatatttgt atttttagtt tccttgatgg tcatgcctgt
     7921 gactcttttt tatgccaatc agatccaagc gattccatta gaacaatttc tatccgttca
     7981 ttcgctgatc gatgaacaag gaacccaaaa attttctgaa cttgaattat ctgaaactgg
     8041 gttacaagca tcgcaacaaa cgatagctgt gacccctgaa attttggtag gtgtgtcttt
     8101 atctgagaaa caacaatccg atcatggaac ttttattgat tttgagaagg aacaatgggt
     8161 gatccaacaa aaggataaat ctggtatacg ccgctatacg atgaattata gcccatcttt
     8221 ccaaccagat tctgtacgta cgcccgaaga tttccaacga tttttagaaa gagaatttta
     8281 tgccagtaat cgtccaacaa tcattttatc ttatagttta agtcttggtc ttgtcctatt
     8341 tgtcatgacg agtctcattt tattcggggc ttcctttttc ttgtggatga caagaaaaag
     8401 ccaactttca tccattcata cattcaaaga gagtgcaaat ttgatgctga atgttatggg
     8461 aataggttcc atggcagcag cagttgtagg gtttatccac tttgacttta tcttgatgct
     8521 aagtgtccaa acaacgataa ctgtcttgct gcttttatgg gtttttgtca aaacaagatt
     8581 caaagataag cgtgtcgaat gacaagttta agcgatttat gcgacaatga atgtgaaaaa
     8641 aatgaaaaat aaagtagttt ttgaaaaatt tctgaaaaaa ttaaacttct tagttgattc
     8701 ttttcttttt tagtattaac gtaatagggt agttttttta aggaggaaaa tcatgttaga
     8761 gaaaacttta tacaatcaat tattttcacg ttctttctcg ctccctgtcg aagtaaatta
     8821 ttgggacggt acaacgaaac aatacggaga tacggacact cctccccaaa tcaaaatcaa
     8881 tatccatgaa gaaatcccaa tgaaagagat tacaagtaac gcatctttgg cactaggaga
     8941 agcctatatg gatcatcgaa tcgagatcga gggaagtatc caagcattga tcaacgatgc
     9001 ttatcagcaa gcaaacagct ttttacgagg aaaagattat ctaaaatggc tgccaaagaa
     9061 agaaaaacat acgaaacaaa aaaacaaaga agatatccat gcgcattatg acttaggtaa
     9121 cgacttttat aaactttggc tagatccaac tttgacttat tcttgtgctt atttcaatac
     9181 acctgaagat acgttggaac aagcacaaat caataaagtc catcatatct tagacaaact
     9241 ctttatcaaa gaaggcgaaa cgttgcttga tatcggttgt ggctggggaa cattgatgtt
     9301 cactgctacc aaagagtata atgtcaaggc aactgggatc acactaagtg aagaacaata
     9361 cgatttgatt accaaaagaa taaaagaaga acatttagaa gataaatgcc gtgtattatt
     9421 aatggattac cgcgaactaa aaggcgaaac gtttgatcat atcacaagtg taggtatgtt
     9481 cgaacatgta ggttctgaaa atcttgaagg ttatttcaaa gtggtaaaag atttattgaa
     9541 accaaaagga acagctttga tccatggaat cagccgacaa caaggcggtg cgacaaatgc
     9601 ttggatcaat aaatatattt tccctggcgg ttatgtccct ggtgttactg aattagttga
     9661 taatattaca aaaaacgatt tgcaactgat tgatttggaa agcttacgtc gtgactacca
     9721 attgacatta gaacattgga caaagaattt tcatcaagtc caagatcaag tcacgaaaga
     9781 aatgggtgat tccttctatc gaatgtggga tctatattta caagcttgtg cagcttcatt
     9841 tgaatcaagt aatatcgatg tgattcaata tttgcttgtt caacctggaa acaatgacat
     9901 cccaatgcat cgtgcataat tgaggcaaaa gtactgttta aagactattt aaaaagaagc
     9961 taagttttat gatgctccag aagtgaactt ttttgtctaa cttctaggat tgtctctaaa
    10021 gcttagtttc tttttcttta tattttcata ataaaagttt ggttctttaa tttttaaaca
    10081 tgacagaaaa ttttttcttc gttatacttg taatagaata ctattttata acaaagggga
    10141 tcgaatcaat gaaaaaaact gttatttata ctagtttatt tgcagctttg tttttagctg
    10201 cttgtcaatc aaataccaat caaggcacat ctgggaatac gtcttccagt agcgaacagc
    10261 gctcttcaca ggtatcggac tcctcaacaa aagcaagcac atcttcgtct agccagacaa
    10321 aaagttctag tgaagcaagt actcagtcag atatcaaagt gtctgcagct cgtgcgatcg
    10381 aattgttcca agataaatac ccagatactg caattactag tttggaatta gatagtgatt
    10441 ggggatctta cttctacaag atagaaggtg tcgatgatca aaaagaatac gaagcaagaa
    10501 ttgatgctca aaatgaaaaa atggagacag agaatccaga aactctagat cgagatgaac
    10561 aaaatggtca aaagaaaaaa gaagatggtc tggatgttga taaattgatc acgattgagg
    10621 aagcagcaaa aatcgccgtc gacaaagtag gaagcggtac ggcaacagat tgggatttgg
    10681 ataaagattt aggtactact tattgggaag tcaaagtaaa agacggcaat caaagtacat
    10741 cagtcaagat caatagccaa acaggcgaag tactgtcaac tgaacaagat gattaagaat
    10801 ttcttcggaa aacaagagtt gatttttctt ttagtcatga tacactagac aaaataactt
    10861 gtttgaagga gcgatttact tgagtttaga aacgaccttt gccaatcata tctttgccaa
    10921 tcctttgatg aatgcatctg gtgtccactg catgactacc caggaattag atgaactggc
    10981 tcattcagaa gcaggagcat ttatcactaa gagctgtacg atcaatgaac gaaaaggaaa
    11041 tcccgaacca cgctattttg atgttccttt agggagtatc aattctatgg gacttccaaa
    11101 cttaggtttt tcttattatc tagagtatgc tcttgcgtat gaaaaagtgc aggaaaacca
    11161 aaatcaaccg ttattttttt ccattgccgg gatgagtgtc caggaaaact tggaaatgct
    11221 tgagaaaata gaaaaaagtg ggtttaatgg gatcactgaa ttaaatttat cttgtcccaa
    11281 tgtgcctgga aaaccacaac tagcttacga ttttgaggcc acttatgaaa cactgaaaga
    11341 agtattcagc atcttttcta agccgctagg aatcaaattg cctccttatt ttgattttgc
    11401 tcattttgat cagatggctg atatcttgaa tcagtttcca ttgacctatg tcaatgctat
    11461 caacagtgtg ggcaatggtt tgtatatcga tacagaacaa gaagcagtag tcatcaaacc
    11521 aaaagaaggg ttcggcggca ttggcggaga gtatatcaag ccgactgctt tggcgaatgt
    11581 tcgcgctttt tatacacgtt tgaaaccaga aatccaaatc attggtacag gtgggattcg
    11641 gacaggacaa gatgcatttg aacatctgct atgtggcgca agcatgttac agattggtac
    11701 cgagcttcat aaagaagggc cggaaatttt ttctagaatc ataaaagaat taacgcagat
    11761 tatgtcagaa aaaggatata cgtcaattga cgaatttaaa ggcaaattac gcaccatttc
    11821 atagcaaaga gacgaaggtc atgattgatc ttcgtctttt tttataaaaa acactcgtct
    11881 gttcattcct gtgcaagcgt actcattgta tgttagacga acttgtggga aaataacaga
    11941 ggcaaaaagg aggataatat gaatgatgca acagaattag caaaagagct taaagaaaaa
    12001 gaatttagtt ttcaagaact agttacggat atacagaaaa aaataaagaa gcaaaatcat
    12061 gaattgaatg cgtttgtcgc gcttgaacca ttcgagagta attcccacga gctattgatt
    12121 ccccagtcag aaaaagggcc attggctggt atcccatttc ctttaaaaat gctcggtcaa
    12181 gaaaaaaagg gatggctagc tacttcagga tctcgtttat ttgaaacaca ccgagcttct
    12241 catacatcta attatgtgcg gcaagcagaa gcgataggtc tagttccttt tggacaaacc
    12301 aatgcgccag agtttggttt caaaaatatt acagacccag tcatctatgg cccagcaaga
    12361 aacccttgga accttgaatg tacaccgggc ggatcaagtg gaggagctgc tgctgcagtt
    12421 tcatcaggaa tcgttccttt agctggtgct agtgatggcg gtggttctat tagaataccc
    12481 gcttcgtttt gcggattgat tgggctgaaa ccttcgcgag ggacgatgcc agttggtcca
    12541 tatgcttgga gaggatggca aggagctgct attgatttcg gcttgacagt ttctatgaga
    12601 gacacggagg ctttatttta tgggatgaga agtatccatt ccggtgcgcc atatcaagta
    12661 tcgccagttg agtggcaaac acatccaaga aaaaaacggt tgaagatagc tttttgtgtt
    12721 gattcaccga tccactcaca gattagtgaa gaggcagtac ttgctgtaaa aaaagctgta
    12781 gatttccttg gaaaagaagg gcatgatttg acagagattc cttacccact agatggtcgt
    12841 aaactgatca cgtcttatta tcagatgaat ggcgcagaaa cagcagcaat gatccgctcg
    12901 attgaaacag gcatccagcg agctgtcaga aaagaagaac ttgaacccat ttcttggact
    12961 ttgttccaat atggtcagaa gctctctgcc gctacttaca tcgattctct gcatgtatgg
    13021 gatgaagcag caattgtcat ggaaaaccta catcaagaat acgatctatt cctttcacca
    13081 acgactgcat ttaccgcccc taaaatcagc gaagatttgc aaagtgatgc gataagagca
    13141 cagatggaac acatcagtga ttgttctgaa gtagaaggtt tagacgttgt ttcttccatg
    13201 tttgaggaga gcttgaagat cacaccttat acacagttgg ctaatctgac tggacaacca
    13261 gcaatcagct tgcctactca tttgacaaaa gaaaacatgc ctctaggaat ccaatttatg
    13321 gctgccagag gaagagaaga tttgctattt caaatcggct atctatttga agcaaatcat
    13381 cagttccatt taccaaatcc atggaaatag cagaaacaag gagaagaaga atgaagaaaa
    13441 aaagattgtt tgctctaata actagtgcct tttttatttt aagcgcttgc ggtacagctg
    13501 ccgctaatca ggaagataac agctggagta atgtagaaaa aaagaaagaa ttagtagtag
    13561 cgacttctgg cacactgttt cccgcatctt attataatga tcaaaatgaa ttagttggtt
    13621 atgatgtaga tttggcaaaa gaggtggcta aacggttaaa tgtcaaaatc tcctttaaag
    13681 aatacaacgt ggatggacaa atcacttctg tttcaaaaag agaatcagat tttgctgcga
    13741 acgattttgg tatcacaaaa gaaagagaaa aaaaattctc cctttcagag actttcaaat
    13801 attcatttga cagtatgatc gtacgaaaaa aagatgattc aggaatccac tcacttgaag
    13861 atcttaaagg gaaaaaagca gctggcgaac ccaatactag ctatatgcgt ttagcggaaa
    13921 aacacggagc taaattagtc acatatgaca atgccacgaa tgatcagtat ttaagcgatg
    13981 tagcaaatgg tcgaacagat gttattctaa atgattatta tctgcagaaa atggccgtat
    14041 ctgctttacc agatatccct gtaaaaatac tggagaacgt ttatttcaat gaaaacgaaa
    14101 gtggtttttt attgaaagaa ggaaatgatg ctctgaaaaa gaaaatcgat ggcgtattaa
    14161 aagagatgaa agaagatggg acgacaaaga aaatatctga aaaatatttt caaactgatg
    14221 tttcagtcaa accgaaagaa acgatggctg agtcggtgag tgagtgatgt actttcctct
    14281 aattgatttt tccctcatgt ggacttcact tcctttcgta ctgcaaggct tggtatacac
    14341 attagggatt ggcttcgtgt cgtttctttt aggaaatctg gtagggttgc ttttgacagt
    14401 tttaggtctt ttggattggc tgcctctgaa tgtatttatt cgtttttatt tatcgttctt
    14461 tagaggcatt cccgcactag tcctgctgtt tctgttatat tttgggttac cttatcaatt
    14521 aagtgcctta acggcttcag tcatctgctt tacgattacc agcagtgcat ttattggtga
    14581 aatctatcga ggatcactag caggcgtttc ttcaggtcag tgggacgctg gtttagcttc
    14641 tggtttttct ttctttgggg tattgaaata tatcgttttg ccgcaagctt ttcgaatctc
    14701 agtaccggca ctcagtaacg tagctatgga tctagtgaaa ggtacttcgt tagcagcaac
    14761 aatcacagtg ccagaaatat ttcaaaaagc aaagatcata ggcggtcgga cattcgatta
    14821 tttttctctc tatattttag ttgcactgat ttattgggtc atttgtatcg ggatcgaaaa
    14881 agtgcaacag tatttagaaa aacgttctat gcatcagtca atctgaaaaa tagaaatggt
    14941 gctagcgtgg ctggcaccat ttctattttt tgtttcttgt atattctgcc tagtatttta
    15001 aaaccatttc atgtaaaatg taaatcgaaa atatgttcgg aggtagaaaa catgaagacc
    15061 ccgctaacca tcgaaataga atcctcgtta taccaatatt gcatcgagca aggcggcttg
    15121 gttgtagaag aagtcacgat gcctgatgac caaggaattg tagatacgct tagctgcttg
    15181 acaaaatttg atggaagccg agaatggcga tgctatgagc tgaaagtgac aaaagcagat
    15241 tttcgctcta cagccaaact gtcatttgtt ggacattata attattttgt tttaccaagt
    15301 aaactatatg aagaagtaaa aactgaaatc cctacaggaa taggtgtttt agtgtatcgt
    15361 ccgtacacgg ttgaagagga gatgcctgcc tctggtacat ttctgattgc gaaaaaagca
    15421 gcaaagaaag agcttgctgt accggaagaa gctttgacaa accgcttcat ggcttcttta
    15481 ttcagggaag taagaaaagc aaagcaaatg gagcgaggcg taaaatattt tccaacagat
    15541 caattgtaca aagaattgaa aagacgttca gaaaatcaag atccattttc taacgaacga
    15601 tattatgaac ggtttttaga ggaaatagct agtcaggcaa tcaatgagtt gcaagaagaa
    15661 gttatcgcgc ttcagcatga ttatgaatat ttgaggcaac aacagcagat ccgtcggttg
    15721 cctacagagc cattggagtg aaaaatatgt actatcctta tttaagagga aaacaatttg
    15781 acctattagc attaaaagaa gcactgtcgc gaggattgct ctccaataaa atccaaccag
    15841 tgatcgaacc agtacgtgat tccgctacgc ttaaaaatgt gatcgaatta tttcaaaaaa
    15901 agcaccatcg aatcgctgtg atccaaaatc cccaagtagg acaattcaaa ttattcgatc
    15961 agcatgtgca cagttggaca gtcaaagaaa atagctctgt cgtccctgca cagatcttaa
    16021 cgccagaaaa tctcagtgaa gtactggatt cacctccagc gtttcttgtt ttcgatggac
    16081 agcactaccc aaaagataca gaggtgtgga aacagttggc aggagttgat tcgaaatttt
    16141 tgataccaga tactagtcgc tttcgcatct ggctgcccga aaacaaaatt gtgatccgtg
    16201 actcttttca aacgagaaag catgttgaaa gttatgcaga taaaacagat gactttttta
    16261 gtgatgacta tctttttttc cacgcagacg gatatattgg attttctgat ttcacgatcg
    16321 aaggtagccg ttatttcgat aaagggttcc ctagccgagc gcttgctatc catctaacgt
    16381 atattgatgc ttacggcaat atacgcgtga aacattttgt ctctgacagt aacgactctg
    16441 ctaaagacca agcattgaag tttcttgaag caggagataa aatgaaaaaa tggatcatgc
    16501 gtcaccatca tcaactcttg attacttcag gaatgattga attattggct ctttaccagc
    16561 aacaaaaatt ccctggactg ggagtgttga aaaagtggtc acttatgcat catttggaac
    16621 ttattagtca cctgctagat catccaaaag attggcttaa atattattca aaagttcagg
    16681 aactatatga agtgatccaa tgattagata atgtaaatga aaaaggaata gaaaagagga
    16741 aactggatgt atattcggca aacaaggaaa gaagaagtag aagaagtggt agaaatcatt
    16801 aatgccgcag cggatttcat tgcttcgcaa ggctctcctc aatggcaaaa cgggcagaaa
    16861 ccaacaaaag aaacgatttt gaacgatatt gaaagaaaag aaagctatgt attaatagtg
    16921 gaagatcaaa ttgctggaac agctgcatta gtctcaagcg tggatcccgt ttacacaaaa
    16981 atagatggta gttggaaaga atcaactggt ccttatttat cgattcatcg tgtcgcttta
    17041 gcagaaagta ctcgaggaaa aaaactagca aaaccgttct tagaacattt gttgacgatt
    17101 gcagccagca aaaatatcca agatatccgt atcgatactt atccagctaa tgaaccgatg
    17161 gaaaagacca tctattctgc tggattcact tatcaaggga tgattgaatt tccttttgaa
    17221 cacggcgaaa gaaaagcata tcaaataatc atcaattgac tataaaatca tctgagcaaa
    17281 gataaagaca ttaacactac tgaaaaaaac aatcatatga tagccaagag gttgtaacag
    17341 aagtggccag cttcaaaaaa caagaaagaa tttccgaaaa tgcttctcaa atttttgtgg
    17401 aattttagcg tattttacga aatagctgct ttctgaaact cccttcatcg agaggtcgtg
    17461 acatagcttt tgtcacgacc tctcggctta tcctacgagt attattcgat acatttatat
    17521 caataatcct ttttttattt tatctgcagc ttcttggaac gctccatcgt ttgacacgac
    17581 taaaagtgag gggatagctt tcaaacgttt caactgtgct aaatcttcta cataaaccgc
    17641 cagtctggct gaaatctgtt cagatgaatc tccacgtttt ttcaggcgcg attgcaatgt
    17701 ttctttagag atcgtaataa agataggacg gactaccgtc ccgaaatact catataaatg
    17761 ccaaaaacca tttgctgtca aaacggcgta acaatttcct actgtcagtt tctttttaat
    17821 ttctgcttta ctggaaccat atttatgttg agcatattgg tcccactctg caaactcatt
    17881 tcccttgatc atctgattga atgtattgtc agaaacaaaa taataatcct cttgatcttt
    17941 ttccccaggt cttggtgatc gattcgtgta agtaatgatc ttttgttccg gctgaaaaat
    18001 agcttctgcg agtgaagttt ttccagaacc agaaggaccg ataaatacat agcaataatt
    18061 cattgtcatt tctcctttga tgattgaaca agtgaaaaag ctttggaaaa tatttccaaa
    18121 gcttttaaaa gtaactttgc ttttttgtat attataccag caagccagtc acaatagcac
    18181 ttaaaaagct gactaaagtc gctgttagca aaattttcaa tccgtgtttt gcgacaagat
    18241 ttcctttttc ttcatttaat cccttcatcg caccagaaat gatcccgata gaagagaagt
    18301 tggcaaatga aacgaggaag acagatataa ttgctgttgt acgctcagta aaatggaaat
    18361 taccatttgc taattctgtc atagcaacaa attcatttgt aaccagttta gtcgccatga
    18421 tactaccggc atccactgct tctttccatg ggattccgct gatgaaggca agaggggcaa
    18481 agatgtaacc taggatctct tggaaagtga tgccgaatat cccgtggaag atagcattga
    18541 tcatggcaat caaagcaaca aaaccgataa gcatagcagc aaccgtgatc gccacatgga
    18601 aaccatcaag aatgtattct cccaacattt ggaaaaatgt ctgttctttg ttttcttcaa
    18661 tgatcagctc atcttctttt tcttctaata catagggatt tacaattgaa gccagaatat
    18721 aaccgccaaa taagttcaaa acaagggcag tgatcacata tttagaatcg atcagtgcca
    18781 tataagatcc gacgatcgac atagaaactg tagacatagc cgatacactc atggtgaaca
    18841 aacgtttctc agataggaag ggtaattcct tttttatgga aataaaaact tccgattgtc
    18901 ctaaaatagc agaagctact ccattataag attccaattt gcccatcccg ttgattttac
    18961 ttaatcctag accaacagct ttcataaata atggaagaat cttgatatag cgtagaatac
    19021 cgataatagc agaaataaat acaattggca tcaatacgga aagaaagaaa ggtgcacttc
    19081 ctttatttgc tacaccggca aaaacaaagt caacaccttg cccagcaaaa gcaagaagat
    19141 gatcaaacat ttttgccaat acagaaacaa ccgctgtacc aaaagttgta cgtaataata
    19201 cgaaaccaag aacaagctgt aaaacgaaca tcacaattag tggtttcaat ttgattgctt
    19261 ttttgttact gctgatcaaa aaaacaagcc ctaatgtgac aaataaacca ataataccta
    19321 ataaataact caaataatca ctcctattcc aaattccgtt ttattttacc tgttttgcaa
    19381 ataaaatact aatctttagt gaaattttca ttactttttt agagtgaaac gcattcattt
    19441 tccattagaa aataaagcga acaaaataaa aggtttaaaa agtgtaacgt cttagtaaag
    19501 tctataaaaa aacgaaacta tcgattaagc taatagtttc gttttcaaca tttataagta
    19561 aactttttct attggtaata tagattttcg gaagggtaga caggtgcgca ggtaatatcg
    19621 attcctagtt ttttcaatgt ttgttcatca tttttattga ccatcacagt agagtgggct
    19681 tgtgctccct caagttcagc tagtttatca taagcaactt gagcgattgg attcgttact
    19741 gcactgattg ataaagcgat caagacttca ttgatgctta gtgcatccaa agaggaatga
    19801 agtgtctttg atttcaatcc ttgtattgtt tcaagaacta atggtgacaa taaaggaatg
    19861 tcatctgcga tatgggctaa atgttttact gcatttaaga taactgccgc tgacgcatcc
    19921 atcaatgaac ttgtacgccc ggtaatgatg acttcatctg gtaattcgat tgcaatcaca
    19981 gcagaaggat cttttgtagg actttgcgct tgaatcttat ctgcatagtc atgggcaggg
    20041 actaccacgt ttcggtcttc aggacgtaaa ccgacttctt ccataatcag tttgattcga
    20101 ttaactgctt cttcgtcgat caatcctttt ttgaagtcgc attctgtttg gaaataacga
    20161 cggatgattt cttgtttaga ggcttcttgg acaacggtat catccacgat cccaaatcct
    20221 acacgattca cacccatgtc agtaggagat tgataaacag attctttacc agtaattttt
    20281 tcaataatac gtttgattac aggaaatgtc tcaacatccc gattatagtt cacagctact
    20341 ttattgtagg catcaaagtg gaaggaatcg atcatattga catcttttag atcgactgtg
    20401 gctgcttcat aagcaatgtt cagcggatgt ttcaacggaa cattccatac tgggaaagtt
    20461 tcgaacttgg agtaaccagc tgcatgtcct ttttggcttt catgatacag ttggttcaag
    20521 gaagtagcga gctttccact tcctgggcca ggagctgtca ctacaacgat tggtttagtt
    20581 gtttcaatat actcattttt tccaaaacca tcttctgaga cgattttttc tacgttgact
    20641 ggatagtctt cgatttctga gtgtttatag accttgatgt ttcgtctttc tagtttattg
    20701 ataaagactt tcgtggcagg ctgtccacta tagcgagtga taacgacact gttgattaat
    20761 aagccataac cacgtaattc atcgattaac cgcaagatat ccatatcata agtaatccca
    20821 taatcaccac ggatcttatt acgttcaata tctccagcat agacgcaaat cagtatttca
    20881 gcttgatctt tcaatttttg cagcaatttg attttcgcat cttcttcaaa tcctggaagt
    20941 acacgtttcg catgcttgtc gtcaactagc ttcccaccaa attctaaata taatttgtca
    21001 tagtggttca ctcgttccaa aatatacgct gactgctctt caatatattt ttctgaatca
    21061 aaaccaattt ttttcactag gttccctcct taagtactaa agcatttttt catttttttg
    21121 aggattcgtc aactggaaga gcgaaattcc tcaaaaaaac aaagaaaatg gtttaaacca
    21181 acttgtctag atagttattc attggtatga tagtttttga taaggaaggt gctacatgaa
    21241 aaaaagacag aaaaagaaaa acgcatataa acactatatc cgttcgattt ttaccggtta
    21301 tgaaagaatg cttgaagatc ccgaattgga acaattgacg tttacttatc taaacgaaga
    21361 aacgcagcta actcgtgatg agcatcagcg cattcatttc acaacaagag atctgcctag
    21421 taaataaaaa ataagataaa ggtcatcgga ttcgattctg tcctatcaga tggaaagact
    21481 agttgatcga aaaaaaggct gtaccaaatt ttggtgcagc ctgttttatg gagcattgcc
    21541 cgctcttttt tataacaatt ttttacagaa aatggtacta ttgaagtatt aataagtgaa
    21601 aaacagatga gtaagaggag gcaagtagta tgaaagagcc agatacaaat gcaaattatg
    21661 agccagacga actagaggag acgaatgcgg atcaggatac aggacaagaa tcgtcttctt
    21721 tttacgatat caaagaaaaa gcaagcatga atctttccca attattagaa gacttacagg
    21781 cttttgaaaa agctgtccgc gaagaagata tccctgagat ctaccgttta tacaatggcc
    21841 gattgaatga agaattaaaa agaagctcaa atgaaaatca cgagatcgat caattgctga
    21901 tgcgtaagat ccatgatcgt tttttacagg aatttccttt tatggaacaa gtagaaaaca
    21961 tctcgccaac gatgagctat tacaaaatcg gcacttatta ccatgatcgg cccacggtcg
    22021 gtattgatgc aagtctgcca gaaatttttg ttttgcctaa gatcgatgaa gagtgggaga
    22081 aatattccca accggagtca acggactatg acaaaaaaat caatgagcta gacgcaaagg
    22141 tgatcactgc tcagacagaa attgaacgtt tagatgaaca aataaaagaa atcaatcgac
    22201 aaatgactga tttgaacgac aataaaggat tcttgaatcg taaaaaaatc gaggaagaaa
    22261 ttcaagaatt agagaagaag aagcaagtac tatctaatga aaaattaggc tggcttcctt
    22321 atattgagac gcctgaaaca atccagcagc aaaaagaagc attgaagcaa gaagcaagag
    22381 cagaccagct tcgtgcagcc atcgtagaaa aagaacaaag gcaaatcaga cgctatttcg
    22441 gtagcaaaga gggattcggt caagcaatcc atgaattctt gatgaattat cttggcaatg
    22501 agaatcctaa taatcaatct aatgaaggag gttccgagta tgaatgaaca cgatgaagca
    22561 gaatggacaa aaaatgaaga acaaacagaa gatcatgaag aaacgaacac ttcattggaa
    22621 gaacaaacaa gtaatcctct ggatgacaca gaagaaatcc ctatgctaga ggaaacaaaa
    22681 atacacgaaa aagaaaaagt aactccgacg aatacgaata ctgcagaaaa cacccatgct
    22741 tacgaaataa ctgaaaatcc cgggtattta gaaggaaaag agcaagatca tcaagatatc
    22801 gtcagtttga ttgaaacagc ggaagcagaa ttagcggatt tacgtatgag aaaagatttg
    22861 atcgaatcag attttccaca attattagaa tcatatgatc gttttatatt gaatgaagaa
    22921 ccaatctcca cgatcggaaa gacaagcctg atcgaatact tcacgtatga attactgaaa
    22981 ccgttgaatg atattggtct ggaacggtca aattcagctt atgacacatg gaaaacaaga
    23041 catttttcga tcaattatac gttgaatgga caaaacgaat tagtcttttc ctttgtatta
    23101 ccgaccatcg atcaacgata ccaagtggaa tcgatgagtc tcctaaacgt atcaccagag
    23161 acaatggaaa tcaatgtcca agatgaccgg gtgctttctt tgatccgaca ctggtcagtg
    23221 gatcgagtat tctctgcagg gcagatcacg atattcaatc acaaattgaa tcaattatta
    23281 gcccatgcaa gaacacttgg ttttaccgtt aatcagacat tactagacaa tacgaagcca
    23341 cttcgtttga atcttcagag cgaatttgaa ttgacgaatg aagtattgga tgatattttt
    23401 atcgtggcaa tgaaaaatcc atcctacgat atggaaaaga tcaacgaaac tacttatcaa
    23461 gtacgattag ataaaggaca gtctttaacg ataacaacaa acgaaaaaga tcaaacagtc
    23521 ttgtcgatct catctggaga ctacccacga tctgtcattg atttctttat caattacgaa
    23581 ttcttggtcc cattaatggt gagaaagtcc tgattggata agttggatta ccagatgtca
    23641 ttcagataat tctgttccaa aggacttgcg gcagttatcc agaataattg tcacaagtct
    23701 tttctgtatg tactaaatgg acgtgaataa cttgctgatg aaggagggat ttcattagga
    23761 atgtccacaa ataaaatagc acagcttagc ttattgtctg ctgcttgtgt agcaggtagg
    23821 atcgcttttc aatttattcc gaatttccag ccaatgactg ctattttttt atttatagta
    23881 ctttacttaa gcttaaaaga tgcgttaatt gtcatgagtc tttctattgc gatcagcagt
    23941 ttttattttg gtgttggacc atgggtcatc ggccaatgga tcagctatac tgttgttctg
    24001 agtttgtttt caatcgtctg cttgagaaaa acagtgcaaa ggaatctatg gttaaaggga
    24061 gtctgttttt ttctggcggg catggtttac ggaataggta tgaccgtttt tgatacgctg
    24121 ttatatcgtt tgcctcaacc ttggatctat taccttcaag gggtgtcgtt tgatttgatg
    24181 cacagtatag gcaatgttgt gttctttctt gtttttctgc cagtcgtcaa acgtttttac
    24241 aatcattcag gaggaaaaaa tgaaaaaaat aatttatagt ttgcttgcaa tgagtgtcag
    24301 tatactcatt ttgacaagtt gcagtacaac ctatacacaa tcggcttcca accaaaagga
    24361 ggaagtaaaa acatcgcaaa aagcaacaat cacgttacaa gaaaatggtc aaaacttttc
    24421 ggaaaaagaa gtgttcttca aaaaaggcga tgatttactg agtattttga aacgaaattt
    24481 tgaagtcaaa gaagataacg gcttcatcac ttcgcttgaa gggcactcac aggatgagaa
    24541 aaatcaactc tattggatgt ttactgtgga cgggaaaagt gctactactg gtgccaaaga
    24601 gatcaaattg aatgatggac aatcggtcat tttcaatttg tctaaactat aagtttcata
    24661 aaaaactgtt aaagggcgaa tattgccata attcagtgag ttcagttgat gaaagaagga
    24721 aaataacatg gaaaatttta aaaaaagcgg aatgttttcc gtaattgctg ctctaggggc
    24781 taatattcta gttgctatca gcaaatttgt cggctatgca atcagtggca gtgccgccat
    24841 gctaaacgaa agcatccaca gtatcgttga ttgcagcaat cagattttgc tgttattcgg
    24901 tgataaacaa gccaataaag gacagagcga gttgcatcaa tttggtgaag gacgagcaaa
    24961 atactttttc agtacaatcg tcgcaatgat gcttttcttc ggcggtgggg cacttggggt
    25021 gatggaagct tttgaaaagt tgacgcatcc atcccatgaa gtgggtaatc cgatcattgt
    25081 tatagcaata ctgttatttg gtttggtaat cgaaggaagt tcgttacgcg tggcaatgaa
    25141 agaaatcaaa gaattgaata ctgaaaaact ttccacgatg cgctttttgc gcgaaagtcg
    25201 acacagtgaa atactgatta tttttacgga agacttgtgt gctgtaatcg gtttggtctt
    25261 ggctttagca ggaacaatat tgacttatgc aaccgggatt gctgcatttg atgcgatcag
    25321 cggattgctg atcggtttct tgctgatggg agccgccatt ttcctagcaa aagaatttta
    25381 tagtctgatc atcggtgaaa gcgtgacagc aagcgattta tcaaaaatca agttagcttt
    25441 tgaacgtcct gagatcagtc ggctgatcga tataaaaaca gttcatttaa gtccaacgga
    25501 gattttagtt gcagcaaaag cagatatcgt tggtaacaaa gagaatgaag cttactcggt
    25561 catcaatgat attgaaaaaa atatgcgtca gtctcttcct gacaagaaga tgtatatata
    25621 cattgaaaca gataaatatg acccaaatta ttctcgtaaa taaaacgttt attcatgaat
    25681 tgaagcaaaa atgagaaaaa tataatcttg tttttaaata aaacggctac aatttagcga
    25741 atttatgtta caatgagtcc gctgtttatt tgttgtaatt aaaggagata ttttaatgaa
    25801 caaaaagaaa agtgcgccat ggcttcaagc tttgcatgca gtgatgccac tttgtataag
    25861 ctatatacca gtaggattag cttgcggagt attgttgcaa aaagttggat ttgatcctct
    25921 cttatcagga ctgttatcga ttctggtctt ttccggtggc gcgcagtttt tagttgcatc
    25981 tatgcttacg acgcaagcat catttgcaac gacattattg atggttttct ttttagaatt
    26041 acgctataca ttattaggag caagtcttgc cggttttatg aaaaaagaaa agcggacgtt
    26101 tttggctgtc ttttctcaat cactgaatga tgaaaactat gcggtgaact acttaaagtt
    26161 ttcaactgac ccttcctgga ataaaagaaa ggctttatat gtcaattggt tctcaatgac
    26221 tgcatgggcc ggtagcaata tgatcggtaa ttttttcggc tcggtgattc gagtagatgc
    26281 tgaccttgtc cattttgctt tgacggccat gttcattttc atgtttatca tgcagatgaa
    26341 aagcgcacta ctgatcttta caggtttatt ctcaggcgta ttaggggtcg tattcatggt
    26401 attattccaa aatactttcg gattgattgc agcaacagtc attgcttcat ttgccggatt
    26461 tatgctggag aaggcattca aaaaagaaaa agctaagaaa ctaagagacc gcggtaaaga
    26521 tgtcaatgag ccgctcttca acttcccgga acaggaggcc aatcaccatg actaaactat
    26581 atttgctact tttagttgct tgtctgttca tcgtggcata tatcccgcgc ttgttcccga
    26641 tgctttattt tactcatcga aaagtgccat cctggttcag tgactggatg aaatatgtac
    26701 cggtggcatt atttgcggcg ttagctttta aagatgtttt cattactcat gaacatctgg
    26761 atattgcttg gaatatcaaa atagctgcaa tgattctagt agcaggcgtg gcttacaaaa
    26821 cacgttcgat ggcgttgtca gttttgacag gacttgcgtc tgtctttttg ctgtctatgc
    26881 tttaaactgt tttattttat taaaaacaga gattgcgaca taagttgttc aaactgatct
    26941 atccgaactg catttgcaac agtcaattct ggatgcaagt ttattcgtag ggataaaaaa
    27001 gattagtgtt ggcttatgat gcaagctctt ttttatttta ggaattagag agggatttgt
    27061 ccttctatga ttttttgcta taatagggaa gatgtttatt ttatgaaaga atagttgagg
    27121 gaatttaaat gaataaaaaa ttgatgcaag gaacattttg gctaaccttt gctaatcttc
    27181 tatgtaaagt tttaggggta gtctatttga ttccctggct aagtatgatg gggaacaatc
    27241 aagatggtat gcttgctacg acattgtata atgttggcta tcttccttat ggattgttcc
    27301 tgatgcttgg tacagtcgga tttccaaatg cgattgcaaa aaaagtagct gtagccacaa
    27361 aagaaggaga taacgctgct tgtcggctga tttttagaag tacgatcaat atcatgtttg
    27421 tcatcggtat cgcctctgct gcactgatgt atttatttgc tcctttacta gccggaatca
    27481 gtccgattgc taacgttaat aatgggatac tagctatcag aagtttatgc ccatctttga
    27541 ttgctatccc aattcttagt gcaatgagag gatatttcca aggaaaaaat gatctgcggc
    27601 cttatggaac ttctttgatt atcgaacagg ctgtgcgagt gatcgttatc ttggctggta
    27661 cttattactt gcgcgtattg actgacggaa ccatattaga agctgtattg atcagtacag
    27721 tcgcttcttt cttcggtggg ttagctgcga ttatccatat gtatatcgtc ggacgcagaa
    27781 aagacttctt cgaacttaaa gattttttga tttccagccg ttatttcgaa agagaaaacc
    27841 gatctgcctc tgtctctatc attcgggaaa cactaccgtt tatttttgtc ggctcagtca
    27901 ttactatcgt tcaaatgatc gaccaagtaa cgatgaaacc actgcttcac tttttccgtc
    27961 cagagatcgc agatcagcaa ctggaattct tattcagccg tgcttctgtc aatccaaata
    28021 aattgacatt gatcctgatc tccatggtag gaacagtagc tataagcagc ttgccaatat
    28081 taagcacgat gaagaaaaaa gatcggatac aaatcgaaaa aacagtagga gatagttttt
    28141 cgattgcgtt attgattctt cttccttcat tgactggaat gtctttatta gctggaccac
    28201 tatacacatt gttttttggc tatgatcctg aaagtgtcgg atatttccaa atggctttgc
    28261 tagcttcttt gtttttctct ttattcacga tcctatctac gatgcttcaa tctttgaatc
    28321 accatcgttt tgcgatccga ttaactgtag aagcaattat cctgaaagtc atcttccaag
    28381 taatcggatt aggattagtt ggcggatacg ggatgagctt atcaaatggc ttagcattcg
    28441 gtattgtctt tgttcgcggc tatcacttta tgtgcaaaga ataccgaata gcacctttag
    28501 caaagatcag caattttttc ttaaaaactt tccgctccac cctgattatg cttgcagtat
    28561 gttttgccgt tttctttttg ctgaatcagc gattgtcaat ggaatcaaaa agctatgcaa
    28621 tgatttattg tgtggctgta ggaagtattg gcggcttagt atttttattt tctcaattcg
    28681 gaaaaaatgg gtttcgaatg ttgaaaaatg ttaaacatca tagcagaagc aaagaatagg
    28741 ttaactaatc gttttttgct gtcacttgaa aaacggcaac tcgtatgatt acgcttgtcg
    28801 tttttctatt ttccaatttt agtttcatat ctaatcttac ttatgatata gttataaggt
    28861 ctggaaaaat tctttgaaac gaggaaatta aacacatgaa acttgcagta gttacagata
    28921 gttcggcata tctgccggaa cgtatcaaga accatcccga cttattcgtt attccaatcc
    28981 ctttgattat ggatgggaaa atttataacg aaggaatcga tatcgaagcg gatgaatatt
    29041 atggactttt aaaaaacagt aaagattttc ctactacttc acaacctgtc gtaggggaag
    29101 ttttgggttt atatgaggaa ttgaaagaga aagggtatga cacgatttta agtatccatc
    29161 tttcttcagg gatttctggc tttgtcaaca cattatttgc gatgaaagat gacatcagcg
    29221 gagtaacggt cattccttat gactctaaga tcactagtat gccgatggga cacatggtag
    29281 aagctgcctt agacttaaat gatgaaggtc agtcccttga tgaaatactt gcacatatcg
    29341 atcgaatccg agataatacc tacgcttatc tgattgtaga tgatttgaac aatttagtac
    29401 gaggaggacg tttgacaaat ggtgcagcgc tgattggcag cttattaaaa atcaaaccga
    29461 tcctgacatt ttctgaaggg aaaattgttt tattcgaaaa aatccgttca agtaaaaaag
    29521 catttgctcg agctgaagaa attattggta gaagaaataa cgaaatacaa ccgccagtca
    29581 aactttacgt gatacatgca aataatttag aagtagcgat tgcggagaaa gagaaattgc
    29641 agaaaaaata tccaaatgca gaaatcgaaa ttggtcattt cggaccagtc attggtacac
    29701 atttaggtga aaaagccatc ggcattgcca tttcagcgca ataattcctt ttattcaaaa
    29761 aacataccaa aaatattcca acatcatctt ggactttcta catgttacta atgagcgtgt
    29821 aaaagaacga gatggtgttt ttatttctat caatgaagct ctttttcttt gcaatcctca
    29881 cttcaatcct ctataatgtc gcatatagtt tagtaaatga gtaaactact aatttactta
    29941 tttactaaaa ataaaaggat gaggagttaa aataatggaa ataccaacaa atttaaaaca
    30001 taaaccagta atcgttgtag aagactatga taaagttgat ggaagaaatg cattaaatac
    30061 ggatgcaaaa gggctttcac tgggccttgc tcagtggaat gatcgtggaa aagtcgatat
    30121 ctcaggcaag gtatggcgac atactggaga aaaatggtca cgacagtcgg aagaattacc
    30181 aatcacacgt attttagatt tagcgatctt agctgcacaa ggaagtttat acttccaaga
    30241 tgcttatcgt tatgaaaaat tttatgatcc agaaaatcca gtcgtagaca tcattggatt
    30301 acaagggaac cgaatgacgg tagaagtaga taccaaaaat ccaaagatcg atgaagacat
    30361 cattttgtat tacgatacac tacaaaaaga cggagaactg attggggaac gattccgtat
    30421 tttaaaacgt cttttagatg agctaggata ttaatagaca gagatgatca aaaggggaag
    30481 agaagcatgg agaatttctc actaacagaa aaccgaacct tttcacggct agaaaagcaa
    30541 atgatctgga agaaaccgaa aagccatcgg acaagtgcag aagaatggcg gatcgcctcc
    30601 gaaatcaaag ggaattggca agatcctgaa atgaaaatca gtaacgtact tttggaagga
    30661 gatgccgggt cggggaagac acaattagcc aaagcactat ctgctgatct gcaacttccc
    30721 tatacaaaag tgacctgttt tgcagatatg gacaaatcag atgttttcgg agccttatta
    30781 cctgtagtag attctaataa ggaacaagac caagaattac tagaagctat ttaccaaaca
    30841 gatacacttg aagctgtact gacactgatc cagaaccatt acggcattga tcctttttct
    30901 gctaaagaaa aattagcaga gctagttcaa aggatcgaag ctgattatcc agatgcaatc
    30961 cattacagct attacccttc tgaaatcgtt cgagcgattg aaaaaggata tttattagag
    31021 attcaagagc cgactgtcat ccgagatgcc tctgttcttg tggcacttaa ctcagcgctc
    31081 gaaccaaatg ggatgttgaa tttaccgaca ggaatcattc gtcgccatcc agattgcgtc
    31141 attgtgatca ctacaaatcg aaattaccaa ggaaatcgcc cattaaatga atctttaaga
    31201 gatcggatgc aacatgcgga aaaaatggat cttcctgcct tagaagtcat ggcagaacgt
    31261 gcgatggcga aaactatgat ccaaaaacaa gaacttctct taaagatggc agagattatc
    31321 cgtttgttgg atgaaactgc aaaagctaac gccatcaaag gtgtagcagg aatgcgttct
    31381 tatttttatt gggcaaatac ctataagcaa ggacaagatt tactccagtc gatttatcca
    31441 aaagttttgt ataaattatc cactgattca gatgaattgg caattcttga acaagctttg
    31501 tctgacagtg gattgctact ggaacttcag gacatattga gaaaagaaaa atggggtcat
    31561 cctcaatctg agcatacaaa aggaagaacc attagcgccg aagaagcaaa tgaacgaaac
    31621 atcactgaaa atgctgaaga aattctgcgc ttagatgaaa agaaatcgtt gtctgctgaa
    31681 gaaccaaatg agggagaaga gaaacaagaa gaaacaatag aaaaaaacga gattcctcct
    31741 caaatgcaaa aagaacgcag tagcgatatc gaaggaaaaa atcaaaaaga acaacaaaca
    31801 ggagatgatt ctcaagaaat gtctgcttct gacatggaag cacatgataa ggaaatcaag
    31861 aagcaactga ataaagaagc gcgacaaatc atgaaggaaa cgattcatga aaaagaaggt
    31921 ctcatcgttc accgaccagc tttccaagga aaaacgccgg aagcacgtga gctacacatg
    31981 caagtaatgc caatagtaga atcacttagc cggcaaattt tagagttact ggataatgaa
    32041 caaacagaga cgtaccaaaa aggaaaatac gaaggtcagc ggttcaatgc aagcaaagta
    32101 gcatatggtg atttgagaaa ttttgacaaa aagaacccgc cacatgagca accttcttta
    32161 gcggtagctg tacggatcga tgaatctggg tcaatgatac gggatgatcg gatcgaagcg
    32221 gcaaaaaaag cagcgattgc cattgccgaa ttttctaaga aagtcgatat cccattgttg
    32281 atttacggag atacagcaga ccgttcgtca agagaaaaga cttctttgtt ttcttataaa
    32341 gaatttgaag acggatttca atggttaaat gaaaaattag tcactatgaa accaaggcaa
    32401 aacaatcgtg atggtgctgc acttcgttta gcagcagaaa aattaaacag acaatccgca
    32461 acaaccaaac tgttgcttaa tattagtgac ggtcagccaa aagcgttgcc ggattataca
    32521 ggcaaaaaag caaaagaaga tatccagtct gttttgaaag aatatgaacg tcaaggaatc
    32581 ctatttgtct ccgcagctat tggccaagac aaagaagaaa tcaagtcgat ctacggtgaa
    32641 agtcgttttg tagatattac tgacttgaat gaatttccca agcaaatgat tcaactgatt
    32701 gcccgctatc tatgataaaa taaagctcaa cgaacgcact tagcagattc gttgagcttt
    32761 tcgtttctag ttaccggtaa caaggatact tctaaaatag aatcggttat aatcaagagg
    32821 gaccgttaaa ggagtgaaac gatatgatac aagaacaaaa atggtggaaa gaagcagtag
    32881 gctatcaaat ctatcctgct agtttcaaag atagcaatgg cgatggtcaa ggagacatca
    32941 atgggatccg tgaaaaactt aattatttga aagatcttgg tatcggcttt atctggatca
    33001 atccgatcta tcaatctcca tttgtcgata atggttatga cgtaagtgac tatcaagata
    33061 tagaagagag attcggaacg atggaagatt ttgatttatt gctaaaagaa gcacatgaat
    33121 tagggatcaa agtgattatg gatcttgtca tcaaccatag ttcggatcag catcaatggt
    33181 ttgaagaatc gaaaaaatct aaagaaagcc cgtatcgcga ttattacatt tgggtcgacg
    33241 gggtagatgg caaagaaccg aataattgga catcgatttt cggcggttct gcttgggagt
    33301 attctcatga aactggacag tattatctgc atgtttttgc aaaagaacaa ccagacttaa
    33361 attgggaaag cgagaaattg aaagaagaac tattcaatat gatccgatgg tggttggata
    33421 aagggataga tggatttcgt ttagatgcga tttctcatgt aaaaaaagat gaatattcag
    33481 taaaagccac agagaaccct ttctcaccct ttcaaaatgt ctcaggaatc gaagaacatt
    33541 tgaccgattt gaaacatgtt tttgaagagt acgatatcat gactgtcgga gaagcaagtg
    33601 gtgtcactgc agaagaagga ccacaatggg tagggaaaga cggttatttc gatatgatat
    33661 tcgaatttga tcatatccat atctggcagc aagaaaaaga agggcaatta gatgtcctta
    33721 aattgaaact tgcattaagc gcttggcaaa cttcattgga tggtatcgga tggaacgctt
    33781 tatatatgga aaaccatgat gttcctcgtg ccgtttcagt gtttggagat actcgtcccg
    33841 atttttgggc tatgtctgca aaagcaatcg ctatgatgta tttctttttg caaggtacgc
    33901 catttattta tcaaggacag gaaatcggaa tgacgaatat gccctttgaa tcgatcgatc
    33961 aagttgatgc agtagattcg aaaagacttt ataaaaggct gcttgcggaa ggtaagacaa
    34021 gagaagaagc attggatatc attcgtgaaa caacgagaga caacagcagg acacccatgc
    34081 aatggacttc ggaacaatat gctggttttt ctacacatga accttggctg atcactaatc
    34141 caaataccaa aacgatcaat gtagaacaac aagaatatga accagagtcg gtcctgcaat
    34201 tctataagaa catgatccgc attagacaaa ccaataaagg tctgatatac ggttcttata
    34261 aagaatatct tcatgaacat ccacaacttt atgtctatga aagatattta gaagatgaac
    34321 aatatcttat tatggtaaac ttaacagaat cacttgctga ctatgaactt ccaaaagaag
    34381 cagatcagtc ctggacatta ctcttgtcaa attcctctag cggagaattt gaagctaaag
    34441 gcatactagc accttatgaa gctcggttat ataaaacaaa caagtaaaac ttcctcgtta
    34501 aagttcatta gttggacttt gcgaggaagt ttttcagatt gctctgtcaa ttactcattt
    34561 caataattcg ctctaggacc accgatatat ttaggacgag agcgaagggc tgtcacgtga
    34621 gcttgtccaa gggttttcaa acgaggtctg acaggtactt ggacatgttt gatatgcata
    34681 ccgattgatg tgtcaccgat atcgataccg gcttgtccaa ctacgtgttc cacttcgaca
    34741 ggatcattga actggtcaaa agcagcaaca gaacaagcac ctccagcatg tagtgcagga
    34801 acaacagaga caatttcgaa attttttgct tctgccactg ttcgttctac tactaatgct
    34861 cggttcaaat gttcacaacc ttggacagct agcgcaattt ctttaggatc caacaactct
    34921 tttaacgtac ggatgatcca ttgaccaact tccgcactgg aattttttcc aatatgtcct
    34981 ccaacgactt cgcttgtgct gcatcctaaa acaaaaagat cacctttttt caagtgtgcc
    35041 tcagccaata tgtcattaac tatttcagtc aattggtctt ttaattcttt ttctgacaac
    35101 ttcattttct aaaaccttct ttttcaatta atattgcttc cgtgcttgaa tacgttgaag
    35161 acttgcagtt ataggaaagg caagtcccat tccaatcaga ttttggaaga tgtttcctgg
    35221 tatagaagcc actccagccg gccaatcata taaaatccaa ccggcgatac catagccgat
    35281 gatcataact aagcttccta ataaaagccc taatccccac atacgagtag aagatttgct
    35341 gaaagaacca gcaacatatc cttgtaaccc gtggatcact aatgaaaaaa ctgcccactg
    35401 cggatatcct gaaatcaaat cgatcaatag accactggaa gcaccaacaa ctaatccacc
    35461 cgttggacca taaagaaaag cagcggtata gatcccggcc tcgcataatg tcacaaatcc
    35521 attcgtagcc ggtacaggga tcaaaattgt taatgaaagg gcaactgtca acgcaatcag
    35581 catagcatag atcgttaatt gcttagtttt catttctcat tcctcctttt tgaataccgc
    35641 cagaccagac acttccggta tgatcgttca tcagcacgcc attagaaata caatgggcaa
    35701 caaatttttt actttctgct actgctttgg taaaatctgc ccctaacaca agattcgctg
    35761 ttattgcaga agaaaaggca caaccggccc cgtttactgt tgtagtgtcg atttttttat
    35821 gagaaaatac ctcataatga tcaattgaat agagaagatc cacagcttca tctccagcca
    35881 tccttgtgcc gcctttgatc acaatgtttt ttgttcctga agcagtgagt tctttagcga
    35941 gatggatcat ttctgttaac gaagagggaa gagcttgacc agaaagtaaa gcagcttctg
    36001 ccaaattagg cgtaatcatc gtaacaagtg gaaaaagttc ttcgatgagc tgcgaaatat
    36061 acaattgatt gatcacagct tcagtttctt tgaatgccaa aacagggtct aaaatgattg
    36121 ggatattttg ttttgttttt atgaagtctc gaacaaccat gattgcttca cttgaattca
    36181 ataacccaat tttgatacca tctaatgaag tcattttatc aatcgaaact aactgtcgtt
    36241 taagcaattc caaagatata gattccagca taaatcgctc attaatatct agtgccccta
    36301 tagaagtcaa ggcgcttagt ccgaatagac caaaattctc aaaagttttt aaatctgttt
    36361 ggattcctcc accagcaaat ggatcagaac cgccaattgt caagattctt ttcataacat
    36421 tttcctccat gaataagagt ataacgaaat tttcaaaaaa gaaaaacagc caattggcat
    36481 atttttatct catccaattt aaaaaaacaa aaagaaaaga aagaccaaaa tggatctttc
    36541 tttccttaaa tagttaggac ttttgtgatt ttaattcttt ctcgatttga agccgttgca
    36601 ctttcattgt agctgttcgc gggattgcat caaaatcacg gatgataggg acgttcaagc
    36661 gaggaagttc atggacttgc tcccaccatc gattccaatc catttcttta tcaggagcta
    36721 aagcaataat cggttgtgga gaatgatttt tatcccttac aatcactact tctgccaaaa
    36781 aatctaacga atctaataaa aagtcttcaa tagctaatgt actattgatc gtttcgatca
    36841 aatccacttg ccgatctttc aaaaataggt ggccatgctt atccataaaa ccgtaatctc
    36901 cgctatccca ccaatcgcca taaacatttt cctggaaccg tgcatcttcc ttgtaataag
    36961 tcaaagcccg tcctttagac agtaattgta tatgaccatc tgtgttttca ggtaggacat
    37021 tcccaactga atctgtaatc cgagcgcttg tcatgtcttc cagtccaacg cccatatctc
    37081 ttgcatcact tgttttcaaa ctctctagtg tatgagcctt aagaatcatt ggtccgcatt
    37141 cactttggcc atatacttga agaaataccg catcctgtgc catcgacgtt cgcaaaaatg
    37201 tcttcattgt ctggttgttt atagcatcaa aagtggagtg atagtatcgg atacccgaaa
    37261 aagcttctgg atgctcctta gcagtaaaac gccactgaac aaagttattc ggatgggtct
    37321 ctagtgcaat tggccggtga gcttccaaca tatgaacaac ttttgaactt tgtgcgtttg
    37381 ctaaaggcat cataggaaat cccatggaca tcaaagaaga gataccaata ttgaatctgg
    37441 aatgcactgg agagatgtga aaagcgatta atttcttttc cgaaattttt gtgaaaactg
    37501 ttttttgcca tttcgtccgc catcccatag aatgagcaga atgacaaata agtttaggga
    37561 taccagttgt accagaagta tgggtcatat aagaaatttc atttttgtct aaaaatgatt
    37621 gagaaacaga caaagcaggt tgttccatta aataaagaat aggaa
//
LOCUS       DACGMI010000027        37454 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.028, whole genome shotgun sequence.
ACCESSION   DACGMI010000027 DACGMI010000000
VERSION     DACGMI010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.028"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            23..646
                     /locus_tag="IXT46_001472"
     CDS             23..646
                     /locus_tag="IXT46_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947393.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="IXT46_001473"
     CDS             1096..2145
                     /locus_tag="IXT46_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4947394.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="IXT46_001474"
     CDS             2142..3023
                     /locus_tag="IXT46_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4947395.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="IXT46_001475"
     CDS             3026..3796
                     /locus_tag="IXT46_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4947396.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="IXT46_001476"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="IXT46_001476"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAQ4947397.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="IXT46_001477"
     CDS             5107..6270
                     /locus_tag="IXT46_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAQ4947398.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="IXT46_001478"
     CDS             6387..6797
                     /locus_tag="IXT46_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAQ4947399.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="IXT46_001479"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="IXT46_001479"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAQ4947400.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9337..9654
                     /locus_tag="IXT46_001480"
     CDS             9337..9654
                     /locus_tag="IXT46_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947401.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            9814..10050
                     /locus_tag="IXT46_001481"
     CDS             9814..10050
                     /locus_tag="IXT46_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4947402.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="IXT46_001482"
     CDS             10047..10445
                     /locus_tag="IXT46_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAQ4947403.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11112..12056)
                     /locus_tag="IXT46_001483"
     CDS             complement(11112..12056)
                     /locus_tag="IXT46_001483"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAQ4947404.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12352..13296)
                     /locus_tag="IXT46_001484"
     CDS             complement(12352..13296)
                     /locus_tag="IXT46_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4947405.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13517..14731
                     /locus_tag="IXT46_001485"
     CDS             13517..14731
                     /locus_tag="IXT46_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4947406.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14753..16768
                     /locus_tag="IXT46_001486"
     CDS             14753..16768
                     /locus_tag="IXT46_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HAQ4947407.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16851..18224)
                     /locus_tag="IXT46_001487"
     CDS             complement(16851..18224)
                     /locus_tag="IXT46_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAQ4947408.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18250..18534)
                     /locus_tag="IXT46_001488"
     CDS             complement(18250..18534)
                     /locus_tag="IXT46_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4947409.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18536..20551)
                     /locus_tag="IXT46_001489"
     CDS             complement(18536..20551)
                     /locus_tag="IXT46_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4947410.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20730..21035)
                     /locus_tag="IXT46_001490"
     CDS             complement(20730..21035)
                     /locus_tag="IXT46_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAQ4947411.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21124..22155)
                     /locus_tag="IXT46_001491"
     CDS             complement(21124..22155)
                     /locus_tag="IXT46_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAQ4947412.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22362..23237
                     /locus_tag="IXT46_001492"
     CDS             22362..23237
                     /locus_tag="IXT46_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4947413.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23389..24231)
                     /locus_tag="IXT46_001493"
     CDS             complement(23389..24231)
                     /locus_tag="IXT46_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4947414.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24323..26200)
                     /locus_tag="IXT46_001494"
     CDS             complement(24323..26200)
                     /locus_tag="IXT46_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4947415.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26197..27618)
                     /locus_tag="IXT46_001495"
     CDS             complement(26197..27618)
                     /locus_tag="IXT46_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4947416.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27621..31010)
                     /locus_tag="IXT46_001496"
                     /pseudo
     CDS             complement(27621..31010)
                     /locus_tag="IXT46_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
     gene            31267..32658
                     /locus_tag="IXT46_001497"
     CDS             31267..32658
                     /locus_tag="IXT46_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4947417.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32731..33378)
                     /locus_tag="IXT46_001498"
     CDS             complement(32731..33378)
                     /locus_tag="IXT46_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4947418.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33386..34072)
                     /locus_tag="IXT46_001499"
     CDS             complement(33386..34072)
                     /locus_tag="IXT46_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947419.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34078..35151)
                     /locus_tag="IXT46_001500"
     CDS             complement(34078..35151)
                     /locus_tag="IXT46_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAQ4947420.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35373..36047
                     /locus_tag="IXT46_001501"
     CDS             35373..36047
                     /locus_tag="IXT46_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4947421.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36052..37392
                     /locus_tag="IXT46_001502"
     CDS             36052..37392
                     /locus_tag="IXT46_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4947422.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
BASE COUNT        11613 a         6787 c         7127 g        11927 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag
    10681 tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc
    10741 catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg
    10801 tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt
    10861 agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca
    10921 ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga
    10981 tacattttcg gaccgattaa ttttaaccat tctgtttatt tgcttaccta ttagatatca
    11041 ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata
    11101 ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg
    11161 aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg
    11221 tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa
    11281 gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta
    11341 ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta
    11401 cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca
    11461 atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca
    11521 ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg
    11581 atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt
    11641 ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca
    11701 acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac
    11761 gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg
    11821 ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt
    11881 tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga
    11941 ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata
    12001 cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat
    12061 aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca
    12121 ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa acgaattcct
    12181 gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca
    12241 aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca
    12301 atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt
    12361 atttctccat tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt
    12421 cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat
    12481 cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa
    12541 atacattttc aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc
    12601 ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt
    12661 ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat
    12721 cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata
    12781 aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg
    12841 aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag
    12901 attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa
    12961 gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc
    13021 aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca
    13081 tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc
    13141 atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat
    13201 ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc
    13261 acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat tcagctagtt
    13321 ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca cgctgtactg
    13381 ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg gacatgaact
    13441 tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga taagcgctta
    13501 caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc tgctgtcagt
    13561 ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta tgtcagctac
    13621 ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct cttttatggt
    13681 cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa aacaaactgt
    13741 gatcatcgga ttagtgattg catcgatttg tggtatcctc cccctcttct cacaaagtta
    13801 cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga tcaattcttt
    13861 ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta tgattggttt
    13921 tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag gacagctagt
    13981 acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta ttcttgtctt
    14041 gtttgttttg tttgttccta cacctgaaac aactgaactt caatcgcatg gcacagcccc
    14101 aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt ttctcttgct
    14161 ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga cgacttattc
    14221 tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg caagtatggc
    14281 tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc ttacactttc
    14341 tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc tgtatgtgat
    14401 tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt acttattcaa
    14461 ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa tcttattggt
    14521 tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct cttttgcttc
    14581 tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt tgattagcgc
    14641 gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa gagtagatga
    14701 agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta aaatgacaaa
    14761 tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc gccatggact
    14821 gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact ggtacatgga
    14881 tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac cttccatgtt
    14941 taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac atccatgtgg
    15001 aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag gacatacatc
    15061 agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg gctggacagc
    15121 aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg atatcgcaaa
    15181 agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg aaacggagat
    15241 tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag aactaatatc
    15301 tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg tagaagctat
    15361 ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga aagctcgtaa
    15421 acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc aacttcaagt
    15481 ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt cttctttact
    15541 gaatcagatc tggtcagtat cagaagaagc cttcaagtta tgtagtgatt tgttttttat
    15601 cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat cattcatgat
    15661 caatcaatat cttttttttg acgaggaaat caataaacga acgatattag cattaagagg
    15721 acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct tgtggttgat
    15781 tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca tcgtctaccc
    15841 taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag ggtttattta
    15901 tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag aaggaacgct
    15961 tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt gcggagatat
    16021 cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc aagaaaaata
    16081 tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg gcgcttttat
    16141 cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt tcgctgtttt
    16201 attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct tattgaatga
    16261 cactatcaca cagattacta ctccatattt caaattctat gaacaagatg ctttatgcaa
    16321 actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag ggatgttatc
    16381 tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa atgaaaagta
    16441 cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag caagcccaat
    16501 ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt atgaagaatt
    16561 tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac ctatcaaaga
    16621 tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg atagaacagg
    16681 cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc cacttgtctt
    16741 aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat atcagaagac
    16801 tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc ttaattctgt
    16861 tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa tacgacaagt
    16921 aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc tagtttccca
    16981 agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc gattttaaga
    17041 tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct attgaaagca
    17101 gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc agaagcagct
    17161 ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa gcctatcata
    17221 gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa tacagcatta
    17281 ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg tacgagtttt
    17341 ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac cccttgaagg
    17401 acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat tacagcgttg
    17461 tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc aagtgcgaca
    17521 tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa gctgaaactt
    17581 ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt tccgatccat
    17641 ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt gtttccagtg
    17701 atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt tccttcgaag
    17761 accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac taaaatgact
    17821 gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa tttatatctt
    17881 gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa agcagtaggt
    17941 gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac tactccttga
    18001 gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact gattaaacca
    18061 gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg gatcacttct
    18121 gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac gaggatggag
    18181 ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag ttcctccctt
    18241 gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt cttcgctgtc
    18301 aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg tatctttcaa
    18361 agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa catccgtatg
    18421 acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt tgatgttcat
    18481 ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt tcatatcatt
    18541 cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt aataaatctt
    18601 gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga agatgtgcct
    18661 cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga ttatcaagca
    18721 gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg ccatcttctg
    18781 gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca tactgctcca
    18841 cgcgctcgat catagctttg atataacttt cttctatttt attttctgat aatagcggct
    18901 gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat tggatcattt
    18961 cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct aaaagtttgt
    19021 tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct tttaattcga
    19081 tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat cctggtatca
    19141 gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc atgattggat
    19201 gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta gaaaaaataa
    19261 tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc tctgtaaaaa
    19321 agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag ctaatgccac
    19381 ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc gcttttctga
    19441 tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg ctcttcccta
    19501 ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa gcatattgat
    19561 gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata cgaaaatagg
    19621 cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca aattctacgg
    19681 ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa aaatcaagtg
    19741 caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa aatataatct
    19801 ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta atgtcagtga
    19861 ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt tttccaattc
    19921 gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt gcgaatcgaa
    19981 gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa taatcaatgg
    20041 aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc atcaaacgag
    20101 cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc ctaaaaccag
    20161 ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt atctttttga
    20221 tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga aaaacagaaa
    20281 cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct tgttcggtat
    20341 acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt gctcggaatt
    20401 tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat tgtttgatcg
    20461 cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt tctcttggtg
    20521 ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac ttatattcta
    20581 gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg atttttttta
    20641 cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg accaaatgtc
    20701 tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt ttttgaggtc
    20761 agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt ttcaaagtga
    20821 ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa agctgtttct
    20881 ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc ttctgtttca
    20941 ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat tgaacctctt
    21001 aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag tagttctata
    21061 ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat tcttacaaat
    21121 atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca aaattttcat
    21181 ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta atgtctcgta
    21241 aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt cttcatgata
    21301 actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat cgataccaaa
    21361 gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat cttttgtttg
    21421 tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt tgatgcggaa
    21481 ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat cgaagtaatc
    21541 attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat ctggttcgcc
    21601 gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat agctgttcgc
    21661 agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat aatgcatttc
    21721 tacttctaaa atatccccta attttccgct ttcgattact ttttggactg tcaagaagtc
    21781 agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt ttgctaatgc
    21841 aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta gtacattctt
    21901 accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg tagtgatgac
    21961 aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat attcgatgtc
    22021 ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat tgattttgtt
    22081 cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat tgccaagata
    22141 agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata tcctagaaaa
    22201 gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac acttgttatc
    22261 attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga tagtagcgga
    22321 accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt gaagaaaaac
    22381 taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac atccgtagga
    22441 atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg tatacttccc
    22501 attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa gaattccgtt
    22561 tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg attgatccta
    22621 attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg gcggatttat
    22681 cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta gatcaaatcg
    22741 gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat tctcaaatca
    22801 cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc atggctgaag
    22861 aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc gccattttta
    22921 ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg aagcatgtag
    22981 aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa caggctgata
    23041 tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact ttctcctctc
    23101 aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct caaaattttg
    23161 aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc cttcttaaag
    23221 aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag tgtttgatag
    23281 gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac ctcagcctgt
    23341 ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct aacttctgtt
    23401 tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca gtatacatgc
    23461 agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta cttctttttg
    23521 aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat gactgttgac
    23581 catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga ttctcagatc
    23641 ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga gtgtccgtcc
    23701 attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg tgaacaactt
    23761 tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc cccccgtagg
    23821 ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat tcgtttcatc
    23881 aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg tatgtttctc
    23941 aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat ctgcacctgg
    24001 atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt ggattttagc
    24061 catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga tctgctgatc
    24121 cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta ttcctgagag
    24181 aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca tttgtgttct
    24241 ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc cgctgctcct
    24301 ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca aagtacagtc
    24361 cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc ttaccgcctg
    24421 ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc aactgtcctg
    24481 ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat ggaacatatt
    24541 tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct gtcacatcga
    24601 ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat acccagctga
    24661 cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct tgatcacgaa
    24721 cgacgaattc tgctccagca agtgtttggt ctgatgtaac gtcaccatct actttaacaa
    24781 atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt gtatgcccgt
    24841 tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg ttcaaatgca
    24901 tatagtaaac gaatttcaat gtaccgccag gagttaatga aggaatataa ttcggatcaa
    24961 ctgaaaccgt gaatccgtct gtttgctcag tgacagaata atttactggg tcgatttctt
    25021 tatttccatc atataaggca taagcatacg ttcctgaaga atcattatca aatgttaaag
    25081 cagcgtcatg agtatcgata agtttgaatg ttgtgtactt gttttgcgtt ccttctttat
    25141 cagcgatacc taatgggata ttgacagaaa tctcatattg aattttttca ccgattgcga
    25201 catcttttcc attcaattga ggtgttgttt tatcaacttt agacgtatca tttttgatgg
    25261 tcttttctac tggtgtttgg ctatttgcca ggatctcaaa aggcgtgatt gtttgctttt
    25321 caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt ccaacttcta
    25381 aatgattaac gatcaactgg cctttttcaa tagatgcctc ggcaaagtca ttgttgccga
    25441 tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatcagtt gtccaagtgt
    25501 acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtgttcct tcttctttag
    25561 aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt tttgtaactt
    25621 tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta tctagttctt
    25681 ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca gggaaagcta
    25741 aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc gtgtagactg
    25801 catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca gcatctgtcg
    25861 ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt gctgcatcca
    25921 cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa actgaaaatg
    25981 aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg ctgttttgga
    26041 ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga gctgctgtct
    26101 cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa ataaggaaaa
    26161 ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc ctgttctttt
    26221 tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc ctaaaagtgt
    26281 atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt tattgactac
    26341 tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg taaacggaat
    26401 ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc gataacttcc
    26461 tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt gaagcgcatc
    26521 tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat ttcctgcttt
    26581 gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg tctcgatttt
    26641 gacaaattgc ttactccctg tatatacaga gactttcttt gtactgacac caaaaccaaa
    26701 atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc ttagctgcat
    26761 ctgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga tcgaaaataa
    26821 aacatcaaat ccgtgaggtt tcttgtgtat gacaaagcct tctgtcagct tttctccatt
    26881 cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac tatctgacaa
    26941 ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg aataagtgat
    27001 tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa aaggtggatc
    27061 agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt tttgattgtt
    27121 ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga cgacttctgg
    27181 tactttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt tagcggccag
    27241 agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt ctgcggtaaa
    27301 cataccggaa gacgcaccgt tttttgcgat ctctgcttgt gcttcttcta ccgttttgcc
    27361 cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg tgacaccatt
    27421 taatcctcga tacgtttgta ataaagcttt ttcttgtccg tcatttggat gatttttcgg
    27481 cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt ctgtttctgt
    27541 ttctgttgct acctgagtaa aagctggttt aaatagtaac aagaagagac acatactaag
    27601 ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa aagataccaa
    27661 atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc aattcctccc
    27721 gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg gttgtttttg
    27781 gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga cccatcttcg
    27841 tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt aaaagtttcg
    27901 gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt ttcttgtcca
    27961 tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc tccttttaat
    28021 gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag tcgattttga
    28081 tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta aatgattttt
    28141 ccatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc ggcaggacca
    28201 gctgtttcaa cgactcgata tttaccaggt gtgagtgaat caaaactggc aagacctttt
    28261 tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt tttctgtagg
    28321 gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc atacttacgt
    28381 actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt atcatcggaa
    28441 gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt gatttcccaa
    28501 gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag cgtataggtc
    28561 atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc atgatctgtt
    28621 agtaaagtat caatagaatc tcctgttaat ttgaaaacag cgccaataag atccttttca
    28681 cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt agtatttttc
    28741 catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc tttgattgtt
    28801 tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat ctcttgataa
    28861 ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacgt atttgttgta
    28921 tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc atttgtcgta
    28981 tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt gttgtcaaat
    29041 tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga tggtataccg
    29101 aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc gttcatttga
    29161 taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg gtaatggatt
    29221 tggatttctt ggtcttttca taaatagatc tgattgctct tgatggtatt tccttctatg
    29281 gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga aagtgtacca
    29341 ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct tacagttgct
    29401 gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg atcagctgat
    29461 tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg agactctact
    29521 tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag accatgtatt
    29581 tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa cgtactgtcg
    29641 attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat tagagaagta
    29701 tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct gcttgattgt
    29761 gcgtgtaccc gctgtacttt ataggaaaat gttggtacac catccgtcag caaaacgatc
    29821 acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag tgctttttgt
    29881 gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt tttcactgaa
    29941 tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct tgagtagccg
    30001 acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc gacaaaacga
    30061 tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc tgaccagtct
    30121 acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg agcattcaaa
    30181 taaacatcaa acaatccggg tgtacttgtt tcctttgcat actttcgtat cgcatagtct
    30241 gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt aggatctcca
    30301 ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg atgatcaaga
    30361 acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg atcatctgtt
    30421 gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa ggataatgta
    30481 ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc ttctatttcg
    30541 tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc aataatgtca
    30601 tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc tggatcgatt
    30661 ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt aattttcccg
    30721 ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact taagtaattt
    30781 tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc atttagcttg
    30841 atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat tgtttctaaa
    30901 actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt tgataaactc
    30961 aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat ttttcccctc
    31021 ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa acaggcgtta
    31081 cataatttta tttattttaa tatgataatt attatacgaa gggcgctaaa gggaatcaca
    31141 ccaattttca taccaattgg tttcatttat gaagttgatt ccttcgatta atgagcgttt
    31201 cattgaaaga aaagggttga gggagaaaaa catatgatca ggttgttgga atgaaactat
    31261 agaaagatgg aaaaaatcat tcgaattctg tccatttctg acaagtggat gactaaaaaa
    31321 gaacttgcca aacgaattgg tagttcagaa tctacatttg taaggtatat cgaagagatc
    31381 aaaatccgct ggggaacgga tgtaacgatt caatcttcac aaaaattggg gtatcgtctt
    31441 gaacatttga atgtaccagc ttatttaaat gttctgatgg aaatgtcgca aagttctaca
    31501 aacagtcgtt tattaaatga gattattgtc aatccgggta aaacgattga gtattattgt
    31561 gaaaaaattt ccatcagccg gtcttctttt acacgtaagt tgaaacaatg caatcaaatt
    31621 ttagaaagct atttattaaa agtgatcgtt gaccaaggtt ttcagttaac tagccttaaa
    31681 agtgagctcc agttgcgtat ctttgttacc tttttctttt taagttacta cggaagacgc
    31741 acgttgccat ttccaatcga aaaaaagaag atcaaagaaa ttatggtcaa gaataattgt
    31801 cagatgaatt tgtttcagga agaaagccca tatgagcaat ctttctttat tatgtatttt
    31861 gttgtgcatc tcatgagaga atcccaagga actccatttg aatggaaagc tggagactct
    31921 tatgtacagt tgataaatat cgataaaaaa gacttcttaa tcttgaaaaa tctcttagga
    31981 aaattgaagt acagcagcta tataaaagta gtgaactatt ttgtcaatac gattttttca
    32041 gaattttcgg agaaagaaaa aaatgaaatc agtgagcaga tacgaaaaaa tatgtcctac
    32101 tgttcgtttt catccgctga ttgcaaagaa aaaaacgaag aatatgttgt tcaattatta
    32161 acgcaaattt attttttctc ccgtattttc ccatacgata cgactcattt gacgatccgt
    32221 gcaacttact ttgcacagca gatgcaacac cgccagatac gtctatatgc tggatttcgt
    32281 gcagaacttc aattttattc cactctactg aatcagaatc tgatttatta tttatctagc
    32341 tatatctttt ggatgcttat cggtaatcct gaaattcacc attatacttc tgataaaaaa
    32401 atactgatta tcagcgactt aagtcttcga catagtcaat atattgaaga atatatcagt
    32461 gatattcttg ctgtgcataa aattcactct gagacaactg ctattactga agatcagctg
    32521 tcgaaataca atcttctcga gtatgatctg atcgttacga atcaacccat tttgaatgcc
    32581 catgttcctc atatattgat tgatgatagt gtgtcattcg caaatgaaga agaactcatc
    32641 cgcttattcg agttatgaat aatcaaaaaa cagctatgta taaaccaccc tgataaaaat
    32701 ttcaggacaa atacacatag ctgtttcttt ttattgtatt ccttcagcaa tccaacgaga
    32761 tttatagcga aagtctttta acaactcttc ttttgtccaa ttatttgcaa tgagatccgt
    32821 caaagtgttc attacgaggg tcatggaaaa gtataggaaa ctaactgctt cttccgacga
    32881 ttgaatggag aaatgattga ttcttaataa ttccagccat ttttcgttca ttggagaatc
    32941 agccgatagt tctctacgtt tggttgtctg ctgatcattt cgctgggtta acaagtataa
    33001 cctttgccaa tagatacttt cgtgatctaa gtcgcagcac cactctaaat atttttcgat
    33061 ccccaaaaag aaatgttgtt tgttttcgct aatgaatttt aagatatctt gatggactat
    33121 gtgagaactg cttttgatcg tatacaaata agcatcttcc aaatcttgaa aatatttata
    33181 aaaagcaccg cgcgacatcc ccatcttgtc aacgatttct gagactttga cttggctgat
    33241 gtgctgtgag caaaatatct ccagtaatag gtcatcgatt ctctgtttct ttgcgttcga
    33301 taaattgaaa aaagtttctt ttggcatcca catctctcct ttatctctga ttatacgtgg
    33361 atagcccttc attgtcatga aggattcatt ccttcttttt ctcttcttct gtcaagtacc
    33421 catcttccat tcgataaacg cgatcactcc attgaatcat acggacatca tgagtaacca
    33481 taatagtcgc tttttgtttc tcatgagctt ctttaactag taatttgacg acttcatatg
    33541 catgatctgt atccaaacta gctgttggtt cgtctgctaa gatcaagctt ggctcattat
    33601 ataaagcgcg agcaattgcc actctctgtc tttctccacc agaaaggtct ttaggataac
    33661 tatttttaag tgactggata tctaaagatt gcagcaagga atcgattttt gttgaatctt
    33721 ctttttttga agtaacttgg tcaactagtt caaattgttc ctttaccgtt aaaaaaggaa
    33781 tcaaattaga gctttggaga ataaatccta tttctttaaa gcgtaaatct gctcgttttt
    33841 tttctggaag ctcagttagt gagtgaccgt tgatcactat ttctccggaa gtcggtgttt
    33901 gcaatcctcc tgaaatggta aggaaagtac ttttacctga accagaagga ccaatgatgc
    33961 tgacgaattc tccttccttt acataaaaat caattgcttt caaagctgag acctttgtat
    34021 gaccagaacc aaatgttttg gtaacttttt tcatcgttaa tatttttttc atttttatta
    34081 acctcctatt gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa acaatccgcc
    34141 tagcattgcg acaatgatca aaatcccact atatagcaac cattgtgacc aaaaaacagc
    34201 aaaaggcatc gcgcttggta aaatcagact agtcaaataa gcaaacaaaa gagcaagcag
    34261 aacgcctacc accccaacaa taaaggactg tgctactaaa gatttagcga tgaagaaatt
    34321 tttgatccct tgtgctttca ttactccaaa aatagcagtc ttctgaagtg tcatcacgta
    34381 catgaaaata ccgaccacgg cagcaaccac taagaacaaa aagtatatca tcgcatttaa
    34441 ggtcatattt tgggcagaat agccaggaat actttcaatg aatgtcccaa tagttaataa
    34501 ctgtagaccc ttcgatgctt tttctttcga aattttagct gaatccttta ttacgatccc
    34561 attgatcggc tgttcttctt cagaagcaaa cggctgttgt ccatacttca aagcagtcca
    34621 cgtatctagg gacgcataga tgacgggaga aactgtgtaa taagtttcag gaaagatacc
    34681 gacaatcgtc aaaggatcgt cgtaactgcc aattttgatc gtatctccaa ttttatagcc
    34741 tgaatcagcc agattttgag agatgatgat ttcattcttt gttttaaatt catgcccttt
    34801 cgtgagtttt ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa cattttcttt
    34861 gttttttcct ttgattgctc cgctgtacaa tccgattggt gctttctctc ctccttcaat
    34921 gtatttcaga tctcctcttg ttaattgtga agctgcaaat acttgatttg catcctccga
    34981 caaaacaatc tcttgtgcgt cccaatcatc gattgctttt ttaaactctt ctgaaagtcc
    35041 attcgctagt cctgacaaca tgaatacgac atacgcaatc aagaacataa taccgacgat
    35101 caagccatat cgtaatttag aatagcgaat ttctttgata gctagaaaca tttgtttttc
    35161 ctccctatga tagattgata gtgacaaaat gtcacttgtt gaatagtgta actctaaagt
    35221 gacaatttgt cacttgtgtt gtttttttct tatcaataaa ttgtctaaga catctttcga
    35281 taaaacctta acatgagtca taaaaaattt atttaagcct tatttatgct ttccatgata
    35341 aactaaagtg accaaatcaa tgaggtggga aaatgattaa actattagta gtagaagacg
    35401 ataaagtatt atccaataat ataaaagaaa tactcgctgc aatcggcgag ataacacaag
    35461 tttatgatgg tagtgaagga ctgttcgagt tggaaagtgg agtttatgat cttgcaatct
    35521 tggatttgat gatgccggaa atgaatggat atgaagtgtt agcaaaaata cggaaagaaa
    35581 aaatacagac tccagtattg attttgactg caaaagatag tttggaagat aagattgaag
    35641 gatttgaacg aggtgcagat gattatctaa caaaaccttt ctatcgagaa gaactgatca
    35701 tgcgcgtgaa agcattattg aaacgctcgc taggtctctt tgatgaaaat gttctgaagt
    35761 ataaggatat cagttgtgat ttaaaaagca atgaagtctt gtataaagaa caagttttgc
    35821 ccatacaagg aaaagagttt gaattgctcg tttatttttt acaaaataag ggaatcattt
    35881 tgacaaaaga gcagatattt gaccggatct ggggatttga ttctgatacg acgattacag
    35941 ttattgaagt ttatatgagc aacttacgaa aacatctgcg aagtactgga ttggataaag
    36001 aaatcaaaac cttacgtaat gtcggttata tactgcaaag ggtgtgatgc aatgaatgga
    36061 gatattacac gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc atttgctttt
    36121 atcttttttc ttttgggatt cattacttta cagatattaa accaatctgc atacagagaa
    36181 acagatctgt cattagagaa aataaatttt gattctcgaa cagtacaatt agagatacaa
    36241 agatatcagc aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa cagaacaaac
    36301 atggaacagc cattaatgga accatcaaat gaccgtttta acactcaagt gatcttgtgg
    36361 tctaaaaatg gtgagatatt gaataaagca gctattggtg ggcgtttcaa ccaaatcaaa
    36421 gaattaaaaa tggatacgaa aaatctgaat accatccaaa atattgaatt aaatgaagac
    36481 agtggctcat ctgccctctc tttccgttcg attacgaaaa aagcggagac gaatcaagat
    36541 ggcgttgcct acatccaaat tttagaaaat acaaatcaaa tcaagaattc attagcgact
    36601 tttcgcacga ttatgatttt gtgtatgatt gttttttgga ttctctctat tggtatcagt
    36661 tattacttgt ctagtctaag catgcgccct attattcttt cttggagaag acaaaaagaa
    36721 tttgttgaga atgcttctca tgaattgcgc acaccgttaa cgattattca aaatagtttg
    36781 gaacatcttt ttaccaagcc taatcatact attattgaag aatccgaaag catcgctcaa
    36841 gcattgtcag agacgaggcg cctcactgga ttgacttcgg atttgctgac aatcgctcgg
    36901 aatgattctg atcagcagct gctttcaaag caaatgatca atacacaaga atatatcgaa
    36961 caacttgtta aaccatttca agagatggcc atcatagatg gaaaagagtt tattctccat
    37021 aacgatgcaa cattagaagt accaattgat gaaaaaaaaa tccatcaagt tttggttatt
    37081 ttgctggata atgcattaaa atatacgaat ccagaagata agatcatttt ggattcatct
    37141 gttaaccata aagaatggct gattcacgta aagaatactg gcccttctat cagtgaagaa
    37201 gatcaagcaa ggatttttga tcgattttat cgggaagatc aatctcgggc gaaagagact
    37261 ggcggatacg ggcttggctt ggcaattgca aaacaggtaa tcgaacagca tcatggacag
    37321 atttctgtat ccaattatct tccacaagga gtcgatttta aagtccaatt gccgttgaag
    37381 cctaaaaaat aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt cacagccctt
    37441 ttttgttgcg aata
//
LOCUS       DACGMI010000028        35882 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.029, whole genome shotgun sequence.
ACCESSION   DACGMI010000028 DACGMI010000000
VERSION     DACGMI010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.029"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..1152
                     /locus_tag="IXT46_001503"
     CDS             <1..1152
                     /locus_tag="IXT46_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005236379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947423.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="IXT46_001504"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="IXT46_001504"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAQ4947424.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="IXT46_001505"
     CDS             2728..3003
                     /locus_tag="IXT46_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAQ4947425.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="IXT46_001506"
     CDS             3009..3776
                     /locus_tag="IXT46_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAQ4947426.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="IXT46_001507"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="IXT46_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAQ4947427.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="IXT46_001508"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="IXT46_001508"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAQ4947428.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLRKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="IXT46_001509"
     CDS             7920..8222
                     /locus_tag="IXT46_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAQ4947429.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="IXT46_001510"
     CDS             8225..9388
                     /locus_tag="IXT46_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAQ4947430.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="IXT46_001511"
     CDS             9414..12842
                     /locus_tag="IXT46_001511"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAQ4947431.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="IXT46_001512"
     CDS             12863..13987
                     /locus_tag="IXT46_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947432.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13977..14414
                     /locus_tag="IXT46_001513"
     CDS             13977..14414
                     /locus_tag="IXT46_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAQ4947433.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="IXT46_001514"
     CDS             14398..14736
                     /locus_tag="IXT46_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAQ4947434.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="IXT46_001515"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="IXT46_001515"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAQ4947435.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="IXT46_001516"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="IXT46_001516"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAQ4947436.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="IXT46_001517"
     CDS             15893..16936
                     /locus_tag="IXT46_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAQ4947437.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="IXT46_001518"
     CDS             17095..17823
                     /locus_tag="IXT46_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAQ4947438.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="IXT46_001519"
     CDS             17939..18184
                     /locus_tag="IXT46_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4947439.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="IXT46_001520"
     CDS             18181..18399
                     /locus_tag="IXT46_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAQ4947440.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="IXT46_001521"
     CDS             18535..19074
                     /locus_tag="IXT46_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAQ4947441.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="IXT46_001522"
     CDS             19067..21340
                     /locus_tag="IXT46_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAQ4947442.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="IXT46_001523"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="IXT46_001523"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAQ4947443.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /locus_tag="IXT46_001524"
     CDS             complement(22513..22767)
                     /locus_tag="IXT46_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAQ4947444.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="IXT46_001525"
     CDS             complement(23167..23436)
                     /locus_tag="IXT46_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947445.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23906..24361)
                     /locus_tag="IXT46_001526"
     CDS             complement(23906..24361)
                     /locus_tag="IXT46_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAQ4947446.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="IXT46_001527"
     CDS             complement(24499..26427)
                     /locus_tag="IXT46_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAQ4947447.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKVKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26624..27457)
                     /locus_tag="IXT46_001528"
     CDS             complement(26624..27457)
                     /locus_tag="IXT46_001528"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAQ4947448.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27649..28353)
                     /locus_tag="IXT46_001529"
     CDS             complement(27649..28353)
                     /locus_tag="IXT46_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4947449.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28376..29002)
                     /locus_tag="IXT46_001530"
     CDS             complement(28376..29002)
                     /locus_tag="IXT46_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4947450.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29328..31703
                     /locus_tag="IXT46_001531"
     CDS             29328..31703
                     /locus_tag="IXT46_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAQ4947451.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(31727..32218)
                     /locus_tag="IXT46_001532"
     CDS             complement(31727..32218)
                     /locus_tag="IXT46_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAQ4947452.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32405..33325
                     /locus_tag="IXT46_001533"
     CDS             32405..33325
                     /locus_tag="IXT46_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4947453.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33479..33823
                     /locus_tag="IXT46_001534"
     CDS             33479..33823
                     /locus_tag="IXT46_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAQ4947454.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34013..34513)
                     /locus_tag="IXT46_001535"
     CDS             complement(34013..34513)
                     /locus_tag="IXT46_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4947455.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35041..35124
                     /locus_tag="IXT46_001536"
     tRNA            35041..35124
                     /locus_tag="IXT46_001536"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35075..35077,aa:Leu,seq:cag)
     gene            complement(35448..>35882)
                     /locus_tag="IXT46_001537"
     CDS             complement(35448..>35882)
                     /locus_tag="IXT46_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAQ4947456.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        11868 a         6261 c         7406 g        10347 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttag aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggagggatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttatttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgctg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttactttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa
    26581 aaaccagaac atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc
    26641 aataaccaat caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt
    26701 ttttcttcaa atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga
    26761 atgttcctac aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat
    26821 atttgacgat cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa
    26881 actctgtagc gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag
    26941 aacgggatgt tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt
    27001 ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga
    27061 caataataaa ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga
    27121 aatttgcttc taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa
    27181 cgatcacttt aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag
    27241 aaaatgggtt taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga
    27301 taacgacatt gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg
    27361 ctaggatcaa atgaccagta ctactgatgg gcagccattc cgttattcct tcaataatac
    27421 cgagaatcac tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag
    27481 atacatctta tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga
    27541 aaaacttgag aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt
    27601 tcagactttg ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga
    27661 gtcgcgacta tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga
    27721 aaatcgaccg tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac
    27781 aggctgttta ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac
    27841 taaaacattt ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca
    27901 tacacggtct cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac
    27961 agcattagca atttgttcaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa
    28021 attcaataca cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc
    28081 gaaacaccat tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg
    28141 ttctcctaga ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa
    28201 tgaaaagtcg acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt
    28261 tgtgaggggt gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc
    28321 gtgtcgtacg atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac
    28381 gattgaaaaa aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg
    28441 gatagactgc aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt
    28501 gttctaaatt ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc
    28561 cagaaacgac aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag
    28621 ggacgacgcg aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg
    28681 caggcgagac aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa
    28741 tcggatcacc tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg
    28801 cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta
    28861 ccggctgttg gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt
    28921 caatgatcaa aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg
    28981 tttttaatct ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca
    29041 ttagtataac gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc
    29101 tgaattatca gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt
    29161 catagcattt taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc
    29221 ctatatccct gcctaatcag cagggtgttt ttttatgttt ggaaagagag ctctttttgc
    29281 taaactaggt tttttcaggt aatcttagag agaaagaggt ggtggaaatg atcaaacagt
    29341 caaaaatatc tgtgcggcac ttagtagaat ttattttgcg acgtggaagt atcgacaatc
    29401 gtaaaaaaag taaccatact gcattagaag gagcgagaat ccaccgcaag ctccaaaaag
    29461 atgcgggaga aaactatgaa aaagaagtct ttttaaaaac aacagttcaa ttagatgaat
    29521 attacctgat cgttgaaggc cgtgcagacg gtattttcaa aagagacggt atttattata
    29581 tagatgaaat caaaacctcc gaaccacgat ttgaagattt agaaccagaa caagtggaac
    29641 ttttctttca tcaagcaagg gtgtatgcct atatctatag tcaagaacat gatttacaag
    29701 aaataaatct gcaattgact tacttccaga cggcagaaga agtgatcacg agaaaggttg
    29761 aacatcagac aagagagcag ttagaaactt tttttaaaaa gctgactgaa gattataaag
    29821 aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa tgcctctttg atggctttga
    29881 aattccccca tgatgagtat aggaaaggtc agcgtgaact agcggtagct gcttataaaa
    29941 cgatccgtac gaaacagaaa ttgtttgtag aagcacctac cggaacagga aaaacaatct
    30001 ctacgttatt ccccgctttg aaagctgtag gggaagaaga gggagaaaag atcttttatc
    30061 taacggctaa aacaataact agacaagtag ctgaagatgc tatgacagca ttaaaagata
    30121 caggagctga agtaaaaagt gtcactttga cggcgaaaga caagatctgc tttttagatg
    30181 agacgacctg taatccagat cagtgcccat atgccaatgg ttattacaat cggattaatg
    30241 aaggtttatg ggatcttttg aatcatgaga atcagatcac tcgtgaagtc atcgaaactt
    30301 atgcaagaaa gcatacactt tgtcctttcg aactatcatt agatgtcagt atctggtgtg
    30361 acgtaatcat tggggattac aattatttat ttgatccaac tgtttattta agacgttttt
    30421 ttgaagatga aaaaaacgag gactatctgt ttttgattga cgaagcacat aatttggtga
    30481 atcgttcccg agagatgtat tcggcagaac tatcttatga aaaaacgaaa cgaagtaagg
    30541 aagctatacc aaaggaattc aaaaaacttc atcgccgttt caacaaacta ttaaaagaat
    30601 ttgattcgat ccgagaaata gcaaaagaag atcattggga ttatcatcat caaaaagcac
    30661 cggctgaatc tttagtaaag gcaggttatc aattaagcga aaaaattaaa gaatggctgg
    30721 cagaatttcc tgagcaccca tcacaagaac aattgcttcc ttattatttt gatttgcttc
    30781 attttttgaa ggtcagtgaa ttttatgatg atcactacga aacaacagtc gaaaaaacgt
    30841 atcgcgatct gatagtaaaa gagttttgta ttgatccaag cttgtttctt gagcagtcgt
    30901 tggataaagg aaaaagcagt attctttttt ctgctagttt ttcaccactc tcttattatc
    30961 aggaaacact ggggggacaa aaaagtctgg cttacaaact gccgagtcct ttcccagaag
    31021 gaaaccagca agttttcatc gcaaattacc tagagacgac ttatcgaaaa agggaacaca
    31081 gtctggcaaa attagtagag acgattcatg cttttgctga tggaaaggtc gggaattatt
    31141 tcgttttctt tccttcttat caatatttag atcttgcggt ggaagcattc agacagcaat
    31201 atcccgacag caatgtgcta atccaagaaa cggacatgaa tgaggaagaa cgcgaacgat
    31261 ttttaacaaa atttcaaaca aatcccgctg aaacattgat tggattttgc gtacttggcg
    31321 ggattttttc agaaggaatc gatttgagag gggaccgatt gatcggcagt atgatcgtag
    31381 gtgtaggttt gccgcagatg aatcatgagc aggaactgat caaatcatat tatgatgaga
    31441 aggaacacct tggatttgct tacgcttatc agcttcctgg aatgaacaaa gtcttgcaag
    31501 ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat cgttgtattg gcagatcaac
    31561 gattttctag tttttcttat cgacgtttat tcccacaaca ttggcaaaca gcaagagaag
    31621 tacgaagtgt tggggaattg gaagaaggaa tacagcgttt ttggttatca aaagaagcag
    31681 taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt ttttgattaa cgatagttag
    31741 tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa agcaatcaca gcttgtagat
    31801 catcacggtt cttacctgtc actctaatct gatcttcttg gatttgtgct tttactttca
    31861 gtttttcatt tttgatagct gtagtgattt tcttcgcgtt ttcacgatcg attccgttga
    31921 ccaaatcggc agtttgtcga gctttgccac ctagagcgtg ttctgattcg gaaaaatgga
    31981 tatttttgat tggcacattt cttttgatca gcttaccaaa taatacatct ttgatctgtt
    32041 cgattttgaa atcatcatcg ctcaatacaa ctagattgct gttctctaat ttgatttcta
    32101 ctgtagaatc cttgaagtca aagcgattgg acaattcttt tgttgtttgc tgaatcgcat
    32161 tttttacttc ttctgtattg acttctgata caatgtcgaa gctagcatct tttgccatag
    32221 gaaccctcct gatatacata taaatattta ccatacatct atcttatcat aggattaggg
    32281 cagattctta cctgtttgct aaaattcttc tcatttgagt tcgaagtatt ttattttaat
    32341 agataaactg ttattcttac atttggaata ccaaagtagg ggagaggtgc ttgtgagtaa
    32401 aattatgact gcgtatcata aaaatgaaag attaaagaaa atagtggtta ttttgataac
    32461 cggattgacc gctgcggtcg ctttaaatta ttttttgatt ccagccaatg tcttttctgc
    32521 agggatgaat gggatcgctc aaatcatttc ctcgctttta tatgaatggt ttcatatcaa
    32581 gatagacaca ggaacattta tttttctttt gaatatccct gtgtttgtat tagggtttct
    32641 caaagtagga aaacgagcaa cgatccttag ttttgtgaat gttgtatgtg tatcggtgat
    32701 gacgatgctg cttccagtcg gacagatcac tgataatatt ttgatgaatg ccctagtagg
    32761 cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa atgggcttta caactggtgg
    32821 gatggatatc atctctcttg tactttcaca aacaactgga aaaacagtcg gaaactacat
    32881 gctgattcta aatggtatca ttgtagtcat cgcaggcttc ttctttaact gggaaagtgc
    32941 cttgtatacg attatttcca tttatgcaat gactcaagta attgatgcca tccacacgag
    33001 tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca gaagaggtaa cagaagaact
    33061 agcaaaacgg atggtacgtg gaatgacatt actgccgtct gtcggtggct attcaaaaaa
    33121 acaagggaac atgatcatga tggtcatcac ccgctacgaa atgtatgatc ttgatcagat
    33181 cgttcatgaa atcgacgacg atgcatttat caatatttta ccaactcatt cagtatttgg
    33241 ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca actggcgtat tgccagaaat
    33301 aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt ttagaataaa tttaatctat
    33361 tacatctaat aagaacattt ttataaattt aaacgagaat cttacttcta aattctcatt
    33421 tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt gttaaggagt gtcgtacgat
    33481 gagcgaagca aaccaagaac ggtctggaca agaaatagaa ctaatcaaag aacgtattct
    33541 tgctgccttg gaaatggtga ttgatcctga attaggaatc gacatcgtca atttaggctt
    33601 gatttatgat atagaattca atcctgaaaa tggagaaaca gtcattaaga tgactctaac
    33661 aactatgggc tgtccattag cagatatttt aacagaatct atccatgacg cattaaaaga
    33721 agtgccagaa gtaacgaaag cagaagtcaa actagtctgg tatccagcat ggacgacaga
    33781 taagatgagc cgttatgcac ggattgcgtt ggggatacga tagaaatctt ggctgactag
    33841 ctatgagaag caaataggaa aaacaaaaaa gccttttatc ctttctagaa gaaaagagat
    33901 aaaaggtttc tttgtttata aaattttgtc tgctatatta taagttaatt aaataaatgt
    33961 gttctattga taaaggacat tcaaatccct ttccttttgg aatccttctt ttttacatca
    34021 gtttgatttt cgtatagtat tctttctcat cttcacgata aatcgcagcc ccattttttt
    34081 gttgtgcttt aagactgcca agattttttt tatttacaga caaaagtgcc tcatcaatgc
    34141 cgattttttt tgcctcttgt agtactaatg ctaatccttg tgtggcatat ccttttttac
    34201 gataattagg ggagatgccg taaccaatat ggccagcgcc gtttcttaat gtttcgttca
    34261 gtttatggcg caaattaaaa attcctacat actcatgttc atcactttct aaaataaaga
    34321 cggttgcggg aacgtaactc tcaggaagat cgattcctaa agacgttttt tcgcattttt
    34381 ttacataatc taaaaattca gcaaatgtat agccataagc attgttgata aatccactct
    34441 catttggtcc aaagctagtt tgtagctgat aagctttctt taaatctgct tcccatagtt
    34501 tgatcagttt catcgtattc acctctttaa gtaaccttat tcatttgttt tctactatag
    34561 cactattgtt gtaaatagcc atgcctattt ttatttattg tgtcatatcg tattaagaat
    34621 catcgaacaa tacaaatatg aattacaata aaaaaattat ttgaagttcg ttcattcgtt
    34681 acttatgatc tctagaagaa agaaaacgtg aattacttca gcgtctagaa ttccagaagg
    34741 atagtaatca acagaagaaa taatcaatat ccaaatgaaa gaagatagct gaatcgagaa
    34801 aaagaggaaa aaagaaatga agaaaaaaat aaaatagtta ctaatcccag agtcgttcgt
    34861 ttaacattga aatcgatcat atggataaaa cagatttttt caccaaccct caatagatga
    34921 tggagttgct cggatgaatt atttgtgtag atggcataag ggagggcgta cagaaatgaa
    34981 aaagaacaaa aatatgttct tgacaaaaaa cacatgtaat cctaaactaa aagatgtgat
    35041 gcggctatgg cggaattggc agacgcgcta gcttcaggcg ctagtgaggg tgacctcgtg
    35101 gaagttcgag tcttcttagc cgcataattt gtttttttat aaagagaagg tacacctgga
    35161 gcgatgagaa agaaaataac atattatcta aaagaatata ggaaaaattt taaacaacgg
    35221 aaccagattc aaataaatca aaaaaaattt gtgtgaaggt gggacagttt aaaacctaat
    35281 agattgattc aaatagtaga tttatagatt ctgatacaag aaatactggc aaacgatagt
    35341 taaggaataa agactaaact taaactcaaa aagaggtcat gcgaaagaat aaatcgcatg
    35401 acctcttact atattttgaa tgtgtttaaa cgttcaaata atgaatctta gtaccaaccg
    35461 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    35521 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    35581 tggtaacggc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    35641 gcgatccatt cttttgcaga gcttgtactt gctggagtag cagcagtttc tgttacagca
    35701 ggagcaggtt gtgtttcagc aacaggcgct gcttgtgttt ccgtttgaac cgtttcttgt
    35761 acaacaggtt gttcagcttg aacaggttca gcttggactg gtgcttcttg aacggctgct
    35821 tgaggttcag cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag
    35881 ta
//
LOCUS       DACGMI010000029        34667 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.030, whole genome shotgun sequence.
ACCESSION   DACGMI010000029 DACGMI010000000
VERSION     DACGMI010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.030"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(313..2205)
                     /locus_tag="IXT46_001538"
     CDS             complement(313..2205)
                     /locus_tag="IXT46_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947457.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2202..3929)
                     /locus_tag="IXT46_001539"
     CDS             complement(2202..3929)
                     /locus_tag="IXT46_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947458.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3945..4595)
                     /locus_tag="IXT46_001540"
     CDS             complement(3945..4595)
                     /locus_tag="IXT46_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4947459.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRVSRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4799..5095
                     /locus_tag="IXT46_001541"
     CDS             4799..5095
                     /locus_tag="IXT46_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAQ4947460.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5287..5907
                     /locus_tag="IXT46_001542"
     CDS             5287..5907
                     /locus_tag="IXT46_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAQ4947461.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5999..7165)
                     /locus_tag="IXT46_001543"
     CDS             complement(5999..7165)
                     /locus_tag="IXT46_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4947462.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7177..7530)
                     /locus_tag="IXT46_001544"
     CDS             complement(7177..7530)
                     /locus_tag="IXT46_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAQ4947463.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7658..8680
                     /locus_tag="IXT46_001545"
     CDS             7658..8680
                     /locus_tag="IXT46_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAQ4947464.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(9119..9553)
                     /locus_tag="IXT46_001546"
     CDS             complement(9119..9553)
                     /locus_tag="IXT46_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947465.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9663..11522)
                     /locus_tag="IXT46_001547"
     CDS             complement(9663..11522)
                     /locus_tag="IXT46_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAQ4947466.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11640..12800)
                     /locus_tag="IXT46_001548"
     CDS             complement(11640..12800)
                     /locus_tag="IXT46_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAQ4947467.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13107..14531)
                     /gene="araA"
                     /locus_tag="IXT46_001549"
     CDS             complement(13107..14531)
                     /gene="araA"
                     /locus_tag="IXT46_001549"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HAQ4947468.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DLVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14547..15245)
                     /locus_tag="IXT46_001550"
     CDS             complement(14547..15245)
                     /locus_tag="IXT46_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAQ4947469.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15202..16863)
                     /locus_tag="IXT46_001551"
     CDS             complement(15202..16863)
                     /locus_tag="IXT46_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAQ4947470.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17081..18481
                     /locus_tag="IXT46_001552"
     CDS             17081..18481
                     /locus_tag="IXT46_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAQ4947471.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18733..19812)
                     /locus_tag="IXT46_001553"
     CDS             complement(18733..19812)
                     /locus_tag="IXT46_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4947472.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIIEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19898..20857)
                     /locus_tag="IXT46_001554"
     CDS             complement(19898..20857)
                     /locus_tag="IXT46_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAQ4947473.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20869..22391)
                     /locus_tag="IXT46_001555"
                     /pseudo
     CDS             complement(20869..22391)
                     /locus_tag="IXT46_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
     gene            complement(22401..22964)
                     /locus_tag="IXT46_001556"
     CDS             complement(22401..22964)
                     /locus_tag="IXT46_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAQ4947474.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(22970..23833)
                     /locus_tag="IXT46_001557"
     CDS             complement(22970..23833)
                     /locus_tag="IXT46_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4947475.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23847..24743)
                     /locus_tag="IXT46_001558"
     CDS             complement(23847..24743)
                     /locus_tag="IXT46_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4947476.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24918..26189)
                     /locus_tag="IXT46_001559"
     CDS             complement(24918..26189)
                     /locus_tag="IXT46_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4947477.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26179..27696)
                     /locus_tag="IXT46_001560"
     CDS             complement(26179..27696)
                     /locus_tag="IXT46_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAQ4947478.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27894..28784
                     /locus_tag="IXT46_001561"
     CDS             27894..28784
                     /locus_tag="IXT46_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAQ4947479.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28857..29681)
                     /gene="nadE"
                     /locus_tag="IXT46_001562"
     CDS             complement(28857..29681)
                     /gene="nadE"
                     /locus_tag="IXT46_001562"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAQ4947480.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29693..31165)
                     /locus_tag="IXT46_001563"
     CDS             complement(29693..31165)
                     /locus_tag="IXT46_001563"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAQ4947481.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31802..32164)
                     /locus_tag="IXT46_001564"
     CDS             complement(31802..32164)
                     /locus_tag="IXT46_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAQ4947482.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32387..33139
                     /locus_tag="IXT46_001565"
     CDS             32387..33139
                     /locus_tag="IXT46_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4947483.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33279..34202)
                     /locus_tag="IXT46_001566"
     CDS             complement(33279..34202)
                     /locus_tag="IXT46_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4947484.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34217..34489)
                     /locus_tag="IXT46_001567"
     CDS             complement(34217..34489)
                     /locus_tag="IXT46_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947485.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10235 a         7214 c         5977 g        11241 t
ORIGIN      
        1 caagaggttg tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc
       61 ttctcaggtt tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
      121 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa
      181 tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg
      241 tttattcgga aaaagggact gtgacacgac ttttgtcaca gcccctaaaa aaaataataa
      301 atttgtacta ttctatgaag cttcttcttc agaaaactga ctgttataaa gatctgcata
      361 gaatccgtct ttttccatca atgtatcgtg gtttcctgtt tctacgatcg aaccatgatt
      421 catcacaata atgttgtctg catcgcgtat tgtagacaag cggtgagcaa caacgaaact
      481 tgtccggttt tccaataggc ggttcatcgc tttttgaatc agtatttctg ttcgtgtatc
      541 tacactagat gttgcttcat caaggatcag gacatctgga tttgctaaga atgcccgcgc
      601 aattgtgatt agctgacgct gcccttgcga aatattgctt gcatcctcgt ttaatacagt
      661 gttatatcct tctggcaatt tacgaacaaa atcgtctacg tgagcagctt tagcagcctc
      721 aatgatttgt tcgtctgttg catcgtcgtt cccatatttg atattgtcat agatacttcc
      781 tgtaaacagc caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt catcacgtga
      841 aagatcacgg gtatctacac catcgtaacg aatactacct ccagaaacat cgtagaaccg
      901 ttcaagaagg ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa tagcgaccat
      961 ctcaccaggt ttgacatcca agttaaaatc agtcattagc aagttatctg gtgtgtagcc
     1021 gaattgaaca ttttcaaaac gaactttgta tggtgtatct ttttcttctg gaaggccaga
     1081 tttttcattg gacatctctt cttcatccaa cacttcaaat acccgttcgg ctgaagcaac
     1141 tgttgattgg atagtgttca tcaaacttgc aagttgagtg attggttgag agaactgtgt
     1201 tgtatattgc aagaacgctt gaacatcccc taatgtcatg ttcccatttg caacttttac
     1261 tccgcctagt acagcgacga acacatagcc tagattttta acgaaattca tcaacggcat
     1321 gatgattgcc gaaataaatt gagctttcca accagcggca tacagattct gattttcttt
     1381 ttcaaatact tcctggtctt tttcagtatg attgaatgtt ttaacaatgg tatgaccacc
     1441 atatgtttct tctacttggt tattcaataa acctaaactt ttttgctgat ctgcgaaaaa
     1501 cacttgtgat ttcggcgcta cgatcatcac gatgatcaag cttaaaggga tcatcaataa
     1561 cgcgactaac gtcaattgcc agctgattga aagcatcatc acgatgaccc caatcaatgt
     1621 gactgcacta gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga tgttatccat
     1681 atcattgatt gctcgagaca tgatatcccc atttgtatgt gtatcataat aggaaatcgg
     1741 tacacgattc attttggctt ccaaatcatg acgtaattca taaactgttc gttgggaaac
     1801 acgtgtcata ataaattgct gtaaaaagtt gaatacagca gaaatcaaat acatcacgat
     1861 tactgtcgca atgatctgcg cgattttatc aaagtctatc ggaaattttg ttacttgttg
     1921 gccttgttgc atctgttgag cgccagccat tacacctttg aatatttctg tggttgcttt
     1981 ccccaagacc tttggtgttt ggatttggaa gatcacggct gctattgcta gtacaaatac
     2041 agcgatgatc gcaaccatac gtttagacat atagccaaac aatcggcgta ccgttcccca
     2101 gaaattttta ggcttttcac cttttacacc gagatttctg ccaggtccac catgtcctgg
     2161 accgcctgct ggtccatgag agggacgtgt gtttgtttta ctcatgctaa gtcctcctct
     2221 cttagttgtg aatgaacgat ttcttgataa gtttcgtttg ttgctaatag ttcttcatgt
     2281 gttcctttgc caaccagttt tccttcatct agcacaagga tcatatctgc atccattact
     2341 gtacttactc gttgagcaac taaaacggtg atactttctt tcatattcgt tttcaatgct
     2401 tggcgaagat tggcatccgt tttgaaatcc aacgctgaga aggaatcatc aaacacatag
     2461 atatctgctg ttttgactaa tgcccgtgca attgccagac gctgtctttg tccaccagag
     2521 aagtttcctc ctccttgttc cacatggcta tctaagccat cttccatctc tgaaacaaaa
     2581 tctttagctt gtgcgatttc taatgctttc caaatcattt catctgttgc atccggctta
     2641 ccatactgca tattgtctcg gatcgttcca gagaacagaa ctgctttttg aggaacaaag
     2701 cccattaatt ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc atttatttgg
     2761 atcgaaccag attcgatgtc atataatcga gggatcaaat tgactaaggt cgttttacct
     2821 gaaccagtcc cccctatgat tgcgacgatc tcgcccgact tggcttggaa atcaatatct
     2881 tccaatgcaa gtttttctgc tccatgatat cgataattga catgattgaa ggccaatgtt
     2941 gcgttttttc cagcaaaaga aactgtttta ggattttcag ggtcatggat accgattttt
     3001 tcatccaaca cttcattaat acggtcagct gaagcttgtg cacgaggcac catgataaaa
     3061 atagcggaaa gcatcataaa gctgatcaag atctgcatcg cataagtcat aaatgcaatc
     3121 agattaccga cttccaaagt catatctgct atgtagtgtc caccaaacca agtgattgct
     3181 acgtttgtac cgctcatgat caatgtcatc attggcatca tcaatgcgac gatcgtatta
     3241 actttgattg ccgtatttgt ataatcttta ttcgctaaat caaaacgatt ttcttcaaag
     3301 cgtgtcttat cgaatgctcg aatcactctg acccctgtca atccttctcg aaataccagg
     3361 tttaaacggt cagttttctt ttgcatactt ttgaataatg gaacagcaaa gtacatgatt
     3421 ccgccgatca aaataatcat tactgggatg acaactaaga agatttttgt caactgatga
     3481 tctttttgat aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt gatcatcata
     3541 cgtaaaaaca tttgtgtaac catttggatt tgagtcacat cattggtcgt tcttgtgatc
     3601 aaagaggccg ttccatattt atcaaacgca tcttttgtca gactctctga ttttttatag
     3661 acatccgtac gcaattgctt acccagtttc tgtgattcac gagtagcaaa aaatgtattt
     3721 gcgatagcag ctaagatact gatcaaagaa aagccgatca tcacaaaacc tgtatgccaa
     3781 atataatcga catctccttg cgctacccct ttatcaataa tattggaggt aagtgtcggc
     3841 aaatataaat ctgccagtac ttggatcacc atgaaaactg cagctgcaat tgctgaagtc
     3901 aaggagatcc gttttacgat ttttagcatc tagttccctt ctttctattt atatactccg
     3961 tttttcagcc aagaaagttt caaattgaat tcactgattg cttgctctac tgagtaatct
     4021 tcagatgttg aaaataagcg atacgaatgc gcaattgttg taaatacagt attcatcact
     4081 aattggatca gtaattccaa ttcatgatca ttttttactt tcagcttcgt ccgatcgatc
     4141 aattcaagca actcttttgc atcttgtttg tgttctttat gtggatcgtg aggcgttttt
     4201 tggcgactcg tatgaggagc gacttttctt gagacacggt aatccatgtt cataaacaag
     4261 ttacgataaa aagaagcatt ctcgccttcc aaaatctcat aaatcatttt agaaaaatag
     4321 gattcgaatc ctttgaatag atcaccatcg gattctttca ttagttgtaa catatcttta
     4381 gagctgtcac gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt atcttcaaaa
     4441 tactgataga aactgcctct agggatatcc gctaatttga cgatattagc aatcgaagct
     4501 tcttttaagg gtactctaga aaactcgatt ctcgcagcct cgattagtct tttttgtttt
     4561 tctttaggca aatggaaaaa tgtctgtgtc ggcatatgga ttctcctttc tttcaagatg
     4621 acacattgtc atatgacgct atgtcattat aacacctcct acctgttttg caagacattt
     4681 gcatagtttt tttcattatc atccgataca ttaaaaaagt gataagagga atccttccat
     4741 ttgaattaat gagagttgcc cattaaaata gccacatact aaacaaagga tgagataaat
     4801 ggcccaatca attagtgtcc aagacttcaa taaattgcct ctcgatgctg acagcatcgt
     4861 tttagataca agaaatacct tagattacac aaaaaaccac ttaagccact cgctttctat
     4921 ccccgctgct atcttgccaa gacaattaaa aaatctagat ccaaagaaac tttattatat
     4981 tctaagctat acaggcaggc gatcagaagc attagccgat caacttactg ctaatggttt
     5041 tcgtgctgtt tatatcattg gtgggatgga agctcttcag tcgagtgttg cttgaatatt
     5101 gcttgttaga ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct tttataccct
     5161 gtcttttttt agttatttat tcttcaacct tatcaatatg acttgatagc cttttctttt
     5221 tcgagtaaac tgattttgtt agtcatagtt ataacaatca tagcaataaa aggagaaggt
     5281 aagcatatgg catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc
     5341 acagttaagg cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa
     5401 gtgactgttt tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca
     5461 ggttgggaag cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa
     5521 aaaattgctc gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc
     5581 gcaaacgcct tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc
     5641 aatgtagctg gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt
     5701 aaaaaagcac tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct
     5761 caatatgtaa aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc
     5821 gaaggaatcg attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa
     5881 gctgctgctt taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag
     5941 gaaaaaatct tcaaagcagc atttgtgcct tggatatttt cccatctgtc tctttttgtt
     6001 attctttctg ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt
     6061 caaaaacatg agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac
     6121 cgatgattcc gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga
     6181 ttgctaactg attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta
     6241 ctgcaaaaac gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga
     6301 tagccggaat catcgctaaa aatgatccta agtaagggat caggtttaaa aaacccgcaa
     6361 taatccccaa cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga
     6421 ttgccacagc aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca
     6481 tttcactcag cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat
     6541 aaggtgctaa ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca
     6601 gagccactaa aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct
     6661 tagatatatc ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca
     6721 actgttcgcg aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa
     6781 tcgtatctac atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag
     6841 ggatgatcac tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga
     6901 tactgtaaag ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt
     6961 aatacaagat tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg
     7021 gtgcaaacaa atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa
     7081 caagtaaggc tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc
     7141 tgttcttctt attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc
     7201 caaaccaata gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc
     7261 ttctggacaa gcatcaaaaa tcaatgatac gtgagctact gtctctaaat tcccattggc
     7321 catcggaccg acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc
     7381 tttcaaagaa aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc
     7441 agctgttgct gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt
     7501 cccaatttct gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa
     7561 cagtataaca cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg
     7621 aaaactattt cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg
     7681 aacctatacg cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga
     7741 agaattagcc aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag
     7801 taaagctggc aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta
     7861 cgataaggat tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt
     7921 agcggttgat gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa
     7981 tgtctaccat atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga
     8041 agcgacaggt cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc
     8101 tgaccaacga ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc
     8161 cgaaaacggc aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg
     8221 ccatcttgtc tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac
     8281 agtccgcgtg ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc
     8341 gaccttgcca gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga
     8401 tggcaagttc ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt
     8461 tgaagatggt tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg
     8521 cgatttcgca ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa
     8581 tctgacatta tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt
     8641 ctatgtacca gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat
     8701 gaatcagcaa gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg
     8761 gaaaatcgaa gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca
     8821 gaactacttt gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg
     8881 aaaagaacat caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa
     8941 accgccgaga tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca
     9001 aggttgttgt tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa
     9061 aggtaatatt acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt
     9121 attttttcaa caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt
     9181 ggtcttgttt tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga
     9241 tactttggat catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt
     9301 tatgaatgcc cattgctttt gctggtggac gcaaagtact gactttcata agcattgccc
     9361 gatatttttt tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca
     9421 gttcacttgt ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc
     9481 cttctccgat tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa
     9541 tattcggtaa catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg
     9601 tttttatcct caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat
     9661 tcttattcgt gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca
     9721 tattggatca attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct
     9781 ttataccact gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct
     9841 aatgataaaa gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc
     9901 gctgcaaaat aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct
     9961 ttactgtcga acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg
    10021 atcgtatctg aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta
    10081 gaaagattct tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct
    10141 tgcagataat tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct
    10201 agattatcat actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac
    10261 tgaggtgttt tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa
    10321 atatatggat tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg
    10381 tcaaatccta atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg
    10441 atcgctgtcg tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc
    10501 atttttggta caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa
    10561 aaaccagtca atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc
    10621 atattgccac tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat
    10681 acttctacgc cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg
    10741 ttcggcgact cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca
    10801 gtgatttctt tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc
    10861 agattgtaca aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa
    10921 ggtatccata gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa
    10981 ttactgatat accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg
    11041 aatcgccttc cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt
    11101 cctgcggcag ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg
    11161 atttcagtga tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc
    11221 atataatttg caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg
    11281 acagatcctg ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag
    11341 aagaattttt ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca
    11401 ttttgacacc actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt
    11461 gctgctgttc cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc
    11521 aaatgcttgc tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta
    11581 cgaaattcga aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt
    11641 tatggccttt ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc
    11701 tgttgtttca cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag
    11761 acatgctcat tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc
    11821 agagaaaata tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac
    11881 ggcgcttgga aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac
    11941 aaaagataat cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga
    12001 gtcgatcccc ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct
    12061 ggaaaatcag tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat
    12121 ttatcaacaa tttcacttct tcctacattg ataagtacag catctttttt cattttttct
    12181 atattcgcct gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg
    12241 taatccgagg tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca
    12301 tcgcggatag aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt
    12361 gtgcctatcg ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca
    12421 taagcacttc ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc
    12481 atacgacttg cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct
    12541 tttactgcat tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct
    12601 ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt
    12661 gtaagccatt catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca
    12721 tctattattt tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca
    12781 atcaaatgaa cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc
    12841 aattagacaa ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt
    12901 aggctgagtg ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag
    12961 caaaatattg agggtgagat atcttgataa atggtgttcc gttagctgac attgataata
    13021 agactaaatt tcaaaaaagt tgaaaagcaa atttcgtcaa tctcttctta tttcttaaaa
    13081 ctaagtggct ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat
    13141 tttgcccacg tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg
    13201 ccacctgcct gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac
    13261 acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg
    13321 atcagcagtt tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct
    13381 ttcccatcaa atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca
    13441 acgattcttg gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag
    13501 attgcttctt ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc
    13561 cctcgagcca tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca
    13621 gcaaaaccgt atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt
    13681 ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg
    13741 cgaataccga tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca
    13801 taatcaccat agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct
    13861 tcgtctgata cgagatcgat tacttgtaca agatctccga taccaaaata atcaacagtc
    13921 caaccaaatt gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg
    13981 ttgtcaccaa aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc
    14041 atccaatcag caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta
    14101 ttttgtttat ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga
    14161 tttaaattca tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta
    14221 gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt
    14281 gagaaagtat gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc
    14341 atgatttttg tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc
    14401 aattggccat tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc
    14461 agtgcttctt ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca
    14521 atattcaaca taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg
    14581 tgttttcgta aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg
    14641 agctgtctgg taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc
    14701 gcactttgcg catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga
    14761 attgctaagg gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca
    14821 tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca
    14881 taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag
    14941 atcgtcgccc atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat
    15001 aaaacagcat gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg
    15061 tccaagtcca caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt
    15121 ttgataacga aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg
    15181 acgagtccgt gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc
    15241 agcattttct atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat
    15301 cccctcacgg taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt
    15361 gatggtgatt ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt
    15421 cccatgtcga tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc
    15481 ggctgtgtcc atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac
    15541 ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga
    15601 tttcaatata tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat
    15661 gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt
    15721 tactcctgta atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt
    15781 atcgccttct agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat
    15841 acccaaagaa ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca
    15901 gttattcgta tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc
    15961 cggatggaca ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc
    16021 cgaaatgttc cctgtccctt tggctacact gttcgtagcg accataccgg ttcctgcatc
    16081 cccttctggc ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata
    16141 agcccctgat tcgcttaact tgccagcttc ttctcctgct actagaactt taggcaaaat
    16201 gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat
    16261 ttcttgatgg taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac
    16321 gcctagtact ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa
    16381 attaatttct ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact
    16441 ccatctctgc ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt
    16501 gattgtattt cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag
    16561 ataaccgtgc atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata
    16621 gatttcgaat acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc
    16681 ttctaatgaa taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc
    16741 ggcaatagga gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc
    16801 aatccctaaa gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt
    16861 cataatgatt taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc
    16921 ttacaatgat tattgtatac ttttgtacgt acatgtcaag cagttattta caagaataca
    16981 ataaaaaaca cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg
    17041 atcaaccgcc ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt
    17101 ttcctcatcg tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat
    17161 tggtgttatg accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc
    17221 ttctttgata ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt
    17281 atctggtctt ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat
    17341 ttttatggct ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat
    17401 tgcagcaagg attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta
    17461 tatgtctgaa atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat
    17521 gattgcttct ggcatgctcc tttcctatgt tgcagattat ttgctaaaag ggttgcctga
    17581 aacgatggct tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt
    17641 cggtgtttta gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga
    17701 ggcaaaaaga gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca
    17761 aatccagctg aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt
    17821 agaaaaatat cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca
    17881 aggagctaat gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc
    17941 agcgagcgat gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt
    18001 gctctttttg gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag
    18061 cgtgatggga ctttctttca tcctaccagc tgttttagga actgtactgg atgctcatac
    18121 aaattcgttg ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg
    18181 ggctccactg acatgggtaa tcgtaggcga aatattccca ctagctgtcc gcgggcgagc
    18241 atctggccta gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc
    18301 tgtgatgact gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt
    18361 tttaggggtt ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga
    18421 aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta
    18481 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag
    18541 tcacaaggaa caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac
    18601 cagttggtag gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc
    18661 gatgacaaaa gctctcacaa acatcgcgac gagtaaccgt aggagcaata agaggcggta
    18721 aaaacccgtc tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc
    18781 atagagaata tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc
    18841 atcttgtccc aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg
    18901 gcttaaagaa gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt
    18961 ttctgtcaac ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc
    19021 taaagcttgt tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc
    19081 cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct
    19141 gataaaacct ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag
    19201 acgctgatgt ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc
    19261 taaacaaata taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat
    19321 gccttgttct ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt
    19381 aggctcaatg atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc
    19441 caattcgtga tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc
    19501 attttcgatt cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac
    19561 accgatcgtt tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata
    19621 tgtgcccgac cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg
    19681 ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt
    19741 tgtatttact tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg
    19801 atattttgcc atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg
    19861 caaggtttat tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt
    19921 caccaaattc tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat
    19981 taggattgtc taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa
    20041 tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat
    20101 ttttttcaga agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa
    20161 gattcttgtg ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac
    20221 cagaatacgt aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg
    20281 aaaaaccccg tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta
    20341 acgtccaagg attatccatt tcggatagat aaagattaga attcccagta atttcaggat
    20401 cttgttgggc ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac
    20461 tgaaagtttc ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat
    20521 ctatatgctg attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt
    20581 tatgattgct tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg
    20641 cccagatcaa ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag
    20701 catgttctaa ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa
    20761 ccgatcctgt aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt
    20821 gccgaacgat aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt
    20881 tattctaatt acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc
    20941 tattgaaaaa tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc
    21001 caacagatcg ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg
    21061 ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt
    21121 gccgttatct acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata
    21181 aacagggcaa atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg
    21241 catcacataa taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg
    21301 tattgtgttt actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat
    21361 agccagccct aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat
    21421 gggactaccg acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc
    21481 atcaaacgct agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt
    21541 agcaacgatt tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt
    21601 atcatcacgc tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata
    21661 gttatgcaaa gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca
    21721 ttcagggtac gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc
    21781 atccactaac ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact
    21841 cttagccccc acttgccatg gacctctagc tcattcccta aacaccataa tttaacgcca
    21901 aaaggctttt tttgcccatt ttttattctt aaatcactcc agaaggttcc ttttggaaaa
    21961 ttacaatatt ctactaaatt ttttgcttca tcaattcctt ttgttcctaa attcaccgtg
    22021 aatatcggtt tcgcttgtac atgactgatc catttaaaaa attcgtggag tccaaaagaa
    22081 tttggttcta tacctcgcca tgctaaatca attttttttg gtcgttgttc tttcctacct
    22141 acagtatcca cccaatcata accagatgta aagtttcctc caggatagcg aatgacacct
    22201 aattctaatt cctttacata agagaggaca tcttgtctaa acccgtcacc atcagctgtt
    22261 tcatggcccg gttcataaat ccctgtatag acgacacttc ccatatgctc aacaaatgag
    22321 ccaaacagcc gagaactgat ctctcctacc gtaaaatcct ctctgatttt tactttcact
    22381 tcttcgtcca acagctttcc ctacctttca tttcctatag tcaagataat agatacaagt
    22441 ttccatacgc caccagcaaa gataaaaata aaaggaggga aaagaaatat gagcagtaca
    22501 aatcctaata acaatacgca acaaagaata tttctcaaaa aatcaaaaaa tactttccat
    22561 gcactttgtt caaaaatttg taaaaatgtg atatctttgt tttcagaaat cacatatatc
    22621 caggataaaa gaaacatgga ataaataagt aaaactacat atccactaat tgaaagtacg
    22681 attgtctgtt cttctaataa ttgattaaca agaaaataaa taatgatcgt taacagacta
    22741 aggaacaagt tcttaccaaa atgttgcttt attccttgaa agaaaaaata aatgatattt
    22801 cctgatccct cacctttcca ttgcgccatt acataaaaaa cagcacatgt agcaggcacg
    22861 atagtaataa caggcaaaca cacgattacc cagagaatac ctaataagat gtaatcagaa
    22921 accacaatca actgtccata aaatttagtc tcaactattt tcatcttcct cactctttca
    22981 ttccagacat agctgttcct tgaacaaaat atttctgtgc aaaaatataa accactagta
    23041 atggcagcat tgaaataacc gttccagcca ttacaggtcc ataaaaagaa atgttctgcc
    23101 ctgtaaataa agctaaccct gctggtaaag ttctcatttt tgaactactt gtcaatatca
    23161 atggataaag caagtcattc caactattca tcagcgtgaa aatccctaat gataaaagag
    23221 taggtttgct caatggcaac atgattttca aaaaaatatt aaactcactt aatccatcaa
    23281 tgcgtgctgc ctcttccaaa gaatctggta aagtaataaa aaacgaacgc atcatgaaga
    23341 taccaaatgc agttgtcata cgaggaatga tcaaacctgc ataagtatca agcatgccaa
    23401 gcaaattgac ttcaataaat agaggaatca tgaagacttg gaatgggatc atcattgtca
    23461 gcaaaacgaa atagaacaaa actgattttc ctttgaaacg catacgagca aatgcatacc
    23521 ccgcaagaga atcaaagaat acagaagtga tcactgtccc tccagcaaaa atcactgtat
    23581 ttttgatgta atctaataaa gggatcgttg tccaaacctt aatatagtta tctagggtat
    23641 agctatctgc aaatattcta ggcggaaatg agataatgtc tttttcgtgt ttaaaagaag
    23701 aaataatcag ccacaaaaaa ggaaacgcaa taaccaacaa tataactagc atactaatcg
    23761 ttcgaatgat ttttttacca ctaactgctt ttcgactatt cacagtaact gtaatcgagc
    23821 tttctggtgc catacaggtt tccctcctat ttcatttgtt tttctttccg tgacatgtac
    23881 acattagtgg agatagctat agttgcaaca atgataaaca aaaccgaaga cagtgctgat
    23941 gcatagccca attcataagg tgctgtaaat cctcgactgt aaatatattg aacagctgtt
    24001 tctgtcttaa attgtgggcc accagcggtt gcaacatata cttggtcaaa cacttgcatc
    24061 gaaccaatca gattcgttaa aatacaaaaa cctaaggagg gaacgatctg aggtagcgta
    24121 atgttaaaaa actgctgtcg atttgttgca ccatccattt gagcagattc atacaaagag
    24181 ggagagattc cctgaatagc agtcaagaga atcgtcatag taacaccaaa attcttccaa
    24241 acagtcatga tggctaccgt cggcatagca agggttggat cgcgaaaaaa ttgagggatc
    24301 ggcaagccga cttgtgaaaa caagtaagga atcgccccta cattcggatc aagcaacata
    24361 gaaaaaataa tcgcaattga cgtcaatgaa caaataactg gaatgtaaaa tgtcgaacga
    24421 caaaaacgat tgaatctggt atttttagat aatgctactg ctgctaataa accaacgata
    24481 atttgtgttg gcgtttcgag tacggtgaaa tataaagaat gaatcaacga attaactgct
    24541 cgttcatcac taaatatacg tgtgaaattt tcaaaactta caaaatttct tgatgtaaag
    24601 aaaatattca aatctgtaaa actaatagca aatgttccta aaagcggtat gacagtaaat
    24661 aataataaaa ctaaaaaaga tggagttaaa aacaaatacg cagcacgatc aggacgattc
    24721 caatatttgg tgaatccgtt catatagtcc acctcatctt tcattttgat aaaatataca
    24781 atcttggttt aaacgaatct gaataagata tccgaacaat cgctgtgatt tttgcaataa
    24841 cacctatctg caaatactag gtcgatcatt cagatatctg tatcttgcca acagtctatc
    24901 ctgtataaag ttctgtacta tttttgcagt aattgattga tggcatcatc tgcatcgttc
    24961 atgagtgtct caggatcttc tcctgctaat aatttttcaa tcagtggatt gatgatatcg
    25021 ttattgatcg cagagatttg ggtaaaacct ggtaaatatg gctctgcata gtccatttgt
    25081 ttcgataatt cagatacaat aggatcattt tttacttctt catcttttgc tactgaatcc
    25141 aagtaggcag gaaaaccatt ttcgatactc cattttttac caatttcagt tgtattccaa
    25201 tatttcaaaa actcatagac agcttctttt ttattattat ctgtacttgc cggaatggca
    25261 tatcctacgc catctaaaat agctgttttt ttgtctgaat cactcccttg tggtaaggta
    25321 gtcacattat aatcaatctc gtttgctttc aatccgttat ttaaccatgg cccattgatt
    25381 tcaatggcta gttgaccagc attcattaaa ttgtccattt cggcgccaga aatcgattct
    25441 ggaccagtct tgtctacatg gatcattttt tggatcgctt ttaacgtttt aaggttctca
    25501 ggagacgcaa attcagactt agtataatca tcgttcacta atttaccgcc atttgctaac
    25561 atccagttat ataacggtgc agttccatcc ttattgaaga caaaacctga tacattttta
    25621 ctactatcag ttaattttgg tgccatttct gtcaattctt cccaagtagt aggtggttgt
    25681 tcagtatcta atccagcttg tttaaacaaa tcattattcc aatacatata catgccttgt
    25741 acctgcatgg ggacaaaata ctgtttacct tctacttcac ctaattcaat agccgtttct
    25801 ttaaaatcag atttatctac tccatcatat tcccagaaat cgtctaatgg ttgtaccgct
    25861 ccgttttcta catactgtgc aaaatctgga taatttaatg caataaagtc aggtgctttt
    25921 ttagaagaaa tcgctgtagg aagtttttca ttcaaattgg cccaagtcat gatatccatt
    25981 tcaattttga tgtttttatc atttgtttta ttaaattcat taacgatttc ttgcaatatt
    26041 tcaccatcag atgcagtaaa cccattccaa aaagtcaaag tcacttcttt atcagaatca
    26101 gattctgctg aacttccgcc accgcaagct cctaaaatac ctgttgcagc taccaacaaa
    26161 gagccaatta accatttttt acctttcatt ttttgttcct ccttcatctg ataaacgaca
    26221 tctgaccaca ttccaagata gcggtttcaa taaacaattg attttcccat cttcagcttt
    26281 tacatttgtt gaatgacttg gttttacttg ttcactttta ggaagattag ttgcttttgt
    26341 atcaaatcca ctcatttcag aaaaatcaat cactccctct aatgataatt cagacaagtg
    26401 aacagttaga ttcatttctt cttctccacg gttaactgca aatatgacaa gttctttgtc
    26461 atttattacg gctatacttt ctaaatacgg cacttcttca aaatcttccg tcgcatagtt
    26521 tgctgaacga atttgtgggc ttaacacctc tccttgtcca tacacagcag cttgcataaa
    26581 tggataatag atcgtctgtc tccaagcttc tccgtttgtt tctgtcctga ttggtgcaat
    26641 aacgtttacc aattgagcaa gacaagcaat ctttactcta tctgcatgtt tcaataaagt
    26701 gattaataga cagcctaata gtaatgcatc ttcaaaatta tagttatctt ctagtaaagg
    26761 aggagcaatc tgccaaggcg ctgcttgctc atcttgttcc gctgaatgat accaaatatt
    26821 ccattcatca aaggacaggt tgatctgctt cttactatgt ttcttcgcct tgactgtatc
    26881 gcacatcgct gtcacttcag aaatgaaccg atccatgtct aaggaacgtg caagataatg
    26941 agaaagatca tttttttggt tgccataata ttgatgcaga gacaaataat ctatttgatc
    27001 gtacgcttga tcaagaactg ttaactccca atcaccaaat gtaggcattt gccgattcga
    27061 acttccgcat aaaaccacct caattgaatc atctacgagt ttcatcgcct tagccgtttc
    27121 ctctgctaac cgtccatatt cttccgctgt tttatgtcca atctgccaag gaccgtccat
    27181 ttcattccct aaacaccatg tcttaattcc aaaagggctc tcttgaccat tcgaacgcct
    27241 taaatcactc caataagttc ctttaggaaa attacaatat tcgactaaat tacgagctgc
    27301 atctactcca cgagtaccca gattgacagc catattgatt tcggccccca catgctgaca
    27361 ccagttataa aattcatgaa tcccaacttc attcgtttca attgtccgcc aagctaaatc
    27421 caaccttcta ggtctatttg ctatgggccc aatactgtct tcccaacgaa atcctgacac
    27481 aaaatttcca ccaggatatc taatcatggg aatgttcaat tcttttacca agtgaatgac
    27541 gtcttggcga aatccacttt tattagctga tggatgatct ggctgataaa tcccttcata
    27601 tactgctcgt cccatatgtt caataaatga actgtacaac cgcggatcaa ctttgcctac
    27661 acgcttgaca ctactaatca acattgtggc ttccataact gacctccttt aatttataca
    27721 tgaataatac acctcgttga aagcgttgtc aataatataa atgttaaact tacttatttt
    27781 ttatcgattt taattaacca aaatattaat aatgattaaa acaaataatt taatataact
    27841 tttattaaca aatatgttaa tatataagaa aaacctttta agaggtgata tatatgcaac
    27901 tacaaataaa cgaagaatcc ttaccggtat atgaagcatt agctagtaaa acaaggatca
    27961 agatcatcca gctactttcc aaaaaaaaga tgaatgtcaa agatttggca aaagaacttg
    28021 gagtgagcag tgctatcacg acgatgcacg tgaaaaagct agaggaagca aacatcatca
    28081 aaacagaaaa agtaggacaa caaaaaattt cgagccttcg tgtcgataaa atcgatatta
    28141 gttttccaga aaaaatattc aatgcttttg atacgaaaga aacatcgata cctattggtc
    28201 actatacaaa ttatgcaatt gaaccaacat gcggtttagc tacgatccat gattttatcg
    28261 ggaaagtgga tgaaccacgc tattttatgg atcctcgaag gatggatgcc cgcattctct
    28321 ggtttaccag cggatttgtc gagtatcagg cacctaattt tttaaataca gaggatacat
    28381 tggagatgtt ggaagtttct gtggaaattt cttctgaatt tcctttttca aatgacaatt
    28441 ggccttcaga tatcactttc agcctaaatg gtgtggagct aggaacatgg acgagccctg
    28501 gagattttgc tgatatccgc ggtaaatata cgcctgattg gtatccagat aatcttaatc
    28561 aatacggctt gctgaagacg atccgaatta ccaaacactt gacgaatatg aatggagaac
    28621 ccttgtcaaa catcacgatc aacgacatcc ctaaagagca agacacttgg catttgcgaa
    28681 tcgaagtgaa agacgatgcc aaacatgtgg ggggctgtac tttatttggt aaaggattcg
    28741 gtaattacga tcaggatatc aaattaaaag tttactacag ctgatatttt tcttttctat
    28801 tttataaaac aaaaacagcc aatccctatg aagggacggc tgtttttgct ttattgttat
    28861 ttccagaaat catccaaaac ggaaattggc aaatgtcgtt tatgttgtgt cttgttccac
    28921 catgcttcga ttttttcttg tgcttgagcg ggaacttctt ttccttctag ataatcatca
    28981 atttcattat atgtgacacc tagtgcgact tcatctgcaa tcattggttt cccatcttca
    29041 agatctgcag tcggaatttt tgtgtataat ttttccggtg cattcaatgc ttgaagcaat
    29101 tgtttccctt gtcgtttgtc caaacggaat aatggcaaaa tgtcggctcc accatcacca
    29161 aatttcgtga agaatccagt aatgttttct gcagcatgat ctgtccctaa tacggctcct
    29221 gctctttctc cagctacggc atattgcgta atcatacgtt gacgtgcttt gatatttcct
    29281 ttgttaaaat cgctgattcc cacacctgct tcgcttaata cttgtacttg tgcatcaaca
    29341 gctggtttga tatttactcg cagactaaca tcgggctgga taaagtcaag agcagctttt
    29401 gcatcttctt catctgcttg ttcaccataa ggaagacgaa cagcgataaa ttgatagttt
    29461 tcatcttttg tttcttcacg catttcttcc atcgttagtt gcgccaaacg gcctgctaaa
    29521 gtagaatctt ggccgccgct gatacctagt acaaaagttt taagaaacgg atattttttc
    29581 aaatatgctt tcataaagtc aatactttta cgtatttctt cttttggatc aattgttggt
    29641 ttgacaccta attcattgat aatttctgtc tgcaggctca tttattctcc tcctatgctt
    29701 ctgtatgaag ttctgctacg ctttttttca ttcgttccat gatagccatt ttatggttcc
    29761 agcattcagt agacagatcg actgggtatt tttgcggatt caagtctcgt ttatactctt
    29821 cccatagtga atctagattt tcttttgtat attctttgat ttcgtttagt gcaggtaatt
    29881 cgtaaactct ttttccttcg ataaagatat cttgtaaaac tgggcgagct gtaaagtctc
    29941 gaacagtttt attgataaac gtatgcactg gatggaacat gaagatagct tcttcttctc
    30001 gagggtcttc atcccataat gtcacgtagt ctccttcaga tttcccatca aaatttcgag
    30061 tgatgcgcca cacttgtttt ttccctggag tagttacttt ttctgcattg cttgataact
    30121 tgatcgtatc catcattttt ccttcatcat cttcgatcga tactagcttg aatactgcac
    30181 caagggctgg ctgatcatag gctgtgatca attttgtccc aacaccccat acatcaattt
    30241 tagctttttg catctttaaa ttcaaaatcg ttgcttcatc caagtcattc gaagcataga
    30301 tttttgcttc cgtaaatccg gctgcatcta attgttcccg aacacgctta gatatatagg
    30361 ccatatctcc actgtcgatg cgtacgcctt ggaagttgat tttgtcacct aattctttcg
    30421 ccacgcgaat cgcacttggc acacctgatt tcaacgtatc ataagtgtcg actaagaaca
    30481 cgcagtcttt atgggtttta gcgtaggcca taaatgcttc ataatcattt ccataagatt
    30541 ggactaacga atgagcatgg gtcccgctag ctggtatccc aaatatcttc ccagcacgta
    30601 cattgcttgt tgcatctgct ccgccgatat atgccgctct agttccccag actgctgcat
    30661 ccagttcttg tgcccgtcta gttccaaatt ccaatagtgg atcttctccg atgacagatt
    30721 tgatacgagc tgcttttgtc gcgatcaacg tttggaaatt gaccatattc aacagtgctg
    30781 tttctactaa ttggcagtgc gctaaaggcc cttccacttg gatcaatggt tcatttgcaa
    30841 aaactagttc tccttcacga gcagaacgaa ctgttgcttt aaattcaaaa ttttgtaaat
    30901 actccaaaaa accttcagga tagacttcta atccacgcaa gtaagcaata tcggaatcat
    30961 tgaacgtcag attctctaaa taattgacta accgttccaa tcctgcaaaa accgcgtatc
    31021 cgtggttaaa aggcatttct cgaaagtaac attcaaaaac agcatgtaaa tcagctcgac
    31081 ctaattccca gtatgtctgc atcatattga tttgatatag atccgtatgc agcgtcaaac
    31141 tgtcgtctgg gtaagtatta ttcatcttgt attactcctc ttggcaagtt ttcatttcct
    31201 acccattata acaaaaaaaa ttaataggaa aagaaatctt ccattttttc tgaaaaagca
    31261 catgttttac ggatatttct tgctaaaaat gaactccatc tgctaaaact atcctttctt
    31321 attggtattt aacctaaacg agaaagaata cttattttat tcaatgtatc cgagacacga
    31381 agaaattagc gttttctatt tttcttactt gataaaataa gtagattttc ctactacaat
    31441 cgtagccgtt aagataccga tgattgaaca aatataacca aatgtctcta caacataatc
    31501 aatggcaaaa gtttttgaag caataatacg tctttccttt tttgcttctt atccccaaag
    31561 aaacggatat aacttattat gtattgaatt tttttggaaa ggcgaattat gacaagatat
    31621 accttgcgtt gaaaaaactc gcggaaaaaa tatcacacgt ttttaaaaag atacaaagta
    31681 agaaagcagc tgtcaataga atggaaacaa aaatggcgag acatcaatca gtctcgcctt
    31741 gttttttatt gtatacatta gatatggagc aggttaccat aaagatgatt attagtcgtt
    31801 attaaataga atccttcgta tttttttgtt ctatcactac aatatcttta tttggacgtt
    31861 tgaattgtat tccggcacgt tctagctcct gtttcactcc tacatggact ttgacatctt
    31921 ctcgtgtcat ttttaaaacg tgatgaatcg catagtcgat ttcttgcctt gtgatttttt
    31981 tcttcgtatt gatcatcacg acttgctttt tatcatatgt gtctaccaat agcagttgtg
    32041 ttcgatctaa cgaaaataat ttgtaataat taatagccgt attcccaaaa aagaattcca
    32101 ctactttagg ataaaatgtc ttaatattta aattactatt cacaggtgtt tcgattagct
    32161 tcatctcatt cctcttttct atatagtcga tttagatcca atcttaagtt atgttaccat
    32221 ctttcctagc attaaggaat cggttacaat tgaaccttta aagacaaaag gatttacctt
    32281 ttatcactta atagtataac ataatttcat gagaaaaaaa tacaattttt tcttgaccat
    32341 ctcgttacgt aaaggattat gcttacattt gtcaggagga aaaataatgg agtacacaat
    32401 aaagaaaatg tcagagatat caggagtcag tccgagaacc ttgcgctttt atgatgagat
    32461 tggactgcta aaaccagcta ggatcaattc ttcaggttat cggatttatg gcaaaaaaga
    32521 agtcgatcgt ctgcaacaca tcttatttta tcgaacaatg gcattcaagt tggatgatat
    32581 ccaagaggtc ttagacaatc catcttttga ccaccagaaa gctttaatca agcatcagca
    32641 aatgttgctg gaaaaacggg cacaaatcga taccctcttg acaactgtcc aacagacact
    32701 tgatatgtac gaaggaggaa gaaaaatgag tgacaaagaa aaatttgaag ggtttaaaca
    32761 acaaaagttg aaagaaaatg aagaatccta tggacaagag attcgacaaa aatacggaaa
    32821 aaaaaaggtt acagcatcca atgaaaaatg gatgaatatg gataaagaaa cgtatgaaga
    32881 aatgcaaact gttgaaaagc agatgttatt tgatctcact ctttacttaa aagaaccaga
    32941 agatgaaagc ttagcagacc gtatcttcca agctcataag aagtggttat cttacagctg
    33001 gcctgaatat cagccaaaag cgcataaagg actaggaatg atgtacgaag ccgatgaacg
    33061 gttcactgca tattatgacg agcgaagtgg tcatggtgca gcaaaagctt taaatgaaat
    33121 tatccaaaaa aaggcgtaat cttttacatg atccaacaaa aaagtacacg taaaatgacc
    33181 taataacaaa acagcagaca cccaagttag atttttatgc taacttttgg tgtctgctcc
    33241 attctttcac aagttttttc atcctacttt aaatatattc atcgttgaat aaacgtataa
    33301 ggtattttca ctttatcctt tttttctgta agaaacaatt gaaatgccat ttctccgcaa
    33361 gcttccagat ggtggtcgat ggttgggaaa ccaagaagct cgctgatcag caaattatcg
    33421 cgtccaatca ccactggtgt cttatcttgc agatagcttt gcaagatgcc tgctgcaacc
    33481 atatccgaat ttgtaaagac accatcaact ccaagctctt taaaaaagaa gcctgcttgt
    33541 tttcctttct ctgcatctat acaatcccaa aaaacaagtg attcatcaaa agatggaaaa
    33601 agttgatgac atagctgcaa agtgattttt gagttataac ttagcctgcc acttcgcccc
    33661 aacgtgatgc ccaattgctt tataccttgc tgcttcaaat aagtaagacc ttctgtaatt
    33721 gattgttctc gatcaataaa gacacagctt gcctgttttc ccttgatttc ttcacaaaaa
    33781 actagaggtc catatttttg atatgccaat aaatcatcta gtgtattggc acgagacgta
    33841 atgatcaatc catcgaaagc tttagctgca aattcttcaa gataccttcg ctctttttct
    33901 ttctgatagc ccgtcggtaa aagtgtcact ttgtaatcat aatcaaacgc tgcttcaatg
    33961 atcccactga tcaactgatc aaaatacgga tgattggtat aaggcagaat cactccaatg
    34021 cttttcgttt ttccataact taactgtctg gcatttgcat tagggatata atcgacttct
    34081 ttcatgaccg caagtatttc tttccttttt tcctcatcta catatggatg tccattgatt
    34141 acacgtgaaa tagtagaaac tgaataacct gtgagctttg cgatatctcg aatgtttgcc
    34201 actgctgctt cgccacctat acaaaaagat tttcttgtaa atagtctacc acagctggac
    34261 cgcattcaaa aaactgatac atttttcctt catgcgaaaa actgatccgc tgcccgcccc
    34321 aatatatatc ttttgtcaaa ttttcgattt cattcattgg tatttctttt actatattcc
    34381 tattcaaccc ttgaaaactg tacaacgtta atacggatcc cttgaactcg acaaacgcat
    34441 aaaaataatt gttcgttgtg ccatctgtta tctctacata agtattcatt gcaagccctc
    34501 cttttgatac tttgagtata gtgtatgaaa cgcgtctcat agcaaggagt ttgttttgcc
    34561 aaagaaaagt tttattcctc tttcattatt accaaagtct cttattttaa attgaataca
    34621 ttataatgat actgtaaata tatctttatt attagtgaat ggatatt
//
LOCUS       DACGMI010000030        34667 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.031, whole genome shotgun sequence.
ACCESSION   DACGMI010000030 DACGMI010000000
VERSION     DACGMI010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.031"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..303
                     /locus_tag="IXT46_001568"
     CDS             <1..303
                     /locus_tag="IXT46_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4947486.1"
                     /translation="LGVKGQNLLADDSFWQIEAFYLAQCAYNTTLMLSPDRIIFGGGV
                     MKQEHMKKKVQDKFVELINGYVEIPPIASYIVTPELGDSAGIIGGLALARKAIRNK"
     gene            complement(1794..2459)
                     /locus_tag="IXT46_001569"
     CDS             complement(1794..2459)
                     /locus_tag="IXT46_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4947487.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2585..4621
                     /locus_tag="IXT46_001570"
     CDS             2585..4621
                     /locus_tag="IXT46_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAQ4947488.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4625..5263
                     /locus_tag="IXT46_001571"
     CDS             4625..5263
                     /locus_tag="IXT46_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947489.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            5291..5719
                     /locus_tag="IXT46_001572"
     CDS             5291..5719
                     /locus_tag="IXT46_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947490.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            6176..7087
                     /locus_tag="IXT46_001573"
     CDS             6176..7087
                     /locus_tag="IXT46_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4947491.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            7304..7741
                     /locus_tag="IXT46_001574"
     CDS             7304..7741
                     /locus_tag="IXT46_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947492.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            7836..8720
                     /locus_tag="IXT46_001575"
     CDS             7836..8720
                     /locus_tag="IXT46_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAQ4947493.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            8944..12084
                     /locus_tag="IXT46_001576"
     CDS             8944..12084
                     /locus_tag="IXT46_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947494.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEIT"
     gene            12131..12676
                     /locus_tag="IXT46_001577"
     CDS             12131..12676
                     /locus_tag="IXT46_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HAQ4947495.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            12704..13159
                     /locus_tag="IXT46_001578"
     CDS             12704..13159
                     /locus_tag="IXT46_001578"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HAQ4947496.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            13156..13914
                     /locus_tag="IXT46_001579"
     CDS             13156..13914
                     /locus_tag="IXT46_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAQ4947497.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(14000..14740)
                     /locus_tag="IXT46_001580"
     CDS             complement(14000..14740)
                     /locus_tag="IXT46_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4947498.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            14801..16054
                     /locus_tag="IXT46_001581"
     CDS             14801..16054
                     /locus_tag="IXT46_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4947499.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLIGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            16339..16602
                     /locus_tag="IXT46_001582"
     CDS             16339..16602
                     /locus_tag="IXT46_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAQ4947500.1"
                     /translation="MEKQANPYDHKKMLTQQLRELEQDESIHRKAYNQVPPKVEYSLT
                     EEGKSLREILVALSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            16725..17051
                     /locus_tag="IXT46_001583"
     CDS             16725..17051
                     /locus_tag="IXT46_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAQ4947501.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            17119..17832
                     /locus_tag="IXT46_001584"
     CDS             17119..17832
                     /locus_tag="IXT46_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAQ4947502.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            18142..18993
                     /locus_tag="IXT46_001585"
     CDS             18142..18993
                     /locus_tag="IXT46_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4947503.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            19114..20979
                     /locus_tag="IXT46_001586"
     CDS             19114..20979
                     /locus_tag="IXT46_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4947504.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            20993..22435
                     /locus_tag="IXT46_001587"
     CDS             20993..22435
                     /locus_tag="IXT46_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4947505.1"
                     /translation="MQSRFSEKFLWGGATAANQLEGAYDRDGKGLSVADAMPGGKQRF
                     AIIGSEEFDWTIDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPN
                     GDEGTPNEAGLEFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYE
                     RFAQTVLERYSSKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVA
                     SSKAVKIGHELRSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGE
                     YPAYTARTHKKYGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSE
                     GNLLGGVKNPFLEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDG
                     TIIDDYRIDYLRRHIEAMANAVADGVDLMGYTPWGCMDLVSASTGEMSKRYGFIYVDL
                     DDEGNGTLNRSKKKSFDWYKEVIASNGVNL"
     gene            22543..23244
                     /locus_tag="IXT46_001588"
     CDS             22543..23244
                     /locus_tag="IXT46_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4947506.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQEILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            23416..23895
                     /locus_tag="IXT46_001589"
                     /pseudo
     CDS             23416..23895
                     /locus_tag="IXT46_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            23906..24412
                     /locus_tag="IXT46_001590"
     CDS             23906..24412
                     /locus_tag="IXT46_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lyxose/D-mannose family sugar isomerase"
                     /protein_id="HAQ4947507.1"
                     /translation="MDYKKRVQQMFLDSGVVLKETELERIEYTDFGLGAIETEGLNLF
                     VYENNERYCGKELVLLPYQTCPEHRHPPRDENEGKKETFRCRKGLVYLYVEGKETKKL
                     SCIIPKGQERYYTAKKEIILHAGDQYTIEQNIKHWFQAGATGAVITEFSSSSDDPSDS
                     FTNPAIYR"
     gene            24823..25398
                     /locus_tag="IXT46_001591"
     CDS             24823..25398
                     /locus_tag="IXT46_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAQ4947508.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            25398..25838
                     /locus_tag="IXT46_001592"
     CDS             25398..25838
                     /locus_tag="IXT46_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HAQ4947509.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTITSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVLAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFEKLPVETYVGEYL"
     gene            25854..26555
                     /locus_tag="IXT46_001593"
     CDS             25854..26555
                     /locus_tag="IXT46_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAQ4947510.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDTFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(27053..27478)
                     /locus_tag="IXT46_001594"
     CDS             complement(27053..27478)
                     /locus_tag="IXT46_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947511.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DITNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGADSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKEATVTFTKIGNYRLKDKDGNIYSL"
     gene            27709..29034
                     /locus_tag="IXT46_001595"
     CDS             27709..29034
                     /locus_tag="IXT46_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4947512.1"
                     /translation="MKVVDRLSEKMLPIVSKMSSQRHLLAIRDSFIVTMPLVMAASVM
                     VLLNALIFSNATVQRILDLSPLAELASIVNNGTMSILAIIVCYNIGWNLATHYIQTGV
                     IDDPSFSPVHAGILSTAVMFILMSLSSTVTLMDGNTAEATGVFLQSLTSSSGLATAMI
                     AALVSTELFIKLAKMKSFKIRMPEGVPPAVAASFNSLVPEIVVILFFSVVVFTLNHTT
                     GLNVPQLIELAIQTPLKAFVLSVPGILFLQFFSDFLWVFGMHGSSILAPIRQAPLLQS
                     IQENMDAFSVGKEIPNIITEPFTNAFGLIGGGGCILPLVIAILWASKRQEQRSIAKFG
                     LTTCLFNITEPIMFGLPVVMNPIYMIPCAIIPSINLVIAYAATSLGIISKTVAAAPWI
                     TPPVIQSFIATGGDIRAAVLTVILIILDVFLFLPFVLAANKAKLAEGGY"
     gene            29036..31336
                     /locus_tag="IXT46_001596"
     CDS             29036..31336
                     /locus_tag="IXT46_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 3 glycosyl hydrolase"
                     /protein_id="HAQ4947513.1"
                     /translation="MYDYPYQNPKLTIRQRVEDLLSRMNIAEKVGQVNQHLYGWECYE
                     KNGDKIELTEKLKEHVKWGGGLGALYGLFRSDPWSKTDYKNGIPAKESWKVANLVQEY
                     VLQHSRWKIPVLLVEECPHGHQGLDGISYPTNIGRGNTFNVALLEQSSRLMAKELAAK
                     GVHLALVSTLDLAKDPRWGRTEECFGEDPILSARFSEAVVRGFQGEIISEKVSFLDQT
                     VEEINKKKDQIGVVLKHCIAQGEALGGHNSGTVTIGRREFSDIYGPLLKSTRNAVGVM
                     AAYNDIDGIPCHINRALFEQTLRKEIGYQGIVMADGVALDRLSDVFTDKKTAAAYALA
                     AGIDLSLWDETYTKIAEAIDNQVVDEKLLDQAVRRVLSVKFLLGLFEQPFANDPKEYW
                     DHLMEESEHLNLETAKESITLLKNDGILPLDQQVKNIAVIGPNAHDVYHLLGDYSAPQ
                     TEDRLKKKIVQEIKTEFPQSKVSYAQGCEVRNQEDQEEKLLEAVTLAQNSDVIIAVLG
                     GSSARNFDMEFLRNGAVSSKGINMDSGENVDVASLSLGGYQEQLIEQLYQLGKPIITI
                     LVQGRPYDLMKIESFTNAIATAWFPGQEGGKAIAQMISGRNNPSGRLSLSYPRNSRQL
                     PVYYYQRAASKQENYYDLSGSPFYPFGHGLSYTTFEYSQMEVKTDIDKVIISIKVKNT
                     GSVSGKTSTLVYVRLIDGVVIQRTKLLKAFRKDELRSQEERLLVFELTSEDFSYMDID
                     DKRHYAKKAVIMVEQQEKEIKCNWQE"
     gene            31343..32314
                     /locus_tag="IXT46_001597"
     CDS             31343..32314
                     /locus_tag="IXT46_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4947514.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMEKISEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISNRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHAIDGLIVFLSEEEWSGFEMLTKMSIPVVALNCPGGPAGIDTIVVNDR
                     ESVAKVIAHHGGQGHKTIGFIAAAQTDYVARERLAGAKEAVQKDPSIHLEIFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            32336..33733
                     /locus_tag="IXT46_001598"
     CDS             32336..33733
                     /locus_tag="IXT46_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4947515.1"
                     /translation="MKRYQFPKNFWWGSAASGPQTEGRISGDGKGENIFDYWYKNEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HHYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFQLFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKAYHEMDQSGVI
                     GIILNLTPSYPRDESNPEDVKAARIADAFFNRSFLDPAVKGEFPSELIERIKELDLMP
                     EIHPDDLTIIKENTVDLLGINYYQPRRIKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEKGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDRNGFEA"
     gene            33889..34512
                     /locus_tag="IXT46_001599"
     CDS             33889..34512
                     /locus_tag="IXT46_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947516.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWEEYKLTANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLVVLLLTHDGDKVARLKNGKVVTAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     ASSQKNESTELSPSDSGSGQTITGNEENQASIITNESSEGQYQTYGQ"
BASE COUNT        11632 a         5654 c         7216 g        10165 t
ORIGIN      
        1 ttgggtgtaa aaggccagaa tttattggct gacgattcgt tttggcagat tgaagccttt
       61 taccttgccc aatgtgcata caatacaaca ctgatgcttt cgccagatag aattattttt
      121 ggcggtggtg taatgaaaca agaacacatg aagaaaaaag ttcaggataa atttgttgag
      181 cttataaatg gatatgttga aataccacca attgctagct acattgttac gcccgaatta
      241 ggtgatagtg ctggaataat cggcggattg gcattggcta gaaaggcgat aagaaataag
      301 taattttaat gaataaatgt ttcattggta ctcatgtcaa aagtatttaa ctgagtaatt
      361 aaatgatgtt tgataaagcg aaaatgaatt caaataaaaa aggatcgagc aaactggaac
      421 atttgtccga tcctttttca cattctattt atttcgttta ttcaaccaat cggtagagac
      481 atccattgcg ctcttgtcgc gtggctttga tccatataat tgaccattac gaaatcatgg
      541 atcatcgctt tgaatgcgaa cttgtgtcac atctactttt ttgaccagat tttgaccagt
      601 ctattttaca ttctaatgta cttatatgag ttaatttttt gagtaaatgg taagtttttc
      661 cttgtttgtt ttatcttaaa ctagtgtgta atttgaaaat ctatatggaa gggtctgtgg
      721 ggtaatactt aaataaaggc taggaacctg ataacatcaa ggttcctagc ctttttataa
      781 taaaatgaag cgaaaataat ttcttttaaa gagccgagat tatcagctat ataagagtga
      841 atttgatgca aaaaacagag ccgaaacagt cttggtgttc gtagctctgc ttatatgttt
      901 cgaatttaag acaaagagtt ggcaaaagat gttgataagg aagataagat aactgtgtta
      961 tataaactag gtaactaact gtaacaagct aattttaaga gattcttatt agaagacgtt
     1021 taggaatata actaagaaaa tgattataca ggtaattgtc atttcaataa tgttttctaa
     1081 ttttcgcgtc tttgttttaa gaaaaaggcc agaatcagtt ggaaaaaagt tcgtacgata
     1141 gtgaagaggg gcaaaatttc ctactaatat tcccactaac aagagataaa acggccaggt
     1201 tggtgtgatt cctctataaa aaaatgccca tgctaccgaa atcccataga ttaacaactg
     1261 aacaattttt acaatgaaaa aattgttctg ccattactca aagtctcttc ctccttgtat
     1321 cgtttatttg tttcatttta tcattatgat aggcgcttga acaatccatt ttgtatttta
     1381 ttgagtactc ttggataaac taccagcgat tatcatattt atttatgtta ctgtaagcca
     1441 tcatataaaa gtaaatgagc agatcataga aatataaaaa agaactaaaa ttgatctaaa
     1501 ttatgtgcag cttgactacg taccaatcta tattacttac tagattggtc gttaatctat
     1561 tcggatcgaa tgagcaaaat atttttgtga atgtccatcc ttgattatga ttccaaaaag
     1621 aatcattgga aggctgtggc gtaaatatta tactataagc cagaaatacc tatcattctg
     1681 aactttttta tttaggaact ttcatctcaa ggctttttca attaatttgt acccctgttt
     1741 tttggataag atcatgtgca ttgatttttt ctatctctac gttcatctcc tacttaatgc
     1801 ctatctggct cctgagggct tctttttaag gcgtcgtcat agtcttggct gaggatttct
     1861 tggtaatctg agggaatggc ttcccaagtg agcaggcgaa cgttcatgac gtgttttcct
     1921 ttgtgtttga ttacagcatg gtttttctct ttttctacct ctccagcgtg aaaagacagc
     1981 catgtaccat ggccaaagat atcattacat acccaacgtt cgatggaatt gtccacgtat
     2041 cctacaggga gtgtggtata gccgatttgt ggtttcaaaa aaggattgaa tcgatcgatc
     2101 gtttcatttt tgtattgata attgataaga aaaagataga ccaaacaaaa gacgagcaga
     2161 aagaaagata gtgtcttttt gagtgagaag ggttgttttg atgaataaga tttcttgtta
     2221 acaagaggtt catctggcaa tgttggttct attgattcgg tagctgattc aatagaagga
     2281 aaatcaatcg gcagacctaa agtatgatgt aaaagtgaca gcatttcaaa gtctggcatt
     2341 gtacgagaat tttcccaact agaaatcgtt ttatcggaaa caccaatttt ttcgcctaat
     2401 tctttttgcg taagcttaca atttctgcgg taagttcgta ttttttctcc ggtgttcatc
     2461 ttcttctcct ttcgattcta cagtatatag atttattcta catgacctat acacttgata
     2521 gatacgtttt tttgatgaaa aacggtatga ttttatcaaa gaatcattta agtaagggag
     2581 agtggtgata atcaaaaaaa agttcacagt tttactcaca atcatagtga ccggtatcat
     2641 gagtggtttt gccttggtta gtataaataa acaggtactc tatcggacaa atgaattttt
     2701 ccatcaaaca gatacttata ctccgattcg attgccacaa cattttattg ggcaagaaga
     2761 atatgagcag ctaatcatgg tatttgaaaa tgtctcatca gaaactgagc tttcttatat
     2821 gaaaaaaaca gtaaatgaat ccaatgaagt agatacatct tggaacttca agatacagcc
     2881 aaagcttgaa atgacattgt attatcaagg ggatgtcaaa tcttctcacg agaaggtacc
     2941 ctattctaat acctcctttc gcgtaacgtc cattgaagaa tcgatcaaaa taaaagattt
     3001 tgaaggtgaa tttttcttga tgacgagaga aaaagaagcc tatgaacggg tcatttcact
     3061 attcactgat cgattcaatc aagcatttca cactgattat gccactaata tttttgaaga
     3121 ctttgaaaat agctattcgt attcggttat ttcaaataca gacgtatata attatcgagt
     3181 gtatttaact attggattga ttcttttatt ccttttgtta tcatcctttt tcttattgat
     3241 gaataaagaa atcagtttat tgttgaataa tgacttttca ttacatcaag tattgtggtg
     3301 tttattgggg aaaaagaaaa tcattattac attcataatt gcaggaatca ttggtggttt
     3361 tatttttatg tattataagg agcaatttct ttatttgttc cagatgtacg ttttcttgtt
     3421 cagcggaata tatggtatct ctttgatttc tcttttatta gttgaaaaaa tcgcttcgtt
     3481 aagagaagcg ttcaactata tccaatacat tctttttaca tttggattgt tgttttctct
     3541 tcttttgacc gttgccaatg tcgaattagc aactatcgtt ttttcttctt cacagttagc
     3601 tgtttcccat gaaccaccaa aagaaatcgc tggtgaggac tatcatgtat tttatccagt
     3661 aaccatcggg aaaaaccacg tggattttat ttattccaat cgttttgcat cagcagcaga
     3721 tcaggaatta tatgaaactt tgaataaaaa cggaagtata ttagtcaatg tatcagatta
     3781 cttgaatgaa gaaaatgaac agtttggcag agggataaaa ataaatctga attatcttaa
     3841 gaaatttcct ttgattgatg tctctggaag gttgatccaa ataaccgaaa aagaaacgca
     3901 ccctgttata ttgatccctg aacgatatag acatacagat ttaaaaaatg acctggcgca
     3961 aataacagaa tattatcaag aaatcagtga aaaagaaccg aaatttctat ttataaaaaa
     4021 caatcaaccc atttatacat ttattccttc tatcccctgg atcgaacatt atccggttgt
     4081 tgaaatactg acattgaaaa acagtatgta tttggaaaga aatattctca gcggagaaat
     4141 ctatccaccg ttaaagatca agataggctc tttgtcgaaa gaaaggttat ttgagctgat
     4201 tgaagaaagt cagttacgtg ataacttgca gttatcattt ccgtatactc agactgaaga
     4261 gatagctgtc aaagtgttaa gcagatcatt tcattacttg atacagatat ttttactcac
     4321 tttcttttct ttcttcttgt tgagctatgt catgttatgc atatattttg tctacaattg
     4381 tcggaaaatc gctatctttc gttcaagtgg ttattcgctc tttgaaacgt ataaagattt
     4441 cttcatgatg aacctcatca aatggggaac gacaagtgta atcttccttt ttcttataga
     4501 aagagagcct aaatatcttt ttaatatttt tttctttagc ttcattgatt ttattctttc
     4561 agttgttttt attttgtcta cagaaaagaa aagtcagtta ttgctgatga atggaggtta
     4621 acaattggag ccgttgatag tgataaaagg tgcgaaaaaa atcattcgaa acaaaacgat
     4681 tcttcatttg gatcgtttca ctgcggatgc tggggatctt gtgactgttg ttggagaaag
     4741 tggagcaggt aaaagtacgt tattgaatat attaggattg aatgatcagt tcagttcagg
     4801 acaattctat ttgttcgatc aagagacgaa acaattaact gggagagaga agcgcttgat
     4861 aaaaagaaat accatatctt ttctttttca agattttggg ttgattgaat atgaaacaat
     4921 cgattttaat ttagatattg gattgaagtt ttcgaattta aatgtttcag ataagcgaac
     4981 agcaaagtat gaggcattga aaaaagtaaa tataaacaag aagctaagta cgcctatcta
     5041 cacattatct ggtggtgaga agcaaagaat cgcctgtgcg agagtcttat tgaagaatag
     5101 caaaatcatt ttagccgatg aaccgactgg gtcattggat aaaagaaata aggataaagt
     5161 agttgaaatc ttatcgcaac aagcttccca aggtacgtta gttatcgtag tcacgcatga
     5221 tccatatctg accaaaatag gaaacaagaa gatcatgctt taaaaatcaa aaaggaaagg
     5281 atgtcgtttt atgaaaaaag cagttattat ttgtgcacta gggataggtt ttgttggagg
     5341 aaacgctatg tcatctgaag tggaagcaaa ttcagttcac ggtgaaatct attacaaatc
     5401 tttaaagcca ggagagattc attttgatgc taaaggtaat attattaagt caaatttacc
     5461 agtagaccgg gaaatttcta gaacagcaat taatcatagc tctggaagat gggtttatta
     5521 tagtgataca acttgtacga gaaaaacagg tcattctaac cactatagtc gtgtctataa
     5581 tcgtcacggt gcaaaagcga aagttggaaa ctctattcga tcagcaaatg caacaaaagg
     5641 agtatgggcc tatgcaagtg cgacaggaaa tagaactgac acattctcat gttggtacaa
     5701 tccaaccggt tggtattaag tatccaaaag tttatataaa atagaaaaaa catataatga
     5761 aacagcgtta aaagttattt ttggtagttt taatatattc atttttagtt gtataaaaat
     5821 atatcataat aaaaacaaca aaaaaatgtc tggaaaatcg aacataaaag tgtctgattt
     5881 gaatatccca gcagcggaag aagaaaaaca aaatcgataa catttgttct aagaattagt
     5941 tacgttaaat acggaacgca agatagactt gaaaaacggt aacaaaagaa gtagtatatt
     6001 aaggtgtgat gtgctacttg acatttattc tgctgagcga actttctgga ttgtgtagcc
     6061 ttatatctat tcaggacgta tcgagcagat tagtaaaggt gttcttgatg attttcatct
     6121 tgaacacctt tgtttttagc aattcgcaaa aaacgaaaag taggagaatt gataaatgaa
     6181 aaaaagattt ttagcacttg ccatcgtact aggcactggc ttattgtcag gctgtacgaa
     6241 tgccggtgaa aaaacagccg ttagttataa aggcggtaca atcagcgaac aagaagtaat
     6301 ggatagcttg aaaaaaatgc aaggagcaga ttccgctgtg caacagttga tcgtttatca
     6361 agtatttgaa gataaatatg gagatgacgt atcaaccaaa gaaatcgatt ctcaatatga
     6421 tcaaacaaag aaacaattgg gtgattcatt tgattcacaa ttgaaatctg caggttacac
     6481 agaacaaaca ttcaaagaca gtatcaaaca aagtctagcc tttcaagaag gtctaaagaa
     6541 acatatcaaa ttgaccgatg aagatttaaa aacggcttgg gaatctttcc atccagaagt
     6601 ggaagctcaa attatccaag tagcaagtga agatgatgca aaagatgtga agaaagctgc
     6661 tgataaggga gacgatttct ctaaattagc caaagacaag tcaactgata ctacgacaaa
     6721 agaagatggc ggaaaagtga aatttgattc cactactaca acggttccgg cagaagtcaa
     6781 agaagcagcc tttaagttga aagatggtca agtttctgat gtgatcactt ctaccaatgc
     6841 ttcaacttat actacggaat attatgtggt taaaatggtg aaaaaccaaa acaaaggcaa
     6901 cgacatggat aaatacaaaa aagaattgaa agaaattgca acagacacaa aattaagtga
     6961 cagtaccttc cagaataaag taattggcga agtattgaaa gacgctaatg taaaaatcaa
     7021 agacaaagac tttgaaaatg ttttgagtac attcacttca gattctagta cagcaagtag
     7081 taaataagcg gtataaataa aaaatatgaa ctatttaaat caataaaact gttcatctaa
     7141 atctttttat tagaactaaa tcaacagtag tttaattact acttgattta gttcttttta
     7201 ttttaaaaat tttttttact tagaatccag cgaccctaga tatttttctg tataatctta
     7261 aataaagaaa acaatatcaa aaaatgcacg tagaagtaga taaatggagt ggttttgcaa
     7321 atttctttta tttctagaag ttattcacgt atacggattt gtttttctca caaataaaaa
     7381 ggcaggaagt acaatggatc atttgtatat aaaatatatt catcaatttt ccgttttggt
     7441 gttaggcaca ctaattatag cggggattgt cgcatttatt attcaaggcc gtgacatatt
     7501 aacagtacat caagagtttt tcagttatgc atttggtatt cctctgatcg ctataaggtc
     7561 tgataacaaa aagtggaaga aacgctatta cattctcttg ctatttttgt gtttttatct
     7621 gccacctaag atttttactt tattaggtat acaatgccta tcattttctt ttatttccta
     7681 tatcattgtt ttaattttcc tcagtttcat agtatggatg ttttatcttg tcaaaaaata
     7741 aatgaatgtt tcatgaacag tacttcatca cagcctaatt tttttcttta tgctatcgtt
     7801 atattaaaga aatcaatcag aagggaaaga aagtgatgaa aaaagtttta ttagtggtaa
     7861 accccagttc aggcggtgaa caagcaaagg aatttgagca attagcgata gcaaaattgg
     7921 aatcggtgtt tgatgaagtg gtcgtcttgc atacaaaaaa agcaggggat gcaaaaaact
     7981 ttactcgcga agcggctacg gaagggtatc atagtgtgtt tgtcatgggc ggagatggaa
     8041 cagtcaacga aggaatcagt ggaatcgctg aacaagaaca tcggccaaat ttcggatttt
     8101 tcccattggg tacggtgaat gacttggctc gagcattagg gataccgcta gaacctgagg
     8161 aagcgatcaa tcatttttcg attgaatcag tcaagccatt ggatattgga aaaataaatg
     8221 acgactattt tatgaatgtc gtcgcaattg gctctatccc tgaatcaatc aatgatgtag
     8281 atgcggagaa gaagacgaaa tttggaaaac tagcttattt catgtcagga atcaaacagt
     8341 tagcttccac acaatcctac tcgtttcacg tagaagttga tggaaagaag gaagaaattg
     8401 agagcagtac cttgctgata ggactaacta actcagtcgg cggttttgaa acattacttc
     8461 caaatgcaaa agtggatgat ggtaagctcc atttggttta tttaaaagat tcttctttga
     8521 tcgatacgct taaaacattg ccagacctat taaaaggagt agatgaatct acgaaaaatc
     8581 tagcctacct tacttgtgag caattagttg tgtcattagc tgatgaggaa gaattgacga
     8641 cgaatgttga tggagatgaa ggggataaat tacctgtgac aatcaaagta ttgccctcac
     8701 atttacaggt ttattgttaa aatggaggtt gtgaccgagg agttggcggg agaacaccgc
     8761 ttgttcggga taagggactg tgacaagact tttgtcacag cctttttttt gtacaaaaaa
     8821 gaaatttaca cctaatagaa aaatttttcc ataaaaatac atattttaaa tatgaaagta
     8881 caattggaaa tagattaaaa cgataaaata aaattgtcaa aacgtcagag aggatggtgg
     8941 agaatgaatc aatgtgtaaa aaagctgatt gcgtcgattt tgtttgtctt ccctctcttg
     9001 atggtgacat ccgtttttgc cgatgtagag aaaacaaacg aatcaacgca atcagagaat
     9061 caaagttttg acaagactac tttttcagaa gaatcgatta cttctgaaac tacagaatct
     9121 caaagtgagg cttctactaa taaaaggcaa gaagaaaata agacaagtga gacctcagaa
     9181 gtagctgaac aaacgtctga tagcagtgaa gcggcactgg caagagctgt ttcagcggat
     9241 gggtacagcg aagctgccac aacagaagaa ctggcgcagc ttctcgcaga cgaatcagta
     9301 actaagatcc gactgattca gcctttgact ttagacaggg aattagagat caaacgagat
     9361 atcgttattg attttggtgg attcgctcac aatttcggca cacaccatat ttatatcaat
     9421 gagatacctc agtcgatcga gttccagaat tttaaaggaa cagctgcaca tccaggtgga
     9481 ttgacaccaa atatcgatgg aaatgccatt atcattgctt atatgaccga tttttgggga
     9541 agcagatatc attttacggg agaaataaaa tttaccggga cacttgattt gtatgatggg
     9601 tccaaattag gactgattta cgctcctcgt gcaactgtca cattagatgg tgtttccggt
     9661 gtgttggatg tccaaccagt gaaggaagga ctgaatgccg ctccgggtaa agcctatttt
     9721 tgtagaagct atcaattgaa tgtgatcaat ggtagtcaac tttatggacc gtatctaggg
     9781 aaattctacg gttttctaga ttcaggagat gagactggta gtggaaaaac agcgccagga
     9841 atccatatct taagcggttc aaaggtctct cttgattatg atcgggcaga tggcgttagc
     9901 gatgaaggag aggcagtcga tacgctacct ggtaatgtca tgtttgaagt cagtggttcg
     9961 ggaagcgaat tttcggtaaa tacaaagatc aatattacca atgacaacaa tcgcggaatc
    10021 atccaaatga gaggttcagg atcgaaagtc actgtatcga atggtgggaa aatcaccatc
    10081 aatacagcaa ctacgggcgg atttcgcttg caaggagatt ctagtcaaat ccatgtatca
    10141 agtggtggac aaatctcggt caaaatggct ggagatgacg atcaacccgg gaacaatggg
    10201 atgcgttttg taggaaaagg cctttctttg atcgtagaag gagccggatc agttatcgac
    10261 atcgataagc agagtgggcg ttccagcgca gttcgttttg agaatggtac gcaaaagctg
    10321 acagtaacca atggaggctc attgagggta agaaatacag gtgatggcaa atcttacgtg
    10381 aacagactca atcaaggaaa tcaagcgatc caattttatg acgcttctgg ttttctagaa
    10441 agtccaggtt cagctgattt tacagtcact ggagaaaaat caaatatcga tatacgcgca
    10501 gattccggag caactgtaga tacaactgga gatattgatt taaattttac ggcaggtgaa
    10561 aaaacttatt tagtcatggt cgggaaaaca ggggaagata agaccggcat catcagtggg
    10621 gatgtgttga atgtggactt agaatctcct acctattttg atttccaaaa caaacggatt
    10681 ggaagcgaga ccaatggcat aggcggctgg gtattccaag gaaatggaga ttcttcttta
    10741 aagatcgccc attcagaaat cgctttatgg cgaaaaacag gcgcaacatt cgataacttt
    10801 gaaaaagacc cggattattt ttctgatatg acagacttat cgatcaatgg gaccgactta
    10861 ggcaatttcg tatcaagccc tagtgcaggt ttaacaaatg aatttgctca gacaggtgcc
    10921 ggaatgaaaa attataatcg aatcagtgcc aataatcagc tcccgatgat tgaatcctta
    10981 agagtgccaa cgaatgcaga taaaaaaatc tatgggcatg tcgttgttcc cgaaggtgtc
    11041 gaggcaaagc caagagatgc ttggacaggc gaagtagaag tgactttacg tattacttac
    11101 gcagatacga cgaaatcatc tgtagaaatt actgctctca cgcaaggaca aacagatgaa
    11161 aatgaagggg caggatataa cccatgggga gaaggcgaac aaggcggctt gttcgaagtt
    11221 caagtaccca atgatgagag attaaaaacg gaggatcaag tgcaagttgt tgctgctaaa
    11281 aaagtaagag gtggccaaga agtgacagaa ctggactctg ccaaaacgac agtcgatgtg
    11341 attcctcctg aacctgctaa tttaagtacc acattgatca atgcagcttc tcgcacgatc
    11401 acaggtacag gtgaagcagg agccttggtt tcattgaaaa aaaatcaagc tgttttgtca
    11461 gaaacaacta ttgatgatac aggggaattt gttctttcta tcccagaaaa tcaacttttt
    11521 gcaggagatg tattagaaat tgtattaaac gaccaagcag gagaagctac tgctaagggt
    11581 gtgcagaaca agccaagtac caacgatgaa attgggaatc acaatccaag tgatacgcca
    11641 gttgtttatc atgatgcccc gccttttgca cctgctacga agatcgtagt agaaggtggt
    11701 ctctcatttc ttgccccttc caaactcgat tttggtcaga tcaaagcaac tggtttgaca
    11761 caagaagcat ttggccaaat ggatatacag gaaaaattat ggatttatga tcagcgagaa
    11821 acgaaaaatc cgtggatctt aacgataaaa ttatctcagc ctttcacaaa tgatgcagga
    11881 ttttctatgc aggatgtcct atatttcaag aaaggagagg agtatcaatt agtgaatgaa
    11941 gaagaactgg aaattgtcag aggacaaaat tcaacgaatg tgcaagcaga ttattcagaa
    12001 tatttaaata acggtcgggc gtttaaactt gtcttaacca aagaaaatca gatagctggt
    12061 aattactcag cagagataac atagacatta gcagatgcgc cgacagaata aagatcaagg
    12121 aggatgattg atgaatcgaa tatggaataa aagtcatcga aacaactgct ctttacttat
    12181 gatccttctc cttggattca tcctttggca gacacctgtc catgcctccg aattcaattt
    12241 tgcggtagat tttgaattac cggctaatca gattgataag aacaaaacat atataaatgt
    12301 aaggatggag cctgggaaaa cacaggaaat cccctacacg gtctttaacc gaacagataa
    12361 atcagtaaca gttgagacat tgatccactc cgctacgacg aattcaaacg gtgtgatcga
    12421 atatggagaa tcaaaaagta aatttgatga aacattaagt tatgatatga aaaacttagc
    12481 aaaaacagtg ggagaaataa ctgttcctcc tcaaagtgcg gtcactgaga cactttcact
    12541 gaaagcgcca gaaaaagagc tggctggtgt ggtcgcagga gggatcacgt ttcaagaaaa
    12601 aaaagagaac gtttctaaca aaagtacagt tggtgtcgtc aatcagtttt ctcaagtgaa
    12661 agcaatcttg atttgaaata gcgaaaaaga gtcttcccca gatttgaaat taaaaaaagc
    12721 ttatgcggat caaagcgatg gaagaaatgt gattaaggcg aatcttcaaa atccaaatgc
    12781 ttcttatatg ttcggcttga ctacatcggt tgaaatctac aaaaaagaaa caaaagagcc
    12841 ttacctttca ataaaaaaag aaaaaataga tgtagcaccc aatacaaatt ttgatttact
    12901 tgtcccatta gaaggaaaaa aattagctcc gggacattat caagcggttg tgaagggtgc
    12961 ttggaaagaa aaacgctgga atctccatac cgattttgaa ataactgatg atgcagcgga
    13021 ccaattgaat gaaaaggata ttgatttaaa aaatcagcca gaaacatttg actggcgatg
    13081 gctgatactt gttggagtca ttcttattgg cttatttgct ggattattta ttttaaaaga
    13141 aagaaggaaa aagaaatgaa aaaaacaatt gcattaagta ccgttctagc tggaagtcta
    13201 ttattatgta cacaaagtgt ttttgctgag aataagagct cagccactac agaaggaacg
    13261 atttctgtga ccaaaccaga tgctgcaaat cctgaagacg ttgttccagt tcctcctgtt
    13321 gatccaaatg atcctgatac tccttttaca cctgacgaac caaatcaggg aacatccgga
    13381 ttactgacga ttgaccaagc tccagatctt gattttggaa caatcaagtt aggtacagca
    13441 aaaacagtat atgctgcatt acaaagcgga acggacagta ctggagcaca aacacaagta
    13501 cagaatttcg tacaagtaac ggataaaagc ggaaattatg ccggttggaa attatcagtc
    13561 aaacgaacag aatttattgg tacaacatct gatacgaata aactaactgg ttcaaaggtg
    13621 aaattcaaaa acgccgtgat tcgaaatagc gcaactaata gcagtggaat gccatctacc
    13681 gtttctggaa ctggcgctga aggaatcgaa atcccagcag atcaggcagt agatctagta
    13741 actgcaggag caaatgaagg gattggcaca tggatttatt cattaggaga gaatgtggaa
    13801 caagggagac aatcagtgga attatttgtt cctgtatcca attatgctgt agacaactac
    13861 gtttcaacat tcacatggtc gttaacagat gctcctacag aagaggaagc gtaaaatcat
    13921 atcaacgact tcagggagtg gagccgattc aaggcccact ccctgaaatc tgctatgctt
    13981 acgtctcagc tcttattcat caactcgaag cagttttttg gaagtcatgg aaacgttcct
    14041 ttgtcttttc aaagatcttt cgaccaacga gtaaggagtc accgttgaaa aattctaaca
    14101 cataatgagc agaatcaatt ttctgcaatt gcgataagtt gatacagtaa gattttaaaa
    14161 gtaaaaagta agcatacttt tctaactctg tcttcaattg ttttaaagaa gtattcacta
    14221 atttatcttc tgtagttgtt ttgaccataa cttggttttt caaacctttg atactttcaa
    14281 tatataaaat ttcccgagga tacaggacga gacttccacc tttttgatca ataaagattt
    14341 tatcgacatt tacgatctgc tgttctttcc aattgatctg ttctagcact tgacgaattt
    14401 gttcagataa attcctgtct tttctgatat atccaatcgg aaggattttc cgattgatga
    14461 tctctactgc aaaattcgta taagcggtga aaaaaacaat attactatgt gcattttttt
    14521 tacgtatttg ttcggcgaca tcaatacctg tgagtgattg cttcaagtcg atatcgataa
    14581 agaaaacatc gtgattatca atagtgccca actggatcaa ctgattgatt tgagagatag
    14641 aagtgagctg cacgatattc tcgatatgat gattgaccaa ttctctgatg atccattcgc
    14701 tgtgaaactg gttatcttct atgataaaat actttttcat atgcaggctc ctattaaaaa
    14761 aatatgtgta cattttgaaa caaaacaatg gaggaataag atggtcgcaa cagtgacact
    14821 ttatttgacc tttactttga ttttagattt aggtatctat ttattctttt cgaaacaact
    14881 gctagtaaaa aacagctttg gttgtatagc tttgatggtg gtgacacttt tacttcctat
    14941 ccctaaagtg agctttcctt acctaattgg cttattattg atgtttcttt tttattttac
    15001 tacgaaaaac ctgtttatca gctgtttgat cagtaatctt ttttttgcta tcactggact
    15061 cagctttttt ctggtttttg atctgatgga ttatttagga aagagacatc ttggaacagc
    15121 aagttttttt gcactactta tcgcatttat tttctatcta ttagtaaaaa gtatagacaa
    15181 acagacgaga tttctcaact tgctttttac ttatccaact gaacactatt ttggaggtat
    15241 ttgtatttta ttaagctggg gcgtgattta cttggtattg ggaagtgttc acttccgctc
    15301 atctaattat ctgcttctat ctcttttgtc gatagtcatc agtttttttt ctttgttttt
    15361 ttccattatg ttgatcagtt tccaagtaaa agaaagacaa catcaggaat cgcttcaact
    15421 gtatcaaata aatgaagaat attaccatca tctagaggaa ttcaaacatg attataaaag
    15481 tctactgttt tcattaaaaa ttactcttca ggaaaataaa aaagaaacgt tggaattttt
    15541 agaaatatta gaagatcatt ctgcagctat ttttgaaaaa ccgcaaatac aacagctaac
    15601 aaatattgta tccccagctg tcaggggtgt ctttttaaaa tttctagaaa aagcagaatc
    15661 ggagaaaatc ccgatccaag tagttattcc tgtcgaagtg aaaacaatcc cgattgatct
    15721 ggttgttttt attcgctgtt tatctatttt tatttctaac gcattcgatc atcgtgtagc
    15781 cgatcagagt ccgattacga tcaatctgct ggaagaaaaa gagggatcac gttttagtat
    15841 agcgaacaag gcaaatccaa cgaatttgac gctatcggag atggtcaaaa gaggaaaaac
    15901 ctctaaaaaa aatggcgggt taggtctata cagtgcgaaa aaaatgttgg atgtttacga
    15961 aaatgcagaa ctaaaaatcg aattttcaaa acagaatcac tatttttttg tagaaatgta
    16021 tctggcatct agaaagagca aatcagccta ctgacttact gtcaaaggat aagtttgagg
    16081 aaagtctaca cggagataga gacaacaaca cagcatattc aaaagaaaca gaagcgtgat
    16141 gaccgttgtc acccttctgt ttcttttgct atgtagttaa acaaagtagt tgacacttcc
    16201 gctacttagt attagtacga aagtatactt catgatacta agtagataag aagtgaaaag
    16261 cggaacccac gatcgtcaaa atgctaactg ctttgcttac accagataaa gggaagagca
    16321 atatcgctta ttttaggcgt ggagaagcaa gcaaatccct acgatcacaa aaaaatgctg
    16381 acccagcagt taagagagtt agaacaagat gaaagtatcc atcgaaaagc ctataaccaa
    16441 gtcccgccta aagtagagta ctcgctcacc gaagaaggaa aatcattaag agagattcta
    16501 gtagcgttgt ctgtttggga agaagaacgt atcgaaaaac aaaaagcctc aagggaagaa
    16561 gacacgctac tgcatacaca tggtggctac ctaaattatt gattttctat gacatttatt
    16621 ttaaataaaa gaaaacagga gtttttttaa aagcatcatc tattttttat gtaaaaaaat
    16681 ggtatgatta atcaagtaag aagtgattgg aagaaggcaa gcaaatgaat agtatggaaa
    16741 aagtcaacca gtttagagat gaacgtaatt ggcgacaatt tcataacgaa aaagatttgg
    16801 ctatctctat ttctttggaa gcatctgaat tgttagaact ttttcaatgg aaaacgccgg
    16861 aagaagtaaa agaaacacaa ttagaacgaa tcaaagaaga actggcagat gtattgatct
    16921 attcatacat gatggcagac aaccttcacc tggatctaga tgagatcatt gaagaaaaat
    16981 tgatcaaaaa taatttgaaa tatcctgtag aaaaaagcgc aggtgtacga aaaaaataca
    17041 cagagttgta gaaatgtgtc attcggctgt tggaaagagc aaaagaaaaa cagtaaaatg
    17101 agtctggagg gagagaaaat gaaaaaaaaa ggaaaagcaa aaagatggct agtcaatatc
    17161 ctcttgttcc tcttgttatt agtaggacta gctttgattt tcaatgaaca gatcaaggat
    17221 tattttgtca gagagacagg agataaatat gctatagcga atgtaacaaa agaagatctg
    17281 aaaaagaata acgataaaga tgtcagtttt gactttgatg cggtagaacc aatgacgaca
    17341 gaaggggtca tgaggtcgca aatgagagga acagatctac cagtgattgc tagtatcgca
    17401 gtcccttcag tttcaatcaa tttaccggtt ttcaaaggct tggataatac gtcactactt
    17461 tacggagcag gaacattatc tccagatcaa gaaatgggaa aaggaaatta tgccttagca
    17521 agccatcgtg caacgaaccc tgaattgctg tttacaccgc tagaaaattt agagatgggt
    17581 gccaagatct atttgacaga tttagaaaat gtgtatacat acaaaacatt ttttaaagaa
    17641 aaagttgctc ctacagatac ccaattactg aatgaagtcg agggaaaaga aattgtcaca
    17701 ctaattactt gtggcgacat ggacgccgtc acgcgactag ttgtacaagg agaactggaa
    17761 agtgttacat cgataaaaga tgcgacagat gatatgagat ctgctttcaa tctagagaca
    17821 aaaacatttt aggatactgg gacataagtc gttacagatt aaaaacagcc aaaggatatg
    17881 aatcgataag gaaaaaccaa tttgctgaaa aaaagagaaa cgcaaagagg tgcatctctg
    17941 atttggttgt tttctagata gacttgtgtt ccagtttttt tattttttat atgaaaaggc
    18001 ttgcataaat aaaaattcga tggtatgatg attttgaata agaaatggat tgttactgta
    18061 cggcaggcaa aaccagaatt cagctaagaa acagtaggcg aattctaggt ttttttattt
    18121 ttcttgagag ggcgaagcaa aatgaaaatt gataaaattt tgaataacaa tgtcgtcatt
    18181 tcgaaaaatg gattcgggga agaagtcgtt tgtatgggaa aaggactagc ttttcaaaaa
    18241 aagattgggg acgagatttc gccagaagcg gtccaaaaag aatttgtttt aagagattct
    18301 tttgctaaaa accaattcca gcagctgatg gctgatattc cggcagagga gatcgaatgg
    18361 gtcaaacaag tagtcgaact ggctgaagat aaactaaaag ttgaattttc gcctaatatt
    18421 tatctgacat tgaccgatca tcttcattat gcgatcacac gagcaaaaga aaatatccaa
    18481 ctgcctaatc cattattatt tgaaacaaaa aaattttatc cgaaagaata tcaagcagcg
    18541 aaagaggctc ttttgttcgt gaaacaaaag acgggtgtgg aactttctga ggatgaagcc
    18601 ggttttattg cctttcattt tgtgaatagc caacaaggaa acgaagacat gcaagtgacg
    18661 atgaccgcta ccacaatggt aagagatata ctgagtatca tcagtaaatt cttcggcatc
    18721 gtgttcgatg aagaatcttt gaattatcag cgtatcatta ctcatctgca gttttttgcc
    18781 cagcgttatc tcaaagggga aggatctgac gagcaagatg aatttctcta cgcattagtt
    18841 caaggaaagt atccaaaagc gtttcattgt gtcgaacgga tcaatgagta tcttcgacaa
    18901 acgcaaaaac aggaaatggg gatcgcagag cagatttatt taacgattca tattcaaaga
    18961 gtagtaagtg agaaaaaaag catccaatca taaggattgt tactgtatgg caggcaaaac
    19021 ctggattgaa aaaataggtt cacgaatgtt tgtgactgtt tttttcaatc tgggttttta
    19081 ttttttaaat aaaaaagaaa gaaggaaaaa acaatggata atcaagcagt tggtcgtcgt
    19141 gtatgggaag cggtaggagg acaaaagaat gtcaaaagtt tagtacattg tgctacgcgg
    19201 ttgcgattca gattaaaaga tgaatcttta gcagatacgc aaaagttaaa agaagacccg
    19261 gacgtgatcc aagtcgtaca aagtggcggt cagtatcaag tagtgattgg cagtaatgta
    19321 gcagatgttt atcaatcgat cgtggatgag gaaggtcttg cagtttcgga ggatggaaaa
    19381 gaagagtcca aaaatatttt gaatcgtctg atcgatatta tctctagtat atttacacct
    19441 tttctagggg cgatggcagc cgccggggta ttgaaaggat tcttatcatt ggcaacggtg
    19501 atgggctggc tgacagctga tagcggtact tatcaaatat tgtttgctgc agcagatggt
    19561 gtctttacct tcttacctgt catgcttgct tttacagcag ctaaaaagtt caaagccaac
    19621 cagtttttag cagtagcaat tgctatggca cttgtgtatc cagctatcac agcagttgct
    19681 ggtgcgggag aagctatcag tttctttggg atcccagtga ttctttcacc atctggttat
    19741 acttcttctg tcataccaat cattctagcc gtatgggttc aaagtaaatt agagccattc
    19801 gtaaaaaaag tgattccgca atttctgcaa atgattttag ttccgcttgt cgttttagta
    19861 gtgatggttc cattaacatt tcttgcttta ggaccaatcg ggacggttgc cggtaatgct
    19921 ttaggcggtc tcttcaactc gatttatgga tttagtccaa tcgtagcagg tctaatcatg
    19981 ggaagtttat ggcaagtatt cgtgatgttc ggcatgcatt ggggattcgt accgatcatg
    20041 tttttgaata tcgaacaata tgggtttgat gtattgatgc caatgcttct tccagccatc
    20101 ttggcacaag gtggggctgc tttagctgta gcattgcgaa caaaagatac gaaacttcga
    20161 gcattaggga tttcttctac agtgacttcg ttatttggaa tcactgaacc aactgtgtat
    20221 ggtgtgacat tacctttgaa gaaaccattc attgccgctt gtatttctgg aggtattggt
    20281 ggagctatta tcggattttc cggagtaaaa gctttctcca gcagtttggt cagcttattg
    20341 acgattccga ctttcattaa tacggtggat ggtgtagagt caaatgtgac agtagcagta
    20401 atagctacag gaattgcttt tgttcttgca ttcgtaggta cattgatttt aggatttgac
    20461 gaacaaacac aagacaatca attagaaaac aaacatgcga atgcaggaga accgattact
    20521 tcagcacggc ataccttaaa aagtccttta acgggtaaag tactgccatt gagtgaagta
    20581 ccagaccaag ttttttcttc tggcgtgatg ggaaaaggta tcgctattga tccagaagta
    20641 ggagaactag ttgcacctgc agacggagag atcacgacta tttttccaac tggacatgct
    20701 gtagggatca caacgactga cggagcggag attttgattc atatcgggat ggatacagta
    20761 gaattaaatg ggaatggctt tgagatctta gtcaaacaag gggatctcgt caaagcagga
    20821 gatttattga ttcgttttga catcgaagca attagagcag ctggctatag cgtaatcact
    20881 ccagttgtca ttacgaatac tgatgcattt gccgatatac ttgaattaga ccaaaaagag
    20941 attattgcaa acgaagatgt tctggcaatt gtaaaataag gaggaaatca ggatgcaatc
    21001 acgtttttca gaaaaatttt tatggggtgg agcaactgct gccaatcaat tagaaggggc
    21061 ttatgatcga gacggaaaag ggctatccgt tgcagatgct atgcctggag gtaagcagcg
    21121 ctttgcgatt atcggcagtg aagaatttga ctggacgatt gatcaagaaa aatatattta
    21181 cccgaatcat cgaggaattg atcattacga tcgtttcaaa gaagatcttg ccttgtttgc
    21241 ggaaatggga ttcaaatgtt atcgtttttc gattgcctgg acacgaattt ttccaaatgg
    21301 agacgaaggt actcctaacg aagcgggatt agaattttat gatcagctga ttgatgagtg
    21361 cttaaaatat gatattgaac ctgtgatcac gatttctcat tacgaaatgc ctcttcattt
    21421 ggcaaaagaa tacggtggct ggaaaaatcg aaaactgatc gacttctatg aacgatttgc
    21481 tcagacagta ttagagagat acagcagtaa agtcaaatat tggatgactt tcaatgaaat
    21541 caattcggcc tttcactttc cagctttaag tcaaggatta gtaaaaagca atggagcagg
    21601 agagtaccaa aatattttcc aagcatggca taatcaattc gttgcaagta gcaaagccgt
    21661 aaaaatcggc cacgaattgc gttcggatat ccaaatcggc tgcatgatta tctatgcaac
    21721 aacttacagc atcgatgcca atccagtcaa tcaggcagca acaatgatcc aaaaccaaga
    21781 attcaatttt ttctgcacgg atgtccaagt acgtggagaa taccctgcat acacagcgcg
    21841 tacccataaa aaatatggag tcgatccgga aaaattagag caaacggaaa aagacttcca
    21901 gttgctaaaa gaatatccag tggactacat cggatttagt tattatatgt ctacggcaat
    21961 caatgagact gatccacaag cagcaacttc agaagggaac ttgctgggag gagtaaaaaa
    22021 tccgtttctt gaggcaagtg aatggggctg gcagatcgat ccagaagggc tgagaatcgc
    22081 attgaatgaa ttatacaatc gttaccagaa accattattc attgttgaaa acggtcttgg
    22141 agccattgat catatggaag aggatggcac gattattgat gattatcgga tcgattattt
    22201 acgtcgtcat atcgaagcga tggctaatgc agtagcagac ggtgtagatt tgatgggcta
    22261 tacgccttgg ggatgtatgg atcttgtcag tgcatcaaca ggagaaatga gtaaacgtta
    22321 cggctttatc tatgtggatc tagacgatga aggaaatggg acactgaatc gatcaaagaa
    22381 aaaatctttt gattggtata aagaagtaat tgcctcaaat ggcgtaaact tgtaattaaa
    22441 gcagctgaat gaaaaagaac acacttctca catgtgattt gtgttctttt tttatttttt
    22501 atgtgctatt cttttagtaa tagtaaagca aagggtgacg ttatgaaaag gacacgtgta
    22561 ctatacttgg aagtcgcaga taaaattaaa gaagatattt tctcaggaaa atatccagtc
    22621 ggttcgatgt taccgacaga aagtgaatta gaagaactgt ttcaagtcag caaaatcact
    22681 gtccgaaagg caatcgaact gctggcatca gatgaatatg tcgcaaagaa aagtggtcgt
    22741 gggacgacgg ttctaagcaa tcgtccttac aatcgattat ccaaagcggc aagctttacg
    22801 caaatcttgg agaactcccg atatgaagtc cggaaagaaa cgctggattt gcaattggtc
    22861 catataaaga aggaagatcc tttgttttcc tttttcggtg agcaagctgt ttgttttaag
    22921 cgcttatatt atttgaacaa tcagccttat atttattttg ttcattatct tccacaagaa
    22981 atgatgcaat tcagcagaga agaatttggc aaagaatctt tgtatcgttt gctgacgaaa
    23041 aaaggatata ctattgactc attttctgat gatttctcgg cagtattttt aacagaagaa
    23101 gaacaagaaa ttctgaaaac agacgcacag atcggcatca aacggatacg gaaatcgtct
    23161 acgcaaattg gggaaatgat tgaatattcg gaggcggtct accatacgga gctgcatcct
    23221 taccatattg attatgaaac ataaataaaa aaagaggttg tgaaaaagct gccctgcatc
    23281 aagtaataag aacagccaaa caaaaatagc ttctcatatt agcttctcat atttttcgtt
    23341 tggttaggct tattaccgca gatacccggc tgtttctgga ttaccattta ttctggataa
    23401 gggggtgtgg cacgattttc agaaggaatc tatgaaccaa tcactgtatt gattttagct
    23461 tcgatggtaa ccccattcgg cttgacgatc gcttatttct tagggaaaat cattcgtaaa
    23521 aatatattca atcgtcaaga aatcgataca ttgaagaccg cttttcctat ggggatctgt
    23581 cagatcacag agggatgtat ccctatcgta ttgaacgact tggcacgcaa tgtcatagca
    23641 acgggagtcg gtggggcagt cggcggtgga ttgagcatgt tttggggcgc agatagccgt
    23701 attccggcat cgggaatgtt tgcagtcgct acgatgacca gaccatgggc attcattggt
    23761 gcattgttag ctggttcttt tgctacggga ataactattt tattattgaa aaaaccagtt
    23821 gacccaaatg cagaagtcat ccaagaagaa aaagaggaag aagagatatc ttgggatgac
    23881 ttgacaatca gttaggagga acagaatgga ttacaagaaa agagtacaac aaatgttcct
    23941 agattcagga gtagtattga aagaaacaga attagaaaga atcgaatata cagattttgg
    24001 attaggagca atcgagactg aaggattgaa tttatttgtt tatgaaaata atgagcgata
    24061 ctgtgggaaa gaactggtat tattgcctta tcaaacttgt ccagagcatc ggcacccacc
    24121 tcgagatgag aatgaaggaa aaaaggaaac ctttcgttgt cgaaaaggct tagtatatct
    24181 ttatgtcgaa ggaaaagaaa caaaaaaact ttcctgtatt attccaaagg ggcaagaacg
    24241 ttactatacg gcaaaaaaag aaatcatact tcacgctgga gatcagtaca cgatcgaaca
    24301 aaatattaaa cactggttcc aggcaggtgc aacaggcgcg gttatcaccg aattttcttc
    24361 cagcagtgat gatccaagtg atagttttac gaatccagct atttatcgtt aatacaaagg
    24421 tttgggaaca agctgatgaa ccaaaatgat caaatttcga ttatttggtt cgtcggcttt
    24481 tttatttaga gaaacatcag gcgttggtga aacataacac gagaataaaa tggatttttc
    24541 attaatagga gaaacaagtg tgtgactatt taaataatgc gtgttattga catgcaggac
    24601 gaaatcccaa tttcttctat aagtaagtcg tttcaatttt atatttacta gttatttatt
    24661 tttttggtta ctgtaaaata gctgaaaaat tatttttttg caaatactat atatagtggt
    24721 gtttgatcta tataccacta aaaaactaca aaatctagtc ttttatttta aaaaaacacg
    24781 tgtagaatga agatagactt ttgagttagg gagtgttttt ttatgaaact tactgttttt
    24841 tgcggttccc gttttggcaa taaagaaagt tacaaattta ttgcgcaaac gttaggaaaa
    24901 tatatggcac aagaagaaat cgaactggtt tacggtggtt catactccgg gattatggga
    24961 gtgattagta aaacagtact ggaaaataac ggaaaagtca caggtatcta tccaaatggc
    25021 ctttttgaaa ctgagctgcc tgggaaagat gttactacat ttattcctac agagacaatt
    25081 gatgaaagaa aggtattatt atttgaaaaa ggagatgctg tcctcgtttt ccctggaggt
    25141 ctaggtacat tggaggaatt ttcgcaactt ctttcttgga tagcgatcgg cctgacacct
    25201 gataagccaa tcggaatatt gaatattggc ggttattaca gcggcttgca acaattatta
    25261 gaaacttttg caaaagagga ttttatggat aaaaaatggt tggatcaagt gatcttttcc
    25321 aacaatccat tggaactggt caatgaatta cgagcagtat ctattaaaaa tcagttatta
    25381 ttgaaggagg caaaataatg agtcaaatat atttagcagg accatttttt tcagaggagc
    25441 aaatcgatcg agtaagtcgt atcgaaaaag cgttggagga aaacaaaaca atcacaagtt
    25501 tctactctcc acgtcatcac caagaaagca attatgaact attcagcgct ggatgggcgc
    25561 aggaagtata cgaaaaagat atggaagagt tgacaaatgc agaatttgtt ttggctatcc
    25621 ttgactttga gcatcaaaca atcgatccag gaacggctta cgaattaggt gtggcaacta
    25681 tgttgaaaaa accgatgatc atcgtacaag aagagacggt acctacgaac ttgatgatta
    25741 cacaaagtct tcacacgtat ttaaaatcag accaagctgt acgtgaatat gattttgaaa
    25801 aattgcctgt tgaaacttac gtaggcgagt acttatagaa gaggaagggt tgtatgtcag
    25861 tgattttgat ttcaggaacg attggtgcag gtaagagcag tttgacggat atgcttgcaa
    25921 aagagattga ttctaaacca ttttatgaaa atgtcgaaga taacgaagta ttgccgcttt
    25981 tttattcaaa tcctgagcag tacgcatttt tattgcaaat cttctttttg aataagcgat
    26041 ttttagcaat gaaaaatgct ttagtgaacg atgacaatgt gctagaccgc tccatctacg
    26101 aagatagtct gttgttccat ctaaatgctg atttaggtcg ggtaacggat atcgaagtac
    26161 agcagtacga tagcttatta gatacgatgc taaacgagtt agatgatgtt gctccaaaaa
    26221 aacgtcctga tttgatggtc catatcaaag tttctttgga cacgatgcta gaacgtatca
    26281 aaaaacgcgg gcgtgactat gaacagctag aaagcgatga aacgttatac acctattacg
    26341 aaacactgaa cacccgctat aatcaatggt atgaggattt tgatgtatgt cctaaaatac
    26401 aagtggatgg ggatacattc gattttgtag aaaatccaga agatgcaaaa aaggtgattc
    26461 gtcagatcca agaaaaatta gctgaattgg aaggaaagcc tgctggaaaa tattttacag
    26521 ataatcagca tgcgaaaggt caagaattag gctaaaagta aaaaaccaaa cgacgggaaa
    26581 gaaaaattac tacgtgatgt agaataagtc tttctatcgt ttggttattt tatattcaaa
    26641 gatgtgaaat aaataaaacg ttactctttg atttgtgaac tgaaatgatc cactgtttgt
    26701 tttactgatt ccagtttttg aagcttgatc aaaggaagaa gctgagtttg aagttcataa
    26761 aaatcagcca tagtgagttt tgcttgattt tgcttatctt cttttgcttt ttacataatt
    26821 tttgacagga taagattcaa acgatttaaa agaatctttg actagtttgt ggcaattgtc
    26881 gcatatactc aaacttcctt gatcattaaa ttctgtatgg atatttttgt tgttattaca
    26941 tgtacaataa tcaggactat cgatcatcca tttcgtctcc tttacagtca tcttgcttct
    27001 ttactatagc agaaaagaag gggagaaaca aaagaagatc caacagatgg cactatagac
    27061 tgtagatgtt gccatcctta tccttcaaac ggtaattacc gattttggta aatgtgactg
    27121 ttgcttcttt tttattttct tttcctgaaa taatatattc gtcatctttg gtagtaatct
    27181 tgatatctgt cagcactgtt ttttcttcag atgattcaga agaatcagct ccttgtgtct
    27241 gatacgtgcg tgtccattcc atttttttat ctgtaaatgt caactgtccc gcggataaat
    27301 ccatatcttt acgtactttt agcgtatata cactgttggt gatatctgct ttttccgctt
    27361 ttaagacaga agaatcggtt gtttcgtccg aggattggtc agagccgcca aacaaatcac
    27421 agccagtcaa tgtcaaaagt cccgcagaca aaataaatag tacgattaat ttcttcaaaa
    27481 tacttccccc atttgatagg ataaagaaat tataccattg gaaagtaaaa cttcaaacgg
    27541 atggaagaga aaaaattcac aaaataccat taaatagaat aatttttcaa aagtcataaa
    27601 aaatccacca cctttagaaa gcgttttaaa aaaatgtgtt gcaatcttta aaaaaagtgc
    27661 tatattaaaa atgaaccggt tcaattttag aatctaggag atgaaataat gaaagtcgta
    27721 gacagactat ctgaaaaaat gctaccaatc gtatctaaga tgagtagcca gcgacacttg
    27781 ctggccattc gagacagttt tatcgttact atgccgttag taatggctgc ttctgtcatg
    27841 gttttgctga atgctctgat tttttcaaat gcaacagtcc aaagaatact tgatctaagt
    27901 ccattggctg aacttgcttc aatcgtgaat aatggtacga tgagtatttt agctattatc
    27961 gtgtgttaca atatcggctg gaatttggca acccactata tccaaacagg cgtgattgat
    28021 gatccatcat ttagtcctgt tcatgcagga attctaagta cagccgtaat gtttattttg
    28081 atgtctttat caagtacagt cactttgatg gacggaaata cagcagaagc tacaggggtt
    28141 ttcttacaaa gtctgacttc ttcgtctggc ttagcaacgg cgatgattgc tgcccttgtc
    28201 agtacagaat tatttatcaa attagcgaaa atgaagagtt ttaaaatcag gatgccagaa
    28261 ggagttccac cggcagtagc tgcgtcattt aattctttag taccagaaat agttgtcatt
    28321 ttattttttt cagttgtcgt ttttacttta aaccatacga ctggtttgaa tgttccgcaa
    28381 ttaattgaat tagcgattca gacaccattg aaagcttttg ttttatccgt cccaggcatc
    28441 ttatttttac agtttttctc tgatttctta tgggtgtttg gtatgcatgg ttcgagtatt
    28501 ttggctccta tacggcaagc acctttgtta cagtctattc aggaaaacat ggatgctttt
    28561 tcagtaggaa aagaaattcc taatattatt acggagccct ttaccaatgc atttggattg
    28621 atcggaggtg gcgggtgtat tttaccgtta gttattgcta tcttgtgggc ttctaaacgt
    28681 caagaacagc gatcaatcgc taaatttggt ctgactactt gtttatttaa tattacggaa
    28741 ccaattatgt ttggattacc agtagtcatg aatccaatat atatgattcc atgcgctatt
    28801 ataccatcta ttaacttggt tattgcctac gcagccacaa gtcttggaat catcagtaaa
    28861 acagttgctg ctgcaccttg gatcactcca ccggttatac aatcttttat tgctacagga
    28921 ggcgatatac gagcagcagt cttaacagta atacttatca ttctagatgt atttttattc
    28981 ctgccatttg tattagccgc taataaggca aaattggcag aaggaggata ttaaggtgta
    29041 cgattacccg tatcaaaacc caaagttaac catccgccaa agagtagaag atttactttc
    29101 gaggatgaat attgctgaaa aagtaggaca ggtaaaccag catttgtatg gttgggaatg
    29161 ttatgaaaaa aacggagaca agatcgaatt aacagaaaag ttaaaagaac atgttaaatg
    29221 gggaggcggt ctgggtgcct tatacggtct gtttcgctct gatccgtggt ctaaaacaga
    29281 ttataagaat gggattcctg caaaagaaag ctggaaggtg gctaacctag tccaagaata
    29341 tgtactacag cattcgcgat ggaaaattcc agttttgctt gtagaagaat gtccacatgg
    29401 tcatcaaggc ttggatggga tttcttatcc aacgaatatc ggccgtggaa atactttcaa
    29461 tgtagcatta ttagaacaat cgagtcgatt gatggcaaaa gaactggctg ctaaaggtgt
    29521 tcatttagcg ctggtgtcga ctttggatct ggcaaaagat cctcgttggg gaaggacaga
    29581 agagtgcttt ggggaagatc cgattctctc agctcgtttt tctgaagcgg tcgttcgagg
    29641 gttccaagga gagattattt cagaaaaagt ttcttttctt gatcagacag tagaggaaat
    29701 caataagaag aaggatcaga tcggtgttgt gttaaagcac tgtatcgcac aaggagaagc
    29761 tttaggcggt cataattcag gcacagtaac gattggacgc agagagttct ccgatattta
    29821 cggaccatta ttgaagagta caagaaatgc agtaggtgtc atggctgctt ataatgacat
    29881 cgacgggata ccttgtcata tcaatcgagc gctttttgag caaacattaa gaaaagagat
    29941 cggttatcaa ggaatcgtta tggcagacgg tgtggctttg gatcgtttat ccgatgtttt
    30001 tacagataaa aagactgctg cagcatatgc attagcggca ggaatcgatc tcagtttgtg
    30061 ggatgagacc tataccaaga ttgcagaagc cattgataat caagtcgtag atgaaaagct
    30121 actagatcaa gcagttcgcc gagttttatc tgtcaaattt ttattaggtt tatttgaaca
    30181 gccatttgca aacgatccaa aggagtattg ggatcatctc atggaggaat cagagcactt
    30241 aaatttagag acagcaaaag aaagtatcac tttactaaaa aatgacggta tattgccgtt
    30301 ggatcaacaa gtaaaaaaca ttgctgttat aggtccaaat gctcacgatg tttaccactt
    30361 gttgggagac tactctgcac cacaaacaga agaccgtttg aaaaaaaaga tagtacaaga
    30421 gataaaaaca gagtttcccc aatcaaaggt ttcttatgca caaggatgtg aagtaagaaa
    30481 tcaggaggat caggaagaaa aattattaga agcggtgacc cttgctcaaa actcagatgt
    30541 gatcattgca gttctaggtg gatcaagtgc gcggaacttt gatatggaat ttcttcgtaa
    30601 cggggcagtt tcatcgaaag ggatcaacat ggattctgga gaaaatgtag atgttgcttc
    30661 tctttcttta ggtggatacc aagaacagct gattgaacaa ttgtatcaac taggcaagcc
    30721 aatcatcacg atacttgtgc aaggaagacc ctacgatttg atgaaaatcg agtcatttac
    30781 gaatgccatt gcaacagcat ggtttcctgg acaggagggt ggaaaagcca ttgcgcagat
    30841 gatttctgga agaaataacc caagcggacg attgagtttg tcttatccta gaaatagtcg
    30901 gcaactacct gtttattact atcagcgtgc tgcttctaaa caagagaatt attatgattt
    30961 aagcggaagt ccattttatc cttttggaca tggtctaagc tatacaacat ttgaatacag
    31021 tcagatggaa gtcaaaacgg atattgacaa agtaataata tcaattaaag ttaaaaatac
    31081 aggaagtgtt tcaggtaaaa caagtactct tgtctatgtc cgattaattg acggcgttgt
    31141 catccaaaga acgaaattat tgaaagcttt tcgtaaagat gaattgcggt ctcaagagga
    31201 aagactgctt gtttttgaac tcacttctga agactttagt tatatggata ttgatgacaa
    31261 gcggcattat gcaaagaaag cggtcatcat ggtcgaacaa caagaaaaag aaatcaaatg
    31321 taactggcag gagtgaaaat gtatggcatc gatccgtgac gtggctaaga tggctggtgt
    31381 ttcagtggga acagtttccc gctatttaaa cggtcagcag ctgaaggaaa agaatatgga
    31441 aaaaatatca gaagcgattt cagcgttgga ctataaagaa aacatcattg ctaaaggatt
    31501 gaagaataat cgaagtttct ctattggact gttgataaac gggatatcta accgatttgg
    31561 ttcggaggtt gtttcaggga tcgaaagagt agctgaagaa aatgggtata gcttattatt
    31621 aagcgggttt gccgatcagc cagaaaaaat cgaacaaaaa atcgaatacc tgatgaagca
    31681 tgcgatcgat ggattgatcg tcttcttatc agaagaagag tggtctggat ttgaaatgct
    31741 gacaaaaatg agtatcccag ttgtcgcatt gaattgtccg ggtgggccag caggtattga
    31801 tacaatagta gtgaatgatc gagaaagtgt agcaaaagtg attgctcatc atggcggaca
    31861 aggacataaa acaataggat ttattgctgc cgctcaaaca gattacgtag caagagaacg
    31921 tttagctgga gccaaagaag cggtacaaaa ggatccgtct atccatttag agatctttac
    31981 aggagactat tctagaaaaa gcggctatta cggggcaaaa gcattattag aaaaaggggc
    32041 aactgctatt tttgtcagca attacaacat gtcgattggt gccatcgaat gtttcaatca
    32101 agaaggtgtc agaatcggga aggatattgc gttcagtcac tatgattatt tagataaaaa
    32161 cgatctgagt atccttccaa aaatcacgat cacgccacca acagataaaa tcggggaacg
    32221 agcagcagaa cagctgttga aacgaatcaa aaaagaagag gaagaaaatg aaaaagtgat
    32281 tgtgatggaa aatatcatac atggaatcaa ctaaaaaaga aaaagaggtg ctttgatgaa
    32341 aagatatcaa tttccaaaaa atttttggtg gggctctgca gcaagtggtc cacaaacaga
    32401 aggaagaatt tcaggcgatg gaaaaggaga gaatattttt gattattggt acaaaaacga
    32461 accgcaaaag ttctttgatc aagtaggacc tgaaaaaacc tcgcaagttt atacgaagta
    32521 tcaagaggat gtacagttga tgaaacagac tgggcataat tcatttcgaa cctctatcca
    32581 atggagccgt ttgatacctg atgaatctgg aacaatcaac gaagaagccg ttcgtttcta
    32641 tcatcactat tttgatgagt tgattgaaaa cggtatcgaa ccctttgtta atctgtatca
    32701 tttcgatatg ccgatgtatc tgcaagaaaa aggcggatgg ttgaaccgag aaacggttga
    32761 agcctatgaa aaatacgcaa aaagttgttt tcaattgttt ggctcgaaag taaaaaaatg
    32821 gtttacccat aatgaaccaa tcgttccagt cgaggcaggc tatttgtatc gatggcatta
    32881 tccggaagaa tcagatatga aaaaggcaat ccaagttggt tatcatgaag cgttggcttc
    32941 agcattagcc atcaaagctt accatgaaat ggatcaaagc ggtgtgatcg gaatcatctt
    33001 aaatttgaca ccgagttatc caagagacga atcaaatccc gaagatgtta aagcagcacg
    33061 aatagcagat gcgttcttca atcgttcatt ccttgatcca gctgtaaaag gcgagtttcc
    33121 cagtgaattg attgagagaa taaaagaact cgatctaatg ccggagattc atccagatga
    33181 tttgacgatc attaaagaaa acacagtaga tcttttggga attaattatt accaaccacg
    33241 ccgaataaaa gcaaaagaaa caccaatcga tactaaaaac ggtcctatgc ctgaggatta
    33301 cttcgacaat tatgaaatgc ctggtcgtaa aatgaatcct tatcgcggat gggagatcta
    33361 tgaaaaagga atctatgata ttttgatcaa tgtacgagat cattatggga atatcgactg
    33421 ttttatttct gaaaacggca tgggtgtaga aaatgaagca cgatttatca aggaagatgg
    33481 tatgatccac gatgattatc ggatcgaatt tgttcaatct catctgaaat atgtccatca
    33541 agccattcaa gaaggtgcca attgtttagg ttatcatatg tggacatgca tggataactg
    33601 gtcgtggacc aatgcctata agaatcgtta cggttttatt tcagtagatt tagcacaaga
    33661 tggaaaaaga acgatcaaga aatcgggtca ttggttcaaa gatgtatcag acagaaatgg
    33721 atttgaagct taaagaatag ccaagagaga atgtatgaaa attcccgttc ttaccgcttc
    33781 aggaaaaaga agttcaatta tttacgatct ttttcaactt ttttgtcttt ctatttcatt
    33841 ttttgtatat aatagaatag tcaaaattaa ataggagtgg aggaaggcat gaggaaaaaa
    33901 agaccgtttc ttctcttttg gttattcggt tttttcttac tgcttatttt atccgcagca
    33961 ttttcaggaa aaatgacagc agatcttgct cagaaagaaa cagaaaaaat cgtagcaagc
    34021 aaagaatcag tagataattt caaaaaagaa ttctcaactt attggtggga ggaatataaa
    34081 ttaactgcca attacgaaaa aggtgaattg gacatctatt tgccaaaagg aaaagaagaa
    34141 aatcaattta tcaatatcga tgacgtactt agtgcgattt ctctcagaca atatcaattc
    34201 aaagacaaac atttggtcgt tttgcttttg actcatgatg gcgacaaggt agcacgtttg
    34261 aaaaatggaa aagtggttac agcttattct gaaaaagtgg acaaaaaagt ggtggccgat
    34321 cgactagcgg aatggaaaaa gaccaacgaa caagtcaaga aaacaactgc ttcttctcaa
    34381 aaaaacgagt cgacagaact aagcccttca gattctggca gtggacaaac gataacggga
    34441 aatgaagaaa atcaagcctc aatcattacg aatgagtcat cagaaggaca atatcaaacc
    34501 tatggacaat gaaaaacaga agttgtgaca gaagtggtca gcttcaagaa ataagaagaa
    34561 atttacgaaa agtgcttctc aagtttttgt aaaatttcgg cttatttccg aagaagctac
    34621 ttctggaaca ccgtgaatca gaggttgtga aatcagcggt ttgacct
//
LOCUS       DACGMI010000031        34643 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.032, whole genome shotgun sequence.
ACCESSION   DACGMI010000031 DACGMI010000000
VERSION     DACGMI010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.032"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            598..1287
                     /locus_tag="IXT46_001600"
     CDS             598..1287
                     /locus_tag="IXT46_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4947517.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="IXT46_001601"
     CDS             1274..2482
                     /locus_tag="IXT46_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4947518.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="IXT46_001602"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="IXT46_001602"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAQ4947519.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="IXT46_001603"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="IXT46_001603"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAQ4947520.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6585..7280)
                     /locus_tag="IXT46_001604"
     CDS             complement(6585..7280)
                     /locus_tag="IXT46_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAQ4947521.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="IXT46_001605"
     CDS             complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="IXT46_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAQ4947522.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8479..8670)
                     /locus_tag="IXT46_001606"
     CDS             complement(8479..8670)
                     /locus_tag="IXT46_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAQ4947523.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8691..9581)
                     /locus_tag="IXT46_001607"
     CDS             complement(8691..9581)
                     /locus_tag="IXT46_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAQ4947524.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9568..10335)
                     /locus_tag="IXT46_001608"
     CDS             complement(9568..10335)
                     /locus_tag="IXT46_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4947525.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="IXT46_001609"
     CDS             complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="IXT46_001609"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAQ4947526.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="IXT46_001610"
     CDS             complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="IXT46_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAQ4947527.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="IXT46_001611"
     CDS             complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="IXT46_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAQ4947528.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14951..15289
                     /locus_tag="IXT46_001612"
     CDS             14951..15289
                     /locus_tag="IXT46_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947529.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(15457..16215)
                     /locus_tag="IXT46_001613"
     CDS             complement(15457..16215)
                     /locus_tag="IXT46_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAQ4947530.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16233..17051)
                     /locus_tag="IXT46_001614"
     CDS             complement(16233..17051)
                     /locus_tag="IXT46_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAQ4947531.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="IXT46_001615"
     CDS             complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="IXT46_001615"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAQ4947532.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="IXT46_001616"
     CDS             complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="IXT46_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAQ4947533.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18179..19513
                     /gene="dnaA"
                     /locus_tag="IXT46_001617"
     CDS             18179..19513
                     /gene="dnaA"
                     /locus_tag="IXT46_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAQ4947534.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19711..20841
                     /gene="dnaN"
                     /locus_tag="IXT46_001618"
     CDS             19711..20841
                     /gene="dnaN"
                     /locus_tag="IXT46_001618"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAQ4947535.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21070..21312
                     /gene="yaaA"
                     /locus_tag="IXT46_001619"
     CDS             21070..21312
                     /gene="yaaA"
                     /locus_tag="IXT46_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAQ4947536.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21299..22423
                     /gene="recF"
                     /locus_tag="IXT46_001620"
     CDS             21299..22423
                     /gene="recF"
                     /locus_tag="IXT46_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAQ4947537.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22420..24366
                     /gene="gyrB"
                     /locus_tag="IXT46_001621"
     CDS             22420..24366
                     /gene="gyrB"
                     /locus_tag="IXT46_001621"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAQ4947538.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24386..26857
                     /gene="gyrA"
                     /locus_tag="IXT46_001622"
     CDS             24386..26857
                     /gene="gyrA"
                     /locus_tag="IXT46_001622"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAQ4947539.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27093..27392
                     /locus_tag="IXT46_001623"
     CDS             27093..27392
                     /locus_tag="IXT46_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAQ4947540.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27442..27954
                     /gene="ssb"
                     /locus_tag="IXT46_001624"
     CDS             27442..27954
                     /gene="ssb"
                     /locus_tag="IXT46_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAQ4947541.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27980..28216
                     /gene="rpsR"
                     /locus_tag="IXT46_001625"
     CDS             27980..28216
                     /gene="rpsR"
                     /locus_tag="IXT46_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAQ4947542.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28359..30332
                     /locus_tag="IXT46_001626"
     CDS             28359..30332
                     /locus_tag="IXT46_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAQ4947543.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30338..30790
                     /gene="rplI"
                     /locus_tag="IXT46_001627"
     CDS             30338..30790
                     /gene="rplI"
                     /locus_tag="IXT46_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAQ4947544.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31064..32431
                     /gene="dnaB"
                     /locus_tag="IXT46_001628"
     CDS             31064..32431
                     /gene="dnaB"
                     /locus_tag="IXT46_001628"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAQ4947545.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33211..34503
                     /locus_tag="IXT46_001629"
     CDS             33211..34503
                     /locus_tag="IXT46_001629"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAQ4947546.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10556 a         6735 c         6844 g        10508 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca taacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caagtagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgtggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtat attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
     6421 ggacttaata ccgagaaact ggcttttgaa caccgtttat cgtaaaaagg gactgtgaca
     6481 agacttttgt cacagtccct tactattatt taactatgga taaacaaaat gaggttcttt
     6541 actaccccta gatatctagc aaaatagctg atctttttgc tagtttatct tcttgggacg
     6601 gataaacttc caataatccc gtattttttc ttcaagtagt aacggattgc taaagcagtt
     6661 gccccgataa tgataactac tactggatct aatactggat tgataactgg tggcaatagt
     6721 gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc cacctaggat aagcaatgtc
     6781 ttacccattc ctggtttctt gcttcgatct gctccgggat attcatattg atagatgtat
     6841 ttgtacatca tataaaagac ccagccaccg attgcagaac ctagaacgag tgtagaaaag
     6901 ccataagctg gcgttgttcc acgtgaaaac aatccggtaa tcgcaatcat gatacttaat
     6961 agaccaagca acagcaacgt attatctaac cacatcaata aaggggtgga tgaatttttt
     7021 acttctgctg gcttattgat gattgcttcc gttctttcag agactgtccc aaacaattga
     7081 cgggctgttc ttccgccttt ttgttctgca actaaagtag gcagaatgtc atgaagggct
     7141 tttacttttt cttcttcaga caaattcgct gcttctaaag attttttcaa atcaaaaatg
     7201 tactgttgat ttcttttggt taattttgtt tctaaactat tgttttcttt tacgattgct
     7261 cgtaattgtt ctggttccat tatctaatag tcctccttag ccgttccttt tctcaacggt
     7321 cgtcacaaaa gacattctac catattctac agctagtttg atagcccttt tacacattaa
     7381 agcggaataa cattacgtcg ccgtcttgta cgacataatc ttttccttct aatcgaacac
     7441 gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc caagtcttca aaagagacag
     7501 tttctgcacg gataaatccg cgttcgaaat ctgaatggat gattcctgct gcttgtggtg
     7561 ctttgattcc ttttttgaat gtccaagcac gtacttcttg ttccccagca gtaaagtaag
     7621 tagctaagcc taacaaatca taagcagcac ggatcaactg atccaaacct gattcttcga
     7681 ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc taattctgcg atttcttctt
     7741 ctgcacgagc actgaccacg atcacttctg cattttcttc tgcagcaaag ttgcgcactt
     7801 cttgtacata atgattcgcg tctgcatctg ctacgtcatc ttctgagaca ttggctacat
     7861 aaagaattgg ttttgtcgtc aataaaaata gtgatttaac gattttttgt tcttcttcag
     7921 taaattcgat cgttcgggca gattttcctt cttccagtac aggtttgatt ttatccagta
     7981 cagctagttc tgccactgca tctttatctt tggttttagc aacttttgct acacgagtat
     8041 agcgtttgtt gatagattct aagtctgcta acactagttc caagttgatc gtatcaatat
     8101 cttctagtgg atcaacacgt ccttctacgt gagtaatatt atcatcatca aaacagcgaa
     8161 caacgtgaca aatagcgtct acttggcgga tatggcttaa gaattgattt cccaaacctt
     8221 ctcctttact tgcgcctttt acgattccag caatatctgt aaattcaaaa gtcgtcggaa
     8281 cagttttttt cggatgtaca agttctgtta agcgttgcaa acgccagtca ggtacttcta
     8341 ccatccctac gttggggtcg atcgtcgcaa agggatagtt tgctgcttct gctcctgctt
     8401 ttgtgatcgc attaaacaaa gttgattttc ctacgttggg caacccaaca attccagcag
     8461 tcaatgccat aaatttattc actctttctc tgcatttttt tcaattactt tttttaattt
     8521 cttttcaaaa tctcgacggg tcatcatgac gatatgtccg caattcatac atctgatttt
     8581 gatatctgcg cccattcgaa tgacttccca gcgattcgtc tggcaagcgt gaggtttttt
     8641 catttcaacg atatcgtgca agtcgtacat aaaaatagcc tcctttttgt ttattcttca
     8701 tcaaattgaa tattcaagat atcaagaatt cgagtcaaat ctttttgaga aagatattca
     8761 atctcgatct tacctttccc atttttttct tggatagcta cacttgtacc aaatttatcc
     8821 atcaaacgat cttcgctttc tcggatataa tatggttttt cctttgctag ccttgggatt
     8881 tttttctttt cttttccatc attttgattt aactcagaaa caagctgttc cagttggcgg
     8941 acagttaaat tttcagttac tgcacgattg gctaatttca agatcaatgt tttatttttt
     9001 aaacctaaca gcgtacgggc ttgtcccata gataaacgct gatcttgtac catttccttg
     9061 acaagatccg gtaaagaaag caagcgcaaa taattggcga tataaggtct gctctttcct
     9121 aaacgactag ctacttctgc ttgtgttagt ttcaggtttt tcatcagcat ctcatatgct
     9181 tctgcttctt ctaacggatt cagatcttct cgctgcaagt tttccagcac tgctacttgc
     9241 atcatcgctt cttcgtcaaa gtctctaacg atagcaggga tcgtttcttt ttcagctagt
     9301 ttggacgctc gaaaacgtcg ctcccctgca ataatctcat atccttttac tgcggaacgg
     9361 cgtacgatga tgggttgaaa gacacctgat tgttcaatag aattagctag ttcctgcaaa
     9421 gatacttctt caaatgtttt acggggctga tacggatttg gtcgcagctc attcaatggt
     9481 agctggacaa cggtatcatc ttttacatcc accgtctcta agttttctaa atcttgaaac
     9541 agtgcatcga ttcctcggcc taatccttta cttttcttca cgacttacca cttcctttgc
     9601 caatgcttgg tagacttcag ctcctcgaga acgtggatcg tagtcgatga tcggttttcc
     9661 atgactaggt gcttctgata aacgaatatt tcttggaatg atcgtttcgt aaactttttc
     9721 gcggaagtat ttacgtactt cttctacgac ttcatttccc agatttgttc gtgcatcata
     9781 cattgtcagt aagactccct cgatctctaa ttctggatta aagtgttttt ggactaaacg
     9841 aaccgtattc agtaattggc ttaatccttc caatgcgtaa tactcacact gaacaggtat
     9901 caaaatcgaa tcacttgctg taaatgaatt gattgtcaga tggccaagag aaggcgggca
     9961 atcgatcaaa atataatcat actgactgct tacttctgct aaagatcctt ttaatcttga
    10021 ttctcttgcc atcattgacg tcaattcgat ctctgctcct gctaattgga gagtcgcagg
    10081 cacaatactc aaattttcgt gttcagtgat caaagttgcc tcatcaattg gcaattcatt
    10141 gactagaaca tcatagatgt ctcttgtcac atcaggtttt ctgatcccga caccactggt
    10201 agcatttcct tgtgcatcca tatccactag caatactttt ttgccaaggc tagcaagaca
    10261 agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca cctttttggt tcgcaacaga
    10321 tattatttgt gccatctctt ctcctcctat ttgattggct gcttattagg cagtccgggc
    10381 tttcttgggt atttctttgg ggttggtttc tttttttgaa taacgatgat atgccgttga
    10441 tcagagacat tcggcaaggt aaccgcctct tctttgagga atttaccacc taataaagca
    10501 atcgcttgtt ttgcttctgt caattcctct tcactttttg ctgctttcaa tgcataaaaa
    10561 tagccttctt gtttagccaa gggcaaacac aattccgcta acacattcaa acgagcaacc
    10621 gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag gattttgccc aaatgtttct
    10681 gcccggtcat gatataagga agcatcgatt cctaataatc gggttaactc agataagaag
    10741 gttattcgtt tattcagaga atcaacgatc gttatctgca gttctggaaa ggcaattttt
    10801 aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc ataaagataa aggttgcgta
    10861 aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat gcttcagata tacgtctttt
    10921 tcatccgtaa tagctgtaag gttcatcttt tcgttccatt cgactaatgt ccgataataa
    10981 atagcgaatt gattcatttg atgatcggta agctctatcc ctttttctgc caaggattgg
    11041 cgaaattctt ctggtatcat aaatattcct ttcattgtga aacagcaatt gtttcacaga
    11101 ttctctccct actttaacgc aaaatctcta gacatgcaat ccttccatat ggattcttaa
    11161 aaatttgaaa agtaagaaaa gccgatagac tttttctttc tagtatgact cataaaatat
    11221 acacagaaga gagaactagc tttgagcaat ttctgcaaaa actagttctc tcttctattt
    11281 attattacgt attacgctgg ttcactgact ttcgcaatct tcccttgttc gatatagacc
    11341 attaggatac ttaggtctgc agggtttacg ccactgattc ggctagcttg ggcaattgtt
    11401 tctggttgga ttttctgcaa tttttgtttt gcttctgttg ctaatccgtt gattgctgcg
    11461 tagtcgatgt tttctggaat ctttttcgct tccatgcgtt ttaatttttc tactttttcc
    11521 atggcttttt tgatgtagcc ttcatatttg atttggattt ctacttgttc gatttctttt
    11581 cgtgtcaatt cttcattttc tggaataaac cgtagaagtt ctgcataagt aatctcagga
    11641 cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg gtgccgcatt aatcgttgct
    11701 aaaaagtctt ggacttcttc tgttggtttg attcgtacat tcatcaaacg tttgatttct
    11761 tgttcaactg cttctttttt cttcaaataa ttcttgtatt gatcttcttt tactaagcct
    11821 acacggtgac ccatttctgt taatcgcaaa tctgcattat catgacgtaa aagcagacgg
    11881 tattcagcac gtgaagtcag caaacgataa ggttcgttcg ttccttttgt taccaaatca
    11941 tcgatcatga caccgatgta accgtcactt cgtttgatca ctaaaggttc ttttccctga
    12001 actttcaaag ctgcattgat accggcaatc agcccttgtc cagccgcttc ttcataaccg
    12061 cttgtaccat ttgtttgtcc agctgtataa agattttcaa cgactttagt ttctaatgtc
    12121 ggacggagct ggtgtggctc tactacgtca tattcgatag catatcctgt acgcatcatt
    12181 tctacttttt ctaatccagc aatagaatga agcatgttga cttgaacatc ctctggtaaa
    12241 gaagtagata aaccttgaac atagacttct tccgtattta agccttctgg ttccaaaaat
    12301 aattgatgac gtggtttgtc tgcaaaacgc acgatcttat cttcgatgga tggacaatag
    12361 cgagcgccta ccccttcaac gatccctgta aacattgggg cacgatgtaa gttgtctcga
    12421 ataatttggt gagtcgtctc acctgtatag gtcagccagc aagattcctg atctagttta
    12481 taggcactat ctggtgtgct gaagctaaaa tgattcggct ctttgtcacc aggctgctct
    12541 tctgtaacag aatagtcgat cgtacttgat tttactcgag gcggtgttcc tgttttgaac
    12601 cgttcgatag caaagccaag ttcttttaga tgattcgcta gtccaataga aggttgagag
    12661 ttattcggac ctgatgaata tttcaattca ccgataatga tttctccgcg aagtgctgtt
    12721 ccggctgtaa taacaactgc tttggcccgg tagctcgctc ctgtggacgt cactactcca
    12781 tgacaaacac catcttcgac gatcagttct tcgacgattc cttgtcttag cgtcaaattt
    12841 ggttcttttt cgatcgtatg tttcatttct gttgaataag catgtttgtc tgcttgtgct
    12901 cgcaatgctc ggacagctgg gccttttcct gtgttcaaca tacgcatttg gatataggtt
    12961 ttatcgatat tcttacccat ttctccgcct aacgcatcga tttctcgaac gacaacgcct
    13021 ttagctggtc cgcctacaga aggattacat ggcatgaatg ctaccatgtc caaatttatt
    13081 gtcagtaata atgtttttga tcccatacgt gcagcagcaa gtgcagcttc tgaaccggcg
    13141 tgtcctgcgc caacaacgat cacgtcatac gcatctgctt cataatgttc caatcgtttg
    13201 ttcctccttt tattttccta aacaaaattg actgaataat tgagtgatta gctcatcttg
    13261 tacactgtcg ccgacaactt ctcctagata gtcccagcaa cgcgtcatat ctatttgaac
    13321 gagatccaca ggcattcctg aatcaatacc tgcaatgact tcttcaagtg agagggaagc
    13381 tttttctaac aacgcgatat ggcgggtatt agaaacataa gtagcgtctc tttctcctgt
    13441 ttctccgctg aagaataaat cagaaatagc tgattccaaa cgatctagtc cgtcgttttt
    13501 agctacggaa attgaaaaaa ctggttcatt ttcgatcaat ttcttcaatt tttcttgttc
    13561 cagctgtgct ggcaaatctg ttttatttag aagaatgatc cgtttcaatc cacttgtcgc
    13621 ttccaataat tgttcatctt ctgctgtcag tggttcgctt tggtttagaa caagtaagat
    13681 caagtctgct tctgctaatg cttttcggct tctttcgacc ccgatccgtt ccaccacatc
    13741 ttctgtttcc cgaattccag ctgtatcgat tagcttgagc ggtacccccc gaacattgac
    13801 atactcttcg attacatctc gagtcgttcc tgcaatatcc gtaacgattg ctttttcttc
    13861 tcttaacaaa tggtttaaca aacttgattt gccgacattt ggccggccga tgattgccgt
    13921 acttaaccct tcccgcagaa ccttcccttg cttggatgta gcaagtagcg cttggattct
    13981 ttgttggatc atctgcgctt tttcaagcaa taacttcgta gtcaattctt cgacatcatc
    14041 atattctgga taatcaatat ttacttctac ttgtgctaat gtctctaaaa tctcttgtct
    14101 caatgagcgg atcaaagcag acagattgcc gtctaactga ttaagagcta gtcccattgc
    14161 tttgtctgtt tttgcccgaa tcaaatccat cacagcttct gcctgtgaaa ggtcaacacg
    14221 accattcaag aatgctcgtt ttgtgaattc gcctggctca gctaatcttg caccttctct
    14281 taacaatagc tgcaaaattt gattgactac aacgatccca ccgtgacaat tgatttctac
    14341 tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg gagaccatga cttcatcgac
    14401 aagctgattg ctcttgggat caacgatatg tccataatgg atcgtatgac ttggtacttc
    14461 tgataatcgt ttgtttccag attgataaac tttatctgct agttgcacag cttgatcgcc
    14521 acttaaacga acgatactga ttgcaccttc tccaggtggg gtagaaattg ccgcaatcgt
    14581 atcaaattct aaagtaattt cagccatttt ttcacttcct ttttcatttt gcgcacaaaa
    14641 aaagtgccca ctccaccctt tatgcacaat aaacggtgaa cttcgcactt tgactgcttg
    14701 ttcttgatta aattctggtc atagattatc acacttgcta taaggaatca agtgtttaaa
    14761 acaattagat gaagttgagc ctgttctgct tccattacct tatatttaat tgtccttgga
    14821 tgtctctttg cgttctttgg tttattcgaa gagaagatac tgtataaaca aggctttatc
    14881 tttcttaaaa aaaacggtac actaaatggt agcgctatct aaactataca cttttgaaag
    14941 gagaaaatat gtgagcccgt tcagatctgc tgcattggaa gaagaaagtg accctcggat
    15001 caacgatgtc gttttatcta cagggaatat caaccagaaa tatatcgtcc gcgatatcgt
    15061 ttttgttgtg gaatgcttag aagctgattt gtttgaccca tcttttccca aagatgacct
    15121 tttcttaaca acgaagagga aattaaagac gaaggtactt gaatatggtg cgaatgcagt
    15181 aatcaactgt cattttgagt atcagcaaaa aaaacgcgac ggaaagtatt ttctggaact
    15241 ttttgcttat ggaacagtga tccaatttat ccaaacaacg attggttaaa tgaaacagac
    15301 aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct tttttctatc aaagttagtg
    15361 actacttcat cgtatactct gataagaatg atttctagta aaatatactt ggtttgaaaa
    15421 actttgtcaa cgtgatttat tcaaaaagta atggaatcaa taatattttt tagcaggttc
    15481 tactactaaa taacgataag gttcctcacc ttccgaatgt gtttttacat gttcatcttt
    15541 gcttaatgca gcatggattt gtttacgttc aaatgcaggc attggttcta agaaaacagg
    15601 ctgccctgtc cgttttactt tttcagccgt gcgatcagct aaacgctgaa tgatctcttg
    15661 gcgcttttca cggtaattgc ctacattgac tactacagac agcttatttc ttgctaaacg
    15721 atggatgaag acttgtgcca gatattgcaa tgcattcagt gtttttccat gtttcccaat
    15781 cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc atattatttg attctctttc
    15841 cattttgaca agagctggag catcaagctg ttttgaaatt tcagtaagat aaactgccaa
    15901 ttccgttaaa gctgcttcat cacctagctc acttacttct tctgtttttt cttcaagaat
    15961 cgtttcgttg actacctcga tctcagctgt tggttcttct tccaaaattt cttctacagt
    16021 ctgttctact gtttcagaaa ctttttcgct gatacttggc tggatcgaaa gccgtgcatt
    16081 ctttcgaccc attcctagga aacctttttt tccttcttcc agtatttcga tttcgacttg
    16141 gtctttggcc aaacccaaat cagccagacc tagttggaca gcttcgtcta ttgttgcagc
    16201 ttcataaatc ggcattagca ttacctcccc tattatttcc gttttttctt aggattcatt
    16261 gctttcttaa gagcacgttc tctttcgcgg attctccgtg cttcttcttc acgctctttt
    16321 cgaattttga aagggttgtt gatcagcagc gtttgtacaa cttggaaggc attggaaact
    16381 acccagtata atgaaagacc gctggctaaa ttgacaccca tcactaaaat cattacaggc
    16441 atcacgaaat tcatgatctt cattgatgca ttcgattcaa tttgactcat gctagataaa
    16501 tacgtacttg caaaagtaaa gattgctgct aaaatcggca aaataaatgt tggatccgcg
    16561 ttccctaagt tcaaccataa gaaatgccct tgtttcaact ctggtacacg tgaaatagat
    16621 tgccataacg ccatcaagat tggcatttgt actaataaag gaagacaacc agcatatgga
    16681 ttgacgccat tttctgcata taaacgctgc tgctcttctc ttaacttact ttgtgtttcc
    16741 ggatctcttg aactatattg ttgctgcagt gcttttaatt tcggttgtaa ttcttgcgtt
    16801 ttacgcatgc tctttgtttg gaaatgcatc aacggcaata ggatcacgcg gatgatcagt
    16861 gtaaataaaa tgatccctat ccctgcatta ccaaatgaca acgccttgat cgcctcagca
    16921 aagtaataaa caatataacg atcccaaatt cctgtactct gtgcgctgac ttccccagtt
    16981 ccgcaaccgg ataagacgat gaccaaacta acgataccgg ccatcaaaag taaacgtttg
    17041 tatttcttca cttactcttt tcctctctgt cgattatttt tgcaagtttt aagacgtgga
    17101 ctaaattgga gcgaacctca tcataagtca accccttcac acttggtcta gcaatcacaa
    17161 taaaatccaa ctccggatca atttcttctt ttatagaata aactgctgct cggatttttc
    17221 gtttgacttc attgcggttt accgcgttgc cgaccttttt tcctacagat aaaccaactc
    17281 gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac gaatttgcgg ttagcaaaag
    17341 aatctcccgt atggaacacg gcttgaaact ctcgttcttt ttttactcga tacgcttttc
    17401 tcattagttt tctttccttt tctatctctc acttacgctc ataatcatac cataattacg
    17461 attgtccttt catcatttcc ctaaaaaaga gtataaaaaa aaccactgaa accccagtgg
    17521 cctaagctga aagaactttt cttcctttgc gacgacggct agctaacaca cgacgtccat
    17581 ttttagtact catacgttta cggaatccgt gaactttttg acgtttacgt ttatttggtt
    17641 ggtatgttct tttcatatat tccacctcca aaatgttctt atctatttta taaacacaga
    17701 catactttga tagtataacg acaaagtagt gattttgtca atataaaata gaagatcgat
    17761 tgttaaaact tatccacaag attatttttt tctatgggaa tcctatgtgg aaaaagttat
    17821 gcacagggat tatccacaga taataaaagg ctggttttac acagaaaaca cacgtgtaaa
    17881 aaaagtaatc cacaatcagg cgatttcctg tgtattccgt ctcctaacta ttggtatatc
    17941 tgtatttttt atccacagac gcaagaggaa atctattggt ttttacgagt tttccacctg
    18001 tgcattagtg gtgtggaaaa ctttttttga caactgtgtt tttctctttt ttctttttgt
    18061 cgattgtgtg gataattgta attaaaaaat ttttttcttc ggtttctgtg gaaaactatt
    18121 gaaaaaaatg ctaaattagt actagttatt cactttttaa tgaaggagga ggccttatat
    18181 ggtatccctc gatgctttat ggaatgaatt aaaagcaaca taccaaaagg atttatcgcc
    18241 tgctagctat aatacatgga tcgaaacagc gaaccctcga acccttgatc aaaaccagct
    18301 cgttgttgag gttcctagca agattcataa agaatattgg gaaaaaaacc tggcgacaaa
    18361 aatcgttgaa gtcggttata tgttatcagg aaatgagatt atccctcgct ttattactgg
    18421 cgaagaagca gagcaagaag aagttataga agaaaaaaat ccaaaagttg tggcacctag
    18481 tccgctaaaa aaagccatgc tgaaccctaa atataccttt gatacgtttg tcattggtaa
    18541 aggaaaccag atggctcatg cagcagcgct cgttgtagca gaagatccag gttctattta
    18601 taacccgctc ttcttttatg gaggcgtggg acttggtaag actcacttga tgcatgcaat
    18661 tggtcatcaa atgctgcaaa gtcagcctaa tgccaaagta aaatatgtaa gcagtgaaac
    18721 ttttgctaat gatttcatca attcgatcca aaacaaaaca gcagaagagt tccgtcaaga
    18781 atatcgaaat gttgatttac tgctagtgga tgacattcaa ttttttgcag aaaaagaagc
    18841 tacgcaagaa gagtttttcc atactttcaa tgccttgtac aatgaaggga aacaaatcgt
    18901 actaaccagt gatcggttgc caaacgagat tccgaaactg caagaacgcc ttgtttctcg
    18961 ctttgcatgg gggctgtctg ttgatattac accgccggat cttgaaacaa gaacagcgat
    19021 tttacgtaaa aaagcggcgg ctgaacgtct agagatccca gatgacacac taagctacat
    19081 cgcaggacaa attgattcta acattcgtga attagaaggt gcgcttgttc gagtgcaagc
    19141 ttttgctgcg atgaatagtg aagatatttc gactagtcta gctgcagacg cactgaaaac
    19201 gttaaaatca ggaaaaggac atcctcaatt gtcaatcctg cagatccaag aagaagtggc
    19261 aaagtattat cacatccaat tgaaagatct caaaggaaag aaacgcgtca aatctattgt
    19321 tgttcctaga caaatcgcta tgtatttggc acgtgagctc acagataatt ctttaccgaa
    19381 aatcggagct gaattcggtg gcaaggatca tacaacggtt atccatgctc atgaaaaaat
    19441 ccagcagctg atggattcta gtgtcagtat gcaaaatgaa gtatcagaaa tcaaaaactt
    19501 tttactaaat taatttgtcg attctatcaa ctgaaaatag catgtggata aaagaaaaaa
    19561 acgttcaaaa gttatacaca ctttttccac agctgttttt tcgtttctct cttacgtttt
    19621 ttgagttttc cacagaatca acatgcccta ttacttttat tattcttttt aactaataat
    19681 aaataaacaa acattcaaag gagatacatc atgaaagtta ctttaaaccg agctagcttt
    19741 atgcaggaat tgcaaactgt tcaacgagct atttcaagca aaaccacgat ccctattttg
    19801 acaggtgtaa aaatcacact gacacaagaa ggtttgactt tgacggggag caacgctgat
    19861 atatcaattg aaactttttt gtctgttgaa aacgaaaaag caaatatgca aatcgaatct
    19921 actggttcca ttgttttaca agcacgtttc tttagcgaaa tcattcggag acttcctgaa
    19981 gaaacattta ctttagaagt tttagaaaat aaacaagtag cgatcacttc tggaaaagcg
    20041 aattttatcg taaatggatt agatgcagat aactatcctc atcttcctgt tgtcgaaagc
    20101 cataaccaga tgaaattacc tgtacacgta ttgactaaac taatcaacga aacagttttt
    20161 gctgtctcac aacatgagag tcgtccaatc ttgacaggtg tgcatttcat tttatctgat
    20221 aattctttat tagctgtagc tactgattct caccgtctaa gtcaacgcgt gattccagta
    20281 gaacaagcgg ctgatcattt tgatattgtt attcctggaa aaagtttgat cgaattatct
    20341 cgctcattaa caaatgaaga agaaatcgtc gaaatcagca ttatggaaaa ccaagtgttg
    20401 ttcaaaacag aaacgatgta tttctattcc cgtttgctag aaggaaacta tccagatacc
    20461 aatcgtttga ttccttcaag ttttaataca gaggttgaat tttctgttcc tagcttttta
    20521 gcggcgatcg aacgggcttc tttactttct catgaaggcc gtaacaacat cgttcgttta
    20581 tctattcgtc cagatgcggt tgttttatac ggaaattcgc cagaaatcgg gaaagtagaa
    20641 gaaagcttga gttatacagc aagcagtggc gatccattag atatttcttt caatccggat
    20701 tatatgaaag cagcgttgcg tgcatttgga gatatgagca tcaaagtgaa atttatctct
    20761 gctattcgtc catttacatt ggaaccaacg gaagatggcg ttcaatttat tcagctgatt
    20821 actcctgtac gtacaaatta acaatgattt tcaatgttct tgaaaattta attgaaaaga
    20881 aatagaaaaa ataaaatttt aaacagaagg ccctaaaatc tcttttaagg ctttctgttt
    20941 atttttgttt aaatcacctt ttttagatta aatcgtctta tatggaaaaa tatatggata
    21001 aatttgtttt attgcgaaaa aaaaggtata atagagtata cttttaataa tgaaaatgag
    21061 ggatgggcat tgaaacaaca agtcattcta aatacggaat tcatgacgtt gggccaaatg
    21121 ttgaaagaag tcacagttat cggtagtggc ggacaagcaa aatggtattt ggcagaaaac
    21181 actgtgttag tcgatggcga accagaaaat cgtcgtggac gcaaacttta tcccggcatg
    21241 atggttgaag ttccagaagt aggaactttt tttatggtaa aaaaaggaaa cgacgataat
    21301 gaggctgaat aagctgtatt taaaaaatta tcgaaattac gaagagctga acatcgaatt
    21361 ttccaagaac ctcgtcatct ttttaggaga aaatgcgcaa ggaaaaacga atcttttgga
    21421 aagtatctac gtattagcta tgacgcgaag tcatcggaca agtagtgagc aggaattgat
    21481 tggctggact gacgatcagg cgatgattca aggagagatc acaaaaggtt catccactct
    21541 tccattagaa atcttattat ctaaaaaagg ccgaaaaacc aagatcaacc atatcgaaca
    21601 gaaaaagtta agtacttacg tgggacaaat gaatgtcatt ttatttgcac cagaagatct
    21661 ttctttagta aaaggcagcc cgcagaccag gcggaagttt ttagatatgg aattaggcca
    21721 gatcaatcca atctatcttt atgatcttgt ccaataccaa gcaattttga aacaaagaaa
    21781 ccagtacttg aagcaattga atgaaaaaaa acaaactgat ttgctttatt tggatatttt
    21841 gtccgaacaa ctagcagcgt ttggcagcaa agtattgaaa gcaagagcac agttcgtcaa
    21901 gcgattggag ttttgggcta attctttgca tcagcaaatc acccatcaaa aagagcagct
    21961 ggaaatcgag tatctcaccg cagtcgattc tttagaaaca catacgcaag agcaaatcca
    22021 agaacaattt ctcgcacttt tgaaccaaaa taaaaagaaa gacctttttc ggggaacaac
    22081 gacagttggt cctcatcgtg acgatctttc cttttttatt aatcagaaaa atgtgcagac
    22141 ttatggatcg caaggacagc aaagaacaac tgcactaagt gtcaaattag cagaaatcga
    22201 tttgattaaa gaagagacag gggaatatcc aatccttttg ttagatgatg tgatgagcga
    22261 gctggatgat aatcgtcaac tccatctgct agaaacaatc gaaggaaaag ttcaaacgtt
    22321 cttaacaaca acgacacttg accatgtaaa aaataaaatg actgttgaac ctgagatttt
    22381 ttatgttcaa caagggaaac taaaaggaga agaaactgaa tgacagaaga aagaagttta
    22441 gtagaacgcg ctaaagagta tgatgccagt cagattcaag tacttgaagg acttgaagcc
    22501 gttcgtaaac gacctggcat gtatatcggt tcgactagtt ctgagggtct gcatcacctt
    22561 gtttgggaaa ttgtcgataa ttcgatcgat gaagtattag caggttttgc aacgaaaatc
    22621 catgtgatta ttgaaaaaga caacagtatc accgttattg acgacggtcg ggggatacct
    22681 gtagatatcc aggcaaaaac tggacgtcct gcagttgaaa cggtctttac tgttttacat
    22741 gctggaggaa aattcggcgg tggtgggtac aaagtttctg gtggacttca cggagtagga
    22801 tcttctgttg ttaacgcgct ttctacacag cttgatgtca aagtatacaa agaaggaaat
    22861 gtgtactatc aagaatatcg tcgtggagct gtagtggacg acttaaagat tatcgaacaa
    22921 acggatcgcc atggaacaac ggttcacttt acgccagacc ctgaaatttt tacagagaca
    22981 actgagtttg atttttcaaa attggctacc cggatccgtg aacttgcttt cttgaaccgc
    23041 gggatgcgta tatcgattga agacaaacga gaagaagaac cagtcatcaa tgaataccat
    23101 tatgacggcg ggattaaaag ttatgtcgaa tacttgaatg caaacaaaac cgtgattttt
    23161 ccagaacctg tatatttgga aggtgaacag caagatatcg cagttgaagt ctctatgcaa
    23221 tatacagacg gctaccattc caatatcatg agttttgcca acaatatcca tacgtatgaa
    23281 ggcggaacac atgaatcagg attcaagact gctttaactc gtgtgataaa tgattatgcc
    23341 cgaaaacaaa agctgatgaa agaaaatgac gacaacttga ccggtgaaga cgtgcgagaa
    23401 ggattgacag ctgttatttc tatcaagcat cctgaccctc aattcgaagg acaaacaaaa
    23461 acaaaattgg gcaattccga agtacggaca gtcactgatc ggttatttag cgaacatttc
    23521 atgaaattct tgctggaaaa cccaagtgtg ggccgtcaaa ttgttgaaaa aggattacta
    23581 gcttccagag ctcgtctagc agcgaaacgt gcgcgtgaag taacgagacg taaaggtgct
    23641 ttagagatta gtaatctgcc aggaaaatta gcggactgct ctagcaacga tcctgaaaaa
    23701 tgcgaattgt tcatcgtcga aggagattcg gccggcggat cagctaagca aggtcgtaat
    23761 cgagagtttc aagccatctt gcctattcgt gggaaaatct tgaatgttga aaaagcaagc
    23821 atggacaaga tcttggcaaa tgaagagatc cggtctttat ttactgctat gggtacaggg
    23881 tttggagaag attttgatgt atcgaaagct cgctaccaca aattagttat catgactgat
    23941 gccgatgtcg acggcgcgca tatccgtaca ttgctgctga ctctttttta tcgttacatg
    24001 cgtcctattg ttgaagctgg atacgtctat attgctcagc cacctttata cggggtaaaa
    24061 caagggaaga atattacgta tgtacaacca ggaaaaaatg cagaagaaga gttgaaacaa
    24121 gtcgttgctt cacttcctgc ctcaccaaaa ccaagcgttc agcgttataa aggacttgga
    24181 gaaatggatg atcatcaact atgggaaaca actatggacc caagcaatcg gatgatggcc
    24241 cgcgtcagtg tggacgatgc tattgcagca gatcagatat ttgaaatgtt gatgggggat
    24301 cgagtagaac cccgtcgtgc attcatcgag gaaaatgcac actatgtgaa gaacttagat
    24361 atttaatcat gaaggaggaa aaagaatgag tgaagaaatc agagaaaaca tccatgatgt
    24421 caatctaacc agcgaaatga aagactcctt catcgattat gcgatgagtg ttattgtcgc
    24481 acgtgcactt cctgatgtca gagatggtct gaaacccgtt catcgccgta ttttatacgg
    24541 catgaacgaa ttaggtgtaa caccggataa agcccataaa aaatctgcca gaatcgtcgg
    24601 agatgtcatg ggtaaatacc atcctcatgg agactatgcg atctatgagt caatggtacg
    24661 gatggcacag ccattcagct accgttatat gctagtggat ggtcatggaa actttggttc
    24721 tgttgacggt gacggtgccg ccgctatgcg ttataccgaa gcacggatga gcaaaatcgc
    24781 tacagaaatg ctgcgtgata tcaataagaa cactgttgat ttccaaagca actatgatga
    24841 tacagaaaaa gaaccagttg tactacctgc tcgcttcccg aatcttttag tgaacggaac
    24901 aacggggatc gccgtaggta tggccacgaa tatcccacct cataacttgt ctgaggtagt
    24961 agcggctatc gatttgctga tggataatcc tgatgtgacg accaatgaat tgatggaagt
    25021 attacctgga ccagattttc caacaggtgg tttggttatg ggaaaatcag gaatccgaag
    25081 agcgtatgaa acaggtaagg gttctattac cgtacgtgca aaagttgaga ttactgagat
    25141 gccaaatggt aaagaacgga tcatcgtgac agaattgcct tatatggtca ataaagcaaa
    25201 attgatcgaa cggatttctg aactgcacag agacaagcgt atcgaaggga tcacagattt
    25261 gcgggacgaa tcttcccgtg aaggtatgcg gatcgtcatt gacatccgtc gtgacgccag
    25321 cgcatctgtt atcttgaata acttatataa attgacatcc ttgcaaaatt catttggatt
    25381 caatatgttg gcgatcgaaa aaggtgtgcc gaaagttttg agcttgaaac aaattcttga
    25441 aaactatatc gaacatcagc gcgaagtcat cacaagacgg acagtctttg aaaaagaaaa
    25501 agcagaagca agggcacaca ttttagaagg tttgcgtatt gctttggatc atatcgatga
    25561 aatcattgcg attatccgcg ggtctaaatc agatgacgaa gcaaaagcga cgatgatcga
    25621 acggttcgat ttatccgatc gccagtctca agctatttta gatatgcgtt tacgccgatt
    25681 gaccggtttg gaacgggaaa aaatcgaaaa tgaataccaa gaactcttaa aactgattga
    25741 agatttaact gacattctgg caagaccaga acgtgttaca gaaatcatca agaatgaatt
    25801 agcagacttg aatcaacgat ttggtgataa acgacgcaca gaattactag tcggtgaggt
    25861 cttaagtctg gaagatgaag atttaatcga agaagaagaa atcgttatta cattgacaaa
    25921 caatggttac atcaaacgtt tggcaaataa tgaattcaga gctcaacgaa ggggtggacg
    25981 tggtgtccaa ggaatgggta tccacaatga cgacttcgtc aaaaatctgg tttcttgttc
    26041 tacccatgat acattgttat tctttacgaa taacggaaaa gtgtatcggg caaaaggata
    26101 cgaaattcca gaatacgggc gcacagccaa aggaatacca attatcaatt tactaggtat
    26161 cgattcgagt gaaagcatcc aggcaatcat tgcggtgacg ggagaagcag aagaaggcca
    26221 ctatctcttc tttacgacgc gtcaaggtac agtaaaacgt acttctgtca ctgcttttgc
    26281 taacatccga agtaatggtc tgatcgcaat tggtttgaaa gaagacgatg agctcgtcaa
    26341 tgtgctactg acagatggtc aatctaatat cattattgga acacataacg gctactctgt
    26401 cactttcaaa gaagaagcag tccgcgatat gggacgtaca gcttccgggg ttagaggaat
    26461 acgcctgcgt gaggaagatt atgtcgttgg ggcagcctta atgaaggaag atcaagaagt
    26521 attagtgatc acagaaaaag gttacggaaa acggacaaaa gtatcggaat atccagtgaa
    26581 aggccgcgga ggtaaaggga tcaaaacggc gaacatcact gaaaaaaatg gtccactagc
    26641 tggattgacc actgtttctg gagatgaaga catcatgctg attacagata aaggtgtcat
    26701 tatccgtttc aacgtatcga ctgtttctca aactggacgt tcaacattag gcgtacgttt
    26761 gatgaagatg gaagctgata cgaaagttgt cacgatggca gcagtcgaac cagaagctgc
    26821 agaacaaaca gttgaagaac aaggatcaga agaatagcca tcaagactaa ttgtgtaagc
    26881 tagcaagaat gaccgattaa aaaatctggt tattcctgct ggcttttttg attagttgaa
    26941 tttctcttaa aatattcgaa actgttcatt ctgtattgct tttgaccaaa atagagtgta
    27001 taatcagagc ttgtgagtag tctaattaat tagataactc tccttgctct taggaaccta
    27061 agagccgaaa gtccacaggg aggtgaatat caatggaaaa cacgaaatat gaaatcatgt
    27121 acattattcg tccaaacatt gatgaagaag caaaaactgc tttaatcgaa cgtttcgatg
    27181 caatcttgaa agataacgga gcagaagtta tcgaatcaaa agattgggaa aaacgccgtt
    27241 tcgcttatga aatgaacggt taccgtgaag gtatctatca catcgttaaa gtatcttctc
    27301 catcatcagc aaatgctgtc aatgaatttg accgtcttgc taaaatcaac gacgatatca
    27361 ttcgtcacat gattgttaaa gaagaagctt aattgttgtt tcatgtgaaa caatagaaaa
    27421 cgatgagagg agatgactat tttgattaat aatgttgtat tagttggacg tctgacgaaa
    27481 gatccagatt tgcgttacac agcaagtggt acggcagtcg caacatttac tttggctgtg
    27541 aatcgtaatt ttacaaacca aagcggcaat cgcgaggctg attttatcaa ctgtgtgatt
    27601 tggcgcaaat cagcagaaac tttagcaaac tatgctcgta aaggaacact tttaggtgtt
    27661 actggacgta tccaaactcg ttcttatgat aatcagcaag gacaacgtgt atacgtgaca
    27721 gaagtagtag ctgacaactt ccaattgctg gaaagtcgtt ctgcatctga aaatcgccaa
    27781 caaagcggcg gattccaaag ttctggtcaa tcagctggcg gatttggcgg aaacaataac
    27841 tctaatcaaa catctcaatc atccaacggt atgcctgatt tcgaccgtga tacttctgac
    27901 ccattcggct caagttcaac gatcgacatt tcagacgatg atttaccatt ctaaacgaat
    27961 ttgataggag ggaaatagaa tggcacaaca aagaagaggc ggacgtaaac gtcgtaaagt
    28021 agactacatt gctgctaacc atattgaata tatcgattat aaagatatcg aattactaaa
    28081 aagatttatt tcagaacgcg gtaaaatctt gccacgtcgt gtaactggta caggcgctaa
    28141 aaaccaacgt aaaattactg ttgcaatcaa acgcgctcgt atcatgggct tgctaccttt
    28201 cgttagcgaa gactaataaa tcctaggaat tgaatgactg atccttttga tcagctattc
    28261 aattcctttt tttctgtaaa aataacctct attcgtttag tcgctcgaat gacgaaagtt
    28321 atggtaaaat caaattagtc atatatggga ggaaaattat ggaaaataaa aacaatcatt
    28381 tatccccgaa acctctcttc cttatcctgt ttatattaat cgaagtattg gtagtcttaa
    28441 ttttaccatt tcgttttgtt agcgcttcgg tcattctatt gatgaattta tggggtgttc
    28501 gctattggtt gaaaatgaaa cgttggctta ttttaaataa acgtgaaaaa atccagcagg
    28561 cttcgactgt agctgaaacc aatctagctt atgtctcaga agtcatgcct gtaggagtga
    28621 ttgcttatca gccatcaagc caaaaaatcg aatggctcaa tccattagca ttgaaaatca
    28681 aagatcaaag tggattaaca gaggaagaat tgctagatac tttttttact gcaaaagaaa
    28741 aaaagaaaaa ccaagtctat ctagcagata aaacatttca gtttgatatg gatacagtaa
    28801 agggtgttgt ttattttaat gatattaccc aaaaccagtt gttaaaactc catcagacga
    28861 acagtcagcc ggtgattggt attttatcta ttgataacta tgcagatgcc attgataaat
    28921 tggatgacaa agagatttct tatttgaact ctttcgtcac tacactagtt tctgactgga
    28981 tgaatgaata ccatgtcttt ttcaaaagaa tcaacgcaga acggtttttc ttcgtagcac
    29041 agatgatcga tctgaaaaag atgatggata aaaaatttga tttgctggat cgctttcgag
    29101 cagaagctga aaaacagagc tcgcctatca cccttagtat ggggattgct tatggctcaa
    29161 gaaccctcga tgaaatcggt ggagaagctc agaataattt agatgttgct ttagtccgtg
    29221 gaggcgacca agttgtcgtg aaagaggtaa aagaaggagc aaaacctgtt tattatgggg
    29281 ggaaatctgc taagaatgtc aaacgcacgc gtgttcgttc tcgagcgatg agtaccgctt
    29341 tgcgtcggat ttttgatgaa acaggcgatg tgtttatcat ggggcacaag tttccggata
    29401 tggatgcttt aggctctgct tttggtgtca gttgtctggc acgcttcaac cagaaaaaag
    29461 cttacatcgt tatcaacgag aacgagatca ttccagatgt agaacggtgt cttgaagaaa
    29521 tccataagca tcctgaatta gaaatgcaac taatctctcc agaacgtgcc atagagctga
    29581 aaaaagaaga ggacctcctc gtgatggtgg attaccataa accttctcta tcgatctctc
    29641 agggcctata tgagcaattt gataagattg tgatcattga tcaccatcgt cgtggggaag
    29701 agtttccaag taaacctctg ctgacttata tcgaatcttc agcttcttca gcttcagagc
    29761 tagtttctga gctgatccaa taccaaagca gcaaaacaaa tcgcttagat cgttttgagg
    29821 ccacattatt gcttgcaggg atggttgtag atacaaatag tttcaatgtc cgtacaactg
    29881 cacgaacttt tgacgttgcc agctatttaa ggtcttgtgg agcagacgca tccttagtac
    29941 aatatttatt gagctcggat ttagcgacat acttggagat cagcaatttg attgctggaa
    30001 gcgactatgt gacttctgat attgttgtgg cggcagggac agacgaaaaa gagtataata
    30061 gtgttatagc agcaaaaaca gcagatacat tgctttcgat gatcaatatc aatgcagctt
    30121 tcgtcattac aaagcggaca gacggcttga ttgggatcag tgccagaagt accggcacga
    30181 tcaacgtcca aatcatcatg gaatccttag gtggcggagg acacttcaca aacgcagcta
    30241 ctcaactgga aaatacgaca gttgaggaaa caaaacagaa gctatttgct gcaatcaaag
    30301 aaaatatgaa tcaaatatat gataaggagt aatccaaatg aaagtaattt ttttacaaga
    30361 tgtaaaagga aaaggtaaaa aaggggacat caaagaagtt ccagcaggtt atgcacaaaa
    30421 ttatctaatc aaaaataact tggcaaaaga agcaacgaaa agcagtatca gtcagttagc
    30481 aggacaaaag aaagcacaag aaaaacacga agctgaaatc ttggaagaag ctaaaaagtt
    30541 aaaagaattc ttggaaaaag aagatactgt agtcgaattg aaggcgaaag caggggaaga
    30601 cagccgtttg tttggttcga tcccttcaaa acaaattgct gaagggttaa acaaacaata
    30661 caaaatcaaa ttagataaac gaaaaatcga attagaaaat ccgatccgtt cactaggcta
    30721 cacaaacgta cctgttaagc ttcatcatga ggtgacggct acgatcaaag ttcatgtcgt
    30781 acaagaataa caaatcttga tagcgatgtt cagctggtaa gtataaccag aaggaaaaaa
    30841 gacaaaccga aatttatctg agaaaacagc tgcagcaatg aaagcaaaag ctgcaaatcg
    30901 atttcagatt gatttcggtt tcttttttgg gaacagcaaa atagcataaa gaaaacgagt
    30961 ataataaaag agaactattt ttttattaca ctttcggtac gaatgatgac ttttctctca
    31021 ttttcttgta aaatgaagca attgaagaca aggagcgata cgtatgaatg aagtgtggca
    31081 ggatcgaatc ccaccgcaaa atattgaagc tgaacaagcg gttttaggct ctgtttttct
    31141 tgacgcagaa acgatcattg atgccatgga gtacatagag ccaaaagact tttatcgtcg
    31201 tggccatcaa attatttttg agacaatgat cgagttaaat gatcgtaatg aagcgattga
    31261 cgtggttact gtcaaagacc ggctggaaca agccaatttg ttagaagatg ccggtggttt
    31321 aagttatctc tcagacttgg cattagcagt tccgacagca gcaaatatcg tctactatgc
    31381 gaaaatcgtt gaagaaaaat cattgctgcg tacattgatc cagacagcaa caggaatcgt
    31441 tacgaaagga ttcgagcaag gagaagaagt tcaaacaatt ttagatgatg ccgaacgcag
    31501 tatcttggag gtttcggaaa aaagaaatcg aagcggcttt ttatctattg ctgaagtact
    31561 gaactccacg attgaaaata tcgatcgact agctcaaaac aatgaagaaa tcacaggtct
    31621 accaactggc tatcaaggtc tggataaaat gacagcaggt ttccagcccg aagaactaat
    31681 cattcttgct gcacgtccag cggtaggtaa aacagcgttt gcattgaata ttgctcaaaa
    31741 tgtaggaaca aaaacagatc gttctgttgc gatatttagt ttggaaatgg gggcagaatc
    31801 tcttgtaaat cggatgcttt gtgcagaagg ttcgattgag gccagccatt tacgtacagg
    31861 tcagctttcg gaagaagaat ggtcgaatct gatcgttgcg atggggagtc tttctcgagc
    31921 aaatattttt atcgatgata caccagggat caaaatctct gaaatccgtg cgaaatgtcg
    31981 gaaactagcg caagaaaaag gcaatctagg cttgatattg atcgattatt tgcagttgat
    32041 tgaaggtaac ggtaaagaga accgtcaaca agaagtatca gatatctctc gccaactgaa
    32101 aaaactggcg aaagagctga aagtacctgt cattgctctt tcacagttat ctcgtggagt
    32161 agaacagcga caagacaaac gaccagtgct aagtgatatt cgtgaatccg gatcaattga
    32221 acaagatgcg gacatcgtag ccttcttgta tcgagatgat tattatgaaa gagaaggcgg
    32281 agatgacgat gatggaaacg agccaaaaaa tgacaacgtc atcgaagtca tcatcgagaa
    32341 gaaccgaagc ggtgcacgag gaacagttga actactgttt atcaaagaat acaataagtt
    32401 ttcgtcgctt tcgccaagag aagaatttta aagaagaggt tgtgagcctt gagcaatccc
    32461 gagagctctc gtaagaagat gcaaggagta accgcaggaa cgactagagt acttaattta
    32521 aacagatctc caaagggatt gtgacaaaag tcttgtcaca gtcccttttt ccgaataaac
    32581 ggtgttcaat cagctgaccc ttggtattag ctcagcaaac gtcaaaatat gaggaactat
    32641 tttgacgttt gtttctctaa tactcaggtc aaaacgctga tcttacgacc tcttttcctt
    32701 aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatcatcaa acatgagaag
    32761 cagttttttg aaattgctcc ttgtgactca gagttaaacg gcaggctcac aacctctttc
    32821 ttaaacggtg ttcaaaagct tgcatctgcg gtaatacgcc caatcaaacg aaaaatatga
    32881 gaagctattt ttgtttggct gttcttatta cttgatgcag gacagctttt tcacaacctc
    32941 tgattcacgg tgttccaaaa gtagcttctt cgaaaaataa gtcgaaattt cacaaaaatt
    33001 tgagaagcaa ttttcgtaca ttccttctta tttcttgaag ctgaccactt ctgttacaac
    33061 ctctttttta ataaccattc taaaaagata aagttcgttt tttaagcgtt tttataaaat
    33121 aaaaataaaa atcattcgat tttatttgaa atatgtatct attattgata caatggttca
    33181 ggattaaata atatagaacg aggtgttcac atgtcatctg tagtagtagt aggtacgcaa
    33241 tggggcgatg aagggaaagg aaaaatcaca gactttctca gtgaaaatgc tgaagtgatt
    33301 gcacggtacc aaggtggcga caatgcaggg cacacaatta agtttaacgg tgtgacttat
    33361 aaactgcatt tgattccttc tgggattttt tataaagaca agatcagtgt gatcggaaac
    33421 ggcgttgtag tcaatcctaa atcattggtt aaagaattag cttatttaca tgaaaaaggt
    33481 gtagaaacaa gtaatttgcg tatttctgac cgcgcgcacg taatcttgcc ttatcatatc
    33541 aaattggacc aattacaaga agatgctaag ggcgaaaata agattggtac aacgattaaa
    33601 ggaatcggac ctgcctatat ggataaagca gctcgtgtag gtatccgtat tgcagactta
    33661 ttagataaag aaatttttga agaacgtctt cgtttgaatc tagatgacaa aaaccgtcaa
    33721 tttgtaaaaa tgtttgattc agaaccactt gattttgacg atatttttga agaatattat
    33781 gaatacggac aacaaatcaa acaatacgtc acagatactt ccgttatctt gaatgatgct
    33841 ttggatgcag gcaaacgcgt gttgtttgaa ggcgcacaag gtgtaatgct ggatatcgac
    33901 cagggaactt atccttttgt tacttcttct aacccagtag ccggtggggt aacaatcgga
    33961 agcggtgtag ggccttcaaa aatcaataaa gttgtcggcg tctgcaaagc ctatacgtca
    34021 cgtgtcggtg atggaccatt tccaactgaa ttatttgatg aaacaggaga acaaatccgc
    34081 gaagtaggac gagaatacgg tacgacaact ggtcgtccgc gtcgtgtagg ctggtttgat
    34141 tctgtagtta tgcgccattc taaacgagtt tcaggtatta ccaacctatc tttaaactcg
    34201 atcgatgtat taagtggatt ggaaacagta aaaatttgta cggcttatga attagatggc
    34261 gaactaatct accactatcc agcaagcttg aaagagttga accgctgcaa accaatctat
    34321 gaagaattgc caggctggtc agaagacatt acaggatgca aaacacttgc agaactgcca
    34381 gaaaacgcac gtaactatgt acgtcgtatc tcagagcttg ttggtgtacg tatctcaaca
    34441 ttttctgtcg gacctgatag aacacaaaca aacatcttag aaagcgtctg ggcgcaaatc
    34501 taaggataaa aacgacgact gaatcaggac gttcttacca gagcgagtcg aagtgtttat
    34561 ctatacgata ataataactt gaacactgtt tattcagaat aagggactgt gacaaaaacc
    34621 gtgtcacagt ccctttttcc gaa
//
LOCUS       DACGMI010000032        33841 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.033, whole genome shotgun sequence.
ACCESSION   DACGMI010000032 DACGMI010000000
VERSION     DACGMI010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33841
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.033"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..1390)
                     /locus_tag="IXT46_001630"
     CDS             complement(<1..1390)
                     /locus_tag="IXT46_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017434062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4947547.1"
                     /translation="MSNKEEAKSIINFVGGKENIAALTHCVTRLRFALRDDTKVDKAG
                     LENLEDVKGTFNANGQFQVVIGPKVADIYEEVISQSGLSGANKEDVKKVAAELNLNWF
                     QRAVKILGDVFVPILPAIVTAGLLMGLNNLLTNPGIFFEQSLIEVYPNIADVADMINL
                     IANTSFQFLPALITWSTVKYFKGNPLLGIVLGLVFVHPDLMNAWNYGQAVTTGDIPHW
                     TIFGLSISKIGLQAQVLPALVSGYVLAKTELFLKKRVPETIQLLVVAPVAILFTSVIT
                     FIIIAPITIAIGNTIVAGIVWLFQKVPFIGGFAYGIGLAPLVVTGMHHAFLPVHIQLM
                     ANGGDYIWPIGVMSSLAQGSAAIAMNFLIQNKKLKGVGLAAGLSAYMGITEPAMFGVN
                     LKYKFPFVVSILTSGIIGGFMASQHVIATSVGISGIPGFLSIPFEFWPIFFICMLASC
                     VVSFGATYLYGKN"
     gene            complement(1383..1685)
                     /locus_tag="IXT46_001631"
     CDS             complement(1383..1685)
                     /locus_tag="IXT46_001631"
                     /inference="COORDINATES: protein motif:HMM:NF025668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947548.1"
                     /translation="MTTTVSNKGSRDGYEVVQLYIGAQYGRYIRPTKDLVAYKKVFVK
                     SGDSVTVSFELTNKDFKYYDEEFNEIIDDGAYWIMVGNDSSQALTNKEEIEVRINE"
     gene            complement(1743..1994)
                     /locus_tag="IXT46_001632"
                     /pseudo
     CDS             complement(1743..1994)
                     /locus_tag="IXT46_001632"
                     /inference="COORDINATES: protein motif:HMM:NF014026.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
     gene            complement(2838..5987)
                     /locus_tag="IXT46_001633"
     CDS             complement(2838..5987)
                     /locus_tag="IXT46_001633"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HAQ4947549.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGEIGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLAIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PDKTKGLIVTFRKPATMEKNVEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(6000..7217)
                     /locus_tag="IXT46_001634"
     CDS             complement(6000..7217)
                     /locus_tag="IXT46_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAQ4947550.1"
                     /translation="MSNDTQPEIRFPGFTDDWEQRKLGDFVVDYVEKTSVQNQFPMLT
                     SSQQKGIVLQEDYFANRQVTTENNIGYFVLPRGYFTFRSRSDNDVFVFNRNDIIDRGI
                     ISYFYPVFTLKSADSDFFLRRINNGIQRQLSIQAEGTGQHVLSLKKFKNIVAMFPSEE
                     EQQKIGTFFKQLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWE
                     ERKLGELGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIER
                     KKWKPIKDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFE
                     TINLPRYSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLL
                     KETKKSFLQKMFV"
     gene            complement(7207..8802)
                     /locus_tag="IXT46_001635"
     CDS             complement(7207..8802)
                     /locus_tag="IXT46_001635"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAQ4947551.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKKLLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            complement(9312..10094)
                     /locus_tag="IXT46_001636"
     CDS             complement(9312..10094)
                     /locus_tag="IXT46_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947552.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(10159..10995)
                     /locus_tag="IXT46_001637"
     CDS             complement(10159..10995)
                     /locus_tag="IXT46_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4947553.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(11013..12422)
                     /locus_tag="IXT46_001638"
     CDS             complement(11013..12422)
                     /locus_tag="IXT46_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4947554.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(12436..14259)
                     /locus_tag="IXT46_001639"
     CDS             complement(12436..14259)
                     /locus_tag="IXT46_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4947555.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(15102..15428)
                     /locus_tag="IXT46_001640"
     CDS             complement(15102..15428)
                     /locus_tag="IXT46_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947556.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(15474..15836)
                     /locus_tag="IXT46_001641"
     CDS             complement(15474..15836)
                     /locus_tag="IXT46_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAQ4947557.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(15873..16088)
                     /locus_tag="IXT46_001642"
     CDS             complement(15873..16088)
                     /locus_tag="IXT46_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4947558.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            16215..16550
                     /locus_tag="IXT46_001643"
     CDS             16215..16550
                     /locus_tag="IXT46_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4947559.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(16626..18623)
                     /locus_tag="IXT46_001644"
     CDS             complement(16626..18623)
                     /locus_tag="IXT46_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947560.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSVEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(18721..18996)
                     /locus_tag="IXT46_001645"
     CDS             complement(18721..18996)
                     /locus_tag="IXT46_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4947561.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            19228..19962
                     /locus_tag="IXT46_001646"
     CDS             19228..19962
                     /locus_tag="IXT46_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4947562.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEKFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            20001..21143
                     /locus_tag="IXT46_001647"
     CDS             20001..21143
                     /locus_tag="IXT46_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4947563.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(21238..22629)
                     /gene="sufB"
                     /locus_tag="IXT46_001648"
     CDS             complement(21238..22629)
                     /gene="sufB"
                     /locus_tag="IXT46_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAQ4947564.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKAVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(22634..23104)
                     /locus_tag="IXT46_001649"
     CDS             complement(22634..23104)
                     /locus_tag="IXT46_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAQ4947565.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(23091..24326)
                     /locus_tag="IXT46_001650"
     CDS             complement(23091..24326)
                     /locus_tag="IXT46_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAQ4947566.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(24323..25609)
                     /gene="sufD"
                     /locus_tag="IXT46_001651"
     CDS             complement(24323..25609)
                     /gene="sufD"
                     /locus_tag="IXT46_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAQ4947567.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(25622..26395)
                     /gene="sufC"
                     /locus_tag="IXT46_001652"
     CDS             complement(25622..26395)
                     /gene="sufC"
                     /locus_tag="IXT46_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAQ4947568.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(26592..27440)
                     /locus_tag="IXT46_001653"
     CDS             complement(26592..27440)
                     /locus_tag="IXT46_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4947569.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(27464..28150)
                     /locus_tag="IXT46_001654"
     CDS             complement(27464..28150)
                     /locus_tag="IXT46_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4947570.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(28143..29177)
                     /locus_tag="IXT46_001655"
     CDS             complement(28143..29177)
                     /locus_tag="IXT46_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4947571.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            complement(29572..29910)
                     /locus_tag="IXT46_001656"
     CDS             complement(29572..29910)
                     /locus_tag="IXT46_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAQ4947572.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(29912..30268)
                     /locus_tag="IXT46_001657"
     CDS             complement(29912..30268)
                     /locus_tag="IXT46_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAQ4947573.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(30274..31461)
                     /locus_tag="IXT46_001658"
     CDS             complement(30274..31461)
                     /locus_tag="IXT46_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAQ4947574.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(31652..32497)
                     /locus_tag="IXT46_001659"
     CDS             complement(31652..32497)
                     /locus_tag="IXT46_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4947575.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            32731..33696
                     /locus_tag="IXT46_001660"
     CDS             32731..33696
                     /locus_tag="IXT46_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAQ4947576.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
BASE COUNT         9907 a         7082 c         5675 g        11177 t
ORIGIN      
        1 tatttttccc gtaaaggtaa gttgctccaa atgagacgac acaacttgct agcatacaaa
       61 taaagaatat tggccagaat tcaaacggaa tagacaagaa accaggaatt ccactgatac
      121 caacagaagt tgcaatgacg tgttgtgacg ccataaatcc tccaattatt ccagaggtca
      181 gaatggaaac cacgaatggg aatttatact ttagattaac cccgaacatt gctggctcag
      241 tgatacccat ataagcagac aaaccggcag ccagtccaac acctttcaac tttttatttt
      301 ggattaagaa attcattgca atagcagcag aaccttgtgc caaacttgac atgactccaa
      361 taggccaaat ataatctcca ccgttcgcca tcaattgaat atgaactggt aaaaacgcat
      421 gatgcatccc tgtcacgact aatggcgcaa gaccaatacc ataagcaaat ccgccaataa
      481 atggaacttt ttggaataac catacaatac ctgcgacaat cgtattacca atagcaattg
      541 taatcggcgc tataataata aatgttataa cactagtaaa aagaattgca actggtgcaa
      601 caaccaacag ttggattgtt tcaggcacac gctttttcaa gaatagctct gttttagcta
      661 acacatagcc ggaaactaga gctggcaata cttgtgcttg tagtcctatc ttagagatgg
      721 acaatccaaa gattgtccaa tgtggaatat ctcccgtggt tactgcttgc ccgtaattcc
      781 aggcattcat caaatctggg tgtacaaaga ctagacctaa cacaatccca agaagaggat
      841 ttcctttaaa gtattttaca gttgaccatg ttattaacgc aggcagaaat tgaaaggaag
      901 tgtttgcgat aagatttatc atatcagcga catcagcaat attaggatat acttcaatga
      961 gtgactgctc aaaaaagatt cctgggtttg ttaataaatt attcagtccc atcagtaaac
     1021 cagctgtaac gatcgctggt aaaatcggca caaatacatc acccaatatt ttaactgcac
     1081 gttgaaacca attcaaattc aactcagccg ctactttttt aacgtcttct ttgtttgccc
     1141 cactcagccc agattggctt ataacctctt catagatatc tgctacttta ggaccgataa
     1201 caacttgaaa ctgtccatta gcattgaagg tacccttcac atcttccagg ttttccaatc
     1261 ctgccttatc aactttagtg tcatctcgca aggcaaacct cagacgtgtc acacagtgag
     1321 tcagtgctgc aatattctct tttccaccaa caaagttaat gattgattta gcttcttctt
     1381 tattactcat taattcttac ctctatttct tctttattag ttaatgcttg agatgaatca
     1441 ttgcctacca tgatccaata agcaccatca tctataattt cgttgaactc ttcatcataa
     1501 tacttaaaat ctttgtttgt aagttcaaaa gaaacagtca cactatcccc tgacttaaca
     1561 aaaaccttct tgtaggctac caagtctttt gttggtctta tataacgacc atattgagct
     1621 ccaatatata gttgaacaac ctcataacca tctctacttc ctttatttga aacggtagta
     1681 gtcaccttca aacagttctt acccttctct ttaatgctaa ttggtgacat agaaaaagtg
     1741 gtataactca acccataccc aaagggaaat tgtggttcat tggatacatc taagtatttg
     1801 gtcgtattaa acttttcact tgaatacggt ctaccagtat tgaaataatt ataataaata
     1861 gggatttgtc ctaaatgtct cggaattgtt attgtaagct ttccggctgg gtttattttg
     1921 ccacaaagga cgtccaaaat agcattgcca gcctctgctc ctagatgcca agcctcaact
     1981 aatcccttac atatagattt ttaaattaca cactagttta aactaaaaca aacaaggaaa
     2041 aacttaccat ttaatcaaaa aattagctca tatgaatata ttagaatgta aattagactg
     2101 gtcaaaatct ggtcaaaaaa gaggacgaat acaggtagtc ctcttttttg ttattttgat
     2161 attctaaatc attttttatt ggattattcc cttgttcgat atagacccaa attgatctat
     2221 caataattat caaactgagt catatagaga caaaaatttc aaaaatgacc tgttaaatgg
     2281 tcatcgaata tcatttaaaa tcaatacgac ggagtcagac acggagtcaa aacaagcccg
     2341 ctgagagtaa aaaatataca gtcccatagg taaagtgcca caggactgta tattttttta
     2401 tttgagatta cctgaaatga ttccatttaa tttttatctc attttttcct actagttagt
     2461 atcaaatact ctcctatttt ctcaataaac tattttgggt tacatggtat ctgaaacagc
     2521 taaaaccttg tcattatagc aaaaaatcac tttatctccg tttcatttca gatacatttc
     2581 acttaagcgg attccaaaaa aacaaaagaa aaaggaaccc ctagttagcc tatgcttttt
     2641 attggttcct ctcaaaacac ggtcatataa caacggggtg gggtaaatga atgaaaaagg
     2701 tggaggaaac attattcaat agctgtctta aatacttcgt tataaaatgt gaacaaataa
     2761 aagacatcta tccctatttt ctacacttcc acttgactac catctttgaa tcgtacaatt
     2821 ttcttaactc ttctcgttta cctcaattca ttctcaagtg gaatcaactc atcatctaac
     2881 attttacgcc atgctcgctt catttcttgt gggtatttaa atggcttcgc ttctggatgt
     2941 ttggctttat atccttcgta atccttactg ttgataattg ctttcatatt aggaattgga
     3001 tcttcacctg gtagatattg cagattagaa gcatgtaatt ctttctcaga aacaaaccac
     3061 tcattggaaa agacatgaat caaatcatca ctcgcttgtg taaaatagcg acgtttaatg
     3121 acaaagatat cttcattact atctaaagtc cccacatcaa atgcatttaa aatttgtcgg
     3181 taaacttctt tgactccttc tgttttattc aatttagcca aagctttttc aatttcttct
     3241 cgtgcatctg aactattcgc agcataagtt cctagtaatt gatcaatata agttgaatca
     3301 atatcataca acttagtggt attttcacta taaaattcga tcgttgaaaa atcttctcct
     3361 tctttttctg gttcttcctc tattaatgaa cccttcacgg tctcgtacac gccaatttgt
     3421 tcttccaaaa gttgaatttg attgttcaaa gttggagatt tcaccatgtc atcattgtaa
     3481 tcgtcataag tcactaacga ttcataagca cgattcaatt cttgaaatgc tttgacgtac
     3541 tcgatacgga tttcaagtgg cgtatgttca tcaatggatt ccatggatga aacctctttt
     3601 aacttaccat atgcttgttt gaatcttttt ttggattcct gataacttgg ataaatcaaa
     3661 cctgattctt cttttgcttt tgaatacagt tttgtcgcat cctcgacatt cttctccatt
     3721 gtcgctggct tacgaaacgt cacaatcaat ccttttgtct tatcaggata cgtacgattc
     3781 gtacgtgaaa aagcttggat caatcctgca tactctagat tacgatccac aaatagggtt
     3841 tgaatcgtag gggcgtcaaa acctgttaat agacgatcca ctacaatcgc taaatcgatt
     3901 tgtttcccaa attgtttgaa ttccgctctt tttcgtgcca aacgattatt gatgtctccg
     3961 ttataacgct caatgtctgc taatgaccag gaagtatcat aatactgatt atattcctca
     4021 ataatttttt gcatttcttc ttgttgggca cttgaatctc ggctattttc ttctaatgaa
     4081 taggtaatag cgattcgtgg aaaatcagga tcctccatcg ttcgtccttc acgaatgagc
     4141 tgattgggaa actcttttgt taaccaatca ggctctttcg tcatctcttt gatggcccga
     4201 taatactttt tggccatgtc aatggaactc gtggttaaga ttgcagattt cgttggcctg
     4261 ccatttcgaa aatcaaattt tgtataggca ttatctggac ggaacatttt atgaatgact
     4321 ttttggatat gttcatctgc ttcaaaaaca gctgggtcca aataactttc ttttttgaca
     4381 ggttccattt gatcaatcat acgattgatc tgttctgatg aatactctgc atatgtttct
     4441 acttctttta atttccgata gattttattc tctagtgaag tcggctccac ggtgttttca
     4501 tgctctactt gaaatcctaa gacagagcca tcttctagcg cattcttaat ggtataggta
     4561 tgcaagacct ctccatactg atcatgggtt gtacgtgcca attgcccttt ggcttgtttc
     4621 cgattctcag gaaaaatcgg tgtacctgta aagccaaacc aagtggattt cggaaacatt
     4681 tttttgattt cttccatatt ttcagcactt aacgctcgat gacactcatc tactacaaac
     4741 acgatatgtt ggcccattaa tttttggaag cgattggttc cttttttctc ttcttgtttc
     4801 tttgcatatt tcaacgccgc atctagtttt tgacgggttg taatgattac aacatttgca
     4861 ttggcatctg ccaacagggt ttcacttaat tctttggcac ttcccgttcc aacgatcaag
     4921 ctattcgctt tggcgttccc ggaagaaatc ccagtattaa attccgaagc aaattttgta
     4981 aactctgtgg tggtttgatt atctaaatct ttgcggtcca ctaacatgat cgttcgatcg
     5041 atccccgatt ttcgtgctaa aagcttagta gatacaaaac tagtcaacgt ctttcctgaa
     5101 ccagtcgcat gccacacata ccctgattga tgtttatttg cggcaataaa caaggcttga
     5161 atcgcatgta cttgataagg atgtaacacc atgagggttt tattgtcttg atcttcactg
     5221 acgattgtat aatccgcaat caaacgatga gcatccggga tatttaacac ttgtttacaa
     5281 aactcatata agttttctac tttttcattg tctttcgttc gccaactaaa taaaaactta
     5341 gggtgcaagt ctttcggtaa ggcatttgca aaataccgag tggtttgttc attggaaacc
     5401 acaaacaact gtaaggtcga aaagatattg ttccgaaaca taccttcttc tgcatatttt
     5461 ttgatttggt taaatgcctg ataaacacca tcttttgcag ttacttgttt cagctcgatt
     5521 tggacaatcg gtaatccatt gattaataag gtgacgtcaa aacgtcgatc ccgtgcttct
     5581 atgttacttc cacgttttgc aatttgatgg accacttcat aagtagagat tcctccacca
     5641 atgtcttgat tggaataaag gataagtgag acagaaccca attgcgaatc ttcccgttca
     5701 atcgtgatcc gagccatccc aatttcacct tttaaccatt tcgcagcatc aaatggggtt
     5761 ttcgttcgca gcagtaattc cgttttgatc gtttcaaatt ctttatcggt caaaggaaaa
     5821 tcattcagtt ctgcttgatt atttgagata attttttggc gtaaattgac ccaaaggtct
     5881 tcttctgatt ttagatccgg acgatacgtc cactgattat gcccttctcc aagtacacga
     5941 atcaactgtt cttcgacttc tgcttcctca cggtgactaa ttttcattct tcttccctcc
     6001 tagacaaaca tcttttgtaa gaagcttttt ttcgtttctt ttagtaaatc taacttacgt
     6061 tgatgaagag cgatcgtatc atctagctgt ttgaagaaag taccgatttt ttgttgttca
     6121 tcctttacag gaaccttaac actgatattc tcaatatcag aactgttata agaaggcaat
     6181 gcccctactt gggagtatct tggcaaattt atagtttcaa acaatatttt accaaaatag
     6241 atatcccaag tattattaaa taaataagcc atggtattgt tatctattaa gaaagggctt
     6301 gtgaccaaac gttttctatt aagcattatt gctgcgccaa ctttagcaaa tataatcgct
     6361 ggcacatctt ttattggctt ccatttttta cgctcaattt gctcattaga tacataatga
     6421 tttgcatttc tcatttcata ctcattacca atgttattca tgtcggaaac tttaaaaaat
     6481 ggagtacctt cagaaccacc ttgctcggca tcaggaaatc caattcccga ttgagtttta
     6541 cctaattctc ccaacttacg ctcttcccaa tcttccgtaa aaccaggaaa ccggatttct
     6601 ggcacttttg ctccgttttc agggaacatt ttttgtaaga atcctttttt cgtttccttc
     6661 agcaaatcta acttacgctg atgaagagcg atcgtgtcgt caagttgttt gaagaaggtg
     6721 ccgatttttt gttgttcttc ctcactagga aacattgcta ctatattttt aaactttttt
     6781 agagacagaa catgttgacc tgttccctct gcttgaatag ataattgtcg ttggattcca
     6841 ttgttaatac gtcttaagaa gaagtcggaa tcagcagatt ttaaagtaaa tacaggataa
     6901 aaatagctta taatccctct atcaataatg tcattacggt taaacacaaa cacatcatta
     6961 tcacttcgac tacggaacgt gaaatatcct ctaggtagta caaagtaacc aatattattt
     7021 tctgtagtta cttgccgatt tgcaaaatag tcttcttgca aaactatccc tttttgttga
     7081 gatgaagtta gcataggaaa ttgattttgt acacttgtct tttcaacata atctacaacg
     7141 aagtccccca acttcctctg ttcccaatca tctgtaaatc ctgggaaacg gatttctggt
     7201 tgtgtatcat tgctcatgtt tgaacacctc cagcgcacct tgtaaccacg cttcattttc
     7261 aggtgttgtt tgcagggaag agatagcttc taaaagtttt ttttctagca cttgctgttc
     7321 ttgtcgtatc ttcttgatgt catttccgac atgaaccata tcaattggtt cttcttcttc
     7381 gaaagtatct acatagcgtg ggatatttaa gttatagtca ttttctttga tttcatcaaa
     7441 ggttgccaaa tgagcgtatt tctcgacatc ttttctttca gcgtaggttt cgaggatttt
     7501 ttgaatgttt tcttccgata gtttattttg atttttccct ttaacaaatt cacgactagc
     7561 atcaatgaat aatacatctc gagtttgacg attcttcttc aacacaatca ccgtcgttgg
     7621 aatcgatgtc ccaaagaaca agttcgcagg cataccgatc acagcataaa tactgccatc
     7681 ttctagtaat ttttgacgga tgaccccttc tgcagcgcca cggaataaaa ctccgtgtgg
     7741 taagacgatg gccatggtac ctgtttcctt caaatgatag aacccatgaa gaagaaacgc
     7801 aaaatctgct ttggattttg gcgctaattt cccataacga ttaaaccgag aatcatctaa
     7861 gaaagtcgta tctgctgacc aattagccga ataaggtggg ttcattacta ctgcatcaaa
     7921 tgtgtaaggt tcatctgttg gccagtcctt attcaacgta tccccattgc ggagattcat
     7981 ttcttcggcg tcgacaccat gtaaaatcaa gttcattttt gctagattgt atgtcgttgt
     8041 atttagttct tgcccatgat atttaacgtt atctgggtgt gttaagtagt tacgtacgtt
     8101 taacatcaat gaacctgaac ccatcgttgg atcaaaaaca ctaaagaatc gtcgttcctt
     8161 ttgatcgagc gttacgattt gcgccatcat atcagaaacc atatgaggtg tgtaaaattc
     8221 tccggctttc ttccctgctt ctgaagcaaa ttgactgatc agaaactcat acgcatcccc
     8281 gatcacgtcc ccatcgtgtt ctaaaacatc tacatcattc aatttcttga tgacttcggt
     8341 aatcgtcaca tttcgttgtt gctcatctgt tcctagtttt tttgattgga gatccacatc
     8401 atcaaataac ccattaaatt gattgtaggt agatgccaat tgcacaaagg ctttgtttag
     8461 atcgttcaat tggaacgttg cttgttttgc ttgatccgct aagacgttga aaagatactc
     8521 tggtgcaatt gcatatccca aaatatcaac gattgtggca atcagatctt cttttgattc
     8581 ttcatctgaa agtaattcac gatacaacat tgtttgtttg cttactgtgt catattcctc
     8641 taaggattca tctgctaaaa gaaccacttg ttccaacaat cgatcggata aatatttata
     8701 gaaaatcagt cccaataaat aatttttata ttctgacgca tccattttac tacggagatt
     8761 atctgccgca ctaaataatt tttgatttaa ttctgcaccc aaaaagatac actcctatct
     8821 cttatttaaa gttgctatat accctcttat tttagcatac ccccttttat aaaaagcaaa
     8881 aaaaaaaaga aagaaactta ttcttgctaa taaactacgc gaaaggagtc taacgttgtt
     8941 tgatataact tagactgatc gttaacttat tttttatatt tctacatagt tatctttaga
     9001 accatttcag atacatatga aacaattaca tatgattttt tcataaaaaa acagtactgt
     9061 ctagtagtat aaaatataca aatttcttaa aaattttttc actaaaatca ctacctgaaa
     9121 cagtctaaaa cacttatata tcaacgttta atgaaactat ctccgtttca tttcagatac
     9181 aaataaatat agtcgggctc caaatccgaa aaaaaatacc cccagtagct tatcctaagc
     9241 tactggagat gtataagtac ggtcatataa caacggggta gggtaaataa atgaaaaaga
     9301 tggaagaatc attattcaat aactttttta aatacttcgt tgtaatcagt tacctgtccg
     9361 ttcttaaata ccacagaata atcttttttc ccattttcaa gtaaccgaag tggaatgtct
     9421 ttaccaactt gctctgtcac tgcattactg atacctgtta gattagctaa taaatctgat
     9481 aaagattgag catctgtaga aatctctgta tcagtattta tcgtgattcc tttatcttca
     9541 tttacaagct tccaagtagg tggtatagct gtgtatgttt cgatgaatga atcaattctt
     9601 tcatctatcg tcttcccagt atctacttct gtctcattac tcttagatga atcgattctt
     9661 tcatccatcg tctgctccgt aactgcttct gtctcattat tctcaccgga aactctcttc
     9721 acacccaaac ttatatattg tccatcttta gtgtgcatag ttaaaattcc cacgctttta
     9781 ctaataaatt cactataacc agttctttca atagagactt caatgtattt cacactatca
     9841 tactcaaaag aaaaatagac atgtaaaagc attttgttgt ttacatctac ataataatcc
     9901 tttgactcta cttgagacct tcctatacgg aatacagctt tactgtctga tatctctata
     9961 ccagcatcct tattattaat ctgccaatct ccaagtagct cttctggcaa gctagtagtt
    10021 tcttgtgaac actttaccac ttcactggta gaggtcgaaa cattcacctc cgcactgtta
    10081 gaagaatttt ccaaggaatc aggagcctta gcacaaccaa caagtcttta tatattgtgc
    10141 agccgatatt ttcttcattc agtacaccct tgaaatatgc agtgttagat aaagcagttc
    10201 gtcctgattt gctgaggcac ccatctcttc ttgaacgtac tccttgattt tcaaggccgc
    10261 ccgatactct ttcggaaaac gctgcttcac tgaagccagc aaaaaatcat ccttctccgg
    10321 caactcttcc ttcttaatca ttcgggcaat aaaaaactgt aaatgcgtca caaatcttaa
    10381 gtaaagcatc gaatctttat caaccttttt ttcgggaaac agatatccta gcatagccaa
    10441 gatatccttt agtgctctta ccgagagcat ggtttcttcc atatttgctt gttcactttg
    10501 ggcatttaca atgtgaaacg caatgtttcc agcctcctct tctggcaact gaacattcat
    10561 ttttttgttg atcaattgga tagcatagca gccgatctca aattcttttg ggtaatactt
    10621 ttgaatttca atcagcaggc gattttgaaa aacaatgcct ttttgactgc gttcaatggc
    10681 atgcttcaag tgatcaacca aggtaaaaaa tagactttta ttcagcttaa agtcaaactt
    10741 ggcgttggca taatcgataa ttcgcttgac gcaaataatt agatcatccg gagcagcctc
    10801 aaacagttta atgtaatcct tttttagagc atcagaaagt gaatctaatt taaatacttt
    10861 ttggattttg tcagccggaa ccaaatcgcc tttctttagt tgaaatccaa tccctttccc
    10921 catcaaaatt acttctttgc cttgcttatc taagcaaaga attaaactgt tgtttaacgt
    10981 tttaattact ctcattagat tcaccgttct ctctaagcta agccatttct tgcgattact
    11041 ttttgatacc aaaagaagct ttcttttttt attcgtttta attctttaag attctcatcg
    11101 gttcggtcaa catatataaa accataacgc ttattgaagc cttgatgggt actaacaaca
    11161 tcaatcgctg accaaggtaa ataaccaaaa acatctacac catctgttaa agctgcttga
    11221 atagccagaa tatgtttggc tagataatca attcgatcct ggtcattaat tcgtctatct
    11281 tcctcaacta tgtcgggtgc cccatagcca ttttcagtaa ttaaaatagg taaatcatag
    11341 cgatcgtaca atttcctcaa tgttaatcgt agtccagtag ggtcaactac ccagccatat
    11401 ggcgttttat ctacataagg attttcagct gcccggtaga caccttcttc tcccaacatg
    11461 atctgttgat cccccgctct agcggaaaca tctgatccgt catttttgct ggcagcgatg
    11521 gtggcagttg aataataatt aatcgcaata aaatcgggtt taccggagga taaaattgcc
    11581 tgatcctctg cctcaatttt aggatataat ccacgatcat tcaaatagtt ttcaaacaaa
    11641 taattgtatt ttccccgaac tgctacatct aagaaagacc agcctctcaa tgtttcccaa
    11701 ttatgggctg caattgcatc ttctggactg gaggtagctt gatacatagc cgttaaattg
    11761 attgctggac cgatttttcc tttaagattc aactgatgat acaagtgaat tactctagct
    11821 tgagctaata aaacatggtg attaatttga aagagttctt tttttgaagg cagctctcca
    11881 cttggtggca aaccaatcgc tccaggatga aggatcatcg tgttttgctc attaattgtc
    11941 agccaatagt tcaccttgtc accatactca gtaagcaata cctgtacata gtccacaaaa
    12001 taatcgatag ttgctcgatt taaccaaccg ccctgctcct ctagaaaata aggtaaatcg
    12061 aaatggtaca tggtgacaat cggttcgatt ccctgattca ggcattcatc aattacttga
    12121 tgataaaaag aaattccctt ttgattggtt ttattatttt caatatccat aattcgcgtc
    12181 caagcgatgg aaaagcgaaa agcttttaag cctaattctt taaacagctg tatatcttct
    12241 ttatagtgat ggtaaaaatc cgaggcaact tcaaaattag ctaccccttc tgtatgctga
    12301 tacttgtcaa taatagacgg ttgtttccca tcctcctgat aggcaccctc tgcctggtag
    12361 gcactaatgg aggcacccca taaaaacttc tctggaaatg ctgaaagctg tttgtattgc
    12421 acaaaaatcc tctccttaac taatttgcat caatggttcg tgttccttta agcttccgct
    12481 tgcttcacta attcctgcgt aattttcact gttggtcact accacaatca ctgtatcatc
    12541 gtagccagcg tttctaatgg cagcgaaatc ggcgttgatt aataattgtc ctgctgacac
    12601 ctgatctcct gcttttacaa atacttcaaa gggttcccct tttaaattca cggtgtcgat
    12661 ccccacatgg atcaataatt caataccttc tttagaacgt agaccaatcg catgtttaga
    12721 ttctaaaata gtaatgactt ctccctcaac aggtgaataa atgctgtttt cttctggatg
    12781 aatggctacg ccctttccca atagtccctt agaaaagaca gcatcgttca cttcagaaat
    12841 aggacacacg gttcctttta ccggattttc aacaatgact gcttcggcta ttgccgtttg
    12901 ctctgattca tcagaagtat cgtcaaatcc aattagataa gcaatgataa aggttgcaac
    12961 aaaggcgatt acacacgtaa taattgcgtg aacaatattc attggatttt ctccaataaa
    13021 ggctggtaag gctgctaagc caggggaaac aaaggcatat ctgactaaac cgctcaagcc
    13081 agcatacaaa ccagcaattg caccaccaat catggaagca actaatggtt ttttcagctt
    13141 caaggttact ccatagagtg aaggctcagt aattcccatt aaagcagtga tcccagtgga
    13201 cacagctagc tgcttcaact ctttgttttt agttttcgcg gctacagcaa aggtagcacc
    13261 tgattgagca atattagaag ccagcattcc tggcccattg atcatttcag aacccgtact
    13321 gctcaattgc atagtagcga ttggcgtcat tgcccaagct gtacccgtaa ccaccaaaaa
    13381 tggctgcaaa ccacccatca aaaatggaat taaccaagct gctttgccgt taatccattc
    13441 agcccccatt gctataagat cgttcagcaa cgttccaaac ggtccaatga caaccaacgc
    13501 taaaggcccc ataattaaaa ataccagcat cggcttagta aagaatttaa taaacgaagg
    13561 cgaaattcga tccgcaaagg gctctacata ggacatgatc caaacagtaa agataatcgg
    13621 taaaactgat cccgcataat ctgcagctaa taccggaatt cctagaaaag aaacggcatc
    13681 gccagtagaa aaaagctgtg aaatatttgg atgaagcaaa atgccagcaa cagtaatcgc
    13741 caaaattggg ttgacatcaa actttatggc tgccccatag gctaatagta ctggcataaa
    13801 ataaaaggct gcatcagcaa tagtattcaa aatgatgtaa gtttgactac tgtctgatag
    13861 tacaccagtc aaagtcaaga cggccaaaat ggcttttacc atcccggcac ctgttatagc
    13921 tggaatcatc ggtgtaaagg tggtagaaat gacactaatc aatcttgaaa taatactttc
    13981 ttgattgtct gaagaggggc cctttttaat tgaagttccc acttcctttt gaatttcctt
    14041 gaaggctgtt tggacttcat tgccaatcac cacttggtat tgtccaccgc tatccaccac
    14101 actaattaca ccaagtgttt tttctaaggc tttcgtatcg gctttccttt tatctttgag
    14161 ttcaaaacgc agtctggtgg cacaatgggt taagctgacc acattttctt ttcccccaac
    14221 ctgttgcaat acatttcttc ctacttctct gtaatccatt attctctctc cttaaagcag
    14281 taaaaaagac caagtcaaac cacgccccaa tcaacattga agtgttagtt tgtcttggtc
    14341 ttgcctgcat aatcagtaac atgccaataa cgttattttg ctgtaatcca ataatagcac
    14401 attatgatag cgcaatcaac agggaattta attttttatc ttttcgtttg accgtatagg
    14461 gtaatataac agttagatca catcaactag ggtatatctg cgtatactta ctgctaaaat
    14521 aagtatatct aatattaact ataccagtaa aaccattcct acataaccag cgggaaattc
    14581 ccaaaatcgt gaaagcatca aaaatgcata taacggatca cacaacttca acaattctgc
    14641 tcttgggaaa aattgatgaa tttggtgagt aaaggatgga ataaacagca ttccaacaat
    14701 ataggcaaca atagtgatac ttgttttttt ggtaaaaatc agtaagcaat agccaatttc
    14761 aatcattccg agatataaag gtatcgatag aatgatttgg gctagtattc ttaaaaatta
    14821 actagcaaat gtttaaactg atttatttct aatctacatg tagtaagtat ttcaattcca
    14881 ccaattatca ataaaaatac caaacatatc cataataatt ttttcttttt catttctttt
    14941 atattgttat aacagtgaat aacataaaaa ttcccgacaa tcattgtaat atttttttgt
    15001 cacctgtatt agtatttaat ttataggaaa ctataaaaac tccctagtga atttacacct
    15061 ttgggagttc ctgtttggac ggtatgcata atacatttaa atcaatttaa cattaacacc
    15121 tcagcatatg gtatctccac atatatacgg tctttctttg gatagtactc aatatttatg
    15181 ttgatagcac ttccattgtc taatatagct ttagcccggt atgtgttatc tccattttca
    15241 tgagtaatcg tcacatcatc acatgatcga tttaagttgt actgttcttg taaaatctgt
    15301 gttaccaatg gttttgatga cttctctaat ccagatgtac ctgtcatttt tgaaaaaata
    15361 atacctataa tagccaagac aacaatacct ataatgacaa acttcttgtt catatttact
    15421 ttattcaact ttttatctcc tatctccaaa ataatttgct cttatccctc ttatcagtac
    15481 attgacatcc ctaaaagtac accaaagatt gctccagcta cccctgctat catcaaaatc
    15541 gtacccattt tctcatcttt ttctcgatat aagtagccca taataacagc aacagcacca
    15601 aatacaacag gaataaatgc taacgatact accatagaaa tccaaccaat aatcaaatac
    15661 agcttccctg tctcttgtcc atgtacgatt tgttccttca tttcattaat tgtctgctca
    15721 gtacttttct ttactgtgtc tgttccggtt gtctcatctg tttcttgtag tgctccacaa
    15781 aactggcaat acttactttc atctgttatt tctttgccac attttctaca atacatgtct
    15841 tctcctccta aaatcattca attgcttatt agttaactgt ttactttatt aaatacatca
    15901 gaaaacagct cattcattgg tacacttaat atctcagaaa gcatcttcat ttgatagggt
    15961 ttaggaatcg ttctccctgt ttgccacgaa cttacacatt gctgtgtaac attcattttt
    16021 tttgctaact ccgtttgaga aagtcctttt tcttttctgt atcggctgag attacttact
    16081 tttttcatga ttctcccctc ctgttttatt atatacaaca atatgatgta tttcaactca
    16141 taaaatataa aaaacttcaa ataccattac aaatacaaca acttgttgta ctatactgag
    16201 atgggggtgt attaatgaaa cagaaacaat atgcaaaggt cattagagaa aagcgaaaag
    16261 ctctcgggtg gacacaaaaa gaattagctg aaaaaatctt ctctacacaa caggcagtag
    16321 caagatggga aaattctgta acagagccta acctcgatag cttaacagct ctttctagag
    16381 ccctaggaac ccctgtaagc cattttctag acaatgttgt cgtagattat gaggaagagt
    16441 ttttggctct ctatcgttct cttagcactg aagatgcagt tcgaacaatt gactatatga
    16501 agctattaaa aaggcaagaa aatgaacgca atcagctatt gaaagattga aaaataaata
    16561 acccaccgaa ctttaacggt gggtgtattg agatgaaata agattaagag ctatggataa
    16621 cctgtctagt ttaatacaat tgggtctttt ctcttcctta ctctccgtcc atcatctctt
    16681 gttacacttg taaattgata cagaggaact atcccagctc ctgataatat caattctttt
    16741 attgtttcat ctatccctgc ccctttcgct aaatatatta aaaaactact acttgctttc
    16801 acattgtata gtttcttaat atccttagaa gctcgttcaa gagtgaatcc ttgtttaaca
    16861 aagtagcctc tgttttttat taaagcattt ttcacgctgt tatccccaac attacgtagg
    16921 cgttcacaaa cagtgttaat aagttctttc tctgtcatta gatatgtccc ttgccacgat
    16981 aagccctgta aaacttcatg tgcttcatct aaaatcaatt gtttttcctt gctgagttct
    17041 gatcgggaat tttgaggaaa tactctttta gcctcttttt cgttaaaaca tatcttaacc
    17101 cattcataag aaaaatattg atatgtaaaa tgaatttttt ccagaagtgg aaggatatct
    17161 tcattcaatt tttgaatcac agaagttgca ttaaaaacgt ctaatcgata gacattgctt
    17221 ctcttatgat taaagtttcc taacgctttc tcttccttta acctatttag gtattcgagc
    17281 atcttcaaag gaacatcttc atcatctaat ttttttatca atcctataaa agtcataagt
    17341 gatagtaact tattacattt atctatgtca taagttttac catagtaaga actcattttt
    17401 ttagctaatt gttcccccga caaaatacaa gtcacacttt ccttactatc atcaaaaaaa
    17461 ttaacatcag aaagcaagac atcatagaca cgtcgcattt cctctagata attccttatt
    17521 gtcctgaaaa gtttgtcttt cattgattca agagtgtcaa aaagtacttt tgattcctct
    17581 ttcaattttc gaaaatgtgt aggatacaag tctaggttct ctaatagcca attaaatgtt
    17641 tctacccgac tgtctttctt taaaattagc atcacaactc caataaaatt ttcactgata
    17701 tcacaattac tggaatgaca ataaaaaatg gaatgcccag ttttactggt aaaaatacta
    17761 gcagagggat tatgatcgtt gtgaaacaga catcttaagt ttttacttga cttaagtaat
    17821 ttattcatat caatggttaa caatctttca taaatctcat taaaagacat gtcggaggaa
    17881 tcaaacaggc agtctttaaa ccactgtttc atttcttctt tgtcgtcatt ttttatcaac
    17941 ttaacaaaat cggtttcatt gactagttca tactctctcc ctgaatcact ttgacaattt
    18001 ttagaacatg tcatggtaaa atcaatcgga agctcagtaa tatctaacat gttgtcttca
    18061 ttaattatta tcactgcatc tgacttatat cctccaaaaa acattctatt cgaagcattt
    18121 acattgtcat cacacccggg gatgttcttt ttcaagtatt cgtaaacagc aaccatttta
    18181 ccatagtcag taattgcttc ttttaataga aagacaatct tgtatttttc tagattttca
    18241 gagtaccgaa tacttttttg tatcgcaaac gcagaattat gaactaaatt gatagataaa
    18301 accttttcta cgcttaagta tctactatca tctttactca aatctactac cttccccttc
    18361 tcatctttaa cagtgttatc gacatccaga ataattactc tggtttccac aaaactctcc
    18421 ttgtcattgc ctttattctt tgtcttgctt ggaataaatg attgtgatga atttagtatc
    18481 tctacaaact catctcttgt aacttctcta tagttatcta aacacctatc tcttacatca
    18541 gttttttctt tttttgtaac tggcttctct aataattttt cttgatctac ataaattgga
    18601 atattaatca ttgatgtttc catttgtgtt tcctccttat aaaattctgt taaagactaa
    18661 aacatacaga taataaaaac aaactcttta ttactatatg ttttagtctt atttgtttac
    18721 tcaaccttta taccgttcca tgaaactatc aatatcagat tttttaaatc taatgaccgt
    18781 atcaattttt ataacaggta acccgtattg agaaacatat tttctaatcg ttcctactga
    18841 tacacctaga tattcacttg cctgctgata gtccatatac tctagagtga ctccagaaat
    18901 aatgtcttct agcataggct ttagcactgt aattatctct ttcacttgtt gttcaacttg
    18961 tatagaaaca atgctatcaa tgatttgtag agacatattt ccccctcctt tcgtgattgc
    19021 ttgaacaaat tttctaagaa ttatcttcgt attttttgct caaaataaaa gtattttgtt
    19081 attaaccgat taatcaaaca aaaaatgatt accagttcat cgacatacac ataatacctc
    19141 gataaaaaag gggtgtcaac atctttgtaa aatttattta caacacccct tttttgaggt
    19201 atactaattt taggaggtgt ggtcaatatg ataaaacgtc caccaataaa ttatttagaa
    19261 cgaaaaaaga tactcggaac aaaaataaaa gctataagaa agagtaaaaa attaacacaa
    19321 ccagcatttg gtcttatgat taacaacggt caattaattg acaaaaaaac tatctacgaa
    19381 tgggagaagg gaacctattt accaatacca gagcgattat cccgaattgc tgatttggga
    19441 aatatgagta tagaggagtt agtttgtggc aatgtagaag aatatatttt gggaattatt
    19501 ctttatagag atagcattgt actagatggt ataacatttc cagataaaaa cctgttccag
    19561 catcttcgtc aacagttccc accagtacac tctaatttag atacatggct ggatagatat
    19621 tccaaattag aaccagagat gcaagaattt attgctaaca agacttgtaa taaagttaaa
    19681 aatgaaaaaa ttagtctttt caatatctta aaaatagaag aattattcat caatgctatt
    19741 gtagaaaaat ttgacaataa cattcttttc ctcactagca gtatagaaga actactagaa
    19801 agaatggtag atgaatggct acctattcaa ttgaaagaca tgtcttatcc cgaagaagct
    19861 gtgagagaaa ttactgataa tataaacaag ctagaacaaa cgatttcatc aattgggaaa
    19921 aaatacacta agaaaaaaat gaagggaggt gataccatct agtggtaagt actccttgta
    19981 aactaagagg agatgattta atggcaaaaa tatcaaagta caaaaagaaa aacggtcaag
    20041 tggcgtggat gtataaagga cacattgcca ccgatccacg aactggtgaa aaaataaata
    20101 ctacgagaag aggttttagt agcaaacaag aagctcaaaa agattatgac gagtacagac
    20161 atcaaatatt atacggtgtt aaaaagaaag cacctgatat gacatttgaa gacctgtata
    20221 atgaatggat aactcatcag cgtaccagtg ttaaagcttc aacaatcgca atctcagtaa
    20281 gatacgcaaa taatcaaata cttccagcat ttggtaagct taaactatcg aatatctctg
    20341 tcccatattg tcaaaaagtg gtagatgaat ggcacagtaa atatgaaagt tacgattata
    20401 tgagaaaaca gactgcacaa attttacgct acggggttgc aatgcaatat attgacaata
    20461 atcctatgga aaaaacactt cttccacgaa aaaaagagta tgagaaaaat cgtaaatttt
    20521 actcaaaaga ggagcttaat aatttactgg atgcttttaa agattttggt aacatgaaac
    20581 aatacgcctt cttcagatta ttggcataca caggtatgag aaagagtgaa gtactcgctt
    20641 tacagtggaa agacatagac acgtttaata aagaactaca tgtcaataaa actcttgctg
    20701 tagatgaatt tggtaaagtt ataattcaat ctccgaaaac aagagcttct agacgagtta
    20761 tctctttaga tactgagact ctttctatcc tcaacaactg gaaattacag caaaaagaag
    20821 agtatttaaa acttggatac aatactagct ctaaagagca acatgttttt acaacagtta
    20881 aaaacactct atacattcca aacactgtta atgattggtt aagatatatt ttgaaaaaat
    20941 ataacttgcc tcgtattaca cctcatgggt ttagacatac acatgctagt ttattattag
    21001 aagcaggaga atctgtcaag gtagttcaac aacgattagg gcatgaaaat agtaaagtga
    21061 cattagacat ctatgcacat attacaaata atgcacctaa gaaaacaggt caagactttg
    21121 ctgatatgat ggctcatcag taaaagagct ggtcaaaatc tggtcatttc tagtatacag
    21181 gcaaaacaaa aaagctagaa cccttatata tcaagggttc tagctcctat aacaggttta
    21241 cccaacactg ccttccatct cataactgat caatcgattg agttcgactg catattccat
    21301 tggaagttct ttggtgaatg gttcaacaaa gcccatgacg atcatttcag ttgcttcaga
    21361 ttcggtcagg cctcggctca tcagatagta gagttgttct tctgagattt ttgagacttt
    21421 ggcttcgtgt tctaaagaga cttggctgtt gtggatctca ttgaatggga tcgtatcgga
    21481 tttcgaccat tcgtccatga tgatcgtgtc acattcgata tgagagatcg aacccgcact
    21541 gtttttggca aaggttactt gtcctcgata gtttacttct ccgccgtctt ttgaaattga
    21601 tttagagacg atagagctag atgtatttgg tgcattgtgg atcatttttg cacccgtatc
    21661 ttggatttgg tttgctcctg caaaggcgat ggagagcatg gtgcctcgtg caccttttcc
    21721 atctaagtaa acacttgggt atttcatcgt tgtttttgca cctaggtttc cgtcgatcca
    21781 ttcaacggtt gcgccttcgt atgcttttgc tcgtttggtt actaagttgt acacattgtc
    21841 tgaccagttt tggatcgttg tgtaacggca atacgcatct tttcttgtaa agatttctac
    21901 gatggcggca tgcaggctgt tacttgaata agtaggtgcc gtacaacctt cgacatagtg
    21961 gatgcttgct ccttcgtcaa caatgatcag cgtacgttcg aattgccccg tgttttccgc
    22021 attgatccgg aagtacgttt gtaatggaac atcgactttg acggcttttg gcacgtaaat
    22081 aaaggtccca cctgaccata cggctgaatt cagcgctgct aatttgttgt cggttggcgg
    22141 tacaagtttt gaaaagtact ctttgaataa ttcagggtat tctttcaaag cagagtcagt
    22201 gtcagtaaag acgattccta acttttcgaa ttcatctttc atattatggt acacgacttc
    22261 tgattcatat tgtgcggaag caccggctag ataagctcgt tcagcttctg gtataccaat
    22321 cttttcaaat gtatctttga ttttttctgg tacgtcttcc cagtcacgag cgggtttgtc
    22381 acttggtttt tggtaatatt tgatggcatc gaaatcgatg tctgaaaggt cggggcccca
    22441 tgtttgcatt ggcattttgt taaatgtttc tagagatttc agacggaatt caagcatcca
    22501 ttctggttcg cctttgattc ttgacatctc acggatcact tcttctgtca agccttctcc
    22561 tgtactgaaa accggttcga catcatcgtg aaacccgaat ttatattctt ctaattctgg
    22621 tacgcccatg ttctcactcc tcttccttgt ggtaatgatg gaaagctgcg gtaccatcgt
    22681 tttccattgc ttttcctagt gctttccagg caagtgtcgc acatttgatc cgagcgggaa
    22741 atttagctac accaccaagc atagcagcat cgcctaattg gtcgggatct ttgacttctt
    22801 ttccttggac aagctgtaga aagtctacag ttaaatgttc tgcttcttct attgattttc
    22861 cgatgacggc gtctgtcatc atcgaggcac ttgccgtact gatggagcag ccactgccgt
    22921 caaaggcgat atttttgatg attccgtctt ttacatcgac ttgcaattcg atcacatctc
    22981 cacatgtggg gttgttcaat tcgatcttgc ttgtcgagtc agtcaagctt ccacgatgat
    23041 gcggatggga agaatgatcc aagatcactt gacggtataa attgtctaat ttagatagtc
    23101 ccatgttgga aaaactcctt tgttgccatg attgcttcaa ctaaacggtc ggcgtcttgc
    23161 gttgtgttgt agaaataaaa gctcgcgcga gcagtcgctg atacttcaag gtacttcaat
    23221 agcggttgcg cacaatgatg acctgctctg acggctaccc cttccatgtc taaagctgtc
    23281 gcgacatcat ggggatgtaa cccatccaaa ttgaatgcaa cgactcctgt ccgaaaattc
    23341 gggtcttgtg gaccataaac agtcaatcca tcaattgctt gtaattttgg caacacataa
    23401 gcggctagtt cttcttcata tcgatggata ttgtccatac cgagtttttg caaataatcg
    23461 attgcatggc ctaatgcgat agcgccggcg atatttggtg tccctgcttc gaatttccaa
    23521 ggtagttctt tccatgtact gtcgtataat tcgacaaaat cgatcatttc gccaccaaat
    23581 tcaacaggtt ccatttcttc taaccatttt cgtttaccat ataaaacacc aatacctgtt
    23641 ggtccgcaca ttttgtgtcc gctgaaagca aagaaatcac agtctagtgc ttggacatca
    23701 atggccatgt gcggggcaga ttgagcacca tctactacga tgaccccgcc gttttcatgg
    23761 acaagttcag ctaattcttg aacaggattg aagacaccta agacattgga tacatgagca
    23821 atggagacga ttttggtttt gtccgtaatc tttttcgctg catcctccat atccaggaag
    23881 ccttcttctg ttagttcgat atatttcaag acagcacctg ttcgttttgc caactgctgc
    23941 cacgggataa cattagaatg atgttccatg taagagagca ctatctcgtc tcctgctttg
    24001 atatagcggt cgccgaaggt tctggctacc caattcaagc ttgtcgtcgt accacgagta
    24061 aacagcactt ctgctgtttc ttttgcatgg atgaacgccc gtactttttc tcttgcttgt
    24121 tcataatcat gggtcgcgcg ttctgctaac gtatggacac cgcgatgaac attggcgtta
    24181 tcgtgttcgt aatagtacgc taatgcctgg agtacttgtt ttggcttttg ggtcgtcgct
    24241 gcattatcca gataaactaa aggttcatca ttgacgtctt gaaataagat aggaaaatca
    24301 ttgcgtagct ttttagcatc gatcatccat tcaacttccc ttcgattact tcgactaatt
    24361 ctttccgaac ttgttctaca gggattgctg ttaagacaga accgaggaat cctcgaatca
    24421 ctaagcgctc tgcttcttct ttatgcaatc ctctactcat cagatagtac atttcttctg
    24481 gatcaactcg tcctacactg gcagcatgtc cagcagttac ttcgttttca tcgatcaaaa
    24541 gaataggatt cgcatcacca cgtgctttat cagaaagcat caagacacga ctttcttgtt
    24601 gggcatctgc accttttgcc cctttcaaga tgtggccgat accattaaag gtcaatgttc
    24661 ctttttctcg gatcactccg tgttgcaaaa tatgcccgat cgtatgaggg gctttattgg
    24721 ttactcgtgt atcgattcct tggatttgtc tgcccgagct gattgccacg attttgactt
    24781 ctgcgtgtgc accttctcct gctaaatctg agtcaaagtc agcgatcaca tgaccgtcat
    24841 tcatgacacc aattgcccag tcgacagaag catctcgtaa aatgtgccca cggcgattca
    24901 tataagaagt aatattttct cctaattgat ctacggctga atatttgatt tttgaaccag
    24961 ctttagcgat gacttccacg atgatattac ctgatgattt tgctacttgt tctttggttg
    25021 tctggaaacg ttccagataa gaaaattcac tatgttcatc tgccacgatc aacacatgct
    25081 tgaagaagtg ctcatcggat gcgccatctt gaatgaataa ggactcgagt ggttcatcga
    25141 tcacgacatt tttaggcaca tacaggaaaa taccgctgtt cataaaagct acatggagtg
    25201 cagtcaattg gtcttcgttc atgtttactg cttttttcat ataatattct tggactagtt
    25261 ctggatattc gatcattgca gtgaacaagt cggtaaaaat gactcctttt tctgctaatt
    25321 ccacaggcag ttgttcaaaa atcgtccatg aaccttgttg gacaagcaca ggattgtctt
    25381 tcattgcatc aaatgccgga atcgtgcctg tttcactgat ggtttgtgtt tctttcacat
    25441 caaataacga ccagcgatgg aatttcaccc gatcgatatg cggcaatggc agttcatctg
    25501 ctttcgctag tgcgtcttga cggaaggttc tcatccaatc aggttcgcct ttacttaaag
    25561 aaaaatcatt taccgcgtca agataatcga gccagttttt ttctttcatt cttgctcccc
    25621 cttacgcttc ttcttcttta tagtcgattc ctaattcttt actgatacca gcgtagcctt
    25681 ctgcttccag acgtttagct aggtcagcat tccctgtcat gactactcgg ccttccatca
    25741 tgatgtgaac gacatcaggt gtgatatagt tcaataatcg ttgatagtgg gtgatgatca
    25801 atgcaccgaa attgtctccg cgcatttcat ttactccttt agcaacgact ttcaaagcat
    25861 cgatatccag acctgaatcg atttcgtcta aaattgcaaa tgtaggttct aacatcaaca
    25921 attgcaggat ctcattccgt ttcttttctc cgccagaaaa accttcgttc agataacgtt
    25981 cagccatttc ttctggcata tttagtaaag ccattttttc atctaacttt ttcaaaaatg
    26041 ccataacaga aattttgtcg ttttcatcac gtttcgcatt gatcgctgca cgcatgaatt
    26101 ccgcattcgt gatacctggt atctcacttg gatattgcat agctaaaaat aagccaagtc
    26161 gcgcacgttc atctacttcc aagtctaaaa catttttccc gtcaaacaaa atttcgcctt
    26221 ctgttacttc atagtttgga ttgcccatga tagcggcaga taaggtagat tttcctgtgc
    26281 cgttaggtcc catgatggca tggatttctc cggttttcat tgttaggttt acgcctttaa
    26341 ggatttcttt ttcctcgatc gacacatgta gattttttat ttctaagaca gacatgcatt
    26401 atacccccaa attctctttc gttctcactc attttagact aattgagaat gaagcgcaat
    26461 gaccttcctt actaaaatca aatatctttt atttattatt aaacaatttt gatttctaaa
    26521 ttagaatagg tataaaaaag atgagaaata agccattaca gacttatttc tcatcttttt
    26581 tgttccatac cttattttgc atcagccttt actggtttaa cagagccgcc ccatttgtct
    26641 gttatccatt cttggacttc tttgcggtga agcacttcaa tcagtttttt gattttgtca
    26701 ctgtcttcat cacctttacg agtcgcaata atattcacgt aaggagagtt gtccttttca
    26761 agcaatacgg catcttctaa tggattcaac cctgcgccgt aagcgaagtt tgcgttgatt
    26821 gcaactaggt caccttcatc attttggtac gtagaagcta aaagtgatgg gtcgatcgta
    26881 tggttgaact tcaagttctt agggttttct tcaatatcat cgaatgttgc tgtttccaga
    26941 tctactccat ctttgacttt gactaagcca gcatcttgta gaattgtgat gatgcgtccc
    27001 cagtctgatt cagaatttga agtaatgatt gttgcaccat cttttaattc ggaaacatct
    27061 ttgacttttt tagagtacaa gcccattggt tcgatgtgga cagcaccggc attgacaaag
    27121 tcatatcctt tttctttgat ttctttgttc aaataaggaa tatgctggaa gtaattggca
    27181 tcaatgtcgc cttcttccaa agattggttc ggtaatacat agtcatcgaa tttgacgatt
    27241 tcaagatcga ttccttcatc tttcaataat ggtttcacat gttccaaaat ctctgcgtgc
    27301 ggtgtcggtg aagcgccgac tttcaatgtc gtgtcgtctg ctttatttgc tgaatctttg
    27361 ctgtcgctgt tgttaccgca tgctgctaat cctacagtca gcaaaagcgc tgctgcaaat
    27421 ccaaaaattt tctttttcat atcctacatc cccctatatc ctattatctt ttgtctgttt
    27481 tcttagttaa gaaatcaccg attccttgaa cgataaatac gattagtaaa ataattaaag
    27541 tcgcaacgaa tgtcactgtt agattaccac gctggtagcc ttcctgccaa gcaagacctc
    27601 caagtccacc tgcgccgatc gcgccggcca tcgcagtaaa tccgatcatc gagatcgttg
    27661 taactgttaa tccagaaatc aatgcgggaa tactttcagg tatcaagacc ttccagatga
    27721 tttcccagta acttgctccc attgcatctg ctgcttccag tacaccaggg ctgacttcac
    27781 gaaaagcaat ctctactaga cgggcataaa atggtgctgc ggataaaaca agagctggaa
    27841 tggctgcttg cgcacctagc atagtgccta cgattgcttt agtaaatgga atgatcaaaa
    27901 ccatcaggat cataaatggc gttgaccgga aaatattact gatgatcgat acgattccat
    27961 aaatgattcg agcatacggt ttgtttttgc gtccaataga gtaaaggatc aatcccaaaa
    28021 ctaatccgat gatcgtcact aagaccattg agattaatgt catatatagt gtatcaagga
    28081 tagcctgatt catcgtttcc gggttgattt gtttaaaatc tagatatgtt tctgaaaagc
    28141 ttttatccac gatggatcac ctcaattcct actccttgtt ctttgatgaa cacttctgct
    28201 tgatctaatt ctttggtttc accagtcatc aagacagtca atgaaccaaa ggaaccttct
    28261 ttcacttgtt tgatctttcc atacacaacg ttgacatcga tgttatagcg tcgaatcgct
    28321 tgggaaatga ctggctcgtt ggcatttctt tcgctaaagg tcaaagttgc caaacggccg
    28381 cttggatttt ctttgatgag ttcagctaat agttctgtcg aatcagcttc tggttcgatg
    28441 tcttgttgta caaagcgttt ggttacttct tttttcggtt gtctgaagac agtcaatacg
    28501 tctccttctt ctacgacttt ccccaactcc atcacagcga ctttgttgca gattttgcgg
    28561 atcacattca tttcatgtgt gatcaagacg atggtcaaat tcaatttctt attgatcgct
    28621 aacaataagt ctaatacttc ttctgttgtt tgcgggtcca atgcgctagt agcctcatca
    28681 caaagcagga tctcaggatc atttgccaat gctcgtgcga taccgacgcg ttgtttctgt
    28741 ccgccggaaa gttgtgaagg atatgcttgt ccgcgtcctt ctaacccgac taaacgcaac
    28801 agttcttctg cccgttcttt acgtttgctc tttggtacgc cagctaattc cagcggcagc
    28861 tggatatttt caagtacagt tcttgaccat aacaggttga aatgctggaa gatcataccg
    28921 attttctttc ggaatgtacg taattctttg ttttttaatt ttgtaatatc ttgatcgttt
    28981 acgatcactt cgccgctcgt gggaagctca agtccattca ggagacggac taatgtactt
    29041 tttcctgcgc cagaatagcc gacgattcca taaatatccc ctttttcaac gtttagtgaa
    29101 acgtcattga cggcttggat gtttccgttt ttcccattga atgtcttttt gacattcgtt
    29161 agttggatta atgacatgcc attcacatct ttctcttatg atttttcaaa caaaaaagcc
    29221 ttcgccctct tgccttaagc aaaaggacga aagcttgaac ttccgtgtta ccaccttgat
    29281 ttaccgttac ttcgcaataa cagcctcttc cagtacttgg acttagcttc tttccgtata
    29341 ctgtcgcgct gtaacgggca ctcccgtagt aagtttgctt acgctcgctt actctgctct
    29401 aagaccatct tccatctcat tttcgttacc cattttcagc aaacagggct ctcttcaaac
    29461 gtccgtgaca tgtactcttc ttttcaaagc tttctcgttt catataggat tgcttatgat
    29521 tatagcaact ggaagaatca gtgtcaactt ttttcaagtg attttctgat tttataattc
    29581 gtcaaattct tttggatcaa catctttgaa acttaagatc cacgcattca tttcatctga
    29641 atcattcaag atattgatat cttcaccgat tttatcatta acagaagaaa ctgtacccgt
    29701 tagcgggctg gcaaattcat tgaccgcttt ttccgcttca acttcgatca gaggttcatc
    29761 tttttttagc gattgtcctg cttttggcag attggcaaac gtgatgtctc caagttcttc
    29821 ttgcgcttca tttgtcaaac caacacagta ttcttttcca ttaaataaga tccaaaggtt
    29881 gtcctttttc ttcaaatgct tgcctgccat tttatatcag ttctccttca taaatttttt
    29941 cattgaatcc aattgcaaca agctggtcct ctcgtaagat cagtggtcgc ttgatcagca
    30001 taccatctgt cgataagact tggctcgctt ttgaagccgt aaactcgcct acttgatctt
    30061 tcagtccaag ttcccgatat ttcatcccgc ttgtgttgaa caggcgacgg attggtactt
    30121 gactcgtttc tagccaagtc tcaatcgttg aggccttcgg tacttctttg atcatatcaa
    30181 cggtttgata actaacgcca tgctggtcta accacgcttt ggcttttttg catgttgaac
    30241 atttcgggta ccagtaaaag gtgtacaatt ttcttacctc cttgaagatc ttgcaggtgc
    30301 ttcattttgg tatctcatcg ataatatcaa cccgataccg atcatgttcc ctaaaatcga
    30361 ggatcctccc tgactaatga aaggcaatgg gatccctgtt aaaggaagta atccgatatt
    30421 tgctccaata ttctcaaaga catggaacag cagcatcatg atcaaaccgc ttgcgatata
    30481 ggcgtaaaat tcattattcg tatcgaaaca cacccgaatc atacgataga ttaaaataaa
    30541 atacaagaaa atgacgaatg caccaccgat aaagccgaag ttttcaccga taacggtaaa
    30601 aatcatatcg gactcacgaa caggcacata gatattgctt acgttgaatc ctttaccaaa
    30661 caagccaccg gtaccaattg ccaaaagtcc ttgggccggc tgataactca ttcctgacgt
    30721 atcatggaaa gggtccagcc atgaatcaat acgtgcaaac tgataagatt tgaatccaac
    30781 tttataaagc aagtctcttc cgccttcagt cgtaaccaag aagatcgttc ctgctccaac
    30841 gactactgcc aagattacta caggtgcgat gatgcgccaa gagattccag acatcaggaa
    30901 aatcccgcca aagatcgcaa gaaagacaag catcgttcca aagtcatctt gggccatgat
    30961 caatgctaaa accggtattg tcacgatcaa gagcttccca atcagccaaa agtccgattt
    31021 catcgtccgt tcttttactt gcgtattatg tttagttacg atcagtgcca tcatcaagat
    31081 gtacgcaatc ttcatcaact ctgctggctg gaaagtaaac gcaccgaatc gaaaccagtt
    31141 tttagaccct gttgaagcag ctaaattctg atcatagaat ttgagcaaga gtcccattac
    31201 cactaacccc aaaccataaa ggtaaggagt cagtttccag atccatttgg aattcaaatg
    31261 catgatgaca acgattgctg ccgctccaac taaataccag acaacttgca tccctacgcc
    31321 tttcaagact gctggattgt tcggatcatg gctaagtgct acatataatg agagcagacc
    31381 aatcaaacat aacagaaaga ctggtaaaat cacgccataa tcaatacgat tatcgttcga
    31441 agcttttaat tttttttcca tgtttcatcc cttttcttaa aaaccatact gctgattatt
    31501 atagcggtcc agttagataa tggaaagtct ttccatagac atttgggaaa aattaacttt
    31561 ccgtttgtgc agttgcttga gcaaatgcag tacaaaagcc tactgcttat ctttagtgta
    31621 tcatagaact ttttttgata catgcaatta tctaccagct gagattctcc tcgctgtgag
    31681 aagtttctgt gctttcattg tatcgaagga tctcttcggc aatctctagc agctgatcag
    31741 aaaccagatt ggttcgttgg atgaaataaa aatatcgatg gaaattcaac ggagtcattg
    31801 gcacattttc tggaacagag cgcttagaca aaatcgagcg accgattcct tccttcagca
    31861 acgcaacaat tacatcgtta cttttcacga tcatcttctt atcttggata ttcatctctt
    31921 caaaataacg ctgcgtgtaa tgaaaaacac cagagtttgc ttctcttaca agccacaatt
    31981 tgctttttgg gtccccagcg atgactagct ggtcttccat caaagagtat ctttgtacgc
    32041 cggaagtctc taatggcttt tcgataaaac caaaatcgga ttcatgtttc gctacttgtt
    32101 ctaatgattc atgagaattc gtgatttcga tctcaaaatg cactttagga aaccttttga
    32161 tcagatgttt catcaactga ggcaaaagat agacagcaaa ggtgtgggaa gcaacgatcc
    32221 gacatacttc ttcttcattt tgttcattga gcaatttttg ctgagtttct tcccattctt
    32281 ctaacaaaac cagtgtccgt tcatataata agtcggcttg cttagttgga agcatctctt
    32341 ttcttccgtt acgttgaaaa agatcgatat tcaattcccg ctccaactgt ttgatttgat
    32401 tcgagactgc tggttgagat aaaaacagta cttctgctgc tctggaaaaa tttcttgttt
    32461 catatactgc tcgaaaagtc gttaataact taaacatggc accacttcca taacttttta
    32521 tgataattac tataaaaact atttgattta aatatacaaa aaaccatcta taatagaaat
    32581 gtacaacaaa acagttgctg atccaactag taacttagat gaagacaatc agctgtctgc
    32641 ttgctcgtaa tcatacattc ctattcattt tacaatgtat tcgttcatct tggtactaaa
    32701 atctattaaa taaaaaggag aatattatat atgaagaact ttttgaaaat tattccgatc
    32761 ccgatctgcg ggttgatcct tgggttagct tcccttggaa atctgtttaa agactatcac
    32821 catgttgctt taggcaatct aactggcggt atctctatga ttcttatgat attcattttt
    32881 gttaaattgt ttatcttatt cgaacacacg aaacaaacgt tgcatgatcc aatcatcgcc
    32941 tccgtttcac caacttttac gatgtcactc atggttattt gtacttattt tgtttcatat
    33001 gaaagtattg caccaattgt caaattcatt tggctgtgcg ctgttatctt ccaagtgatc
    33061 cttgtctttt atttcaatta tcaccatgtt atcaaagctg atctttcaat tgaagcaatt
    33121 tatccaagct ggtttatcat ttacgttgga tttggggtca tcactgtaac tgccgggaac
    33181 ttcttcccac ttattggaaa aattttcttt tggatttcat tgatctgcta tgcgttctta
    33241 ttgccgatca tcatcaaacg tgtctttttc gtaagaaata tggctcatcc gacacgtccg
    33301 ctgattacga tcgttgcagc acctggttct ctttgcctaa caggttatct taaaaacttt
    33361 gctgaaccta atttttatct tgtcgtagca ttgttcgctt tatctcaagt attgtatttc
    33421 gttgtgctgt ctatgcttcc acgtttgttc aagcttcgtt tttatccaag ctatgcagcc
    33481 tttacattcc cgcttgttat ctctgcaaca gctatattta ctactgttca ttacttcaac
    33541 agtttaggta tctatagtag cgtattggat ttcttaaaag ttgcggaatg tctgtttgca
    33601 agtgtagttg tcttctacgt tcttgctcat tacgtacgtt tcttaattaa agaacatagc
    33661 aaacatggaa aatttgtttc taaaaaaatc gcttaataat cgattcaata ggttgtgaaa
    33721 aagctgttct gcatcaagta ataagaacgg ccaaacaaaa acagctgttc atgtttttgt
    33781 actggttggg cttattaccg cagatgcaag cttttgaaca ccgtttacca agaggtcgta
    33841 a
//
LOCUS       DACGMI010000033        33776 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.034, whole genome shotgun sequence.
ACCESSION   DACGMI010000033 DACGMI010000000
VERSION     DACGMI010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33776
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.034"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(51..386)
                     /locus_tag="IXT46_001661"
     CDS             complement(51..386)
                     /locus_tag="IXT46_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947577.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            complement(400..1434)
                     /locus_tag="IXT46_001662"
     CDS             complement(400..1434)
                     /locus_tag="IXT46_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAQ4947578.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            complement(1524..2204)
                     /locus_tag="IXT46_001663"
     CDS             complement(1524..2204)
                     /locus_tag="IXT46_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAQ4947579.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            complement(2488..3591)
                     /locus_tag="IXT46_001664"
     CDS             complement(2488..3591)
                     /locus_tag="IXT46_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAQ4947580.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(4220..4690)
                     /locus_tag="IXT46_001665"
     CDS             complement(4220..4690)
                     /locus_tag="IXT46_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAQ4947581.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGLFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            5020..6660
                     /locus_tag="IXT46_001666"
     CDS             5020..6660
                     /locus_tag="IXT46_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAQ4947582.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            6814..8136
                     /locus_tag="IXT46_001667"
     CDS             6814..8136
                     /locus_tag="IXT46_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAQ4947583.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(8204..8638)
                     /locus_tag="IXT46_001668"
     CDS             complement(8204..8638)
                     /locus_tag="IXT46_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4947584.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(8703..9539)
                     /locus_tag="IXT46_001669"
     CDS             complement(8703..9539)
                     /locus_tag="IXT46_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAQ4947585.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSIAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSGGAVVGGIAGNIVFEVFLRLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWIWYLICGGILGFLASFLGIGGGPI
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSGFMRFDLSMLFYIIPAAVI
                     GGLWGAKFSRILSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            complement(10113..10418)
                     /locus_tag="IXT46_001670"
     CDS             complement(10113..10418)
                     /locus_tag="IXT46_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAQ4947586.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(10443..10874)
                     /gene="ruvX"
                     /locus_tag="IXT46_001671"
     CDS             complement(10443..10874)
                     /gene="ruvX"
                     /locus_tag="IXT46_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAQ4947587.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(10871..11137)
                     /locus_tag="IXT46_001672"
     CDS             complement(10871..11137)
                     /locus_tag="IXT46_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAQ4947588.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(11392..12117)
                     /locus_tag="IXT46_001673"
     CDS             complement(11392..12117)
                     /locus_tag="IXT46_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAQ4947589.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(12478..12548)
                     /locus_tag="IXT46_001674"
     tRNA            complement(12478..12548)
                     /locus_tag="IXT46_001674"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12514..12516),aa:Gly,seq:ccc)
     gene            12665..13417
                     /locus_tag="IXT46_001675"
     CDS             12665..13417
                     /locus_tag="IXT46_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAQ4947590.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            13433..13912
                     /locus_tag="IXT46_001676"
     CDS             13433..13912
                     /locus_tag="IXT46_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAQ4947591.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(14163..15743)
                     /locus_tag="IXT46_001677"
     CDS             complement(14163..15743)
                     /locus_tag="IXT46_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAQ4947592.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(15736..16479)
                     /locus_tag="IXT46_001678"
     CDS             complement(15736..16479)
                     /locus_tag="IXT46_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947593.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(16655..17431)
                     /locus_tag="IXT46_001679"
     CDS             complement(16655..17431)
                     /locus_tag="IXT46_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4947594.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(17679..18515)
                     /locus_tag="IXT46_001680"
     CDS             complement(17679..18515)
                     /locus_tag="IXT46_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAQ4947595.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(18526..19455)
                     /locus_tag="IXT46_001681"
     CDS             complement(18526..19455)
                     /locus_tag="IXT46_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAQ4947596.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            19647..20000
                     /locus_tag="IXT46_001682"
     CDS             19647..20000
                     /locus_tag="IXT46_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAQ4947597.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(20074..20730)
                     /locus_tag="IXT46_001683"
     CDS             complement(20074..20730)
                     /locus_tag="IXT46_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAQ4947598.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            20956..22890
                     /locus_tag="IXT46_001684"
     CDS             20956..22890
                     /locus_tag="IXT46_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4947599.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(22976..24199)
                     /locus_tag="IXT46_001685"
     CDS             complement(22976..24199)
                     /locus_tag="IXT46_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAQ4947600.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGHSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(24193..26091)
                     /locus_tag="IXT46_001686"
     CDS             complement(24193..26091)
                     /locus_tag="IXT46_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAQ4947601.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(26085..27203)
                     /locus_tag="IXT46_001687"
     CDS             complement(26085..27203)
                     /locus_tag="IXT46_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAQ4947602.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(27286..28119)
                     /locus_tag="IXT46_001688"
     CDS             complement(27286..28119)
                     /locus_tag="IXT46_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4947603.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(28112..29029)
                     /locus_tag="IXT46_001689"
     CDS             complement(28112..29029)
                     /locus_tag="IXT46_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4947604.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(29256..30380)
                     /locus_tag="IXT46_001690"
     CDS             complement(29256..30380)
                     /locus_tag="IXT46_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4947605.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            30563..31471
                     /locus_tag="IXT46_001691"
     CDS             30563..31471
                     /locus_tag="IXT46_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4947606.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            31612..33225
                     /locus_tag="IXT46_001692"
     CDS             31612..33225
                     /locus_tag="IXT46_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAQ4947607.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT        10354 a         6680 c         5765 g        10977 t
ORIGIN      
        1 tacttaaaac aaaaagcgaa gtaaaaaaga aggagcgaaa aaatgaaaat ttattttgta
       61 gcaacatgtt catcctcctt ttcctttctt ctccataaca acaaccacgc aagaagccat
      121 aattctatac caatgatcaa ataaagaaaa cggatctttt cttcattcgt ctccgggaat
      181 acgccatgtt gattagattc tttataaatc ggtagctgtg tctgctgttt tgatgcgcca
      241 ttgactgaac cacttggatg cggaactgga cttagatcat aaaatgtaat cgtacctgaa
      301 cttttggtat ctgcttggac tggctcttgc cagctgaaga acagcaaact tgcaataatc
      361 cctcccaata agatcgatgt tttcaacgaa atcacctcat catgttgttt ctcctttttt
      421 ctttttcttg tggacccaca aaaacagcaa aatcaaccat aacactagaa ctgcagcaac
      481 caatcctgca taaagccatg ggaaagattg ttcttgtact gcaaaaacgg aattttcatt
      541 tactttttgt gctttttctt ttttgatcgt aaagttttgt gtaaatcgcc attcattact
      601 gtcgcctgat tttgctatga tttctgcgcg gtaatcgccg gcttttgctt tatcaccagc
      661 taaatcaaga ttcaagtgaa aattcgaatt tggtgcaact aaaaattcat tagacgtatt
      721 ttcaatataa agctgatttt cataaaagat cttgctcgta aatatcaaat tgctgataat
      781 cctaggctga ggattttgga aacgaagctg aacagttggc tttgcgttga cctcgtccaa
      841 atctcctgat aaaagtttca gatccggttc tatcgtctct tgactttctt gtaaaacgac
      901 tgcgagatta taagcaatac gatttttgat ttgtgctcct tctgtagcat tttctgtttc
      961 agcttcttct ttaggtgaaa catgaatacc cgctaataca cgtcccttaa agctttttgc
     1021 tgggattttc acttctatag gtatagttgt ttctgcatgt gctgatacat tgatttcctt
     1081 tttcgcaatg agcaaaacgt cacggacatc aaacggcaat gtctcatcta acgttgggtt
     1141 tttttgacta taatcgatcg ttccaccatc actcgttacc gccggattga cagagacctc
     1201 aaatgttcgt tcttcatctg aagaattgct gataattact tctagtgtct gattttgttc
     1261 cggtgccact aataaatcaa aataaccgat tgctttatct atttggttct ctggaaatac
     1321 cggtttgatt ccaaagtctc ctgctgaatc ctttgcttgg ctgattgacg gaaaaatgaa
     1381 aaatagactt aaaatagaaa aaaacgaaac aaacagtcgt ttactttgat tcattgtcca
     1441 ccacatcctt tcaacaacaa ctgcggtaaa aaatccttca cctatagtat tttcaccgca
     1501 gtttgttgaa tttatttcat actctatgct actgggccag ccacgaggtt ccaagtcaaa
     1561 tcagccgtga atgttccagc tgctgctttc ggcactttca gtgtgatatt tgctggatca
     1621 taaacagaaa gccatgttcc cagaccttga tcttttgctg ctgtaaatat tggtgtcgct
     1681 gcacttgctt tactcaaccc agttacagtt tgactagttg gtccagtgga ttcgttatct
     1741 gacgtacttt taacagtgga tgttccaaaa tctaattcag cgccttgcaa aacttgtgaa
     1801 ccgtttacaa aatctgaaac cgaaactgtc acgttccacc cttgtgcttg gccatctgca
     1861 cctacacctc gacgatctga tacttggaga taaggtgtat cgttttttga agcgtctact
     1921 tgatacgttt ttgttccgct ttcaatctcg tgtgtaccaa atggcaattc aggaactaca
     1981 tccaatgtta aagaacctgt ctggccagtt gctggatttt ccggatctgc tggctctact
     2041 ggttttgaag gatcagtagg gttaagaggc tcaacggtat ttgttggttc agtaaaggta
     2101 atatctcctt ttgaagtcgc ttgaccctca gcaaaagctg gtgttgccaa gccgcctaga
     2161 agaagtgttg aaagtaataa tgtcccaatc atgttctttt tcataataaa tcactccttt
     2221 ttcttagtga cctaagtata gtagagacag tatgcaaaaa atcctcatga attcatccgc
     2281 ttacttgaaa ttatgaccct ttttgtataa aagagaaaaa aacaataaaa tcgtttacat
     2341 gaatattctt ccttttttat taagtatgaa aaaatatttc aattttattt tttcgtttca
     2401 aattattcta ttagtgacat ccttgaacta taaaaatagg agtacggcat catctgccgc
     2461 actcctattt ttttcgtcat ttatttctta aataaaacga ttctcacgca attttatttt
     2521 tttgatatct tctactgttt gtgttccagc taattgcatg accatttcca attctgtttt
     2581 aaagaaatca aacacttgat ggactcctgt acttcctcct aaagacaatc cataaataac
     2641 gggtctgcca atagcaacaa gatcggcacc tgatgcgatt gctttgaaaa catgttgtcc
     2701 acgtcgtaca ccgctgtcaa acacgattgg tacacgttta tctactgctt ctgccacata
     2761 ttgcaacgaa tcaaacgcag caggcccccc atctaattga cggccaccat ggttagatac
     2821 ccaaattcca ccagcaccag attctaatga tcgatagaca tcttcttctg attgaacacc
     2881 tttcacgtag actggcaaat cagaatgagc agcgataaat tctacatctt ttggactaag
     2941 tttttgtttg gaagatttat atacagcatc catcgtttgg cctactcctg attgataagc
     3001 ctgaacgatc ggcattggca gcgggaaggt aaacccgttt ctgcggtctg tttcacggtt
     3061 tccgccaact gttgcatccg ctgtcaatac gattgctttt gctccattac gcttggccac
     3121 ttcaagaata tccaaattga ttccattatc tttgctcata taaaattgaa accattgcgg
     3181 tgctttctcc ccgcctgctt ctcttatctc ttctaaagta caagaagcgt aagaacttgc
     3241 tgtatagatc gtcccaaaat ctgctacacc ttttgcagaa gctttctccg ccttcacatg
     3301 agctaatcca tgagcagcaa ctggtgccat gatgattggt gcagtcagca tttcttcgtc
     3361 aaaatgtgta gttgtatcgg gtaattctac atctcttaat acatgaggaa taatcaaacg
     3421 atgattgaat gcccgttcat tttcttgata agtaaataag tcgccagcac cactgctgat
     3481 gtaaccataa ccaccagctg gaatcacttg tgaagccgcg atttctaaat cttccatatt
     3541 gataaaatct actattcctt catttgtacc tgcttgatat gttttttcca tctcaatgcc
     3601 ttctctctat aaaatttgaa tgatgaacaa tatgatagcg tttacacttt ttatattact
     3661 cttcgacatt gatacaggca aataatctgt ttacatttca gccattccag atgtcactac
     3721 tctggaagaa atgattgtaa taaaaataga taaaaaaccg atgggacttt gacaaaagta
     3781 gtgtcaaagt cccttttttt gaataaacgg tgttcaaaag ccattttctc ggtattaagt
     3841 caaatttatg caaaaatgtg gaaagccatt ttcacaaaat ttttcttact actcgaaact
     3901 aagcgacttt ttcacaacct ctcgataaaa cggtgttcaa tcagctgacc ctcggtatta
     3961 gctcaaaaaa tggcaaaata tgaggaacta ttttgccatt tgtctctcta atactcaggt
     4021 cagaacgttg acttcacagt ctcttcctta aacggtgttc aaaaacttgc atctgcggta
     4081 ataagcccaa ccaaacgaaa aataggagga gctatttttg tttggctgtt cttattactt
     4141 gatgcagggc aggtttttca cgacctctga ttcacggtgt ttctttttca tcaacatttt
     4201 tacgaaatac tgtggaagac tattgaaata agtgtggatt gtttctttgt gtttcaatcg
     4261 tttcttgcca ttcttcattt aattttggat taccgttttc ttccttgaac tcataaggtc
     4321 ctaattcaaa aagcccagac agtatttgat tcacgatttc atatagttca gtgtgatcag
     4381 acacatgatt cttgaagatc atctcattat caccacgttt gaacctcaca ttcgggctct
     4441 catgatgaac ctctatgcat ttttctcctt tttttaactg acggacttct gaaaacatct
     4501 cataaatatc ttctccagta aaaccttcag caagcgccag actgtccaca agaccgccta
     4561 ctgtcagttc agagattatt gcttgattgg aatctaattt taatgtatag cttgtcgctt
     4621 ctactacgcc acatgcattg caaccgcctt ctgatagttc gctttttcta atcaattgaa
     4681 cttctttcat tttctcttcc tcctcttaat tttctactta tgtattttta tcacctgaca
     4741 taggtgactc ctatcaacgc tatcatgtgc ttttttcctc agaaatccta tttatccatt
     4801 ccatctatcc cttattcttc tacttttctt tctctagcat ataagagata cgcatagtat
     4861 tcaagcaagg attgtcgata taaaaagaac aaatactgct attttgattt cttttggcta
     4921 tattacatat aaataaaatt tatcatacct gctctttttg actatatcat catctgactt
     4981 ctatacttcg tttgtattaa aacttaggag gaatcattca tgcttacagg gttaaactta
     5041 ttaaataatc cttttctaaa taaaggaaca gcttttacaa aagaagaacg ggcaaaatat
     5101 ggaatcactg gtatgcttcc aagtactgtc caaacactgg aacaacaatc tgttcaagct
     5161 tatggtcaat acttaagcaa acaaacagat ttggaaaaac gtatcttctt aatgaatcta
     5221 ttcaatacga atcggacatt gttttataaa ttgatgggcg aacatttagt tgaattcatg
     5281 cctgtcgttt atgatcctgt cgttgcggat tcaatcgaac aatacaacga aattttcttg
     5341 aaaccgcaag atgctgcatt tctttcaatc gacgaaccag aaaacatcaa agcaagtttg
     5401 aagaacgcgg cagatggacg agacattcgt ttgattgttg tgactgatgc agaaggaatc
     5461 ttaggtatgg gcgactgggg tgtgaacggt gttgacatcg ctatcggcaa attgatggtc
     5521 tatactgctg ctgctggtat taatccagca caagttttgc ctgtatcgat cgacgctggt
     5581 actaataatg aagaattatt gaataatccc ttatacttag gcaatcgtca tgctcgtgta
     5641 gaaggcgaaa cttactatga attcatcgat caattcgttc aatcagctac cgaattattc
     5701 ccagaattgt tattgcattg ggaagatttt ggacgaggaa atgctgcagc gatcttagaa
     5761 aaatacgaag atcaaatcac tactttcaac gacgatatcc aaggtacagg aattgttgtc
     5821 ctagcaggtg tattaggcgg attgaatata tccggtgaac aattgaaaga tcaaataatt
     5881 ttgacatttg gtgctggtac tgctggtgtg ggtatcgcaa acatcctttt agatgagatg
     5941 atccgtcaag gtgtacctga agaagaagca cgccaacatt tctatcaagt agataaacaa
     6001 ggtttattgt ttgaagatac agaaggattg actcctggtc aaatcccatt cgctcgcaaa
     6061 cgctcagatt tcactaatgc tgatgaattg acaaacttag aagcagttgt aaaagcgatc
     6121 catccgacaa tcatgattgg tacttctacc caacctggag cattcactga agaaatcgtg
     6181 aaagaaatgg ctgctcatac accacgtccg atcatcatgc ctttgtctaa tccaacaaaa
     6241 ttggcagaag caaaagcaaa agatttaata gaatggacgg acggaaaagc attagttgga
     6301 acaggtatcc ctgctgctga tgttgaatat aatggtgtaa cttaccaaat cggtcaagca
     6361 aataatgctt tgatgtaccc aggtttagga cttggtttga ttgcttcaac agctacacga
     6421 gtaaatgctg aaatcatttc tcaagctagt cgagcattag gcggaatcgt tgatgtaaca
     6481 aaaccaggag cagctatctt gcctccagta gcaaaaatca ctgaattttc tcaaacgatt
     6541 gctgaaactg tcgcaaaatc agttgtcgca caaaacttga atcgtgaaga aatcacggat
     6601 atcaaagaag cagttgaatc tgctaaatgg gttcctgaat ataaatcttt agaagattaa
     6661 gatcgttata gtaaaagaac atacagaaac tttgtatgac gtctaaaaag aaaaaagcga
     6721 ctgcggcaaa acagcggcca gccaactcct gctcttttgt cgcttttctt tggctttttt
     6781 catatgatac agaataagaa aggatctgta aaaatggcac aaaaaacaac aactgcaact
     6841 gcagttgagg aaaagaaaaa agaaggtttt tggtccacaa aaatcaccgg cgtaagtttg
     6901 ccactttatt tgatcatggt ccttgtcctg atcattgcaa tggctttagg gaaattaccg
     6961 acgaatatga ttggaccaat cgcagttttg gttattttcg gtaatttatt tcattttatc
     7021 gggacaaaaa tccctatcgt caaaagttat ttgggtggtg gttccgtttt tgcgatcttc
     7081 gcttctgctg cgattgctac atttgggatc ttacctgaat atgtagtgaa atccacagaa
     7141 aactttgtca gcaatatggg ctttttggac ttttatattg ctgccttgat tactggtagc
     7201 atccttggta tgaaccgtaa tctattgatg aaagcttctg ttcgttttat tcccgttgca
     7261 cttatttcaa tggtcgtctc cttttttgcc gtaggactcg tgggcatgct tatcggaaat
     7321 ggttttgcaa attccgtttt atacatctca ttacctgcga tggctggtgg tgttggagcc
     7381 ggagccgttc ctttatcaac gatttatgca aatgttttag gtacggatgc ttcttctatc
     7441 atttcccgcc tgattcctgc tacagcaatg acaaatgtct tagctatcat cggtgcagca
     7501 ttagttgctc gtgctggaca atcaatgcca aaattcaacg gcaatggtaa attaatggaa
     7561 aaaggcgatc ttggcgatgg aaaacctcga actgtgaaac cttccattcc acagttaggt
     7621 gttggtttga tggtatcatt gactttcttc atcttaggac aaattggtaa ctattttgtt
     7681 cctaaagtcc atgcatacgc atttatgatt attatcgttg tcatctgtaa aatcgccaac
     7741 ctattaccag agtattatga agatgcagct atcatgttca ataacttgat tgtcaaaaac
     7801 ttgacagcag ctgttcttgc cggtatcggt attgcgttgc tgaatctgaa tgtattagct
     7861 tctgctttga catggcaatt tgttgtctta tgtctgacaa gtgttatcgc gatttcagtt
     7921 gtttcaggat ttgtcggtcg tttgtttggt ttatatccaa ttgaatcaac tattactgct
     7981 ggcttatgca acaactcgat gggcggaaca ggaaatgtag ccgtcttatc tgcagctaat
     8041 cggatggaac ttattgcttt tgctcaaatg ggcaatcgac ttggtggtgc catcgttttg
     8101 atcatctctg gtttcttgat gcaattactt tcttagtcaa aaaaacaaaa atacctgatc
     8161 atcaagtatc ggcttggtga tcgggtattt ttttgataaa gatttacagg attttcaaaa
     8221 atcttttttg cattttatcg gaatgataac cgatgtgttc ataaaattgg tgtgcttcta
     8281 ctctgtattc tgcagaatta agccttattg tcgttattcc tcgttttttc gcttcttctt
     8341 ctacgccagt catcaaagcc tttccgatgc ctcttttttc agcatattta gacacagcaa
     8401 gtgccataat attgaacatt ggatcgctaa aaatcgattc ataggactcc gcttgtacat
     8461 agccagctgc ttttttagaa gtaggatctt cataaaccaa gaaaaaattt ttctctggct
     8521 ccttcagcag tttcttcatt tgtctcaccg taacggttaa tggtatatca taccctaatt
     8581 gatccgcatt gatttcacgt agtgcttctg catcttctaa acgcatttcc cgtaacatcc
     8641 aaatcaccag ccaatttctg attttttaaa atgaattttt ttatcatagt atactctttt
     8701 tttcatttag aacaatatgt ttcagtgatt ttgacttgcg ttagtctaga ttctcctaat
     8761 gtttgtaaga tgacaaaggc attgtaacaa ttgaccaaaa gaaccacgag gacaattact
     8821 tgaaaaataa aggtcacttt ttttggagac aaaatcctgc taaattttgc tccccacaaa
     8881 cctccaataa cagcagcggg gataatataa aacaacatag ataaatcaaa gcgcataaag
     8941 ccacttgtta aagcaatcgt tactaattta gccagttgag aaaagaaaat cgtagataga
     9001 gaatacagcg ttgcttcttt tattggcaag gcaaacatca gcatcagtaa tgaaacattg
     9061 atgggtccac caccgatacc caaaaagcta gctaaaaagc ccaagatccc cccacatata
     9121 agataccaaa tccatgacgt tagatgaaat tttggctgat gatgcttggt gtagaagaac
     9181 gcaaaaacca aggtcaatac cgtcaagaaa atttggatca gctgcacatg cttttcattt
     9241 tcaaacaacc gtaaaaaaac ttcgaataca atgttaccgg ctattcctcc aactacagct
     9301 ccaccagata cccaaccgac aatctgccaa ttcagcgatt tcccacttga tacttgtcgc
     9361 actgtcgaaa caatagacat cgtgaatact gcaaccgttg agtaaaaaga aatacctgca
     9421 atagaatggg caccgataag atcaagaatc ggtttgatca acacgcctcc gcccatgccg
     9481 gaaatagcgc caactgtatt tgccagaacg atcaccacaa aataaatcag accaatcata
     9541 tcatcttgta tatcctttct cttatttata tcttttagcg atttttactc tttgcttata
     9601 ttatacagta aaagaaacaa acgaggcttc gaaagctttt ctacttttta aggaaatgta
     9661 gtactaaacg aaaagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa
     9721 acaaaaatag ctcctcataa ttttcgtttg gttgaactta ttaccgcaga tgcaagcttt
     9781 tgaacaccgt ttaagaaaga ggtcgtgagc ctgccgttca gctccgagtc acaaggaaca
     9841 atttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg aggagttggc
     9901 aggagaacac cgtttaagga agagactgtg aagtcaacgt tttgacctga ttattagaga
     9961 aacaaatggc aaaatagttc ttcatatttc gccgtttttc gagcgaatgc cgaggggcag
    10021 ctgattgaac atcgtttatt tggaaaaagg gattgtgaca agacgtttgt cacaatccct
    10081 ttttttatat cttattaatt cattcttttg ttctattctt cttcttccgc catgaatgta
    10141 ttgaatactt cttcaatcat gtcccattct gcgtctgttt cgatttgttc taactcgcct
    10201 tctgttccat cttcgttttc gatgtatgca taagcttgta attctacatc ttcatcttct
    10261 gaaacaccag caggatataa aagaacatag ttacgtccaa attcttcttg tccgtcaact
    10321 gttagtagga tttcatataa tgtttcattt ccttggtcat ccaccaatgt gatgtgttcg
    10381 tgtccttcat ggtcgtggga atggttatgt tctgtcataa gattacctct tttcttttat
    10441 tattaaaata attgcttacc tgagccgtct aaataatttt gtaagatcat cacagctgct
    10501 aatttatcga tgactttttt tcgtttggct cttgaagtat ttgcctgctc tactagcata
    10561 cgttctgcct gaacagtggt taatcgttca tcttgataat caactggcaa ggagaatagt
    10621 tctttgatct tttctccgta tgacatggaa gcttctgccc ttggtccgat ggaattgttc
    10681 atatttttag gtaatccaac tacaaaccgg tctacttcat attgtgctac taattccttc
    10741 aaccgatcaa agccaaactc ttcttctgct tcattgatcc gaatgatctc tactccttga
    10801 gctgtccagc caaaggggtc actgatagca acacctactg tcttagaacc gacatccaag
    10861 cccattactc tcataaattc actccatgat ttgagaggta gtccttgaca attacttcca
    10921 tgatctcatc gcgttcgtga cggcgaatca aatttcgagc atcacgataa cgaggaatgt
    10981 aggccgggtc tccagaaagc aagtagccga caatctgatt gattggattg tagccttttt
    11041 cttccaaagc ccgataaaca atcgctaatg tttcgctcac ttcttttttg cgactatcgt
    11101 caaaaccaaa acgtacggtt tcatctgtaa aacccatgat tctacacctc tttcccgcaa
    11161 ggtaattcca gcttaccttc tacaacctta ttttactcga agaaagggaa aactacaaac
    11221 aaatattcca aacttccgaa taaattaaga aacactattt gtatgttttt ttcctttttt
    11281 ctgtagcttt atcaaaagta ctcttttcat aaagtatacg ctatatttct ttgaatgtat
    11341 gtttttacac aattttttca taatattcat aaaaaattcg aatagctgct actaattttt
    11401 tgtttttgtt gcttgtcctg tctcataatt gatcgtgtag ccatcttgaa cattgtagat
    11461 aaagacattg aattcaattt ttttgtcttc aatgctttct gcttccaatt gcactcccct
    11521 ggctaccagt tcattcccct caaaatgagg agtgacacgg tagcgtacat gatgatttgt
    11581 ttctttgata tatgccgcaa tatcattttc gtgagcaagc atgtatggag cattcaacga
    11641 acgtgtccct gtcatcaagt ttttaatgtt gttattttga ccagtcagct ggaaaccaat
    11701 taaatggctg cgattatata accattgccc gtcacttaat ttcttttgtt tccaacctgt
    11761 cgggtcaata tacaaaggct ctctcttttc agtagggaac aaatcttttc caagcatagc
    11821 attggcttgt cctactctgt tcaatttatc aatatttgaa tagctttccc atgttccttt
    11881 ggaaaggcta agatcctctt ttgtaaattc cggctgattc ccattgattt ctatttcttg
    11941 atgttttcca tcatattctg gcacatccgc tacttgagaa gcttgtggtg tggaatcaaa
    12001 aatagttgta atctgctgaa agatatctga atctttttgt gtggtggaaa caccgaatgc
    12061 ccctgcaatc acagcagcga cgatccccac gatcgccttg gttgtttttt tgctcatttc
    12121 tttactcctt tactaacagc tccctaaatc ttaacatatg ttcccctata aataaatact
    12181 agaaagaaat agaaacagca aaaaataaaa cctgttttaa gatggcttaa aaatacaaaa
    12241 aagagacgga ttcctcgtct ctaatcagtc accactctat ctgtaaggta tttattatta
    12301 ttcaaaaatt ttcttcatac tcaagacaat acactgattt cacaaccgct tggtaaacgg
    12361 tgcgcaaaag cttgcatctg cggtaataag tccatccaag ttaaaaacat aagaagttgt
    12421 ttttgcttgg ctgttcttat tacttgttgc agagcagctt tttcacaacc tattttaagc
    12481 gggtgacggg aatcgaaccc gcgacatcag cttgggaagc tgggatttta ccactaaact
    12541 acacccgcaa tacaaaaaca gtatacgcct cttttattcc ttcctcaagt ttttttattc
    12601 tttacgcttc tggtatgttt tgtagtaaaa taaaactaat caatcaatta ttggagaaga
    12661 tgctatgacg ggaaaagaat tagatctgtt gctggacact tgtttactcg ctgggaaaat
    12721 catgatggaa agcaatgcgg agatgtatcg ggtagaagat acgatgagtc gaattgcttt
    12781 agcttctgga aatttccgtt tggtcagcta tgtcactcaa accggtctct ttattggtct
    12841 tgatcgtacc tcgaccatcc gaatggaaca aattaccaac cgttcgatta atttagaaaa
    12901 agtagtaaaa gtaaatgatc tttcacgtaa atatgttgct tcagagctaa cattagaaga
    12961 actttactgc gaactgcaag caatcgaccg agaccgttct ttctttcctg tctggttgca
    13021 aatcgttagc gcggcagtga tcagtggaac aattatggtg ttatttggcg gaaagatgac
    13081 cgatttacct gtgactttag tcattggagg attgggatac gcagcttatc tatatagttt
    13141 gaaatttttt agaatcaaat ttttatcgga atttttatct tctttattga ttggcatagc
    13201 cgctatctac agcgtacgtt ttggcttagg aagcaatcag gatctaatca ttatcggatg
    13261 tgtgatgcct ttagttcctg gagttcaaat tacgaacgct atccgtgatt tgctagctgg
    13321 acattatgtc tcaggagttt ctcgcggaac agaagcgatg atgactgcta cgatgatcgg
    13381 ttttgcgatt gcttttattt tccagctttt ttattaggaa aggaacacaa gtatggggac
    13441 gatatttatt cagttttctt ttagtttttt agcgactgcg gcatttgccg ttattacaaa
    13501 tgtacctagg cgttcattga tttgttgtgg tctttctggt gcttttggct ggatgatcta
    13561 ctggatctgt gttcaaatag gcggatctgc tgcttttggt tcattgcttg gttctttagg
    13621 agtagcattc atcagcgatc ttttctctaa acgtttgaaa atgcccgtaa cgattttcaa
    13681 tattcccggg atggttcctc tagtccctgg tggtttagct tatcaagcgg ttcgaaatct
    13741 cgttactgaa tcctatcgag aagcggctca ttatgcggtc caagcaatta tgattgctgg
    13801 agcaatcgct ttaggtcttg tattatcaga agtctttaac cataacatcc gtaatttcaa
    13861 agtaaagcgt gacgcaatca tgatgaaacg aaaaaaacgg ctttttaaat aaacgaagtg
    13921 taacaaagaa aaggttgtga aagagacgtt cagccttgag cgatgacaaa atatctcaca
    13981 aacattgcga caagtaaccg caggagcaat aagaagtaat tatgagtatt aaaaaaagtt
    14041 ttgtaaaaat agcttctcac atttttacat aaaattgact taatactgag aaactgactt
    14101 ttgaacaccc tctatctgta aaaaaggggc tgcgacatga tttttgtcac ggcccctctt
    14161 ctttattcaa attttttcca aaacgttcgt tgataataaa cgatccatag agcggaaagt
    14221 attagaacta aaccgatcac aggaatattc actaaccaaa atggataaaa caaagccaac
    14281 attccgtata agacgataag aataatactg atgatcaatg aacccatcat agttgcgact
    14341 aaacccaaac ttcctgaacc tctgttaaat aattggttaa tattggtcca gttcagcagc
    14401 agcaaccgat aatctctagc gaaataacgt agtgacaata agtagcagcc gaataaagaa
    14461 ccaaatagca agctagggat aaaaaacaaa ggcagctgaa aagacagtcc gcttaataat
    14521 gcgatcccac cagttaaaaa actctgcaat atccatccga atctgaactt ttcttttaaa
    14581 tattggttca tagagattgg caaagaacgg ataaacagaa aattttcttg atccaaagaa
    14641 ataagattgc tgataaaaga agtctgatta actgttaaga aagccaatgc gatccctacc
    14701 aggaaaacaa caccgattaa cttattatct aaatcagtta attttatttc gcctcctagg
    14761 gcaaaagcaa gaataaaaat gattggagtt aacaaggaag aagaaagaac ttgcataatc
    14821 aaattaggtt cttttactaa ttgagcattg taactaaata aaagctgatg cacattttgg
    14881 ttctttttat gggttctttt tattttgaac tcactgtttg aatcagtcag ttgctctgta
    14941 agctttggta ctatcagctg ttttacagca aggaaaaatc ccagagccgt gatagctagt
    15001 attccccaac ccaataaacc ttgttgagaa agtggctgac tggcagcatc atagaatggc
    15061 aataatatcg aaatcggatg ccgatctgtt aactcatttt caatagtccc cgtttgatga
    15121 ttcatccaca tgattccagc aaatgcgatc agcatcgagc tgccaagcaa gatactagaa
    15181 actgtttttc tatgtttttt aaacactgct gttcgagcca aaccaaaaac aatcaaacta
    15241 gccagacaaa aaagaataat caaaaataga gaaaacaaaa ggattgagat aatgatagta
    15301 agcaaaatcc ctagatcagc tcgccatccg gttaaaataa acatgactag aagcggaaaa
    15361 acaaaaggaa tgatggtcaa agcaactacc aaaatctttg ctgaaaaaac ctgttcttgt
    15421 ccaaaaggca gaggcaaaaa tacttgcagg tcatttcctt caaaaaagat attataaatg
    15481 actgatatac tttgagttaa acctaacata ccaaaaagtg ccacgtaata agtaaagaaa
    15541 cctggcaatt taacaaagtt catagcaaac atagcaaatc cgtaaatcag taaaaaaatc
    15601 agccctgaaa aaagattttg agacaaaaga tagatagtta atcgctttcc cttttttcct
    15661 ttctctcttg ctttattcgt gagctgtgga ttaacatata aaagattaac tcgaattaat
    15721 tctaataatt gtcgcttata catacggtcc atctcctgtc gcttgccttc cagccatttt
    15781 caaataaatc ttttctagcg tttcatcagg tgagccattc aataattcac taactgcccc
    15841 ctgataaatc aattcacctt tcttcaaaat agccagttta tcgcataact gttgtgcggt
    15901 atccaataca tgtgtagaaa aaatgactgt ttttcctttt gcggcatgag ccttcatcat
    15961 ttctttcaaa tcaaatgctg cttgaggatc aagtccttgc aaaggttcat ccaataccca
    16021 aatatctgga tctggcagca acgtgccgat caaaatcgtt ttttgacgca ttccatgtga
    16081 aaaacttgcg attgtttcat tttgatgact atacatatca aaaagcgctg tcaattctgc
    16141 taaacgcttt tctttttttt gtgtgtctaa ttcataggca gctgaaatca agtcccaata
    16201 ttctccagcc gtcaattgta aaaaaatatc tggggaatca ggcacataac cgattttttg
    16261 tttgatactc aatcgatttt ccgtcaattt cattccatct actaaaatcg ttcccgatga
    16321 tggttcaata atactaacta aacttttaat cgtagttgat tttccggcac cattatgtcc
    16381 taaaaatcca aaaatttccc cttgtcttat cgagagagac aagtctttta atgcttgttt
    16441 tttcccgtaa cttttactta cattgatgaa ttcaatcatt tctgtactcc ttttgtttgt
    16501 tattactttt tattgtaccc ttcgttattg gtggagtaaa tgtcaaaaag agtgcataac
    16561 aaaaaaggat agaaacgact aggctgctac ttgggttgtt ctcttctaca ggaaaacact
    16621 cttctaacag gtaagatatg agtctttgtt ttctttaaaa tgattcattt tctatctttt
    16681 cttgcataaa attctttagt ttatcaatac ttctctttcc catctctagt tgttctccat
    16741 ttgcaaatgt tactatttcg tttactctgc taatagatgt aatgttttca gtattaatga
    16801 tataagcttt taaatcttta cataaatact catattcgag tgatttttta tattttttaa
    16861 ttgtgccgtt tacgagaatc tcttcatctt tcaatactag gcctatttta tttttataac
    16921 ctggcatgct cattagataa aggatttcat cgtaatggat atagtgatcg ctattaccat
    16981 aacggacagt tgtccacctt tttttcgtag catgttgaac aggatagttt tctttttctt
    17041 tcaataagta actttggatg ctttttttat ttttttcata agtgaattct tttatcaaat
    17101 aaccactagg cgtaatcttt cgattaataa cagttattgc tttattcgga tgagacgtta
    17161 gataaacaat tttacacttt tcattctttt ctctaagcat ttcgcctagt tcgataccgc
    17221 tataataggc gttcaaatcg atgtctagga aaaaaatatc tgaggaatag atttcattat
    17281 ttttaatgaa ttcaacaaat tgtataacgt tcaatccctg aacgatctca aatttccaag
    17341 gacttaataa aattctggat tcttccaaaa tttctactag cattttttca aaaaccaaac
    17401 tatcatccaa aataaatata cgcgttacca taaaaagtac ctccactcga tattttacta
    17461 tcaaaatcat ttcatacaac ttttcaacat acatgttagg aataaattgt aattctcttc
    17521 acaatctttt ccaacacctt tgaaaccgat atcaaatact ttcaggatgc tgcttctaaa
    17581 ataaatatca aacaaatgaa tacatcatgc aaaaaaagcc agacaaccga cgtccttgcg
    17641 tgtcagctgt ctgagctatg tttatttatt ttgttctttt aaaaagaacg atacacatac
    17701 tgatttttcg gagcagagac tttctcagcg tttgtaacaa ctacagatgg gatttcacgc
    17761 ttgaatggtt gataatagtc tgattggatg gttccttcta ttttatacca ttcatcattt
    17821 ttaaccgtta ctccttccgg catatgcgtc aacaaaccaa agactcctga atctgccaca
    17881 caatggataa tgccgaatcg gaacaagaag atatctgtat tgctatcgtt cggtgtttgg
    17941 taaacaaatc cttcatagct gatttttttg ccaatgaatt cgctagggta attataaatt
    18001 agctccataa cttctaaata gttttcatct gtgatcttga tagtttgctt atccccatac
    18061 ttttctttca actcattcat ttggtctaag tagtctgatt tgttgaaata aatactggta
    18121 tccggcttta agtattgtgt ctgcatctcc ggatccccta ctgattcttt acttactggg
    18181 aaattaaatc ctttggcttc tacgatcgta gtgtcgagac taactgttgg aaacaacgtc
    18241 cccacgatta ctggcaaagc tagcagtaca taagcgattc cacgttgata aggttttgac
    18301 aacccatggt catgatcgtg ctcgtgtgcc ttttcttctg cttttccgtt tttgacccac
    18361 aaatacagct gaactaaagc caaaagagca gataaaatca ttgaaagaat agctaagtag
    18421 cgataatgga cattgatata ttgatcgagt ttgccagaaa cttgcaagta catcatcaat
    18481 tcgaaatacc cagataaaat caaaaaccgc agcatatttt ccctcctaaa taaataatgt
    18541 gaatccaata acgctaaggg caatcagtcc gatcagcgat aaaataaagc gtcctgtaaa
    18601 atatcgtttc atcatcagta gatttttgat atcgaccatt gggccaaaga ccaaaaaggc
    18661 agctacaggt gctgtgccga acagacttaa caaagaagat cctataaacg catctgcttc
    18721 tgagcaaaga gacatcgtaa aggccaataa cagcatgatg ataatggcta aaatctttgt
    18781 tgagccgagc gttagcataa ttctagttgg taaataagtc tgcatcgcag ctgcgattaa
    18841 tccgccaatg atcaaataac gacctgtatc aaaaaattcg tcgattgaat gtgtcaacac
    18901 atgcccagtt tgatggatca gctgattttt tggttcattc ttctcacttt gttcttcttc
    18961 atggacatga tgatggtgat tttctgctac tttagacgtg attttttctt tcaatacagc
    19021 gtctttttga aaataggcaa gccagacacc aatcacaagg gcaacaaaaa agctgcctat
    19081 cacccgccag cttgccatct gccaagaatt gccaaatgcg ataaaagtgg aaaaaatcac
    19141 gattggattg atgatcggag cagtcagcat aaaagcaaac gctgtgtgaa ctggtacgcc
    19201 ttttttaaca aattgatgaa cgatcggtac gatgccgcat tcacatgaag gaaagaaaaa
    19261 tcctaagatc gaaccagtaa aaatagagaa gatacgattt tcaggaagcc atctcttcac
    19321 acgttctggg gtcaaaaata cttgtaaggc gcctgagata agacagccta ataatacgaa
    19381 aggtaatgct tcaataacga tcgataagaa aatcgtactc atctgcaaaa ccgaatttgg
    19441 aataaaagaa aacatgagtt tcctcctttt tatttctagt tcattcgctt tgcaaatata
    19501 cgcttttatt caaaaaaaac aagttgctct gtaaattttt acacaactct tattttttac
    19561 caaagcactt caattgactt tttctgttat tcccattaaa ttaaggtctc atacatatca
    19621 cttctatcat aaaagggaga ataaaaatga aacaaaccac taacttgact gaagttcaag
    19681 acatactgca acagtcatcc gttgccgtca tttatctttc gatgcctaat tgcagtgttt
    19741 gtcacgctgt tcgtccacga ctagaggaac ttctcacaca ttatgatatt ccggcacttc
    19801 atttggatgc atttgaaaca ccagaagtag ctagtaaatt tgaagtgctg actgcgccag
    19861 ttgtcctgat ttttcatcaa ggaaaagaag tctttcggca agcacggttc atcgacttta
    19921 aaaaaatccg ttatctacta gatgaactga cagcagaaga tgattccctt tcttatgaag
    19981 aaatcttccg aacaaaataa tcgttgtcca aacagaaaaa agcgattgaa caagtgaaag
    20041 ttttgccttc atttgttcaa tcgcttttta tttttattct gctgtatttt cggaatgcgc
    20101 atttgcgtca gaatgcaaga aatagatcaa ggtttgcaat tcattcgtca aatcaacatt
    20161 ttggatcaat acatctgacg gagcattcaa tcgagcagcg gtaaagttca agattccttt
    20221 gattcctgct tccgttaact gattgactac ttcttgtgct ctttcagcgg gtatcgttaa
    20281 aattgctact tcgatttgtt ggatcttgat ttgttctgac atatcttcca ttggataaac
    20341 ggggataccg tctacgatgc gcccaacgat ttcctcattc acatcaaaag cacaactgat
    20401 acgtatgcta ttactttgat ggaatttgta ttttagtaaa gcacttccca agttccctac
    20461 accgatcagc gcaacatttg tcaattgatc gtcgtttaat gtctttgcaa aaaagtgcat
    20521 aagatcttct acatcataac catacccacg ttttcctaat tcgccaaaat aagaaaaatc
    20581 tcgacggatc gttgcactat ctacttgaac ggcttcactt aattcagttg aagacacttt
    20641 tttctttcca gcattattta aaatccttaa atagcgataa tacaaaggca gtcttttagc
    20701 tgtcgccttt ggaataatat gatctttcac gaaatgacct ccacgtattg tctaattaca
    20761 tctttgattt ctccatcata gcagtattta taggaaaaaa tcaattccat tgctcagata
    20821 ttgtgaaatt ttattcttta ttcatttatt tatcatttct gcaaatctcg cagtataatg
    20881 gaatttatgg tagactacta attgaaaaat agttttttat ttgaggagaa ttcacaaagt
    20941 agaaaagagg attccatgat attattacaa gccaatcaga ttgctcgcca ttttggtgca
    21001 gaagtcttat ttgaaaacat acatttagaa atcagtacag gcgctcgtgt cgctttagtt
    21061 ggcagaaatg gcgctggaaa atcgacttta ttaaagatca ttgctggaat tgaagcacct
    21121 gatgaaggaa agatcgctaa aaataaaaca gcgactctcg gatacctcgc tcaggacaca
    21181 ggacttgatt ccaatgaaac agtttggaac gagatgctga aagcttttga acaagttaga
    21241 caaatggaag agcggatgcg cgagctagag attttcatta gcgaaggtac gccagacaca
    21301 cctgcttata gttcttattt aaaagaatac gaccggctgc aacacgattt ttcagatcga
    21361 aacggctatg gttatgaaaa tgaaattcgt tccgtattgc atgggtttaa attcgattct
    21421 tcattttatg atcagaaaat cgatacttta tcaggcggac agcgcacacg tttagcttta
    21481 gctcgcatgc ttttgcaaca ccctgacatt ttgattctag atgaaccaac gaaccattta
    21541 gatatcgaga cactttcctg gcttgagaat tatctgcaaa gctatactgg tgcattattg
    21601 attgtttccc atgaccgtta ttttttagat aaagtagtca atgaagtcta tgaattaagc
    21661 agaagaaaaa tgcgccatta caaaggtaac tattcgaaat atctagattt gaaagcagaa
    21721 cagttagcaa gtgaatggaa ggcttatgaa aagcagcaaa cagaaatcca taaattagaa
    21781 gacttcgttg ctcggaacct tgttcgcgcc tctaccacaa aacgagcgca aagccgcaga
    21841 aagacattag aaaaaatgga ccggctggat cgtcctcaag gggatgaaaa acaagcaaac
    21901 tttctattca gtatagaaaa gccttctgga aatgtagtct tgcaaatcga agatgccgct
    21961 atcggatatg ataatgtcac cttatctgaa ccaatcaatc tagatatccg tcgtcaagaa
    22021 gcgattgctc tagtaggtcc gaatggtatc gggaaatcga cgttgctgaa atcaatcatt
    22081 caccagatcc cttttatccg tggaaaagaa acgctaggga caaatgtcac catcggctat
    22141 tacgatcaag gtcaagctga tctgcataca aacaagacga tcctagcaga attgtgggat
    22201 gagcatccta ccactccaga aaaagagatc cgaagtgctt taggtgcttt cttattttct
    22261 ggcgaagatg tagaaaaacc aatccctctg ctaagtggcg gtgaaaaagc acgggttgct
    22321 ttagccaagt tagcgatgaa caaagaaaat tttttgattt tggatgaacc aacaaaccat
    22381 ttagatattg acaacaaaga agtattagaa aatgcattga tcgattatga cggcacactg
    22441 ctttttgttt cccatgaccg atatttcatc aatcggatcg cgacaaaagt cgtcgaactc
    22501 tctgaaaatg gcagcaaagt ctatctagga gactatgatt attatttaga gaaaaagcag
    22561 gaagaagaag aaatcgccga attgttggca caagatgagc cagaatctgc tcctgctccc
    22621 acgaacaaat ctgattatta ccaaagcaaa gaacagcaaa agcttatccg tagccttcaa
    22681 cgaaaaatta ctcaggttga agaagaaatg gcgcggatcg atgaatggat cgatcagttg
    22741 gaacaagaaa tggtcgcgcc agaaaacctg gaagatcacg taaaactcaa tgagctgaac
    22801 caagatttag aagctgctag acaagatcaa gaaacaaaat tgacggaatg ggaagaacta
    22861 agcttggaat tagaagaata tgaaaattaa cgaaaaaacc aaaacagaaa ccattcatgc
    22921 tgttttggtt tttctttttt tattttatca aacaaaaatt ccatatttac ctttttcacc
    22981 aataagaaga ccaattacta gtcattctca ctaaagcttc taaataatag taatcacccc
    23041 aaatacaagg tgtatttacc ccattatttt tgggcttatt ataaacagac tgtgttaaaa
    23101 agccatcttc ttcttccgtt gtagcatatc tttctttcaa ttgtcgcata attttccaaa
    23161 cagcagactg gtataagttc ttttctgttt tgtctaatag acctgattct attaattcta
    23221 ataatccaca aaccatgatc accatactag atgtatcttt ttcttctctg ctagaatcat
    23281 caaagatcaa atcccaataa caaatggtat cttctggcaa ccgattcata aaataattgg
    23341 ctaatatttt gcttaaatca aaatattttt gttctttcaa ataacgataa cttaatgcaa
    23401 aaccgtaaat cccccatgct tggcctctag cccaacagga attatcacta tgaccttgat
    23461 gcgtacttcc atatcttggt tttccatctt tgacatccat ataaaatgta tgataagttg
    23521 aaccatcttc tcttactaaa taatctgctg cattttgaat atgagcctga gcagcttttt
    23581 tatatttttg atttccagtt tcttcactcg cccaatacaa taatggaaga ttcatgcaac
    23641 aatccatgat cattctacct tgttgtgaag gatcactagg atctccccaa gcttgtataa
    23701 ctcctgcctt ctcccaaaaa cgctgaagta atgtttctgc agcatcaatt gaagcttcct
    23761 tcatttttcg atttcccgtt attttataat ctgctacggt tgataaagaa tacaaaaaac
    23821 caagatcgtg atgattagtg ataatttgac agtcaatcct gtggataaaa tctatatctg
    23881 ctttttcagc tgtttgttga aataaaggat cacccgtctt ctcaaataac aaccaattaa
    23941 ttcctgtcca aaatccttct gtccaaccaa tattgtctct taatggataa cgtcctttta
    24001 taggacactc gcttgggaat tgatactgac tgttactgat acgtttgatt aacctctccg
    24061 tgtgtctgcg acaacgctcg atctcattat tccattcttt ttccattaat tctttataac
    24121 attcatttat ccatttttct ggatgtatta tctcttcaaa catcacttta tcaagcattt
    24181 ccccaccagc ctttagcata attttagtct ttttttattg tttttatttt ggatagttag
    24241 cccggttgtc ccatcaaaat caattttggg acgattgttc catacttcta aactataatc
    24301 ccgatcttga tgagcaacca ctcctgttcc gagccaatgg gttccttttc caaatgtacc
    24361 ctctaatcca ggaataaaag tgttttccca tgtcatcaag tttgtattgg gcaaacccat
    24421 aatagctgtg gattttcgtt taatagtatc gtcacttaaa cagataatac ctgaaaagcc
    24481 agcttcactc accctatagt tttccttgtc ttcttctatg attattcctt ctttctcagg
    24541 agaacattca atagcaaacc ctgtctcata tagaacatat tctgtatcta attctacttt
    24601 gtgtacgcga atctgccagc cttcaaaagg aataagccaa gttctgattt ttgcctgtaa
    24661 agtaggttcc catgtagagg caagtacctc tttcttacat acaatgtctc gtacattatt
    24721 tcgaacgatg aactgtccat aggttttgat gctctcattc ttaaaactgg tcgtgatata
    24781 tgtgtccgct cgctgaatcc ctagcattga atccattgcc atttctgctt tcaattgatt
    24841 cgctcgcggt atcgaaaaac caaattgact agaataagca aattttaaat atttttcatt
    24901 ggtcaatgta tggaaatttg gccctaattg tcccgcattc aaaaaaaatg tatgtccatt
    24961 atcatgttgt atgagcaaat tggcttctga aagaagttta gttccttcac gaataggcat
    25021 aggcatttct ttagccgtcc aatactcatg gtcttcaggt agcgccaaca ataaaaaaat
    25081 cttattcagc cataatggag ataacgtact attatagggt tcagtcaatg tcaattgagg
    25141 gtaggtataa ccaatattca ggataccttt ttcatcaaat atttcttttt gcatccacca
    25201 tcttatattc cgattgacta accccttgat ttcacctaat ttaaaaggca aaagatcggc
    25261 ccacaacata gctgaccaaa agcttgaaac tgcaaaacga taaatcatgc ttcgaccaaa
    25321 aggcacattt gcaccatctt ccgcaaaaaa atgaatatag tctctagaaa aatcaatagc
    25381 tcggttctta tatatctggc taatgggctt ttctggttct agtacgctat aaatcaaacc
    25441 ataataatga aatgcaaaag gattataata atcttggcga cctcttgaac tgtctcgata
    25501 ccagccattt tgaagataac aattttctat attatcaaat gcttctttca gtgctgattc
    25561 tttaactgga taaccaaatt tttggataat tgttccgaca attatcttaa aaaattgcca
    25621 attaccatct gcacattcat attcaaaaat ttgcgagaac caatgaataa tctggctttt
    25681 ttctcctgta tctaattttt tccataataa ttgttcatga tgatataacg ctaataacat
    25741 tgcgggcatt tctaccatac gctggtctct ttcatgtatt tctccccaat aatcgggatg
    25801 ggaaggatct gttccagctt ttattcctga tagaattaat ttcaaccatc gttcatctaa
    25861 ttggtcaatt gcgggccccg ctccccataa aacccgagag aatccttcca ttcctgcaat
    25921 tttatttcca tatcctaccc cttgatgtat ataatcaatt tgtgcgccac ttgctcgata
    25981 aaacggctgg agtggttgat ttatcttttt aaataagtca aagtaatcct gtctggtcct
    26041 taatagtggt actggatgtt tcattgtatt ttctcctctt tttactacca aatagctaat
    26101 tccgactgtt ctaatcgaag taagccttca ataaaaaaat aatcagaata gatcagtggc
    26161 acattataag tcagttctct atggtatgct tctgctccgc ctccaatgat cccatcttca
    26221 tccatattcc aatttgcata gtgcttttct gtcttttgga gtatattgat agcagcttca
    26281 tgatacattt ttgatcgtac agaggaaaca tatcctgcta attccagaag accgcatgca
    26341 gcgcatactc cagcactggt atcaatattc gaatctttta cagcaaaatc aatgagagga
    26401 atataaccag ttttttcgat tttctgaata aaatttactg ctatcttttc tgctatagct
    26461 agatagtacg gattttttgt gtaacgataa cttaacgcga atccatataa agcccatgca
    26521 tttcctctgc tccaacaaga attctcattg tatccttgcc cgccaagtaa ccgaatatat
    26581 ttccctgatt ctgcatcaaa ttctgcgata tgcccggttg atccatcttt cctcactaga
    26641 tacttagctg ttgtatctgc atgctgccga gcaattttag agaacctcgg atcaccagtt
    26701 tccctcgaag cccaatacag taatggtaaa ttcatcatac tatcaataat catccaacca
    26761 ggtttatggt cattccatgc tactaaatag ttccctgaaa tattatagcg tccagcaagt
    26821 accgtagctg catgtaaccc tagttgtcga ctatgtttgt tttgagactg ttgataatgt
    26881 gcaatagccg atggtaagaa taaaaaacct acatcatgat gaacgtctga aaaatggtac
    26941 agggcagatt ctaataattg ttcttgttgt attgctgcct ctttgaactt ttctcgtttt
    27001 gtcttgtgaa agagctgcca taaaatacca ctccaaaaac cattggtcca ccagtcgatt
    27061 cctctgtcct ttattacgtc tgtatatttt ccgttgtaag aaatatatgg aattttattc
    27121 cccattctgt ctaattccgc atctatcttt tcagaagcta cattcaaaat ttttcttgac
    27181 cattccttcg tctgttcatt catggatatc ccgccattct tttaattttt atgaatgtgg
    27241 agttgctcct agaacgaact agatggttaa cattcgttat tttttttact tatttgcagc
    27301 tccaatgtca ttctccttaa atttagactg cgcccacaca taaatcaaga ccattgggat
    27361 cactgaagtt gctaaaatta gcataattgc gccataatta attggctcac ctgtactaga
    27421 aaccgtcata tttttgataa ttaagggaac cgtatattta tctttatctg aaagcatgac
    27481 taatggaaat agatattgat tccaacttcc cataaagata agtaaaccac tagtaataat
    27541 cgtaggtgat aaaatcggta cagcgatttt cgtaaaaatc acccactcat tggcaccatc
    27601 gattctggca gcctccatca gtgctgtagg aaattgactg ctatattgtc gcatcataaa
    27661 cactgaagtt gtactggcaa tcgaagggat gatcacacct gcataagtat tcgataatcc
    27721 taaacgactc ataatgtaaa ataaaggaat caatgtggta aaaaaaggca ccatcctaga
    27781 tagcataact gtattgaaca acagtttatt ccccataaaa cgatactttg ctaatgcata
    27841 acccgccatt gtagaactgg ctgtagctaa aactgtactg attacagcaa taacaatcga
    27901 attccaaata atcaagggat aattatatct cgccatgatg gcttgccagt tttttaatag
    27961 catatcccca aacttgaaat tgattccgcc acttaaaatt tcttgattac tttgcgttga
    28021 agctacaatc atatataaat atggcatcaa aaatattaag gcaccaaaca caataatgac
    28081 gtacgtaaaa attctgcttt gtatcttttg tttagtcatt tttatcacct ccgaatttaa
    28141 attgaatagc cgataatata acagatacaa acaccatcgt ccaggcaata gcagaggctt
    28201 ttccaaaatc aaccatttca aaacttgttt tatataaatt gactcctacg accaaagctg
    28261 aattttctgg tccattggaa gtcccaaaga atatatttgg gatattgaaa ttacccaagc
    28321 cattgatagt ggctaaaact gtggccatta aaatgattgg ctttagcatg gggatcgtta
    28381 ataaaaagaa ttgccgaaat ttcgatgctc catctatttc agcactttcg tatatctctt
    28441 tagaaatccc ttgaagacca gctaaaaata aaatagtgtt atatcctaca ctaagccaaa
    28501 tcatcgtgat gatcattgat attcgtatcc aaaaaggatt tgttaaccac tgtacaccgt
    28561 taattcctag cgcattcaaa aatccattga ataacccagt cggattgaaa aaagtcatga
    28621 atacggaagc tacagccacc gttgatgtaa tggttggaat ataatagaca gttctaaaaa
    28681 atccttttcc ttttaactgt gctgaattca ataaaacagc aaagtaaata gctaatagca
    28741 tcgttattgg aattgatcct gccatgataa tcaaaacatt cgtgtaagat ttaataaaca
    28801 atggatctcg gaagatagct agataattgt caaatccaac aaattcaaat gagtagccaa
    28861 ttttcataaa actaaaagca aacgagataa tgatgggaat caaaatcgtc acaataaaga
    28921 aaataacaaa aggtgtgacc aatccataag cacttttttt atgagacgta tctgttgctt
    28981 ttttcttgct gttctttatt gtcttgcttg gtaacgaaga ttgcatcatc gttaagtcct
    29041 cctaatattt tttaatcacc agttaatttt acgccgtact tatgagcaaa attttctgct
    29101 tcttttagat atgaattttc aaaatcacct gtttgccaat agttatatgc agcggtagtc
    29161 aaataagacg tagcatctga ataagtggct ggtaaaacag tatttgatgt attttcattg
    29221 attttattca atagttcata gtatttttgt cctccttagt agtcaaactt tttctcagct
    29281 gcttctgttt gataggccaa tgagttagat gtagccacgc ccagctccag tgcgttggct
    29341 aagcattctt catctgtcag cataaatgta agaaattgtt gtgccacttg tggatttttg
    29401 gcatctttag ggacataaaa acttgatcct cctgatactg caccttttcc tggattttct
    29461 tttgaaaaag gaatcagtgg agccatgcgc catttgtcag atgcatcagg aaaattcaaa
    29521 gacatattcg tagcatacca gccgccagca acaaacattg cagattcttg aaatgctttc
    29581 tcagcatctt gtgcaccgta gaaatgtaca atatctgagt cgatcatttc tttgattaac
    29641 tttgcagcat gtttcgcttc tttagtattc agacggatat ttccttcttc atcaagcaaa
    29701 gattgattct gctgggctag catgttgata aacaattctt ggtccccaga ttctggcaag
    29761 gcaattccaa aactaccagt tttttctttt aatgcttttg ccacctggat atattcttcc
    29821 caagaactga tttcttcaaa atctacacct atttcagcaa atttttttgg ttgataataa
    29881 caaagtgctg gggtaaaatc actagcccaa ggaataatcg tttcattact cgtttgttga
    29941 cgcaaaatat tcaatttttg atcataaaac tgatcgccat atttgtcata aaatccatat
    30001 tcatcagcac tataaaaagc atcttgaaat ttttccagca cacctgctgc tgaagtgtct
    30061 gccatggaga taatatccgg catatcttcg tgtgttacca attttggggt gatcatttgt
    30121 actgttgctg ttcccgaagc tacattcaca atttttaagt caatatttgc tccagttttg
    30181 cggttataga tttttgcagc attttcaaca tagtttgtca gtttgccgtt tgcgacatat
    30241 acttctaatg tagtggcttt ttttatcatt ggatctgcga tgtttgctgt tacttcttcg
    30301 ttagtttttc cacatgcact taagctgaat aatagggtaa tgtttagcaa agctatcacc
    30361 aatttgtatc tttttttcat gtctatccct tctttctttt caagttctta tataaaacgc
    30421 tttcacttat gtatattaac ggaattagta acacaaatat ttatataaaa aaatatttta
    30481 cttgtcgttt tggcttttca tttttgttat aatagtcatt aattataaat agaaagcttt
    30541 ttatataaaa agagaaagga aagtggttct tttgttaaca aacaaccaat cctccaatct
    30601 tgtcaaaaaa acactaacct attccataga tacccatctt catttatctg ctgctcccta
    30661 ttttcgacta ctaataaatg aaagcgctaa tttatatgct gaatttgcac ataaatctat
    30721 agaactagat aatccttccc ttttattcat tgataaacag caagaagtcc aaatcttttc
    30781 tactcaaaag gaaacacaaa cttttatcat tatccagttt tattttgatg agcaattatt
    30841 agcacatatt acgggacaat ctttttctat agatcaagaa ataacatcta tcattacttt
    30901 tctgaaaaat gaacagttca aaattgatta tctaaaacat agtaagccag ctatttccta
    30961 tgatcaggaa atcaattctt ttttcatact atgccaacag atgagcattc atttgctttc
    31021 cttattagtt acttattgtc tgcaaaaaat tcaattgtct tccttaccaa ggcattatca
    31081 acaggaactt gctttattga caataccttc aaatgagaaa gtcattccta aaaaaaagca
    31141 tattctttat tcagatgaat tagttgatcc aatcatacga tatttagaag aacatctttc
    31201 agaaaatttt ttgcttgaac aattagccca aatttttttt atcagtccag ccagcttaaa
    31261 aaaacatttt agaaaagtga atggaaaaag tgttattagc tattttaaag aactaaaaat
    31321 ggaaaaagca aaacgtctcg tgctagaaaa tgaattaacc tatacagaaa ttgcagatat
    31381 attaggattt cattcgatcc atcatttttc ttcagctttt aaaaaatata cagggttatc
    31441 cccttcaaag tattatctat ccttaaaata gaaaaaaatt tttaggtttt atccacaaat
    31501 tatttctcta tattttctgt ctattcaaaa taaacaataa ttttccggca caattatttg
    31561 ctgtttttta ccataacata gtacgatcaa cgtagaaaag gagatgtttt tatgaaagtt
    31621 gttgtcattg gcggtgtagc tggcggtcct tcatttgcca ctcgtttccg tcgattgaat
    31681 gaagcgcacg aaatcattat ctatgaacgc ggagaaaata tttcttatgc aagttgtgct
    31741 ttgccttatt atttaggagg tgtgatcact gaccgtgact cgctgatcga acgtacacca
    31801 gaaatattga aaacaaaaaa caacatcgat gtctttacta aacacgaagt aacagcaatc
    31861 gatccttcta ctaagcgatt aacagttaaa gacctatcca caaatgaaga aataaaaaca
    31921 gattacgata agttgatcat ctcttctggt gctagaccag attatccgga tattcccgga
    31981 gtttttgaag cagaaaacgg ctttgtcctc cgtagtgtga cggatgcgga tcgaatcaaa
    32041 tcgttccttg aagaaaaaaa tccacaacat gtcgtcattc ttggtgcagg tgttatgggt
    32101 ctggaattag ctgagaattt caagcatcgc ggcttagacg tgactttaat cgatcaattg
    32161 ccacaagtcg ctttccctta tgatccagaa attgctaatt tagtttatga caaattgctg
    32221 aaagaaggat tagccgttca tttagaaaca agagttactg aaatccgtga taaaggtcga
    32281 gaaatagtat tatcagatgg ctccgtcctt tctgctgata tgctaatttt tgctgttggt
    32341 gtttctccga agaatgaagt ggtgaaagca accggcatac aattatcaga tacaggtcag
    32401 atcattgttg atgaccagtt acaaaccaat ctgccggaca tctatgcgat tggcgatatt
    32461 atcgaaacga ctagtgtagt gactggtcag ccgatccaaa gtatgctttc cagtgcggcc
    32521 aatcgtcaag gacatatgct ggcagatatt ttaaatggta cgcctatgcg ctatcgcgga
    32581 tatattggtg caggtgtcgc aaaaatcttt gatcatacag caagttatgc gggaatgaca
    32641 gaacatgaat taaaagcatc aggcataaca aattataaaa ctgtttttat cactcccttt
    32701 gaccatgcct atttctatcc agaagctaca agattaaatc taaagctgat ttttgatgca
    32761 gatagcggtc gtattttagg tggacaagca tttggagaaa aaggtgtcga taaacggatg
    32821 ggagaacttt ctgtagcaat caccggaaac ttgacagtct ttgatttgcc tgatttggag
    32881 ttgccttact ctccaccgta ttctactacc cgtgacccgt tgaatatagc tggttatgtc
    32941 gcaatcaatc aaatgacgaa tatcgtagaa acgatcaaag caagtgatat acccgaaaac
    33001 gatttgaaag aagcgttctt tttagatata cgtgaaccta ataaagcacc ttctggcagt
    33061 atctcggcaa caaaaaatat tccaatgaat gagttacgag atcgaatcaa tgaaatccca
    33121 aaagataaaa aagtttacat tactttcaga agaggattga atacttatac ttctgcccga
    33181 atcttggcag gtttgggtat caaagcgatt ttgattgaag aataaaaaaa cgaccgcggt
    33241 gggtagccgc ggtctaggag ttatttttac ttgaggagta aaaatgaaaa agtatatagg
    33301 gttgttggtt ggtatgtata tagaatagaa gataaatgtg aagaaattgt gcattatttc
    33361 ttcacattta ttaggttata gtttaagaaa gtttaaacat tgcgcaattt aattatttta
    33421 gctgtttctt ttcataaaaa aacatgttgt gactctgaga caaatcatag tccatagtga
    33481 tgtctctaga gtaactacgc ctaatattac gaggcatcat attaatctat cagcactagt
    33541 acctaaacta gcatcccttt cgaatatttt ttcttatata ataaagtttg ctttcactcc
    33601 tctaatctca ccaaatcgac tggcttgcgt tgtgtgatac taggaactga ttggtttaga
    33661 acgacttttc tattgtaatc atatttttcg ccatcctcgt tgtcttctaa tccttcaatg
    33721 aatgatccct aatgtgtgta ttaaataatt taattttttt gttcctattt atttaa
//
LOCUS       DACGMI010000034        33039 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.035, whole genome shotgun sequence.
ACCESSION   DACGMI010000034 DACGMI010000000
VERSION     DACGMI010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33039
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.035"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            44..379
                     /locus_tag="IXT46_001693"
     CDS             44..379
                     /locus_tag="IXT46_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947608.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
     gene            complement(636..2219)
                     /locus_tag="IXT46_001694"
     CDS             complement(636..2219)
                     /locus_tag="IXT46_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947609.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLSYGNEE
                     ADRDRESTFRLLNALIFDNKEFYLNILKKEIAKYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGNN
                     NEELQNHLNSLVDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKKLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            2341..2925
                     /locus_tag="IXT46_001695"
     CDS             2341..2925
                     /locus_tag="IXT46_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947610.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            2936..3181
                     /locus_tag="IXT46_001696"
     CDS             2936..3181
                     /locus_tag="IXT46_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947611.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            3187..3909
                     /locus_tag="IXT46_001697"
     CDS             3187..3909
                     /locus_tag="IXT46_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947612.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            4040..4783
                     /locus_tag="IXT46_001698"
     CDS             4040..4783
                     /locus_tag="IXT46_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947613.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            4789..5154
                     /locus_tag="IXT46_001699"
     CDS             4789..5154
                     /locus_tag="IXT46_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947614.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDRQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            5170..5700
                     /locus_tag="IXT46_001700"
     CDS             5170..5700
                     /locus_tag="IXT46_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947615.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            5862..6092
                     /locus_tag="IXT46_001701"
     CDS             5862..6092
                     /locus_tag="IXT46_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947616.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIEKCY
                     YGQHYWSEEVRENIDREYVQRIVRLPVSELKK"
     gene            complement(6296..6775)
                     /locus_tag="IXT46_001702"
     CDS             complement(6296..6775)
                     /locus_tag="IXT46_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947617.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            6895..8232
                     /locus_tag="IXT46_001703"
     CDS             6895..8232
                     /locus_tag="IXT46_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAQ4947618.1"
                     /translation="MLMVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRAVEG
                     YYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMF
                     KGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMK
                     SKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            8255..8782
                     /locus_tag="IXT46_001704"
     CDS             8255..8782
                     /locus_tag="IXT46_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947619.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            8769..9332
                     /locus_tag="IXT46_001705"
     CDS             8769..9332
                     /locus_tag="IXT46_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947620.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            9755..10492
                     /locus_tag="IXT46_001706"
     CDS             9755..10492
                     /locus_tag="IXT46_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947621.1"
                     /translation="MADRKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANHQD
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(10509..10925)
                     /locus_tag="IXT46_001707"
     CDS             complement(10509..10925)
                     /locus_tag="IXT46_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947622.1"
                     /translation="MNKKRKLSVLITLVSILTILSGILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETVTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            11317..12564
                     /locus_tag="IXT46_001708"
     CDS             11317..12564
                     /locus_tag="IXT46_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HAQ4947623.1"
                     /translation="MNMKKNSLGMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETAKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTETDTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            12834..15224
                     /locus_tag="IXT46_001709"
     CDS             12834..15224
                     /locus_tag="IXT46_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HAQ4947624.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     KFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGAFKQEGITVKDDGQTFEYTATNTLKKGVVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGISVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDRNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            15273..17108
                     /locus_tag="IXT46_001710"
     CDS             15273..17108
                     /locus_tag="IXT46_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAQ4947625.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANRTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            17183..18040
                     /locus_tag="IXT46_001711"
     CDS             17183..18040
                     /locus_tag="IXT46_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4947626.1"
                     /translation="MKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNSYK
                     EKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGELVG
                     EILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKYFT
                     DLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVGDN
                     SHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKIVA
                     KRRGMKNEE"
     gene            18030..19139
                     /locus_tag="IXT46_001712"
     CDS             18030..19139
                     /locus_tag="IXT46_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4947627.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKPETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVLGALASLKVLILLIKEFRKA"
     gene            19478..20278
                     /locus_tag="IXT46_001713"
     CDS             19478..20278
                     /locus_tag="IXT46_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947628.1"
                     /translation="MVEISKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETLKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLMGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYADDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            20366..21172
                     /locus_tag="IXT46_001714"
     CDS             20366..21172
                     /locus_tag="IXT46_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947629.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQFAEEKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            21404..22273
                     /locus_tag="IXT46_001715"
     CDS             21404..22273
                     /locus_tag="IXT46_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAQ4947630.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAINSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            22293..22640
                     /locus_tag="IXT46_001716"
     CDS             22293..22640
                     /locus_tag="IXT46_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947631.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            22653..23915
                     /locus_tag="IXT46_001717"
     CDS             22653..23915
                     /locus_tag="IXT46_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947632.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            23995..25371
                     /locus_tag="IXT46_001718"
     CDS             23995..25371
                     /locus_tag="IXT46_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAQ4947633.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTAMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMIIKLVNGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAESRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANSSSKEPSIEKKSTFALKLEKNKEEKEKQGAKTLEKLQAEKLEKVLKALDK
                     ADSEPQTSNNTNNEQPISSKTKPKTTDPKVSVNVTITTDKSEKKQVNGTTSPIMQKML
                     KAKKQVHK"
     gene            25368..25997
                     /locus_tag="IXT46_001719"
     CDS             25368..25997
                     /locus_tag="IXT46_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947634.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRTKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            26016..26495
                     /locus_tag="IXT46_001720"
     CDS             26016..26495
                     /locus_tag="IXT46_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947635.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            26997..27050
                     /locus_tag="IXT46_001721"
                     /pseudo
     CDS             26997..27050
                     /locus_tag="IXT46_001721"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            27054..27653
                     /locus_tag="IXT46_001722"
     CDS             27054..27653
                     /locus_tag="IXT46_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAQ4947636.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGETNVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            27669..28145
                     /locus_tag="IXT46_001723"
     CDS             27669..28145
                     /locus_tag="IXT46_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947637.1"
                     /translation="MPKKKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRIFEWLNTNTEQEPLRAISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSEDSKSMRDLLITYLNEHEFEQTKVKKKNKK"
     gene            28162..29064
                     /locus_tag="IXT46_001724"
     CDS             28162..29064
                     /locus_tag="IXT46_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947638.1"
                     /translation="MLFTLLGYLCLVLAFFGAIAIFVGQFQENNPIMRNIGIGIVIIS
                     LIVFGATKIFGSNDQQFGISGVDNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDDK
                     KASDDVLATIKPSQSQFEVFYTVKENNPVRKLTLVFNVDGEEYYKDVKINKASTKKIV
                     ESAKKEVATEESTTESSSTVEVELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQRINVTLFNAVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGSDLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            29137..29331
                     /locus_tag="IXT46_001725"
     CDS             29137..29331
                     /locus_tag="IXT46_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947639.1"
                     /translation="MVVNKEKVRKYVTLKIASVEYLEKRAKEEEKTRGKKVTVSELLE
                     ELIESDQTIRRAFTNRSVKS"
     gene            29436..29864
                     /locus_tag="IXT46_001726"
     CDS             29436..29864
                     /locus_tag="IXT46_001726"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947640.1"
                     /translation="MIIQKFDWKMKLGISLVILGFIIFLGIKAQKNQSTFETMSSQII
                     EECSKIYYCENKTEESNGFYYIDQPHDVVIKMESHEVNEWIQRSTNVSKKLERYSQTF
                     LSKVIFSNCKNEETSQRVASSLENLKFSVSKKEKFVDLRK"
     gene            30099..30686
                     /locus_tag="IXT46_001727"
     CDS             30099..30686
                     /locus_tag="IXT46_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947641.1"
                     /translation="MENNNDIRYFSIGERVTTVSELSKDYRDKEGTIISLKKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNDGSHSIEKAILVFPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITNKEAKVEDVLTVRELQSLIEYRNKQITNPEYLKKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDNFKKIYLKEIEKD"
     gene            30686..31585
                     /locus_tag="IXT46_001728"
     CDS             30686..31585
                     /locus_tag="IXT46_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HAQ4947642.1"
                     /translation="MWSVTLPFQPVSAPRPSARRNVADATNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQGLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            31585..32499
                     /locus_tag="IXT46_001729"
     CDS             31585..32499
                     /locus_tag="IXT46_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947643.1"
                     /translation="MNNNEKILHVLDSFEIIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKNAMELNEERRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            32551..32766
                     /locus_tag="IXT46_001730"
     CDS             32551..32766
                     /locus_tag="IXT46_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947644.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
BASE COUNT        12382 a         4553 c         6486 g         9618 t
ORIGIN      
        1 aatttcctag gaaaaatagt taacataaaa ggaatgaatt gttatgaaac aatatttaaa
       61 tgaatggaaa gcgatagagg ggtcattagt aacgcaaaga ataaaggaat tacctgattg
      121 cttagagaag gatcatttgt ttcaaatacg agaaatgttg aaaaaagaac agtttgatcc
      181 agaccaattt ttagtagtcg agtatccaac tattggagtg tactgttgta accatatcaa
      241 tgatggaaaa tattttatta ttcaggagta tggaggacag ttaactcctt tctatactac
      301 atgggaaatg agtgaagaag gaatcaataa ttttccatgt gaaagcatcg aagattcaat
      361 ttcacacacc gaatgttaat tgattataac tataaaaaag gattgaacat tatgttcaat
      421 ccttttttca atgaaatgtt ttccgccatt tcattgtttg gtgcgatttc tattttatta
      481 tatcaaaata aagagagatt ctaaagaaag aagagggaaa tatataaatc aagcgacagt
      541 atatttatta ttaaatgcta ttgtgagaat ataactaatt agtttaattt gaaagtaaat
      601 atacgctata aaagtgcatc ttgtgttata aaaaattatt ttattttgtg aacataattt
      661 aacaattctt tctcggaatt gatttctttt cttaaatagt cttcagactt attaataata
      721 ttatctatta tgtctagata catatcactt ttcgattcag ctaattcata cagttttttt
      781 aattctttat cctttaattg aaaaccctga tccatagtca ctgcatttgg atatagaagc
      841 ccactataat gtttacgtaa attcacttgg aatttctgat tataaaagtc taacagatta
      901 gaaataaaag gcggaaaatt actgtttttg taaaattgat tatttccatt taggttgtat
      961 agtaatttgt taaattgctc ctgatttaat ttattgtaaa tccatggtaa tacttccata
     1021 tccttatctg ctaacctgaa tgaactagca tcggtaagat gttcgatcat aaaatctatg
     1081 aacatctctt tttcaccaaa atataaatat tgattatata ttgtttctaa tgttgaagat
     1141 ggtagcgaag aaactctcat tttttgctgg agtataggat caactagact atttaagtga
     1201 ttttgtaatt cttcattgtt gtttcctaga actgcaaggg aacgtaaacg gtagtaatat
     1261 tctatttctg ttagtacttg ttgtttcggt ttaaaatcat ttattgatat ttgtaaattt
     1321 tgaattgtct cgtctgaaaa atcatgttgt aattctggat gggtagctat aaaagtaagt
     1381 aaaaagaacc cttttgtata cgtgatctgt tgattttcac caagtgattt attaatttcc
     1441 tctcttgatt cagctgtgaa cctatacttt gcaatttctt tttttagaat atttaaatag
     1501 aattctttat tatcaaaaat tagggcatta agtagtctga aagtactttc cctatctcta
     1561 tctgcttcct catttccata agataattga aaaacaaact taaaggctgt cttacatagg
     1621 ttttctttgg ctttttcgct tagtttattt agatagctat tttttagtgc agagtgaaat
     1681 tcttcaggtg taacagacat agcatgtatg cgacttgcat attgtataat ttcgatcgtt
     1741 actttttttc ctaatattgg attttttagg aatataattt cataggactt ccgtataaca
     1801 tcctgacaag tttcttttgt tatatctctt aattcccaag tattaccgtt gtaagtgact
     1861 acaggatgag ctgaataatt tctttgatcc ttaatatatt ttaaatcctc atattcatag
     1921 ctatcaatta gctcagttga actataagct ttttctagta gttccatttc ccattttgga
     1981 gagtttggat cactttttct tagtctagct atatcttcta aaattttctt agaagtatta
     2041 tcctcgtaaa tatttgctaa atcagataat ttatcaatta aatctaaaat aagcgcactg
     2101 taattgacag ctattgcaga acgataattt ccctgataaa aactacttct aacttcttct
     2161 aataatggaa taattctagg atttttaact ttttttattt catcatctaa tataaacata
     2221 taaatctcct ttttttattt gtatgacaag tttaccataa aaaaaaatta aaaagcgaga
     2281 catatttatg ttgttgtgtt atcataataa cataaatatg tagagtgaga tgatgaaaaa
     2341 atggatttga aacaatcgtt ttacatctgg ttatatcctg ataatcctat gtcaataatg
     2401 gctgatattt ttgtagttag catcttattg tatttatttt atctaatttt ctttcacaat
     2461 ttaatcgggt acatgattct tgattggaaa ggaatgttcg atatagaaag aaaaccattt
     2521 gctaacaatc aaacctatac cgtcttcgaa agtggagatt gggaagaaaa tgaagttgat
     2581 gtgatccatg aaattggatt agctttatca ggaatacaag atgctgatgt tttggtatca
     2641 atgacaacgg atactggata caacgcttat gaggtatttt atcttatgta ttttatatgg
     2701 cgtgatggtc aagaaattat caatggtcgt gctgaaaaaa caatcaattc taatactgaa
     2761 atttcttttt gtatgggtga aggggaaatg attgtatata aagatgggtc agcaaacatt
     2821 aaaacagcct ttggtgatat tgaaacaagt attaaggaac ttagggaata tgtgcagaac
     2881 ccatataatt ttcaatattt agcaggaaga ataaatttag tttaggagta aaaatatgaa
     2941 aaaaattata aatcaaccaa caaatcactt gataattgaa ggtgttattt tcgtaacaat
     3001 gtattttact gtaggaaatg gcatctcaaa tacaatcatt caaaaaaatc cacaatacct
     3061 attatttagt ctttatgctt ggattgtaca aatggtttgg gtttccatat tgatgctgtt
     3121 gttttattgg atagtacggg ttattctttt attgttaaac aaaagaaaaa aggataggtg
     3181 aataaaatga aatcaactaa attgaaggtt gtattgttat cgacagcagc attaataacc
     3241 cttacagcat gtggtacaac taatagtgct aataataaca aagacacaaa gtctagtagt
     3301 acgatggtta ctaaaaacag cactacatcg gcatcaacaa caatgtcttc aatgactgaa
     3361 aataatgctg aaaagtatca aaaatacgaa gacattaata aaggtcaaaa gccggatgaa
     3421 gtttataaca actttattaa tacagtaaaa aatgatgaaa attatgggaa tgatccattg
     3481 caaaataaaa atctgactat cgttctttac aaacctgatt gtccagattg tcaaaaagca
     3541 gaatcaaaaa tcatgcaaga aataaaagaa ggatttagtt atgctccaac attaatgcat
     3601 gatattacca taaataaacc agcttacgag tattacgcag ttgctgtaga tattactgat
     3661 ggtgtacctg agtgggtaca aaacattcct ggtctggctg atgagaacaa tcaatatcat
     3721 acgccaacag ttgcagtagt aacaccaaag aaagttaacg gcacactata ctgggatgta
     3781 atgggaatga caacaaatac aactgatgaa atgattgaaa gtacaactaa atattatatg
     3841 gatttgggag catataaatt atatcaacaa tcagagcctg ttatggacga tcaatccaaa
     3901 gttaaataga tctttagggc gtaagcccta tttttttaaa attaagtgat aacaaataaa
     3961 tgatttctga aacaaacgtt cttactcaac tactcgaaac acacaagcta attaactaga
     4021 ttataaagga gaatgcgtaa tgaaagaaat cagtgcaaat gaagctcata ttccgcaaaa
     4081 gaatcaggtt ggtatatata aggtgcttca tggtgaagga atttataaaa tacagttact
     4141 taccggttac aataatggtg caaatgggaa gtggttaaag gcaacaagta ttcgtgaact
     4201 tagaagtgaa gtagaaaaaa ttaggcttgg tctcacaagt gaagaaatag ctaaactgaa
     4261 gggaaataat tcttttgtaa ttgaaaaaga aaaggaaaaa catctacttt atcgtgagct
     4321 gaaaattgaa gaatactatg aaattgattt acctgaaaaa ttaagaatta ttgatcaacg
     4381 ttcagaagaa aaatggaaaa ctgaaatata tccaagctta aatgactaca agacatcagg
     4441 aaagcccatg tataactaca caggcttttt aacctacaca caatacaaat atgcctttcg
     4501 caaattaaaa ggcattaaac aagctgaaat tgctctgtat gagatgaaaa aagtggatag
     4561 attgaaattg attcaagatt tagtgcaaaa tacatggaat caagcgattg tcgagctaga
     4621 aaaagaaaat gggaaaattt taactaataa atatctgatc gtaaatgaaa ttgaagaatt
     4681 aattggttta ttttcatgtg aaaaaggtga agtcttcttg aagtcatcac caacctattc
     4741 aattttggac agtccgtatc agtttataca ggcaaggaga tgagttagat gtctagcttg
     4801 aaagatgact atatccaagc aaaacaagag tatgaaaaaa tacagatgtt gaaatctgag
     4861 aaagtcgaat tatttttaac acaaaaatta gcagaggatc atattgctaa cttagatgct
     4921 aaaactttag aggaatatga tcggcagttt aatcagatac atcacaatat cattttgctt
     4981 gttgagcagg caaagcgaag gtttgaaaaa gcggaatatg atctattaga tcaaggaatt
     5041 gtatgcttgg ataagggatt gcgaagatat tatggtgcag agttaaaaaa gcaaaatgta
     5101 gatagaaatg cactaaaaca tgaaatctta gaattgataa tgcaacgaat ttgaagggat
     5161 agaaagcaaa tgtcacaaaa cattagtgct gtaaaacaat taatagaaga agatttagag
     5221 accacagttc agagattagc ggaacgaatc cattttgcaa attatcaaac catctctaac
     5281 tggtcaagca ggaacagaaa tccggaagaa attccaatga aattttttta tcgaatcgga
     5341 aaagaatatg gtgttgatcc gataaaaatt ttcgagaaga ccatgattta ttactatcat
     5401 ggaacaccta acgaagtgtt agaacatctt ttggaagagg caaaagaaaa atcatcaata
     5461 ttagagctat cgcaaaatga caaagttatt caagtgaaat gcgttgatcc aacaggaaag
     5521 attattgtcg gttttgatat tgaaagaaaa tccaaaatag attttattac acaattaaaa
     5581 aagataaata atttagatat tctaacgctt agaccagatc atgaacagtt gtttatgagt
     5641 tttaaaaaac aattgaaaga aatacaaaaa agatataaca aggtgtttcc taatgcgtga
     5701 aaagctcaaa gaaatcagag ttttttggat aattaacaaa gaatgtatca tcttatatac
     5761 tcttggattt cttagcatga tcttgttttg gtggttatat ttaaaacagt aattggagag
     5821 ggtcaagagg atttttatca agataaggat gtggaaactg catgtggaat aatagattaa
     5881 aaacaggatt gttattaata gttatttcct gcgctatgat gattggtatg aggatacaaa
     5941 gggaacaatc ctattttgaa gtttctgcta acaacgtaat agaaaaatgc tattacggtc
     6001 aacattattg gagtgaggaa gtcagagaaa atatagatcg tgaatatgtt caaagaattg
     6061 ttagattacc agtaagtgaa ctaaaaaaat gatgagatta tcagcatatc ttttaatgtt
     6121 tttgaatgtg gtcacgttaa tctttgtagt aatcggtgtg actttcgatt taatggaata
     6181 gtgggaaatc tataatggaa aaaagagaca cgaatgaaca tattttttga atcaatattg
     6241 ttgatggttt ttgcgatcag cgcttaccag aaatctaaaa aagagtaatg attgtttaat
     6301 catcactctt tttttgtagg gaaattgaaa tatgtggagc ttgtattggt ttagttagga
     6361 ttgcttggct ataaggagct agttctttat caaaaccatc aaagtaggtt ttcagtagcg
     6421 atttaactga tcgctcatct tgtttgattt ggataatttc agcatccaaa tcggttgtga
     6481 gatcaggagc ttttgatgcg attacctgat tttttttatc ttccaactct cttaggctgt
     6541 ttaacaagtt gtaaaaagaa tcattttgat tgttcattcc aacgtgagtt gcaattttaa
     6601 cagaagtttc gtccgtattg tcatcaaaag aactcattgg aatatcaagt agtaacgagg
     6661 atgtttcttt tactgacttt ttctttacag cattttttgt ttttccatct tttttgctct
     6721 ttactcgaga tgtttttgga gctagtttag gtaaatcact tgttttatca gtcatttatt
     6781 agcttttcct ttctattaat ttatgttatt atattatcat aataacataa aaaagtacac
     6841 tttttggggg cgtagttatt gaaaaaatct aagagaaaga ttgccacatt gcttatgtta
     6901 atggtgcaat ttacagggat tgcaatgagt gtaatcacaa taaatccgca agtgatacat
     6961 gctgatggga tagctactta tgatgcacaa tttaactgta ctactgaagg tagtgggtca
     7021 ggaacagata gcgatggaaa cgatactgga agtggcgctg taacaggtga tgtagccaaa
     7081 aatattgaag atatttacaa atacatgaat ggagaatatg gcttatcagg tgctagtatt
     7141 gcaggtattt taggtaactg gaaacaagaa tcaggtattg atcctcgagc agtagaaggg
     7201 tattacggag atggacagag agaagttgac ttcatcaaac aatttactga tggtctgatg
     7261 ggtattggct atggtcaatg gacagctggg cgacatacag cattagttga ttggtctaag
     7321 aaaaataatg gcggttcttg gtggactaca gaagcccaat tggactttat gttcaaaggt
     7381 gatgggggat tcgtaggaat attaaaagat tatgctttaa atgcttctga tgatgtcgta
     7441 gaaaatgcag taacttttca taaaaactgg gaaatttcag ctgattccga atcagctgta
     7501 atagctgtac gtggtgaaaa tgcaaaagaa atctggaagt acatgaaaag caagggtatg
     7561 gacggtgcaa aagatgaaag taagatcaat aaaatatccg gaggttcaag taccggagat
     7621 ggatcgaata attcatcaag ttcagcatca ggaacagtag aagatgcctg tgcaactacg
     7681 gatgacgcta attctggttc tggatcaatt gggaaagaag gaaaaattaa cggtaaaaaa
     7741 ggtcaagtaa tagcgaatat gacttatgaa gaagctttga aaaaatatgg gaaagcgatc
     7801 acgctaccaa aattcaaaga accagattgg tcaacttcac cttttaacgg aatatatcaa
     7861 ggtcagtgta cagagttgac gtgggcttat atgagccaat tatacgatgg gaatcaaccg
     7921 actactggaa atggtggtta tgtatgggaa agctacaaat cggcaggagc aaaaataacg
     7981 aacaaaccaa tcgtaggtta tgggtttagt gcttcagatg gatggttatg ggctgttggc
     8041 gatgcagggc atactggtgt agttatagcg gtgtttgaag atgggtcatt tctatgtgct
     8101 aactttaatg ttccaccaac ccaagctcca acaaggggag tttcggtaac tttgattgat
     8161 ggagtggacg gatcagataa tgtgcatttc tttagcggtg taggaaaagc taaatttgaa
     8221 atcgaaaaat aaattggaat gaaggacgat atagatgaat agtaaagtga aagatacaat
     8281 tatcatttct ttgctttctg gtatgttatt agcactgctt gttggaatcc tattcttcaa
     8341 taagcagaat caggacatag aagctgaaaa acacagtgtg catattgaag ataagctgac
     8401 attctttaaa gaggttaaac caaatgaggt ggatggatta cggaaagatt tagaaaatga
     8461 tattcaagaa atgttgaatg gatcagttca aaataagttt gcagatcaat caggtgaaga
     8521 atttttgaga aaactattta ttgtaacagg taaaccacca attactgata agagtagtga
     8581 gaaagaaaaa atcgagtact ataagccttt tacttttaag ctaacaaact ttggaattaa
     8641 gacatctagt agtgggttgt atgaagcatt gaccgatttt gaagttcaat acaatggaaa
     8701 aaaagtgtat gataccacat taaccatcac actaaataat gataagaaag tgactggggg
     8761 tgctttttat gcaaaatcat gaaatcacta ctgctaaaaa ggcgatcgga atactttcca
     8821 taattgtgat cctttgttgt gtggtactat ttcaaaagaa aaatgcttat gataataatg
     8881 tcaaagaatt ggaagacctt aaaagtaaac aaatcgaagt agtcaagaat aaccagaaag
     8941 tgaaagctat gcaggaagct caatacaaag aattggggaa tgctgaaatc aaggaacaaa
     9001 gtaggaaatt ctttaattta ttttacaact ggaattcatg ggaaaaatat acgaagaata
     9061 tgaaggaaat acaaaaagaa tttcctcaga tagtaaagtc tagtcctgtt gatatttctg
     9121 gcacgatggt aggcactggt aatagtccaa tatctagcta tactgctgat tactatacaa
     9181 caaatcaaaa aggtaaaatg gttgaattga ttacacagac aagaaatact ccaacaacag
     9241 caacaacaac aatttggcgt ggagtaacaa gcataggaga aaatcaattg ttttacttgg
     9301 aggatttaga tagctatgta agagcggagt aaaataaaaa aagagctaac ggtaccaacg
     9361 ttagctcttt gtgctgacga tgataacaaa acctaccgaa aaaggattgt ttcatcacaa
     9421 acacaaacag aaaagaattg ataaaaaacc cgaacctcag aatttttatt aatcaattca
     9481 tttagattat aataaattga gctgaacatt acaatacgta tatgttgtaa aacgtaaaaa
     9541 aagtcaaaag taaatacttt cttaaaaagt caaataaaac tattaaagac aatatatatg
     9601 gtttatttga cataagaaaa tggtctagat gataattgta atatagaatt gtaggcttaa
     9661 ataaagcata aaataccttt tatgataagg tatagctctt aattttaagc agtttttaga
     9721 tataagagtg aaagtaaagt gggggagaat aataatggca gatcgtaaat tagaaaagtt
     9781 attagaagaa acgtggaatc caaaagaatt tagtgaattt tttatggaga attttgaaac
     9841 tgacttagca gtgattgtta aagatgctct tagagagcaa gggtatcctg aaactgcaaa
     9901 ctatataaac attaatttta ctttgtatac tgaaaataaa ggaacttggg atttttgggc
     9961 tactttagca aataaggagt taagtgataa atcagacaca ggaattcgta acttttttga
    10021 atcaaacaga gatgattata tgtatgctaa ccatcaagat aaattgaact ttagagtaga
    10081 gtttgatgaa acacctgaag aatttataga aagacaaccg cctaaagaaa atgtagcaaa
    10141 ggtattggaa gatcgttgga attcagatga aatagtttca acaattagcg aactaggcgg
    10201 acaatatgaa ccgctagtag aagcggttag agaagagcta agactgaata agtttcctga
    10261 tgttcaaaat attgatgttt ctcaaattga aataaacgtc aagatcacga ataaacttga
    10321 ttatggtagt tgggcagata tagcattaga aaaatacatc tactcaacgt taaaagagtt
    10381 tatcgaaaat agaatggata tcatgtatct acagcatcca cagtatttaa actttggtgt
    10441 tgaaatagct acacctcttg aagaatggaa aatggagcaa gggcttgact agcctttgct
    10501 ccattttttt attttacaaa tgaatacagt tcgtcgtttt taccaagaat gattgtttgc
    10561 ccaactttga gattgtcagg tgatccttca gcggtttgta aggagaacgt tccgttgaac
    10621 ttatcggata ccgttatagg tagctttaat tctgatcctt cctcatcttt gagaattgct
    10681 gtttttcgtt catcaaaata aacagtcttt attaaataat ttttcgtagt gatctcagca
    10741 gatttgtctt tttttgtagt agtaacagtt tctttagaat tagaggtatt ttctacgact
    10801 attccatctt tggcatttga gcttgtgttt atttgattga atattttcag cgacaagata
    10861 ccgctaagaa tagtcaatat agaaacaagt gtaattaata ctgataattt cctttttttg
    10921 ttcatttttt cttaacttcc tttttgtttt gattagttag atattcctta tctaacaagc
    10981 ctttttaggc tattaaatga agataaaccc caaaaaaata ttgcaattat gacagtgcaa
    11041 tggtactatt attatacaat aaattttgcg aaaggggtag gtctaaatcg caaacaaaaa
    11101 gaaattgaac ctagacaaat acaacttgta caccgcaagg gaagcaagtt tgattttggg
    11161 taaaggtaga aattatgtta caaacataat caactattat ccaaatcgtt tgcctaaagg
    11221 ttcgttcaag aaagtgggtg acaaaaccta tattataacg gaagaaggaa tagaagcatt
    11281 gcgatcacaa acagaaaata aaaacaaaaa gaaggaatga atatgaagaa aaattcgctt
    11341 ggtatggttt tatttgcatc agctgtactt gcggggttat cagtaccagt aacctcacat
    11401 gctgatgaat ggactgcaaa cacaccggat caaatccaaa ttacaacagg acaatcaagt
    11461 tatgcgttca aaaaaggaga tactatttgg tcaactgtag agaagcttaa aagcttaggt
    11521 tacaagacta ctgttgctga gtttgccgaa ttgaacaatg ttgatttggc aaaaggagaa
    11581 caacggacta tcccaattgg acgaactttc aacatcagta aagatacatt aacagttaag
    11641 gaagcagatg gcgaagtagt tagtcaaact gttcaaaaag ataaacctga tcctgttgaa
    11701 aatacggagc aagagaacaa aaaatccgag actgcaaaag aatcggaacc aacagcaaac
    11761 acttctgata agacagaaac aagtgcttca agtgttgatg gagcaagttc atctaataca
    11821 aataattcta caagtgagaa agaagcatca cagggaacaa gtgaaagtag cactacggaa
    11881 actgatactg gaacatcaac aaataactca caatcaacat caaatgatgc aaatgaatca
    11941 accagtacat cttctagtga tcaatcacaa acaggttcga gtgatgaaac tgacagttct
    12001 acttcaccaa gtaaacccga acaaccaact aatgttgtgc taggcgttcc atttattagt
    12061 caaggtaaca caatgctttg cgaaggaaca tctttgctag aagcgttaca ttataaaggt
    12121 gttgcaacaa atcaagattt aatgactttt gttaaatcaa tgccactatc tcctgataat
    12181 aatccaaata atggtttttc tggtgaatgg agacacaatg tggatggaac ttatcaaggt
    12241 atgaatccgg ctcctgtagt ttcatggggt gttgctaatg gcggaaatgt tgtagatatt
    12301 tctggttcat cggtacaagg attaaaagat gagattgtaa atggaaatcc tgtagtagcg
    12361 tgggtaactt atgcctttga acctgctcaa cataaatcaa tgttttgggg cgatgctatt
    12421 tggaatcgac atgtagtagc cgttgatgga tttaaagacg gtttttacca tgttgtcgat
    12481 cctgtgtttg gggcaagttg gattaatgca ggatcatttg aaacagcata taacgtatct
    12541 caattagcgg tttcggtacg ttaataaaag agattgttta tatactaagt agttaagtat
    12601 agtctttatt tgtccttgct taactactta gaaaacttgt tgctcatggt gggtagaact
    12661 aaaaggggtg atgctatgaa tactagagcg ttgaaacagc ttgctttcaa cgaaaaaagt
    12721 gattaatagg tgtggtgatt ttaacttagg aatgggcgcg aaggtcatta ccacaccgac
    12781 atatcgtggc tcattttctt cgcctaactg gtataaagaa ggagtaacga gagatgaagc
    12841 atgaaaaaac gataatttta aaatcaaaaa taatttattg ttttgcgact ttagtaatgg
    12901 tgttatctac gcttataatg cctttttcag caataagagc tgaagcagat gtcacaaaac
    12961 cgacaagtgc aaaatttaca gaaactggcg taaaaacaga cggttatatt agggttaata
    13021 tgccgaatca tccaaatgaa tggatgattt caagtcaatt taaagattct catggaaata
    13081 ttggatattg tatggattca gaattgccat ccccaacagg aagtggagcc ggaagcttga
    13141 agtacaaggg agctggcagt gatgagttct atcgtatgtt taaaggtggt tttccatcaa
    13201 aaacagcaaa ggaactgggt gcaggaaatg atacagaagc atggtatgca acacaattag
    13261 tttcatgggt tttagccgga aactttaaag tttcacagat tgtatggtca catccaaacc
    13321 ataccgccgc agaaacagct cgtgtaaaaa aagcatttga aaaaatttat gactatgcta
    13381 agaatggaaa agatacgccc aacactgagt tttctatcac agcttctaag acagctgacg
    13441 aaggaaaata tcacactttc acatataaaa cagcatcaaa taagactggt aatgcgaagc
    13501 tcacttttac atcagcaaaa ccagctggta tgaagattta tgatgcagat ggtaaagaaa
    13561 ttactaacaa cactgtgaaa ttaaattcaa gttttactat taaagtacct gtgactacac
    13621 caagtggtac tttgtcattt aaaggtactg ctaatgttag cacaaccaat ccttttactt
    13681 ttgatggacg aggcgtgtat caagatgccg tagttatgat cactacttca gaaacaaagg
    13741 actctaaatc tttgagtgct aaatggacaa gagctgttgg tcaggtaaca gttaagaaag
    13801 ttgatcaaga tggaaatgct ttaaaaggag cggagttcac tctaactgac aataacaatg
    13861 ctaaatctgt taagacaacc ggagatgatg ggttagctac gtttgatttg caacaaggct
    13921 taacatacag cttagaagaa acaaaagttc ctgaaggtta tcaaggttca tttaaaaagg
    13981 atggtattac tgttaatacc gatggacaaa aatttagtta cactgctacg aacacaatta
    14041 aaaaaggtaa agtaaaagtt aaaaaggttg accaagatgg aaaaccatta gctaatgctg
    14101 aatttacctt gacggatgat tcatcccaaa cacaagcaga aaaaacagat gaaaacggac
    14161 ttgcaagctt cgatattgta gcaaacaaga cctacagcct tgaagagacc ggagtaccaa
    14221 ctggttatac aggcgcattc aagcaagaag gaattaccgt taaagatgat ggacaaactt
    14281 ttgaatatac agctacaaac actttgaaaa aaggtgtagt aaaagttcat aaagtcgatc
    14341 aagatggaaa acctttggca aatgcagagt tcactttaac cgatgaaaaa ggtgcaacac
    14401 aagtagaaaa aacagatgaa aatggacttg caagcttcaa tattgtagca aacaagacgt
    14461 atagtctaga agaaaccgga gtaccagtag gttacacagg tgcatttaag caagagggta
    14521 tcagtgttaa agacgatggg caaacttttg aatatacagc tacaaataat ttgaaaaaag
    14581 gtgtagtaaa agttcataaa gtcgatcaag atggaaaacc tttagcagat gcagaattca
    14641 ccttaacgga tgaaaaaggt gtaaaagaag ttaaaaagac ggatgcaact ggtctggcta
    14701 cgttcaacat tattgcgaac aaaacttaca acttagaaga aacaaaagta ccaacaggtt
    14761 acacaggcgc attcaaacaa gaaggaatta ccgtcaaaga tgatggacaa gtctttgaat
    14821 atacagctaa aaacactttg aaaaaaggtg tgatcaaagt tcataaagtc gatgatcaag
    14881 ggaaagcatt agcaaacgca gaattcactt tgacggacga caaaggtgta aaagttgtac
    14941 aaaaaacgga cagaaatggc ttggcaacat ttaatattgt tgccaacaaa acgtacaaaa
    15001 tcgaagaaac acaaaaccct aatggttata cagggaaatg gtctaaagaa ggcatcaccg
    15061 ttgctgacga tggacaaacc tttgaatata cagtaattaa tcaccttgta cctgaaacag
    15121 taagaacagg cggaatcggt acatcagcct tccttcttgt atttctaatt gcaggattga
    15181 gtatggtgct actgtattat cgagaacagc acaaagcaaa ataaaaaagt gttaatggaa
    15241 aagaagtaaa tatgaaaaaa gaaggctgac gtatgaaatc aaaaaaaatt ttttcaaatt
    15301 taatgctatt tggtactttg ctaggagtgg gattgggcgc aagctcaatc tcttctagcc
    15361 ttggactagg ggggcaagta gcatatgcac aacaaaacta taattatcaa ggaactggaa
    15421 cgattcatat ccataaagta acaaatacta atggggatgg gaaccctgtc tcagatattg
    15481 ataacaaagg gaaagaaata gctttaccaa atggtgtaaa acctcttgaa ggcgttgagt
    15541 tctcttatgt gaaacttact aaagatgaag ctaaatcctt gggatggacg gatagtgata
    15601 ctacaaaagg tcaacatatt gatgatgcta aagcacgatt attactaaac aaaaaataca
    15661 gtgaagtaag tagaatgaag actgattcac aagggaatat agacatacct atacaagtaa
    15721 atacagacga tttaacagat aacttgtatt tgattgttga aacaggaaca gtcaaaggtg
    15781 tagttgaaga agcgtatcct atgattgtta acgtacctga actaaacgga tcagatgatc
    15841 aatactttaa ttatgatgta catgtctatc ctaaaaacta tttccaatta aactcagcag
    15901 agcttgataa aaaagacgaa gatggaaagg ctcttgccgg aactgttttt gaattgcgaa
    15961 aagatgatgg atctgatcag gttgttggaa cttataaaac agacagcaca ggtaaattaa
    16021 ctgtggatgg tttggaatta ggtgactatt atttcctaga aaccgatttg ggaacagatg
    16081 ctaatagaac aacctattta ctagatggta aaaaattcaa atttagcgtt aaacgtgggg
    16141 agactgctaa agtagttctt gatgttacca actacaaacg acctgtaatt actaaggtaa
    16201 ttgataaaga aaccgttgat actggcgaag atgttcaata tacattgaaa ccatcaattc
    16261 ctggtaatat tggtaattac gaaaaatatg ttgtcaaaga tgttctaggt gcagagttaa
    16321 cttatgattc atcagaagtg atcgaaggaa tgactttaga tactgattac agtatcgaac
    16381 gtgacggaca aacgacaaac tatgtcttta ctgaatcagg tatggataag cttcagaaac
    16441 aatttgatgc aggggatcgc ttctttacaa ttttgatgaa cgctcatact aatagtaaag
    16501 ctaaaatgga tacaccactt aagaatgatg tttcaacgat ctacaacaat ggatatgaac
    16561 ccgaagacga aacaccagtt gatcacgctt atacaatcat tggtgatcac caattcatta
    16621 aaacagacgg agatacaagc aaagcattga gtggagcaaa atttgtagtg aagaacaaaa
    16681 ttgatccgaa taaagttact tacctaaaac aagatccaac aacgaaagct gttacttgga
    16741 ttgcagataa atctaaagct actgaattcg tttccggatc agacggtaag ttccaaattg
    16801 aaggtttgca atatacctat gatgtagatt ttgataaaca aggtaatcca acaatcacag
    16861 ataaaaaaat caatgattat gctcttgaag aagttgttgc tccttcagga tatacaccaa
    16921 ctagaaacga tgttccattt gtggtatcga atgatgatgc ttctagcgaa gtaacagaca
    16981 tcaagaacct taaaacacct gaaacagttc gtacaggtgg aattggaaca gtagtatttc
    17041 tagtggttgc aggtgtggca ggaacagggc tatatgttgt ctacaaacga gaacaacaca
    17101 aagcttaatg aaataaaatt ccctagagtg tttttggctc tagggtttct ttttaaaaag
    17161 tgtgtgaaaa gtaggtatga gcatgaaaaa gaagaatatc aagttgatca tcttaaaaat
    17221 tgggatgttg ctatgtttag gagtaggtct atatcctgta attactcagg cttataccta
    17281 ctaccaaact caacaaacac taaactccta taaggaaaaa tatgatgaag cttctgaaaa
    17341 ggagaatgaa gaagtcttca agagatattc agaagttaat aggaaacgaa aagacacaga
    17401 acaaacctca gtcacgattc ctgaagataa taacaatatt ccgtcaaatg gaaatcttca
    17461 gaaggataaa ttaggtgaat tagtgggtga aattcttata ccaaagatta atgtggattt
    17521 gccaatttat gatggtgtaa acgatttcca actatcagca ggagcaggaa tattaaccgg
    17581 aactgattat ccaactggtg ggattggaaa ccattctgtt atatcagctc attcaggcat
    17641 tcctaataaa aaatatttta cagatttaga gttgctcaaa cttggtgata aattttttat
    17701 tgatatttca gggaaaaaac ttgcttatca agtagatcgg ataaaaacaa ttctaccaac
    17761 cgaatttgag gatttgcttc ctgtggcagg aaaagattat gtaacactta tgacatgtac
    17821 acctgttgga gataattctc ataggttact cgttagaggg gttagcatac cttaccaaaa
    17881 aagtattgtt gagaaagaaa agaagaaaga agatttaaag gtaaaggcgc agatgaactg
    17941 gtatcctatc gtagttgtag gggttttatt aataatagct gtgatagtca ttattaaaaa
    18001 aatagtagca aagagacgag gaatgaaaaa tgaagaataa aatactactt tttttgactc
    18061 ttatttgcac tttggtttta acaatttatc ctgcaaatca gctctatcat caattcaaaa
    18121 caaaagagaa tgtggcggaa atccaagaga aaattgagaa aaaacaaact ccttcaaaag
    18181 aggaagtggc aaaaaaagtc gaacaaataa aatcgaacag cggtaaccaa ggattagaca
    18241 atactcagaa aacagataaa ggagtagaca atactcagga aacagacggt ggatcatttg
    18301 atattcgtga agctgaagga aaggtcaatc catacacagg agatgttttt tcaaaaaatc
    18361 aaacgaaaga ttttgaacca tctacctatt caggagcggt tggttatgtc tatattccaa
    18421 aaataaatgt gctagagctt ttgtttctag gcgcttcaca ggagcattta tatagaggtg
    18481 tggcacaaat gagtgctact agtctacctt tatcaggtaa aggtcatcaa acagtaatag
    18541 caggtcatcg tggcggttat acgtcaccac aatttcttta tgttgatcaa ttagtagccg
    18601 gagaccacat ttatatagat tatcttggtg aaaaagcagt ttatacggtt ttccgaacag
    18661 acgttattag aaattacggt cagaattcaa cactgactga tattcctgat ttagatatgt
    18721 taacacttta tacttgtcat ccatatcctc agaactacga tcgtttatta gttagaagtc
    18781 taagagatga aaaagcaaaa tacatcacgc cacaagtaac agttggcaat accgcatacg
    18841 ctgatgccat tgatagtgaa tccgtttcag ataagccaga aactgttaca tcttctaatg
    18901 atttatttga ggatgttgat cgtgccaaca aggaattaga tggaaataat gatcttaata
    18961 ttccggaaca aggtagcgta gagatgcaag acagaacgtt tgctgaaaag gcaagttcaa
    19021 tatttacagg aattaccaat aaacatcaga aaatgctttt agtcatttgg actgtattag
    19081 gagcattagc aagtctaaag gttcttattc ttttaatcaa agagtttaga aaagcataat
    19141 gaagattata aaaattgata gagtacagta aaaagggatt gatactatta ttgatctctt
    19201 ttttattttg aatagagcta gattcacttt taaataaaat aaaaactgat cttaattcca
    19261 aagaaaaagt caagaaaaaa atacaacaaa tttttttatc agaatattta tcagaatatt
    19321 attagaaaag ataaactcaa aagcttaatt taatagggtt attggttgta tttagaaata
    19381 atgtatggaa aagctataaa gcaatagata agatgtagaa aatcttattt gtgaatgaaa
    19441 aacaagtcat cgtaaaatat taataggagg tgtagtaatg gtggaaatat caaaaacagc
    19501 tttagactca ttagctaaac tatttagtag caggtttgat ggtgcagaat ttgttgaata
    19561 tctaagccaa aacgaaagtg gaaaaactct gatcgaaaca ctgaaaaaag actatttgaa
    19621 tgaaaatgac tttccgacat ggacgaatat tgaagatgct acatgggatg tagtgtgtac
    19681 gatatattct ccttgggtaa cgattgctga ttttgtttta gataaaattg gaggggatac
    19741 ataccctgat gccaaatctc ttgctacaag tgactttaaa acgttctatg gttatctaat
    19801 gggtctaata ggcaatggaa tagatttgaa agttacgcca aaacaaacac ctgaagaaat
    19861 tgaaaaagaa aaaggagagg ttcaaatggc ttatgcagat gacagagaaa aagtaaaatt
    19921 attggaaggt aaattatctg aagaagaact tggaaaaatg gtgcaagaaa tcaatgaaga
    19981 cagcaactat tttcctgaat tgaaggtata tcaaaacgac gaagatttct ttaatgaaat
    20041 gtttagtaat agtccatggg aagcagtgag taaaacaaat ttaggagaat ggaactttca
    20101 agatgatcta gttgcattta gcaatgatgg gtatttacga tcatattcag aaagtgagta
    20161 tagagctgaa ttaaaaacgt atgaaacgga tattctgatg agctatttaa atctattaga
    20221 gagtggtcag ggagagttaa gagataaagt tgaagaacta ttaaaagaag agctataggg
    20281 attatttcaa cataaacaca agcagaaaac taccaaacaa aacgtaccat gcaaaaagcc
    20341 ggttaaaccg gctttttgct ctattatgag aggagatcaa accatgagtg caacaaccga
    20401 tatggcttta gaagcagtaa taaaagataa tacaggaaat gtcgaaaatg tagaagactt
    20461 tagcgatatt gcaatcaatc tttcagcatg gatttcagct gtaggagaag aaaatatcga
    20521 atttgagatc aagaatatgg atgacttaaa agcaaaattt ccttttatcg catcgaaact
    20581 aagtcaattt gccgaggaga aatcgtggaa tgaattagtt agtttttccg aaaaaattta
    20641 tgatattacg caagaagatg agtgtgtttc atgggaaatg aataatcaat acaagaaaat
    20701 tgatgctttc gtcaaatcac gtatagaagg aacagctttt gagtttgaag gtatagatac
    20761 cgcagataat tggttaaata aagaatcctt tattaaaagt atagcggatg atcttgaaaa
    20821 acaatggtct aaggaagact atgcagagta cctaaaaaca gaaagagata cagaggtgaa
    20881 agaaaaactc actgaggtat gtttggatga acatattgat cccaatatcg taaaacaaga
    20941 agactatgaa gtggttattg ataaagttcc tactgatttt gaggaagttg taaagtatat
    21001 agttgaagaa gcattatcgc aatactcttc agatgaggaa gtggacgaag aaactgttcg
    21061 taccagagtt tggcaactgg tttttgatga caaagattat aaatatttga gtgatcaaaa
    21121 ctcggttaat tggagtgtac gattattaat tgatcaaaat gatattgaat aaaatagagc
    21181 tgaaaagctc tatttttttt gataaaaaaa ctagctattt ttttaaaaat aatttggttc
    21241 aaaatttatt tttttaactt gataattttt tgccatcctt ttttaaattg gctatatatc
    21301 aaggtttata gtggggataa ataaaaatac atttgacaaa atttacaata tagtttatta
    21361 tatatttatc ttattatgat aacacaataa aaggaatgat ggtatgaaaa agaagaagtt
    21421 tagtcgatcg ttgttaggaa ttttagtttt agttgcggtt ggtcttagtg gcaagggtta
    21481 ctttcagaat aacagcactc aggaacatga ttttcagatc aaaagtagtg ttcaggtagg
    21541 taataaagca gacagtgaat caaaagaatt tttagggata cgttatgatc caaacaaata
    21601 tccaaataat atcgtaaaca ttaatgatgg gaaatataca ctgacaaaag aagaccatga
    21661 agcattatca gaaaaaggca gtcaaacctt ttgggtaaat tatgcagatt tagatcaact
    21721 tggaagagca ggagatgttg aagcgttgat cacctatgat gctataaatt ctcactcatc
    21781 taaaaatgtg gaacgtccat ctttcaaaag ttctgtccat attgcaggag aatacaagga
    21841 tggagtattt gatcaagaga gagatacttg ggtcggcaaa gattcaaaca atgaaatcac
    21901 tcagctagaa ggatataaag gttatctcta taacaaaagt cattcattag catggtcgct
    21961 aggaggagat atggaggtac acaatttaac acttggaacg agagcgcaaa atgttgggaa
    22021 aaatgatcag aatggaggga tggcttactc agaaacgatt gtacgtgatg caatctataa
    22081 aaataagaat gaaaaagtat tgtataaagt tgatccaatt tataaaggga atgaattggt
    22141 tcctcgtggt tctcatgtcg aagctttctc agttaacgat aatggaaaaa cggtaaacct
    22201 taatgtttat gtatttaaca atcaaaaagg aatcaacatc aactatcaaa atggtacttg
    22261 ggtaagagat tagaaattga gaaggtgaag aattggaaac aataagcatc aatggattag
    22321 ataaatcagt tgcaaatcga ataaaaaaag gaaatggcta ctatcttctg aagaagggta
    22381 aatattcagt tgctagagag ttagaaacaa tgagtatcgt gtatgtagct aagaatcatt
    22441 ttgacgtaga acaggctatt tttgatccag attctgaaat agggaaatgt gttgaattat
    22501 cagagaaaac tgttagtaca aaaggggcga tgatcattga gagagaaatg ttagacgaaa
    22561 tcagagtaat cattcctaaa gatacgcaga tgtgtgagga cagcataagt gacgatgaac
    22621 caaaatcaga aagaaaataa ggagatattc agatgagcga aaaatccatt gaattaaagg
    22681 aatataagcg aagcgatgga gaaaaatatt atcctgtagc cagtttttct aaatcagtat
    22741 atctggttgg acgtgcattg gtagttggtg caattggcat atatattttg cattgggtaa
    22801 caaaggttgt acaactgctt gtagatacct tagtaagtat tcttgtctcg ttaaatgatg
    22861 ttaacggaac agatgattta ggattaaaag aaatgtttaa agagttactc aatgcgtttt
    22921 ttcccaatta tttaagttat tcatataatg tacaaagctt ttttgcaaag ctacacttgg
    22981 tagacatctc tattttagta ttagaagcag gaacggtatt ctttgttgga tatttggtta
    23041 ctttgatgtt caggcatcac tatggagaac aaagaccatt ttttgatgat atggaaagta
    23101 gaaggttgaa aagagaagct ctagaagcta tggatgtgaa gtatgatcca aacaagatta
    23161 taggagatga aacgaacaac aaaaaaagaa aacgaaacaa aacgcaatta gaatccgatg
    23221 tgctatcaac gcttaaaaat atcaaaattt ctgttcatac aagacgtgat ctaagtgtca
    23281 atgaagatat tcgagaatat atcgtaaaaa tcccgcaacc aaaagggaag aaagttagag
    23341 aaacagtttt acgacaaatt caagatttag ggtcgatcct gacaagagca acaagcggac
    23401 gagccaaatt tggtgaaaaa gaagatgaag tttcaggcga ttatttcatt ttccgagcat
    23461 cagtaaatat tgaaagagaa cgtaaggaaa gagtaagtac caaaaacaaa gaaacggaaa
    23521 gagcaacatc ttcaatcgca gtttcaaatt cacaattttc ttttccaatc aatctctttg
    23581 ccgataattc caaaaatatc caaaaccaaa ccgaaaaagc tagaaaatat gccgaaactc
    23641 aaaagcaatc tttagaactt tatctatctt ctgctgacgt acctgcaagt ctaacagata
    23701 tgcacgttgg gaatacatct attgaatatt tgtttacttt atctcgtacc agaaaaattc
    23761 aactaagctc aatgaaagaa gaaattgaaa cttacttgca tatatcaggt gtaatcgtgc
    23821 ggatcaacgc agggcgtatt caaattactc taccattagg agaaaatgat cgtattccaa
    23881 ttgatgtacc atcaatgatc aatagcgtgt tttaaaagac atcacaaata gaaacagaaa
    23941 atacaaacta ccagttcaca aacagaaaag taccgagaaa agtgaggaat agaaatggct
    24001 atgaaattat tagagaaagt caaaaagaga gccgaaaaag ctgaatctat tttgctagat
    24061 aaagaaccta atataaagct taatggaaaa ttcagtgtca atatgttgaa cacaaaggct
    24121 aaagacccga cagatgctat ttttggaatt aagcctgatg gcacaattgc tcatttttgc
    24181 atcagcgaaa tgccacacat gttggttgca ggaacgacag gatcagggaa atcagtatta
    24241 ctgaatgaaa ttcttgttac agcaatgtgt cactcaacgc ctgatgaatt aaaaatagga
    24301 attgtagacc caaaaagggt tgaatttgga agatacaaaa aattgccgtt catgttggct
    24361 gatccaatta cagatatgga tgaagcttat gatttttttg aatatcttgt gatcttgatg
    24421 catgaacgtt acaaactgat ggaaaaagca gggttacaaa acatcacgct atataacgaa
    24481 tatgccgaaa aaaatggatt agatagattt ccctatgtga tcttattagt tgatgaatat
    24541 tcacagttgg ttggaacaca taaagaagta gaaggtttga ttgttcaatt aggacaaatg
    24601 gcaagggcag caggtattca tgttatctta gctacacaat ctcctcgatc aacagttgtc
    24661 actggtatta tcaaagccaa ttttccgtca cgtgtttgcc ttatggtagc aagtgattta
    24721 gaaagtagga tcgtattaga tgaaggcggt ggagaaagcc taagtccaaa gggagatatg
    24781 attattaagc tcgttaatgg aagtatggtt agagcgcagg gagcttacat cagtaacaaa
    24841 gaaattgaaa caattttcaa tcaccttaga aatactatgc cagaaccaga atatgttgat
    24901 taccgagcaa tcgtagctga atctcgtggt gagggtggag aagacgagga ttttggtgga
    24961 attggtaaag ctcctgtaag aaaatctgct aaaagaaatt tgaacacacc tttagcaaat
    25021 tcatcatcta aagagccatc aattgaaaag aagagtacgt ttgctctaaa acttgaaaaa
    25081 aacaaagaag aaaaagaaaa acaaggagct aaaacactag aaaaacttca agccgaaaaa
    25141 ttagaaaaag ttttaaaagc attagataaa gctgattctg aaccgcaaac ctcaaacaac
    25201 acgaataatg aacagccgat ttcatctaaa actaaaccga aaactactga tccgaaagtt
    25261 tcagtaaacg tgaccatcac aaccgataag tctgagaaga aacaagtaaa cggaacgact
    25321 tcacctatca tgcaaaaaat gttgaaagcc aaaaaacagg tgcataaatg atcattgtca
    25381 gttctttttt gaggtggctt acgccatata aatatacaga tgaagtagtt gtgaaacgaa
    25441 cgaagaaaag agataaaaaa gcggtactaa ctcctaaaca gatgcttgat catggcattt
    25501 taggggtgaa ggttttagaa gtgaataaac cgtttgaatc aaatagtgca agagaaaagt
    25561 tgcttggagc tgaagccgat gtcgcatatt tttaccatga caaaagcaag catcaaatag
    25621 ctattaaatt caatccaaaa tcggcatggc ggtatcaagc aagagatgac ttgaaacgta
    25681 ggaaacttag accaatgctc tatccagaag gaaaagaagc atttgataga acccacatcg
    25741 ttcccattgg ttttcatggt acagaatcag ataaccgcct attagtaggt tggaacagca
    25801 atcaaaatag agttcagatc aataaatttg agaagaaagt aaggaaattc aacgatcgaa
    25861 aaacgatcct atggtttgca gatatttgta aacagccgga tggaacagca aagtgggaag
    25921 cggtgatatt tgacgaaaat ggtaaaaaag taatgtctga aacatggcat gataaagcta
    25981 aatttgtttg gcagtagcag tagaggtgaa aaagattgct agaacttttt gaagcaaata
    26041 gaacaggctt taatcaaaag ttagaagtgg gagaaactat agaatataaa gataaaaact
    26101 atattattat cggaatctat aacacgagaa ttaacagaat aggtgatcca cgtataacca
    26161 gtgacttggt ttgtcaatct gttaactatt cacctgatct gacaagcagg tataagaaat
    26221 acgtgttatt agaatataga cacaagatta ctgatgaaat tggtgtaaac aacacacgaa
    26281 acatatttaa gatcggaaca gtgattcctt atagtaacaa cgaagaaaaa atattttatc
    26341 agatttacgg aatagaaaag tttgaatatg aacatgtcga tctgctagtg acgtaccaaa
    26401 tgcgtttaat agaaccttgg tcacaggcag aaattgataa agcagtaaaa ttgaaccgat
    26461 tatcaaaatt taacgtatta ggaaatgcct tttaaaaatc gcaatacaca aacagaaaaa
    26521 taccaaaaaa ttagcaatga acgtaggtaa gaacatgaca ataaataata ataaccctaa
    26581 aaaatataat gctcttgtcc aatgctatat cgaaaacaaa attacaatgc aagaagtcgc
    26641 tgatgaatta ggcaaatcaa agagcctagt atcacacgat tttaagcaca atgtttttcc
    26701 gaacccgatt gagctgagga aaaaatttca aaagagagtt tatcaagaaa taggtaagtg
    26761 gattgatgaa gggaatgcaa ttgacccttt aattgaaaaa tatccttttt taaaaagcaa
    26821 aaataaaatt caaaggttaa ttcgtcaagg cgatattcaa gctaaagaac ctgttttgac
    26881 aaccaatgat ttggctaaaa taaatcttca taaacaaatt attgaagact ttgaaaaaaa
    26941 tctttcaaca actgaaattt taaaaaaata caatattccg agaggaaagc taacatcgac
    27001 tctttttaga gaatatggag aatcggcagt tactaaagca aaggaagtag cgaatgagag
    27061 aaaaaaacaa aaatagtagt cgatacctag tagcgactgt agtttttgtt tgtgtattga
    27121 ttttcctgtt tgattttttg cagattggaa aaagcataat tggaaataca ttgagtgcaa
    27181 aggaaatggt tgctttaggt ggtttgtatg aaggacactt gttcccgaat atattcattt
    27241 ctatcgtttc tcatattaac ttgtaccatt taatttctaa tttattgttc ttagtagttc
    27301 ttgaagaagc actgaatgat cagtatgagt ggttaacatt attgatcgtt ttaatcatat
    27361 caggatttct aggaagctta gttccttttc tgctacacag caacatcgta agtatggggc
    27421 ttagtggagg tatttttgga tggattgctt tatttgcgat tgcatacatc cgttttgata
    27481 gcaagaaaca tttattacta agtgtttttg tattattgat aatcggcatt ttactggtat
    27541 ctacttttga atcaggcgag acaaacgtct tgtcacatgt aatcggattt gtctgtggga
    27601 tgatcttggg atttattcta aagaacgttt cattgatcaa acaaaagaat taaaagggag
    27661 tgctaaaaat gccaaaaaaa aaagaaaaga aaattccagt gtttttgtct gtctcagaaa
    27721 tgttatcact tcaaatactg ttaagaaaaa agattgaaac aatagacgaa gaagttagaa
    27781 ataaaagggc tatgtacgaa caacgtgaag cgctaagaga acgaatccac tattttgatg
    27841 atatacacac taaaatctat gaagcacgta caaatcacga agacgaaagc aaattaggat
    27901 tagctcaaca acgaatattt gaatggctga atacgaatac tgagcaagaa ccgttaagag
    27961 caattagtaa tctttttgaa tttggaacga agcattggtt taacgctgta gaaaaggatg
    28021 ctgacttaca agaagcgttc gatacactaa gcgaggatag caaatccatg cgagacttat
    28081 tgatcactta tctaaatgag catgaatttg aacagacgaa agttaaaaag aaaaataaaa
    28141 aatagaaagt tgtgatgtat catgctgttt accttattag gttatttatg tttagttctt
    28201 gctttttttg gagcaattgc tatatttgtc ggtcagtttc aagaaaataa tccgataatg
    28261 cgtaacatag gcattggaat tgttatcata tccttgattg tatttggtgc cacaaagatt
    28321 tttgggagta atgatcagca gtttggtatt tctggagttg ataatagtta tgctccagat
    28381 tcattgggaa gagtagtgat agatggaacg tttgagaatg taacgagcta caaaaatgtt
    28441 tcattgacag tgaaagaaga tgacaagaaa gcatcagatg acgttctcgc tacgatcaag
    28501 ccgtctcaat cacagtttga agtgttttat acagtcaaag agaataaccc tgtacgcaag
    28561 ctaacattag tttttaacgt tgacggagaa gaatactata aagatgtaaa aatcaataaa
    28621 gcatcaacga aaaagattgt cgaatcagcg aaaaaagaag tagctacaga agaaagtaca
    28681 actgaatcaa gttctactgt cgaagttgaa ctaccagata aaattgattt tgatcctgaa
    28741 aaagtcaaat cgtttgaatc tgtttctggt tctatggcag atcggtttaa cactgaagtt
    28801 ttcaaagcta tcaaaactgt taaattggat actgaaaagc aaaggattaa tgttacctta
    28861 ttcaatgcag ttgaatctat ggatcaggat aaaaaagtta cggttgcaag agaactaggg
    28921 aaaagagtaa ttggattgta tcgaggtacg gcaaaaccag attcagacgg ttcagatttg
    28981 ccagttcacg tagtttatga agacggtaaa gtttttggag actctacagc aaatgaagca
    29041 ctaacgatta aattagctaa atagccggaa aattataata aacaagtggt gtcacaccac
    29101 catcgcatag gtgtgacacc ttggagatga ttactgatgg tagtaaataa agaaaaagta
    29161 agaaagtatg ttactttaaa aatagcttct gttgaatatt tagaaaagcg agctaaagaa
    29221 gaagaaaaaa caagaggtaa gaaggtaaca gtttcagagt tgttagaaga attaattgag
    29281 agtgaccaaa caataagacg tgcatttacc aataggtctg ttaaaagtta gggtgatact
    29341 atctttaatt tcaaccaaat ttctaatata tgatgaatag tttccttgta caaaatatct
    29401 aattaagaga taaaagttag gaggattcat tcaaaatgat tatccaaaag tttgactgga
    29461 aaatgaaatt aggaattagt cttgtaatat tgggatttat tatttttttg gggataaaag
    29521 cacaaaaaaa tcaatctact tttgaaacta tgtcttctca aattattgag gaatgttcca
    29581 aaatttatta ttgtgagaac aaaactgaag aatctaatgg cttttattat atcgatcaac
    29641 cacatgatgt tgttataaaa atggagtcac atgaagtaaa cgaatggatt caaagaagta
    29701 ctaatgtatc aaaaaagtta gaaagatatt ctcaaacgtt tttaagtaaa gtcatttttt
    29761 caaattgcaa aaatgaagaa acgtctcaaa gagtagctag ttctttagaa aatttaaaat
    29821 tttctgtttc aaaaaaagag aaatttgtag atttacgaaa ataaactatc gaaagtagta
    29881 tgattatgat cttaaaatat catcttaaga gaagaattac gattgtttat aggatttaca
    29941 aaatgaataa gtttgaagag tgatttggtc gcagactaga tcactctttt tgtgtaaaaa
    30001 aactttacac ttatttttga gtgtgttaag attttttata tagagtgacg gtttcttgtc
    30061 agagtggatg ataaccatca atattggagg aataataagt ggaaaacaat aatgatatta
    30121 gatattttag cattggggaa agagttacaa cagtaagtga attatcaaag gattatagag
    30181 ataaagaagg aacgattatt tctcttaaaa agaatcgaag aggtgtttgg caatatgttg
    30241 ttgatttagg ggatggcgtt acagttgagt gtaaagatag tcaactgatc agaaatgatg
    30301 gcagtcattc cattgaaaaa gcaattcttg tattcccaaa agtatcaagc aagattatga
    30361 atgactggtt gcttggaaaa tttggtgagt acaataaaaa agaaatcgca gaagtgatcg
    30421 gcaaatctta tccaacagta ttagggtatc taaaaaagat aacgaacaaa gaagcgaaag
    30481 ttgaggatgt tttaacagta agagaacttc agtcattaat cgaatatcgg aataaacaaa
    30541 taacaaatcc tgagtacctt aaaaaagaag atggtctatt gaaacaattg gaacaggtaa
    30601 ataaaatccg gaaaatgcaa aaggtagctc ctttaagcct agataacttt aaaaaaatct
    30661 atttgaaaga gatcgaaaaa gactaatgtg gagtgtcact ttaccgtttc aacctgtatc
    30721 tgcaccaaga ccaagtgcaa gaaggaatgt tgctgatgca actaatgacg tagcagagaa
    30781 aaggatttca acctattatg ataaaaagta tctcgattat ttgaaaaaaa taaaaagctt
    30841 tatcgaagat caaggtttgt tagatgatga attttactcg atcgtaaatg atccgatggg
    30901 tgcaattatg gaagtggact tttactatca gataccaaaa agctataaaa aagtctataa
    30961 cattatgaaa acgacagcgc cagatttaga taatttagta aaaagtgcta tggatggtat
    31021 tttcaacatc tcagctatac gagatagcca tatcacaggg ttaattgctt ttaaatacaa
    31081 tgtggcaaac gaaggaaaaa cagttgtgag gatcaagcga tattcagaat ttgagtggga
    31141 tacttctgaa ggattgaacg gagatatttg ggaagccaca tttgatttca aaccagtagc
    31201 aacgccaaga ccaaagtcta aatttagagg aaatgggatt atcacttact atccaaaaga
    31261 gtataacgac tatttggaaa atatcaagaa tacgcttaaa gagaaagatt tggtaaatga
    31321 tcaactgaaa aaggtaatga atgctcctat gggggttata gctcagatag attattttta
    31381 ccaagtgaga aaagataaga aaaagcttga ttcactgatg cgtacttcac agccggatat
    31441 tgataattta gtcaaaggaa cattggacgg aatttttaac aaggaaatag gcatcaaaga
    31501 tagcagggtt gtagggttaa ttgcttttaa atacaatact tttgaaaagt cgaaaacaaa
    31561 cgtgagacta caggagatgg gctgatgaat aataatgaaa aaattcttca tgtacttgat
    31621 agctttgaaa taattcaaga agaactaaaa aaatatcggg atgttttgga acaaagatat
    31681 gattttgtca atcagcaaaa gagtaatcac atggatttca ttctcaatat gaatgacttg
    31741 aagaagaaat tagttgaacg aaaagaacaa gaaaagttga tcaaagctta ctttgaactc
    31801 ggtgaaaaag aagttaaaaa tgcaatggaa ctgaatgaag agcgcagggt tttagatcag
    31861 ctgttagaac aattattggt gatgtttcaa aaaggacgaa tagatgagga tttaattgaa
    31921 gaaggattga gaaaatatcc ttcaaactca ggtatcggaa tagtgctgaa agcgattgat
    31981 gaagaagaaa ttgaagcttt cataccgcca gaggattttg aatcggcaat ggaatatata
    32041 aaatattata gccaagggat cactgctttt agagagtttg atcctgaaga tgttattcat
    32101 gacttgaaca acctaaaaga atggtgtgaa agttatggag tcgatgattc cggattggac
    32161 tacttgatca gtattatgga aatcgaagaa gagatgccgg ataagcctga tccaacagat
    32221 attttagaat tgatccatga agctagaaat ccaattgcct atatttctag aggatatact
    32281 gtattggaat actataagcc ttatatatca gcgatgaacc atttaagacg tgtattaagg
    32341 gaaaaacgtg aataccgctc agtgttgaat gcaacgaata gattagaaaa agctgtttca
    32401 gagctagatg cttattatcg tgaacattac ctgcaagcag gtggtatgcc aagaaatacg
    32461 aaagcaaata tcagtaggta tataaaaaaa gctgagtagg cggagttagc ccataaaatg
    32521 gcaaaaggta acctgaaagg ggcattttga atgaaaaggg atgtttttga attgtacgta
    32581 ttagaacgtc tagaagacgg catgatggca caagagataa ttgatgaaat tgatgatatg
    32641 atcagcagat ttggtcaatt ggagttgaat gatggaaaca aaaattcggt agtgctaaaa
    32701 caattttggt tgaacaattt ttcgtataag gattttatca aagaaaaggc aaatacattg
    32761 tactgactaa attcacgagg agcagtgatg agagcttatt gctaagagca gttaggctct
    32821 tttttgtttg tgtaaaatta tttgttttat aatacacatt tatacacaaa aaatattgac
    32881 agatagtaca caaatgtggt aggatatatt tgtaagcaag ttagattaac aagttaaagg
    32941 aagagcagtt atgaaaaaag aagaactaat agatatattt caaattgttg aacgagcaaa
    33001 taatatggga attatgtttt ttgatcgtat ttctttaaa
//
LOCUS       DACGMI010000035        32112 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.036, whole genome shotgun sequence.
ACCESSION   DACGMI010000035 DACGMI010000000
VERSION     DACGMI010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.036"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(29..727)
                     /locus_tag="IXT46_001731"
     CDS             complement(29..727)
                     /locus_tag="IXT46_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAQ4947645.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(720..2072)
                     /locus_tag="IXT46_001732"
     CDS             complement(720..2072)
                     /locus_tag="IXT46_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAQ4947646.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2295..3695)
                     /locus_tag="IXT46_001733"
     CDS             complement(2295..3695)
                     /locus_tag="IXT46_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAQ4947647.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3856..4593
                     /locus_tag="IXT46_001734"
     CDS             3856..4593
                     /locus_tag="IXT46_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAQ4947648.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4718..5197
                     /locus_tag="IXT46_001735"
     CDS             4718..5197
                     /locus_tag="IXT46_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAQ4947649.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5194..5961
                     /locus_tag="IXT46_001736"
     CDS             5194..5961
                     /locus_tag="IXT46_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947650.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6191..6760
                     /gene="lepB"
                     /locus_tag="IXT46_001737"
     CDS             6191..6760
                     /gene="lepB"
                     /locus_tag="IXT46_001737"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4947651.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6864..7466)
                     /locus_tag="IXT46_001738"
     CDS             complement(6864..7466)
                     /locus_tag="IXT46_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4947652.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7572..8041
                     /locus_tag="IXT46_001739"
                     /pseudo
     CDS             7572..8041
                     /locus_tag="IXT46_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8147..8731
                     /locus_tag="IXT46_001740"
     CDS             8147..8731
                     /locus_tag="IXT46_001740"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAQ4947653.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8734..9807
                     /gene="prfA"
                     /locus_tag="IXT46_001741"
     CDS             8734..9807
                     /gene="prfA"
                     /locus_tag="IXT46_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAQ4947654.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9800..10639
                     /gene="prmC"
                     /locus_tag="IXT46_001742"
     CDS             9800..10639
                     /gene="prmC"
                     /locus_tag="IXT46_001742"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAQ4947655.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10632..10811
                     /locus_tag="IXT46_001743"
     CDS             10632..10811
                     /locus_tag="IXT46_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947656.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10833..11858
                     /locus_tag="IXT46_001744"
     CDS             10833..11858
                     /locus_tag="IXT46_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAQ4947657.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12033..13277
                     /locus_tag="IXT46_001745"
     CDS             12033..13277
                     /locus_tag="IXT46_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAQ4947658.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13430..14377
                     /locus_tag="IXT46_001746"
     CDS             13430..14377
                     /locus_tag="IXT46_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4947659.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14511..15140
                     /gene="upp"
                     /locus_tag="IXT46_001747"
     CDS             14511..15140
                     /gene="upp"
                     /locus_tag="IXT46_001747"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAQ4947660.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15279..15521)
                     /locus_tag="IXT46_001748"
     CDS             complement(15279..15521)
                     /locus_tag="IXT46_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947661.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15642..15714
                     /locus_tag="IXT46_001749"
     tRNA            15642..15714
                     /locus_tag="IXT46_001749"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15675..15677,aa:Thr,seq:cgt)
     gene            complement(15833..16471)
                     /locus_tag="IXT46_001750"
     CDS             complement(15833..16471)
                     /locus_tag="IXT46_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4947662.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16594..17226)
                     /locus_tag="IXT46_001751"
     CDS             complement(16594..17226)
                     /locus_tag="IXT46_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAQ4947663.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17577..17876
                     /locus_tag="IXT46_001752"
     CDS             17577..17876
                     /locus_tag="IXT46_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAQ4947664.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            18371..20536
                     /gene="acm"
                     /locus_tag="IXT46_001753"
     CDS             18371..20536
                     /gene="acm"
                     /locus_tag="IXT46_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAQ4947665.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPGATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(20808..21293)
                     /locus_tag="IXT46_001754"
     CDS             complement(20808..21293)
                     /locus_tag="IXT46_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAQ4947666.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            21773..22414
                     /locus_tag="IXT46_001755"
     CDS             21773..22414
                     /locus_tag="IXT46_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4947667.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            22433..23068
                     /locus_tag="IXT46_001756"
     CDS             22433..23068
                     /locus_tag="IXT46_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947668.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            23086..23901
                     /locus_tag="IXT46_001757"
     CDS             23086..23901
                     /locus_tag="IXT46_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4947669.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            24220..25656
                     /locus_tag="IXT46_001758"
     CDS             24220..25656
                     /locus_tag="IXT46_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4947670.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            25845..28292
                     /locus_tag="IXT46_001759"
     CDS             25845..28292
                     /locus_tag="IXT46_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAQ4947671.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            28522..29589
                     /gene="rlmN"
                     /locus_tag="IXT46_001760"
     CDS             28522..29589
                     /gene="rlmN"
                     /locus_tag="IXT46_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAQ4947672.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(29782..30885)
                     /locus_tag="IXT46_001761"
     CDS             complement(29782..30885)
                     /locus_tag="IXT46_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4947673.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            31438..31986
                     /gene="aac(6')"
                     /locus_tag="IXT46_001762"
     CDS             31438..31986
                     /gene="aac(6')"
                     /locus_tag="IXT46_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAQ4947674.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT        11021 a         5470 c         6526 g         9095 t
ORIGIN      
        1 ttttgtcaca ttcccctttt tcgaataact aggctgtttg tccttcaaga tagggcagat
       61 ccaattcttt accgtaacgt tgttctaaag ctaggcggat caaacgagct gccaggttct
      121 catttcttgc aaggataggt ccatggaaat aagaaccgaa gacatttcgg taaatgacac
      181 cttcagattg gtcttcacca ttatttcctt gaccttgtac cactttcccc aaaggtcgtt
      241 caccttcacc taagaaagtc cgaccattgt ggttttcaaa tccataataa gtttcattga
      301 attcttcgtt atggataacg atatcaccga taaaccggtt attttcctga cttaacgtgt
      361 agtgatccag tgcactgatt ccttggatct tttctccatt agctcccatg tagtagtgac
      421 ctagcaattg gtagccacca caaatggcta acatgacgcc atcattttcg atatagttga
      481 tcaaagaatc tttctttttc tggatgtctt ttgaaatgat taattgctca aagtcttgac
      541 caccgccaaa gaaaaccaag tcatatttat cagcatcaaa aggttcatgt atactaacga
      601 tctccgtatg gcaagaaacc cccatttttt ctgctatata tttcaacatc aaaaggtttc
      661 cgttatcacc atatgtgttc atcaaatttc cataaaggtg ggcgatattg agttcataat
      721 tagccacggt tcattcctcc tttgataaat ccttgagcag ctagttcttt acgaagctgc
      781 aatacagcag tgtaagtagc taaaatatag acatgctcag ttggcaattc tttgattttt
      841 tcgattactt ctggtaattc ttttgtttct gtcaatttat tttctggaat cccggcaact
      901 tttagacgta aagtcatatc tgtatgacgg tctcctccag aaataacagc tgggatatcc
      961 atatcggcaa agttttcaaa attaccatcc caaatccagc tgacatcgat tccgtctgcg
     1021 taattggcat ttaataaagc cactaaagaa aatggataag gagctagacc aatcatatcg
     1081 attacttgat tgatacctac aggatttttg acaagtacta atgtacattt tttcccattg
     1141 atattgatga cttcttgtcg gccgaatact ttctcgtcat atcctaaacc ttgtttgatt
     1201 ttatcaggat cgacattgaa gtactctgcc actgcagtag ctgctaaagc attgtagaca
     1261 ttatacatac cgccaacttc gattccgtat tcatgaccat cgatcacgaa atctgctgac
     1321 acattgtcca tccgtaccat atcagttaat cgataatcca attcaggacg tttgaagtca
     1381 caatttggac agtaatattt ccctaagttt gcataagtga tcattttata atgcaagatg
     1441 tgatgacaat ttggacataa gacaccgtct gtattgtaat gagccatttg ttcacgatct
     1501 tcttcatggt caaagccata atattttcta ggattgactg tttcgataga attgaagatt
     1561 ggtgaatcac cgttactgat aatcgttgca tttggtgact ttgcggcacc gtctacaatc
     1621 attttatagg tcgtatagat ttctccatac cgatccattt gatcacggaa aatatttgta
     1681 aataagaaca gttctggttt catatattct gtgactttgc tcaaacttgc ttcatctatt
     1741 tctaggacag caaacttttt ctgtcctttt tttggttttg cctgcaagaa agtcgataca
     1801 attccctgta ccatattcgc accagtaggg ttggttagaa cttcatcgaa ttgctggcgc
     1861 aaaatattga ctgttaaagc ggtagtcaat gttttaccgt ttgttccggt gacaacgacg
     1921 acttggtagt cttttgccaa actatctagt atatgtggat cgactttcag cgctagttta
     1981 cctggtaaac ttgatccgcc tttaaaaaaa gtttttaatg cccattgcga cgtttttcca
     2041 actgcaatcg caaaatgact gcgtattccc attatgtaac ctccaaaaac gatttgctga
     2101 cgaataaatt caactaatca taccatatgt tgaaaaaaag gttaaattgc ttttcttatt
     2161 cttaagaaaa ggttacggct gaaagtgcat gaaatcggac aaaatcgcat gatttaacaa
     2221 aaaaacagct tgaaacaaaa tgattgtttc aagctgctgt gattttatta ttccctctta
     2281 cctatattcc cattttaacc gataataatt ttctcgcttg gatattcata gcctagatct
     2341 cgtgtttctt ttggcacgaa taacatcaat gtatatagca ttccgatccg cccaataaac
     2401 atcagtgtag caatcgtgat tttgcccaca acagacaagt ctccggtaat ccctaaagat
     2461 aaaccagttg ttccaaacgc agaagttact tcgatgatga tcgagatcag cgtttgttct
     2521 tctgtagcag ataaaaaaac gatacaaaag aaacacatac caagagaaag cataaagaca
     2581 acgactgatt ttcgcacatc atcttgatcg attctccgtc caaaaatatt gatgttatct
     2641 tcacttttga ggaaggaata tagatacaaa ccgatgattg ctacagtagt tgttcgaatc
     2701 ccgccgccta cagaactagg actgcatccg ataaacatca gtaaagaaaa aatgatcagt
     2761 gttgtgattt gaaaatcacc caaatcgtga atctgcagac cagcattacg agtcgtaatc
     2821 gaataaaaca tcgaattgat ccatttgaca ctcatattgg aatcttggaa taaatggtcc
     2881 ttttccaata gataaatcaa gacagttccc gaaacaaaca agataacaaa agctaacaca
     2941 gctaatttgg taaacaagga aaaacgaaac ggaagcttcg cattggaacg tttgtataat
     3001 agccattccc ggcactccat caatacagga aaaccaattc ctccgacaaa aatcaaaaac
     3061 atgatcagga tcaagaaaaa atagtcatgt gcaaagggct tgatggaatc cccagtgacg
     3121 tcaaacccag agttcgtgac agccgatatc gcctgataaa aaccgtaaaa aacggcatca
     3181 cgccaacgat caaaatagcc tctgtaataa aaataaatag aaaagaatgt cccaaaaagt
     3241 aattgaaacc agattaaaat agcaaaagtg atccgaatca gtcggacgat accagacaaa
     3301 cgcggttgat tcatatccgt catgatcagc tgtcgctgtt tcagtgtgat ccgtcgttta
     3361 gaaaaaatga caaaagcagt agaaatcatc atgatcccca aaccaccaac ttgaaataat
     3421 atttccagca gtataatacc gttatcattg aacacagaat tgatatcaaa agtcgatagt
     3481 ccagtcacac tcactgtact gattgccatg aacagcatgt ccacaaaaga aacatggcta
     3541 tctggttcgc gaaaaatcgg catataaaat agaacgagtg ataagaccgt catcaatata
     3601 taataaaaaa cgatgatttg gatcgatgag aaatgattgg cagcaaactt ctgtcctcgc
     3661 cgctgcagcc ttcgaaagaa taaatcaaca tgcacagtac tatcctcctg acaatagtcg
     3721 tttctaccag tatacaaggg gaattaggaa tactcaaaga aattatcaaa cagataacaa
     3781 tacagctttc gattaaaata gaaatggctt ataataaggc aaatcctaga aaaaagaagg
     3841 aggaggaata acaaattgat taatgctcaa caaatcgtag aaaaaatgaa aaatcaaaaa
     3901 ataaattatg atacagttct gaaaaaaatg atcatgcaat gggagaaaga agaagtaaag
     3961 cctaagatat taatacatac atgctgtgct ccttgcagta cgcacacatt ggaattcatg
     4021 tctcaatatg cagagatcac gttatttttt tcaaattcga atattcatcc taaaagtgag
     4081 tatttgcgaa gattacatga acaaaaacga tttgtagacc aatttaatga gaaaactgac
     4141 catcatgttg cgctaatcgt tgatgaatac cgtccaaatg aattcaccaa aatggtttta
     4201 acaaaccatc ttgaaaacga aaaagaaggt ggtgctcgct gcagtgcatg cttcaatatg
     4261 cgattagatc ttgttgcgca aaaagcgcaa gaactaggat acgattactt tggaagtgcc
     4321 ctgaccatct cgccaaagaa aaatgcagct ttgatcaatc agatcggaat ggatatccaa
     4381 aagatttacg ggacacaata cttgccaagt gatttcaaga aaaacaaagg ctatgaacgc
     4441 tctttgcaaa tgtgcaaaga gtatgatatt tatcgccaat gttattgtgg ttgcgtgttc
     4501 gctgccaagc agcaaggatg cgatctgaaa gaaatcaatc gggaagcaaa agcttactta
     4561 aaaacatcaa ccgtagtttt tgaggaaaat taaagaaatc tttcggaaaa acgtaagaaa
     4621 aaaataaaga atttatggta gaaataaggt agactgtata atttgtccgt agtaaagtaa
     4681 ggaaacaaga ataaatttca atgaaggaag agataagatg cgaaaagtag cacctatttt
     4741 gaagccaatc gctgtattaa caatctcgac gattgtcgcg actactacag gtattgtgaa
     4801 tagttccagc taccgtgcac caagttcaag ttctagtact gtagaagaaa caacaccaac
     4861 tacttcagtc tcgacatctg aaccaacaac aacggaaagt ttgaatgaaa ccactacgac
     4921 aagtacatgg gacgatacaa caactagttc gtcgtatgat gagacatata caactgacag
     4981 ctcaagcgaa acaagtaata cggtaccaga tggcactcca tcggattcaa ccaatccaag
     5041 tacaagtccg gatacaagtg ctagctccga aacgatacca agcagtacga ctgtagatga
     5101 taacacgcaa aatgatgatg cagcacgtac agcacagcaa aaccaagatt caggaaatac
     5161 ccaaacgtat aaccagcaag caggtgattc tcaatgacat ttttactaga ccttatcaac
     5221 ggggtgcata aattccttgg ctatttagac atcagtccta aatatcttaa ccgtggatat
     5281 acgattttaa gtgtgattcc cacgctttat ttattgagaa ttgtttatgg actttggcaa
     5341 aaccaaaact atcttcaatt tttcttatat ggacttgcat ttctagtgct tgtttatttt
     5401 actgttttaa atgtatttta ttacttttta gataaaaaca cgaaagccga tgtcactcag
     5461 ctttttgtga agtatttacc tgatgaagcg ttcaacatcc agacagaaga atcgatagat
     5521 aatggaaatt cgatcgataa agtgaataca caagaggtca tggtttctta tgacgaagat
     5581 tatcaattga aattagccga gaatatgcgg tatttgattg gaaatggtga gatcaaaaca
     5641 aatgaactcg gtcgcatgga tggatttctg gtcgatagaa atacattgta tccttattac
     5701 tatgtcaaga aaacaggaga gaaagagtat gttctaaata ttggacgaag ctactcggac
     5761 atggaaaaag tagggaccat tcgacttgac tcaacagaag acacattgga acctgtcgga
     5821 ttgttcatcg tcggcggtga ttttgtcaaa gacgggttac gctatcatga gccttatcgt
     5881 ctgaaattga ttgcaaaaaa ggcacagtcg caggaagaac cagtggttta tagtcgtagc
     5941 caaagaagaa gacattcata atgtgatgaa acgccgtgta tcagtggttg cgataaaaac
     6001 gtttattcgg aataaggggg atgtgacacg tcttttgtca cgttcctttt ttatataacg
     6061 agaaagataa gacgaacaca tcacttattc tttcctttca tttataaaca ttgtagaata
     6121 aagaaagtac aacgaagtat tgtgaaaaaa cgtaataaat aacgaggaaa atacaagtag
     6181 gaggtaagct gtgaaagaat ttttgaaaaa ttgggggatt ttgatccttg tattagcggc
     6241 tattttatta gctagagtgt acgtgtttac accagttact gtaaacgggc attcgatgga
     6301 ccctacatta agtgatggac aacgattgat ttcatctaag atctcaaact atgaacgaat
     6361 ggatattatt actacaaagg aaccggggga tgaagaacgg atgattgtta aacggatcat
     6421 cggtatgcct ggagatacag tcaagatgga aaatgaccag ttgaccatta atggcaaaaa
     6481 gtatgatgaa ccttatctgg atgagttcaa aaaagaattt tcagaagata agttacaagg
     6541 agaatatgct tatagctcag gattccaagc acaagcagaa agttcatcca cctttacgag
     6601 tgactttgaa tatactgtgc caaaaggaaa gtatcttgtt ctaggcgata accgcttgat
     6661 ttcaaaagac agccgaatgt ttgggttagt cgacaaagat atgatccaag gaaaagttgt
     6721 tttccgttat tggcctcttt cagaaattaa aatcatgtga tgaaaaaata aaaagaagct
     6781 gtgacatgtt ttttgtcaca gcttcttttt ccgaaaattc cttcttattt cttggagttg
     6841 ctcacttttt ttgcaatctc attttaagct ttttggctga tggataagaa aagcgaagcg
     6901 tttttgttca taaatagctt ttccccacga tggaaggtat gactagtagc agagacaaag
     6961 cccgtttttt ccaatcgatt attcaattct tcttggctaa agccattatg gactttcgga
     7021 tgactaattt gttcattctt gtcaaagtct acgatgatca attgaccgcc aggagctaaa
     7081 atttcataaa gttttgtaag aatattctcc gtatcaggaa tgtgtaaaag tacaagtgat
     7141 agaaggatga gattagcttg gacagcagga aattcgacag aagcatcagc gtggatcgtt
     7201 cggacatttt tcagatctgc tgcttggatc ttttcttctg ccattttcag catagtttct
     7261 gaagcatcgg caatgatcag ttctttgaat ctttccgcaa gcggtaaact aacaagccca
     7321 gttccgcctc cgtaatccag caggactttt tggtggctgt cgcgcggtag ataagtagtt
     7381 agttcttcgc gaataatctt ggctaatgct tgacggtcag gggaatcata atggttagcg
     7441 atggaatcaa aaatattttt tgtcatcaaa tagctcctta cgtaaaactt tgaaatttta
     7501 acttattata gcacgtgaaa agaaagaaag catgctatac tcaattcaaa aagggagaat
     7561 ctagaaagaa tatgccgata tcgtttgtaa aagatagaga ggaaaaagga aagtgtgtcc
     7621 gagaaatatt actagacttg cctgagtggt ttgggcttcc tgaatcaacg gaaaaatata
     7681 tcgaggaatc aagtaaacta cctttatggt gtgaaaaaag aaaagaagaa tatttaggct
     7741 ttatcactct ttcacagaca agtgaagata ctgccgaaat ctattctatt gtatgggaat
     7801 aaaaaaagac tatcatcacc aaggattagg aacaaaactt tttaaagaag cagaaggtta
     7861 cgcagcaaaa cattacaaat atttgcaagt gaagactgta gacgaggggc actactctat
     7921 atatgatcaa actatttgtt tctacgaatc attaggattt tcaaggttgg aagtttttcc
     7981 aaatttatgg gatgaatgga acccatgttt agttcttgtc aaaaaattgg aacaaaagtg
     8041 agcaatagat ttaatactaa tctgtgcttg atgaaaattc tcactgtaaa aaatgctgaa
     8101 aatcaagtat aataccatag gaacaaactg gaaggtgaaa aagagcatgg cacaactatt
     8161 ttttaagtat ggcgcaatga atagcggcaa gacgatcgag atcctaaaag tcgcacataa
     8221 ttatgaagaa caaaataagc cagttgtctt aatgacaagc ggtattgata caagagatgg
     8281 tttaggcgtt gtttcaagcc gaatcggact gaaacgtaat gcgatgccga tatttgaaga
     8341 aacagacgta tttgacgtaa ttcagaaaat ggaaagcaaa ccctattgtg tgctgatcga
     8401 tgaagcgcaa ttcttaaaaa agaaacatgt cattgctttt acgagaattg tggacgaatt
     8461 ggatattccg gttatggcat ttggtttgaa aaatgatttt cgaaacgagt tatttgaagg
     8521 atcaaaatat ttattgcttt atgcagacaa aatcgaagaa atgaaaacaa tctgttggtt
     8581 ctgccacaaa aaagcaatca tgaatttaca ttatattgat ggaaaccctg tttatgaagg
     8641 cgatcaagtg caaattggcg gaaatgaagc ttattacccc gtttgtcgaa aacattactt
     8701 tcacccatca atgattacag aaggagaata agcatgtacg atcaattaca agcaattgaa
     8761 gaccgttatg aagagcttgg agaactttta agtgacccag aagtgatttc tgatacaaag
     8821 cgttttatgc agctttcaaa agaagaagca aacacgcgcg aaacagtcga agtttatcgt
     8881 cgttataaag aagtagtaca aggaatcacc gatacagaag aactgcttgg tgaaaaactg
     8941 gatgatgaaa tggctgaact agcaaaagaa gaattatctg aattaaaaaa agaaaaagaa
     9001 gtcttagaag aaaaaatcaa gatcttgctt ttaccaaaag atccaaatga cgataaaaat
     9061 atcatcatgg aaatccgtgg agcagcaggc ggagacgaag cagcattatt cgctggcgat
     9121 cttttcaata tgtaccaaaa gtatgctgaa gcacaaggct ggaaaacaga agtgatggaa
     9181 gctaacgtta ccggaatcgg tggatataaa gaagtgatca tgatgatcac cggagacaac
     9241 gtatattcga aattaaaata tgaaagtggt gcgcaccgcg tccagcgtgt tccttcaact
     9301 gaatcgcaag ggcgtatcca tacttccacc gcaacagttg tcgtgatgcc agaagctgaa
     9361 gaagtagaga tcgatattga agacaaagat atccgtacag atatctatca tgcttcaggt
     9421 gctggcggac agcacgtcaa taaaacagca tctgctgtac gtttgactca cttaccaaca
     9481 gggatcgttg ttgctatgca agatgaacgt tctcaaatca agaaccgtga aaaagcaatg
     9541 aaaatcttgc gtgctcgtgt gtacgataag atccagcaag aagcacaaag cgagtatgat
     9601 gccaatcgaa aatcagcagt cggaactggg gatcgttcag aacggatccg gacgtataat
     9661 ttcccgcaaa atcgtgtgac tgatcatcgt atcggattaa ctatccaaaa attagatcag
     9721 attttagcag ggaaattaga tgagatcgtt gatgcattga tcatgtatga tcaaacatca
     9781 aaactggaag ctatgcaaaa tgggtaaaat gacctatcga gaagtcctgt cacgggcttc
     9841 ttctttttta gaggatcatg ggaaagaagc atatagtatc caatttttat ttttggaacg
     9901 aaaacaatgg aaaaaacttg attggctcct tcatatgaac gaagagattt cagaagaaga
     9961 acagcggttg atcgaaaccg atctgcgact tctgcttgca gatcatccac ctcagtattt
    10021 gctaggatat gcagattttt atgatcatcg gttaaaggta actgaagcaa cactgatccc
    10081 tcgaccagaa acagaggagt tagtcgaatg gtgtttagac gagacgcctg gtgtaccgtt
    10141 agaagtgata gatattggga cagggactgg agcaattgct attagtttga aagcagcaag
    10201 aaaaaattgg catatatctg ctgtggatct ttcagaagaa gcattagaag tagcgaaaga
    10261 aaatgctcag aaagaaggaa cgaaaatcag tttttatcat ggagatacat taggaccagt
    10321 aatggatcag caatttgatg tgattatttc taatccgccg tacatcagtc ggaatgaatg
    10381 ggaactgatg gatgaaagtg tccggtcatt cgaacctaaa atggcccttt ttgctgagaa
    10441 cgatggatta gctatttatg aaaaaatagc agttgaagca ccaagcgtac taaaatcaaa
    10501 tggaaagatt tttttagaaa tcggatttcg ccaaggtgaa gcagtaaaaa aaatatttca
    10561 gcaagcattt ccagataaaa aagtggcgat aaaaaaggat ctttttggca atgaacgaat
    10621 gatccaagtt tatggttgaa gttgtggatg aaaaattttt tatttgtttt tttattataa
    10681 aaaaacactt atttgacaag gatgtaaacg actttttggt ttatcaacaa gtttatccac
    10741 tattgacaaa tagattatcc acaaacagtg gaaaacttga ggataaactc agacaaaata
    10801 agaatgtatg aaaaaggggt tgtggataaa ctgtggaaac gaaacgatat gatgaaacag
    10861 aattgcaaga ggcagccgaa gcactgaaag aaggagaact tgttgctttt cctaccgaaa
    10921 cagtatacgg attgggcgcc aacgctcttt taccaaacgc tgtcaagaaa gtgttttctg
    10981 taaaagggag accgcaagat aatccattaa tcgtccatgt cgcctctttt gaacaagtaa
    11041 aagagtatgt ggacaacttt catccggcag cagagaagat tgtgaagaac ttctggcctg
    11101 gaccattaac tttgatattt aagatcaaaa aagacacttt gccctcagtt gtgacgggag
    11161 gattatccac agctgcattt cgtataccgg ataacaaaaa aacactagaa gtaatcgaac
    11221 tttccggtgt tccgcttgtc ggtccaagtg caaatacgtc gggaaaacca agtccaacga
    11281 ctgcagatca tgtatatcat gatctacaag gaaaaattac cgggattatt gatgatggag
    11341 ctacgcgaat tggtgtagaa tccactgttc ttgatttaag tgatccaaca gccatgccta
    11401 tgattttacg accaggtgca gtaacgaaag aacaaatcga agcagtcatc gaatctcctg
    11461 ttgctattga tcagcatctt gtaaaagaaa atgaaacacc aaaagcccct gggatgaaat
    11521 acaaacacta ctcacccgat acacgtgttc tgatggtcag agatggcgat tggtcaactg
    11581 cagttcaatg ggcaaaaaat aagaagatcc gtgcaggtgt catagcaagc cccgaaattg
    11641 cggatcaagt gcggacagat actgcagctg tttatatgta taacgacaac tcagtagaag
    11701 cggcggctaa aggattgttt gcaggtctaa gaggattaga tgaaccaaca cttggattag
    11761 atttgatttt tgtacaagtg tatccagaaa ctggattggg gaatgcttac atgaatcgct
    11821 tgaaaaaagc agcaggacaa aattattttg aaaaatgatc aattggttat tgtcgcattc
    11881 ttttagtatg atacaatgct atcaagtaaa tcttctatca gtgaacgaaa aactaagcgt
    11941 aactaatcgt aatagaagag atacgaatat ttggcaattt gtttttgatg ggaaaaataa
    12001 aattgtagga aaataaaaag gagctgttgt ttgtggtaga ttacaaaacg tttgaccctg
    12061 atctttgggc tgcgatcgcc aaagaagaag aaagacaaga acataatttg gagctgattg
    12121 cctctgaaaa ctttgtctcc gaagcagtga tggctgcaca aggaagtatc ttgacaaata
    12181 aatacgcaga aggttatcca gggcatcgct attatggtgg gtgtgaattt gtcgatatcg
    12241 ttgaaaattt agcgattgac cgtgcaaaag aattattcgg agcgaaattt gcgaacgtcc
    12301 agcctcactc cggctctcaa gccaacacgg ctgcttatct cgctttggta gaaccagggg
    12361 acacgatctt aggaatggat ctttccgcag gcggacatct aacacatgga tcaccagtca
    12421 acttcagtgg caaaacctat cactttgttg cttacggtgt tgatccgaca acagaagtta
    12481 ttgattataa tgtggtacgt attttagcta gaaaacatca accaaaattg atcgtagcag
    12541 gtgccagtgc ttacggacga acgatcgact ttgcgaaatt cagagaaatc gcagatgaag
    12601 taggcgcaaa actgatggta gatatggcac atatcgcagg attagtagca gcaggacttc
    12661 atcctaatcc agttccttat gcagatatca caacgactac cactcataaa acattgcgtg
    12721 gccctcgagg cggcatgatt ttgacaaacg atgaagcatt agcaaaaaaa ataaatagtg
    12781 cggtatttcc tggtattcaa ggcggccctc tagagcatgt gattgcgggt aaagcagtag
    12841 cattcaaaga agcattagat cctgcattta aagaatatag tgaacaaatc atcgccaatg
    12901 caaaagcaat ggtcaaagtt ttcaatcaag caattggaac cagagtcatt tcaggggcga
    12961 cagataatca tctgatgttg atcgatgttc gcgagttagg tataaatgga aaagaagcag
    13021 agagcatttt ggacagtgtg aatatcactg taaataaaaa ctcgattcct tttgaaacac
    13081 taagtccatt caaaacaagc ggtattcgaa tcggcacgcc agcaatcact actcgcgggt
    13141 tcaaagaaga agatgctgta aaagtggctg aactagttgt caaagcatta caagcaaaag
    13201 atgataacgc tcaactagac gaagtcaaaa caggtgtacg cgaattaact gaaaaatttc
    13261 cgttgcataa aaaataaaaa tttaaattcc attagtaaac agaaaagttc aatgttgggc
    13321 ttttctgttt attttttggg aaaacggatt ctttgacaat atcggtgatg ctctctagta
    13381 tatgaggtgt aattttagtc ttcacactaa atctcaggga ggaaaagtca tgactgatcg
    13441 tatctcgtta gaaaaggaag cagtagcatt cagtgatgca aatgcgcctc atccgcgtat
    13501 ctatgaacta gcaccggaag aaggaagagt tttactagaa gaagtacaag aatcacctgt
    13561 gaacaaatat tccgtcgata ttgaagactt gatggtggat actggcgaat ggggaaaact
    13621 caatattcgt ctcgtacgac cagaagggaa tatggataaa ttaccagtta ttttttatat
    13681 tcatggagca ggctgggttt ttggcagtgc tcaaacccat gataaattga tcagagaact
    13741 tgcggttcgt acgaattccg tcgttgtctt tccagaatat agtcgatcac cagaagcaaa
    13801 atatccaaca gcaattgaac aaaattatgc tgtgttgcaa cagctgaata aattagccaa
    13861 gtcaaaaaat ctggatctcg agaatctaat cgttgcagga gattcagtag gtggtaacat
    13921 ggctacagtc atgacgatct taacaaaaga acgaaagggc ctcccaatat ccaagcaatt
    13981 gctgtattat ccagtcacaa acgctgattt tgatacagat tcctatcatg aattcggaga
    14041 aaactatttt ttgacaagag aaggaatgat gtggttttgg gaccaatata cgacgaatga
    14101 agaagagcgt gctgaaatca cagcttcgcc tttgagagca aatataaatg aactaaatga
    14161 tcttccttca gcaatgattt taacgggaga agcggatgta ttaagagatg aaggtgaggc
    14221 ttatgcgcgc aaacttcgtg atgcaggggt tcctgttaca caagtacgct tccaaggaat
    14281 catccatgat tttgtcatgg taaatgctat ggatcagaca aaggcaacgc gtgcagcaat
    14341 ggcattatct acttcttgga tcaagaaaaa agaataagct ttgcttgtcc gcaggaaaac
    14401 ttcttttcaa aaacggattt tcttaggaaa aatggcgagt ttgactagtc aatcacttga
    14461 ttttgtttta caattaaaaa gaaacgacag aacaaaggag agcttaaaaa atgggcaaat
    14521 ttcaagtgat cgatcatcca ttgattcaac acaaactaac tattattcgg gacaaaaact
    14581 gcggaacaaa ggtttttcgt gaagtagtcg atgaaatcgc tatgttgatg gcatatgaag
    14641 tatcacggga tatgccattg gaagacatcg tgatcgaaac accgatcact gaaacaacac
    14701 aaaaaacgtt gtctggtaaa aaagtagcga ttattccaat cttgcgcgca ggtattggaa
    14761 tggttgacgg tatcttggaa ttgattccag ctgctaaagt gggacatatc ggtctttatc
    14821 gagatgaaga aacattggaa ccacatgaat atttcgtcaa acttccagaa gacattgatg
    14881 cacgtcagtt gtttgtagta gatccaatgt tggcaacagg cggatcagca atcatggcaa
    14941 tcgatgcatt gaaagaacgt ggcgcgtcga acattaaatt tgtttgtttg gtagcagcac
    15001 ctgagggagt aaaagctttg caagaagcgc atcctgatat tgacatctat acagcttctc
    15061 tagatgaaaa attgaatgaa catggttata tcgttcctgg actaggggat gcgggtgacc
    15121 gtttgtttgg tacaaaataa gtaaatacga aaaagggtgt gacacaactt ttgtcacatc
    15181 cttttttggt catttttaac gtttgatgca gaacagcttt ttcacagctt tcgtttgcat
    15241 ataaaaaaac catcccaaaa atgcagagat ggtcaaattc aaatcttttt tagttctttg
    15301 tagttaacga ttactacacc cttactttgc gtcatcaagt tcgcattttc tgcagtttca
    15361 tcaatctcaa caacagcgga atttttcaat tgctttgaaa tcgttccagt ttgcgacttg
    15421 ccgtgaattg tgaacattac gtgagtattg atcttgaatt tttcaccaat ttccgatggt
    15481 acgatagttg tatcaaattt tccaaaagtt gccattttca taaaacctgc ctttcacatc
    15541 aattatacca cgttttatga aaaatatcat gaaattaaac taattttcca tcggactctt
    15601 tacaatcagc caaatagagt atataatttc ttttggataa ggccagctta gctcagttgg
    15661 tagagcaacg cactcgtaac gcgtaggtcg taggttcgat ccctatagct ggcattaaaa
    15721 gagaagacag atatatcaag gatttttaat ccattgatac atctgtcttt ttgtttaaag
    15781 gaaataaagt atgctttctt agcaatagag catgtattat ttctataaaa atttaggaga
    15841 ataaaacgac tagcaatata gctgtgaaat caaatatcac atgaactgcc caacttgtaa
    15901 tgatcgagtt gcttttaatg gcagcttggt tgaataacaa tcttgccacc ccttgtatca
    15961 aaaggatgtg tgctacagtg tgtaaaatat ttccattatc ataagtactg taatggataa
    16021 atccaaagat gattgctgac aagaaactag cgacaggaat gctgaactta ctagaaaaaa
    16081 tagcgagaaa atacactgag aacaattctt ctccaagtat catgataggc aaaataataa
    16141 ataataacgg gctgaaagcc tcatttattg gattgcctgt taaaccccat ttcaaaattt
    16201 gttgcaaaaa taccgagact gcggcactga ttactacatt gataaaaaaa tatttggcta
    16261 tatttttgac aggagcgaca ggtttcgaga acattttttt cgtatctttt ttaccaaaaa
    16321 caagtgtaaa tgctataaat ccagtgatag ttaaagaaaa aatgctaata atggatggcg
    16381 caaatagcaa ccctaacaaa ccgagtacaa cgacaatagt gcccaatatc ccttttttaa
    16441 gttctatttt ttttcctaaa atgttattca tgataataac tcctactatt cagtttttga
    16501 agatagagtc agtatacatg aagagttaaa ataggcaatg tttttttatg gatatttgta
    16561 ttgctaaaaa tttatcttat atattcattt tgattatact acttttattt gtaaaaattt
    16621 tctagcaaaa ccaagtgctt gcaactgatt aagcgtacaa ttttttagat gttccgagcg
    16681 tacttcaatc atttcaaagg agttgctact taaatcgata ttttttaaat cagtatcaaa
    16741 aaagctagca ttttctaaat cattagtaga aaacattatt ttagtgaggg aacagtctac
    16801 aaaatctgcg cttgataaga cagagtgctc aaaggtactt tcttttatgt ttgaaccaga
    16861 taaatttaca tagtccattt tacaattctc gaataacgtg ttcccaatat aactttccat
    16921 caatttagta cctgttaatt tacaattgac aaatttcacg cgatgcaaca tgctttttgt
    16981 caatatacag cctgaaaaat cacagttttc gaatatacag tcggtaatct ccattctttg
    17041 aaaatcattg gaagcaaaaa atgcatactt gaaaatagat ttgtaaataa ttggatggca
    17101 gattatttgg ttttcgatga cctctttttg tgaaaggata ttatacagtt caaaatcttc
    17161 gttttcatag atatgaaaaa aggatccttt attcaagctt gcttcattaa ctttaggaaa
    17221 aatcatattt aattacctcc attttcataa agtcatatta acaaaagcta aaccaactta
    17281 cattagcaga aaatgagata ggttttcgcc tttttcgata acgatagtgt cgctatctct
    17341 tgaaacgttc ttagaattgc cctgagagac acaaattagg cgtaattcta ataaaaatct
    17401 tagaataaaa atttttactg atttaattta gaatgttttt aaaataaaaa tcgttgccat
    17461 aacagtgtat tgaaaggttt taacaatcca gtaatgattt aaaaaaatct agatgtagcg
    17521 tatactttgt ttatagaatg tagtgggaag aaatatattt ttgggaggaa atcgtgatgt
    17581 ctaaaagtga agaaatagaa aacatggtac taaaattata tgatctcgtt ttaaatccag
    17641 agatcaaaga aaaggaacgt atacttttga tagacgcaaa gacaggctta gaaaaaggtc
    17701 agtattatcc taaagtcata aataatttgg aacgtagttt acgtccgtta gcaatcaggg
    17761 gagaattgtc taaaccagta tcaccgtttt atatggagat atcaacaata ggaaaatttg
    17821 aaaaagaatt aggtcgagga atggcttcgg caccgattac ttttgggcat ttataaaaac
    17881 gagttattca tctcaatgaa ttaaaaagta tagtcaatct cataatgcag gctaggttca
    17941 tttatttgaa cagagtctgt atttttttat tctaaataaa gaaacagatg tttctttata
    18001 ttgtatttta tcctttaatt aacacaaaaa cagctagtat aaactaataa tgttaattaa
    18061 aagtgtattt tatgaaacta tcgttattta ttaatgttgc atttttgtaa gttaaaaatt
    18121 ggaaatatag attgaaaaaa tgaaagcaat aagtaaaata aaatgaatat atgcgaaaaa
    18181 ataatttaca ttaggaaaaa ccttgtaaaa acagtttttt ggcatattta ttttttataa
    18241 atatttgtaa aataactatc aattttttag ttaaaagatt ggaaatgagt gggggaggaa
    18301 ttgaagaaag gatttttgag agatgatata gtaggtttta tttttagtta aaatagggga
    18361 gatagaaaaa atgaaaaagt gtagaaatat tattttatca atgttattta ttattactaa
    18421 tataacatca ctgattcctg ttcatgtcta tgcggatgca ggcagagata tcagcagtaa
    18481 tgtcacttcg ttgaccgtgg acccaacgaa tattacagat ggaggaaaca taaaagtaaa
    18541 attctcgttt gacgaaaaaa aacaaaatat ccaaccaggt gattatcttt ggatcaattg
    18601 gccaagtgaa ggaaatattc gcggtgaagg attccaaaaa gaaatcccat taatgattga
    18661 aaataaaaat gttggaactt taacggtcag aaaagattct gcgcaggttg tgtttaatga
    18721 aaatattaaa aacctagact cagtagaagg ttgggggcaa tttgagatac aggccagaaa
    18781 cgtaaccgat accggtgaag aaaatacggg accattcacc gtgacgagcg gtgataaaac
    18841 agctactgta aatgtgacaa agccagcttc tggttcttct tctagcgttt tttattataa
    18901 aacaggagac atgctacctg aagatactaa gcacattcga tggtttttga atattaacaa
    18961 taacggcact tatgttgaac aaccagttaa aatcagtgat gaaatccaaa gtggacaaag
    19021 attagatcca agtacgtttg aaattaatca aatacactta ggtgaacaga aggtttatag
    19081 aggagaagag ggaatccaac aatttttaca agatttcccc ggcgctacat ttaatttttc
    19141 agtaactgat aattacattg aaataactat accaaaaaac tttgtcaatc ttaggaaaat
    19201 aatggtgagt tataagacga tcatagaaaa cccagaacaa ataaattttg agaatcattc
    19261 ggaagcttgg tttaaagaat ttaataaacc tgctgttgat ggagaaagtt tcaatcatac
    19321 agttaaaaat atttcagctt ctggtggagt caacggtaca gttagaggcg aattgaagat
    19381 tttcaaatat atcaatgaca cagagattgg tatcccaaat gtgactttcg aattaagacg
    19441 agcagatgaa cagcctattc aaggacagtc tagtatcctg ttgacttcga atgaacaggg
    19501 agaagctagt atcaaaggcc tgcaagtagg agactatgtt gtaaaagaaa aagaagcacc
    19561 caattggatt gattttgatc cactaagttc aaatgaactc aaattctcca taaacgaaaa
    19621 tgatacagag ggagtcagtt tacctattta taacaagaaa aaggttacga acatcacagc
    19681 aactaaaatt tggaacggtg gaaccactcc aagaccgagt atttatttta aattattcag
    19741 agcaagtaca aacaattggg aaccagttcc tgatgcagaa acaaaacgat tagacaatgg
    19801 aataacttca gtgacttggg aagatatcca acagtatgat gatagtggaa acgaatatac
    19861 gtttaaagtg caagaagtag atcaaaacgg aaatgattat gtcccttcag gttatcaaaa
    19921 aattgaaaac gggctagtcg ttacaaatga gaataaagaa gtcatttcag tctcaggaca
    19981 aaaaacatgg gaagacaatg agaaccaaga cggcaaacga ccgacgacga tcacagtaaa
    20041 tctattagcc gacggtcaac cgatccaaca caaagaagta agtgaaaaag atgattggcg
    20101 ctatcgtttc acaaatctgc caaaatacag agacgggcaa gaaatcatct atactgtaac
    20161 ggaagacaac gtgcccgaat acagtacgac gattgacggg tataacatca aaaacagtta
    20221 tacaccggaa aaaacaaata tatctatacc aggtagccat ataacaccgt ggaaaaattt
    20281 tccagagaag acagagagag agaaaattag aaatctattc tctcaaaaat tgcaaatatt
    20341 tgctcataca ggagaatcca gcgaacaaag aagcaattat attagtaaga gagctgtacc
    20401 taaacagata acaaataaat caaaaagcat tcttcctaaa acaagtagta aaaaatctag
    20461 ttttgctgta atcattggtt tattgatagt aactatctgt gctgggatat tcttacaaaa
    20521 atataaaaaa gtttagttag aatataatat tttttgttaa atatgactga aatcaaaaga
    20581 ataaaattcc gatttataat cgaaaaaaga agcattttta tatatgcttc ttttttcgta
    20641 gaatcaataa atatggattt ggctaactat ggaagaatac tcgtattagt tttcagcgtt
    20701 catactagtt gttacattgt ttgattggcc aaaagaattt ctgatatatt ttgtgctaaa
    20761 taaagaaaaa gacgcttgaa ttgggaaata agaaaactac tctatcatta caaattttca
    20821 taaactggca gatgttctaa gtaaacaagt atcttttcaa agtcggaaaa atccataatc
    20881 aacgtagtgg tattgatatt tggatgaaag cctacggtat cttgacgatc aatagcagca
    20941 tcgatcacga cttggatttt tttctctttg tcgtgcatca atgctaatgg agtcactgta
    21001 cctgctggaa cgcctaggag gtcaggaagc tgttcttcag aaacaaaaga taagcgcttt
    21061 tcttttaatt gttcagctag ttgttttaaa tcggcgtgct tttcatcagg caagatgaca
    21121 agatagattt gttttccttt tcttgatttc aataatagat tttttacttg cggaccaggt
    21181 agggaaaaag ggacattttt gactgacgta atcgcaggat gatcgacttt ttgaaaagag
    21241 atacccagtt tttttagtag ttcataagct tcttgttcgg ttgcacgact catcgcgcat
    21301 caccctcctt tttttattag tgtatcataa aaaagagttg acaaatgaaa aataatcatg
    21361 taaattacac gtaaagttaa aacaaatgac atcgaaaaga agagtagccg ttaggtgttt
    21421 ttagagagtc tctggttggt ggaaagaggc agcagttaac cgtgaaacac atcttggagt
    21481 cgattttctg aagcgtatag taggaaaatc cggggagccc gttacagctg cggtcgttgc
    21541 tagatgacca gataaggctg gcttttccgt gaggagtcgg taaaaaaagg tggaaccacg
    21601 tgattaacgt cctttgatct tcggatcaaa ggactttttg ttttcatctg aacggcaacg
    21661 actgtgtgag gttttttctg caaggaaaaa ataaacagag gtggaaccac gtataatacg
    21721 tcctcttggc atttgccaag aggatttttt tattttaaag gaggaaaaga agatggagta
    21781 tttgattgaa gttatgccgc aattattagt aggagcactc acaacattga aattattttt
    21841 atttaccttg attggctcat taccattagg gattgtttta gcattaggat tgtctttgca
    21901 ttttaagccg ctacgctact tgcttcaaac atatgtatgg gttatgcggg gaacaccgct
    21961 gttgttgcaa ctgattttta ttttttatgg gttgccgacg attgggatcg tttttgatcg
    22021 tttcgaagca gcactcattg cctttatctt aaactatgca gcttattttg cagagatctt
    22081 tcgtggaggg atacaatcga ttcctcaagg tcaatatgaa gcagcgcaag ttttgcaatt
    22141 aagtcccttt caaacggtga cgaaaatcgt catcccacaa gtgacaaaga ttgttttacc
    22201 ttctgtaggg aatgaagtta tcaacttggt caaagattct tccttgatct atatattagg
    22261 tttaggtgac gtaatgcgtg ctgggaaaat cgcgatggaa cgcgacgcga ctttactgcc
    22321 tttgctaggc gtggcaatca tctatcttac attgactggt attctaacaa tcgtaatgaa
    22381 acaagttgaa ggaaaattaa attattaccg ctaactgata ggaggaagaa atatgattga
    22441 attgaagaaa gtgaacaaag catttggtga aaaaaaaata atcaaagatt tgaatctaat
    22501 cattccagat gggaaaacat tagctatcgt aggtccttcc ggtggcggta aaaccacgct
    22561 tttacgtatc ttggctggct tagaaagttc tgacagcgga gaattttatt tagacggtgt
    22621 accgttcaac ccattcgagc ttaaaatgaa agaacaagtt gtaggagtcg tattccaaga
    22681 cttccagcta tttccacatc tgaatatttt tgaaaacatt accttagcac caaaaatggt
    22741 attgaaacag acaaaagaag aatacaccaa aaaagcagaa gaattagcgg cttcattagg
    22801 gattagtgat ttattgaata tctatcctta tcagctttct ggcggacaaa aacagcgggt
    22861 agcgattgcc agagcattgg ctatgaatcc acgggtattg gcttatgatg aaccaacaag
    22921 tgctttagat cctgaattac gccagcaagt cgagcgtttg atcctatcat tgaaagaaga
    22981 tggggtaacc caaattattg tcacccatga tttagtattt gcagaaaatg tcggtgatca
    23041 attactaaaa gtttccccaa ttcattaaga aaggagaaga tagagatgaa aaaaaccagt
    23101 tttctattcg ctttgatcgc aggtcttctt ctttttgcag gctgttcgaa caaaaaaact
    23161 tcagcagata attgggcgac tatcaacgaa gagaaaaaaa tcgttatagg tttagacgat
    23221 acatttgttc ctatgggatt tagagataaa gacgggaagc tcacaggatt tgatattgat
    23281 ttagccaaag cagtctttga acaatatggg attacggtag actttcagcc cattgactgg
    23341 tcaatgaagg aatttgaact gaacaatgga acgatcgatt tgatatggaa cggctattcc
    23401 aaaacgccgg caagagaaaa gaaagtgcaa tttacaaaac cttatatgga aaacgatcaa
    23461 gtgctgatca cacctaaaga atcaggaatc acaaactttg gacaaatgaa taataagaga
    23521 ttaggtgcgc aaaatgggtc atctggttat gatgtattta cgaaacaacc agaagtatta
    23581 aaagagatag tcaaaaacca agatgctgtt ttgtatgata gttttaatga agcattgatc
    23641 gatctgaaaa gcagacgggt cgatggtctg ctgatggata aagtatacgc agactattat
    23701 ttgaaacaaa gaaacgaact agaagacttc aacataacaa aaggttctta tgagagtgag
    23761 gattttgcag ttggtgcacg caagtcagat agtacattag tgaaaaaaat caatgaagcc
    23821 ctagatcaac tagagaaaac aggtgaattc caaaaaatat ccgataaatg gtttggcgaa
    23881 gatgttacgc cgagaaatta acaaataggg gactgtgaca aaagacgtgt cacagtccct
    23941 ttttccgaat aaacagtgtt ctcctgccaa ctccttgtga ctcggagctg aatggcaggc
    24001 tcacaacctc ttggtaaacg gtgttcaaaa gccagttttt cggtattaag ccaaatttat
    24061 gcaaaaatgt agaaagccat tttcacaaaa tttttcttac tactcgaaac taagcgactt
    24121 tttcacaacc tcctttacat aattttattt tgttgtggaa ggggtttcgt gttattctaa
    24181 aagaggaacg attgaaggtt ataggaaagg aagagatgaa tggaacacaa agaacttacc
    24241 tcatttccaa aagattttct gtggggctct gcttctgcag cgtatcaagt agaaggagct
    24301 tggcaagaag atgggaaagg agaatcagtc tgggatcgat ttgtacggat acctggaaag
    24361 acatttaaag gaacgaacgg tgatttggca gtagaccact atcatcgtta taaagaagat
    24421 attgctttaa tgaaagaaca aggtctgaaa gcttaccgct tctctgtagc ttggacacgg
    24481 atttttccta atggacgagg agaagtcaat caagctgggc tcgcttttta tgagagattg
    24541 atcgacgaat tgattgaaaa cgatattgaa cctatgttga ctttatatca ttgggatctt
    24601 ccacaagcat tgcaagatga atataatggt tgggaatcac gtcagatcat tgaagatttc
    24661 actcattatg cagaaacatt atttgaggca ttccgcggga aagtccatta ctggattagt
    24721 ttgaatgaac aaaatatctt cacttcatta ggttatttgt tagcagcaca tccgccaggt
    24781 gtgacagacc cgaaacgaat gtatgaagtt aaccatattg ctaatttagc aaatgcatct
    24841 gtcatcaata aatttcacga gttagaaatg cctggaaaaa tcggaccaag ctttgcgtat
    24901 acgccaaatt atccaattga cagtaatcct gaaaatgttc tggctgctga aaatgcagaa
    24961 gacctgatgg ccaattattg gatggatgtc tatatgtggg gaaaatatcc gattgctgcc
    25021 atgaggttct tagaagaaaa aggatgggca ccaacgattg aagctggcga tgcagaattg
    25081 ctagaatctg ctaaaccaga ttttcttggg atcaattact atcaaacggc gacgaatgca
    25141 ttcaatccat taaacggagt tggtgcagga aaaatgaata cgacaggaaa aaaaggttca
    25201 tcagaagaaa ctggagttcc tggaatgtat aaaaaagttg agaatccatt tgtcgaacga
    25261 acaaattggg actgggagat tgacccagaa ggattaagga tcggactgcg tcgtatcaca
    25321 agccgttacc gcatgccggt actgattacg gaaaatggct taggagagta tgacaagttg
    25381 acagaagata aacaaatcca tgacgactat cgaatcaatt acttacaaag ccacgtcaaa
    25441 gccatcaaag aagcaatttc ggatggagca gaagtcctag gctattgcac ctggtcttat
    25501 acagatttgc ttagctggct gaacggttat caaaagcgat atggatttgt atatgttgat
    25561 caagacgaaa cacaagaagg atctttggaa cgatataaga aagacagtta ttactggtac
    25621 caaaaactga ttgaagaaaa tggagagaac ctttagttca catacttaaa acaagaaggt
    25681 acggctggat atggccgtgc cttttcttga taaaatcatt tagaaattaa gaaaaactgt
    25741 aaaataagct gaaaaatgaa agaaagcgtc agttctttca aacaaaactt tagttccctt
    25801 actttttttt gtataatgaa acttgatgaa atgagggata ataaatggca caaaagaaac
    25861 ggcctactaa aaaaaggaaa aagacgaaaa aaacgaaaaa gcaaaaacag cagcaggaac
    25921 aaatgctgac gattggtgtt gggtttgcct tgattttatt tgctgtcttc ggctttttaa
    25981 aattaggttt tttaggaata ttgattgcaa acggctttcg gatcattgca ggaaatactt
    26041 accaaatcct ctgtctttta ttagccgtat taggattttg gattgtcatt aagaatacag
    26101 agttttcaat tggtaaaaac cgacgctggt ttggcggcat actcttttat ttcggtatct
    26161 tattattgtt acatgcccat ttatttggca aactccatac tggggaacca aatatcatgg
    26221 ggacgacatg ggatttgtta gccagtgata taaaacaaag tcaagtagac aataacgttg
    26281 gtggtgggat gattggagca atcctttatc attttactta cttcttgatt gcacagcctg
    26341 gaagttattt agcagcagtg ctattactgg caggaggagc attcctgttc agtaatctgg
    26401 aaggctatca gctgttaaat ggtatccaat caattggaga acgagtacag gaattattgg
    26461 aaggtgatcc tgccaagcaa gctcgaaagc aagcggcaaa ggaagagaga atgaaacagc
    26521 gcgcagaagc gaaagaagca aggcgcttag ctgcaaaaga agctgcagaa aaagaagctg
    26581 cagaatatga gaagaaaaaa gcggtgagcc agcaaaggga aaatactgct gatgaatggc
    26641 aggaaccaga aaatacagag ccggagcagc taagttttgt tccaatcgac agttttcaag
    26701 aaaatatcca tcctgcgaat ctagagaaac cagtaccaga tacaccaaaa cagaccaata
    26761 cagcagaagg tttttcagat gagttgccag aggatgacgg tacctcatta gaatttgaga
    26821 ttgaagcaga acaggaaaat caagactatg aattaccgac agttgatttg cttgattcta
    26881 taccaactgt ggatcaaagt gatgagtata aaaaaattga aaaaaatatc ggcgtattag
    26941 aacaaacttt ccaaagtttc ggtgtcgatg ccaaggtcgt caaagccagc ttaggaccat
    27001 ccgtcacaaa attcgaagtc cagccggctg taggggtaaa agtaagtaaa attgtgaact
    27061 taacagatga tatcgcgctt gctttagcgg cgaaagatgt ccggatggaa gcaccgattc
    27121 caggtaaatc actgattggt attgaagtac caaatggaaa gatcagtatg gtttccttta
    27181 gagaaatcat cgaagcacaa ccaaaccacc cagataaatt actagaagta cctttaggac
    27241 gtgatgtttc tggacgggta caaacggctg atctttcgaa gatgcctcac ttactcgtgg
    27301 ctggttcgac tggtagtggg aagtcagtag caattaatgg gattatcaca agtatattaa
    27361 tgcgtgctaa gccccatgaa gtaaaactga tgatgatcga tccgaaaatg gttgaattga
    27421 atatgtacaa cggcatacct catctgttga cgccggtcgt gacgaaccct agaaaagcag
    27481 cgcaagcctt acaaaaagta gtacaagaaa tggaagaacg atatgaaaaa ttcgcggcaa
    27541 ccggagtaag aaatatttct ggttacaatg aatttgttca acagaaaaac ttggaaaacg
    27601 gaacgaaaca tccaacctta ccattcatcg tagtgatcgt agatgaatta gctgatttga
    27661 tgatggtagc cagcaatgaa gttgaagatg cgattattcg tttagcgcaa atggctcggg
    27721 cagcggggat tcatatgatc ctagctactc aacgtccaag tgtggatgtt atcacaggaa
    27781 tcatcaaagc aaatgtacct tccagaatgg catttgcggt atcaagcggt acagattctc
    27841 ggacgatcat tgattctaat ggggcagaaa agctcttagg gcgaggagat atgctattct
    27901 tgccaatggg tgagaataaa ccgatccgtg tgcaaggagc attcatttct gaccacgaag
    27961 tagaacgggt cgttcaattt gttacagatc agcaagaagc tcattatgaa gagaaaatga
    28021 tgccgacaga tgaagttgaa acgacaggtg ctccagaaca gccacaagat gagctgtttg
    28081 aagaagcaaa agcacttgtc gttgaaatgc aaacggcaag tatttccctt ctccaaagaa
    28141 gatttcggat cggttacaac cgagcagcac gtttagtaga tgaactggaa gctcatggag
    28201 ttgttggccc gtcagaagga agcaagcctc ggaaagtatt cattgagcag gaagaaacat
    28261 cagaaacgtt gccggacgat aatgacatgt aaaacttgtg tgatgaaggg ttgaaaaacg
    28321 aataaccaat aaaaagacaa ggcatgatga taccaaaaga aaaaatggtt tttttccatc
    28381 ttttctaata cggtatgatg tcttgtcttt ttagtttttg tgagattaaa gttctattcg
    28441 atttatttgt gaagtattgc attaaggaaa tgaatcatgt atagtatgta gcgaaacttt
    28501 gagaaaaaga gggaaaatac tttggaaaaa cagtccattt atggcttgac gaatgaagaa
    28561 ttaatcaatt ggtttataga aaacggcgag aaaaaattcc gagctgccca agtttgggaa
    28621 tggttgtatc aaaaacgtgt aagtaatttc acagaaatga cgaatctatc gaaacaattg
    28681 atcgaaaaat tatcggagca ttttatcatc aatcctctaa aacagatggt cgtccaagaa
    28741 gcttcggatg gtacagtaaa atatttgttt gaactccctg ataaaaacat gattgagact
    28801 gtactgatga gacaagaata tggcttgtca gtttgtgtga cgacacaagt aggatgtaat
    28861 atcggctgta cgttttgtgc aagcgggctg ctcaaaaaga accgtgatct gactgctgga
    28921 gaaattgttg cacagatcat gatggtccaa cattattttg atgagcgcaa tcttggcgaa
    28981 cgcgtttcac atgtcgttgt aatggggatc ggtgagccat ttgataatta cgacaatgta
    29041 atggactttt tgcatatcat caatgatgcc aaaggattgg caattggtgc tcggcacatt
    29101 acagtttcca ctagtggatt agcacacaaa atcaaggaat tcgctaataa cggcttgcaa
    29161 gtcaatctgg ctatttcctt gcacgcgccg aataatgagg tgcgaacatc gatcatgcgg
    29221 atcaaccgaa gtttcccaat tgagaaattg atggaagctg tggatgagta tttagagaaa
    29281 acaaaccgtc gaatcacgtt tgaatatatc atgttgaatc aagtaaatga tagaccagag
    29341 catgcgcaac aattagcaga tctattaaaa gataagaaaa aattagcata tgtcaacttg
    29401 attccatata atccagtcag tgaacatgat caatattctc gcagtccaaa agctgatgta
    29461 ttgagatttt atgatgtatt gaagaaaaac ggcgtaaact gtgtgatacg taaagaacat
    29521 ggtacagata ttgatgcagc ttgcggacaa ttgcgaagca agcaaatgaa aaaaacagtt
    29581 gccaaataat cgtatcctac tcgttttttc aattaccata aaaggagcag ttttcttaat
    29641 taaggaactg ttcaacttaa ataagagaaa agattctata gcgaaagcta taaagctttt
    29701 tttgacaaga aaaaccctca tcaagcaaag aaatgtcctc aatttgatga cagcctgctt
    29761 gatgggggtt ttagcaatta tttaactgat tttcttatat ccttgctggc tttcttgtgt
    29821 agcatgataa gtttctacgt caagaatggc ctgtttaaat ttttctcggg tgatttcata
    29881 aggcacatgt ttaatatcat ttgttgccat ggctttatct aagattgctt ctaaatcggt
    29941 cgtgacattg agattcatgt cggttaacga tactggaagt tggttctttt tcataaacac
    30001 atagatttta tcaaacaaat cgaactgctg atccatcatc aataaggtca gtacaccata
    30061 actgacagat gctccgtgaa ggtatccctc cattttttct agaacagtcg taccgtaata
    30121 gaatgagtgt gccatagcag aattatagtt attgttaact aaaacagaaa ccaatccggt
    30181 agtaacaatg atatccgaaa cgacttgttc aattgcatat gagggacgat cgtcggcact
    30241 atctttcaat gcttgcgtac cataagtcaa gagacgatca atgcacattt ttccgatttg
    30301 gattcctaat ctatccgtgt agcctagatc atcgccacga gcagaaaaag tagattcgac
    30361 ttctttggat aaagcatcgc caatacctgc ccataagtat ttatcaggtg cttcggcaat
    30421 aattgctgta tcaatgaagg tgtgtacagg tggttttgaa ggaaagaaga gtccgtccat
    30481 tacgccttct tcgttataga tgacacatac cgcagtgacg ggcgaacagt tcgaaccaat
    30541 agtgggaaag gtgaagactg gtttagctag tttttcacca atgactttta cagtatcgca
    30601 agcacggcca ccaccgactg caaacaggac gtctgctttt tggacacttt catgctggat
    30661 caactgttca atatttccat aagttgaatt acccccgtac cagagactgg cgacaacctc
    30721 tatttcctgt gtcaaagcta cttttatttt gttttctgcc tttgaaagtg cagtcttccc
    30781 tccaatcagc actacttttg tcccatattc tttgacgatt ccatttgctt tttcatacgc
    30841 atctgttcca atggtataat ttggtaagaa aacactttga ctcatattca tttccttctt
    30901 tcttcgttga aacgggttaa aattttaaag agtgatcgat ctgactgcgg ctgtagatgg
    30961 agtagaggtg aacctaagac aggataagtg atgaataagg tggcatgaac accttgaaat
    31021 catcaataag tatcctaaaa acgaacaagt acaaaaacat tgaaaacgac aataatgaat
    31081 ttttgttcct cttagtattt ctaccgattc cctttgcttt tttgtaatta tctaaaaatt
    31141 ctaaaaatta agattattat atgaaaacag gttttatttg tcaattcata attggttttt
    31201 tttaaagcaa aagataatct atatcatgat gaacaaacag agttttttcc tccaattgat
    31261 ggctttcctg atctttccta ttttgaataa agtgtttctg tataattttt ttattttata
    31321 agtaagataa ataatgaaag aatagagata ctgattggta gctaaagatt tttgagcgag
    31381 aacatttcgt tttttcaaaa ggactgttag aataagcaag aacaaggggg aagacgtatg
    31441 ataatcagtg aatttgaccg taataatcca gtattgaaag atcagctttc tgatttactg
    31501 agactgactt ggccggaaga atatggagac agctcggcag aagaagtaga agaaatgatg
    31561 aatccagaac gaatcgcggt agcagcggta gaccaagatg agttagtagg atttattggt
    31621 gcaatccctc aatacggtat cacaggttgg gaattgcatc cattagttgt agaaagctcc
    31681 cgacgaaaga accaaatagg tactcgatta gtcaattact tagaaaaaga agtagcttcc
    31741 agaggaggaa tcacgattta tttaggtacg gatgatttag accatggaac aacgttaagt
    31801 caaacggacc tgtatgagca tacatttgat aaagtggctt ccatccagaa ccttcgtgaa
    31861 catccgtatg aattctatga aaaattaggt tataaaatcg taggtgtctt accaaatgca
    31921 aatggctggg acaaaccgga tatttggatg gcaaaaacga ttattcctcg accaaattct
    31981 caataataaa aagaggttgt gacagaagta atcagcttca agaaataaga aggaatttac
    32041 gaaaattact tcttgaattt ttgtgaaatt ccaacttatt tccgaagaag ctacttttgg
    32101 aacaccgtgt ac
//
LOCUS       DACGMI010000036        29015 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.037, whole genome shotgun sequence.
ACCESSION   DACGMI010000036 DACGMI010000000
VERSION     DACGMI010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29015
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.037"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(48..1112)
                     /locus_tag="IXT46_001763"
     CDS             complement(48..1112)
                     /locus_tag="IXT46_001763"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAQ4947675.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(1109..2194)
                     /locus_tag="IXT46_001764"
     CDS             complement(1109..2194)
                     /locus_tag="IXT46_001764"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAQ4947676.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(2207..3184)
                     /gene="mvaD"
                     /locus_tag="IXT46_001765"
     CDS             complement(2207..3184)
                     /gene="mvaD"
                     /locus_tag="IXT46_001765"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAQ4947677.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQEIFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(3177..4121)
                     /gene="mvk"
                     /locus_tag="IXT46_001766"
     CDS             complement(3177..4121)
                     /gene="mvk"
                     /locus_tag="IXT46_001766"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAQ4947678.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            4443..5096
                     /locus_tag="IXT46_001767"
     CDS             4443..5096
                     /locus_tag="IXT46_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAQ4947679.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVRV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVAI"
     gene            5181..6086
                     /locus_tag="IXT46_001768"
     CDS             5181..6086
                     /locus_tag="IXT46_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAQ4947680.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(6088..6720)
                     /locus_tag="IXT46_001769"
     CDS             complement(6088..6720)
                     /locus_tag="IXT46_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAQ4947681.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            7040..7564
                     /gene="infC"
                     /locus_tag="IXT46_001770"
     CDS             7040..7564
                     /gene="infC"
                     /locus_tag="IXT46_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAQ4947682.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            7636..7836
                     /gene="rpmI"
                     /locus_tag="IXT46_001771"
     CDS             7636..7836
                     /gene="rpmI"
                     /locus_tag="IXT46_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAQ4947683.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            7889..8248
                     /gene="rplT"
                     /locus_tag="IXT46_001772"
     CDS             7889..8248
                     /gene="rplT"
                     /locus_tag="IXT46_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAQ4947684.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            8500..9837
                     /locus_tag="IXT46_001773"
     CDS             8500..9837
                     /locus_tag="IXT46_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAQ4947685.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            9885..12014
                     /locus_tag="IXT46_001774"
     CDS             9885..12014
                     /locus_tag="IXT46_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAQ4947686.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            11989..12678
                     /locus_tag="IXT46_001775"
     CDS             11989..12678
                     /locus_tag="IXT46_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947687.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(13086..13772)
                     /locus_tag="IXT46_001776"
     CDS             complement(13086..13772)
                     /locus_tag="IXT46_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4947688.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(13908..14102)
                     /locus_tag="IXT46_001777"
     CDS             complement(13908..14102)
                     /locus_tag="IXT46_001777"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947689.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(14152..14592)
                     /locus_tag="IXT46_001778"
     CDS             complement(14152..14592)
                     /locus_tag="IXT46_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAQ4947690.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(14596..15441)
                     /locus_tag="IXT46_001779"
     CDS             complement(14596..15441)
                     /locus_tag="IXT46_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAQ4947691.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            15590..17008
                     /gene="pepV"
                     /locus_tag="IXT46_001780"
     CDS             15590..17008
                     /gene="pepV"
                     /locus_tag="IXT46_001780"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAQ4947692.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(17065..18012)
                     /locus_tag="IXT46_001781"
     CDS             complement(17065..18012)
                     /locus_tag="IXT46_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4947693.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(18235..18585)
                     /locus_tag="IXT46_001782"
     CDS             complement(18235..18585)
                     /locus_tag="IXT46_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4947694.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            18785..19864
                     /gene="pepA"
                     /locus_tag="IXT46_001783"
     CDS             18785..19864
                     /gene="pepA"
                     /locus_tag="IXT46_001783"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAQ4947695.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            20008..20328
                     /locus_tag="IXT46_001784"
     CDS             20008..20328
                     /locus_tag="IXT46_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAQ4947696.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            20350..20814
                     /locus_tag="IXT46_001785"
     CDS             20350..20814
                     /locus_tag="IXT46_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4947697.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            21019..21624
                     /locus_tag="IXT46_001786"
     CDS             21019..21624
                     /locus_tag="IXT46_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAQ4947698.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(21663..22952)
                     /locus_tag="IXT46_001787"
     CDS             complement(21663..22952)
                     /locus_tag="IXT46_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAQ4947699.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            23380..23859
                     /gene="rlmH"
                     /locus_tag="IXT46_001788"
     CDS             23380..23859
                     /gene="rlmH"
                     /locus_tag="IXT46_001788"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAQ4947700.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            24062..24612
                     /locus_tag="IXT46_001789"
                     /pseudo
     CDS             24062..24612
                     /locus_tag="IXT46_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299296.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
     gene            24683..25852
                     /locus_tag="IXT46_001790"
     CDS             24683..25852
                     /locus_tag="IXT46_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HAQ4947701.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            26152..26844
                     /locus_tag="IXT46_001791"
     CDS             26152..26844
                     /locus_tag="IXT46_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAQ4947702.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKINNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
     gene            27272..27664
                     /locus_tag="IXT46_001792"
     CDS             27272..27664
                     /locus_tag="IXT46_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947703.1"
                     /translation="MLDDRLTCSNCGTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKR
                     KLSHGYFVSYELYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGN
                     ICPGFMDQIIENESIESIENYVPVDLPK"
     gene            complement(27837..28019)
                     /locus_tag="IXT46_001793"
                     /pseudo
     CDS             complement(27837..28019)
                     /locus_tag="IXT46_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            28006..28203
                     /locus_tag="IXT46_001794"
     CDS             28006..28203
                     /locus_tag="IXT46_001794"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947704.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            complement(28246..28821)
                     /locus_tag="IXT46_001795"
     CDS             complement(28246..28821)
                     /locus_tag="IXT46_001795"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAQ4947705.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
BASE COUNT         9297 a         5253 c         5681 g         8784 t
ORIGIN      
        1 tacttccgcc gtttgtacgt gtttagagcg tgagacaaaa gtgttcttta cttttgtccc
       61 acgctctttt ctgtgcgtct tccatacttc actaagtcga tccctcttgc ttcgcaccaa
      121 tccttcactg gtccggaaaa gatcagagat tgttggtgta gggccgcggt attcgttgcg
      181 ccgaccatag tataaagcag acgaagctct tcttgccatt gcttcatcag tataatagtt
      241 tcttctacgc cgtgattcat cagatgcgtc agtacggttc ctgaagtacc cacggcattt
      301 gcgccgagac aaagggcttt aaatatgtca taggcattgc ggatacctcc ggaggctagg
      361 atttccatag aagtgtctgc ttcatttgct tcaagcaatg aagagactgt cgattgcccc
      421 cagtcagcta aataactcag ttcccgcttg gagcgacggg cgttttcgat ctgggtgaag
      481 cttgttccgc ttcgaccgct gatatcaact gtatgaactc ctaaagcagc tagatcattg
      541 agcgtttctc ttgtcatgcc aaaaccgact tcttttacga tgagggggac gtcaatggct
      601 gtttgagttt cttgaataag tactttccaa ttggtaaaat cacggtctcc ctcaggcata
      661 accaactctt gaggtgcatt caaatgaatc tgtaaggcat ctgcgtgaaa caatcggata
      721 gcttctttgg ctctttcgac agaagtccct gcaccgatgt tggcaatgat tttcccgtga
      781 ggatattctt gtcgcataat cgtataagta tcggctaaag aagggacttt caaggcagcg
      841 ctgactgaac cagtggcaat catcaaatct gcttctcttg cgacgattgc aagatcttgg
      901 ttgatttttt ttgttttttc gcttccgcca gtcatcgcat tgatataaaa tgggctgctt
      961 agtgtaaacc caactgcctg tgtacttaga tcgacatcag aaactgctat ttgcggcaaa
     1021 gggttatgga tgatccgtac gaagtcaaat tcgttttttt gtttatcatg aaaggcttta
     1081 gctagtgaaa catgttcgtc ttttcgattc atcggttttc ctttctttga tcgctataga
     1141 catgtaacgg cagtggagtg atttctgctt tttcccatgc actcattaaa ggaagaatgc
     1201 cagatttctg gtcaacaatt acgattccgc aatcgccccc acctgcacca gaagattttg
     1261 cggctccttc atactgttca gctaaattac acaatttgtt caaagcaggc gtttcgatga
     1321 cgaccccagt gattgcagat aaatcatgca gtaattgtcg gttttttcga atcatctgtt
     1381 ggatcaacgt tacattattt tctttaaacc ctttgatcat ttcgttgaca cattctgtac
     1441 tattttttaa gaaaagctga taagccacca ttttatcttc tctcgaacgg tgaacttgat
     1501 cgaccaaatc agaagtagag gcagggctac ccgtccaacc aatcaataaa cgtaaatctt
     1561 caggagcaat caatggctca atggatagac ctggccaatc cagggcaagt aactcactga
     1621 tagaatgctg agtttcttgt tcttggagcc aaggatggtc gaaggttgag aaagcgatcc
     1681 agccaccata acagctagca gcgatgtcgc cgcaggaacc attatcttga actgctaaat
     1741 tggctagtgc tgcaatcttg aaaatctcca actgagataa attcaacgcg taaaaaacat
     1801 tcaaggcttt gaccgttgca acggtcacgg caccgctaga acccaatcca tatttccggc
     1861 catttgaact gtctaactca cttgttactt tcagatcata aaaggataaa agaatgtttt
     1921 tttcttgtgc atacttttca gtcaagcgaa tagcagcaag gatataatga aaaggatttt
     1981 cccgaatatc taaaactaat tctccgttgc gtcttgtcca acgtacaggc atcccactat
     2041 attgtgcaga ttggatactt ccgacttttc gtgcagattc tacagtgact gtcacgaatt
     2101 gatcgactgc agcgataact gctggatggc ctgtttcaac aactgcatat tctccggcaa
     2161 tatagagttt gcctggtgca gatacttcaa tcataaaaat ctccctttat tcaataatcg
     2221 caattcctgg accagcatgt gcagtaatta cttgttcttt gctaaataat ttggtaaata
     2281 tttcttgtac ctcagataaa tggctgtttt ccactaaaac tttgacatta gggccagcat
     2341 ccatcgtaaa gtagcatgga atgccttgct ttctcaattg tcgcaccgca tccatcgctt
     2401 ttaagctgtc aggagaccag taagtgaatg gaggctgggc agctaaagtc gttccatgca
     2461 tttttagtcc gtttctttcc atcgtttctc cgagaagttg gaaatctttt gttttgattg
     2521 cttgtttcaa ttgatataga tccccttcaa cggaatctaa ccagccttga taaaaactgg
     2581 atgtttcgac tgtccgacgc atcccatttc tgctggacac ttcttttttc tggtcgttga
     2641 tcaaaacgaa aaccattgct aaatcgtctt cgaaagaatc ggaagggact ggcttagcgt
     2701 aagaacttaa gtcgtcatgg cctttttccc attcgacgaa accaccgaaa atacttcggc
     2761 aagctgaacc agacccgcgt cgagcaaatc ttgaaagaga gagatcatct aatccaagct
     2821 taagagcagt attgcaagcg cctgctaaag cagctagccc gctggcagag gaggctaatc
     2881 cagctgcggt aggaacgaaa ttctgactga ttactgaagc ttttagtgag aggccggctt
     2941 ctttacgaaa aaggtcaaga aactgactga ctttttttgt tgctttttcg tcttgcaagg
     3001 tgccatctag ataaaattca tctaccatat agctatcaga aaagatgact tctgtctctg
     3061 tataaaatgc atccaatgtt aacgaaaggc tgttgttcat tggaaggatg agttcttcat
     3121 ttttcttacc ccaatatttg attagagcaa tgttggtata tgcgcgtgct ttgcctttaa
     3181 acataggtat gtactcctaa tccttgtatc caagtttcag cagcacccgc atcttcaagt
     3241 gcttgactga tttcttgggc ttttgttttt gtttgtgcta atgcaatcat acagccaccg
     3301 cgtccaccgc cagttaattt ggcacccaat gccccggtat cttttgctgt ttggatcaat
     3361 agattaagaa aatcattgct gattgtcagc ttttccagaa gtgattgtga ttcatccatt
     3421 gtctgtgcca acgtttctgg tgaattttca atgattgctt gttttgcttg cttcgtcaag
     3481 tatcctaatt tttggatcat ttgtccagtt tcatgaggct gggtttcaaa gaggtgagcg
     3541 acatctttga cggcttctct tgtttgtcct ttgattcctg tatcagcgac aatcaaaaaa
     3601 gcatcgatgt tcaaagaaaa gtagtcgaaa ggatgccctt ttgtaaaata aatcggctgc
     3661 aagctgctag tagcggctgc atcgattcca ctaggattac cgtgggcgat tttttccgaa
     3721 agctggacat tttctaatag tatttcacga gacaaaggaa atgctaagta atcataaaaa
     3781 gcacgagtga ctgctgtggc gactgcagcg cttgatccca ttccacgttc agcaggaatc
     3841 gtgctttcaa tggtcagttg caagtttttt tggatgtcat gctgtttttt taagtgaatg
     3901 aataattttt tgatattttt taatgcatga ggagcttcgg ctaaatttcc tgaatagtag
     3961 gaagaaacca gttgatcgtc cattgcatcc agctcttcaa ggaatgcggt gacttttgtt
     4021 gcatagaaag gaaaggcaat cgctggttct ccataaacaa ccgcgtgctc gcccatcaat
     4081 atgatctttc cgcttgattc tccttggcca tagtttgcca taatctaact ccttctcacg
     4141 taaaagtgat ttttaagcaa aaaataaagc gcccaaaacg agttgcgctg cttcacgaat
     4201 ttttttgtcc actaagggtc tcaaaaaaca ttcctccttt attttactaa aaccatctca
     4261 gaagtaaaac taagaatacg ttttctaaag aaaaaacact tttttcttaa gaattttttg
     4321 actttttttc ttctttgact agaaaaaaat acaattgaca ctactagata ttgggggtat
     4381 atttaaaaag gttggagtta aacacaatat ttagtgatga agtgagctgg aggtaaatga
     4441 gcgtgatcgt tttagcaggt acaattggtg ccggaaaatc aagtttaaca gaaatgatgg
     4501 ctgaacactt tgatagtcag gcattttatg aatcgattga tgataatgaa gtcttgccct
     4561 tattttatgc aaaccctgaa cagtatgctt ttttgctgca aatttatttt ttgaataaac
     4621 gttttgcaag catcaaacaa gcaatgaaag atgacaataa tgtattggac cgttcgattt
     4681 atgaagattc actgcttttc catctaaatg cagatctagg aagagcaaca gaaacagaag
     4741 ttcgtgtgta tgatgaactg ctggaaaaca tgatggaaga acttccctat gctgcccata
     4801 aaaaacatcc ggatttatta gttcatattc gtgtatcttt tgatacgatg ttggagcgta
     4861 tcgaaaaacg tggtcgttcg tatgaacaat tgtcctttga tccaagtcta tacgattatt
     4921 acaaagaatt gaacagacgt tacgatcaat ggtatgaaga atacaaagaa agtccaaaaa
     4981 tccaaatcga tggagaccgc tataattttg tggaagatcc tcaagcaaaa gaagaagtct
     5041 tgaaaatgat cgaagaaaaa ttagcagaga ttcgccaaac caaagtagcc atttgattta
     5101 cagttgctca aataaagggt aaacctttat ttgagcgact tttttcttta tactggaaac
     5161 aaatgtcagg aggatagagt atgcgggaaa aacactattt taatcaagac cgtaattttt
     5221 ggatcaatgt acagcaaaac gatgtgctag ctgttaaaaa cttaaaagaa gaatatggca
     5281 ttagtgacga gatgctgact tattctctag ataaaaatga acgggcgcgc gtagagtacg
     5341 attcttttga tgaagcgtta ctgcttgtat caaatgttcc gcaccagcaa aaagtcgata
     5401 atcattatga aactagtcct atcgctttta ttttaaaaga agacggtttg tttacattta
     5461 ccacgccgaa taccgagtac gtgattcgac taattcgatc gcttttggaa cgaatgccag
     5521 acatgagtgt atacagttta ttgtttcgta cattgttttt gatttctgat tccttttttc
     5581 ctttaatcga ggaagtgaat agtgaacgtc agcggcttaa tctgaaatta agagaaaaaa
     5641 caacgaacaa gaatctgctg caactttcag atttagagat cggtttggtt tacttagtta
     5701 caggaacaaa acaaaatgta gtacttttag aacaaatcaa ggcattggct atttatcgca
     5761 agttgtcaga aaaggaaaaa gaagagttgg acgatgcgct gatcgaagca cgacaagcag
     5821 ttgaaatgac gaacttagct tcgcagattt tagaccagct ctctggcact tataataatt
     5881 tgctgaataa caacttgaat gacacgatga aatttttgac ggtctggtcg ctgatcttga
     5941 ccgttccaac tattgtgaca ggattcttcg gaatgaatct ccagttaccc tttacccatt
     6001 ccgttttcgg atggggaatc gccttgatca tcagtttggt cttatctatt tggatgctta
     6061 ttgcactgtg gcggcggatt cgttgatcta gtctttgatc tgcaaaccaa gggcttgggc
     6121 gatcacaagt gcttgctctt ggttgacgat tagtcccgcc aaagaatctt gagataaagc
     6181 gattgctgtg aagaaattag tcgtaaagtc taatcccttc agagaagttc gaaaccagtt
     6241 cgaaccggtc aactgattgt cagacaaaaa aaggtttttc caagtgacct cataaaattc
     6301 gctgtcttct aattgacaat gatcgaagga gacagctttc aagtttgtac tactaaagga
     6361 agccatcgaa gcaatacaat cagtgaaagt acagtctcga agataacttt cggcaaaatt
     6421 cgtacctgtt aatttacatt gatgaaacac gacttggtgg aaactgccac caatccactc
     6481 cagattggaa aaatcacatt tttcaaaaat gacattactg cattcaaaat gacgtaaaac
     6541 tgttttttgc atcgtaagtt tttggatatg actctctctt aataccatat ttttggcatc
     6601 gagatagctt tggtcacccc cgttgatcag aagaccagag aagatctcct catcttctaa
     6661 ataaaactct ccctttgtaa gaagaggaag agaaggtgga ataggttcga tttttttcat
     6721 gtgggttcac ctcgtttttc tttagtatag caaagaagcg ggaatcactg ctagaaagtc
     6781 tgctaatcta atcattttca gaaaaggaag acaaactgta tgaaaaacat tgacaaaaag
     6841 attagttttt gctatactat gatggttgag aaataaaagc agaagcaccc gcttctcgcc
     6901 ttagttgata atgtcactgg gctagatagt tttcactggt tctattaggt gaagtacgcg
     6961 cgggttctgt aagagaactc gtttttttat tgccgtttat tcggtaagct tttctttctc
     7021 tcataatatt tggaggtgaa tgaccatagc aaaggatatg atggttaacg acggcattcg
     7081 tgcacgagag ttacgattga tcggttcaga tggtgagcaa ttaggagtta agacaaaagc
     7141 agaagcattg aatattgcag aacaagcaaa cttggatctt gtgttagttg cccctggtgc
     7201 gaaaccacca gttgcgcgaa tcatggacta cggtaaatac cgtttcgaac aacaaaagaa
     7261 agaccgcgaa gcgcgtaaaa aacaaaaagt gatcaatgta aaagaagttc gcttaagtcc
     7321 tacgatcgac ttgaatgact tcaatacaaa acttcgtaat gcacgtaagt tcttggaaaa
     7381 gggcgataaa gtgaaagctt ctatccgttt caaaggccgt gccattaccc ataaagaaat
     7441 tggtcaaaaa gtcttgaatc gcttagctga agaaactgcg gatattgcaa cagtggaaca
     7501 aaaagcgaaa atggacggac gcagcatgtt cttgacgctg gcaccgaaaa acgacagtaa
     7561 gtaatttgaa tgactaactg gctgttggac agccgatagt cggataacga aagattttga
     7621 ggaggaaata tagtcatgcc aaaacaaaaa acacaccgcg gatcagcaaa acgtttcaaa
     7681 cgtactggta aaggcggatt gaaacgcttc cgcgcgttta caagtcaccg tttccacggc
     7741 aaaacaaaaa aacaacgccg tcaattgcgt aaagcaagca tggtttctag tggcgacttc
     7801 aaacgtattc gccaacaact agcaaaaatg aaataagaag tacaaataac agaatctgaa
     7861 gatttatttt tattaggagg aattatacat ggcacgtgtt aaaggtggaa cagtaactcg
     7921 taaacgtcgt aaaagagtgc taaaattagc aaaaggttac tacggttcaa aacacacttt
     7981 atttaaaaca gcaaaagaac aagtaatgaa ttcatacaac tacgcatatc gcgatcgtcg
     8041 tcaaaagaaa cgcgacttcc gtaaattgtg gattgctcgt atcaacgcag cagctcgtat
     8101 gaatggcttg agctactcaa aattaatgca cggtttgaaa gttgctgaaa tcgacatcaa
     8161 ccgtaaaatg ttagctgact tggctgttaa cgatgcagca gcatttactg cattggctga
     8221 ccaagcaaaa gaagctttgg ctaaataagc taaacaatta taaagaggaa agaagataac
     8281 gaaaagttat gttctttcct ctttttttat ttacaatcct ccatcaaatg aaacaggaca
     8341 ataacgtata agtctaaaat agcataatta aggtttttta attgaaaact gaacatttat
     8401 ggtcaccctt taatgaaagc gctaactaca taagttagaa tgagtttgac tgatatatta
     8461 gtttgcttat cagaaaaaca aaatggacgg aggaataaca tgagtgatat tattattggt
     8521 attttgttag ttatctcatt ctttttcatg gtctggtact gtgtaaaagg ctacaacttg
     8581 atggtcggct ttgccatcat ggctactgta tggatgggat tagcgctagt cggaaacacg
     8641 ttttcaccaa acccggcgat ggaagggcaa ggagtaattg atgtgttgac gcatatctat
     8701 acgacggggc cagctgagta cgccaaatcg atcttggtaa atgtcttctt tggtgccttt
     8761 ttcgggcgtg ttctagtaga tagcggaatc gcagctaccc tgattcgaaa ggtagttgaa
     8821 cttggagggg acaagccaag aatcacgatg agcttactat gtattgtaac cgctgttata
     8881 ttcatgtcga tgacaggaat cggaccagtg atttctattg cagttattgt gttgccaatc
     8941 ttgatgtcat taggtatttc agtaccggtt gcactgttct catttatggg ctcgattatg
     9001 gctggaatct ttgctaatat cgtcaatttc aaacaatatc aaacgattta tgctggtttc
     9061 aatccagcgg ctgaaagcta tacttataat gactatttcc aaattggtat gattgggatg
     9121 attgtaagct tagttgtggt actaacggtc gctaatatat caatgaacaa aaagaaacgc
     9181 tatgcaatgg cagcaaacgt accagctgaa ggtggcgacg caccaatgat ctcatggtta
     9241 gccgtattat taccagtttt aggggtcgtt cttttagatc ttccaatcat cttaggtttt
     9301 attctagcag gtatctgggc attgctgttt actggaaaat tgcgcggagg ttataaagaa
     9361 atctgtcgtc agtttgcgaa attatttaca gatggcgcag tagatgttgc gccaatggtt
     9421 ggtttcttga tgaccttagc gatgttcaat aattcagctg cgtatgcttc tccttatttt
     9481 tcagctattt ttggagattg gataccgcaa tcaccattag tcttggcaat cgtatttgct
     9541 atattgacac cactaggatt tttccgcggt ccaatgaatc tagtcggttc aggctcagct
     9601 attttagctg tcgtattagc tgttaatcca acgatgtcgc cagccttttt gttcccgtta
     9661 tttgcaatca caacgattgc tcctcagcat ttagatatta cacaatcttg ggttgcttgg
     9721 ggattaggtt atacaaaagt aacttctcga gaatatatga agaaatccat cccaactggt
     9781 tggatcatcg gagcgatctt atgcctgatc acgttcttat tgtacgggaa cgcctagtaa
     9841 acaaaacgtc gataaaaacg attagatgaa tggaggaaaa gaaaatgaaa cgttttgtgc
     9901 gaatgggaat tgatgttggc ggtacacata cgaaagcagt cgcaatcgat aatgcgacgc
     9961 acgaaatcat cggaaaatct tcagtgaaaa caacccacga tgatgtccgt ggagtagccg
    10021 caggtgtcgt tcagtctttt caaaattgtt tgctggaaaa taatatcagt ccagaagatg
    10081 ttgtgtttgt tgcacattct accacacaag cgactaatgc actgattgaa ggagacgtag
    10141 caaaagtcgg cgtaatcggg atggcaaaag gtggattaga aggtttttta gcaaaacgac
    10201 aaactagatt gaacgatatc gatttaggga ataagaaaaa aatagagatt gtcaatgcat
    10261 tcttacctgt caaacactta aatgtagacc gtgtttcaga aacgatttct tctttagaaa
    10321 gagaaagagc ggaggtcttg gtttcttcta tggcatttgg agtagataat ggggaaccag
    10381 aacgagttgt ttatgaagca gcatcggtaa aatcgatccc tacaacgatg gcttctgaca
    10441 tcacaaaatt atatggattg acaagaagaa ctcggacagc agcaatcaat gcatctattt
    10501 taccaaaaat gctagatacg gcaacctcta cagaagattc cgtacgagaa gcaggggtca
    10561 atgtttcttt gatgattatg cgcggagacg gcggagtaat ggaaatcaat gaaatgaaaa
    10621 aacgacctgt tttaaccatg ctttccggtc cagcagcatc agtcatgggc tctttgatgt
    10681 acttgagagc gtctaatggt gtttattttg aagtaggcgg aacaacaacc aatatcgggg
    10741 tcattaaaaa tggacgtcca gcaatcgatt attcaattgt aggtggccac ccaacatata
    10801 tctcttcatt agatgttcgg gttctaggtg tggcaggcgg ttcgatggta cgggctaatc
    10861 agtcaggaat catcgatgtc ggtccacgtt ctgcacatat tgccggtcta gattatgcag
    10921 tatttacgga gacagaaaaa atcaaaggtc ctaaggttga atttttctct cctaaagaag
    10981 gagaccctgc tgattacgtc aaggtagtga tggaagacgg agaagaagtg actattacaa
    11041 atacatgtgc agccaatgtc cttggattag tgcaagaaga acatttttct tatggaaatg
    11101 tcccatctgc acgaaaagcc atccaagcat tagctgatta ttgtcatacg acggttgaag
    11161 acatcgcaga acagatcatg gaaaaatcct atgctaagat tgaaccggtg attttagaat
    11221 tggcagacaa gtatcacttg gagaaagatc agatttctct tgtaggtgta gggggcggcg
    11281 ctgcctcatt gattacttac tttagtaata aaatgggtgt gaaatattcg attcctgaaa
    11341 acgccgaagt gatttcttct attggtgtag cacttgcaat ggtccgagat gttgtagaac
    11401 gtatcatccc ttcgccaagt aaagaagata tacgatcgtt gaaaaatgaa gcgatgaata
    11461 aagcgattga atcaggcgct acaccagaat cgatcgaagt ccacgtagaa atcgatccac
    11521 agacttcaaa agtaacggct atcgctactg gttctacgga agtgaaagca accgatctaa
    11581 ccaaggagat cacaacagaa gaagcactag agcttgctgc agaggatatg cgattaaata
    11641 aaaatgaagt ttgcttattg gaaaatacac ctttctttta tgtatgcggc gaacagaatc
    11701 gttcaaaaaa tgctggaagt cttcggatca tcgatcaaaa aggatttatc aaggtccaac
    11761 gtggacatgc ttcatgtatg aaaacaactg cagccaatta tatgacagct gtcgaacaac
    11821 tttgggaaga tatggcagtt tatcaaactg aattgattgc ccgaccagaa ttttatctct
    11881 gcttaggagc aagagtctct gattttacag cgacggatct ggaacaacta cagcttttga
    11941 tggatctgga agtatctact atggaaccgg aggaagaagt gatcgtcgtt gccggaaata
    12001 tcaaacaaac ataagttaga agagttacta aacgaattac aacagatccc cgaagaaatt
    12061 tggggattct accagtttcg gcgagattta ttttggaaaa agattccttt gtccaagcag
    12121 aaaattctta tacaacaatc aatcgattgt ggtatcgaaa cggcatgtag catcaaaaaa
    12181 aagtaccctt ttgccgatgt aggagaaatt tgtgaacaaa tggctgttcc aatcgtttcc
    12241 tgtgaatcag agcaaataaa cgaacgaatc acttttgcaa cttatgcaga agatgaaggg
    12301 attcgattga tgacggagcc gttagaaaaa ttaaaatgtt caggactagc ttcgatctct
    12361 aaagaaacag cgcaagcttt gattattgga catgaactat ttcaccacat cgaagcttct
    12421 gttaagggaa tttatacgca aagcgaaaaa attgtgctgt ggcggttgcc tttttataca
    12481 catcaatcaa acattcgtgc attgagcgag atagcagcga tgagtttttc aaaagagatg
    12541 aatcaaagcg atttttcgcc ttatgtatta gaggcagtct tactttggcc atataatgaa
    12601 attcgtagcc aagggatctt agaagaaata aaaaaaatag aaaaaagatg tacggagtat
    12661 gatttagatt acaaataaag agactgtgac aaaagtcgtg tcacagtcct ttttttccga
    12721 ataaacggtg ttctcctgtc aactcctcgg tcacaagtca aaatattcaa caaacatgag
    12781 aagctgtttt ttgaaattgt tccttgtgac tcggagatga acggcaggct cacgacctct
    12841 tggaaaacgg tgttcaaaag cttgcatctg cggtaataag tccagccaag ttaaaaacat
    12901 aagaagctat ttttacttgg ctgttcttat tacttgatgc agggcagctt tttcacaacc
    12961 tctcaataaa cggtgtgcaa tcagctgacc ctcggtatta gctcaaaaaa aacggcaaaa
    13021 tatgaggaac tattttgccg tttctttctc taatactcag gtcaaaacgc tgattccaaa
    13081 acctcttatt tgatgggtct gtcctgaata tcttcaaaat aatcggggta attatgaatc
    13141 acgtattctt gctcctcgat aatcatatgt aaatgcatcg tgcaaagaaa tccgacttca
    13201 tcaaagttat gatcaatcat tgattgaagc attgtctgat gttcatctaa tactcgaccc
    13261 cagtctaatt ctgaaatcgt caaacgtaac catctgaaac ggttcaagtg cgtactataa
    13321 ctttctagcc aatcccaaat ttctcgtttt ccagcaattt cataacaagt tcggtgaaaa
    13381 tcagtatcca aatcaaaaaa agctttttta ttttgagcga ttactgcctg atcggtttgt
    13441 tctagtattt tttctagttt agcttgatct tgcttggtca ttttcgcact gcattcttgc
    13501 aggatcggtt tttccaactt ttcccgcgta taacgggcta atgaagcaga tcggatatcg
    13561 atttttgaaa cataagtgcc ggactgtgga atggttttta caagctcttg attgcgcagt
    13621 tggatcagtg cttctcgaat cggtgtacgc ccgatagcta gttgttcttc taacacttta
    13681 tcggagattt tacttccagg tgctaactcg gaataaatga tttgtttacg tatagattca
    13741 taagcttgct gttgcaaatt attgataacc atttaacctt cctttctatg cagatataat
    13801 ctattataac ataaatcgct tacaaatcgt gtgggcataa aaacacagtc tgcaaaaaaa
    13861 gccctgatag gcatgcctat tagagcctcg aaaagaaaaa tattgaatca atctggtcgt
    13921 acctcttgga tcggtttgac acgaccgccg attcttttag caaaagcttc ggattctttt
    13981 ttgtctttga aaatgagcag attgtctaag tttttttccc gagtgcgaca gccagtttta
    14041 tcgatgtaac cgtgcattac tttaacgaca tacatgggga tcacctgctt ttttcttttc
    14101 attatacgaa ctactcgaca caatacaaga aaaatgctta gacggtcttt attaagaatt
    14161 tacatcatcc aaagaagcgt acgcttggaa taactgatct aactccggat tgactttgct
    14221 cagcttcact aatcgttgcg aatcagaaag taaaaaacag tgtttactac tgccagtagt
    14281 ttttaatttt ttgtcttcag ttcccacaat ttcgtagcta aaatccaacc gtgtccccgt
    14341 atacttttgg atagttggat ggatgctcac tttttctccg taatggatca tttctttata
    14401 gctgcaattt acttccagaa cggggatgat gatcccagat tcttcgattt ttttataggg
    14461 aaaccctaga tgtaccaata aggctacccg agcctcttca aaccagcgga tataattgct
    14521 gtgatgaata atccccattt gatctgtttc ataataaaaa ggttctcgca cataacctgt
    14581 aaatttctcc atgactcatg cctcgttttc cattgatttt ttacaaaaat aattcatcca
    14641 tttcggaagt gcttcgctga tttgtgtcgg caaaacaata tattgttctt ttgccagctg
    14701 gtctccaatg aaactatgaa gataaatagc tgctgcaatc gtttggtcat tttgaggaaa
    14761 ctgggctaaa aatcctgtga tcatcccagc taaagtgtca cccatgccgc ccgttgccat
    14821 agcagcagaa cctaaaggat tggtgtagaa gtgctggtga ccataaattt ttgtctcatg
    14881 acttttcaaa acgagcacag caccgatttc ctgttgcttc tttttgtttt ctttatcccg
    14941 ttgttcttgt atcggtagag aactcaaccg ttgccactcc atttgatgag gtgtaagtac
    15001 agtttgttcg ggatagggta gcaaaagatg attagcagca agtaaactta aagcagagcc
    15061 atcaatcacc agccattgtt cttttgattg gttttctagt acttgtttga aacgttccaa
    15121 actcttagaa gaagtaccca atccgggacc aatcaagagt acatctgctt gctttattac
    15181 ggaaagaaac tggtcagtat ccgtccaaac tacaatcatt gcttctggca gatgactgtg
    15241 aagagcactc cgattttttt catcagttac tacagtcgtg agacccgctc cgctgtgtac
    15301 ggcagctaaa gcactcataa tgattgctcc gccatattgt tcattgccgc caatcaaaac
    15361 gatacgtcca aatgttcctt tatgtgaaat ttttggacga ggtgtgatga ctcttttcac
    15421 tagttgttcg tttatcagca tctaaaaacc tccttttact cattatagcg tatatttttt
    15481 ttagagaaaa acagataaga aaaggaattg tcagattttt tgaactattt ttttctgtaa
    15541 tttgtggtat catgaacacg aagacttaaa taagtggagg attaacttta tgacaattga
    15601 ttggcaaaaa gaagtagaag cacgtaaaga agacttgctt gaagacttga aaaatctttt
    15661 acgtgtcaac agcgagcgcg atgactcaaa agtaacacca gatgcaccat ttggacctgg
    15721 acctcgcgac gcattgaaac atatgttagc ttatggcgaa cgtgatggat ttaaagtaaa
    15781 aaatgtcgat aactatgcag ggcatattga tcttggcgaa ggagacgaaa cgctagggat
    15841 atttggacac atggatgtcg ttcctgcagg agatggctgg gacacagatc cttatgaacc
    15901 agtaatcaag gatggaaaga tctttgcacg cggatcaagc gatgacaaag gtccaagtat
    15961 ggcagcttac tatgcgatga agatcattaa agaacttgac ttgaaactat caaaaaaagt
    16021 tcgcttcgta gtcggcagcg atgaagaaag cggctggggc gatatggctt attatttcga
    16081 acatgaagaa gaaccagatt ttggtttctc accagatgct gaattcccaa tcatcaatgg
    16141 tgaaaaagga aatgtttctt tagctttacg cttcaaaggc gacaatgcag gagattatgt
    16201 cttgaaatct tttgtttccg gacttcgcga aaatatggtg ccaggaacag caactgcagc
    16261 acttcaagta ccaagtgcag atgcagctat cgcgatggaa gaagcatttt accaattcat
    16321 cgaagcaaat ccagtaagcg gaacgattga agcggacaat acgtatgtaa aaatcgaatt
    16381 agttggtaaa ggcgcacatg gtgcaagccc acaatctggt atcaatgcag gttctttctt
    16441 ggcattgttc ttagataact atgaattcct aggatctgct aaacaattta tccatgtagc
    16501 agctgcttat gtccatgaag atttttatgg agaaaaacta ggagtcgctt atgaagatga
    16561 aaaaatgggc aaattgacaa tgaatgctgg actatttgct tttgaagaaa atggtacaga
    16621 ggaagcgaac ttcatcaata tgaatttccg ttttccaaaa ggtgtaacag tagacggatt
    16681 gcaaagtgac atcgaacaaa cagtggggca agaaggcgca acagttactc gaggtgctcg
    16741 cgtaatggaa ccacattacg taccaatgga tgatccattg gtggctacat tattgcaagt
    16801 ctatgaagac cacactggag aaaaaggcta cgaacaaatc atcggtggcg gaacttacgg
    16861 acgtttgttg aaacgtggcg ttgcttatgg agcgatgttc ccaggatata ctgatacaat
    16921 gcatcaagca aacgaattta tgagtcttga tgacttgttc agagcaacag caatctatgc
    16981 agatgccatc tatcgtttgg cgaaataatt aattaaaaag aggatcaaga attgcaaatt
    17041 atttttgcag tcttgatcct ttttttactt tctactgtgg tattcatgat aaacatgata
    17101 tagattcaat tcatattctt tcttagcgtt cgtgacgact gtatccaaaa tcaaccctgt
    17161 tactaatgaa agaagtgcta aagtcatcaa tccagtactt aaaatcgcag aagggatgcg
    17221 tgtaataaag cttgtcagca tatattcgcg aatcacagga atccccgtga ccaatccaaa
    17281 taaaaagaag aagatggtcc aaatcccaaa gaaaagcaaa ggcttataat ctttaaacat
    17341 tttaataatc atcatgatca ctttgaatcc gtcagagaat gtattcaatt ttgattcgct
    17401 gccttcagga cgatcacgat aatcgattgg gatttcaacg aacttgaatt ttttatctaa
    17461 agcatggatc gtcaattccg tttcgatttg aaaaccagaa ctcataatag gaaaactttt
    17521 gacaaagata cgattgaatc ctcgatagcc ggtcatgaca tcaagaattt ttgttttata
    17581 cattctagta attgtatttc taacaaggtt atttccaaaa tcgtggaaag gtctcttatt
    17641 ctcatcaaag taggttccat ttgataggcg atcaccaatg accatatctg cttcaccaga
    17701 acgtaatttc tcgagcaaac catgtacagc ttctgcagga taagtatcat cgccatctac
    17761 cattaaataa tagtcggcat cgatatcaaa gaacatttgg cggatcacat ttccttttcc
    17821 ttgacgaggt tcttttttta cgattgctcc accttgaacg gccaattcgt atgttcgatc
    17881 ggtcgaatta ttatcataga cataaatatc tgcttctggt aattctcgtt taaagtctgc
    17941 aatgactgtt gaaattgttg cttcctcatt gtaacaagga atcagaacag caattttttc
    18001 ttgttgttcc atttttcact ctccttaact atagaaaaca aaagctaaat taaaaatacc
    18061 tcataatcaa aggaaatgct agtttttccc gctaaatatc atttatttaa aaagaaaata
    18121 ctggaatata tgtttggaaa gctctatcta aaaaaccacc cactacaaaa gaaggacatg
    18181 atacctctct tttgaatagt gggtgcgtat tcgttctctc acttttttga cgtattaatc
    18241 tgttgcacct ttttttcttg aaatttctaa tacggttcct gtatgagcat ctgctaaaaa
    18301 ttcataataa acagtttcgc catcttctat tcgagaaaga cctccccgat aagcactcga
    18361 ccgaacggcg aatttcctaa taggttcctt ttcaaaagag atccaagaac cttcgattgc
    18421 accttctttt agaaaagatg acttgatatt ttcaagtact tggtctgctg acaatacttt
    18481 tttgcgatga taccaaatcg ttgaagctac cccgctcaat aatcctagac cgattccaac
    18541 tgctaacccg cctttaaaat agcttagttc gctttcttca tacatgtgga catacctcct
    18601 tcttctcact tgttactcct tgtgcttatt ttaccacact ctcatatttt ctttgaaata
    18661 aataaccgct accagaaaaa ataagctata ataaatacga tcggtctgca gaaaaaatca
    18721 tattttatcc gcagatcaat ataagtctga gaggagttta gtctgaaatt tagacgaata
    18781 gcatatggaa gaaaaaacat ttcaacgaat caaagagtta acagaattac aaggaacaag
    18841 cggttttgaa caagatgttc gcgcttatat ggaaagtcat atggaaccgc tggtagatga
    18901 gttacagtta gatggtttgg gcggcatttt tggtctgcgc catcatgaag aagcggatgc
    18961 accccgtgta atggtcgcag cacatatgga tgaagtcgga ttcatgctga cacaaatcca
    19021 agaaaacggg ctttttaaag tcgtacctct aggcggctgg aatccttacg ttgtttctgc
    19081 tcagcgtttt acacttaaaa cctctactgg taagaattat ccatgtattt cttcttccgt
    19141 tcccccacat ttattgcgag gaacaagcgg acaaaaatca gtagaagtaa ccgatatttt
    19201 gttcgatgct gggtttgaat caagagaaga ggcaatgagt tacggtgtcc ttccaggaga
    19261 cacaatcgtt ccttacgctg aaacgatcaa aacagccaac ggaaagaata ttatcagtaa
    19321 atcatgggac aaccgctatg gctgtacaat ggtattagaa gctttagaag cgttgcaaaa
    19381 tgaaacatta ggtcatacat tgattgcagg cgcgaatgtc caggaagaag taggcttgcg
    19441 tggttctaaa gcttctgtca ataaattcaa gccagatctg ttctttgcag tagactgctc
    19501 tgcagcagat gatacagtga cgaaaaatgg cacattcgga catttaggag aaggtacatt
    19561 gatgcgtatc caagatccag gtttgatcat gcttcctcgt ttgcgcgagt acttgctgga
    19621 tatcgctgaa acaaacaata tcccttatca atactttgtt tcaaaaggcg gtacagatgc
    19681 aggtgctgct catacacaaa acgaaggaat cccaagtaca gtgattggcg tagtgggacg
    19741 ttatatccat acgcatcaaa cgatgttcag tattcgcgat tttgaagctg cacgagaaat
    19801 gttgattcaa acactgaaag gtttggataa atcaacagta aatacgatcg tatacggaaa
    19861 ataatgcgat agtgaaacta taaaatctgg caaaagattg ctttttgcca gatttttttt
    19921 ataaaaagag gatcaatgtt tgttagttcg aaagaaaggt gtataattta attgaaaaat
    19981 acataaacag aaagtagagg acaaagaatg attatcccaa atagtttaga agaattagca
    20041 ggctacgtag aaactggaaa gagtgtattt ttctttactg ccggctggtg cggagactgc
    20101 cgttttatca aaccgcaaat gcctgaaatt gaaaatgact tttctgattg gcaatttatt
    20161 gaagtagacc gtgacaagta catagatgta gccgctgaat ggaacatttt tggtatccca
    20221 agttttgtcg tgatccaaga cggaaaagaa ttaggtcgtc tagtgaataa agatcgtaaa
    20281 acaaaacagg aaatcgaatc gttcctagaa agtgtaacaa aaggctgaca tctgttagga
    20341 ggggtcaaga tgaatcaaga atataagaat attttagtag gtatcgacgg tagtgaacaa
    20401 gcacttgctg ctttcaaaaa agcggtagaa gtggctcgcc gtaataatgg gaaagtatat
    20461 gtagcaaacg taatcgatca gcaattttat aactttatgg gctatgcacc tattgatcaa
    20521 aatctagtcg atcagcaaac tgaaacagcc aaggaaatga tcgaagaatg taaagaatat
    20581 gggaaatctg ttgattacac aaatatagaa ggaattattg catatggttc tgttcgtgaa
    20641 tccatggcag tcaaattgcc aaaaaaatat gagatcgatc taatcatggt tgggcagtca
    20701 ggtctaaatg cagtcgaacg ctttatgaca ggaagtgtag ccagctacgt gatacgtcat
    20761 tcaccttgtg atgtcttgat cgtttctgac gaagaagaac agccaagtaa ttaagcaagt
    20821 ggaacttgta cgaccttttt aatcaattaa ctaaaacagt aaagggactg tgacaaaagt
    20881 cttgtcacag tcccttgtta cgaataaatg gtgttccaga agaggcttct tcggaaataa
    20941 agcatgaaaa aaatttcatg cagtgaatgc aattttttgt taagataaat ctcagcaaag
    21001 gataatggag gaaagaacat gatttttgct tataacaaag cacacgtcgg agacaccttg
    21061 atggttatta tagccgacga taaaggaaca gaaaacactg ttgaacgcaa atggaatgtt
    21121 gctcggatca aagatgaaca aggtcaagtt gttgcttgga actttttcca tatctccgat
    21181 catctaacaa tcgaagggaa cggccaagta agcttaacag atgaggaatt agcgaaattg
    21241 aatcgattga tcaaagaagc aggattcgaa gaacagcttg aagctgatca tgaaccgaag
    21301 atcgttgtcg ggtacgtaaa aacatgcgtc ccacatcctg attctgacca tttatcgatt
    21361 actgagacag aagtagacaa tggtacagta ttgcaaatcg tttgcggtgc acccaatatc
    21421 gaagctggac aaaaagttgt cgttgcaaaa ccaggagcta tgatgccaga tggaatgatg
    21481 atctggccag gaactttgcg aggggtagat agctatggaa tgatctgttc cgctcgtgaa
    21541 ttgcatttgc caaatgctcc agcaaaaaaa ggaatcttag tattgcctga ggatgccgta
    21601 gtcggagaag catttccaaa ataaagaggt tgtgacaagt ctttgtcaca acctcttttt
    21661 tattaatttt cactattttg attttgtttt aatgccgatt gatcgatcgt caattcaaca
    21721 gtagttgttt tttctttcga gccttcatag taagtgattt tgacagaatc tcccactttt
    21781 ttcttataca aagcagattg aagttctaca ccagaagaaa cttctttgtc atcgatctta
    21841 gtaatgacgt cgtattgttt caatccagct ttttcagccg gtgtagctgt ttggacattt
    21901 gtcacgatga caccgttagt tacagatgaa ggaatcttca agatttgttc ttgttgctga
    21961 gtagaaacgg cagataagtc gaccattgtg atacctagag ctggacgtgt cacttttccg
    22021 tctttttcca gttgattgat gatattcact acatcgttac ttggaatagc aaatcccatt
    22081 ccttctacgc ttacattaga agtagattca gaagtacttg cgatcttact tgagttgata
    22141 ccgataactt gtccttcgat attaactaaa ggaccaccag aatttccagg gttgattgct
    22201 gcatctgttt ggatcgcatt gatattgact gtttcgttcg attcattcgt acttgtcact
    22261 tgtcggttca aggaagaaat gattcctgaa gtgacagaat ttgcatattc agatcctagt
    22321 ggggaaccaa tcgcaatcgc aggctcacca accttcagag cacttgagtc accaaaagag
    22381 gcaactgttt cgactttgtc tgaattgatc ttcaacaccg ctaaatctga ataagcatct
    22441 gttccaacta attcagcttt taccttcgta ccgtctttca tcaagacttc aagaccttgc
    22501 tggccatcta ctacgtgatt attcgtgact acataagcag tattcccgtc ttttttgtag
    22561 atcacgccgc ttccttcact ataagcttcc aaattactat catctgagct gctactttct
    22621 tcttgctgcc cgaatagtcc gccaaaaccg cttgattggt tttgactttg taagttgata
    22681 acagaaacga cagcgtcttg aactttatct accgctttgg tgatatcaga atctacattg
    22741 actttgacat tttccacaac tgtttcaccg gcagaattct gattgccgct tgtagcagta
    22801 gaactattgt tgccagtgcc catcgctgca taaaaaatgc cagctgtcag tagtcctcca
    22861 acgatccctc caacaagccc cagacctaac ttacgccaga ggctattatt tttacttttt
    22921 ttcatctttg gtgtcacatt ttttctatcc atgtgttcct cctccaatta cattcattta
    22981 tctactgtta gtatagtctt atttgttgac tttagtctac tttgagactg tgaacttttt
    23041 atgaaaaact ttaggaaaaa tcattgtttt cagatgaaaa tatttgattt tctttttcca
    23101 cagatactgt gtaaaactac gcggatagga ttggaaaaat aagggataaa acatatccac
    23161 agcctgtgta taaagtggat aaattcttat aaaacgtatg tttgcctaat gaatgtgatg
    23221 aaataaggta aaataacact gttttctgtg gataaacctg tggatgttgt gcataactgt
    23281 tggggaaatc tttttaacaa aaatagccaa aataaacata tagacgaaaa aattgattat
    23341 aataaacaaa gtgagcatga agaccaaagg agagaaaaca tgaatatcaa aattatctca
    23401 gtaggaaaat taaaagaaaa atacctgatc caaggtatca atgagtatgt caaacggctg
    23461 aatgcctatg caaaaatcga attgatcgaa gttcctgacg aaaaagcccc ggagaattta
    23521 agcgaagcgc aaatgagaca agtaaaagaa aaagaagggg aacggatctt agcgaaaatc
    23581 aaagaacaag aatacgtcta tgccttagca attgaaggga aaaatcctac aagtgaatct
    23641 tttgctaaac aaatcgacca attaggtatc caaggaaaaa gccaccttgt ttttgttatc
    23701 ggcggctctt taggactcag cgaagccgtc atgaaaagaa gcaatgctca gatctctttt
    23761 ggaaaaatga cgtatccaca tcaattgatg cgtctgatcc ttgtcgagca aatctaccgt
    23821 gccttccgga tcaatgcggg ggctccatac cacaaataat gatatttttt aagagaaaaa
    23881 attatcccta ttttaaataa tagcaatagg tagtggtagg gagaaattta taaataactt
    23941 ttttatttgc tttggtagcc aagtaagttg caaaagaaaa atagatactg ttaaaaagat
    24001 aatgtagaca tagaaacaaa tacgtaaaat tttagttaga ataatggcaa ggagaaaaaa
    24061 catgatagat gaaaaaaagt gtttaaaaaa tctattagag gatatggatg atattgaaga
    24121 aaactatcta aatggactgg gaaaacaaat atatttcaga tacttaagct atctaaaaat
    24181 gaaataagac atagtaattt tttagctttt ttgtttgctc caaatgaaac ccacaattta
    24241 tctgatgagt tttttaaaat gtttttgaaa aggtatatag attctaatga tgataccaaa
    24301 gctgctatca attattttga tgctttactt aatagctatg aagatttaat tgtttacaga
    24361 gaaaataaga atattgatat tttattggta tcggaaaaaa ataaaatagt ggtgtgcatc
    24421 gaaaataaaa ttctgtcttc ggagtctgga gggcaactta ataaatacca aatatatata
    24481 gaacgcaatt attctaacta taaaaaaatt tttgtttttt taactccaga tggaaatgaa
    24541 cccacaaatc ctagttgggg cataattact tacaagaata tcgttgaaga gagtgtaaaa
    24601 tattttgtgt aaatagaaaa aaggaagtcc cttctgtaga atagagttac cacaacacat
    24661 tcacagaaaa gaggacttcc atatgaacga ttttactaca gaaattatgg aaatactaat
    24721 caataaaggt gatttggatg atttgtttcg tcgtcaccta gaattggcta ttaacgcttt
    24781 attacaagct gaattaacgg tatttcttga ctatgaaaag tatgatagag ctggatttaa
    24841 ttcaggtaat tcccgtaatg ggaattattc gcgctctttt aaaacagagt acggtgaatt
    24901 gaatttagta atacctagag ataggaatgg agacttttct caacaaactt tacctgctta
    24961 taaaagaacc aatgactctt tagaaaccac tattattcag ctagttcaaa aaggaattac
    25021 tatgtccgaa atctctgatc taatcgaaaa aatgtatggt cattattaca aaccacaaac
    25081 tatttcaaat atgagtaaaa ttgtgtctga agatgtttcg gcatttaaag aaagaacttt
    25141 agaagctaaa tactcagtca tttttatgga tgctactcat attcccttaa aaagacaaac
    25201 cgtatcaaaa gaagctgtct atatagtaat tggtatcagg ttggatggaa ctaaagaggt
    25261 tctaggattt actatagctc caactgaatc tgcttatgtt tggaaagaga ttcttcaaga
    25321 tctaaaagac cgtggtttag aagaggtttt gttagtcgta acagatggtt taagtggtat
    25381 tgacgatagt attcatagtg tttatccaaa tgctcaattt caacaatgtt gtgtccatat
    25441 atctagaaat atcgctcata aggttcgtgt tagtgatcga caagaaatct gtagcgattt
    25501 caaattagtt taccaagcaa gttcaaaaga agaagcaaat aatcaaataa ggtttatgat
    25561 agataaatgg aaaaagcagt atccacgagt ggttaaattg ctcatgaatc ctgctatatt
    25621 aaccttttat aatttccctc cgtcaatcag aagaactatt tattcaacta atttgattga
    25681 aggttttaac aaacaattaa agaaatatac caaaagaaaa gagcaatttc ctaatgaaga
    25741 atctctggag agatttctag tatctcaatt caacaactat aatcaaaagt ttctatgccg
    25801 agttcataaa ggttttaaag aaatacatga tacattagaa tcaatgtttt aacttgatca
    25861 acagaatggg cttttccatt tacacataat tattgacaca acctattctg gaaacttaca
    25921 aataaaagct tattcttcag ccaccttcgg gtggttattt tttataaaaa aatgtaaaaa
    25981 aatattgata cataaataaa ttagttgtag taaatagttt tagaattgaa tttctctatc
    26041 ctttttaaat aattttttag acaaaaaaca gaaagtgtct aaagaaagct tgacgaagaa
    26101 aataattttt aataacttat ttaaggaaat tttttgaagg agaagataaa agtgagaaaa
    26161 aagattatta ttaatgctgg agtaattata ggattgatgt tagtaatttt ctccggaaag
    26221 caatatgctg ataatatttt attatgggga ggggaagata atattgaaaa gatcaacaac
    26281 aatttaacta tattagacac agctctagaa aataaagagc aaaaaattag tattttaaat
    26341 tcacaattgt cttcaaacaa ccaaactctt gaacaactaa gaactaatat tgaagtttcc
    26401 aaacaaaaag tggcatcttt agaaaacgac aagaatcaat tagtatcaga gaaaactaat
    26461 ttagaaaatc aattgtcagc aaaagactct gaattgcaag gaaaacaaaa tgaaattaat
    26521 gcgaaaatag acgaaattaa ccaaaaagta gctgaaataa atcgattaaa tagcgattgg
    26581 aataatcgtt tacaaaatga aaagaacaaa tttaatgaag aacaatctac tattaatagt
    26641 ttaaaccagc aaattaatca aatgttgagt gaaaaaaata acattcaaaa tcaactgcaa
    26701 gctactcagc aaaagctaga agaagaaaag tcaaaaaata gtagtttgaa taattacatt
    26761 gaaaagcttc aaaaagctaa aaatgatgta gaggataccg caaataaagc acaacaaatt
    26821 gtaaatgaac atacaatcca atagatatag ttttaattta acaaatggta tgtttggaga
    26881 taatgagata gaatataaat gtcataatat tatacaatct aaacaccgtt tccttttcta
    26941 tttttgatga catcagtata tagctactcg aaagagtagt ctttttatta ttctcgctta
    27001 ttattgatat gaaaatttcg atttgacaaa aggtaccgaa taattttgta atatgaatta
    27061 ttatcaagaa gtaattatga tgataacata tggaaactag ttagtaataa taacaggtga
    27121 ttaaactttt gaacgacttg taattctata ttttttcttt taagtaaaaa atataggtga
    27181 ttttttttga cttcatattt ataataaaga cacgtaaatc aattattttt cattttactt
    27241 taactaataa tgtttatttg gagggattat tatgttagat gatagattga cgtgttctaa
    27301 ttgtggtaca ttattttact atgaggaagt tagaaatatt gtaaaacata gaaaaaaaga
    27361 aatgcctata cgttgtccaa attgcaatga agttattaag cgaaagttgt ctcatggtta
    27421 ttttgtcagc tacgaactat atgaagaaag taaaataaat ctgaaaaaaa aaccaaaata
    27481 ctataaaaat ttgaaaactg gagctattat aactgaaaaa gaatttaaaa atttagtgac
    27541 tgaagaagaa agcaggtttt ataatttgtc tggtaatatt tgccctggat ttatggatca
    27601 gattattgaa aatgagtcaa ttgaatcaat tgaaaactat gttcctgttg acttaccaaa
    27661 atagaaaaaa taatcctgtt tttacagtga attattttaa ttttgatttt caataaaaat
    27721 atattacaat aataatcgta atagctaatg aaacaatttc tcaatctttt taccactcca
    27781 aacagggagc gtcaataatt ttgtgtaaat aactcgtcct tctgcaaaat aatgggttac
    27841 tcagtaaaca ttgaagctaa tgtatccgtc acttgttgga agcctttatg gcttctattt
    27901 aagaattttt gattgtatgt atcaaagatg gatactagga aacgctctag tgattcttca
    27961 ttttgaaact gctcttttct gcggctgtat ttcttgattt gtttattgaa agattcgatt
    28021 gtagaaccag aaggaatgga gaacactttt gaactttaca acaaaactac tgttgataaa
    28081 ttaattccaa ttttagttcc aactgattta aatggtcatg atgttttact tcgttttaac
    28141 ggatttttag gtgaggatta tagataccta aaaatttctg atcctcaacc tttaacagaa
    28201 taataaaaaa cgtgtaatca attatttgat tacacgtttt ttatttcaat cttcgttgta
    28261 gtagtggttg cgacataccg aaaggtaatc ttcattacct cctactacaa tctgttcacc
    28321 tgaataaact ggaataccat caacaatacg agcattcatt acagcctttt tattgcaaaa
    28381 atggcaaata gttttaattt cctcaatttt atcagcaaat gtcaataatg cttcggatcc
    28441 cttgaagaga ttattttgaa aatcattctt caatccatag caaattactg gtacttcctc
    28501 attcattacg ataagtgata gatcaataat attctctcta cttaaaaatt gagactcatc
    28561 gaccaaaata caatcaactt ttccgtactg atcaataatc tccactaatt ctccgtacac
    28621 atccatttca gaagtaattg caatagctgg tttcgaaaca cctatacgac tctcaacttt
    28681 tccaaatcct gatcgagtat ctattgcgct tgtcattatg ataactctct tcccttgttc
    28741 ttcataatta tgagccactt tcagtagctc aatactcttt ccactattca ttgttccata
    28801 tctgtaaaat aattgtgcca ttaaatttat tcccttcttt tacaattcaa ttattcctta
    28861 attccatctg cttttatgca gctgctcgtt tattccttga tatgtctata acatctacta
    28921 tccctaaaac caatttataa gccattagag atggtattcc tgaacatctc tcatattgtt
    28981 ttttgagtgg tatatcatct gaaaaactga aggaa
//
LOCUS       DACGMI010000037        27464 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.038, whole genome shotgun sequence.
ACCESSION   DACGMI010000037 DACGMI010000000
VERSION     DACGMI010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.038"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(115..918)
                     /locus_tag="IXT46_001796"
     CDS             complement(115..918)
                     /locus_tag="IXT46_001796"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAQ4947706.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(938..1780)
                     /gene="kduI"
                     /locus_tag="IXT46_001797"
     CDS             complement(938..1780)
                     /gene="kduI"
                     /locus_tag="IXT46_001797"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAQ4947707.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(1796..2803)
                     /locus_tag="IXT46_001798"
     CDS             complement(1796..2803)
                     /locus_tag="IXT46_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAQ4947708.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(2810..3454)
                     /locus_tag="IXT46_001799"
     CDS             complement(2810..3454)
                     /locus_tag="IXT46_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAQ4947709.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(3554..4312)
                     /locus_tag="IXT46_001800"
     CDS             complement(3554..4312)
                     /locus_tag="IXT46_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAQ4947710.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(4439..5590)
                     /gene="fucO"
                     /locus_tag="IXT46_001801"
     CDS             complement(4439..5590)
                     /gene="fucO"
                     /locus_tag="IXT46_001801"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAQ4947711.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(5672..5983)
                     /gene="rhaM"
                     /locus_tag="IXT46_001802"
     CDS             complement(5672..5983)
                     /gene="rhaM"
                     /locus_tag="IXT46_001802"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAQ4947712.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(5985..6830)
                     /gene="rhaD"
                     /locus_tag="IXT46_001803"
     CDS             complement(5985..6830)
                     /gene="rhaD"
                     /locus_tag="IXT46_001803"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAQ4947713.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(6844..8100)
                     /gene="rhaA"
                     /locus_tag="IXT46_001804"
     CDS             complement(6844..8100)
                     /gene="rhaA"
                     /locus_tag="IXT46_001804"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAQ4947714.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(8097..9557)
                     /gene="rhaB"
                     /locus_tag="IXT46_001805"
     CDS             complement(8097..9557)
                     /gene="rhaB"
                     /locus_tag="IXT46_001805"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAQ4947715.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            9710..10579
                     /locus_tag="IXT46_001806"
     CDS             9710..10579
                     /locus_tag="IXT46_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4947716.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(10705..11604)
                     /locus_tag="IXT46_001807"
     CDS             complement(10705..11604)
                     /locus_tag="IXT46_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4947717.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(11769..12593)
                     /locus_tag="IXT46_001808"
     CDS             complement(11769..12593)
                     /locus_tag="IXT46_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4947718.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(12604..13899)
                     /locus_tag="IXT46_001809"
     CDS             complement(12604..13899)
                     /locus_tag="IXT46_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HAQ4947719.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(13915..14394)
                     /locus_tag="IXT46_001810"
     CDS             complement(13915..14394)
                     /locus_tag="IXT46_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAQ4947720.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(14400..15428)
                     /locus_tag="IXT46_001811"
     CDS             complement(14400..15428)
                     /locus_tag="IXT46_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HAQ4947721.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(15445..16551)
                     /locus_tag="IXT46_001812"
     CDS             complement(15445..16551)
                     /locus_tag="IXT46_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAQ4947722.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(16780..19377)
                     /gene="adhE"
                     /locus_tag="IXT46_001813"
                     /gene_synonym="adhC"
     CDS             complement(16780..19377)
                     /gene="adhE"
                     /locus_tag="IXT46_001813"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAQ4947723.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(19682..20062)
                     /gene="yajC"
                     /locus_tag="IXT46_001814"
     CDS             complement(19682..20062)
                     /gene="yajC"
                     /locus_tag="IXT46_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAQ4947724.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(20159..21304)
                     /gene="tgt"
                     /locus_tag="IXT46_001815"
     CDS             complement(20159..21304)
                     /gene="tgt"
                     /locus_tag="IXT46_001815"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAQ4947725.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            21522..22220
                     /locus_tag="IXT46_001816"
     CDS             21522..22220
                     /locus_tag="IXT46_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAQ4947726.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(22388..25027)
                     /locus_tag="IXT46_001817"
     CDS             complement(22388..25027)
                     /locus_tag="IXT46_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4947727.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(25646..26677)
                     /gene="queA"
                     /locus_tag="IXT46_001818"
     CDS             complement(25646..26677)
                     /gene="queA"
                     /locus_tag="IXT46_001818"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAQ4947728.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            26870..>27464
                     /locus_tag="IXT46_001819"
     CDS             26870..>27464
                     /locus_tag="IXT46_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4947729.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDE"
BASE COUNT         7619 a         6115 c         4844 g         8886 t
ORIGIN      
        1 gcttctgtcc cagcctcttt tttcgaataa atgatgttta atcagctgtc cttcggtatt
       61 cgttcaatcc gctgatttca caacctctcc actaaacagt gtactaaagc tcttttaagg
      121 ttgttttccg atataggcaa gtatgcctcc gtccacatac aagacatggc cgttaacgaa
      181 atcagatgcg ctagaagcca agaagacaga tggtccagcc aaatcgattg gctcgcccca
      241 gcgtgctgct ggcgtacgtc caacgataaa ttgatcgaat ggatgacgtt caccgttttc
      301 ttgtgtttcg cgtaatggag cagtttgcgg tgtagcaata taacctggtc caattccatt
      361 acattggata ttgtattgac cgtattcaga agcgatgttt ttcgtcagca tttttaatcc
      421 gccttttgcc gcagcataag cactgaccgt ttcgcgtcct aattcactca tcatggagca
      481 gatattgatg attttaccgc cgcctttttc gatcatatcc ggaataactg cttttgaaac
      541 gatgaatggg gcatttaaat ccacgtcgat tacttggcgg aagtctgccg catccatttc
      601 gatcatcggt gtccgtttga tgatccctgc attgttgact agaatatcaa ctgaacctac
      661 atcttctttg atctgttgaa ccatcgcttg aaccgcttct tcatcggtca catcgcagac
      721 ataacctttt gcatcgatgc ctgcttcttt ataatgcgct ataccttcat caactgattc
      781 ttgattcaag ttattaaata cgatttttgc tcctgctgta gctaaagagc gtgcaatctc
      841 aaatccaata ccatagacag caccggtgac taatgctact tttccatcta aacgaaacat
      901 atccatacta aattccatca ttttctctcc cttatgctta ttttaattga tccatttgca
      961 ccatatccat gtctgtatag gtgatatttt ctccgcacat tgcccagatg aatgagtaat
     1021 tgcttgtacc tacacctgaa tggatcgacc agcttggcga aataatggct tgttcattgt
     1081 ctacaactaa atgttttgtt tcatctggtt tgcccatcat gtggaacaca cgtgtatctt
     1141 cattggcata atcaaagtag acataagctt ccatacgacg ttcatgtgta tgacaaggca
     1201 tcgtattcca agcgcttcct ggttctaaaa tcgtataacc catttgtaat tgacagcttt
     1261 cgcatacatt tggatggatg tattggtaga ttttacgttc attcagtgtc aggccttcac
     1321 cagtctccat tggttttact tggtcgatac tgatttttac atttggatat ttatgatgag
     1381 ctggaacaga actaatatag aatttagctg ggttttcagc atcttgagaa gaaaatacaa
     1441 catgtcgtgt ttcttttccg atatagtatc cgtcttgttt tttcatttct tctttttgcc
     1501 catcgatctc gatgaatcct ggtccaccga tattgatcac acctagttca cgacgctcta
     1561 agaagtaatc aacacctagt tctttgtcta atgtgatttc taattctttt tcagtaggtg
     1621 tcactccacc aaagatcatt cgatcgttgt gcgtataagt caaactgatt ttccctggtt
     1681 caaatacctt ttctactaaa aattcttttc tcaattgttc cgttgaataa tgacggatat
     1741 cttctggact gtgtgtataa cgtgtttcca tttcttgcat tttcttctac tccttctatc
     1801 gaatgatttt tccagagccg catgctaaaa attgtgcgac ttcttcttga ctaaattggt
     1861 tgcagtcccc atggatcgta tgcttcaagg cagaagctgc cgtagcaaaa tcaatgattt
     1921 cttgcggaga catattggat aaaatcccat ggagcacgcc acctgcaaaa gcatctccgc
     1981 cacctactcg atccacgatt ggggtgattc tatggacttg ggattccaca tattcatggt
     2041 tcatccacaa tgtccccttc aattcatttt cacttgctga atgaacggta cgcttggtcg
     2101 aataaaacac ctgaatattc gggaactttt cctgcatttt ttgataataa taaattagag
     2161 gttgttcttc tgcttctggc gctttctcga tacctaacaa ataaagagca tccatttttc
     2221 cagctgagca gatatctact aaaggtaaaa gctgatggat tacttcgctg gcttcttgct
     2281 gtgtccataa ttttccacga tagttgatat cgaagctgat caggcagcca gctttttttg
     2341 cagcttctat cacctgtttc gtcatttttt gccatttttt agacaaagct ggggtgattc
     2401 ctgaaacatg aaatatatct attccttgga ataactcctc tagcgaccat tccaaatgat
     2461 ccatttcagc aaaacttgat ccggcacgat catagatcac tgaggcggcg cgttcgccac
     2521 taccagtttc catataataa gtacctagtc ttgatccacc agataatacc tgtttcgtat
     2581 ctactccata acattgcaag tgctttttga ctgcttttcc caatgcgtta tcaggtactt
     2641 ttgtagcaaa aatcgcttca tgtccgtaat tagctaaaga aattgctacg tttgcttccc
     2701 ctccgccata atgggcagcg aatcgttcac ttgaatcgat acgggttccc tgctctgtgg
     2761 acaatcgcaa catgatttct ccgagtgtca ctacttttcc cataagcagc tacctcttga
     2821 tttctttcat ttttgctgca tactgttgcg cgacttccgt tactttgtca aaatctcctg
     2881 tagctgcggg tgctaaaagg ttcccaccta ctccgactgt tacgacacca gcatcgaacc
     2941 actctttcat attgtccaga ctcacaccgc cagttggcat gatattgact tgaggcatcg
     3001 gcgccttgaa ggcagaaatg atacttggtc cataagcgct tccaggaaat agtttgacga
     3061 tatctacccc gcttttcagc gctgttttga tctcggtaat agtcatacat cctggtaagt
     3121 aaggaatttg atacagattg cacatctctg ccgtttcttg atcaaaggaa gggctaacaa
     3181 tatactctgc gccagctaag atagccaagc gagctgtgac agcgtctaat actgtgcctg
     3241 cgccaatcac tatttctggt tggtctttgt agaatgacaa aagttctttg attacttgat
     3301 ctgcttgagg gactgtaaaa gtcaactcaa taccagttag accacctttg atgattgcgt
     3361 ggcaagcatt caaagcttct tctttgcttt ttccgcgtac caccgcaatc actccggcgt
     3421 ttttcaatcg agataaaata tcaatttttt tcatcttctc cacctatttc ctatttagaa
     3481 attttatttt ataacttgga aatctatacc catattatac ggcagaaaag aaaaattgca
     3541 aacgcttttt tcattatttt tgaattcttt gctcgatttc gctttttgtt tgcttgaggg
     3601 cactgattat ttgttctttt gtctcatctg ttaaacgata tttcggcata cttacactaa
     3661 atgcaccaat gatttgttcg tttttcacga ttgaggctcc tatacaaaaa atatcacgtt
     3721 cgatttcttc atcgtcaaat gcgatgtggg tttcttttac cgttttgatt tcctttttca
     3781 accgtaatgc attggtgatc gtatattctg tgtaagggat caacggatgc ttttcaagat
     3841 aatcagtgta ctgctcttca ctgaattctg ctaatacggc tttgcccatc gcagaattgt
     3901 ataatggtcg ggtgattccg atttttgaag acatgcggat cgtttgatgt tttggatcta
     3961 gtttgttcac gtacaagatc tcattgttgt ccaatacccc taagtggata gtctcatcga
     4021 tcttttgctg cagctgttct aaaaacggta aagtcaactc taccaaatcg atttgttcaa
     4081 tgtttttatt cgcgtagcga ataagctttg cacctaaacg atagtttttc tctgaatttt
     4141 tatttacgta gccgatcatc aacaaagtat ctagtatttt caagactgta gaagaggtca
     4201 ttcccacacc ctttgcgatc gtctgcaaag agacatcttg gttttccgct aaatagtcta
     4261 gtattttaga ggctttgatc aatacagttc cataaggctt tttattttcc atataatatt
     4321 ctcctatttc tttataagaa aaattatagc ggaaatacca tcaatttaaa agagatatcc
     4381 agatataaac taccatttct ctttacaggc aatttaatgt tgaagatccg cttcgttttt
     4441 acatcaaact ttgatataaa gcaatgattt cttctactgt cgtttctctt ggatttcctg
     4501 gtgtgcatac atctcgcaaa gcatcttctg caattgctgg aatatctgct tcttttacac
     4561 ctaattcaga aatggtttct gggattccaa ccgctttgct caaccgatcg atctcaccac
     4621 aagccgcttc tcttacatct tctaaagaca tttcagctgc tcctttaatc cctagaacaa
     4681 gagcgatctc acggtacttt tctccagtat attctttgtt atatttcatg acagttggca
     4741 aaagtgctgc acacgctacg ccatgaggaa tgttgtacca tgcacttaac gggtgagcca
     4801 tcccgtgtac cagtcctaaa ccgacatttg agaagcccat tcccgcaata tactgtccta
     4861 atgccatttt ttctcgccca ttttgatcgc catctacaga agcttccaaa gaatggccga
     4921 tgatttcgat tgcttttaaa tgcagcatat cagtcatttc ccaagcgcct tttgtgataa
     4981 acccttcaat agcatgcgtc atagcatcca tacctgttga tgcagccaat tttttcggca
     5041 ttcccatcat catatcgctg tcgatgaacg cgacgattgg gatatcatga ggatcaacac
     5101 aaacaaattt tcggtgattt acttcatctg tgatgacgta gttgatcgtt acttctgctg
     5161 ctgttccaga agtcgttggt atagctaata taggtaaaca tggatttttc gtatcagcaa
     5221 caccttctaa actaatgacg tctgaaaact ctggattcgt caaaataatc ccaatggctt
     5281 ttgccgtatc gattggcgaa cctccaccga ttgcgatcaa acagtctgcc tctgcctctt
     5341 taacaaaagc cactccatct tttacatttt ggatcgttgg attaggtacg atcccgtcgt
     5401 ataaagcata agcgattgct gctttatcta gaagttctgt tacttttgtt gctataccgt
     5461 gctcgatcaa tcctttgtca gtaatgacag ctgctttgcc gaatcctcgc tgctgaaatt
     5521 cagggacgat cgactcaatc gctccttttc caaaatacga tgtttcattt aaaatcattc
     5581 gattactcat tttctattcc tcctaatttg tattattttt cacaataaaa acgaaagaac
     5641 cccaagcaac cggttgccca gttgcttgtt gctacagttc aaagactggc atcaattccc
     5701 aactgactgg agaggcatct ggatttgtct ccatgatatc ttccatgtac ttccaccatt
     5761 tttgattgat agatgtattt gccatttttt cccataactt ttcatcttcg atcactaagt
     5821 aaccaaataa caaacttgta ctcggatcaa gatagatcga atagtcgatg accccgtgtt
     5881 cacgaagtgc tgtacgcatt tctggccaaa gttcatcatg tctttttttg tattcttctt
     5941 gtttttctgg gtaaactttc atgcaaaaag cttttttcac catgtcagac acctgctttc
     6001 gtatgaactt cctccaaata acctgctttt ggagtgacac caaacgcatc tgctaaatgc
     6061 cacaggtttt cgtccgtgat tgtttgcaag attggtcctt gcgctttgac gtacgtatag
     6121 acttctgctg ccttttctgc tgtctcgatc aaaccaaaga cttcatccat gtcttttcct
     6181 gacccgtaga ttccatgttg tggccataaa accaatcgag tttctttcat tttttcagct
     6241 gttgcttccc caatctcatt tgttcccgga accatccacg gaatgatgga aattccttct
     6301 ggaaaaacaa ctaagcattc cgtacacatt tgccatagcg tacgactaaa ggaacgttcg
     6361 tctaattcat gcgtaaaact catcgctaat agatgactag catggcaatg cataacgatc
     6421 cgattatctg ggtctacttc taaacgggcg atatgactca tgaaatgact tggcaactcg
     6481 cttgtaggaa ggcattcgtt ttccagcccc cacaaaagtt ccagtgtttt gccatcttca
     6541 gcaactcgaa cgattccaag attctcggca ggttcgctcg ctacattttt aaaatatctt
     6601 cctgaaccag ttacaataaa atagcatcct gctaaacggc tggcatcaaa aatcatcgag
     6661 atgcggcgga tcactttttc aggatccaag aacggtgtga tctcttcttc ttttagtaaa
     6721 taagaaatat tcccgccatt tctttcatcc catcccaagc gataaagatt cgacgtcgtt
     6781 tcgatcattt ctttcacata aggcgcttgt aaaatatcta tttttttcaa tatagccaca
     6841 ctcctatttt cttaattcca acacgtcttt ttgatattcc tggacttctt ccagccaatc
     6901 caaaccaact ggaacttgat ttttgtaaca gaaataattc catacatcgg catacgggaa
     6961 atctttcaat tcttccgtat aagccattct tgaagtaaag tcaaaagcca gctccatttc
     7021 tttcaatcgc tcaactggtt ccagcatagc tttcagcagt gctttttgtg tatttctcgt
     7081 accgatgacc caagcagcga tacggttgat cgttgcatca aagaaatcca gaccgatatt
     7141 tgttttttcc aacaattcgt tacggactaa ttctttagcg atttcctgca attcatcatc
     7201 catcaaaacc acatggtctg aatcccaacg cactggacgg gaaacatgca acatgattcc
     7261 tttgctgaat aaagctaatg aagataattt attggaaatc acttctgttg gatgaaaatg
     7321 tccagcatct agacaaacaa gtttgtcacg agtcaacccg taacccatat aaaattcatg
     7381 ggaaccgact gtataagctt cagcgcctaa accaaatagt ttgctttcta ctgcatcttg
     7441 tacataccgt tcatctaact cttctgtaaa aatttcatcg agtgattcca ttaaacgttc
     7501 ccgtggggta aaacgatcaa tcggattatc tttcatccca tcaggtaccc aaaagttatt
     7561 gatacttgtt tgcccagttt ctttcccaaa gtactccgcg attttgcggc ttcttttccc
     7621 gtgttcgatc cagtattcac gaacttcttt atctggatga gccaatgtaa agccgtcttt
     7681 catcattgga tgcgaaaaga aagtcggatt gaagtcaaga ccgatttctt ctttttttgc
     7741 ccactctacc catttttcaa aatgtttcgg ctcaatttca tttagatcga cagattcttc
     7801 tgtatccaaa tagatagcat gaaggttcaa tttgtgtttg cccggtatca acgaataagc
     7861 cttctccaga tcttgtctaa gctcttcagg tgttcgtgcg gctcctggaa aattccctgt
     7921 cgccatgatt ccaccggtca attcgccatc cggtgtcaag aaacctttga catcatctcc
     7981 ttgccagcaa tgcatagaaa ttttgatgtc ctgtatcttt tctagtacag catctgtatc
     8041 tacaccgata gttgcatatt tttcttttgc ttgttcgtaa tttctttcaa tcgtgttcat
     8101 acgattactc ctttgatttt attcacgtac cattccatcg tgttttgctt attttcatct
     8161 gggtaaaaag tttcacatgg aaacgactgt ttgattacat ttcttgcttg ttctatattc
     8221 gaaaactgac ctgtactgag catttgcatg gcaacattcc cgattgctgt ggcttcacta
     8281 ggtcctgctt ctacaatgat tccggcataa tctgctgtca attgattcag tagacgatta
     8341 ttcgatccgc cccctacgat gtgcagcttt tccaatttcg ttccagttaa gtgttctact
     8401 ttgatcagct cttgtgcgta acaaagagca agattatcat acacacaacg agcgatagct
     8461 cccgatgaga cagggactgg ctgctctgtt tcaaaacagt attgctgaat ctcttctatc
     8521 atatttgggg gattcaaaaa tcgagggtca ttgatttcca tcacttgctg cagcggtttt
     8581 tcttttgcag caagctctgc caattccgca taactgtact cgtactcttg cattcgggca
     8641 acttcctgga tcaaccacat ccccatgatg tttttcaaaa aacgcaccgt gttatgggca
     8701 ccccattcat tcgtataatt ttcagaaaaa gcattgcgag aaacattggc gatctttgtt
     8761 tcaatcccta aaagcgacca tgtcccactg ctgatataac cccaacgttc tccttgacct
     8821 ggcgttccta atacagctga cgccgtatca tgacttgcta ctgtgataaa ggtcacatct
     8881 ggcaaatcat attttgaaaa ttgttctttt tgcagatctc ctagtatcgt tcccggctct
     8941 gtcaatggtg gaaataattc cttcgagaca ccgatttttt caagaagttc tatttcccat
     9001 tcttttgtcc ctgcattcag cagctgcata gtagatgcat tagttttctc cgtcaccatg
     9061 ttaccagtaa agacataccc taaataatca ggtatcagta acaatttatg tgcttttgcc
     9121 aaattttctt tttcttcagc aaacaattgg aacaaggtat tgaaaggctg gatctgaatc
     9181 cctgtctgct catacaactt atctagagaa tagatttcag aaaactgttc tactgctcca
     9241 ttggtacgct tgtcccgata agcaatcgga tcatttatcc gatccccttg ttcatcaatc
     9301 agacagtaat cgactgccca tgtatcgatc cccgcaaaaa ggcgatcaat ccctgtctgc
     9361 tttaattttt caaatccaat caaaatctct ttgataagat aatcgatctt ccagcgatcg
     9421 tgaccgtctt tgttccgaaa gccgtttttg aaccggtgta cttcttccaa gatcaaagaa
     9481 ccttttgcat ccctcgtact tttcattagt cgtccgcttg atgcaccgat atcgatggca
     9541 acaaatgttg gattcatttc tccacctctt ttactttatt gttgattagc actttattaa
     9601 taaagcgtta tcatttattg acaatgctat cataatacag aatcttatat tttgcttcac
     9661 actattttgg tatataattg cattatcttg acaagttggg agtgtttaca tggattactg
     9721 ggaaaaagcc aaccactcat ggtcggaaga ctcaaaaaga gtgatcttga cgcctacaca
     9781 aagaagcagg aatttatttt tttatatcca agaaatcggt tacttcaaag caccaatccc
     9841 ttactatact gaacgagcac atttaccttc ttacttgata aagtttactt tgtctggcaa
     9901 aggttcgctt acatataatg ataatcagca acagctaaaa gctggagact tattttttat
     9961 tgactgccaa gaatatcagc gttatcaaac gatcagcgaa gaaccatggg aaatggattg
    10021 gatccatttg aatggtcaga acgtccaatc attttatcag gagttcacaa aagacggcca
    10081 taacaccttc cattcaacag gagatccatc agaaaacaag atccaccatt tgatcacaga
    10141 attgatccac atgcaacaag gcacgaatgc ccgtaccgat ttccagtcct ctgtagctat
    10201 ccacgagttg ctgaatgaac tgattttgca aaagtatcag ctagatttcg aagaagagga
    10261 tattcccgcc tacgtttaca aactgaagca atacttagac gaacatttca aagaaacgat
    10321 tacacttgat caattagaac aacaattctt attgaataaa tatcagctga gcaaagattt
    10381 ttccaaattt atcggttctc caccaatcga ttatttgatc agcaaaaaac tttcttacgc
    10441 taaagacctt cttcggtata cagaatttac ggttcgaatg atttccgaag aaatagggat
    10501 tgagaatttt gcttacttta gccgcctgtt caaagcaaaa acaggactat cgccgagaga
    10561 ctttcgtaaa ttcagctgat tcatataata tgtacgtcat tttttcaaaa tattttgaaa
    10621 tatatagata aaaataaaat aaccgcagtt tctgcttcta tgtaaacaac agcagctact
    10681 gcggttattt tttagtgatc attctcattg ttcatcttca aaatgttcat aatgaaccaa
    10741 ctgtttctgt gtatcacgtt tcaaaaattc tttaggcgtt atgccgaact ctctcttgaa
    10801 tgctttcaga aaatgcggat aagaagaaaa accactttta ctatatacag cactagagct
    10861 gcggtattct cgcaacaagt gcttggcata gatcagcttt ttcttcatta catactgatg
    10921 aaacgtaaat ccagtgtact ttttaaattc tcgtgtgata tggtatttgc tgacaaaaaa
    10981 ctgcttttcc atttcctcta aagaaagcgg atgagataaa ttttttgaga tatattgtaa
    11041 catttgttcc acacgctcat taggaactac agcattctgt tcttgcgcac tctcttcttt
    11101 ttgtacaact tgattgagaa aaatcaagta ttctaccaga gcttgttcat attttatgtc
    11161 ttcaccgtaa atttttttat caggaggatg gtcgataaat gataattttt gcttcaatac
    11221 ttcctgttct atttgcaata cacgactcct cttctctccc attggttgaa aacaagccga
    11281 tagattagac catggcgtgg aacgactttc tagaaaagaa ggggtgacaa agatatagac
    11341 acgctcgaat acatctgaag attggcggac gatacgatgc aaatcattgg aatggatgag
    11401 cagcacactt cctgctttga tcgtaaattg tcgtccgttc aaataaaaag tcgcttctcc
    11461 ctttaatgta gcatggatct catagaaatc atgatgatga tagatcgttt tattttggct
    11521 gacgacatct ttgacatgat agatttcata ctgatcagaa accatcgtat tgacttgttc
    11581 accgctgatt ttcttttgga gcatgtgccg cacctccttt tgttcactta tgcacaattt
    11641 tattatacca cgttttttgt aatcaaaaag agctgctttt atatactctt ataaaaaaga
    11701 agagacgtgg catcttctag ccccgccccc tccattctaa atattagtta accaacgtct
    11761 tctttacatt attcaagaag acttcttcca taacgaatcc catcatcttt tgtttcttca
    11821 agaaccacat acaggtacgg acgattcttc atgatgattt ctttgatttt tgtgtactcg
    11881 atcacaccgt ctcccaaatt taccggcacg attttttcct gttcgacacg aaaatctttc
    11941 aaatgaaccg cacatatctt ttcaccaaaa cgttcaaaag cttcttctac caattggact
    12001 tgttcttgat aatcactact tgtgatcaaa ttggtcggat ctaaaatgat tcctagatag
    12061 tccgaatcta ctgcttggat cagctgctct acccttgcta aagaatacac cggatgattc
    12121 aaacctggtt ctatccccac catcatttgg tatttttctc cagcttttac caagcgacgg
    12181 ataacggaca cagcttcagc aaatgcttca tctgtgaaat tttcttccgt atattggatt
    12241 tccggcaaaa cacatccagt ttccgaagca accatcgacg caccaaagga agaagcatag
    12301 cgaagatact gctcgaactt tgtcagcaac tcttgtcgta tcgttaaatc tggatgaatc
    12361 atattgatat agcaacttaa aattcctacg gtcacttctt gcttttctaa aactcgtttg
    12421 acataatttc ccatcccaga attgatctca tttgcgccag aaggtatttc aggaaacgaa
    12481 agacctaagg cgagctgcag tgtatgaatc ccttgttctt ttgttttttc tgcaagatct
    12541 tctatcgttt ggacttcgga aagatcatgt cctctaattg taatgttcaa cataactatt
    12601 ctcctaactc agcatattgg gtagccacat gacgatttgc gggaagtaag taatcaaaaa
    12661 caagacgact aagataaccc cataaaaagg aagaagcggt ttcagcattg cctctgcttt
    12721 tacgcctcct acacttgcac cgacatatag tcctgtacct actggcggcg tgatggagcc
    12781 tacacacaga ttcatgattg aaaacaaccc gtaatgtaca ggatcaaccc ctacacttgt
    12841 gacgattggt aaaaatattg gtgtaaaaat caagatagca ggcgccacat ccataaacat
    12901 acccaccagt aataacacaa gattgactaa taacagaata ataaatttat tatccgttac
    12961 gcccataatc aacgaactaa ttgcctgagg aataccggta aacgccatgg cgaaagacat
    13021 catggaagaa gtagccaata agaacatgat cgtccctgac attgctactg attgaaacaa
    13081 catattaggt atatctttta gttttaccgt tttatagtaa aacatagcaa tcaacaggga
    13141 gtaaatgaca gctatcgctg aagcttctac tgctgtaaat atccccgtca agataccacc
    13201 gataatgatg acaatcaata gaaggctagg aatcgcctct tttattattt ttccagcatg
    13261 agccatctgt cctttttcga caacagggta tttattcttt ttagcaacga tgaatgctac
    13321 tagcatgatt cctagcgccc acaaagcgcc tacgagataa cctcccataa acaaagcaga
    13381 gatcgaagca ccaccagcaa caagtgaata catgataaaa gcagtacttg gaggaatgac
    13441 catacctgtc ggagctgacg cgatattgac cgctgtcgca aacttccggt catatccttc
    13501 ttccacttgc tgagggatca acactccgcc aatcgcggta gaagcggcaa tggccgagct
    13561 agagatggaa ccaaataaag cattccctaa cacattcgta tgagccaaag cccccggcac
    13621 gcgcccgacg aacaacatcg caaaatccac tagtttctta gctatccctc cattattcat
    13681 gataatgccc gagagaacga aaaacggaat agcgatcagc gaaaaactat tgatacttcc
    13741 caccattttt tgagctgaac taaaagcaga aacatcaaac ggtataacta acaataaagt
    13801 catcatcgat gagaatgcaa tacttatagc aatcggcatc cctaatacaa gcaacacaac
    13861 aaatacaaaa aataacacta atccggcttc tattgccatt ttattcctcc atttttatat
    13921 tttttcttga attgctggct tgttgcttaa tgtatcgatt agattgatca ggctatagat
    13981 aatgatgagt acccccgata caggtactga cagataaaca tatcccatag gaatacttaa
    14041 agaaggcgag atctgcccca ttgtcaatgt gacagcattc catccgccat acaccatgat
    14101 catcgcagca aataccagaa ataaactttg aacaacaact tctaaaattt tacttttttt
    14161 gccagttaat ttttcactta aaaccgttac ggctaaatgt gctttttgtc ccacaacata
    14221 cgcggaagac aacatggcaa accagacaag accgaatcga acaagctctt ccgtgaccgt
    14281 atttggattt cctaaaaccg ttctggaaaa tacttgccat aaaacaacag cgaccatccc
    14341 aacaagcaaa acagctccca ggatctctaa taccttgttt aaaatcattt tcatcacagc
    14401 tacgctcctt gctcttggat cttttgataa aggtctttgt aggtaggatc gtttttgaat
    14461 atatcatgaa gtggggcaac tgcctctcga aacggtgtat tatctacatc attgaattgg
    14521 actccatgtt cttcttgtgc taaagctttt tcttcttcaa ttgcttttgc aaaagcttca
    14581 atttcaaaaa ccgttgattc tttcgctgct tcttcaatgg ctttttcctg ctcatcagtt
    14641 agctgttctt tgatggcatc attcatgatg atgatatctg gcacacgtgt atgctcatca
    14701 taggaatagt atttagccac accaccatgt ccagctgtat acaagacaaa ttcattgttt
    14761 tctgatccgt tgatcaaatt ggattgaaga gacgtgtaca cttcatcact tcccataggt
    14821 acgggcgaac cgcctaaaag ctctaccatt ttgatagcgg tttcgctttg catcacacgg
    14881 atcttctttc ccttcaaatc ttccggcgta tggatcggac cgtctaccat ataaaagctg
    14941 cgctgaccag aatcataata ggtcaatccg gtaaatccta aatttttggt cgattggtag
    15001 attggctcca ttatttcttc attatccatc accttaaaga aatgttcttc atcattgaat
    15061 agataaggaa ctgaaaaaat cgaataatct ttagagaaac tttccaacgc tgaggcactt
    15121 acttttgtga aatctactgc tcctgactgt gtcaattcga tcagttcacg ttctccaccc
    15181 agttgtccat ctgggaaata ctggatctgt acggaaccat ctgttttttc ttttactaaa
    15241 cgcccaaatt cattcattgc atcaattact ggctggctgt tgcttgcata agcaaagcgc
    15301 aaggtaacta tctcatttac atctgcatct gcgacagttg ccacactaga attatttccg
    15361 cagccgctta gacctagcag acctaggcta agcgaacttg ctgcaaacag cagtgatgtt
    15421 tttttcatat gggtttcctt tcttttaaca ataagagacg agcaattctg tcaaacaaag
    15481 caccgttaac gactgtccat aaggcattgc tgtgattccg atattccgat aaaaatctaa
    15541 actgtccccc attcctgtcc cgattgaaac gttttgaact tctccttttt catcgatttg
    15601 ttcaagcaat ccttggatag cacgataagc gacttcttta tattcttgtg gtaaataacg
    15661 tttatggacc gctttcaaaa taccgtaagc aaatcctgca gttgcagaag attctacgta
    15721 agaagaagga tcatccaaca acgtatgcca taaaccgctt tcagactgat aagtttttaa
    15781 tgcacgcact tgtgcttcaa gtgtttcgat caataatttg cgcaatgcat cttctttcga
    15841 taattctaag atttcaatga tctctggaat agcaatcgtc aaccagcagt ttccacgagc
    15901 ccaaaatgct tcggcatagt tatgatttcc ttcaaacgtc cagccgtgat accacaatcc
    15961 tgttcgttta tccatcaagt atttgatatg gatcataaac tggtaacgag cttcttctaa
    16021 atattctggg cgattcaaca gtttcccgat ttttgccaaa ggaagcactg tcatcatcaa
    16081 tgtatcgtcc cacaactgat tcttattttc cggtccatat gtggcatgct gtaacccgtc
    16141 ttcatttgtc cgaggcatgt cattcatgac ccattctgcc cattgttcta aataaggcaa
    16201 atagcgtgaa tctttcgtgt cttcatacaa gtaagccata gtcaatagcg gtgccattgt
    16261 attgacgttt ttgggcggag cgccttcttc catacgatcc tcaaaccatt cattgaccac
    16321 ttgataagcg cgaggatttt ttgtcatctg gtaattttta taaataccat atagaccgac
    16381 accttgtggc caattccaca ctgtccagct tttgtcatct actttcagtc catcaaagtc
    16441 caacaaaaat tcaccattat cgtctttgat cgttgtcagg ttttcaacga gcaggtcaat
    16501 tttttctttc actaattctt taggtacaaa aatctcttct ttaataatca tctttacgcc
    16561 acctttttaa acgctttcat tttatatcct taatatagca gtaataccgt ccactataaa
    16621 tatcgctttt tgaacaaaaa ctgtctaaaa ttgacctaaa tgttaaataa caaaagtaac
    16681 tttcagttac ttggaaatta aaaaaagaac ttggagaaac aacgttttcc aagttctttt
    16741 tcatctattt tcttatcttt tttctacgct ttcttttgct tatccgttgt aagcatcaat
    16801 gatgatctgt ttcaattcag agatcaatgg ttctttcgga ttagctgtcg tacattggtc
    16861 ttcgtaagct aattcagcca tacggtctac ggttgtatct agtgtttctt gtgtgactcc
    16921 ttgagctttt agactcatgt tgatgccgac agattttcct aattcataaa cagccgttgc
    16981 taaagcttcg actaattcct ctgttgtttc gcctttcaga cctaagaatt ttgcgatatc
    17041 tgcgtaatct gtatctgcac ggaaatagtc atatttaggg aacatcgcat gtttttgtgg
    17101 atcttttgca ttatagcgga taatatgcgg taaaagaatc gcatttgtcc gtccatgagg
    17161 gatcccgtat tccccgccga ttttatgtgc gactgagtga caaataccta ggaatgcgtt
    17221 agcaaacgcc ataccagcca ttgtagaagc gttgtgcatt ttttcacgtg attccatatc
    17281 aggtgttttt actgattttt ctaaatagtc aaagactaac ttgattgctt gtaggctcaa
    17341 tccacgtgta taatctgaag ccatgactga aacataggat tcgattgcat gtgttaacac
    17401 atccatcccg gtatctgctg tgacagatgc tggaactgac atgacgaatt gaggatcgac
    17461 gattgcgaca tctggcgtca atgcataatc tgctaacgga tatttcacat gtgtttcact
    17521 gtcagtgatg accgcaaatg gcgttacttc agaaccagtc cctgatgttg tcgggataca
    17581 tacgaattgt gttttttctg gtttgtcgat cttatatgtc cgtttacgga tatccaagaa
    17641 tttttgtttt gcaccaaaga aagatgtgtc tgggtgttca tagaacatcc acattccctt
    17701 agctgcgtcc attgcagaac cgcctccaag agcgattact gtatctggct tgaagtctgc
    17761 catcagtttc gttcctgcgt atacggtatt tgtcgatggg ttcggttcaa catctgagaa
    17821 gacttcgatc ttcacatcat ttttacgtcg tgccaatact tcacgaactg tatcgcagta
    17881 accgaattgg accataccag ggtcacaaac gatcatgaca cgttcaacgt tttccatttt
    17941 ctctaagtac aatagagagt tcttttcaaa gaagattttt ggcggtaatt tgaaccattg
    18001 catgttattt ctccgtttcg ctacagtttt gacattgatt aagtttacag cagagacgtt
    18061 acgagaaaca gagttcttac cataagaacc gcatcccaaa gtcaatgacg gaatcatttc
    18121 gttatagata tcaccgatgc cgccttctgc agatggtgta ttcactaaaa tacgacaagc
    18181 tttcattcga agaccgaatt tgacatgcaa ctcttcgttt tctgaatgga taactgctgt
    18241 atgtcctaat cctccaagat tcaacatacc ttcacacaaa tcaaacgcat ggtccgtgtt
    18301 gttagctttg atcatggcaa gaactggaga aagtttttct cttgatagcg gataatctgg
    18361 gcctacgcct tccaattcag caatcagcat tttcgttcct tttggtacac tgattcctgc
    18421 caattttgcg atttccatcg cagaatgtcc aacgattgat ggattgaccg catattttcc
    18481 ttcgttcatc actgcatctt ctaatttttg caattcatct ggttttacga tataaacttg
    18541 gtgtgcttgg aattctgctt ttactgctgc atagatttct ttatccacga tcacagcttg
    18601 ttcagaagca caaatcattc cattatcaaa tgttttcgaa acgatcaaat cgttcactgc
    18661 acgtttaatt tttgctgttt tttcaatata agctggtacg ttacctggac ctacacctaa
    18721 agctggtttt cctgtagagt aagcagactt gaccattcca gctccacctg tcgctaagac
    18781 gatcgcgata cctggatggt tcattagcat agaagtcgct tcgatcgaag gatgttcgat
    18841 ccattggata caattttcag gagctccggc agcgatagca gcatcacgta ccactcgtgc
    18901 tgcttctgca gaagattttt gggcacttgg atggaaagca aaaacgattg gatttcttgt
    18961 tttcaacgcg atcattgatt tgaaaatcgt tgtggaagtc ggattcgttg ttggagttac
    19021 tccgcaaacc acaccgactg gttcagcaat ttcaatcaac cctttttgga catcttcatt
    19081 gatcacacca actgttttat catgtttgat attatgccaa atatattcgg acgcatacat
    19141 atttttgatt gctttatctt cgtaaacacc gcggcctgtt tcctctacag ccatcttcgc
    19201 taatggcata tgttgatcca aagctgccat tgccatttca tgcacgatat ggtctacttt
    19261 ttcttgatca aagctttcca tttctttcaa tgctgcattt gctttttctg ccaaatcatc
    19321 aatcattgct tgtacgtcaa ttgtcttcgt tttttctttt tctattactt tagccatcat
    19381 tatcctccta atgggtcatg gttatttgtt aaataattca catgtatatc atacaatatt
    19441 tatttttcta tgtaaacact tttttgtgat ttttttcaca gttattttta aatataaaat
    19501 tgctttattt acaggtgttt gtatagaaaa atatataaag ttatttatta ttatttatat
    19561 gacacacccg attattcaat attgagcaat atatcccatg ctcttatctc tttctttttt
    19621 gaataaaaaa tgaggtagga catctttctg ccctacctcg tctttaaata agctttgata
    19681 cttatttttc ttccttctct tctgtctctt ccagcgtttc tgttgtttca gtttttactt
    19741 caactgtctc agctggttct tctgttgttt caacagtagt cgttgcatca tttgttacga
    19801 cagtccctgg tttgaccgtt ttgattgctg cacgatcgta ctcaaggaag atcccttcgc
    19861 agtctaaaac aactgtccgt ttgtcattgt cgatttctga aacaactcca tgtaatccgc
    19921 cgatcgttac gactgaatca cctggtttca tgctatctaa caagttttga cgttcttgct
    19981 gttgtttctt ttgcgaacgt gacataaaaa accacattgc taatagcgcg ataaacatca
    20041 caagcattgg taatgttccc atttttttca cctcactaat tctgtatcta caaaaaacac
    20101 tttagcagaa aaatgctgat aacactagtt ttttacttaa tttttaaaag attttccttt
    20161 agaagctttt tgcgttttct ttattgaacc cgtattcttc aaaaaaggct tctctaaatt
    20221 caagcaaatt atcatccatg attgcttgac gtacttgttt cattagattc aacaagaagt
    20281 ataaattgtg gtaagaagtc aaacgaatcc caaatgtttc atcacatttg atcaaatggc
    20341 ggatataggc acgtgtatag tttttacatg tataacaatc acatttctca tcaattggac
    20401 ggaaatcatg ggcatatttc gcatttttca ctactagacg gccttgagaa gtcatacatg
    20461 tgccatttcg agcgattcga gtaggcaaga cacagtcaaa catgtctact ccacggataa
    20521 caccatcgat caatgaatca gcagcaccga cacccatcaa gtaacgtggt ttgttttcgg
    20581 ggatcaacgg tgtagtgaat tctaatacac gattcatttc tgatttaggt tccccgacag
    20641 ataacccgcc gattgagtaa ccagggaaat ccatcccgac tagatctttc gcgctttgac
    20701 gacgaagatc ttcaaaccct gctccttgga tgattccaaa taatccttga cggtctggat
    20761 tagcatgagc tttcaatcct cgttctgccc atcgagacgt acgttctact gattttttca
    20821 cgtagtcgta actttcatcg aatggtggac attcgtcaaa actcatcatg atatcagagc
    20881 ccaatttatt ttggatgttg attgcttttt ctggtgataa aaacatacgc gaaccgttca
    20941 agtgattttt gaaatgcacg ccttcttctt cgatattccg catatcactt aatgaaaaaa
    21001 cttgaaagcc gcctgaatct gttaaaatcg gttgatccca gttcataaat ttatgcagtc
    21061 cgccagcttc ttctactaag tcttcaccag ggcgtagcca taaatgatat gtattactta
    21121 aaataacgcc agcacccatt tctttcaact cttctgggga cattgttttt actgtagcta
    21181 atgttcctac tggcatgaac attggtgtgg ggaaagttcc gtgtggcgtg atcaattccc
    21241 ctaaacgcgc gccagtatgt ttttctttct tgattaaacg atagcgaatg gcaggttgcg
    21301 tcattcattt ccctactttc tatataaaat atcttgacaa ctcccaccat cataatcgtt
    21361 tcaagtgctt tttgcaagtt ccctcggctt ccttctactt tatttaatat tctttttttt
    21421 atcctttttt tatgaataac aaaaaaaaga aaaacattat gacagaaata ttttttgata
    21481 catggtatat tggtgttatt aaagaaaagg agggaaaaat catgcaatct tctgcagaat
    21541 taaaacgcca agcaaaagag agtctaaaag gacgttgggg acaagctgtt ttactaaatc
    21601 taatccctac attgattggt attgctacta ttcttcttat tatgattcct attatcttgt
    21661 ttgccaccac catatatgat ggatcagcga gcgtctcaga agcgacaact tcaggaggcg
    21721 gtagttcagg aggcggtggc ggaattattt ccagcatcat tagcgctttg ttcatgagcg
    21781 gtatttcttg gacttatctt gatattttac gtggacaaaa agatcagatc gaaccattca
    21841 aagatgcatt tcgtggattc aaaggtttgt ttatcggcgg agtgatcagc ttagctgtgc
    21901 tgatctcgat ctttacaaca ttatggggtt tgctattagt tattcctgga atcattaaaa
    21961 gctattctta ttctcaaagc tattttattt actacgatat cgtccaagaa acaggacaaa
    22021 cacctaaagt actggatacg atcactgcaa gtcgaaaatt gatggatggt tataaaggac
    22081 aacttttctg gttagatctt tcatttatcg gctggcatat cttagcatta gcaactgctg
    22141 gtattggtta tctatggctc agcccataca tttctgcaac aaaagcagca ttttatgaac
    22201 aattgccaaa agatatttaa aagagagtgt gacttgtgac cgagggggtg gcaggagaac
    22261 accgtttatc gagaggcagt aaaagaaaca ttcagcccat tagcaaaaag gaggtgtgac
    22321 aacattcatg tcacacctcc tttttgtata gttccagtaa aaagaaaatc aacttagaaa
    22381 cagttaatca ttcctcttct tctgcttccg gtaatcgatg gaacttgatc agttcattca
    22441 ccgcgattgg tacgatagat aaaatcccta ccaagaacca gtgattcaaa ctgatgtgta
    22501 ctaggccgaa tagttcttgc gtaaatggca gcaaagcaac agccgttgta atagctaatg
    22561 ccagtaacgc catttctacc aaagctttat tggtcgctaa attgactttg aagatcgatt
    22621 ggctgctgcg tacattgaac acatgcagaa tcgatgaata agctaagatc aagaatgcaa
    22681 cagtttgacc gacatgctga cttgcgtcta cccatgggct gatagtatcg acataactac
    22741 ctaaataata accaaacaag gttacgatgg tgaagacccc tgcatttatg gcaatttttt
    22801 gcaataaacc tcgagcaaag atcccttcat ttttcggaat gggtggctga tccatgatgc
    22861 cgtgttccgc tggctctctt cctaaagcaa atcctggaag tccatcagca actacattga
    22921 caaacagtag ttgcacagct gtaaatggtg ctccccatcc taacagcatc gcaatcaaaa
    22981 caataaagat ctccgaaata ttacagctta gcaaaaagtt gatagcttta cgaatattct
    23041 gataaaccga acgtccttga ctgacagcgt ctacgatcgt cgcaaagttg tcatccgtca
    23101 aaatcatatc tgcggcactt tgcgccacat ctgttcctgt gatccccatg gcacacccaa
    23161 cgttacttgc tttcaacgct ggtgcatcat tcacaccatc cccagtcatc gctacgactg
    23221 cacccgtacg ttgccaagat ttgacgatcc ggatcttgtc ttctggcgtt acccgagcat
    23281 agacagagag agctttgaca cgcgcatcta attcttcgtc tgataattga tgcagttctg
    23341 atcctgaaag tgcttctgac ggatcattca agatacctaa ttctttcgct atggcactgg
    23401 cagtcaccac atgatctcca gtgatcatga ctgttttgat gccagccttt ttcgctcgct
    23461 tgattgctcc tttactttct ggacgtggtg gatcgatcat tccgatcaga ccaatcaaac
    23521 gtaagtcttt ttccagtgct tcagaagaaa tatcttgcgg ttcttcgtca taagtagcat
    23581 aaccaacagc aatcactctc agtgcccgtt taccaaagcg atcattaacg atcgccgctt
    23641 gttctacatc gcctgaacta aagcgcggag caagaacatc gaatgctcct ttggtgattg
    23701 agatgtattt ttcgcccatt tggtgaactg ttgtcatcat ttttcgttca gaatcaaaag
    23761 gaagctcgtt tactcgtgga tatttttctt ctaattctgc ctttgtatga taattctctt
    23821 caacagccct tacgatggct acttctgttg gattaccttt gataacaagg tcgtcatctt
    23881 cttgctcgac cgtcacatct gtacatagtg cagccatttt caatatttcc atcgcgctgt
    23941 tcgtcattga atcttcgata ttcgttactt catcttcttt gctccatacc cggcggacgc
    24001 gcatttcatt ttgtgtcagc gttcctgttt tgtctgagca gataacatta gcggttccta
    24061 gcgtttcaac tgctggcaac tgtcggatga tcgcatgttt cctcgccatc ttctgcacac
    24121 cgtatgcaag tgtcaacgta acaataacag tcaaggtttc cggtacagct gcaacagcca
    24181 aggaaatcga agtcatgaac atctcaagga gtggttctcc ttgcagttca ccaatcacaa
    24241 atactaaagc cgcagccgct aaagcgatca tactgattcg tttgcctagc tgattcaatc
    24301 ggacctgtaa aggtgttttt tgcatagtat tttcgttcaa aagatccgcg atcttaccca
    24361 tttctgtagc catgccaatg gcagtgacga tcgctttccc acgacctgca gcaaccgtac
    24421 atcctttaaa taccatatta agttggtcac ctaatgactc atcttcttca gcaataaatg
    24481 ctgcatcttt ttcaactgct tcactttctc cagtcaacgc cgattcttct acacgtaatt
    24541 gtgatgcttc gatcaaacgg gcatcggcag aaatagcatc accggactct aaaacaagaa
    24601 tatcacccac taccagttgc tctgactcaa cagtggtcac tttgccgtct cgtatgacag
    24661 ttgccgtttg tttattcata tcttgcaagg attccagtgc tttttctgcg tttccttctt
    24721 ggacaatcgc caataccgag ttgatcacaa cgatagcgat gatcagcagt ccttcaaata
    24781 aatccccatg ttctgtagca aatgcggtat aaaaggaaat caccgctgct acaagaagga
    24841 tgatcgttgt aaaatcggac aagcttcgaa agaatttttt gatcatcgat tctttcggcg
    24901 cctcatcgaa tttattcaat ccctgctttt ttcgccgttc atccacttct tgtgaagaca
    24961 acccagtatc tggatctgct tctgttacct tctttacttc ttctattgtc tgcttgtatt
    25021 cttccatcct attcctcctt taaaatcttc gtacaaaaaa aggtacttat tttactataa
    25081 catccttttt ttatttactt caaataaagg gcttatcgat tatttgttaa gaaagcgtaa
    25141 aatttaaagt gcttatattt gcaaacgcta ccaaaggatg ctattatata gatgtaagga
    25201 aggaggatac catcaaatag acagaagaat ttctcgatag aacagtgtaa gcaaacaaag
    25261 ttgttagaag tacaggtttc acccagacat gcgtgtagag tacaaaccta taaatagtga
    25321 atgcgtatgg atgtttggat cacgaagtat ccgaaacaag aagtaatgcg atacgtaaca
    25381 attgaataac gtaaacgtct gaaaattgaa taggaacaag agatgtttca aatgttgaag
    25441 atgtaacgaa aacaaaattt ttgtttaaca tgaagaaatt caacaccgtg ctttgcatgt
    25501 atgatggaaa gttacaatca tttctgttta tttgaatcct tccgaggtac aagaaagccg
    25561 agcttatcga gagctcggct ttttctttgt cataaaatct ttgtaaagct tttttgttat
    25621 tcaaaactag cggcttttca taaccttatt tcacgaacat cgcatctcca aaactaaaga
    25681 aacgatagcg ctcttcaatc gcatgctggt aagcagataa agtcaattct cttcctgcaa
    25741 aggcactaac taacatgact aaagtcgatt ttggcaaatg gaaattagtt gagaaagctt
    25801 ctaccacttt gaattcatag ccaggcgtaa tgaaaatatc agtccatccg ctgtctgctt
    25861 tgatttctcc attaaatttc gttccaatcg tttctaatgt tcgaattgaa gttgttccga
    25921 cagccacgat tttcccgcca tttttacgta cttggttcaa tcgctcagcc gcttcttccg
    25981 tcaaacggta gaattcacta tgcatatggt gttcttcaat tttatctacg ctgacaggtc
    26041 ggaatgtacc taaccctaca tgtagtgtca gatagactaa ttcaacaccc tttgcttcga
    26101 tctcatcaag taattctttc gtaaaatgca atccagctgt tggcgctgca gcagaaccat
    26161 tttctttcgc atagacagtt tgatagcgat ctgggtcttc cagacgttct ttgatatatg
    26221 gaggcaatgg catttctccc aatgattcaa gaatctctag aaaaattcct tcatactcaa
    26281 agtcaatgat ccgtccgccg tgttccaatt cttctttcac tactgcttgc aatctgccat
    26341 caccaaaaga gattcttgtc ccaactttgg cacgtttcgc aggtttgatc aatgtctccc
    26401 acgtatctcc ttgtgtattc gttagaagaa ggacttctaa atgcgcacca gtatctggtt
    26461 tttctccata taaacgagca ggcagaactc gtgtattatt cataactagc gcatcaccag
    26521 gctgtaactc ttcaatgatt tcatggaaat gtttatcttc catctctcca gttttccgat
    26581 ccaaaacaag taaacgagaa tgatcgcggt cttttaatgg tgtttgtgcg attaattctt
    26641 ccggcaagtc aaaatcaaaa tcttctgttg ttaacatatc gtcactcact ttctatcatg
    26701 tgcttcatca ttctatcatg tttttcgttc tgttggcaaa atcagcactt tttcacttct
    26761 attttttgtt ttcctaaata aaaaaactac cctatttgta ttttttcatt gttttaggca
    26821 tactagtaat agatagttct tcattgaaaa tagaaaaaga ggtggcacca tgattgaatt
    26881 tcaaaatgtg tcaaaaattt ataaaggtgg aaaagtcgct gtagaggacg tcaatctttc
    26941 atttgaaaag ggtgagttca tttgttttat cggtacgagc ggaagcggaa aaacgacgac
    27001 gatgcggatg atcaaccgaa tgactgatcc aacacaaggg aaaattttga ttgatggaaa
    27061 atccatccaa gaaattgatc cagtggaatt gcgacgtcag atcggctatg ttatccaaag
    27121 tattggattg atgcctcaca tgacgatccg tgaaaatatc actcttgtcc aaaaattgtt
    27181 gaaagtcagt caagaagaac ggaataaaac agctgaaaaa atgattgatc ttgtggaatt
    27241 gccccgtgag atgttagatc gctacccaca tgaattatct ggtggtcagc agcagcgtat
    27301 tggagtcgtt cgtgcccttg cagcgaatca agatatcatc ttgatggacg agccattcgg
    27361 tgcgcttgat ccaatcactc gtgattcctt gcaagacctt gtcaaagatt tacaagagcg
    27421 tttgggaaaa acgatcgtat ttgtaaccca tgacatggat gaag
//
LOCUS       DACGMI010000038        27318 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.039, whole genome shotgun sequence.
ACCESSION   DACGMI010000038 DACGMI010000000
VERSION     DACGMI010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.039"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..280)
                     /locus_tag="IXT46_001820"
     CDS             complement(<1..280)
                     /locus_tag="IXT46_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4947730.1"
                     /translation="MSITKNIKCTDEKTSHSIKQILNIKDSHITFSKDAISKERVHGR
                     MANVFTGLLTGEAHRCECCGFDSVIRHAYHDSWIQLLPYQEVPTYLHLY"
     gene            complement(428..986)
                     /locus_tag="IXT46_001821"
                     /pseudo
     CDS             complement(428..986)
                     /locus_tag="IXT46_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302360.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1155..3266
                     /locus_tag="IXT46_001822"
     CDS             1155..3266
                     /locus_tag="IXT46_001822"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012579.1,HMM:NF013070.1,HMM:NF019826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAQ4947731.1"
                     /translation="MNTKDLKLLETIVRSHVTNSQQLKSLVHFSTRQITYSIKKINDE
                     LSLHGLSLIKRSNSGEWLYEANDLQKLLIYMNQAMVFKEGAIPEYINDDLAYSEIRRY
                     SELLFILANPKKVTTQEIMAFIGISKNTARNDFSKIKKELPPDYTLIFDPQNGYMIES
                     SMAKLHTLLLEVFNYLFERHATVNRFESLFSEEREFVGFFIHTYEQTFKLKFSDNSLT
                     KLYYLIGLSLSSFKRRTKGQIDFSYDLQELDEFQMIRSCIDQHYQHAEIAIDYEWLTL
                     LFLSFNTISNEFEILDSRIYQVIMEMITLFQSKSAIRISNKEELTNRLMNHLRPAIYR
                     IRYELPFEIDDLAEIVKENHEVSAVLNFVKESIVPLEAFLRKTIPETELYLISVYFCS
                     ELLNSSIIETPVRKKAIVVCSNGLIMANVMAKTLKEIFPDIQFVASSSVREMDKFVED
                     VDLIFSNQPLKSEIPLYIIQPIMNEEEKNRLRNRVLIDFSTNNISKETRNLTEIIKRY
                     SAVQNEESLQTDIERFLINYANSLIYLDRQSKQAQKISFVELLVSEGIILVSTKQLTW
                     QNAMELSCQPLLKEQVINQNYQTILMSQMADEEAYYFLNNRIAIPHSSPENGVIKGGC
                     SLLISVDPIIFPGNRPIHFISPFAIGKKENYLLAINQLLQLSKDEEYQQEILLCTTED
                     EVRKKIKNFLRRKQYVNNEFS"
     gene            3244..3894
                     /locus_tag="IXT46_001823"
     CDS             3244..3894
                     /locus_tag="IXT46_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAQ4947732.1"
                     /translation="MSITNFPELTIILRGYSFEEAMFVMEELAAMNTSVGIEVTTNND
                     DFARIITEGNKKFGQQLLIGAGTVLTFSQADQAIAGGAKFLLGPKKFSTPIFSLAKER
                     GVVTVPSAFTPSEIQVMFDEGADIVKVFPAVTVGPTYFKQLAGPFGIRPLMAVGGVTI
                     DNIAAFKKAGVVYFGVGSSMFQKADIQNRNGQAIRKSIQSYLDKLAEAGSEEDESH"
     gene            3881..4333
                     /locus_tag="IXT46_001824"
     CDS             3881..4333
                     /locus_tag="IXT46_001824"
                     /inference="COORDINATES: protein motif:HMM:NF012579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4947733.1"
                     /translation="MSLIKLEEKNILLNQSFSNQEEYFQKITKKLMTENMVKEGYLES
                     ITKRETTYPTGLYIGERSIAIPHTDYQLSNVTAILVSVLKDSLHFQRMDDPEEMVSVN
                     VIIHLLFDSPDKQPQLLKELMSKVTNQDFLQAIMEAKSKTEVLTAFNQ"
     gene            4350..4655
                     /locus_tag="IXT46_001825"
     CDS             4350..4655
                     /locus_tag="IXT46_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIB"
                     /protein_id="HAQ4947734.1"
                     /translation="MSKKTIIVACASSMITSTMAANKIRKIAKTNGLPEPRILQLKFS
                     EVAGALESNQVDFIVPTGKLQENVTKGIKVIPGTPFVTGVNEEKSESLVLEALKELD"
     gene            4667..5944
                     /locus_tag="IXT46_001826"
     CDS             4667..5944
                     /locus_tag="IXT46_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010492829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IIABC"
                     /protein_id="HAQ4947735.1"
                     /translation="MNIVIDALNWISSLGPMIMMPIIILILGLFFRIKLNTLLKSALT
                     VGIGFAGVNIIINWFISQVGPSVQLMVKNWGIQTSIMDVGWPARAAATWSFPLAAVMV
                     FIILGINVLMLIFKKTNTVMVDFWSYNHYIFVAALVYYATDKNIILAVIFGAIDAIIS
                     FKLADWTTPLVEDYFELEGVNFPTANSVGWAPLAWLLNKLWDRIPGLNKVDARPEKIQ
                     ERFGFVGEPMFMGFVIGLVIGLLAKEPVDKVLIVGMSTSATMVLTPKMMQILMEGLLP
                     FANSVKKFLNVKFPGNNFTMGVDAALTVANSSAIATGIIMVPITLVLAAILPGNKLLP
                     ISDIAYQAMWLSAWPVAFSKGNIIRGILSTTIITACVLLIATSLAGIHTQLALAGGFQ
                     LPAGMTQISTEDAGTHIIGFILMKIAEFISNIF"
     gene            5963..7111
                     /gene="dgoD"
                     /locus_tag="IXT46_001827"
     CDS             5963..7111
                     /gene="dgoD"
                     /locus_tag="IXT46_001827"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HAQ4947736.1"
                     /translation="MKISKITVYKVKPRWIFVKISTDEGIEGWGEMISGTKTETVVAG
                     AYEIGNRFLVGQNPFAIERLFQEMHRSFFRGGPINGTIVSGLEMALWDIKGKALNVPV
                     YELLGGAARDKIKVYSWIGGDRPSEVVEQAQDRVDRGFTAVKMNATEELHYIDSYEKV
                     AEVVERVASIRERFGDTLSIGVDFHGRVHKPMAKVLAKALEPYHPMFLEEVVLPENEE
                     HFSEVANAVAVPLATGERLYTRWQFKSILQQGAIDIIQPDVALCGGILETRKIAAMAE
                     AYDIAVAPHAPYGPIALAATLQVDSCTPNVFIQEQSLGIHYNKGFDLLDFVKNKEIFQ
                     YKDGFVDLPTKPGLGLEMDEDRVKEIAQEGLVWTNPKWKNYDGTIAEW"
     gene            7123..8025
                     /locus_tag="IXT46_001828"
     CDS             7123..8025
                     /locus_tag="IXT46_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryldialkylphosphatase"
                     /protein_id="HAQ4947737.1"
                     /translation="MINTVTGPIEAESLGTTFIHEHLYVIPNELRKYEDYTLDDIYHS
                     IAEVMAFKQAGGKTIVDLTPINYGRNPLALKMISEATGVNVAFVTGFHKEEFQPKWLT
                     TLNDDEIFELLYSEITHGVTSQNLLPGAMKVGTSKNEVTLAEQRILAIAGQVQKKTGI
                     PIITHCDGGTMGLEQINCLTKNGAKASNICLSHVDLTKDFHYLAQICETGASICMDHI
                     GRELANHDADRVQLIKRLVDAGYENQICLSGDMGRKKYLPTYGGTPGLTYILTSLKEE
                     LLKVMSEPTFNKMIEMNPINILSK"
     gene            complement(8694..9080)
                     /locus_tag="IXT46_001829"
                     /pseudo
     CDS             complement(8694..9080)
                     /locus_tag="IXT46_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252556.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9140..9820)
                     /locus_tag="IXT46_001830"
     CDS             complement(9140..9820)
                     /locus_tag="IXT46_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HAQ4947738.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGITA"
     gene            9903..10052
                     /locus_tag="IXT46_001831"
     CDS             9903..10052
                     /locus_tag="IXT46_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit S"
                     /protein_id="HAQ4947739.1"
                     /translation="MKAIINSKDYEGYKAKHPEAKPFKYPQEMKRAWRKMLDDELIPL
                     ENELR"
     gene            complement(10801..11414)
                     /locus_tag="IXT46_001832"
                     /pseudo
     CDS             complement(10801..11414)
                     /locus_tag="IXT46_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406632.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(12635..13339)
                     /locus_tag="IXT46_001833"
     CDS             complement(12635..13339)
                     /locus_tag="IXT46_001833"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012610.1,HMM:NF019322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4947740.1"
                     /translation="MIFDKVKEQIRKVYITTDRKSELLPSERDLAQEFSVSRPTIRKA
                     LASLEDEGIISKNEGRGYLVKPASEKYVDHELDSFIGFFQDAVQQGKKISSKIIQQTI
                     IPADSTISECLEIEQNTLVLVLERIRYIDDYPTCIAKSCIPLSVLPEIVEHDFAKESL
                     FSVLESRGIRLAYAKRSIEVTPPTDLENLYLDLEKNEPVFVFTSIGFAKNQKPFEYEI
                     SKYPAYKTKFESTVSK"
     gene            complement(13354..14223)
                     /locus_tag="IXT46_001834"
     CDS             complement(13354..14223)
                     /locus_tag="IXT46_001834"
                     /inference="COORDINATES: protein motif:HMM:NF012585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947741.1"
                     /translation="MKIAVICSGGDSPGMNSALLAIKKTIDSEPDSEVVFFKNGYAGI
                     FKECIASVSLKEVEVFKAGTLIGTARFEKMRDLESRKIIIENLNKMEIDNLIVIGGNG
                     SLKGAELLKNESELQVSVIPGTIDNDFPNTDYTLGFDSALNTIIRSIDDLTSTANAHD
                     RIIIMEVMGRGCFALPEYASIANNTYWVERDDKEYLHLICKKFESEFYSPILLLPEGI
                     SNKQKIIEFITKNLPKETKYLNLAYLQRGSSPTFYDRYIGYLWGQLAAKELIEGKSGI
                     LSQKNGNIMLIPW"
     gene            complement(14331..15347)
                     /locus_tag="IXT46_001835"
     CDS             complement(14331..15347)
                     /locus_tag="IXT46_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003526912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4947742.1"
                     /translation="MFNFDQERFLKTQAGAVATNEQISNILESIASDLEEIYFIGSGG
                     VGILFDSTIEFARTRSTFPFHRVIAAEFMIHPNKTFSNKSLVVIPSLSGTTKETLELV
                     EYCNEMNVKTLALVGSPKTPLEKAATYSIYNDVLDDTSSENYYLQGLLIALFLMKQRN
                     EIDINQYNTYIEDLKKIPEALVHAKEQAEPMAKSFAKKHKDTSYHILTGAGDSFAEAY
                     YYGMCILEEMQWIKTRPVHAADFFHGTLELIEAGVSVIITEGEDDSRPLTERVKNFVP
                     KFTDVHVTVDTKDYDLPGISEDTRKIISPVVLATVFERISAFLEEERNHPLTTRRYYK
                     QMEY"
     gene            15537..18260
                     /locus_tag="IXT46_001836"
     CDS             15537..18260
                     /locus_tag="IXT46_001836"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012385.1,HMM:NF013070.1,HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4947743.1"
                     /translation="MKTKILKELNDLLNSYDFPQYFPEECNAQYIAQKFQIKRNTASK
                     HLNELMEQKKVVKINGRPVLFFPVHTIERYISHSLDSFEFSSIDSFREKISKKKADHF
                     FDDLIGAKQSLKEAVQQGISAMKYPGGLPIMYFGSSGVGKSYLVEKLAEYCRQTGIIH
                     ENAPFIELNCAQYFNNPELLTSQLFGHMKGSFTGADSDHIGIIEAADGGIVFLDEIHR
                     LPPEGQEKLFIHMDKGVFRRVGDSGPWRLSHVRYIFATTEQEENFFLETFRRRIPIVC
                     TLPNYQDREISERKEIVFHLLEKESTLINKEILVSEAALSFLIRLDLYGNIGELDGLI
                     KQTIANKLFSGSNKKYIEIHISDLPSRYLLTENIELKNQIASQRFYIFSNGNYVHDCD
                     ETSTVTTNLRGLIHRVSKYYSECHDVNRNSEEFRRFVKDQMAEFNDRFIYQKNSEVLV
                     KYYLPEIQNIVQKISPSLFVHLSGNTVQAIATYLAIRDQWGYGKENASANEIEKLYEN
                     LKCNYLTDLNVFLLIFENALDTTLTIWDKLYISLCVISETGNEAKDINAIILAHGYAT
                     ASSIANVANRLVNQFVIDSIDMPLDISFSEVIDRLLHYIEYRKPKDGLVIFVDMGSLA
                     QIKTEIEQVIEVPTMIINNVTTEMAIETAQLIQSTSDIQKVVKKLPYSQFEKQVLYPI
                     KIRKRTIVVSCNTGLGTSIKIKEMMENNLSKDLGIEFLPYENETLRDTQQLEFLIKTK
                     DIIAIIGTDDPRVSNIPYISLEELFDGEIGKLYKVLLRVYGKEIAEAINQNIVKNSSL
                     NRLIDSLTILDAEKVVNQIEESLKDYQMRVGKTLSSLSKINLYVHISCMIERLIRNQG
                     VSSYPAIDQFLKRYETEVASIQKALSKIEKLYNIKIPMEEIAYVCNIIVSY"
     gene            18388..18810
                     /locus_tag="IXT46_001837"
     CDS             18388..18810
                     /locus_tag="IXT46_001837"
                     /inference="COORDINATES: protein motif:HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose IIA subunit"
                     /protein_id="HAQ4947744.1"
                     /translation="MRQILCMSHGPLAKGMIETLSIIVGDLDNIDFRCAYVDGNNDVE
                     MIIDDYLKESMGNETIVVTDIFGGSINNEWLRRLPDLSKVYLISGMNLSLLVDLYLKF
                     QLVSSDQIEEIIDHAIQASSGSIKFCNQLDYEQTVDDF"
     gene            18828..19298
                     /locus_tag="IXT46_001838"
     CDS             18828..19298
                     /locus_tag="IXT46_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4947745.1"
                     /translation="MIKLVRIDHRLIHGQVALTWTNAISADCILVANDEILNDPIQKT
                     TLKLAAPHNVKVVIKSIQDSIDAINSGKTDKYKLFVVTKTISDAKRLANGVEQIKSVN
                     IGSVKETSGSSALTHTIFVTEEERAELKGMVSEGIEVFAQQVPTDKAIDLKKSL"
     gene            19322..20104
                     /locus_tag="IXT46_001839"
     CDS             19322..20104
                     /locus_tag="IXT46_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008724498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4947746.1"
                     /translation="MDSLLVQAILLGLLTAFIVIDWMTGTNNLSRPIVSSVFVGLIMG
                     DLKMGIMMGATLELAFIGAITIGAARPPDTVSGGILGTAFAIATGKGAEFALTLAFPI
                     AALFLLVDNLLTLLVLPMIARKADRYAEKGELKNVSKMHVLGFILVKSLPRALFVGFS
                     FYLGSPVMERILNAIPTFVQDGINIAAGIMPALGFAILLQMLLKKDVFVYFVIGFALF
                     SYLHVPILGIAIFGACLAYIIVNMETKAAMGSRGEEMVEDDF"
     gene            20094..20918
                     /locus_tag="IXT46_001840"
     CDS             20094..20918
                     /locus_tag="IXT46_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017867003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4947747.1"
                     /translation="MTSSGKALTKDDLTKICIRSCALEASWNFERQQHMGFAFAMMPA
                     LEKIYSGNEEEKQKAAQRHLEFFNTAPPLSTFIMGIVASMEEENAKNPDDFDTSTITS
                     IKTALMGPLAGIGDSMFWGTLLVIGIGVGASLAKEGNILGPFLFLLIFNVPNFLLRYF
                     GVMQGYNFGTKLLENIESSGVMKTLTHAASILGLMVIGGMSGSMVSIKVAGSIGQGDE
                     ATKIQSIIDGILPNLLSVLCVFLIYWMLKKGFKTTYVLFGIFIFGIIAAFFGFLTT"
     gene            20953..21951
                     /locus_tag="IXT46_001841"
     CDS             20953..21951
                     /locus_tag="IXT46_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011968302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4947748.1"
                     /translation="MLNYNAKEMKKKGKRIYGIREDVEKIAKQAYDSGISNIFFTASG
                     GSVAVMQPFEYVLMTESSIPVYSMTAAELVLMGHKQLNEKSLVILYSKSGDTKETIKA
                     AEYLKERNVPTVGIVSKEDTPLEALSTYAINYLDGRPQEMPLYFLIMSIMNLNGEFPE
                     YTRFADELKNLPTALNSVREQADEKGKKYAEEFKEDPYQIWIGSGNLWGITYSYSMCV
                     LEESQWLRTKSVSSPEFFHGTLELVEKGVCVTLLKTEGETRLLDARVEKFAVQYTDKF
                     NVFDTKDYELPGISDEFRKYFCAPVMWAALGRVSVHLEDIRNHSLDKRRYYRVVEY"
     gene            21968..22822
                     /locus_tag="IXT46_001842"
     CDS             21968..22822
                     /locus_tag="IXT46_001842"
                     /inference="COORDINATES: protein motif:HMM:NF012515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947749.1"
                     /translation="MTAYVIGFGDNVVDYYENLNQKFPGGNAVNFAVNAKKSGVKAYY
                     VGSLSSDPDGVLLQHAISSEGVDISFSEVIDEPTEQAHVTIKDGDREFIGGVRGSRLT
                     PALSAELIDLMKNSSLVHTSCHSRTETKIKELKKYDVKVSFDFSDLDKYRTHEYLSDV
                     CPSIYIAQFSVATDDQEEINRLISECKDFEVPYLLFTRGSKSPVFVDTRENKTYEGFI
                     RKVESPHDTMGAGDAYFAAFASNFVLSKREKSMIEHVIDCFHKGANLAYETLMIDGSF
                     GHATPINP"
     gene            complement(23396..24646)
                     /locus_tag="IXT46_001843"
                     /pseudo
     CDS             complement(23396..24646)
                     /locus_tag="IXT46_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            25163..25246
                     /locus_tag="IXT46_001844"
                     /pseudo
     CDS             25163..25246
                     /locus_tag="IXT46_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310545.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            25335..26746
                     /locus_tag="IXT46_001845"
     CDS             join(25335..25890,25890..26746)
                     /locus_tag="IXT46_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4947750.1"
                     /translation="MAKYPFELKLKIVKEYLSGVGEYRHLANKYGISSKSQVSDWVNA
                     YREYGEEGLLKKHQNQKYSVQFKLNALELYQTSEMSYREVASTLEMNNPALIANWMRN
                     FREAGIEGLSKEKGRPLTLTRKKENKKENTTTEERERIKALEKQVRSLQIENAFLKEL
                     RKLRKQEAQQRRKNQSHESSPASEDPFKLVELLETLKFPKATYMYWQKRFDRPNPDQE
                     IEEKMLEIRKEHKDYGCLRLKKELENQGIHVNKKKIQRLIKKLGIEVKSYTRKSRRYN
                     SYHGKVGTVAKNRIHRRFYTNICHQKITTDTTEFKYYEVDTTGVVRQKKLYLDPFMDF
                     YNSEILSYRISEKPNALAIMEGLEEAIQMTNDCPFRRTFHSDQGWAYQMNAYKNKLKQ
                     HKIFQSMSRKGNCLDNSPMENFFGLLKQEIFHGEVYRSLDELKTKIDQYIYYYNHKRI
                     KKKLNWRSPVQFREAVKTAV"
BASE COUNT         8891 a         4331 c         5375 g         8721 t
ORIGIN      
        1 tgtacaggtg tagataagtt ggtacttctt gatacggaag caactgaatc caactatcat
       61 gataagcatg acggatgaca gaatcaaacc cacaacattc gcaacgatgc gcttctccag
      121 ttaataagcc ggtaaataca ttggccatac ggccatgaac gcgctcttta ctaatggcat
      181 cttttgaaaa ggtaatatgg gaatctttga tgttcaaaat ttgtttgatg gaatgacttg
      241 tcttttcatc cgtacatttg atattcttag ttatggacat ttggttatcc tcctatgatt
      301 gtttttgccg atttaattat aggacaacca gatgtctttt tgttataaaa aaatatttgg
      361 cgtcactact cagtttgagt aacaaaacca aatattatag aaccggcttt ttcagttttt
      421 tcccttcaca aacaacatcg atgattttct cggcatgggt acgggtatca ttcattaatt
      481 ctgtatcggt tggatatttg atgttttgtg gagcacaagt ggcatccaaa atcaatgttc
      541 cggaattgaa atcgtcataa gaatcgttgt ccttatcgtc ttttttcttg tcgaagacga
      601 gtattttttc attgatttct atcaacgttg tttcgtccaa gcgtttccgg aaatagacca
      661 ttgtagagca tcgaaaggct tggcatcttg atagcccggc aaaccgatga agaactataa
      721 atacgggttt tcttgaattt gtaagaccgt ttcttcgtcg ctatagctat attccttttg
      781 aatcagtaga gctccgaagg tcatgcgaaa gggttttgcg acgtttcctt ttttttacga
      841 aaatttttag cgtagtcttt ttcaagttca gcccatggaa tgagctctgc tttttgaatc
      901 caacggttag acggattcat tttgagacct atcggttgat tgaaatcttc aaaagccaat
      961 tgaacggttg tttgtaattt atacatgaaa agcctccaaa attgagtggt actccacacc
     1021 attctgatgg tgcataagat aaaaaattaa agaagtgcct gtcatttgtc tgatttaagc
     1081 caaggtttga caaattttgg atattccaat taatactgta agcggttata tttaactcag
     1141 ggaggtagat gaatgtgaat acaaaagatt taaaactgtt agaaaccatt gtacgatcac
     1201 atgtgacaaa ctctcaacaa ttgaaatcat tagtacattt ttcgactagg cagataactt
     1261 actctataaa aaaaattaat gatgaattat cccttcatgg attgagtctg ataaagcgaa
     1321 gtaactcagg ggagtggtta tatgaagcca atgatcttca aaaacttttg atatacatga
     1381 atcaagcaat ggtttttaaa gaaggtgcga ttcctgaata tataaacgat gatttggctt
     1441 atagtgagat aagaagatat tcggaactgt tatttattct agccaacccc aaaaaagtga
     1501 caacccaaga aataatggcg tttattggta tcagtaaaaa tacggctaga aacgactttt
     1561 ctaaaataaa aaaagagttg ccaccagact acactttgat atttgatccc caaaatggct
     1621 atatgattga atcaagcatg gcaaagcttc atacattgct cttagaagtt ttcaattatt
     1681 tatttgaaag gcatgcaaca gttaaccgtt ttgagtcact cttttctgaa gaaagggaat
     1741 ttgttggttt ttttattcac acctacgaac aaacttttaa attgaaattt tctgataatt
     1801 cactaaccaa actttattat ttgataggtt tatcactttc tagttttaaa agaaggacga
     1861 aaggacagat tgattttagt tatgatttac aggaattaga tgagtttcaa atgattcgaa
     1921 gctgcattga tcaacattat caacatgctg agatagctat agattatgaa tggttgacgc
     1981 ttctgttttt atcattcaat acaatttcaa atgagtttga aattttagat tcaagaatct
     2041 atcaagtaat tatggagatg attaccttat ttcaaagtaa atcagctatt cggattagta
     2101 ataaagaaga gttgaccaat cgattgatga atcatttacg acctgcaatc tatcgaattc
     2161 gctacgaatt accatttgaa atagatgatt tagctgaaat tgttaaggaa aaccatgaag
     2221 ttagtgcggt acttaatttt gttaaagaat ccattgtacc tttggaagca tttttgcgta
     2281 agacgattcc tgaaactgaa ttatatttga tttctgttta tttttgttcg gagctattaa
     2341 attcttctat tatcgaaaca cctgttagaa aaaaggcaat cgtcgtatgt agcaatggat
     2401 tgattatggc caatgtaatg gcgaaaacat tgaaagaaat ttttccagat attcagtttg
     2461 ttgctagttc ttcggtcaga gagatggata agtttgtcga agatgttgat ttgattttta
     2521 gcaatcaacc attgaaaagt gaaattccat tatatattat acaaccgatt atgaacgaag
     2581 aagaaaaaaa ccgcttgcgg aaccgtgtac tcattgattt ttctacgaat aatatcagca
     2641 aagagactag gaaccttact gaaattatta agcgttactc tgctgttcaa aatgaagaaa
     2701 gtctacaaac tgatattgag agatttttaa ttaattatgc aaattcacta atatatctag
     2761 atcgtcaaag taaacaggca caaaagatat cttttgtgga attgcttgtt tctgaaggga
     2821 ttattcttgt atctacgaaa caacttactt ggcagaacgc gatggaattg tcttgtcagc
     2881 ctttattaaa ggagcaggta attaatcaga actatcagac tattttaatg agtcaaatgg
     2941 cggatgaaga ggcttattat tttcttaata atcgtattgc tattccacat tcatcgccag
     3001 aaaatggggt aattaagggc ggttgctcgt tacttatatc agttgatcca attatttttc
     3061 ctggaaatag gcctatccat tttatttccc cttttgcaat tggaaagaag gaaaattatt
     3121 tacttgcgat taaccaatta ctacaacttt ctaaggacga ggaatatcag caagaaatac
     3181 ttctttgcac gacggaagat gaagtgagaa aaaaaataaa aaatttttta aggaggaagc
     3241 aatatgtcaa taacgaattt tcctgaatta accatcattt taagaggata tagttttgaa
     3301 gaggcgatgt ttgtcatgga agaattggct gcgatgaaca cttcggtagg aattgaagta
     3361 acaaccaata atgatgactt tgcacgtatc atcacagaag gcaacaaaaa atttgggcaa
     3421 caattattga ttggtgcagg gacagtttta acattttcac aagcagatca agcaattgct
     3481 ggtggtgcga aatttttatt aggaccaaaa aaattttcaa caccaatttt ttcgttggct
     3541 aaagaacgtg gggtggtaac tgtgccatca gcttttacgc catcggaaat tcaagttatg
     3601 tttgatgaag gtgccgatat tgtaaaggtt tttccagcag tcactgtagg gccaacctac
     3661 tttaaacaac tggccggtcc ttttggtata cggcctttaa tggcagttgg aggagtgacg
     3721 attgataata ttgcggcttt taaaaaagca ggagttgtgt actttggggt aggatcaagc
     3781 atgtttcaaa aagctgatat acaaaaccgc aatgggcaag ctattcgaaa atcaattcaa
     3841 tcatatttag ataaactagc tgaagcagga agtgaagaag atgagtctca ttaaattaga
     3901 agaaaaaaat attttgttaa atcaaagttt ttcaaaccaa gaagaatact ttcaaaagat
     3961 tacaaagaaa ctgatgacgg aaaacatggt aaaggaggga tatctcgagt caatcactaa
     4021 gagagaaaca acttatccaa cggggctata tattggggaa cgctcaatcg caattccaca
     4081 tacagattat cagttatcaa atgttaccgc tattttagta tccgttctta aagatagttt
     4141 gcattttcag cgaatggatg atcccgaaga aatggtttca gtgaatgtta ttattcacct
     4201 tttattcgat agtcccgata agcaaccgca attattgaag gagttgatga gtaaagttac
     4261 caatcaggat ttcttacaag caattatgga agcaaagagt aaaacagaag ttttaactgc
     4321 atttaatcaa taaattggag ggaaatacaa tgagtaaaaa aacaattatc gtcgcatgtg
     4381 catcatcaat gattacatct acaatggcag ctaataaaat tcggaaaata gcaaaaacaa
     4441 atggattacc agaacctcga attttgcaac taaaattttc agaagttgca ggtgctttag
     4501 aatcaaatca agttgacttt atcgttccta cagggaaatt acaagaaaat gtaaccaaag
     4561 gaattaaagt tatacctgga acaccatttg ttactggagt gaatgaagaa aaatctgaat
     4621 ctttggtgtt agaagcattg aaagagcttg actaggaggg tgaaaaatga atattgtcat
     4681 tgatgcgtta aactggatct caagtttggg tccgatgatt atgatgccta tcattatctt
     4741 gattttagga ttatttttta gaattaagct aaatacatta ctaaaatcag cgttgactgt
     4801 ggggattggt tttgcgggtg taaatattat tattaattgg tttatttcac aggtaggtcc
     4861 atctgttcag ttaatggtca aaaattgggg tattcaaaca agtattatgg atgtcggctg
     4921 gccagctcgt gcagcagcca cttggtcttt tcctctagca gcagttatgg tatttattat
     4981 tttgggtatt aatgtgttga tgctgatttt taaaaagacc aatacagtaa tggtcgattt
     5041 ctggagttat aatcactata tttttgtagc tgctttggtt tattatgcaa cggataaaaa
     5101 tattatattg gcggtaatct tcggggcgat tgatgcaatt attagtttta aactcgctga
     5161 ttggacaacg ccgttagtag aggattactt tgaactagaa ggggttaatt tcccgactgc
     5221 gaactcagtt ggttgggcac ccttggcttg gctacttaac aaattgtggg accgcattcc
     5281 tggattaaat aaggtagatg ctcgtcctga aaaaattcaa gagcggtttg gttttgttgg
     5341 tgagcctatg tttatgggat ttgtcatcgg cttggttatt gggttattag caaaagaacc
     5401 tgttgataag gtattgatag tgggaatgag tacttctgca acaatggttc taacacctaa
     5461 aatgatgcaa attttaatgg aaggattatt accctttgct aattctgtta agaaattctt
     5521 gaatgtaaaa tttccaggaa acaattttac aatgggtgtg gatgctgcgt tgacagttgc
     5581 taattcaagt gccattgcta cgggtattat catggttccg attaccttag tgttggctgc
     5641 tattttacca ggtaacaaac tcttacctat ttcagatatt gcctaccaag caatgtggct
     5701 atctgcatgg ccggtcgcct tttcaaaagg aaatattatt cgcggaatac tttccaccac
     5761 gattataaca gcttgtgtgc ttttaattgc tactagttta gccggcatac atacacaatt
     5821 agctttggct gggggattcc aattaccagc aggaatgaca caaatatcta ccgaagatgc
     5881 aggtacacac attattggtt tcattttaat gaagattgct gagtttattt caaatatttt
     5941 ctaatattca ggagggcata cagtgaaaat ttcaaaaatt acagtctata aagtaaaacc
     6001 aagatggatt tttgtcaaaa tatctacaga tgaaggtatt gaaggctggg gtgaaatgat
     6061 ttctggaact aagactgaaa cagttgtggc aggagcttat gagataggaa atcgattctt
     6121 agttggtcaa aacccatttg caattgaacg tctgtttcag gaaatgcatc gttcattttt
     6181 ccgaggtggt cctattaatg gaacgattgt ctctggactt gaaatggctt tatgggatat
     6241 taaagggaaa gccttaaatg ttccagttta tgaattacta ggtggagcag cccgtgataa
     6301 aatcaaagta tattcttgga ttggtggaga tcgtccttct gaagtagtag agcaggcaca
     6361 agatcgagta gatcgtgggt ttaccgccgt gaaaatgaac gcgacagaag aattacacta
     6421 cattgattct tatgaaaaag tagctgaagt agtggaacgt gttgcttcaa ttagagaacg
     6481 ttttggagat acattgagca ttggtgtcga ttttcatggt cgtgttcaca aaccaatggc
     6541 taaggtttta gcaaaagcac tggaacccta tcatccaatg ttcttagaag aagtggtttt
     6601 gccggagaat gaagaacatt tcagtgaagt agccaatgca gttgctgtac cactagcaac
     6661 gggtgaacgt ttgtatacaa gatggcaatt taaatcaatt cttcaacagg gagcgattga
     6721 tatcattcaa ccagatgtag ctttatgtgg agggatttta gaaacaagaa aaattgctgc
     6781 aatggctgaa gcttatgata tagcagttgc cccccatgca ccatatggac cgattgcgtt
     6841 agcagctaca ttacaagttg attcttgtac acctaatgtg tttattcaag aacaaagctt
     6901 aggtattcat tacaacaaag ggtttgattt gttagatttt gtaaagaata aagagatatt
     6961 ccaatacaaa gatggcttcg tagatcttcc gacaaaacca ggtttagggt tagaaatgga
     7021 cgaagatcga gtgaaagaaa ttgcacaaga aggtttagtt tggaccaatc ctaagtggaa
     7081 aaattatgat ggtacaatcg ctgaatggta ggagatgagt gcatgatcaa tacggttaca
     7141 ggcccaatcg aagctgagtc tttgggtaca acatttattc atgaacattt atatgtcatt
     7201 cctaatgagt taagaaagta tgaagattat accttggatg atatttatca tagtattgcg
     7261 gaagttatgg cttttaaaca agctggtgga aaaactatcg ttgatttgac accaattaat
     7321 tatggacgaa atccgttagc tttgaaaatg atatctgaag ctaccggagt gaatgtagca
     7381 tttgttacgg gattccataa ggaagagttt cagccaaaat ggttgacaac gctcaatgat
     7441 gatgagatct ttgagttgct ttattccgaa ataactcacg gagtcacttc acaaaacctt
     7501 ttgccaggag caatgaaagt aggtacgagt aaaaatgagg ttacattggc tgaacaacga
     7561 atactagcca tagccggtca agtacaaaaa aaaacaggga ttcccattat tacgcattgt
     7621 gatgggggga cgatgggact ggagcaaatt aattgtttaa caaaaaacgg tgcgaaagca
     7681 agtaatattt gtttgagtca tgtagattta actaaagatt ttcactattt agctcaaatc
     7741 tgtgaaacgg gagcaagtat ttgtatggat catattggcc gagagttggc gaatcatgat
     7801 gcagaccgcg tccaactaat taaacgactg gttgatgcgg gttatgaaaa tcagatttgt
     7861 ctttcaggtg atatgggacg aaaaaaatat ttgccaactt atggaggaac gcctgggctt
     7921 acctatattt taacaagttt gaaagaagaa ctattaaaag taatgagtga accaactttt
     7981 aataaaatga ttgagatgaa tccaattaat atactgagta agtgaagtca attgaatcat
     8041 tcagaagaac taatgaaatt agttgctttc gcagggttaa ttcttctctc tgggtttgga
     8101 aaagagggct tagcttcgga ttccctagtt aaactagggg ttttatcagg ttattgtact
     8161 gattataagt acctgaatta ttcatgaaat actttttccg tcgttttata ggcagttggg
     8221 tcaataaaaa gatcagaaaa acgaacgaga gactctcata acgtgccact aaataaaaat
     8281 cgtacgttat tttaaaaaat gggttgattc taggcagtac tttgtcggtc tatttttaga
     8341 aaaagaggtt ctttgtcaaa catacatgaa ttcgcaagct cattcaccct gaaggatgaa
     8401 aggcagaaac tgtagtatac taatggtgga aaggaaaaaa agccgccagc aatttggaaa
     8461 agaacgttat gtcgattgtc aaactggctt gctttatttc tcgagaaccc tgaaatatag
     8521 ccaatgagca tgtgtataaa aaattgattt tatatgaaat aaagcactcc tttcctaaaa
     8581 ttattggaaa ggagtgcgtt ttttatggaa attatttagg ttctttgtca attgctattg
     8641 ttttgctcaa atcgtatgtt aggaaatgct tcggcatttc cttttttgcg ttattaaatg
     8701 atttcacaga tgttctgttg aatcaggaca cgcatccgga gatgacgaaa agtccgaaat
     8761 ccaaaagcaa ttcttttgat tactttgatg aggttattct ttccctccaa ttttccgttt
     8821 gaatagggat attttaagga gtttgtgatt gcttctgtgt gctttttcag ataacaaatt
     8881 gcctttttaa acccatcatt caaggaatgt ggcaatgatt caatgagatt gaaaaattca
     8941 gtaaaatctt ttgcatcaaa agcagctaat aactcttgat agacttcata gctttgtcgt
     9001 agttggttat ctatagagag taggtaatca agcacctccg actccgtcat gtatttccct
     9061 tggaagaggg gaaattgctt aaaagggttc tgttgcgaag tttgaaaatc aaacgcgccc
     9121 tctctgaact ccaaatatct taggctgtta ttcccattaa taccttgatt tcagtagaca
     9181 ccgaaaagcc gaagagcgtt ccatttcttc ggttcttttt atatattcct cgaatggtct
     9241 ccatgccctt aatcgtggaa gaggctgtac ggagactttg ataaaattta tttcgtcgtt
     9301 taataggtcg atggtcttgt tctattaaat tgttaagata cttcacagtt cggtgctctg
     9361 tcttagtata taaacccaca ctctgtaact ttctaaaggc ggagccaaga gaaggtgctt
     9421 tatcggtcac aattgctttc ggctcaccaa actgtttatg gagtcgtttt aagaaagcat
     9481 aggctgcttg cgtatcccgt ttctttcgta accagatatc taaggttaag ccgtccgcat
     9541 caattgcacg ataaagataa tgccaacgtc ccttaatttt gatataggtt tcgtccattt
     9601 tccatgaata gaaggattgt ctatttttct tcttccaaag ataatagagg actttgctgt
     9661 actcttgcac ccaacgataa atcgtagtat gacaaacatt tattccacga tcatataaca
     9721 attcctgaac ttcacgatag cttagattgt aacgcaggta gtaaccaaca gcgacaataa
     9781 tgacgtcttt tttgaattgt ttgcctttaa aatgattcat tactctgtcc tctctgtctt
     9841 ttttctcaat tttacactaa aatagatttt ttggaaaact ttgcaacaga accatttcta
     9901 atatgaaagc aattatcaac agtaaggatt acgaaggata taaagccaaa catccagaag
     9961 cgaaaccatt taaataccca caagaaatga agcgagcatg gcgtaaaatg ttagatgatg
    10021 agttgattcc acttgaaaat gaattgaggt aaatgagaag agttaagaaa attgtacgat
    10081 tcaaagatag tagtaaagtg gaagtgtaga aaatagggat agatgtcttt tatttgttca
    10141 cattttataa cgaagtattt aagacagcta ttgaataatg tttcctccac ctttttcatt
    10201 catttacccc accccgttgt tatatgaccg tgtttcgaga gaaaccaata aaaagcatag
    10261 gctaactagg ggttcctttt tcttttgatt ttttggaatc cgcttaagtg aaatgtatct
    10321 gaaatgaaac agagataaag tgattttttg ctgtaatgac aaggttttag ctgtttcaga
    10381 taccatgtaa cccaaaatag tttattgaga aaataggaga gtatttgata ctaactagta
    10441 ggaaaaaatg agataaaaag taaatggaat catttcaggt aatctcaaat aaaaaatata
    10501 caggcctgtg gcactttacc tacgggactg tatatttttt actctcagcg ggcttgtttt
    10561 gactccgtgt ttgactccgt cgtattgatt ttaaatgata ttcgatgacc aattaatagg
    10621 tcgtttttga aatttttgtc tctatatgac tcagtttgat aattattgat agatcgattt
    10681 gggtctatat cgaacaaggg aagattgcaa aagtcgaagc ttaaaggatt gatattaaag
    10741 gattaagagg taaaaaggta tccccataat atcctctgac tccgtttttg acctcgctta
    10801 tcatccgttc atgtaagaat caaataattc gactgtttca ttttgccgat tttttgatac
    10861 tttaatataa atgtccatga ttgttttaga agaagaatgt cctagcctat cttgtacatc
    10921 ttttacttga gcacctgctt caaagagaag ggtagcatga gtctttctga agccatggac
    10981 tttgattatc ttcatatctg ggaacttccg tgctacttta tccatgacat ggttagggta
    11041 gcctttgtaa aggaagtccc tttttttatt ccctttgata gtgctgatta caggtatatc
    11101 atctatatta tctatccgaa tccctctaga aaggttcttt tatgttacag aacgtttcca
    11161 ttttttagaa tacgtaaggt tccattatca attgaaatta ctccctttga tttgtctgtt
    11221 tttgtaggat taatacatag agagccctcg gatagttcta ctaacgtttt gttgaagcag
    11281 atagtttgat tatcgaaatc tatgtctcta catgtcagtc cgagtatttc tccttttcgt
    11341 tcccctgtat aagaagctat tctaaagaat actaaagcac gctcatcttt taacttatgc
    11401 aaacattcaa aaaacagata tttcacatat atctaaaatt cggagattga aagaatgaat
    11461 ttatctaaga attttcacta atgttgcgaa tataatatca gaaaatttcg aaataaattt
    11521 tgttaaaaat tagaaaaatc cgaatactta gtagtggata aatttttttc aggaatagta
    11581 cgttttatta aaatgaaaac taatccgaca tcaacttttt tatcgaagca aacatcaagc
    11641 ggtaaaaaga cctctttagt ttgaaaagtg ttgctttcat attgatttaa attttggtta
    11701 agtaggtaaa ttaagaaatg atcagtgtaa gtatttcctg atttagcgca ccttgttcac
    11761 tttgaaaata caggtttttg atggacagat tttgcttcaa atgtttaaag aacatgccac
    11821 tgtacttggt acaggtcggc gcccccattt ggagttgcgt cagatcgagt cgtgacgatt
    11881 cattttgtac aaattagaat ttaaaattga atacatgacg cgcacatttt cccagagagc
    11941 catattctgt aattaatcac agcaattagt gattatgcac aatctaaaaa actgatttat
    12001 aataaaaata ttattcaaat aaataataat aactgcccgc atgatgttga cagttacaat
    12061 agcacataga tagactggca aagatggttc ttaatctttc actttggtca gaattcttgg
    12121 gttatccttc cagtgaaagt cagcagaaaa tccttaatgc ttacaaataa tttttgcgaa
    12181 ataggtttta ttggtaaagg actcaatcat gaatatgaat tacttttatc tggtaaattt
    12241 ggaaaaattt tgcaaagaaa taaaaattag acaaatttgc tacacataat caaagattaa
    12301 aaaagttttt aaaatatagt tgtttgaatg gggatatgaa ttagagaaaa ttggttgatt
    12361 caacgggtgc tatcattttt gatagcgtca tatgtgaagt aagcacacct aatgaaaaag
    12421 gttcaggctt gctttgaaga cttattaaca actatgtcga ctatccttga cttagggtag
    12481 aggagtacct ccacacacct taattagatg ataatgtttg gactgtaggc tacttagcgg
    12541 attaagataa agaggaagta gaaaaagagc cttgcggaaa gacactttat ctgttatccg
    12601 cgaggctctt tatacattta agcatattta aaaattattt ggaaacagta ctttcaaact
    12661 ttgtcttata agcagggtac ttagatattt catattcaaa cggtttctga tttttagcaa
    12721 atccaatact tgtaaagaca aagactggct catttttttc taaatcaaga taaaggtttt
    12781 ctaaatctgt tggcggtgta acttcaattg agcgtttggc ataagctaat ctaattcccc
    12841 tactttctaa tactgagaac agggattctt tggcaaaatc atgttcaaca atttcaggta
    12901 aaacagatag gggaatgcaa ctttttgcaa tacaagttgg atagtcatcg atgtatcgaa
    12961 ttctttccaa gacaagcact aaagtattct gctcaatctc caaacattca ctaattgttg
    13021 aatcagcagg tatgatggtt tgttggataa tcttagaact gattttcttt ccttgctgaa
    13081 ccgcatcttg gaagaatccg ataaaagagt cgagttcgtg gtcaacatat ttttctgaag
    13141 ctggtttcac tagatacccg cgaccttcat ttttagaaat aattccttcg tcttctaaag
    13201 aagctaaagc tttccgaatt gttggacgac tcaccgaaaa ttcctgggcc aaatctcttt
    13261 ccgaaggcaa taattcagat ttccgatcag tggtgatata cacttttcga atttgttctt
    13321 ttactttgtc aaaaatcata gtaatccatc cttttaccaa ggtattaaca ttatattacc
    13381 atttttttga cttaatatcc cagattttcc ttcaattaat tccttcgccg ctaattgacc
    13441 ccacaaatag ccaatatatc ggtcataaaa agttggagat gatccacgct gaagatacgc
    13501 aagatttaag tatttggttt cttttggtaa atttttggta ataaattcaa tgattttttg
    13561 tttgttagat ataccttctg gtaaaagcaa tataggcgag tagaactccg actcaaattt
    13621 tttacatatt aagtgtaagt attccttgtc gtctctctca acccaataag tattatttgc
    13681 aatggaagcg tactctggaa gagcaaagca gcctcggccc atgacttcca ttataataat
    13741 acgatcatga gcattagcag tagaagttaa atcatcgatt gatcggatta tagtgtttaa
    13801 ggcgctatcg aagccaagtg tataatcggt attggggaaa tcgttatcaa tagtccctgg
    13861 gatgacagat acttgtaatt ctgattcatt tttcaatagt tcagctcctt tcaaggaacc
    13921 gttacctcca ataacaatta agttgtcgat ctccatctta tttaggtttt caataataat
    13981 tttccgactt tcgagatctc tcattttctc aaatctggct gttccaataa gtgttccagc
    14041 tttgaatacc tcaacttctt ttagagaaac tgaggcaata cattccttaa atattccggc
    14101 ataaccattc ttaaaaaaga ctacttccga atctggttcg ctatcaattg ttttttttat
    14161 tgctaataaa gctgaattca ttccgggaga gtcgccacca ctacagataa ctgcgatttt
    14221 cattttagat cctcctaaaa aaggtgactg cgattctatt ctcccattag agaaaatgaa
    14281 gcaatcaaat gggcaatgga gtcgcggtca cctttttcat atttttatga ttagtattcc
    14341 atttgcttat aataacggcg agtagttaaa gggtggttac gttcttcttc tagaaaagca
    14401 ctaattcgtt caaagacagt agctaagacg actggggaaa taatttttcg cgtgtcttcc
    14461 gaaatgccag gtaagtcata gtcctttgta tcaaccgtta cgtgaacatc tgtaaactta
    14521 ggaacgaaat tcttcacgcg ttctgtgaga ggtcgagaat catcttctcc ttctgtaatg
    14581 atgacactta cacccgcttc aattaattca agagttccat ggaagaagtc tgctgcatga
    14641 acaggacgag tcttaatcca ttgcatctct tctaaaatac acatgccata gtaatatgct
    14701 tccgcaaagc tatcaccagc accggttaaa atatgatatg aagtatcttt gtgttttttt
    14761 gcaaaagatt ttgccattgg ttccgcttgc tctttagcgt gcactaaggc ttcaggtatt
    14821 ttttttaaat cctcaatata ggtattgtat tgattgatat cgatttcatt tctttgtttc
    14881 attaagaaga gagcaatcag cagtccttga aggtaataat tttctgaaga tgtatcatct
    14941 aaaacgtcgt tatagataga atatgttgca gctttttcta ggggcgtttt aggacttcct
    15001 accaaagcta atgttttgac gttcatttca ttacagtatt cgactaactc aagtgtttct
    15061 tttgttgtac cagataaaga tgggataaca accaaagatt tgttagaaaa tgttttattg
    15121 ggatgaatca taaattcggc agcgataaca cgatgaaaag ggaaagtgct acgagttctc
    15181 gcgaattcga ttgttgaatc aaaaagaata ccaactcctc cagacccaat aaagtaaatt
    15241 tcttctaagt cagatgcgat ggattctaaa atattggaaa tttgttcatt tgttgcaacg
    15301 gcaccagctt gagtctttaa aaatctttct tgatcaaaat taaacataaa aatctctcct
    15361 ttgattacca atggtaatat tttgtttgca taaataaaat accacaggta ataaaaagtg
    15421 tcaaatattt tttaggaaaa ataccatagg tattgttaaa gtggaaagat gtttataaag
    15481 aatattgaat tttatagtga aaatcattta ttattaagta aaggaggtgg gttcatttga
    15541 aaacgaaaat tttaaaagaa ttaaatgatc tacttaacag ctatgatttt ccacaatatt
    15601 ttccagaaga atgtaacgcg caatatattg cccaaaaatt tcaaataaaa agaaatacgg
    15661 ctagtaagca tctaaacgaa ctaatggaac agaaaaaagt tgtgaaaatc aatggtcgtc
    15721 ctgttctttt ttttccagtc catacaattg aacggtatat atcacattca ttagatagtt
    15781 ttgagttttc ttcaattgat tcgtttagag aaaaaatttc aaagaaaaaa gcagatcatt
    15841 tttttgatga tttaattggt gcaaaacaaa gtttaaaaga agcggttcaa caagggatat
    15901 cagcaatgaa atatccaggt ggattaccaa taatgtattt tggatcgtcc ggagttggga
    15961 agagttactt agtggaaaaa ctagctgagt attgccgaca aactggtatt attcatgaga
    16021 atgctccgtt catcgagtta aactgcgctc agtattttaa taatccagag ttattaacaa
    16081 gtcagttgtt tggccatatg aagggatcgt ttaccggcgc cgattctgac catattggta
    16141 taatagaagc agcagacggt ggaatcgtct ttcttgacga aattcatcgt ttaccaccag
    16201 aaggacaaga gaaacttttt attcatatgg ataaaggcgt ttttcgaaga gttggagata
    16261 gtggtccttg gcgtttatca catgttagat atatttttgc gacaacggaa caggaagaaa
    16321 atttttttct agaaactttt cgacgaagaa ttccgattgt ttgtactttg cctaattacc
    16381 aagatagaga aattagcgaa cgaaaagaga ttgtcttcca tttattagag aaagagtcta
    16441 ctctgatcaa taaagaaata ttagtttctg aagccgccct tagtttcctg attcgcttag
    16501 atttgtatgg aaacattggt gagctggatg gactaataaa acaaactatt gcgaataaac
    16561 tatttagtgg aagcaataaa aaatatatcg aaattcatat ttctgattta cctagcaggt
    16621 acttgctaac agaaaatatt gagttaaaaa accaaattgc gagccaacgg ttctatatct
    16681 ttagtaatgg taactatgtt catgattgtg acgagacttc aactgtaact acaaatttac
    16741 gaggtttgat tcatcgtgtt tctaaatatt attcagagtg tcatgatgtg aatagaaata
    16801 gtgaagagtt tcgacgtttt gtgaaggacc aaatggcaga atttaatgat cgttttattt
    16861 accaaaaaaa ttcagaagtc ttagttaagt attatttacc ggaaatccaa aatattgttc
    16921 aaaaaatctc tcccagtctt tttgttcacc tttctggcaa tacggtccaa gctatagcta
    16981 cctatctcgc tattagggat caatgggggt atgggaaaga gaatgcttca gcgaatgaaa
    17041 ttgaaaagtt atatgaaaac ctaaagtgta actatttgac ggatttaaat gtattcttac
    17101 tgatcttcga gaacgccctg gatacaacat tgactatttg ggataaactg tatatcagtt
    17161 tgtgtgttat tagtgagacc ggaaatgaag cgaaagacat taacgcaatt attttagccc
    17221 atggatatgc gacagctagt agtattgcta atgttgccaa tcgtttggtt aatcagtttg
    17281 tcatagattc tattgatatg cctctagata tcagctttag tgaagtaatt gacagattac
    17341 ttcactatat agagtatcga aagcctaaag atggactagt gattttcgtt gatatgggaa
    17401 gtttagctca aattaagact gaaattgaac aagtaatcga agttccaaca atgattatta
    17461 ataatgttac aaccgaaatg gctattgaaa ccgcacaact gattcaaagt acgagtgata
    17521 tccaaaaggt tgtaaaaaaa ttgccgtatt ctcagtttga aaagcaagtt ctatatccca
    17581 tcaaaattag aaaacgtaca atcgttgttt cctgcaatac tggtttgggt acctccataa
    17641 aaattaaaga aatgatggaa aataatttgt cgaaagactt gggcattgaa tttctgccat
    17701 acgaaaatga aactcttaga gatactcagc aattagagtt tctcattaaa acaaaggata
    17761 tcattgccat tatcggaaca gatgatccgc gtgtgtcgaa cattccctat atttctcttg
    17821 aagaattatt tgatggtgaa attggcaaac tctataaagt tcttttgaga gtctatggaa
    17881 aagagattgc tgaggcaatt aatcaaaata ttgttaaaaa tagctcatta aaccgcttga
    17941 ttgacagtct tactatttta gatgccgaaa aagttgtcaa tcaaattgag gaaagtttaa
    18001 aagattatca aatgagggtg gggaaaacgt tatcatcatt gtccaaaatt aatctttatg
    18061 ttcatatcag ctgtatgatt gagcgactaa ttcgtaatca gggagtaagt agttatccag
    18121 caatagatca gtttcttaag cgatacgaaa ctgaggttgc ttctattcaa aaggcactta
    18181 gtaagattga gaaactttat aatattaaga ttcctatgga agagattgca tatgtgtgca
    18241 acatcattgt aagttattga taaaataaag tgacactatt cacagcgatg gaaatagtgt
    18301 cactttattt tttgtacgcc ctttcattta agtggtgaca gtaattggca cagtatttgc
    18361 taataacaaa gcgaaaggag ttcgggtatg agacaaatat tatgtatgag ccacggtcct
    18421 ctagcaaaag gaatgattga aactttgagt attatcgtag gagatttgga taatattgat
    18481 tttcgatgtg cctatgtcga tggaaataat gacgtagaaa tgatcatcga tgattatcta
    18541 aaggaatcta tgggaaatga gacgattgtt gtaaccgaca tttttggtgg aagcattaat
    18601 aatgagtggc taagacggtt gccagatctt tctaaagtct atttgatttc tggaatgaat
    18661 ttaagtcttt tagtggattt atatttaaaa ttccaattag tttcatctga tcagattgaa
    18721 gaaattattg atcatgcaat tcaagcatct tctggttcga ttaagttttg taatcagcta
    18781 gattatgagc aaacggttga tgacttttaa ataaaggagg gaagagaatg attaaattag
    18841 tgaggatcga tcatcgtttg atacacggtc aagttgcttt aacttggacg aacgcaatca
    18901 gtgcggattg cattttagta gcgaacgatg aaattttgaa tgatccaatt caaaagacaa
    18961 ctttgaaatt agccgcacca cataacgtga aggttgttat caaatcaatt caagattcga
    19021 ttgatgcaat taatagtggg aagacagata aatacaaact atttgtagtt accaaaacca
    19081 tttccgatgc taaacggttg gcaaatgggg ttgaacaaat taaatctgta aatatcggta
    19141 gtgttaagga aactagtggc agtagcgctt tgacgcatac aatttttgta acagaagagg
    19201 aacgagcaga acttaaagga atggtctcag agggcattga agtgttcgct caacaagttc
    19261 caacagataa ggcaatagat ttaaaaaaat ctttgtaata aaaaaataag ggggtaattt
    19321 catggatagt ctcttagtac aagcaatttt gcttggtctc ttgactgcgt tcatcgtaat
    19381 tgactggatg acaggtacga ataacttatc aagaccaatc gtatcttccg tctttgttgg
    19441 tttaattatg ggcgatctta agatggggat tatgatgggg gcaacactgg agttagcatt
    19501 tatcggagca ataacaatcg gagcggcacg tccgcctgat acggtatctg gtgggatttt
    19561 agggactgcg tttgctattg caactggcaa gggagcagaa tttgcgttga ccttggcatt
    19621 cccaatcgct gcgctattct tattagttga taatctacta acattgcttg ttctaccaat
    19681 gattgctaga aaggcagata gatatgctga aaagggcgaa ctaaaaaatg tgtcgaaaat
    19741 gcatgtttta ggttttatct tagtaaaaag tttaccacgg gctttatttg tcggattctc
    19801 attttactta ggaagtcctg ttatggaacg aatcttaaat gctattccaa cttttgtcca
    19861 agatgggatt aacattgctg caggcattat gccagcacta ggttttgcta ttttattgca
    19921 aatgcttctt aagaaagatg tctttgtata tttcgtaatt ggttttgcac tctttagcta
    19981 cttacatgtg ccgattctgg ggattgcaat cttcggcgca tgtctagctt atattatagt
    20041 aaacatggaa accaaagctg caatgggttc aagaggggag gagatggttg aagatgactt
    20101 ctagtgggaa agctttaact aaagatgatt taacaaaaat ttgtattcgg tcatgtgcat
    20161 tagaagcatc atggaatttt gagcgccaac aacatatggg ctttgctttt gctatgatgc
    20221 cagcgttaga aaaaatttat agtggcaatg aagaagaaaa gcaaaaagca gctcaaagac
    20281 atctagagtt ttttaacaca gctccgccat tatcaacatt cataatggga attgtggctt
    20341 ctatggaaga agaaaatgcc aaaaatcctg atgactttga tacttctaca atcacttcta
    20401 ttaaaactgc attgatggga ccattagctg gtattggtga ttcaatgttt tggggtacct
    20461 tattagttat cggtatcggt gtaggtgctt cattagcaaa agaaggcaat attttgggtc
    20521 catttttatt tttactaatc ttcaatgtcc ctaattttct tctccgttac tttggagtta
    20581 tgcagggata taactttggt acaaagctat tagagaacat tgaatcctct ggcgtcatga
    20641 aaacgttgac tcatgctgcc tcaattttgg gtcttatggt aattgggggc atgtctggaa
    20701 gtatggtatc aatcaaagta gctggttcta ttggacaagg tgatgaagca acaaaaattc
    20761 aaagtatcat tgatggtatt ttaccaaatc tgctgtcagt attatgtgta tttctgattt
    20821 actggatgct taaaaaaggc tttaaaacaa cttacgtgtt attcggaatc tttatctttg
    20881 gtatcatagc agccttcttc ggatttttga caacttaatt gaataatcta aataattgta
    20941 aggagagaac taatgttaaa ctataatgca aaagaaatga aaaaaaaagg caaacggatt
    21001 tacggtattc gtgaagatgt agaaaaaatt gcaaagcaag cttatgattc tggaattagt
    21061 aatattttct ttactgcttc tggtggatcg gtagccgtaa tgcaaccatt tgagtatgta
    21121 ttgatgactg aatcaagtat tcctgtttac tctatgactg cagctgagct tgtcttaatg
    21181 ggacataaac agttgaatga aaaatcttta gtaatcttat actcaaaatc tggagatacg
    21241 aaagaaacta ttaaggcagc tgaatattta aaagaacgaa acgtgccaac cgttggtatt
    21301 gtaagtaaag aagatacacc gttagaggct ctatcaactt atgcaatcaa ttacctagac
    21361 ggccgccctc aagaaatgcc actttatttc ttaattatgt ctatcatgaa tttgaatggg
    21421 gaatttcctg aatacactcg ttttgctgat gaactgaaaa acttaccaac ggctctgaat
    21481 tcagttagag aacaggctga tgaaaaaggg aagaagtatg ccgaagaatt taaagaagat
    21541 ccttatcaaa tttggattgg tagcgggaat ttatggggaa tcacctactc ttattcaatg
    21601 tgtgtgcttg aggaatctca atggttgcgt acaaagtctg tctcatcacc agagtttttc
    21661 catggtaccc tcgagttagt cgaaaaagga gtttgtgtaa cacttttgaa aactgagggg
    21721 gaaacacggc ttttagatgc tcgagttgaa aaatttgcgg tccaatatac agataaattt
    21781 aatgtttttg atactaagga ttatgagcta ccaggtatta gtgacgaatt tcgaaagtac
    21841 ttttgtgctc cagttatgtg ggcagcccta ggtcgcgtca gtgttcatct tgaagatatt
    21901 cggaaccact ctttggataa acgtcgttat taccgagtag ttgaatacta aaagtaggtg
    21961 attaattatg acagcgtatg tgattggatt tggcgataat gttgttgatt actatgagaa
    22021 tttgaatcaa aaatttccag ggggaaatgc agttaatttt gctgtgaatg caaaaaagag
    22081 tggtgttaaa gcatactatg tcggtagtct atcatctgat cctgatggcg tgttattaca
    22141 acacgccatc agttctgaag gtgttgatat ctctttctcg gaagttattg acgagcctac
    22201 tgagcaagca catgtaacta ttaaagatgg agatagggag tttataggtg gcgtgcgtgg
    22261 ctcccgattg acacctgctc tctcagcaga acttattgat ttgatgaaga acagttcatt
    22321 agttcatact agttgccata gtcgaacaga aacaaaaatt aaagaattaa aaaaatatga
    22381 tgttaaagtt tcttttgatt tttctgactt agataaatat agaacgcatg aatacttgtc
    22441 agatgtttgt ccgtcaattt atattgcaca gttttcagtc gctacagatg atcaagagga
    22501 aattaatcgc ttaattagtg aatgcaagga ctttgaggtt ccgtatcttc tttttacgcg
    22561 tggtagtaag agccctgttt ttgttgacac tcgagagaat aagacttatg aaggattcat
    22621 tcgcaaagtt gagtcacctc atgatacaat gggcgcaggt gatgcatact ttgcagcttt
    22681 tgcaagtaat tttgtcttat ctaaacgtga aaaatcaatg atagaacatg ttattgattg
    22741 ttttcacaaa ggtgcaaacc ttgcatatga aacattgatg attgatggct cctttggtca
    22801 tgctacacct attaaccctt agctttgtgc tttgggcttt tattgctgga atttgtatag
    22861 tagactcatc ataactatat ttttgtatgt gaaaaggcaa gaggctatga tgaaaataac
    22921 actggctaat tgcatgaggg agcatatcgt tgttaaagcg tcattgatag tatgaataaa
    22981 tatctcgata atattatatt gttatttact taatttattg attagtcaag caaagataat
    23041 cttctgttac ttaacgagac tagtaggtac aagcacttca tgttatgtac gacccaaaaa
    23101 tattgctgtt gattatttgc tgaaattatt gcgagcttca atttattttt aaaggacttg
    23161 gtaggctgcg tgatgaaata agacttggaa ggctgtctaa accaatatat agtagactaa
    23221 atagtaaaaa agagcatggt aattgtctct ttgtcaataa gtctaatggt aataagacaa
    23281 gttggagatt gagaatattt ttattgtgta acctattttg aagcgtactt aactagcccc
    23341 ggccaaaatc aaattttttc ggggtatatc aagggtttgc gtcaataaca gaatgttatt
    23401 tatctatcac gttccttggt ggcgtgtaga gttgatggtt acgtagtagc gtatctacca
    23461 gacgcgtaaa ttttcttgcg gttaagacgt gtgctcgttt gtgtttattt ttgggacctc
    23521 tttacatttg ctttgataaa aagctttata ttgaggaaga tattttttta cagagttgga
    23581 agcttcaact aagtagtatc taaaatagcg actcctttgt tttgtcagag gtgtattttg
    23641 tgaccgatag ttaacagatt gtttgccttt ccaacataag cctgcgtatt ttgccaattt
    23701 tgtttgatct tcaaatcgtt caatttgacc gatttcagcg attaatccag cggcgtgtac
    23761 ctttccaata cctggaacac tagtcaaata ttgatattct ggaataacga caacaaattg
    23821 ctcggttgct ttatccaagt ctttgatgtt cttttcaagc gcacgaattt cacatacaaa
    23881 aacatttaga acgacattga tggattctta tgcaagacta tctaaccgat aactcacggc
    23941 aattgcacgt tgaatcgatt tggcattttt ttctggatct ttaaagcgac atttcctttt
    24001 tcttttagta agtcacagaa agcttccaaa ggaagcacag ccaattcatc tagcgtgaag
    24061 tcttctgtca caagagtaat gacagtggca ctatagagac ttgtcgattc atcgcgcatt
    24121 tatcgagtaa gcgtattgca tttgtacgtt agattttcca gaaagtgttg ttttgtacga
    24181 gtgaagttgc ttaatgagtc gatagcgagt gcgtgttaaa cgctgtaaag ccacgtactt
    24241 ctcttctttg ataggagaag ttgtgaaccg ttgaatacgc aataaatcag caattcttaa
    24301 cgcgttgttt cgatcagtcg tatcttcctc aaacatgcga ctgaattgtt tcatccgaaa
    24361 aggattttca atcctcacaa gtgcattgag tttttttagc tctgcatctt catggaaaaa
    24421 catcgaagga tgaaagctgt acatggacgt ttaattccat ctcaataacg atttgaccga
    24481 agtgattgtt ttcattgaac acaagaatca gttctcgtgt caatggagcc ctttcaatgt
    24541 cattagcaac agaattttca gtcaatatag atagctgatc gtcgtctgtt aggaagcaaa
    24601 cgtctaattt ttcagaacta acgtcattac caacaaataa tttcatggaa taaaaaccta
    24661 ttttcgatat aaattctaga aaatgcttcg atactgtggg attccacaga aactcactgt
    24721 gtggtcacga cctcgcctaa tagaatacgg taataaaaga gctaatgagt tgatagtaaa
    24781 cacagcgctt tggataacag acttatgaag gtagacaaag ctacaggact gattagcaaa
    24841 ttctcgttga atcctttcca tacatccatt gtactctgag aaatcacaca ataacgaaat
    24901 aaattccgga aggaatatgt tattcaaaaa aatttgtgtt ttatagatac tttaaaagaa
    24961 acttattagg caaaatatat tttacgaaga ctgatgagtt gtgcaaaatc aaatctgagt
    25021 cagaatgaac ttcattctag ctcagatttt tgtttaatga cttcagtcag tttcttgcat
    25081 tacgtgaatg aaaatgggac tggtgatgtc caaaccctaa aaagttagac caaaatctaa
    25141 cttcaggggg gatggtattt ttatgggaaa atatagcttt gaattcaagt caacaatcgt
    25201 tcaagagtat cttgaaggag aaggtggatt aggatattta gcaaaaatac aaggagtgag
    25261 atcaaaaaaa ggtacacgga tggatcaatc aaaagttaga ccaaaaaatc taacttttgg
    25321 gggtcgttat ttgtatggca aaatatcctt ttgaattaaa actaaaaatc gttaaagaat
    25381 atcttagtgg cgtgggcgaa tatcggcatc ttgccaacaa atacggtatt tcaagcaagt
    25441 ctcaagtaag tgattgggtg aatgcctatc gtgaatacgg agaggaaggt ctattgaaaa
    25501 agcatcaaaa tcagaaatat tctgttcaat ttaagttaaa tgcgctagag ttatatcaaa
    25561 caagtgagat gtcctatcga gaagttgcca gcactttaga aatgaacaac cctgcgctta
    25621 ttgccaattg gatgcgtaat ttcagagaag caggtattga ggggctctca aaagagaaag
    25681 ggcgaccact tactttgact agaaaaaaag aaaacaaaaa agaaaataca acaactgaag
    25741 aacgcgagcg tatcaaggca ttagaaaagc aagtccgatc ccttcaaatt gagaatgcct
    25801 ttttaaaaga gttgaggaag ctgcgaaaac aggaagccca gcaaagacgc aagaatcaat
    25861 cgcacgaatc atcgccagcc tccgaggatc attcaaacta gttgagcttc ttgaaacatt
    25921 gaaatttcct aaagcaacct atatgtattg gcagaaacgg tttgacagac caaacccaga
    25981 ccaagaaatt gaagaaaaaa tgcttgaaat tcgcaaggag cataaagact atggctgtct
    26041 gcgactaaaa aaagaattag agaatcaagg gattcatgtc aataaaaaga agattcaacg
    26101 tctgataaaa aaactaggta tcgaagtaaa gtcttacact cgaaaatctc gacggtacaa
    26161 ttcttatcat gggaaggttg gcactgtcgc caaaaatcgt attcatcgtc ggttttatac
    26221 aaatatctgt caccaaaaaa ttacaactga taccacagag tttaagtatt atgaagtaga
    26281 caccacaggt gtcgttcgtc agaaaaagct gtatttagat cctttcatgg atttctacaa
    26341 tagtgaaatt ctatcttatc ggatttctga aaaaccaaac gcactagcca taatggaagg
    26401 attagaagaa gcaatccaga tgacaaatga ttgtccattt cgtagaacct tccattcaga
    26461 tcaaggatgg gcctatcaaa tgaatgctta taagaataaa ttgaagcagc ataaaatctt
    26521 ccagagtatg tctcgtaaag ggaattgttt agataactca cctatggaaa acttctttgg
    26581 tttattaaag caagagattt ttcatggaga agtctatcgg agtttagatg aattgaaaac
    26641 aaaaattgac caatatatct attattacaa ccataaacgc atcaaaaaga aattaaattg
    26701 gcgaagtccg gttcagtttc gagaagctgt aaaaacagct gtctaacagt taattttatc
    26761 gtacaaaaaa ggagtggatt tctccactcc ataaaagtct aactttttgg ggtcgctaca
    26821 aatgcttatc gagaatttgg agaagaaggc ctcttgcgta agcgaaataa gcgaagttat
    26881 tctgttcaat tcaagataga tgcgatagag ttataaaaaa cgggtgagct atcctatcgt
    26941 gaagtggcga atcatttagg gataaaccaa cctgcgttag ttgtcaattg gatgaaaatt
    27001 tttgttcaaa aggattgcac gggctctcaa aaatgaaagg gtcctcctcc attttgtcta
    27061 agaaagaata aaaggaagaa acaagcaaac tgacgcctaa agagcataat cgtatcaaag
    27121 aattggaaaa ataagtgcgt ttccttcaga ttgagaatac ctttttaaaa gaattgagga
    27181 agcttagaaa acaggaagtc taacaaagac gaacgaatca atcgcacgaa tcatcgacaa
    27241 cctccgagga tcattcaaat tagttgagct tcttgaaacc ttgaaatttc ctgaattaac
    27301 ctttatgtat tggcaaag
//
LOCUS       DACGMI010000039        25614 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.040, whole genome shotgun sequence.
ACCESSION   DACGMI010000039 DACGMI010000000
VERSION     DACGMI010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.040"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            108..971
                     /locus_tag="IXT46_001846"
     CDS             108..971
                     /locus_tag="IXT46_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4947751.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1100..2722)
                     /locus_tag="IXT46_001847"
     CDS             complement(1100..2722)
                     /locus_tag="IXT46_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4947752.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            2971..3492
                     /locus_tag="IXT46_001848"
     CDS             2971..3492
                     /locus_tag="IXT46_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947753.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(3678..5408)
                     /gene="spxB"
                     /locus_tag="IXT46_001849"
     CDS             complement(3678..5408)
                     /gene="spxB"
                     /locus_tag="IXT46_001849"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAQ4947754.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5573..6391
                     /locus_tag="IXT46_001850"
     CDS             5573..6391
                     /locus_tag="IXT46_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAQ4947755.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6494..6691)
                     /locus_tag="IXT46_001851"
     CDS             complement(6494..6691)
                     /locus_tag="IXT46_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947756.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            6860..7438
                     /locus_tag="IXT46_001852"
     CDS             6860..7438
                     /locus_tag="IXT46_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAQ4947757.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(8483..8986)
                     /locus_tag="IXT46_001853"
     CDS             complement(8483..8986)
                     /locus_tag="IXT46_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAQ4947758.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9345..10370
                     /locus_tag="IXT46_001854"
     CDS             9345..10370
                     /locus_tag="IXT46_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4947759.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            10717..11595
                     /locus_tag="IXT46_001855"
     CDS             10717..11595
                     /locus_tag="IXT46_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947760.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12071..12187
                     /locus_tag="IXT46_001856"
     CDS             12071..12187
                     /locus_tag="IXT46_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAQ4947761.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13115..13453
                     /locus_tag="IXT46_001857"
     CDS             13115..13453
                     /locus_tag="IXT46_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947762.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13547..13777
                     /locus_tag="IXT46_001858"
     CDS             13547..13777
                     /locus_tag="IXT46_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947763.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14177..14548
                     /locus_tag="IXT46_001859"
     CDS             14177..14548
                     /locus_tag="IXT46_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAQ4947764.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(14822..15514)
                     /locus_tag="IXT46_001860"
     CDS             complement(14822..15514)
                     /locus_tag="IXT46_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4947765.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15517..16302)
                     /locus_tag="IXT46_001861"
     CDS             complement(15517..16302)
                     /locus_tag="IXT46_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4947766.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16539..17939
                     /gene="lacG"
                     /locus_tag="IXT46_001862"
     CDS             16539..17939
                     /gene="lacG"
                     /locus_tag="IXT46_001862"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAQ4947767.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            17964..18281
                     /locus_tag="IXT46_001863"
     CDS             17964..18281
                     /locus_tag="IXT46_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4947768.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18294..19967
                     /locus_tag="IXT46_001864"
     CDS             18294..19967
                     /locus_tag="IXT46_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4947769.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            19981..21612
                     /locus_tag="IXT46_001865"
     CDS             19981..21612
                     /locus_tag="IXT46_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAQ4947770.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            22484..23674
                     /locus_tag="IXT46_001866"
     CDS             22484..23674
                     /locus_tag="IXT46_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HAQ4947771.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            23808..>25614
                     /locus_tag="IXT46_001867"
     CDS             23808..>25614
                     /locus_tag="IXT46_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4947772.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQ"
BASE COUNT         8130 a         4270 c         5108 g         8106 t
ORIGIN      
        1 attttgatta gaacttgcga aaataaaccg gttaaagtgt gtctagcgca agagatttgc
       61 tataatagac gataagggta aaatgtaacg agaaggggtt gaaaaatgtg tatcaaattg
      121 taacagattc ttgttgtgat ctgccatacc atgtattagc aaaagaaaaa gttgattttt
      181 tatcaatgaa tctccaattg aatgatcaag agttagtaga tgacctcgga aagacattca
      241 attatgaccg ctacatgaat cagctgaaaa atggtgcgat gcctacgaca tcacaaatca
      301 atgttggccg atatttagaa tttttccgtt cttatgcgga aaaacagatt cctgttttat
      361 atgtggcttt ttccagtgga ttaagcggct cttacagtag tgcgcttcaa gcggttgaat
      421 tgctgaagga agaatatgaa gaccctgaga tctatgtttt tgatacaaaa gctgcaagta
      481 ttggggaagg gcttttagta ttggaagctg taagattgaa aaaagaaggt aaaagcatcg
      541 aagaaaccct agagtggctg gaaagtaatt atttgaaagt ccattcatgg gtaacagtag
      601 acgatctgaa atatctagaa cgaggcggta ggatttccaa agcaagtgct actcttggca
      661 gtctattgag tgtaaagcct attattacgg tggataaaga aggaaggctg acgaatgttg
      721 acaaagttcg aggaagaaac aagtcgatcc agacaatcgt caatgagacg gtaaaaacaa
      781 tcgttgcacc acttgatcaa atcgtttatg tggcttacgc tggggatcta gagagcgcgg
      841 agaaggcaaa acggcttttg gaagagcaga taaagatgaa agatgtgaag ctttatccct
      901 taggaccaac gatcgccagt cacacaggct atggctgtat cgcgattttt tcgatgggaa
      961 tcagtcgata aaagcagtaa ctcattctgt aaaaaagccc agaaattgat tgtaacaaaa
     1021 acagcgactc ttaaaagata gatgagcatc ctatctctta gaggtcgctg tttttttatt
     1081 ttttaagcta aataggccat tatgcccata actcgttcaa ttgtttttga atatctgcat
     1141 tttccaaaaa ttcatcatat gtcgtatcag ctcgatcgat cacaccttta tccgaaacgg
     1201 caatgatgcg gtttgccaat gtttggataa attgatggtc atgtgacgca aataagattg
     1261 agccagtaaa tgccatcaag ccgtcattca atgctgtgat tgattctaag tctaaatggt
     1321 tcgttggatc atctaataca agtacgttag ctttcgaaag catcattttt gaaagcatgc
     1381 aacggacttt ctctccacca gataaaacat tcactggttt caatacttct tcaccagaaa
     1441 acaacattct tcctaagaag cttcttaaga aggtgttatc atcttcttct ttacttgcat
     1501 attgacgcaa ccagtctaaa atcgttagat cagtatcgaa ttctttcgtt gtatcctttg
     1561 gtaaataaga attacttgtt gtcacacccc aacgtactgt tccagtatct ggcgtaattt
     1621 cacccatgat aactttgaat agcgttgttg ttgttatatc attttctgcg acgaaagcga
     1681 ccttgtcttc tttgctcaaa ttaaaagata tatcatctaa aattttcttt ccatcaatcg
     1741 ttacacttac attttctacc tgcaataagt cgtttccaat ctcacgttca ggtttgaatc
     1801 caacgaatgg ataacgtcta gaagaaggtt ggatatcgtc taaagtaatt ttttcaagca
     1861 tttttttacg tgaagttgct tgttttgatt ttgatgcatt cgcactaaag cgggcaataa
     1921 attcttggag ttctttgatt tgttcttctt ttttggcatt tgcgtttgct tgaagtttag
     1981 ccgctagttg actagattcc aaccaaaaat cataatttcc tacataaagt ttgattttac
     2041 caaaatctag atccgccata tgtgtacata ctttgttcaa aaagtgacgg tcatgggata
     2101 caacgatcac agtattttca aaattgatca aaaattcttc cagccaattg atcgattgga
     2161 tatccagacc gtttgttggt tcgtctagca aaagaacatc aggtttacca aatagtgttt
     2221 gtgctaataa cacttttacc ttttgtccac cagttaattc actcatttgc tgatggtgca
     2281 attcttcagg gatgttcaga ccttgcagta aaacagctgc ttctggttca gcttcccatc
     2341 cattaagctc agcaaattct ccttctaatt cagctgctcg aataccatct tcgtcagtga
     2401 aatcctcttt catgtaaatc gcatcttttt ctttcagcac ttcatacaga cgcttgtgtc
     2461 ccatgatgac tgtttcaagt acagtatagt cttcatagtc gtaatggttc tgtttcaata
     2521 cggccatccg ttcatctggt cccatagtaa cggaacctgt ggaaggctgc agatcccctg
     2581 ataacacttt aaggaacgtt gatttacctg caccatttgc accaatcaag ccatagcagt
     2641 ttccgggggt aaatttaata ttcacatcat caaatagttt gcggtctgaa aagtgcaaac
     2701 tcacatcatt tacagtaatc aatttttttc ctcactttta tcattattag ttttgacaag
     2761 tcttatagaa ttatataggg gaaaggtaaa agattcaagg caatcgaaca ttctttgtgt
     2821 ttcacgtgaa acagaatgaa aaaaataaaa ataaaagcgg agcgaaaata gctactatag
     2881 gatttattag tttgcaacag cataattttt gacgttattt ataagaggga gtactataaa
     2941 actgtaaaag aaatgaaaga aggattgaaa atggatgaaa aaagaaccat cgactggggc
     3001 tcattgattt tgggaatttt atttgtactt gtctcattgt tatcatttca agaccctgtc
     3061 ggaaatttag ttgcaattgt agtagtcttt gcgatttttg cctttattaa agggatattt
     3121 gaactgtttg tacggaacag attaaaagag ctaacaggat ataaaggaaa gatgccctta
     3181 ataatcggga tcatcgatat tctagttggc gtctttttct tattcaatat tggtgcagga
     3241 gtcgcagcat tgccttttgt ttttgcagta tggtttattg ctgattcagt tttagcgtta
     3301 tttactgctg acttggcaag aggagtaagt gaaggatatt attggtttac gatcatcgtc
     3361 aatattttag gaattttatt aggaattttc ttattgttta atccaatttc ttctgcgttg
     3421 acattaagct ttttagttgg attctatttt atgttatttg gtatcacaca tatcgtctat
     3481 gcatttagat aagtaaaatc aaacaaataa aaaagccggc ttccgattac agttttactg
     3541 ttgtaattgg aagccggctt ttttatcatg gacaaatatg cacgaggtga tttttaggtg
     3601 tcgagacaaa tttatgcaaa aatgtgagaa gctatataca caaattttat cttaatactc
     3661 gaagcatagc gcagttgtca caacctcttt tcatataatt cattcaatac tggcaaatca
     3721 tggacttcat atttttcttt gaatgcttgg atttcttctt cagaatattt tcttggatct
     3781 aaatgcagat cttctactgg caatgggcgc ttgttattga tcttcacatc gattactaca
     3841 ggacgatctg attttgcagc tgcatcaaag gcaaatcgaa gttgcgagta ttctgtgact
     3901 gtaaagctat ttgccccgag cgcttctcca actttaccga aatctgcatc ttctaaaaat
     3961 acaccaaatt tcttttgttc cgtatcttct tgttctgctt cgatgaaacc aaaagaatca
     4021 ttcgaaaaga caacattaat aattggaagc tgatatttga cttgtgtaat gatatcttgc
     4081 atgaccatag caaacccgcc atcaccactt aaggtaaata cttgtttttc tgggtagctt
     4141 agttgtgcgg caattcctcc tggcacacca ttacccatag ttgcgaacca tccagatgtc
     4201 gtatgttttt gtttaccgtt catattcaat aaacgaatag aatggatagt cgtgttaccg
     4261 acatctgtga cgaaaatcgc atcgtcttca gcaatacgat tgatttcttt atagacagcc
     4321 tctggacgaa tcggttcttc ctctcgatct tcaaaagatt tcaaccaatt tacccatttt
     4381 tctttatttt cttgatttgc taggtaccag ctatcagcag ggcgagcatc ccctaactcg
     4441 acaagtcttt gcaaagctgt gtttgcatca ccgaggatcg acaaagatgt ttcatggcgt
     4501 cgtccaaatt ttgacgcatc gatatcgatt tggataaatt cagcagttgg attaaaaaat
     4561 gcacgtccaa atgggaagtc gctaccgaca aataagatca gatcggcttc tgccaatgct
     4621 tcatttccgg gtttagtagc gacacgtcca gcaaaaccaa gaaagttttc ataatcatca
     4681 ggaataattc cttttgctag aacggaagcg acaacaggaa ctgaaaaatg ttctgagaat
     4741 tctttgattt gcggaaatcc gtttcgcgtt ccttgaccaa cataaagaac tggttttttt
     4801 gctttttcaa gataaggcaa agcagctagc aaatcttttt cttctggtaa tatcacactt
     4861 gttttgtgag tgtgagcggt ggagaaaggt tgttcgtcaa tttcttcaaa accaagatca
     4921 acagggatag tcacgatagc cacgccttta tgctcatagg cggctttaat ggcttcatct
     4981 actacatgcg gaagactttg tggtgtcatg actgtacgat tgtatacgct aacatctgcg
     5041 aaaataggat tttcatttag ttcctggaaa gagttatagt tcatggatgt agaagcaact
     5101 tgtcctaaga acgctactag aggcacatgg tccatctgtg catcatacaa accattgatc
     5161 aaatgtgtcg caccaggtcc tgcagagccg aagacagcgc cgactttccc cgttaatttt
     5221 gcatctgcag cggctgcgag tgcgccgact tcttcatgac gaacttgaat gtagttgatt
     5281 tcggtttttt cttgatatag cgcatccata attgaattga aagatcctcc gggaatgccg
     5341 taaatatggt cgatacccca gctttcaaga acttttacca ttgcgattcc tgcattgatt
     5401 tttgacatgg tgtttcactc ctttagcaat gatgatacat aaattttttg tatctagagt
     5461 atagaacttt ttatcgaaaa tcccaactaa ttcgtctttt cacaaaaatg tagtcatgtt
     5521 tttgggaata tgctagagta gtacatagat agattcaaga gaggggaatg gcatggttga
     5581 atggctattg agacttgaac cttggcagca agcacttgct gggacagctt ttacttattt
     5641 tatgacagct cttggtgccg ggttggtttt tttctttaaa gaaatcaaaa aagaagtgct
     5701 aaacttgatg ttaggatttg cttctggtgt catgattgct gcaagttttt ggtctttgtt
     5761 agatccggct attacaaaag cagaagaaaa tggagatatt gcttggctag ttgtaagtat
     5821 tgggtttggt ttaggcggtg tgtttttata tatggcagat aaaacactgc cccatatgca
     5881 ttttggacca caacatgaag cagaaggatt gcctacccat ttaaaacgga cgatcttgct
     5941 tgttttttct attacattgc ataacattcc tgaaggttta gccgtggggg tagcattcgg
     6001 tgcagcagca actgcggata atccgacagc cgctatatta gccgctgttt cggtggcgct
     6061 aggtattggt atccaaaact tcccagaagg agcagctgta tcaatcccgt tgcgacaaga
     6121 aggtctgagt cgtaaaaagg cctttgttta cggacaagct tctggaatcg ttgaaccaat
     6181 tgctggagtg attggagcgc tactagtaac gaaagtggag ctgctgcttc cttatgcact
     6241 tgcttttgcc gcaggagcaa tgatttatgt cgtggtggaa gaattgatcc ctgaagcaca
     6301 gcagacattg tccagcaaac gtcattttgc agtttttggc gtcatgagtg gatttatcat
     6361 tatgatgatt ttggatgtgg cattaggata aataaaaaaa atatatatga tatatcaaat
     6421 agggccgcga acttatatcg cgaccctatt tttttagtaa gttatatcat aatgaagtga
     6481 atggtatcat acattaataa tagttttttc tatgtgtatt tcctttgatc cagcgaacaa
     6541 gccagatgat aagtgcgatt gggattagaa ctttgaccgc aaaccataaa agcccgctta
     6601 ggacactgac aaaaagactg atgacgaagc tagctgcaat tagcactaaa agaaccatga
     6661 agatatttaa gaacatattt ttttgacgca tacaaaaccc tcctcttgtt cattctttac
     6721 tatagaaaaa gtataacagg gattgtttaa aaacacctcc aactgaagac tgatttttac
     6781 ttcatctact taaatgatca aacaattgct ttttctctgg tttatcatct aaaatagagc
     6841 ggaaaaggag gagaatatca tgcctaaaaa tcgtcttgaa gcatttacag atgctgtaat
     6901 cgcgattatc atgactattt tagttttaga acttcatgaa cctaacggag acacgtggga
     6961 ggcgctcgct gcattaggtt accgattttt tatctatatt gtcagtttta tcattttagc
     7021 gatttattgg aacaatcatc atcatttatt tcaagttgta cataagataa atggacgggt
     7081 cttatgggcg aacagtttct ttgtttttgc gctttcgctt tttccgtttg caacttcatg
     7141 gatcagtgag tacatcaata gcctggctcc agaaatgact tatggttttg ttaccttgac
     7201 cgctaatatt gcgtattata tcttggcaaa agaacttgtc aaagcaaata aaggccacga
     7261 gaaagcattg aaggcgatgt tgaataatta caagaaatcg tatctatcga ttggtttgaa
     7321 tgtgttagga attgtcttag ggtatttagt agcgccagta gccgtgctga tcgcaaacat
     7381 cgtgattcta gctgcttgga tcatcccaag tcgtaccatc gaatcacaat atcggtaaaa
     7441 tgatccgtgt ttaaaattta agagaaaaat atagaaaaaa taaataaacg atcaaatatc
     7501 cgagtgatac tagtattcaa agagggatgc agatggatca aaaaagaatt catgtaggac
     7561 tgattactag ttttgtcacg atgcttattt atttggatca aggtcatttg acttggacag
     7621 tagttggtgt cgtaggattt ttgacattat tcacagcaat aaaaaaataa acatctttat
     7681 gtaatctgat gttctatcta tttaagaaaa gcatgtttac agcagtatga ttctgttgta
     7741 aacgtgtttt tatttgtgga aaatttaatt tttagaaaag tgtatcgaaa aatagatagt
     7801 tagtttttcc acagtggata acttcgtaag agataaaaat aaaaaattag tcaaagaagg
     7861 gcgtatagat ttcttttgat aggagatata caacagaaat gaataaatat taacgtgttt
     7921 tcaaacagta taaaacggtg tggtttttgg aataaaaaaa taacatatct cattttacgc
     7981 ttttgttatt ttatacttaa aaaataacga cacagaaaat accgtgtctc agatttctct
     8041 actacttcta aaaactactg tttttttcct ttgaaatgcc ttcaaaaagt aggatcaggc
     8101 agaatatact ggcagaatca aggagaaggg agcctaaata aggagaaaaa ccatagaaaa
     8161 tataaagtaa ttacttataa aacaagcttt ttatagaaaa ataatatacc tgagtagggt
     8221 ataaattaag acggaattcc tttctagatt gagatattga ctaggaagaa tgttaagatt
     8281 ttaagccttt aagctaaaaa aaaacccttt ttgttaaata aggggaatat agcctgtcag
     8341 tttcaaactg caagtcgtcc tgctgcaata atatagtaga ttagagatga aaatagattt
     8401 ttttaaacca atgactgaat aaaaagaccg tcatagatac acattggaat gtgtctatta
     8461 cggtcttttt ttacgaacga ttttattgaa gacggacagt tcgggtcaaa aataaaaaag
     8521 ctacgatcag aaataagaat aaaatgtatc ccaaaataat ggctagacgg tctaacttat
     8581 ttgtcgatag atgtttgttt agaagttgat aggcccataa acctatcagt cctcctgttg
     8641 tattagttat caaatcagtg atgtccgcta cgccaatacc gaataggaat tgaatcaatt
     8701 ctgccaagaa gcttacaagg aaaataatcc ctaatttttt agaaaaagaa agtctcttga
     8761 aattgacatt caaaagcacc ccaaaaggaa aaaagacaat caagttataa gtggtctcac
     8821 gtaataccgt cgtattttca aaagaaaaag tagaaaaagg gacgagattg acattgctgt
     8881 aagaataagt gagaaattgt ggaagattaa atgatagctt gaataaaatc aaccataata
     8941 gaaagaataa ataaatccct aataaaaatt ttgatacata ccgcatagac atctcctcca
     9001 tttaaaaagt ataccatcga aaaccgctga aaaatcataa aaaagtatga agtttaagga
     9061 ccaacgtagt tatcgtacga aaattagaag cttttttttg ttgggaatcc ggtttcttta
     9121 acaaagctaa gatagcgagt tgcttggaaa agttgctatc ttttttctgt caaaacgact
     9181 cggaatgttc gttttttgtt ctaatttctc caagttgttt actttttgat actaagttta
     9241 tgaaaaatca agaaatagtt gttatactag gtaatgctga caaacgggat tggcatttca
     9301 tcttggttca gctttttttc caattactag gaaggaggga tagattgttc aagacttatt
     9361 ttcgtttcaa taaaatacaa gataatcctt ttcgtatcat gaatctgatg ctacttatct
     9421 ttattgtatt atggttaggt tacataaatc atgatttttt gatttcaagt ttttcatcat
     9481 tagggatctt tacttttttc tattatcaaa acataccgat gaaatatttg ctgaaacgta
     9541 tgtttctgat cggttgcgga ctgttggttg ctttcgtttt ggggatctta tcgacttatg
     9601 ttttatggct tgaaccattt gccgtagctt tggttgcttt ttccagcaga ttcgtgttgc
     9661 gattattcca tatttctaaa ccaggtggct tgttttttgc gatgctttct gccatgggaa
     9721 cgagcatgca gctgccaatc gctcaattac cgatcgtctc actttatttt tttatgggtg
     9781 tcgtttttgc cctgattgcg gcagtgatta caaaattact ggattcacgg cctgagcaga
     9841 caattgaaaa agcaacttta aaagaaagat ttcacgaaga gcctttagtg atcattgatt
     9901 ctgttttcta cagcgctgcc ttatttcttt ccgtttatgt cagtcacggc ttgaatctgc
     9961 ataatcctta ttggttgacc ttgtcatgtg catcgatttt gctagcagaa aacttggatg
    10021 cgatgaagca tcgacaagtc caatatctga ttggatcgat gggtgggtta tgtgtgtcgg
    10081 cattcttgtc atttgtgccg tttacgcagt tgcagaccat ttttctgatc acttttctat
    10141 atggaatcgc acaatttcta gttgctagaa attatgcagt tgctaatatt tttcttaatc
    10201 cgatggcgtt gatgctatct acacttattc gtggagcata cttgatttct ttgatcgaat
    10261 atcgtttttt agggatcgtc ataggaagtt tcatcggttt aggtgttgcg tgggtaatga
    10321 cggttggttt gcaacattat ttaacggttg ttcgtcaaaa attagaatag aaggacaaat
    10381 atatgtgcca aaagaggtta tgacaagatt tttgtcacaa cctctaattc aaggtgttca
    10441 aaagccagat tctcagcatt aagtcaaatt cacacaaaaa tgtggaaagg aactttcaaa
    10501 aaaattttat atttattcta tcaaaaaatt ttatatttat tctatcaaaa aattttgttt
    10561 atgatggtaa ctgaataaac tttcctgaga tggtcaatgc tttccttgaa agtcttacag
    10621 atattctttc ttcatagaaa gtttaagttt tatagttagt gtacaataaa agtatgttta
    10681 taccatatgg tgtccggata atcagtcatt taaacaatga ggttcaaaga tatgaaaagg
    10741 ggaaatttga tgaagaaaat aagcaatgaa atccaaattc tggcagaaac tttaactctt
    10801 cccaaagtcg ttatagagca aatgattgta caagcaaaaa acatccttga tgaggtgttt
    10861 gagcaatata gtcatgaact aatggatcct aataaagcaa aggcgactgc aaagaaaata
    10921 gacaaagtct atgaagagga accttttgca gcattagcta tttatctata tgcagcttct
    10981 caaagttgga aaaaaattta tcaaccattg aagattccaa gaactatcta tttggcaaca
    11041 atgaatgctt ttactagatt tattcatgaa catttccaag taacaggaag ctatcgcttt
    11101 gaccgtggtt tttggatttg gcattacact agtggcttga tctttcggat tggtgaattg
    11161 gagtacgaaa tgacatattt tccgaaaggg tacacggatc taagattaga aggaaagcag
    11221 tgcctttctc ttcatattcc ttccgatgca gatttatctc agaataagat aagagatagt
    11281 tacgaaagtg ccattcgttt ttttgaactt tattttcctg attaccatta ccaagtgatg
    11341 tacacagata cttggttact atcacccaat cttactaaat ggttgaaaaa agagtcaaaa
    11401 atctgtcttt ttgcagccga ttatcgatta ttatcagttg atgaacagga cgatagtgga
    11461 gtcccttgga tctttggacg agtagatgcc caaatacatg attatccaga aagtacgagt
    11521 ttacagcgac aagcaaaaga gcaattgctt gcaggcgagc acattggctc tggcttaggt
    11581 attcttactt cataagttta gtacttcgaa atagtttaaa agagcgtgag acaaaagtaa
    11641 agaacacttt tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt
    11701 cggaaataag ctgaaattca caaaaatttg aaaagcaatt ttcgtgaatt tcttcttatt
    11761 tcttggagtt aaacgcttct gtcccagcct cttttttagt gttctatcga acacacagta
    11821 cgttcaatag gtaaactagc tataacaata gatattaaag ttaacggaca agagggcctt
    11881 ttttaggtag ctaaaacgta ataatgaaaa tttatttcca gagataggag tcaatcagct
    11941 agtctgatcg actgttttaa caagttgact ttcattttaa cttttgatac catttaaaac
    12001 acaaatcgta attgtttcga tttgtgtttt ttagcatgac tacaatcaaa gaagaaagtg
    12061 ggtcgtccat atggaaaaaa cagatatctc aagtgcatac cgccgcttga aaagcccaaa
    12121 tatcaaaaca cgaaaacgtg cgctgaagat catcaaagat gtgaaacgga atagtgggaa
    12181 aaggtaagaa gaaggaaact taattaaaaa aatagccgaa aaacgttttt cggctatttt
    12241 caataatcgg tttttgtgta aggtttccga aagaactgct gttgattttc catttttaac
    12301 atatgataaa ttggtagaat ctttcttttc aaattgatac cattccctaa ttccagttat
    12361 atagttaact acagaaccac aaagcacgta cgtttataaa agtattatct gtagttattt
    12421 ttcaattccc tttcaacctc ttattttgac cagtagtatt gatcacttta ccttttaaca
    12481 cctttgttcg tttttgaaac atttttagtc aagaatggaa acgtaactac ataatcaaag
    12541 gttttgcgaa atatttcatg aaatatttca tgtagaagcg agcaatacgg ttgcaaataa
    12601 ccattatcgt ttaataagca gttacgaaag ctcccaatat ctctaacgtt cagctcactc
    12661 catttctttt cttcaaaaaa atcagtgatt cgtatctctt tctatttgtc gaaaaagtta
    12721 actttaaaaa gtaacgccga aaaaatatgc aaaaaaataa aaaagcagtt actattgcta
    12781 gaataacatc aaggaataat aagttttggt tttcagataa tagtcgataa gttgtgtatt
    12841 ggaattttag atacagtaat aaagtatttt tcatgaaatt ttgtgagaat cactattaca
    12901 agtatcttta ataaaattaa tggttaagga ggaacttaaa gtagaatgta aatgaatagt
    12961 tgtagtcagt cgattgtgat actagactca aagttgcagg aataagtttt tcaatttgtg
    13021 attggaagat aaaaaatgaa aaagaagggc ttttttttat actttgttga ttgtagtgtt
    13081 tattttccct ctgtttagcc aagtaacatt ttctatgact caaccagttt caagtgagga
    13141 acatgataac ctttttcgtg ctacagaaga gtttaagaaa tatcaggaaa atattgttcc
    13201 ggagactcca ttagctagtg agccaattac tgatattgat ggaaaccaaa taggatggta
    13261 tatacagtac gaagttatgg tggtaaataa tgactcaata gtaaaaaata cagtaggctt
    13321 agagctaaca ccgattgaaa aggtgagttc attgttaacg tatatttata ctgatgaaag
    13381 tgacgagact gagatcattt taacggatta ctcaaaaatt gctactgata aaaagtatat
    13441 attgtggatg tagacactag tgaaatactt tatgatatag aaattgatga aaatttacta
    13501 gatgtagcac aagaaatcga tcatcaaaag caggaagcta ttcgatatgc tggtagaaaa
    13561 gggaaaagaa aatatttatt acgtgaatgt agcaaaagtt agagaagatg aaaatgagtg
    13621 gaaagaattc aagagtcgct actcaattaa ctcgactccg acatttacag tttacagaga
    13681 aggatcgata gaaaaaactg ttttttggac taaagaaagt ggaatgtctt tagctgaagt
    13741 agaagagttt ttggattatg ttagtatgca acagtaaggg agttcttatt atgaaaaatt
    13801 ttgacacata ttatgttatt gttttttcga tatctttgct gttaatatta ctaactttaa
    13861 tgcagtataa agagtatcca gagtatttta ttttaacttt tgtatattta gtaagtagct
    13921 acacacttct atataaattc agaagttctt ctagagtttc taaagtttgt ttcttaatta
    13981 gcttattgat tctataatat ttttgattta tataggaaat taaaaatatt atagaatcaa
    14041 cactcagaga acgggttggt ttttaataga tttaataagt actgataatg aaatttctcc
    14101 tggttgggaa aacgaagttg gttaccctgt agaagaattt tttcaagatt actttgcgga
    14161 gtatgccgat aggataatga gagattacgt aacagataaa actcaagaag tcatcaatca
    14221 atcccagtca ttaaatgaat tatctgataa ggcgaaagaa gaagcagttg ccattatttc
    14281 ttcagggatt agtgactata ttgatatgag tggtgaaatc aattatggcg ataaagacaa
    14341 aattgtacgc atgataaaag cttttatcaa aacttttgat gtgaaggcag atcttaagtt
    14401 taatgatact tacctagtag gaaaattaat taatatcctt gggacagaga aagatacgga
    14461 aacgtttatt tcctctttgt ctatgttgtt tacagataag catttttcaa ctcagcttgg
    14521 tggagaggaa ctagtggaaa tcttttaacc attacgccca gcattaataa aagtatatca
    14581 aaaaagtact cctgatgatt tttaagattg gtttgagaaa taatgtgaaa acactatttt
    14641 taatgttaat tatagataga gatgaacgcg tcatatggtt aaaagaatga aaaagtcaaa
    14701 gatacactgc tatatttcac taaggatata gcagtgtatc tttcatgtcg tttcactggc
    14761 agttttttat aaaaggaggt gtgcatttca gttgcttttc tttggtagtt agttgaatcg
    14821 tttaagaatt aacggatgtg gcagacaggt gctctgtcca aaaaccagta aaatctttga
    14881 tggttccatc tttatttagc tgtgcctgtt caaatactgt tttgttttta ccgaatggat
    14941 caattgcaat aattgttccg atccccgcac gtttggcagc aagtaatcct gagtaagcat
    15001 cttcgataac aagacaatca gccggagcta agctcagttt gtctgccgct ttaagaaaaa
    15061 tatccggttg cggtttccca gggaaagagc cgtcgtcata gacaatcttg tcccagtcaa
    15121 accagcgggc taaatcgaaa atatcaaaat aaaaagcaac attctctttg acagtagccg
    15181 tggcaatcgt taatggaatc tgttggtcag tcagctggtc aagagtcgct tcaagccctt
    15241 ttgtcaactg aagctcgttt tcattttgca agcaaagcat acgataatag ctttcttttt
    15301 cttctgacaa tacggcgatc tcagaggcgg tcaaatgctc tgaaatgaaa tgtttcaaaa
    15361 tctccgtatt cgtccgacca tgaatatttt ttaaaatatc ctcgtctgat aaaccatctt
    15421 ttgtatgatc atgtatcata tgcagccaag cagcttcatg cagatgagag tccaaaaaca
    15481 ttgttccgtt gaaatcaaat ataatccctt tcatagttac gctcctatag tggtattttc
    15541 ggttgaatca gcaatttgca gatcgacata ttgtgcatag tgctcttgaa cctcccgcga
    15601 gatctggcga tccgtaatga gcagatcgaa atcatgcaaa ttataaaaca cataaaaatc
    15661 atctcgattg aattttttat tatcaacgag tagatatttc ttacgggaat tatttagagc
    15721 gatctgctgt gcttctcctt cttcggtact gtaagtagag atcgcttcgt tgtgaacgcc
    15781 atttgaactg ataaatgctt ttgtaaactt tagtcttctt aaattgtcgt tggtgatcgg
    15841 tccgacaaat gcgccggtat ttttccggaa atcaccgcca atcagtagaa tttctggtcc
    15901 atctgcttga gcaagaatat caaaaactgg ataattattt gtaatgatcc gaattttctt
    15961 gttcagtaaa tgcgtcgcca atagttcgat tgttgtacct ggtcctaaga aaatcgtttc
    16021 tccctcgtga atcaaggagg ctgctgtggc agcaatttct tttttttctt gaatctgcag
    16081 agtggctttt tcagtgtgag aaagttcttg atctaaagtg taggaaagac tttgagcccc
    16141 tccatggaca cgcagcagct tgcccgattt ttctaattca tctaaatctc tgcgaacggt
    16201 catatcagaa acatctaatt gattgatgat ttcattaacg gtaaggattc cttttttatt
    16261 gaccatttct acgatagtaa gcaatctttc ttttttcaac attgtcttca cctctaattt
    16321 aaggataatc tatcatataa acggacaaca gtcaatctaa ttcgaacaaa agtaaacatt
    16381 tagggtggtt tttatgtttg ttacaataga ttttattgct gttttctggt ttttatgatt
    16441 atttgtgttt gtttttgttg acaaatgttt tggatgcgtt tacaatgcaa tcagttagaa
    16501 agagcgaaaa ctgattatag atttgaggag agatgtacat gcttaaatta ccagaagatt
    16561 ttatttttgg cggagccaca gcagcctatc aggttgaagg agccactaag gaaggtggca
    16621 aaggcgctgt tgcttgggat gactttttag aggaacaagg gcgattcagt cccgatccgg
    16681 caagtgattt ttatcatcaa tatgcaaagg acattgaatt gtgtgaacgt tttggtgtaa
    16741 atggtctaag attatccatt gcttggagcc gcatttttcc tgatggagct gggaaaccaa
    16801 atccagaagg aatcgctttt tatcatcgtg tgttcgaaga atgtaagaaa agaaacgtaa
    16861 cgccgtttgt gacgttgcat cattttgata cccctaaacg tttgtttgac catggagatt
    16921 ttttgaatcg agaaacaata gaagcatttg tttcctatgc cattttttgt tttcatgaat
    16981 tcaaagaagt caaggtgtgg agtaccttta atgaaatcta tccagttgca accaatcaat
    17041 atttgttagg tgttttccca ccaggaatca aatatgattt tacaaagatc gtcgcctgtc
    17101 ttcataatat gatggttgct catgcccgtg tagtgaacta tttcaaagaa aacgaacttc
    17161 cgggtgaaat tggtgtagtt cactcattag agacgaaata tgcggcaaca gacgcgccgg
    17221 aagataagca tgctgccttt ttagacgatg cattgtcgat ccgtttctta ttagatgcta
    17281 cctatttagg ctattattca actgaaacct tgactgctct tgatgagata tgtgaagcaa
    17341 atcaggccag ctatcatttt cctgaagaag atttcgttga attgaaaaaa gcatccacgc
    17401 gtaatgacta cttagggatc aatcactacc aatgccattt tgtcaaagct tacgatggag
    17461 aaaatgcaat ccatcataac ggtacgggtg aaaaagggac ctctgtttat aaagtgaagg
    17521 gaatcggaga acgtatttat aaagaaggaa ttcctcgaac tgattgggac tggctgattt
    17581 atccagaagg tctatatgac ttgttgctgc gaattaaaag cgattaccca cattacaaca
    17641 aaatctatat cactgagaac gggatggggt ataaagatca gtttgaagat ggcattatta
    17701 tggatcagcc gagaatcgac tatttgagag tctatttgga atccttaagc aaggcgataa
    17761 cagccggggt aaatgtgaag gggtattttt tgtggtcgct tatggatctt ttctcatgga
    17821 caaatgggta taacaaaagg tatggcttgt tttatgttga ttttgaaacc cagaagcgtt
    17881 acccaaaaga atcagcttac tggtacaagt tggtcagtga aaccaaaacg attatttaat
    17941 aagtgataat ggaggaagaa aagatgaata aagaggaatt acaaatgctt ggttttgaga
    18001 tcgttgcata ttcaggcgac gctcgcagta cattattgaa attattgaaa gaagtaagac
    18061 aaggaaactt tgaacatgtt gattcggcgt tgaaagaagc cgacgaaaat ttaacccttg
    18121 cacataattc gcaaacaaaa attttagcgg aagaagcatc tgggaaagag atggagatgg
    18181 gattcatttt tatccatggg caggatcatt taatgaccac tttattgctg agagatctga
    18241 ttcaagactt tattgtactg tacagacaga atcaaggata ggagaagaac gctatggatg
    18301 gaatcattaa acaaatcgaa aaagggaaac cattttttga aaaaatctca cgtaatagtt
    18361 atttaggagc cgttcgtgac ggatttttaa cagcgatgcc agctatttta ttttcaagca
    18421 ttttcatttt gattgctgcg gttcctgaga tttttggtta ccaatggcct gaatctgtct
    18481 ccacatggct atggaaagtc tataattatt cgatgggtgt tgtagggtta ctcgtttcag
    18541 caaccactgc tcgctgcttg gctgattcga tgaatcgtcg cttgccgaaa aacaaagtaa
    18601 tcaacaccac ctctgtgatg ctggcctctg tggtaagttt cctgttgtta agcgtctctc
    18661 cgattgaagg tggattttca acggaatata tggggacaaa gggactactg gcttcctttg
    18721 tcgctgcatt tttaacagtt aatttatata agttttgtgt gctgaaagat attaccatta
    18781 aaatgcctaa agaagttcct ggaacgattt cgcaaacctt ccgagatatt tttcctttct
    18841 ctttttcagt atttgcggcc gttttaattg atttaggcat tcgacaaatc ttccaaatct
    18901 catttgcaga agcaatcatt acggtgctgc agccgctatt tacagcagct gacgggtact
    18961 taggaatcgc tattatctgg ggagcgatgg cgctgttttg gtttgtcggt gttcatggac
    19021 cgtcgatcgt ggagccggca attgcggcaa ttatctatgc caatgtggaa accaatctgc
    19081 aattgttcaa ttccggtgaa caagcttcta aagtactgac ggtgggttta gggaattttg
    19141 taggaactat gggaggaact ggggcaacat tggttgttcc ttttatcttc ctactctttg
    19201 ctaagtctaa gcagttgaag gcagttggga aagcttcctt tattccagta agtttcgctg
    19261 tcaacgaacc attgctattt gcggcaccca tgattttgaa cccttatttt tttattccat
    19321 ttttgttaac acctgttgta aacgtttgcc tgttcaagtt ttttgtcgat gtattgggca
    19381 tgaacagctt tatgtacgtt ttgccttggg caactccagc accgatcggt ttggttctag
    19441 gaacgggcat gggtatctta gcttttgttc tagcagcggt tctaatcgtc gttgacttcc
    19501 tgatctatct accattttgc aaagcatacg atgctgtctt agtagagaaa gaagcacaaa
    19561 aagcagaggt gatcgcaacc gaggaaggtg cttctgccga tgtacgtgag gaagtacctg
    19621 tggcagcgag tcaagttatc agcgatgcaa ataaagaaat caatgtgttg gtactttgtg
    19681 ctggcgcagg gacaagtgcg atgttagcta atgctttaaa aaaaggtgca tctgaatcga
    19741 aagcaccgat cagtgcaatg gcgggtgctt atggttctca ttacgaaatg ctgcaggatt
    19801 ttgatatggt ggtcttagca ccgcaagtca attcttacta tgatgatatc aaagaagaca
    19861 ccgatcgctt aggaatcaag ctggttgcga caaaaggagc agaatatatc ggattaacga
    19921 gagatcctga aaaagctgtt cagtttattc tgaaccaatt tcaataaagg aggagccata
    19981 atgaaaatgg gaatttggtt gcgtaaagct gttttatttg cagctgtgtt aggggctttg
    20041 ggggctgttt caaaaactgt tgaagcatct gccagcgaat ttattcgcgg agcagatatt
    20101 tcgatcctgt cagatatgga aaaatctggt gcaaaatatt atgaagacga tatttcaaaa
    20161 gatgccttag agattttaaa aaataatggt gtcaactatg ttcgactgcg tttgtggcag
    20221 gatccttata atagtaatgg agaaagttat ggagcaggga caaatgatct ggaaacgacg
    20281 attgaccttg caaaacgagc aaaaaatctg ggacttaagg tgctgctgga ttttcactac
    20341 agtgattttt gggttgatcc tgggaaacag aatcttccta aagcatggca aggtctgacc
    20401 tttgaagaaa tgaatacggc attgtacgac tatacaaaga acgttctgtc ggaaatgaag
    20461 cagctggacg tttatcctga tatggttcag atcggcaatg aactgaatag cggaatgctc
    20521 tggccttatg gcaagtcttg gggagaaggc gggggagaat ttgatcgatt ggctgctttt
    20581 ttgaagtctg gtatccaagc tgttcgagac actcaaccta aaacaactcc agtaatgctc
    20641 cacttagctg atggtggcga tacaggagca tttacttggt ggtttgatga aatcacgagt
    20701 cgaggtgtgt catttgattt aattggagtg tcgtattatc cgtattggca cggttcaatg
    20761 aatgaacttc aaaccaatat gaatgcgatc agccaacggt atggtaaaga agtgatcgta
    20821 gttgaaacag cttatgggca tacaacagcg aatgccgata ctatgccaaa tgcttttggt
    20881 gaagccgaag cagctgcggg gggatatgaa ccaacaccga caggacaagc agagtatttg
    20941 ctggatcttg ccgatcggat tcaggcagta ccgaataatc gcggggcggg cttcttctat
    21001 tgggaacctc tttggtacaa cggaaatgtg agttgggcaa cacaagcagg tatgaattat
    21061 ctcagtgttc aatccactat gggaaacgaa tgggacaacc aagcgatgtt tgattttgct
    21121 ggaaacgcct tgccaagctt gcgtgcgttt aaacaagcag gggcgcaaat aaatctagtt
    21181 aaaaatgcaa gtttcgaaag cgatggacca acgaccagtc cttccaattg gcaaacctgg
    21241 tttcaacaag gaaccgctaa gggtacgatc aaaacggaag cgggcacttt ttttggggac
    21301 tacaaactaa ctttttggca ggatcaagca tacgaggcat cagcttatca aaatgttagt
    21361 ggcataagca aaggaactta cacattgagt gcctatgtaa tgtctggggg agagtttgat
    21421 actaatcagt tatatatcaa aaattatggt ggagcggaac taaatactgc ggttgttaaa
    21481 acaagtgaat ggacaaaaat tacaatcaaa gacattccaa ttacaacagg tgtttgtgaa
    21541 attggggttt atagcaaggc ttcaggaaat gcttggacga acgttgattt tgtttcattg
    21601 gtgaaacaat agactgcgga tcgtttcgat tcaagatcgg aggttccctt cagccacatc
    21661 gttagcgtag aaggcaggaa tcgaacctgc acctcgcctt tgccaaaaat aaccagaaac
    21721 gatttccagt catttttacc aaaacgagta aagcaccaga cttcatctac actttgtatt
    21781 atgctaaaga gagttcaacg atttcgtaag aagcaatgaa aaaattgcaa aaagttgtgc
    21841 agataacata aagtttgttt aagaaagggt aaccttagaa ttccgtcgtg aatatgattt
    21901 gagcacttag atggatagaa aaaagttctc ggaaaacagt tcgtttttcg agaacttctt
    21961 tttatgataa gaatgaaaca aattaactta tattatagtc tcttttggta gggaaccatc
    22021 ttatttttaa tgaaaatcaa gcattttagc tattgaagaa tgttgattta tagggattcc
    22081 ccctccatat tatgttggct ctttattccc actctgtttt caacgtaaag tgtataaaac
    22141 agaatgcgat actatcaagg gagttaaaac aatatacaga acagtaaaac actataaata
    22201 aaaataaaag tgcaataaaa gtgcaatttt tgcacctaat catactctgt ttatatatga
    22261 aaactagatt ctgaatccaa tatttggtta acgagaggcg ttcgaatttg aacgtctttt
    22321 atatattact ttcaaataaa tatgaggtag aatactatct attttctttt taacccaatt
    22381 gttataatgg agagtgtaaa atattttgtg taaatagaaa aaaggaagtc ccttctgtag
    22441 aatagagtta ccacaacaca ttcacagaag agaggacttc cctatgaacg attttactac
    22501 agaaattcta aagactctag cgaacaaagg cgatttgaat gaattattcc gtgtccattt
    22561 ggagaaagca gtcaatacgc ttctcaaaac ggagttaacg gctttcctag attacgaaaa
    22621 gtatgatcgc attggtttta acacgggtaa ttctcgtaac ggctcctatg accgtacggt
    22681 caagaccgag tatggggaac ttcatctcca gattccgcgc gaccgcaatg gtgagttcaa
    22741 gcaacagact gttcctgctt atagacggac gaatgacacg ttagaggaga ccgtcattca
    22801 cctcttccga aaaggtatta ccatgtcgga aatcgcagac ttgattgaga aaatgtatgg
    22861 gcattactac acgccccaaa ccatgtccaa tataacaaaa tcatttacag aagaggtaac
    22921 ggcgtttaat gggcgggagc ttcatgaccg ttatgctgct atttatatgg acgcaacgta
    22981 tattccgtta aagcggaaaa ccgtcgccaa ggaagctatt catatcgcag ttggcattcg
    23041 cccggacgga tcaaaggaag tattgagcta tgcgattgca ccgactgaat ccatcacgat
    23101 ttgggaggaa attttattgg accttcaaga gcgcggtttg aaaaatgtcc tcctgttcat
    23161 cacggatggc ttaaagggga tggtaggagc gattagtcgg ttctatccca aagctcgttt
    23221 tcaacattgt tgtgtacacg tttcccgtaa tatcagtcat aaagtgcgtg tcgatgatcg
    23281 taaggaagtc tgtgatgatt ttaaaatggt gtatcaagcc tcatctaaag aggtggcgtt
    23341 ggaagcacgt ggtacttttg cggaaaaatg gaaaaccagc tatccaaaag tggttgaatc
    23401 gattctttcg aacgatcact tgctcacttt ctatgatttc cccttggcca tacgcaagag
    23461 tatttattct acgaacttga ttgaatcctt taataaacaa atcaagaaat acagccaccg
    23521 caaggaacag ttccaaaatg aagagtcgat ggaacgtttc ttagtctcgt cttttgatac
    23581 ttacaaccaa aaattcctag gtcgcagtca taaaggtttc caacaggccg aaggcgagct
    23641 cgaacaaatg ctaagccaac tgattgagaa ttagaaacaa tctgcagtag ggaagaatca
    23701 tttacacaaa attattgacg ctcccttata atgagaactt ttactaacat aatttatgat
    23761 aaacttacta tataatcata ttaattaaat agttaggaga tctgcttatg tttatatcta
    23821 ctcttcaaat tcgaaatttt agaaattatg aatccgaaat ctttcgattc gataatgaga
    23881 caaatactat tataggtgag aatgattcag ggaaaaccaa tgctcttact gcattgagaa
    23941 tcttattaga tgatagttat tactatagta gtaaaacact aaaagaatca gatttttttc
    24001 atggaattca aaatgggtgg caagggcatt ggattattat ctctgcgaca tttgaaggaa
    24061 tcagcgaaga agaatttgac aatgagattt gtgcttccat ttctttaaat tctgaaagtc
    24121 aaacaatctt agaagaattg atttcaaatg cagataaagg tgtaggtagt atttctctat
    24181 ttattagacc taacaaagct attagaaagc aattatttga tatttccact gaattagact
    24241 ctcatcaatt taacgaattt agaaattcta ttcgtctatc cgactatgaa ttttactaca
    24301 catctaaatc aaatctaaat ttctgtatca atgaaaatta tgataaattg gtaggaagac
    24361 tcaatgacaa tatagctagt aatcctgaag aagacgatga agctctgttg ggctcaagaa
    24421 ttgacatgtc agatattttc aagcatattt cggttgttta tgttgacgct cttcgagatg
    24481 ttcttagaga aatgaaaaac aatcgaaacc cagtcaaaag aatcatggaa acaattgaat
    24541 caaaaatatc atcagataat gttgagtcat taaaaacaat tatacagcaa ttaaatgaga
    24601 ctattaccag tgttcctgaa attaggaaaa ttggcgaaaa tattaatcgg caactaaata
    24661 gcataattgg ttcagtgtat tctcctaatc ttcttctttc ctcaactatg tcagatgata
    24721 tgggttcttt agcaaaattt ctttcaatga agccagaaca aaatatcgac ttagacttac
    24781 tagggttagg acatctaaat atgatttatt tagctttgaa aatagtcgaa tttgaagcgt
    24841 gtcgttcaag agaactactt aatattatgt tgattgaaga accagaagct catattcatc
    24901 atcatattca aaaaactctg ttcgaaggat taaatcttca aaaaaactat actcagattc
    24961 tcatgaccac acattctgta catttagctg aagtgtctga aatatctcgg atgaatgtat
    25021 taaaatcgtt taatggcaaa tctatcgtta tgaatccagc aaataatctg aactcatttg
    25081 ctaaagaaaa gttaaaaaag aacaatctaa atctaataaa cgcagtagag agatatttag
    25141 atgttaaaag aaatggattg cttttttcta aaggtgttat cttagttgaa ggagatgctg
    25201 aagaaatact tattcctcaa atagtaaaaa aattatttgg tataaactta gacgaacttg
    25261 gaataggttt gattaatgtt ggtagtactt cgtttgaata tatcgctagc ttgtttgacg
    25321 atgatagaat acagagaaag tgtgctattg taactgattt agatgaacag gcaatcccat
    25381 cagaacatcg attgtataaa agcactgcac aagagaaagg tcaagcaaga aaagaaaaat
    25441 tatcctccct ttttaatgaa aacaattggg ttaattgttt ttatgctaat acaacatttg
    25501 aaattgagtt tttagatgtg aataaagaaa atattctaac ttatgtcagt ccaattatag
    25561 atgacgcatt caaagataaa aaaacaataa ctgcttataa agaagaaata caaa
//
LOCUS       DACGMI010000040        25423 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.041, whole genome shotgun sequence.
ACCESSION   DACGMI010000040 DACGMI010000000
VERSION     DACGMI010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.041"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            89..412
                     /locus_tag="IXT46_001868"
     CDS             89..412
                     /locus_tag="IXT46_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947773.1"
                     /translation="MRELTLSSKELEKKTALLNEIFSADCIIQSLKESSFSKLTDQEK
                     ISYMLSLDNLGTKYDESASSDKLLIELVSSLSSFGKMKRFNVILEIFAWLTALGRSRP
                     SSIGG"
     gene            416..565
                     /locus_tag="IXT46_001869"
     CDS             416..565
                     /locus_tag="IXT46_001869"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947774.1"
                     /translation="MPFGMRVTVGNSKTEKINAIISLIPSMMVQFQCEGAQVKDIELA
                     PQVKL"
     gene            896..1096
                     /locus_tag="IXT46_001870"
     CDS             896..1096
                     /locus_tag="IXT46_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947775.1"
                     /translation="MLKRIAWDKDNKTDIELKEYKYNYFSRCIDRKLLFKKEGLEFSF
                     DEDEFEKLVMDWRKNLLDTVQF"
     gene            1230..2456
                     /locus_tag="IXT46_001871"
     CDS             1230..2456
                     /locus_tag="IXT46_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947776.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            3306..4631
                     /locus_tag="IXT46_001872"
     CDS             3306..4631
                     /locus_tag="IXT46_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAQ4947777.1"
                     /translation="MFDYSREPVNDYFLIDMKSFYASVECIERNLDPMTTPLIVMSRS
                     DNTGSGLTLASSPTAKKKYHITNVSRATDLPYPLPKELHIVPPRMNLYIKKNMEVNQI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTSSGTRSERRRELAKIIKDEIQKETGLIA
                     TVGIGDNPLLAKLALDNEAKSSKEFIAEWTYETVPEKIWKINEMTDFWGIGSRMKKRL
                     NHMGIMSIEDLANWNPYTIKSQLGVIGLQLYFHTNGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPKDYTRREEVELVVKEMAEQVAIRIRQHNCKTGCVRLAIGTSILEEKSGFSHQMKI
                     PITDNTKELQNYCLFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEEN
                     LDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            4624..4971
                     /locus_tag="IXT46_001873"
     CDS             4624..4971
                     /locus_tag="IXT46_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947778.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
     gene            5258..5407
                     /locus_tag="IXT46_001874"
     CDS             5258..5407
                     /locus_tag="IXT46_001874"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947779.1"
                     /translation="MPFGMRVTVGNSKTEKINAIISLIPSMMVQFQCEGAQVKDIELA
                     PQVKL"
     gene            5785..6606
                     /locus_tag="IXT46_001875"
     CDS             5785..6606
                     /locus_tag="IXT46_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAQ4947780.1"
                     /translation="MGLLVPRANTYTIPLTKRQLIAKRYQRITRAINREFWNSESDTA
                     HSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQVIKNAFQEILPN
                     SDIRADGQVVKINFHDGIKFEIVPAFNEKDYLGESKGFIYPDSNMGGNWKATNPKKEQ
                     EAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEAMGNWKFVENNSG
                     GQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICLEKVLKKIAL"
     gene            6626..7186
                     /locus_tag="IXT46_001876"
     CDS             6626..7186
                     /locus_tag="IXT46_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HAQ4947781.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNKTHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            8094..8861
                     /locus_tag="IXT46_001877"
     CDS             8094..8861
                     /locus_tag="IXT46_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAQ4947782.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            8887..9432
                     /locus_tag="IXT46_001878"
     CDS             8887..9432
                     /locus_tag="IXT46_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947783.1"
                     /translation="MGERTQALITVKYGNSKTKVSVSIHYQWGYGRFMLMDVLNQGIY
                     LINKAYDLRDESREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            9433..9999
                     /locus_tag="IXT46_001879"
     CDS             9433..9999
                     /locus_tag="IXT46_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947784.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTIEGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMETENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGTDDCVAYYTTAE"
     gene            10014..10262
                     /locus_tag="IXT46_001880"
     CDS             10014..10262
                     /locus_tag="IXT46_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947785.1"
                     /translation="MEGMDFIDHEDLIDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDNTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            10281..10520
                     /locus_tag="IXT46_001881"
     CDS             10281..10520
                     /locus_tag="IXT46_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947786.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEELLRKAKQKGYPDKMLKQIGYYM
                     PEERIEKESCKVLFDSEQLLVLLTQNKLICQFENN"
     gene            10537..11121
                     /locus_tag="IXT46_001882"
     CDS             10537..11121
                     /locus_tag="IXT46_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947787.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEENMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEPELILERQRILFSEQDSKRLYGLYDLQLKGLKAQYV
                     ADSYDDMVEQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSKVES"
     gene            11228..11509
                     /locus_tag="IXT46_001883"
     CDS             11228..11509
                     /locus_tag="IXT46_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAQ4947788.1"
                     /translation="MKVKNPKEKSRIQVGIDKDLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTMDKPVDVLDTDEKLEEWFNEA"
     gene            11499..11840
                     /locus_tag="IXT46_001884"
     CDS             11499..11840
                     /locus_tag="IXT46_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4947789.1"
                     /translation="MKPNEIVTVYAAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     NKSDQIKRVYFPIAEWEKVGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSAIDTKKL
                     NRFIERLQRKV"
     gene            11956..13275
                     /locus_tag="IXT46_001885"
     CDS             11956..13275
                     /locus_tag="IXT46_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HAQ4947790.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQSWSAVVANDMFKVTHRHVIFT
                     INEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKR
                     FINLNEALRPKSWEERITEEFGENPLECSCCGEYYEFVGMSVRKNGRLVIKYAKDNHA
                     KRFMREENRKIDQKEFRQQYEEEKEKTFKAIRWDWERQREIYMSKLW"
     gene            13731..14462
                     /locus_tag="IXT46_001886"
     CDS             13731..14462
                     /locus_tag="IXT46_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4947791.1"
                     /translation="MENSFKNKALYHQLVDLLKKRMESGMIPHDKLPSERELTAQYGV
                     SRTTVRLALQELENTGYIYRRHGKGTFVSDIKTAAADLAGAYSFTEQMKSLGRHPETR
                     ILSFEKMEADKFIAQRLNLPLGEAVFKLSRLRIADREPLMIEDSYLPVKFFLSLDDQL
                     LRSKPLYDLFSEDFKQTVRLADEELYASIASKDDAKQLMIPEGAPVLHLVRQTYNMKN
                     EIIEFTLSVARADQFHYQIRHIRNS"
     gene            14475..15647
                     /locus_tag="IXT46_001887"
     CDS             14475..15647
                     /locus_tag="IXT46_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4947792.1"
                     /translation="MFTIEKEKLEQMGAEITTREIRQQPELWKETIDLYQSAQGELEN
                     FLTEVQKQAKGQRTRVIFTGAGTSQYVGDTLVPYLRKHGDRQAFSFESIGTTDIVAEP
                     EEYLIKEEPTLLVSFARSGNSPESLAAVEIANQVVDTIHHLSITCAKEGKLAQISQAD
                     SKSFLFLMPVRSNDDGFAMTGSFSCMTLGALLTFDQTALEEKQNYVETLNALGNEVIA
                     REHDIEEIVALDFERIVYVGSGSLAGLTREAQLKILELTAGKIATVFDSSMGFRHGPK
                     SFINEKTIMFGFVNNDPYTRDYDLDILEEVHEDEIASGVFAITQPGKRNFSGDTFEFA
                     TGTSLLPDAYLALGYVMVAQTVALLTSVKVANTPDTPSPTGTVNRVVKGVTIHDYK"
     gene            15670..16677
                     /gene="lacD"
                     /locus_tag="IXT46_001888"
     CDS             15670..16677
                     /gene="lacD"
                     /locus_tag="IXT46_001888"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAQ4947793.1"
                     /translation="MLTLTTGKKAAMDRLSTKDGIISALAIDQRGALKKMIKALNVEP
                     TDKHIEHFKELVSSELTPYASSILLDPEYGLPAAKVRHADAGLLLAYEKTGYDATTPG
                     RLPDLLADWSVLRLKEQGADAIKFLLYYDVDEDPAINHQKHVFVERLGSECAEEDLPF
                     YLELVSYDAQISDAGSFDYAKVKPHKVNDMMKEFSKPQYKVDVLKVEVPVNMNFVEGF
                     GTGEIAYTKEEAANYFLEQSQATDLPFIFLSAGVSTELFQQTLVFAKEAGSTFNGVLC
                     GRATWKNGVKPFIESGEAAARDWLQSEGRENIESLNNVLKQTASSWHDKVQVVEEAAV
                     N"
     gene            16689..17630
                     /locus_tag="IXT46_001889"
     CDS             16689..17630
                     /locus_tag="IXT46_001889"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HAQ4947794.1"
                     /translation="MIVTVTMNPSIDISYPLEKLKLDTVNRTDQVSKTAGGKGLNVTR
                     VIHDLKGDVLATGVLGGFHGAYISEELKKADIKQAFTAIQEESRDSIAILHEGNQTEI
                     LEAGPTVSEAEQQAFLENFQELVKEAEIVTISGSLAKGLPLNFYQRLVQLAEEQVVKV
                     LVDTSGESLRQVLAGEHKPFLIKPNLEELEALLGQPFSIDDLEALQRALAQPLFTGVE
                     WIVVSLGKDGALAKYRDSFYRVTIPTIKTVNPVGSGDATIAGFAYGLSQKMSVTELLK
                     LCMAAGMANAQEERTGHVNPANVDMHFEEINVKKIEQ"
     gene            complement(17648..18358)
                     /locus_tag="IXT46_001890"
     CDS             complement(17648..18358)
                     /locus_tag="IXT46_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4947795.1"
                     /translation="MVIPKYQIIKDELKQQIISGKFENGDKFYTEAELAEMFSVSSIT
                     VIRALNDLVKDGFIVRHQGRGSFVSRARKGKIVEFSDIELFPISNDQVQVLSITRGND
                     PVYLSKLELPDTAFYYCIKRLRKAEETPYIYQQTYLPEQYVNPNYQELSYYNSIYQRF
                     KLDYNIHMNEEDFTETNEIKFPTPSDAAKLLEISADEPTVLQVRVTKRRDTQQMLEYV
                     ESYKKWNFYKIELVSKNN"
     gene            18529..20307
                     /locus_tag="IXT46_001891"
     CDS             18529..20307
                     /locus_tag="IXT46_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HAQ4947796.1"
                     /translation="MKTFEIKEDFLLNGQPFKIMSGAIHYFRIDPADWYHSLYNLKAL
                     GFNTVETYIPWNLHEPKKGEFHFEGILDLERFLSIAKELELYAIVRPSPYICAEWEFG
                     GFPAWLLNEDTRIRTNEIGYLKHVADYYDVLIKKLVPHQLSNGGNILMIQIENEYGSY
                     GEEKDYLRSVRDLMINRGITVPFFTSDGPWRATLRAGSMIEEDILVTGNFGSKAEENF
                     ASMQSFFDEHGKKWPLMCMEFWDGWFNRWKEPIVQRDAEELAEAVKEVLIRGSINLYM
                     FHGGTNFGFMNGCSARGVIDLPQITSYDYGAPLNEQGNPTEKYFAIQKMIHDTFPEIQ
                     QMEPLTKNTMEVKGIPLRNKVSLFSTLDTISQPVKTTYPETMEMLGQNTGYILYRTSI
                     KKDAEEERLRVIDGRDRSQLFLNQKLQATQYQTQIGEDIIVPMTEETNQLDILIENMG
                     RVNYGHKLFADTQNKGIRTGVMADLHFLTDWSQYCLPLDSCEAVDYSREWQPEQPSFY
                     RYEVVLDEVEDSFIDLSNFGKGVVFVNQVNIGRFWEVGPTLSLYIPKGLLKEGNNEIV
                     IFETEGTFQPEIQLVKKPLYKEMKEG"
     gene            20310..20789
                     /locus_tag="IXT46_001892"
     CDS             20310..20789
                     /locus_tag="IXT46_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HAQ4947797.1"
                     /translation="MSIIGVRIDGRLIHGQVANLWTTKLNITRIMVVDDEVAQNDIEK
                     SGLKLATPAGVKLSVLPIEKAANNILAGKYDSQRLLIIARKPDRLLKLVELGVPIEEI
                     NVGNMSQTDETRSITKSINVVDQDVEVFNQLHAKGVRLIAQMVPSDKAEDFMNLLAK"
     gene            20802..21698
                     /locus_tag="IXT46_001893"
     CDS             20802..21698
                     /locus_tag="IXT46_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4947798.1"
                     /translation="MDILWWQILLLTLYAGYQILDELQIYSSLSAPVFAGLFAGLVMG
                     DLKAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSVALGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDKLVEDMNYKGIERNFLMGAIPWSFSRMIPVFLAL
                     AFGGGLVEKVVAVLNGDLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHFPYLILGFT
                     LTALLGTVFTNMQVLGTGVAGVVKNFEGIFNSLPMLAIALIGFALAAISYKNGQMIPN
                     SPAPKEVASNDSDEGEIEDDEI"
     gene            21685..22494
                     /locus_tag="IXT46_001894"
     CDS             21685..22494
                     /locus_tag="IXT46_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4947799.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDDTPELKEIMKTHTQFFNTSNFFNTIVTGIDLAIEEKEGIGGKDTVSGMKA
                     GLMGPFAAIGDSIFAALIPTIFGALAANMAINGNPTGIFIWIIAQIAVMIFRWKQLEF
                     AYREGISLVTTMQHRLTALTDAATLLGVFMVGALVATMINVKFSWAPSIGDVTLNMQN
                     NLDMILPRLLPAGIVAAIYWMLGKKNMTSTKAIFIVLVVCVALSVLGVISK"
     gene            22532..22936
                     /locus_tag="IXT46_001895"
     CDS             22532..22936
                     /locus_tag="IXT46_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4947800.1"
                     /translation="MGKQLVLVSHGLFCEELKKSTEMIMGPQESIHTVSLLPAESAED
                     FRAKFEAVIADLDDFVVLADLMGGTPCNVVSRMILEGQAIELYAGMNMPMVIDFINSE
                     LIGTELALVESATSNICHVNERIIGDDDDEDE"
     gene            23080..23673
                     /locus_tag="IXT46_001896"
     CDS             23080..23673
                     /locus_tag="IXT46_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4947801.1"
                     /translation="MDFNEKLKQLRQNRQWTQEELAERLFISRTAVSKWESGRGFPSI
                     DSLKAISQVFDISIDELLSNSELLSIAENEQQQQRKNFQHLLLGISDCMVGLLIVLPI
                     FGQAQGNHIAFVSLWQLSQETIIFKLIIFSFVILTMLFGIFELAFSRREQRIIGSVSL
                     ILSLFGVLLFIMTRHPYPATYVLMLLAVKGISLLNSR"
     gene            23782..24459
                     /locus_tag="IXT46_001897"
     CDS             23782..24459
                     /locus_tag="IXT46_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAQ4947802.1"
                     /translation="MKIAKKQLETAIGLLIVFILYTISLSLFDVQKIGPQHSEVGFST
                     INQYVFQKIGTSEFWYQVTEILGIFPLIIVGYFALRGFFQLYTRKKLLLVDKEILALG
                     FLYAGVAACYVLFEKVIINYRPILVDGQLEASYPSSHTFLAITVLLSAFYVLRKETGT
                     GKAIIAYVSLVVMIALVIGRFLSGAHWGTDIFGGILLGLTLASCYLAGIESSSKQKKR
                     TLKTQRS"
     gene            complement(24463..24535)
                     /locus_tag="IXT46_001898"
     tRNA            complement(24463..24535)
                     /locus_tag="IXT46_001898"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24500..24502),aa:Thr,seq:ggt)
     gene            complement(24653..25030)
                     /locus_tag="IXT46_001899"
                     /pseudo
     CDS             complement(24653..25030)
                     /locus_tag="IXT46_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         8776 a         3879 c         5455 g         7313 t
ORIGIN      
        1 caattaaacg tatttacgat cttttatcac ttatataaag agagaagtga taaataggac
       61 acaaaatttg gaaagtaggt aagtcactat gagagaacta actttatctt ctaaggaatt
      121 agaaaagaaa actgctttat taaacgaaat atttagtgct gattgtataa tccaaagttt
      181 aaaagaaagt tcattttcaa aactaacaga tcaggaaaaa atttcttata tgctaagttt
      241 agataatcta ggaactaaat atgatgaatc agcaagtagc gataagcttt tgattgaatt
      301 agtatcaagt cttagtagtt ttggaaaaat gaaaagattt aatgtgatat tagaaatttt
      361 tgcttggtta acagcattag gcagaagtcg cccatcctct ataggtgggt gatgaatgcc
      421 gttcggtatg agggttaccg ttggtaactc gaagaccgaa aagataaatg ctataattag
      481 tttgattcca agcatgatgg tgcaattcca gtgtgaaggc gctcaagtga aagatattga
      541 gttagcgcca caagtaaaac tgtaagactt gaagacattc gtgacgatgc gagtgtaaca
      601 atgattatga ttagagtgaa aaacaaactg aatctgtcat aacgttgtgt ggttagtatt
      661 tcgaccgacg ataaaaataa atcaaaaaaa ccgtaggaac tacggggata gcttggtaaa
      721 taagagaaac cgctgttagt gaagaaataa gctatcaagt atgctctatt cccaagaagc
      781 tcccacttca agtgttaaga accgttaggt ttagctaagt ggtgagtagt tcactaactt
      841 gtatacacgt attcaaataa aaaagcagtt attacatgaa ggattaagtg gtaatatgtt
      901 aaaaagaatt gcatgggata aagataataa aacagatatt gagcttaaag aatataaata
      961 caattatttc tcgagatgta tagatagaaa gttactgttt aaaaaagaag gattagaatt
     1021 tagttttgat gaagatgaat ttgaaaaatt agtgatggac tggcgtaaga atttactgga
     1081 tacggtacaa ttctaaaagc aattgaggtc gaaattccga tacttgaatc atgatctata
     1141 ttatcgtgtt atgagtgaaa tttctaataa agataagata tttcatttgg acagtcatgt
     1201 gaatatgagc ttaacaatta aacgtattta tgatctttta tatgtttata aacattaatg
     1261 aggtgctaaa attgacaaca ataactatga caaaaaaaat agaagtatat gttgatggat
     1321 cacaagaaga aagggattcc ttttttgatt ttttttggaa aaatagtaga gaatatgtaa
     1381 aagcgttgaa tctggtatat aaacagctaa tgtttgaaga gttgataaaa gatgcaatta
     1441 aagaaatgga tcaaggttat gctgagagag aagaaagtat tcaaaatcgg attgaaaagt
     1501 tagcatatac tgatccaata gatcaaaaaa aacttgataa agcaaaagct gaattatcta
     1561 aattgagaaa tgaaaaaaat aaagaagcga gagaaatatt aacgcaagcg atagggttga
     1621 agagtcaaac gagaacacga gatgtagcaa aaaaattaga ctttgacttt ggagattttg
     1681 ttgattccgc aaatatgaaa gctagtaaag attttggcaa tgattttatc ggaattgtga
     1741 ccggacaaag aacgcctaga atatataaaa atagaaacaa atatggatta ctacctttta
     1801 gaggtcgaga tattaaaatc cataaagatg ataagtttta tatttattta cctaaaggct
     1861 ttaggtttaa agtgaattta ggtagcaagc caagaaaagc aagagatgtt gcttcagttt
     1921 tacaacacat tatggatggc gattacaaat taaatcaaag taatcttatt tttgatggaa
     1981 gaaaattatt ttttaatcta acaatttctt ttgaaaaaag ctataatgaa atggaattca
     2041 agaaaggtaa tgaattgatc gtaaactttg cagatttgtg tagcggtgaa tgtttaatta
     2101 atgataaatc tgtaatgtct tttggtgata gccaatatat aagaaacttc aaaagtaaaa
     2161 ttttagcaat gaaatcaaaa gaacaaagcc gaggagtctt ttctaagggc ggtcatggtc
     2221 gaaaaagaaa attagatcaa gatcgatggg aagcaataaa gaaaagagaa agtaattttg
     2281 ttaaaactta taataatcaa tgttctgcaa aaatcgttaa aactgctatt cgcaataaag
     2341 ctcaaattat tcgtatcatt gaaccagata aggcttatgg cgaatgggct tactatcaat
     2401 tgaaagaaca actagtaaac aaaggaaaaa gatatgggat agaagtcaga agttagtaaa
     2461 ttaaacaatc gttgatttgg caacgaaata gtgagggaaa atccactcac tgaagggtaa
     2521 actccgtcaa gttgtgtgac cagacggaag gacgaatgtt gttgaggttt tagaaccata
     2581 taaaacagca tgtttctcaa atttttagga taagggaaat tgctagcagt ttgttttaga
     2641 accatataaa acagcatgtt tctcaaatga gtactttaaa ttaattgatg gcgttcctgc
     2701 tttagaacca tataaaacaa catggattta aaacaagaag taagtcagtt ctccttttac
     2761 tttagtaagg aaaaataaag tattctcaat aaaacttaaa ataagcaaac ctttgtttta
     2821 atagctaatc gaagtaaaac ccaaagccat atgaacccct gaatcagcga aagtttatga
     2881 tgatttggat tactaatagt ttaggaatta gatggtaaat ctaaattaaa caatcgttga
     2941 tttggcaacg aaatagtgag ggaaaatcca ctcactgaag ggtaaactcc gtcaagttat
     3001 gtgaccagac ggaaggacga atgttgttga ggttttagaa ccatataaaa cagcatagtt
     3061 ctcaaattgt ttaaaatgat tgtcaagtta aaaaaatctg ggatcatata aaatagtata
     3121 gttctcaaat atgattagaa accctattaa agagcaatat taagccaact tacttaaatc
     3181 gtttaattaa gaacaataat ctcttttagt cagactttta gtctgacttt tttgtatttc
     3241 caaaatttat tctttacaaa aacgaacata cgtttgtata attgcttgtg aatgggggaa
     3301 taaaaatgtt tgattacagt agagaaccgg tgaatgacta ttttttaatc gacatgaagt
     3361 ctttctatgc tagcgtggaa tgtattgaac gaaatttaga cccaatgact acaccgttaa
     3421 ttgtcatgag tagatcggac aacactggtt caggtctgac tctagcttct tcacctactg
     3481 caaagaaaaa atatcatatt actaatgtta gtagagctac tgatttacct tatccattac
     3541 caaaagaact tcatattgtt ccaccacgaa tgaacttata tataaaaaaa aatatggaag
     3601 ttaatcagat ttttagaaag tatgtcgcag atgaagattt attgatttat tcgattgatg
     3661 aatcaatttt aaaagtgaca aaatccttaa atttatttac tagttcagga acaagaagcg
     3721 agagaagaag agaattagct aaaataatca aagatgagat tcagaaagaa acaggtctaa
     3781 tagcaacagt cggaatagga gataacccat tattagctaa acttgcactg gacaatgaag
     3841 cgaagagtag taaagaattt atagctgagt ggacttatga gactgtacct gaaaaaatat
     3901 ggaaaataaa cgagatgact gacttttggg gcattggatc acgcatgaaa aaaagattga
     3961 atcatatggg aattatgagt atagaagatt tagcaaattg gaatccctac acaattaaaa
     4021 gtcagttagg tgtaatcgga ctccagttat atttccatac caatggaatt gatcgtacgg
     4081 atattgctat tccaccagaa ccaaccaaag aaaagtctta tgggaattca caagttctac
     4141 caaaagatta tacgaggaga gaagaagtag aactagtagt caaggagatg gcagagcaag
     4201 tagccattcg aattagacaa cacaattgca aaactggttg tgtacgctta gcaattggta
     4261 cgtcaatttt ggaagaaaaa tcaggtttct cgcaccagat gaaaatacca attacagata
     4321 atacgaaaga attacaaaat tattgtcttt ttttattcaa taagttttat gaggggcagg
     4381 aagtacgaca tataggagta acttatagca gattagtata cacagattcc ctacaattag
     4441 atttatttag tgatccaaga aaaaagattg ctgaagaaaa tttggatagg attattgata
     4501 agattagaca aaaatatgga tttacagcta ttatacatgc ttcatctatg ttagaaggtg
     4561 caagaagtat tacgagaagc actttaatag gaggacacgc aggaggatta ggaggtttgc
     4621 ataatgattg aatataacga tagaggacgt ttaaaatggt cgggatttta tttgtctgat
     4681 catactgaaa gaatcaatgc agacaatgta caacgtgcta atcataattt ggcaaaagaa
     4741 caaatgacga ctgaagagat tgcgaaaata ctgagaactg ctgtcataaa aaatagaccc
     4801 gtctgcattc aaaaagagga acgaaacgct gaaggttact atccagatga tgtagtagga
     4861 aaaattattg gatatgacga gcttggtgta tttgtggaag aagaaaaagt tcactatgat
     4921 gaaattagga atgtttcttt ctcggaatta ttaaaatgga gtcagatatg aacattatta
     4981 aaaaatacga attcggttat attacgtatg aacagctaat agaggaatta tggggatatg
     5041 gtcaacaatt aattaatgaa gtggggattg attgcttttg tttctatatt gaatccggag
     5101 caggatacca taagaacaga tactatatat ttccatatcc accaaaatag tctcttagat
     5161 atttttaaat tttctccaaa tactttcaat tattgtgaaa tatttccctt taacagcatt
     5221 aggcagaagt cgcccatcct ctataggtgg gtgatgaatg ccgttcggta tgagggttac
     5281 cgttggtaac tcgaagaccg aaaagataaa tgctataatt agtttgattc caagcatgat
     5341 ggtgcaattc cagtgtgaag gcgctcaagt gaaagatatt gagttagcgc cacaagtaaa
     5401 actgtaagac ttgaagacat tcgtgacgat gcgagtgtaa caatgattat gattagagtg
     5461 aaaaacaaac tgaatctgtc ataacgttgt gtggttagta tttcgaccga cgataaaaat
     5521 aaatcaaaaa aaccgtagga actacgggga tagcttggta aataagagaa accgctgtta
     5581 gtgaagaaat aagctatcaa gtatgctcta ttcccaagaa gctcccactt caagtgttaa
     5641 gaaccgttag gtttagctaa gtggtgagta gttcacttaa tcaaattttt tataaaagta
     5701 atatataaaa taaattgctt gaagtattat atttagatat cataatttat ggaagaaaaa
     5761 ttaattaaaa aggatgagat tataatgggg ttactggttc cgagagctaa tacttatact
     5821 atacctttaa cgaaacgcca attaattgct aaaagatatc aaaggattac tagagccatc
     5881 aatagagagt tttggaattc tgaaagtgat actgctcaca gtttatacgt aggttcttat
     5941 gggagaggaa cggcaattag tactagtgat atagatataa tagttgaatt accgatggca
     6001 gaatttgaca gattcaaaaa ttatttatca aatggaccgt ctaagttatt acaagttata
     6061 aaaaacgcat ttcaggaaat actaccaaat agtgatatta gagctgatgg acaagttgtt
     6121 aaaataaatt tccatgatgg aatcaaattt gaaatagttc cagcttttaa tgaaaaagat
     6181 tatttgggtg agtcaaaagg gtttatttat ccagattcaa acatgggagg gaactggaaa
     6241 gctacaaatc ccaaaaaaga gcaagaagcc atgaaattaa agaatacaaa aagtaataat
     6301 ttattatatg ctacgtgtaa acattttcga catgtacgag atacagaatt tacgagttat
     6361 catctttcag gaatagtaat tgacagtttc gtatatgagg ctatgggaaa ttggaaattc
     6421 gttgaaaata acagtggggg tcaaaacatt agttctgtat cttatgagac agctttatta
     6481 gaatactata actcacataa agttatgggc ggtttaaatt tatactctcc tggaagcaat
     6541 caatttgtta attctgatag tagtatcata tgtttagaaa aagtattaaa aaaaatagct
     6601 ttataaagtt ttatggagga acaacatggg agacgaaaaa aagcgcttgg aagttcaatt
     6661 acgtgaagca tatggacgag taacgtatac ttacaccact catttaaagc aagccgataa
     6721 tattatttct gacaataaaa ttttaaggtg tcttcaaatt ggtttgtcag cccttactac
     6781 tggaggggta cttagtacca ttattactga taatagtgag ttaacctttg ttgctggatt
     6841 atgttcaaca atttctcttg gattaaactt atactttaag aattttgatc ttgctgaaga
     6901 agctaaaaat catcaaattg ttgccgataa attatggttg atcagagaag aatacgtaag
     6961 cttactaaca gatttaaatc gtttaagtgt tgaagatatt gtgaaaaaaa gagatcaatt
     7021 aatgaacaaa actcatgaag catataaaaa tgcccctaaa acaaatagta aaagctatga
     7081 atcagctcag aaagcattaa aatctgaaga agagcaattt tttacagaag aggaattgga
     7141 taagatgtta ccagagcatc ttagaaaaaa gagttctaaa tattgaactc tttttttatg
     7201 cttaaaattt tcttgtaatt tttctattca atcaataaat aatctatatt taagaagaaa
     7261 tatgatgata gaaacatctc ctaaagccac cgcaagccgt cctagccatt gcccagtccg
     7321 acatcgctag attagtgcat ctctccaaaa aagttttcta aagccaccgc aagccgtcct
     7381 agccattgcc tagtccgaca tcgctagatt agtgcatctc tccataaaag ttttctaaag
     7441 ccaccgcaag ccgttctaag catagcttag cccgacattg ctagatatgc tcatctcacc
     7501 atgaacgttt cctaaagcca ccgcaaaccg tcctagccat cgcctagtgc ctagtccgat
     7561 tttgcttgat cggttccatt tctgtttatt tagtgggtca acaccgtaat cttaaatagc
     7621 catcgcctat ttaagattac taggtctgct ttgaaggtaa aaagtctttc attcttcaag
     7681 acttttaggc tttcaagcta cgcctgaaag cattgaaatt catcgctctt tatttggttt
     7741 tgccatttat aattccttac gcccattatc tttttcgcct gtcatacctt gtcagaagtg
     7801 tttagagctt atctcatctt tggattaata caagtggcgt aaattttttt ctaaacgcaa
     7861 gcgttacgaa aataatttac ttaaacactt gtattaatcc ggcagataag aacgcattct
     7921 aatcactccc gacaaggcaa gacaggcgaa aaagataaat aaatgaacga aaggaagaaa
     7981 cataaaatgc aaaaccaaat agcgatgaag aaaaaaccac ctccctctaa aacaatccaa
     8041 acaaaaaaga attttgaaaa accaaaaatc aaaaacagaa agaagcgttc aacatgagag
     8101 atagaatttt agaagttaat caagaaatgg taaacaagtt aacaaatatc agtgggaact
     8161 atgaaaagta cgatggtact ttacttgata attatatttt tcacgataca caaaatatca
     8221 gaattggcag aagtaaaccg agagcgttca ttctcatcaa agagaaatat ttgaatgaat
     8281 ggaatagcac ctatgaaatg gttatgactg ataactttga aaaggtattg gatttcagaa
     8341 atgctttgtt gggttctgat atgggaaata gcagtcttga atctattgaa gttgaaaaca
     8401 agaccgagaa tgaaggtgaa ggattgatta agaatgtcct gaaaatcgaa caaaaatata
     8461 tcagtgaaga tagaagtttt tatagagtca caagctcggt tggtctagca aactttgcta
     8521 ctaacttaat tggaaacaat gctagtgaat ctttgctagt gatgtgtctg aatacaaaga
     8581 atgaggtcat tgcttatagc gaagttttca aaggtggaat taatcaatca gtagcgatac
     8641 caagagagat ttttcaacta gctttgctaa acaattcagc aaaaatcgca gtatcacata
     8701 atcatccgag cggatatgaa tttccaagtg aaaatgacaa aagttttact acgaatttga
     8761 aaaacgcagg aaaaacaatt ggtattgaat tgttagacca tatcatcgta acaagtaaaa
     8821 acacaagcta ttactcattt caagaaaatg gttctttata aaaattagag aaaagaggaa
     8881 aacaagatgg gcgaaagaac acaagcgtta attacagtca aatatggtaa cagcaaaacg
     8941 aaagtaagcg tgtcaattca ttatcagtgg ggatatggtc gattcatgtt gatggacgtt
     9001 ttgaatcaag gaatatattt aatcaataaa gcatatgact tacgagatga atcaagagaa
     9061 gaattagcaa aaggaatctt tgatagaagt acaggagtta tcaattttgt cacctatgaa
     9121 tctggagtga gtgcttatga tgaaacaggg tttggtgggc gctatgaacc ttatcaagaa
     9181 acgattgaag atgtgatgaa gttttcagat aacaatgatg gctatgctca tttagagatg
     9241 gtgttcgatg aaaatggatt tagtctagat gataaaacca gattgcgatt gtttgatttt
     9301 gagggtcaac agataggact aaacaagttt tgtgaaagcg gaaaagagtt tgctacgaaa
     9361 gattttatta agggatacag attattgcta gaaaattatg gaataaacct agaagaagag
     9421 agcgtgaaat aagtgtttga aaaaagaaaa gaccagttcc ctaatttaga agcgaaaagt
     9481 caaaaagtga ttgatggtga aatgattgaa ttattccaaa aaagttatgg aaccatagaa
     9541 actaccgcaa gttgcaaata ctactttcaa ggaaagagaa acacgtttaa aggctttgcc
     9601 gattctgatg aagaattggc aaagaaaatc attgattggc ttgtcagcag tgaacacgta
     9661 gcaagagaag ataccgttag aacaacgatt gagggtgaag tcctaacagg tactagatgt
     9721 gtttgttgta atcatgaatt tgtagaagat gaaggttgct accgaatcaa tgaatatggt
     9781 gattttattt gccagagttg ccacgagata gaatttccaa ccgaaagaag ttggtttgaa
     9841 tacatgctac aagattatga gatggaaaca gaaaatggtg aagtagtttt ttgtaccaaa
     9901 gaggaattga gtaagagaag cgatgatgaa attgaagatt ggtgtgtgtg gttagtaggg
     9961 acagatgatt gcgttgcata ttacacaaca gcagaatagg agtgtgaatc agcatggaag
    10021 gaatggattt tatagatcat gaagatttga ttgattttgg ttatacatgg aaaggaatgg
    10081 taggtattag cagaagtctt gctaatgcct tttacgaaag aaattatgca gtctatgtcc
    10141 tttatgatga caatacagaa agccttgttg atgaagagta taaattggat ttagagaatg
    10201 ttttatatgg gatagaaaaa gaagatttag caaaatatat tttttcatgg ttgggtcaat
    10261 aaacgaaaga gggtagcaac atgacaaaat tcaaaagtaa aggtatgcaa tggtgttctt
    10321 attattatgt tgggaatgat gaagagcttt tgagaaaagc caaacaaaaa ggttatccag
    10381 ataagatgtt aaaacagatt ggctattaca tgccagaaga gagaatagaa aaagaatctt
    10441 gtaaggttct ttttgatagt gaacagctat tagttttgtt aactcaaaat aaattgattt
    10501 gtcaatttga aaataattaa tatggggtga agaaccatga atgagaataa gatggtatta
    10561 agtgaatacg caagattgag aaccattaat tggttgaatg gtatgcaaag tagtggcgct
    10621 tttgatggat ttgatgagga gaatatggac tttgaaagtt tatcgaatga ggatattaga
    10681 tattatttta tcgaatggta ttttacagaa ccagatgaag aggtggaaga tgaaccagaa
    10741 ttaattttag aacgtcaaag aattttattc agtgaacaag atagtaagag gttgtatggt
    10801 ttatatgact tacaactgaa aggattaaaa gcgcagtatg ttgctgatag ttacgatgat
    10861 atggtagaac agggggcaga tagggttgtc acttattcag aagatgatga agaggaatgg
    10921 gaaaactatt cagatgatga gatatgcttt aatgatgggt atatgcctat tgaaatcacc
    10981 gaagaagaat atgataaagt gtcggatagc gatgagattg gtatgtgtac ggttgtaagt
    11041 ggattggata tagatgtcca aagagtagag gttgcatacc agaagatgaa agaacgtata
    11101 aaaagtaaag tagaatcttg atttgattgg attgtttgca aagtagctaa ttaagagtat
    11161 aatataatca taaatgtagt taatggatat aataatgagt atattatact caaaagaggt
    11221 gaacgaaatg aaggtaaaaa atccaaaaga aaaaagcaga attcaagtcg gaatagacaa
    11281 ggatttaaaa gaaaacgcag aaatgatatt ggaagagcta gggttaaatc caacaacagc
    11341 aatcacaatc ctttataagc aagtggtcgc tagaggtgag tttccagtag agataaagct
    11401 aagcgaagag gaaaagcaag gaatcagatt gcaacagcta actatggata agccagttga
    11461 tgttctagat acagatgaaa agttagaaga gtggttcaat gaagcctaat gagatagtaa
    11521 cggtctatgc tgcatttaca gataaaaatg gtggtaaaag aagacctatt ttggtggtta
    11581 gtgataaaga agatagagta gaattttttg gaatcacaag tcaatatgag aataaatcag
    11641 accaaataaa gagagtgtat tttcctattg cagaatggga aaaagtaggt ctaaagaagc
    11701 aatcatggat tgacgtaggg tctttaaagg ctattcccaa aagccgagag aacatatcat
    11761 ttaaaaaggt tggtatgcta tcagctattg atacgaaaaa gctaaatagg tttatcgaga
    11821 gattacaaag aaaagtctaa caaggctttt ctttttttga cagtaaagaa agtataaaaa
    11881 gttaagggct aaaaaggctg cactaccagt cttttagccc ttttcatttt gtttttgaac
    11941 aagtaaaata ttactatgaa agcgaatatt ctcgaagcaa tcttttttga cgaacaccat
    12001 aattgggata actttgttga gaaatacggg cgaaagattc ggctagtcgt caaacgggaa
    12061 gtaaacaagt ttagatattg tggagatatt caaaaaggat accgactgtt tgtctgcgaa
    12121 ggatgtcatc aaacaaagtt tgttcccttg aaatgtcgtg gaaagttctg tccaacgtgt
    12181 gcaacaggtg aaagccaaag ttggtcagcg gttgtggcga atgatatgtt taaagtgaca
    12241 catcggcacg taatctttac gatcaatgag gggttacggg aaatctttat gatggaaaac
    12301 tatcgagatt ccttactgaa aggactaatg gatgaagccg caaaaattat tcttgcctat
    12361 tttgagaaaa gaaaggtgaa ggcaggtata gtagctacaa tccacacctt tggatcaaaa
    12421 ctagaattta atccgcatgt tcatatggtt gttactatgg gtggcttaac aagagatgga
    12481 agttgggaag aatacgatta tttacctttt tctatgttaa gaaaatactg gaaaaatgct
    12541 gtattgaaac taattagacg aacgttaggt gagtgggaca agcaaagagt tcaatcaaga
    12601 ttacaagctg cgtacaagaa caatggagaa gggttttacg taaatgctcc taaaaggagc
    12661 aggacaaatc taaagtcact actccaatac atcagtcgtt atatgaagcg tggcccgatc
    12721 gcattaagcc gaatcttaat gtatgatggc gacactgtca tgttcaacta tatggacaaa
    12781 cgaacgaata ctaaagagac gatgaccatg agtatagacg aattcatagc tgcactgatt
    12841 cgccatattc aaaataagaa tttcaaaacg attcgtcgct atggaatcta tagtcgtaga
    12901 atcaaaacat taatgaaaaa ggtcatgaag gagtatcaga aacgagtaaa aaagcggttt
    12961 atcaatctga atgaggcctt aagaccaaaa tcctgggaag aaagaataac cgaagaattt
    13021 ggtgaaaatc ccttagaatg ttcttgttgc ggtgagtact atgaattcgt tgggatgagt
    13081 gtgcgcaaaa atggaaggtt agttattaaa tatgcgaaag ataaccatgc aaagcggttt
    13141 atgcgagagg agaatcgaaa aattgaccaa aaagaattca ggcaacagta tgaagaagaa
    13201 aaagaaaaaa cttttaaagc aattcgctgg gattgggaac gccaacgtga aatttatatg
    13261 tctaagttgt ggtgaaaaag aatcaatccc aatggatgta gtaaaatttt tagatgatgc
    13321 agatattgca aatgatccga acaatcctcc ccaatttacc tgtgaaaaat gtgggaagga
    13381 gatgtatcca gaatattata gaaacgccct tggaatagag tttaagatca gtgatcttca
    13441 ataagaaggt taatcataca aaaagtccac cggagaattc attctccggt ggttttctta
    13501 tgctctaatt gcgtcaactg gtattagatt ttcataccaa ttattgaaaa gtttatttga
    13561 atatagtttg aaagaaaaat tctactagca tattttatct tacgaaaact tgataaaaca
    13621 gcattttaag ccgacagtaa aattactaaa agatttattg ttgacaaagg taaaaaaacc
    13681 accttaccat tgggttgtgg ttataaccag tttaaaagaa ggagaagccc atggaaaatt
    13741 cttttaaaaa caaagctttg tatcatcaac ttgtagattt attgaagaag cggatggaaa
    13801 gtggcatgat tcctcatgat aagctgccat ctgagcggga attaacagct cagtacggag
    13861 ttagtcggac gacggttcgt ttagctttgc aagagctgga aaacacgggg tacatttatc
    13921 ggcgtcatgg aaaagggaca tttgtctctg atatcaaaac agctgctgca gatttagctg
    13981 gtgcctacag ctttaccgaa caaatgaaaa gcctcggcag acatcctgag acgcgaattt
    14041 tatcctttga aaaaatggaa gccgataaat ttatcgcaca acgactcaat cttcctttag
    14101 gagaagcagt tttcaaattg agtcggctgc ggatcgcgga tcgagagcct ttaatgattg
    14161 aagatagcta tctgcctgtc aaattcttct tgtcattaga tgatcagcta ttaagaagca
    14221 agcccttgta cgatcttttt tcagaagatt ttaagcaaac ggtccgttta gcagatgaag
    14281 agctttatgc cagcatcgct tcaaaggatg acgcgaaaca gctgatgatc cctgaaggag
    14341 caccagtcct gcatttagtc cgtcagacct acaatatgaa aaatgaaatc attgaattta
    14401 ctttgagcgt tgctcgcgcg gatcaatttc attatcagat tcgtcatatt cgaaatagtt
    14461 aggagaatta aagcatgttt acaatagaaa aagaaaaatt ggaacaaatg ggagcggaga
    14521 tcacgacgcg tgagattcgc caacagccgg aactttggaa agaaacgatt gacctttatc
    14581 agtcagccca aggggaatta gaaaattttc ttacagaagt ccaaaaacaa gcaaagggtc
    14641 agcgtacacg cgtaattttc accggtgcag gaacctccca atatgtaggc gacacgctgg
    14701 ttccttattt gcgcaaacac ggcgatcgtc aagcattcag ctttgaaagt atcggaacca
    14761 ctgacatcgt ggcggagcct gaagaatatt taatcaaaga ggaaccgacc ttactggtat
    14821 cctttgccag aagcggaaac agtcctgaaa gtttggcagc agttgaaatc gcaaatcaag
    14881 tcgtggatac gatccatcat ttatcaatca cctgtgcaaa agagggaaaa ttggcgcaaa
    14941 tcagccaagc cgattccaag agctttttat tcttaatgcc tgttcgttcg aatgatgacg
    15001 gttttgccat gactggcagc ttctcctgta tgacactagg cgcgttgctg acatttgatc
    15061 aaacagcact agaggaaaag caaaactatg tagaaacatt gaacgcttta ggaaacgaag
    15121 tgatcgcccg tgagcatgac atcgaagaaa ttgtcgcact tgattttgaa cgaattgttt
    15181 atgtcggttc cggcagttta gcaggcttga ccagagaagc acaattaaaa atcctagaac
    15241 tgaccgctgg aaaaatcgcg acagtctttg attcatcgat gggctttaga cacggaccaa
    15301 aatcatttat caatgaaaaa actattatgt tcggttttgt caataatgat ccatacacgc
    15361 gggattacga tttagatatc ttagaagaag ttcacgaaga tgaaatcgct tccggtgtct
    15421 ttgctatcac tcaacccgga aaacggaatt tctctgggga tacgttcgag tttgcaactg
    15481 ggacttcttt acttccagat gcctatttag cactaggcta tgtcatggta gcacaaactg
    15541 tcgcgctttt aacatcggtg aaagttgcga atacacctga cacgccttca ccaacgggaa
    15601 cagtcaatcg agtggtaaaa ggcgtaacga ttcatgacta taaataggaa ttaactggga
    15661 ggaagaaaca tgcttacatt aacaacaggt aaaaaagcgg cgatggaccg tttatcaaca
    15721 aaggatggca ttatcagtgc cttagcaatt gatcaacgtg gggcgttaaa aaaaatgatc
    15781 aaagcgttaa atgtcgaacc aacggataag catattgagc attttaaaga attggtatcg
    15841 agcgagctga caccatatgc gtcttcgatc ttattggacc ctgaatacgg tctgcctgca
    15901 gcaaaagtac gtcatgcaga tgcaggtcta ttgctggcat atgaaaaaac aggctacgat
    15961 gcaaccacac caggacgttt acctgatcta ttagcggatt ggtcggtttt acgactaaaa
    16021 gaacaaggtg ccgatgctat caagttttta ctttattatg atgtggatga agatcctgcg
    16081 atcaatcatc aaaagcatgt ctttgtcgaa cggttaggca gtgaatgtgc agaagaagat
    16141 ttgccatttt acttagaatt ggtttcttat gatgcgcaaa tttcagatgc tggttcattt
    16201 gactatgcta aagtgaaacc gcacaaggtc aatgatatga tgaaggaatt ctcaaaaccg
    16261 caatacaaag tggatgttct aaaagtggag gtcccagtga atatgaattt cgttgaaggc
    16321 tttggtactg gtgaaatcgc ttatacaaaa gaagaagcgg caaactattt cttagaacaa
    16381 agccaagcaa cggatttacc atttattttc ttaagcgcag gtgtttcaac ggagctattc
    16441 caacaaacat tggtatttgc taaagaagct ggctccacct tcaatggtgt gctctgtggg
    16501 cgtgccacct ggaaaaatgg tgtaaagccg tttattgaat caggtgaagc tgctgctcgt
    16561 gactggctgc aaagcgaagg tcgtgaaaat atcgaaagct tgaacaacgt gttaaaacaa
    16621 acggcaagct catggcatga caaagttcaa gtcgtagaag aagcagcggt gaactaggag
    16681 gcgagctcgt gatagtaaca gtaacgatga acccgtccat tgatatttct tatccactgg
    16741 agaaactgaa gctagacacg gtcaatcgaa ccgatcaggt gagtaaaaca gctggcggaa
    16801 aaggacttaa tgtcacgcgt gtcattcatg atttgaaggg cgatgtttta gcaacgggtg
    16861 ttttaggcgg ttttcatggc gcttatatct cggaagaatt aaagaaagca gatatcaagc
    16921 aggcatttac agcgatccaa gaagaaagtc gagattcaat tgcgatcttg catgaaggaa
    16981 accagacgga aatattagaa gctggtccga cagtttcaga agcggaacag caggcttttt
    17041 tggaaaattt tcaggagttg gttaaagaag ccgagattgt caccatttca ggcagtctgg
    17101 ctaaagggct cccattgaat ttttatcaaa ggctcgttca attagcggaa gaacaagtgg
    17161 taaaagtcct tgtggatacc tctggtgaaa gcttgaggca ggtgttagcc ggtgagcata
    17221 aacccttttt gattaagcca aaccttgaag aactagaagc tttattagga cagccgtttt
    17281 caattgatga tctagaagcg cttcagcgtg ctttagctca gcctctgttt actggggtgg
    17341 agtggatcgt tgtgtcacta ggcaaagatg gggcgcttgc aaaatatcgt gattctttct
    17401 atcgagtaac gattccaacg attaaaacag ttaatccagt ggggtcaggt gatgctacta
    17461 tagctgggtt tgcctatggc ttatcacaaa aaatgagcgt aacagaactg ctgaagctgt
    17521 gtatggcagc cggtatggcc aatgctcaag aagaacgaac aggtcatgtc aatccagcga
    17581 atgtggacat gcattttgaa gagatcaacg taaaaaagat cgagcaataa gctcgatcta
    17641 gtcaggatta attgtttttt gagaccagtt caattttata aaagttccat tttttatagg
    17701 attcaacata ttccagcatt tgctgtgtat cccttcgttt ggtcacacgg acttggagaa
    17761 cagttggttc atcagcagaa atctccagca gctttgctgc atctgaagga gtcgggaact
    17821 tgatttcatt tgtttcggta aagtcttctt cgttcatatg gatattataa tctagcttaa
    17881 agcgttgata gatggaattg taatagctca gttcttgata attaggattc acatattgtt
    17941 ccggcaaata ggtctgctga tagatatacg gagtttcttc ggctttgcgc aagcgtttga
    18001 tgcagtaata aaatgctgta tcaggcaatt cgagcttact taaataaacg ggatcatttc
    18061 ctcgtgtgat tgataagact tgtacctgat cattacttat aggaaacaac tcgatatcgg
    18121 aaaattcgac tatttttcct ttacgggcgc gcgagacgaa agaaccacgg ccttgatgtc
    18181 gaacaatgaa tccatcctta actaaatcat tcaacgcgcg aatgacggtg attgagctga
    18241 cactgaacat ttctgccaac tcggcttccg tataaaattt gtcgccattt tcgaatttac
    18301 cagaaatgat ttgctgtttt agttcatctt ttatgatttg gtattttggg atgaccatag
    18361 gaacctccaa acaatgaata ggaattaaaa gtttcattag aattttttga ttttgtggtt
    18421 atggcttgat tttaacacat tccactaaaa taaggagagt tgactttcag tatcggataa
    18481 tttaatatat taatatatta aaaacgcttt catttaagga gggagctttt gaaaacattt
    18541 gagattaaag aagattttct tttaaacggc cagcccttta aaatcatgtc aggagcgata
    18601 cattattttc ggattgaccc agcggattgg tatcactcac tgtataacct gaaagcttta
    18661 ggcttcaata ccgttgaaac gtatatacca tggaatttgc atgaaccaaa aaaaggtgag
    18721 ttccattttg aaggaatact agatttggaa cgctttttat caattgcaaa ggaactcgag
    18781 ttatatgcga tcgtaagacc atcaccatac atttgtgcag aatgggagtt tggtggattc
    18841 cccgcttggc tactaaacga agacacacgc atccgaacaa atgaaatcgg ttatttaaaa
    18901 catgtggctg attattatga tgtcctcata aagaaactgg ttcctcatca gttgtcaaat
    18961 ggcggaaata ttttgatgat ccaaatcgag aatgaatatg gttcatatgg agaagaaaaa
    19021 gactatttac gttcggttcg agatttgatg ataaacagag gaatcacggt tccgtttttc
    19081 acttcagatg ggccttggcg tgcgacactt agagcaggca gcatgataga agaagatatt
    19141 ttagttacgg gcaattttgg ttcaaaggcc gaagagaatt ttgcatccat gcagagtttc
    19201 ttcgatgaac acggaaaaaa gtggcccctg atgtgcatgg aattttggga tggctggttc
    19261 aatcgctgga aggaacctat tgttcaacga gatgccgagg agttggcgga agcagttaag
    19321 gaagtcttaa ttagaggcag tatcaatcta tatatgtttc atgggggaac gaattttggt
    19381 tttatgaatg gctgctccgc acgaggagtc attgatttgc cgcaaattac ttcttatgat
    19441 tacggggctc cgctaaatga gcagggcaat ccaaccgaaa aatatttcgc aattcaaaaa
    19501 atgattcatg atacgtttcc tgagattcaa caaatggaac cgttgacaaa gaacacaatg
    19561 gaagtaaaag gaattccttt aagaaataaa gtcagcttgt tttcaacttt agacacgatc
    19621 agtcaaccgg tgaaaacgac atatccagag acgatggaaa tgctaggaca aaatactggc
    19681 tacattctgt atcgcacatc gattaaaaag gacgcggaag aagaaagact gagagtcatt
    19741 gatggtcgcg atcgtagtca gctatttcta aatcaaaaat tacaagcgac acagtatcag
    19801 acgcaaatcg gcgaggatat cattgttccg atgactgaag aaaccaatca attagacata
    19861 ttgattgaaa atatggggcg ggttaattac ggacacaaat tatttgctga tacacaaaat
    19921 aaggggattc gaacaggagt catggctgat ctgcatttcc tcactgattg gtcgcagtat
    19981 tgcttgccgc tggattcttg tgaggcagtt gattattcaa gagaatggca gccagagcag
    20041 ccaagttttt atcgctatga agtagtgctt gatgaagtgg aagacagctt tatcgatctg
    20101 tcgaattttg gaaaaggtgt cgtttttgtc aatcaagtaa atatcggacg attttgggaa
    20161 gttggcccaa cactatcgct ttatattcct aagggattac ttaaagaagg caacaatgaa
    20221 atcgtgattt ttgaaacaga aggaaccttt caaccagaga ttcaattggt aaaaaaacca
    20281 ttatataaag aaatgaaaga gggataacaa tgagtattat tggagtaaga attgacggac
    20341 gtttgattca cggacaggta gcaaacttat ggacaacaaa actgaatatt acgcggatca
    20401 tggtggtaga tgatgaagtg gcacaaaatg atattgaaaa aagcggactg aagctggcta
    20461 ctccagcagg cgtgaagcta agcgtgctgc cgattgaaaa agccgctaac aatatcttag
    20521 cagggaaata tgattctcaa cgtctattga tcattgcccg caaacccgat cgtttattga
    20581 agctagttga gttaggtgtt ccaattgaag aaatcaatgt tggaaatatg tcgcaaacag
    20641 atgaaacgcg ttcaattact aaatcaatca atgttgtcga tcaggatgta gaagtattca
    20701 accaattaca tgctaaaggc gttcgattga tcgcacaaat ggtaccaagt gataaagcag
    20761 aagactttat gaatctatta gcgaaatagg aggataagta aatggatatc ttatggtggc
    20821 agatcttatt attaacatta tatgcagggt atcaaatttt agatgaatta caaatttatt
    20881 catcattgag tgcaccagtc tttgccggat tatttgccgg cctagtaatg ggcgatttaa
    20941 aagcaggact tattattggc ggtagtatgc aattgaccgt actaggtgtc ggtacatttg
    21001 gaggcgcatc aaaaattgac gctaactccg gaacgattct agcaacagct ttttcagtag
    21061 cattgggaat gaatccagag caagcaatcg cggcaattgc ggtaccagtt gccagcttga
    21121 tgattcaatt agatattttg gctcgttttg ccaatacgta tttcgctcat cggattgata
    21181 aattagtcga agatatgaat tataaaggca ttgaacgcaa cttcttgatg ggggccattc
    21241 catggtcatt ttctcgcatg attccagtct ttctagcgct ggcatttggt ggaggcttag
    21301 tcgaaaaggt tgttgctgtc ttgaatggtg atttgaaatg gttaggtgac ggtctatctg
    21361 tagccggagc agttttacca gctgtcgggt ttgcgatttt attacgttac ttgcctgtga
    21421 aaaaacactt tccttacttg atcctagggt tcacgttaac agcgttacta ggaacagtct
    21481 ttacgaatat gcaggtttta ggcactggtg ttgcgggtgt tgtgaagaat ttcgaaggca
    21541 ttttcaattc acttcctatg ttagccatcg cattgatcgg atttgcttta gctgcgatca
    21601 gttataagaa tggacagatg attccaaatt ccccagcacc gaaagaagtt gcttccaatg
    21661 attcagatga aggagagatt gaagatgacg aaatctaatt ataagttgac gaaggaagat
    21721 tttaagcaga tcaatcgcag aagcttgttt accttccaat taggctggaa ctatgaacgg
    21781 atgcaaggat caggctacct ttatacaatc ttgccgcaat tacgtaagat ttatggcgat
    21841 gacacgccgg aattaaaaga aattatgaag actcatacac aattttttaa tacgtcaaac
    21901 ttcttcaata caatcgtgac tgggattgac ttggcgattg aagaaaaaga aggaatcggc
    21961 ggaaaagaca ctgtatcagg gatgaaggct gggttaatgg gtccctttgc ggcaattggg
    22021 gattcgatct tcgccgcatt gattccaacg atttttgggg ccttggcagc gaatatggcg
    22081 atcaatggaa atccaaccgg tatcttcatt tggatcatcg cacaaatcgc ggtgatgatc
    22141 ttccgttgga aacaactgga attcgcttat cgtgaaggaa tctctttagt tacaacgatg
    22201 cagcatcgct taactgcttt gacagacgcg gcgacgttac ttggagtctt catggttggg
    22261 gcgttagttg ccaccatgat caatgtaaaa ttctcttggg caccgagcat tggtgatgtg
    22321 acgttgaata tgcagaacaa tcttgatatg atcttaccgc gcttattacc agcaggaatc
    22381 gttgcagcga tttattggat gctaggtaaa aagaacatga cttcaaccaa ggcgattttt
    22441 atcgtattag ttgtctgtgt ggcattatca gtattaggtg tgatttctaa ataagttagg
    22501 ctgattccaa tgaataatga ggagcgaacc aatgggaaaa caattagttt tagtgagtca
    22561 tggactcttt tgtgaggaat tgaaaaagag tacggaaatg attatgggac cgcaagaaag
    22621 catccataca gtcagtttac ttcccgcaga gtcagcggaa gattttcgcg caaaatttga
    22681 agcagttatt gcggatttag atgattttgt cgtgctggct gatttgatgg gcggaacacc
    22741 ttgtaatgta gtctcgcgga tgattttaga agggcaagcg atcgaactat acgcaggaat
    22801 gaatatgccg atggtgattg atttcatcaa tagtgaattg atcggtacag agcttgcatt
    22861 agtcgaatct gcgacaagta atatttgcca cgtgaatgaa cggatcatcg gtgacgatga
    22921 tgacgaggac gagtaaaatc tcatagaaga tgatatagag gcgtcgttta tttgtgaata
    22981 ggagctggtt tgaaagtcta aaagactttc gaaccagctc ctttttctgt tctgctatta
    23041 tggtatgatt gaggagaaaa gaaagaatgg gagattagag tggatttcaa cgagaaacta
    23101 aagcaattac gtcaaaatag gcaatggacg caggaagaat tagcagagag actatttatc
    23161 tcacgaacag cagtttccaa atgggagtca ggtcgcgggt ttcccagtat tgattcctta
    23221 aaagctattt cgcaggtttt tgatatttct attgatgagt tgctatccaa tagtgaattg
    23281 ctgtcaattg cagaaaatga gcagcaacag cagcggaaaa actttcaaca tttgctttta
    23341 ggtatttcag attgcatggt cggcttatta attgttctgc cgatttttgg tcaagcacaa
    23401 gggaaccata ttgcgtttgt ctctttatgg caactttcgc aggaaacaat tatcttcaag
    23461 cttattattt tttcattcgt tattttaaca atgctgttcg gcatttttga actcgctttt
    23521 tctaggcgag aacaacgaat tattggatcg gtttctttga ttttatcgtt gttcggcgta
    23581 ctgcttttca tcatgactag acatccatac ccggcaacgt atgtattaat gcttttggca
    23641 gtgaagggga tttccctatt aaatagccgt tgatacgcat cgtcacatca aggtgacggt
    23701 gcgcttcttt ttgtttctgg cagtctctga tacgttttat ttggatagct tccaaataat
    23761 tgttaggaga ggattagtca aatgaaaata gcaaagaagc aattagaaac agccatagga
    23821 ttattgatcg tctttatttt atacacgatt tctttatcct tgttcgatgt acagaaaata
    23881 ggtccgcagc attcggaggt gggcttttct acaattaatc aatacgtatt tcagaagata
    23941 ggtactagtg aattttggta tcaagtgacg gaaatcttag ggatttttcc attgataatc
    24001 gtggggtatt ttgctttacg aggatttttc caattgtata cccgcaagaa gctcttacta
    24061 gtggacaagg aaattcttgc gctaggattt ctttatgctg gagtcgccgc ttgctatgtt
    24121 ctttttgaaa aagtcatcat caattatcga ccgattttag tggatggaca gctagaggca
    24181 tcctatccgt caagtcatac ttttctggcg attacagtct tactgtcagc tttttatgta
    24241 ttaagaaagg aaacaggaac gggaaaagca atcatcgcct atgtgagcct ggtggtcatg
    24301 attgcgctgg ttatcggacg ttttttgtct ggagcccatt ggggaaccga tatttttggt
    24361 ggaattttat taggtctgac acttgccagc tgctaccttg caggaattga aagtagttct
    24421 aaacaaaaaa aaagaacgtt gaaaactcaa cgttcttaga agagccacct gtcgggcttg
    24481 aaccgacgac ctcttcctta ccatggaaac gctctaccag ctgagctaag gcggcatagt
    24541 tatttaacac aagatataga atagcgaaaa caagcttatt tgtcaactgg ttaaacagaa
    24601 aaaaatgcgg cattagctgc tgtgaattct ttatttataa acgagtcgtc gcttacgagc
    24661 ctgcgacgac ttgtttatat agtttagaga cgatatcatt atatcccttt ggttgagtcc
    24721 agacatttga gagcagaata atgccatttt gaccatcttt tgaaaaatca acaagggctt
    24781 caaaacgtgc cttaactcct cgtgaatggt agttatttgt catgttatag attccgctgg
    24841 cgtatttttc acctggatac gattgccata atgcagcacg ttcttgtgtt gttaaaaatt
    24901 tgtcctgata aagatcttga aaatagctgt acaaatcctc ccccgacata aacacattgc
    24961 ctgttcctaa ttcatctgcg taagaagata cggtcgtagg agcgtaaaca gggccggagg
    25021 aactttctga tttatatgta tattaagata tacgtttata taaacgtatt tatgtatatt
    25081 aaaatacacg taaatatata cgtgattata aaaattaaga aaatattaag tattgttaaa
    25141 tagtgataat tagtaatata cgaattataa gatacatttt tatatttaat gtatgtaaat
    25201 aaataaaatg actgacggat attgaatagt aataaataac aataattcag acggatacag
    25261 tgagtgaagt agcttgctac gaacgaacag gcagaatgaa acggtagttt cattagagca
    25321 agtcgcttgc gacgtagcgt taccactgat gtaactggca agttacatag agagagtttg
    25381 cttgcaaacg aacgttaccc acttgaatag aaaacaaaaa taa
//
LOCUS       DACGMI010000041        25112 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.042, whole genome shotgun sequence.
ACCESSION   DACGMI010000041 DACGMI010000000
VERSION     DACGMI010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.042"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            214..498
                     /locus_tag="IXT46_001900"
     CDS             214..498
                     /locus_tag="IXT46_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAQ4947803.1"
                     /translation="MREIYSFESKIYASEVDKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(779..1198)
                     /locus_tag="IXT46_001901"
     CDS             complement(779..1198)
                     /locus_tag="IXT46_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAQ4947804.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKTL"
     gene            complement(1200..1784)
                     /locus_tag="IXT46_001902"
     CDS             complement(1200..1784)
                     /locus_tag="IXT46_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAQ4947805.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFGIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="IXT46_001903"
     CDS             complement(1831..3306)
                     /locus_tag="IXT46_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAQ4947806.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGMSAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="IXT46_001904"
     CDS             3487..3798
                     /locus_tag="IXT46_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947807.1"
                     /translation="MKKMKESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="IXT46_001905"
     CDS             complement(3913..6249)
                     /locus_tag="IXT46_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4947808.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTDHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="IXT46_001906"
     CDS             6391..7059
                     /locus_tag="IXT46_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4947809.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="IXT46_001907"
     CDS             7062..8105
                     /locus_tag="IXT46_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4947810.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFLQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="IXT46_001908"
     CDS             complement(8342..9223)
                     /locus_tag="IXT46_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4947811.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARNFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="IXT46_001909"
     CDS             9382..10110
                     /locus_tag="IXT46_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAQ4947812.1"
                     /translation="MPTGVLINVGSVLLGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="IXT46_001910"
     CDS             10266..10583
                     /locus_tag="IXT46_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4947813.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="IXT46_001911"
     CDS             10576..11184
                     /locus_tag="IXT46_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAQ4947814.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11200..12030
                     /locus_tag="IXT46_001912"
     CDS             11200..12030
                     /locus_tag="IXT46_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAQ4947815.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            12168..12680
                     /locus_tag="IXT46_001913"
     CDS             12168..12680
                     /locus_tag="IXT46_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAQ4947816.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQARGWYITEDKELELEGVMARIRK
                     KIKKVTLDIY"
     gene            12706..13578
                     /locus_tag="IXT46_001914"
     CDS             12706..13578
                     /locus_tag="IXT46_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAQ4947817.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13754..14116
                     /locus_tag="IXT46_001915"
     CDS             13754..14116
                     /locus_tag="IXT46_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4947818.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14125..14877
                     /locus_tag="IXT46_001916"
     CDS             14125..14877
                     /locus_tag="IXT46_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947819.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14891..16693
                     /locus_tag="IXT46_001917"
     CDS             14891..16693
                     /locus_tag="IXT46_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4947820.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIILGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16970..18010
                     /locus_tag="IXT46_001918"
     CDS             16970..18010
                     /locus_tag="IXT46_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAQ4947821.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18062..20206)
                     /locus_tag="IXT46_001919"
     CDS             complement(18062..20206)
                     /locus_tag="IXT46_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4947822.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20563..21936)
                     /locus_tag="IXT46_001920"
     CDS             complement(20563..21936)
                     /locus_tag="IXT46_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4947823.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21936..22331)
                     /gene="rbsD"
                     /locus_tag="IXT46_001921"
     CDS             complement(21936..22331)
                     /gene="rbsD"
                     /locus_tag="IXT46_001921"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAQ4947824.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22359..23276)
                     /gene="rbsK"
                     /locus_tag="IXT46_001922"
     CDS             complement(22359..23276)
                     /gene="rbsK"
                     /locus_tag="IXT46_001922"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAQ4947825.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23384..24397)
                     /locus_tag="IXT46_001923"
     CDS             complement(23384..24397)
                     /locus_tag="IXT46_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4947826.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24478..25077)
                     /locus_tag="IXT46_001924"
     CDS             complement(24478..25077)
                     /locus_tag="IXT46_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4947827.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTIKKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
BASE COUNT         7625 a         4546 c         5122 g         7819 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cgacaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatgtttt ttcaccatct ttataataaa ctggttcttt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattc caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcactcatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgaa ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg atccgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atctgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gtttttttgc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaattt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 cttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tctgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aaggggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa attaaaaaag
    12661 taacattaga tatttattga aggataaagg agcgcaggaa gtagcatgag agaaaaaaga
    12721 gcattttata tcaatggtta tgcagggatt gtcggattgg tcgtattagc tttagttgga
    12781 ttgtttttct tctatttagg tatgtggcaa gcgaaagttt gggcactttt tttaagtatt
    12841 tttctttggt tgatcacgtt attgttgtta agttcggcaa ctgtagtcag tcctaatcaa
    12901 gcaaaagtaa ttttgttttt tggacaatat ttaggtacga ttcgagaaaa tggctttttc
    12961 cttacgatac ctttggcaca aaaaatgact gtttcgttga aagttcggaa tttcaatagt
    13021 tctgttttaa aagtcaatga tttggatgga aaccccatcg aaatctcagc agtagtagtc
    13081 tttaaagtcg ttgatacagc aaaggcatta ttcgatgtag cgtattatca agattttgta
    13141 gaaatccaaa gtgagacagc cattcggcat atcgctagcc aatacccgta tgatacattc
    13201 aatgagaatg atttgacgct tcgaggaaac acgacggcag tgtctgacga gttgcaaaaa
    13261 gagctgcaag agcgtttagc agtagcaggt gtcgaagtaa tcgaaacacg cttgaaccat
    13321 ttagcctatg caacagaaat cgctagtgcc atgctccaac gtcaacaagc aaaagccatt
    13381 ttgtctgctc gacaaaccat tgttgaagga gctgtcacaa tcactcaaat ggccttagag
    13441 caaatcgaag atggacaaga aatcaatttc accgatgatc ggaaagtcca attgatcaat
    13501 aatttacttg tctcaatcat tacagacaaa ggaacgcaac ctgttatcaa tacaggcgac
    13561 atgaaagacc gtaagtgaca tactttttgt aagataggaa gaaggagttt aggacggatt
    13621 attgtcttga actctttttt tagttgtttt aaagaaaatg acaaaattga aagaagaatg
    13681 atagttgatt cgaaggcaga attgttcgct tttttctata atcagtatat aaagtaagag
    13741 agaaggggaa aaagtgaaaa aacttctgat cggtctactt gttttcatcg ttgtggtact
    13801 tgcaggggtg aaaatcgcag attacgtagt tatgggtgga gaagaatact atgtacaaat
    13861 tacgacagat ggtacaaaaa cagtttcaaa atcagactct ggacaagaaa cagtcaacta
    13921 tagatatatc ctgcctggct atacgaaaga gggtaaggaa aaagaactgg acttcaaggg
    13981 acaattgact cgaccgcttc gtaaaggagc atatttaaaa atcacctgga acaaaaataa
    14041 aggtgtcact tcgtatgaag aagtcgaaaa aaaagacgtg ccgaaaacag cactggaaaa
    14101 actaattaaa gggtagggaa agaaatgaac aaaatagtcg aagtacagaa tgtaacaaaa
    14161 gtatacggaa aaaacaatga gaaaaagacg caagcattaa gcggcatcag cttcgatgta
    14221 gaaaaaggcg aatttattgg gatcatgggc gcttctggtt ctggtaagtc gacacttttg
    14281 aatattttat ccacattaga taaaccaaca gatgggcata tccgaatcaa tcaaaaagat
    14341 gtgaccacat taaaaggaaa tcaactagca gattttcgtg cgaatgagat tggctttatt
    14401 ttccaagatt tcaatttatt agaaagcttg acagcacaag aaaatatcgc tgttcctctt
    14461 tctttacaag gcgtcagacc aaaagaaatc aagcaacgtg tccaaaaaat tgcagaacgt
    14521 ttatccatct ctcatatttt ggaaagctat ccttctgaga tttccggtgg acaaaaacaa
    14581 cgggtcgccg ccgcacgtgc attgatcaca caaccaacga ttctattagg ggatgagcct
    14641 acaggtgcgc tggattccaa aagtgcccgg gatcttttag atacgatgga cgaattgaat
    14701 acaaaagatc atgtatcgat tcttcttgtg acgcatgatc cgttttctgc aagttattgc
    14761 caacgtattt tattcatcaa ggatggcggt atccatcaag aagtgaaacg tggagatcaa
    14821 agccgtgatt ccttctatcg agaaatacta tctattcttg gaaacttgga acagtagggg
    14881 gagattgact atgctttgga aattatcact tactgggatc aagagccgtt taagagacta
    14941 cttggtgtta ttctcaggat tagttatggc atctgctatt ttttacatgt ttgaatcaat
    15001 ggcaagcaac gaagcttttt tgaaaagtaa tacgatcgtt gcggctacag ttatcatttt
    15061 ccgattcggt tctgttttac tagggatcat cacattcgtt tatattttat atgcaaattc
    15121 ctttttgatg acgatgcggc aaaaagacta tgcaatgttt atgatgctgg gagcaaaagg
    15181 cagaaaaatc gcacagatga ttttttctga aacattctta gtagggatcg cagctacttt
    15241 agtgggttca gctgtcggtg taggattgac aagtatcgtc caccgattat tagtggatca
    15301 gttagatctc aatatttcgc attttacacc ttttagtatt cacgggttgt tgatcactgt
    15361 tttgtttttt gctgttttgt ttttattagc tgctgttgtc aatgcttttt cgattgtcaa
    15421 aaaaccgatt ttagcattga ttcgtgcgga tcagacacca acaagaatca agcagcataa
    15481 attcttgttt ttccttgaag tagtactggg aattgctttt ctaggctgcg gttactatat
    15541 gatgaaacac gtggggacct atcaagtctt tggtataggg gtagccttag ttacgatcat
    15601 attaggaact tatttcattt tccattctgt gatcattttc tttttatcat tactaaagaa
    15661 atcagaacag atttcattga aaaaattgaa caatttcaca ttgtcacagt taaactttcg
    15721 tattcgtgaa tatacacaaa tgctctcaat ggtcgctatg ctgtttgcct tggcactggg
    15781 cgctttgacg gtaggattag gttttaaaaa tgaaattgca gacttgacag aaaacaattc
    15841 tggatatgat ctagtgatga ataatcctcg ggcagaagat cagcaaaaaa tcaaagaact
    15901 ttcaccaaca ctttctgctt cttatactca aaaagaagat gcgggaacga tttactataa
    15961 tgcaagtgaa tttgcggctc aaccattgat catgataaaa catgaagatg gaacaccgcc
    16021 gaagatcacg aaagaaaaag ttcctgctaa aaaaatgaat gaactgactg tacaagagga
    16081 acttcgaagc tatgaattgc cggaacagca agaaaaagaa atcaaggtag tcagtcaatc
    16141 agaatttgat caactgaact tgccacaatc cactttacag ctagttcagg taaaagactt
    16201 ccaagcaaac ctgaaaccaa tcgaaacact tgttgctcaa aataaaatga acaatccatc
    16261 tttgcaaaaa gtagagtaca gcaaccagaa atatgaaatg tatgaagtgt ataatggtct
    16321 attctctggt tttgaattta tgggattctt cctaggttta gctttcttga ccatgcttgc
    16381 tagctgtttg atgttcaaga tcttgtcagg aagcaagagt gacattgctc gttatgaaat
    16441 gcttgaaaag ataggaacac gacgcgggtt gcttaaacaa tcgatccgta gagaagtagg
    16501 cgtgttattc ttagcaccag gaatcttagg tgtagtccat gtcttattcg gattacaaat
    16561 gtttggtcta ttcatgcaaa atccatacaa agatatttgg gttccgttta cgatcttctt
    16621 cgtattgtat ttcatctact atgtactgac gacatggtta tatactggaa tcgtattgaa
    16681 aaagagattg tgaaaaagct gtcctgcatc aagtaataag aacagccaag caaaaatagc
    16741 tcctcatatt tttcgtttgg ttgggcttat taccgcagat gcaagctttt gaacaccgtt
    16801 tgttcggaaa aagaggttgt gacaatattt ttgtcacaac ctttttttca cggtctttta
    16861 ttagaatata gtaaattttt tctcgttact cacggaataa gctgttaaga aaacggtttc
    16921 catgtatact ggaatcagtg caaatgaaag aaaagagggt gcaaggaaca tggaaatcaa
    16981 tgaacaaaat tttggcgaaa actatcactt gattacgatc acgaatcaaa atgggacatc
    17041 tttgtctgtc agtgatcttg gggcacgggt tgttcatttt caaacaataa tcgataatga
    17101 aaaacgagag ttgatcttag gttttgatga agcaaaagaa tatctagaaa aagaccctta
    17161 tatcggtgct tcaatcggac gtatggctgg acggattacg aatggcacat tcaaattaga
    17221 tgatgaaacg ttcgaagtaa aaacagaccc ggacactggt cattgtttac atggtggtgc
    17281 acctagcttt gaagccaagc agtggcatta tacagtcatc aatggtgaaa acgaagcatc
    17341 ggtcattttc tatcagacta gcccagatat ggaaaacgga tttcctggaa ctttagatgt
    17401 agaagtacgg tatacgctga cgaacgatga tacatggcga gtgacggtcc aagggatcag
    17461 tgaccgcaaa acagtattca atcctacaaa tcatgtctat ttcaatttaa ccggtgatcc
    17521 agcacagtca atcgacgaac atatactttg gttgaatagc cgattatttg ctacgctcaa
    17581 taaagataca acgcctacag gagaagtagt ttcagtaagt ggcacagcat ttgacttcca
    17641 acgtcctaaa aaattaggtg aggtctttgc cagtgatttt cgccaatcaa tgatagtggg
    17701 cggcatcgat catccatttt tgttgaaaaa acaatctggt ttactaaatg ctgcggaatt
    17761 gacaagccca gatgaaaaag tatcgatcca agtaaaaaca gatgcttcag gaatcgtgat
    17821 ttttacagca aattttggag aagatggacc ggaaatgcgc gggaataaat tagtaaatca
    17881 tggcggtatc acatttgaga ctcaagaact gccaggagcg gagcgacttg aaagttttgg
    17941 agatgtcact ctggaaccta accaagtacg cgagtttgta acggaataca aaataaatat
    18001 aaagaaatag aataaattaa aaagggagtg tgacagtgtc acatcccctt tttaatttat
    18061 tctatttctt taaaggcaga tcaagccaga atgatttgtc taaacttaac aaggttagta
    18121 caggaacagt tgcagcttta actgtacgag tagttgtttc tggtatctgt cttgccgtaa
    18181 aattgttcca caaatcccag attgaagcga cacggaagat ggaagaagcg ttgttgacgc
    18241 gttttatcgt tgaaaattct aatcctgtga ttggcacgcc atctgttgtc catttgattg
    18301 gcacatcgaa tcgcttagac atattgagga tttcagcgtt tgcttcttca gttgttgctg
    18361 cttctttttt cggttcatca tattttgtca ggtcgtacgc ttcgatgatc gcgttcaatt
    18421 tttgtgaata ttggcgatct gtagcataac gtccttccaa atatttggtt gcttctttgt
    18481 agtcttttgt ttccgacttc caagttggtt tgtagaaatc aggattgcca gtcagtccat
    18541 ttttgatcaa gtcggcatag tcttccaaac tttccttgta agaaggatat ttacggaatt
    18601 gtgcgcggat ttggtagctt tgtccggaac tatcttgttc aagtgtattg aaggtcacgc
    18661 tgcttccttt atatgatcct ttgataccaa aaaggttatg atttggttcg cttgataata
    18721 agctgtttcc agatccactt tcaaggatag cttgagccat catgactgat gcgtagattc
    18781 cttctttttg cccgatttcc tgtgcatcat ctgcaatctt tttcaagaac tgatcagttg
    18841 tttggttttg actgaaatgg aacgagccat ctaatccatc taaaatagat gagccgcctg
    18901 tcagcgaacc tgaagcagca ggtaaacctg ctaagtttac tcggacagca aaatcaggcg
    18961 tgaaatctga aatagaagtt actcgaactt tatctcctgg ttgaggcgca tggataaatt
    19021 gtccgttccc aatatagata cctacatggt gagtaacacc ggaagaaggt ccccagaaga
    19081 cgagatcgcc aggttgggcc tgacttactg gaatctgcgt acctgcatat tgctgttcgc
    19141 ctgtccagcc accgatataa tgaccggttg ctttcatata tacgtaataa gtcaaaccag
    19201 aacagtcaaa agtatttgga ccttttgctc cccatacata tggttttcca agatgcttga
    19261 atgcttctcg aacgattgct tgttggacat tcgttgtatt tgtaggcaat acagcatcaa
    19321 ttggtgattt tacaacaaaa tcagaagaag cagaagatgg attctctata ccgctttgat
    19381 ttgctgtatt tggacgagat gaagcattgt tcgttccgcc attcgatgaa ccattgtttg
    19441 gatggtttgg ttctctctga gtatttccat tgttattcga tccagatggg tttgtttgat
    19501 tcgaagaatt cccgctgttc gaattattgt tattattgtt tgaattattt gaaccattat
    19561 tattgttgtt attacccaca tctggtttgt ttggcgtttc cggatctggt gtactaggga
    19621 cttcttcact aggatcagtt ggtttctctg ttgaagtatc cggtccagct ttaaattctg
    19681 cagtaataga taaattgttc gtacctactg taaaggtctt tgcatcataa tttacttctt
    19741 tggcaccatt aacagcgact gaagcaattt gttcaccttc agctggcgta atagtgtaag
    19801 ttaccttcgt ttccgctaat aaaccttcta ccgttccact ttccgtaata tccaaaggtt
    19861 gctgttcagg ggaatccgct gtcgaagcag tcagttggat cttaccaatc aaagaaggag
    19921 caattgtaag ggaatatgtc tcggctggct tttcattttc tgatggatca gccggatcaa
    19981 tttcagttgg ctcggtcgat cctgttgttg agttagttgt tccagttggg tcttctgtaa
    20041 aagaatccgt tgtttcacta gtagctgagc tggatgtagt cgtatctgtt gtgactgttt
    20101 gatcagctat ttgattatct acggcaaata cggtattggt cgacaaaaca gacggagcaa
    20161 tcagccaagt agcagctagc aaacgtatcg tttttttatt tttcataata aactagtcct
    20221 tttcctttca ttgattttct gtcttattca gcattcatta gacatttttt ggaacagata
    20281 atcgtgtcga aaagcttttt cttttcataa atctgtctgt gtattctaaa taaaacaatt
    20341 tgtaaataag caacgagcat tcattcgttt ttctttgacg ttcattttat tgcatagacc
    20401 acctttgttt ggggataaac aagtggggat aaaaatggtt atgcatatgt aaattatacc
    20461 aaagtttgga aagtatcaca aaaatttata aaaataatga tcctaaaaag aaaaagactg
    20521 aaatatgtga taaacatctc atacttcagt ctttttcatt aactattcat aagacattag
    20581 gtcttcatca aacccgctaa cgagagtagt gatcattgct acgactagac taacagccag
    20641 tcctgctaag taccagaaaa aagtaccgga aatgaatgca ggcaatgtgg tcagactacc
    20701 aaatacaaaa gcgatcgctt tcacttgggc aaatcccatt acagctccac cagcagctgc
    20761 accaatgcaa gcagcaacaa atggtttttt caatgggatc gcaattccgt aaacagttgg
    20821 ttcggtcact cccgcaagta aaatcgaagc aaaagcagaa ccggagatcg aacgggtttt
    20881 tgaacgttta cttcgcagaa atacacctaa agctgcacca gccattccaa aattggctgc
    20941 tcctgtcaac ggaacgattc ggtcgaaccc ataagcagag atattactga tcatgacagg
    21001 gtttacagcc cattggatac caaatattac caaaatattc caaccaccag cgatgattgc
    21061 gccactgatc ggtccgttaa tatccatcat ccaagtaatt gcggcagcta aaccttcgcc
    21121 aaggtaaaca cccgcaggcc cgaataccat taacgtcaaa ggaaccgtga taactaatga
    21181 aagtaaaggt acaaatacta attgcatatt ttcgcgaata tattttttga ggaatttttc
    21241 aacaaaagaa taaaagaaaa tacctaaaat cgccggcatg acagtagacg tatactgcat
    21301 cagtactaca ggaatcccca gaaaatcagt agctgctttg ccactgtctg aaagtaaaga
    21361 ggtcagattc ggttcaatca gtgctgcagc aatgacagcc gcaatatatc cattcacttt
    21421 aaacgttttg gcagcagaaa aagcaagaaa gattggcaga aaataaaaga cggcattcga
    21481 cgcagcagac aaaatatgat aagttccgct tgtttcacta agccagccaa tcgtagtcgc
    21541 taaaacaacc agacctttta atataccaga accggcaaac agcggaatga tcggcgtaaa
    21601 gatttccgat atcaaaccaa atagtttttc gatcggattt agcttttctt tcggagctga
    21661 atgatcgatt tgacgcgtca attccttgta agcaggagcc aatccctgat ccatgattat
    21721 ttctgcatat ctatcgagta aaatgaaata cttaatggaa gggatttgct gttttaattt
    21781 ttctgcattg gctactggct gttttttcaa tttgatacga agccgagtcg cacatggaag
    21841 gacagaatca atattgtctt ttcctcccaa ctgttcaatc agcatatgaa tctgctcgga
    21901 cagtaccatc tgttcaggat tcattgtcgt ttccattaga agaccactcc actcactaat
    21961 ataatattgg cgtaaggtgt catttcgcct gtacgaataa atgcatgaca gttattcaac
    22021 tcttttttca tttcttcatg tgggataaag ctaatcggtg tatctggtaa caataatttg
    22081 attttttcca atatttccgg gttcattgtc tttatttctt ccgccaattc aatcgattgt
    22141 acctcaagtt cttctaaaac gttttctaaa acagataaaa aacttggaag accgtttgag
    22201 acagccaaat ctattttttc agtaccaaag gggacaggca tgcctgcatc cccgatactt
    22261 aatttatcaa agtgccccat ttgtgcgatt actcgtgaaa tatctgaatt gattactttt
    22321 ccttttttca tgtttgtttc ttcctctcat tgttaatttt agactgctga ttgttctaaa
    22381 gcttcgcggt aagggataga aggttgcgca ccataagact gcacagcaac agaagaggct
    22441 agatttccat aaaggatcgc ttctttcaag ttactaaggt ctggctgaag tgtgctgctt
    22501 aatgcgccaa taaatgtatc acctgcggct gttgtgtcaa cggcatccac tttaaaagca
    22561 gggacgatac cgtgttcttt ttctgtatga tagaaagcgc cggcactgcc tagtgtaatg
    22621 attactgttc caatacctaa ttcatggagt ttttcggctg ctgcgaccaa actgttatga
    22681 tctgtcactc tgattcctgt aatgatttct gtttctgttt catttggtat aatgatatct
    22741 gtcttttcaa gtagttcagt aggaatcgtt tcacgagctg gtgcaggatt caggatcgtt
    22801 gtttttcctg cgtcttttgc aatagaaaaa gctaggatcg tcgcatctaa gctactttca
    22861 aactgagcaa taataaagtc actgtttgta atcagttgct tgttttttag gacttcttgt
    22921 tcatggaaag cattatttgc ccctgcatgg atcaagatac tattttctcc tgctgcgtct
    22981 accataatca ttgcttgtcc ggttgtggcg ccttggattt cagctatccc agatgtatcg
    23041 atgttttctt ttgtcagtag atctaataac tgttgtcctt cgctgtcagc cccaacgcct
    23101 ccaataaaag atgtccgtgc gcctgaacgt ttggctgcca ctgcttggtt ggcaccttta
    23161 cctccgccag cgtgaaaaat ctcatgcgca tgcatcgttt cgcctggctt gggcatgttg
    23221 gttaaacgaa gggtagtgtc catattaata cttccaatta ctgtaaccgt gttcatttta
    23281 caaacctcca actatctcat ttattttgat gggaaaatta ttttttaaaa cgttttagta
    23341 aaacgtttta atagttcgat aaaaatatag cacaccttga aagctatttc aagggtgcag
    23401 ttgaaaatct tttttctaat cgtacaggta atcttttttc ttcccattct ttttctggga
    23461 attggatccg atctaacaat aacttggcag atgtttgtcc caattcgaag attggttgtg
    23521 cgatcgttgt cagtttcggc ttgatatact cgcacatatc tatattatca tagccaataa
    23581 tgctgtagtc ttcagggatg ctttttccag cttcctctaa tccgcgatat aatccaaaag
    23641 ctaattcatc atttaaagca aacacaccag ttgcagcaga atcaagaagt tctgctgtga
    23701 tctggtagcc accttgtttt gagaactgtg taggtaagag gatcagttgg tcgtgaggga
    23761 tttggtaaac atcaagagca gatttaaacc cctcaatccg agcgtggaca ttttccggtg
    23821 gattttcagg atagacaagg gcgatcgttt gatgtcctag actaagcaag tgcatgcccg
    23881 ctaggtaacc accgcgaaaa tcgtctgttc gtacggcatc actaaatcct tcagattttt
    23941 tctgatccaa aacaatgaag ggccggcctt gttttttcaa attttcgttg attgcatctg
    24001 tagagacagc agaagtcgcg ataatgaatc catccacacc tcgacgtgtg agctcggcta
    24061 gatattcgat ttctttttga tgatcagaat cagcattaca taatatcgtg acgaaattct
    24121 gcttatacaa gatatcctca attcctcgca tcagtgtact gaagaatgga ttcgtgatat
    24181 caggaacgag tacaccaatt gttttcgttt ccttggtaat catttgtcta gcaaaatagt
    24241 caggctgata gcctaattct tctttggcag ctaaaacttt ctgaacagtt ttcggactga
    24301 atttctccgt atttccattt aatatcaagg agacagttgt gattgaaacg ccggaaagtt
    24361 tagcgacttc tttgattgtg atcttttttt tcaccatgtt catactccta tctaaatcct
    24421 gtggttattt tcccatgaaa tcaaaaagaa gtaaatgaaa atcacgtgtg ccagtactta
    24481 tttgctttgt tggatagctt cgattatttg tttcgttgag cgtactcgtg cagttttcgg
    24541 aaatatcttt tttatgaaca attgatggga ttctttgtca cgatcactgc aagcatcttc
    24601 agcaagcacg atatggtacc cgtgttgaaa ggcatctaat gcagtagcat atacaccgtt
    24661 tgttgtcgct acaccgctta aaatgatagt ttcgattcca cgccggcgaa gttgaagatc
    24721 aagagaagta ccaaaaaaag cacttggatt gtattttttg atagtcaaca tattatctgt
    24781 atctttcaaa gaatccttca aaagtaaatc agtgaattct ggaggtacag aagcagtcat
    24841 tccacccata tcagtttgtt gactcaaata agggaaagtg gagatgtcta cgttcactaa
    24901 aactttcaag gcagcggtac gtttcaatgt tcttactaac aaatcattgt ttgtcagaat
    24961 agatgctgca gtgtgtggag agagtgtacc gttatttacg atctcttttt gcatgtcgat
    25021 cgcgacaaaa gcagtttttg ataaatcaaa aatcatattt tcctttaaat cattcatgat
    25081 gttccttctt tcaaataaca atgtttttta tg
//
LOCUS       DACGMI010000042        24579 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.043, whole genome shotgun sequence.
ACCESSION   DACGMI010000042 DACGMI010000000
VERSION     DACGMI010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.043"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(153..551)
                     /locus_tag="IXT46_001925"
     CDS             complement(153..551)
                     /locus_tag="IXT46_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HAQ4947828.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(548..1321)
                     /locus_tag="IXT46_001926"
     CDS             complement(548..1321)
                     /locus_tag="IXT46_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAQ4947829.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1318..2001)
                     /locus_tag="IXT46_001927"
     CDS             complement(1318..2001)
                     /locus_tag="IXT46_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAQ4947830.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2168..3055)
                     /locus_tag="IXT46_001928"
     CDS             complement(2168..3055)
                     /locus_tag="IXT46_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4947831.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3052..3921)
                     /locus_tag="IXT46_001929"
     CDS             complement(3052..3921)
                     /locus_tag="IXT46_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4947832.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4058..5344)
                     /locus_tag="IXT46_001930"
     CDS             complement(4058..5344)
                     /locus_tag="IXT46_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4947833.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5617..6195
                     /locus_tag="IXT46_001931"
     CDS             5617..6195
                     /locus_tag="IXT46_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAQ4947834.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPMKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6195..7124
                     /locus_tag="IXT46_001932"
     CDS             6195..7124
                     /locus_tag="IXT46_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4947835.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7121..8857
                     /locus_tag="IXT46_001933"
     CDS             7121..8857
                     /locus_tag="IXT46_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4947836.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="IXT46_001934"
     CDS             complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="IXT46_001934"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAQ4947837.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9753..10262)
                     /locus_tag="IXT46_001935"
     CDS             complement(9753..10262)
                     /locus_tag="IXT46_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAQ4947838.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="IXT46_001936"
     CDS             complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="IXT46_001936"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAQ4947839.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11563..12654)
                     /locus_tag="IXT46_001937"
     CDS             complement(11563..12654)
                     /locus_tag="IXT46_001937"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAQ4947840.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="IXT46_001938"
     CDS             complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="IXT46_001938"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAQ4947841.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="IXT46_001939"
     CDS             complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="IXT46_001939"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAQ4947842.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="IXT46_001940"
     CDS             complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="IXT46_001940"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAQ4947843.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16617..17591)
                     /locus_tag="IXT46_001941"
     CDS             complement(16617..17591)
                     /locus_tag="IXT46_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAQ4947844.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17572..19455)
                     /locus_tag="IXT46_001942"
     CDS             complement(17572..19455)
                     /locus_tag="IXT46_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAQ4947845.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19473..21698)
                     /locus_tag="IXT46_001943"
     CDS             complement(19473..21698)
                     /locus_tag="IXT46_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAQ4947846.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21813..22847
                     /locus_tag="IXT46_001944"
     CDS             21813..22847
                     /locus_tag="IXT46_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4947847.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22914..23927)
                     /locus_tag="IXT46_001945"
     CDS             complement(22914..23927)
                     /locus_tag="IXT46_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4947848.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYWGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24005..24193)
                     /locus_tag="IXT46_001946"
     CDS             complement(24005..24193)
                     /locus_tag="IXT46_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAQ4947849.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         7065 a         5341 c         4397 g         7776 t
ORIGIN      
        1 agcatatttt gaaaagaaag tctgatgctt agagtagaat ttcataaaaa tttactattt
       61 cataagtatt cacgagaaaa atgcaaacaa aaaagcggaa ataacgctca tccgccttct
      121 tgtttgtgtt tatttcctct tcaaacgctt gtctatgatt cagacttttc tctatcgtta
      181 ttttcatcta aaagttcttg cattccgata atttctcgat attgatgaat cttagtgata
      241 ccaatgactt tgtctacatc aatactaaaa caaataccat tacctggaat atcgatgttg
      301 atgccttgac caatcgcatc cattacttta ttcgtcaaac tatcgggtac taatgtcaac
      361 acaatatctt tttctggcga aatgtccaaa cctaaaaatt tccctgaatc atgtacacca
      421 gaacctcttc catgtaagat cgttccgcct gctgcacctg cttcttttga aaagtcgata
      481 acatcttcgc ccattcctcc gtcaacgatc gtcacaatca tgtgaagatt caatgctaca
      541 agatctttca tttgctttcc cccaattttt gcaatctttc tttttcgatt ctgtcttttt
      601 catcttttcg tttataaata tatcctagta ctaaagtgga taatattggt gtcaatgcaa
      661 tcattgcaac cacaccaaac ccgtcaatga tcggatctct tccttcaatt tgtgcagcga
      721 ttgccacgct cattgataaa ataaatgtcg aacacatcgg gcccgttgct actccaccgt
      781 tatcaaaagc cattgctaaa aagatcttgt ccacttttcg tcctaaaata aatgctagcc
      841 cgtatcctgg gatcaagaaa taataaagag agaatccgac gagcaaacgc cacatagaca
      901 atcctactgc tgcgccgatc ccaattgaaa ttaccatcag catgattttc gatcggattc
      961 tcccctcgct caattcttca acctgtttga tcattacatg aatcgccggc tcagcaaacc
     1021 ctactaagaa ccccattaaa aagccaaggg gaaccagtat ataattgtaa ggcaatcccg
     1081 caatagcact gcctaaatgc tgtcctaccg gtacataagc catattgact ccgtgcagga
     1141 aaaggatcaa cccaatagtc gttatcaaga aacctttcat aatgtcaaag aaacgctttt
     1201 tgcgcatacg aaaactaatg atattcatta aaacaaatag gattacgata ggtgccactg
     1261 ccaaaatgac ttccatggta acgatttcga ttccatctat cacttgctgc cagaaactca
     1321 ttggaagatc acccccaaaa tcatcacggc aagaatcggc cctaacgaag caataccgac
     1381 cattccaaaa ctgtcatttt catttttctt ttgtttgatc atactagtca tccctccggc
     1441 aagggccaag ataaatggaa cagttactgg accagtagtc actccccccg aatcaaaagc
     1501 aatcggcata aattcggaac tggtgaaaaa tgaggcgatc aaaacgccta tgtagcctat
     1561 agccatcaat tgataatagg atagcttgaa tacgacccga agcagcgcaa aggctagaaa
     1621 tactccagtg ccgacgctga cgatcccaat cagcaacact ctgccaatct ctccgtcaga
     1681 tatatcatat acttgttgtc ccaaaacttg cacggaaggt tcagcaatcg tgatcacgat
     1741 cccgatagca aatcccaaac tgaccaaaac ggtcaaactt ttctttttga tcatatattt
     1801 ccctactaga tctccgactt ccatcataga ataatctgct ccaaacaaaa agagcgtcat
     1861 tccgatcatc atgattgccg caccaaccag aaatgaagcg aggtcttctc cttctaacgg
     1921 tgcaaaaaca aacgttaaaa tgacaatcag gacagtcatc ggcaatatag cagcaatcac
     1981 ttctttaaaa ttttttagca tgtatcctcc tcctttactc tttaagttta ccttaaaatg
     2041 aaagagtttt cgagcacaaa cttaaaacgt tatcatttaa tttttctcaa cataaaataa
     2101 cacacgtccc aaaagtatct ttttacttgg aaaaatgact ttgaaggaac gcgcttattg
     2161 tgttttttta ttttacagag ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa
     2221 atacgatggc agttggtaaa gtagcgatga ctaatccagc catgatcatt ccatagtctg
     2281 gtgtatagga agcacccata gcagataaaa caagcggaac cgtccgttta tcaggagatt
     2341 gcaaagctac taagggccat aaataattgt tccagctact catgaatgtg atgattgcag
     2401 ccgcggcata ggtattttta gccgtcggca tatacactct aaaaaaaata cttagttctt
     2461 ttagaccgtc taatcgagcg gcttctacta gatcttttgg aaaagattta acattttgtc
     2521 gaaagaagaa gatcaaaaaa gcagtgctaa cagatggcag gatgacaacc aagaaactgt
     2581 tgattcccaa aaccgttccg ttcaattgtg aaaacattcg atataaaggg atcatcaatg
     2641 ccgcaaaagg aaccatcatc gatagcagta gaatattgaa aattaggtct tttcgtttac
     2701 tttgataaat ctcaaatcca tatcctgcca ttgacgaaat cagcaatgca aacacagtgg
     2761 tcaccaaagc gatcatcgct gaattccaaa gggaacgagt aaaattcagc tcattggaaa
     2821 acaaattttg aaaattgatg atcaagttac tgccaatctt tatttttccc gatgtgatat
     2881 ccacgggtgt attcgtcatt cccaaaacca tccagacaaa agggaaaatg gaaataaatg
     2941 ataggatgct taatgctgta tactttaata ctgacccaat tgtcgaacga agttctaatg
     3001 cttgtttttt gacgttgggg cgttcgattg tttctttttc taccatattt ttcatcgact
     3061 ttctcctcct actttcgttt ggattatcga caatatcaca ataaaggaaa caataacaaa
     3121 ggaaactgct gccgcatatc caaaattagg cgtgaattta taactcaaat tatagatgta
     3181 ttgagatagg gtggtcgttg catttgctgg tcccccgcca gtaatatttt gtacttcatc
     3241 aaaaagctgc aatgtcccga tcgtcgaagt aatggaagta aacaaaatga ttggttttaa
     3301 atttgggatc gtcactttga taaactgctg ccatttagaa gcaccgtcaa tagatgctgc
     3361 ttcataaatc tccgaatcaa tattttgcat gcctgaaagg aaaaaaatca tattgtatcc
     3421 agtccaacgc caagtgatcg aaagaatgat cagaactctc gcccaaattg gatgagtcaa
     3481 ccagccaatc ggtgtgtcaa tcataccaat gcccaacaac aagttgttta caaggccaga
     3541 ttgagaaaat agacttttca tgatcagaga ataactgacc atcgaagtga tacatggaag
     3601 aaagatagcg gttcgaaaca accctttata tttcaacttt ttatcattta aaaggttgga
     3661 aataaaaagt gctagaaaca acatgatcgg tacttgtaca agtaaataca ggaatgtatt
     3721 aaaaaaagct tttttaaaag ttgcatctgt caacatccgc tgataattac ctaacccgtt
     3781 aaatgtcata ttgacagggg gaccactttg aaaagacgtg atcaaagcca aaaccatcgg
     3841 aataaaaacc atgattgata tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt
     3901 gaataaatct ttctgcttca ttcttttccc tccaattcta tcattgatta tctacatgaa
     3961 aagacaagaa agacaatatc tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct
     4021 gatgaaaaag cgaagaaatt cactttttta ccaccgatca attagccaat tgtgcttcta
     4081 cttgtttttg tgtatctgct agtaccttgt ctgtctcttc tccattgatg attcgatgaa
     4141 gagcttcagc tacgactgct tcaattgcat aggtctcatg tccgtaattc acttctggta
     4201 tttcagatgt ccatgttgaa aaatcgtcaa agatcttttg accactgtaa aattcagaag
     4261 cttcttgata agcttcttgt tcattcgcgc taagcatcgt agatactagt ccgatttctt
     4321 tcgcaagagt gcccatcagt tcttcattcg aagcaaacgt tgcttctagg aaatctttcg
     4381 ctgaatcttc tccagctact cctttgatca cataccagcc agcgccgcca aggttagaag
     4441 cttgcgcttt ttgcagattt tctggaagtg caggtattgg tgcaatcttc cattttccag
     4501 attggttttc tgctccttgg atcgttgaag aataccaagc gccagttggg ctagaagcta
     4561 ctgctcctga ttgtatcgca gttactccag cattccagtc agaggtttgt tcgactagat
     4621 cttctttcaa aagagtggca aacaattcaa gaccatactt taaagatgca ttgtcttgga
     4681 tcgtgactgt ctccccatct tcagatgtat accattctcc tgcctgttgc ataatcatcc
     4741 ttactcgacc aaggtcagaa ggattgactt cagcgatttt ctttcccgtc ttttctttga
     4801 catctcgcgc tacttgaata tactcgtccc acttcagatt ctccatatcc tcttctgtat
     4861 aacctgcttc tgccatcaga tccgtacgat agaagtttgc tgttacgccc gaatcgaaag
     4921 gaacaccgta tattttatct cctactttgt ttaccgcaaa tttatacggt gcaaaatgat
     4981 cttcctttac aatagcagac aaattagcga atgcatctgg ataagaagtc aaatagcctt
     5041 gtatcctata atcttcaatc aagacgatat tgggcaatcc ttctgtattc ccgctcgcta
     5101 aagcggtgtt cagtttctga acgatatcat cctgagacat cgtaacaact tctatctctg
     5161 tttcttcgtt ctcataaact ttttttgctt cattcactgc tttgatattg aatgtctcat
     5221 cccacgccca gacagtgact ttttcttctt tgtctgctgt actactagca cttccgcatc
     5281 ctgttaagaa acctgatgct gccgctaaac aaacgactcc agcaattaac tttctgatgt
     5341 tcatttttat ccgctccttt tccatccatt agttgtttac gtttgctaca ttcatcatac
     5401 caaaatttga aaacggtttc tttattattc agatacttca aaaatttctc ctaaaataat
     5461 aaaaaaatac aaatcaacta tgacaaaagg aataatctta gcatctagac caaagatcga
     5521 aatggtgagg tttctttaaa ataaaaatat ccttgcattt tctcctagaa ataagtattt
     5581 ttaaattaca agactattct taaggcgggt aaaaaaatgc caatacgcgt aattcttatc
     5641 gatgatgaac agacgatttt agatggaatg aaacagttga tcaattggtc tgagcacggg
     5701 tttcaattaa tagggacttt ttccagtccg atgaaagcgc ttgatttttc tttggtacat
     5761 gcaatcgata tcgtggtcac agatgtaatg atgcctgaat taaatggaat cgaattatcg
     5821 cggctattaa aacagcaaca acctgaaaca cagatcctta tcctctctag ctatgatgaa
     5881 tttgatatgg ttaaagattc ttttaaagaa ggcgtcgctg attatctttt aaagcctcga
     5941 ttgagtcctg atttttttct aaattcctta actgccgttt cacaaaaaat caaaaaaaag
     6001 cccaacaaaa gcccaatcac caatcgttat gagcagatct gcgagaatct ttcacagcag
     6061 attgctggac aaactcgtcc attgcttgac cctcttcttt ttgaacacac cttgtttttc
     6121 tgttatatac cgaaaaacgg ccattcagtt caaaacaagg ctctaaacaa aaacagtcga
     6181 tcacccattc attgatggat agcgacgatt cgtttactat ttatcctgtt tctacctttt
     6241 cggaagaatc cggctatgta atcaatactg attccaaaga tacacttagg aagtttgttc
     6301 aaaagtttcg tcaagaagtt tttccaggtg atttttttgt tgtttctgat tcttttgcaa
     6361 tccaagatat caatgaaata ttccaagaga tcagaaattg caccaaagga caacgtttct
     6421 atcataaggg aaagaacctt gcttatcagc atgaacttct tccgttatta accaaccacg
     6481 agcagcaagc aagtagttat ttaacaaaaa tcgttcataa agactacgct ttagctgtca
     6541 aagaacttga gaatttcttc acgacgatat tggaacagcc tattgatcca gcttatttga
     6601 aacatgaggc aatcaatcgt ttctatgcat tactcaacgc tttggctgac gagcatgttg
     6661 ggaatgaaga actttctttg ctcaagatcg cccttccttc tttattagcc gatgctgagt
     6721 atttcgaaga tttttctatt cttgtcaaag aaacacttga gaaactcacc cacttttctg
     6781 caaatgcaaa aaaagacaat ttcgatatct tgactttgat ctacgagttc gtccaggaaa
     6841 attatgagaa agaaatcaat ttacaacttt tatccgaaaa atatcatttt tcatatagct
     6901 atctctcagc catctttact gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag
     6961 tccgtatcag taaagccaag ctctttttga cggaaacacg gcttactttg acggaaatct
     7021 gtgagaaagt cggctatacc gaactgggtt atttctccag agtttttaaa gaagagacag
     7081 gaatgacacc ttctcaatac cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga
     7141 gcatgaactc tttgccaaac ttctgttcat tttgttcatc ggtctttttc tgcaagccat
     7201 cgtcatttct ttgtttattt atcatcgatc aagggatgcc tatatccagc tgttcaatca
     7261 atcgaatgat gtggtactaa aaaagattca atctgaattt gaaagtttga atgatacaat
     7321 cgagaataca ttagccgctt ttgattctaa tccagctgtc aaaagctatt tttccaatga
     7381 tccagcccaa catatggaac agcttcagca actaagaaca atccaaaaaa tgaatgactc
     7441 tctttcaaaa atccatccaa tgatcgatta cgatgtattg atctttggag aaaatggaag
     7501 aacttttgtc ggaaacgaca tgctcactgc cgtatctgcc gattcttttt ttcaatctgc
     7561 gattgctcag agagtgaatg aacgtgctgc tgatacacaa atgctttttg cacaccacgg
     7621 attgactctt cgcgataaga aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac
     7681 attgaatcac gtttacggat atgctgtttt atcgatctca tccaagcaac tagcgaatct
     7741 ttttcaatct gtagtaaatc ctgagatatc gaagatctcc ttcatgaacg aagaacagac
     7801 gatcatcgca tcaaatgaag aaaatacaat tgggagccga tcaatgattt tcaaaaaact
     7861 aacagtaggt gaaacaacga tttcaaatgg acagcagttg acccgtcttc ctctgtaccg
     7921 ccaggattgt acattactca gtcaagtcga tcttcattct ttatctaacc aaatgggcgt
     7981 gatttttccg attattttgt ataatatcgt gacacttgct tttgctggct cattggtatt
     8041 tatgtatttg gatcgacaca caaaatcgat ctaccgcttg attgattcgc taaaacggct
     8101 agaggaagat ggcttaaaag ctactgttcc tgtacaagga agccatgaag tccaattgct
     8161 agggaatacg atcaatcaat tgctaagtaa tgctcagcat cattatgaac agacgatcca
     8221 agacgaaaag aagaaacgtt cgcttgaaat ccaaactatg caagcacaga tacagcccca
     8281 ttttatttat aatacgctga ctagcttgaa atttttgatt tggcagaaaa aaacagatga
     8341 agcagttcaa ggaatcgaca gtttcattac tttactaaga agtacgattg ggaaaaaaga
     8401 agaagtgatt ccagtcaagg aagaaatcaa aagcgtacaa agttacatcg atcttttgag
     8461 tatgcgatat ggcgaaagaa tctcggctaa aataatgatt cctgatgaac tgcagtcatt
     8521 atctatgccg aatatgatcc ttcaaccaat tatcgaaaac gcctatcttc atgcttttca
     8581 caataaaacg caaggattca tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt
     8641 cgaagtgatt gataacggcg atggcttcga tactgaaaat accaaacaaa aaaatgatca
     8701 tttttcagga atcggcatca gccatgtaga tgagcggata cgcctaatgt atggcgatgc
     8761 atatggctta acgatccaat cagtgattgg gacaggaacg actgtaacga tttgtctacc
     8821 gcttcttcct aaaaatcaat cagaatatca aaaataaaga atagccaagc gctgattttt
     8881 ttattttaag ttaaataaat caatcagtat tcttgacttt catctacgcg tctcttctac
     8941 tgtcagcact ggataacagc ccaatatttg actttctcct ccgagcatct tgatttcttg
     9001 gagcgcattc tctactaatg tcattggacg gtccaacaac aaatcgatca cgaaaaaata
     9061 ttctcccaag ctagttttca atggtcggga ttcaatctta cttaagttga tttcccgcca
     9121 gccaaaagct gccagcattt tatgaagcat ccctggccga ttagcaggta gtgtcaagat
     9181 gacactcatt tttactggag ctgactgctg gctggtcatc tttcggtcac cgacgatcca
     9241 aaaacgtgtc tggttcaact cattatcttg gatattctca gctaagatct ccaatccaac
     9301 atgctgtgct gtttctaatg aagcaatcgc tgctgcgtct tctttcggat gttctgctac
     9361 atacattgct gcagcagttg ttgattctgt tgctactaaa ggaacattag gataatgcgt
     9421 ttctaaaaac tgttgtgatt gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt
     9481 tgttgctgga ttgcctaaaa gctgctgctt gataggaaga acgatttcac ttttaacttc
     9541 gacttctgga tgtttggaaa gaagatcgat tgtgtgatga acagctcctt ccaatgaatt
     9601 ctctacagga acgacagcca gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg
     9661 gatggaagca tacgcagtca attgttctgt aggaaatagc tgacaagccg cctgataagt
     9721 gaatgaactt tctggcccta gatagctgac gttcatatgc ttttgatcct ttctataatg
     9781 gtatcgatga tcttttctgg tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct
     9841 tcataccaag aaagtcgttg tgccaataat gcttttattt cttctcttgt ttttccaaga
     9901 gctaaaggtc gaatagacgt ttcatcttgt tggatacgat caactagaca gtccgcttct
     9961 gcctctaagt aaagaacaat cggctgtgtt tttaaaaaac gccgattttc tgcactttgg
    10021 acaatccctc caccagtcgc gataattttg tcttcatttg acagctttct taaaatatct
    10081 gactccactt ttcgaaagct tttttcaccg taatagtgaa aatattcggc aatcgacaat
    10141 tggatatgtt cctcaatctt tgtatctaaa tctacatact ctttttgtaa acattgagct
    10201 aaccctttac cgattgttgt ttttccagcg cccatgaaac caatcagcaa aatgctagcc
    10261 atgagcttct cctcctgaca caagttctgc taaatcgtca aaaaatgccg gataagagat
    10321 tgaaacagct tcagctcctt ctagttcgca aggtccatca gctatcaaag cagctacttg
    10381 cagcatcata ccgattcgat gatcgcctct gctggacact tttgcgccat gcagaggtgt
    10441 cggcccatgg atgatcagac cgtctgctgt cgcttttatc tttgctccca ttttctgtaa
    10501 ttcttctgcc accgcatcaa ttctgttggt ttcttttact tttaattctt ctgcgtcttt
    10561 gatgatcgtg attccttctg cttgagtagc cactaaagct agaatgggca attcatcaat
    10621 cagacgcgga atgatttctc caccaatcgt tgctttcttc aaatgactcg tcttgacact
    10681 taaatcagcc gattggttct gttcattgtg attcgtctgg gtaatcgctg cgcccatctc
    10741 ctccaacaca tctaagatac cagttcttgt tggattgacc ccgacatttt ttaacaacag
    10801 ttggctttcc ggaacaagaa gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc
    10861 tggaacagtt atctgttgac cagttaattt ttgcggtccg gtcactatga tcgttttatc
    10921 ttccactgtg atccttccgc caaattgacg aatcatttct tccgtatggt tacgggaacg
    10981 ttctttttca acgattacgg atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga
    11041 tttgacttgc gcactggcta caggcatatt gtatcggata ggtgataaag agcgggttcc
    11101 tgtcacagtg attggtagat actggtcatt ttcttctcct tgcaagtcag cgcccatctc
    11161 gcgtaaaggt tccatcactc gccccattgg acgtttagac aacgaagcat ccccgaacag
    11221 agtagtcgta aaaggctgtc cagccaaaat acccatcaat aaacgtatgg tcgtaccgga
    11281 gtttcccatg tcaattgatt cggttggttg gacaaatgag tggctaccgc gaccatgaat
    11341 cttgatcacc tcttcctctt cttcgatctc gacacctaat tgttggaagg catgtaaagt
    11401 actcagacaa tcttctgcgc gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc
    11461 tccaaacatg atgctgcgat gggaaattga tttatctgct ggtatcctaa cagtccctct
    11521 taatccatgt atttgttgta ataattgcat ttatccagcc tcctatttga tccagcaatg
    11581 ataactggta ttagacataa tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa
    11641 actgatttgc agtattccta aaatatcttc cctggtctct tggatcttca aattaatcaa
    11701 agaaactccc gcttttccga tcagtccagt tacttctgca ataacgccag gttcatctgg
    11761 cacatcgata aataaatcaa aaaaggcagg aatcgcgcct tgcttatgga caggcaactg
    11821 gtctcgactt tcttttgccc gattgaaaaa agaaaagatt tccgattggt tctcagtcat
    11881 gatccattct gctatttgtg tcatttcttg ttgccaatct gccaatcgtt ccaataatat
    11941 ctgcttattg ctcaacaaaa tatctgtcca catgacagga tctgaggaag cgatcctagt
    12001 gatatctcga aagcctcctg ctgccagttg tttggctcgc ggatactctt gattgaattg
    12061 ttctgcctga ttgactaagc cagctgccag aatatgtgga aaatgactta gcattcctgt
    12121 tatacggtca tgttctcttg ctgtaagagt tacatatttt gctttggttc cgcaaaatag
    12181 ttcttgcagt ttttcaacat cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc
    12241 attttcaaat agtttagcat ctgctgcctg tatacctgat ttatgagaac cagccattgg
    12301 atgtccaccg acaaaccgaa gatttttctg ctcagcggat gtcacgactt gctgcttcgt
    12361 actgctgaca tccgtaatga tgacgtgatc agacaagttg attctttcaa ggacatcaag
    12421 ataagctaag gttgtacgga cgggaacggc taataagata acgtctgctt gttctgcacc
    12481 tgtttcaaaa tcacttgcaa cgtaatcaac gatctgctgt tctactgctt gctcacgggt
    12541 ttttgactga ctatcccaac caactactat cagttctgga ttggtctgac gaatacaaag
    12601 tgccatagaa gcaccaatca gtccaagccc cacgataaaa acatgttgtg ccatcttatt
    12661 tgcccccttt ttagtaatgt ttcaagtagt cacggtactc cttcactgca gctttcaact
    12721 caacaagcga atcacttggg aattttgaca atagctctgt cgctaccaca gtggctacaa
    12781 cattttccgc aacgacgcta gctgcaggaa ctgctgtact atccgaacgt tctacacttg
    12841 ctttgtaagg ttcttttgta tcgatatcaa cactttgaag tggcttgtac aatgtaggaa
    12901 tgggtttcat gaccccgcga atgacaagtg gttcgccatt ggtcattccg ccttcgaagc
    12961 cgcctagatt attggtacgt cggaaatagc ctctttcttc ttcccatagg atctcatcca
    13021 tcacttctga gcctggtaat gaaccagaag tgaatccgac cccaaattct acgcctttaa
    13081 aggcattgat actaaccaca gcttgtgcga ttttggcatc tagcttcgtg tcccattgta
    13141 cgtagcttcc taatccagct ggaacgcctc caacgagcac ttctacaatt cctccgatcg
    13201 tatctccatt tttctttgtc tgatcgatca aatcttttat tctttgctca actgctggat
    13261 caacaactcg tacttctgac gcttcagaaa tttctttgat ttcttgaatc gagatatttc
    13321 caggtatttc tgcttggatt ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa
    13381 gttcttccag aattttcttg gcaattgcgc cgattgctac acgcatggtc gtctctcttg
    13441 cagaggaccg ttcaagcaca ttccgaagat ctcgatgatg gtatttcata ccgcctacca
    13501 aatccgcgtg tcctggacgc ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca
    13561 cttctgctac agacatgaca gttgtccaat ttttccaatc tttattttct accactaaag
    13621 tgacaggtga accaattgtt ttgccgtgac ggatgccaga cgtgatccga acacgatctt
    13681 tttcgatctt catccttcct cctctgccgt aaccagcttg tctgcgagcg agttcgtgat
    13741 tgatttcttc ttctgacaga ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt
    13801 ctggtccatg ggattctccc gcagtcatat aacgcatctt acagtcctcc taagtaatct
    13861 ttgaatgtct ctgtgggaac aggaacgatt tttgcttgcc caatcttttc tagcaagatg
    13921 atattcaatt ggcttcctct tgctttctta tcatgggtta tcgcgtggaa taattcatct
    13981 ggatgactta gatcgtacgt aatcggcaga tggaattttt gaagtatcct ttctaaagca
    14041 gctgtcgatc cagttggaga caagccgatt ttttctgcat gagaagtgat ggctaccatt
    14101 ccaatagcta ctccttctcc atgactgact accccatatc ctgctgtatt ttcaattgca
    14161 tggccaattg tatgaccaaa atttaaaata agtcgatttc cttggtcaaa gacatcttct
    14221 tccactactt ttcgtttgat ttccaacgta gcagtaatga ttggaacagc atgttccaga
    14281 agatcttttt cgtctttcag ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct
    14341 gctgatttga tgatttcagc gattccttct cgtaaacgac gtaccggcaa agtttttaga
    14401 acctcaggat caatcaatac accagctggc tggctaaatg ttccgacaag gtttttcgct
    14461 ttgtttgtat tgactgctgt cttcccgcca atactagaat ctacttgtgc aagtagcgta
    14521 gtcggaattt gaacgaaatg gatcccacgc atgaacgtcg aggccacgaa tgctgctaga
    14581 tcacccacca ttcctccacc aagtgcaagt atcccatcgc tgcgggtaaa atcattatct
    14641 gctaaaaaat cgtataactc agctgcttgt tctaaagatt tactggtctc acccgccggt
    14701 acgattgaaa ggactggttc aaaattagct tgtctcaatt ggaacatgat tttttctgca
    14761 tatagtggag caacgtttgt atcagtgatc acagctactt tttgaggtct ccaaatcgtt
    14821 tgaagccatg atccagcctg ttctagtgcg cctttttcaa tatgaatatc gtatttttgg
    14881 ttatcaacat gtacagtaag cattcgtttc acttctttct tttaaaaagc tggaattaat
    14941 cgagtgtctg aatcttttcc attgcttctt tcatgatcgc aacttctttc atcatgcgtg
    15001 agtaagtctt ttcattcaac gattggggac cgtctgacca agcatttgca ggatcaggat
    15061 ggatctctac gatcatgcca tctgctccgc ttgccacacc cgcacgagcc attggtggta
    15121 caagttccca aattcctgta ccatgacttg gatcaacaat cacagggaaa tgagttaatt
    15181 ttttcatcaa tgggacagca cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc
    15241 gaatcccacg ttcgataaaa atgacaggag atttgtcttc gactgcaatg tattctgcag
    15301 cattaagcca ttcattgatc gtaccggaaa ttccacgttt caatccaaca ggtttacctg
    15361 ttttaccgac agcagatagc agtttaaaat tttgcatatt acgtgcgcca atctgtagga
    15421 tatcgctgta ctcagccacc atatcgatat gcccttcatc catcacttca gtaatcactt
    15481 tcattccaaa ttcatcagcc gcttgacgga tgtatttcaa tccttcttct tctaaacctt
    15541 ggaaagcata tggagaagta cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc
    15601 cggctttggc cattcgcgca cattctctga tttggtctaa tccttcgata gaacaaggac
    15661 cagccatcgt cacgaaactg ccgtcaccaa tttttactcc gtctacatcc acgactgtat
    15721 tgccaggatg gaattctcga gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt
    15781 ctactccttc atagcgtgta aatgctcctt cttgtaaact tcgcgtatca ccttttagtc
    15841 caatcactac tcgttctgtt ccttgatcga ttgagacttt gaatccttct ttttcgatat
    15901 gatcgacgac tttttttatt tgttcttccg ttgcttcttt tttcataatt actatcattg
    15961 tttttcccgc tttcttttgt ttacttatct atcttggctg attttctcta ctttttcaag
    16021 gtggttttac attaattcct actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt
    16081 ctttcctact tatgacccag ataatcaaca aaaaaagatg tccctgtagg aaattgcctc
    16141 tacagtgaac atcttcaacg agccttaaaa agcgctgcaa aaatataaaa tagccactat
    16201 agatgaattt ctctacgtgg ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac
    16261 aaacctggtt tgtttgtacc cacgaagtca tgaatacaaa cctatctaaa atagctaaag
    16321 taatacgtat tcagttttgt aagttttcta gatttcataa aaaatcgctc caaactgatg
    16381 taagaattgt acctagtata gacataaaaa aatcgactgt caatcatttt tatgaaactt
    16441 tttttaattt tctgatagtt aactttgttt ttcagaaaaa taacaattgg ttttattgaa
    16501 gaaaatagtc atgaacaaaa gtatctgaga acttttttac tctcttgttc atgacatata
    16561 gaataaagca gctttgtctt gtaaactccg tttttcaaat aataatctaa agattgctac
    16621 tgaataataa agccgatttc atggtcctct tcgctgctga ttcggtaagg tgactcaaca
    16681 tccgctcccc agctattgat acccccgact cctcttactt ttgcaaaaat cgtaagaacc
    16741 gttcgtcttt ctggcggtag ttcttctata tgtgttgcct gttccagttc ttctgctttg
    16801 aatggtaaag cggaaaaagc aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct
    16861 tcttgatctt tatccgtatt atccaacgtt tgatttcttg ttagttctac ccatttcgtt
    16921 tccatatgca tgccgcattc ttggggaaca aggtatgggg aaacggggag tcctgccact
    16981 ttataaatac cttcgacacc accagccatc cgatccggat atgtttcccc tgataggcct
    17041 tcatactcaa aaaattttgc tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat
    17101 tccggtaatc ctttttgtcc ataataatgc atattgacaa gcattttacc ctctccagcg
    17161 atttggtagg aaattgtcac ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg
    17221 atttcaaccg tttcagcgta ttcattactt gaatattgat tatttactgg agcaatcggc
    17281 aaatcgatct ttttattgtc caccagtact tctatttctt tgacttttgg atacaatccg
    17341 gctcctaacc acataccgga tttaaatcca aatccgctac ctctgtcatt atcggtcgtt
    17401 gctcgccaaa aaactggaag tgtttcccgg tatagccatt cttttccgtt tttattgagc
    17461 gattccagtc cgcctcttgt ataagaaaaa atataatgcg tattccccga tttgacacct
    17521 aatgtacagt cgccgaagac gattgcaact ttttccgtat ccatatgact tttatttact
    17581 gtatttttca taataatatc ttacctcctg catggcgggt ttttcttgtc catctgcaaa
    17641 aacgatccca ttccctgaga attcatagtc acttggttta tcgtcaaagt caccgccata
    17701 gcgcatcact tctctgcctg tgattggatc agtcacttgg atcgcctgat ctttaaaatc
    17761 ccatatatag cctccttggt acatttcata acgatcaagc aacgtcatgt aagaatccat
    17821 tccacctaac gaattcccca tgtcatgcat atattcacat aagatgaacg gtttttccgc
    17881 tttattttca aggtagtcaa tgatctcttc tggtggcgca tacatgcagc tttttacatc
    17941 tgaaatcgaa tcttcgaatg ctggatttgg aaaattccct tcataatgga caagtcgatc
    18001 ggggtctact tttttgaagt aatcgttcat ttgtcgaatg ttttcttccg cataagattc
    18061 atttccaaga gaccaaaaaa gaatacttgg atggtttttt aatgtttcga aattcgtttt
    18121 tgctcgatca agaacagccg cctgccactg aggtactgca cctggtacgt tgtaagaagg
    18181 ctcaaatgcg cccatttttt gccatgagcc atgggattcg aggttcgttt ccgccatcac
    18241 atggattcct gcttggtcgc ataaataata ccaagtgatc tggttggggt aatgagatgt
    18301 ccgtacgccg ttgatctttg cattttttat gatagccaaa tctttttcca tatcttctat
    18361 agtgatggcg cgtccttttt tcggatgcca ctcatgtcga tttaccccgt tgataatcat
    18421 ccgttttcca ttgaagtaga tgattttatc tttgatttcg attttacgaa aaccgaagga
    18481 atagtcaata tactccgtta ctcttttttc ttcgtctatc gtctccaatt caagcttata
    18541 taaattgggc tgaaaatgcc cccacagtgc cacattttca aatccatcga tgcgaatcgt
    18601 catttgctct tttaacggat attgctgttg atagatttcc ttcccatcag gatctagtat
    18661 cgctacattc agctgactgt ttttggctac ttgctcaaaa gacaaatcta cttcaagttt
    18721 gccattttga catttgtcat ctaagcgagg tttgatccaa agatcttcta aatggttttg
    18781 tcctcgagca actaagaaga catctctgaa gatcccaaaa aatcggaaaa agtcctgatc
    18841 ttccaagaat gcagctgtac ttcttttgta aacctccaca gctagaatat tttcttcttc
    18901 caaataaggt gttaaatcaa attcagacgg agtgaacgaa tcttcggcat acccgataaa
    18961 atgaccattc aaccaaataa acattgcttg ttctacacca gcaaaatgaa tcgagatttg
    19021 ttttcccttt agaccttctt ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc
    19081 tttagcagct gaaaagatcc cttccgcctc tttctcaggg cttgtcgtga aagggggacg
    19141 gcgaaataca tgtccctccc acggatacat cgtattgatg taatggatct tgtcataatt
    19201 tgctaattca atatgactag gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt
    19261 tttataaaat gtttttggtc gtaccgaagg atttggcgaa taacaaaaac gccatgatcc
    19321 atttaaagac tgtttaaggg aggatgtggt ttctacttct tcccttgttg cataacaaac
    19381 atgatcgcta tgtgcatttg attggttcac tctaaaaact tgtggatcat ctaaccattt
    19441 tatatttgct ttcatacttt tttccttctc tctcataact ttttgaaatg aagcagttct
    19501 gtttggaaat caccttgaaa atcggggaag taaagtccaa ctgtcatcaa ttcggccccc
    19561 gaaaatatcc gcttcgaggt ctgttcctga taaagtgcct catcatctaa ccccatcaga
    19621 tatacttcat ggaacgctgg ttgagctgaa gctagtatcc tccctaaaaa cacaatagct
    19681 tcatcttgtt taggagacac aaacatccat gcggcaatat tttcttcaaa aggactcgcc
    19741 aaacgataat aatggccata ctggatcacc ggacgaatcg tttgatagga tataatttgg
    19801 tcttttactt gctttttttc ttcaggagac agctttgtca aatccagttc ataaccaaaa
    19861 acagcgctca tagctgtttc tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga
    19921 tttggtacag ctgatacatg agctgtgatg gacgaaatcg gataagcaag gcttgttcca
    19981 tattggattt tcatacgctc cactgcatcc gtgttatcac ttgtccatga ctgcggcata
    20041 taataaataa acccggcatc aaaccgtcca cctccaccag aacagccttc ccataagatt
    20101 tccggataat cagttgtcaa atgttcaagt agttcataaa gcccgagcat ataacgatgc
    20161 gctacttctc cttgtctctg tgggtcaagg gtaatcgaat agacatctga aagcgaacgg
    20221 ttcatatccc atttgatgta gtcaagagga atcgtatcta aaatctttct catttgtttc
    20281 tcaatcgtct gccgaacatc taaccttgta aaatccagta catgttgtga tctggaagca
    20341 gaaggcattc tacctggctc ctgcataaga aaatcaggat gtgttcgata cagttcagaa
    20401 tcaaccgaga tcatttcagg ttcaaaccat aaaccaaatt tcaatccttt gctatgagca
    20461 taatctgcta tttcacgtaa tccatttgtc aacttgcctt catactcgaa ccagtctcct
    20521 aatgaagaat tgtccgcatc tctttttcca aaccagccat catctaatac gaacatttcg
    20581 atgcctagct cctttgcttc atcaatgatc gccttgattt tttcactatt gaagtcaaag
    20641 taagtggctt cccagttatt gaccagaatc ggccgttcag caaattgatg acgacctctt
    20701 gcgattcttt cacgtagcaa ctcatggtgg atctgactca ttttgttcaa tccctgactt
    20761 gagtaagaaa ggatcatttc aggtgtttga aaagactggc ctgcattcaa ttcccacgaa
    20821 aaacgatggc tgttgatccc accgacgact ctcaattgat tgatctgatc tttttcaagt
    20881 tcgaaagaat ggttgccgga ataaacaaat tgaagtccga tcgcttctcc agtattttct
    20941 gtcgtatgat gatgaactaa agcaataaag ttattcatat ggtgactgct cgttcctcga
    21001 cggctttcaa atacttttgt tccagataaa acagattgcc gtgaaatctg tctttcattg
    21061 acatgtgctc ctggcaaagc aatgacttca tcaaatcgcc tagtatgggc aaagtctagc
    21121 tggaaactag ccgctttttc tagtttgatt gtttctccgg tttcatttct tatctttaca
    21181 gatcgtgtga tcactgctct atcagtaaat atggtataga acaaatcgaa ataaatcgct
    21241 gtttctctat ccttaagtga aatcaccaac gtttgtgcct ctgacttgtc catcacataa
    21301 gtttgaggca agccttcgat ctctggcttc ccatctgtaa tataatggct gtcatatctc
    21361 agatccagta agtctgatcc attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc
    21421 atgctgccat gagaagagta ttcttgcggt agtgtatctt tcgacagaga ccggtcagga
    21481 tttaagggaa catttcctga aaatccacga tctcttcggg gataattttt attgtctttg
    21541 tactgcttga ctggtttgcc aaaataaata tgcgccaata cattgctttc ttctatcttt
    21601 atcagataag aaagaaatgt atttcgtaaa tggaagactc ggctcttttc atcaaataag
    21661 atgaaatttt tatctgtttt tctatgcgta atatccatca tttcactccc aacaaaacgg
    21721 aaaccgttta ctttttttta taattcctgt atactgttta ctaaacaatt ttgtcaataa
    21781 aaatttttta tttttttgag gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa
    21841 aggcaaatgt ctctcctgct acagtttccc gtgtgttgaa taacgatcag acgatccatg
    21901 tggctcagac tactcggcaa cggatagtag aggcagctgc tgcgttggat tatgacatca
    21961 gtactcgtaa atatatcaaa aagagaatgc cttcgattgg tgtgatctct acgatcggca
    22021 aagcgagcga agaacaggat atctattaca aacatttgcg agtagggatg gaagaagaag
    22081 ctcgacgtct gcatttaggg atgaatcgaa tctataatct atctgataat cctaaacaat
    22141 gggaagatct agatcagtta ggtgcggtga tcgttgttgg gactgttacg aaagaatcga
    22201 ttaccgcctt gttaaaacaa aacatgcaaa tagtcgtcgt ggataaccct gacatccagc
    22261 aagaggtcga tatggtgtat gcagatcttg aacggatgac taaaaccgta ctggaattgt
    22321 tcttagaaaa tggtcataaa agaatagcct atatcggggg atataaagtc gatatggatg
    22381 aattcggtgg gaagcagatt tctataaatg aaaagaggat gcgtgcctat cagcatttta
    22441 tgatcgatca tcacttagaa aaatatatgt cttatcatct aggtggctgg acagaaaaac
    22501 aaggtgaggt acttgcgact aatctattag aaaatgaatc ccctcttcct actgccattc
    22561 ttgtcgggag cgatccaatg gcaattggtg tctatcgggc attgaaacaa aaaaatatcc
    22621 aaattggaga agagattgtt gtagcaagct ttgataatat cgagacaatc gcaaacctct
    22681 cccctggctt gaccagtgtt caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa
    22741 tggcattgga gcgaattgac ggtatacggg acgaaccaat cattttgact tatcctgcac
    22801 gattgattgt tagggaaagt tttatcccaa gaacaaaaag gtattgaaag agaggttgtg
    22861 aaaagccgct tcgtttcttc atactcaaaa cgaaacggct ttttcacaac ctcttactta
    22921 tacttattca caaaatccaa tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa
    22981 tcaaattggt attcatgggt aatctctttt tttgtatctg tataaaacaa ggattgcacg
    23041 ggtaccttta attctgtcaa ccgattttct aatgcttgac cttgctcctg gaatgagtat
    23101 gcatttccgt cagttatata cgttggcgga aattccttag aaacatggtc agccacacta
    23161 gcttctttca attgctcact cgttttccaa tcttttgttc caatcaacga ccacgcaacg
    23221 gttttgacga aaaacttcat aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa
    23281 tcaacaggtc cccaataaga aatggttcct ttcagactat cttttggaag tagctgtttg
    23341 attttcattt gtttagcata cgcatcattc gtttgtatag ctgcatattg caatgcgatt
    23401 tgtgaacctg cactatctcc accaaaaaat aattgttcca tgtctagcaa tttgtcgtct
    23461 ttttcttcag ctaataaatc tttgatcagt tcattcactt gaagaacttg attagggtat
    23521 tctgaatcag gcgctaattc ataattcatc gcaaccactg cgatgttggc gtctgaaact
    23581 aattttgtcg caaattcttt gacacccgat ttatctccgc cgacgaatcc tccaccatgt
    23641 acccaaaata gaacaggaac aggccccttg ctgttttttg gatagtagat gtcataagta
    23701 ttctctttat acttggactc atacgtcaaa tctgtttttt tcgccacgtt tttttctgct
    23761 tgatcgaacg tttttttatc agtgatttga acagtatttg aaaacatatg gttgatcaag
    23821 aatgctccag gtctggggga aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga
    23881 atgattccga agaaccatcc gataaattta agaattttct ttttcataag gctccctcag
    23941 tagttagtat taagcattct gattatacca tagtgttatt tcctatcaag ctctcctaga
    24001 tgatttaatg attttcccca aacttcttct gcaatgcttt tgacaaaaga aattttttcc
    24061 attgttcttc aaacaaaaca ttttcttctt ctgttgaagc aaatccacat tgaggactta
    24121 agcacaaacg atccaaaggc agatatcgtg tcgcttcgta gatccggtca atcacttgct
    24181 ggtgctcttc catttcgcca tttttcgtta cagtcaaaat ctaagacaac taatttatct
    24241 tcagagactt tctctaaaag aacaaaactc ccagcacgtt cactatcgta ttctaaataa
    24301 taggcacgga cattttcttg agtaaaataa tgggtctgct acgtcgtcat cccccctgat
    24361 gccgccaaaa tcgaataata atttccgcgt caaacatgta tatttagtgt tgaatcattt
    24421 gagaatatga aaataaaaat ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa
    24481 atctgagaca gaatgacgtt cattctgacc cagatttgat tttgcacaac tcaacagtcc
    24541 ttattggcaa atcgccaaaa taatgtagac taactaaaa
//
LOCUS       DACGMI010000043        24270 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.044, whole genome shotgun sequence.
ACCESSION   DACGMI010000043 DACGMI010000000
VERSION     DACGMI010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.044"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..571
                     /locus_tag="IXT46_001947"
     CDS             <1..571
                     /locus_tag="IXT46_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4947850.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            575..1216
                     /locus_tag="IXT46_001948"
     CDS             575..1216
                     /locus_tag="IXT46_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4947851.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1213..2130
                     /locus_tag="IXT46_001949"
     CDS             1213..2130
                     /locus_tag="IXT46_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4947852.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2127..2798
                     /locus_tag="IXT46_001950"
     CDS             2127..2798
                     /locus_tag="IXT46_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4947853.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3339..3827)
                     /locus_tag="IXT46_001951"
     CDS             complement(3339..3827)
                     /locus_tag="IXT46_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAQ4947854.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4028..4294)
                     /locus_tag="IXT46_001952"
     CDS             complement(4028..4294)
                     /locus_tag="IXT46_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAQ4947855.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4294..4557)
                     /locus_tag="IXT46_001953"
     CDS             complement(4294..4557)
                     /locus_tag="IXT46_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4947856.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(4550..4822)
                     /locus_tag="IXT46_001954"
     CDS             complement(4550..4822)
                     /locus_tag="IXT46_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947857.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            5033..5218
                     /locus_tag="IXT46_001955"
     CDS             5033..5218
                     /locus_tag="IXT46_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4947858.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5360..7183)
                     /locus_tag="IXT46_001956"
     CDS             complement(5360..7183)
                     /locus_tag="IXT46_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAQ4947859.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7781..10486)
                     /locus_tag="IXT46_001957"
     CDS             complement(7781..10486)
                     /locus_tag="IXT46_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAQ4947860.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10792..11739)
                     /locus_tag="IXT46_001958"
     CDS             complement(10792..11739)
                     /locus_tag="IXT46_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAQ4947861.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11929..12198
                     /gene="rpsN"
                     /locus_tag="IXT46_001959"
     CDS             11929..12198
                     /gene="rpsN"
                     /locus_tag="IXT46_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAQ4947862.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12374..12736)
                     /locus_tag="IXT46_001960"
     CDS             complement(12374..12736)
                     /locus_tag="IXT46_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4947863.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12747..13868)
                     /locus_tag="IXT46_001961"
     CDS             complement(12747..13868)
                     /locus_tag="IXT46_001961"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAQ4947864.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13884..14234)
                     /locus_tag="IXT46_001962"
     CDS             complement(13884..14234)
                     /locus_tag="IXT46_001962"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAQ4947865.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14364..15875)
                     /locus_tag="IXT46_001963"
     CDS             complement(14364..15875)
                     /locus_tag="IXT46_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAQ4947866.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16197..17549)
                     /locus_tag="IXT46_001964"
     CDS             complement(16197..17549)
                     /locus_tag="IXT46_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAQ4947867.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17702..18778)
                     /locus_tag="IXT46_001965"
     CDS             complement(17702..18778)
                     /locus_tag="IXT46_001965"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAQ4947868.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18974..20719
                     /locus_tag="IXT46_001966"
     CDS             18974..20719
                     /locus_tag="IXT46_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAQ4947869.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(20999..21436)
                     /locus_tag="IXT46_001967"
     CDS             complement(20999..21436)
                     /locus_tag="IXT46_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAQ4947870.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21420..22793)
                     /locus_tag="IXT46_001968"
     CDS             complement(21420..22793)
                     /locus_tag="IXT46_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947871.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23115..23603)
                     /locus_tag="IXT46_001969"
     CDS             complement(23115..23603)
                     /locus_tag="IXT46_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4947872.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23625..24227)
                     /locus_tag="IXT46_001970"
     CDS             complement(23625..24227)
                     /locus_tag="IXT46_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAQ4947873.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6959 a         5163 c         4488 g         7660 t
ORIGIN      
        1 agcaagccgt atcgccatca tgagtgaagg ccgtgtgatc caatttgata caccagaaaa
       61 tattttacgt catcctgcaa acgatttcgt agaagagttg attggagaag atcgcctact
      121 acaagccaag ccaaatgcga caagagtcgg cgaagttatg ctaaatacag caatcacgat
      181 tacaccggaa aaatcattac aagaagcaat caaactgatg agggaaaaac gtgtagatac
      241 gttgttagtt accgataatt cgaatgtatt aaaaggattt atcgatgtag aaacgttgaa
      301 taaaaaacga ggaaaagtat ccagtgtcgg cgacattttg aataaacatg ttttttacgt
      361 aaaagaatcc gcctatcttc gtgatacctt gcaacgcatt ttaaaacgcg ggctgaaata
      421 cgtgccggtc gttgatgaac agaacaaagt cgtaggtatc ctgactcgtg catcattagt
      481 ggatatcgtc tacgatgtga tttggggaga agatcccgca actactgatg ttgcagagtc
      541 agctactcct gaagaatcta aggaggtctg acctatgcag cagttttttc atcagcacgg
      601 ttcagaaatt ctctcaaaag gttttgaaca tctttatatt tcaggacttg ctttgatcat
      661 tggtatcatc attgctgtac cgcttggtgt cttactgaca cgttttccaa aagctgccac
      721 gattgtgatt ggcttaacca gtgccttgca gacaatccct tctcttgctt tattggcatt
      781 gatgatcccg ctatttggcg taggtaaatt acctgcgatt atcgcactct ttatttattc
      841 attattgccg attttacgta atacgtacat tgggatgaaa aatgtcgatt ggaattatcg
      901 ggatgtggca aaaggcatgg ggatgactga gttccaatcc attttttccg ttgaattgcc
      961 cattgctatg ccaacgatca tggctggtat tcgtttagct gccgtttacg tgattgcatg
     1021 ggctacactt gcctcttata tcggcgctgg tggtttaggc gatttgattt ttagtggact
     1081 gaataattac caaccagatc tcattttggc aggtacgatc cctgtaacaa ttttagcact
     1141 attggctgat tggcttctag gtctcttgga acaccggctg acaccgatcg cacttagaga
     1201 ggagaatgaa gaatgaaacg tatactaaaa atgaccatgg ttcttttctc tcttcttata
     1261 cttgcgagtt gttccttccc tggtcttgcc agcaatacag atgaagacac catttcgatc
     1321 acaggtggaa tcacttcaga agcacagatc ttagcaagtc tagttgccgg aatggttgaa
     1381 cattatacag ataaaaatac cgcaatcatc aacaatctgg ctactacaac tatcaaccat
     1441 caagcgatga tgaacggaga tgcttcaatt tcagcggctc gctacacagg aacagattta
     1501 acgactacat tgaaccttcc tcctgaaaaa gatccgaaaa aagcgtttgc taccgtgaaa
     1561 gatgaatttg agaaaagata cggtcaaacg tggttcccgt cctatggttt tgaaaatacg
     1621 tatgtctttc ttgttcgaaa agacaccgca caaaaatacc atctatctaa agtcagcgat
     1681 ctgaaaaatg tagcggatga attagtagct ggtgtagata cttcttggat caatcgtaaa
     1741 ggagacggtt atgacggctt ccaagaaact tatggcttct ccttcaattc gatattacct
     1801 atgcagattg gacttgttta tgacgcagtc gaagcaggaa aaatggatat tgttcttggc
     1861 tactctacgg atggacggat cgccagttat gatctagtca tgttggaaga tgatcgtcaa
     1921 ttcttcccac catatgatgc tgctccagtt gtagacaaca agatattagc tgatacgcct
     1981 catttaaaag aagccttaaa taagttaggt cataccatca gtacggaaaa aatgcaggaa
     2041 ttgaactacg aagcagataa taatctagtg gaaccatcag tagtagcaca acgtttctta
     2101 caagaaaacc actattttga agggaagtga agcaattgga taaaatgaat gtctttcaac
     2161 aatttttcta ttatttccag gaaaatggct cctatatctt tgcacaattt atccgtcact
     2221 tcctgatttc tatctatggt gtcctctttg cagcagttgt cgggattccg gttgggatca
     2281 tgatttctag gagacgtaaa ttagcaaact gggtgattcg tttggcgaat atcatccaga
     2341 cgatcccttc tctagccatg atctccattt taatcattgg attaggcctg ggagtcaatg
     2401 tcgtgattgt tactgtattt ttgtattccc tcttaccgat catcaagaat acgtataccg
     2461 ggatgatcca agtagacaaa aacatccttg atgtcggcaa aggcatgggg atgactgcta
     2521 gacaacgact attcatggta gagttaccac tctctgtttc tgttatcatg gcaggcataa
     2581 gaaacgcgtt agttgttgcc atcgggataa ccgcgatcgg tgcattcgtc ggtgctggtg
     2641 gtcttggaga tatcattatc cgaggaacca atgcaacaga gggcacatcg attattttag
     2701 caggtgcatt gccaactgca ttaatggcga tcatcacgga ctggctttta ggtattttgg
     2761 aaagacggct agatccagcc agccgtacat cacgctgatg ttattgtaaa aaacaaaagc
     2821 ttctgcgacc atttgttggt cgcaaaggct tttttagttc tgtcattttt aaggcaataa
     2881 tccactctga ttcttccctc cttatgggca aagagttgct tttcttagct atttatccat
     2941 tccgtatact ccaacttcat actgccaacg ggttcatatc tgcatccacc gactaagttt
     3001 ttttcttatc cgctaaggca ttttgccaat ccattttccc atcactcgtc atggaattca
     3061 taccacatga tctctaaata ctcgtctgct tgttctttga attgggcatc aattcttaca
     3121 tcctttggcg tggctttcat ttaagccttt tccatcagtc ctcgattgtt cgatgccttc
     3181 agctgcatca tcaaaactgg tgactgccgt atcggtaact tcgatcatct tttatacaat
     3241 cgggaacttg ccatcctcat ccttggctaa aaacatatct agccattcca gcttctcgcc
     3301 atgggaggtt tgcggttcct aaaaccggta cacgattctt atggactgca tccgtcgcaa
     3361 ctagacttgg cgatacgatg atccttcacc agaagagcac ccccgtaaac caattgatcg
     3421 atatattgcc aataagaaaa gacattggcg taaaagatat cgatccctcg tgatgcattg
     3481 ccgttgatac tgctattcat ggccgaaagc gccacgactt taacttcttc cgtttgagtg
     3541 acattcatgt tcggcaatgt cgctttggat acccgctctg ctaaaggaac gacactggta
     3601 ttgtatttcg tatctgtatc ttttccaaaa gaccatgcca acgaatcctc tgggaaccaa
     3661 taagacgact ccggttgatt gtccattgct tttttcaaca tacttttggc tgtttctcga
     3721 taaacgacat ttccaattgt cttcgcctca ctttggcgat aatcgatggt cgttgccact
     3781 gccaacacta acaacgatgc tccaatttta ctgattttcc ttgtcacact tcttcctcct
     3841 tgttttacat aaacccgtca acattccatt cctaaactca aacaatgacc cttcaaaggt
     3901 ggagatatag gaacaaatta aagaaatcat gcaataaatc caagaaggtt ggttttagaa
     3961 caaaaaaaga gtctcctttt tggggagact ctttgttaac tatctaaaaa ggttggctct
     4021 tctcacttca ctcataatgt gtccaggcag aataaatttc tacaacttta ttttcctcat
     4081 caactttgta aaccactcga tgctgtctat tcagcctgcg tgagtatctg ccttcatgtg
     4141 taggtctcag cttttcaaaa gactgcgtgg gcatatatgg atcttccttc aatgtctgaa
     4201 tcacttcttc aaattgtttc tttaaattcg tttgcttgat ttttcttaaa tccactttcg
     4261 cagagttttt gattgcgact gtatagttac tcatcaaaga gcttcccaat caatatcatc
     4321 gatattcgta aagctactgt cgtctttttc gcggtctcgt actttatcta aagtacctgt
     4381 ttgctcaaga aaaagggttt cttgaatcgc tctccagtct tccagcccaa tcaatacagc
     4441 attgtttcca ctacgatcac taataatctc gatttcagta tgattttcat ttacctcttt
     4501 caataactga taaaaatttt tacgagcagt gctaggattc atcgttgtat tagccattgt
     4561 ctctcctcct ttttctgata taattatagc gtacttgatt aagtacgtca aaaaaataca
     4621 ataaagcact taaattcagc aaacttttcc tcttttttac atagagaaaa agaccccttt
     4681 ttagggagga tctttgtcca cgctcacttc ttactccttt acgactagcg gtagccaaac
     4741 gtaaagtaat tggtaacaac gtatcatctt tagcaaaggt cgaatccaaa gcctgtgagt
     4801 ctatgcaaca acaccaatac acgaaggttc ctcgttgcag tgtgacttga ttgatatctt
     4861 gaataacctg aggatacgca cgaaagattt gtaacggtta ttcaaaactg attttggccg
     4921 tcaagtcttc tactgcctca aaaatgattg cctctttcgt ctcctgtcat tcatgttcac
     4981 tatcgatttg atacttgctt agaccgttgg gtttgtgaat caccaattaa aaatggcact
     5041 gagttatggt aacaaaaaat ggtcacttga cgaggctgag attcctactt atgaagacac
     5101 atggcactta agagtcgagg taaaggaaga agctgaaaat ataggaggct gtacattatt
     5161 tggcaaagga ttcggaaatt atgatcaaga catcaaaatc aaaatgtttt acagctaaat
     5221 aggaagaata ataacatttc atacgctgtt cccatcttta atggcttata gagggcacct
     5281 ttagctgaga ataagacaaa acagaccctc tagcttcaat taagagctag agggtctgtt
     5341 tttgatttta aaacttggtt tatttcttca aatggtagct ataggtgctg acaacgatat
     5401 tttcacgcca agacaatcgc aatcttaacc gcaaacttgt ttggttatgg agaatattct
     5461 gccagcgtct gtttggtaca aattgaggaa tcaacacagt agttgtatag ttttgtttcg
     5521 ctgcattttt acttacgata tctacataac ggataattgg attttcaatc gagcgataag
     5581 aagagtggac gattgaaaaa cggacatctg ggaaatgctt tttaaattct gcttcgattt
     5641 ctttttcttt ttcgacatct tcgtctagcg aaacatgcat cgcaacgaca taatcaccga
     5701 tcgaacgtgc gtaattcaac gcaccgatat ttacccgtgt cacattcccg actaatacaa
     5761 gaacggtatt cccgtcataa tcatgtagtt ttgcatcatt ttctaaacga agctgttctg
     5821 ctactttttt ataatgatca tggatcttat aaaaaatgaa cataacgatt ggcataatga
     5881 tgaagaaagg ccaaatgtcc cctaaccgat agacaaacaa aatcgcaatg attgcatatg
     5941 agatgaacgc acccgtaata ttggcaatcg atttgcttaa ccatcttttt ccttcttttt
     6001 tccatttgac gaccatccct gtttgagata aagcaaatgg aatgaacacg ccgatagagt
     6061 ataacggaat caagcgttct gttgagccat ggaaaataaa cagcaatacg atcgaaccta
     6121 gcgctagtgt gataatccca ttggaatagc ctagtcgatc cccacgatct tgatacatgt
     6181 gaggcatgaa tttatctttt gccagattgt atgcaagaac tggaaaagca gaaaaaccgg
     6241 tgttagcagc aactgctaaa atcagcgctg tagcaaattg aaggacgtaa tacaaaatac
     6301 catgtccaaa gacagcttta ccaatttgag acaaaacagt gacttctttt tcaggaacga
     6361 tcccatacca atagttgata aatgtgatcc ccacgaagaa gaaacctaag atcaatgcca
     6421 tcatcgtcaa tgtagcagcg gcattttttg ctcttggctt cttaaagaat ggtacagcat
     6481 tactaatcgc ctccacccca gttaaagagg aagaaccaga agaaaatgct cgtaaaatca
     6541 aagcgataga aacacccggc acagccgctc ctggaagtgc agtagcttgc aatggcacag
     6601 cacctgtcac gatattatat aaaccaacaa cgatcagtaa cgagatcaca aggataaatg
     6661 tgtacaccgg aaataatagg aacgatgcag attccctcag cccacgaaga ttcagcatca
     6721 tcagtagcaa aacgattgtc acagaaatag cgacttgatg accgtagagt gctggcaccg
     6781 ctgatgtgat cgcttcagca cctgctgaga cagatactgc tactgtcaac atgtagtcga
     6841 tcaataaaga gccaccggaa atcaagccag cattctttcc aagattctca ctgctgacga
     6901 catatgctcc cccgccatga ggataagcat ggatgatttg acgatatgat agcgttaatg
     6961 aaatcaataa aataataaca aaagcggcaa tgggtagcga ataccagatg gctgcagcag
     7021 acaaagcgac taaaacgaca acgatttgtt ccgtaccata tgcaatagat gataacgcat
     7081 cagacgacaa taatgccaaa gcagcaaatc gggttaattt gtgctcatca ttttcagcag
     7141 attttaaagg cttacctact aacaaccttt ttaagtaatc caatttctaa actcctttac
     7201 acacaatttt acttcaagtt ttatagtcga aaatttatag taaacaagat gttatagtac
     7261 gctcactgac cttaaaagtc aataaacttt aagaaaataa ttggaaaaaa acagaaaaat
     7321 atcaagcgct ttttcaaacg ctttaataca gcaaaaatct aacatttttt tatgggcttt
     7381 ttctttgaat tctataataa aaggatagaa cttgacttag aaaatcaagt tctatccttt
     7441 ttgatatctt aacttttgga agagagatgt aaggctgctt tctacccatc attcttacta
     7501 ctcgaagcat agcgcagttg tcacaacctc ttgataaacg gtgtttaaaa gcttgcatct
     7561 gcggtaataa gctcaaccaa attaaaaaca taagaagctg tttttatttg gtcgttctta
     7621 ttacttgatg cagagcagct tttttacaac ctcttggtac acggtgttca atcagctgac
     7681 cctcggtatt agctcaaaaa aacggcaaaa tatgaggaac tatttttcca tttttttctc
     7741 taatactcag gtcaaaacac tgatttcaca acctcttttt ttaatgaaaa atatggctct
     7801 catgcgccgc ttctttgaat ttcgtcattt tttcttcgat gaacggatag attgccgttc
     7861 ctacgattcc aaagacaaca aacaaaccga tcatgatcca gattgctttc gtagcatttg
     7921 gccaataaat tcctcctgca gattcccgta acaagtttac cgcatgagta aatggcaaga
     7981 acggattgat catttggaag aatttccctg agacttggat cggatagttc ccgcctccgc
     8041 cagagatcga cagtactaag atgataatag cgatcccttt accgacatta tcgaataatg
     8101 cagccaagac atagacgatc atcatgaacg ctaaggcgat caagacagca aatgacacgc
     8161 tgtagaccgg attttggaca tctactccta gtaagaaaat attccctaat gtaacgatca
     8221 agctttgcgc aatcgccatt gtcaaaaatg tcagcatacg agcaacgaat tgttctcgtt
     8281 tcgtaaaatt gtttcggtct ttctttccta aatagtattc tgtcgtagca acacttgaaa
     8341 gaagaacagc gccgacccac agacatagtg cagtataaaa cggggtgcta gctgaaccgt
     8401 tatttgcgat tggataaagc gcattggttt gtagctcaac aggttgtgta aagaagtcac
     8461 tttcttttgt tgcgtctagt ttcaataatt tgatgacttc gcctagatcg acttcttgtt
     8521 cgccttttcg gatcgcgtct gctgcttttt ggataccagc tttgatattt ggccagtcat
     8581 tgttgatcaa gtccgcagca gcgttcacag ctgtttcgac ttctggcatt ttttcattta
     8641 ctgttgtcaa tgtaccggtg atttcatttt ttagtgctgg ccaatcattt tggataaaat
     8701 cagcggccaa tcctaatttt tgctgaatga tcggtaattc attgttgtat aggtctgccc
     8761 cttcattgat gccattgacg atggtatcca tatttccatt cagcattgta ttggcatcat
     8821 ggatttcttg tccaattgca ggcatttctt tttgatattt ttctaaaatt gccactgcat
     8881 tcgttacagt tgctttcgtt gagctgagaa gcgaatcaaa gtcgatctgg tccgctttgc
     8941 tcagtgcgcc ttgtgcagtc ccaatcgtat cgatgacttg gtctagtaga gaagtgacag
     9001 tggaactgat ttgacctgta ttgataccag caatgatgcc attgatatta ttaacaacgg
     9061 catcaatttg atctagcaat tcatcaatag ccttcgtgtc ttcattttga acagctgtgt
     9121 tcaaagcaga taggcggttt tgcagattgc ttagcaaggg ttttaattga tttagctgat
     9181 caataattgg ctgtaatttc gtatttccag cacttgtttg caatttagtc aggaactcga
     9241 ccagtttatc gattgcattt tgttgttgag atattccgtc aataaagccg ttcaatacat
     9301 tgctgatgtt tttcttttca tcatcagtca gcttaccatc ttcaatagct gttcttacag
     9361 tatctattaa cgaacctgtc gttgttgcca cttgtccaat tgacttcaat gtaacatcta
     9421 cactgtttgt gatgcttggt atcgcatctt tcagctgaga ggcacctgat tttgtttggt
     9481 ttgctagatc acttgcctga ttttctaaat ttttcacatc tggcaagata tcttgtactt
     9541 gttggatgat cgtcaagcct tgttttgctt catcgattcc ttggttcatt gtctcttgga
     9601 tcgaagcaaa atcgccgtcg atctctgcta gttgcttacc ggcattttgg atctctggga
     9661 ttttttcttg caaatcaagg atgatttttg cttgatcttt caactcaggc attttgtcat
     9721 tcaatgcaac gactttttca cccatctcat ctactttagg gatgtaatcc acgaattcat
     9781 ttgctttatt cagtttttcc ttgatttcag gtagttgact ttgtaattcg aggacttgtt
     9841 ttgtgtagcc gtcgatcgtg tccaaatttt catctgttga taaaatcata tctttaactt
     9901 tattgatact tactaggttc gtatcgatgt cgtaacctat ctcattgaat actttcaata
     9961 aagtcgaact ggctgttttg ataaattcat ttgtgatttg cgattggatc gaacttgctc
    10021 ctttatcggt gattttcggt gcaatcgcat tgattttttc atttaccgta tattcgattt
    10081 ttggtttctt gatatcacca ctagtaaaac tcagcagatc ttctgagaaa tcctttggca
    10141 agtaaatacc tgcgtaatac tttccggaac ggactccgtc ttctaattgt tcttttgaat
    10201 caacgaattg ccatcctaat tgtttatttt tatgaagcga ttcgatgact tgctccccaa
    10261 tggccacttc tttaccttga aactctgctg gcttgtctgc actgtaaaca gcaattggca
    10321 gctctccagt atttccatat ggatcccata atgctttgat gttaaaccac gcatatagcg
    10381 aagggatgat catgatcgcg atgatcagaa gtgttgcaat cgggtttttg aaaatccgtt
    10441 tccagtcaag caaatataat cgaagcgtat ttttgattga ctgcatagtt ctcccccttc
    10501 ttcttttttc agctgaatta ctttaccatg tatttcatac ttttttcaat cggctttttt
    10561 caaaaaagtc gaatttttgg acatatcacg gcaattgtct cattgtaatc tcttacatat
    10621 tgagaaataa ttaaggatta cagcctttac tttatcatga aataaaaggg aaagataatt
    10681 ttatgccaaa gtttttatct attatacgta tacgcaaaaa agctaaaaca ttttttgtct
    10741 ttgcccctac aaaaatgttt cagctttttt cgttttttat tcctgtattt cttatttttc
    10801 gaatgacagg atgattttcc cagcaggagg atgtccttca actagctgat gtgcttggat
    10861 gacatgctta agtgaagcag acagattcat tgaaataaaa acatgaaagg ctcctttttg
    10921 gtaggctttg attatgccag caaaggcttc tgcatctaga tattcctttc ttggaacaaa
    10981 cgattcataa aagccttcct ttttttgccg caaatctaga tctgggaggt catttaatgc
    11041 aacatacctg ccgcctggtt tcatgatctg gatgccggtt tctcctttga tacttccttt
    11101 cgtcgcatcg attacaaggt ctgcctgatc agcaaattgc agacctggat ttgttttatc
    11161 ataagcagca aatgctgaag ctcctaattt ttttaccttt tcctcatttt tactggatgc
    11221 actggttaag attcggattc ccttttcatg gagaagctgg atcagacttg acccgaccgc
    11281 acctgatgct cctagtatca ttacagtatc tgtcggctgg atttccgtca aatggttgat
    11341 tagattataa gccgtaattc ctggcgtgac cattccggct gcttcttccc aactcatttt
    11401 atctggaatt tttgctactt ttgctgatgg caacacgact tcttctccgt aagtcccgcc
    11461 gactgcatgg acagctactc gatcacctac atgaacagtt gtgacatctg aaccaatctc
    11521 tgtcacaata ccagcgccat cattacctgg tacataaggg aatttcaatg ttcgtatctc
    11581 tttcatttct cctaaacgca aggcaacatc ataaggattc acactgaatg cttttatttc
    11641 tacacgaaca tgtccagaac cgacttctct gggatgagca tcgatttctt caaaaacatc
    11701 ttgtgcttct ccgtaaccgt taattgcaaa tcttcgcatg gtcaccatct ccctttttct
    11761 ttaagtttac gtttatgtct ttattttgac aaaaaaaatg tcttttcgtt ttggcgcatg
    11821 attcaaaaca aaatagttgt cttttttcgc gtaacgtgtt aaattattta tctaaaagcg
    11881 taaagattac gatttacgct aataaaaaat aattggagga atttgttgat ggctaaaaaa
    11941 tcaaagattg ccaaagcaaa aaaacagcaa gaaacgattg aacgctatgc tgctttacgc
    12001 caggaattaa aagcgcaaaa agattacgaa ggcttgcgta aacttccttt agatgctcgt
    12061 ccagaacgat tgaaaaatcg tgatttaatc gatggacgcc ctcgcggata catgcgtaaa
    12121 ttcgggatgt cccgtataaa attccgtgaa ttagcacata aaggtttgat tccaggagta
    12181 aaaaaagcca gctggtaatc caagtctggc tgtaatgtaa aggaggaggg cgcatggacc
    12241 actccttgga tcatcaaaaa agatacgttc gcttcttcta gcagaaatgc tggtactaga
    12301 agcagacgta tcttttttta cgcacagctg gtcctttttt atatgtaaag gctgcatggt
    12361 tacttcgcta tatttattta gtaacaggag tcagtgcttc gatacccaca ctaattttca
    12421 atgctcggtc aacttctgcc ataatgggtc gatccaaatg gcagaccttt tctttcaatc
    12481 ttgatttatc gatcgttctg atctgctcca acaggataac ggagtctctt tctattcctg
    12541 ttccagtagc tttgatccca atgtgagtcg gaagcttagg tttagccatt tttgccgtta
    12601 tggccgcaac aatgatcgtc gggctaaaat ggttacctag attattttga ataaccaaaa
    12661 ctgggcgtgt tccgccttgc tccgatccca cgactggaga aagatcagca aaataaatat
    12721 ctcctctttt taccatagga tcctccttat tcttgatatt ctcttggtat ccgctgtcct
    12781 aatccgcaag ccacttcata gtggatcgta cctaattgat ctgctatatc ctgcatagtg
    12841 atttctttgt ctgcattttt gccgataagc gtcacttttg ttccgacagg aaattcttga
    12901 ggcaatcgga tcatcagttg atccatacat acacgcccaa tcgtttcaca gtagttccct
    12961 tctaccaata gagaaaaacc ctgcatcttt cgtggccagc catctgcata accgatcggt
    13021 atcgttccga tccactctgc ttcaggagtg atatatgttt ctccatagcc gattccttca
    13081 cctgctggga gttttttgac ttgaatcaat tcagaaacca gctcaagtgc tggctgcaat
    13141 ggataaactt ccggtagtgc gtgcccagag ggattaagtc cgtacattgc tactccataa
    13201 cgaatcatat tgccgattgt ttcatcatgc cataaagccg ttgcactatt gctgacatgt
    13261 acatatcgag gaagttcggg aagttttttc agcacttcta taaagcgttc tttttgcaga
    13321 ttccaatatg tatcatctgc ctgatctgct gtagaaaaat gggtaaataa accttcccat
    13381 tctaatacac gactttcttt gatgaatgca gctgcctctt ttacttcttc aggtgtacaa
    13441 aatccgatac gacccatccc agtgtctgct tttagatgaa tcgaaagagg cgtctctagc
    13501 ttacttttct ctaaaacagc agctgctgct tgcaaccatt cccgtgtacc tgcagttact
    13561 gataaatcat gagcaacagc tacagtcagt gcgtcgtaag gaaccatatt caagataagg
    13621 atgggctgag taaatccagc ttctctcaac tcgactcctt catctaaatt tgaaacacaa
    13681 aagcccgaag ctccacctgc aactgctgcc tcagctgttt caatagctcc atgaccgtat
    13741 ccgttcgctt ttactactgc aaacaattct tttccttgcg gaagtcttgc aacttcattt
    13801 gctacatttt cagttatagc ttttttatgt atcactgctt tcgttgggcg gtgccaagcg
    13861 acaaccatcg tttttccttc tttctagtct tccaaaataa tttgtgcaaa agctgtttca
    13921 tttgtatgag taatactgac ccatacattg ccttcatgag gtgaacgcgt cacaacaggc
    13981 tgaccatttt cattttttaa aatctcgaca tcttgaaagg taacttttcc gatcccagtt
    14041 ccccaagctt tagagaaagc ctctttgcaa gcgtaacgcc cgcctaaaaa ttctacttgg
    14101 cgatgaaaag gcaaggactg gaatagtttc atttcatcag aggtcaagat tcgtgcaatg
    14161 aattttggtt tttcttcgat cagccgagtg atcctaggaa gttcgactgc atcgatccca
    14221 attcctttta tcatatgctt ttctcttttc aataaattta gaacactctc attctaccaa
    14281 attataacca ttttgccaca aataagtcca caaataacaa aaatgaaagt ttctcttaaa
    14341 aaagagaaac tttcatttta tgtttaatcg ttatttgaac ggattacaaa tccgcgtttt
    14401 ttatcattgt gacgtttacc gccatctttt tggctgttat tatttttgct ataaccgcct
    14461 tttgatttgt ttccacgata attaccgccg tcacgacgat tacggttgtt tccgccacca
    14521 cgtttgccat ttttattgta tccttttttc tgcattggca atgggcgttc tggtgtgatc
    14581 ttcactggca ctgcatcagc tggatctttt gctgtcgttt ttagcaaaag tgcaactaaa
    14641 tcttgtgcag aatattcttc taataattta tctgctgttt gcaggtattt atctagacca
    14701 ttttctgcaa gttttgtttc gatttgttca actgcagcac ctaattgacc tttgaatgct
    14761 tctttttcgg ttggtggacg taaagtcgtc atccgttttt tcgtcaagtt ttcaatcaca
    14821 tgcaagtagt ccatttcatt tggtgtaacg aaagtcacag acataccgcc ttttccggca
    14881 cggcctgtac gtccgatacg gtgaacgtag ctttctggat cttgagggat atcatagttg
    14941 tacacatgag tgacacctga aatatctaat ccacgtgcag caacgtctgt cgctacaagg
    15001 atatctaaat gaccgctctt aaatgaacgc aatacgctca ttcgtttttg ttgagacaaa
    15061 tcgccatgga ttccttctgc acggtaaccg cgtgcttcta atccgcgtgc caattcgtct
    15121 acacggcgtt ttgtacgtcc gaagacgatt gttaattcag gtgtttgaac atcaaacaag
    15181 cgagtcatga tatcgaattt ttcgtattct tttgcgcgga catagtattg atcgatcaag
    15241 tcagctgtca tttctttcgc tttgatcttc acatgatgtg gatttttcat gaatttaacg
    15301 ccaatattct tgatagctgg cggcatcgtt gctgagaaaa gtaatgtttg tctttgatca
    15361 ggaacttgtg aaatgatttt ttcgatatct tccaagaagc ccatattcaa catttcatct
    15421 gcttcatcca aaactaatgt ttgaacggtt ccaagtttca atgtgtggcg gttaatgtgg
    15481 tcaagcatac gtcctggtgt acccacaacg atatgtggac gatctttcaa gccacggatc
    15541 tgacggccaa tatctgctcc gccgtaaacg gcttgtacac gtactttttt gtcgcgccct
    15601 aaacgatata attcttcttg tgtttggata gctaattcac gtgttggtgc gataactaaa
    15661 ccttgtaatt cgtgacgatc tggatcgatt ttttctaaca ttggtaatcc aaatgcagct
    15721 gttttccctg tacctgtctg tgcttgtcca ataacgtctt ttccagctaa tgctagtgga
    15781 atcgtttctg cttggatagg cgttgcttct tcaaaaccag cgcgttcgac tgatttcaac
    15841 aattctggtg ataattctag ttctttaaat ttcaaatgaa tcctcctata tggttgttaa
    15901 ctgaggatgt agcttttttg ctaccccgtc gatttgttcg gtcaaagtgt attgtttctt
    15961 tttgacagtg gccacgcacg tttttatcca ttcttagccc ctgtggcacc accgaaaaat
    16021 cactttgcga agtttaggca ttagaaaagc caaacgggtc gcgttcagct ttatcattat
    16081 tatgacatct ggcttcaaca agttgtttct atggcaaaac cagtccaatt tctcttcatc
    16141 tttcggcaat aggttattct aacatagttt ttcgttttct gcaagtttac agatttttat
    16201 ttcatttgct gaagttgttc taccacttca aataagccca tgctgttgct gccttttagc
    16261 ataatactat ctgttgctgc aagattttgt ttgatagcat caatcaattt attcttttct
    16321 ttttcaaaat agaacacagg tagttggggg tatttttggt tcaattcttc ttttagtgca
    16381 tgcatttgtt ccccataaag gaaaatcatg gcgaatttct caggatcgat atgttcactc
    16441 atttgcgcat gcatatttaa agactctttc cctaattcca gcatatctgc taacacagcg
    16501 attctgcgtc cttttgttgg cagattttta aaagtatcta ataccagtcc catggctgtt
    16561 ggatttgcat tgtagacatc gctcaaaata gctgcaccat ttcctgccgt tagccattcg
    16621 gttctgtttt gagtgataga aacatgggcg agcccttggc gtatctcagg tatggacagt
    16681 ccaaagaagc gcccgatcgt atacgcaatc aaagcattcg ttacattata acttccaggc
    16741 agcgggatcg taaatgtttc tccttctact acaaaatcgg tttgtgcttt tccttttgct
    16801 gtcacttccg catgaacatc gccatttcca ataccgaatg ttgtgactgt ttgtactaat
    16861 gttgccgtta aaggtgtcag caacggttca tctgcgggca caacgagtaa tccgtctgat
    16921 acaagtccgt cagtgatttc cattttggct ttagcgattc cttctcgcga cccaagattt
    16981 tctatgtgtg cttcaccgat cattgtgatt gctgcagctt ttggttgagc cataagtgaa
    17041 agttccgtga tttcattggc gtgatccatg cccatttcca aaacgatctt ttctgtatct
    17101 tggggcatgt gcaaaatcgt gtaaggaaga ccaatattat tgttgtaatt tccttgcgtc
    17161 ttatatgttt tgtatttttc agacaagaca gacgcggtta gatctttcgt ggtggtttta
    17221 ccattgcttc ctgtaattgc aacgacttct gcgcctactt tttccaagta ataggttgcc
    17281 aattgctgca tggctttcaa aggatctgct acaggaataa ctggaaaatt ttttggagct
    17341 tgttcaacag gcaagctcca aaatgaagca gatgctccgt ttgtgatcgc ttgctggata
    17401 aattcatgtc catctcgcgt accagcaaga ggaacgaata aacttccttc ggttatcttc
    17461 cggctgtcaa attcgacatt ggtaatcttt gtcagtgcag agcattcgct gcccacggct
    17521 tgtgcaattt cttgtattgt tagattcatt gagatctctc ctaaaaaagg ttgtgaaaaa
    17581 agcgtttggc ctaaacggcg ggttcgcatg actctcactt ccaagtaaat ttctctattc
    17641 gtatttagaa gctagaatga acgcggttac gcaatcactc cagcctcttc tttatttctc
    17701 tttattcatt tttttcaaaa aaagattgac gctgatggta tcgattcatt cctaactgga
    17761 tcagttcttc aatcaaatca ccgtatttca agcccatatt ttcccataag agtgggtaca
    17821 tactgaactc cgtaaatcct ggcatagagt ttaattcatt caggaataat tcatttttat
    17881 ttgtcaaaaa gaaatcgcac cggctcaatc cgcttccacc taacatcgtg taagctaact
    17941 tcgcgtactc ttgcgctttt tgataaactt cttctggcac ttcggctgga atctgcattt
    18001 cgattttatt attgatatat tttgcttcat aatcatagaa tgctacgtct tttacgactt
    18061 caccaggcaa agtcgtccga acgtcttcat ttcctaatac agcaacttcg atttcgcgcg
    18121 cttcaattcc ttgttcaacg attgctcgag aatcatactg ataggctgtt gctaaagcat
    18181 tttgcagctc ttctcggttt tctgcttttg taatgccgac actagaaccc atattcgccg
    18241 gtttgacaaa catcggataa agcaaagaac cttcacattg atcaaatact tttttaggat
    18301 tttctttcca ttgattctta agtactggta cataaggaac ttgcggcaca ccagcagctt
    18361 gtaaaatata cttggtcatg attttatcca tggcacatgc actggtcaat acgcctgcgc
    18421 cgacataagg catattcaat gtctctaaga agccttggat cgttccatct tccccgtttg
    18481 gcccatgtaa aactggaaaa acgatggctc cttcttcttt gatttcgccc ggattgatca
    18541 cttttcctgt aaagccttcc tctgtctgtc cacttgggtc ccatgaaaga tgcaagacat
    18601 ctttgctggc aggtttttct gttagtaatg gacctttgac ccattgtcct tcttttgtaa
    18661 taaatacgag ttgaacttgg taataattat aataaatggc atttaaaact gaaaatgcgg
    18721 aaagaatgga cacttcatgc tctgcgctgc gtccgccata tagtaaagta atcttcaaaa
    18781 gattgtcctc ctgtattcta aatcgttcag tgatttactc tcatatttta gcacaaaaca
    18841 aaaataaacg aataacttat ttataaaaaa acgagccagc ttctaaaaga acgagcgtca
    18901 tttatttttt gtcagctaga ttatttgtcc cgttttttat aaaaagttat gataaagaaa
    18961 aggagggatg atgatggcgc aaacaaatcc acgcagccgc ttggcagaaa tcattcgagt
    19021 gttcatcaat tacaatgtag tgccaaactt tgtacagcaa aaaaatcccg aacaggtaaa
    19081 aaaagccttt gaagaactag gccccacctt catcaagata ggacagatgc tttctgttcg
    19141 agaagatttg ctttcttctg ccttcactca aacattcaaa acattacaag atagtgtacc
    19201 tagcgacaca ttttcaacgg tcaaaaagac gatcgaaaca gaactttctc tttcattatc
    19261 agatatattc gatgattttt caaaatcgcc ttttgcctct gcttctatgg ggcaggctca
    19321 tcgtgccaag ctgaagaacg gtgacgcggt agtcgttaag atccaacacc ctaacatcgc
    19381 cgaagagatc cgacttgatc ttcaactatt tgaacgagcg atccctttga tcaaatacat
    19441 tcctgaaact agcgtagttg atctaaaagg ggtactccaa gaagtaaaac gttccttgat
    19501 caatgaaatg gacttcttaa aagaaagtca aaatggcgaa caattctatc aaaagaacaa
    19561 tggctggaaa gagatccgca gccccaagat ttatgacgct ttttgttcga aaaaagtgat
    19621 cgtgatggaa gaaatgtctg gtaaaaactt gaatcattta atgaacgccg aaaacaaaac
    19681 tgaaactttt atcactggaa ttcaaaacaa gcagctgaaa caagaagttg caaagctttt
    19741 agttgagaac tttatgaaac aggtgtttga tgatggtttt ttccatgctg atcctcatcc
    19801 agggaatctg ctattccatg tactaacaaa agaagaacag acacaagcta gccgaaaaac
    19861 tgaaacagtc catgaaaaag agttcggttc ctttgctttt cgagcctcca cttctgcaga
    19921 agaccctgtt gcgccatata ccatcaacta catcgatttt ggtatgatgg ggcatctttc
    19981 tgcaggactt aggcaaaaac tcacacaagc cgttttagcg ctgtatacga aagatgctta
    20041 tcgaatcgaa aaagcggtcc ttcgactttg tcagcaagaa ggctcgtttg atgaaagtcg
    20101 gttccaccaa gaactgacaa gttttcttga acagtattat gattctccta ttgatgaaat
    20161 caacttgcaa gaagtattca cacatgtcgt gacgatttgt catcaaaata atctgcagtt
    20221 cgatcgtgat atcacgcttt tgctgaaagc atttgggaca ttagaagggg tgatccgcgt
    20281 cctcgatcct gaagtttccc tcatggaagt cgcttcgcct tttgctcaac attattttct
    20341 cactcatctg gatgtagaag atacattgaa acaaagcgga ttagacttat tggaagggat
    20401 gaaggctgcg cctaagatcc ctcaacagct ccaccatcta ttagaaatgt ggacttcggg
    20461 acaaggaaaa gtcaatttgg aattgaaaaa gcaagacaaa ttattgagca ggatcgaaag
    20521 tatgatcaat cggcttgttt tcggtatgat tttagctgca ttgatcgtag ggtcctccct
    20581 gcttgtccaa gcagcacctg tagaaaacgc agaggtcgtt tccttattag ggatatttac
    20641 gtatgctatt gccgcattcg tcattatttt tttggcaatc gatgcattga tccaaatgta
    20701 taagaagagg aaaaagtaga aaaaggttgt gacagaaaga atcagcttca agaaataaga
    20761 aggggtttta cataaattgt ttctcaaatt tttgtgaaaa ttcggcttat ttttcgaaga
    20821 ggctacttct gaaacaccga gaataaaaaa tgtgaaaaag ctgttctgca cccagtaata
    20881 agaacaatca aaaagggaac atggaacaca tttatcctgt ttccctgttc cctttttgat
    20941 gtattcgagc ataaataaaa taccttcgtt acctactatc ttctgtactt ggtaaacctt
    21001 agtcaattgc cttttttaac gcttgacgaa aagacatatg atctttctcc gtaaagggtt
    21061 ttggaccctt tgtccttatg ccagcttttc ttaactttcc actatgataa cgttgttcta
    21121 gaagcgtgcc gatattcgct tcgtcaaatt cttttccaga gtgatggaac actcgcacac
    21181 ccttcggcaa tacaagtgaa gctaaaccat aatcttgcgt gatcaaaaag tcattcttct
    21241 taaccatacc gacgatttta taatccgcac tatcagctcc gcggtctacg tagacgattt
    21301 ggacatgatt agcgtattct ttggtcgtat aatggtccac actggtcacg ataaccacgt
    21361 caagaccata ggattctcct aattttatga catcttcttt tactggagaa ccatctccat
    21421 caatgaatag cctcattctt tttcgccttc ttccataaat gataaacagt tactaatccg
    21481 ctcagtaaaa gaccaacatt gatccatttt gccaagataa gcagttgtac actttctatc
    21541 ggcactgatt catggttcag cgtgatcaat aatagatgga ttggctctcc catttctttt
    21601 gctaaaacaa acaaaagcgt catcaataaa aactggtgga tcacactccc tttattttga
    21661 gtagtatact tgacaacgat ccggcgatcc attggaatag ctgtatcagt ttgataatat
    21721 tccttattta gccagctgcc tgttactacg tgccagaaac taagcagaaa gacacctatc
    21781 gcaaaaccat ttggaatcaa gaggaccaat aaagaagaac tcagtccaag caattgcata
    21841 gccaatggag accatgttaa acgtttcaaa atccatggtc cgactatttt tgctgcaatc
    21901 aagcctgctg cataaggcaa atacataaaa atcgaaagtt tttctaatcc gtacagtatg
    21961 ccaacataaa aactgctaaa taaaaaaagg aaattcccta gcattccatt tagaaaagta
    22021 aacagattta gccagcttgg caacttccat tccttcttct ggtgtcctaa aacaaacacg
    22081 aacaagatga acagcagcaa gaaaccataa atagcaagat caaaaagcct ttcatcgaat
    22141 aacaatcggg catttctcaa aagaaacaat aagccaaaga atatcaaaaa taaaacaagc
    22201 tctcgcgtag ctaccagatt tcttttgatg tctttgaaat ccagttcgta acgcggataa
    22261 tgactaaccg tatggtaggc catgacgtaa aaaagtgtat aaatagtaaa gcttgctgca
    22321 atctgagtcg gtgcaggcaa ctcaatcgct tgatacagga gaaatagcca gatagctgca
    22381 aataagtact ttttcccatc catattgata aaaccttgcg tcttttcgtg aaaattgacc
    22441 gtggtattag caggtacaag ccatgctgca ctcagcccta gcaaaacact tgaaaaataa
    22501 aataaaggaa aataaaatac gcctaatatt ccaagcaatg aaccagcacc accaatcagc
    22561 agagcgatca tcagcaacgt gtaactatct agaccaaatc gtagactgtt gactaaaaat
    22621 agtccagtca tccgaaaggc ataaaacagc gtaaatggca aaatcgtcag ccaattatgc
    22681 gagtctgtta gtcccaaaaa taaaagataa ggaataaaaa taaccgtgtt acttaagata
    22741 aagggcgttg tttgtgtaaa attacgccca aatcgtttga gtttttcgaa catgacaatg
    22801 gctccttaaa cagtcttata actaatctgc tcttcgattt tagcattaaa ggggaaataa
    22861 accaatttta cagaatatat tcttgtaaaa aaaaatacag aaagaagcat aagcttcttt
    22921 ctgcattttt acggtacttg attactcaag cagacaagcc cttctccaca aaagtcttgc
    22981 ccgacacccc tgcatccggc aggtgataaa gatagaaatc aattatcctg tgcctccaaa
    23041 atcaattagg agctctgtaa accagagtcc ttctcgaccc gtcgcataaa tttactttaa
    23101 cacagttcct atgtttatgc gagagctttt ttcattttat aatcgaccat ttgaaatcct
    23161 tgaccgatat ctgaaataag ttcttctgta atctcaaatc cttcatgctt ataaacctcg
    23221 attgcttgat gattcccctg attcactcgc aaaaagatct ctctttcctt tgtttgcgca
    23281 gcaagttctt cataccagcg aaaaactgaa gaagtcaatc cttgaccacg tactttattt
    23341 agcaaatata atttacttaa ataaattttt ccatttatct cttcataagc agtgtaaccg
    23401 acagtctttt cttcgctttt taataaaaag taggacacac cttctgtcag ttctttttga
    23461 atctgttttt ttgactgata agttttcagc atgtaatcca cttgtttttg accaatgatc
    23521 ggcacaaaag cttccggcca tacttcttgt atgactgcca tcagctcatc cagttcattt
    23581 tctgttactt ttattttttc catacaccca cgtccttttt tacattataa atgaccttgc
    23641 gcttgatgga ataaaaagag catgatcatg ctatacacac ccaccgacca tggtttcaag
    23701 aaaatcacaa tctgcataaa ttccctaaaa gataatttcg tcaaaccagc tactagacag
    23761 atcaagtcgt ctggcgcaaa gggaagcagc aaggtaacaa ctagtacttt tttaatatct
    23821 ttcgtttttc ttgtcagcaa ttcatcaaat ttctgatact tttttggcga taaaataagc
    23881 tggacaaagg ctacgccata gtaacggaca agcaaaaatc cgattgcttc cccaatcact
    23941 aggccaatac aactatataa aagcccaaat ccattgccaa acatcagcat gcccgctact
    24001 gaggagatcc ctcccggcaa aataggaatg atcacttgga tcacttgcaa cagaacaaat
    24061 atcatcactg catacttgcc aaattgctgg ataaacgctt gcaaagacgt gctcgatcga
    24121 aaaatcccat gatgataagc ataaagaatc aacacaaaga aaaaaaacag accaataatg
    24181 ggcatgatct gaagacattt ttgtaaaact gatccttttt tagacatcta tattccccac
    24241 atcttttttc atttattaaa actgcctcct
//
LOCUS       DACGMI010000044        23827 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.045, whole genome shotgun sequence.
ACCESSION   DACGMI010000044 DACGMI010000000
VERSION     DACGMI010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.045"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(55..789)
                     /locus_tag="IXT46_001971"
     CDS             complement(55..789)
                     /locus_tag="IXT46_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAQ4947874.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1116..1526
                     /locus_tag="IXT46_001972"
     CDS             1116..1526
                     /locus_tag="IXT46_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAQ4947875.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1519..2220
                     /locus_tag="IXT46_001973"
     CDS             1519..2220
                     /locus_tag="IXT46_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAQ4947876.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2220..3806
                     /locus_tag="IXT46_001974"
     CDS             2220..3806
                     /locus_tag="IXT46_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4947877.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3825..4046
                     /locus_tag="IXT46_001975"
     CDS             3825..4046
                     /locus_tag="IXT46_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAQ4947878.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4043..4804
                     /locus_tag="IXT46_001976"
     CDS             4043..4804
                     /locus_tag="IXT46_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAQ4947879.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5184..5693
                     /locus_tag="IXT46_001977"
     CDS             5184..5693
                     /locus_tag="IXT46_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAQ4947880.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5768..6307)
                     /locus_tag="IXT46_001978"
     CDS             complement(5768..6307)
                     /locus_tag="IXT46_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAQ4947881.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="IXT46_001979"
     CDS             complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="IXT46_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAQ4947882.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7374..8171
                     /locus_tag="IXT46_001980"
     CDS             7374..8171
                     /locus_tag="IXT46_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAQ4947883.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            8199..8834
                     /locus_tag="IXT46_001981"
     CDS             8199..8834
                     /locus_tag="IXT46_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAQ4947884.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8854..9627
                     /locus_tag="IXT46_001982"
     CDS             8854..9627
                     /locus_tag="IXT46_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4947885.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10035..10832
                     /locus_tag="IXT46_001983"
     CDS             10035..10832
                     /locus_tag="IXT46_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAQ4947886.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10810..11223
                     /locus_tag="IXT46_001984"
     CDS             10810..11223
                     /locus_tag="IXT46_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947887.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11207..13852
                     /gene="mutS"
                     /locus_tag="IXT46_001985"
     CDS             11207..13852
                     /gene="mutS"
                     /locus_tag="IXT46_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAQ4947888.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13870..15978
                     /gene="mutL"
                     /locus_tag="IXT46_001986"
     CDS             13870..15978
                     /gene="mutL"
                     /locus_tag="IXT46_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAQ4947889.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            16000..16560
                     /locus_tag="IXT46_001987"
     CDS             16000..16560
                     /locus_tag="IXT46_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAQ4947890.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16645..18633)
                     /gene="treP"
                     /locus_tag="IXT46_001988"
     CDS             complement(16645..18633)
                     /gene="treP"
                     /locus_tag="IXT46_001988"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAQ4947891.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18856..19569
                     /gene="treR"
                     /locus_tag="IXT46_001989"
     CDS             18856..19569
                     /gene="treR"
                     /locus_tag="IXT46_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAQ4947892.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEELTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19646..20092
                     /gene="msrB"
                     /locus_tag="IXT46_001990"
     CDS             19646..20092
                     /gene="msrB"
                     /locus_tag="IXT46_001990"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAQ4947893.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20262..20864
                     /gene="ruvA"
                     /locus_tag="IXT46_001991"
     CDS             20262..20864
                     /gene="ruvA"
                     /locus_tag="IXT46_001991"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAQ4947894.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20877..21878
                     /gene="ruvB"
                     /locus_tag="IXT46_001992"
     CDS             20877..21878
                     /gene="ruvB"
                     /locus_tag="IXT46_001992"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAQ4947895.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21907..22485
                     /locus_tag="IXT46_001993"
     CDS             21907..22485
                     /locus_tag="IXT46_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAQ4947896.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22537..23019
                     /locus_tag="IXT46_001994"
     CDS             22537..23019
                     /locus_tag="IXT46_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAQ4947897.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23136..23510
                     /locus_tag="IXT46_001995"
     CDS             23136..23510
                     /locus_tag="IXT46_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947898.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7782 a         4287 c         5114 g         6644 t
ORIGIN      
        1 ataaaaaaac ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc
       61 cataaataat aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac
      121 tggtacccat gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg
      181 tacaagacgt ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag
      241 tgaagcaact aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc
      301 ttggaagaat ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa
      361 gaattcattg acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc
      421 taacacatgg tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat
      481 caattgtcca atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca
      541 agggaataga ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct
      601 gattccacca aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag
      661 catccagtca ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt
      721 acctagaacg attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga
      781 gtaatccata aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg
      841 aaaagcatcg gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat
      901 aaaaaaatga attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt
      961 taaaagttct ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt
     1021 tttctcaaaa attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta
     1081 gtaaaatgaa agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca
     1141 ttattatttt cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc
     1201 ctggaagtat cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc
     1261 ctgaaaaaat cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc
     1321 ctgctggtgt aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac
     1381 tgggagcagt cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag
     1441 gtgtagaagc tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg
     1501 aaatggagga gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg
     1561 actttaggag tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg
     1621 aatcctctcg tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc
     1681 tataaagact ataatatcgg gggcaatttt ttgactatgc tgattactcc tgcgacagtg
     1741 gcacttgcca tccctcttta taaaaacttc cgtttactga aagagaattt ttatcctgta
     1801 atggctgcga ttttagcagg aatagtcgca aattgcttgg ttagtgtagg gttcggttac
     1861 ttcttctctc ttcataaaga gatggtgatc tcattactac ctaaatctgt aacgacggct
     1921 atttctgtcg atttatctca tacgatgggc ggggtgaatg ccgtgacact tgctattgtt
     1981 gtctctacag gtatttttgg ttcgctgatc gccactcata ttttccgcct attcaagatc
     2041 gaaagtccag ttgctcgcgg tgtggcgtta ggaagtactt ctcatgctat tggtacagca
     2101 aaagcaatcg agattggtga aatagaagga atcatttccg gacttgcgat atgcgtcaac
     2161 ggaatattga ccgttttatt gctaccgtta ttctttcagc cttttgctgg cttgttttga
     2221 tgcgaaaacc actattttat gctacaataa ccaaaacgtt cgagcataaa aaaggaggga
     2281 aagacgtgta tttgtcttcc gagtatctta aacaatttga taaagatcta tattataaga
     2341 ttctcctcct agaaagtttt gaggatcaag cttggcatac cgctgcacaa ttagcgcaag
     2401 ttgttcagct ggatgcccgc agcgtgtcga aatacctgaa cgagctgtct aaaaactatc
     2461 agcagtttag cggtaagaca caccctttgt ttacaaaaaa tcaccgttct ggttataact
     2521 tttatgatac gctcgattca attgaacatg agcgtttttt gatctatctc gtgcaaagta
     2581 cgctgaaatt ccagttgctg cacgacattt tttttgaaga attccataca atgtaccaat
     2641 ttgcgcaaaa gcattacatt agtgaatcta ctgctcatcg aaaaatcaat gaatggaaac
     2701 agcaactgca aacttacgga attcggctgc aacgaggtac atatatcgct caaggcgaag
     2761 aagaaatcat tcgactttac ttgcatatga cattctggca gttgtttcga gggaaaatct
     2821 ggccatttga aacgatttct caaatggacg taaagaatat ggcagaacat atcatggctt
     2881 tttttaatgt tcgtctgaac gagatcaaaa aaagacgatt ggaatatatg ctaggtgcct
     2941 tttttttaag aaaatcacag aagcattatg ttgtattgaa tgagaaaaaa agacggctga
     3001 tttctgacaa tctgttgttc cagcgatttt gccaggtcat ggagccggta tttcctaatt
     3061 attttcaagt agaagacgag ttaggcgcat tatttcttgt actgatgact cgtgaagaat
     3121 attatagtga tcctaagata cggaagaaaa tttttgattt tcatcaacaa gcaaaaacac
     3181 cgccctttac agccctttca gaagcaaaag ccgctctttc tctttatcag gaagagcagg
     3241 ggctgccagc agaaaatcta accttcgagg cagaaaacta tttattcagc agtcattttt
     3301 tcgcctatct ttttcctaat gcgaaagaaa cgattgatgg caatagtagt gattttatta
     3361 atcatttagt tattgaaaac aaggaattga aacaatggct cgtacatttt tttgaaagta
     3421 gacacaaaca tcccaatcat ctggcattta aaaatcatgc gtttttgatg gggcggtatc
     3481 tgactgtgtt taaaacatta ggagccttta ctccacagct tccaaagatc acgatccttt
     3541 taatgacaga tttcccatta tttgaagagc aactgttaga ggagggatta cggacatttt
     3601 tccgtaatga gtatcagctg atttttctgc caacagatta tcgggggaga gaagttgatc
     3661 ttctgatttc gacaagtaaa gtccaccgca aaccatgggc ggatcttgac tattttattg
     3721 tgactgaaga actaaaatta attgattaca tccaactatc tcaaaaattt gaaatgattc
     3781 aaaaacaaaa actattaaaa caataacaaa gaaggagaaa aaagatgaca tttgaagaaa
     3841 ttttaccaga attgaaaaaa ggtgcaaaga ttattcgtaa aggatggagt ggatttgaac
     3901 tttatgttgt tctcgtatcc gatgatgaat ttgatggctg tccggtgacg ccgtacttat
     3961 tgatcaaaac aagtgacgaa ggtttttcca gcttcgctcc tacagtttgt gatattttag
     4021 cagatgattg ggcgatcgta gaatgaaaaa ccagtatcca gatctagcta aacaggttgt
     4081 atttatcaca ggagctgctt ctggaattgg tgctgcgcaa gcccgagcgt ttcttgaaca
     4141 agatgctttt gtatttggat tagatcaaaa gttcggtaaa atggaagaaa tttctttgcg
     4201 atttcctgaa acttttgcct acgcactagg tgatgttcga caaatgaaag aactccaaca
     4261 agcggtatcg aaatgccaaa atcattttgg tgaagttacg attttactga atacagcggg
     4321 gatattggat gcctacaaac ccttgatgga aactgacgaa tcgctgtggg atctgattta
     4381 tgagacgaat gtgaaaagca tgtatcagct gacaaaaatc atccttcctg atatgatccg
     4441 ccaaaaaagc ggaacgatca tcaatatggc ttcgattgct ggcttgattg ctggtggagg
     4501 tgggatcgct tatacaagcg cgaaacatgc gattgtcgga tttaccaaac aactcgctct
     4561 ggattacgca ggacagggta tccgagtaaa aggaattgct ccaggagcca tccaaacacc
     4621 aatgaatgcg gctgattttg aagggaaagg tgagatggca gagtgggtgg caaatgaaac
     4681 accagtcaag cgatgggcac agccggaaga agtagctgag ctgacgttat ttcttgcctc
     4741 tcctcaagca agctacatac aaggaacgat catcccaatc gacggcggat ggttgttaaa
     4801 ataaccttgt gtttttttca agcttctgta tgataaaact aaagagagaa acaacggttg
     4861 atgataaaaa aagtcgatga ctgttcccga cattcgatgc cgaacagcca gttcaaaaaa
     4921 ttctttttaa taatcgttaa tattcgaaac taagcggctt ttcacgacct cttgatataa
     4981 acgatattca aaagcttgca actgcggtaa caagtccagc caaatgaaaa atataaggag
     5041 ctatttttat ttgaccattc ttattacttg ttgcagggca gctttttcac taccttctgc
     5101 gacacttcag ttggaatttt cttcccatcc tttggtcgcg gtcattacca agataaaatt
     5161 atcttgcaaa ggagaaatag aacatggaaa aaaataatac ccgttcagcc aaacgctgga
     5221 caacgacaga tgtgactcgg atggcgctag tcactggttt atatgtggca gtgacgctgg
     5281 ttttgtctgt ctttagcttt ggagtgattc agattcgtct ctcggagatg ttcaactatc
     5341 tgtccttgta taacaaaaga tacatcgtcg cggtaacagc gggagtagct ttggctaata
     5401 ttgcttctcc tcttggactg atagatgttg cagtaggaag cgtcagcacg ctgcttgtat
     5461 tgcttatcaa ctataaaatc actagtcgca tcaaaaacat gaaaatcaaa atggccgtga
     5521 cagcatgcgt atttgctttt tccatgttta cagtagctgg tcagctaacg attttatatc
     5581 aactaccttt tttcttgaat tggtgggtga ttgctttagg agaattggca tcaatgattg
     5641 tcggtgggat aattatttat tggatcggta aaaaagtgga tttgtcaaaa taaagatctg
     5701 tttaatttaa aatagggcag catggaagag actgaatgtt gagtcttctt ccatgctgct
     5761 tttttgatta atttgtatga agaaatcgat ttagccgttt tttcatcaag ataccgatat
     5821 aagctgctcc agttgccttg attgcttccg gcagtaaaaa cggcagtagt ccactggcaa
     5881 atgcagttgt aaaagtaaga tcaccactta ttttcagcca gatcgttccg cagatcaatg
     5941 cagcaagaga gcccattaga ttggcaaaga ttgcatataa gtaatgagca tccgttcttt
     6001 cgatcatcca accagttatc cacgtttgta agagaaatcc aatcaaatat ccgccagttg
     6061 gcccaaataa aacagctata cctccagtca tccctgaaaa tacaggaaga ccaatcaagc
     6121 caagtaaaag ataaactcca acagatatca atcctagttt tcttccgaga aaagttgctg
     6181 ttaatccaat agcaaatgtt tgccctgtca aaggaaccaa accaaaagga atggtcatct
     6241 gagaaaggac agaaataatc gcggcaaatt ccgcagcaag tatcaattct ttcaatgttc
     6301 ggttcataac gccctctttt cgttaactta atatttttat ttggttaacg aaattgtaaa
     6361 acaaagtgat tactttgtaa atagaaaata taaaaaaaga ccagctatcc aatagatagc
     6421 ggtctttttc aagaaagctt ttgaaattat aagctttggt tgtagtattc aacgacaaga
     6481 gcttcgtcga tttctggata tagttcgtca cgttctggta aacgagtcaa tgaaccttcc
     6541 aatttttcag cgtcaaagct tacgaatgct gggcgtccaa cagttgcttc tacagcttct
     6601 tttactgtta cgatgttttg tgatttttca cgaactgaga tcacttgacc cacttctacg
     6661 tggtatgaag ggatatcaac gcgtttgcca tcaactaaaa tgtgaccatg gttaactaat
     6721 tgacgtgctt gacgacgagt cgttgcaagt cctaaacggt aaacaacatt gtctaaacgt
     6781 tgttctagta agatcatgaa gttaacacca tgtttacctt ctttgatttt gctagctttt
     6841 acgaacaagt tacggaattg acgttcgttc attccgtaca tgtgacgaag tttttgtttt
     6901 tcagttaatt gcatgccgta ttctgattgt ttgccacggc tattaggtcc atgttgacct
     6961 ggtgcgtaag ggcgacgtgc taattctttt cctgtgcctg acaatgagat gcctaagcga
     7021 cgagaaattt tccatgatgg tcctgtataa cgagacatta aaatttcctc caatgaatat
     7081 aagtttttgg agtaaaataa tccgttgaaa aattcataat catatagttt gttcttcaat
     7141 cttcaccttt gcagccgcgg ttacacaatc gaacccgaga cggggcaaca aactagggat
     7201 gagttattat ttttctgctg cattatttta cacaaattac agtatatgat agatcatcca
     7261 cgaatgtcaa gataattagt acataaaaac gctttacaaa cctaggctgt ctttataaaa
     7321 tgagagggta tgtgcaaatg gaaaaaagcg aaggaagttt aaggagaaaa tcaatgaatc
     7381 cggtatcacc attatttgag aaaatcgatg cttcaattga aaagaaggcg aatctttttg
     7441 aaaacagctt ttcacgttac gctgttcgag cggttctcgc ctgtttgttt ttgactttag
     7501 gaacggctgt ggcatttgcg atcgcgatga agggggaaga tatcgcgcat ggtctaggaa
     7561 agattttata cgcatttatg ttcagctggg gtctggtcat gattctatac atgaacgccg
     7621 aattaggaac atcgaatatg ctttatatga ccgtgggtgt ttttcggcag agacttgctt
     7681 taagtaaggc agccaagatt ctatttgcct gtattttttt caatatgatt ggcggtatat
     7741 tatgtggatt tctaatttct atgactacgc catttcaaga tttaacgttg gacaacttta
     7801 tgttagaatc aatagcagta aaactagcaa aaccttcagc aacgattttg gtggaaggga
     7861 tgtttgcgaa tatcgttgtc aataccgctg tactgatcag catgcggatg aaagaggatg
     7921 tcggaaaagt gatcacagtc gtattcatca ttttcatttt tgctttttta ggatatgaac
     7981 acgtgatagc gaattttcct gcctttacgc ttacttactt tgcttctcac ggacagatgg
     8041 atggaatgac agtcagcaat gtgttacata atttgttttt tgctttggca ggaaattata
     8101 ttggtggcgg tttagtaatg ggactgggat atgcttggct gaatcagtca aaatcatcct
     8161 atgtggacta aaaagtcgtt cattaaaggg gaagtgccat ggaagtttta gtttttccaa
     8221 aaaatgagga aaaagcgtta caaatggaaa agtacatgaa aaatcttttt tcctttgctg
     8281 gagtacctaa gccggaacgc gctcttttac aacaaccgtt actggatgag agcaaaaatt
     8341 tatctatttc tgaagtttta gcttttgttc attattatta tgaacaaatc gaaagagagt
     8401 atcagtatgt agcgatcgat ttagtccaga aaaacatcaa acggcttaca tttgaagact
     8461 tagtcgtatt gttgccacta gttcagaaaa aagaatggtg ggacagcatc gactcttgga
     8521 gaaaagtata cagcacatgg tgtaaagcct acccagagca gcgtgaagaa gtctttcaat
     8581 tgtttgaaaa aaaggaagat ttttggctac gtcgaatagc aatcacgttg caattaggtt
     8641 ataaacagca aacagacaca ggactattga tccgagcaat agacgaagat cgtcaaacaa
     8701 aggaattctt tatccaaaaa gcaattggtt gggcattacg cgattatagt aagaccgatg
     8761 ccgattgggt aaaaagacag ctgacaacag atttgagtaa gttagctgtt cgagaggcaa
     8821 gtaagtattt ataagaaagc gagacgacaa gagatgagac gcaaattatt tgcttttgat
     8881 attgatggaa cgttgttaga ttcaaacaaa caagctttag atagcacaag agaagcattg
     8941 gaaaaattac gcaaagccgg tcatctggtc acgattgcta cagggcggag ccgatttcat
     9001 gcgcaagaga tcattcgcga tcttgatttt acgaactaca ttttatgtaa tggagcggcc
     9061 ggttttttag accatgaaca agtatataag aatttactag atcgcgacca gttggatgcg
     9121 ttcgttcaag aagcgcatca tgagcagatc gatacagctt ttgtcagctt agacaatatc
     9181 aagcgttctt cttccaatga tgtaacggtg atggaagaag cgatgcattc tttcggtgct
     9241 gtcttgcctg aattagatca gttttttgca gaggaacaag aaatatacca agcgttagca
     9301 tttttcgatc aaacatatga tgggaagttc tcttcatatg ataaaattcg atttgtccgc
     9361 tggcatgaga acagtgtaga tgtcgtacct aaaaatggtt ctaaagcagc gacaattctg
     9421 cacttagcag aacaagtagg catccctcat gaagacatca tcagctttgg cgatggacaa
     9481 aacgaccgtg aaatgttgcg catgtcagga attgggatag ctatggggaa tgctgtgcca
     9541 gaagtacaag cagaagctaa gatggtcact gatacaaacg atcaggatgg aatttggaag
     9601 gcattgaaag agttaagcgt gatttaaaag aggttgtgaa aaagctgttc tgcatcaagt
     9661 aataagccca gccaaacaaa aatagctcct cctatttttc gtttttctgg gcttattacc
     9721 gcagatgcaa gctttcgaac accgtttaag gaagaggtcg tgacagaagt ggtcagtttc
     9781 aagaaataag aagggattta cgaaaattgc ttctcaaatt tttgtaaaat tacggcttat
     9841 ttctgaagaa gtagatgaaa caacgtttat tcgggaaatg ggactgtgac aagatgtttg
     9901 tcatagtccc atttttttat tttatttttc aaaactaaga aataccagga aagagttcct
     9961 tttgtttgac cttttctttc ttattgaaaa caactataat atagagtgat gttaaaagag
    10021 aagaggaatt tagtgtgcgg gtattgttta ttggtgatgt agtaggttca atgggacgag
    10081 agatgattac tgaatatctt cctagattga agaagaagta ccgtccgcaa gtaacgattg
    10141 taaatggtga gaatgccgct tctggacgtg gaatcacaga aaaaatctat aaaaaatttt
    10201 tgcaagacgg cgtagatgtc gtgacgatgg ggaatcatac gtgggacaac cgcggaatct
    10261 ttgagtttgt aaatgaagct aaaaagatgg ttcgtccggc aaattttccg gaagggacgc
    10321 ctggacaagg gatggtcttt gtcaaagtga accaagtcga actggcagtg atcaacatgc
    10381 aggctcgttc ttttatggtg gacttggatg atccttttcg taaaatgaat gagctggtag
    10441 aagaagccag aaaacgtacg ccgatcattt ttgtagattt tcatggagaa acaacaagtg
    10501 aaaaacaagc aatgggctgg tttttagatg ggaaagtttc agcagtggtc ggtacacata
    10561 cacacgttca gacaaatgat gcgcgaattt tgccaagagg aacagcgtat ctgacagacg
    10621 ttgggatgac aggtccctat gatggtattt tgggtatgcg cagagaacct gtaatcgaaa
    10681 agtttctgac tgcattacca aaacgttttg aagttgtgga acaaggccga tcgattttaa
    10741 gcggctgtat cttggaattg gatgatacga caggtcatgc aaaagaaatc cagctgattc
    10801 agatcaacga tgatcgaccg ttcatggagt agaaagagag gcagtttttt gcagcaggag
    10861 ccggaaattc aaaaagaagt aaggaaactg acaaaacttt taagagagaa tgaaacgatc
    10921 attcgctaca aagaacttga agaaaagatc cagcaaaacc agtatttagc tgagttgaga
    10981 gaaaaaatca aacaagcgca aaaagatgct gttcattttg cccactatga caaaccagca
    11041 gcagaaaaag aagcaatcaa acaagcggat caattcatgc aagaatttga tcagcatccg
    11101 cttgttgtag cttatagaaa acagctgttg gaagcagatg atctgcttca tcatttaaca
    11161 actatgatac aagaagaaat caatggacaa atagaggagg aaaaacatgc ctcaaaaaac
    11221 taaaaatact cctatgatgg aacaatatct aagcatcaag gcccaatacc aagatgcttt
    11281 tttgttctat cgtttaggag acttttatga actattttac gaagatgcga tcaaagcgtc
    11341 acagcttttg gaattaacgt tgacgagcag aaatcgaaat gcagaagaac ctattcctat
    11401 gtgcggtgta cctcaccatg cagcacaagg atatatcgat gccttgattg aaaaaggcta
    11461 taaagtagcg atttgcgagc aggtagaaga tccaaagacg actaaaggga tggtcaagcg
    11521 cgaagtgatc cagctagtca ctcctggtac agtcatggac agcaaaggat tgtcggcaaa
    11581 agacaacaat tttttaacag ctgtagttag tcaaggaaat gaatttggct ttgcttatgc
    11641 cgatttaagt acgggagaat tgaagacggc tcggttgcat gatgaagaag ctgttttaaa
    11701 tgaagcctct gcattgcaga caaaagaact cgtattaggc agtgagatca ctgataccct
    11761 tcgtgaacag ctaagcgggc gtttagggct agtcttttct caacaaaatg agatggaaga
    11821 aaacgcggaa tttagctttt tgacaagcga actagtcgat ccgctggaaa aagaagcaac
    11881 cggcaaacta ttgacttatt tatcggtgac acaaaagcgg agtttagctc atatccaaaa
    11941 agcagtagaa taccaaccag atcatttttt gaaaatggat tattattcaa aattcaacct
    12001 agaattaagc caatctattc ggactgggaa aaagcacggc actcttctat ggttgttaga
    12061 tgaaacaaaa acagcaatgg gtggccgttt actaaaacaa tggctagacc gtccgcttat
    12121 ccaggcaaaa caaattaaag caagacaaga aatggtcgct tctttgctag acagctattt
    12181 tgaacgtatc gatttgcagt cagcattaac gaaagtctat gatctggaac gcctagcagg
    12241 tcgagtagct ttcggtaatg tcaatgggcg agacttgatc cagctgaaaa cttctttaga
    12301 acaagtgcca atgatcagag ggttgattga aggaatcgat caaggtcaat ggcaaagtct
    12361 gctttcagaa atgcagccga tggaccatct cgtccaattg atcgaccaag ctatccaaga
    12421 tgatccgccg ttacaaataa cggaaggaaa catcatcaaa gatggattca atgagcagct
    12481 cgatatgtac cgttctgcta tgagaaacgg aaagaaatgg ttggcagaac ttgaagcaaa
    12541 agagcgtcaa gaaacaggaa tcaagaactt aaaaatcgga tttaaccgcg ttttcggtta
    12601 ttatatagaa attacaaaag caaatcttgg aaatgcagaa ctggagaagt atgaacgaaa
    12661 acaaacttta gcaaatgcag agcgtttcat cacaccagaa ctaaaagaat tggagacaca
    12721 aatcctcgaa gcagaagaaa aatctgttga tttagaatat cagttgtttt tagctgtgag
    12781 agaagaagtc aaaaaggcta tccagccgct acaagtactt gcaaaagcaa tcagtgcagt
    12841 agatgtgcta caaagttttg caacgatcag cgaacgctat cagtatgttc ggccagaact
    12901 tgtcagtgac aagcatcagc ttctgatcaa agacggacga catcctgtag tagaaaaagt
    12961 attaggacat caggaatata tccctaacag cgtagaaatg gcagaagacg aaatgatctt
    13021 gctgattaca ggaccgaata tgtctggtaa aagtacgtat atgcgacagt tggcattaac
    13081 tgttctgatg gcgcaaatgg gctgtttcgt tccggcaaaa caagcagttt tacctatttt
    13141 tgatcggatt tttacccgaa ttggtgcaag tgacgactta attgctggac aaagtacttt
    13201 tatggtagag atgatggaag ccaatcaagc cctgcgttat gctacgccaa acagtttgat
    13261 tttgtttgac gaactagggc gaggaacagc aacctatgac ggaatggcgt tggcccaagc
    13321 aatcatcgaa tatatccatc gtcatgtaca agcaaaaaca ctcttttcta ctcattatca
    13381 tgaactgacg gtacttgaga aagaacttcc gcagcttaaa aatgtccatg ttggagccgt
    13441 tgaaaaagac ggagaagttg tcttcttgca taaaatgatg gatggacctg cggataaaag
    13501 ctacggcata catgtggcaa agatcgcagg attgccttcc aatctactag aacgagcagc
    13561 agatatcctg catacgctag aaaatggcga taacggacac catactgttc cagctgaagt
    13621 agaagagaaa actaaaacag ccaaacagga gcaaataaaa ccacctgcag aaaaagtaaa
    13681 tcaagaccat atacaagacc gtgtaaaaga agaaaaccaa cagctttctt tattcagtga
    13741 attatccgaa aatgaaacag aagtcattga atcactgaag caaataaatt tactagaaat
    13801 gacgccaatg gatgcactaa acacattata tgaattacaa aaacaactgt aggaagaagg
    13861 cggatatcga tggccaaaat ccaagaatta tctgaacgtt tagctaatca gatcgctgcg
    13921 ggagaagtag tggagcgacc agcttccgtt gtgaaagaat tagtggaaaa tgcaattgac
    13981 gccggcagta ctcagattga tatcttagtt gaagaagcgg gactgcggac gatccaagtg
    14041 attgataacg gagaaggcat tttggcagac gacgtagaga atgccttcaa gcggcatgcg
    14101 acaagtaaga tccataatcg cgacgatctt tttcgcatac gaacgctggg ctttcgaggg
    14161 gaagctttgc caagtattgc ctctgtttct gaaatgactc tggaaacggc gaatcaggaa
    14221 gaaaaacaag gcacctatct gtcgctgaaa ggcggagaag ttattgagca tcgaccagca
    14281 ccactgcgtc aaggaacgaa gattaccgtc agcaatctgt ttttcaatac gccagcccgc
    14341 ttgaaatacg tgaaaacact gcacacagaa ttagcgaaca tcggggacat cgtcaatcga
    14401 ctggcattga gtcatccatc gattgctttt cgtttagtac atgatggaaa caaaatgctg
    14461 gcaactgctg gaaatggcga tctgaaacaa acaattgcgg gaatctacgg attatctacc
    14521 gcaaaaaaaa tgctgaaaat cgaaggaaaa gatctagatt ttgagttatt tggctatgtt
    14581 tcattgcctg aggtgactcg tgccagtagg aattacttat cgacgatcat caatggacgt
    14641 tttatcaaga acttttcctt gaataaagca atcgttgcag gttatgggtc aaaattaatg
    14701 gtcggtcgtt tccctattgc tgtattggaa atcaaaatgg acccgctttt agtagatgta
    14761 aatgttcatc cgacgaagca ggaagtccgg ctgtcgaagg aaaaagaact aacagagcta
    14821 attagtaacg ccattcaaaa agcattgtct caagaaaatc tgattccaag tgcagcggat
    14881 aatctacggt ttaagaaaaa agtacctgat cagcctaaaa cagaacaaat cgaaatcgat
    14941 ttgtcctacg cttttgaaga agaaaaacct aaaaagccaa gtagtttgaa ttttgatcga
    15001 gagacaggta cctttttcgt agaagaacta aagaacacat ttgttgacag aattgttgat
    15061 aagtctgtgg aaaatgttga aaactattct ggtttttctg aagaaaacac cacttatcca
    15121 gaaaaaacag cgaaaacggt ggataagttt ggtgaaaatg ttgataactt tgtagaaaaa
    15181 acagtggaaa aatctgaaaa gaaagaattt cccattgtgg ataacatgga gaaaacaaat
    15241 gaagaacaag cagataaatc cgtagaagag gatgaaaaga tttacgagga agaattgaca
    15301 ctccatcctg aatttgattt cactcaagga aacgacaaaa cattagaaca agccatcaag
    15361 aaattagaaa cggaaaaacc agtacaacgt tttcctcagt tggaatattt tggacagatg
    15421 cacggaacgt atctttttgc ccaaagtagc gatgggttgt acatcattga tcagcatgct
    15481 gcccaagagc gcattaagta tgaatatttc cgggaaaaaa ttggggaagt atctgatgat
    15541 ctgcaagaat tgcttgttcc atttgtgtta gactatccaa acagtgatgc tttgaaatta
    15601 aaagagcaaa aacacttgct agaagatgca gggatttatt tagaagaatt tggtcaaaac
    15661 agctttattg tacgggccca tcctacttgg tatcccaatg gagaagaaga atcgattatt
    15721 cgggagatga tcgatatgct gctgacaact ggaagtgtga gtgtaaaaaa attccgtgaa
    15781 gcaacagcaa tcatgatgag ttgcaaacga tcgattaaag ccaaccatta tttgaatgaa
    15841 gcacaagcac gtgtgctgct gaaggatctg gcacgatgcg aaaatccttt caattgtccc
    15901 catggccgtc cagtattgat tcactttacc aattcggata tggaaaggat gttcaaacga
    15961 atccaagacc cgcattaagt caaagagaag agggaaaaca tgaagattgt attagcatcc
    16021 caatcaccaa gaagaaaaga gttattggct catatcgttt cagaattcga gattgaacct
    16081 gctgatatcg atgaaacgcc atttccagac gaacagcccg tcgattatgt tcgtagaatg
    16141 gctgaagaaa aagcacgaac tgtctgggaa caagatgaaa aagaagacca tttagtgatt
    16201 gccagtgaca cgactgttgt tctcaatcaa gagatcatgg gtaaaccaga agatctggct
    16261 gaggctgaat tcatgctgaa aaaactaagc ggggaaacac atactgtata tacagctgtt
    16321 gttttaaaaa caaaggaacg agaagaacgg atactagcag aagcacatgt cactttttat
    16381 cctttgacag acgaagagat caaacgctac ttggagacgg gggattatgc ggataaggca
    16441 ggggcatacg gcatccaaaa tgctgcgagt gtattcgtca aagaaatttc tggagattat
    16501 tacagtatcg taggatttcc gattggtgct gtcaatcagg cactgaaaac attcatttaa
    16561 acaaaaaagc ggactatctg attttcgatt gaaaatccat gatagcccgt tttttttatt
    16621 gaaaagatta cttatctact ctgactaaga ttttacttca gctttaccga ctgcttcgcc
    16681 cgggcgaaca agtcctgatt ggtcaagaga aagtcctgca actttttcat tattggtcaa
    16741 agcaacaata atgtcagttt tcttgccagc ttgttctatt tctggcaaat ccatttcagc
    16801 aatcagggtc tctggtgtga caaggtatcc ttctttcacg aatacattga aaggaacacc
    16861 ctttagttca acagtatcta atcccatgtg aacaagtact tccagcccct cattagaaag
    16921 aataccaatg gcatgttttg tttcaaagac actcgtcact ttaccgttta ctggtgcata
    16981 gactttgccg tttgacggtt cgacagcata accgtcaccc atcatttttt gtgagaaaac
    17041 tgggtcattt acttcagtta tttccttgat ggtccctgca gcgactgcga ataatgtttc
    17101 ttttgttgca actgccgtac cagttgctga aacaggttcg aaagactgtg gcgttgctgt
    17161 tgcgccattt gctgtttgaa gttgtacatc agcagcattt tcaggaacag caggatcaat
    17221 cttattcaaa attccctgac gtctaaagat gatcgtcaag ccaaatggaa tgatgacagc
    17281 aatgatcatt gcgatgatga aaggtaccca tgtttctgct tggatagcta gtattcctgg
    17341 caaaccgcct actccgatcg cgttagctcg aacacccatc aagttagcaa acatgccagc
    17401 taatccagag ccgaccattg cagcgacgaa aggatagacg tatttcaaat tgattccgaa
    17461 catagcaggt tcagttacgc ctaagtaaca agaaatcatt gctggaatcg agatttgttc
    17521 ttctttttta ttcccacgat gtaagaagat gatggctaag actgcagagc cttgggcgat
    17581 atttgataaa gcaatcatcg gccataaatt cgttgatccg aaatctgcaa tcagctgcat
    17641 atcgatggca ttggtcatat ggtggagacc agtaatcact aaaggagcat acaggaatcc
    17701 gaatacggca ctaaacaacc agctgataga agacgtcaat ccagtattta cgatatttga
    17761 gatccagctt ccgactgtcc agccgatagg acctaaaata acgtgtgcag ctaaaacagt
    17821 tggtaacaat gaaaacaatg gaacaaaaat catcgagatc gactgaggga tatatttgcg
    17881 gaagaagatt tctagatacg ctaacataaa ccctgccagc atggctggaa taacttgcgc
    17941 ttgataacca atcatctgga cttgagcaaa accaaaatcc caaaatggaa tatctgctgc
    18001 ggctgtggaa gctacactat aagcatttaa taattgcgga gaaactaacg taattcctaa
    18061 aacgattcct aatatttgtg tagtacccat cttttttgca atactccaag tgatacctac
    18121 tggaagaaaa tggaaaattg cttcacccgg taaccacaaa aaggcattga caccattcca
    18181 aaacttcgag tgttcaacga ttgttccacc aagactttca aactggatac cttcaagtac
    18241 atttctgaat ccaaggatca atccaccgac aatgattgca ggaatcagtg gtgtaaagat
    18301 ttctgctaaa acggcaatag cacgttgaac gggatgaagg ttttgttttg cagctgcttt
    18361 tccttgttct ttggaaaccc cttcaactcc agatactgca acgaagtcgt tataaaaagt
    18421 agaaacatcg tttcctatga tgacttggaa ctgtcctgca ttcgtgaaca tcccttttac
    18481 gctaggtata tcttcgatcg ctttttcgtc cgcttttcct ggatcattca ggacaaaacg
    18541 catacgagtc gcacaatgac taactgcagc aatattttct tttccgccga tatcatgtaa
    18601 cagcttctcg gcatctgctt gatattttgc catatcaata aacccctttc tcttaacttg
    18661 tctatgcaag ttgtttcttc atttactata ctttttttcg gagagaatcg caagcgtttt
    18721 attaaaaagt acgagagaaa atgatatcgt tttaaaaagc ttaaaataag cttttcttaa
    18781 aaataggaac attgaaatac aaaaagagct gtagtatagt gaagaaatga tggaagaacg
    18841 agtgagggaa aaaacatgaa taagttcaat gaaatttttt tagatttgga acagaaaatt
    18901 ttagcgaaag aatatcctcc gcattcgctt ttacccagtg agaaccaatt gatcaaaatt
    18961 tatggtgttt cacgagaaac aattagaaaa gcgctgaatc ttttgactac ggaaggttat
    19021 attcaaaaaa aacaaggaaa aggttcgatc gtactggatc ggaatcgctt cgactttcct
    19081 atttctggat tgactagcta taaagagcta caggagaccc aacgtattcc aagtgaaacg
    19141 atcatccata cgttagaaga aacagaagtg acaaaagcat tgaacgagat cactggctgg
    19201 gagatcggtg cgcctgtttg gcatttgata cgcgaaagaa aaatcaatgg cgaagtagtt
    19261 atattagaca ccgattatct attaaaggaa atcgttccta ttttaactcc agcacaagca
    19321 caaggatcga tctatgaata ttttgaaaat gagctttctt tgacgattgc ttacgcgcaa
    19381 aaggagatca cagtagaaga actaacggaa atcatgaaaa cagcgatgga tcttcacgat
    19441 gacacttatg cagtagtagt cagaagcctc gttcatctgg aagatacccg ctgtttcgag
    19501 tattctgagt cggttcaccg attagataaa ttccgtttcg ttgagtttgc ccgacgccga
    19561 aaagtgtaaa tagttcaaaa gaaagcaaat tgttggcatc tgtccacttt ggcgctatga
    19621 taggatcaca aagggggcat ttttaatgga taaaccaata agaccagaaa aagaagaact
    19681 gaaagaaaag ttatcaccca tggcttatgc agtcacacaa gaaaatgcaa cagaacgacc
    19741 atttagcggg aaatatgatg atttttacga aaaggggatc tatgtagata tcgtcagcgg
    19801 tgaaccgtta ttcagctctg cagaaaaata tgatgcaggt tgtggctggc catcattcag
    19861 caaaccaata acgaaaagac aagtgcgcga aaaagccgat ttttctcatg gcatgcatcg
    19921 aatagaagtt cgaagcaaag aagcagattc tcatctcgga catgtgttta ccgatggacc
    19981 agtagatcaa ggtggtctac gttactgcat caattctgcc tcactgaaat tcattccata
    20041 tgaaaagatg gatgaattag gttatgggga attcaaatca cttgtagaat aatggaaata
    20101 cacaaagagc ggtacaatac ggggatttac tcgatcgtcc gctctttttt tattcaagcg
    20161 attgctattt gaaagaaacg ctccctagac tccttttttc acaaggtgaa atgtgctaca
    20221 ataaagggaa cgtatgtgtg caaaagaaag aggactagaa tatgtatgaa tatctgacag
    20281 gtgtggttac ctttatcaac ccctattaca tagtagtaga aaccaatggt atcggctacc
    20341 agatcgcact aggaaatcct taccgctaca gtagcaaact aaatcaaaaa ataaaaattt
    20401 atgtccatca ggtaatacgt gaagatgcgc atcttctgta tggatttgat tcgctagaag
    20461 aaaagcaact gtttttgcga ttagtaagtg tttcaggaat cggtccgaaa agtgcccttg
    20521 caatcatggc aagcgaagac cactccggtt tgattcaagc agtagaatcc agtgatgtca
    20581 cttatttgac gaaatttcca ggagtaggga aaaagacagc acaacaaatg atcttggatc
    20641 taaaaggaaa attcggtgag ctgagtatcg atacaccttt tagtctattt gatgaagcaa
    20701 acacaaaaga cgctacagct ctatctgaag caatggaagc tctctcggct cttggttaca
    20761 gtgatcgaga aatcaaacgt gtagaaaaac aattaaaaga agtagataat cagacaacgg
    20821 atgagtatct acgccaagca ctcaagctaa tgatgaaaaa ataaggagga gaccaaatga
    20881 cagatgaata cttgttatca ccagaatctg gcgaaaatga actgagtttg gaaaaatctc
    20941 ttcgaccaca gctgctttct caatatatcg gacagagaaa agtcaaacaa gaacttcaga
    21001 tttacatcga agctgccaga aatcgggaag aacctttaga tcatgttctg ttgtacgggc
    21061 ctcctggatt aggaaaaacg acgatggcca tggtcattgc taatgagatg accgtaaata
    21121 ttcgtacgac gagtggccct gctatcgaac gtccgggtga cttagtagca atcttgaatg
    21181 aactggaagc aggggatgtc ctgtttatcg atgagatcca tcgattacct agagtggtag
    21241 aagagatgct ttattcagct atggaagatt tctatgtaga tatcatggta ggacaagggc
    21301 caaccgcaca tccggttcat ttccctcttc ctccctttac tttgattggc gcgacgacac
    21361 gggcaggtat gctttctgca cctttacgag atcgatttgg catcatttct catatggaat
    21421 attatgacga acaggatctg caggagatcg ttttacgttc ttcggatatt tttcaaacag
    21481 agatcattga agaaggggca ttggaaattg ctcgccgatc acgaggaacg cctagaatcg
    21541 ctaatcgctt gctcaaacgg gttcgtgatt ttgcgcaagt ccaaggagac gggaaaatcg
    21601 atcgtcctat agcggatcag gcacttactt tgctacaggt cgatcaggct ggattggatt
    21661 atgttgacca gaaattgttg cgaacaatga tcgagttata tggcggcgga ccagtagggt
    21721 taagtacgct ttcagtaaac ataggagaag agcgtgagac ggtagaagat atgtatgaac
    21781 cgtatctgat ccaaaaagga tttttaaagc gtacacctag agggcgaatt gctactgctt
    21841 atgcctatga acattttggt tacgactatc atatatgatt tttgctttta gattggagga
    21901 aaatgaatga gtgatacaac acgtacgaaa caattgatca aaaacgtatt gattgatttg
    21961 tgccaaacgc aatcttttcg aaaaatcagc gtccaaaaaa tcgcaaacga agcaaaaatc
    22021 aatcgacaaa cattttatta tcattttaca gataaatacg atttgcttcg ttgggtctat
    22081 tgtgaggatg cattgcatta tttagatcca caatgtcttt cacttgataa ttgggaagag
    22141 caagcattga aaatgctgaa agcaattgct gagaagaaag aattttatgc aaatactgtg
    22201 ctttctgacc cagaaatttt acaaaaagag ttttctcaac tgatccaaaa atcatttatc
    22261 aagatttttg aacaaatgga tgaagaaaga caactttctg caagagacaa actattttat
    22321 gctcgttttt tttcttacgg ttgcagtggt gtattagtca attggatcac gaatgaatat
    22381 gaagaaacac cgatggaaat cgctatgcag cttttccgtt tagccaagga tacggaatta
    22441 tattcttatc gtctttatgc aaaagaagag ttggaagaac agtaatagaa aaattttttg
    22501 ttggaaaagc aataatcgct aaaaggagat ggggaaatga caaaaatttt atttgtttgt
    22561 ttgggaaata tttgccgttc accgatggca gaaggcttgc tgagaaaacg aatagcatta
    22621 gaaggaaggg aagcagaatt ttttgtggat tctgctgcta caagcacgta tgaagttgga
    22681 aagacaccgc accctggaac gaaaaaaata ttaaaccaag aaaaagtaga tatgacgaat
    22741 atggttgctc ggcaaatcac accccacgat tttgaaactt ttgattggat cattggcatg
    22801 gatcaagaaa atgtagaaga actgaaacga agagcaccac gctcagcgca ggggaaaatc
    22861 catttgtttt taagtagcat tcctggaaaa gaaaaagaaa atgttcccga cccatactat
    22921 accaataact ttgatgagac atatcacttg atcacagaag gcctgaatca ttggtggaat
    22981 atttggattg atgaaaataa aataacaaat aatttgtaaa gttaacgctt tctttttaag
    23041 gcgatgttag agcatttcct tgtttttttg taaaatgtta ggtaaaataa aattaattaa
    23101 gtaacacttt cttagctaaa ggaggagtgc attcgatgaa cgaagagaca gtatcgccaa
    23161 tgaagaagct tacgaagtta gttactcata cttcgtatca actttttgat tcttttgtaa
    23221 atgacactga agaacatgct aagaatgtac gattgcaagg aaagtttatt cttgagctgc
    23281 aaaaagctgc tactgaacat agtctagtta tcttacaagt aagagcaaat cgtttgagta
    23341 gcaagtatga aacgatctca ggctgggtgg cgacaaaaac ggtcgaaaaa gaccgagtga
    23401 tgatccgcct acaaaacgaa gagcagcaga tccggatggt tcctgtagaa caaattgaaa
    23461 aaataacaat cctttcacca gcaggggaac aggaacggtt atcaaaataa tttataccag
    23521 atagaaaagc acgtatgagc ttgtaccatc aatcattact aatcaaaaat aaccgaatgc
    23581 tttaagctga tatcagtaaa acggaacgtt ttaggatgag tatcatagca tgacagcatt
    23641 cggttgatta gttgaatcga ttggatggta caagtttttt tgataaaaaa aggtcctgct
    23701 agccggggag ctagcaggat aaggagttaa aaatgaaaaa gtgttgttag ggttgtttgt
    23761 tggtatgctt atataatagt cattagttgt gaatattttg tgacgaaagt tttcgaaagt
    23821 tgttaag
//
LOCUS       DACGMI010000045        23659 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.046, whole genome shotgun sequence.
ACCESSION   DACGMI010000045 DACGMI010000000
VERSION     DACGMI010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23659
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.046"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            299..1960
                     /locus_tag="IXT46_001996"
     CDS             299..1960
                     /locus_tag="IXT46_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4947899.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2377)
                     /locus_tag="IXT46_001997"
     CDS             complement(2030..2377)
                     /locus_tag="IXT46_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAQ4947900.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2461..3402
                     /locus_tag="IXT46_001998"
     CDS             2461..3402
                     /locus_tag="IXT46_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4947901.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3403..4446
                     /locus_tag="IXT46_001999"
     CDS             3403..4446
                     /locus_tag="IXT46_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4947902.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4452..5522
                     /locus_tag="IXT46_002000"
     CDS             4452..5522
                     /locus_tag="IXT46_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947903.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5512..6465
                     /locus_tag="IXT46_002001"
     CDS             5512..6465
                     /locus_tag="IXT46_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4947904.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6477..7487
                     /locus_tag="IXT46_002002"
     CDS             6477..7487
                     /locus_tag="IXT46_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4947905.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7772..8593)
                     /locus_tag="IXT46_002003"
     CDS             complement(7772..8593)
                     /locus_tag="IXT46_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAQ4947906.1"
                     /translation="MNRFASKEEEKLYYEHEASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8690..8968)
                     /locus_tag="IXT46_002004"
     CDS             complement(8690..8968)
                     /locus_tag="IXT46_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947907.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9236..11245
                     /gene="metG"
                     /locus_tag="IXT46_002005"
     CDS             9236..11245
                     /gene="metG"
                     /locus_tag="IXT46_002005"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAQ4947908.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11724..12311)
                     /locus_tag="IXT46_002006"
     CDS             complement(11724..12311)
                     /locus_tag="IXT46_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947909.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12486..13808
                     /locus_tag="IXT46_002007"
     CDS             12486..13808
                     /locus_tag="IXT46_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4947910.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13963..14739
                     /locus_tag="IXT46_002008"
     CDS             13963..14739
                     /locus_tag="IXT46_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAQ4947911.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14732..15301
                     /gene="rnmV"
                     /locus_tag="IXT46_002009"
     CDS             14732..15301
                     /gene="rnmV"
                     /locus_tag="IXT46_002009"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAQ4947912.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15294..16178
                     /gene="rsmA"
                     /locus_tag="IXT46_002010"
     CDS             15294..16178
                     /gene="rsmA"
                     /locus_tag="IXT46_002010"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAQ4947913.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16629..17258
                     /locus_tag="IXT46_002011"
     CDS             16629..17258
                     /locus_tag="IXT46_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947914.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="IXT46_002012"
     CDS             complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="IXT46_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAQ4947915.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18700..19122
                     /gene="mgsA"
                     /locus_tag="IXT46_002013"
     CDS             18700..19122
                     /gene="mgsA"
                     /locus_tag="IXT46_002013"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAQ4947916.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19445..19981
                     /locus_tag="IXT46_002014"
     CDS             19445..19981
                     /locus_tag="IXT46_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAQ4947917.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20021..21784)
                     /locus_tag="IXT46_002015"
     CDS             complement(20021..21784)
                     /locus_tag="IXT46_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947918.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHFSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21787..23502)
                     /locus_tag="IXT46_002016"
     CDS             complement(21787..23502)
                     /locus_tag="IXT46_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947919.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
BASE COUNT         7629 a         4322 c         4799 g         6909 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgaggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt ttttcatttg attgctcctt tatttttggt
     2401 tcattatcta ataatgtagc gaaacatctg tcagaagtca aaagctaggg ggaaacatta
     2461 gtgaatagtt atatcaaata tgtattaaaa cgtgtctttt tcatgatcat cacgctttgg
     2521 ttaattgcaa caatcacctt tttcttgatg caattgctgc cgggcacgcc atatacgaat
     2581 caggaacgtt tgagtcctga aacaatcgag atgctaaata aacaagtcgg tttggataaa
     2641 ccagttatcg tacaatatgg gatttatctt tctaatttgc ttcaaggaga ttttggaatt
     2701 tccttccaat ttaaaaacca gccagtcgca catttgttag ctggaagaat cggaccatcc
     2761 ttgcagttag ggttacaggc aattatcttt ggaacagtcc tagggacgat tttaggaacg
     2821 atctctgcca tgaagcaaaa tacatgggca gatacatctt ctacactcgt agcgatatta
     2881 ggtcgttcca ttccaaactt tgtatttgct gttttattac aatatatctt tgcaatcaaa
     2941 ttacaagttt tgccaatcgc aaaatgggat ggctttgtgt acacaatctt accaacaatt
     3001 gcgttggcca tgtcgccgct tgctgactct gctcggttta tccgtacgga aatggtggaa
     3061 gtactgcata gtgattatgt ggaattagca aaagcaaaag gattgagccg ttgggaaatc
     3121 gcctttaaac atggtcttcg aaatagtttg attccattga tgactttatt aggaccgtta
     3181 gctgtagcat tgatgaccgg atcactggtg gtagaaaata tctttgctat tcctggtatc
     3241 ggggaacaat tcgttaagtc aatcacaaca aatgattatc ctacgatcat ggctgtaacg
     3301 atcctttact catttatgct gatttttgtt attttgatcg tggatctatt gtacggtcta
     3361 gttgatccaa gaattcgtgt ttcagaaggg agccgaggat aaatggaaat gataccaaag
     3421 cgttatgaaa cagttgcaga tatccctgcg gatgaatttc ttccattaca aaaaaatacc
     3481 gaagaagaac gtgaacagat tactgcacct tctttgaatt ttatccaaga ttcatggcgc
     3541 cgtttaaaga aaaacaaagc tgccgttatt tcaatggttt tactattggt catcattttg
     3601 atctctgtga tcacaatctt tgtttctcct catgatccaa ctgcccaaaa cgtggcttat
     3661 atcaatttgc ctcctcgtat tccgggaatc aatatcgatg gattgaatgg aaaagcaatg
     3721 gttggtggtg aacttgttga taaatatgct caagcaaacg tcccttcaaa cgtaaatttc
     3781 tttttaggaa cagacggttt gggacgtgat gtattaagcc gcttatttat gggaatgaga
     3841 atctcgttgc tgatcgcatt tattgctgca ttactagatg taacgattgg tgtagcttac
     3901 gggttggttt ctggtttgtt aggcggacgt gtcgataacg tgatgcaacg ttttttggaa
     3961 atcttatcag gaattccaaa cctcgttgtc atgattttga tgttggtcgt ttttgaacca
     4021 ggaatttttt caatcgtggc tgctatggcc atcacaaact ggataccaat ggcacgtatc
     4081 gttcgtgcac aaacaatgaa attaaaagat caagaatatg ttttagctgg attgacatta
     4141 ggtgaatcaa gaatgaaaat tgcattcaaa catattttgc cgaatatctc tagtgtcatt
     4201 attattcaaa tgatgtttag tattccatct gctattttct tcgaagcctt tttaagcttt
     4261 atcggtttag gtcttacgcc tccgtcagct tcattaggaa cgatgttgag cgaagggtac
     4321 aagacattcc tgtatctgcc ttatctatta tggattccgg cagtaacttt atcggttatc
     4381 atgattggct ttaacttact tgctgatgga ttgcgtgatg cctttgatcc taaaatgaaa
     4441 gagtgaagac gatgacgaaa attttagaag tgaaagactt agaaatctct tttgatacgt
     4501 atgctggaaa ggtacgagcg attcgcggtg tcaattttca tttgaataaa ggagaaacat
     4561 tggcgatcgt tggggaatct ggaagtggaa aatcagtgac gaccagaagc atcatgcgct
     4621 tgctgtcaag caacgccaat atagatgctg gtcaaatcct ctttaaaggt aacgatatcg
     4681 ttggaaaatc agaaagagag atgcaaaaaa tccgtggtaa agaaatagcg atgattttcc
     4741 aagatccaat gacctcttta gatccgacga tgcccattgg gaagcaagtc gctgagtccc
     4801 ttagaaagca taataaagtt tcaaaaaaag agggacaaaa agctgcatta gaattgctta
     4861 aattagttgg aatacccgaa gctgagaaac gtatcaacag ttatccgcat cagttctcag
     4921 gaggtcagcg tcaacggatc gtgatcgcga ttgcactggt atgttatccg gaaatcctga
     4981 ttgctgatga acctacaaca gcgcttgatg tgactattca agcacagatt ttggagctgc
     5041 tgaaagaaat tcagacaaaa atcgatacat caattatctt tatcactcat gaccttggtg
     5101 tagtagcgaa tgtcgctgat cgtgtcgctg tcatgtatgg aggaagaatc gttgaagttg
     5161 gaacatcgga agaaattttc tacaacccgc aacatcccta tacttgggga ctgcttggtt
     5221 caatgccgac attagatagt gcgaacgatc gattgtatgc tattcctggt tctccaccgg
     5281 atttattgaa cccgccaaaa ggagacgcat tctatccaag aaatgaattc gcgatgaaaa
     5341 tcgatgcaga acaagaacca ccattttttg aactatcaaa aacacacaag gcagcaactt
     5401 ggctacttgc tccgcaggca cccaaagtga caccgccaga agaaatccaa cgtcgctggg
     5461 ctatctttaa agagaaacaa aaacatactt acggtcaagg aggaattgct gatgccaaat
     5521 aaactacttg aagttaaagg attgaaacag tatttcaatg taggaaaaaa gaatgaagta
     5581 catgctgtaa atgacatcag ctttcacatt tatgaaggag aaacattcgg tttagttgga
     5641 gaatctggaa gcggaaaatc cactactggc cgtacgatca ttcgcttgaa tgaacctact
     5701 gatggtgaga tattattcga cggtcaagat ataacgaaga tcaaagataa aaaaggtttg
     5761 acgaaattcc ggcatgatgt tcagatgatc tttcaagatc catacgcttc gttgaatcct
     5821 cgtatgaaag tcagagatat cattgccgaa ggaattgatg ttaatggact agctaaatca
     5881 tctgaagagc gtgcaaaaaa agtcgatgat ctattgagaa ctgttggatt gaatccaagc
     5941 cacggtactc gttatcctca tgaattttca ggtgggcaac gccagcgtat tggtattgca
     6001 cgagcattgg cagtaaaacc gcgttttatc atttgtgatg aaccaatttc tgcactagat
     6061 gtgtcgatcc aagcccaagt ggtcaatttg ttgcaagatc tccaaaaaga acatcaattg
     6121 acctatctat ttattgcaca tgatttgtcg atggttaaac atattagtga ccgaatcggt
     6181 gtaatgcata acggcttgtt attagagatg ggaacaagtg atgaaatcta taatcacggt
     6241 gttcatcctt atacagaaag tttgttatct gctattcctc taccagatcc agaccatgag
     6301 agaaaacgca gaagaatcaa atatcaacct gaaccagatg acggacaagt acgtcaactt
     6361 cgtgaaatcg caccagaaca ttttgtctat gcaactgagc aggaagtccc atattacgca
     6421 aaaaaactaa aacgacaaaa ggaatctctt ctggttgcta actaggaggg acatagatgc
     6481 taaaagcttt taaattccgt atgtatccga cagaagaaca aaaacagcaa ttgattcgta
     6541 cttttggatg tgctcgattt acctataacc atttgctgaa aaagcggcag aaaagttggc
     6601 aacaaacagg agtagccaat ttttcgctca cacccgctac attaaaaaaa gaatacccat
     6661 tcttaaaaga agtagacagt cttgctttag caaatgcaca gcttaatttg gatcgggctt
     6721 ttcgcaatta tttcaaggga cgtgccagct tcccaaagct taaaacgaaa aaaagtatgt
     6781 ggcaatctta tacgaccaac aaccaaaccc gtacgatcta tctggaaaat ggctacttaa
     6841 agttaccaaa acaaaaagaa ctaatcaaga taaatcagca tcggccagtt gaaggatcga
     6901 ttcgctccgc tacgatttct gctcgatata atgaagaatt ttatgtcgca ctactttgtg
     6961 atgtttcgcc agtaaaaaaa gaatctttag ctaaatggat cgggatcgcc tatcatccga
     7021 agacattgat ccaaacatct cgacctctag aagtaacttt accaaaattt caccagacag
     7081 aagaaaagct gcaacatgca cagcggaaat tgaatgtgaa agtccgctcc gctcaccata
     7141 gaaagatcag gttagatcag gcaagcaatt atcagaaaca aaagagaaaa gtaatggatc
     7201 tttatctgaa acaaaagaac cagcgagaag attatcttga acaattatct gggaaattgg
     7261 tcaaacaata tgactactta tttgtagaat cttttccaaa agaagaggca catgctgatt
     7321 tttctattca cgactggcat aaattaataa caaaattgcg ttataagtcc caatggtata
     7381 ataaaaaatt tcttttgatc aataccgacg gagcagaaga aagcaattcc gtaagaaaga
     7441 gccaagtagt agaaaaaatg ggcagacatt cggttatcaa gggataaaaa atgaatgaaa
     7501 ctgataggag cgttagggtt agccttgtta ataaaaagtc ttaatgactt ttgtttctag
     7561 gaatttttct tttgaagaaa agctcactaa ttatgacaaa ccaataaaac aatagcagaa
     7621 aaagttcgta cgagcttttt ctgctattgt taatttttta ttcagaaagt ttacgaatac
     7681 atcaaaattc tgaaacaaaa aacgtaactc acaaagagtt gtttttgcgt tttttcttga
     7741 atgattaggt ctgaatcttt tgctcacaac cttattcatg gtgccccggc ttgagctgat
     7801 agatttttga aggacggccg attcctacag gacgttcacc gatctcatcg aaatattgga
     7861 gcatagcttt cttaaaattg gaatgatcga tcgttttata atcgatccct aagaatttag
     7921 caaatacttt tcgagcttcc gtaatcgtga aatctttacc taaaacttgt agaacttgcg
     7981 gctcgtgttc cattttattg actacacggt tgaatgcttt caagatgatt tgactatggt
     8041 caaaagccaa agtatctttg ccagaagact ctccagtgac taaatcaagc gagatagcca
     8101 cttctccgct agataaatgg atcttgttac tatgacgttc tagtgtgaac cagcgtactt
     8161 ccttggcatc atctccggcg attagcggtt cttctccaat aaaggctaag tagctgactg
     8221 tgacgaccca gcctcgcgga tctcgattag gcgtactgaa tgtatgcagt tgctcaatat
     8281 tttcttttga aataaccaca ccagtttctt cctttgtttc tcttaagacg ctttctccag
     8341 ttgactcatc cttttggaca aagccaccag gcaatgccca tgaatttcga taaggatgcc
     8401 cttttctttg gatcaacaaa actttcagct gatcttcttc tttgttatag cacatcagta
     8461 cgatatcgac agtcaaagag ggcttgtcat attctggacg ttcctgtttt tgataccagt
     8521 taagaaattc ttcttcactt gcttcatgtt cataatataa tttttcttct tctttagaag
     8581 caaaacggtt catctgacca cctccattga cagtaaaagt actttttacc ttattgtagc
     8641 agactctgaa aaaaaaccaa ggatttactt gaaaaatcta ggttatcatt taaatatgaa
     8701 aaataaatgg aagtatgaga ttgaataaaa agaaaagcag ataaaacggc aatactttat
     8761 accgctcttc acgaatggca aagaagccac aaataacgat atatacgtca atgataaaac
     8821 gcaaaatcca agctgctgtc ataaaactgt tcaaatgccc atggaggtta aaataaccat
     8881 acatacgaat ataaaaatag ctgaatatta aatgtgctaa tgaaagaaaa gcaatactaa
     8941 gtgtaaaaaa aagatgtttc ttctgcatga ttgttccagt cccttactaa gatagatagt
     9001 ctttattata ccacgtgtga ggggagaaat aaaaagccgt tttttagtag atatgaaaca
     9061 aaacaaaaac ccgcatttat tcaacctatt catcctttta aaggatagat tgaacgtaga
     9121 tagaagtcgt ttatccagtc tttttcattt tgaaaaaaag ctaacagcat gcttttttta
     9181 tggtatacta gcaaggaaac gaattcgcat catgcgataa aggaggaaga gccccgtggc
     9241 agaaaaggaa actttttata tcactacgcc aatctattat ccaagcggca aacttcatat
     9301 cggcaactcg tatactacga ttgcatgtga cgcaattgct cgttataaac ggttgatggg
     9361 ctttgatgtg ttttatctca ctggagtgga tgaacatggt caaaaaatcg aaacaaaagc
     9421 agaagaacta ggtgtaaaac cgcaagaata tgtagataaa atggcggctg atgtcaagaa
     9481 attatggaaa acgcttgata tcagttatga taaattcatt cgcacgacag atgattacca
     9541 taaagcagct gttcaaaaaa tatttgatcg tttattagaa cagggagata tttacttagg
     9601 tgaatatgaa ggctggtact ctgtttctga cgaagaattc tttacagaaa cacaacttgc
     9661 agaagtgtac aaagatgacg aaggtaacgt gatcggtggt aaagcgccaa gtggacacga
     9721 agtagaattg gtaaaagaag aatcatactt cttccgcatg agcaaatacg cagaccgtct
     9781 attggaatac tatgaagaac atcccgaatt catccagcca gaatctcgta aaaacgaaat
     9841 gatcaacaac tttatcaaac caggattaga ggatcttgca gtttcacgaa caacttttac
     9901 ttggggagta ccagtcaaga gtgatccgaa acatgtggtg tatgtatgga tcgatgcatt
     9961 atccaattat attactgcac taggatatgg ctccgaagat gaaagtctat tcgaaaaata
    10021 ctggcctgca gatgttcaga tggtcggtaa agaaatcgtt cgctttcata cgatctattg
    10081 gccaatcatg ctgatggccc ttgatttgcc tctacctaaa aaagtatttg ggcatggctg
    10141 gctattgatg aaagacggaa aaatgtctaa atcaaaagga aatgtcgttt atcctgaaat
    10201 gcttgtggaa cgttatggtt tagatgcact ccgttattat ttgcttcgtg ctgttccgtt
    10261 tgggtcagat ggtgtcttta cgccagaaga ttttgtttcc cgtgtcaatt atgatctggc
    10321 aaatgatcta gggaacttat tgaatcgaac gattgctatg atcaacaaat attgtgatgg
    10381 actcgttcct gactatgcct cacttgtcac tccatttgat agtgaactgt ctacgacggc
    10441 tgctaacgtt gtcggacgtt accatgatgc aatggaaaaa atggaattca atacagcatt
    10501 ggctgaaatc tgggtgctga tttctcgtgc aaacaaatac attgatgaaa cagaaccatg
    10561 ggtattagca aaagacgaag aaaagaaagc tgaattgaat agtgtcatga tccatttagc
    10621 tgaatctttg cgtatcgcag cgatattact tcagccaatc atgacagaaa cgccagagaa
    10681 gatcttcaat caactaggat tggactctga aacaatgaat cttgaaggat tacactttgg
    10741 cgaatttcct tcaggaacaa aagtagttgc aaaaggtaca ccaatcttcc cacgtttaga
    10801 tatggaagaa gaagttgctt ttattcaaga aaaaatgtct gaaggtactc aaacaaacga
    10861 agatacagtc aaatgggatc cagaagaaac agaacttgtt tcaacgaaag aaaaacaaat
    10921 caaatttgat gtatttgaaa aagtagaact aaaagtagca gaagtcatca actgtcaaaa
    10981 agtagaaggg gcagataagt tgctgcaatt ccgactagat gctggagaca gccaagaccg
    11041 tcaaatcttg tcaggaatcg ctgaatttta tcctgatcca agcgaattga tcgggaaaaa
    11101 agtcgtcatt gtagcaaatc tgaaaccacg aaagatgcgt ggacaaatca gtcaaggaat
    11161 gatcctttct gcagaagcac cagatggctc tttacaagta atcgaagcac caaaatccat
    11221 gccaaatggc tcagaaatcg catagaaatt caaagggggt atgacactag ttgtgtcata
    11281 cccccttttt ccgaaatttg agaagcaatt ttcgtaaatt ccttcttatt acttgaagcc
    11341 aatcatataa tacagaaaca gagaactatc caaaataaat cctagaaaaa gaagtacgag
    11401 cttcgctgat ttttgttaat ttagaataat actaatagga atcgtaaaaa cagaaaaaaa
    11461 gcataatgat aaagggtcgg gcagatttta attgattcat ctggtactct tttttattgt
    11521 ccttacattc ataaagtttg aatgcaatga ctttattaca tctatattta tatctaacag
    11581 tagcgttgat gtgttaatta taagttctat cactttatgt tcaattagtt tgtgctctta
    11641 tatgtgtgat tgaaaatata gataaaaaaa caatcatcgg ctttgacttc gatgattgtt
    11701 ttctttattt tgtaaaaatc ctatcacttg attttatggt aaccttttat ttttgtcttc
    11761 aaacggcttg gtaagagagc agtaagcagt gcaaatggga tcgaaaagac ataccagaaa
    11821 atcgtacgtc cgataccata atgttgatag agctttgtca acatcacgtg taacaagatc
    11881 aaccctaaaa gcaaggagcc agctataaac caatgattat cccaatgcat gacttcacta
    11941 agtgccatca ctccaaaagg atagaaataa aaatagatcc cgactaaggt catccgccag
    12001 ttctttgtaa atgttccgat attcaataaa aagaaaatcg ctgaaagcaa aataccgata
    12061 ggcggaaaaa gcccaaccaa aaaggaatac aacatccccc acaagatcat cacaggacct
    12121 ttgatcaatg caacgattgc gatgaacaaa gtcagcaata ttagtttttg tgataacgtt
    12181 gcaacagtca ttaatccaaa taaaattaat gtgaaccaat gccaatggga ctgctgttgt
    12241 tctttacggg aaaaatcgac ccggttggat aaataatctg ctaatttcgg ataagaacgc
    12301 ttaaaatcca taaactgttc ctccttcgtg gaaaaggtag gtttagtata cgaaaaataa
    12361 aaaagaaata catccgtctt aagagggagt ttttcactga aagtggagaa aaaagaatgg
    12421 taaattaaaa tattctcagt tatactgaaa attataccaa atttcaaaga agaaagagga
    12481 tgggaatgaa aggcaaacta aaacgagaaa tcaatctgtt tggcgcatta gctaccgtta
    12541 tgggaaccgt gatcggtgca ggcgtcttct tcaaaactgc tgctgttact gctagtactc
    12601 agtctacaag tttgacattg ctagcttggc ttttgggtgg tttcttaacg atctgtgctg
    12661 gattgacagt ggctgaatta gctacagcaa tcccggaaac tggtggagct gtaaaatata
    12721 ttgaagctgc gtatggaaaa ttgcccagct ttttattagg atgggcgcaa agcttgattt
    12781 actttcctgc taatattgct gcattatcga ttatctttgc gacacaattg acgaacttat
    12841 tacaattatc taccgattat cttttgttga ttgcagtgat caccgctgtt tctgtgacag
    12901 ggttgaattt gttagggaca aaagtcggtg cttctgtaca atcagtgacg ttgattgtta
    12961 aattaatacc aattgctgtg attgtcatat ggggattatt gaccccagga caaggaactg
    13021 tccagttatt tccaatcgaa gctggaaaag atgttacttt tgtcgaagga ttgagcagtg
    13081 cgttgttagc aacgttgttt gcttatgacg gctggttagg tgtcggtgca atggcagggg
    13141 aaatgaaacg gccggaaaaa gatttgccta aagcaattat tcttggtttg agttttgtaa
    13201 cagtcgttta tctattgatc aattttgttt ttttgaaaac tttgccgatt gatcatcttg
    13261 ccggtaattt gaatgcagct tctgaagcat cagacgtcat ttttggagga atcggtggaa
    13321 agctggtcac tattgggatc ttgatctcgg tatacggtgc attgaacggt tatacactaa
    13381 ctgggatccg cgtgccttat gcgatggctt tagaagacga gctacctttc agtaaacagc
    13441 tgacaaagct ttcaaagaag tttacggttc cttatgttcc tgcggttttc cagttagcag
    13501 tagcttgtat tatgatgagc cttggttctt tcgacttttt aacagacatg ttgatttttg
    13561 tgatgtggct attcagttta ctgattttta tcggtgtctt tattttaaga aaaaaagcgc
    13621 cggaattgcc acgtccatat aaagtaccac tttatccaat cgttccgatt attgcgattc
    13681 tcggtgctat tttcatttta ggtatgacga tgatgacgca aacgaaatta gcattgatcg
    13741 gtataggtgt taccttgata ggtatcccag tctattatca aaaaaagaaa aaacgctcag
    13801 aagagtaaaa tatttcaaca acagacagaa aaagtacgaa ctaggtcctc tagatcttcg
    13861 tgctttttct atttcaataa aacaagttct tctattttga tttttgctac ttctgcaagt
    13921 agtgcttatg tgctaaagta agaatgaaaa ggagagataa acatgatatt tgattctcat
    13981 acccatttaa atgctgaaca gttcaatgaa gatattccag aaacgattca gcgagcacaa
    14041 gaaatggggg taacgaaaat ggcggtcgtg ggcttcgata cgccaacgat tgaaaagtct
    14101 ttgcaattaa gccatgacta tccaaatata tacagtatta tcggctggca tccgacagag
    14161 gctggcagtt atacgaaaga aatcgaaaat aaattacaag aacaattgac tttaccaaag
    14221 gttgtagcat taggggaaat tggcttggat tatcattgga tggaagaccc gaaagaagtc
    14281 caagataaag tatttcgcag acagattgct atcgcaaaag aaatgaacct accaatcagt
    14341 attcatacta gagaagcact tgaagacacg tatcaaatcc taaaagaaga agatgttcga
    14401 gatatcggtg gaatcatgca tagtttcagt ggtgattatg aatgggcaaa acgatttctt
    14461 gacttaggga tgcatatttc atttagcggt gtcgtcactt tcaaaaaagc attagacgtc
    14521 caagaggctg cagcaaatgt accaatcgaa cgattacttg tggaaacaga tgccccttat
    14581 ctggcaccag ttccttttag aggaaagcga aatgaaccag gctatactcg ttatacagta
    14641 gaaaagattg ctgaacttcg gaatcttccg acagaagaag tggctgccca aacatggaca
    14701 aatgcgcacc gattatttgg tctaagcgaa catggataag atgaagatcc aagagattat
    14761 agtcgttgaa ggaaaagacg atacaagaag gctgcgggaa gtagttgatg cagatacgat
    14821 agaaacaata gggtctgcaa tcaatgaaga gatcctgatg caaattgaac atgcccaaga
    14881 gactcgtgga gtgatcgttt ttaccgatcc tgatttttca ggagaaaaaa taagaaaaat
    14941 cattatggaa gctgttcctc aggcaaaaca tgcttttttg ccgcgcacac aagctaaacc
    15001 aaagaaaaag ggaagccttg gtgtcgagca tgcaagtgat gctgctattt tagaagcatt
    15061 gaaaaaggtc gtgacgccag acatttccca aacggctgtt tctgaaatca ctagacaaga
    15121 ccttttagac tatggtttaa tagctggggc acaagcaaaa gaaaaacgag aaaaactagg
    15181 tgacgagttg cgcatcggtt acacgaacgg caaacaattg gaaaaacgtt tgaagatgtt
    15241 tcgtattacg ccgaaagaac tcgcccaagc aatgaaaata gtggaggaac aacatgagtg
    15301 aatatcgtga aattgcgaca ccctctagaa caaaagagat tttattgaaa catggttttt
    15361 catttaaaaa aagtttagga caaaattttc tgactgaacc aaatatttta aggaaaatcg
    15421 tagaaactgc gcaaatagat gaacatacga acgtgatcga agttggacca ggaatcggtg
    15481 cattgacgga acaattagcc aagcatgcaa aacaagtcgt agcatttgag atcgatgatc
    15541 gtttgatccc tgtattggct gatacgatgc aaccctatga caatgtgact attgtacatc
    15601 aagatatttt aaagaccgat ttgtcaacag ctgttagaga aacatttcat gaggagcttc
    15661 cgttaaaagt cgtagcgaat ttaccttact atattacgac accgatcatg atgcattttc
    15721 ttgaatcaga tttggttgtg gatgaactag tcgtcatgat gcaaaaagaa gtagctgatc
    15781 gtatctctgc tgaaccagga acgaaagctt atggttcatt atcgattgct gttcaatatt
    15841 atatggaagc cagtttagca ttcatcgtac caaaaacagt atttgtccct cagccaaatg
    15901 tagattcagc gattttgaaa ctgacaagaa gagatatacc ggcagtcgaa gtgacagacg
    15961 aaaaagcatt tttccgattg acaaaagcgg catttcagca aagaagaaaa acgctttgga
    16021 ataacttgca gcattcgtat ggcaaagatg accagacaaa agcatggtta gcaaaaagct
    16081 tggaaacagc tggaatcgat ccaaaacgtc gtggggagac tttgtcatta caagaattcg
    16141 ccgcattaag caatgcgatg tcagaaaata tgcagtaaaa aaagaggttg tgacagaagt
    16201 tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca aacaaaaata gttcctcatg
    16261 tttttcgttt gtttgggctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    16321 aggttgtggg cctgccgttt aactctaagt cacaaggaac aatttcaaaa aacagcttct
    16381 catgtttttg agttagttgg tcttattact tgatgcaagc ttttgaccac tattatgccg
    16441 aacaaggaga tgtgacacaa attttgtcac atctcctatt tttgtttctt gatcaaaaaa
    16501 ttcttatact tgatactcac actcattttg tatggattta gaaaagaata tgtgtcttga
    16561 cagttattag taagtgagtt atactaagtc gacatttatg tgtcaagaca tattaggaga
    16621 gagaaaaaat gagaaaaaat tcagttcgaa aactaacgat ttctgcttta ttgattggga
    16681 tgggggtcat tatcccaatg gtcatgccta aaatcatgat tccaccagct tcctttactt
    16741 tggcgtctca tgtgccatta tttattgcga tgttttttac accaggagtt gcagtggctg
    16801 ttgcgctagg tacgacattt ggtttctttt taacaacgcc ggttatcatc gcattgcgag
    16861 cattgtcaca tcttgtgttt gcgttgattg gggcttggta cttgcaaaag catccgagta
    16921 tcgttttaaa aaatggacag tttacttttg ctaattggcg tttccaaggg ttcaattttg
    16981 tgatcggtgt gattcattct ttagcagaaa tgctagtagt cagcatcttt tactttattg
    17041 gtaatatgcc tgaaacatat tattctcaag gatattttta tacagtattc atcttgatgg
    17101 ggattggtgg gcttatccac agtttagttg attataatat tgcttatttt atagcaggaa
    17161 cactcagcaa atattttgat atccccgtat ttacggcagc aaaaaaagaa aatcggaaag
    17221 agtcgattca agggtacgcg aagaaaacga catattagac atgatctctc aaaaaaaaaa
    17281 ctctcatcta gtaatggata ataaatcctc taagatgaga gttttttgtc ctaaaaagag
    17341 ctgcaccaac atcttctggc acagctctaa cagggggcaa tttatggaag tttgatgact
    17401 tgttctgttt ctttatcaaa gaagtggcct ttgctgatgt tgaaggcaag gtcgactatt
    17461 tcgcctggtt tatggaaatc tcttgcatct acttttgaga tgaactcagt agaaccagtt
    17521 tttgtgtaaa gcatcgtttc agctccaagt aattcggaaa cgacaacttc tgatttcact
    17581 acggcttcag gtgaagcttc aagggctact tgttcactgt ggatgtcttc tggacgaata
    17641 ccgaagataa cttcttttcc ttcataacct ttttcaacta atactttgtt ttttccttca
    17701 ggaatacgaa gcttaagccc atgtccatct gtgataacac catttttcaa tgtcacatta
    17761 aagaagttca tggcaggaga tccaataaag ccggcaacga acatattgac gggtgtatca
    17821 taaacttctt tcggtgtacc gatttgttgg ataaatccgt ctttcatgat aacgattcgg
    17881 tcagccatag tcattgcttc tgtctgatcg tgagtaacat agatggtcgt tgtttcaaga
    17941 cgctggtgaa gtttggcaat ctcagcacgc atggctacac gtaatttagc atctaaattt
    18001 gataatggct catccattaa gaagactttt gcatcccgaa cgattgcccg tcccaatgcc
    18061 acacgttggc gttgtccacc agataaagca gctggttttc gtttcaagta ttctgtcaga
    18121 cctaagatct ctgctgcatt gtccacacgt tttttgatgt ctgctttatc atatttacgt
    18181 aatttcaagc caaaagccat attatcaaaa acagtcatat gaggatacaa tgcgtagttt
    18241 tggaaaacca tggcaatatc acggtcttta ggtgccacgt cattcatgac ttttccgccg
    18301 atatttagtt ctccttcaga gatatcttcc agtcccgcga tcattcgcaa agtagttgac
    18361 tttccacaac cggaaggacc aacaaaaacg ataaattcac ggtctttgat tgatagatta
    18421 aaatcagtta cagaataatt ttctgcattg tcatattttt tatatacgtt tttcagagcc
    18481 atttctacca taatacgttc cacactttct tttttagttt tattaactat ttaaagtata
    18541 aatgaaagcg ttaactaact tcaatgtcat gttgaacaag aattttttct tttttttgtc
    18601 aatgtgctag ttttaagctt taataaatat ccataagaaa taaaaactga tacactggag
    18661 taaataagta tgttaacaat atcaaaagga gtgtctctta tgaaaatcgc tttgatcgct
    18721 catgaccgaa aaaaacctat gatggtgaaa ttagcaacag cgtataaaac aatattggaa
    18781 aaacatgaac tttttgctac cgggacgact gggcagagga tcacggaagc aaccggcttg
    18841 ccgatccatc ggtttaaatc cggaccgtta ggcggggatc agcaaattgg agccatgatt
    18901 tcggaggatc agttagattt ggtgattttt cttcgagacc cgctggctgc acagccccat
    18961 gaaccagatg taacagcact tatccgttta tctgatgtct atgagattcc gttagctacg
    19021 aatatcggaa cagctgaggt gctactaaga ggactggaag ccggcttcct agattttcga
    19081 agaatcgtcc atgaaataga caagcatcca ctttcatttt gatggataag cgtatggaaa
    19141 aataacgttt aatgttcgcc tatatgtagc tataaaagct aaacaaactg ataatatgcg
    19201 atataatacg aacgtattgg ataatataaa caataatatt agtttttcgt atttgcagta
    19261 aatgtgaaaa tatgctatag tttctgtggg aaaagatccc aaaaataata cagagtagaa
    19321 aataaagcgt taagtgctaa gaggatggga tgttgcctct tggacgaagg acgtaatgtt
    19381 cgcggtttta ttttcgcatt cgctgcatga tacgatgtag cagctcttaa aggagatgct
    19441 aaaaatgaag aaacaccggt tagacgcacg tatgattgct attatgggct tattgattgc
    19501 attgatggtc actttgtccc gactggtagc aatcgagacc ccatttatta aaatcagtgt
    19561 cacatttatt ccacaagtga tcatgggcat tctttttggt cctttttggt cagggatagg
    19621 cgcagtttta gctgatttag taggaatggc cctcttctcg aaatctgcat tctttattgg
    19681 atttacattg aatgcattta ttgaaggagc aatctacgga ttctttttct atcgaaaaga
    19741 gatcacttgg aaaaatgcca ttctggctac gcttagtgtc acgctgatca tcaacttatt
    19801 tttgacacca ttatggcttg cgttgatgta ccatgtgcca ttgttcagct gggtcgtttg
    19861 ggcgccccgc ctgttaaaaa cagtaatatg gttaccgatt caatcaattg ccatttatta
    19921 cgtaggacgt agtattcctt acaaaaaaat tttaagaagt ttagcgatcc acgctaaata
    19981 aaaaacaagc agtcttccca tcccagaaga ctgcttgttt ttattgtgct gtgaattgtg
    20041 cttgatagag ccgtcggtaa taaccatctt tttgaagcag ctcatcatgg gtgcccattt
    20101 cgacaatagc tccctgatcc atcactaata tctggtccgc atttttgatt gtggacaggc
    20161 gatgggcaat cacaaaactg gtttttcctt ccatcattgc taagaaggct tgttggattt
    20221 ttttctctgt caatgtatcg actgagctgg tagcttcatc taagatcaac atagggggat
    20281 tactgatcat cgttcgagca atcgtcaaca gttggcgttg tccatctgat atctttaacc
    20341 cttgaccgcc aatcttagta tctaattttt ccggcaaacg ttctacaaat tcatacatat
    20401 aagaggcttt tagggcatca ttgatttctg cgtcacttgc ttccggattc ccaaaacgaa
    20461 gattttctcg caatgtactg tcaaatagcc aagtatcttg taacaccatt ccaaaacttt
    20521 tacgtaatgt atcacgttgg atagagcgga tgtcatggtc atcgactgta attgttcctt
    20581 ttgttgtgtc ataaaaacgc atcagcaaat taacaagtgt ggattttccg gcccctgttt
    20641 ttcctactat agcaatggtt tgacctggat aagcagtaaa attgaaatct tcgatcaaac
    20701 gctgcttggg gtcataagaa aaagaaaaat gatcaaaaga gacttttcct ttgatatttt
    20761 tgggttccaa ggcataggca tctggcaaat caggcttttc ttctggctga tcgatcaaat
    20821 caaatgctcg ttctagacca gaaaaagcgg tttgcagttg tgtcgtgatt ccagaaagtt
    20881 cgataaatgg tttagaaaac tgacttgagt agatcgtaaa gctggaaatc acaccaacag
    20941 tgattgacga accactcttc aatgccaata ggccgccaac taaaccaatc gataaataag
    21001 caaggtgatc tacaaaacga gaagacgggt ttgtcaagga agaagaaaat tgtgcccgtt
    21061 gtcctttttc atatagatca gcatttagca gttcaaattg ctgttgacta gcttcttctt
    21121 gctgaaaagc tttcacgatt ttctggttac cgattcgttc ggtcacaaag cccgagatat
    21181 ccccaataat cctttgctgt ctatcgaaat ttgtttgtga agcacgagca acgatccaac
    21241 tcacaaggaa aataattggt gtagaacaaa gaacgaccaa tgtcagaagt ggacttagac
    21301 gcatcataaa aataaacgaa agaatgatga ttgccactcc agaaaataat tgattgaagg
    21361 ccgcagaaat tgcaatggaa atattgtcca tatcatttgt aaatcgactg acgatatttc
    21421 cgtgggagtt ttgatcataa taacgaagtg gcaatcgatt cagatgagca aatgcatctt
    21481 ttcttaattt tgcaacggat aagtaagcta accgattgct taacacttgg atgagccatt
    21541 gactgactac gttgattaaa acgataccac cgaatagaat aagtaaatgg aacagtcgat
    21601 tgaagcggac ctgtccttct ccaatcattt gatcgatact ttgaccaatt tgtaacgtca
    21661 tcacaactgt tgcaatccca ttgatgattc ctagtatcac agctagccaa atgtcttttg
    21721 cataggcagt aaggtaagga atgaatcggc gaagcgtctg caaggataat ttttttactt
    21781 tcataactat tcttcctcct gtgatgcgac gatttcctga tattctgctg attgagcaag
    21841 taattcttca tgggtaccct gagcagcaat cttaccttga tccatcacta agatatgatg
    21901 tgcttcttga atagagcgga cacgttggga gataataatc actgtactgc caagataagt
    21961 ctgtagcgcc ttacgcaaat ccaagtctgt ttgataatcc aacgcactta aagagtcatc
    22021 taaaatcagt aatgctggct tggcaatcaa agctcttgca atcgtcagtc gctgtttttg
    22081 tccgccagag aaatttttcc cattttccat gacttttgta tctaaaccat ttggaagctg
    22141 acggacaaat tcttctgcct gagcgatttt cagagcttcc caacattctt tttctgtggc
    22201 gtctttctta ccccattgaa ggttttcacg aatagtcccg gtaaatagta cagaagtttg
    22261 gggaacaaga gcaatttgct gacggagatg atccagctgc caagaacgaa catccattcc
    22321 gtccattata actgtaccgg aactgacatc atagaaacgc ggaatcaatt gtgtcaaagt
    22381 cgttttcccg cttccggttg gaccaatgat tccaaggact gtatttcgct tcagctgaaa
    22441 tgtaatattt tggagagaaa gaccagaatc aggagtataa cggaagtcaa catggtcaaa
    22501 agcgataatt gcttcagaag aaaaatcggg agtagtactg acctcagctt caagaatcga
    22561 attttctgtg tctagcacct ctttcacccg atttcctgaa gcttcggcac gtgtgaagat
    22621 cacgacgagg tttgaaacaa cgatcagtgc caaaagcatt tgattcatat aattgatcaa
    22681 agcaagaact tgtccttgtt gcaagctacc aatatttact ttgatcccgc caactgtcag
    22741 caaacagatg atcccgacat tcatgatcaa ggttgtagca ggtgataata gggcagagat
    22801 attggaaaca cgtaaataat tgttcgctag atcatttgtg cttttatcga acttctctgt
    22861 ttcttttttt gtctgcgcaa atgcgcggat gacacgaaca ccgctaagat tctgactaac
    22921 gtgttcattg agctgatcta gtttttcttg cactttttgg tagagaggaa cggttttttt
    22981 gatgataaaa aataaaatga ttgagaaaat aggcaataat gctaagaaaa acagacctac
    23041 ttcccagtcg atcacaaaag ccatgaccac tgacccgata cttaaaaacg gtgctctgat
    23101 caataaacga atgaccattg ctaaagctag ctgaagctga ttgatgtcgt ttgtcattcg
    23161 ggtgatcaag gtatctgttc caaaatgatt caactcgttg tgagagaaag tattgatttt
    23221 tttgattagc tgattacgta actctgtacc aaatccttgt gaagctactg aagcatagta
    23281 ttggcaaatg atagcacaaa tcagaccaat cacagacata gcgaccatcc ataagcccat
    23341 ttcaatgatt tttcctcggt cattcatttt tagtccatta tcgatcaagg aagccatcat
    23401 taaaggcagg acaagttcga agacagcttc aagaaatttg aagaacgggc ccaaaatgat
    23461 ttgcttacga tagtcttttg cataacgtaa taactgaatc atatgattcc tcctattatt
    23521 tatttgtcca caattgaaaa aacaagtact accacattgt agcttaggaa atttagaatg
    23581 aaaagagaac aagccttttc ataaatgaaa gttttattat gaagaagctt tagaaattga
    23641 atagactatt ttttttaaa
//
LOCUS       DACGMI010000046        22762 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.047, whole genome shotgun sequence.
ACCESSION   DACGMI010000046 DACGMI010000000
VERSION     DACGMI010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.047"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(44..1693)
                     /locus_tag="IXT46_002017"
     CDS             complement(44..1693)
                     /locus_tag="IXT46_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAQ4947920.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(1810..4413)
                     /locus_tag="IXT46_002018"
     CDS             complement(1810..4413)
                     /locus_tag="IXT46_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAQ4947921.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(4425..5474)
                     /locus_tag="IXT46_002019"
     CDS             complement(4425..5474)
                     /locus_tag="IXT46_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HAQ4947922.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(5500..5814)
                     /locus_tag="IXT46_002020"
     CDS             complement(5500..5814)
                     /locus_tag="IXT46_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HAQ4947923.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(5830..6276)
                     /locus_tag="IXT46_002021"
     CDS             complement(5830..6276)
                     /locus_tag="IXT46_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAQ4947924.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(6277..8253)
                     /locus_tag="IXT46_002022"
     CDS             complement(6277..8253)
                     /locus_tag="IXT46_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAQ4947925.1"
                     /translation="MKIEIIIVHLSCIQEVKIMGIEFSERQMKILYFLIENEHTTYKE
                     LSEQLYVSTKTISKDILILKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKIN
                     IADSPEDRLTYVFAKLLNTNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLV
                     SDRNGVRIKADEKSKRRLMSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDI
                     LKKVAELLNRYMNKTQLKFTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNT
                     LILIKMIEKAFSIIVPIDEQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVR
                     IKLNEFYPDEELINNLVLHLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEE
                     IEERFCIHFNEDEIAYVTLHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFA
                     DMVEIEDVLSINELQDRKVTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQL
                     NEQTEDAFLNLLDKRFCFFTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKL
                     SSTAMNDFAMPHIEVDFIKKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKI
                     YETFNEIASNHELLANLKTSSSFEKLVYILKEGL"
     gene            complement(8411..9307)
                     /locus_tag="IXT46_002023"
     CDS             complement(8411..9307)
                     /locus_tag="IXT46_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4947926.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(9300..9980)
                     /locus_tag="IXT46_002024"
     CDS             complement(9300..9980)
                     /locus_tag="IXT46_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4947927.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(9981..10763)
                     /locus_tag="IXT46_002025"
     CDS             complement(9981..10763)
                     /locus_tag="IXT46_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4947928.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(10756..11673)
                     /locus_tag="IXT46_002026"
     CDS             complement(10756..11673)
                     /locus_tag="IXT46_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4947929.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(11837..12160)
                     /locus_tag="IXT46_002027"
     CDS             complement(11837..12160)
                     /locus_tag="IXT46_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4947930.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            12948..16175
                     /gene="fss3"
                     /locus_tag="IXT46_002028"
     CDS             12948..16175
                     /gene="fss3"
                     /locus_tag="IXT46_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAQ4947931.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            16288..16602
                     /locus_tag="IXT46_002029"
     CDS             16288..16602
                     /locus_tag="IXT46_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4947932.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            16615..16989
                     /locus_tag="IXT46_002030"
     CDS             16615..16989
                     /locus_tag="IXT46_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4947933.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            16999..17334
                     /locus_tag="IXT46_002031"
     CDS             16999..17334
                     /locus_tag="IXT46_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAQ4947934.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            17417..18757
                     /locus_tag="IXT46_002032"
     CDS             17417..18757
                     /locus_tag="IXT46_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAQ4947935.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            18835..19509
                     /locus_tag="IXT46_002033"
     CDS             18835..19509
                     /locus_tag="IXT46_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4947936.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            19742..20176
                     /gene="dcm"
                     /locus_tag="IXT46_002034"
     CDS             19742..20176
                     /gene="dcm"
                     /locus_tag="IXT46_002034"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAQ4947937.1"
                     /translation="MRFLDLFAGIGGFRLGMEQASHHCIGFCEIDKFARRSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQRFSDTRGTLFFEIARF
                     TTLLRPKLLFLENVRGLLNHEGGATFETILRTLDGLGYDVEW"
     gene            20177..20884
                     /locus_tag="IXT46_002035"
     CDS             20177..20884
                     /locus_tag="IXT46_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAQ4947938.1"
                     /translation="MLNSKAYIPQSRERIFLIGHSRDACTEQVFPIIGPSSTSDQNIR
                     NLVNINPSNRGMGGQVYGSDGVAPTLTGDEGIKIALPARDGISVAGLLPGKFEQGNRV
                     YEVTGTAPTLSTKQGGTKIMIRKNETEYQEVKPEDSVNLAFPNSTSRRGRLGKQSVHT
                     LLTGDQQAIVTDQYQIRKLTPRECWRLQGFPDWAFDRDSQVNSDSQLYKQAGNSVTVP
                     VIFDIARRLKELDVHGL"
     gene            20874..21164
                     /locus_tag="IXT46_002036"
     CDS             20874..21164
                     /locus_tag="IXT46_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947939.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARMELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            21420..22604
                     /locus_tag="IXT46_002037"
     CDS             21420..22604
                     /locus_tag="IXT46_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4947940.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            22619..22738
                     /locus_tag="IXT46_002038"
     CDS             22619..22738
                     /locus_tag="IXT46_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAQ4947941.1"
                     /translation="MEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKGK"
BASE COUNT         7075 a         4313 c         4262 g         7112 t
ORIGIN      
        1 aagccaagat ttttgatcca ataaatactt tcgatcactt cgcctatccc aatacatgcc
       61 actgccgctt ttcatcaaat aacgcggctt ccgtttttgc ggtttctact aaagtctctg
      121 ggtaatccaa aactttcagc aaggcaatcg catttcgggt ccttgaaggt ccttctttta
      181 atttgaaatc aaaactgatt ccttttcctt ctgttacttg ttcttcaaag tggacattct
      241 cacaataatt ctttaaaatc tctgtcaatt cgatatcatg tgtggcgaca aatgctaaag
      301 atggatactc cgcaagccac cgaacgactg aagcggaaga agcaatccgt tcgatcgtat
      361 ttgtcccttt taaaatctca tctacgaagc agtagcagcg ttctttggaa gccacttggt
      421 ccaacaaacg tttgatcgat ttgatttctg aaacaaaata actgtcgcct tcaaataaat
      481 catcttcgat tgccatggaa gtcaacacat gtccaggttg cagggtaaac tgttctgcaa
      541 tcgctgtttg gatcgtctgt gctagaatac agctgatggc tatacttttg acatacgtag
      601 attttcctga tgcattggaa cccgtgacta atgtattctt ctgccagttg accggattca
      661 ctaccgcttc ttttaacaat ggatgataga tatctttcgc tgtcacaccg ccctcagtaa
      721 actctggtcg gcaagtgatg ggcatataag tacggtaatt caatattgca gcggctactt
      781 ctaattctcc cagcaattcc cacagcttga tggcttcagt tgaatgcttt tctaatttag
      841 tgagaacgaa atgataggag ataaatggca gcatgaacat gatgttgaca tattcaaaaa
      901 tcaactctgc ttcactccca ctcttcatac gaaatgaaaa acctaattta gggatgtctc
      961 ttaatggttt agtttgctgt ttcagctctt cttgaagtgg tgtcggcagt tttgctagct
     1021 gattggcggc tgaaatcgtt gaaaccaaat aactcatgct attcagctct gtttctagtg
     1081 tttgtttctt cactagataa tagaccgtat tgaatactaa cccaccgatt gccaaataga
     1141 ttcctagtac ttgtcctaaa agaagcaaac ccaaacccac cagcggaagc aagccaagaa
     1201 aaataaataa acctacgcgt ccaatctttt tactttttcc atccgctaga tattgttttg
     1261 caaaattatg atcttttttt cctaaacgag cgaattgata ttggattttt tctctcagtt
     1321 gaggattttc ctgataaaaa gcaatcagtt tttctaactg ctgatcttca ccaaaatcaa
     1381 agctgcgtaa acgttgatac aacgcttctg aacctacact agaataggta ctgttgattc
     1441 cttcgaatac ttcgaacata tccaggtcat accaagtaag atcatcgatt tcgctatccc
     1501 atgaacggaa cttcttctcc gtgagccatg cttccttcaa gctttcttct ttatcaaatc
     1561 tcggttgata aggaattttt tcccatttgc tacgaactgt ttcctttaat ttcaaacgtg
     1621 aaaaaatgtc taaagcaact aataaaataa cagctgcaat aataattaaa acgataaatt
     1681 ctctttgacc catatccctc tccgttcctt tatttgttag ctttagtata gcactgttgc
     1741 gctatttgaa aagagggtaa aaaaacacct ttcaaaataa aaggtgtttt tttcttgtat
     1801 attacatatt tatctctcat ttatcaaaat tgacaaataa tcatagggag gaattgttgt
     1861 taattcttgt ttattctcca gtgcattgac aactgtccca agggaaagga tagcctcagg
     1921 tactattttt tcttgttctg ttggattagc taagcgaaga acaaatcctt gttcatgaaa
     1981 ataagaagga taaatcgatg atacaattaa gtcttcaggt aattcaatca atgaaaattt
     2041 acgaggaaca tcaagttcat tttgtaatgg ccaaatcttg ttatctaacc tgtgaataaa
     2101 tacattcagt ttctgctttt gataagaaat agattgttct aaccgttttt ctgcctgttt
     2161 tgccactttg aactcattaa atcttccttc ttctacatta aatccaaaag tgactttata
     2221 ctcacctatc tcttgagcta gcggtgtttc catcatgaca tgcccttcat ttgtcgtatc
     2281 tcctgaagct cgcccaggtc gccaagcaag attaggtttt ccaagttccc ctgttgttga
     2341 aaataaggtt atgattaatt gattttctat acgttcatac tcttttaaac catctgcata
     2401 aaacgtaaaa taatgatcat tttctgccac agagacactc ttatcgaata tttctaaatt
     2461 aacaggtttc tctaccatag tttctgacca attcggagga atgacatcag gggtattttc
     2521 aataaatccg ttttgaattt gtgcaattga tttttcagat ttatctaaaa cattaattgc
     2581 taagcgcata cgatgcgagt aaacagtatt atgaattttg agtgtgcctt caacgatttg
     2641 actttctccc agactgaacg atatttcata agatatttct tccatttcgg gtttttcaga
     2701 taaacgatct tttaaatctt taggaagttg agcttttccg taaacaacta atgtttcttg
     2761 taaagaatct ttatatactt tagctgtttc taattttaga gatagttctg tatctccttc
     2821 taatggtgaa taatcatacg tatcgccatc atttgctgaa tcgatcaaat gaacgaaatc
     2881 aagatattgt ctatctccaa ctatcaaatt caattgccca tctttaaaag aaagtttata
     2941 tttattgtta cttatctcag ttttgtctat ctcgattgct gtttctaatt tttcattatt
     3001 tttctcaaat tcaacaacag tgtatcctag tgctggcaca tttacattta tttttatgtc
     3061 aagttcataa taagctggtt catcaaaata ttcgaaacct gtagcaatca tccgataagc
     3121 atttttccgt tctggaaaat aaacttcttt ttcaatgata ttatagggac tacctttgaa
     3181 gtgtattttc tttgaatcag ctactacatg cacgattttc gatccactat aattctcagt
     3241 cgttgtgttg aaaacaagga cttcattcga ttttagcttt aatgcatcag ccatccgttt
     3301 tacaataagg ttttcgattc cgtcagctat ctcattagct tctttgattc gatggaaaat
     3361 atcttccgca acattatctg aaacacagcc accaatacta tcatgagcct ggttttgcaa
     3421 aatctttttc cataaccgac gaagtaggcc tttactgata tggataccat ttctttctgc
     3481 aatcagcatg agcggctcaa ctcgttttag aattttttgt tccaatttaa aattttctat
     3541 tttcattttt gttcttactg agccaataga acgatgaaca cgagagtaaa ccggctgacg
     3601 aagttcacct ttatattcag gtaattcttt tttgtttctg ataacttcta cataagaagg
     3661 ataatctgaa ataatattgt ggaatttact gtatttattc aacttctcta cgacttgatc
     3721 aaaatttaaa atcattgact tttgatctac acccgaaggt actaaaatat ctttgttttt
     3781 tccttgcata tgaagcattt caactgcttc atccaacttt tcttttgcaa attcaggaat
     3841 atctttaatt gcgtctaagg tcatcattcc agtcatataa ccaaatggaa aattcatggc
     3901 ataaacaaat ttatctccca atcctttcca gataaaataa ggagatggaa ccatcgtttc
     3961 aaagtttaat cctcgccaac acatgaaatt atcgatttct acttgatgca aaagtgtagg
     4021 caaattcgca ttgaacccaa acgtgtcagg caaataccct accatcattg gatctccata
     4081 tttaaggatc gtatcactga ttccaatcat taagtttctt aaaattgatt cagcatccac
     4141 taataaggca tctgtttgtg cataccacgg tcccacgaat agttgtcctg ttttcatcag
     4201 tcgttggata accttaagct tttgcggatt gatctccaaa tactcatcga cgattgaagt
     4261 ttgtccatct aaacaaaagt ttactttagg gttcctttcc aattcatcta gaacttcagt
     4321 aaagacctga tcagacaata cgatggcatc ttcatttgta aaataccatt ctctgtccca
     4381 gtgcgtgtgt tgaattatat gtgcatttac catatcagat tctcctactt tccttcttct
     4441 actgaattta cttgttgttc ttttttatac ttgatggatt ttagtgcatt gaccattaac
     4501 gctgtaacca ctcccccaat aacaattgat actaaatata aaggtatatt cgtaacaaaa
     4561 ggaattgcca taaaggttga aagcattgtt tcttgagtaa caccaaaaaa tccatttaga
     4621 ccacatgcta ctgcagtgcc caccacgatg cttggtatta ctcgtaaagg atctttcacg
     4681 gcaaacggga tcgtcccttc agtaatcccc acaaggccca taatcatagc tgtctttgca
     4741 ttatctcgtt ccgattcatc ataaagtttt ttgtttaaaa ttgttgctaa aaacattcca
     4801 aatggcggaa tagcaattcc taataacatg gctgtactag gtccaaagct tccgcttgaa
     4861 aaagaagcaa ccccaaaagc atatgcgatt ttattgatag gtcctcccat atcaaacgcc
     4921 atcattcctc ctaaaatagc cgacatcaaa gcagcatttg ctcctgacat gccttctagc
     4981 caattagtca gtcctgttgt cattgcttga ataggcgtag ctagtacata ccataatatg
     5041 attccaacaa ctaatgtagt aacaaaagga atcagcataa ttgattttag actaataact
     5101 tgcatcggta cttttacttt tttcaatgca ttagctaaat agccacaagc taatccagca
     5161 accattcctc caataaatcc cataccaaga ttttgacaca tcatcccagt gataaaagct
     5221 ggtgctagac cgggacggtc agcaattgaa tatgcgatat aggctgaaat catcggtacg
     5281 ataaactgta atcccgtctg accaatcatt cgcaggactc cccagaatgt atccgtctgg
     5341 tcccaaacac ctgtgccacc aaaaatgact gcaatagaag ttagtaaccc tgctgctacg
     5401 acaagcggga tcatatagga aaccccactt tggaaatgat ttagaatttc tcttccttgt
     5461 ttcttgaatt ccattagtaa ctcccccacg atatattttt tatttgttaa ttaatgcaat
     5521 tgcttcatca atcgtctctt caccatcttt tactacctct gaggtcccta ctgttaaaat
     5581 cggtttaccg tcaaagcgac ctcgttctga aacatttgta tctactgcaa atatgacaac
     5641 atctgcctcg gaaacatccg aaattgaaag tttgttttct atccccatag ccccctgtgt
     5701 ttctacttta atatctaacc ctttcttctt cgcaaacttt tctaaattag cttttgccat
     5761 ataagtatgg gcaatccctg cgatacatgc tgttactgct actatttttg tcatatgaaa
     5821 ttcctccttt taaaatgata gagcttttac caattctttt ttatttctcg aatcttttat
     5881 tcttttaaca aactcgtcat ccatcaatct tccagataat tctgctaaaa tacgtaaatg
     5941 attagtacct ttatcagtgt cttttattgc taacaaaaag acgagatcaa ctggttgatc
     6001 atctaatgcg ccccattcaa cagaccgctt taacttggct acagccactg ttgattcaat
     6061 tactgctagg cttttgccat gaggaatggc gatatttttc ccaattcctg tggtcatatg
     6121 gttttctctg tcaaatacgt ctttttgaaa ttgtttgtgg tcagacacaa acccattagt
     6181 ctctaacaat ttcgataatt tttcgactac acttttttta tcagatgcat ttaaatctat
     6241 cactatatta tttatattga ttttttcact gatcatttat aagccttctt tcaatatata
     6301 aactaatttt tcaaacgacg aactcgtttt taaatttgct aataactcat gattcgaagc
     6361 gatttcattg aatgtttcat aaattttatt caattcaggt tttacttttt cattaagtgc
     6421 aaaaaagaaa acagaatgaa caagtgtccc atcccaatca attccttctg gattaacgta
     6481 gacacagatt actggctttt ttataaaatc tacttcgata tgcggcatag caaaatcatt
     6541 catcgctgtt gaagatagtt tttctctttt gattgctccc tctagtatcc cttctttcgc
     6601 gtaattttct tttaccaatt ttttggtaat tatatttaaa acgttcactt gattatcctt
     6661 tatttggtgg gtaaaaaagc aaaatcgttt atctaataaa tttagaaaag catcttctgt
     6721 ttgttcattt aactgtagat actgttttac ttttctgaca tctgccccta acatcaaagg
     6781 actaacaaca ataacaggaa aatttgtatt ttcaatcgga atcgtgctta taacaagttc
     6841 atcagtgact tttctatctt gtagttcatt gatgcttagt acatcttcta tctcaaccat
     6901 atctgcaaaa ccgttattta ttctttgctc taataatttt gatgttccat atccgctact
     6961 acaaactaat atcactttcg ttttgtcagg tttgtaacga tccaaaagtg attgaatatg
     7021 gagtgttacg taagcgattt catcttcatt aaaatgtata cagaatctct cttcgatttc
     7081 ctctaataaa tctacactta tcataaatga ccttttaaaa gaatatttga ttttgtccgt
     7141 ataagggtta tagatattta ctcccaattt gagtctttta actgctgcat tgagatgtaa
     7201 tactagatta ttgatcaatt cttcatcagg ataaaattca tttaatttaa ttcttactaa
     7261 ctcttgtagc tcaacaccca tatctaaata ggaaagcttc gtttgatcta agtcgtgatt
     7321 catagcattt ttttcaatcg aagtaatgtg aatgtcaaca taagcttgtt catctattgg
     7381 cacaataatt gaaaatgctt tttcaatcat tttgattaaa ataagtgtat tctttgagat
     7441 ttcttcttca gaattattac tacgtgataa gaaattgctt gtttcaatcc tttctatcgc
     7501 aatagcaagg tggatagcta aagtttgaaa ttcataatct gtaaatttca attgtgtctt
     7561 attcatgtat cgattaagca attcggctac ttttttcaat atgtccttat ttaagaaatt
     7621 attcgcttca ccaatgaaat tgatattcaa gtctaagaga tctgttttac tgttagatgc
     7681 tgtaaagcca ccccaataat agttcacaac ttctgacatc aaccttcttt tacttttttc
     7741 atcagctttg atgcgcacgc catttcgatc tgaaactaag gacatcccat gcttgtttag
     7801 tctttttcta acatctttca ttgtgctttc taccgtcgac ctgctcacgt ataattcgtc
     7861 agcaagattt tgaatcttta gagaatcatt agtattcaat aatttagcaa acacataagt
     7921 tagacggtcc tccggagagt ctgcgatatt gattttatga ctggataata aatttcgaag
     7981 tgtttctttt tttccaataa gcgaaacgcc ttttttaggt tgaaccaaca tttgtacatc
     8041 tggcattttt tggattattt ctttcaaaat taaaatatct ttgctaattg ttttcgtaga
     8101 tacatataat tgttctgata attctttgta agttgtgtgc tcattttcaa tcaaaaagta
     8161 tagtattttc atttgccgtt cgctaaattc gatgcccatt atcttcacct cctgaataca
     8221 gcttaagtgt acaattatta tctctatttt catacagaag aaagttcttg attaatgtag
     8281 aagtttctaa tattcttgat tatttcaaat caataaaaaa gcctgcaata tttatatcac
     8341 aggctttttt ctctattaaa tatatataag ataatacatt tttctactag ttctcactaa
     8401 tcttgtataa ttaaaccctc cgcaacttga cggagatgga gaagatgccc ccgtctaatc
     8461 tagcggtcat ctctcctccc attccttcca ccaatttttt tgacaggtaa agcccgattc
     8521 cgctagattc cgtatttgtg cggctggtat tttcggtata aaaacgctgg aagacttttt
     8581 caacagaggt ttgcgttcct ggtttgatag gattggccac tgttaatcga atgaatggat
     8641 cctcttttga aaatgtcacc tttgcttgtc catctgcata acgcaataaa ttctgtatga
     8701 tattttgcag cactcgcagc aacatgagcg gatctgctaa tacagttgta tttatcgagt
     8761 gttcagcgaa cgctacctcg atatttttct cagaaaattg ttcataaaaa gagaaaaata
     8821 cttcttccac ctctttagaa aaagaaagcg tatggagatc catttctttt tgcttcgtct
     8881 ctattcgagc aagatcataa aactgatccg tcatactgag taatcttgca acagattgtt
     8941 tgatgatcgt taaatacttc tcccgtttct ccgtatcctc tacctgttcc agtaattgta
     9001 cataaccgtt aatagcagtc aaaggagttc tgagatcatg agaaaggccg acgatcgata
     9061 gtctgatgtt ttcttccatt tcttgaaatg cttgtccttt ttgttcattt tcatccaacc
     9121 atgtattcag tgcatctact aggtccatta gattcttttc tcgaaattcg actgaaagac
     9181 gaccaccata ttcttgtcgt tcagaaagag tggcgatttt cttagttaat ctcttgattt
     9241 ccctttgcag gaagaaaata aaacttccca taaagataac aacgagaagc aacagccatt
     9301 taatcaaatc taaaccccac tccccacacc gtatgaatat acacagcatg tgcctttgct
     9361 agcttccctc gaagattgga aatatgcata ttcactgttt tctcactatc aaaatatggt
     9421 tcttgccaaa ctgtttcata aagatttgct cgcgaaaata cttttttcgg atgttctaaa
     9481 aaaagcttca gcagatcgaa ttctcttcct gtcaaatgga cagccacacc attcacattt
     9541 acatccctcg actctttgtc cagtaagatt tccttgtaat agatgcgttg cgacagatct
     9601 tttacttgga cagaagtctg atgacgaagt tggatgccga ttcgtaacaa aagttcttcg
     9661 atatcaaatg gtttcgtcac atagtcatcc gctcctgctg ccaacaagga aactttatct
     9721 ctttgatcgc tttttgctga aagaacgatg atcggaacat tcgatgtctg tcggatttct
     9781 gctaacaatg cttcacctga aagccctgga agcatgagat ctagaaggat caaatcgaca
     9841 ggatatgtgc ttaacaataa ttttccttcc gtacctgaat aagcatcaag aagtttgtat
     9901 ctctgttcaa gaacctcctc cagtaaggaa tgaacagctt catcgtcttc gataatcaaa
     9961 atagtttcca gcaggaccac ctacttaatg tcagattttt ggaaaataaa cattcctaga
    10021 gctgatgata ccacgattgt tactagactg accagaatca ttttcggtgc ttgcgaataa
    10081 gttgcttgtt gcgcaaagtc cgtatacatg agccacgttt ccgtaaacca ctccgttaga
    10141 aattccaagc ctttgatttt tgcgaaaaca ccgggaatga aggccgttcc catgatataa
    10201 agaaaagaaa gaagcaaact gacactggta cttctagtga tgaatgtcaa agccactgga
    10261 acagataatg tccctaatgt cagcagaagc aatacaggaa atacttttag aacataattt
    10321 ccatagtttt tgattccctc aacttcacca aatccgaaag caagtgtgta agcaagcatg
    10381 gctagtcccg tgatcaaaac cacgccaagt gttgtgatca aaagcgtaac gagaagtttc
    10441 gacacataat aagtcattcg attccgtcct aaagataacg tattgcgaat cgtaccgttt
    10501 tgaaattctt ccccaatata aaagcacgca aatgctgcga aagccagaag aatccatgca
    10561 gccatttttt ctaccattaa aatccctgtt gcaccgttga tgactgtatc cgttgcttgg
    10621 tttaattcat tgccgtattt tgtatgcata taccattcgt tccaagaata aaaaagcgga
    10681 agtacgacca tcagtcctag tgagacccac attttacggc tcttccatac ttttattttt
    10741 tcagcagtta atagattaaa catgtggatt gcctccagtt aattgtaaga aataatcttc
    10801 cagtttttgc ccaactaggt gaataccatc cacaggaact tttgcttcta ccaatgcttg
    10861 attgatggct gctacttggt caattccttc aaaaagctgg ataacacggc tagattgtac
    10921 aaaataatcc ctataaccaa gagagtcgag aaccgttact gcttgttccg tcgccgaagt
    10981 gtcaattttt ataaattgac gagattcttg tgccaattct tctttcgata attctttgat
    11041 caagtgtcct tcatgcaaaa taccatagtg agtggcgatc tgtgacaatt catctagcaa
    11101 gtggctagaa agcaagacgg tgatgccccg ttcttttacc aaacgttgga tgatttctcg
    11161 catttctgcc atccctgctg gatccatccc attcgtcggt tcatccaaaa tcaaaaattc
    11221 tggattcgtg atcagtgcat ttgcaatagc taaacgctgg cgcataccta aagagaaatt
    11281 ctttgctttc tttttccctg tattttccaa tcgcatcatt ttcagcaggt cttcgatttc
    11341 tctatccgac acaccgccgt tcgctgcttg gatacgtagg ttatctcttg cagttaattc
    11401 tggataaaga gcaggggttt caatcgattg acccatacgt cgtcttgctg cctgcaaatc
    11461 cgtcgttcca aataattcga tcgaaccttc atcaatcgag atcaaaccca taatagttct
    11521 cataaaggta gacttacccg ctccattttc cccaatcaat ccatagatca ttccacgttt
    11581 gatttcgatt gatactttat ctaatgcttt ggcagcaccg tattttttgg ttataccagt
    11641 tgctttcaag accgtttcat ttccaaaatc catacttatc cttctttctt attgatgagt
    11701 gaagtatagt tgacgggtat aaagaaagca gccagaaatg tataaagaaa gtgtaaattt
    11761 tccaattgaa tgtcaaaaaa aacaatcgga caatacgtgt ctttcctatt atcaggcagt
    11821 ttgttatacg cttgtatcag tttcctgatt ctttcttttc gaccaaagtc gtttctctgt
    11881 attcctcttc actgaaaatt tttgcttctt tcagatcaag cttgagtaat tttaccagac
    11941 cggttataag gataactata gcaagactcc ctcccagaaa aattagactg tctcgcagac
    12001 gtggttgcgt tgtcttccaa tcaaagagcg caccaaacag tgctaatcca agtggactgg
    12061 ccaccatggt aatcgttgtt atcgttgaca taagacgtcc ttgtatatgc gttggaactt
    12121 ctcgctgaag ccagaccata taaaaagcaa aagaaaacat taatccttaa aaacggactt
    12181 atgaaaaata atacatgccg tttgggattt acaattagct accaaataag aggttatgac
    12241 aaaagacttt tcacaatccc ttcttccgaa taaacggtgt tctcctgcca actcctcggt
    12301 cacaagtcac aatatttatc aaacatgaga agcaattttt gtaaattcct tcttatttct
    12361 tgaagctgac cacttctgtc acaacctcag aagcggataa ataatattgt ttgatgatac
    12421 tttatctttt tcccgtttgt ttatagatcg aatgatatta tagaccaaga atcctaccta
    12481 ttaacatagc taaaaacaca aaaaaggcac tttccaaatt gtggaaagtg ccagaaaagt
    12541 taggattaag gtaactgcgc tcagcattgc ttcgcccagt acgattctcg taactcgtga
    12601 actcgaacga taatcgcaat taacgttttg agaactgtga agctttacgg gctttcttaa
    12661 gacctggttt tttcttcgta tcattgaata agtttgaaaa accttgattt ataaaggttt
    12721 tcccgtaaat atattttatt atatttgatt aaatttgaaa tgtttgtgtt ctaaaatgtg
    12781 ttctaattta aaggcagtat atttcgtatt ttagattaaa tttttaggct cattcattct
    12841 caaatccatt ctattcagtc aataaaaatt ttaaaaagac tttataaaca aagatgttca
    12901 agcgagcatc ttattttttt gtgcttaatt tgaaaggaga acatttcatg tataaaaaac
    12961 aaaaaaagaa attatgtgta ttaactattt tgagtttggc tgttcaagca attgttggag
    13021 caattgctcc tacgattact tttgctgatg aaattaccca tccacaaacg gtaaccgtag
    13081 aactagattt agcacatcaa tatgctgttg aaggaacttt tagtgatggt cgtccaatgt
    13141 cagaagtcac tgttccgcat tatgcagtgt acaacggctt taaacaagat attttctgta
    13201 ttgaaccagg agtcccgatt tacaatgagt tcactcctgg ctatgagaaa aacccgttac
    13261 cagatatgtc cgataaagcc aaattagttt ccgttttatg gaaaaaagta ggtacagatg
    13321 cagatactca tattgtggca cagaagatga tctggcaaga agttaatggg tatacccttc
    13381 actcaataaa acgatcagat ggtagtgccg taaatatcgc agccattgag gcaaaaataa
    13441 atcaagccat tgacgattat cagaagaaac caaccttcca taatagtacg gctaaaacag
    13501 tattagggca atcgactact gtgacggata cgaataatct gaatttgtca gagttcgatg
    13561 aggttgtgga aaatgccgca aacattgatt atcgtgtgaa tggtaatcag ttgataatca
    13621 ccccaaatgc caattcaaaa gaaagtggtg tgctgacgct taagaaatct gctggtaccg
    13681 gaacacctgt cgcctataaa aaggctggcc aacagacttt aatggccggg gcgattgata
    13741 aacctaatac ctacacaatc aaaattgatg tggaaacgga gggttcttta aagatcaaaa
    13801 aagtcgataa agaatcgggt gatgttgtac caggaacggt tttccattta gactttggaa
    13861 aaactttacc tgcaaaagac gtgactactg acaaagaagg cattgctaca ttggatgaga
    13921 ttcctcatgg tacaaaagta accattaccg aaaaatcagt accggcgcct tatacgattg
    13981 ataccacccc catgactacc accattaaag caggcgaaac catttacgtg acttcaaaaa
    14041 acgcacggga aaaagggcaa atcattctgg ataaaagcgg agttgaaaca gggagtgatc
    14101 tttggaatga caattattcc ttagctggta atacgtttgc cattcgcaaa gacagtccaa
    14161 ccggtgaaat cgttcaagaa atgaccacgg atgaaaacgg tcatgcggaa acaccaaaag
    14221 agattgctaa tgcgttggaa ttgggaacct attatgtgac cgaaactaaa gctagtcatg
    14281 ggttcgtgaa tacgttcaaa cctgtaaaag tcgaattgaa gtatgccaat caaaccgtag
    14341 cccttgttac cagtaacgta aaagggcaaa atcaagaagt cactggcgaa accactttga
    14401 cgaaagaaga caaagatact ggggataaag cacaaggtaa ggcagtcttt gagggtgctg
    14461 aatacacctt gtttactgct aaggatggaa aagctgttaa atggagtgag gcttttaaac
    14521 cagagttagc gaagggaacg aaaggttctg atgaaacggt cactttgact ttagacgaaa
    14581 agaaccaagt tgccgttaaa catttagcta tcaacgagta ttattggcaa gaaacaaaag
    14641 cgcccgaagg atatagcctt gatgaaacaa agtatcctgt atccatcaaa aaggtggatg
    14701 atagcgaaaa aaatgccgtg attacccgaa atgttacggc aaaagaacaa gtgattcgct
    14761 ttggctttga tttctttaaa tttgctggat cagctgcggg cactaccgaa actggcttca
    14821 atgatctgac ctttaaagtg tcgccattgg aagggaccaa tgaaatcaca ggtgccgaag
    14881 atgaagcgac cacagcttat aacgagcaat tagggtttga tggttatggc aagtttgaaa
    14941 atcttcctta tggggattat ttacttgaag aagtagaagc cccagaaggt tttcaaaaga
    15001 ttacgccatt agaaatccgt tctactttta aggaaaacaa agaagacttt gtgaagagtg
    15061 agtatgtctt taccattacc gaacaagacc aaaaacaacc aattaaaacg gtgaccgttc
    15121 cttacgagaa gctgacgaac aaagcatttt ctgttagttt gaaccgttta atgctctatg
    15181 atttgcctga ggaagaagat agtttaactt ctcttgcgac ttggaaagac ggaaacaaag
    15241 aattaacttc tctggattct accgagctag ttgataaatt gagttacaat ctacatgaaa
    15301 tcaaagaaga ctggtatgtg gtagcgcaag ccattgatgt ggatgcgaca aaagctgccc
    15361 aagaaaaaga tgaaaaagcc aaaccagtgg tgattgcaga aacaagcgca acgttggcga
    15421 acaaagagaa aacaggaact tggaaaattc agcataaatt aaccgccgaa caagttttaa
    15481 ataaaactat tgtcttattc aactatgtgt atgaaaataa ggaagctttt gaagcaggcg
    15541 ataagccagt agcgaaggat gttagcttga ataaccaagc ccaaactgtc agttgtacag
    15601 tggaacacca tgtttctatc caaacaaagg cccacctaga aaacggttct cagaccttta
    15661 ctcatggtga tgtggtggat atgtttgatg atgtgtcgat tactcatgat gtactggatg
    15721 gctcaaaaga agctttcgaa acaattctgt atgctttatt accggatggt acaaacaaag
    15781 aaatttggaa atctggcaag attgattatg aagtaaatga taaagaattc accaaaactg
    15841 tgcttgcgaa aaaagtagat accggaaaat atccagaagg aaccaagttt acttttgcgg
    15901 aaatcaatta cgataaagat gggaatatca atggaaaaca caatgaagat ttgaaagaaa
    15961 aatctcaaac cttaacacca aaagaagttc caaccatact aagtacgccg aaacaaccgg
    16021 aaacaccaac tgttccaagt ggctctcaag aatctagtcc cacagtgaag accttccctc
    16081 aaaccgggga gaaaaattcc aatgttttac tgttcattgg ttttactttg atttttgcga
    16141 cggcgggcta ttatttctgg aatcgccgga actaaggtga tgagatgata caagtaaatc
    16201 ctaagaacca acgtgcgcga ccgcctccta aaaaagtagt cgcgctattt ttgtatccaa
    16261 aactaacaat gaaaagagga aaagaagatg gaattgaaat ttgtcgtgcc agatatggct
    16321 gaaacctttg gaaagttaag ttatgccggt gaaggagaaa ttataacaga aggatatgga
    16381 cggaatacta cggtgattgg tcgcagttat catttgtatt ccagtaagca acgggccgat
    16441 gatattgagg tggtagtagc tgcggaagcc ggtgaaaagg attttgatca agaccaaccg
    16501 ctaaaagccg tgaatcccca tttggttgcc aaaggctatg agattgagaa tcgtgggttt
    16561 actgattacg tgttgtatgt tgatgattta gtgaaagcat aggaggaaaa gaagatgaga
    16621 ttaacagaag gtattgtcgt agattcaggt ttaacatttg ggaagttgcg tttttccgca
    16681 ttacgccgag aagtacggaa gcaaaatgag gatggaacaa ttggtaatga ggtaaaagaa
    16741 cgaacctata atttaaaatc ctctgcacaa gggcgaatga ttcaagttag tatcccagct
    16801 aatgtaccct tacgcgagtt tgcttatgat gcagaggtag agttggtcaa tccaatcgtg
    16861 gataccgttg ccaattatgt ttttcgagaa ggaactaccg ttaattggtt cattaaggcg
    16921 gatgatttag tcttgaagcg gcagccgaat caaggaaatc ctacgaacca aaatgaaaga
    16981 aagaaatagg tgaagattat ggaaattaat gttgaacata ttttagattg tctcgatcaa
    17041 tatggaaaag gcgagctgac tgaggaacaa ctcgttaaag cattaacctc tgatgaaaaa
    17101 atgtttctga ttatacatca aggtttactt ggagaaaata gcgacagtga agaagactct
    17161 gatgtactag actggttagg agaagaagag tctttcttta tagttgtcga agtaaatgaa
    17221 aacttatgtc ggcaggcaga atccattttg gaagaaattg gtgtggagat gccggatgct
    17281 attgaaggct ttttaaatca attggttgaa acgaaacaac tcccctcctc gtagcagtaa
    17341 atgactagca taactttttg aaattgccta atgaaatcct attgggcttt ttcgattgga
    17401 ggtggaaacc atcaaaatgt acaaaggaca tcgcatacgc gcaggagatc agcacttggt
    17461 ttatcacttt gttcttggct ggctactcgc tctgttcatc ggttggatga gcgtctttta
    17521 ttttcaagag tttagacaat ttgatatttc taagctatca ctttctacta ttgaaatcgt
    17581 ttggtctata aaagatttag tatgtctgct tggaagtctc gctttttcag gagctatgat
    17641 attgctttat attcactttt ttcttgatca ttggcgaagc ttgtggcatc gacaaaagct
    17701 agctcggatg attctagaga accattggta tgaagtgaaa caaactcaaa gtgaaggctt
    17761 tttcaaagat ttgaatagta gccgaaccag agagactatc agttacttcc ccaaaatcta
    17821 ttatcgaatg aaagatggat tactgtctat tcgcgttcaa atttcacttg ggaaatacca
    17881 agatcagctt ttaaaattgg aaaagaagtt agaaagcgga ctgtattgtg agttagtaga
    17941 aaaggaactc aaagactcct atgtggagta tactttactg tatgatatga tcgccaatcg
    18001 aattgggata gacgaagtag tggcagaaaa tgggactctg cgattgatga aaaatcaagt
    18061 atgggcttat gattctttac cccatatgtt aatcgctggt ggcacgggtg gagggaagac
    18121 ctatttcctc ctcaccatta tcgaagcact attgaagtca gatgcagaat tgtttatcct
    18181 cgatcccaaa aatgcagatt tagctgattt aggtacggtg atgcctcatg tttattcaca
    18241 aaaggaagaa atttctgctt gtgtggaaga tttctatgaa cgtatgatgg ctcgtagcaa
    18301 ggcaatgaaa gaaatgtcta actacaaaac aggagagaat tatgcctatc ttggacttcc
    18361 acccaacttt ttaatctttg atgaatacgt ggcttatatg gagatgttaa cgacgaaaga
    18421 aagtgcggtg attttgaata agctcaaaca aatcgtgatg ttgggtcgtc aatctggttt
    18481 ctttctgatt ttggcttgcc aaaggccgga tgcgaaatat ttaggagacg gaatccgcga
    18541 tcaattcaac tttcgcgtgg ctttgggtcg tatgagtgaa ctcggatatt ccatgatgtt
    18601 tggggaggtc gaaaaaaact tctttatgaa gcacatcaaa ggtcgaggtt atgtggatac
    18661 aggtggcagt gtgattagtg agttttatac gccacttgta ccaaaagggt atgatttctt
    18721 agattcaatt agtaaattag aaaagatgaa tgattgagtg atcttcaata ctgactttat
    18781 acttcaagta acgtataata cttttatata gtaggaagaa aggggataat taatatggaa
    18841 agtaatgatt cttatttaga gtatgcaaaa gcaaataagg ataagtttat ttcttatatt
    18901 atcaaaggga aatcccccga agttggacga gacgcagttt ttatggcagg gagtcctggg
    18961 gctggaaaat cagaggttgc cattggatta gctgagaatt atgataacca tgtgattatt
    19021 gatgcggatt actttcgcac ccagtttcct gattataatg gaaaaaactc tagtctcttt
    19081 caaaaagcat cttcttggtt ggtagagcag gcatttagat atgtcttaga tcatggctat
    19141 tcttttattc tggatgcaac ttttgcaata ttaagtgctg aaaaaaatat ctcgcgggcg
    19201 ttgaaaaaac attttcgagt gacgattttc tatgtttatc aagaccctaa aatcgcttgg
    19261 aaatttacac aagaacgtga aattgcagag ggacgtcatg tgccgaaaaa ggcatttatt
    19321 aacgcttttt tcaaatcaag agagaacatt gcaaaagtaa agagtaaaca tccagatgta
    19381 ttgcttcata tcataataaa agattatacg aataatattt ccgaagttca ttatgctacg
    19441 gataatctag aattattttt accactaggg tatagtagga aagatttgga ggttcaatta
    19501 catgactgag aaagaacaag taacgaaaat tgtaaagaaa tacaataaga gcattgcgga
    19561 tttatcggaa aatgctactg caaaagagtt caaaacggtg attaaatatg tagccgatca
    19621 ggccaatgaa aaacaacgga aattagttgg attaaataaa aaatagtagg acaaattaat
    19681 aatgtatgag ccaagagcaa aatgttcttg gcttttttct ttgcaatgaa tgaggtaatg
    19741 tatgagattt ttagatttat tcgccggtat tggtggcttt cgtttaggta tggaacaggc
    19801 gagccatcat tgtatcggtt tttgtgaaat tgataaattt gctagacgta gttataaagc
    19861 aattcatgat acaagtaagg aggtggaaat gcatgacatc acaagtgtat cagatgagtt
    19921 tattcaatcc ctcggaccag tggacatcct ttgcggcgga tttccgtgcc aagctttttc
    19981 aattgcggga aagcggcaaa gattttccga tactcgaggt actttattct ttgaaatcgc
    20041 tcggttcacc actcttctcc gacctaagct tttattcctt gagaacgtcc gaggattgct
    20101 caatcacgaa ggaggggcta cgttcgagac gatcctccga acgctggatg gattggggta
    20161 tgacgtggag tggtaggtgc ttaactcaaa ggcctacatt ccccaaagcc gggagcggat
    20221 attccttatc ggacattctc gagacgcatg taccgaacaa gtatttccta tcattggacc
    20281 gtcttcaaca tctgatcaaa acatcagaaa tttggtaaat atcaatcctt ccaatcgagg
    20341 aatgggggga caagtctatg gttcagatgg cgtagcgcca accttaacag gtgatgaagg
    20401 aatcaaaatc gcactgccag caagggatgg aatctctgta gcaggactat taccgggaaa
    20461 gtttgaacaa ggtaatcgag tttatgaagt tactggaacc gcccccacct tgtcaacgaa
    20521 acaaggtggt acaaaaatca tgattcgaaa aaatgaaaca gaatatcaag aggtgaagcc
    20581 agaagacagt gtgaatctgg cttttcctaa ttccacaagt cgccgaggtc gtctgggaaa
    20641 acagagtgtt cataccttac taacaggaga ccaacaagcg atcgtcacgg atcagtatca
    20701 aattcggaag ctaacaccta gagagtgttg gcgacttcag ggctttcccg attgggcttt
    20761 tgatcgagat tctcaagtca attcagatag tcagttgtat aagcaagccg gaaactctgt
    20821 aacagttccg gtcatttttg atattgccag aagattaaaa gagttggatg tacatggttt
    20881 atgatgagtt gattggagaa atttattggg tgattggaaa gattcagtca gacccagaat
    20941 tagaagaaca attgcgacgg ttaaaatttg atattcgcaa gaatggtgtc aaagtcgctg
    21001 gcgatccata tttaatgaat gaggagacgg atgctcgaat ggagctgaat caagtcatca
    21061 gtgaattgga acgaattgcg gactttgcta aagaacctga tatccgccaa tacttgtttg
    21121 agataaaagc agagttggaa attgagggta ttaccgcgga gtaacggcca aataaaccac
    21181 tgataggcac tgaccgcggg ggatttgcga agcagaaatc ctccgtggtg ctgtgcctgt
    21241 ttatggacgg cgttagccgg ccatgatgtc tcaccccccg tatctaacag gggggtacaa
    21301 aaacacaaaa aataagcaag caacgataag gaatggctgt cctatcaagg ataataagca
    21361 atttgtgtag atgttaactg atttgaaaaa gttaacacct taaatttgga ggtgagaact
    21421 tggcacaaag gaatttagat tatcggctat taaaagaccg gcgtaatgaa tatggcgttt
    21481 cacaaaataa attagctacg acttgtggac ttagtcgccc gtacttaaat cagatagaaa
    21541 atggtggcgt aaccgcatct ataaaaacca tgaggaaaat ttttgaccaa ctggaaagtt
    21601 tcaatcccga gttaccttta acgttactgt ttgactatgt aaggattcgc tttcccacaa
    21661 cggatgcacg aaaaattatt caagaaattc tccatttgaa atttgattat atgctccatg
    21721 aagattatgc cttttactcc tatcaagaac agtatgtcat gggtgatatt gtggtgatgt
    21781 tgtctcatga agaagataaa ggcgtccttt tagaattaaa gggtcgtggt tgtcggcagt
    21841 ttgaaacttt tttactcgcc caaaagcgta gctggtatga ctttttcgaa gattgtctaa
    21901 aagccggtgg cgtgatgaaa cgcttagacc tggcaatcaa tgatcgagtt ggcctgttag
    21961 atattcctga tttaacgaaa aaatgtcaga aggaagaatg tatctccttg tttcgtacct
    22021 tcaaaagcta tcgttccggg gaactgttga aacctgatga taaagatggt atgggcaata
    22081 ctttgtatat tggcagtctt aagagtgagg tctatttctg tttgtacgaa aaagactatg
    22141 agcaatatat caagttaggg attccattag accagaccga aacgaaaaat cgttttgaaa
    22201 tccgactgaa aaatgatcga gcttatcatg caattcaaga tttgttaaaa ggtcgcagta
    22261 ttgaaagtac cacattttcc attattaacc ggtacttgcg atttgcggat aaggtggaag
    22321 gcaaaaggcg aactaactgg cccttgaatg aacaatgggg gcgcttcatt ggacggaatc
    22381 agaaggaaat tcaattaact tctgaaccga agccttatac cattgaacga acgttgaact
    22441 ggcttggacg acaagtcgcc cctacgtgga agatggccaa ggagttggat cggttgaatc
    22501 agacaacgta cattcaggat atggtaaata atactcgact atcagaccgg cacaaaaaga
    22561 ttttggagca acaaagtatg gcaattgaaa atttgattat atgaaaagag gaatcgtgat
    22621 ggaaattgtg aaagatattt tattggtgtt tggtggcagt atgcttggtg ttactgtgat
    22681 gtgcttgatg catgcaagtg cagcggcgga ccgagcaatg gaaaagaaag gaaagtgatg
    22741 aaatgaattt cggtcaaaat tt
//
LOCUS       DACGMI010000047        22633 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.048, whole genome shotgun sequence.
ACCESSION   DACGMI010000047 DACGMI010000000
VERSION     DACGMI010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.048"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            6..848
                     /locus_tag="IXT46_002039"
     CDS             6..848
                     /locus_tag="IXT46_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAQ4947942.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            845..1795
                     /locus_tag="IXT46_002040"
     CDS             845..1795
                     /locus_tag="IXT46_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAQ4947943.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            1810..2043
                     /locus_tag="IXT46_002041"
     CDS             1810..2043
                     /locus_tag="IXT46_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HAQ4947944.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            2374..2958
                     /locus_tag="IXT46_002042"
     CDS             2374..2958
                     /locus_tag="IXT46_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4947945.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            3089..3757
                     /locus_tag="IXT46_002043"
     CDS             3089..3757
                     /locus_tag="IXT46_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAQ4947946.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            3759..5183
                     /locus_tag="IXT46_002044"
     CDS             3759..5183
                     /locus_tag="IXT46_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4947947.1"
                     /translation="MKELFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSG
                     KSTLLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQNPRGQFFTTN
                     TTSELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLS
                     LNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVK
                     NRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGG
                     IKKDIKLRVEDSTLIEQIFNDITK"
     gene            5201..5770
                     /locus_tag="IXT46_002045"
     CDS             5201..5770
                     /locus_tag="IXT46_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HAQ4947948.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            5880..7634
                     /locus_tag="IXT46_002046"
     CDS             5880..7634
                     /locus_tag="IXT46_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947949.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            7588..9360
                     /locus_tag="IXT46_002047"
     CDS             7588..9360
                     /locus_tag="IXT46_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002841847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947950.1"
                     /translation="MRMQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINM
                     VPAFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLR
                     VQIADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVM
                     LLVGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEI
                     NSFNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLL
                     TGEVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSP
                     LKSFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDY
                     DEGCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAA
                     RLANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLD
                     AENEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSE
                     IYKNLIKKTKLSEKFVYEKEAQSR"
     gene            9883..10152
                     /gene="rpsN"
                     /locus_tag="IXT46_002048"
     CDS             9883..10152
                     /gene="rpsN"
                     /locus_tag="IXT46_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAQ4947951.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            10167..10346
                     /gene="rpmF"
                     /locus_tag="IXT46_002049"
     CDS             10167..10346
                     /gene="rpmF"
                     /locus_tag="IXT46_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAQ4947952.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            10378..10755
                     /locus_tag="IXT46_002050"
     CDS             10378..10755
                     /locus_tag="IXT46_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947953.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            10776..10925
                     /gene="rpmG"
                     /locus_tag="IXT46_002051"
     CDS             10776..10925
                     /gene="rpmG"
                     /locus_tag="IXT46_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003550836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAQ4947954.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            10949..11932
                     /locus_tag="IXT46_002052"
     CDS             10949..11932
                     /locus_tag="IXT46_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAQ4947955.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            11962..12084
                     /locus_tag="IXT46_002053"
     CDS             11962..12084
                     /locus_tag="IXT46_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAQ4947956.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            12102..13625
                     /locus_tag="IXT46_002054"
     CDS             12102..13625
                     /locus_tag="IXT46_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAQ4947957.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            13649..13888
                     /locus_tag="IXT46_002055"
     CDS             13649..13888
                     /locus_tag="IXT46_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947958.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(14081..14542)
                     /locus_tag="IXT46_002056"
     CDS             complement(14081..14542)
                     /locus_tag="IXT46_002056"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4947959.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(14737..14955)
                     /locus_tag="IXT46_002057"
     CDS             complement(14737..14955)
                     /locus_tag="IXT46_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4947960.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            15073..16689
                     /locus_tag="IXT46_002058"
     CDS             15073..16689
                     /locus_tag="IXT46_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAQ4947961.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(16930..18270)
                     /locus_tag="IXT46_002059"
                     /pseudo
     CDS             complement(16930..18270)
                     /locus_tag="IXT46_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(18546..18701)
                     /locus_tag="IXT46_002060"
     CDS             complement(18546..18701)
                     /locus_tag="IXT46_002060"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAQ4947962.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(18997..19329)
                     /locus_tag="IXT46_002061"
     CDS             complement(18997..19329)
                     /locus_tag="IXT46_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4947963.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(19843..20034)
                     /locus_tag="IXT46_002062"
     CDS             complement(19843..20034)
                     /locus_tag="IXT46_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4947964.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(20128..20514)
                     /locus_tag="IXT46_002063"
     CDS             complement(20128..20514)
                     /locus_tag="IXT46_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4947965.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            21208..22413
                     /locus_tag="IXT46_002064"
     CDS             21208..22413
                     /locus_tag="IXT46_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HAQ4947966.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            22430..>22633
                     /locus_tag="IXT46_002065"
     CDS             22430..>22633
                     /locus_tag="IXT46_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947967.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESIS"
BASE COUNT         7731 a         3230 c         4219 g         7453 t
ORIGIN      
        1 ataatatgct tcaaaatttt attaatggtc tgtatgactt tcacttttta cagaatgctc
       61 taattacatc tgtagttata gggattgttt ctggaacagt aggttgtttt attattttaa
      121 gaggaatgtc tcttatgggt gatgctattt ctcatgctgt tttgccagga gtagcaattt
      181 cttatatttt aggtattaat ttttttattg gtgcgattgt atttggtcta ttagcttcta
      241 tcattattac ttttataaaa agcaatagtg taataaaagg agatacagca attggtatta
      301 ctttcagttc ttttttagca ttaggagtta tccttatagg agttgcaaat agctcaacgg
      361 atttatttca tatcttattt ggaaatattt tagctgtaca agatattgat aagtggatta
      421 caattggcgt ttctgtttta gtgttggtta cagttgttct attttttaaa gaattattaa
      481 tcacttcttt tgatccatta atggcaaaag caatggggat gaatgtcagt ttttatcatt
      541 atctattaat gattctatta actttagtag cagtaacagc tatgcaaagt gtgggaacta
      601 tattaattgt tgcaatgtta attacaccag ctgctacagc atatttatat gcaaacagct
      661 taaaaactat gatatttatt tcggcgacag tcggagcgtg ctcatcattg ctaggtttgt
      721 tcattggtta tagttttaac atagcagcag gatcaagtat tgttttaaca gcggcattct
      781 tatttgtaat tagttttcta atctcaccaa aacaaaaatt tttaagaaag aaggagagaa
      841 agttatgatg agaaaatgga aagcagtact gggaagtctg gggattttga ttgctctttt
      901 tatattcggg gcatgttcaa caaatagtaa agacaaagat acagtggctt cgaacgaaaa
      961 attaaaggta gtagttacta attcgatttt agcagatatt actgaaaata tagcaaaaga
     1021 taaaattgat ttacacagta tcgtacctat tgggaaagat ccccacgaat atgaaccttt
     1081 gcctgaagat gttcaaaaaa cttcaaaagc agatttgatt ttttataacg gtgttaactt
     1141 ggaaactgga ggaaatgctt ggtttacaaa attagtaaaa aatgcgaaca aagaggaaaa
     1201 caaagactat tttgcagcaa gtgatggcat agatgttatt tacttagagg gtcagagtga
     1261 gaaagggaag gaagatcccc atgcttggtt aaatttagaa aacggtatta tttacgctaa
     1321 aaatattgaa aaacagttag cggaaaaaga tcctgataat aaaaaattct ataaagaaaa
     1381 tctagataag tatattgaaa aattggattc tctagacaaa gaagctaaat ctaaatttgc
     1441 ttcaattccg aatgataaaa aaatgattgt tacaagtgaa ggatgcttta aatatttctc
     1501 gaaagcgtat aatgtgcctt ctgcttacat ttgggaaatc aacactgaag aagaaggaac
     1561 accagatcaa ataaaacact tagttgaaaa attacgcaca acaaaagttc cctccttatt
     1621 cgtagaaagc agtgtggacg atagaccaat gaaaacagta tcaaaagata ccaatattcc
     1681 tatctattca acgattttta ctgattcaat tgcagaaaaa ggacaagatg gtgatagtta
     1741 ctatgcgatg atgaaatgga acctggataa aattgctgaa ggcctttcga aataatttgg
     1801 agggtaggta tggtacaaat taaaacgact actatactaa tttatttact agcaattcag
     1861 gaattatcaa aaagaaaaaa gaaattaaaa aataatgatt tagcaaaagt tctaagtgtt
     1921 agtccagcat ctgtaagtga gatgctggct aaacttagat atgaggacta tttagatata
     1981 ggatttcaat taactgataa agggaaaaaa tttattgacg attacaaaaa aggttttaag
     2041 taaaagactt tatttttagg gaggataaga aaatggctat tggagtgatt atgataggac
     2101 ttaccctaat agctggatat aattttttta aatctttctc ggattatttt agaaaaggtg
     2161 aatgatttag atgagtctat taattcttgt aggattgctt tttgtatcag ttattttgct
     2221 ctttctcatt agtttagctc taaggaatga gttcagtaat agacgttaac gattgaaact
     2281 tcaagtcctg tgtaagataa tatagttaat tcatcttatt aggaggaagt acccatagaa
     2341 accagagatt atattacaac tcaccaaaaa ttaatagaaa gtggactaag ccattttgaa
     2401 aaagaaggat ttcagcaaac taagataagg caactgtgct tgaccgcagg cgtaactacg
     2461 ggtgcttttt ataaacattt tacttctaag gaagcgttat ttgaagaaat tattcagccg
     2521 catattaatg cgcttattaa tatgtataat gaagagttta ccaaatacct cttaaactta
     2581 gaaaatatag atatagagaa aagttggaga gagaacttca atgaattaga tccatttatt
     2641 aattatattt ttgagaataa acgtatattc gatttggttt tattccaatc agctggaacc
     2701 aaatatcaag atattgttga aaaaattaca tcatttgtga caaaaaagac agtctgttgt
     2761 ctagataagt taaagactat cggaatgatc aatcaaaatt tagtctttaa tgaagaagaa
     2821 atccacttct acatttactc attctacgct acattctatg atatattgaa gcatagctat
     2881 tcaaaagaaa agactatgct attaaccaga agattgtatc aattttctgt tcctgggtgg
     2941 attgaattac tgagttaatt aaaaaaaagc ttgcattgag aattgttctc agttatgctt
     3001 tttgataaga tcgcactgtt atctgaataa cggtgcattt ttgtcagctt aagataacag
     3061 tgcgatctta ttttttggag gtgaaagagt gtcaaaaatc aatccgttaa ccttgattac
     3121 tttaaatatt ttttttccgg tcattatttt tttaggaaag ggaaatatat ttcaagtggg
     3181 gtgtttcatt attgctacag ttttagtatt gatgtttcgt aaaataaaga catgtattta
     3241 tttcatcttg atttattcag ttctgttttt agtaatgaaa attattgatg ctatcaagat
     3301 agagtttttt actatatttt ttgggacatc cttatatatt gtatttcgaa tgttgccggt
     3361 cgtaatgatc tcatggttgt tggttagtgt ctatactagc aatgaattat tatcctcttt
     3421 agaaaaaata catttaccga aaaaaataat gttaagtatt acagtagtga tcagattctt
     3481 tccgacttat cgttctgaaa taagaatgat taaagaatct ttaaaaatga gaaacattcg
     3541 cttgtctttt tttcagcctc tgcaatattt ggaatttctg ttagttcccg ttcttatacg
     3601 tgcaactatg attgctgaag aaatgaccgc taatgcaata acaaagggga tagaatctcc
     3661 tgtgaaaaga agttcttact ataaaacaaa catgagctta ttagactata tcatcctgtt
     3721 ttccgttact atttttttct taagtatttt gatttgaggt gaaagaattg tttgaattta
     3781 acaatgtttc tttttcatat aaggatgtta aggaacaagc gcttgttgac cttaattttt
     3841 caataaaaaa aggcagtctt acattgatta ctggttcttc tgggagtggg aaatccacac
     3901 tattaaagtt aatgaatgga cttattccaa gactttatga cggaaaattg gttggggaaa
     3961 ttttatttga aaataactcg ctacaatcct taacacaaga aagtatatca aaaaatattg
     4021 gctacgtaag tcaaaatcct agaggacaat tctttacaac aaatacaacg agtgagttag
     4081 tattttcgat ggaaaacttt ggatttacaa aagagcatat ggataaaaga atcaatgaat
     4141 tagctgaatt attagatctt tcaaatatat tagataaaaa cattttttcg ctatcaagtg
     4201 gtgaacggca gaaaatttct attggatgta gtttatcgct aaactctaaa ttaattatat
     4261 tggatgaacc gtcttcaaat ttggacttca aagcgactaa gaaacttgct gacttacttt
     4321 gtgatttaaa aaataaagga tttactattg ttatagctga acatcgtttt tactatttga
     4381 aagaattaat tgatcaagtt ctatttgtta aaaatagaac tgtaaaaact acaactattc
     4441 agttgttaaa aactgaaaac aataacgcat taaggaaatt tgacattttt aatagttcga
     4501 ttgaagttcc ctatatcgaa aaggtaagtg cagatgtatt aaaagttgaa gaaattactt
     4561 atgaaaatat tctaaaagac ataaattttg atgtcaaagt tggagatgtt attggtttgg
     4621 tagggaaaaa cggtgtgggg aaaacaacct tactaagaat actcatgaag attattcgcc
     4681 ctaccaaagg aaagataatc gaaaataaaa aaaatttgtc atcgccgttt ttagtaatgc
     4741 aagaaatgga ttaccaattt ttcacagaat cagtgaggag cgagttagcc ctggggaatg
     4801 aaatagttag taaagatcag caagaaaaaa ttttaaaaaa aatggaactt tataaaatga
     4861 aagatcaatt accgtttgat ttatccggtg gagaaaaaca aagattattg gtttctatag
     4921 cttcattgtc aaaaactaat ttatttctat ttgatgaacc tacaagtggg ttggattata
     4981 tcaatatgga aaggattgct gaccttatta aagacttaaa agaaaagggt gcagtagtta
     5041 tagccactca tgatccggaa tttctttata aaacatgcaa tagaattatt tatttaaaaa
     5101 atggtggaat aaaaaaagat ataaaactta gagtagaaga ttcaactttg atagaacaga
     5161 tttttaatga cataacgaaa tagaattgag gagaatatat atgaaaacaa aagattatat
     5221 ttttattggt ttagctacag ttatttccct agtaatttac tttttttcaa taatggttag
     5281 tagtattggt ggggcgtttg gtcacagcat atccccaggg atttttggat tattatctgg
     5341 aatcatattt gtttatatta gctataacta ccctagaaaa ggaattttta ctatttacac
     5401 aattgtttta ttgttatttt ttacgttaat gggcggggcg tacttacctt ggtttatcag
     5461 ttcgattagt atggcgatct tagctgatat tattctatct gtatttggat atgatcgagc
     5521 aattcctcaa gttgtgtctt gggttctaat gcaactaggc agtgctgccg gacagtggat
     5581 tcccatatgg ttctttacag atcgttttcg tcaagactgg atagatagag gacaatctgc
     5641 tgcaacaatg gatgcaatga tccactacgc ggtgggtata tggggaatta tttcagtgtt
     5701 agttgtagca agtttatcta tgattggtgt attgattgga agaaaagtct taaaaaaata
     5761 caaaaaatag aacgtagttt accttctatc tgtttgtaca tctctaattt acgctattac
     5821 ggaaagcatt aacagttgta aacgaataag agaagaaatt gaatgcgggg gaggaaaaaa
     5881 tgaaagtata caaaaaatta tttagttatg tccctaaaat gaaatactac ggatggttag
     5941 ccactttatt ttctgatttt tctgtcgtat taacagtcta tggatattac agtatttaca
     6001 aatttcttca gtctctaatt attgtaggag atgaatattt agctaagagt tatgcggttc
     6061 aaactgttgc ttggttaact ttaggagctt tattttatat tttttctggc ttattttctc
     6121 atatccttgg gtttcgctta gagactaatt tgagaaaaaa gggaattagc ggtttaacag
     6181 aagcaagttt tcgttttttt gatttaaatt cttcgggata tattcgaaag acaattgatg
     6241 acaacgcggc taaaacacat atggcaattg ctcacttgat tccagatagt gctcaagcca
     6301 tagtaacacc tgttttatca gttgccttag gctttttcat taactttaaa attggattgg
     6361 ttctaatcgc catgttagta attggtgtat tcttgttaaa gaaaatgaca gagaatacaa
     6421 attttattca aaaatatcaa gaatcgttag atgtgttaag ctctgaaacg gtagaatata
     6481 tccgcggaat tcaagttata aagatatttg gtgctaaagt aacatcattt aaagccttga
     6541 ataaagcaat taacgattat gctaagtttg catataagta ttctttgagt gggaaaacac
     6601 cttttgttct ttttcaatgg ctattttttg gcatagtttg cattttgata gttcctataa
     6661 ccttttttat aacttctctt accactccca agatcttagc tgttgacttg ttgatgttgt
     6721 tttttttaag tggaattatt tttgtttctt tcatgagaat aatgtatgta agtatgcact
     6781 tgtttgaagc aagatatgca gtcgaaacac tagactccct ttatttagaa atgaagcaag
     6841 accaactaaa atatgggaac gagacacaga ttaaaaattg tgacattgca tttgaaaatg
     6901 tcagcttttc atacaaagaa gagtgtgttt tagaaaattt caacttagtt ttagaacaaa
     6961 aaagaattta tgcattagta ggaaaatcag gaagcggaaa gagtacgata gctaaactaa
     7021 tttcaggttt ctacaatgtg gataagggac agattaaaat tggtggtaag cctttaaatc
     7081 actattcaaa agacacaatt attaacacaa ttgcttttgt ctttcaagat acgaaactat
     7141 tcaatcagag tatttacgat aacgtttcta tagcaaatcc tcaagcgcca gcaagtaaag
     7201 tatttgacgc gctaagatta gccggttgcg aatcgatttt agaaaaattt cccgaaagag
     7261 agcatacctt aattggtagt aaaggagttt atctgtcagg aggagaaaaa caacgtatag
     7321 ctattgccag agcaatttta aaagatgcaa agattgttat tatggatgaa gccagtgcat
     7381 ctattgatcc agataatgag tatgaactac aaaaggcttt tcaatatttg atgaaagaaa
     7441 aaacagttat tatgatagct catcgattat ccagcattaa atctgtagat gaaattcttg
     7501 tcttgtcaga aggaaaaata gtagaacgtg gaaatcataa tgaattaatg gctaaacatc
     7561 gagtgtataa acaattggtc actaattatg agaatgcaaa tgattggagg cttgacaatg
     7621 aaaaattttt ataaaaaaaa atttgcttta actgatcagg gcgcagaagc tttaactaaa
     7681 gcttctattt ctagtttttt tgtatactgc attaatatgg taccagcatt cattataatg
     7741 atgctgatag acgaattagt tttagaaaat gcaaagcccc gttggcttta ttttgcagta
     7801 tcgtttgtta ctttgctttt catgtattgg ttgttagata gggagtatga aaacttatat
     7861 aatagtactt ataaagaaag tgcgcattta agagtgcaaa ttgcagacga tttgtcaaat
     7921 ttaccattat cctatttttc aaaacataat ttatcagatt tatctcaaac tatcatgtct
     7981 gacgttgaag gtattgagca tgcgatgagt catgcaatac ctaaagccgg cggtatggct
     8041 ctgtttttcc cttttatttc agtgatgctt ttggttggta atgtcaaaat gggattagct
     8101 gttattttgc caacgttatt tagttttgtc ttaatcttgt tatcaaagaa atcccaaacg
     8161 aaagccaata ctaaatatta cgatactttg agagaaaact cggaagaatt tcaagaaact
     8221 attgaattgc agcaagagat taatagcttt aatctatcta aaaaagttca agacagactt
     8281 ttcaaaaaaa tggaagagag tgaaaggatt catttaaagg tagaattaag tactttttca
     8341 gtcatggcct tatcctctat tttctcatat gttagtttag cagtagtcat tctagtaggt
     8401 gttcacttac tgttaacggg tgaagtgact atactctacg tcgttggtta cttactagcc
     8461 gcaataaaaa taaaggattc cttcgattct atgaaagaag cagtgcttga aatattttat
     8521 ttagctccta aaatacagcg aattagagct atgaaggaaa ccagtatcca agagggatca
     8581 gatagtcctc tgaaatcttt tgacattgag ttgcgagatg tctctttctc atatgataac
     8641 aataccccaa ttttagatca tatctctttt acggctaaac aaggagaagt gactgcgtta
     8701 gtaggtgcta gtggttccgg gaaaactagt atcttgaaat tagtgtctag actgtatgat
     8761 tatgatgaag gctgtatttt aattgatggg tatgatatta aacgtgtatc tccagcttct
     8821 ttgtttagca aaatcgctat tgtttttcaa gaggtaactt tgtttaatac aagtattttg
     8881 gaaaatatac gtattggaaa tagtcaagcg tcagatgagg aagtgaaaaa agcagctcgt
     8941 ttagctaact gcgaagactt tattgaaaaa ctacctgacg gttatcatac attggtcgga
     9001 gaaaacggaa gttcactttc tggaggagag cgacaacgcc tatccatagc acgggctttt
     9061 ttgaaaaatg cgccaatttt aattttagat gaaattactg ccagtttaga tgcggaaaat
     9121 gaaaaacgta ttcaggaaag tttaaatcgt ttaatacaag ataagacagt actaattata
     9181 tcgcatcgct tgaagtctat tgaaaaggta aataaaattg tagtgatgga tcaaggaaaa
     9241 ctagttgatc aaggtactca taatgagttg tatcgaaggt cagaaatata caaaaatctc
     9301 ataaagaaaa ctaaactatc tgagaaattc gtctatgaaa aagaagctca atcacgatga
     9361 tgaaataggc tttaaattaa cctacaattt ttgggatata gttataattc tttttcaaaa
     9421 agaataattt tattaaacag catctaattt tgaatacacg aaagaatcag tatgattgaa
     9481 ttagttcact taatgtctat tcttataata taaggaataa tcaaagtttt aaaaaattgg
     9541 cgataaacca gttaaacata aaagattgaa taaaaagtta tagtttcttt catattgccg
     9601 ttttaagtag aggaaaagct acttaaaacg gtatttgtgt ttgattggac taataaaagt
     9661 gaattcttat ttttcagagc ctaaactgca tattctttta aatgatttga ttatctctat
     9721 gtaccgataa attcgttttc aaatagttat ctattcatat gagttttatt tcatgttatt
     9781 tattgttgac aagagcaact cttgttggta aagtatcagt gtcaaaacgt aacgattacg
     9841 atttgaggtg tctaaatcaa aataaaagga gtataaaggt atatggcaaa aaagtcgaaa
     9901 attgctaaag caaagaaaca aatggcgatg attgaaaagt atgcagataa acgtcaggaa
     9961 ttaaaagccg caggagatcg caccgctctc gctaaattgc caagagattc aaatccgaat
    10021 cgtctgaggc ttcgtgatca gacggatggt cgtccaagag ggtatatgcg aaagttcggt
    10081 atgtcccgta ttaagtttag agaacttgcc catcaagggt tgattcctgg agtaaaaaaa
    10141 gcaagttggt aaaaggagga aatatcatgg cagtaccagc aagaaaaaca tctaaggcga
    10201 agaaacggtt aagaagaact catcaaactg tagtaaaacc agaaatttca tttgacgaag
    10261 cgaatggtga ttatagacgt agccatcatg tatctttaaa agggtactat aatggaaaga
    10321 aagtaattaa aggagcttca aaatagttta atatataact tttaggaggg aatcaaaatg
    10381 gaaattattt acccaccttt agttgaagaa ggattaaagt attatcttga aacgacccag
    10441 caatcgctag ataaatgcac tttttatcgt tcgatggtag agagaggaat tattactgaa
    10501 acgggtttac cgacccaaca ggcaattgaa aatggattag tcaaagatta ctatgaggac
    10561 caaggcttat catttgatga ttttttaaga atctatccaa tttttgaaga gtatgacgag
    10621 gagttatttc aatgtatcga tggttattgg gagatacctg ttgatatgaa agaaaattta
    10681 gtttcacaat tggaatctgg cgagttaact tttgaagatg cacaacaaat tcaagcatat
    10741 cttgaagatc gataagtatt gaaggaggaa gatttatgcg tcaaaatatt attttggaat
    10801 gtgtcgaaac tggagaacgt ctgtatctca ccagcaaaaa taaacggaat aaccctgaac
    10861 ggttagaatt aaaaaagtat tcgccaaaat tgcgcagacg ggcaattttt aaagaagtga
    10921 aatagctaag tggtaaaaag gtgacaaaat gggcatacca gttacaatcg tttctgggtt
    10981 tttaggggct ggaaaaacaa cgctaatcaa tcaagccttg caagtctcac cctaccccag
    11041 ggaagaaatt attataattg aaaatgagtt tggtgaagtt gggattgatc acaaattatt
    11101 agttcatagc gaggaacggg tgttacaact aaataatgga tgtatgtgtt gcagtcttcg
    11161 cagtgattta ttagcaatat tgatttcttt actggaaaca atagaagaac atcaacaacc
    11221 aatttcacaa atcatcattg aaactacagg tatagcagat ccccaaccaa tcattcaaac
    11281 acttttaaca gcgcctcaac taagaggaag agtatatatc gatagtttat tgactgttat
    11341 tgatagtgac agttttgaac ttattgaaag agaaccacaa gcccttaagc aacttgtcat
    11401 ggcagatcgc atttttgtgt ctagaaaaca aaacttgaat ttatctgcac taaaaaaatt
    11461 acagagagaa atcaaaagta ttaacccttt atccgatatt cgaatgttca cacatagtga
    11521 aacgattcaa aaaaaggatt tttataattt gaaaaaattt aatcatccct tagtttttga
    11581 aagtgattca tcagaaaatc actataatgg caaatactat catcaacacc atcaagtaca
    11641 tgagtttaaa tcaattctct taacttcaga tcaagacata aaaaaagatt ttttactcca
    11701 atggattgac tggctgattt taaccaacca agggagcctg tatcgtttta aaggattgat
    11761 tgctttacaa gagcaggatt ttatagttgc catgcaagag gtaaacgaac aggttaattt
    11821 tcaatacacc actcgacaaa aagaccaaac cactattatt ctaatcggaa aaatgttgga
    11881 tgaagaaagg atcaaacaga gttttgataa attactggcg gaaagcaaat aatgataagt
    11941 agtgattggg ggtaatttct aatggagaaa acggatatat ctagtgcata tcgacgactt
    12001 aaaagcccga atattaaaac tagaaaaagg gcattaaaaa ttatcaaaga acataaacga
    12061 aataaaatga agaaattagc ataattaagg aaggaaaaag aatgaagaaa atcagtgtag
    12121 gacttattgg gatagcagct ctaggattat tgggagcttg ctccagcact aatgatgcaa
    12181 aagtatcgaa tgataaagat ggaaaattag aaattgtaac aacattctat ccaatgtatg
    12241 atttcaccaa aaacatcgtc ggcgatgaag cgaacgtgga tttaatggtt ccagcgggat
    12301 cagaacctca tgactatgag ccctcagcta aggatatggc aaaagctcat gatgctgatg
    12361 tttttgtata tcataacgaa aacatggaat catgggtacc aaaagctaaa gaaagttgga
    12421 agaaagctgg gcctaatgta gtagaaggaa caaaagacat gattttattg ccaggtagtg
    12481 aagaagaaga tcatgatcac ggagaagaag atcaccatca tgaactagat cctcatacgt
    12541 gggtttcacc caaaatggca attaaggaag tttcaaatat caaggatcag ttagttaaat
    12601 tgtatccgaa aaaagcaaaa gtatttgaga caaatgctga aaagtatttg actaaactga
    12661 aacggttgga tgctgactat accactagtc ttaaagaagc gaaacaaaaa agttttgtga
    12721 cgcaacacgc agcctttgga tatttagctt tggattatgg attgaaacaa gttcctattg
    12781 ctggactaag tcctgaagaa gagccatctt ctggtcgatt agctgaatta aaagagtatg
    12841 ttaaaaaaaa taagatcaat tatatttact ttgaaaagaa tgctaatgat aaaattgcaa
    12901 aaactttggc caacgaagct gggataaaat tggaagtact gaatcctctt gaaagtctta
    12961 caaaagaaca aatggataat ggtgaagatt atgtttcagt aatggaagac aatctaaaag
    13021 cgttagaaaa aacaactatg gttgctggtg aagaggtagt tccagaaaaa gaagcgaagg
    13081 atgaaaagac agttgctaat gggtacttta aagatgccga tgtgaaggat cgcgaattga
    13141 gtgattatac aggcgaatgg caatctgttt atccgttgtt aaaagatgga attttggatg
    13201 aagttttcga ttacaaagca aaaatcaata aagacatgac agctgccgag tacaaagatt
    13261 attatactac tggctataag acagatattg atactatcaa cattaaagac aacaccattg
    13321 attttgtagt caacggtgaa catcatcaat acacatacaa atatgttgga tacaaaattt
    13381 tgaattatga aaaaggaaac cgtggtgttc gttttaattt tgaaactgat gatgcaggtg
    13441 ctggtcgttt taaatatatt caatttagtg atcatggaat tgcaccaagt aaggcagagc
    13501 atttccatat tttctttggt ggagaaagtc aagaaaaact ctataatgaa ttgcataatt
    13561 ggcctacttt ctatccagct tcattgtcta aacatgaaat tgctcaagaa atgatggctc
    13621 attaaaattc aatttttgga ggaaatacat ggtaagaaaa gtattattgt ctatggattc
    13681 caagaatatt gatgcttatc ggcgttatcg atttgcaaag caaatgagat taaatgggag
    13741 tacattagct gatattgctg caactttaca tgttagtatt gacacagttc atagagtatt
    13801 aaaacgggat cctgattgtt gttttatcaa ggtcaatact ggaagaagta gacgtttagc
    13861 aaaacggcat aatagcttgg ccaattaatt gataatacca gagtagatca tttttccctt
    13921 atttggattt gatctgcttt ttattatgtc ttgaattgtc aaatcaagcg caacacttta
    13981 tcaaagaaga cttcataagg tgttctccaa tctaaacact ttctaggtct gttattcagt
    14041 ttttcaatca tctgatttat cgttgagtta tctaccgtag ctatctcttt cgattttggc
    14101 aagtattctc gaatgagtct attcgtattt taatttgttc attgttgcca agggcatgag
    14161 gatctggaaa ataaaagggc atattattca atgcttctgt aactgcgaaa tgattggaga
    14221 attcttttcc tctatctgga gtgatcgttt tgaccgcctc atttggaata ctgcttaaaa
    14281 gttcaatcat tttctcgctc acataagcgg ctttctttct ggggaccttc tttcctgcta
    14341 aaaggaagca tgattttctg tctgtcaaag tcactaaaca agtaccacca gttttgccag
    14401 ctacaatatc ggctttccaa tgaccaaaat cacttctatc atctgcggat tttggacggc
    14461 catggatcga atgagtaagg caaatctttc cacgagactc gacatgattt tttgtatgtc
    14521 ttgtttttcc tcgatggtgc aatgaacgga tcaggccttt attgccgtgt gagaggggtt
    14581 ctgtatcgaa aagatcattg caaattgcac gttagatcgt gataaaacta attgaaaagt
    14641 ccatatgttc atgcttcaaa cgattcgaga tttcctctgg cgaccactga aaatcgacaa
    14701 ataaatgacg aacaattgac caaactcacg gatcatttag aatgtgataa cgtccgcatt
    14761 tttttcttcg ataagcataa tttttttccg ctttggaagg tgaatagttt ttttcttgtt
    14821 tcttctcagt tcatgtaaaa tagtaaacgg gctatgctga atgtcgttgc caattatact
    14881 aatagaaaat ccttcttcgt gaagcagaaa gattctttct cgttcgagta tagtaagatg
    14941 acgatactgg ctcataatta ttttccttct aggagtgttc tcgacaaact tatactagtt
    15001 ggatatcgat tatgactcat ttttatgtgt tgcacttaaa gtgtaaattc aaggtataga
    15061 aagaggttcc ctatgaaaaa aatacctatt acaatcttaa ctggctatct tggttcagga
    15121 aaaacgatac ttctaaatca tattctgtac ggtgatcacg gaaaggaaat tgctgtcatt
    15181 gtaaatgaca taggggaagt aaatgttgat ggggtattag tcgacaagaa aggttttaaa
    15241 agaactggag aaaaacttgt ttcgatgccg aatggatgca tttgttgtac attacgcgaa
    15301 gatttgattg ttgaactaga tcaattagtg caattttctg acttgaatca aattgttatt
    15361 gaagcttcag gaatcagcaa accaattcca attattcaag caattatatt agctaaaaac
    15421 cctttagaca ttgatttgac ccaacgatta gagattggtg ccattattat agtagtggat
    15481 gtaaaacgtt tttgggataa tttcgaaacg ggtgaaaaga ttcaggaaag aaaagctgaa
    15541 ggtaatgtag ttgaagaaga acaggatatt cgtggcttgt taattgatca attcgagtgt
    15601 tgtaacatat tacttttaaa taatagtgac ttagtgtcaa ccaagacgat ttacaaaatt
    15661 aacggtctaa ttgctaagtt acagtccaat gccaaaataa ttaggacaat taaaggtgaa
    15721 gtagacttat cgaaaattct aaatacaaat ctttttaata tagatgagac ttcctattca
    15781 gtgggctggt tcaaagagtt agagcttggc tatcaaaatc atattcctga aacagaagaa
    15841 tatggtatct caagttttat ctatcgaaat cggttactcc ttgacgcaca aaaatttgcc
    15901 catcttacgg ataaaaattt tcctggcaat attacaagag caaaagggtt tctttggttt
    15961 gcccaacata gtgatttttc gacgatcttt gaaacatcgg gtagctataa aagtattgaa
    16021 tcattaaatt attgggtagc tagtttacct aaaattgagt gtcaaatgat tatacaaaaa
    16081 aatcccgaat tgaaggaagc ctggcatccg ttgtttggtg aacgcattaa taaactagtt
    16141 tttattggta tgaagatgga tcaacaatgt attaaggaac aacttgaggg ttgtttaact
    16201 gattctctta atgcagataa tttccgaaaa atttcaccat ttccatggaa aaagtctaat
    16261 atgtttagcc agatatcgtt aatgaaattt ttaagaaaag ctggtgtcaa gataggcgat
    16321 gtcataatta ttggcatttt gattattacc tcttttattc ccttatttgt attctctata
    16381 gaaaaggaga atgaaacaac tgaagatgct atcaaatatg ccatcgttcg aattgatggc
    16441 aaggaaatgg atcgcttcga tttggataag atcaatcata aactcgtgaa ttatcatcct
    16501 gcgaagggac aatataatat tgttgagatt aaagatggaa gaattcgagt taaagaagat
    16561 aatagtcctg atcaaatcgc ggttagaact ggatggatct caaaacccgg tcaaacgagt
    16621 atttgtttac cccataagtt agttattagt attgagaaaa aagaaagcac agattactac
    16681 atttactaat ctggaaatag atgaggaggt ttttaataag aaaaagatat tattattaat
    16741 aatagcaggg gctttattaa gtgtgttaag cgcttgtgga caagaaaaag aagcggtgac
    16801 aacaggcaca agtatcttta acgggacctg caatggttta gttaacagtc ggttagatta
    16861 cttattttgg ctcttcgtca atgagtgttg gtgaagaaat tcaatagaat aatcgagata
    16921 ctcacacggc tagacagcta tcttgtctag ccgtgttgtt gttctggctt tagtcagttg
    16981 ggtagtattc ttagttttct taaaatattt tcctcgatat aaaaagattc gttctcggta
    17041 gttttgaaag tttctatagc cataggcaat tcgttttagt actttgatat ggttattcaa
    17101 acattctata gggccgttgg aatagggaac gcgcaacgct cgtttgattt ctgtttggta
    17161 tttcttgaag gtcgtgaaca ctggttggta gtgctctggc aactccttgt agtcttcttt
    17221 taggagcgcg acgaattcag gaacatcttg tcttctgata acggaaagaa aatcctggta
    17281 gacttcgtag cctcgcttta aggaatcatc ataagataat agccgatcga ctatctctgc
    17341 ttctgtcaga tgatctcgaa atgacggacg ccagtagcga tgctgacctt tcaattccca
    17401 cgcattcttt tgaagtagtt tccagtattt ctttaagtgc ttcgaccgac gatccccttt
    17461 tttaaaggtc ttcattactt gaattcggtg gttggtaaaa gcccgaccaa tgtgttggct
    17521 aatatgaaag cgatcggcga cgattcgggc attcggaaaa cactctttca ccaatgtgcg
    17581 atagggtgta tagaaatctg aaaccactag acgcacttgt tcacggactt ttatagggta
    17641 gcgcaagaaa tagtcgcgta aaggattgag ttgccgattt tccacaatat caatcagttg
    17701 atgggtcttg ccgtccatca tgacaaagct catggctccc gagacatttt tcactgattt
    17761 gaattcatcg aaacacacca cttctggtaa cagctggctc aaagaaatgg ttttaggccg
    17821 aaggctgcga agtattcgaa tgacagtggt cggagaaatg tgcttcatac gtgcgatcaa
    17881 agacatagaa agaggttcgc ttaatagctc aagaatggct tgtttgactc tgcgagcaat
    17941 ggagcagcga cgatcactaa ctgaatcttc tgctaaaaaa gtctttccac agtgtttaca
    18001 tttgaagcgc tgtttgttaa tccgcagaat ggtcttgtag ttactgacat cattcaataa
    18061 gatggatact tttttccagc cctatttaat gatcgtttgt tcattttgat agtggcgatg
    18121 aaagcattcc tccggttgat aggtcaatgt gccatcaaaa gcaaaacatg tttcgtcatt
    18181 gatgcgctct ttgcgaaagg catcctcatg aaaggtaaga tttaggtcta gaatatctag
    18241 taactctttg gtaaactctg aataggacat cttgaaacac tactttgaat ggtttttgtc
    18301 gactttattc taaaggattt taaggtgtct gtttgcgttt attagaaaaa agaaaaagta
    18361 ttggcaacag aaggcgtcac caacactaga tattatagat cccttatttt cttcgcttca
    18421 aattgtcaag gagtcatcat aaattttgta tggattcttt tgtttgggta gtagtcttct
    18481 aaataatctt ggattaacac cttcatctct attttacttt tatatttgtt ggagtcgatt
    18541 aattctcatt tgattgatcg atgaaacgct tcaattactg cattgtcaac aggagtccca
    18601 gtttggctca ctgaatgtgt gatgtggtgg tcgttcaaca gctcttgata aataaaagac
    18661 cgatgctggc tacctctatc ggaatgaatt accgtaggca attctcctta ataaatttgt
    18721 aatggacgga cgacaatctc tttttttatg tgtgaatcta ccatatagta acgtagaata
    18781 cgagttgcta agtcaatata ggtggacaaa tagaggcgac cgtcattaca tggaatgtaa
    18841 gtaatatcca tcacccaaac agcatcaatt tggttctgtt caaattatcg attcaacatt
    18901 tttttaccat ttctttgatt gttttttctc taccatgaga agatttgcgt cgatgaaatc
    18961 ctcttgtgca taaattcatt tcacgcataa gaacagctac aacacgttta ttgatttcga
    19021 ttccttcatc gtaaagtttt tgagtgatcc ctggagatcc gtatcgatct ttgtgttcgt
    19081 agaacactcg tcttcctctt ttagtcgttt attttcctgt tcaagaatgt agaaatctgc
    19141 tttatcaggt aatctttttc cttgtccagc aaaagcattt ttcccgtatc gacgatattc
    19201 tgaaacccat cgggaaattg ttggacgaga gatattgtat tcttcagcaa ttttcttggt
    19261 agttactttt ttctcaagga tatcctgtga aatctttagt ttaaatttac gatcatatgt
    19321 ttttctcaat agagttcatt ccttccggta acgtaactga tagtcaagaa aagtgtatca
    19381 tagcccaact tagtatcagg gtttgtcaac taaactgtgg aagttgatag ataagagttt
    19441 ttaacaacca aaattctctt gactattttt gaaatcagac aaattttgat tggacacata
    19501 gttgaataaa tctaccgtcg ttacggaagg taaatcgcat gcttttcaat tctagaggag
    19561 aagtcctcgt tgaagtacca tagcccagtt ctggattcga cctcctgccc acttcatacg
    19621 taaataaagt aattttagga gtgagactgt gacaaaagtt atttttaagc taaaaacgaa
    19681 ttaaaaaacg ttgataatta aaatcattcg ttttagattc tatgaatcat tatagaacgc
    19741 tgtaaaatcg atactttata attataaaga agatagtttc aaatttattg ttcgaaattt
    19801 gaaactatct ttttacttat gtcacagact cccttagttg agttattctt taatttcgaa
    19861 tttcgagata gctagatata ttgcaagcat acattcttga taacaatctt gatcatattt
    19921 tccagttctc caggattgct tatgaatcaa agagctaaat cttttgagaa ttgcctcaac
    19981 agcttcttca tttccagcct ttgctaaaat gaaatcttct tttaaagaat tcataaatct
    20041 accttcttcc catggactta taatctattt ctttgggaag gaggagaacg agcaaagaag
    20101 catacaaaat tagttattat gcagatatta aaccagcatt ttttgaattt ttttgtaaag
    20161 tcgatgtttt aaatttgtcg caccctgtct tgtaatcccc agaacctttc caatttcttt
    20221 atcagtttta tcaaagataa atttttcgat aagaaaaatt tgttcaggtt ctttcaacaa
    20281 aggaaggatt tttgctaatt ttatatcttc aacaaggaga gtcacattta aaacattaat
    20341 cggttgttta aattttatag tatctttagt aaacaaatat ggtgggagtt gatcaagttg
    20401 ttcatgtttt tgaatttctt cttgtttttt ataataagta ttagcggtgt tcaaaatgac
    20461 cttttcaaag aatcgaatca actgggcatt tacgcgttcg tcgttatctg acatattgca
    20521 cacctcctcc attaagattt aaagggaaaa gaggcaaaaa acacgaaaag aagctaatgc
    20581 aattatgctg cgctgcgaat aacttctata agctcacatg cattgatagg actgctgatg
    20641 tttattttca aaaatgtttt tttagttgat aatggatagt tatctttata cttagaaaag
    20701 aaaattcata tatcttctta aatatcaaac atgtccttat ggctaagaaa atgtcttgag
    20761 ctttttacgt ataataaatc ttttctaaaa cctccttttg gataatattc ttattcgtgt
    20821 atagattgta ttttttattt cttccccctt cataattaac aactagaaaa gagttcgaat
    20881 agacacgtat ttgaacgaaa atttttattg gattcccaaa ttggaatatt tagaaacgaa
    20941 aaattcctat tatctgtata gtgcttagat aataacggat cataataatt attgtctttg
    21001 aactagatat atgtaaatag tattcatcat gatgaaaaat gatgagttct cggtgataaa
    21061 atgtactttt tacggtggaa tatacatgaa agcgataagt ggatatttta taatgaagta
    21121 agttagctta ttttgacaga ggaatagtat tttagataac gtataaaata ctatttaatg
    21181 atgtagaaag gaaagagaga aacaaaagtg ttttcagata aagaagtctt attaaagtct
    21241 cttcatgttt gtttaaagtt acctatcgtg gtttttaatt ccgaattcag tattataaaa
    21301 gagtatcgct cagatagaac tacttatttt ttttatgatt ataaaaagtt actaactgat
    21361 aatattaaaa aaactaaaga tttccatttc tttactggtg attttaatga gatgtttctt
    21421 ctatacatgt ttaaaaccag atattactta tttggtccat ttagagcaaa taatattgat
    21481 aaagtttttt ttaaactaaa aatgaacaat ttgaatgttg caatggctga tagagaacga
    21541 ctctataatt cattgcaaaa tttgactttg tattctttag gagacattcg agatattctg
    21601 attttagttc attatttttt tactggaaaa atagaagatc tattccatga accgttaatt
    21661 gaatatacag aaaatctaag taaaactatc gagcaaatca aaatagataa tctgttatca
    21721 caaaattacg atccagaaat atatctgttt ctttatgaaa ataaaatact ggaatatgtt
    21781 aaaaatggag atattcgaaa tttagaaaac atggttttta atctgagtaa tggaataatt
    21841 ccaagtgtta gtggagatac gattcggtct gaaaaaaatt attctatcat tgtttttgaa
    21901 aagttagcac aaacgtctat aacattagga atggatataa tagaagcgta tcaaagtaga
    21961 gatgctttga tacaagaaaa cgaattagct gtatcgttac ctgaggtctt aaaagtgagg
    22021 gattctggga ttgtttatta tactaaggaa atcggaaaaa ctaagataga gcatctttct
    22081 cccttaattt cttctgtcgt tcaattcatc ggcttaaata tctataaaag aattactgta
    22141 aaggaaatag ctaattattt ttctgtaagt gaaactaaat taagagaaag ctttaagaat
    22201 gaaatgcata ttacgattta taattatatc tctaagcgaa aaatttctac ggctaaaata
    22261 atgttgaaat caaaccatac tatcagtgaa gtttctttag gtttaggatt ttcagattct
    22321 tcacactttt cgagagtatt caaaaagtac gcaggtgtat ctcctaagca atatcaatta
    22381 ggtttagtgg acaatttcaa caacattagc tgagaggttt tattttatta tgagactata
    22441 tcatttacgt agtttggagg agttgaggaa attggatttt aacaaaaaat ttttttggga
    22501 aatttctgat ttgagttgtt tcgtagaatc tgagcgtcta agtaatggta ataatagtgt
    22561 gttaaatgaa tatgacaaag tagtaattaa taaagtaaaa agtttatgtg aagaagctag
    22621 agaatctatc agt
//
LOCUS       DACGMI010000048        22306 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.049, whole genome shotgun sequence.
ACCESSION   DACGMI010000048 DACGMI010000000
VERSION     DACGMI010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22306
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.049"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(224..454)
                     /locus_tag="IXT46_002066"
     CDS             complement(224..454)
                     /locus_tag="IXT46_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947968.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(703..903)
                     /locus_tag="IXT46_002067"
     CDS             complement(703..903)
                     /locus_tag="IXT46_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4947969.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(1208..2440)
                     /locus_tag="IXT46_002068"
     CDS             complement(1208..2440)
                     /locus_tag="IXT46_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAQ4947970.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            2694..3263
                     /locus_tag="IXT46_002069"
     CDS             2694..3263
                     /locus_tag="IXT46_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4947971.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(3441..3881)
                     /locus_tag="IXT46_002070"
     CDS             complement(3441..3881)
                     /locus_tag="IXT46_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAQ4947972.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            4039..4803
                     /gene="map"
                     /locus_tag="IXT46_002071"
     CDS             4039..4803
                     /gene="map"
                     /locus_tag="IXT46_002071"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAQ4947973.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            4835..5758
                     /locus_tag="IXT46_002072"
     CDS             4835..5758
                     /locus_tag="IXT46_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAQ4947974.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            5834..6973
                     /locus_tag="IXT46_002073"
     CDS             5834..6973
                     /locus_tag="IXT46_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAQ4947975.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            6966..7766
                     /locus_tag="IXT46_002074"
     CDS             6966..7766
                     /locus_tag="IXT46_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4947976.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            7766..8593
                     /locus_tag="IXT46_002075"
     CDS             7766..8593
                     /locus_tag="IXT46_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4947977.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            8571..9305
                     /locus_tag="IXT46_002076"
     CDS             8571..9305
                     /locus_tag="IXT46_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4947978.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            9405..10271
                     /gene="rfbA"
                     /locus_tag="IXT46_002077"
     CDS             9405..10271
                     /gene="rfbA"
                     /locus_tag="IXT46_002077"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAQ4947979.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            10285..10857
                     /gene="rfbC"
                     /locus_tag="IXT46_002078"
     CDS             10285..10857
                     /gene="rfbC"
                     /locus_tag="IXT46_002078"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAQ4947980.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            10879..11907
                     /gene="rfbB"
                     /locus_tag="IXT46_002079"
     CDS             10879..11907
                     /gene="rfbB"
                     /locus_tag="IXT46_002079"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAQ4947981.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            12005..12856
                     /gene="rfbD"
                     /locus_tag="IXT46_002080"
     CDS             12005..12856
                     /gene="rfbD"
                     /locus_tag="IXT46_002080"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAQ4947982.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            12891..14924
                     /locus_tag="IXT46_002081"
     CDS             12891..14924
                     /locus_tag="IXT46_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947983.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            14968..16248
                     /locus_tag="IXT46_002082"
     CDS             14968..16248
                     /locus_tag="IXT46_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAQ4947984.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYRWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            16458..17264
                     /locus_tag="IXT46_002083"
     CDS             16458..17264
                     /locus_tag="IXT46_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4947985.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            17276..18496
                     /locus_tag="IXT46_002084"
     CDS             17276..18496
                     /locus_tag="IXT46_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4947986.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            18486..20072
                     /locus_tag="IXT46_002085"
     CDS             18486..20072
                     /locus_tag="IXT46_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4947987.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            20111..22249
                     /locus_tag="IXT46_002086"
     CDS             20111..22249
                     /locus_tag="IXT46_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4947988.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT         7047 a         3774 c         4595 g         6890 t
ORIGIN      
        1 tcagtcacga tatcaaacaa aaaatatacg tctttcttca ttctagtttt cgcagcaggg
       61 attttaaagt agttcttatt agaatagtag agattaatta ataagctatc ttcgattgct
      121 aaaaagaaaa cttctgaatc ccacacctta taaaaatctt tgacaaatct attcgaagga
      181 tcaaatttaa accataattg cgtctcatta aaaagcataa ccattactcc gatctatttt
      241 taaacttagt ctctacctct aatatatatc gagtttttat tttgccttca gagaatactg
      301 tttctttttt tgcagttaca ggttgtttat tttcggaaaa agctaatata gctaaaattg
      361 aaacatccat ctggaatttg tctttttcgt tgctttgctc ataaaaatct gcatattcat
      421 cactaatatt ttttctaata aattcttcca tcataaagat cacctcgaga agagtatacg
      481 aactaatgtt ctttttgtaa aggtggaatt tattatacaa acaaatagat gaaaaagtac
      541 ttgtgccaaa ttatgtgcca aaaaaaatcg aatttaataa aacacaaaca aaaaggaatc
      601 ctattatgat aacatttctt ataataacaa acacaataga agacatgtaa tagttagtca
      661 ggaacgtaca aataacccct gtatcctttg cggtacaggg ggttattttg tataagtaga
      721 cattgtagtt tctaaactgc tatgtcctaa acgtttcgat acgctaagta tatttactcc
      781 ttgataaagt aaaatagatg catgcgtatg tcttagtcca tcaataaaca gtcgaagaga
      841 aaatagggaa aaattgatta ctaaagaaaa acttactagg tcgacggtgt agttgatttt
      901 catacttcaa tagattcgaa ttaaacgatt tcgattggct tataccagtc ctatccaacg
      961 aaagatatat cgttcttaac tctagcggta taacttgaag ctttacgtaa agccaatggg
     1021 aatgaactgg agatgacttt ttattatttt tagtaatagc tgatgggtta atacttacaa
     1081 ctttcctttt caaagtacca tataaaaaaa cggtggggtt gtttagcgaa ataaaggatc
     1141 taagccaata gcttagatcc tttattctat gctttatatt attttttgca tgtgtgcgaa
     1201 agtatactca agcccaatcg ccatttcgga aaatcggtac tgtagagcca tcttcacgga
     1261 ttccgtcgat atccatcttg tcagatccta ccatgaaatc tacgtgggtt tgacttctat
     1321 tcaatccagc ttctgctaat tcttcatcgg acatttctgt accgcctttc acactgaagg
     1381 cataagcaga acctagtgct aagtgattcg atgcgttttc atcaaataat gtattgaaaa
     1441 agatgatgcc agattgagaa ataggtgaag ggtcaggtac aagtgcgact tctcctaaac
     1501 gacgcgcacc ttcatctgta tcaagcagtt ttgctaagac atcttctcct tgttcggcag
     1561 aaaaatcaac aacttttcca tctttaaaag taaatttcat acccgagatg atggtgccag
     1621 cataactcag tggctttgta cttgaaatgt aaccatctac tcgatgactg tcaggtgctg
     1681 tgaacacttc ttccgtcggc atatttgcca tgaatttttc tccacgagca ttatagcttc
     1741 cagcgccttc ccaaagatgg tttttaggca atccgataat gatatctgta ccgggagcag
     1801 tatagtgaag ggcagaaaat tgttctcgat tcaattcttc tgcttttttt gctaattttt
     1861 catcatgctt cttccatgct aagacagggt cttcttcata gacacgagtc gttttgaaaa
     1921 tctgatccca taatgcctca acttgttttt cttctggcag ttctgggaag acttttgctg
     1981 cccattgttt accagccgca gccacgacag tccaactgac tttatttgct tgagttgcct
     2041 tgcgtaaatt cattagtgct ttgccattcg ctgattgata agacgctact cgatggctat
     2101 ctacaccagc aaatgcatcg ggatcggcag aaacaacgct gatcctgctt gctccttttt
     2161 caagccattc atccgcttga tcgattttag attgtggtac attctcaata cgatccgttg
     2221 cagcatgtaa aagaaattct ctttggatct ggtcgtcagt ccattgaacg ataacctcag
     2281 cggctcctag tttataagct tcttgtgtga tcaatcgagc aaggggtgcc tgttccacgc
     2341 tgatctgtaa aacaactgtg tgtccttttt ctgtggctac gccagtttct gcaattaagc
     2401 gtgcatattt ttttagaagt tcattaaaat cagataacat aataaaaatt cctcctcacc
     2461 attttttctg gtaactatta gcatgatacc atttaattat gattcaaaca atgaggcttt
     2521 aaataaaaaa aggaggttat ttttttaagg ttaagtttca tgatatatgt tactacttgc
     2581 tatttcagct tgtgaagaaa atcaaaaact aattttgcat atcaaaaaaa catgttacaa
     2641 tgaaattaat caatggtgga agcgttataa aaaaattaag gagattaaaa aatatggcaa
     2701 gaaaaaagac gattactaga gaacagattt tggcagctgc ttatgaagta gctgccaccg
     2761 atggatttac acgatttact gcgagaaaca tcgcgaacaa aatgaattgt tccacgcaac
     2821 cgatttatct tgagtttaaa aatatggatg acttgagaca agctcttttt gagcagatct
     2881 atgatcattt acaatatgaa gtgttcactg ttgagcatac agggaatacg attatcgatc
     2941 ttgcttttaa ttatatccat tttgcaagaa gagagaagaa gttgtatcgt tcactgtact
     3001 tagaagaata tggtggagga aaagagatgc agaatttctc ttatacttac tttgtgaata
     3061 cagtgaaacg cgatccagct tatgtgaatc tttcagaaga gcagatcgaa tctttgtata
     3121 atgggacatg gatcatagct actgggatcg cagctttgat gtcttcaagc atcatccatc
     3181 caactgatga acagattgaa aagatgatcc aagacagtat agatgctatc ttgaaattca
     3241 aagaaccaat cgaaatcgat tgaatatact caaaagttcc acaaatcagt aggtaacaag
     3301 agatgtgtca aaataaggaa aagttcgttt ttcttacagc gtatgcattt ttaactcccg
     3361 aagaactctt ccatgaatgc aatgaataaa agagccatac agattgaata aatctggatg
     3421 gctcttttat tgcaagtata ttaaattttt gcgactagtt ctttagcgaa agcttctaaa
     3481 ttttcgatat cttcttcttc agcattcaga tccactttaa cattttcggc tccttttgat
     3541 gcgcctgttt ttgcaaaagc agcatcgaaa tcatccaccg atttgcagaa ttcatcgtaa
     3601 aaagtatcac cagatccgca gacaccgtaa atttttccca atagatccaa ttcttgcaag
     3661 tcttcataaa agtctacgat ctcatcaggc agatcgccat catcgtatgt ataagtagct
     3721 actacgcaaa tatctgcctc ctcgaattca tctgcatcta cttgggtaca ttcgttgatt
     3781 tcgacttcga tatccagatt ttcaaatgct tctgcaacaa tatcggcgat ttcttcagtg
     3841 tttcctgtca tgctagcata tacgattttt gctaaagcca tgatgtgcct cctcgtttat
     3901 aattatttaa caattatgaa ttataccaaa acatcattga aaagaaaata aaacctaaag
     3961 acacctgggg aatgtcattt ggctaaatgt atgccgctat gttaaaatga gagggatttg
     4021 taaaaaggag acgaaaatat gattacttta aaatcagcac gtgaaattga aatgatggca
     4081 gaatctggag ctttattagc agatgtacat aaaaatctgc gtgattttat aaaaccagga
     4141 atcacaagtt gggatattga ggtatttgtc agaaactata tcgagagtca tggcggaatt
     4201 gctgcgcaaa ttggctttga agggtatgaa tatgcgactt gtatcagtat aaatgatgaa
     4261 atttgtcatg gattccctcg taaaaagcct ttgaaaaacg gtgatttggt aaaagtcgat
     4321 atgtgtatcg atttgaaagg cggcatttct gattcttgtt gggcctatgt agttggagaa
     4381 tctacacctg agatcgaccg attgatggaa gtaacgaaga aagctttgta catcggtatt
     4441 gagcaagcac aagtagggaa tcggattggt gacatcggtc atgctatcca aacttatgta
     4501 gaaggcgaaa atctagcgat cgttcgtgat tttattggtc atggcgttgg tcctacgatt
     4561 catgaagaac cagcagttcc tcattacgga gaagctggaa aagggttgcg gttgaaagaa
     4621 ggcatggtta tcacgatcga acctatggtt aataccggaa cttggaaaat gaaaatggat
     4681 cctaacggct ggactgcgta tacaagagac ggcggacttt cttgccaata tgaacataca
     4741 ttggctatta ctaaagatgg tccaagaatt ttgacatcac aaggagaaga aggcacttat
     4801 tgatctatcc agtcaatagg tacgggagag gtacatgaaa gtttggaaca aaataaaaca
     4861 aaatgaaaat ctgatgcgct ttattgagac gactcaaaag cgcatcactg attcagaaat
     4921 gagtacgacc tctgtcgtcg ttgcttatta tttactcttg tctttatttc cattgattat
     4981 tgcttttggt aatattttac cgtttctcca catcgatcaa gagactgtac tgacctattt
     5041 acgagaagtg attcctgaga ccgtttacca gtttatcggt cctgcaatca aagacctttt
     5101 gacacaaagt tcaggaggct tgttatccgt ttctgcatta gcggctttat ggtctgcaag
     5161 tcaaagtatc aatgctttgc aaattgcgat gaataaagcg tatggcgtag aaaatagaaa
     5221 aaattttttg atcgtccgtt tcttctcact aattgtcatt gtcttgttca tgattgctat
     5281 tagtggggta actatcgttc ttgggttggg acagctgatt ttggatgcta ttcagccaat
     5341 cgtacaaata cccgtgaact ttatcgatca gttccaaact ttgaagtggc caatcacatt
     5401 ggtagcttta tttgtcatca tgttcttgat ttatttaatt gtccctaatg ctcagttgaa
     5461 gttgaagacg atcattccgg gcacgatctt cgctactgtc ggctggatgc tgttatcaca
     5521 agtgtttagt atctatgcta ggtattttgc aacgaggatc agcggttatc agatcatagg
     5581 aagttttatt gtactcatgc tttggcttaa ttttgctgct acgatcatca ttttgggcgg
     5641 aatcatcaat gcagttgttc aagaatacgt gacgggtcat caaatcaaaa aacgtcgaga
     5701 tccaagccga aaatggttca ataaattgaa aactaaattt tctcataaaa aaaagtagaa
     5761 acaagagttc ttattgtaaa tttatatcag taatttataa taattatgac tcttaattaa
     5821 agtaggtgcc catatgcttg tttcttttag tatggttata agattttttc tgacaatttt
     5881 attatcactg atattaacac ctgtattcaa aatcatttca gtacaaacag gtatggtcga
     5941 caaaccaaat gaaagaagaa taaataaagt tccaatgcct tcagcgggcg gactgcctat
     6001 ctttatttca tttgttatat cgactttatt cttattccgt aaaattatcc ctcaatcgta
     6061 tattgtaccg atcttgattg cttctttagt aatcatagtc acaggagtgc tcgatgataa
     6121 atatgagctg acacctaaac aaaaaagtat agggatcttg attgcttctc ttattattta
     6181 ttttgtagca gatatacgta ttgattcctt cacgcttcct tttattggat atatccaact
     6241 aggctggctt agttttcccg taacgatttt ttggatcttc ggtatcacga atgcggtcaa
     6301 tctgattgac ggtttggatg ggctggcggc agggatttca ttgatcggtt taattacgat
     6361 aggaatcatt ggatattttt tcctccatgc ttctacagtg tatattccag ttgttatttt
     6421 ctgtcttgta gcaagtatta tcggtttttt tccttacaat ttttatccgg caaagattta
     6481 tttaggcgat acaggagctc tattcctagg gtttatgatg gccgtccttt cactacaagg
     6541 gctgaagaac gtgacttttg tttcatcgat ttctttgctg atcgtcatgg gagtgccggt
     6601 aacagacacg ttttttgcta tcattaggag aaaagcaaac cgtgtttctt tttctacagc
     6661 agataaaaaa catcttcatc accgactaat cagtttaggc tttactcata aaggtgctgt
     6721 cctgacgatt tatgcgatgg ctttgatgtt ttctttcaca gctatggtca tgaattatac
     6781 tggaagaatc ggaacgatca tattgattat tgccatgttg tttgctgcaa ttttattatt
     6841 tgaattgatt ggtctgatca atgagaaaca tcagtttatt ttaaaaacat tgcgattttt
     6901 agggaataaa gagtaccgta cgcaagtaaa acagaaatat ttgaagaaat ggaaccgtca
     6961 tatagatgaa taacaaatta aaccagccga tccttattag tattgtgacg gcaaacagtg
     7021 ataaaatttt tcggacacta gataatttta tttcaactgt aaaagatgaa acagcagtaa
     7081 aaatccgaat ttttgacaac aattcacttc ccgagtacaa aaaaagacta acagagtata
     7141 ggaaatatcc ctacatcgat atctattttc atgatgaaaa ttccggattt ggttatggac
     7201 ataatcacaa tctgatagct agcgattctc gctatggcat tatttgtaac ccagatattt
     7261 tagtggatga agagacagtt acagcattgg tcttgttatt gaaagaacat ccggaatgtg
     7321 cgatgttagc acctaagatt cttaatgaag atggaacaac tcagcacctc atccgtgagc
     7381 agctggctgt ttttgattac gttttgcgct ttgtgccttt caaatgggtc aaaaaaaagt
     7441 ttgacaaacg actggctgtg tttgaatgcc gaggattgcc tactgatgct aatagttatg
     7501 tacggatgat ctcaggtagt tttatggtag ctgatattga taaatttaaa gagataaagg
     7561 ggtttgatga gcgtttcttc atgtactttg aagacaacga cttgtgtttg agttttgaaa
     7621 aagcaggtta caagttattg tacacaccct tttatgcagt tatccatttt tacgggaagg
     7681 gtgcgcatcg aaatgcaaaa ctgtttcgcg tgtttttgac ttctatgatg aaatttttca
     7741 ataagtgggg gtggcgtttt ttctgatgaa accagaaata ttagtagtcg ttgtgcttta
     7801 tcagcaacta ttcagtcaat ctccagctta tggaccatta agcaaagcac ttagcgaaaa
     7861 gcaaattcag cttattattt acgataatag tcctcaaagg cagcaaaatg agctgtttga
     7921 aaaagaaaat atcgtttatc atcatgatcc gcaaaatcct ggtttagcgg tggcttataa
     7981 ttttgcgttg tctcaagcag atgaaggaac acgttgtctc gtcactctgg atcaggatac
     8041 gaggctagtc gacgattatt ttgaactatt gcgtaaagta acctttacag atgaatgtgt
     8101 tgctgcagtt ccgatgattt tttctgggag ccgacaagtt tctcccctat attcagatcg
     8161 ttatatcaat cgtacagctc aagcagtaga agttgaaggc ccaacagctg aacgaatcat
     8221 ggcaatcaat tcaggtgttg cctggtctgt caaatttcta aaaaagattg gcgggtttaa
     8281 tcctgctttt tctttagatt ttttggatca ttggctgttt tggaaagtgg atcagttgga
     8341 aaaaactgtg gagatccttc ctgtacgaat ggaacatgat ctttcggttt tagactatga
     8401 aaaagtttca agtaatcgat accgttctat tttacaagca gaaaatcgat tttatcatga
     8461 atatgatcaa aggcatttat ccagtcaccg acgacaatta ttgttaagaa cagctaaaca
     8521 gttcttgacc gtcaaaaacc ggcatatctg gcggatgact ttgcgctcat atgttaagaa
     8581 ttggaaggtg tgaattcgtg cgttcggttt gtatagctac ctttaatgga ggcagatatt
     8641 taagagagca gttagatagt attttatctc agctttcagc agaagatgaa gtagtcattt
     8701 ctgatgatgg gtcagtagat gatacatggg atatattaac tgaatacgca gaaaaagata
     8761 agcgaatcca gcttttttcg gggcctcgtc aaggattgat cgctaatttt ggttatgcga
     8821 tccagcagac gaaaggagat ctaatctttt tggcagacca agatgatgtt tggttggaga
     8881 caaaagtgaa aaagatcact gactattttg agcagaatcc ggatcagcta gtagtagttt
     8941 ctgatttaat cattgtggac agcgagctgc aagagatcca tgattcgtat ttttcgtttc
     9001 gaaattccaa agaaggatgg cttaataatg tgataagaag tcactatatt ggtgctggta
     9061 tggctttccg gtcttcttta aaacccgata ttttgccgat cccgtcagaa gtgccgatgc
     9121 atgatatgtg gattggtttg ctgggaggaa agaagactgg gttcctaaga gaaccgttaa
     9181 ctctgtaccg aagacatgat ttaaacgcga gtgagattga aacacattct aaattacggc
     9241 aaaaaatttc ttggcgtgtt catctgatta cggcgttgat caaacgaaaa tggtttaaac
     9301 gttgataaaa gatgtttaaa tccttaatat ttccatgaca aatataacaa ttgatgagat
     9361 aataacaaag tgaaatttga aatcaaaaag gagagcagat atccatgaag ggaatcattc
     9421 ttgctggggg cagcggaaca cgtctgtacc ctttaacaaa ggcaacatcg aaacaattga
     9481 tgccgattta tgacaaacca atgatttatt atccaatgtc tactctgatg ttggcgggaa
     9541 tcaaagaaat tctgattatt tcaacgccac aagatacacc acgtttcaag gaattatttg
     9601 gaaacggaaa tgatttagga ctgcagatcg aatatgcagt acaagaaagt ccagatggat
     9661 tggcacaagc gtttatcatt ggagaagaat ttattggaga tgatagtgtc tgcttggtat
     9721 taggggacaa tatttactat ggtggcggtc tgtctaaaat gttgcaacga gcagcttcaa
     9781 aagatacagg cgcgacagta tttggctatc atgtcaatga tccagaacgc tttggtgtag
     9841 tagaatttga tgagaatatg caagctttgt cgattgaaga aaagcctgct cagccaaaat
     9901 caaattacgc tgtaactggc ctttattttt atgacaatga ggtaatttct atcgctaaag
     9961 gtatcaaacc ttcagaacgt ggagaactag agattacgga tgtcaataaa gcatatttgg
    10021 ataaaggaaa actatccgta gaacttatgg gacgcggatt tgcttggctt gatacaggaa
    10081 cacatgaatc attgcttgaa gcatctacct ttatcgaaac aattgaaaaa cgtcagaact
    10141 taaaagtggc ttgtttggaa gaaattgctt accgtatggg ctacatcgat aaggaacaat
    10201 tgctggccct tgcacagcca ttgaaaaaaa atcaatacgg tcaatattta ttgaatttgg
    10261 ccgctgaata aggagtcctt acagatgaaa gtaacagata caaaattaac agatgtcaaa
    10321 atcgtagaaa tggacgtctt tggcgatcat cgcggtttct tcacagaaag ttattcaaaa
    10381 gcaaaatttg cagaacatgg attgaaatat gactttgttc aagacaacca ttcactatca
    10441 gctgaagctg gtgtccttcg ggggcttcat ttccaaaaag gagaagctgc acagacaaaa
    10501 ttgattcggg tagtcactgg agcagtttta gatgtagtag tggatatccg caaaggtagc
    10561 ccgacttatg gtcaatggga cggatttatc ttatctgaac ataatcatcg acagttgctt
    10621 gtacctaaag gatatgccca tggattcgtt actttgacac caaatgtgaa cttcctttat
    10681 aagtgtgata attactataa tgcagaagca gatgggggca tcgcatttga tgatccagat
    10741 ttagcgattg attggccaat tgatccatca agagcgatta tgtcggaaaa agatcaccgt
    10801 catccgacat taaaagaatt tgaagcagaa aatccatttg tttacggaga aatctaagaa
    10861 ttaaggagaa attttcttat gaaaaacatc attgttaccg gaggtgccgg attcatcggc
    10921 tctaatttcg ttcattacgt ggtaaacaat catccagaag tgcatgtcac tgttttggat
    10981 aaactgactt atgcaggaaa caaagagaac ttggccggac ttcctagcga tcgcgtagaa
    11041 ttggtcgtag gagatgttgc agatgcagaa ttagtggacc gtctagtaaa agaagcggac
    11101 gcagttgttc attacgcggc agaatcccat aacgataatt cattaaaaga tcctttccca
    11161 tttgtacaaa cgaatatcat tggtacgtat acacttttag aagcttgccg caagtatgat
    11221 gtacgctatc atcacgtatc tactgacgag gtttacggcg atcttccatt acgtgaagac
    11281 ctgccaggac atggggaagg cgaaggagaa aaattcactg cggaaacacc atataatcct
    11341 tcaagtccat attcttctac aaaagctggt tcagatctgt tagtaaaagc atgggtgcgt
    11401 tcttttggct tacgtgcaac catttcaaac tgttcaaaca actatggtcc ttatcagcat
    11461 attgaaaaat ttattcctcg ccaagtaacg agtatcttaa gcggtattcg tccaaaatta
    11521 tatggcgaag gaaagaatgt tcgtgactgg atccatacga atgatcattc ttcagcagtg
    11581 tggctgattt tgacgaaagg cagaattggc gaaacctatc tgatcggtgc agacggtgaa
    11641 gaagataata agaccgtgat ggaattgatc ttagaaatga tgggccaacc aaaagacgca
    11701 tacgaccatg taaacgaccg cgcagggcac gatttgcgtt atgcaatcga ttcgacaaaa
    11761 ttgcgagaag agctaggttg gcagcctgag tttacgaact tccgtgatgg gttggctgac
    11821 acgatcaaat ggtacgaaga acatgaagac tggtggaaaa aagaaaaaga ggccgttgaa
    11881 gcagcatatg ccaaaaatgg acaataatac agaggaaatt tcactgtatt aatggaaaaa
    11941 cacatgtgag gcaggcgctc gcctgtctct tttttaaaat aaaaatcaag gagcggataa
    12001 ccatatgttt ttattaactg gaggaaatgg acaattaggt acagaattgc gccatttatt
    12061 agatgaaaaa aatctgccat atgtttcaac agatgcaaaa gacttggata tcacagatgc
    12121 tgagaaaaca atggcttata ttacagaatt aaaacccgat gttattttcc attgcgcagc
    12181 ttacacagca gtagataaag cagaagaaga agcaaaagaa ttagatgaga aaatcaatgt
    12241 cgatggcaca agaaatgtag cacttgcagc aaaagctgtg aatgcacaat tcgtctatat
    12301 cagtacagac tatgttttcg atggaaaaaa caaaaatgta gaatacgaag tagacgacca
    12361 aacgaatcca ctaaatgaat atggtcgtac gaaattatta ggcgaaaaag cagtagaaga
    12421 gattttagaa gactattata tcatacgaac ttcttgggtt ttcgggatct atggacacaa
    12481 tttcgtcttc acgatgcaac gcctagcgga aacccgcgac aaactgactg tagtaaatga
    12541 ccagtttggg cgaccaactt ggacacgtac tttggcagaa tttatggtat atgtcatcga
    12601 agaaaaagca ccatttggta tttatcattt gtcgaacgaa aatagctgtt cttggtatga
    12661 gttcgcaaaa gaaatattga aagatacaga tgtagaagtt gcacctgtta cgtcagaaga
    12721 atttccgcaa aaagcaacac gtccgcagta ttcagtcatg agcctgaaaa agacagaagc
    12781 gttaggtttt gtcataccaa cttggcaaga agcacttgcg caaatgctgg aagctgccaa
    12841 aaaaatgaat aagtaatttc ctttttatca aatagaattt ggagcatgat atggaaaaac
    12901 aaacaagaag tgcacgacga aaagaaaagc caaaagcgaa tcaggcagat tcgaatttgg
    12961 tgcttgacct gtttctaaaa ctccgctatc ttattggcgt tttagtcatc gtggtcatcg
    13021 ttacttttaa tttaaacgga agttcacttg gtgtttggga taaatatgtg tcgcaaagag
    13081 acgatgggaa aaaaactgat gtgatttttg gacagaatcg ggaagtgcgg tcagacgaat
    13141 ggctggtgca gacacctttt tacctctcac aagctgaaga ggacttttcg ttggtgaacg
    13201 aggattattc attaaacgga caaaacatga tcattgcgta taattctcct gtaaaggata
    13261 ttacggttat cggaaaacca ttcaactggg gattcttttt cctcggaaga gatcgaggac
    13321 tttcctttta ttgggcgatg aaattagtcg tcatggtctt gcttggattc gaagtactga
    13381 tgatattaac gaagaggaaa aaagctctat cgctaatcgg tgcatttgcg ctgacatttt
    13441 ctccagcagt ccagtggtgg ttcatgcaac atgtgggcga tttgattttc tttactttgg
    13501 gactgatgat tgctttttat cattatttct acaatcatga taaaaaatgg ctacgaacgt
    13561 tgatgatgct tttggtggtt attttcggta ttgggtttat tttagtgatt tacccagccc
    13621 atcaagtgat gctggcgtac ttgctgattt tttattttgt tggcctgctt atttactata
    13681 gcaagaaagt ttcatgggat ctgttggatg tagtgttgat tggaggggca gttttattta
    13741 ttggcggagt catggttcat ttctggctaa cgtcaaaaga cgcattgtta gcttctttga
    13801 ataccttata tccaggaaaa cgggtaagta ctggaggaaa gtggacgatt ggcgaatttt
    13861 tttctttcct tacaaattgg aaaattcctt ttgaagatat caactattcg aataactctg
    13921 aagtggccct gttctatcac ttttttccaa ctgtattcct agcaagtcca tttgtgttat
    13981 ttggcaaaaa agatagcgaa caaaagttac tgggacgtat tttgatgatt ttttgtctgt
    14041 tttctatctt ttggattacc gttgggttgc caaaatggct agcagaaatc actctgctgt
    14101 cttatgttcc tccattaaga gccatcctta cttttagttt tgcggcttgt ttattatcga
    14161 tctggtttat cgcttatatt tggagagaag atgttattcc tatttggtat aaattcattt
    14221 tgttggcagt aaatgcatgg tcttatttct atgcgattac gcattcgaaa atggataatt
    14281 atttttcgga ttttgaaacc atcgcagttg ctgtgttggg aacagtgatt ttagcttttg
    14341 cattatttgg ctggagacgc ttgttttacc tcgcttttgt cgccttagtt atcgtatctg
    14401 gctttttcgt caatccagtc gtagaaggta caggagcgat ttttgaaaaa acactggcaa
    14461 aagaaatcca aaaaatcgat caacaagatc ctggtaaagt ttggttgtct gaagatgaat
    14521 tatataactt caccccaaca ttgggagtga aatccttcaa tacagtacgc ttttatccag
    14581 atatagctgc atggaagaaa atcgatccga aagaagaata cgagaagtat tataatcggt
    14641 atgctcatac aagagctttt atcgctaagg aagatacaaa gttcatttta gatcgtccag
    14701 atatgttttc ggtcacgttg aattttgaag acgcagaaaa attagggatc gactatgtga
    14761 tcagtaaacg accattaact gattacaacc aattatatga agcgcagttc acgcagctat
    14821 atggaccgga taaagacggt tatatgattt ttaaagtaga atatccggat tatccagatg
    14881 taccacaaac acaaactcag gaaaatcagc tagtcgtaca gtaataggct agctgagaat
    14941 aatcctgaaa tattagtaga aaggagagtg aagataattc aagcaatcgt acaaaaattt
    15001 gtcaacaaaa tgagtgtcgg tttcttgctt ttgttgctga cgctagtctt ttttgtttgg
    15061 acagcagggg taggttttcc agcaactttg tttatatata acaatagttc attacttatc
    15121 gcttttagtg tggctatttt gctcatttta aatgtttata aagcaaaagg cgtcgatttt
    15181 ctttatctag gtgttgcgct tgcccttttc attttctttt cttactttcg ggaattaaga
    15241 aatgagtctt tatttggaga cttactgttt cctttgatta ttttattttg tttagtaatt
    15301 aaatggatcg agtggacaaa atgggatcgc ggtatttatc tgattgtctt tacggtcttc
    15361 ctcggaatca cgttatatcg tgtatttaca gagatccaag taccagaagg acaaagcatc
    15421 tgggctccag gcaattcgct ttctgatatt tggatcaata cgaatacaat cggaagttct
    15481 ttgatgactc ttgctttatt gatcagtgga tttgccagtt cttttgaacg atggtatgtt
    15541 cgaatcatcg gtgggatagc agtcgttgca gcctttttag gtatttgggt ctgccaatct
    15601 agaggtgcat tagtcgcgtt gattgttttt gcgatattgg atcttttacc taaatcgttg
    15661 atgcgtgtca ttcgtgcgcc atttattgcc tacacggtta cgattctttt agctttgccg
    15721 atttcttatc tggcggctgt ctctgaaaaa gtcaatttgt ttaccggtcg agaagatatt
    15781 tggcataaat tctatcagac gctaggagaa aaatctgaac aagttttact aggaatgaaa
    15841 acatttatct tccagcgagg aaaccaattt ttaggaaacc acaatagtta taattctatt
    15901 ttgaatatct atggattgat aggatttggg attgctgctt tgctgcttat cctttttatt
    15961 ggtcgcttaa cgttgaaagc agatttatcc aacgggcaga tgacttttat ctgggccttt
    16021 tttgcggtga tgatgcagtc atttatggag gatacattga cttcataccg atgggttccg
    16081 attatttata tcctgttggc tatggccgtt catcgatatg atgaaccaga agttacggag
    16141 gaattctatg ttatggaaga ggcatatgac gatatgactt atgatgatac atcttatgag
    16201 gaacaaccag atagcgctca ttcttccagg atccaacgct atcattgata ggcacaaaat
    16261 acgagagagg ctgtgacaac cgtcgcagcc ttttttggtt tattgcaatt gtctagcatc
    16321 ttctgtaaaa tagaaacgtt agagaaaatc ttgtatcata gaaaattaag aaagaaataa
    16381 gaacgcagct cggtaccaaa aatatggtaa aatggcactt gactgtaatt cactgaaaat
    16441 cgcttggagg aacacaaatg tttaaagatt tgtatttatt tatgaaggac atttatcaga
    16501 acagaaaatt actgctacag ttttcgatca atgacttcaa atcaagatat gcaggatcgt
    16561 ttttaggaat cttatgggcg tttatcaatc cgctatttac tgtattgatt tattggctgg
    16621 tatttggtgt tggactgaaa gcacaaatga tcgatgcaaa atacccattt atcgtatatt
    16681 tagttaccgg gatgattccc tggttcttct tctcagatgc atttgcatca actacggttg
    16741 tttttcggga atatacttat ttagtaaaga aagtcgtatt caatattcgt atcttgccca
    16801 cgacgaaaat cctatccaat ctgtacaccc atttattctt cattctgatt ggcatagctg
    16861 tcgcgcttat aaatggtata tatccttcag caatgtcttt acagctgatt tattatttat
    16921 tttgcatgtg tgctttcttg acaggattga cttggctgac ggcatcgatc caaccatttt
    16981 tacctgatat catgcaatta attacgatcg tgctgcagtt gatcatgtgg acattaccga
    17041 tattatggag ccctaatcag tttgattcag gtcttgtaag catattgaaa ttaaatccgc
    17101 tgtactatgt tgttcaaggt tatcgtgagt catttttaag tgaagcttgg ttctgggagc
    17161 atggaacata tactttgtat ttctgggttt tcacgttagt aatgttcgta atcggctctg
    17221 cagtgttccg tagattgaaa ccacattttt cagatgtgct gtaaggagaa tagctatgac
    17281 agaatatgca attagactaa aagatatcac aaaatcttat aatatgtacg caaaaccttc
    17341 ggatcgattt cgtgaagccc tcaatccttt taagaaatcc tatcatgatg tattttatgc
    17401 gttgaaaaac gtgaatgtag aaataaaaaa aggtgagatg atcggtttcg tgggagaaaa
    17461 cggatcggga aaatctacaa tgttgaaaat cattacggga gtactgacac caacatccgg
    17521 cacgatggaa atcgaaggaa aaatctcagc tttgctagaa ctaggatcag gattcaatcc
    17581 tgagtattct ggctatgaaa atatctattt aaatggaatg gttctaggat tttcaagaga
    17641 agaagtcgat gaaatggtcg atgatatcat tgaatttgct gacatcggcg accatattta
    17701 tcaacctgta aaaacctatt caagtgggat gttcgttcgt ctagcttttg ctgtagcgat
    17761 caatgtgaat cctgatattt tgattgtgga tgaagcattg gcagtaggag atcttgaatt
    17821 tcaactaaaa tgtatggaaa aatttacaga aatcaagaac tcgggaaaga cgattttatt
    17881 cgtttctcat gatattagtt cgattcgccg tttttgtgat cgttcctatt ggttgaaaaa
    17941 tggaaaagtt gtcgaatatg gtgatacgat ggaagtaacg acgaattacg aaaacttttt
    18001 gaagaaaaaa tcagttaaaa cagtagatcg aaataaaaac caagtagaac gcttcgcagc
    18061 tccagatatc gtagacgtga cgaaagccga attgttggat aaagataaaa atccagtgga
    18121 tatgctggaa caaggagaaa aactatacgt taaagtaacc tatgaagtaa aagacgatac
    18181 aatcaaaaat ccagttttag gaattgctct gcgtacagtc gacaattttt atgtgtgcgg
    18241 actcaatact ctactagatg gtatcaagat cccttggaaa aaaggtgaga atatctttta
    18301 tctggagtat gaaaagttag gtttgttagc tggtgaatat tattttgacg ttgcggtctt
    18361 tgaagaaaat gcaacggttc ctttggtata caagacaaaa tacatgaact tgtttgtcag
    18421 cggttcttat atcggagaag gcatcgtggt cttagaccat aaatgggaag aagggactca
    18481 tagcaatgaa atatgatttt gaaatggacc tagatgaaca aagcagtgtg ggaaaaattg
    18541 ccgcacagat caaaccagga agtaaagttt tagagtttgg tcctggaaac ggccgattaa
    18601 cgaaacattt gatcggagca aaacaatgtg aagtgagcat tgtcgagcta gataaggaat
    18661 tgttcgattt tgtcagcgag tttgcccaag atggatttta tggagatatc gaaagttttg
    18721 aatgggcaaa ctattatgct ggacaaacat ttgattacgt tttgtttgcc gatgttttag
    18781 aacatttggt agatcctgga aaaacgttga agaaagttag agaatttttg aatgaagaag
    18841 gagaaattct aattacattc cctaaccttg cgcataattc tgtcatgatt gatttgttca
    18901 ataatcaatt gccatgggct tcttatggtt tgctagatga aacccataat tctttttata
    18961 ctcatgatgg cttccaaaaa gtttttgaaa aagcaggatt atacatcaat attgaagatt
    19021 atttgtactt agctgtaggt gatacagaat taaaatcaac ttatgaagaa ttgccggaag
    19081 ctgtacgtta tgatttcaaa atgcgaccat ttggcgaagt ctaccaatac ttcttctcat
    19141 tgatgaaaca tccagtagca caaagttcca ttgcgcagcc gcaaaattct aattatgtga
    19201 aagtattaga agtaatccag caaacgaaac aagatgaaat aattcaacaa ataccattca
    19261 ataatttcac aggggaaaat gagacactaa gtttccatgt atcagaatta gcagaacgaa
    19321 tggtgtttcg cttcgcgcag caacctagct ttatcgaatt cagcgcagaa gctgctggag
    19381 aaaaactcac atttatcgat tcaaatgctg tagtcaaaac agtaaatgat tgttatttgt
    19441 ttgatggtaa agatttacca gagttctttt taacggatat tgcagggaaa gaagtgacta
    19501 tccattgtca ctatcgtttt atcggagaat tgacaccaac aatgaaagaa ttgctggaaa
    19561 caatccgtcc aatggctgaa gttacaaagc agctttctga gaaaaatgat gaattagaaa
    19621 gagaaaatca ttatcttatt gagaataata caagattaga tcagacgttg aaaacaacca
    19681 taaatcgcta ttgcacgttg ttggaaagtg atgaatggac aatcaaacat agattagggc
    19741 gacgtaagaa agaaacatcg aaaaaaatcc aagaaaaaga gctttctcta tgtattgacg
    19801 aaaaaatctg ggatgcagaa acaaagatat tgaaaatcat cgggtgggga atcgctaatt
    19861 cggatcgcca accattgtcc tataagttat cagccgacca atcaccattt tttgaagcaa
    19921 ttcctgtttt acgagaagaa gtcaatcaag caaaacagct agctgaagga gcaaaagcag
    19981 gatttgaact gcggatcctt tgcgagaagg aacgttcatt cttagttgaa gcagtggctc
    20041 aaaatggtca atcatggatc attgaaatgt aaataatgat taacttataa agataaggag
    20101 taaacgaatc gtgcaaaaaa aagaaattgc cgtatttatc gatcaaatca ctcgtgaacg
    20161 ggccactggc gatttgctta ttgtgggctg ggcaattgat gaagtgacca aagaaatccc
    20221 tacgataaag gtagaaaaag aaaatgtgat tgctgaagca acacatgtcg taagattgga
    20281 tatcaatcat ttatataatc ttgatgttaa gacccaaagc ggttttaagg tacgtttatc
    20341 agggaaaatg agaggaaaag caatcttaga cttccaaaca gcaagacatc aaaatggcat
    20401 agctgtgaaa ttaaacggta aatatcctta tgatgacggc attgaatctt catgggaaag
    20461 aaaaaaaaga ttactgaaaa aagggataaa ttatgcaagg actcatggcg taaaaaaagc
    20521 aatccgccgg gtcaaactgg aattgaaacc aggatcgatc gactatgcag agtggatcag
    20581 tcgtcatgag aaacctgatc tgaaagagca aaggaaagaa gtacaaggat ttgcctaccg
    20641 cccattgatt tccatactta tgcctgtcta taacgttgaa atcaaatggc tcgaaaaatg
    20701 cattgattcg gtacttgatc aaacgtatga tcactgggaa ctatgtatca gtgatgatgc
    20761 ttctactgat ccagctatcc gaaagtgtct agaatcctat caagcaaaag atgatagaat
    20821 taaagtcgtt ttccgacaag aaaatggaca catcagtctg gcaactaatt ctgcattgga
    20881 aatggcagaa ggagagttta tagcgctctt agataatgat gacgaattac ctccatttgc
    20941 cttatatgaa gtggcaaaag tgctaaacgt acatccagaa ctggatttga tctacagtga
    21001 cgaagataaa atcgatgcag atgggaatcg ctttgacccg cacttcaaag cagactggtc
    21061 tcccgataca ttgatgggaa ataattatat ctctcactta ggcgtatatc ggacaagcat
    21121 tgttaaggaa cttggcggtt tccgtaaagg atatgaaggc tctcaagatt atgatttggt
    21181 tcttcgtgtg acagaacaaa ttcctgcaga acacatttac cacattgacc gtgtcttgta
    21241 tcattggcgg acgatcccgg gatcaactgc aagcaatgga gaagctaaaa gctacatcta
    21301 tgattctgga gtgaaagcat tgacagatgc tctatctaga agaaatatca agggaagcgt
    21361 acatcctggc agaatttctg gtttttatga aatcacttat gatgttttgc aagaagactt
    21421 ggtcagtgtg atcattccaa ctaagaatgg ctatgaagat ctaaaaactt gtgtggattc
    21481 gatcatcgaa aaaacgtctt atccaaatta tgaaatcatt attgcagata atggaagtac
    21541 agatcctaaa atgcaagaat tatttgcaga atacaagcat cagctgaaag accgatttat
    21601 cgtcgaatta attgacattc cattcaatta ttcacgtatc aacaatctgg cagcagaaaa
    21661 agcaaacggc aaatactttt tattcttgaa taacgataca gaagtgattg aacctgactg
    21721 gatgacagcg atggtttctt atgcacagtt tgatcgaatc ggctgtgtag gagcaaaatt
    21781 attttatccg gatgatacaa cgcagcatgc aggtgtatta ttagggatcg gtggcgttgc
    21841 aggacatgca ttgaataact atgatcgaac acattgtggt tactttggcc gattggtcat
    21901 tgacgtcaat tacttagcag tcactgcagc ttgtatgatg gtcaaggcag ctgacttcaa
    21961 tgctgtcaat ggatttgatg aaatattaga agtagcattc aacgatgttg acttgtgctt
    22021 gaaagtttat gaactgggtc gttacaatgt ctatgcacat caagcagaat tgtaccattt
    22081 cgaatctaaa tcaagaggtt atgaagatac accagaaaaa caaagacgtt ttgctgggga
    22141 aatcaaaaaa atgcaagata agtggccttc ttatattgct catgacccat tttataacga
    22201 taatctaact aaagaaggaa tcggcgattt ttcgttgaga cctgattgat taaaagaact
    22261 gtattttcat ttttattaat gaaaatacag ttcttttaat ttaatt
//
LOCUS       DACGMI010000049        21757 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.050, whole genome shotgun sequence.
ACCESSION   DACGMI010000049 DACGMI010000000
VERSION     DACGMI010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21757
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.050"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(61..279)
                     /locus_tag="IXT46_002087"
                     /pseudo
     CDS             complement(61..279)
                     /locus_tag="IXT46_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(545..739)
                     /locus_tag="IXT46_002088"
     CDS             complement(545..739)
                     /locus_tag="IXT46_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947989.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            2091..3131
                     /locus_tag="IXT46_002089"
     CDS             2091..3131
                     /locus_tag="IXT46_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HAQ4947990.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SSPSTITKDWLE"
     gene            3972..4304
                     /locus_tag="IXT46_002090"
     CDS             3972..4304
                     /locus_tag="IXT46_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAQ4947991.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            4923..5264
                     /locus_tag="IXT46_002091"
     CDS             4923..5264
                     /locus_tag="IXT46_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAQ4947992.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     NEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            5283..5573
                     /locus_tag="IXT46_002092"
     CDS             5283..5573
                     /locus_tag="IXT46_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947993.1"
                     /translation="MKFFEVKSPYYYALIAAKNEEECAELYEQVVTDIENREEFIRCL
                     HELNRNEAIQEDAKKISEETLQPIGMEEATKDIFTIIDEQKSCVLSIDSTLV"
     gene            5765..5998
                     /locus_tag="IXT46_002093"
     CDS             5765..5998
                     /locus_tag="IXT46_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947994.1"
                     /translation="MARPVLDAMDMDTLTKGRYVQLLARGYSPKDVFKALSKGTDMEK
                     ERLRKEFDYWREHNGIKDLKPARPVIRRKKLKK"
     gene            6404..7075
                     /locus_tag="IXT46_002094"
     CDS             6404..7075
                     /locus_tag="IXT46_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAQ4947995.1"
                     /translation="MKKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPID
                     QINEHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQAFAQIQIPALGLTLPIFK
                     GANQYTLSLGAATYFYEDAEMRKGNYVLAGHNMEIPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            7128..9107
                     /locus_tag="IXT46_002095"
     CDS             7128..9107
                     /locus_tag="IXT46_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAQ4947996.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDVDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQAL
                     PREDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNNS
                     KGNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELT
                     KFGDDGTAQSKQTPLKGAKFGLYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVE
                     VPSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVID
                     KTVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDT
                     AGQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASL
                     HGQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLK
                     VDSGLFGTGIKATPLESAEFAAKNAEGKYYGGLVDTDKNGVKEAVWVDDVANAAILKS
                     DKEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKAS
                     VPMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            9122..9874
                     /locus_tag="IXT46_002096"
     CDS             9122..9874
                     /locus_tag="IXT46_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4947997.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWTWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            9890..10651
                     /locus_tag="IXT46_002097"
     CDS             9890..10651
                     /locus_tag="IXT46_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947998.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLFSDQLKLVSNGKTKTIDQQT
                     GVFEFSIEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            10664..10924
                     /locus_tag="IXT46_002098"
     CDS             10664..10924
                     /locus_tag="IXT46_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4947999.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            10921..13011
                     /locus_tag="IXT46_002099"
     CDS             10921..13011
                     /locus_tag="IXT46_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAQ4948000.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKTTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            13038..13502
                     /locus_tag="IXT46_002100"
     CDS             13038..13502
                     /locus_tag="IXT46_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948001.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            13499..13741
                     /locus_tag="IXT46_002101"
     CDS             13499..13741
                     /locus_tag="IXT46_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948002.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            13759..14061
                     /locus_tag="IXT46_002102"
     CDS             13759..14061
                     /locus_tag="IXT46_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948003.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            14131..16194
                     /locus_tag="IXT46_002103"
     CDS             14131..16194
                     /locus_tag="IXT46_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948004.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHEGRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYSTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEKENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHEIAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTQTNQEALSKEKENLLKERIRERKEEFYQGLRTDKLKISKELNEQLNKLYQIT
                     SEALMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEE
                     AQEQARKEYEQQLEELLNRTNQATTESSMENSKESDPSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            16194..18803
                     /locus_tag="IXT46_002104"
     CDS             16194..18803
                     /locus_tag="IXT46_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAQ4948005.1"
                     /translation="MRVRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAILMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGGFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYQDPENDYRQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNIL
                     STAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHQGKK
                     FHEERVKVGYRGFCEINFDCHLEQGDHVCLKYDHQGKEYVAWYEFSQRVLKDEEGNIV
                     YRKKRGETHLPELEKEAVLTLDEDKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHII
                     VSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLW
                     DLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENST
                     TNSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNHG
                     ETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDIYARRLYHNMH
                     DQIEEEAKENIFIKIVQSLDNSTAQKLLIQFYEEKQIDRLQEYLEKLHQNEEITEVIR
                     KRLLLEAEKAVKE"
     gene            18800..21196
                     /locus_tag="IXT46_002105"
     CDS             18800..21196
                     /locus_tag="IXT46_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948006.1"
                     /translation="MIIGGIFSGIANWWSGLFGDGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLETDPNKVESLPTDKRNALTAKNFKTANINSVII
                     PKEAAKMADEDKSGLSDIQKDRLRALQYRLELDDNGKEIPVEISDEGLAKYVYTSGYR
                     RYISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSNLNDIRKNGF
                     GNRKDVIPDNGEEQPDDKATIVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQY
                     RYKSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSMKIGLPKTQNLP
                     MKDSRLNQFKENDQSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNVSIQN
                     VVTREAAPEPIQKVHTGYKPANVAFTAPTKINVTRETKNRNNELKEQLLRDIKQDIKP
                     "
     gene            21248..21580
                     /locus_tag="IXT46_002106"
     CDS             21248..21580
                     /locus_tag="IXT46_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948007.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
BASE COUNT         8028 a         3275 c         4208 g         6246 t
ORIGIN      
        1 aggtattttt attatatata gatttaacat atgtcggtcg gttgattgat atagctaaag
       61 ttataactca accgaagccg attcatctac acgaataaag ttgcgagtgt tctcggctaa
      121 ttcataaaaa ttgttatgtg ttccatatag caatactgga ataactttat tttcttgaat
      181 ctcataagca actctataca cggtgaccgc atacttaaat ccattagacc aattacctga
      241 taaacctcca gttttttgct cttacttaaa tggatcaatg gcaatttcat cacaaaccta
      301 tagaggatga gtgacttctg cctaattacg ttaaaaaata ttgaaagtaa ctctatgtag
      361 caaaaaatat ctagaatttc atttcctcaa aactgatcga tattgtatct aaaaatatat
      421 actacctaaa ataggtagta tatattaaaa tatgtgcttt tgttagaaaa atcaatacat
      481 aaattatcat atctgtatat gtcatttagg tatttcagtt atgttataat agttttgctg
      541 tctgctaccc cggcctaatc tggcaagggg aggaggagat ataatgaaat acctttttga
      601 ttttgttttt gcaatcaagc cacttgcaga tgtagtgtgc agttacctct gcaaatggct
      661 tgattgcaaa attgccaaaa aagacagtaa gcctacccgt taattctata atatagaaac
      721 gtaaaaaaaa ccccatcagc ctgcacgctg atggggtttg gtgatataat gaaatacctc
      781 tttgttactc ataattatac cataattagt cacgaatgca accaatagaa aaaactactt
      841 agaacggtag atcatcgcta ataacaatgc attgtccacc aaatggattt tgtgaagcat
      901 taaatacatt gttattaatt gtcgctgctt ttaactaggc ctctcccctt ctattataaa
      961 agaagatata tatcatttct taattaccta ctaccttaaa ccaaaattta agtactacct
     1021 aatttaagta gtacttaaac aatctaaaaa atagttatcc caattgttat gcttttataa
     1081 tacgattatt tgtaacaaaa tgaatattat ataattaaac actaccatat ttaggtagtg
     1141 tttaattatt agcaaaacaa aaaatattta ttctattctc ttaacttcaa ctaagttatg
     1201 ctgcacacct ttatataaat catatgcaac tcattagcta gacaaactac aagcatgtag
     1261 ttttatctgt taattatgta ctacctaaat aaagtagttt ataattagca agtatatata
     1321 tttaaaaatt taagattaat ttttttatga cttgtacaaa tttatctgat attctcttat
     1381 taagaactac ctaatttggg tagttcttat tttttacatt ttaagtagta tttaattgca
     1441 atttggtagt atttttttat tatcttattc ttagaacggt agtacttaat ataaatatag
     1501 gtagtatcta atttaagtat taatggtagt atctaaatta acaggtagta tgtaactact
     1561 ttaaagtaat ttttttcaga ttaacacagt agtatcttat taaataagtt aattttaatg
     1621 gtagtacata attattatat atatctaaca ttggtagtac ttattgtatt ttttagtagt
     1681 atataatcta ttgttttcta gcctaaagcc ttgtcttata agaataatat aatatatact
     1741 actgaaataa ggtagtatat attactagta gtggtagtat gttttatatg cataaggtag
     1801 ttcttaattt attttttgtt ttgatactgg tagtacttaa ttatccttaa ttttaaaacc
     1861 aaattttatt catacgttct tctggtagta tttaattata aataatattt atttaaagta
     1921 gttcttaatg actttaaagg tagtacataa ttcattttat ttcttatttt aggtagtatt
     1981 taattaaaaa acagttttaa tgcgtttgca ttttttattt atctttgcta ttttcgaaaa
     2041 gagtaggtaa ttttacataa ataaaacaac gtgaaagtag aggatctaca atgactgatt
     2101 ttaatttttt taaggcggat agagtttaca acgaattatt ttatcaattt ccaaaagtct
     2161 ttattgtttc tgacgaatac aaaaaaatga aagattcaac taagattgcc tatatgcttt
     2221 taaaagcaag attagagatc gcaatcagca aacggcaaat cgatgaagaa ggtaatgttt
     2281 attttactta tacgacaaat gaactatgta gcgtattaaa ctgccaaaaa caaaaagcga
     2341 tagcaatcaa aaaagagttg gaatcctttg gtttattatt acaaaagcag atgggattta
     2401 acaaacagtt agggaaaaat aatcctaata gactatatct agcagaatta aaagtctcag
     2461 aaaatgatat ctacttactc gaaaaatttg atagagagaa tagggaaaat gttgataaat
     2521 cagagggtat gaaaatcata cccaccctcg acgaaaaatc agacgctgaa tcccttgggg
     2581 ctcaagaggg tatgaaaatc ataccgtgcc aaaacgttga taaatcagag ggtatgaaaa
     2641 tcataccaga acttaataat aatatattag acactaatag acacaatata gacactgaaa
     2701 aagaccgcct acaagatcaa ttgttgttag acaattttga gacaattatg acaaacgaca
     2761 gcattgctac gtttgtccct gaacgagtat taaatttgat aaaaacattt tcttcaagtt
     2821 acagtgaagc tcaaaaaacc gtccagacta ttcataatgc aaagaaaaaa gctgaaatag
     2881 aaagtggtat ttcgatagtt tttgaagaac tcgatagtta ttatgtcaat gcagaacaag
     2941 aattatacac gacactgtta aaagcctatc aaaaattaaa aaccgaaaaa gtcgaaaata
     3001 tccagaacct gatttttgtc tatgtaaaaa attggtttat cgaaaaacca atagctgcta
     3061 aagtatcaag tgaaaaacgt ttgaattctg aaagctcccc aagcactatt acgaaagact
     3121 ggttagagtg aaactttact gacaaagtga ttgttgcttc atggagtaac attaaagtta
     3181 aaaatttttt attattctaa ttatattacg aatattacaa aataatagct attttaatag
     3241 aatttataag ttaaaatatt atgataaaaa tcacaaacgt agccttttac gtcataagtg
     3301 ttaaaagaaa taattaattt caaatataaa aaagggaacg tatgtttgca tactcctttt
     3361 ttttgagtta taataatacg cgaagagaga taatttcatt atttaaacaa actaaaaatc
     3421 ttgatattac ttcttttcag gcaatacgaa tattattcgc ttacattttt ttgtataaat
     3481 ttagttgttt taaatttaat tgtctgctat gcctgtgatg aattgatttt cgttctgcac
     3541 ttttggacga taaatttgga caattgaaaa tacaaaaaaa aagaaaggcg gtatgaactc
     3601 ggaaggctgg taaccttcgt cagcgttcat acacggcatt aagatttggc ccttaatgcg
     3661 ttaacctttc agtgttacgg tattacccgc aatggattta gtataacaga tattcaaaag
     3721 tgataccact ttttttggct gtgttaaggt taaaaatacg tgatattacg atgaatctat
     3781 gcctaagcat aatgttataa aaatgtccgt gtggctcttt gccgtatgac gaacgctgaa
     3841 attagaggga acgcatgttt ggatgcgttc cctctttttt gtttgtcatg aacgaaaatc
     3901 aattctctat ttttgaaaaa taacaagaaa aacttgttaa aaatatttaa agaaattggg
     3961 tggtttattt tatgtcatat acaggaattt tgagtctcaa agatatttgt cactacggta
     4021 aacggtgtac cgctacagag aaaatcacga agaaactatc aactggccaa agtaaaaccg
     4081 ttgtgcagtg taagaaatat ataatccaga aagacaaagt ctcagaggaa atgatttatt
     4141 acattgggaa acaaaagcaa ataattttaa aagatcctat ccccttaaaa gagctatatc
     4201 caacaatcaa acatgtttat gaccaaaacg gtgtactgat tggtcgaaga aaaaatggag
     4261 tcttgcgttg taccgcaaaa gggatggggc gtttaatcag ctgaattgat cattctcata
     4321 acttgtattt tatcgttttt cgcttgcttg aaaatattgt cgagacttct aaaagaactt
     4381 agaatcatta gaaaaataag gagtagactt gatctatcaa caatttcctt cggggagtga
     4441 cggggtagat ttttacgatt ggtaacgtaa aaaattggtc aatcgagtaa atgcgcttgt
     4501 ttggatagtg gtgaaatgaa tttgtgtaaa taatatacac agagtaaaca agagggaatt
     4561 tagaggttag acaagttaga atagcgccta gattaatcat gagcagctac taagggatct
     4621 aggctttgac gcaaactcat ggaataagga gtaggtcttc tcgtaatggg gaggacgcac
     4681 aagaaattgt gtcgtgtgct gcagtacatg tagatacttg cgaggacgtt ggtcattggg
     4741 tcaatcgagc atttaccgct gtctactagg gtttctcgtt tcggacgcca taaacgagtc
     4801 gatatttttt atgtattttt aagtaaacga aaaacgataa aatatgaacg agtcctgaat
     4861 aaagtgaaaa aattgatata aaacatagag aaaatgaaat ttacgtaatg gaggaatgac
     4921 aaatgaaaaa ttatgatccg aatatacgat tgggcacaca tactattaag gtttctttcc
     4981 aacgttggga ttacaaaggt tttgtgacgt ttagaagagg cggaaattgt aaaggattag
     5041 atgttttagc attaaacgag gatgatttat acgatcaaac attgactgat aatccaattg
     5101 gattcggctt gctacctgaa gatgatgaag gtaatgaatg gtttaaaatg acgcttatga
     5161 atgataatgg agacgaatta tctgttgaag atacttggtc atatttgagt gattatattg
     5221 tcagcgttga aatcattgaa tttgtagcgg ataaagaaga ataaaaactg gaggaataaa
     5281 ttatgaaatt tttcgaagta aaatcaccat actattatgc gttaatcgca gcaaagaatg
     5341 aagaagaatg tgcagaattg tatgaacaag tagtaacaga tatcgaaaat cgtgaagaat
     5401 ttattcgatg tttgcatgag ttaaatcgaa atgaagcaat tcaagaggat gcgaaaaaaa
     5461 ttagtgaaga aacgttacaa ccaatcggta tggaggaagc tacaaaagac atttttacaa
     5521 ttattgatga acaaaaatct tgtgtattaa gcattgattc tacattggtt taatagatcc
     5581 aagattctat aatttttttc aaagtaaaaa gaaattaggt aatgattctc agaccaatta
     5641 cttaggaaaa taaccataca aattagattt tacagataaa ggattagaag gaatcacggc
     5701 gattaataaa aaggtagtat taccttaggc attgagtaag gaatttattt aggaggaaaa
     5761 ttagatggcg cgaccagttt tagatgcgat ggatatggat actttgacaa aaggaaggta
     5821 tgtacagctg ttagctcgtg gttattcacc taaagatgta ttcaaagccc tatctaaagg
     5881 aacagatatg gaaaaagaaa gattacgaaa agaattcgac tattggagag agcataacgg
     5941 aataaaagat ttaaaaccag cacgtccagt tattagacga aaaaaattga agaagtaaga
     6001 ccaaagcgta tggcgtacat aggctttttt attttgataa aaataatgaa aggaaggaaa
     6061 actcatgaat tgtaaagaaa tcgaaaatag aaaaaaagtg tcgaaagaaa tggaagaaaa
     6121 gttactaaaa acaatgaaac aaaaacaatg aaacaaaaac accttaaaag attatctgtc
     6181 gcgcaatata tcaatgatat gcagttaaca ggaaaagaga aagcttgttt gttaggttca
     6241 atgaaaaact ttgaacagtt gagacgaact tatgtgaaaa aaagttctaa ttgtcaacta
     6301 ttgttagaag tctcatgaca ttcattaata gaattcattt ttaaaacttt ttctatggaa
     6361 atgagaaaaa gtttttttgt tttgtctgaa aggaggcaga tggatgaaaa aatggttatt
     6421 tggtttttta ggagtcgctt taatcgtctt ttgcagtgtg tttggctatg ttagctacca
     6481 aaaacatgaa ggagaggtgt ttaagcaaaa tatagaaaaa aagatgccca tagatcaaat
     6541 caatgaacat gcaaagagtt ataaggagga tgcaacgaac gttaataatg atatgtcttt
     6601 gggacaaatg ttgtccatac aaaaagaagc aatcgaaatg ggcgtcaata aacaagcctt
     6661 tgcacaaatt cagattcctg cgcttggttt aacattgccg atttttaaag gtgcaaatca
     6721 atacacattg agtcttggtg cggctactta tttttatgag gatgccgaaa tgcgcaaagg
     6781 aaactatgtt ctagcaggtc ataacatgga aattccaggt gttttatttt ctgatattca
     6841 aaagttgtca ctaggggagg tgatggactt agttagtaac gatggcgtct atcgttacaa
     6901 ggtaacgcgt aaatttatcg tacctgagta ctttaaatta atcgatggcg ttcctgaaga
     6961 gaactctttc ttgtctttac caaagaaagg agagaaaccc ttattaacgt tgtttacttg
     7021 tgtttatacg tcacaaggaa aagaaagata cgtggtacag ggagagctac aataacaagg
     7081 ttttaatcaa cgtgagtcgt tgaaatatga aacgaggaga gtaaaaaatg gcaataaatc
     7141 ggtatgtaaa aaaagctgga atgcttgttg gaatgttagg aatcattgca ggctgctttc
     7201 agggatatcg agcatatgca gaagatgtca cgcaaaaaac gccaccagag aaggtcaata
     7261 tcacggttca taaattaatg tatgatcaag gaacgcaatt gaatgttgat gttgacggga
     7321 tcaaaaacga tggttatacg cacgatcaat atcctacggg tgtaacgaaa tacaacaagg
     7381 cagattatgg tgatgttgag tttacgttag gaaatattac ggatcaagca ttaccgaggg
     7441 aagattctga tctaaccaac gcgaaagtgg acgaaatcgt taaagatgta gaagacaagg
     7501 gatctaacag tgagtacgtc aagaatgcaa ccaacaaaat tacttcagct gtagatgaaa
     7561 atggtgagat tacttttgct gatcaaccag cctatgtcaa caattccaaa gggaatgtat
     7621 atgtggttta tgaaagtaaa tccgctgctg gattagtcac acaaaaagca aaaccaatgg
     7681 ttgtgattgc gccaatgact gataatacag gttcaggttt tttaaaagac attcacttat
     7741 atcctaaaaa tattgtttct aagttgagtt ttgaattaac gaaatttggt gacgatggca
     7801 cagctcaaag caaacaaaca cctttaaaag gggcaaaatt tgggttatac aagggcgaac
     7861 ctggaaaagg aacaaaatta ggagatcttg tatcggatga tcaaggaaag ctgactgcta
     7921 ctgatttgac gttaggaaaa tactattttg tggaagttcc ttcagaagtt gtagtgggat
     7981 cagataaaga accaacagcc gatcaatatt tattaggcgc agacgctcgc aacgatgcgc
     8041 acaataaatt aacctttgaa attacgaatg atggcgtgac aagtgactta aaagcttcat
     8101 acgtaaacta taaagcacca gtgatcgata aaacagtaac aaatggaaca ggacaagaac
     8161 attctttcca aattggtgac gcagtaaatt atcaaggaac gattcatatc ccaacagaca
     8221 ttgcaggcgg agcagacggt atcacagtaa acggagtgaa aagcgaaact tctccttaca
     8281 gtgtatttaa atggggggat acagcaggac aaggactttc ttatgtcgct gctaaagcaa
     8341 atatcaaagt aacaaataaa gatggatctg tggtattaaa agaaaataca gattataaaa
     8401 tccaaaattc agaaaatggc tttgtgatcg attttatcgt gaataatggc caagtaagtg
     8461 atactgtagc aagtttacac ggacaagatc ttcaaatgac ttataacatg tatgtaaatg
     8521 acagcgcagc tgttgccaat ccattaacaa atagcgtgga tttcgtttat aacaacaatc
     8581 catttaatca ggaagaacac cacgaaaaaa cgaaagctga cgttgtgact tatggtgcaa
     8641 aattcttaaa agtcgatagc ggactatttg gaacaggaat caaagcaaca ccgcttgaaa
     8701 gcgcagaatt tgctgctaaa aacgcagaag gaaaatatta tggtggatta gttgatacgg
     8761 ataaaaacgg tgtcaaagaa gcagtatggg tagacgatgt agcaaatgca gcgatcctaa
     8821 aatcagataa agaaggtcac tttgaaatca ctggtttaac tgaaggtgaa tattcactgg
     8881 aagaaacaaa agcgcctgaa aactatcaaa aattaacgaa agagatctct ttcaaagtag
     8941 acaaagattc atacaaagaa gaaaaccgaa ttacgatcaa aaacaatcaa aaagcttccg
     9001 taccaatgac cggtagcaac ggttttcaaa cgtatgtatt aatctcttgc ttgttgctag
     9061 gagcaggggc actttctgca gttgtttact ttaagaagaa agcctagaag gatcaaaacc
     9121 aatgattatc aggaagccta agaaaaagcg aatcatgggt aaatggatca ttgctttctg
     9181 gttactttca gctgtaggtg tcttactttt gatgcctgct gaagcgagcg tggcgaaata
     9241 ccaacaaaat cagcagattg ccgcaatcga tcgaacagga acggcagcag aaacggattc
     9301 ttctttggat gttgctaaga ttgagttagg cgatcctgtt ggtattctta caattccaag
     9361 tatttcttta aaactaccaa tttatgacgg aacgtccgac aaaattttag aaaatggtgt
     9421 aggtattacg gaaggaactg gtgatattac aggaggaaac ggtaaaaatc ctttaatcgc
     9481 aggtcatagt ggactttata aagataatct ttttgatgat ttaccttcag taaaaaaggg
     9541 agaaaagttt tatatcaaag ttgatggtga gcagcacgct tatcaaatcg atcggattga
     9601 ggaagtgcaa aaagacgaac tacaaagaaa ctttgtcact tacttagaac caaatcccaa
     9661 tgaagatcga gtaacgctaa tgacatgtac gcctaagggg atcaacacac accgttttct
     9721 agtgtatggg aagcgagtaa cctttacaaa atcagaatta aaagatgaag aaaataagaa
     9781 acaaaaatta tcttggacat ggcttttagg aagtactgtt tttctttcag tcatgatcat
     9841 tggttcgcta tttgtttata aaaagaaaaa ataaaggagg gtaaccaaca tgagaaatag
     9901 aaaatggcta tttgtttgtg cagccgctct tttttctttc actgcctaca cacagttgac
     9961 gtttgcagac agacaagaaa gcacggatag cacagaacaa acaatccaaa cgtcagatag
    10021 cagcacgatt caaagcagcg atgaaaccgt cgattcgtca acagttgatt cttcagaaga
    10081 accgaaaatt gctgaagacg atcaaatagt caaacagacc attcacgttc aaaaaattat
    10141 ttcttccgaa caattagaca accaggggca aaaacttgaa aaacaagaag gagtaaatgg
    10201 cgcgaagttt tctgtttatg atgtatcgga cattttacaa aagatggatg ttaaggatct
    10261 cactactgac caaattgaat cccaattaaa agatcgagtg aaaaaactat tcagtgatca
    10321 attgaagcta gtttctaatg gaaaaacaaa gacaattgat caacaaacag gtgtctttga
    10381 attctcgata gaagtacagg caaatcagaa acaagcttat tatattgtca atgaatcaag
    10441 tcctgaaaac atttctaata gcgaggatat tttgctatta acacctgttt ctgataaaaa
    10501 cggtgaattc ttaaaggatg tgtggatcta tcctaaatca gaagcttcgc aacctaaaga
    10561 agaagtaaaa aaaatcgttt ctactggcgt aaagaaaaac ttctttgaga attgttggga
    10621 ttttgttact cacttgtttt ctagagatta aggaagaaat aaaatgaaac tgatcaaatt
    10681 attattattc aatttttctt gtttaaccgc agtctttttg tactgcggtt tattattttc
    10741 taaactatct attttgccaa gctaccaact atacctaatg aggattttaa acataccagc
    10801 tgcttccatg ccgctagata ttatggaaaa gctcattagg aatccattat ttactacgat
    10861 caatttgatc gttattgtcg gaatttcact agtcatttat aaaaaagagg ggatgaaggg
    10921 atgaatttta aacactcgtg gacaagacgg ttaaaatatg tttttcccat aatgatgatg
    10981 ttaggtacat tgtttgggtt aaaaacagcc aatgtctttg ctgaaaaagt tattgtcgat
    11041 ccgtcaaatc caatccagaa cgtaaagaat aattttatta ttccaaaaga tgttcctaat
    11101 gcaaaaacaa atattactgt aaacggagcg tcaaaagttt acaaatatca tgttgatgcc
    11161 aacaaaggtg gttttacaga cgactacgta ggattagtgg agggaaacaa aaatatacgc
    11221 tatccttctt tccaaaaaga atacggtgaa acaaaccttg ttttagaagg cgtaacaacc
    11281 aacaccaaag tcaatattga ctatggaaaa atcggtacgt ataacgggaa aaaagtcaat
    11341 atcaagctag ttctatctaa tattcactta tactcggata cgttgccgtg gaatctacta
    11401 gataacaact atacaaaaac tcattttcga gacgatggct ataaaaatac gaatggtgca
    11461 atgagtaaat ctaaaaaaag aacagtactt tggatctcag acaatctttt ctcaggaatt
    11521 gtttaccatt caacacaaat gaatgtgcag ctagtagcca catatgagga cggtagcccc
    11581 gttcaatttt caggagatac atttatcagt tttaactctt tgaaccctgc aggaggaaaa
    11641 accacggatc ttaaaggaga atatgcccac tatgacaaaa tgaatacgac agattggtat
    11701 gtcagaaaag atacggttct ttcagaattt aaatctttct acaacaatct gaacgtggta
    11761 ggtggccacc caggaggaag ctctaagctg acacaagcgg ataatgattt caataatttg
    11821 catgataaat taggagatcc gaagtttggt caaggtactg tgtcctttaa aatatctgaa
    11881 gcaaatccga cgtttgtgat tggttcttct aatgttcaaa cctggtttac tttatcttct
    11941 gcgacaatct ttagtgttgt tcctgatcaa cctgaaaaaa caggggttga taaaaatgga
    12001 aataacgtga acgataaaat gttgcaagta ggagacacga ttcaatatcg aatcaaacag
    12061 aaggtgaatc gattaggagt ggatttacta gcggtttacg atcgatttga gttaatcgat
    12121 aatttaccaa aagaagtaaa ttacgtcgat gcacacgttg aaagtggtac aaataaaaaa
    12181 ttcgatgtat ctggtgaagt gacctatgac aaaacaaaac accaggtaaa atatgcagcg
    12241 aaagctgata cattaaaaaa tcgaatgaag tataacggcg aaacttacga attagtgatc
    12301 aatgtaaaag tcaatgaatt ggccaatcaa aatagtgtag ccaaaaatca gggaacgtcg
    12361 atcattaata aagtagaaaa ggatacaaat atcattaccg tttatttccc taaaattcca
    12421 gtgaaagaag tacaacaaaa tggaaaagat gtaaacggac gaaatgacgg taagaagggt
    12481 acgccgacag ctcctttaaa cgcaggatct gaagtacaat atctagtcac acaaaaatgg
    12541 cacacaaaag gcgtagacgc tgcgtcagat cactacaaac aatttagtat tcaagatcca
    12601 attgaagctc gtttgacata taaagaaggt tctgcgcaag taatagataa gagtaaagga
    12661 aaagatatta cttctgaagg cacactaacc tatgatagca attcaagaac gctgaagtgg
    12721 gaagcttccg ctgacttctt aagtaacaat cttttagatg gacgagaaat tcagctgata
    12781 tttacagcta aaactccatt acaatcagaa aaaaatattg ataaccaagc cgtagtagca
    12841 gtagataatg tttctaataa aacaaatgtt gtgacaattg gggttgatcc taacttgcca
    12901 caggtcattg ttcctaaaac aggttctaca catttagtaa cgatttcagc ggtcagctta
    12961 ctattacttg tgttagcaac ttttagttat gcggttctga gatacattta aaataaaaaa
    13021 acgaaagaat gaataaaatg aaaaagttaa taatagtagt tacttccttg attgccatga
    13081 ttgttatttt agtcggatgt agtaatgaaa aaaataaaca aactaatcaa gataatggcg
    13141 tattgaaatc aggaactatg tggaaagaag aagtaggtgg tcttgtttat aatttgaaaa
    13201 ttatagacga gactacctgg gaatactctg agagtgtatg gcatccagat cctgtacaaa
    13261 taacagtcaa gaggcaaaaa gactataaag gtttagaaag atacaaaata gtagattcag
    13321 ctggtgttag ggaatttata aacaaatctg attctttatt tattgttgtt ccctatgaga
    13381 agaatggcgt aaaaaaaata atttttcttg gatctagcaa ggatgaaaag cgaacgaaag
    13441 agaaattgat tcacgatgga tcacaatcca ataaatataa gttacaaaag actagcgagt
    13501 gattgctagt ctttttattt gtcctgaagg aggaatcaca gtggcaaaag ctaaaacgcc
    13561 atttgaaaaa gccgcgtcta aaatcttaga acgccgcggt gtatctgaaa cacagtggaa
    13621 acaagaagtc cttgaaaaag cacaatttga cctattacgg ggaaaagaca aggacttaga
    13681 aggatatatc tatcaacgtg aacgtgaaaa gcttgttttc gacgaaatta ttaaacacta
    13741 aaaggagcga acaattttat gtttgaatca attacaatga attttttaac acaaccgaaa
    13801 gtagtagctg cggttgatat ttttagagca ttacaaactg ccgcaactag tttaaaaaac
    13861 aatctgatga tttttgctgc tgctgcggcc gttgcttcca ttgttattgg gggtcttttc
    13921 ttcctatttg gacgaagagg agctgaaaat gggaagatgc acgtaggcta tgtattgatg
    13981 ggggtaggag ttattttagc agcagcttct attgtggttt cgttatttgg attgtttgga
    14041 caaacacctc aaggattata agaaagtaaa aaagtaggag taagaagtag tcgatacttt
    14101 ttactccttt tttatgaaag gagaatactc atgtacttta cgattgcagg caataccaaa
    14161 acagataaag agttaataaa aaaagcaacg aaggaagtag gaaagcgtac ttctttttta
    14221 ccgaaaacaa ttaaatattc tgtcattgaa acggaagaac agctacatgt gttagggaaa
    14281 gtactggaac acgaaggtcg atcttctgtt aagttgactc tcacgttaca tgacacagaa
    14341 ggaaaaatag agaaagctgg tacagaatac gtttttggcc cactggatta tcaaatttca
    14401 gaaggtttct attctacatt gatggattta atccgccttg atgtgtttaa agaaacggat
    14461 gaaactatga gtgtggaaga gtcttatcga aacgaaaaac ttttacaagt tttagaagaa
    14521 gagttagaga gcgaccaaag aaaagtgaat caagggagtg aagtcgaagt aaatgaagaa
    14581 gtaccatggg aacgaccaat atttccaaag aaggagtcaa aagaaaaaga gacagtctat
    14641 gttgacgaac aagctgatat tccgactcag aaatcgatat ttgagaaaga gaacgatgtg
    14701 atgggtcagt tggaggtaga tccctttgaa gaaacaatgg aggatgaaga gacggccgaa
    14761 gtagaagttg atccagttga agctaatgaa gagtcaacat ggactgaagg ggattctcag
    14821 gaatatattg aaccacttat cagtgaagaa gtagaaaaaa acgaaataga gatacaaaag
    14881 gcaactgtat ttgattatat tttggatcaa tatccgccag agcatgaatg gatgaaagaa
    14941 aaaaacaaat tatttttaaa tgagctttat tcgaaatatc aattacccca aacctatcaa
    15001 gcatttttag agagtaaaga agaattaatc tcacagggta aaggcacact tttagaacag
    15061 ttagagtctg tccaatcaac aaattggcat gagattgcac aagaagattt attagccacc
    15121 tttgaagaac gtcaacaaga aacagatcaa gaaattaatg agtatgcgac ggaacagtcg
    15181 tctaattggg agaaagcaaa agaggaacta aataaagaag aacagcgagt gattgaagaa
    15241 gaagtacaaa aaattaaaga gcgatacgaa aagaaacgcg acaatgcgta ttccttgtgt
    15301 gtagaaaaga tcaataattt tactcagacg aatcaagaag cgttatcgaa agaaaaagaa
    15361 aacttgttaa aagaacgtat aagagaacga aaagaagaat tttatcaagg tttgcgtaca
    15421 gataagctaa agattagcaa agaattaaat gagcaactga ataagctcta tcaaataaca
    15481 agtgaagctc ttatggaaaa acacgagcag atccagcaag aattacaagt acaaattcca
    15541 aaatggaaaa aagagtatga aattcaacaa caagaattga aagaacaaga agaaaaacaa
    15601 cggcaaaaag aaaaagagcg cgaacaatta gaactaaaaa aacgtgaaca ggatcttgcg
    15661 gaacaacaaa tggcaataga aaaacaacgg ttaaaccaag aaaaggaaaa agaagcagct
    15721 gctcgtaagg aacgtcaaga acaaatggat acattacgac aagctcagtt aaattatcta
    15781 gcacaacctc aaccaacgcc ttcagtagct gctgttcaaa ccccaatgaa caaccaaaca
    15841 aatctaactc cttcaccaca gcgttccttt aacggatgga tggtgggatg tattgcaagt
    15901 ttaagcttgc ttctaggtgg agggacagta tttgctttta atcatatcaa tcaatcttca
    15961 caggctgatt ctgtagccac aacggcgtca atcaaggaag aagcccaaga acaagcaaga
    16021 aaagagtatg aacaacaatt ggaagaatta ttgaatcgta ccaatcaggc aacaacagag
    16081 tcaagtatgg aaaatagcaa agagagtgat cctagtaagg ctaaagaagg atcaagcgat
    16141 tcaactgtac aatcaaacac ttccgaaagt tcagaatcaa atgaggtgaa ataatgcgtg
    16201 ttagagaaac aacgagacga aaagacaaac gattcaattt agaaaagaat aggtatcttt
    16261 ctcatttcta tcgctatact ccttcaggag aagagctacc agaaaaacat gacaaacgta
    16321 tttctcaaaa gattttttat agtggcttag cttatcttcc tttaaactat gttgttacaa
    16381 gaataccaga agcatttcat cgatttgaga ttattccagg aagtttacaa ggagtgaata
    16441 tttttcagtt acaagaaatg ccgcagttat tccattttga ttcaactggt ttttggaatc
    16501 ctttgacccc aacaacaagt ttaggcacac gtttagttgt ttctacgatt tgtgttgttc
    16561 cagctatact tatgggattg aaaatggaca tgtggtttcg tcctctagca gatgggcaaa
    16621 aaggagataa ccgattaaaa acgttaaagg aaatccaaca aatttatccg caaataccag
    16681 aatcaaaggg aggttttcct ggttatggcg gaataccaat tactcattat aaaaagtact
    16741 ggtatattca gacggataca gtaaatactt gtattgttgg tacttcccgt tcagggaaag
    16801 gacagataga agttttagca accattgaca atttgtctcg tgcagaaaga caaagttcaa
    16861 tggttgttaa tgatccaaaa acagaattat atgttgctag taaagatgaa ctagaagcta
    16921 gagggtatga tgtgtatgca tttaatatca ccgatccact gcaatcaatg agtgataatc
    16981 cattggcact catcgtgaaa tactggaagc gaggagacat agatactgca acgcagttaa
    17041 ccaatacttt tacgaatacg atttattatg atgccaatgc ttcagacaac aaatacttta
    17101 acgaaaatgc gcagaaagct gtaaatgcgc ttatttttgc gttgttagaa caagccgatc
    17161 aaacagggga ttactccaaa ttaacaccca ataatcttgt tgagcttctt tctgaaattg
    17221 gcggttttaa ttatcaagat cctgagaatg attacagaca actcaatgcc ttagatgaat
    17281 tcatgaatca gttaccacct ggaaacatag caaaaaaaca atatggggca acaaaaattg
    17341 gttctgataa agcaaaaggg aatattttat cgacggcaat cacaggattg aatccattta
    17401 ccctaacgaa aattgcgaaa atgacttctc aatcaaccat tgattataag tccattggtt
    17461 ttccgaagta tttggatctc aaactacacg agagtctgtt aaatcagcga attgttgtag
    17521 agttttatca tcaagggaaa aaatttcatg aggaacgtgt caaagtaggt tatagaggtt
    17581 tttgtgaaat caactttgat tgtcatttag agcagggaga tcatgtttgc ttaaaatacg
    17641 atcatcaagg aaaagaatat gttgcttggt atgagttttc tcaaagagta ttgaaagacg
    17701 aagagggaaa tatcgtttat cgaaaaaaac gaggagaaac ccatttacca gaattagaaa
    17761 aagaagctgt tctaacatta gatgaggata aaagtaactt attagtagag tctattcgga
    17821 tgcactatac cgataaacca atggctattt ttatgctcac acctgattat gatccatcta
    17881 accatatcat tgttagtatt tttcttagtc agttgtataa agaattatct acgcaatgtg
    17941 ttaagactaa aggagataaa tgtcaccgta ggattcattt tattttagat gaatttggga
    18001 atatgccacc aatggataat atggaaggaa tcatgacagt cacagctggt agaaacatgt
    18061 tgtgggatct gtttattcaa tcctatcagc aactttatgc gaagtatggg gaacaaaacg
    18121 cagcgattat caaagaaaat tgtcagacac atatttatat tatgtcgaca gacgataata
    18181 ccatcgaaga attttccaaa aaagtgggga ataagacggt tgaacaagag aacagtacca
    18241 ccaattcatt aggtatgaat actcatatca atcgcaatgt tgattcagat cgtatcttaa
    18301 ctcctgaaag aatttctact tttttagaag gtgaaacgat tgtactcgct cctttaaaac
    18361 gacaagattt gaaaggtcat aaaatacggc cgtatcctat ttttaatcat ggggaaacga
    18421 atcttcctta tgcttatcaa tatattgaag atttcaatcc atcgtgggat atcaatgata
    18481 tagacataca ttgtacacat gcggacttgg atcttaaggc tttacaaatt gattacgatt
    18541 attttctacc tgatatctat gcacgtcgac tttatcacaa tatgcacgat caaatagaag
    18601 aggaagctaa agaaaacatt tttattaaaa tcgttcaatc tttagacaac tcaacggcac
    18661 aaaagttact tattcaattt tatgaagaga agcaaataga tcgtttgcaa gaataccttg
    18721 aaaaattgca tcaaaatgaa gaaattacag aggttataag gaaacgactt ttgctagaag
    18781 ctgaaaaggc ggtgaaagaa tgatcattgg aggaatattt tccggcattg ccaactggtg
    18841 gtcaggctta tttggggatg gggatgcaga tcccaaaacc gtaacgaaag tcttacaaga
    18901 ttatggtaat tatctgcagt atcaagatgt attcagttgg atttgtaata cttttttatg
    18961 gggtttgatt aaagggttat ataatctcaa tactttacta gaaaaaacaa tttatcaaag
    19021 ctttgattta aaagacttat tgaacgctgc tggtgttaat gaactgtttc aaagtttgat
    19081 tagtaaggta ttggctcttt tttgtgtcgt cacattaatt tatttaggct taaaattttt
    19141 tatgagtaaa catccaccaa aaatcaaaaa tatcttggtt aatctattta tggccatgat
    19201 tttgattttt ggtggtagtt ctttaatcga tgaagggcta aatattagta aaaactttta
    19261 cggagacgtg actgcagcaa ataaagcaga taaaactgga tcacctgctt ttcaaattat
    19321 tcaaaataat gtgatcgatg tgagtacgct actagaaact gatccgaata aagtagaatc
    19381 cctaccaaca gataaaagaa atgctctcac ggcgaaaaac tttaagacag caaatattaa
    19441 ttcagtgatt attcctaagg aagccgctaa gatggcggat gaagataaga gcggtctatc
    19501 agatatacaa aaggatcggc taagagcgtt acaataccga ctggaactgg atgataatgg
    19561 aaaagaaatc cctgtagaga ttagtgatga ggggttagca aaatatgtgt atacttcagg
    19621 ctatcgccga tacattagta gtccagggat tattttagct ggtgaatctt ctttgtcggt
    19681 tgcctattta tttatcttgt ttacgattgt aacttgcatt attgagctgg tatttaaaaa
    19741 attctattta gtaattgccg cgtcaacgga ctttgagaca ggacaacgga tgaaaagtgc
    19801 tatagaagat atttctcaat ccttcttgtt attggcgttt acgattttag aattacgaat
    19861 ctatacatta atgctgtcag gtatcggtga tttgcacgca gcaggcaaga tcaacggatt
    19921 tttgtatgtt gtcgctttaa ttgtactaac cattgcgcta ttcaaaggct ctcaatctgt
    19981 tacgaagatt ttcggtgttg atacaagtct gaaaaacggc agcaattctc ttcttagcat
    20041 gtttgcctta ggaaatattg cgaaaaatgt gggtagtggg gctaaaaacc ttgcaagtgc
    20101 tggtaagagt ggtttaagca atttaaatga tattcgtaaa aatggatttg gcaatcgaaa
    20161 agatgttatt cctgataacg gggaagaaca accagacgat aaagctacaa ttgtacctaa
    20221 tagtaagaaa acagtttccg aaatgttcgg gaaagcgaaa aatggtgttt ctaaagccgc
    20281 agaaggtctt ggttacgtca atgaacgtgg gttaaaagga acagctgaag atcttacaga
    20341 aaaagccaaa gacaccttag aagagaaatt agacggcacg agagctaaag aattggctga
    20401 agctgtgaag aatccatccg aagcactaga aaaacaaaaa gaaaaagctt cagaagtcaa
    20461 agaaggacta aaagatgcgt atggtgaagg acaagtcaat gcagcagtga aggcaaatac
    20521 aacaagtgaa aaagaaaatc aagaaggtgc agcgattcct tcagccaaag atcaccaaga
    20581 tgagttacat tctaacgaaa attcgatcgg agaaaaagat tcagaagaag gacaacatgg
    20641 acagttacca aaaaccgatc cagaacaata tcgttataaa tctaacatta attctgaaaa
    20701 tgaaaagcgc atttcagatt taccaaaacg aaatcaagaa gtacaaacgg atgaggattc
    20761 catcgatttg ccaaatgata atggaatcga agttggaact gaaaaatcaa tgaaaattgg
    20821 tttgcctaag acacaaaatt taccaatgaa agatagtcgt ttgaatcaat tcaaggagaa
    20881 tgatcaaagc tttgttcacc aatcaactgc aggtactgtt caaatgaaac caagtcgttt
    20941 gcctgaaaat ggaaatctga caactgtttc ttacaattta tctgaaagtg gtgagacagg
    21001 gaatgtgtcc attcaaaatg ttgtgacaag agaagctgca ccagaaccta ttcaaaaagt
    21061 tcacacaggt tacaaaccag caaatgtggc atttactgca ccaacaaaaa taaatgtaac
    21121 aagagaaact aaaaacagga acaatgaatt gaaagaacaa ctattgaggg atatcaaaca
    21181 ggatatcaaa ccataaaagg cctacgagtt aggccttttt tctatgtatg aaaaggagaa
    21241 atcatttatg gataaatata ttaacatgaa aaatcctcca agatttagtg gggaatggaa
    21301 gtttttcgcc tttttctttt tagatctatt aacgcttggt ggttgctttt tttgggcgaa
    21361 aatagtcaat aatcttgtcc acttaccact cttttttgca ctcttgaatt atggcttatg
    21421 gattgcgata gctctagtga ttgtttggcg accttataat aacccaggtc aacgacaaat
    21481 ttttgcgatt atcgaatcta ttttctttgc ggataagaac cactatcatg cgttagatcc
    21541 taaccgaaat tatcatggta cgtataagga ggatgaataa atgcgagtca aaggacaaaa
    21601 ttcagttgat aagaaatcca ttttgcagtt tggaaaacca gaagaacgat ctatcttgga
    21661 tttatttcct tataaatcct gtacagaaga gggagtctta gttactaaag aagatcattt
    21721 tcaacgttat tatcgtgtag tttctacaga cgtggaa
//
LOCUS       DACGMI010000050        21623 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.051, whole genome shotgun sequence.
ACCESSION   DACGMI010000050 DACGMI010000000
VERSION     DACGMI010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.051"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(587..1612)
                     /locus_tag="IXT46_002107"
     CDS             complement(587..1612)
                     /locus_tag="IXT46_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4948008.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            1887..3572
                     /locus_tag="IXT46_002108"
     CDS             1887..3572
                     /locus_tag="IXT46_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAQ4948009.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            3586..4869
                     /locus_tag="IXT46_002109"
     CDS             3586..4869
                     /locus_tag="IXT46_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAQ4948010.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            4939..5808
                     /locus_tag="IXT46_002110"
     CDS             4939..5808
                     /locus_tag="IXT46_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4948011.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            5805..6641
                     /locus_tag="IXT46_002111"
     CDS             5805..6641
                     /locus_tag="IXT46_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4948012.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            6667..7734
                     /locus_tag="IXT46_002112"
     CDS             6667..7734
                     /locus_tag="IXT46_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAQ4948013.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            7731..8558
                     /locus_tag="IXT46_002113"
     CDS             7731..8558
                     /locus_tag="IXT46_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4948014.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            8603..9628
                     /locus_tag="IXT46_002114"
     CDS             8603..9628
                     /locus_tag="IXT46_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4948015.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            9625..11808
                     /locus_tag="IXT46_002115"
     CDS             9625..11808
                     /locus_tag="IXT46_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAQ4948016.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            11808..12938
                     /locus_tag="IXT46_002116"
     CDS             11808..12938
                     /locus_tag="IXT46_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAQ4948017.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            12935..13612
                     /gene="pgmB"
                     /locus_tag="IXT46_002117"
     CDS             12935..13612
                     /gene="pgmB"
                     /locus_tag="IXT46_002117"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAQ4948018.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            13696..14223
                     /gene="msrA"
                     /locus_tag="IXT46_002118"
     CDS             13696..14223
                     /gene="msrA"
                     /locus_tag="IXT46_002118"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4948019.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(14424..15110)
                     /locus_tag="IXT46_002119"
     CDS             complement(14424..15110)
                     /locus_tag="IXT46_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAQ4948020.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            15190..16728
                     /locus_tag="IXT46_002120"
     CDS             15190..16728
                     /locus_tag="IXT46_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAQ4948021.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            16848..17315
                     /locus_tag="IXT46_002121"
     CDS             16848..17315
                     /locus_tag="IXT46_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAQ4948022.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            17834..18277
                     /gene="rplM"
                     /locus_tag="IXT46_002122"
     CDS             17834..18277
                     /gene="rplM"
                     /locus_tag="IXT46_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAQ4948023.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            18293..18685
                     /gene="rpsI"
                     /locus_tag="IXT46_002123"
     CDS             18293..18685
                     /gene="rpsI"
                     /locus_tag="IXT46_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAQ4948024.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(18774..20000)
                     /locus_tag="IXT46_002124"
     CDS             complement(18774..20000)
                     /locus_tag="IXT46_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4948025.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISSALTHSDISTTRIYVNTPDVV
                     DKTVFEAFQRGLNKCD"
     gene            complement(20072..20230)
                     /locus_tag="IXT46_002125"
     CDS             complement(20072..20230)
                     /locus_tag="IXT46_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4948026.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            20918..>21623
                     /locus_tag="IXT46_002126"
     CDS             20918..>21623
                     /locus_tag="IXT46_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAQ4948027.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFI"
BASE COUNT         7015 a         3828 c         4499 g         6281 t
ORIGIN      
        1 aaaaagaggt tgtgacaaat tattgtcaca acctcttttt tggtttgtct aaaataattt
       61 gtctaactag aagaaaagtg ggaaaggatc ttaacaacat cggttcgtat ccaattaagg
      121 tatcggaacg atcatcttcc aagagaagtc aatcaacaaa agtaaagata gatcattttt
      181 tgaatgcaaa ataaattgat gggaagatag agcggttatt tttaatattt tgctagctat
      241 tattgaataa ttcctcgaat aaaacaaaac cagtagacat gtctgttatt ctatttatgt
      301 tttagagata agtatcccca aataacatgg attgaaataa gggtaaatgt gtttaaaaaa
      361 acgaactata aaaacttata cacaacgtgg ttaaaaatag ttttttcttc cctgtggaaa
      421 aaatagttta acacaaacat tatagttatc cacagctatc taaaacagat ggaaaataag
      481 aaaaattcgc taaaataccg ggagggggta acgagggatg agtgattgaa aaaagaacag
      541 agtaactgac ttatcctcag tgtttctgtt cttttataat tctgttctac atttcttgtt
      601 gttggatcga atctgtgaga gtaatctcgg ttgaaagaat gattcttttt tcttcagggt
      661 attggtggtg gattagttgg aataaaagtt ctgtggcttt gattcctaac tgatttgtcg
      721 gaatgtctat ccgagtcaac tgtggcgaaa atagggagga caataaggga tcactgaatc
      781 ctgcgatcga aagatcatca ggtatctgct ttccagattg ttctgccact ttgtaaatac
      841 tcaatgattt taatgcatcg gtagaaaaaa tcgcagttgg tctttctcgt agcttcatta
      901 aatcattcat tgctgccatg ctatcttcta agcgaaagcc gccgtctata atccattcat
      961 tacggatatc taggtggtga tcaaataagc attgacggta accattgaga cgatcattgg
     1021 atacataaac ttctgtcgga gcatggagac agccgatatg acggtgtcca ttcttgatca
     1081 gtgtttccac caaatcgtaa ctatcctgga aattatccgt gtccactgag tagatgttcg
     1141 tgtagtcgtt tccgactttt ccgattacca caataggaat attgtattga tccaattcaa
     1201 aaagaagtgt ttcatccatc gtagagctta aaataataat tcctcggatc attttttctt
     1261 ggatcttttt cgcgcatttt tctagctctt cttctggtgt ttttgccgtt tgtagaatca
     1321 agtcgaagtt attttgttca gaaacggcag aaatggattg aataacatct gaaaaaaaag
     1381 gattgccata ggtcgtatga gaagtacgat gagataatgc tagaatcgcg tcaaaaccat
     1441 ttcctgacag tcctcttgca attttgctcg gttcataatt caattctttg attgcttgaa
     1501 gtacacttgc ttttgcttta tcagagatat ttggctggtt atttaatact ctggagacag
     1561 ttgattttga gacattagct tttttcgcaa tgtcataaat agtaggtttc aattttatat
     1621 gcacctcctt tttgggagcg ttttagaata attccatagt acaatagaca ttcttttttg
     1681 tctatgattt tgaaaattta ggaatagctt gcatgatcat gagagaccat atttttttaa
     1741 gaagctatta attattgata cataagcttt cttatttgta tttttgtgta tatcaaaatt
     1801 atttaaaaaa atgctattga cagtaagcgt tttccataat atgatcaaat cgttgggaac
     1861 gctcccaaaa aagaaagggg aatccgatgt atacaaaact tttacaagcg atttatcgcg
     1921 actcagattt gtctgagaaa accgcctcta tgattgaaca aaaagtcagt gtttatcagc
     1981 agaagaaagg ccaggcaggc aaactgcatt gggacgaaga agatattttc ttgattactt
     2041 atggggatca attttttgaa gagcagcaac caactttgcg tacatttaag aaattttatc
     2101 aaaagtattt ggcagataca tttagagttg tacatttctt gccatttttc ccatatacat
     2161 ctgatgatgg tttctccgtt gtaaattatc aggcaatcaa cgaccgtttg ggcacatggg
     2221 aagatataga agaaatgaga agcgaaacac ggttaatgtt cgactttgtc tgcaatcata
     2281 tgtctgccga aagtacttgg tttcaggaat atttaaactt gaatgatacg tacaaagatt
     2341 tttttattga tttgccactg gatacagata caagcagcgt gactagacca aggaccagcc
     2401 cgttacttac aacgttcatt gacaaaaacg ggaaagaaaa acacgtatgg acgactttta
     2461 gcgaagatca agtagacttg aattttaaaa atccagaagt tttattgaaa atgatcgata
     2521 ttcttttgtt ttacttagaa aaaggcgctt catttattcg cttggacgct gtgggatttt
     2581 tatggaaaga actaggaact tcttgtatac acctgccaga aacgcataaa atcatccaat
     2641 tattccgtgc aatcgctgat gaagcagctc caggaacggt attgatcact gagacaaatg
     2701 tgccacacaa agataatatc agttattttg ggaatggcga gaatgaagca cagatggtct
     2761 atcagttttc gctaccacct ttgacccttc aagcgattcg ttcgggtaat acaagtaagt
     2821 tgaaagaatg gttaaaaacc atcgatttcg catcgaaaaa aacaactttt tttaattttt
     2881 tagcctccca tgacggtatc ggattgaatc cggtacgagg tattctgccg gaaaaaacga
     2941 tccttgaatt agtggaacag ctgaagaaag agggtgcccg agtaaactac aagaaaaacc
     3001 cagatggaac gaccagtcca tatgagataa acgctacgta tctagatgcg ttaagttctc
     3061 caacagatac gacggaatgg agaagcaaac gctttttagc tgctcattca tttttggtaa
     3121 cgttaccagg cgtgccggca atttatattc aaagtgtgct gggaagtcga aatgattaca
     3181 aaggcgtaga aaaaacagga gagaatcgaa aaatcaatcg gcaaaaattt ttgttagcag
     3241 atattgagaa agagttgcag acagatccat taagaacagc agtatatggt gaattgaccc
     3301 agatgctatc tattcgaaaa aaagaaaaag ccttccatcc gaatagtttg atttacttac
     3361 tggactcagc agattctttt atcagtttta ttcgcgaagc gaaggaagag aaagtcttag
     3421 ttatccataa tttttccaat caatcagcag gttatctttt accaaaagga gattacctag
     3481 acctgttttc tggacaaatt atccattgca gtcaagaacg aaagttgata ttccagccgt
     3541 atgaatatat gtggctgaaa ataataaaat aagaggtgga aaaaaatgaa aaaaattatt
     3601 gttactacct gtctgctagc tactggattt cttcttactg cttgtggtga aagtcaaagc
     3661 tctaacgaat cacaacagac aacgattcaa ttcatgcact cttctgtcga acaggaacga
     3721 ttaagtgtga tcaatgaact ggttgctgat tttgaaaaag aaaatccaga catcaaaatc
     3781 aagcaagtgc cggtagaaga atcagcgttc aatacaaaaa tcgttacgtt agctcgttcc
     3841 ggtaaattac cagaagtaat ggaagtcagt caggattttg ctaaagtgat ggataaagat
     3901 gaactgattg atcagacggc agtccaaaac gttatcgagg aagctggaga agataattat
     3961 tatgacggag ccaaaaacct tgttcgttca gaagatggaa aaagctatat tgctgcacca
     4021 attagcggct gggttcaagg tatttggtat gacaaagaaa aattatcaga agctggtttt
     4081 tcagaaccag aaaattggga tgatatttta aaaattgctc aacatttcac agataaagag
     4141 aataaacaat atggaattgc tatgcctact gctgaaggaa caatgagtga gcaagcgttc
     4201 tctcaatttg ctttgtcaaa tggagcaaat gttttggatg atgaaggcga ggtaacgatc
     4261 gatacggaaa agatgagaga agcattgtcg ttttatcaaa acttatccca atacacgatg
     4321 ccaggctcta atgatgtgac agaaatcaaa gatgctttca tgaatggaac agcaccaatg
     4381 gcaatctatt caacttacat tttgccttct gtttatgaag cggggaactc agaaaatatc
     4441 ggttttgcta tcccaacaca aaaagatcaa gctgtctatg gcacagtatc tggattgacg
     4501 atttcttctg gtctagacga gaaacaaaaa gaggctgctg aagcattcac agctttctta
     4561 tctcaaccga aaaacatgga aaagtgggtc ttgatgtctc ctggtggtgc tcaaccagtg
     4621 aataaacaag tagtcgaact ggatggttac aaagaaaatg aagtcatcaa gtcttttggc
     4681 gagctgccat ctgagattgc tagtgctttt gatgaagtac aagtctttgg actagtcggg
     4741 gaaaagaatt tcacgaaaat gggagatatc acaagctcag gtgtgatcgg aaaagcagtg
     4801 aaccaagtaa ctgtcggaaa cgaagatgtc gatcaagctt tagctgacgc acaaaaaaat
     4861 acgaaataac aagaagttct gccaatggtg ttcgaaaaaa gtagatagct attggcagat
     4921 tatcaggggg aggtttcaat gaatcgtcca aggaaacatt ctgacttaaa attagccatg
     4981 ggacttttag caccaagcat gcttttatta gctgttttag tgctgattcc aatgctttcc
     5041 aatattcaga tcagtttttt cgatatgccg ctgaatccta actcagacgc cgtttttatc
     5101 ggattaagca attatcttga aattttaagt gatagtgaat tttatcgttc tttaggttta
     5161 acagttgctt acacattctt agttgtagca ggcagtacag ctttaggatt agccgtagct
     5221 attttgctta accgcaagtt cagatttagg aaaacggtgc gttcactgat tttattaagt
     5281 tatgttacgc catctatttc tttgattttt gcttggaaat atatgttcaa taatagttat
     5341 ggaatcgtca atgatctgtt agtagatagg ttgcagcttt tcaacgaagc accgctgtgg
     5401 ttcgaccagc cagttgctag cttctttatg gtcgttttgt ttgctatctg gagatactat
     5461 ccgtatgcgt ttatttcatt tttggctatt ttgcaaacag tcgacaaaac gctttatgaa
     5521 gcagctgaaa tggacggtgc aaatgcttgg cagaagttca agatcgtgac actgccggca
     5581 atcaaaccag tactagcaac tgtgattgtt ttacgatcta tctggatgtt ctatatgttt
     5641 acagatgtct atctactgac gaataaagtc aatatcttag gcgtttattt gtatcagaca
     5701 gcctttgcgt tcaatgatct tggaaaagca gcagctatat cgattctatt gttcatcatt
     5761 attgcagcgg tcgtcttgct ctcacgaaag aaggtggact tgaaatgaaa aataaaaaga
     5821 gcaggaaaat cttattttac gcgacgattt tgttgctatt agctgtcaat ttgtttccat
     5881 ttttgatcat gctgatgaca tcattcaagg attcacaaga agcaattgca acgacacaaa
     5941 ctatttttcc gaaagaatgg acttttgaac attatcagga tattttcaat gctgagattt
     6001 ttccattcat catgtatttc aaaaatagtt tagtgatctc cttgatagcc tccgtaactg
     6061 cagtagtgat tgggatcagc ggggcatacg ctttgtcaaa actacgcttc aaagctcgct
     6121 cgaaaatcaa tgctagcttt tacaccgttt atatgttttc cggtattttg atcgttgttc
     6181 cattatttaa aatcatttcc ggtctaggtt tgtatgatac caatacagca ctgattatca
     6241 cgatggtcgt tcaaacactt cctactgcga tattcatgct aaaaagttat tttgacacga
     6301 ttccgactga tattgaagaa gcagcaatga tcgatggtct tagccggatc cagatcatta
     6361 ttcggatcat tataccattg gctatttctg gaatcatttc tgtcttcgtt tattgcttta
     6421 tggtttcgtg gaatgattat ttatttgctt cgattttcct gtcgacctcc gaaaaattta
     6481 ctttaccaat cggtttgaac acattattca gtacaccaga ctacatttgg ggacgaatga
     6541 tggccgcttc attggtgacc gctttaccag tcatcattat gtatgcgtta tctgaacgat
     6601 ttattaaagg tgatttagtc gaaggcggcg taaaaggata aaaagaaaag aaagaggaaa
     6661 gaaaagatga aaaaattagt tgcattagaa ccaagaatag ccggattcaa agattacgaa
     6721 gaccgtgaga tcgaaaagaa cgaagtacgt atccgagtaa ttttcgctac tccaaaacca
     6781 ggaacagaaa ttgtcgactt tagaggatta agtccattta tcgatgaaga attttcagaa
     6841 gaatggcgcc tattcttgcc aagagaagaa ggaagccaac gcggtgtggt atttggcgaa
     6901 tttcaattag gaaatatgat tgtcggtacg atcgaagaaa cgggcagttt ggtgacagag
     6961 tatcaaaaag gagagttagt ctgcacttat ggacccattc gtgaaacgct gattacaaac
     7021 ggtgttgata attataaact acgtaaactt gatcggttgg atcaatggaa aaatgcagta
     7081 tgttacgatc ctgctcaatt cgctttaggt ggtatccggg aagcacatgt tcgagcaggt
     7141 gatgctgtag caatcttcgg tttaggcgct atcgggcaaa ttgcgattca attagctaaa
     7201 aaagcaggtg ctactaccat cgttgggatc gatcccatag cgcagcgtag agaattagca
     7261 gaaaaatacg gtgccgatta cacgctagat cctatgaaag cagatgtcgg ttttcgtcta
     7321 aaggaattga cagataaacg tggagtagat tcagttattg aaacgagtgg cagtgctgcc
     7381 gcattacaag cttctttaag agggatcggc tatggcggga tcatttctta tgttgccttt
     7441 gctaaacctt ttccagctgg gtttaatctt ggtcgcgaag cacatttcaa taatgcaaaa
     7501 atcgtctttg ctcgagcatc tagtgaacca aacccagatt acccaagatg gaaccgtaaa
     7561 cgaatcgagg acacatgttg ggaattattg atgaacggtt acttggattg tgaagaaatc
     7621 attgatccag ttgtgccatt tgcagaaagc gcagaagctt acatgcgtta tgtagaccag
     7681 cacccagaag aaagtatcaa aatgggcgtt caagtccgag gaggagaaca atgaaattcg
     7741 gtacgcaaga tcaagcattt ttcccaagag acattttaga aaaatttaga tttatcaaag
     7801 actgtggatt tgaagaatac gaaatcgacg gtaagttgtt aatagaaaat atcgacacag
     7861 tcaaacaggc aatcaaagaa acagggatcc cagtagtgac agcttgtaac ggctacgatg
     7921 ggtggatcgg tgactttatc gaagaacggc gtcttaatgg tgtacgtcaa attgctgaga
     7981 ttttgcgtgc actaagcgag gttggaggca aaggaatcgt tatcccagca gcttggggaa
     8041 tgttcactta tcgattaccg ccgatggttt caccccgaag caaagaagga gactataaag
     8101 cagtcagcga atcacttcgt tatttagata aagtagccga agaaacaggt acggttattt
     8161 atttggagcc tttgaaccga taccaagacc atatgatcaa tttgttagcg gatgcgcgtc
     8221 attacattga ctctaatcaa ttgaaacatg tgcagatcat cgctgatttt tatcatatga
     8281 atattgaaga agatgatatt tcaaaagcat tgactacgca aaaagagtat gtgggtcata
     8341 tccatttagc agataatcat cgctaccaac caggatctgg cgcaattgat tttactcgcc
     8401 attttcaaac gctacttcaa aatgagtatg aaggttatat ggtatatgaa tgtcgtttgc
     8461 gaggagaaaa tgaagtgaaa atttatcagg aatcattgca atacttgaaa aactgtctgg
     8521 aaacagcgcg tcatttaaat gatttagaga aagaatagag aaagaataac aataagtaaa
     8581 taagcaaagg agggagaaat aaatgaagaa agtagcaatc ataggcgctg gacaagtagc
     8641 agaaaaagta catgctgctt attatcaaaa aagatcagat gtcttagaat tggccgctgt
     8701 ggttgatcca gtcagccagc gagcagaaga cttttgccga cgtacaggat tttctcatgc
     8761 gtatacatca gttacacaaa tgctgaatga gatttctccc gatatcgtga gtgtctgtac
     8821 acccaatcgc tttcacttcg aacatgtatt ggctgccctc gaagctaatg cttcagtgat
     8881 gtgcgagaaa ccaccagcta tgacagctga tcaagcaaga aagatggcag agacagccga
     8941 taaaaacggg cagattttgg cttatggatt ccagcatcgt ttttctgacg aagcaacaat
     9001 gatcaagaat catcttgatg ttctcgggga tatttattac gtagaagcga atgcgcttcg
     9061 tcggtctggt gttccaggct ggggaacgtt tatcgacaaa gaacttcaag gaggcgggcc
     9121 tttgatcgat tatggcattc acatgcttga tacagcgatg tatattactg gatttcctaa
     9181 agtaaaaagc gttcgggcgt acagcttcca aaaaattggt acgaaaaaaa attcagggaa
     9241 attcgggaaa tgggatccaa gcaaattcac agtagaagat gcaatttttg gcacactgga
     9301 attagaaaac ggcaagatca tccaactgaa tacttcgttt gctttgaata tcagagaaga
     9361 caaactgaat gtggcttttt gtggcgatca ggcaggtgct aatctgtatc caggcgaact
     9421 attcgaagat gtagatggaa agctggtttc cttacaaaag accacgccag ttaatgaccc
     9481 acatgaacta agtatggctc attttgtgaa tcgggcgctc ggtgaccaga ctcagatgat
     9541 tgcagatggc tggcaaggat atgtcatcca gaatctggtg gaaaatttat atcgttcggc
     9601 agaaacagga gaagttatta ccttatgaaa gtagaagaaa aacagtttga tttagagtat
     9661 atcaataagt atgcgagtca gatgaccatt ggaaatggat tttttggtat cagaggaagc
     9721 caggaggaag actatcggaa tcaagtaagg ggaatgtttg cagctggtgt atataaccga
     9781 cctttaggag cagaatcagc cgagttagtg aatctcccag atgtcatcag atgggaaata
     9841 aaaatcgacg gtgaacattt ttctcttgag acgatgaaag ttcttgcata cgagcgggca
     9901 ctagatttag aaatgggaga gcttaaacgc tatgcgctca ttgaaactgc tcaaggaaaa
     9961 aaagtggaag tcattacttg tcgtgttgct gatcaaaata atctccatca ggcagccctg
    10021 aaagtggtca tcaagccgtt gaccgaagac tgccaagtag atgtgaaaac gggtatcgat
    10081 ggacagcaaa ccaattttgg tacacagcag ttggttgaaa aagaactgcg agtatttggt
    10141 gacgatttga tcagtgcatc ctaccagaca acagaaagta aaattgatat tgggattgca
    10201 gctaaattca ataaagcagg tgtattccaa gcaaaaaatc gccggatcac cgcttccttt
    10261 tcagaaaaga tcagaaaaaa tacgtccttt acgctggaga agatcatcgt gctctctacc
    10321 tctcttcagc aaacagaccc gtttaagaaa agtattgccc aagcccagaa aagcgttagt
    10381 tatacagaaa ttttagagca gtcgatgtct tattggacag atttttggca tcagcatcgg
    10441 ataacgatcc aaggcgattc ttctttcgat cagttagcga tggacttcgc tgcttaccat
    10501 ttacagatta tgactccccg caatgatcca agtgttagtg taggggcgaa gggactaact
    10561 ggcgaaggtt ataaagggca tgttttctgg gatacggaaa tttttatcct gcctttcttt
    10621 ttatatcagt ttcctgaagt agcaaagaat ttgctgctgt accgttatga tcgattagaa
    10681 ggcgcacggc aaaaagcaag agattatcac tatcaaggtg cacttttccc atgggaaagc
    10741 gcacacactg gtcaggaaga gacacccaaa tttgctgcat tgaatatcaa aaccggaaca
    10801 agacaagaag ttgcttcagc tgccgcagaa catcatatca gtgcagacct tgcttatgcc
    10861 gttcaagagt atgtccaagc aacagaggat caatcgtttt tagaaacaaa gggaaaaacg
    10921 ctcattcatg aaacagcagc tttttggctg agcagagctg taaaagtcga tgatcattta
    10981 gagatacaca gagtcattgg tccagatgaa tacacagaat atatcgacaa taatgcatat
    11041 acgaactatc tggcgcatta taatgtggcc ttagctgtta aatatcaagc tggcgatccg
    11101 ctttttttga aagaatgtca aaatttttta gataagttat atttgccagt gcctaacaaa
    11161 gaacagctga ttccgcaaga tgacacgtat ctcagtaagc cagttattga tttgaccact
    11221 tacaaagaac gtcctggcag ccagtctatt ttacttgatt atgcccgtag cgaagtaaat
    11281 gaactccaag tcagcaagca agcagatctt gtcatgctgt tatacttatt acctgagtat
    11341 ttttctcaac caatcgtttc taagaatttg cattactatg aaaacaaaac aatccacgac
    11401 tcatcgttga gtaaagcgat tcacgccata gaggcttgcc gtatccaaga aatggaatgg
    11461 gcgtatcatt tattccaaga agcgtgcctg attgatttag gaccagatcc gcattcatca
    11521 gatgacggaa ttcatgctgc ttcattagga gcactatggc tagcagttat atttggtttt
    11581 tcaggtatta cagtaacgaa tggaactctt tctatttctc caagacttcc ttcagcatgg
    11641 gaaaaaattt cttttccttt tatttggaaa aatcacaggt tgctatttgt tttgacaaaa
    11701 aaacaaatag taataaaaaa agagacgaaa gaaacattac ctatttttgt caatggagac
    11761 caataccagc tggaaaaaga actgatcttg gaacggaggg gaaaataatg cgtattctga
    11821 ttgcgccaga ttctttcaaa gaaagtctga cagccttaga ggcagcacaa gccattcaat
    11881 caggttttca agaagttttt gttcaggctg aatatgatct gctacctata ggcgatggag
    11941 gagaaggaac ggtttcatca ttagcagaca gtttaaggtt gaagcggcaa acagcagtcg
    12001 ttactaatgc atttggcaaa aacaaagaaa tccagtacgc ttcagacggt caaactgcga
    12061 tttttgaaat ggcagaaatc gtcggattga aagatgtccc actaaaccaa caacagccac
    12121 ttaggttatc cacgcgagga gtaggagaac tgatacgaca attgttgcaa caaggtgttc
    12181 gacacatcat catcggcgtt ggcggaagta gtaccaacga tggcggcatc ggcatggcag
    12241 aaggtctagg ttatgctttt tacgatcaag ataatcaaaa agtagaagca ctgggagaaa
    12301 atctaggtaa aattgctaca gttgataaaa cgaacgtgcc tattgagctg attaaagcca
    12361 aaatcactgt cattactgat gttactaatc ttttatgcgg aaaagaaggc gcttcttttg
    12421 ttttcggacc acaaaaaggc ttgaaagaaa atgaattagc agtggctgac caagccatgc
    12481 atgattttta tatgagattt gcccctcaag taatcgaggc atcgggcagt agtgctggtg
    12541 gtggaatggg tgcaggactg ttagcatttg cttcagggaa aatagtctct ggcatcgact
    12601 acgtattgga tttactggag ttcgataaac gggtacagca agcagacctc gtaatcgtag
    12661 gcgaaggacg tctagatgga caaagtctaa aaggaaaagc gccagttggg attgctagaa
    12721 gagtaccaga gggcgttcct gtgatagcta tttgcggaag tgttggtaaa ggaagcgaaa
    12781 aagcagcaga tgttggcatt tcggccgttt ttccgatcct tcctgcagct gtgcctttac
    12841 aagaagcttt acagcaagcc actgataatc ttcatcgcac agctaaaaac atcgcatctt
    12901 tacttcaagt cgttcatttt caaggaggta atcgatgaaa atcaaagcag cactattcga
    12961 tttagatggc gttcttgtag acacagctcg ttatcattac gaagcgtggc tggttttagc
    13021 taaccagctg tccattccat tcactgagaa agaaaacgag caactgaaag gaatatccag
    13081 aaccgagtca ctagagcgat tgctgtcatt tggaaaaatg gaacagaaat tctcagaaaa
    13141 agagaaatca gcctttgctg agcaaaaaaa caatctatat cttcaagcga ttcaaaaaat
    13201 ggatgaaaca tccgttttgc ctggtgcaat agctgttctt gagtacttga aaaaaacaaa
    13261 catcaagatc ggattgggat cagcaagcaa aaatgcacgc ctcattttag aaaaaacgaa
    13321 tttgacaagt tattttgatg tccttattga cggcacgcaa gtatcaaaag caaaacctga
    13381 tccagaagtt tttctcaaag gagcacagca attgaatgta ccgccaaatg catgcttggt
    13441 cattgaagat tcagaagctg gttgtcaagc agctttggct ggtaacatgc atgtattggg
    13501 aataggtgaa aacataaatc ttccttctgc tgaatatgtg attcctgatt taaccgtttt
    13561 tgatcaagta cgttcgtttt ggcatttatc agaagccgta tcacgtatat aatagtttcc
    13621 gttttttctg tcacaagcaa aacgttatcc tccttttgga aatcaaggta tgatgagaaa
    13681 aaagggggat tttatatgac aaaaaaagca gttttcgcag gcggatgctt ttggtgtatg
    13741 gtcaaaccat ttgaagagca gccagggatc atttctgtga catccggtta tactggcggg
    13801 catgtaccaa atccaactta tgaacaagta acaacaggca caacagggca tacagaagca
    13861 gtagagatcg aatatgatcc agaagttatt tcttatgatc agttggtgga aatctattgg
    13921 cagcaaaccg atccgactga cgcattagga cagttcgctg atcgcggtga ttcttatcgt
    13981 ccagtgatct actataatga tgaagaagaa cgaaatattg cagagcgttc aaaacaagca
    14041 ttgcaagaca gcgggcgatt cgataagcca atcgtgacaa aaatcgaacc aagaagcgaa
    14101 ttttatcctg cagaagatta ccatcaggat tattacaaga aaaacaagct ccattacaat
    14161 ctttatcgag aaggttctgg acgtgcaggt ttccttcgtc gacattgggg cgtcaagaaa
    14221 taagaagccg aaaaagctac ttatggaaca ccgtatatca gaggttgtaa aaccagcatt
    14281 ttgagctaat actgagggtc agctgattga acaccattta gtggagaggt tgtgaacctg
    14341 tcgcctagct ccaagtcaca aggatttggt aagagaacac tatatatcag aggttgtgac
    14401 aagtcgtttg tcacaacctt ttttcaatac ctaagatgaa ggacaatcag caacgcactg
    14461 ctcaaaaaag gaatgaaagg cagcttttcc aacttttttt tatgacagat aaagtaaaca
    14521 gaaaaaacgg atattccaaa cagactagca agaaacaaga tctgaagcaa ctcttctaga
    14581 gacaagccac cactccaaga aagcatcaac agagtatcgc cagctccgag ataggattga
    14641 ccatagcgaa ggcacacacc gcctacgata aacgttaaca gcacactttg ccattggaag
    14701 acgccggcct gcaaccaaaa aatccataaa attgcccaag aacagaatag cgtgtgagaa
    14761 tggaccatga agtaaaataa atccatcaac gaaaatagca aagccgaaag catccatatg
    14821 aacgtcgaaa aatttcttgc ggaagaaaaa gtaaagaacc aggcaaaaag accaccacat
    14881 aaggcttctg ccaacaaata gtagaagggc aaccgacacc tgcaatagcg gcagcgaaat
    14941 cgttggacga tgatcgagag aatcggaatc aattcatacc aagaaagcga acgacagcat
    15001 ttgacacaat gagatctagg ataaataata gagtgaccta acggaatccg ctgggcggtt
    15061 aaacataaaa atgatccgat acagcaacca atgataaaat aaagtaacac gccatctccc
    15121 ccttttcaaa accaagatac gcaagcttaa actaaatttt tgtacataca taaaatttga
    15181 ggtgaaaaaa tgaacgtttc aatcggatta gatatcggaa ccacacaaac caaagcagtt
    15241 gctttcacag atgaagccca agaagcagca tccgcttatt ttcgctaccc tttgatccaa
    15301 gaaacacaag ggatggcaga acaagatcag gaattgatct ttcaaggtgt ctgcaccgtt
    15361 ataaaagaag taattaaaca gttgccttca gacacaatca ttcaatttgt ctccttctcc
    15421 tctgcgatgc atggcctgat attgttggat gaagagaaaa caccgttatc tcgaatgatc
    15481 acttgggcag ataaccgagc agcggacgaa gcagaaaaac tgaaatatac cgtgcttggc
    15541 aaagaatttt atcggcagac tgggacgccg attcatccaa tgacaccatt gaacaaaatc
    15601 aagtggctgc aaaacagcca acctgaatta ttcaaaaaaa ctgcttattt tgtcggtatc
    15661 aaagactata tcttttatag attgtttggc gaactgatca gcgactacgg aacagcttca
    15721 ggaactggat attttgatat ccatgaattc caatgggcag aagaagtgct tgactacttg
    15781 aacattcgaa tagagcaatt gccgcaagtc tttccttcca cctatcaagt aacaggtcta
    15841 ccatcaaaaa cagcagcaga actaggtttg ccaaatgata tatcatttgt tttgggaggg
    15901 gcagacgggc cgctttctaa tctagggtta ggtgcttttg gtgatacgat cgccgctttg
    15961 accgtaggaa cgagcggagc acttcgtttt attactactc agcctcagtt ccatccagaa
    16021 atggagacgt tttgttatgt tctggatcag aaacattggg tagtgggagg agcgactagc
    16081 aatggtgctg gcatctttga ttgggcaggg catacatttt tacaggaagt cgttcaatct
    16141 gctaaagaaa aaggagaaaa tccatatgat gcactgcttt cggctatcgc ttttgtgcca
    16201 gcgggtgcca atggtctgat ttttcatccc tatttacttg gtgagcgagc accgctttgg
    16261 gacgcagatg cgtttggcag ttttatcggt ttacagcggc aacatacaga aaaagaaatg
    16321 atgaaggcga ttctagaagg gatctgtctc aacctttatc ggattttaaa aggagtttgc
    16381 caggaaaatc agctcacaga gatccgtgct acaggcgggt ttgctcaatc tccgattttt
    16441 cgtcagatga tggctgatgt actgggttac ccgcttgttt tccctactgt cacagaagca
    16501 tccgcattag gagctgtgat tttaggctgg agaagcatcg gaaagatcca aagtatcagt
    16561 gaagcacagg aattgataga attgaaagag caagttggag tacaagaaac tgatcataaa
    16621 aaatatcaga aaatctatcc attatttgtt tcgacacaaa agcatttagc acagacttat
    16681 cagcaatttg ctcaactgcg agaagaatta gctgattctg aaaaatgatt ggctttacgg
    16741 ataaaaaagc gaactgaaaa tcgttctcag gtaaatgatt ttgttgtact tttcattgaa
    16801 agtctactat tattttaagt gtaagaaaat gttaggaggc aagaaagatg aaattccaac
    16861 aaaccaaaga agtattaaat caattagttg cagatctaag ccaaatgtct gttgttgttc
    16921 accaaacaca ttggtacatg agaggaccag gtttccttac attgcaccca atgatggatg
    16981 agttcatgga tgatttgaac gctcagttag atgaagtatc cgaacgcttg atcacattag
    17041 acggttcacc ttattctaca ttgcgtgaat ttgcagataa cacaaaaatc cctgatgaaa
    17101 ttggccgctg ggatcgtact attccagaac gtttggaaac acttgttgca ggctatcgtt
    17161 atctagcaga tctttaccaa aaaggaatcg aagtttctgg agaagaaggc gacgatccaa
    17221 cacaagatat ctttatcgaa ttcaaaacag ccacagaaaa acgtatctgg atgatccaag
    17281 ctcatttggg caaagcgcca gagatcgacg cgtaaaaact gttgttgaac ttgaccgaaa
    17341 aagaggttgt gaaatcagcg ttttgacctg agtattagag aaacaaacgt caaaatagtt
    17401 cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa caccgtttac
    17461 caagaggttg taagcctgcc gttcagctcc gagtcacaag aaacaatttt aaaaaacagc
    17521 ttcttatgtt ttatggatat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
    17581 attcaaaata aggggttgtg acaagacttt tgtcacagcc tctttttgtt tttcattttg
    17641 acaggaaacg acccttttat ataaaagaaa gaaaagaagt aaagtttcat ataaattttt
    17701 caatcaagca gaaaaacgtt gacattgact agattagcgg gtaatatgtt aaatggtatt
    17761 gtttgcccca caaagagccc cggaaactcg aagtgtatgt caaacatcag aacttaaatt
    17821 ggaggaaaat aacgtgcgta caacatatat ggccaaacca ggcgaagtag aacgtaaatg
    17881 gtatgtagta gacgcaactg atgttccatt gggacgtctt tcaacagttg ttgcatctgt
    17941 actacgtggt aaaaataaac caactttcac acctcatttg gatactggcg atttcgtcat
    18001 cgtcatcaat gcagacaaag tgaaattaac aggtaaaaaa gcgactgaca aaatttatta
    18061 ccgtcacagc aactacccag gaggattgaa atcaatcact gctggcgaat tgcgtgctaa
    18121 aaattctcgt cgtttgatcg aaacttctgt aaaaggtatg cttcctaaaa acactttagg
    18181 ccgcaaacaa tttacaaaat tgaacgtata cggtggagca gaacatccac atgcagcaca
    18241 acaaccagaa gttttagaca tcacaaactt aatctaatag gagggaattt cattggcaca
    18301 agttcaatat atcggcacag gccgtcgtaa aaacgcagtt gctcgcgtac gtctagtacc
    18361 aggaactggc aaaattactg taaataaaaa agatgttgaa gaatacattc cacatgctga
    18421 cttgcgtgaa gtaatcaatc aacctttcgc tgttactgaa acaaaaggcg catatgacgt
    18481 atttgttaac gtaaacggcg gaggatacgc tggacaatca ggagctatcc gtcatggtat
    18541 cgctcgtgca ttgctagaag ttgatcctga cttccgttta gctcttaaac gtgctggctt
    18601 acttactcgt gacgcacgta tggtcgaacg taaaaaacca ggtctcaaaa aggctcgtaa
    18661 agcatctcaa ttctctaaac gttaatatta tttatatatc aatgtttcaa ggcacttttc
    18721 aattgtttga aaagtgtctt tttcttgttt aagaacacat ttaagaacac atactaatca
    18781 catttattca atcctctctg aaaggcttca aaaacagttt tatctactac atctggtgta
    18841 tttacgtata ttctcgttgt agaaatatct gagtgtgtta aagcactaga tatttgattc
    18901 atatttgctc cgccttgtct agctatagtt gcataggtat gacgaagctt atgtggagat
    18961 aaatgagcca attcaggatg tcgtctttta attgaattga ttcgatagtt taggtaatca
    19021 gcgtgaacag ggcaatttac ttctccggat ggtttagtat aggtaaagag atactgatct
    19081 ggtgtttgat taatttttaa tctcaacaat tgctcagctt gcactgattt ccatttgctt
    19141 agtaatgcca ttacaatttc gggtacttga attacggtat cctttcgacc ttttgtaaat
    19201 ttcttttttt gatatttatc caaagcatgt ttaaggcgaa ccgtttgttt ctcaaagtcg
    19261 atatatttcc attgcaaagc atacgtctca ctttttctat caccaagata tagggtaagc
    19321 atgaaaagag tatagtcatg aagagtaagc aagtgattat tcaagtcagt gtttactgct
    19381 tctatccaag caataagctc ttctgacgat aatgcttgat taccttcccg tatccttctt
    19441 tcttctaaag caattttttt aggtgcagtg atacattgaa taattttggt agttcggtta
    19501 aattcaatat aatttagtat ttctgcaata tcaaacatag aacggacata tcctttgata
    19561 atttttatat ttgcgtattc tttcgatttt tttgttaatt catctgatat tatctcagta
    19621 tttgaattta gatagttcat tgcatactca ccaaacattg gaaggatgtg caatcggaat
    19681 atatctttag tattactaat tgttacgtaa cttggagctc tttttgatct agtagtctga
    19741 cctagttcat atctaggaag ccattttgat tcatagaatt ccttaaattt tatttttcct
    19801 tttaattcta gtgaatttgc attctcctct cttaaaactg tttcaatttt ccttttcatt
    19861 gcattttcgg ctttaatagc caattgccta gttggaaata ctttttgata cttttctgat
    19921 gtaattccag tgatttctct gaattttttt ggatacctca gattagtttt atatttccca
    19981 tttgaaagtt ttgtaggcaa aattcctcac tcccttaaaa agtaaggcag tatatttcgc
    20041 tattcttagt atatgcggcg agaagaaatt ttcaaattgt tttaaatgta ttcataaaat
    20101 ctttgatatc ctctatgtca aagcgaacta taccgtcaat tctgattact ggaaaattat
    20161 atatacgaat ccacttatct aaagtattat tatcaattcc tagaaactca caggtttgtt
    20221 ttttattcaa gtagactctc aattttataa aatcatctcc taaaaaagat tagaattttt
    20281 gaattgcttt gggtaagcac ataggaattt cacctctccc cagtttacgg cgagccttac
    20341 ggaagtatca ttatttgctg ctattgtcat ggcattttgt tttcccagaa caaaaagaaa
    20401 tctctaagta tttgtcgcta atcaggtcat ggcgtacttg agtttctagc tcgaatagca
    20461 gggatcgtta ttcaaaaatt gtatttaatt gtcaatgatc aaaaataggt tttttcctat
    20521 tcactattaa taacgataaa catgtataaa aagacacact acgaaaaaag ttaaatggag
    20581 tttactgatt ttcatatttg tatatggaac agacatagtc ttgaataatt tttataaatg
    20641 ttttgatgct tatcaactta ttcaacccgc tatccacttt aagtataatt tttccatacg
    20701 ccaataaagt agttttagga gcatgttctc atttgagaac gctccttttt tatatatttt
    20761 gaaagctact tactatacgc gtagtttcaa atagttttgt cattctaatc ttcagcaaca
    20821 gaaaaaaatc taaattataa aatttagggt tgactaaaat ataatttttg tataccatat
    20881 gatcgtgata atcattatca tttagaagga gaaagttatg ttagaagtga aaaagcttaa
    20941 tgtttgttat aacgattttt tagcattgaa cgagatttct ttaaaaatac aagaaggtgc
    21001 tttaacaggt attattggtc caaatggtgc tggaaaatct acattgctta aagcaatgtt
    21061 aaatattatc cctcatcagg gagaggtctc cattaataat gaagatatca ataaaaaact
    21121 ggtgaagatt gcatatgtag agcaaaaagc tgatattgat tttacttttc caataaaagt
    21181 aaaagaatgt gtatctatgg gaacatatgc cggaatgaaa gtttttcaaa gaattaaaaa
    21241 tgcagaatgg caaagagttt caaaggcttt ggaaaaggtc gatatgggaa aatattctaa
    21301 tcatcaaata ggagaattat ctggaggaca atttcaacgt gtacttttag caagatgtct
    21361 tgctcaaaat gcggatttca tatttttaga tgaaccattt gtagggatag acttagttag
    21421 tgaacgaata attatggata cgttaaaaga attgaaacat cagggaaaaa cagtgctaat
    21481 tgtgcatcat gatttaagca aggtaaagaa gtattttgat aatattattc ttttgaatcg
    21541 aaatctaatt gctcacggaa gtgtagaatc tgtatttaat gaagagaatt taaaaaaagc
    21601 ctatggagat actatattta ttg
//
LOCUS       DACGMI010000051        21457 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.052, whole genome shotgun sequence.
ACCESSION   DACGMI010000051 DACGMI010000000
VERSION     DACGMI010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.052"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            5..403
                     /locus_tag="IXT46_002127"
     CDS             5..403
                     /locus_tag="IXT46_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAQ4948028.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1082
                     /locus_tag="IXT46_002128"
     CDS             387..1082
                     /locus_tag="IXT46_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAQ4948029.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1676..2563)
                     /locus_tag="IXT46_002129"
     CDS             complement(1676..2563)
                     /locus_tag="IXT46_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAQ4948030.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2748..3587
                     /locus_tag="IXT46_002130"
     CDS             2748..3587
                     /locus_tag="IXT46_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4948031.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3783..4757
                     /gene="sgrA"
                     /locus_tag="IXT46_002131"
     CDS             3783..4757
                     /gene="sgrA"
                     /locus_tag="IXT46_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAQ4948032.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5055..5411
                     /locus_tag="IXT46_002132"
     CDS             5055..5411
                     /locus_tag="IXT46_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948033.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5414..6571
                     /locus_tag="IXT46_002133"
     CDS             5414..6571
                     /locus_tag="IXT46_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948034.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6597..7037)
                     /locus_tag="IXT46_002134"
     CDS             complement(6597..7037)
                     /locus_tag="IXT46_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAQ4948035.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7197..7703
                     /locus_tag="IXT46_002135"
     CDS             7197..7703
                     /locus_tag="IXT46_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4948036.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7871..9784
                     /locus_tag="IXT46_002136"
     CDS             7871..9784
                     /locus_tag="IXT46_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAQ4948037.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9789..10790
                     /locus_tag="IXT46_002137"
     CDS             9789..10790
                     /locus_tag="IXT46_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4948038.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10992..11198)
                     /locus_tag="IXT46_002138"
     CDS             complement(10992..11198)
                     /locus_tag="IXT46_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAQ4948039.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11844..12692)
                     /locus_tag="IXT46_002139"
     CDS             complement(11844..12692)
                     /locus_tag="IXT46_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4948040.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12856..13758
                     /gene="gnd"
                     /locus_tag="IXT46_002140"
     CDS             12856..13758
                     /gene="gnd"
                     /locus_tag="IXT46_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAQ4948041.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            13760..14761
                     /locus_tag="IXT46_002141"
     CDS             13760..14761
                     /locus_tag="IXT46_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAQ4948042.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14758..15042
                     /locus_tag="IXT46_002142"
     CDS             14758..15042
                     /locus_tag="IXT46_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4948043.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15075..15872
                     /locus_tag="IXT46_002143"
     CDS             15075..15872
                     /locus_tag="IXT46_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4948044.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15886..16719
                     /locus_tag="IXT46_002144"
     CDS             15886..16719
                     /locus_tag="IXT46_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4948045.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16737..17594
                     /locus_tag="IXT46_002145"
     CDS             16737..17594
                     /locus_tag="IXT46_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4948046.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17616..18125
                     /locus_tag="IXT46_002146"
     CDS             17616..18125
                     /locus_tag="IXT46_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4948047.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18162..18563
                     /locus_tag="IXT46_002147"
     CDS             18162..18563
                     /locus_tag="IXT46_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948048.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18675..19028
                     /locus_tag="IXT46_002148"
     CDS             18675..19028
                     /locus_tag="IXT46_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948049.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19062..19505
                     /locus_tag="IXT46_002149"
     CDS             19062..19505
                     /locus_tag="IXT46_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4948050.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19522..20607
                     /gene="uxuA"
                     /locus_tag="IXT46_002150"
     CDS             19522..20607
                     /gene="uxuA"
                     /locus_tag="IXT46_002150"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAQ4948051.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20600..21313
                     /locus_tag="IXT46_002151"
     CDS             20600..21313
                     /locus_tag="IXT46_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4948052.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7385 a         3293 c         4477 g         6302 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcatgcgat aacgttaggt aaagagctac
      961 tagatcaagt attagagatg ccctcgattg ataaagcagt gaggggcttc caagaagatt
     1021 gggtgcaaac tttccaagca gaaacgattg gtgaactaaa aaaggtcgct gattacttct
     1081 gaatcaattt ctccataaaa taaacgatag ccttctcgaa aactcgagga ggctatctga
     1141 cgattcaata ttcattaatt taaagtttgg gtgactatta ctaactatta cttatttctc
     1201 atttaaacga tgtattccct aacctctaat acatccttgt aactctgaag ttacgccagt
     1261 tttgaataaa tttcataaaa acaaatgaaa agtgtcgcat aaaaatatct ttcgtgtttc
     1321 tctagtataa cagaataaga agaacaagtc cagaagggat atttttagtc ttttttaaaa
     1381 taacttttca gtcgagtttg agtttatgat agttgttttt gaagcgatac ggcaagtgaa
     1441 aaaataggga agcatgaaag aatctactta atggcgcatt gattcatgtg atagaaataa
     1501 aaaacttttt taaattatat cctcatgatt gtaacaaatc cagtgatttg ttttggtaca
     1561 aataaaaaaa ggccccgatg aagttgtggc aaaagtggtt tgcctcaaaa ataagaagga
     1621 atttccaaaa atcacttctc aaattttgcc acatccccaa ttgggtcaaa tttgtttatt
     1681 tgaatatatt ttttacataa ggatctttaa tagttacatt gtcttttttc atcactttac
     1741 ggattgtttt atccatgaat tccgtatcaa gagtttttgc ttcggtagca attttttcta
     1801 gctcagattt gtatttgtct ttattagaac ctttatcctg tttttttacc atttttacta
     1861 gataatagct ttgctgataa gtcgttggat ctgttacagg aatgatatca gaaacttccc
     1921 cgttttttag tttaaatgct gcttttttta cttcagtagg aatctctgga ttggttgaat
     1981 caaaattcat ttttccatca gtttccttta atgttttatt ttttccataa gcttgaacaa
     2041 gcttggagaa attttctcct tcatttgctt ctttttttgc tttatctgct tcttctttag
     2101 tcgaaaatag aatgatctgt gtactaactt ctggatagaa ttctttccaa gcagtgtcta
     2161 gatctttatc tgttaatttt acattggctt tcaaaccgta ttggaaagcc agcatctgtt
     2221 taaagagttt cttatatgtc tcttctgttt ggccaactgc ttttaattgt tccttgtagt
     2281 ttggaccgag ttttttgatt tgttcattat attcttttgt tacttccttt gaagaaatct
     2341 cttttccgta tacatcatca aatgctttga agacaatcat tttttttaat agtgtttgat
     2401 tatttgattt aacttttggg ttatcataaa aatcctgaac tgtaagtgtt ccacctttaa
     2461 acgttgcaat cgtttcattg gacttgctac aacctgagaa tagtaaaatt gcacatgctg
     2521 aaaggcacat aattagtagt tgttttttca aaaaatttcc catcctttcc ttattaaaaa
     2581 cagtctaaca gaagaattag ggagacagtc tttcattttc gtaaggttgc tgtagatatt
     2641 cttagttcgt aaaaatctat tctctctatg atggagaaca tttacatagt tttcacgaga
     2701 caagaaagaa aagggttgtt aaacttaata taaaggaggg atgaaagatg atcaggatta
     2761 ttcggttgat tggatctgtt ttaatagtct tagttggttt tgttttagga attcttgtca
     2821 ataatgcact tgcggatatg tttattggaa atagtgaatg gattggagca attgccggta
     2881 cggtcggaca tttagctgtt tttttactag ctttatttct tgctagtaag gtcgaaggaa
     2941 aaagaataga agattatggt gtttctgttc gaggaaaaga ctgggggtat ttagcgggag
     3001 gtctcgttgt tggaattgga gtgtttctgc ttattactag tccattatat ttgacggggg
     3061 cgtatcggtt agattcagga aacgcaaaca ttgtgccgct gataacgagt tttattttat
     3121 ttattgcagt gggggcatca gaagagcttt tattccgtgg cttttttcag catcagatgc
     3181 ttagatttgg tccgttaata gcaatgattg gatctgctgc attatttgct cttttgcacg
     3241 gattgaatcc taacatgaca tttctggcag ttttcaatat ctttttagca ggttgctttt
     3301 tcagcgcact tatctacagt acaggaagtt tatttacggc tattggtgct catattactt
     3361 ggaattggac acaaggagct attttgggta taccagtcag cggaacgcaa gaacaaggtt
     3421 ttttctccac tctgatccaa tcgcaaaata caataattac tgggggaaac tttggggctg
     3481 aagcatctat atcaactaca ttattcttgt tagtcttgat tgttggtttg ttactctatg
     3541 catataaaac aaagcggatg aagaaataca ctgctgttta tcaataaaag atgaagaaag
     3601 caaggctgat atcggtcttg cttttttaag tctgtcattg attaaacgaa aaagtaaaca
     3661 aattcaagcg aatacacgac atcttttgtt agattttcac aactgactgt cgtgttctca
     3721 tcattttcat tttatataat tcctttatca aatagaaggt aattatatgg agagtgatag
     3781 aaatgaagaa aacagcgacc gtattatttg ttattcttgg gctgagtata attgcagcaa
     3841 tgattggaat cagtacttct gcaaatgaac gggcaaatga gaatctttca tttactgtga
     3901 aaactgatcg gattgtttat gacatgacac aacaagtcat tactattcca gtcaaaccaa
     3961 acaaaagcgt gaatgctagt gatgtacatg ctgttctaac atatggttgg gatggtaatg
     4021 gaagttcaga aaaagttatt ggggaagttt atttaaaaga cgtacaatgg accgctggta
     4081 ttgagtatac aataatgatt tctgcagaac tatcgattga tgagatcaag agtaaagata
     4141 aagttgattt gattgttttt tatgatggac agatgacgat cacggagaat ttgaaaccaa
     4201 gcagttggac agttgttgga ccgccaagca gtacggatag cacaagtagt gaaagcagta
     4261 cagaaaacac gagcggtgaa agcagtacag agagtacgag cagtgaaagt agcacagaaa
     4321 acacgagcag cgaaagcagt acggagagta cgagtagtga aagtagcaca ggaagcacga
     4381 gcagcgaaag cagtacggag agtacgagta gtgaaagtag cacaggaagc atgagtagtg
     4441 agagtagcac aggaagcacg agcagcgaaa gcagcacagg aaaagtaaat aatgaacttg
     4501 atttggtacc tatcatacca actaaggaac aaaagagaaa tgcagggagc aacctaaaaa
     4561 gtgtgctaaa acagcctgat tttgtttctc gtggaattga tcatcaagaa aaagcgaaag
     4621 aaacagataa tagaaaaagc gatttaccag aaactggtag tagaaccttg aacaagctaa
     4681 ttacatggat gggtgtgtta ctcattttga ttgtaggagc aagctatttt cgttctctct
     4741 tccatcgagt gaaataaaga ataaaagcaa cagatctaaa attgaataaa acgatagatt
     4801 tttgagtgaa tatttcattc gagagtgctg tattgcctgg cgaagttgta gctttgccag
     4861 atctattttt gtttactaac atatttgaga aacaggaaat aacaggaaca caaatggaaa
     4921 ataagagcaa gaataattga caatgcacac tgcgcatggt agtatctctg aaaaatcagt
     4981 aacgaatcta tttgtacgtt attcatgtag ctgtcggaat aagtctaaat aatagataaa
     5041 aaggagtatg tactttgttt gaagaattta ttgatatcaa tgaaaggcaa gtatatcaat
     5101 ttttgaacta ttgttatgaa agagacgaga aattatatgt ggtgaaggat atcgctttag
     5161 atctaaacta caccctggct aagatgaatt cggtgattca acaagcagaa tcgttttgcg
     5221 aaaggtatcc agaatataaa ttatcttttc tttcagaaaa caagatgata aaagtcgagt
     5281 tttcttctca gtttttactg agtaaagttt attctatact tttagaggga acgattggtt
     5341 atattttact ggattcactt tacaaaggta cttatcaatc cttagaaaat cttagtcaaa
     5401 aaattatata agtttgcgta cgattcaaag aaaattaaga gaacttaata ctattttgaa
     5461 aaactatcat ttatcttgca gcttgaaaaa aggtaatccg atagaaggag aagaataccg
     5521 tatccgatac ttttttcact tgatgtattg gcagtcattc gacgaaaatc attctgatat
     5581 attatcaagt ataaaaaata aacgtcaact attagaaaaa tttgcgaaac atgcgccata
     5641 tacgcgtagt atagatagaa agaaatggat cagcctacta agaatttcgt tgcaacgaat
     5701 gaaacaaggc cactcgatta cgtatgtccc agaagagatg aacaaatttg tgcatccatt
     5761 gataacaaaa gaagagttta cgcattacat actagagcct ttttttgaag caaacttctg
     5821 gtcgatgaat cacatcactc caacagagca agcttacctt tattttatgt ttggtgtaat
     5881 gaacacctat ttggaagaag atttgttgga tactccagat aaagtacaag aaagttgggg
     5941 ctggattgaa tcgtctattg tagaaaattt tgaaaaaaac ttcaagattt gttttacaac
     6001 ttcagaaaaa aattatctat atgtcaattt ggcaatgatc catttgtatt caagggtttt
     6061 tgggacaaaa aagaaggtgg atgcttttgg aaaatcagca gaagacagag attttcagca
     6121 tatatttcca gtgatgtatc caatcatgca acagtttttt agtggggtag ctcgcagaat
     6181 tccagagctt aatacttatt atgaaaagaa cagacggttg atttttcaat actgtatgtt
     6241 agtcagggat atttttataa aacacgaaca acctgtcata ttctatattc aatcaaagta
     6301 tggtaaaaca caggaattat gggcaaagaa aaggatatta tctatgactg aacgcccaat
     6361 aaaatatagt gcatccgctg atcagttacc tgatattgtc attagcgatt atcctatcga
     6421 caaaaaggca tatgatcaaa cgaatacaca gatattttac tggaatggac aacctacaaa
     6481 aaatgattgg gcgcgtctga aagctgaaat cataaaaatc aggaatgaga aaaatagatc
     6541 catattggaa aaattggatt tcgttaatta agaaaagcag attgtttatg ccaaaattaa
     6601 gacattgcaa aaagattatt ttctttaaaa tcgacaagat gaccagaaag caagagttcg
     6661 ttgagctctt gctttctttt agttttagaa aggaacatcc tgattttatc ttcgctaaat
     6721 ccagtcaaaa gttttgcaga ttggtcgtag ataatcggtt ttttcaataa agaaggggat
     6781 gtacgaatct caatatatag ttcactcaaa ctgagttcat ctattctgtg aacaagattt
     6841 ttataactaa tagaatgagt agagagcatt tcggtcacgc cgttgtttgt caattttagt
     6901 aagtggataa attcattttt ggttagtggt tgacgaatta agttctgttc gataaacggt
     6961 atatcatgga cgataagcca acgttttgcg cgtcttgaag acgagcagcc agaacctgta
     7021 tacaatttaa tcatcataca ttcctccaat agctaagtat ttatgaaata ataacatgaa
     7081 gaaatagtcg aaaagtgcca tttagaggtg taaaataaga aaatgttgtc acgtataatg
     7141 gaactagcta gataagaaat actattaaat caagaaaaaa gaaagaaggc acaagtatgt
     7201 caaacacagc cgacgcaata gtagtgatcg atttacaaaa aggggtatgt tttgattctt
     7261 cgccgataca cgaattagaa acagtgacag cattagtgaa taaaagaatc aaaacatacg
     7321 aaacgattgg gaaaccagtt attttcgttc aacacgaaga tgctcaatta gtgccacaaa
     7381 caaaaccatg ggagctattg tcggaattat ctattcctga gcacagttat tttgtgagaa
     7441 aaacccatgc gaattcattt tataagacta atttgagtgt tttattaact gaattggact
     7501 gtcattcgat cgaattatgt ggggcacaag cagagtattg tatagatacg actgtgaagt
     7561 ttgctcatgg attaggatac cagcttatga tgtgtagagg agcaacgaca acttatgata
     7621 atccttttat gaaagcaaag gaaacaatcg ctttttacga gaaaatttgg gataaacgat
     7681 ttctgacatt tttggagcaa taagttgttt cttcgtttaa aaaaagcaga atggatactg
     7741 gtttatccat tctgctttat tacgtaaaat gagaaaataa tcctgttcta tttttatggg
     7801 ataaaccatt tattttttgt ataaaaaatg tttgcgttta catataattc tcctagaaac
     7861 ataaaaagga gtgaatagct tgagaacaaa acaagtatta aagggagcgt tggtcatctt
     7921 atttgctgta agtacaagcg tcccgcaatg gacagtatat ggagagagca tttcttccga
     7981 atcggaatct cgggaggtag aaaccacaga aactactgat gctggaaatg aaacgaaatc
     8041 gagtacttca caaacagaaa caaatactga aacaacggtt gagacatctg ttactagcac
     8101 agatcaagaa acgaccgcta ccacagataa ccaacaaaca gaagaagcaa cagctacaaa
     8161 aatgtcaaac gacgaatcct cttctgctaa agtaagtgac aaagagaatg ggacagaaaa
     8221 tgatgatatc ggtaaaggtg aaaatttcaa tggtaaagaa tatttgaatt acttcggtaa
     8281 acagatgaca gaaatactta atggaccaac agaagacatc aagtcaaaat taatagagtt
     8341 attagtcact gagcttgctg ttaatgatta tggtgtagat aaagagatta tcaaacatct
     8401 gattgctact tatctattgt acgatatcgc ttttgcaaaa aacagtgtgt tgatgtcgat
     8461 gcttggaggt acagatgatg ggacaacgcc tacagaaaac acaggcttct atccaaatac
     8521 aaaacaactt catcaaactg tactaaacaa acaagatggc aaaatgatgg atgtatatgc
     8581 atattatgtc gatcaaggtt cagataaaac agtcatgatc catggcggat ttcgagggaa
     8641 ttggaataac gggatcgtta cagaagaata caatgatttt tataaggccg ggtataattt
     8701 attatttgtt gattccagag cgactggtaa tagcggaggc gattatgtga cctatggaca
     8761 atatgagtca gatgacgtcc tttactggat aaatcaagaa gttcgagagc ggccatctca
     8821 aaagatttta ctttatggtg gttcgatggg agcagctacg atgatgtctg tattagcgaa
     8881 agatattcct gtcaatgtca aaggaattat tgaaaattgc ggatttgcat caattgatga
     8941 acaactacgt tttacgtaca gccagacagt agcccccgca ctaccggatg ccataaaaaa
     9001 tcagttagac atcattgggg atcaagagca tgaagattta tttatgggcc ttttgaaaca
     9061 atactatttt gatcaggaga tgcatttgga tacaaaagct gctctaccta cgattggaat
     9121 gtcagattca ttgcctaaat tgattatcca tggaacagca gatgatgtag tacctgtgtc
     9181 taacgcgcaa aaattatatg agttatcagg agggtataaa gatcttttat tagtagaagg
     9241 agcagggcat ggaaaggcac aggaagttga ccatgctgcc tacacgaaac atgtaacgga
     9301 ctttttgaaa gtagtgttcc atgatcagat aaacgtaaag tatgtggatg aaaacaataa
     9361 aagtctactc aaagaccagg acgaaatcca gctttacgga gcttatggag aaaattatat
     9421 gacagagcaa aagacattcg aaggatacga attagcaaat gttgaaggac cgactgaagg
     9481 gatttttaat gagacgatac caactattat tttctattac aaaaaaatcc cagtagctcc
     9541 accaaaaaag caagatccga cagagaatgc agacaataag ggaaagaatg aacctcgaga
     9601 ggatcaatca agtgatgata cgcaaccgat tcagatgaca gtgaaagtac aaaaaaagac
     9661 agatgcaaaa aaaagaatgt tgccgaaaac tggagaaaag aaacattcgc ttctcattta
     9721 ttcaggtgga tttttatctg ttagcacgat tatcacatgg atttggcgaa gaaagagagg
     9781 gtaaatgaat gaaatggttc aagcgaatag tgattgcagt accagttatc atcgtagtta
     9841 ttttagtcac tgtatttttg attaatcaaa tcacaccaaa gccgattagc ttgcttgtta
     9901 gaaaacaatt tgacacaagt gaaaaagaac aagtatatgc ccgaccagat gatttccagc
     9961 aaaaaatcga acaaatcgat ataaaaaaag aaatatccta tccttcaaag tacaaaaata
    10021 ataatatgga tatctacaca ccgaaagtgg aaaagaaaaa attaccgatt cttttctgga
    10081 tgcatggagg cgcatatgta ggaggggata aaaatgattg tcgtgattat ttggaatatc
    10141 tatgttcaga cacgcagcaa atcatcgtaa atatagatta tgaacgatca ccggaagcaa
    10201 aacatcctac accagttatc caattgaacg aagccattca agcagctaaa aaagagataa
    10261 aagatcaagc agattggtcg aatatttcga ttggtggaaa ttcggcaggt gcacaaatta
    10321 gtggagaata tttgttagca cttcaaaatg aagaaattaa aaaagctgat catcttgatc
    10381 cgactttgga gaacaagcag attacgaagt ttatttcttt gtctggtctg ttggatcctt
    10441 ctgcacttac tcaagtaagt gataaaatct ctagctttct ttatgaaaaa tgtggatggg
    10501 cttactttga taataaggac tttgaacaat cagagaaggt caaaagttta gccttggtca
    10561 gacatgcgga tcgttggacg caaaacacat tcttaacgga tggaaataca aatacgttta
    10621 cgaaacaaat ggaagaagta acttctgtat ttgagaaagc gggggtgaaa gtcacaaaag
    10681 tagattatgc ggagaaaaat gctgttttga accatgaata tcagtttgat ttcagcaata
    10741 aacaagcgca agaaacatat caaaagttag taatgttttt caaggagtaa agtcttatga
    10801 tgcaaaagag gttgtaatct gtcacttagc tccaagtcac aaggagcaat ttcaataaac
    10861 aagcttttca tggtttatga atattgtaac ttgtgactga ggagttagag atggcaaggg
    10921 gcacctttta ttcgaaattt gggaatatca cacgattatt gtcacgatct cttttacgta
    10981 aattttataa gtcagatttg ttgttttgat cgtttaaaaa aagcaacaaa tccgaagcct
    11041 gcggaggcaa gaagggacaa aaagccgagt ggtaagcaaa agaatgctgg ttccactaat
    11101 attccgttgt tattgatata aggctgggaa caaagatgaa tagcaaataa aatcaatgca
    11161 ctagcgaaaa aaagcaaaga aatatggata gctttcataa gcagcacctc cttttttata
    11221 attgtatgat aaatagatta agaatctata aatgtgacaa gtttgttagg atgtgaataa
    11281 aatgatcatc tagcgaactt gaaacaaaga tggctaatga taagcaatta atgattcagc
    11341 aatcagatag gtacaaagtt taccatcata cgtctagacc aataatagaa aatatgggaa
    11401 tataatagaa aagatttagg atacccccaa aagaatttcc ccaaaaattc gatgtatcct
    11461 aaactttttt attttacata acaatcatat caactgtgaa ataaaattac aaatgataac
    11521 ctaaaatgag gccaaaagcc agtgttatca aggaaatact taattcacca aaattttttt
    11581 taatttttta gaaaataaga aacaaaaata ataaaaaaaa gaaaagataa attttttact
    11641 actgtatact aactttgtta tcgcatctaa caagtaactc gaataatacc aatacaacct
    11701 tctccaaaga tgcgatgaca tacgttctaa cccaccgact attgatgttc tgtaccaccc
    11761 ttgcagaacc aaaaaagcca ctaccaaata tttggtagtg gctttttttg ttttatggat
    11821 ttttcgcttt ttctgttatg gtgctattct ttgatttcag aaatagtatg tcgaacttta
    11881 gcgatagaac gacgtgattc tttttcgttg taaaacatca aaatcacata tagagagtcc
    11941 aaaatgctta gttgagaaat acgggaagct aaagcttcag atcggaattc tgtttcttca
    12001 gaaatagaaa taaaaacgac atcgccaagt ttagcaaggg aagaattagc ttggctagta
    12061 ataacgattg tttttgctcc agtttttctt acggtttcag caatatggat tgtttctttt
    12121 gattgccctg tgtgagaaat caaaacagca cagtcttttt ccgtcaataa agaagcttcc
    12181 atcaattgaa tatggtaatc cgtgctgtga gaagttgcga taggggaacg caaaaattta
    12241 tgataagcgt cagttgctac aatctctgaa ccgccaacac cgaaaaaata gacacgttta
    12301 gattcattga taatagtagc cgcttttttt agatcctttt gttgtaacaa cttttttgtg
    12361 tcatttaaag ttgaaatact agactcgaac accttttgcg ccatagtgag ctcagtatct
    12421 gttttctgaa tattttcgtg gatagaaata gcagatagat cattttcttg gatcaacatg
    12481 gccattttaa aatctttaaa tccattataa ccaagttttt ttgtaaattg aaaaaaagta
    12541 gagtcagcaa tgcccagttc acttgctaaa ttgctaatag gactatgact tactttgctt
    12601 ggattttcta aaatataatc ggcgatagcc tgttcttttg ggctgaagtc gttgtacatt
    12661 gttttgattt gtagtcttat ggagacgctc atgagaattc ctcattttca taataagatt
    12721 atcatttttt ccgttctcat taatgttaaa gatacaagga gagtaggaaa aaatcaaaca
    12781 aaaaatattt ttgtaaaatc tatttacaaa aaaatttttt tgtataatga gggtataaga
    12841 aatggaggcg ctatcatgga aattggtgta attggtttgg gaaaaatggg attgaattta
    12901 gctttaaact taaaagagca ccatcacaaa gtacaaggac tcgacatttc aagtacagct
    12961 gttagtcagg caagagaaaa tgacattcct gcttatcaag agatctctga atttctagct
    13021 acttttgagc agaaaaaaat catctggtta atgcttcctg ctggagagat aaccgaaaac
    13081 atgttaagaa aactttttcc aaaactcgga ccaggagaca ttattattga aggcggaaac
    13141 tcttattata aagattcaat ccgtcgagca gaagagtttc agaaaaatga aatcggttac
    13201 ttggattgtg ggacttctgg aggaatcgaa ggagcacgac atcaagcctg cttaatgatt
    13261 ggaggagata aagaaacttt tctatccgtg gaacaattat tcaaagatgt agcaattgaa
    13321 agaggatatc tgtatgctgg tgcatccgga agcggacact tcttgaaaat gatccataat
    13381 ggaatcgaat atggaatgat gcaagcaatc ggtgaaggat tccaacttgt acaaaaaagt
    13441 gagtatgctt ttgacttgga acaagtcgca cgtgtttgga atcatggttc ggtgattcgc
    13501 ggctggctga tggaaatcat ggaagatcag ttaaacgaac atcccaattt aagtaattat
    13561 cggggaatcg tttctgcatc aggtgaagca aaatggacgg ttgaaacagc gctagaaatg
    13621 gctgttccag ttccagtaat tgcaactagt ttgttcatga ggaatctttc acaggaagaa
    13681 gatagttttt cagcaaaagt agtttcagca ctaagaaatg ggtttggcgg acatgaaata
    13741 gttgaaaagg gtgagtaaaa tgccagatta tcatatagca atcgttaatt ccagcagttt
    13801 cggaagagtc tttccacacc acttggaaag attaaagtca gttggagacg ttcatttctt
    13861 tactgttgat caagagattc caggaaaaga actagcggag ttacttaaag gattcaatat
    13921 cattattgca agtgttacgc cattttttcg acgagatttt tttgaaaaca aagatgaact
    13981 gctattgatt tcccgacatg gtattggtta caacaatatt gatttaaaag cagcaaaaga
    14041 acaccagaca atcgtatcta tcatacctgc tttagttgaa cgaaatgctg tagcagaaaa
    14101 taatataact aatttgttgt ccatgcttcg acgcacgaca caagcacaag caagagtcaa
    14161 ggacgatcga tgggaagatc gggcggagtt cgtcggtagg acgctgttta acaaaacagt
    14221 tggtgtgatt ggtgcaggaa ataccggaag cggagtaatc gaaattttgc gtaacggttt
    14281 tcgctgtgat gttctagctt atgatcctta caaatcagat ttatacatcg aaagctttgg
    14341 tgcaaaaaaa gtagaacttc aagaattact ggaacaatca gatatcattt gtttatgtgc
    14401 gaatttgaca gaagagaact atcacatgat ttctgataaa gaagtcgatc agatgaaaga
    14461 aaatgtttat ctatctaata gtgcaagagg cgctctagtt gatgaagaag cgatgattaa
    14521 tggtctgaaa agcggaaaga tcgcaggata tgccacagat gttttagaag aagaaccggg
    14581 acgtcaagat catccgtatt tagcgtttga acaagtagtg attacgccac atatatcggc
    14641 ctacacaagg gaatgtttag aagcaatggg tgaaaaatgt gtcagagatg tcgaacagat
    14701 cagtcagcac cttcttcctg aacgttctgt ccagacaaag agcaactata taaaaggatg
    14761 atgaagaaaa tggtgaacgg tttaaaagtg aaaacaggcc ctcaatttta tttatatgaa
    14821 gaaggtggta tttcaaaagt ttctgatctc ttgaaatcat acggcgcgaa aagagtactg
    14881 gtcacccacg gaacggtatc atgggaaaag gcgctaccta aattagtatt tttgaatgac
    14941 gaaacgattc aattttttta tcatcgttat tctggagaat gtagttatgc tgaagccaga
    15001 cgaatagcta caatcatcaa aaaaatgaaa tcgatttcgt agttggcgtt ggcggaggaa
    15061 aactgaccga tctagtgggt tatagtgcca atcttgcaag aatcgatttc ggagtcatcc
    15121 ctactttagc tagtaattgt gctccatgga cacctcttgc tgtcatgtat aaggagaatg
    15181 gacaagcaga agggaaaaca gaacactttt acagacaagc tgcttttttt ataacagatc
    15241 cccaattagt gattgattcc cctgttccat atttcattgc cgggttagca gatacactag
    15301 caaaatggta tgaatctgag ctcatcttag aacaagattt tttgcaagat gaatcatttt
    15361 tgaagctagc acaagatact gcgaagatct gcaaagaaga gattttgaat cattctgcta
    15421 aagcaatcca agatatggca caaagaaaac tgacatcgga gttcaaacag ctttcagaga
    15481 ttatctttgc tgttgctggt ttagttggag gattaggaga taaatacgca agaaatgtgg
    15541 cagcacatgc tatgcatgac gctatcagta aatatattcc ggaaagccat cgttttctac
    15601 atggagaaaa agtagcgtat gggattttct atcaactggc actagaaggt cgctgggaaa
    15661 aaatagacga gttatatcct ttgtatcggg aattagaact gccggtttct ctagaacaaa
    15721 tgggattatt tccgaaagat aaacagataa tagataaaat ggctgaattt attgattcga
    15781 aagagaaagt gcatttgatt cctatagagg taacacagaa atcactgata cagtcaatga
    15841 tggaactgga aggttatatc agaaagatct gaaggaggag gacacatgga aacattaagt
    15901 gtagtacaaa gtttgttgat tgctttatgg gtagccgcgg ttatgtcccg ctggttaggt
    15961 ggaggagcca cgttgacctt acgtttttct cctttgatga ctggattagt cgtcgggttg
    16021 atcatggggg aagttgcaca agcgatgatt gttacagccg ctttgcaaat gatttatatg
    16081 ggggtttttt ctccaggagg atcaatgcca gctgaaccat ctattgcagc agctatcgca
    16141 gtaccagtcg cattattagg ggatctgtcg ccagaagcag cgattgccgt tgcggtgcca
    16201 gtcggattgc tcggaagtta cttgtatcag tttcgttttt tcatcaatac ttttttaggt
    16261 aaatatacag acaaagctgt agaagatttg aatacaaaag ctatggcccg atcaattatt
    16321 ctttatccaa cggttgcctc atttttatta ttcgttccgc ttgttttcat tgctttatat
    16381 ttaggggcgc cattgatcgc tgatgtaatc aaagctttag agggaacagt cgttatccac
    16441 attcttgaag tagtaggtgg agggttagcg gcaatcggta tcgcgacaac tgtatacgtt
    16501 atcggtcgaa aagattatct ggtctttttc ttccttgctt attttatgag tgttgttttg
    16561 aaatctttag atattacgat ggttacttat gccatttttg ggattattat cgctttgatc
    16621 tttgtccagt cgcaaaaagg gaaacaagta cagcctgcca caagcaataa caattcagca
    16681 tcttttgatg acgaagatga ctatgatgac ggattttaat ttaggaggaa tgggaaatgg
    16741 ctgaaataat ggataatcaa acaggtgctc ctgaagaaat cacgaaaaaa gatgtaacaa
    16801 aagcctatct gagatggcat tttgcaaacg aaattcctca ctcttttgaa cgttacttgg
    16861 cgccatcact actatacgga atgatgccaa tcttgaaaaa actttataaa gatgaagact
    16921 ctttaaaagc agcatataaa cggcagttac tgttcttcaa cactcaatta agctggggtg
    16981 gcggtgtgat tactggccta atgtcttcta tggaacagca aagagcagaa gaagagtatg
    17041 aagaaaaaga gatcttgatg caggatgact tgatgtataa cacgaaagcg ggattgatgg
    17101 gggcactagc aggaatcgga gatgcaatcg attcaggaac cgtccaatat atttttatcg
    17161 caatcgcggt accttgggca caacagggaa gtcctttagg cgcacttttt ccttttatct
    17221 gctttgggtt gtatcaggtt ttactagggg tatttttcgc aagacaagct ttcactatgg
    17281 gccgtaatgc tacaggccta aagcaaaaca ctggtgttca gacagcgatt gaaatgctat
    17341 cagttttagg gttgtttatg atgggggtgc ttgcgggaaa ctatgtaaaa gtagaatctt
    17401 cattgaaatt tgcgatatcc ggacgtgagt ttgttatcca ggaaattctt gatcaaatcg
    17461 tgccagggat attaccttta gctgtcgtaa tgggtgtgta cttgttctat acgaaaaaag
    17521 gattgaaagt cacacaagca ttattatggc tgactggaat attaattgtg ctagcaggaa
    17581 tcggtatttt ataaaaagaa gggaacgtga ataagatggg tgtagtcaat ttagcgcgtg
    17641 tggatgagcg tttgatccat gggcaagtaa tggtaacgtt atctcaaaaa agtggagtga
    17701 attccatttt tgttgtagac gaagttgtag caaaagataa atttatgaga gatctttaca
    17761 aaaatgcagg aagccgtaca ggacaaaaaa caattgtcat tacaccagag aaagctaaat
    17821 tctattggga tgaatatcaa tttaaagaat acaattgtat tttgatcgca aaaacagtcc
    17881 aaacgattta cgacttagta aaacacggaa tccccatgga agaattgaat attggaggga
    17941 ttgctcaaaa aaatcctgat acagatcttt tagtgacgaa atctgtttat ttaaataaat
    18001 cagatgctga aaaattgaaa gaaatgaatg aacaatatgg cgtaaagaat atttattttc
    18061 aagccactcc atctgcacct aaaacaggat taaaagatgt attgaacaag tttgatttgt
    18121 cataaacaaa tgcttagaaa aaagataaag agggcgaaaa aatgaagaag aacgagctgt
    18181 ttcgtgattg ggaatttcgt tatcgctata tttaccgtaa gcgccgtaca aaaaagagta
    18241 aacagcgttt tctttcagca ttagtatcag atatttacag tatgagaaca gatgtgacag
    18301 tcattgctta cgatacgcta gcctaccgat caaaaaatat ttatgttgga gatatcgaaa
    18361 aagcagagaa agttatctgt acttattacg atacacccgt tcatgcatta ggaagttatt
    18421 tcatgtttga ttggaaagac caaaggaaaa aaacaatcta ctctatatta ttgtccttca
    18481 ttttgttgtt cagtttgggt tggtggggaa tgatgatata taacaaaaat cctcatcacg
    18541 tattcgatct gctatccgta taaacaggta tcactgtact agcatttggg agctactttt
    18601 tcttattggg aaaagcagct cgcggatggc ctagcagaca aacttttatt cgaaatactt
    18661 catccatatt aacgatgcta gaaatgatcc gtacgattga tgatccgagt gtagcgtatg
    18721 cgtttgttga tgaaggctgt tatggagaaa agggcttaga cagcgtgaga tcgggtatga
    18781 aaaaagaggc tattcttttt tatctagact ctgttggggc agatacaccg ctacagtttt
    18841 cgggaaatta tttttcaaat aaagaacagt ggctgaaaca agttgataag ttgaaagaaa
    18901 aaaacgtcaa ttatattttt agtgcaagaa aaaagcaagc gcagttcttc tatttgacca
    18961 aaacagattt acgagggaaa acatttaatt ggcaaaatgc caatcagatt attgctcttt
    19021 ttcgataagt aaaaagtgca aaacaaggag tgagaagact aatgttggaa atcatgatcg
    19081 ttacacatgg taagttgagc gaaggactga aagatgcggc ggaagtaatt gtcgggacat
    19141 cgagccatat tgaaacaatg tgcttagagt ctggggagga catccaaaca ttcggagaga
    19201 aggtcaaaga aaaattaact atgatcaaca cagcagaacc catgctagta tttgttgatc
    19261 taattagcgc aagtccgtac aatcaagcgc tcttggcagt caatgaactg actgaagaaa
    19321 agaaagcagc cacttatgtc atagggggcg tgaatctgcc aatgttgtta gaagcaatca
    19381 atcatcagat gcttcacaca ccgatagaag aagcggtgga acaaattgtc aaacaaggaa
    19441 aagataattt aactgtttgg catgcttcag cggaagaaaa aaaattagat gaggacgatt
    19501 tttagaagga aggctgaaaa gatgaagtgg ggatttagat ggtatggtga aaaaggggat
    19561 tcgatcccat taaaatatgt tcgccaaata ccgggaataa atgggataat tggaactttg
    19621 ctgactaaaa tgcctggaga tgtttgggag atttcagaaa ttgaggagtt gaaagcatct
    19681 gttgagagcc aaggactgga actgcttgga attgaaagtg tagcgatcca cgatgcaatc
    19741 aaggcaggga cagatgaacg agattactat attgataact atatacgaac aatcaaaaac
    19801 ttgtctcgat gtggggttcg attgatttgt tatagcttca aaccaatttt tggatgggcg
    19861 aaaactgatt tgtttaatga aaacaacgat ggaagctatt ctcttttata cgatcagaaa
    19921 atcgtcgatc agatggagcc aggagaaatg tatcaattga tacacagcca gtcaaaggga
    19981 ttcaaattgc cgggttggga agaagaacgg ttgaaaaaat tcgctcagct ggaaaaactg
    20041 tatgaaggaa tgaccgaaga agaattattt gaaaatctga cttatttttt agaaaaagtg
    20101 attccagtgt gcgaaaaagc agatgtaaaa atggctatcc atccagatga tccgccatgg
    20161 gaactttttg gttttcctag agtgacgaaa aatcttggcg acttgaagaa aattctaaat
    20221 gcagtagatt ctccatataa tggactaacg ctgtgcacag gatctttagg ggcaaatccg
    20281 gaaaacgatt tagttgaaat catccatgag gtaggttcgc gcatccattt tgtccacttc
    20341 agaaacgtgg agtttttagg agaaagaaag ttcaaagaaa cggcacatcc ctctacagaa
    20401 ggctcccttg atatgtatca tattatgaaa gcgttggtgc aagaagggtt cgacggtcct
    20461 atacgccctg atcatggtag aaccgtgtgg ggtgaagtgg ctatgcctgg atatggcctg
    20521 tatgatcgtg caatgggact cacttacatg caaggtctat atgaggcgat aagtaaggaa
    20581 aaaccactgg gagagcatta tgaataaaat caagctcttc atctttgata tggatggcct
    20641 tttattagaa actggacgtt tagcttatcg tgcttatgta aaatcagcac aaaagtatga
    20701 ttatgaaatg cgtaaggaag tctattattt actaactggc caaacagaaa tggcgataag
    20761 agaacaaatg ggcattttgt acggagaaga tgttccatat atcaaatggc gagaagcaat
    20821 caatcaatat aaagaaaaaa tcgtgaaaga agataagaga gtatatacga aaaaaggagc
    20881 agaagaaatt ttatcttttg caaaagaaag aggaatccat acaatcgtgg cttcgtctaa
    20941 tacacgggta aaagtagaaa tgtatttaaa aatggaaaat ctatatgcct tgtttgatca
    21001 aatcatttca ggggatgatg taaaaaaagg aaagccggaa ccagagatct ttttgaaagc
    21061 ttgttcaaaa atgaatattc ctccaagtga agcacttgta tttgaagact cgattgcagg
    21121 gatcgaagca gcaaggcgag cgggcatttt gtcttttctc atcaaagatc atttgatagg
    21181 gttgcccgat cataatggga agcataagtt gaaagtagat gtaagtttat atgaatccaa
    21241 taaagcagac tatgaatttt atgacctgca tcaagcaaaa cgatttttag aaagtaaagg
    21301 gttgtatctc taataaagag gactattttc tagtcctctt tatttattgt cctgcacgac
    21361 tgagggaaca gatgaaaaag aagtaatttt ttattttgaa gtatctacct tatttgtagt
    21421 gaacaattta gaacaaacac aaaacgcatc tactgtt
//
LOCUS       DACGMI010000052        20801 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.054, whole genome shotgun sequence.
ACCESSION   DACGMI010000052 DACGMI010000000
VERSION     DACGMI010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.054"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..300
                     /locus_tag="IXT46_002152"
     CDS             <1..300
                     /locus_tag="IXT46_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4948053.1"
                     /translation="DGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKEN
                     RKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(724..894)
                     /locus_tag="IXT46_002153"
     CDS             complement(724..894)
                     /locus_tag="IXT46_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4948054.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1088..1267)
                     /locus_tag="IXT46_002154"
     CDS             complement(1088..1267)
                     /locus_tag="IXT46_002154"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948055.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            1654..2766
                     /locus_tag="IXT46_002155"
     CDS             1654..2766
                     /locus_tag="IXT46_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4948056.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(2844..3137)
                     /locus_tag="IXT46_002156"
     CDS             complement(2844..3137)
                     /locus_tag="IXT46_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAQ4948057.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3305..3619
                     /locus_tag="IXT46_002157"
     CDS             3305..3619
                     /locus_tag="IXT46_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAQ4948058.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3640..5619
                     /locus_tag="IXT46_002158"
     CDS             3640..5619
                     /locus_tag="IXT46_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4948059.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5632..5958
                     /locus_tag="IXT46_002159"
     CDS             5632..5958
                     /locus_tag="IXT46_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAQ4948060.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            5974..6492
                     /locus_tag="IXT46_002160"
     CDS             5974..6492
                     /locus_tag="IXT46_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948061.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6492..7844
                     /gene="celB"
                     /locus_tag="IXT46_002161"
     CDS             6492..7844
                     /gene="celB"
                     /locus_tag="IXT46_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAQ4948062.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(7928..9433)
                     /locus_tag="IXT46_002162"
     CDS             complement(7928..9433)
                     /locus_tag="IXT46_002162"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAQ4948063.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9525..10115)
                     /locus_tag="IXT46_002163"
     CDS             complement(9525..10115)
                     /locus_tag="IXT46_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4948064.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10294..11940
                     /locus_tag="IXT46_002164"
     CDS             10294..11940
                     /locus_tag="IXT46_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4948065.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            11989..12708
                     /locus_tag="IXT46_002165"
     CDS             11989..12708
                     /locus_tag="IXT46_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAQ4948066.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13187..14134
                     /locus_tag="IXT46_002166"
     CDS             13187..14134
                     /locus_tag="IXT46_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4948067.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14146..15066
                     /locus_tag="IXT46_002167"
     CDS             14146..15066
                     /locus_tag="IXT46_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4948068.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15107..16564
                     /locus_tag="IXT46_002168"
     CDS             15107..16564
                     /locus_tag="IXT46_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4948069.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            16909..17523
                     /locus_tag="IXT46_002169"
     CDS             16909..17523
                     /locus_tag="IXT46_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAQ4948070.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17516..19240
                     /locus_tag="IXT46_002170"
     CDS             17516..19240
                     /locus_tag="IXT46_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4948071.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSIAFKEG"
     gene            19237..20688
                     /locus_tag="IXT46_002171"
     CDS             19237..20688
                     /locus_tag="IXT46_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4948072.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
BASE COUNT         6705 a         3511 c         4169 g         6416 t
ORIGIN      
        1 gatggcttag caccaggagc atatcagctg gtagaaactc aagcgccaac ggggtatgaa
       61 ttggatgcga caccagtaac tttcaagatc gaaaaagaac aagaagtggc gatcttttta
      121 acaaaagaga atagaaaagt tgctgatagc tcagatataa gaggaaacaa tccaacaagc
      181 agtggaaata agcatcttcc aaaaactgga gaaaccatca ttagccagtt tatattgtca
      241 atattgggtg tgctacttgt tttcatcagt ataaaattta gaaagaaacg aaatatatga
      301 gctaaaataa aaaattgaat aagcatagtt tttaaaatca actagtaccc atcaattgaa
      361 tggaaactac cgattttaga aggggtatac aaacaaatat tagtatcgga gtagagaagg
      421 ttgaacccaa ccagtaaata agtaaagaca attttgtgct gcgttgagaa gtgaaaaata
      481 aacctttgta gtaatactag ttaataaaaa atatacaaaa acactgcgaa aatcattctt
      541 gagtttcgca gtgttttttg cctaatgact caagtttatt gggtaatact ttgattttct
      601 ttctacaaat aatcagcgat cagttgtaat tttttctcta gttttaatgg ctctttgtca
      661 ataaggagaa aaacaagtcg ggtcttttgt ctcggaaagc ttcaaccaac tcgtgaataa
      721 aggttacgcc tccttgaaag gcgtggaaaa accaagtaat cgatcaatca ccaatttcgc
      781 atttggtaga acatgtttgg tgagctgaaa gtaggtggcg ttcatgtctg taactaagaa
      841 ttctatttct ttaggattag tgcagctaag gaaatagttt gttaatcgag gaattttttg
      901 tgtaggtaaa ttttctcgat taatttttct gtctcgccat ccgcggaaat aaaactcagt
      961 ttatcctcaa cggaaacgtg agaacgaaat tcacaaccct caacactcaa gacagaattc
     1021 ttttggaaga ctttggtaaa tagcttctca actctttcaa tgtgcgaata acggttgtca
     1081 aagataccta acaacttttc gaaataaaaa ataacgacac tttttcagtc agtaaagaag
     1141 tgattttatg tctgacatga tttgaaatcg agtgccttgg acggataaaa taactttgag
     1201 cgttccaatg gcttcgacag tttttacagg tatagcgctg cttttttagg cgtataacca
     1261 ttggcatatg attatattat tcaaagtgga caatggtttc cttcttcttg tttttcacca
     1321 ccattaattt cctatttcca tctaccacag cagaaccaca atttctacag acacatggag
     1381 cagggaagag aactgcagca acgatcaatg tttttttctt ctgtaaggtt tcgtaagaga
     1441 cctctgtaat catcaaattt ttgtctattg atctcagaat ttttttgata gaaccattca
     1501 taaagcatat cgttctctca gttgtttatt ttgtggtgat ttaatcatac aagaaaacga
     1561 tatgtttttt tataaaaaca tgaataggaa aaatagttga caagaaaatg acaacgccat
     1621 atgatgttcc atagtattta caacctgtca tagatgactg taaaaaataa aagtaaaaag
     1681 aaaggacgac aacaggtgga tttttatcag tctctacaac tagatccgtt tattttaaaa
     1741 caaaaaatac gagaagcagc ttctaaaaaa gaaaagtgca tgtatatttg ttcattgttt
     1801 ttacgatcat tattcatcgt attgtttgcc atttgtttta tcattataat tacaacatta
     1861 tttgaatcga agcataaacc atacgctgtg gttttattct gtatgttgat gagtattcgt
     1921 tttgttgact ttggttataa gatttcccat tcgatcatag gtttagcaat cgtcatgttc
     1981 tcactattag tagcaccgta tgtccagctg atcaaatggt cagttatggg catgttgatt
     2041 cattttattt tactaagcag catattaatg gcaaccgcta gtgatcccaa aatggggaat
     2101 gcttctttgt acggcttttc atatctcttt attgtttatt cgttacctaa agattcgttg
     2161 aacaagaatt tctttacaca aacaagtagc ttattatttt tgtttttttg ttggttttca
     2221 gttctccttt acagaaaaca tcgagaaaag aacaaagaca aaagcttgtt taaagagatt
     2281 tttttgaaag gcatgtattc gcaggaaaaa atttggatgc tcatctatgc atttggcatt
     2341 agtcttttga tcgttgcagg agagtatgtc ccttttcagc gattgatgtg ggcagggttt
     2401 gcattttctt ctattgtatc tagctatgga ttgatgtcga ttggtttcaa agaacgagca
     2461 gtagaccgaa tcattggctc attgattgga tgtgttttat ttattggtat cagccaattt
     2521 attcctttta actgggtcgg tatattaggt ggtctagctt taggtgtttg ttctacctat
     2581 agatataaaa cagtttttaa ttcttttggt gctttggcaa tcactgccag tttattcggg
     2641 gttccaggag cagtaacgat ccgcattttt gagaatatcc ttggggtatg tttaggaatc
     2701 atgtatattg gggtgactga aatacttatc cgaaaaataa gagaaaaaca cggtttgaat
     2761 cattagatga gatcgaataa aaaataagga aaaagtgaag atacacatgg atgataaatt
     2821 gctatcattc catgtgtatc tttttacggt aaatcagtga aacgttcgac tttcattttt
     2881 aatttatact ttttacggag ttcgtttatt tgagccatca tttcggattt gtgatgcttt
     2941 tcgattgctt cttcatcttt ccaacggtcg atcagtaaaa gagattctgg atcttctagt
     3001 ggaaagtaat agtcatattt ctcgtttcct tcttctgcac gaatcgcttt gacaatgttt
     3061 ctttcgacca tttcttctgc aaattttctg gcttgtccat ttgtacttgt atacaaaata
     3121 ttcactgtga tactcactaa atcccctcct gaaaaaattc tatcactagt atatcacggt
     3181 gccagaaatt attattcaag atatgataca cattttttcc gcaatgctac ggaaatatat
     3241 attttgaata gaaaacgctt acaagatatg cttggtttat aaaaataaaa ggagtgattg
     3301 atttatgaaa aaagcattga ttatttgtgc ggcaggaatg tcatcctcga tgatggcctc
     3361 aaagacaacg gatttcttta agcaaaaaag agaagaggta ctcgtagatg cagtttcagc
     3421 tacagaaggc gataatatga ttaagaatag tgattttgat ttatttctga tcagcccgca
     3481 aacgacgatg tttttggata aattcaaaaa attaggagaa tctgttggaa agcctgttgt
     3541 tagtatccct ttccaagcgt atgtcccaat ccctacaggc atccagaagt tagcagaggt
     3601 gatcgaagag aacatatgat ggaataggag tggatgataa tgaaacagaa ggaaaaattg
     3661 ctgttgagat atttgattga tcacaagaag gagtatgtca ccagtcaacg tttagcttct
     3721 gaattgttat tatctgatcg gacaatccgt aattacttgc agcggatcaa agagttagta
     3781 gaaaaaaacg gaggtaagat cattgctaaa ccaggttatg gctaccaact gcatatttta
     3841 caaagactga catttgactt gtttttgagt cggcaagaaa tagtacctgg atatgctaga
     3901 gaaccgcaag gattttatga gtccgaagat cgacaaaagt atatattgaa ccaattgctt
     3961 ttggaagatg ccattctttt tatggatgat ttggcagaag agctttatat cagtcgttcc
     4021 agtttgacaa aggacatgca agaaatcaag gagcgattga ttccatattc actaaaaatc
     4081 gtttctaagc atggtcaagg gacatggatc gaaggggaag aaagaaatcg acggcatttt
     4141 atcatggata ctttttttgg aaaccattat ggaaattcat tgaaagaata tttagggcaa
     4201 agccgttttt tcccagacat cagttttgaa gagctagtca ttatcattct cgatgaaaca
     4261 agagaagcta agttaaaagt ttcggatttt atcatacaga atctgacttt acacttggct
     4321 ttggggatca aacggctccg agaagggttt gaaatcaagg aattaggcat cgaacaagaa
     4381 gtttctaagc gagtagagta tcaagtggcg cagcggatcg ttcaacgtat tgaggtaatc
     4441 gcaggtgtat cgtttcccga agaagaaatt gcttatttga cattacatct catggctaag
     4501 tcgaatcaca aagaaaatca aaatgatcag gaactatcaa aggaattagc gaaagttctg
     4561 aaaagattgt ctcaggaatt tcatttttca ttagtagagg atctccagct tttcaatgga
     4621 ctactcgatc atttgtcacc gatgatgatt cgattgagcc gaggtattcg cattgagaac
     4681 ccattgactg aggagataaa gaaagaaaat cccaaagtct ttgacgcagt aaaaaggcat
     4741 ttcagcaaca tgccggcttt gaaaaactat accatcaatg aagatgaatg ggcctatttg
     4801 gctttgcatc tcatggcggc attggaaaaa gaaagagctg cgcataaact acatgcattg
     4861 attatctgtg caacgggtta cggcagtgcc caactattaa agaatcgcgt agtcagtgaa
     4921 ttcggtaaaa atattacagt ggtaagtgta aaaggctatt atgagatcaa tgaaacaact
     4981 ttaaaaggaa tcgacctgat tatttcttct attgatcttt cgacaatgtt tttcaaaatt
     5041 ccagttttac atgtcagtat ttttttgaat gaagatgatg ttcgtaaaat acgaaaggta
     5101 gttggagaat ctatacccta tcattcctca gatagaccga taccagcatt ttctctacag
     5161 caaaaaaagc agatttacac cgaacagttg tctgaaaaat ttttcaagac ttatacgtac
     5221 gaaccgaaaa aggaagaaat tcttcatgat ttgctgcaaa agctgagcat aaatgaagaa
     5281 gaaggatata taagagaaat gcgaaagcag atccagcaac gtgaaaatat gggacaaatc
     5341 atattcagtg atacagtggc agtcccacat cccgctgttc cagttggaat cgaaacaaag
     5401 gtagccgttg cattgattcc ttctgggatg cagtgggatc aatatcaaga aattcatttt
     5461 gtttttttag tttcgccttc ttatgtcgaa aatgaaggaa ttacggtcgt gactaaagca
     5521 atcgttaggt tagttgacca gctaaaagta cagcaggaaa tcttagctga acctattttt
     5581 gagaatttca gcagtaaatt tatcaaactg atcgaataag gaggaaaaca gatggctgaa
     5641 aaaataaaca gtgaaacact acaagtgact tcttttgata tcattttcca tagcggaaat
     5701 gcacggacac tgatacatga agcatttcgc tcgatgcgta aagagatgtt tgaagaagta
     5761 gaagagaagt tgcgacaagc aaatgaagag attcttcatg cgcatcagtc acaaactcaa
     5821 cttctgaaag aatatgccag cgggacaaaa atagaaatgg aaattatcat ggtccatgca
     5881 caagatcatc tgatgacgac gatgacatta ttggaagttg cacaggaaat gaattatttg
     5941 tatcaaaaaa ataaatagaa aggaaggatc attgtgcagg atacagtaaa aaggaaaatc
     6001 gaattagaaa aaaagcaact tagtttgaaa aacatgtatt tcaatcgtta tctaatcgta
     6061 cgttacctga ctgccttttt ctttttcatg aacatgcaat ggatgattct gcttctatca
     6121 gctaaaagtt taggaagtag tttaccgatg attctgattt tagctatttt gcctgcagta
     6181 ggagaacaag taaagcttta tcgaaaacac caaacgaacg ttccatggac aaagtggtat
     6241 tttttgttcc agagtgtctt taatttatta gtgattccag tgttgtttac ctcaggattt
     6301 acattcttgt atccttttat ggcaaataac aatggaggac agttatttgt tttcattctt
     6361 gttgtaagcg gtatttttgc cagtgcattt atacagtatc gtttaaagaa aatttcactc
     6421 aaccaagacc aacagtatat ccgtattaaa caatatgaaa aagcgttata tttaggaaag
     6481 gagaataact aatgtttgat tttttgcaga aatacctgat gggacctatg gggaaaattg
     6541 cgcaacttaa aatcgttcgg gctgtcatgg cagcggggat ggcttctatt cctttcacga
     6601 ttgtaggctc gatgtttttg gttttaaata ttttgccatt accgttccca tttttagaag
     6661 gattttttaa tgcaactttt ttcaaagtta gtgacttgta catgatcgtc aatacaatga
     6721 cgatggggat tttatctatt tactttgcca ttgtgtttgc ttatgaatta acgtcaattg
     6781 aacgagatga acaaaaatta aatgttaatc cgctcacggg ggcattacta tctgtttttg
     6841 cattctttat gtgtatccct gaattgatca tgactgatgg taaaatcagc ttgattgctt
     6901 ctatcaatga gacagaaact gtagtaaatg gtattaggat gggctctttt gtcgaacgtt
     6961 taggaacttc aggaatcttt acagctatta ttatgtcgat tattgcggtc gaattgtatt
     7021 gtatgtgtgt caagagaaat tgggtcataa aaatgccaga tgttgttccg ccgggagttt
     7081 ctcgttcttt cactgctctg atcccaacat ttgtcattgc gtttgtggtg atgatcatca
     7141 atggattatt agttgcacta ggaacggata tcttcaaaat gattgctatc ccatttgggt
     7201 ttgttacgca gttgacgaat acatggcttg gtgtcatggt gatttatttc ttgatccatg
     7261 cattgtggat cgtagggatc catggagcga atatcatcac ttctttcttg accccgatcg
     7321 tattagctaa tatggcagct aacgcacaag gcgcaaatta tccgttggca ggagaattca
     7381 acaattctta tgtaaccgtt ggtggatcag gtgcgacttt aggattgatc atctttattg
     7441 cattcctcgc gaaatctgat cagctgaaag tgttaggaaa agcctcactt gtaccaggat
     7501 tattcaatat caatgaacca atcattttcg ggatgccaat cgtctacaat ccctatttag
     7561 cggttccgtt tttcttagct ccgatggctt ctgctacact cgcttatttt gccattcggc
     7621 tggaaatcgt caaaccgatg cttgcacaga tgccgtggcc ttcaccagtc gggatcggag
     7681 catttgttgg tagtggtggt gattggaaag ctgctgtgtt agcagtcatt tgtgcaatca
     7741 tcgcattcat tatctggttc ccatttatca aattctatga taataaatta ttaaatgaag
     7801 aaagagaaaa ggcagcagaa ttagctagtg aaaagttaaa atgatttcta agaaaaaagg
     7861 aactgtgaca aaaaatcaca gtcccttttt ttcttagaaa tgggaaacca ctagtatata
     7921 aataccatta ttcttcaatc aaccgcttca cgattgcata atccccttca taaggttcat
     7981 ctacaccatt gattttttga tagggatcca cgccttttcc cgcaataacg actgaatctt
     8041 gcggagcgct ttctgctaaa gcgcgtcgaa tcgcttcagg acgatccatt tcataatgaa
     8101 cgatcaaatc tggattagta attgcttcat tgatttcttc cgcgattttt ttcggatctt
     8161 caaatgctgg gtcatctgcc gtcaaaaagg cgatgtcagc tgtttctgat agcacttttc
     8221 caaaatcatg tcgacgggag attgctttgt ttcctgggct gcctaataca acaattacac
     8281 ggccatctgg atgttcattt ttggcaaatt ccagcaatgt tttcaagctt agataattat
     8341 gtgcatagtc cacatagaca tgcgctccat tggattggat caattgatcc attcggcctg
     8401 gtacacgagc ttcttttaat ccgtcttgtg catcttgact ggaggcacct gttagtgctg
     8461 cggcaatgat cgcactggct gcattttctt ggttgaatcc tccagccagc aaaatatcat
     8521 aagcagtatc gcagatagct aagcgatctt catgagaaga taaagtaaaa ccgtgagtac
     8581 ctttatctga acggatcact tgataattgc tttcttccga acgaccataa gtgatcgttg
     8641 gaatctggaa tagatcggct gtttccctaa gtaaatcaaa atagtcactt tcatgattta
     8701 aaacaactgt ttttgaattc aagatcaatt gtcgcttgca atagaaatag tcatcaaatg
     8761 tcggatgttc gatcggactg atatggtcag gcgagatatt caagaagatt ccgacatcta
     8821 aagtcaagcc gtatacgcgt tgtgttttgt aagcttgtga agaaacttcc atcactagat
     8881 gagtcatacc attttcaact gcttctgaca tcatacgata taaatctaat gactcaggcg
     8941 ttgtcaaatg ggatttgaaa tatgttttgc catctaacgt tgtattcata gtagaaagca
     9001 atgctgtttt tttatttgtt gtgtgatcca agattgcttt tgtaaagtac gcagcagttg
     9061 ttttaccttt tgttccagtg aatccgatca ctttcaattt attttgcgga tagtcgtaaa
     9121 aagccatagc aagaagcgcc attgctttac ggatatccgt tacgatgatt cctactgctg
     9181 aattttcgta tggttgttct gatacataat attgaatacc ctgttcgatt gctgaatcca
     9241 aatattcttc tttgaaattc attcctttac agaaaaacaa agtagaagca tcagcttttc
     9301 ttgaatcata acttaactga agaaattcag ctttttctgg tacatcaaga tgccagcctc
     9361 ttgttgaaac aaattctttt aatagatttt cttttaatag taaatgacgg atgtcttcta
     9421 aagagaagct cattgattga tccctcgctt tattcaattt cttggtttat tatagcacac
     9481 tctttttaat atatcgtttg tttccgctat gacaaaatcc agctttattc aaattttctt
     9541 gacacagggg acaagcggat gagtattttc ataaacaatg aactgactgt aatagatagg
     9601 agaacgaata gtgtctccaa caatccaaaa acataataat tcaaaaagac gataagacta
     9661 ttggtaagta aaagtccttg cggcattgga agccgaaaaa atttgtggaa aataatcggc
     9721 ggtatcgtta taccgccatt tgaggccccg actgtgtaca atgtgtaaac cccaagactg
     9781 aacaaaagac ttcctgaaat cagtgaaaag aaatgtgagg agatcatttc cacttttgga
     9841 acaatctcta aaacaacagg aaaaagcaga cttcccgcta cagtcttaaa aaatactgat
     9901 tttcctaata ggacagcggc tagaagcagc atcataagat tgatgctcca aacagtaact
     9961 gagcgttgga tagaaaaggc cgtttcaact aaatgtccga tggcgcccac tccggcggaa
    10021 gctatatcgt gagggagcaa gaaccaattc aatccaactg tgataaagaa aagacctaaa
    10081 aatataacgg gtagtttttt tatttcttgt gtcattgata tctcctataa atgttagcca
    10141 taaaaggctg tatatttctt tactttacca aaaaaacgaa accgaattca aaaaaacaat
    10201 tgttcttata aaagttatat aaaatcgatt gccagtttct gttttaccaa ttaaaatgat
    10261 agtaatgttt tgtagaaagt tggaatctga ccgatggata atcaaagaaa accagcatta
    10321 gatcaattaa caccgcaaga aaaaatggca cgaggctctg cttggatgac cgccagtaat
    10381 atcatttcaa gattgctagg cgctgtctat atcattccct ggtatgcttg gatgggcgaa
    10441 aatgctaagg ctgccaatgg attattcaat atgggataca atatatatgc attgtttcta
    10501 ctgatctcta cagcaggaat acctgctgcg attgcaaaac aaactgcacg ctataattca
    10561 ttgaatgaat atggcacttc acgacgatta tttatccgtg cattacagat gatgggcggg
    10621 ttaggcctgt tgtttgcttt gttcatgtac atcgcctctc cttggctagc tcatgcttct
    10681 ggtggcggag aagaactgat tccaacgatg cgttctttga gtatcgctgt attggttttt
    10741 ccttgtatga gtgtgatacg agggtatttt caaggcaatc aagaaatgat gccttatgcg
    10801 ctgtcgcaga ttgtagaaca ggtggcacgt attttttata tgctattggc tacattcatc
    10861 atcatgaaag tcatggatgg tgactatgtg acggcggtca cgcaatcaac tttcgcggca
    10921 tttatcggta tgctagcaag tattcttgtc cttttgtatt ttttgaagaa acatcaagcg
    10981 tatacatcgg cgtttattca ctacagcgaa aacaaaataa atattgcaac gaaggaattg
    11041 ttgttagata ccgttaaaga agcgattccg tttattattg tgggttcagg ggtaacgatc
    11101 ttcaaattag tcgatcagtt cacttttatg aagatcatgt ctgcatccac cgagtattcc
    11161 aatgcacagt tactggatct tttttcgatt tttagtgcca atccagataa gttgacgatg
    11221 gtagttattg cattggcaac atcgatcgcg tctactgggt taccgttgat tacagaagct
    11281 gttacgttga aagatcgagt aggtctggca aaattgacaa gcggaaattt acagttgttt
    11341 tcatttttta tgtttccggc gacatttggt gttatgttac ttgcctatcc gctaaataca
    11401 ttattttata caccggattc tctaggaagt aatgtactga tccaagcaag ttttgtagga
    11461 ctcttcctag gactatatat gctagtttcc aacatgctgc aaggaatgtt tgaaaacaag
    11521 gcggcaatta attatttggt tattgggttt ctagtgaaac tccttcttca atacccagcc
    11581 attcgtttat ttgaagtata cggcccttta ttggcgacaa tgatcggatt tgctgtgtct
    11641 tgtaccttga tcttaaagag aatccatgaa gtagcccgct ttaaaccaag ttttgtctgg
    11701 cgcaggacat tgctgatctt tattcttacc ttgattatgc ttttggcttc gtggatcaca
    11761 aagatgattt ttggtgcttt tttaaacgaa gatagcaaat tccagtctct attgttgatt
    11821 cttgtagtag caggtatagg ggctttagtg tatggttatt tagctttgaa aatccgcttg
    11881 gcagaaagac tactaggacc aggaatagcg cgtttacgac ataaattaaa aataaaataa
    11941 gtgaatcaga agagctagat tgatgctctt ttgaaatggg ggaaacgcat gcgtttagat
    12001 aagtttttag cagatatggg acttggcagc cgcaaagaag tcaaaggatt gatcaaaaaa
    12061 ggaacgatcg aagtcaatgg acaagtggtg aaaagcgata aagcgcaagt aaatgaattc
    12121 gaagatgcgg ttacttattt aggagaaatc attacgtatc aaaaagattt ttactacatt
    12181 ttgcataaac ctgcaggagt catttctgct actcaggata atcatgatca aaccgtaatc
    12241 gatttattgg aagaccagga ttatcgggaa gatctttttc cagtcggccg attagataaa
    12301 gacacagagg gcctcttgat tttaacgaat gacggggtgt ttgcccatca gttactatca
    12361 cctaaaaaac atgtggagaa agaatatcta gctgaggtta gcggtataat gacagaagaa
    12421 gatatccgtt tatttgcaga aggactgatt attgatggcg atgagcagac attgccggca
    12481 aaactccaaa ttgatcaagt agatcaagag acagaaactt caattatccg tctgattttg
    12541 catgaaggaa agtttcacca agttaagcga atggtcaaag cagtaggaaa agaagtctta
    12601 tatttaaaaa gaatccgtat gggaaaattt tggctgccta aagatttgaa taaagggcaa
    12661 tatcgaccca tgaccaaaga agagctagaa caagtgagag aaaaataatt gaatggatag
    12721 ctaaaagaat aagcagagta gttgtagcgc catctgaaaa gcagacttgt ccgtctgact
    12781 ttcggatggc ttttttgtga aatttcggct tatttccgta gaagctactt ctggaacacc
    12841 gtttgttcgg aataagggac tgtgacaaga cttttgttac agtccccatt gttccttgtg
    12901 actcagagtt agatagtaag gacacgatct ccctaatact caggccaaaa cgctgaattc
    12961 acaacctctg ataaacggtg ttcaatcagc tgaccctcgg tattagctca aaaaacggca
    13021 aaatatgagg aactattttc ccgttttttt ctctaatact caggccaaaa cgctgatttc
    13081 acaacctctc ctatactttg tttcattttc cctatacttt gtttatttat tctcattatt
    13141 gaaagcgcta taattacgtt gcgaatgaat cgaaaggggt ttttagatga aaaaacgaaa
    13201 ggggttcaat cattttttta tgaatctatg gcgttataaa gcacttgtcc tgatggctgt
    13261 accgggtatg ctttggatga tttttttctt ttacatacct gtaatggcga atgtcgtagc
    13321 attcaaaaat tttcatattt cagcagatgg gttcttggct agcttgaggg aaagtccttg
    13381 ggtgggttgg gaaaatttca aatttttatt ttcttcggat caagcatttc tcatcactaa
    13441 aaatacaatt ttatataatg tagcatttat ccttttgaat ctgctgatct cagtcgtatt
    13501 tgcaatcatt atgagcgagt tgagaaataa acgactcgtt aaagtttatc aaacgatgtc
    13561 cttactacct tattttctat cttgggtcat tatcagttac tttgtttacg cttttttaag
    13621 tcctgacaaa ggaatattca atcagtggat cactggacat ggaggagaag ctgtcaattg
    13681 gtataatgaa ccgaaatatt ggccgtttat cttggtgttc attggtacat ggaaagggat
    13741 tggttataac agcattattt actttgcatc tgttatggga atcgatccga cttattatga
    13801 agctgctatg gttgatggag ctagcaaatg gcagcagatc aaacatgtga cgataccaca
    13861 acttattcca ctaatgacga ttttaacgat tttagccgta ggaaacattt tccgagctga
    13921 ttttggcctg ttttataaca ttcctaggaa ttccggtgca ttatatgatg tgactcaagt
    13981 tttggatacg tatatctaca atggcctgac atccacagga gattttggta tgacggctgc
    14041 tgcaggactt taccaatcag ttgtcggctt tgtcttgttg atgatcacaa atacgatcgc
    14101 ccgacgtttt gatagcgatt ctgcattatt ctaaggagga aaaaaatgaa aaaaaagaaa
    14161 gtggagagag tccaagtccg ctctttcaat aagacggcta attttttctc taatataatg
    14221 attgcactct ttgctatttc ctgtattttg ccatttatat ttgttatcgc catctctttt
    14281 accgatgagt ccatattgtc gactcacggg tacagttttt ggccagaaaa gttcagtata
    14341 tttggttata cgtacttgtt cgaccagatg caggataaaa ttttccaagc gcttttcgtc
    14401 actgtacttg ttactgtttt aggtacactg atcaatagca cggctacttc tttatatgct
    14461 tatgcgattt cacggtcaaa ctttccattc cgtcgttttt ttaccgtttt ttgtttgatt
    14521 acgatgttgt tctcaccagg gatggtggcc aattatcttg ttatgacaaa tcttcttcag
    14581 ttaaaagata cgatttgggc attgatcttg ccaatggctg tcagtccctt caatattatt
    14641 gtgatgcgca cattctttaa acgttcggtc tctgattcga ttattgaatc ggcacggatc
    14701 gatggagcta gcgaactgcg aatatttgtt cagatcgttt taccgttagc tgttccaggt
    14761 attgcgacaa tcagtttatt tgccgcattg ggttactgga atgactggtt caatgcttta
    14821 ctatacatcc aagatgataa gctagttcca ctacagtatc ttttgatgaa aatccaaagt
    14881 aatattcaat atctgacaca aaattcagga gcaggaagcc aattgacagg cggattagcc
    14941 tcagttccag gagaatctgc cagaatggcg atcgtagtca tctcgacgtt gcctattgcg
    15001 atcagctatc catttttcca gaagcatttt gtcaaaggtc taacaatcgg cggagtaaaa
    15061 gaataaagaa acaaaaatat aaatcataaa attaggagga agaaaaatga agttatggaa
    15121 gaaactagcc tttacaggtg tttcagcgtt gttgttggga acattagcag catgcggagg
    15181 ttctggttct aaagaccagg cagaagctag caattcggac actttgcaga tgtatcaaat
    15241 cggagataaa ccagataatt tcgatcaatt gatggaagta gcaaacaaac gaatcgaaaa
    15301 agagatcggt gtaaaagtca atatcaatta cattggctgg ggcgattacg aaaagaaaat
    15361 gaacgtcatc atttcttccg gggaaaatta tgatatcgcc tttgcgaaca actatgtttc
    15421 caatgcccaa aaaggagcct ttgctgattt gactgaatta gcgcctaagt acgctgaaaa
    15481 agcttataat gatttagatg aagcatatat taaaggaaat ctggtcaatg gaaaattata
    15541 tgctttccca gtcaatggaa atgtctttgc tcaacaagta cttactttta acaaagcttt
    15601 actagataaa tacgatcttt caattgatgg aatccaatct tacgctgatg cagaaaaagt
    15661 cttgaaggaa ttccatgaaa aagaaccaaa cacggcagct tttgccattg gacaaggctt
    15721 caaagtccaa gggaactttg attatccttt agggaatacg ttaccatttg ctattgatct
    15781 ggatggagat gattcgaaaa tcatcaacca atacgataat gaaacgtata tcggactgtt
    15841 acgtacaatg catagctggt acaaacaagg actcattcca agtgacgctg caacgagcaa
    15901 taaggattat ccactagaag gaaatacttg gctaatgcgt ggagaaacac aaggaccgta
    15961 tgattatggc gatacaattt tgacaaatgc agcaaaacaa gaacttgtct caaaagcaat
    16021 tactgttcca ctaaaatcta cagctcaagc acaaatggca aattttgtcg tatcaaatac
    16081 ttcaaaaaat aaagaaaaat cagtagaact tctagggctg cttaacagtg atccagaatt
    16141 attgaatggg cttgtttggg ggatcgaggg agaagcatgg gaaaaagtcg atggttcaga
    16201 tgataaaatc aaattgctag atggttatca gccaaataca catatgtctg cttggaatac
    16261 aggaaacaac aagattctat atacacaaga gtctattacg gatgacatga ttgccaaacg
    16321 tgatcaatcg attgctgatg cagaaacttc accgatttta ggattcagct tcaacactga
    16381 cagtgtcaaa acagaattaa gtaatatttc taatgtcatg aatcaatatt tagatggatt
    16441 gaatacaggg actgttgatc cagatgaaac attaccgaaa ttgaaagacg ctttggacaa
    16501 ggctggctat gataaggtat tgaaagaaat gcaaaaacaa tatgatgagt tccgacaaga
    16561 ataataatga ataaagacaa aggggttgtg acaaaagacg tgtcacaacc tcttgttccg
    16621 aataaacggt gttcaaaagc cagtttctcg gtattaagct aaatatatgt aaaaatgtgg
    16681 aaagccatat tcacaaaatt tttcttacta ctcgaaacta agcggctatt tcacaaactc
    16741 ttggtaaacg gtgttcaatc agctgaccct cggtattcgc tcacaaaacg acaaaatatg
    16801 aggaactatt tttccgtttg tttctctaat aatcaggtca aggtgctgat tgcccaacct
    16861 ttttttgtat aatgagaaag tataaactta atgtttggag gagaagatat gttagggaag
    16921 gttttggaag agttatttat ccggatctgg gtcattataa aactaacctt gtatttctgg
    16981 atatatacat ttgccggcgg gatcatcttt ggattaggtg cggcatggaa aacagtcaat
    17041 gaactatttt atttgtacgg attcgagtat aaagaaatca caataaaaag aggctggaat
    17101 atatataaaa gaaatttttt aagaggcaat ctgctattta gtttattttt atctggtact
    17161 gctttattga gttacaattt atatttatct gttcaaatca aagggctcat ttttttagct
    17221 attgatttta ttttactttt tgccttgctc tgcctatttg ctacttatca atacagtatg
    17281 attttagata gtgaatatac gatctctgtt cctaatctgc taaagctaag ttttatttcg
    17341 gttttttcca gcttttcgtc ttttctaaaa ataattattg gtagcggtat aattttaggc
    17401 gtgacttggc aattcaaagg attgatcctg tttggtgtca ttggtctttt gacggtttgg
    17461 aatggtacga tgacaacaca ttggcgtgaa gaattagata aacagttgga aagttatgaa
    17521 taagtttcgg attctatttt caaaaggaac cttactaaat cgtctgttgc ggaaatacgc
    17581 ggttatcatg atcggtgtaa cgatgactgc taccgttatt tttagtatcc atacttggga
    17641 acaaaatcaa aaacaggcag aaaacatgac aagtgatgcc gttcaaagca caagcagaat
    17701 gctgaatgat aaaacaacct tgagtaggat catcaaaaac cagcttgtag ggaattccga
    17761 aaagatcgaa aatgtgacga cctacttaac aaaacccata gatcagtatc tgatgtatgt
    17821 atacgaacag caaaacagta ccgatgaatt agtttctttc ccaaatcaaa tcaaagatct
    17881 ctacgcaaat tatgaagaac taagtgcgat atatatcgtg ttgaatcaac taccggagta
    17941 ttatgaatct tctagagaaa acaaaggtgg ggaaataaaa aaggggacac caaaattact
    18001 agacgccttt tatatcaagt tgcctatcac acaaggagga gctgagtcag gaagtatttt
    18061 tattggtttt caaaagaaag aactagatat gattttagaa aatctaacgt cattcaatgg
    18121 actctcttta tacatgattt ctggaacgac aaatcgacta tacacattcc atgataataa
    18181 aatagctaaa gaaacgtttg aaagacaaga aatgatcatc acagagagtc tgaagaaaaa
    18241 ttcacaattg ccgattgacg atctggaaaa aaacaatttt gttcaacacc aagaactgtc
    18301 tgatgattat cgtatattag ctgtactaga taaaaaaagt gtaaaaatcg aaacgggaaa
    18361 aaatcttgcc ccgctgatca ttggtatcat tattttagac aatatactgc ttatctttct
    18421 ttataaaaca ttcaaacgat attcacagca agtatctatc gtcatgcagg ccatggatca
    18481 aacagcagca gggaatttag agacgcggat cgacataaca aacacggaat atgaactgaa
    18541 ggaactttca atcggtatca acgaaatgtt ggatagcatc aatcagtttg tagaagacat
    18601 ctacaaatta gaaatcaaac agcaagacgc acatatgcgg gcgcttcaag cacagatcaa
    18661 tccacacttt ttatataata cattagaata tatccgaatg tatgcaatca gcgaaggaag
    18721 tgaagaatta gcagatgttg tgtatgcgtt ttccgctttg cttcgaaaca atacgaatca
    18781 agagaaaacg atcactttaa aagaagaact ggacttttgc gaaaaatatg tctatttgta
    18841 tcaaatgcgt tatcctaatc gagtagccta tcattttatg atcgatcctg atttggaaaa
    18901 gatcgaagta cctaaatttg tgatccagcc attagttgaa aattatttta aacacggtat
    18961 tgattttact cgattcgata atgcgctaag tgtcaaagtc ttgcaggaag gcaaacgggt
    19021 aaggatcatc atcaaagata atggaaaagg gatgactgaa aaacggctaa aacagattga
    19081 agaaaaactg tctcatccta aagtggaact tcacggttct atcggtctgc aaaacgtgaa
    19141 tgaacgttta cgtgccagct tcggcagcag ttattatatg tcgcttgaga ataatgagac
    19201 aggtggactg accgtttcta ttgcattcaa ggagggatga gcgtgtatca agtgttattg
    19261 gtagatgatg aatacatgat tttgaatggg ttaaaaaaga taattgattg gcaaagttta
    19321 ggctttcaaa tagtagcaac agcagagaat gccaaagaag gactagctgt acttgaacag
    19381 cgacagattg atttagtagt aacggatgtg acaatgccag aaataaatgg actggaattt
    19441 attgaagcgg ctcaaaaaga acgtcataat tttgaattta tgattttatc aggataccaa
    19501 gaattcgatt atttgaaagg aggtatgcaa ttaggcgccg tgaattattt gatgaaaccc
    19561 gtgaataagt tcgaattggt tgaaagcctc aagaaaatca aaacacggtt agatcagcaa
    19621 aatgaacaaa aaaatcaaca agaaatctat caagaactgt tattcagtca atggttgaat
    19681 gaagaattgg atgaaataag tgaagaagaa ataataggac aaataagtga gaagcagcat
    19741 aggatagtat tgattcaact ggcaagaact catgatactc ttatcaatag atggttgcaa
    19801 gaacggcaac aaatctttta ctatcaacga aattacggag accgtgtatt gatcacgttg
    19861 ttgttggagg cagatgaagt tgatggcttc tgttgttttg ttcaagaaaa ctttcctgat
    19921 caggaatggc tgatcagtat cggggaagag acagattctt tggacaaaat ccctgaaaca
    19981 ttccaacaag cgaaagacaa tctacagttg catcaatttt atggagataa agacgagcat
    20041 gttttttacg cagtacaagc agaaacaaaa gatcaaacca tcgatttttc aagtttcaga
    20101 cgcgtgctgc aaaataaaca attggaagtc gctcaaaaaa tgatcactga tttttttgaa
    20161 cagtttcagt tagcagccat gatgccggaa gatatacgat attccagttt tttactgttt
    20221 atggagattc aacgggaatt gattgatctg gaagatgagg aatatttaca aggaatcgaa
    20281 aaaatccatc aggcaaaaac ggtgcaagaa cttcagcagc tacttctgtc attcatcaaa
    20341 aagcatcaga gacagaaaaa gtacagtgac aatgtggaaa aagtaatcgt aatcctgcac
    20401 cagcattatc aagaaccact tacactcaaa gaagtgtcag aaaacctgca tttaaatgtc
    20461 atgtatctag gacagctgtt caaaaaagaa acgaaaaaaa gtttttcagc ttatttgaac
    20521 catttacgta tggaaaaagc gaaacaactg cttttgcaca gtaatcaaaa catcaatgag
    20581 atagcaagtg agattggcta caacaacacc acgtatttct ctaaattatt caagaaaatc
    20641 gtcggcagat cccctaaaga gtaccgagaa aacagtggag aatcataaaa gaaaaagcca
    20701 atgtaatgaa ataacttata aaaaattgtc tagaaatcta attttgggct gttcttatta
    20761 cttgaggcaa ggcagctttt tcatgacctc tcgataaacg g
//
LOCUS       DACGMI010000053        20594 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.055, whole genome shotgun sequence.
ACCESSION   DACGMI010000053 DACGMI010000000
VERSION     DACGMI010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.055"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            95..1870
                     /locus_tag="IXT46_002172"
     CDS             95..1870
                     /locus_tag="IXT46_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAQ4948073.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(1936..3522)
                     /locus_tag="IXT46_002173"
     CDS             complement(1936..3522)
                     /locus_tag="IXT46_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAQ4948074.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            3773..3997
                     /locus_tag="IXT46_002174"
     CDS             3773..3997
                     /locus_tag="IXT46_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAQ4948075.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            4139..5890
                     /locus_tag="IXT46_002175"
     CDS             4139..5890
                     /locus_tag="IXT46_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4948076.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            5890..7674
                     /locus_tag="IXT46_002176"
     CDS             5890..7674
                     /locus_tag="IXT46_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4948077.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFLAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            8000..8851
                     /locus_tag="IXT46_002177"
     CDS             8000..8851
                     /locus_tag="IXT46_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4948078.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     EKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            8905..10656
                     /locus_tag="IXT46_002178"
     CDS             8905..10656
                     /locus_tag="IXT46_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4948079.1"
                     /translation="MAKPSTNKLEGIEMGKYQELARKIVENVGGKENINGLTHCITRL
                     RFKLKNEEKANDEILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAV
                     STEKMRPFDMLIDGISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNI
                     GDSVFQFMPVIIGLTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSG
                     TIFEAPIYQTVFGIPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFF
                     TVLITMPLGFLLVGPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWA
                     IVPMGLMQFSVNGWQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVG
                     ITEPAIYGFTLPRKKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGD
                     LTDVINVLIGIAIAMVVSFTLTFFFWKDEAGETDDIQKKSGKEIVKTPIQGQIAPLNA
                     AKDAAFAQGTLGRGILIYPEKGEVRAPFDGTVMTLFPTKQAIGMVSETGLELLIHVGL
                     DTVQLEGKYFESLVQQG"
     gene            10660..10830
                     /locus_tag="IXT46_002179"
     CDS             10660..10830
                     /locus_tag="IXT46_002179"
                     /inference="COORDINATES: protein motif:HMM:NF012578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948080.1"
                     /translation="MKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGET
                     VGPDDALITALT"
     gene            complement(10870..11772)
                     /locus_tag="IXT46_002180"
     CDS             complement(10870..11772)
                     /locus_tag="IXT46_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4948081.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            12003..13406
                     /locus_tag="IXT46_002181"
     CDS             12003..13406
                     /locus_tag="IXT46_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAQ4948082.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEENGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            13406..14839
                     /gene="ascB"
                     /locus_tag="IXT46_002182"
     CDS             13406..14839
                     /gene="ascB"
                     /locus_tag="IXT46_002182"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAQ4948083.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDAFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYASRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            14984..15910
                     /gene="trxB"
                     /locus_tag="IXT46_002183"
     CDS             14984..15910
                     /gene="trxB"
                     /locus_tag="IXT46_002183"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAQ4948084.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            16124..17851
                     /locus_tag="IXT46_002184"
     CDS             16124..17851
                     /locus_tag="IXT46_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAQ4948085.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            17923..18216
                     /locus_tag="IXT46_002185"
     CDS             17923..18216
                     /locus_tag="IXT46_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAQ4948086.1"
                     /translation="MPDTQKSKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAITQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(18308..19168)
                     /locus_tag="IXT46_002186"
     CDS             complement(18308..19168)
                     /locus_tag="IXT46_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAQ4948087.1"
                     /translation="MTSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            19260..19688
                     /locus_tag="IXT46_002187"
     CDS             19260..19688
                     /locus_tag="IXT46_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4948088.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGKIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            19850..20026
                     /locus_tag="IXT46_002188"
     CDS             19850..20026
                     /locus_tag="IXT46_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAQ4948089.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            20053..20499
                     /locus_tag="IXT46_002189"
     CDS             20053..20499
                     /locus_tag="IXT46_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAQ4948090.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         6700 a         3577 c         4410 g         5907 t
ORIGIN      
        1 tttaaattta gacaaacaag gtatactggt agaaaagtaa aaaaacgaaa agtttcacaa
       61 gcaagtggca aaacgtgatt ggaaggacga aaagatgctg aacactttaa aacccttgat
      121 caaccaacta aaaaagaaac atacatactt tattcttggc atagccctat tatttacaat
      181 tattcgtttg tatttatata gtaaagcaat ctatggaaca gacatgtcgg caacctatga
      241 tgaccagctg ctgattcgct atgctcaaaa tattttggac ggtaaatggc taggggagta
      301 tacgactaca acactttcca aaggaatctc ctacagctta tttttagtac ttgcacataa
      361 actgcatctt tcttatgcag ttttgttcgg catgttcagt atttttgcca gtatattggt
      421 tgcactcgcg tttaaaccga ttgtgaagaa caagtatctt cttttaagta tctattttta
      481 ttttttgttt tctccgatta gttttacaca tgaatattcc actcgaacat atcgtaatgc
      541 cctcgtgatt ccggctgttg agatcattat cgcttgttta ttagctattt attaccgcaa
      601 atacggttct agcagaaaat tgctgccatg gtttttaggg ctttctgtcg cttttccttt
      661 cttttggttc attcgcgaag attctatctg gcttcttcct tttactgtag tagctttggg
      721 tatcagtttc gtccagatct tgctagggca agacttttct ttcaaagaag taaagaagtt
      781 aaaaaaacga ctctttcttc tctcgaaacg ggaatggctg aaactttcat tgtttttact
      841 tcctatagtt ggcttttcca tcgtctatca atggatcgaa tataaaaatg agacaacata
      901 cggtattgca accatcaatg accgttccag tggagaattt ggacgtttga tgaaacaact
      961 gatccgaata gatgatgaaa cgaacttgaa taaagaaaac agtgagatat gggtctcaca
     1021 tgctgcacta aataaagcat tagccgcatc tcctacattc catactgttt ctacccgtat
     1081 tgacgaatta tatacgactc acgcgtggac tcaaggtgga aaagtaaaag aattacccgg
     1141 agatatcatc ttttgggcat tgcgagatgt ggtaagcgaa tctggttatt accaaaacaa
     1201 tgcaaaagaa accaatgatt tttggaaaaa agtcaaccaa gaattagaag aagcctatca
     1261 caagggaaca atcaaaaaga aaaaagagtt ctatctgatg ggatcaggag atggaaagac
     1321 gatgagtgat ctgccaatcg tattcgattt ccttcaatca ggatacgctt atgcatggcg
     1381 atataaagat ttccatcaag gaggaaatta tagtttcgga acgcaagaac aagtcaaaca
     1441 ggctcaagaa ttattaaacc ttccgctaat ggagaattgg atcgatagta atgaaccgag
     1501 aacacctaat ttccaattaa caaaatcagc aaaagtcgcg aatgtcatca taaaaattta
     1561 ccaagttctg gctattcccg tgctgattgc ttcaatagca gggatattac ttatgatact
     1621 aggaaccgta tttgcaaaag ctgatcgtgc ctattatagt tcctctttga ttgtggtcac
     1681 cggattaata ctgacacaat tggtttttct tttcggtgtc tcatggtttt gttcttatgc
     1741 gccagaaaaa aaggactatt ttttaagtgt ctacactggt gcaggcgtgc cattaacgca
     1801 attcatcgta gtaacaagca tgctagtttt cagtaaatta aatctgaaaa aagctttatc
     1861 ttctaaataa aaagaccctt ggtagctaga tttttaacct aactatcaag ggtctttgtg
     1921 tggaaaaatc agtttttatt cgatttcttc taccgtttcc tgcaaaagct gttcatattt
     1981 tttgtttcct ttatataaat caccaatcgt ccatgccaac aggagaagga caagaacaat
     2041 gattacataa gcgatgtgat cagccaatgc tagttgagcg gaagtggctt gctcgccgaa
     2101 gaaactttcg atctgtcctg gtaatcctcg taagttcaag taagttagac taatcacaga
     2161 gaaccagcca agaagtttta cgatgaatga atttttaaat cggctaccca tctccgcttg
     2221 gctgttggtc atcatcagta aaggaatcat cgaaaacggc aacgcaaaag ccaagaacac
     2281 ctgggattca ttcattaagt tattcaaagc ggcatgttct tcgatcgttc cttttgtact
     2341 tgtaaacaaa acacaaatca atacaggaat cacagaaagc aatcgtgtga ccagtcttct
     2401 tagccaaatc gggatacgca tatggatgaa tccttccatg atgacttgac cggtcaacgt
     2461 accagtaata gtagagttct ggccagaagc aagaagtgct acagcaaata aagtggacaa
     2521 gataccagat tttgctacag caatcaaaat accattgctc atagctgatg gatcagataa
     2581 agcttcatac agaccaaaaa aggaaggatc ttggacagaa ccggttttga agacagcgac
     2641 acccatgatc aatagcagtg cattgactag aaaagccatt gacaactgga tattagaatc
     2701 ccaagtagaa aaacgtacag cttgtgctac atcttcttcg ttttggtgat cgatcttccg
     2761 agtttgtgaa actgctgaat gaagatataa gttatgcggc atgactgttg caccaataat
     2821 ccctaaagct ccagtcagcg gagtttcgcc gccgatgacc ggtgagtctg agaatgtatg
     2881 actgttaggg ataaagccag caaataaact gtgccaatct gggttagaca agccaacttg
     2941 atagacaaaa acgaataaaa tgacgaaaat taagcagaca accagtgctt cgatcttacg
     3001 aaacccgact tttgtcagta gtaagagaac gaaaacatct aatacagtaa taaagacggc
     3061 aatcaccaat ggaatatcaa aaagtaagta gagggcgatt gctgcaccaa tgacttctgc
     3121 aatatctgtt gccataatgg ctaattcagt caagatccat aaaatgacac ctaatgtctt
     3181 acttgtgcgt gctcggattg cctgtgccaa atccatttgg ctcacgattc ctaattttgc
     3241 tgccatatac tgtaaaagca tagcaatcag actagacatc aaaataactg acatcaataa
     3301 atattggaaa ttttgtcctc cggtgatcga agtagaccag ttacccgggt ccatataccc
     3361 aactgctact aacgcaccag gtccagagta agcaagaagt gttttaaaaa aacttttccc
     3421 ctttggtaca tcaactgttc catttacttc agctaaagat aaaccatttg tatgttcaat
     3481 aagtcgatgc ttatgaaatt gtttattgga ttgattattc aagaaaaaac cacctttcct
     3541 atttatctac gattacattc tacacctcaa aaagaaaaaa ttaaagaaaa agattcggta
     3601 cgcctaattt tttttcatgg cgcgtcttgc tagatgacga aagaaatttt gttctcctct
     3661 aaaaaaacca ctattttttg catgaaacta aagaatacgc ctttcttttt tcaataaact
     3721 ttagtaaaat aagtcattga gagcaattcg gaaatagaaa ggagagattt atatgttatc
     3781 aacaggtatt gtcgtactta ttgctattat tgctttgcta atcggcgcag taggtggctt
     3841 tttcctagcg cgtaaatata tgaaagacta tttagaaaaa aatcctcccg ttaatgagga
     3901 catgttgcga tcaatgatga tgtcaatggg gcaaaaacca tctgagaaga aaattcgcca
     3961 gatgatgcag caaatgaaga accaagggaa aaaataggtt ctgacccaac gactttttac
     4021 gggctgattt tttcagtccg ttttttattt cgtaatttgt tagactattc agattattca
     4081 gcaaaaaaga caagcacaga caatcctagg ctcttgataa agacaaagga ggagtaaaat
     4141 gtcgattttt agaaaattag gctggttttt tcgtcaggaa aagaaacatt atttaattgg
     4201 ggttttctcg ctattcgcag tggccttggt acagttagtt cctccaaaag tgattgggat
     4261 catcattgat gagatcgccg ataaaaattt atcaataaag atcattttcg ggtggatctt
     4321 cctattgatt atcgctgctt ttttacaata tctttttcgt tatatctggc ggacgaatat
     4381 ttggggaagt gcagctcgat tggagaaaga acttcggcag cagttattca aacattttac
     4441 agaaatggac aatctctttt accaaaaata tcggactggg gatttgatgg ctcacgcaac
     4501 gaatgatttg aatgcgatcc agaatgtagc aggagctggt atcttgacct ttgcagattc
     4561 agtgattacg ggcggaacaa cgatcattgc gatgattttg tttattgatt ggcgcttaac
     4621 actgattgcg ctgattcctc tgcctttgct ggccgtcact tcacgagtgc tggggtcaaa
     4681 actccatgat gcttttcgtg attcgcaaga agctttttct agtatcaatg ataagacaca
     4741 agaaagtatc actgggatca aagtcattaa aacatttgga caagaaaaag aagatctagc
     4801 ggattttgaa gaaaagattg aagatgcaat tattaaaaac aaacgagtca attttttaga
     4861 ctccttattt gatccattca ttaccttgat tatcggtctg tcttatgttg caacaattat
     4921 tttaggtgga aagtatgtct tggaaggcac gatctcgatc gggcagatgg tctcatttat
     4981 tagttatatc ggtatgcttg tttggccgat gtttgcgatt ggtcgattgt tcaacgtatt
     5041 ggaaagagga aatgcttctt atgatcgcgt caatgaactt ttgcatgaaa agacgcatat
     5101 cgtggaacaa ctgggtgcag tgcagacccc ggcaaaaggc gagctgaatg tagctatttc
     5161 ctcttttaat tatccgaaag aagaatcacc agcattagaa caaatcaagt ttgcgatcca
     5221 agaaggagaa acattaggta ttgttgggaa aactggtgcg ggaaaaacga cgatcatcaa
     5281 attactgatg cgtgaatacg atgattatca agggaaaatc caatttggcg gacgttcgat
     5341 caaagaatat tcattgaatg ctttattagg atcaatcggc tatgtgcctc aggatcactt
     5401 cttgttttcg atgaccattc gagataatat ccgtttttct aatccaaaac tttcagaaga
     5461 agaagtagag catgcggctt ctttagcatt tatcaacaat gaaatcaagg aattaccaaa
     5521 aggttatgat accttagttg gagaacgtgg agtctcttta tctggcggac agaaacaaag
     5581 gatttcgatt gctcgagcat tgatcaaaaa tcctgaatta ttaatattag atgatgcact
     5641 ctctgcagta gatgccaaaa cagaagaagc tatcttgcat aatttaaaag aaataagaaa
     5701 agagaaaaca actatcattg cagctcaccg tttaagtagc gtgatgcatg caaaagaaat
     5761 cattgttgtc gatcaaggga aaatcattga acgaggaacc catcatgagc tgcttgcact
     5821 aggcggctgg tatgaacaaa tgtgggagaa acagcaatta gaagcgaaga tagaaggagg
     5881 cgaggcctga tggatgaaaa ttatcaatcg gaatggacaa aatcgattcc acttaaagaa
     5941 cagaaaaaga tcatcaaacg actgatgaag ttcgccaaac cttttagaag aacgttcatc
     6001 gttgctatct tatttgcgtt tgctttgtct gtgatcaatg tcctattgcc aaggatcatc
     6061 caaactttta tggatgatca tctggctaaa cagtcggcta cgacacaagt tattttgttt
     6121 tttgctggta tgtacttatt tggagtcata gtaaaaagta tcatttggtt tttccaatgg
     6181 tatttgtatt ccatggcctc attgaagacc tatcagtata ttagggtaaa attatttgaa
     6241 aagctgcata cactaggtat gcgttatttt gatcagacac cggcaggatc aaccgtttct
     6301 cgagtgacga atgacacaga aacgctattt gaattttggt acgtcttttt gatggtattg
     6361 actgggatct ttgcagtcgt ttcttcattc cttgccatgt ttcaaatcaa tggagaaatt
     6421 gccttgtgga ctttggtgtt tttgccgatt ttaggaatcg tcatctggta ttaccagaaa
     6481 ttcagttctc gtatttaccg aaatatgcgg gaaaaattaa gtcagctgaa cacgaaattg
     6541 aatgaatcga tttccggcat gcgtattatc cagcagtttc gccaagaagc tcgtttagct
     6601 aaagaatttg aacaagtgaa caatgagtat ttagacacgc gttatgcgat gatcaaaacg
     6661 aattcgattc tgttaagtcc gatcatcaat tttctatatg cattggcgat tgcgttggtg
     6721 ttgactttgt ttgggatcga tgcgttgcat tctcccgtag aagttggact gatctatgca
     6781 tttacgacct atgtccaggg attttttaat ccaatgtctc aaatgatgga ctttttgagc
     6841 atcttcacag atgggatggt tgctggtagt cgtatcttga agattatgga tacggaagaa
     6901 tatgcaccac aacaaaaccc tggagcagat caaatgatta cttcaggtaa gattgagttt
     6961 cgcaatgtaa gcttttctta tgatggagag cacaatgtat taaacaatat ctcttttgtt
     7021 gctaatccgg gagagaccgt tgcattagtg ggacacaccg gaagcggaaa aagctcgatc
     7081 atcaacgtat tgatgcggtt ttacgaattt tatgaaggtc agatattgat tgatgatcat
     7141 gacattcgag aatatccaat ggaagagtta cgtaagaaaa tggggctggt cttgcaagat
     7201 gctttcttgt tttatgggga tatcgcagga aatattcgga tgatgaatcc agctatcaca
     7261 gacgaacaga tacgccatgc ggctgagttt gttcaagcaa acaaattcat cgatgaatta
     7321 ccaaaaggat atcactcaaa agtgatcgaa catggtgcca gctattctag tggacaacga
     7381 cagctgatca cttttgcgcg aacaatcgtg actgatccta aaattctagt attggatgaa
     7441 gcaacagcaa atatcgatac tgaaacagaa ggattgatcc aagaaggatt ggcaaaaatg
     7501 cgtcaaggac ggacaacgat tgcgattgcc catcggctgt caacgattcg agatgcagaa
     7561 ttgattttag ttttagacaa aggtcatata gtagaacgcg ggaatcatga aacacttcta
     7621 gcgcaaaatg gtttgtatgc agatatgtac aaactgcaaa gcagtggtat ataaaagatg
     7681 ttgtgacagt agaattttga cctaagcact agagtgaaaa taaaacatag cttctcatat
     7741 ttttcatctg tgagagttag tgtcgtagtc accagattta aaaaaagatt cgacagctag
     7801 tcagaagtgc ctaatagcca ctaagaaagc gttgacaaaa gcatttgctt tcgataatat
     7861 aaagaaaacg atacaacttg gatagtgatt gcctgatgca agctaaacct gatgagtctc
     7921 ccatggtttc atggacggct ttttgggttt ttctttttgt tttggataca gccctataca
     7981 tcatggaaag gagcaaaaca tgctgattga gaaagtactg aataacaacg tcgtaataac
     8041 cagggatgaa agaaatcagg aaatgatcgt gatgggaaaa ggtttggcat tcaaaaagaa
     8101 agtgggtgac ccgatttttg actcatgcat cgaaaaaaaa tttcagttga caaatgacgg
     8161 gctttcacaa cagttccaag aattggcaca agcgattcct cttgagtact tagaaatttc
     8221 ttgtgaaatc attgaatata caaaagaggc tctacaagtc cagttgaatg attctgtgta
     8281 tattgcattg acggatcatt tgtatacggc tatcgaacgt cacaaaatgg gaatatttgt
     8341 accaaatgta ttgctgtatg atatcaaaca actatttcct aaagagtatg ccatcgggaa
     8401 aaaaacagtg aagaaaatct cggataaata ccacatcaag ttatcagaag atgaagccgg
     8461 atttatcgca ttgcatttag tcaatgcaca aggcattcaa agccagcaag acaataccta
     8521 cctgtttact ataacaatac aggatattct aaatatcgtc cgctattact ataagattac
     8581 atttgatgaa gattcagtcc atttttttcg attcgtcaca cacttacgtt tttttctgac
     8641 acgcgtccta gatggagaaa aatcagaagt gggagaagtt tctgaggaat tgtttcaggt
     8701 tattcaaaaa aaatataagg atacgtttgg ttgcgttgag aaaatagcag actttttagc
     8761 cgagacgttc aactaccaga tgtccacgga cgaaaaaatg tatttaacga tccatactgc
     8821 gcgtttagtg catgagaatc gttgtaaata aaaaaaggag gataaattaa caagaacgta
     8881 tgaaataagg gtagtgacat tcagttggct aaaccttcca ctaataaatt ggagggaata
     8941 gaaatgggaa aataccaaga attagcgaga aaaatcgtag aaaatgtcgg cgggaaggaa
     9001 aatatcaatg gtttgacaca ttgtatcaca aggcttcgtt tcaaattaaa aaacgaagaa
     9061 aaagcaaatg atgagatctt gaaaaatatg gacggtattg taacggtaat gcgagcggga
     9121 gggcagtatc aagttgtcat tgggaatcat gtgccagtcg tgtttgaaga ggttataaaa
     9181 gcaggaaacc ttacttttga tgaggctgtt tcaacagaaa aaatgagacc gtttgatatg
     9241 cttattgatg gaatatcggg ctgtttccag ccattccttg ctatcctagc tgctggcggg
     9301 atgattcgtg gactgacagc attccttgtc ttcttaggcg cgtttgaccg cggttctggc
     9361 acatttgtta tgtttgataa tatcggtgat tctgtattcc aatttatgcc tgttattatc
     9421 ggtttaacag ctgcccgtaa atttaaagta aatgaattcg tagggatgtt gcttggcgca
     9481 gcattaatga atcctagctt gtcgctggaa gctttgagtg gtgcagcaga agcaccacta
     9541 acgaccatat tttctggcac tatttttgaa gcacctattt atcaaacagt attcggcatt
     9601 ccctggattg cgcgtaacta cgcttcttct gtcattccca ttatctttat tgtgttgtta
     9661 gctagccaaa ttcagaaacc aattaaaaag ttagtacctg agatgatcgc gaatttcttc
     9721 gttccattct tcaccgttct tattacaatg cctttaggtt ttttactcgt tggaccagta
     9781 ttcacattcg caactgatat tttaatggct ggatttgaaa cacttttagc actttcgcca
     9841 gttatttatg gagcaatcgt aggcttcttc tggcaaattc tggtgatgtt tggtctccat
     9901 tgggcaatcg taccaatggg attgatgcaa ttttctgtga atggttggca aaatattatg
     9961 acacctgttg cagtagtgtc ttttggacaa actgcagcac ttaccgcact ctactttaag
    10021 cttagaaatc caaaagacaa agcaattgca ataccagcca ttgtttctgg tattgtgggg
    10081 attacagagc cagctattta tgggtttaca ttaccacgta aaaaaatatt tatttttacc
    10141 tgtgtcggtg gtgcgttagg gggcgcgtat agtgggttaa tgaatttaac ttcttggaat
    10201 caaggtggac taggcatctt tacaattccc aactatatta gaccagatgg tgatttaaca
    10261 gatgtgatta atgtattgat tgggatcgcc attgcgatgg tggtatcctt tacgctgact
    10321 tttttctttt ggaaggatga agcaggtgaa acagatgata tacagaaaaa atcaggtaaa
    10381 gaaattgtaa aaacaccgat acaaggacaa atcgctccac taaatgcagc aaaggatgca
    10441 gcttttgcac aaggaacact aggtcgagga atcttgatct accctgaaaa aggagaagta
    10501 cgtgcccctt ttgacggaac agtcatgacc ctgttcccga cgaaacaggc aattggaatg
    10561 gtttctgaaa cagggctgga attgctgatt catgtcggat tggatactgt gcagttggaa
    10621 gggaaatatt ttgaaagctt agtgcagcaa ggataaagag tgaaacaagg cgatctgttg
    10681 ctacgcttcg acaaaaagaa aatcgaaaag gaaggataca gtttagaaac acctgtgatc
    10741 gtcaccaatt acacggatta tttggatatt ttggaaaacc aaggggagac ggtcgggcca
    10801 gacgatgcac ttatcaccgc actgacctga acggttaggt gaagaatgga ctaggcttaa
    10861 ctattctttt tattccactt ctttattttc aaaattgaaa ggctctttca tgatggctga
    10921 gctgataggg cgtttatcga atttttgacc gacagaaatt agatggacta aattctgttg
    10981 ataattttct gcaaaaacac aactatataa cacgtctaga agataacaaa ttgatgtatt
    11041 gatcgtaaaa ttaccaattt ttgaatacag tcgctcgcgt gtcgtaagtc gcaaagcggc
    11101 tgtactcatt gcagatagcg ttgaatcacc gatactggtc aaagctaaaa ttggaacatg
    11161 attttgtttc aatatttctg cggtacgaag gatcacattg ttttcacccg tataagaaat
    11221 cagaatcccg cacatatcac tcgtgcaatt gtacgcttca tagaatgatt caccaaaagt
    11281 ggtgacaatc gtgacatcca ttttgatgcg cttcattttc agcatgaaat cttgagaaat
    11341 caaagtattc gagttactgg cgaaaatcac gatttttttt gcttgaagca ttagttgttt
    11401 ggctttttgc agttggtcat gatgaatgag agaaagtgta tcatgaatcg tcatctgttc
    11461 taaagaagcc attttatttg cgatcgtcat aataccgtct gtggtggaaa aaggaagatt
    11521 cgcatctacg tcttgaaaat tcccttcaag ataggctgtt tcagctaaaa aagcattacg
    11581 aaaactgacc cagccatcaa aacccatttt ttttgctaca cggatgagtg tagaggggtg
    11641 gacataacat cgctcagcaa tcgcttggat ggtcatttcg ccaagtgctg gagaatcgct
    11701 taagagaaac tggatcactt cattttctga aggagaaaag gagatttctt tgattttttc
    11761 acgtaataac atgtagatac cttcttctta tttttttacg taaattataa cttttttgaa
    11821 aatgatttgt aaacggattt atactatata acttaaaata gacatttttt gacaagatat
    11881 ttacaaaaat ccactagaaa acagtaaatt ttgtaaatgt tactggaaag aaacagattt
    11941 ctattgtttg ttttgtttac aaaaaagata atgaaagtgt aaaaaagtaa aggagtgaga
    12001 acatggcaaa aggaatcaaa atcgctacga ttggtggagg cagcagttac acccccgagt
    12061 tgatggaagg atttatcaaa agatatgagg aattaccgat acgagaaatc tggctcgtag
    12121 atgtagaaga aggaaaagaa aagcttgaga tcgttagtca gatgtctcag cgtatgtggg
    12181 atgcttctcc gtatgaagtc aagatctatg caactctgga tcgggaagaa gcattgaaag
    12241 atgcggattt tgttacgact cagtttcgtg tcggtcaatt agatgcacga atcaaagacg
    12301 agcggatccc tagttattat gggatgattg ggcaagaaac aaatggtgct ggcgggatat
    12361 tcaaagcttt tcgtaccgtt ccagtcgttt tggcaatcgt tgaggacatg aagcgtttat
    12421 gtccaaatgc ttggctgatc aatttcgcga acccaagtgg gatggtgaca gaagcagtta
    12481 tcagatatgg caaatgggat aaagtgattg gattatgcaa tgtgccagtg atggcgatga
    12541 tgacagaacc agcaatgctt ggcaagaaaa aagaagagct gatctacaag tttgccggtc
    12601 taaatcattt ccattggcac aaagtagcag ataataaagg aaatgaccgc acggcagaat
    12661 tgattgatcg tttatacgat gaagagaatg gattaccgaa aaatatcttt gatatcccgt
    12721 ttttcaaaga acaattaaaa caaatgaaca tgatcccttg tggctaccac cgctattact
    12781 atcgtgaaga agaaatgctg gaacatgctt tagaagaata tcaaacgatt ggtacaagag
    12841 cgcagcaagt gaaagaaaca gaagcagagc tatttgaatt atacaaagat ccagaattag
    12901 accataaacc tgaacaattg caaaaacgag gtggcgctta ttattcagac gctgcctgtg
    12961 aaacgattgc ttcaatctat ggaaataaag aaacacagat cgtggtatct acaaagaatg
    13021 atggagctgt tcctgacctg ccggcagatt gtgtagtaga agtcactgcc tatgttggcg
    13081 cacaaggagc gagaaatgta gcgtttggtt ctcttcctgc tgctgaaaga ggctggttgc
    13141 aagtaatgaa gaatatggaa ttgctgacga tcgaagcagc tgtgactggt gattatggga
    13201 cagctttaca ggcgtttacg atcaatccac ttatacgatc aggaaagaca gcaaaacgga
    13261 tcatggatga gttgtttatt gcacaccagc agtatttacc gcaattcaag gagacaatca
    13321 gccgattaaa agaagaagga atcgaagttc aagatgaact ggcaagagaa ttatcaggta
    13381 atacacatat aatggaggaa gtataatggg attcagaaaa gattttttat ggggcggtgc
    13441 tacagcagcc aatcaatgtg agggcggtta tgatgaaggt ggacgcggac tagcaaacgt
    13501 agatgttgtg ccaatcggaa aagaccgttt tcctgttatc accggaaaga aaaaaatgtt
    13561 tgaatttgat gaggatcatt tttatccagc aaaaattgca atcgatatgt atcatcgtta
    13621 taaagaagat attgctttgt ttgcagaaat ggggttcaag acttatcgaa tgtccatcgc
    13681 ctggagtcgt atttttccaa tgggggatga gaaagagccg aatgaagctg gcttgaaatt
    13741 ttatgaggat gcctttaaag aatgccaaaa gcacggaatt gagccacttg tgacgattac
    13801 gcattttgat tgtccaatgc atttgatcaa agaatatggt gcgtggcgtt ccagagaact
    13861 cgttggtttt tatgaaaatc tgtgtcgagt catcttcaat cgctataaag gacttgtcaa
    13921 atattggctg acattcaatg agatcaatat gatccttcat gcaccattca tgggcgcagg
    13981 gctgtatttt gaaaaaggag aaaatgaaga acaaatcaaa tatcaagcgg cacatcatga
    14041 gttggttgca agtgccatcg caacgaagat tgctcatgaa gtagatccgg agaacaaagt
    14101 aggctgtatg ctggcagcag gagcatatta tccatacact tgcaatcctg aagatgtttg
    14161 ggcttctaga aaatcagatc gagaaaatta tttcttcatt gatgtccagt cacgaggaga
    14221 atatcccgct tatgcattga aagaaatgga gcgaaatggc attcagatcg aaatggaacc
    14281 aggggatgcc gcattgctga aagaacatac tgttgatttt atctcttttt cttattatgc
    14341 ttcccgagtt tcgactaccg acaacgaact cttggaacag actgcaggaa atatctttgc
    14401 ttctgtcaaa aatccatatc tgcaagcaag tgaatggggg tggcaaattg atccattagg
    14461 cttgagaata acgatgaatg atatttatga tcgttatcaa aaaccattgt ttattgtaga
    14521 aaacggctta ggtgcagtcg atacgccaga tgaaaatggt tatgtggaag atgattaccg
    14581 aatcgattac ctggcagcgc atatccaggc gatgaaggat gcagtagaac tagacggagt
    14641 cgatctatta ggctatacga cttggggatg tattgattta gtatcagctg gtaccggtga
    14701 gatgaagaaa aggtacggat tcatttatgt cgatcgtgat aaccaaggaa atggcacatt
    14761 agcccgttca aagaaaaaat cattcaactg gtataaaaaa gtaattgatt caaatggaga
    14821 aaatctttcg aacgattgat caatgattta taaaagtcta ttgtttttca gcggattttt
    14881 cgagtataat aaagctattc gagaaacgca agcagaacaa tagacttttt ttcgcattgg
    14941 ctgtaaagta tgcttacttg attaagtaaa ggagaatcta catatgtatg atgtaatcgt
    15001 tattggcgca ggtcctgctg ggatgactgc tgctttatat gcttcacgtt caaacttatc
    15061 cgtattgatg atcgaacaag gtgcccctgg cggccaaatg aacaatacgg cagaaatcga
    15121 aaattatcct ggattcgatt cgatcatggg ccccgatcta gcttataaga tgtatgaaag
    15181 tgtctcaaga tttgggacag aaaatgctta tggaatcgtt caagatatca aggatcacgg
    15241 cagccataaa gaagtcatct gtgaagataa aagttacgaa ggaaaaacag tcattatcgc
    15301 aacaggatgt atccaccgta aattaggcgt acctggcgag gaagaatttg ctggacgagg
    15361 cgtttcttac tgtgcagtct gtgatggtgc gtttttccgt aacaaacgtc tagtagtcat
    15421 cgggggtggg gactcagcag tagaagaagc catctatttg acacaatttg cttctgaagt
    15481 agtgatcgtc caccgtagag atgaattacg tgcacaaaag atcatccaag accgtgcatt
    15541 tgcaaatgaa aaaatttcct ttatgtggga tacagtcgtt gacgaaatcg ttggaaacga
    15601 aatggtagtg acaggtgtga aagcacgtaa tgtcaaaacc ggcaatgaat ttgatttagc
    15661 agcagacgga gtattcatct atgttggact ggatccatta actgcacctt ttagagaagc
    15721 aggtttgacg aacgaagctg gctggattcc aacagacaac gaaatgaaaa cgaatatgcc
    15781 aggcgttttt gccatcggag atgttcgtga aaaagatttg cgacaaatca ctacagctgt
    15841 tggtgacggc ggtattgctg gacaacaagt gtataaatac ttggagtctt tagaagaaac
    15901 aacagcataa gtttaaaaag agtagaagaa cgggttcaat tgttctttta ctcttttttt
    15961 tcgcgtgaaa tttactgaat ctgatttatg cgaacacgtc caacaccttt tgataaaaga
    16021 atcctttctt gatttaagcg ttttttggtc ctcatacttt catatctaat aagtgaatgc
    16081 tatacttatt aagaaccata tttcagaaag aggtgttatt ttcatgtctt gggaacaagt
    16141 gtatgaacaa tgggtacatg aagaaaattt agaagaaaac ttaaaaaaac aattaaatga
    16201 tctgggtgaa gatcctgaaa aacttgaaga tgctttttat gcaccgttgg aattcggtac
    16261 tgcaggtatg cggggaatct taggacctgg gatcaatcga atgaacatct atacggtaag
    16321 acaagcaaca gaaggactag cacgtttcat ggatacacaa ggtgaagaaa caaaacgccg
    16381 aggtgtcgct atcgcttatg actcacgcca tcagtcacca gaatttgcaa tggaagcagc
    16441 caaaacacta gcacatcaca atatcccgtc ttatgtattc gaaagtctgc gtccaacacc
    16501 agagctttct tttgcagttc gtcatttgaa gacgtttgcg ggaatcatgg taaccgcatc
    16561 tcacaaccca gcggcttaca atggatataa agtctacgga gaagatggcg gacaaatgcc
    16621 tcctgcagac gcagatgcat tgacgaaata tgtccgtgaa gtcagcaatc cgctaaaagt
    16681 cgaagtatta tctgacgaag aagctaaaca tagcgggttg atcacgatca tcggagaaga
    16741 agtggacgct gcttatctag aagaaatcaa agcagtgacg attgatcgtg aattggttga
    16801 aacaatgggg aaagatttga aacttgtgta cacgccactt catggaacag ggaaaatgtt
    16861 gggcgaacgt gcgttgaaac aagctggatt cgaacaattc gtactagttc ccgaacaagc
    16921 tgtggcagat ccagatttca ctacggtcaa atcgccaaat ccagaagaac attcagcttt
    16981 tgaatatgct atacgacttg gagaaaaaga aggagctgac ttgctgattg caacagatcc
    17041 tgatgcagac cgtttaggcg cagcggttcg tttgccagat ggttcttatg aagtattgac
    17101 tgggaaccaa atcggagcat tgtttgctca atatattttg gaagcacatc aatcaagagg
    17161 cactttacca gaaaacgcag cggtattgaa atcaatcgtt tccagcgaat tgcctacagc
    17221 aattgcggaa cactacggtg ctaccatgtt caatgtgttg acagggttta aattcattgc
    17281 tgaaaaaatc caacaatttg aagaagacca ttcacatact tttatgtttg gattcgaaga
    17341 aagttatggt tatttagtta aaccttttgt tcgcgataaa gacgcgatcc aagcattgct
    17401 tttattagca gaagtagcag cttactataa aaaacaaggc aaaacgttgt atgacggctt
    17461 gcaaacgatt tttgaaacct atggctattt cgcagaaaaa acgatttctg tgacaatgag
    17521 cggacaagaa ggttctgcga aaatctctgc tttgatggaa aaattccgta aagaagcacc
    17581 gacagaattt gccggagcaa aagttattca aacagaagac tttaaagaat tgacgagaac
    17641 agaccgtgaa ggaaacgtag aaaaactaac aacaccgcca tccgacgtat tgaagtatac
    17701 attggaagaa aatggctgga ttgctatccg cccttcagga actgagccga aaatcaagtt
    17761 ttatattggt gtaaaaggaa gttctacaga agacgcagcc gaaaaagtag cctcttatga
    17821 agcgattatc aaaaagatga cagaagaata aaaaacttga gactgatgga aaaagtggta
    17881 aactttagaa gtcagtcttt tttcaagttg gaggtgaatg gattgccaga cacgcaaaaa
    17941 tcaaaagtag agaaagtcag tcaattattc aaaatgttga gtgatcccac tcgtcttaaa
    18001 attctgctat atctgaaaga cggggaacaa aatgtgacag caatcaccca agcagtggaa
    18061 atggagcagt ctgctgtatc gcatcaacta cgtttattaa gagaaaatca tgtcgtcaag
    18121 tctcatcgcg agggaaaagc gattttgtat agtcttgatg attctcatgt actggatatt
    18181 ttgaaccaga cactcaaaca tgtggaacat caataacgat aggtgcaaat agataaacac
    18241 tggagtgtga caacgaagaa atttcgttgt cacactccag tgttttttaa gaaaaagaca
    18301 aaaatgatca atcgcttttt tctgttgttt cagttccata ataactatga tcttctaggt
    18361 ctaaagcatt caaaataagc gaagccgttt cttcaataga taaagatgct acattgatca
    18421 ctacacatcc tagtttttca taaagatcat tcgcaaaatc gagttcagct ctaatttttt
    18481 cgatatcgga ataagcagta tcagggttta atccgtaaga gcgcatccgt tctttacgga
    18541 tattatttaa aatatctggg ttatttgtta gtcccacgat ttttttagga tcgatctccc
    18601 aaagctgttt gggaatatgt gcttgtggga tcaaaggtaa attggcaact tttaaatttt
    18661 tgttagctaa aaacaagctc aaaggcgttt tggaagttcg ggatacgcct agcaaaacga
    18721 catctgcttc taaaaaacca cgaggatctt tcccatcatc gtattttaca gcaaattcca
    18781 ttgctttgat ccgtttgaaa tagttctcat tcaataaatg gagggcacca ggttgccgaa
    18841 ttggcttgat accagttaaa cgttcaattt ctgatatcgg tggcgtcatc acatcaaaac
    18901 taaataattg atgttcttca caaaaagaac gtgttatctc gatcagttct tgattgatta
    18961 atgtatgcag gacaagtgct ttttcttcta atgcatcttg caatgcctgc cttaatgttt
    19021 tttcatctgt cacgaacgtt ctgcggaata ggttgaactc aacggtagga tactgagcca
    19081 tagtagcttg cgctagtttt gtcgcagttt ctccagcaga gtcggagatg acaaaaaaag
    19141 taacgatttc tgtagaatcg gaagtcatgg ataaaacctc acttgcattt tttttatgtt
    19201 tattatacca tactctagaa tgcgtacttc gtaatcattt tgatttggag ggataagtca
    19261 tgaaaaaaca gacattgatc gaacaatcat tagaaacatt gaaaaataac ggttttaaat
    19321 atactaaaaa aagagaagca ttgttaactt atttagtgaa gcgtaaccgc tacgtatctg
    19381 ctaaagaagt ttttgactat atgaatcagg aattcaaagg ggtaagttat gatacgattt
    19441 accggaatct ccatgatttt gcagagatcg atttactgga agaaaccgat ttaaatggag
    19501 aaatgaagtt tcgttttcat tgctgtcagg ggaaaatcgg ccatcaccat cattttatct
    19561 gtacagtgtg cggaacaacg aaagaaatcc atatgtgtcc gatgaattat ttcgaagaac
    19621 agctaggtgg atgcacgatc gaagggcata gattcgagat tttcggaaga tgtgaaaatt
    19681 gtcaataagg atttaaataa aataacattt gataatttta aaaaaaagca agatttcctt
    19741 gacggtcaaa acagcattag atataatatt tacaggacag tcttgttttt tgagatatat
    19801 ttcaataaca attacggtta ctttttaagc tcggagggag ggaattaaca tgtcaaaaac
    19861 agtcgttcgc aaaaacgaat cacttgacga tgctcttcgt cgcttcaaac gttccgtgtc
    19921 aaaagcgggt actttacaag aatctcgtaa acgtgaattc tacgaaaaac caagtgtaag
    19981 acgcaagaaa aaatctgaag cagctagaaa acgcaaaaaa ttctagttct gtgatgaatt
    20041 ggagttggta gtgtgtcact actaagtaga ttaaacgatg acatgaaagc agcgatgaaa
    20101 gcgaaagata aggaatcttt acaagtcatc cgaatgatca agtcatctat acaaaacgag
    20161 cagattaaag aaggtcacga cttgacagaa gaagaagaac taacggtgtt gtctcgtgaa
    20221 atgaaacagc gacgtgattc tttgcatgag tttgaagaag caggacgtga cgatttagct
    20281 gaaaaagtaa aaagtgaaat tgtaatagtc gaaaaatata tgccggaaca actttccgac
    20341 gaagaaattc gacaacttgt tcaagaagca atcactcaaa ctggtgcttc atcaatgaaa
    20401 gaatttggca aagttatggg tgcaattatg cctaaagtca aaggaaaagc agatggaaac
    20461 caagtgaatg cgattgtgaa agaactatta caatcttaat tttatcattt aaactgcgga
    20521 cagtgattat ccgcagtttt ttgtgttcgt aaaaaaagaa ctaaaaaaca gctagaagaa
    20581 agaatcttat tctt
//
LOCUS       DACGMI010000054        20028 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.056, whole genome shotgun sequence.
ACCESSION   DACGMI010000054 DACGMI010000000
VERSION     DACGMI010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20028
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.056"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(201..515)
                     /locus_tag="IXT46_002190"
     CDS             complement(201..515)
                     /locus_tag="IXT46_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948091.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
     gene            801..1040
                     /locus_tag="IXT46_002191"
     CDS             801..1040
                     /locus_tag="IXT46_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948092.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(1402..1662)
                     /locus_tag="IXT46_002192"
     CDS             complement(1402..1662)
                     /locus_tag="IXT46_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948093.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1847..2344)
                     /locus_tag="IXT46_002193"
     CDS             complement(1847..2344)
                     /locus_tag="IXT46_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAQ4948094.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(2474..3184)
                     /gene="budA"
                     /locus_tag="IXT46_002194"
     CDS             complement(2474..3184)
                     /gene="budA"
                     /locus_tag="IXT46_002194"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAQ4948095.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(3197..4861)
                     /gene="alsS"
                     /locus_tag="IXT46_002195"
     CDS             complement(3197..4861)
                     /gene="alsS"
                     /locus_tag="IXT46_002195"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAQ4948096.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(5066..5728)
                     /locus_tag="IXT46_002196"
     CDS             complement(5066..5728)
                     /locus_tag="IXT46_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAQ4948097.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5738..6553)
                     /locus_tag="IXT46_002197"
     CDS             complement(5738..6553)
                     /locus_tag="IXT46_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4948098.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6815..7258)
                     /locus_tag="IXT46_002198"
     CDS             complement(6815..7258)
                     /locus_tag="IXT46_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HAQ4948099.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(7392..7730)
                     /locus_tag="IXT46_002199"
     CDS             complement(7392..7730)
                     /locus_tag="IXT46_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4948100.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7718..8095)
                     /locus_tag="IXT46_002200"
     CDS             complement(7718..8095)
                     /locus_tag="IXT46_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4948101.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            8319..9512
                     /locus_tag="IXT46_002201"
     CDS             8319..9512
                     /locus_tag="IXT46_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4948102.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9678..10100)
                     /locus_tag="IXT46_002202"
     CDS             complement(9678..10100)
                     /locus_tag="IXT46_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4948103.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            10690..11145
                     /locus_tag="IXT46_002203"
     CDS             10690..11145
                     /locus_tag="IXT46_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948104.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            complement(11307..12479)
                     /locus_tag="IXT46_002204"
     CDS             complement(11307..12479)
                     /locus_tag="IXT46_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4948105.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12685..14114)
                     /locus_tag="IXT46_002205"
                     /pseudo
     CDS             complement(12685..14114)
                     /locus_tag="IXT46_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            complement(14111..15613)
                     /locus_tag="IXT46_002206"
                     /pseudo
     CDS             complement(14111..15613)
                     /locus_tag="IXT46_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345213.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            complement(15610..17937)
                     /locus_tag="IXT46_002207"
     CDS             complement(15610..17937)
                     /locus_tag="IXT46_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4948106.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            complement(18780..19073)
                     /locus_tag="IXT46_002208"
     CDS             complement(18780..19073)
                     /locus_tag="IXT46_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAQ4948107.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            19575..19805
                     /locus_tag="IXT46_002209"
     CDS             19575..19805
                     /locus_tag="IXT46_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948108.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
BASE COUNT         5926 a         3863 c         3404 g         6835 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgaattata
       61 aactctagag aaattaattc atcctaacat aaaataattg ttcactcaaa agtttttcta
      121 gaacaattaa aacagcaggc ttcacattcg ctatacattt gtaagaagta ataattcctg
      181 tactaaaagg cataattgct ttaattattt tttgacttct cttcaaacac aagaagtagt
      241 tgtgtaataa ttgcagaaat aaggattcca ataatagata taaaatttga catggaaacg
      301 tctataacat taaaagaata aagtgttgaa gaaagtaaac tgattgaaat aacccctccg
      361 taaaaaatag tctgtgaata tacccacttt ttttcagaag acgtacttcg tttggttcta
      421 aaacctatcc ctgcatttct actcttatca aaaaaccaaa tatttagaag taataatatt
      481 gctattatta agataaaatt actgtaaaaa tccaaaagct atcctcctag caactattta
      541 aatacccaaa aaaattacct ctagataata tcatacctac gttttcactt ataaattttt
      601 tcataaaaaa agcgtttaga ggcataatcg ttaatacaga tggtaaccaa tgtatctggt
      661 ttgaactggg atatcaccct ctccatatat gtattactaa gactaataga tactataaaa
      721 gacttgatag ttttgcattg attttgccta atactgagca taggtgtatg ctaaacgata
      781 ctataaggag tgtgtacata atgaaaagaa ttctgtttat cagtttatca aatttattgt
      841 tacttactgc ttgtgggact tctgcatcaa agaacatacc ttcagatacg caaatttcga
      901 atagtatcga ttcaacaatt tctacaaatg agaaaaattc tccggtagaa acttccgata
      961 taaaagtttc tacctctgca aaaaacaggg taaagaaact gtcagcacgt ctcctttatt
     1021 tcaaacaaac tctgaattag cttcttcatc ttcttcagca aataatgatg atagtttcgc
     1081 gtttactcct aactaaatgc aacctttaca aatgctttac gataacaagc ctgagctaaa
     1141 tgatcctgat atcagttttg cattttttga aatgattgga tcggatgatc tttttaaaac
     1201 tactagtttg tctatccgaa aataggacag ttctggcagt ataggttttt atcgagtttc
     1261 tccaccaggc ctcgttacag agacagattc tctaggcgaa ccttttgaat aaatcaaaaa
     1321 tcatgaacaa tcactgccaa ctaaataaag tgccttcaaa agcttggtct tctcgctttt
     1381 gaaggcactt tatttaaatc tttatgaaac taaagtatgt tcatatttgt tgctatagtt
     1441 atatagatat tctgttgttt ccaactcata aacgtgagta tattttgcca ctacttttcc
     1501 gcatttttct aatatttcat tgcgatcgac gtcatgatat tcgtctacgc agatcacaac
     1561 acaattttct aatttactga ttacttctcc aatcactttt tgtttcaagc caataggttg
     1621 gcaaatatat ttttttccta aaatgatagt ttcgttattc atatttcatc catccttaat
     1681 gttttttcat tatttaaaat gataataaca ttaaaatatg attatgaaaa tcaataacac
     1741 ttgtgatttt ataaaaaaat aaaaaaaccg aaaaacagaa atgcccactg tctttccggc
     1801 tctttttatt cttgatttct cttctttttt gtttcaatag acgattttag ttattaataa
     1861 atgaaaaagc atttatatta aaatttgcta ataaaagatc tacatatttt tctagaaatg
     1921 cttgatcgat ttcatcatac cctttcgtta ctccgcaatc gatatctaaa acaccgatta
     1981 aattaccttc ttttaccatt ggcactacga tttctgattg tgcggctgaa tcgcaggaaa
     2041 tgtaatttgc atgggttttg acatcatcaa cgatcaatgt ttcttgtttt tcagctgatt
     2101 ctccacaaac tccttttccc atcttgatac gtgtgcaaga aactcgccct tggaacggtc
     2161 ctaaaatcaa ttcattacca tcgaataaat aatatcctgc aaagacagtc tcaggcaaag
     2221 tctcattcaa caatgcagat gaatttgcta aatttgctaa ccagttatct tctgcttcta
     2281 ataatccttg ttgctgtaat aataaaattt cgtatgcatc ttttttctgt ttttctgtcc
     2341 acatgataaa aaccgctcct ttttgatcta tggagaagat tatagctcag tttttttgta
     2401 aacgctaggt tttctcctca aaaaaacgag atacgtcagg ttaatcacct tgaacgcatc
     2461 tcgctgtctt tttctattct gcttgttgga tttctgctgc taaatcagca taatcaatcg
     2521 tttcgtgaac aaaagtcgga tcatcaactg gaaaatgctg tacaagggac gagatgcggc
     2581 taatctcaac ttttccttca gccacttcaa aatccattac atgtccgcca aatgtatgtg
     2641 tatcatcgat aaaatgcagg tgaaatcccg ctgcagcaac tccttggaat aattcaggcg
     2701 taaagaaccc gactaatgtt ccttggacat tgctttgttg gaattctggt tgagactctg
     2761 aaatttttgc tagtcttctg taaggttttt cttgcttcgg catgatacgg atgtgcatat
     2821 ttttgaataa tccagttatc ttcactgcca aaaataggtt ttccccggct tctcttacta
     2881 atatgtcttt tttcaattgt tctccatctg cagtttttga gacagaaaaa ctagtatctg
     2941 gcgtaaaatc tgtaattgct gcataggggg taagttcact tccatctaat tgggcaactg
     3001 agccatctga tcttccttga taagctacgc catctaaaaa gatgacttca ccatcaagcc
     3061 catgcaatgt tcccaatccc agagttcctt tttctaatat atgagcaatc gtttctgttc
     3121 catccatcaa gccagccatc aaagctccta atgtcccgtg ctggtataag attttttcag
     3181 tcatgtcgac acttccttaa tagaattgat ctggtaagat tgtttctccc aatttctcat
     3241 tatcacggta atcaatcgga atatcaataa ttacgggtcc ttctgtcgca aatccttctt
     3301 ctaaagcttt ttctaattcc tctacacttg tagctcggat tcctttagcg ccaaaagctt
     3361 ctgcatattt cacaaaatca actggaccaa agtctacacc tgacgcccgc tgatatttca
     3421 ttttttcttg gaactctacc atattgtagt gtccatcatt ccaaatcaaa tgaacgatat
     3481 tcaatttttt acgtaccgcc gtttctaaat cctgggcaga gaataaaaat cccccatcgc
     3541 cggaaactga tacgatttgt gtatttggac gcaccaatgc agcagaaatc gcccatggca
     3601 atgcaacacc aagcgtttgc ataccattac tgaataacaa atgacgaggt tcataacttc
     3661 taaagtggcg tgccatccaa atataatgac tacctacatc tacggtaaca gtcatatcat
     3721 ctgttacttt tgactgaagc gtgttaataa cttctaaagg atgcaagata cctgcttctc
     3781 cttttgattg aacaatgtcc cgctccgtta attctgcttg aagagatgct aaatattctt
     3841 ttgcatcttc tgacacttgt tgaggctcta atgaacctgt caataaatca agagtggctg
     3901 agatatcacc gatcaattct ctttcaggct gcataaaagg atcgatttca gctggcgctt
     3961 catcgatcac aatgatccgc gcatcttttt ccgcattcca gtttcttgct tcatattcga
     4021 ttggatcata gccaatagca ataactagat cacttcgttt caaaagcata tctcctggtt
     4081 ggtttctaaa taaacccaca cgaccaaaga aatgcgcttc taattcacgt gagatcactc
     4141 cagctgcttg gaatgtctct acaacaggca atgctgtctt tccaactaat tgcctgatgg
     4201 ctaacgtttc tttttcactt gatcctcgca tacctactaa tagtaccggt agttttgctt
     4261 ctctaatgcg ttcagctagg taacggatat catctgcaga agcagaacct aatttaggat
     4321 cgctcaatgg cttgatgaca ttcccttgga caggtgcatc cactacatct tgcgggatac
     4381 tgataaagct cgcgcctttt tttgaactct tagccatacg ataagcattg gcaatcactt
     4441 ctgaaattgt ttctggatct tggatttctg cactgtattt tgtgattggc tggaacagtg
     4501 ctgcattatc catgctttga tgggtcaact tcaatagatc gcttcgtttt acttgtccgg
     4561 caattgctaa aactgggtca ccttctgctg tcgctgttac caaacctgta gctaagttac
     4621 tagcaccagg accacttgtt gcgataacta ctcctggctc tcctgtaata cgtccgattg
     4681 cttgtgccat aaatgcagca ttttgttcgt gacgagtcac gattaattca ggaccttgat
     4741 cctctaattc attaaataca ccatcgattt ttgcacctgg tataccgaat acataatcaa
     4801 catgatgatt aatcaaactt tctactacag atttcgaacc ttgtttcatt ttttcgtcca
     4861 ttgaacatcg tcctttttat gctttatttt taattattag ttagaaataa tcacaaataa
     4921 ttgatacagt ttctaaacct gtttcattca aaagtatagc acgttttatt tcatttgttt
     4981 agccatatgt ttcaaaaaat gaaaaagaat gacagttttt acataaaaac tgtcattctt
     5041 aattgaaagt ttcaatttat aaagtctaca gatccatagt tctcatcaat ttacgattgt
     5101 tgaagtaaat caaaccaaat acgatagaag gacctagtag aatacaccat tggggcttta
     5161 cgaaaaagaa gagaaacaaa cttgtcaata gtaaaaaatc tagtaaactc acataccatt
     5221 ttttcaacgt atagtagaac gctatccgta gaacttgatt tggtttcgac gctggatttc
     5281 tcacctgaaa ataccagtag ttgatgctaa aggaaactga taaacaagca agtaaaacaa
     5341 acaacggaat caaccatttt ccataagaaa aacgtataaa aaagaaacaa tcaaaaatca
     5401 ttatcacact aactatccaa gcaaatagcc aataaaaaaa tccctttagc caaaattggc
     5461 gaaacgtctt tatgaacaaa cgtactggtg aaaaactttt ttcttttgct aattcttctg
     5521 tcatacctat catcacgatg caacctggac caataaaaag taaagaaaaa ataaaggaaa
     5581 agacattcct tccatctatc gacaaaagga acgcagctgc tatatacaag atattgacac
     5641 accaaaaaca aaggctactt gccaatgatt gatacaacca ataaaagaat tccatataaa
     5701 catttttgtc aaaacgctgc tctttcataa tcacctccta ttccttcatt cctgatgaag
     5761 cgatcccttc tacaaaatat ttttgcatcg ctaaaaatat aaaagcaaca ggaagaacag
     5821 aaacaactga ggcagccatg attaatgcgt actctgcatc aaatagccca ataaacattt
     5881 tcaaccctaa ctggattgtt ttattttccg tagaagacaa ataaatgaat ggccccatat
     5941 aatcgttcca tgtattaacg aatgtgatga tcgtcaaact ggcaatcgcc ggttttgtaa
     6001 gaggtaaaat gatcttgcga tagattcccc actctgataa gccatcgatc cgcgcactct
     6061 cacataaaga atctgggata ctactgtagt attgcttcaa caagaacaca ccaaaagcat
     6121 tgaacgcttg taatagcacc aacgaccaca acgtatatgt taaacccact tttctcatca
     6181 taatgaactg cgggatcata taagactgcc aagggacagc aatcgtgccg atatatgcta
     6241 aaaataaaat atcgcgccct ttaaaattta gtttagaaaa cccgtaagca gcaaaactag
     6301 aagtaaacaa ctgaatcaac gtgatcacaa cgcttaaaaa agctgtattc ttaaaaaatg
     6361 tcactaaagg aatacgagac caaataacca gataattctc taaatgccaa gttttaggga
     6421 tccattgaat cggaatcgtg aacacttcat tatttgcttt gaatgaagca gaaaccatcc
     6481 ataaaaaagg aatgatcgtc aataaagcta atacaatcag cagaatcata cccaaccatt
     6541 gaataaaggg catgtttttt gaacgaattt ttgctttttt tctttcattt cgaacacctc
     6601 caaagttata atcttcattt ctttgtaatg attacaatcc agaacaacgg ttattatagc
     6661 tgattcattt ccgttcttct tatgtttgta agcgcttatt taacaagtta tgtaaatctc
     6721 tttatttttt ttgatttaaa aatgaaaaaa tacaaaagca agactgtcat acgtctcgct
     6781 tttgtattga aatttcttcg attagagata cttattactg ttcaaaagct tctttgaaac
     6841 ggtgaatcaa ttcattgact acaggtgata aaatccgatt ctttttccag actagcatgc
     6901 agttcgtttc aatcattggg tcaagcggaa cgaatgtcac tcgctttgaa agatgactta
     6961 cagcaccttc tatgactaaa gcagcaccta cctgattctc aattagcgca aatacattga
     7021 aaatcaaatt gtacgttcct gtgatcagca actgctcctt ttttatgcct aaccagtcag
     7081 caaacattcg ctgtatttct ggacgctttg agatcaaaag aggtacattc gcaaagtctt
     7141 cttttgttat cacgtctttt tttgctaaaa cagaattttc taaaatgagc aatccccatt
     7201 tttcctttct tggtaacaaa atcgtttcgt atttctctgt atctactgga tctagcaaaa
     7261 tcgctaaatc taacaggctt ttttctagtc actccgtgat atcatcactt gttccgctgt
     7321 ggatatgaaa ttgaacgctg ggataatcac ggatcaactt ttctagtaat agtgccaatg
     7381 tattcgaatt atcagcttcc acacagccga tcgtaaatcg gccgctgaat aattgttttt
     7441 ttctgttctc gaattcttga gtggtttgat tcgttaaatc taaaatttct tctgctcggc
     7501 ttttttagaa aataacctgc ttctgtcaag atcattttgc ggttttcgcg tacaaacagt
     7561 tctgttccta gttcctcttc taactccttc agttgtcggc ttaaggttgg ttgtgtaaga
     7621 tgtagaactt ctgcggcttg agagattgtt ccttcttctg caattgtcca aaaatatttt
     7681 agtaagcgta actccatagc gatgctcctt gattttttta cttgatacat tccattttat
     7741 ttctagataa cacacgatca tatttcttga tttttccttg taaacgttcc aaacattctt
     7801 gcatttcagc aatttttttc gtcaaaagtt cactttcttc aatcaaaagc ttacgccgct
     7861 caaatacagt tgcttctcct tcgctagata ggcgaatata ttcaatcaaa gactcgatcg
     7921 ataatccggc atttcgcata cagatcgtaa agtcgaccca ttttaggtct tcttctgtat
     7981 aatcacggat tccgcctttt gtccgattaa ctggtggaat caacccgatt cgttcataat
     8041 agcgcaatgt atcggccgaa atgccctttt cttcactgac ttgtttgata ttcatctgat
     8101 cactctttct cttaatttct tgccacttta cttatgtatt ttatttattc tacaacttta
     8161 agtgtactcc aagtcaatac tcatttctat taaaactaag ctggattatc tatatcggtt
     8221 gtttgtgtat tatttcaaat aaaaaagtct tgttttttta ttcttttttg gatatacttt
     8281 taacaattta gggaaatttt aggaaaaggg gtataaaaat gacaacgtat cagcgaaagt
     8341 tattattatc gacatcggcg ggaattgctt tagagaatat ggatattatg tttttagctt
     8401 tttcattatc ttcaatgatt acttcttttc atattagtgg tacgcaagcg ggtttcattt
     8461 caacgatcac taatttgggg atgctcattg gaggtatttt ttttggcatc atagctgata
     8521 aatatggacg tgtgaaagta ttttctcaaa cggtccttct gttttcgatt gcttctttat
     8581 tgatgtattt tgcttcaaac atctacttgg tttatctctt tcgctttatc gcaggtgtag
     8641 gagcgggagg agaatacggg gcgtgtatgt ccttgatttc cgaaagtttt tcaaaaaaac
     8701 aaattggacg agcttcttcg gttgctggta ttggtgcgca ggtcggtgcg gctttggctg
     8761 cgattttagc tgctgtgatc attccaacgt ttggttggaa gatgttgtat gtcgtaggtg
     8821 tactgccggt gttgatggtc ttgttcattc gtcgcggctt gactgaacca aaggaattca
     8881 aatctgtaca atctgccgaa aagaaaacca aacttagcag actgtttgaa tcaaaacatc
     8941 ttgcttggca aacatgtggc cttagtatca tggtaactgt ccaaattgcc ggctattttg
     9001 ggttaatgaa ttggctgcct tcaattatgc aaaatcgatt agggctttcg gtttctgggt
     9061 cttcattgtg gatggtcagt actattttag gcatgtcttt ggggatgatg acttttggca
     9121 taatcatgga taaattgggg cctaaactag ccttttcttt gtttttaatt tgttcatcct
     9181 tatctgtcta tctacttgtg ttagcccata gccagtggag tttggtagca gccgctgtga
     9241 tagtcggcta ctttatcaat ggcatgtatg gtggatatgg cgcagtgatt agtagtttgt
     9301 atccaacaga aatccgcgcg acggcgaata atttcattat gaaccttgga cgagctgttg
     9361 gtggtttttc ttctatcgtc atcggtttct tgatggatca ttatagttta actgccgtaa
     9421 tcttgttttt gagcggtatt tacctagtca gtctgctggt cttgacaact cttactggtg
     9481 ttacagcatt aagggaaagc ttgcagcatt gatagttgag tctgtaaatg acaagaaaga
     9541 ggtgtggcaa aagcttgcat ctgcggtaat aagaccagcc aaatcaaaaa catgagacac
     9601 tgtttccgtt tggctggtcg tattacttga tgcagggcag ctttttcaac tgctaatttc
     9661 cttctatctg gcggctacta ttctttgacg tccgtcattt caaagtactt tactaataac
     9721 ttagcataac gaaaaactgt ggatacactc gtatattgag cgtctgcata atcttccaaa
     9781 tttttctcag gatgttgata catgaattca atcaaatgat aattatatga ttttctgtag
     9841 aaatgaagat aaataatgta gattgggaag ttctcctgct tttccataga aaagcgccga
     9901 ttattctcat tcttcaaaat gaccttatca ggatattttt ggaacaattc ttctaaatct
     9961 gttagataat tcaagataga cttacttgat accttcaatt cgttttgtag ttcttctatt
    10021 gaacaccaac gttctgtttc aagcagtaaa tgaatcattt taattttctt ttgagaaact
    10081 tttgttaaaa aagtctgcat attttctcct cctgtatcta ctttactata ctacatacaa
    10141 gaaaaaaaac ggatacaaat atcatattgt cacaccgtca atagtgcata aacctgttat
    10201 tatttctctt tttttcctaa gtattctatt gatatgaatc atttaatcgt ttattatata
    10261 aatgtcaata atctaataat aaaataacgt acatatttta ttattgcata cttaataaca
    10321 gaactatagc aaaaaatccc gtgtatcaaa acgggattag attaagtttc ctcaatcact
    10381 attcataaca caattattat aacaagtaag taaacaattg aaaaggacat ttattgaaaa
    10441 cggttgtttt ttacttaagg aggaaattta gtgaaaaaat tagttgcatt gtttttggtc
    10501 gcaggaagtt tgttgagtgg gtgtggtgct actacgtcta ctactcaaag cacaagttca
    10561 gctcaggctt ccagcagcag taccacgatc tccgaaagta cggcagattc atcgaaagaa
    10621 caagaacaaa ttgaaaagaa aaaagaagaa gagaaacaaa aagcggaaaa agctgcacta
    10681 gaaaaaaaag tgacagaagc ggaatctgct ttgtcacaag ctgaagcaaa tcctacaaaa
    10741 gaaaactatg caactgcttc agcagctatc caagcgctac ctgaaaacaa acaagagttg
    10801 acaagccgtc ttgctgcaat tgattccaca atcaaagcaa aagaagcaga agaagaacgg
    10861 aaaaagcaag aagaaattgc acgacaacaa gcagaacaag cgcaacaaga agcaatcgca
    10921 cagcaacaag cagaacaggc gcgacagcaa gcagcagctg aacaggcctc tcagcaggca
    10981 caagccgcag ctcctgagca aaataatgaa caaactgtct atgtcacacc gaccggttca
    11041 aaataccata cacataaatg tggaaatggt acgtataccc ctgccacttt aagcgaagct
    11101 caagctcgtg gtttaacccc ttgctccaaa tgttatggaa actaattcaa aagttatact
    11161 ataataataa aattcttctg aaacataaaa aaatagaagc tggcgttcca gatagtaaac
    11221 caaaaatagc agtttacacg tccatttcgt cagcttctct cttttttcat ttagtctgtt
    11281 ccctctgctt ttttggacat cttcattcat tctttctcaa tcaaatagta cacctctttt
    11341 tcttttcgca gtttatatct tccttttttc aatttcattg aaaactgttt cgaatgttta
    11401 tgttttacat ggattttaag caggagctcc tcatgttgca agcgatagtt cctgcctttt
    11461 aaatcagaaa atctcactag tccgtattca tcagaagctt tcacaaatgg aactttttct
    11521 ctagtaatat agtgtttgcc gttgagcgtt tttacagaaa agaccattcc ttcgattggt
    11581 cgtccgtttg tgttctttac ataaaaagat aaaggatagt ttcgcttagc gatggccaaa
    11641 gaatctaaat aagcgatgag tagccaaact aagccgattg atccaagtag tataccgata
    11701 aaccaaataa aaaatttcca ttttttccat tgatcaattc cttggatcgc tttttttgcc
    11761 tcttttgctt gataaggaat acgatgcccc gtcacaagca gtcgatgtgt attgaccata
    11821 taaggagtac aggtaagcaa agtcacgaga tctctgcctt tttggatacc caaagaatct
    11881 acttcatcag gtaagaccac ttggattttt tctacttgat acgccaatgt ctttccattg
    11941 atctggatga aaaactggtc tccttttttc aacttaggca aatctgtaaa taattttgct
    12001 tctgggagtc cacgatgccc agaaagaacg gcatgggtgt ttttcccgcc agtcggataa
    12061 gaactttctt ccaataatga cgttcctttt tgcaaaaata tttccgttgt ctgatcgaat
    12121 ataggtaagc tgacattgat ttttgggatt tcgatgactc caagcatatg ttccataaaa
    12181 aaggcattac taggtaaatc ttttaatgct tttgcatcaa ctgcttggtt gaaactgcct
    12241 atccctggtg atacgttttg ctctgccaac tgttggtttt tctttgtcat tttttcctgc
    12301 tgttttttta tttcctctga attcttattc gatgcttgct tttgataatg gatgatcatt
    12361 tgctgggcaa gaaaatcatt cagtgaatct tctacaaaag gataagaaaa gatcccgatc
    12421 ccaacgacta aaatgattgc catgaagatg tccagtattc ttattctgct tttattcatc
    12481 atgtccacct attttctaat atgtatatga agaggttgtg aaatcagcgc cttgacctga
    12541 gtattcgctc aacaaacggc aaaatagttc ctcctatttt gccgtttgtt gagcgaatac
    12601 caagagaccg accacttgtc acaacctttc tccccatttg aatcactatc gtttatttat
    12661 cgtatgattt ttgtttccaa tagtttaagc ttctgtttct tgatggcgtt ttttgaagta
    12721 gatcactgct cctccaacta aagcagtacc taccaagatg aatacgatga tccccatacc
    12781 accagttgaa ggcaagattc ctttaggttg gttatcgatc gttgtttcat cagaagttgt
    12841 tggatcatca tctactgtaa attcagtgta cgcagcttca ttcttaggta atgcgtagcc
    12901 ttctggtgct tttgtttctt gaaggcagta tgccccttgt ttcagccctt cgattgaaaa
    12961 tttcccttct gaatcagaaa tcaatttcac ttcttcccag tcagaacctg tgacttcatc
    13021 tgaccaagca tatgggtatt ctcctgaggc aagatttgct atttttttca ttaatttaac
    13081 agttggatct tttgctctta gaatagaaaa ttctgcatcg gctaattttt cttgcgtgtt
    13141 cacatcttgt ttgatgaagt ggaaatcacc gtagttttgg acattttcta cagtaatcgt
    13201 gttatccgta gttgtatttt cccgattgac tacaccgttt ggattcccaa gattggcttc
    13261 atctgcgcca tggatgatac cggttgtttg ttgcaatttt ccgtttttta ctataaaagt
    13321 agtttctttt tgtggattgg ttaattgata accatctggt gcttttgttt caactaaagt
    13381 ataattgccg tctattaatc cattgacact gatggatcct tcagtatcag ttgtgaatgt
    13441 caacgctgac tcagcaggat catagagagc gacaccagtg ttttcatcaa aaccggtcac
    13501 gaattgattc tctgaatttt tgatctggaa ttgcgcccct gctaacttat ctacccctga
    13561 aaagttccca gctttctgga ttttgatatt gctttctttg atgacatttt tagcatatag
    13621 gtgaatcgtg tctaaaggtt tgtcagggtc tgatgaattc gggttataaa agggtaagct
    13681 taacacgata tttggcgacg tttcgacacc gggctttggt gtttctacaa agacgtatac
    13741 agcatctttc ccatcagatt tacctggaag agtcaggtta gctaatcctt caccagaagt
    13801 cgttacactt gcgaagggtg tagcgtctgc tggaactgct gtgtctttac ttggatagta
    13861 cgtagcagtg atgtcatata cgttgaattc aacgccgttc aacggttcgc tattcggaaa
    13921 tgtcaattcc gttccgttgt ttatttgatt ttctggtgct gaagtgaatt tcaatttatg
    13981 caaattaacc gtaacatttt ctggtgtagg tgatacggcc tagaaacctc tgcagttcct
    14041 aggccgagaa cgaaaggaag cagcatgata gcagttccta aaaacgtcca tatttttgtt
    14101 ttgatgtttt tcattttatt tccctcctat tgtttccttt ttgttgtttt ttataaaacc
    14161 aagctgtccc tgttgaaagg actagcaaca accctaaaat tgagaaacct ccaagcatct
    14221 cttcgcttgt ttttggaaag cttcctccat ttttttcatt tgatggacca tttgtctgca
    14281 tctgaactgg cgtttttcca ttattcgtcg gatttgcttt tggttcgttg atgatttcca
    14341 atggtatagg atgaagcgga tcataactgc ctttttcaac ttcaaagaga atggttgatt
    14401 gactcaatat atatccttta ggcggtttaa tctccactag ttcgtaactt ccaaaagaca
    14461 atccatggac agaaaatgtt ccatctttac tggaagtaaa aatcgttgct cttgaatcat
    14521 ctttggctac ccaatgattt atcccgtttt cttgcgctaa gtattggtca ttttttttga
    14581 ctagaaattg agcatctgct agtttttgtt tcgtttgccg atccactttg acaaattgtt
    14641 tgcctcctgt ttggatggca agatgtgttt ctactgtttg attgtcagtc gtcaaacgta
    14701 catcgttatc aaatgtcgtt ttttcactgt tttctttcaa tgtcatttgg taacggatcg
    14761 ttaatttttt cccagcaaac gaactaagat cttttccaga atctgataag acaaaaccat
    14821 gttttgtttt ttgtgtgtga aatgtatgaa tcttgtctcc accaatcaaa aaatcgatcg
    14881 tttctggttc tagccataac tgaggatcag ctgtatcttt gatcgtatag gttcctatct
    14941 cgttgatgtt ctcaggaatt gttacggtga tgagataagg aactttatcc ccatctgcaa
    15001 aatctgtctg cttattctct actgtttttg ttaatgtgag tgcagcaggt attttttgtt
    15061 cgctctttgg atacaagtgg atggtcgtca atttatgatt agatgaatct gtcacaggaa
    15121 gcacaacgac aaatggtgct gatttttctt ttacttaatc tgaagtcttt atttccgcaa
    15181 atcggtaaac agcgtcacga ccttgctcat ctttgtccga tgcactaaaa gaagcaatgc
    15241 cctcttcctc gtctactgtt tttgtcacat tttctgccag tattttttca ctatcacttt
    15301 tttgtgctag ttttctttgt gcgtcttcca cactacttcc ttctgaccgc agcttgtaaa
    15361 attcatccga gacatcatat atagcgaaag taacgccgtt caaccctttt actccttgaa
    15421 agttatccgg gatatttatt ccgtcgtttt gactgatact tggcatctta tcgctttcga
    15481 acattcgatt atgcaaagta aatgtaatag gtgattctct agctgacaca gtcggagaac
    15541 ctataaaaaa gaccagtagg ataaaaaaga gaacagcaaa tatatccaca cgtacatttt
    15601 ttgttttttt catcgctgtt cacctgcttt tttcttacga tggataaaat aaaagaagcc
    15661 agaaaaaata aagatcagtc ctaaaaagac aaagggcagt agacctatcc cacctgtcga
    15721 aggaagcaag agagtcggat tgatcgtcaa cttagcggta tctgttgcga taatcgtata
    15781 attattgttt acacttcctt cgcctaaact aatcgttact atttgtgatc caatatctgt
    15841 ccggctgtta actgttaggg tataatccaa tgattcgcct aagacaacac cggtaacgtg
    15901 gagatttcca accgaaatcg agtgactttg ggcatcataa ttaaaggcag cgtcatcgac
    15961 agtaatcact gcgttagctt tatagatggt ataagttcct gatgtgttgg ctatatcagt
    16021 aaatgacaac ttgggatttg ctgctttgac tttgtctatt ccgctattcg ttagtttaat
    16081 tgtatagctg ccagcattaa ccatattttt tgctgattgt gcatctgctg tgtaatccat
    16141 actgctaagt gccacttgta ctggagtaag cgaactagtg acaccctctg ctagcttgac
    16201 atggattgac gggacacctg cttttccatc atatgtctta ctgccactga gctctaccgc
    16261 accgctgatt tgcttaatcg tatagacatc agatgtctgc acgatagtaa ataaatagtt
    16321 tgttctggca gctagtttag ctagtccgct ttttgtcaat tgccaagacg tataggttcc
    16381 aatttcagta ggcgcagtta cttcaactcc cttttcattc atcgctttga aatcagttgg
    16441 attccatgtg atttgatcaa tactgagatc attgtttaaa agggatgttg attctgtttt
    16501 atcattaaag gcatatttaa cgatcggtac aacagaaaga ccatcatagt acttactgcc
    16561 atttgcattg attgatactg ttgcatttgt cttataatat aggatgactt cagaaatctg
    16621 ttttccattt gcgtccttta cgattacatt tccatttgta tctaaactag ctaaaacact
    16681 cattgctgat tggttctttg tttctgtcgc tgaaacagct gtaaaggtat atccgttgat
    16741 agtaggcgta ttagtcgtca ggtcttgtgc agcacttccg taagtaagat tcattatttt
    16801 agaaggagca atcatctgtc caaaatagtc ttgatactta atagtgattg gtgtttgttt
    16861 gcctgtatag gtcaccgtat cgacgttact ttctagggct gtgaaagaac cgtttgtttg
    16921 tgcaaaagaa tagcccgtta ctgctgttgg agtgataacc actttgtcac ccacatggat
    16981 tccagataat gtagtcccgt acgttccgat ttttgctgct ccaccattga ctgtataaga
    17041 aaaagttcct gtccgattcg cattgacctg aaccgttgct gcttgatagg ttggaaaatt
    17101 tgaaacattt cccttaccat caacgatctg cccatttttg atcgagtacc ccgtgaatgg
    17161 aatatcattt gctaactgta taccgattga aaaagtactc atacctcctc cggcaggaag
    17221 ccctccccat gttgagggtg taaaagaata acttttatcc gcattgggtg taactgaatc
    17281 gatcgtattt ccagcggtag ccacccccat atagatactt tttgggaatg tgatagtagt
    17341 accatttact gtggagccaa taaacagatt atggatatct ggacggttat caataaaagc
    17401 gattgctttg gttacgcctt gtaacgcagt tttatccgca ctcatcgatc cgttaaccgc
    17461 aacaatgact ccatctttgg catatatcac tgtatatcca tctggtatgg tatgtccgtt
    17521 gaaattcgca gtggccgcaa cagtactaaa tgtctggctt ctacctgttt ctgaataagc
    17581 tttctcccct gctgcttttg ctgctgtgat ttctttttct gtcggatcaa tcagttgagt
    17641 cgaggatgtg gttgaggttg tctcgttgtt gctagactga ttggtgcttt ctatggactg
    17701 tatttcagaa tagggtggac tatttgtctc ctctgtcgtt tggttagcaa aatttgacgt
    17761 ttctgtataa acgtttacat aaatacttga taagctccct aagaaagtaa aaatcaagat
    17821 gatcgaaatc ataatgggat gtaagtattt tcttttagat acagctttga gtctagaaac
    17881 aaaatgtttt tgacatatac gttggatttt attttgagtt ttcttaatca ttttcatccc
    17941 tcctctcaat aaaaaatcat caaataatcc tttacacgtt attctaaatt taatttttat
    18001 tattttattg atgtatagaa agtttggggc tttttttctc tttttattct aaggttattt
    18061 tagtcttgtc ctttaataca aagattttat ttttaaataa aaaatactct ttttttacga
    18121 ttattgaaaa aaaaagataa aacttgatta attgaagtat tgcttaaatt tggaagctat
    18181 gagggaagaa taaaagagtt aggacgggat tatctactat ttttctttgt tttaaatatt
    18241 tgttatcttt gaacataaaa gagaaatgtg tcgactgcag tgttgtgtcc ctcatcacga
    18301 ataaacggtg ttcaattagc tgatcttgta ttcacttaaa aaatggtaaa gtacgagttg
    18361 ctattcccca ttttcaattt tctaacgctc aggacaaaat actgttttca caacctcatt
    18421 ggaataaaag catatatatt gtttcaagaa cgaaatcttg ttatcttttt aaagggcatc
    18481 tgtccaaaat ctaattttag gaggtacgtt ttggtattta ttcgtacaaa taaaagagaa
    18541 ttatctttat tcatgtaacg catccaattg attttttcat gtacgctcct ggaacgattt
    18601 tactgacgat tgcttattta actgcgaatc gctcattagc ttttatcata gctatccata
    18661 ttttgaataa cgttcttggc tttgtattat agatacagat gacaaaaaaa gttcaagtat
    18721 gcggtgtaga accaatatcg catacttgaa cttttttcaa tgagtataaa ttaaaacttc
    18781 taattttcaa ttcccatcat ctgatatgcc cgaccgtctg aacttctttt gaaaaagcca
    18841 aatgtgatta gataacgtct ttgttcgaca taatcgccac tagaaaatac gttcagcagt
    18901 atcgaattaa cctctgtttc tgtataagtc actccatggt caaagcgttt caagacttct
    18961 ttcaatagga tgtatttctt ttttgttgaa cttggtactt gttttacttt tccatcattc
    19021 atgaatgtgt ctaaaacttt catcttttct tgctccgtat aagtataaac catcttcttt
    19081 ctccttttga ttctaagaat actccattta tgttagaata ttctggattt tttattaaag
    19141 cggttactct taagaaagat attatcatag tgctcttttt tttactacta cttataggta
    19201 gatttattct aatccattat tctcccctac caataattaa agaaaaaact ggatcagggt
    19261 gttcaaatta catgctaaga aaaaagaacc cttgaatacc aagggttctt tctcagtctg
    19321 ataacaatga ttaacgacgg atttctttga tacgagcagc ttttccgtgt aatgcacgta
    19381 aacaaaacca ctatattcta ttatgtatct aacaccctca aaacagctat aaatcaacaa
    19441 taccgacata aaataaacac tatgttcaat ctgagatata tcaaaggtaa acgcattttt
    19501 gccccctttt tgcccctcaa atatcgcttt acaacaagaa cgtaagttcg tataatcgtt
    19561 ttgaggtgat ttttatgatg gaagaattta ttagaaaaaa tatcagtgat gaatatgcag
    19621 acttttatga tcaaagcagt aaaaaagata aattccagat ggatgtttca atcttagcta
    19681 tattagcttt ttccgaaaat aaacaacctg taactgcaaa aaaagaaaca gtattctctg
    19741 aaggcaaaat aaaaactcga tatatattag aggtagaaac taattttaaa aacagatcgg
    19801 agtaatggtt atgcttttta atgagacaca attatggttt aaatttgacc cttcgaatag
    19861 atttatcaaa gatttttata aagtatggaa ttcagaagtt ttctttttag caatcgaaga
    19921 tagcttatta attaatctct attattctaa taagaactat ttcaaaattc ctgctgcgaa
    19981 aactagaatg aagaagggtg tatacttttt gtttgatatc gtgactga
//
LOCUS       DACGMI010000055        19474 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.057, whole genome shotgun sequence.
ACCESSION   DACGMI010000055 DACGMI010000000
VERSION     DACGMI010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19474
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.057"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(461..1090)
                     /gene="udk"
                     /locus_tag="IXT46_002210"
     CDS             complement(461..1090)
                     /gene="udk"
                     /locus_tag="IXT46_002210"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAQ4948109.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1174..1869)
                     /locus_tag="IXT46_002211"
     CDS             complement(1174..1869)
                     /locus_tag="IXT46_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAQ4948110.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1882..2598)
                     /locus_tag="IXT46_002212"
     CDS             complement(1882..2598)
                     /locus_tag="IXT46_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAQ4948111.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2928..3533
                     /locus_tag="IXT46_002213"
     CDS             2928..3533
                     /locus_tag="IXT46_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAQ4948112.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3858..4181
                     /locus_tag="IXT46_002214"
     CDS             3858..4181
                     /locus_tag="IXT46_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAQ4948113.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4363..5733
                     /locus_tag="IXT46_002215"
     CDS             4363..5733
                     /locus_tag="IXT46_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAQ4948114.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5863..7164)
                     /locus_tag="IXT46_002216"
     CDS             complement(5863..7164)
                     /locus_tag="IXT46_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAQ4948115.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7394..9385)
                     /locus_tag="IXT46_002217"
     CDS             complement(7394..9385)
                     /locus_tag="IXT46_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAQ4948116.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9529..9795)
                     /locus_tag="IXT46_002218"
     CDS             complement(9529..9795)
                     /locus_tag="IXT46_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4948117.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10305..12431)
                     /gene="pnp"
                     /locus_tag="IXT46_002219"
     CDS             complement(10305..12431)
                     /gene="pnp"
                     /locus_tag="IXT46_002219"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAQ4948118.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12619..12888)
                     /gene="rpsO"
                     /locus_tag="IXT46_002220"
     CDS             complement(12619..12888)
                     /gene="rpsO"
                     /locus_tag="IXT46_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAQ4948119.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13139..13702
                     /locus_tag="IXT46_002221"
     CDS             13139..13702
                     /locus_tag="IXT46_002221"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAQ4948120.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13955..14476)
                     /locus_tag="IXT46_002222"
     CDS             complement(13955..14476)
                     /locus_tag="IXT46_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAQ4948121.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14479..15321)
                     /locus_tag="IXT46_002223"
     CDS             complement(14479..15321)
                     /locus_tag="IXT46_002223"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAQ4948122.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15314..16039)
                     /locus_tag="IXT46_002224"
     CDS             complement(15314..16039)
                     /locus_tag="IXT46_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAQ4948123.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16215..16511
                     /locus_tag="IXT46_002225"
     CDS             16215..16511
                     /locus_tag="IXT46_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948124.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17079..18671
                     /locus_tag="IXT46_002226"
     CDS             17079..18671
                     /locus_tag="IXT46_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4948125.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18684..19424
                     /locus_tag="IXT46_002227"
     CDS             18684..19424
                     /locus_tag="IXT46_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4948126.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5566 a         3999 c         3698 g         6211 t
ORIGIN      
        1 tagggggtgc gacaaaagag cttcttcaaa aaaataagtc gaaatctcac acaaattcga
       61 gaaataattt tcgtaagttt cttcttattt attgcatctg accacttctg ttacaacctc
      121 tcgttaaacg gtgttcaaaa gcttgcatct acgataataa gcccaaccca acgaaaaacg
      181 tgaggagctg ttttatttgg atgctcttat cgcttgatgc aaagacagct tttttacaac
      241 ctctacttca cggtgctcaa tcagctgacc ttcggtatta gctcaaaaaa cggtaaaata
      301 taaacagcta ttttccgttt cttcttttta atacttaggt caagatgctg ttttcacaac
      361 ctcttgttat aaataaaaaa acagttggct ggtgactgtt caaaaagcag aatccttgct
      421 tttcaaacgg tcgcagtccg ttcaactgtt tcgctgcgca ctatttatgg tttaagaaac
      481 tagctacttt tgttgtaatc aaatcaatag caacgtggtt ttctccgcct tctggaacaa
      541 tgatatccgc atagcgcttc gttggttcga taaattgatg atacatcggt ttaacaactg
      601 tcaaatattg ttcgatcacg gagtccaatg tgcgtccccg ttcttccata tcccgtttga
      661 tacgacgaat gatacgaatg tcatcatctg tatctacgta tactttgata tccatcaagt
      721 cacgcagacg ttcgtcttct aaaatcagga ttccttctag aatgatcact tcttttggtt
      781 cctgaatgat cgttgcctga cttcttgtat gcgctacata gtcatacacg ggtttttcaa
      841 tggctttata gttcagtaag tcgcctacat gctgaatcag cagatcatta tcaaaggcaa
      901 atgggtgatc gtaatttgtg ttcaatcgtt cttcaaaact caaatggctc tgatccttgt
      961 aataagaatc ttgttcaagc atcatgatgg aatggtccgg gaagttgttg aaaatcgcac
     1021 ggctgacact tgtctttccg cttccggatc cacccgtcac accaatgata attggcttgc
     1081 tttttgtcat tgactaaaac ctctttcgta tccgtttttt cattctaatc tattatagcg
     1141 aaaaaacacg aaaatgctat atttttctga aaattaatcc ttttcaattt ccaataatga
     1201 ataaagttcc tctaatgaat cgattcgata agtaggctgg atttcttcga tttctggtaa
     1261 tttatttcta ttgaaccaaa tcgtatcgat ccctgccata tttcctcctt tgatatcaga
     1321 agtcaaagaa tcaccaatga tcacagtttg ctttttatca aaattaggaa tgtgggaaaa
     1381 gacatgatca aaaaattctt tcatcggctt ttgcgctccg acagcttctg agacaaagat
     1441 atccttgaag taatcaagca ttcctgcatc tgttaatcgc cgatgttgcg tgtgcgacac
     1501 accgttcgtc acaatataaa gatcagcatg cggatggacc tttttcagga tttctagact
     1561 tcctggaaca agatcatgac cttggttcaa gtagtggcgg tagcgttttt ccatttgatc
     1621 actatctact gttttcccaa attgctggaa aagtaaccca aaacgactgc ctattatttc
     1681 ttctcgtgat agtctgcctt tttcaaactc ctgccataaa tgatgattca aagccttata
     1741 gctggtttcg atttctggtg tcaatgtgat tccttgttct gcaaacaaag cacttaaagc
     1801 attggcttca gttaattgaa aatctaacaa tgtatcatct acatcgaaca ataaagtttt
     1861 atatttcatc tttttgacct cctatttaaa ataaatactt aactttttca tctctgctaa
     1921 tgtcaacgat cgatactcgc ctactcctag ctgttcatct aattccaatg gtcccatgct
     1981 tagccgtttc aatgcggtca ctttctttcc ttgggctaag aacatctttt tgacttgatg
     2041 gaattttcct tcttggatcg tcaataaaac cgtactttgg tgcttgtctg ctttgagtat
     2101 ttttaaatca gccggcttac attgataccc atcagcgaat acgattccat tttcaaatgc
     2161 tgttacgtct gccggtgtca ccctttcgtt cacaactact tgataagtct ttgaaacctt
     2221 tttttctgga agtagcattt catatcccaa ttgtccattc gaagtgatca gcaatagtcc
     2281 tgttgtatct ctatctagtc ttcccactgg atataatggt tggaaacgat cggcacttgc
     2341 aatcagatcg attactgtcg tcttttctgg atctgataca gctgtaacag ctttttcagg
     2401 tttattgaga agataatagg actcatttgt ttctaagtgt tcacctgcta cttcgatttg
     2461 atgcagtaaa ctatctacat ttcgattttg tcgaaattcg actgtgccat ctatcatcac
     2521 ttgcttcaaa gcaaacagcc gcttcatttc cttgcgtgtc gtttctaatt tttcttctat
     2581 taatttatct aaacgcatgc tgtttccttt cttattacta ctaattaatt ataccttgaa
     2641 tattcttgct tgcaaataca tcatcatagt tattccttga cttaattaac agttcacgtt
     2701 acggttaaat agtaaagtga attggatttc tcatacacag cgtaatgacc tggtggagaa
     2761 aagttgaatc ctgactttct aaggggagat gcgcgcatct ctccttttgc gcttttttaa
     2821 gcgccctgcc ttcgatgatg tgcacgagat tagcctttag aattcactta aataaaatct
     2881 gtccgttacc aaagcagaca gtcacatttt aaggaggaat tttggttatg tcagtatcat
     2941 tagaagtaag taaaagagaa gtacgtcccc gttcattaag aaacaaactt cgtcacgaag
     3001 ggaaagttcc agctgttgtt tatgggtata aagtagaaag tacccctatc tcattcgatg
     3061 gtttgacact aagcaaattg ttgcgtgaac atggagcgaa cacagtcatc acgatggaca
     3121 tcgatggaca aaaagtcaat acattggttc acaagatcca aacgaacact tttaccaatc
     3181 atttcgaaca tgcagaattt ctatctgtaa acatgtcgga agaaacagaa gtcgaaacag
     3241 aagtcgttct tgttggcgaa tcagtgggtg ctaaatctgg tggagtgtta gctcaaaact
     3301 tgtatacagt agtcgtatct gctacaccag acaaattgcc tgaacgaatt gaagttgacg
     3361 tgacaaactt ggaattaggt gattctatta cagtagccga tcttccaaaa aacgacgatt
     3421 acaaattcgt gaccgacagt gaagagcaaa tcgctgctgt agtcgctcaa agtgaagaag
     3481 aaagcacagg tgaaggtggc gaaccagaag tgatcggttc aacagaagaa taatactgaa
     3541 acaatcaggt ggtgttagaa gcggcgggtc agcagctttt aacacgcctt ttttatttct
     3601 aatcgtttat tttcatatgg ggcttccact tttgtaaatg gctttacaaa cgaaaaatcc
     3661 taatttacca agcttttcct cgcatacttt tatcgtacct ttataaaaat ttatactttg
     3721 aaaaaaagta ttcaattatt gttgcatttt tcctgattct ttattagaat gaaccctcgt
     3781 tgaagtaagt atttctagtt tatcctagga ttaattataa aaataaaaca ttcgttgatt
     3841 cgaaggaggt taaacagatg tttgaaagtt ttgatagcag ccgcaaccgt tacgcttcag
     3901 ttggtgtcgt atcaagtttg ccagatgaat tgattgacag tatatggttt attattgacc
     3961 tagatcttaa gggagtcatt ccattagaaa atatattaac ctttgatttg atcgaaaatc
     4021 gtggaaaagt gacgatgcat ttttctcaag caggaagcaa tgtggaaatg gatattgatt
     4081 tgccgtttgc ctattcgaac caatttcctg ctcaagtata cgcctatgat gacggtacga
     4141 gagaaacgat ccttttacca agtgagatta gacaatatta aggtgataga taaacgtgga
     4201 tgtcccttat tttacagacc aggccaagtt gttgattctt tgactcaatt cttggcttct
     4261 ttttatggag tttcataaat tatcattgat ttctaattgg tattctcagg ataaacgcta
     4321 tatactacta actaaatttt aaagatataa ggagtttaaa agatgcgcga tttaacaaaa
     4381 ggaagccccg ctaaactgat tttgatgttc actgttcctt tactgatcgg aaatgttttt
     4441 cagcagttct acaatatgat cgatatgatc atcgtgggtc agacgctagg taaaaatgcg
     4501 ctggcagcgg ttggtgcaac tggaagcctg acatttttga tcattggctt tgcccaaggt
     4561 ttaacagctg gtttagccat tattaccgca caacgttacg gtgcaaaaga ttatcggggt
     4621 ctgaagaaaa gttttgctgc tagtgttgtc attagtcttg tcgtcactgt gattttaact
     4681 gtcctaagtc tcctgtttat tcgtccgatg cttcaattga tgcaaactcc tcctgaaata
     4741 cttgatcaag cacaaacatt tatttcaatt attttattag ggatctttgc atcagtcagt
     4801 ttcaatttgc tttctaatgt cattcgcgca cttggtgaca gccgcacacc actattcttt
     4861 ctgatcattg cggtcatcat caacgtcgta cttgatttga tctttattat ctattttggc
     4921 atgggtgtgg aaggtgcagc tattgctaca gtaatcgcac aagtttcttc cagcgtactg
     4981 tgtctagtgt atatcaagaa aaaaatgcct ttgttacagt tacgcaaaaa agatttcaaa
     5041 tttgaaaaag aagagtttgc tgtacaccta aatgctgctt tgccaatggc gtttcaatct
     5101 tcgatcatcg ctgttggtgc tatcgtgtta caagcagcac taaatagtct agggacagat
     5161 gtcgtagctg ctcaagccgc tgctggtcgt atcgaccaat ttgcaaatca gccgatgatg
     5221 tcatttggta ttgcaatggc aactttcact gcacaaaact atggtgcgaa agaatatggc
     5281 cgaatcttgc aaggggtacg tcaaacttta ctgatgagtg tcggatttag tctcttagca
     5341 ggtgctatcg tcattttctt cggtcatttc tttgttcaat tgtttgttag cccatcagaa
     5401 acacgtgtat ttgaattagc acaaacctac ttcaatatca atgggtctct ttactggatc
     5461 ttagcagtcc tgttcatttt acgctacaca cttcaagggc ttggacaaag caagatccct
     5521 acgatcgccg gtatgatgga attgcttatg cgttcttttg cagctatcgt tcttacagga
     5581 atgtggggat acccaggagc agcagcagct tctcctttag cttggatcgg ttctgttgcc
     5641 gtgttgcttt actcttatat gcgttcgatg aaacaattga aacacatggg tgaagaggaa
     5701 catttcacat tagaacatgc agaagcaaga tagccttgat taaaagaaat cgttgcggct
     5761 aaaaatgaaa acttttattg aaaatatctt cttcgtttac cgaaaacagg ttttttagat
     5821 aacaaaaagg ctgtgacaaa aaatgtcaca gccttttttc ttttattcta tttttctttc
     5881 cgtggactct actttgaaat aatcgatatg tgcatgctgg tattctaata ccgtgaaacg
     5941 gaatgatgca atctcaatga ttgttcctgc ttttatttct ttatatcggc tagaagcaaa
     6001 gcccgcaagt gtagtaaaat tcgtttcttc aaactctgga atctctacat gaaaataacg
     6061 ctggaaatca tctaatgtta gtttgccgga gatgatataa gagccatctg actgttccgc
     6121 tatcaatgct tcgtccaaat ctgtctcatc tcggatttcc ccgacgattt cttctaaaat
     6181 atcttcaatc gtcactaagc cgcttgtccc tccgtattca tcttttaaga tagcaatatg
     6241 ctttcccttt tttcgcatga tcgtcaataa tttttttata gggatcgttt cagttgttac
     6301 gatcggctct tcaatcaact gttctactgt cagctggtca tctttataag attgcttgat
     6361 caaatctggc aaggtgacat aacctaaaac attgtctttt gattctaaga taaccggata
     6421 gcgagtatgt ccttgttcaa tcgaagcttt tatcgcttct ttgacggttt ctgaagcttc
     6481 gaatacttgc atggacgtac ggtctacttg tatatctttt gccaaggtat catcaaattc
     6541 aaacacgttt tccaaataat gatattcttc tttggtcaac tctccttttt cataagaatt
     6601 caatgcgact aatgtcagct cttcttgaga caatgtctct tctccttcag atacgagacg
     6661 cacacctaat agcttcccta gccctgcagc tgaatgattc aatacccaaa taaaaggaaa
     6721 cattacttta taaaaataat gaagtggttt aactacgaac aagacgacct tctccgtatt
     6781 gacgatacta tagctcttag gaagcagttc gccaataacc acatcgatat acgtaactaa
     6841 aataaatccc agcgccacag agattgtact gctaatagcc gaactaaaag gtagtttacc
     6901 gatcactggt tctagtaaag ccgcgacaga tccttcaccg acccacccga tgatcaaacc
     6961 ggttagcgta attcctaatt gactagctga taaatagtta tctaaatggt gtgtaacatg
     7021 aagagctagc ttggcgttct ttacattttc cttttctagt tgttccaatc ttgatcgtct
     7081 gattttcact aaagcaaatt cacttgctac aaaaaatgaa gtaattgcaa tcatcaaaaa
     7141 taaaataatg aaattgataa ccatattctc ccgcctttct ctttttctat tgtacccttt
     7201 ttctacaaaa agattgaaaa taatgcgtat tcatatttag gaataaaaaa ggagatgcgg
     7261 catttttcag ccacatctcc ttatcacttc aaaatcattg cgttacttgt tgctaaacag
     7321 ctttttcatg acctctgata aacggtgttc aagtagctga cattcgacat tagttcaggt
     7381 caaagcgcta ctttcacaac cgctctttca accatgtttt ccgagtattt ccaatgataa
     7441 gcggaacagt ttcatgtttt acttcgctgt actctagccc aaaccatgtt tctggcgagg
     7501 tagcgatttt tttgattgcc agttttgcct gcatgatttg acgttgccat tttcctagag
     7561 ttgtcacatt ggaaactact tcatcaatca ggacaaattg gaaatcgcca acttctcgcc
     7621 ctggtgtcag agagtatctt tgtggctgtt ttggcaaacg gccttgtttc atcaaatcat
     7681 ggatgacttg gcgaacatat acgttgattt cctgttggac cctgaaacct aagaacagat
     7741 tcacttggac aataaaatca gtgtccatca tatctacttg atattctttc gtatatggct
     7801 catccgtcac ttccacatga acaaaccaat agactcgtgc tcttttaggc cgtttatcta
     7861 aaatcgaata gatgaactgt cggccaactt tatcttcagc catatcagga accaagaaga
     7921 ccacatttgt ctgatagatt ggtaaagaag tatcatcacg taattctcta agctgcggga
     7981 tataatctct caaagacaca tcctcggttg acgattcgcg aataatgttc ccttgttccc
     8041 aaataaacat cacgactaag atgatcaaac caatcagaac ggctacaaaa ccgcctcgga
     8101 agaatttgac aacacttgag ataaagaaaa cgacttctat cgcaccgaag aaaaaggtaa
     8161 ctaaatatgc aagccaacga gaatgcccat tttggataag ataaaagtaa agcagtgctg
     8221 ttgtcatcaa catcgtcaca gtgatcgata gaccgtaagc agcttccata tgatgagacg
     8281 ttcggaatgt gacaaccact agagaacagg cgatccataa aatcagattg actgctggga
     8341 tatacatttg cccgatactg ttcccaggat acatgatctt taaccgaggc agcagtttca
     8401 acttgattgc ttctgaaact agcgtaaacg aacctgtaat caatgcttgc gaagcaatga
     8461 ctgcagcgac tgttgcaaaa gcaacgccga tcacgatcca actttgaggc atcatttgga
     8521 agaatggatt caggttcttg atttgctgtg cttcagggtt ttgataaaca ttcaacaacc
     8581 acgcagcctg cccaaaataa ttgataacca aacaaatttt gacgtaaggc cagctcagac
     8641 gaatatttcg tttgccgaca tgtccaagat cggaataaag cgcctctgca cctgtcgtag
     8701 ccaggaaaat atttccaaga atgaacaagc ctaatttgtt atctgcacta aaaagcagct
     8761 ggatagcata ataaggattc agtgcacgga taactgtcca gtcttgactg aagttcatta
     8821 atcccattac gcctaaaaaa gtaaaccaag cgaacatgat tggtccgaat gcttttccga
     8881 caatatctgt accaaagcgt tggaccatga ataaaacaaa aataataact aaagtgataa
     8941 tgacgatcac gttctggtta ttaccgaacc ggtcaaaaaa ctgcggaatt cctcgcaagc
     9001 cttcaatcgc agtcgttacc gtcacagcag gggtcaatac cccatctgct agtaaggcag
     9061 ctcctccgat cattgcagga atgatcaaat atttcccacc ttttcggaca agtgtgtaga
     9121 gtgagaaaat tccaccttca ccatggttat ctgcattcaa tgcaatcacg acatatttga
     9181 ttgttgtcag tagagtcaat gtccaaaaaa tcaatgagac tgatccgata acaaaatcag
     9241 gattgattcc tgacaatccg ccattatctt caacaatcga tttcataacg taaagcggac
     9301 ttgtcccgat gtctccgtag acgactccca tcgctacaag caggccagcc attgatatct
     9361 ttttggtatt gtgcgttgtt gccacgtttt tccctcattt cttgttatat ggatatcctt
     9421 taggtaagct tgaatgatag atgatattct tatccatgac acccgctttc ctaaattgct
     9481 tctaattatc caagtaacac actgaagtgt caacttattt gaataaaatt attctttctt
     9541 tggacgttct ctgatacgtc ttgccacaaa tgaataaaga gcaaggcaaa aaattgcacc
     9601 caataatgct ggtatcaaat aaaaaccgcc gagttccggt cccagtggtc ctagtaaaaa
     9661 ttcgccgagc caactaccta aaaaaccgat aatgatattt ccagatacgc ctcccgggac
     9721 ttcctttcct aaaattgcgc cagctatcaa acctaatata ccgccgataa ataacgacca
     9781 taaaaaattc agcatctcct ttccctcctt tatccatatt tctcactttt attttacgct
     9841 ttattcagaa ggactccaaa aatatgcgcc aagaaactcc agaaaaaaag aagttgtaac
     9901 aaaagtgttc agcttatttc cgtagaagct gcttctggaa caccgtgaat cagaggttgt
     9961 gaaatcagcg gtttgacctg agtattagag aaacaaacgg aaaaatagtt cctcatattt
    10021 tgccgttttt tgagctaata tcgagggaca gctgattgaa catcgtttat tggagaggtt
    10081 gtaaaaaagc tgttctgcat caagtaataa gaacagccaa gtaaaaacag ctcctaatgt
    10141 ttttaacttg gctggactta ttaccgcaga tgcaagcttt tgaacaccgt ttattcgaaa
    10201 aaaaaggact gtgacacggc ttttgtcaca gtcccctttt ttcgaataat tattgtcccc
    10261 ctgtcacctt cacgatcaca agtacattat tcctatgaat taaattattt ttcttcattt
    10321 ttcgttgaac catcttcgtt caacattgct tttcttgaca gatttacgcg tccttgttta
    10381 tcgatttcag ttactttcac aaggatctca tcacctagtt taacaacatc ttcgacttta
    10441 ttgacacgat cgtttgctaa ttgggaaata tggacaagtc catcttttcc tttgatcaag
    10501 ttgacgaatg caccgaattt ttcgatacgg acaactttcc ctagataaac ttcaccaact
    10561 ttgacttctt tggtcaaatc ttcgatgatc ttgatagctt ttttgatcat ttctgcatca
    10621 gctgaagcaa tacttacttt tccatcttga tcgatatcga ttttcacacc agtttcatcg
    10681 atgattccgt tgatcgtatc gccgccttta ccgataacat ctttgatttt agcaggttcg
    10741 atctggatca tttcgatttt tggtgcatat tggcttaatt cttcacgtgg agcagcaatc
    10801 gttgaagtca attcttctaa gatttccata cgtgcttgtt ttgcttgagt taatgcttca
    10861 gttaggattt gttctgtgat tccttgaatc ttgatatcca tctgtaaagc agtgatacca
    10921 tcttttgtac cggcaacttt aaagtccata tcgccaagat gatcttccag cccttggata
    10981 tcagttagga tcgtatagtt ttcaccatca gaaacaagtc ccatcgcaat accggcgact
    11041 ggcgctttga ttggtacacc tgcatccatc aatgctaatg tgccagcaca gatacttgct
    11101 tgggaagaag aaccatttga ttccaatact tctgctacta aacggatcgt ataaggaaat
    11161 tcttcttctg aagggattac ttgtgctaac gcacgttcac ctaatgcgcc atgtccgatt
    11221 tcccgacgcc ctggagagcc tgcacgtcct gtagaaccaa cagaaaattg agggaaattg
    11281 tagtggtgga tgaatcgttt gctgacttcc acccctaaac catcaatgat ttggtgctct
    11341 cctagaggtg cgagtgtaca agctgataaa gcttgtgttt gtcctcgtgt gaacaaacct
    11401 gatccatgta cacgtggcaa taagctgacc tctgatgaca atggacggat ttcatccaat
    11461 ttacgcccgt caggacggat cttatcgatg gtgatcaatt cacgtacgac atctttttca
    11521 agatcttctg tgatttgttt aacttctttc aacaagtgat cttcatcttc atgacctgca
    11581 aatttctcag cataagcttc gcggatatcg atcttcacct gctcgatatt atcttcgcga
    11641 gcaagttttt cttcagtcat tactgctgct ttcattgtag cgtaagaagc atcaaagatt
    11701 tcttttttca atacttcatc aacttgcagt aaagtcactt ccattttttc tttccctact
    11761 gcttgaacga tttcttcttg gaaagcaact aactctttga tagcgtcaaa accaaacagc
    11821 aatgcaccaa gcatgtcttc ttctgaaact tctttcgcgc cgctttcaac catattgatg
    11881 gcttgtttcg ttccggcaac agtcaattcg atatctgttt gttctgcttg ttctactgtt
    11941 ggattcaaga cgtactcgcc atttacacga ccaacttcta cgcctgcgat tgggccgtca
    12001 aatgggatat ctgagattga tagtgctaaa gaagaaccta gcattgctgc catagctggc
    12061 gagcagtctg tttctacact catcacgatg ttcgttactt ggacttcatt acggaagcct
    12121 tctgcaaaca tcgggcgaat tggacggtcg atcaaacggg cagtcaatgt tgcttccgta
    12181 cttggacggc cttctcgttt gatgaaacct ccagggattt tccctgctgc atacattttt
    12241 tcttcataat tgatcgttaa tgggaaaaag tctgtatctt ttgcttcttt agaggccaca
    12301 gctgcactta agactactgt atctccataa cggactaaaa cggctccgtt tgcttgtttt
    12361 gctagctgac cgacttcgat ttgtaaggga cggccgcccc atgtcgtttt gaatacttgt
    12421 ttttctgaca taacttctcc ttttccttct cgtgaaagca agacgctact aaacaaatga
    12481 aaactgccga aagccgtctt ttgagcagct ttcatttggt tagtaggagt ccatctagct
    12541 tgatcacgga attttactta attgatatac gagtaaaaaa agtgagattc atgtgaatcc
    12601 cactcttttt gactaaaatt aacgacgcaa gcctaaacgt ttgatcaatt cgcggtaacg
    12661 ttgaacgtca gttttacgta agtaagctaa caagttacgg cggtgaccaa cttttttcat
    12721 taggccgcgg tatgaatgat ggtctttttt gtgcacgcgt gcatgttcat tcaagtggtt
    12781 gatttcttca gttaatacag cgatttgtac ttctggagaa ccagtatccc cttcatggcg
    12841 agcgtattcg ttgatgattt cattcttgcg ttcttttgaa attgccattt ctttcacctc
    12901 tttcgattat tcccctgcga ctgagtaaaa cgttggtgat tcgcttaacc aagtggcagg
    12961 tcatgtgcct agagcacaca gctatacttt acctgaaacc gggttgaaaa tcaagtagtt
    13021 aatcattaag aaaaggtagt tttcaaacaa tcttactact acttttccat ttttgtggta
    13081 aactataatg cgaaaataga cttgaaacac agtcttttaa gaaaggggta catattccat
    13141 gattacaatg gatgatatca ttcgtgaagg aaatccgacc ttacgcgaag ttgcaaaaga
    13201 agtttctctt ccattaagcg aagaagatat ctctttagga aaagagatgc ttgagttctt
    13261 aaaaaacagc caagatccaa tcaaagctga agaactacac ttacgaggcg gtgttggctt
    13321 agctgctcct caattagata tttctaaaag aatcattgct gttcacgtac caagtcctga
    13381 cccagaggca gatggacctt ctctaagtac tgttatgtat aatcctaaaa ttttgagcca
    13441 ttctgttcaa gatgcttgtt taggggaagg tgaaggctgt ttatctgttg atcgagaagt
    13501 accaggatat gttgttcgcc atgccaaaat cactgtgtct tattatgata tgaatggtga
    13561 aaaacacaag attcgtttga agaattatga atcgatcgtc gttcaacatg aaatcgacca
    13621 tatcaacggt gtgatgttct atgaccacat caacgatcaa aatccatttg cactaaaaga
    13681 aggcgtattg gtgatcgagt agagaattgg caggttcctt cgatactatg ctacaagaaa
    13741 gctttataaa aaaggggagt gctcaaaagc tgcacttccc ttttttatgt ttctccacta
    13801 atcgaaattt agatagacat ctagaaatcg caattccaaa aaattctgtg tattggatac
    13861 gcatcttttc ttattttttc ttatttcttc catatgggtg tttatctcag agatgataga
    13921 atagtttcta ggataaaaag tagcagctac gatgttatcc ttcgtagagg attcctgctt
    13981 cagctagttt ttgtttgatg tttttcagca tatgcttttc tgggtagcgg atcgtatgca
    14041 gatggatgcc gcctgttaat tcggataaca aagtagcatt acttttttga taacgtctca
    14101 taaaggaatc gatatcttgt ggcgttttga tgtgcaaagt tcctgctaac tcaccgtaaa
    14161 ggggatgttc cacaattaca tcaatgattt caccaccatt ttcaacgatt agtctcagtt
    14221 cttcttctgt ttgatctttt ccatgctgga cagcgatttt actgatgtgc ccagtattgg
    14281 tttcttctgt ttcgaggata taacctcttg ctgttgccac gatactttta cctgcagctc
    14341 gtagtaaagc aatatcgcct acaatgatct gacggctgac tccaaaagtt ttcgcaaact
    14401 tgctagcact cactggtttt tctgtatttg ccaaggtttg catgatttgt tttcgccgtg
    14461 tctctccttc gatcacactt attcctcctt cattttgttt tggtattcgc gcgagtgttt
    14521 catcaaatca acatacgtgt ctgttattgt ttccttatat cccttatttt tcagcagact
    14581 aacaacttta tccaatactt gctgctctct ttttgcatca taaactgctt ggttttcttc
    14641 ttttttcact tgtcctattt tagttaccgt atccattctt ttttctaata aagcaaccaa
    14701 ctctcgatcg atcatatcga tcttatgacg taatgtttca agagactctt ctgttagttc
    14761 ttcctctact gtcttgatga tacgagcagg atttcctgca atcactacat tgtcgggaaa
    14821 agatttggtc acaaccgaac ctgcgccgac tactacgttg tcccctagag tgacacccgg
    14881 cgtgacgata actcctccgc ctaaccaaac attattaccg attttaatgg gttttgcgta
    14941 ctccagaccg ctgttacgtt tcactggatg tagtggatgc gtcgccgtgt aaagctggac
    15001 attcggagcg aacatgcagt tatcaccgat ttcaatcgtg ctgacatcta aaaatgtaca
    15061 attgaaattt gcataaaaat tctccccaac aaatatatta tatccgtaat caaaattgat
    15121 aactggctcc atatagattt ttttccctgt acggccaaaa gtctctttca acaattggga
    15181 tcgcagttcc gctgattctg cttggttgat gatttggctt tgacttcttg caaacatacg
    15241 gtcggcaacc agctcaggat cattggcaaa ataaagctcg cctgcaatca ttttttcttt
    15301 ttcggttttg aattcagtca taatctgctc ctaattcttg tatttttttg aaaacaaccg
    15361 ctccgtcttc ttgaataaac gtataaggct ccgctaaata aacaggcgtt tgattgatta
    15421 ctaagatttt ggctgacggc tggcgaaact gtaccagatc acaaaacgga tgaacttgaa
    15481 aactcgttcc aacaatgacg atcagctctg cttggctgac ggcataagcc gcctgctcca
    15541 tgactccatc ttgaaaccct tcaccatata acacgatgtc tgggcgtatt tgtcctccgc
    15601 atgcttgatg tttgtcgctg tgaagatatt ctttccagtc taccgtttgt tgacattttc
    15661 gacaatgaca ttgatacaga ctcccatgaa aattgacgag ttgcgggctt ttagcctttg
    15721 cgtgcaaacc gtcgatgttt tgggaaacaa cccaaacatt tttttctttc gctagatgtg
    15781 ctatttccaa atgaatgata ttgggttttg cttcaggatg ataaatcttt ttgacaaatt
    15841 gatagaattt atccggttca ttcaccattg cttgatgact cagcaagtat tccggctgct
    15901 ccatcccgtg gtagattcct gacaaagatc gatagtctgg cactccagaa ggtgtggata
    15961 cccctgcacc ggtcaaaaat gtaatttgct gataagctaa tatctctttt gctgcttcgt
    16021 ctactgttaa ttgtttcatg ttttgtcacc tcactttcca ttatagccca tactcgaaca
    16081 aatttattgt tgaaaagtca gaaaaatggg aataaaaaag tgttatgggc atttgagcaa
    16141 tttatcacaa tgttcactga caaaagaatg aaaacgtgtt acaatactgc tgtataaaag
    16201 tgaggtgaat cgatatgtta ccattcttta tttattgggg cgttattctg gcttgtatcg
    16261 cctggttagc gttaagcgtt tatttctctg ttttttatct tgtacgcaaa gaaaatggaa
    16321 atctttgggc ttttgcttta ttcaacgtga ttgccgcaat tgttttagcc attacattag
    16381 ccgtatatcg aacatggggc tggggaatca cccaatactc aagtttgatt tatctaatat
    16441 tagccattta tggcgtcgtt gttcttttgc aagcgatcct aggacgtgag ccaaagaaag
    16501 cggcagctta aatgatcgag atggaactgg acacaggaaa ttttctgttc tagttctttt
    16561 tttattgtat tacatacatt tttgtgtata attatactat cgtttgcaat ggatagatga
    16621 ttcacatttt gattgttttt tcggtaaaag taaagatttc tatatttatc agtatttttt
    16681 caaaaaccag cagttataga ttgacaaagc ctctcgagta tcgtaaactt tttttgtata
    16741 aataactgaa tacgagatgc ctcaatcaat gaggtagagg tcgcgagaat cattaaccct
    16801 gtggagtgaa gcaaacatgg agaagcagga atagggagga tcgccgaaat gtgcactttt
    16861 ttgcttggag tgtatgttgg gacgcaagtt aagagcttgc ggactgtctt agcagtgatg
    16921 ctaagttgcg ctatgttttg tgagaggttt atcaccttat ggaattttag cggccttttt
    16981 atatctataa atcggtcgct ttttattttt tcagataaag ctttaccgca tttcatctag
    17041 accgctcgtg tatcatataa tcagaaaggg agaaaaaaat gaaaaaaaat atggtttcag
    17101 ttgccgtact atttgctttt gtcttctcac tattcagtgt gggatctctg gcaaatgcag
    17161 atgaaaaaac accgagcgat gagtttcgcg taggtatgga ggctgggtat gcacccttca
    17221 actggtctca acaaacagat gagaataatg ccttgccaat tcaaggccaa aatagttacg
    17281 ccggcggtta tgatgttcaa atcgctaaaa aagtagcaga tggtttaggg aaaaaattag
    17341 tcatcgtcca aacgaaatgg gatggtctgg ctcctgccct tcaatcaggc aagatcgacg
    17401 cgatcatcgc cggaatgagc cctactgctg aacgacgaaa agaaattgat tttaccgatc
    17461 cttattacga atcacaatta gtagtagtag ttcaaaaaga tagcaaatat gcaaaagcaa
    17521 aaagtttagc agatctttct ggagcaaaga tcactgctca gttaaataca ttccactata
    17581 ctgtgatcga tcagatacca gatgtgcaga aacaacaagc aatggataat ttctcagcaa
    17641 tgagaacagc tttagcttct ggaatgatcg atggttatgt cagcgaacgt ccggaaggtg
    17701 taacggcaac tagtgtgaac aaagacttgg aaatgcttga attcagcggt gcagatggct
    17761 tccagacaaa cccggaagat gttcagattt ctgttggtat gcgtaaaggc gacccggata
    17821 tccaaaaagt aaaccagatt ctttctggca tctctaacga tgaacgaacc aaaattatgg
    17881 accaagcagt caaagatcag cctgctgcaa ctgatagtga agaaaaacct ggcatcattt
    17941 ctgatttcac tacgatttgg aaacaatacg gcaatatgtt cttacgaggt gctggactta
    18001 ccttgttcat cgcattgatc gggacagttg tcggtactac acttggatta ctgattggtg
    18061 tcttccgttc ggtacctgaa tcaggaaatg cactgactcg cttcttccaa aaaatcggaa
    18121 atgcacttct ttctatctat gtcgaagtat tccgcggaac accgatgatg gtacaagcaa
    18181 tggtcatctt ctacggtctg gcactcgctt ttggcatttc attgaaccga acgattgccg
    18241 ctttgtttat tgtctctctc aatactggag cttacatgac agagatcgtt cgtgggggga
    18301 tttttgcagt agatgaaggg cagttcgaag ctgcgcaagc cattggtatg acccatggcc
    18361 aaacgatgag aaaagttgtt attccacaag ttttacggaa tatcttgcca gcaacaggaa
    18421 atgagtttgt tatcaatatc aaagatacag cagttttaag tgtaatcggc gtagctgatt
    18481 tgttcttcca aggaaactct gcttccggtg cgaatttcca attcttccaa acatttacga
    18541 tcgtcgggat catctactta gtcatgacct ttacgatcac cagaatcctg cgggcggtag
    18601 aaaagaaaat cgatggtcct tcagcttata ccaagcttga agaaatcgac aattcaaatt
    18661 tgcaggaata aggaggaaga atcatgaatg aaaaaattat tgaaatcaaa catctaagaa
    18721 aaagcttcgg tgaaaatgaa gtattgaaag atatcagcgt aacagtcaat aaaggtgaag
    18781 ttgtgacgat catcggttct tccggttctg gtaaatctac tttcttgcgc tgtatcaatt
    18841 tactggaaaa accaacaggc ggcgagatca tttataatgg agaaaatgta ttagctccta
    18901 aatataattt acctaaatat cgaacgaatc taggtatggt tttccaatcc ttcaacctgt
    18961 tcaacaatat gaatgtcttg gaaaactgta tgtctggtca aacaactgtc ctgaaacgag
    19021 ataaagaaac tgccaaaaaa gtagcaatcg aaaatctgga aaaagttggt atggatcgtt
    19081 atatcgaagc caaaccagca caattatctg gtggacagaa acagcgtgtc gcaattgctc
    19141 gggcattatc aatgaatcca gatgtattgc tattcgacga acctacttcg gcgttagacc
    19201 ctgaaatggt tggcgaagtg cttaatacga tcaaagactt agcacatact ggcttgacaa
    19261 tgcttatcgt gacgcatgag atggaatttg caaaagatgt atctgaccgt gtcattttta
    19321 tggataaagg tgtgattgca gaagaaggta caccagaaga tatctttgtc catccgaaag
    19381 aagaacgtac aaaagaattc ctttcacgta ttttaaatgc ttaggatcaa tagctgattg
    19441 ggacaaagag ctgcggtgtt taccgcagtt cttt
//
LOCUS       DACGMI010000056        19457 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.058, whole genome shotgun sequence.
ACCESSION   DACGMI010000056 DACGMI010000000
VERSION     DACGMI010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.058"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            133..3660
                     /locus_tag="IXT46_002228"
     CDS             133..3660
                     /locus_tag="IXT46_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAQ4948127.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="IXT46_002229"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="IXT46_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAQ4948128.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="IXT46_002230"
     CDS             7448..7789
                     /locus_tag="IXT46_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4948129.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="IXT46_002231"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="IXT46_002231"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAQ4948130.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIVRKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="IXT46_002232"
     CDS             9146..11566
                     /locus_tag="IXT46_002232"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAQ4948131.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="IXT46_002233"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="IXT46_002233"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAQ4948132.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="IXT46_002234"
     CDS             13000..13737
                     /locus_tag="IXT46_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4948133.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="IXT46_002235"
     CDS             13751..14566
                     /locus_tag="IXT46_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAQ4948134.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="IXT46_002236"
     CDS             14579..15226
                     /locus_tag="IXT46_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4948135.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="IXT46_002237"
     CDS             15242..15898
                     /locus_tag="IXT46_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4948136.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="IXT46_002238"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="IXT46_002238"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAQ4948137.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="IXT46_002239"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="IXT46_002239"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAQ4948138.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="IXT46_002240"
     CDS             18240..18758
                     /locus_tag="IXT46_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAQ4948139.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="IXT46_002241"
     CDS             18865..19365
                     /locus_tag="IXT46_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4948140.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
BASE COUNT         6540 a         3341 c         4178 g         5398 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg tgcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagc
//
LOCUS       DACGMI010000057        19304 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.059, whole genome shotgun sequence.
ACCESSION   DACGMI010000057 DACGMI010000000
VERSION     DACGMI010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19304
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.059"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            237..1628
                     /locus_tag="IXT46_002242"
     CDS             237..1628
                     /locus_tag="IXT46_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAQ4948141.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAEIDFSQEKIYR"
     gene            1687..2490
                     /locus_tag="IXT46_002243"
     CDS             1687..2490
                     /locus_tag="IXT46_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4948142.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGKRIVPEYNNAIRVFSKRRNPFNHMTVMFD
                     KKAILEVGNYQPLSGFEDYYLWARLLKAGYKGYNIQETLVYARTGKDMYARRGGMKYL
                     GSGLMGRYRIWKDGLGSVKDFIIVSCGHIFISLLPNQLRGKFYQTQLRK"
     gene            2523..3377
                     /locus_tag="IXT46_002244"
     CDS             2523..3377
                     /locus_tag="IXT46_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HAQ4948143.1"
                     /translation="MKKIQQITLKMSQEIVDFCLKNQLLCYFCGGGAIGTVREQGFIP
                     WDDDLDFFMPREDYEKFYQLWVNSEKSKKYPIQKASKNYNDHNSFTTIRDADTTFIKT
                     YQRDLDIVHGITIDIFPLDVAPVSKFSRKIQKLWALVYALFCSQVVPEKHGGIMATGS
                     KILLSIFRSPRTRYKIWSFAEKQMTKYNNEPTGYVTELCVGPKYMGNVYPAKDFESAV
                     WVPFEDTEMPVPVGYDNYLSQVFGDYMQLPPEKDQVSHHEAVYIDPEHPYTMYKGKYY
                     LTKGAEKK"
     gene            3374..4075
                     /locus_tag="IXT46_002245"
     CDS             3374..4075
                     /locus_tag="IXT46_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HAQ4948144.1"
                     /translation="MITAIIIAGGVGKRMGQDIPKQFITIEGKPIIIYTLESFQHHPQ
                     VDRILVVCKSGWEETMWAYIKEFNISKVKWVITGGSKGQESINNGVQFLKDYSEDDDT
                     IIIHDGIRPLVDELVLSDVIVKCKEFGNGVTSLPYNEQIFIKKTEETTEQYVDRNTLR
                     RVSTPQAYQYGKLRAAYDRAVKEDIGMTDSSYTNTMMVDLGETLYFAAGSDKNIKLTT
                     TDDLELFKAYLKMKD"
     gene            4083..5150
                     /locus_tag="IXT46_002246"
     CDS             4083..5150
                     /locus_tag="IXT46_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAQ4948145.1"
                     /translation="MMTLIKQPMYQEDLAKVINHTPKIKQLHGKSVLMIGASGMIGSF
                     LIDTLMAANEQLGIKIKVYAMGRNRQKLEKRFASYLELDTFEIVEGDVTEPLPKEIQA
                     DYLIHGASNTHPKAYATDPIGTIMTNLAGTEQVLKHAVATQPVRVLFLSTVEIYGENR
                     GDIEKFTEDYCGYIDCNTLRAGYPEGKRVSESLCQAYIAKHDLDIVIPRLCRTFGPTM
                     LLSDTKASSQFILNAVEQKDIVLKSEGNQYFSYVYVGDAVSAILHLLLEGEKGEAYNV
                     SSENFDLRLKELAQQLADISGKQVIFELPDEIEQKGFSKASTAVLENKKIKETGWKPI
                     FPLNESLVHTVELVKGEKYNV"
     gene            5143..6108
                     /locus_tag="IXT46_002247"
     CDS             5143..6108
                     /locus_tag="IXT46_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4948146.1"
                     /translation="MCEISIIVPVYKVEKYLRKCVDSILAQTFTDFEVILVDDGSPDN
                     SGKICDEYAEKDNRVRVIHKENGGLSSARNAGIDVARGKYLGFVDSDDYIDEDMYEIL
                     YENLKIHDADISSVELIPFYGDRYKKANKEKKVIILNKKEAIKSVLEGTQFYAYAWNK
                     LYRKELFKDNRYLDGKTFEDAYIIIDLLFQTEKIVVSNEEKYFYLQRNDSIMGKSFSM
                     NNFDVIEAWQYNKEKILDAFPDLHDSYYRRLCWAYFYVLDKMVLSSSYQQIPRKKTVI
                     EFLKKNRNFILTYKGFTKSRKIAIIALSFRVDWYRKLVEQKNKKN"
     gene            6153..7127
                     /locus_tag="IXT46_002248"
     CDS             6153..7127
                     /locus_tag="IXT46_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4948147.1"
                     /translation="MCRISIIVPVYNVEKYLKKCVDSILGQTFTDFELLLIDDGSTDN
                     SGSICDELAKTDNRIKVIHKENGGLSDARNIGIEVAKGDFIGFIDSDDYIDEDMYAFL
                     YNNILKYDAELSMCGIYDVHKNKEIKKLTPFSQLVTKSEAIELVLDGKLVVANAVSKL
                     YKKELFENVRYPKGKIAEDAAVILKIINQCNKIHVDTSQKYYYYHRGDSITSKKFTKK
                     DFDIIDVWNENEKWIIKNYPQMYDKVHTRVCWAYFVVLDKLVLTEEKGLYQEKKQVRE
                     YLIDNFFFIIKNKRLTFQRKISMLLLTFGIAAYKIPVKYQYKKVKAVN"
     gene            7198..8685
                     /locus_tag="IXT46_002249"
     CDS             7198..8685
                     /locus_tag="IXT46_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HAQ4948148.1"
                     /translation="MFIYILRIVIQFVGRSFFIYFLGAKYLGLNGLFTNILSFLSLAE
                     LGIGSSIIYSLYKPLAQKDESKVKALMNLYKKTYEFIGIFIGIVGVLIIPLLPLFIKN
                     STDIPHMYRYYVLFLLNSVLSYFFTYKRSLAIADQKNYLVAINDFAFLFFMNIVQVIA
                     LYFYSNFTLFLIVQILFTLFSNINISRTVDKRYSYLKEKDVVSLDKQTKDEVKKNVIG
                     NMSSKIGGVIVMGTDNILISTFVNLTAVGIYSNYSLIVTSVQNLCKQITNSITASVGN
                     FAVSNKKKDSFELFKKHFFINHSLIFFSSILLLTLMNPFISLWVGAKYMLPMSTTILI
                     VLNYSVQVYRNTSFVFIESFGLYWSQRKKPIIEAGVNLLLSLLLLIVFDMGINGVLIG
                     TIGSSLGFVIWYEAFIIYKTVFEKRFIHFFLTFWRSFIELIISAIVVFLLNEYLANGG
                     STFLQFITKTLITIVTTSILYLLLYFRREEFTFIKKILFRYILKK"
     gene            8742..9857
                     /locus_tag="IXT46_002250"
     CDS             8742..9857
                     /locus_tag="IXT46_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4948149.1"
                     /translation="MGGASIVASKIAKGLIDSGHEVFFVSYLESEKPQVESKYYDLYE
                     KKIFLFKNFSRFHKILEYRLFGGFVPSRYIKKEKEQLKKVLKKEKPDVIIFNTFIPSV
                     LFSEFLKYEFPTVKLITWMHSDPDYSLNHIAKFYKKEYRKSFERVDSIVCLSQDTKEK
                     LSLYNNHIKVIYNPLTLSGSSLISNLDKKIISFTARYDINIKGFDYLCEVAKNLPVGW
                     AIRIAGDGTEEERKELKRLIEKNGVLDKIICAGALFGDELINHYIESSIFISTSRSEG
                     LPLVLIEAMTYGLPVISFDHGGAKEILQDGNYGILIKNFDVQDMNNEIEKLSNNRLLM
                     EKYQKFSLERAKDFNEKKIIGEWQTLLNELGNEDVRN"
     gene            9854..11269
                     /locus_tag="IXT46_002251"
     CDS             9854..11269
                     /locus_tag="IXT46_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAQ4948150.1"
                     /translation="MRTSIKNFNLWKEWYLYIFFIGMIIRAINFYSLLPSTFDSIFFK
                     LIGISGVLLLGIDFIIKFNKRKVTYNILLIAYMVILVITSFVHKEYGLGENLKTIMWA
                     ILQYFLIYQFAFENSDNKRFFKRISWGFIYSWFVLVSMSMVLFFGKFGYEKYYNARHR
                     IRIGFLESRLFGTFSDINNAAIASLVVIVLILFYLYNKKVTGLNKIIFLINLPLQFIY
                     IVLSGSRSTYVVSIIIVAISSFIVVLKRNGTKKDLKNYILAIVSSIGSVLILFALFNA
                     TKILFQELLPHLKEINFFNFTERHKELMNNSQHINNTQTPDNTLVRKDVAENTDISNA
                     RITIWKSAWEIFKTSWLIGVSPKNVVSYAQSIIPDGYIAKVGIAIHNAYLNVLTSTGI
                     LGIIPFMAFLIKSFVLNVYRIIYNKCIGKDYHFVYCLVILSYALYAALNNELVYENTV
                     GTFVFWLFLGRVNSKNNSSYF"
     gene            11302..12249
                     /locus_tag="IXT46_002252"
     CDS             11302..12249
                     /locus_tag="IXT46_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAQ4948151.1"
                     /translation="MLNYLITGGAGFIGSTLANYLGKENNVVVIDDLSMGKKENLDES
                     KHITFIEGDVADKNLMEKVMKEYHFDYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(12289..13449)
                     /locus_tag="IXT46_002253"
     CDS             complement(12289..13449)
                     /locus_tag="IXT46_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAQ4948152.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KESNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            13614..14789
                     /gene="mltG"
                     /locus_tag="IXT46_002254"
     CDS             13614..14789
                     /gene="mltG"
                     /locus_tag="IXT46_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAQ4948153.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            14925..15404
                     /gene="greA"
                     /locus_tag="IXT46_002255"
     CDS             14925..15404
                     /gene="greA"
                     /locus_tag="IXT46_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAQ4948154.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            15572..16303
                     /locus_tag="IXT46_002256"
     CDS             15572..16303
                     /locus_tag="IXT46_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAQ4948155.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDIEVIRI"
     gene            16300..17367
                     /locus_tag="IXT46_002257"
     CDS             16300..17367
                     /locus_tag="IXT46_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4948156.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            17374..18006
                     /locus_tag="IXT46_002258"
     CDS             17374..18006
                     /locus_tag="IXT46_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4948157.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            18146..18811
                     /locus_tag="IXT46_002259"
     CDS             18146..18811
                     /locus_tag="IXT46_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAQ4948158.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            18839..19132
                     /locus_tag="IXT46_002260"
     CDS             18839..19132
                     /locus_tag="IXT46_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAQ4948159.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(19200..>19304)
                     /locus_tag="IXT46_002261"
     CDS             complement(19200..>19304)
                     /locus_tag="IXT46_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAQ4948160.1"
                     /translation="DFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT         6741 a         2703 c         3713 g         6147 t
ORIGIN      
        1 atatgaatat tgtaacttgt gaataaggaa ttagcaggag aatactagtt cagcataaag
       61 gaagtgatgg gacttctgag acaactttct gttatgcaga aatacacata taaacagaca
      121 ataaacgctt ttccccgttt cttttaattt cctttacaat ttggttattc actaggtttt
      181 taaactttgc tatggtaaga tgatagaggc attattttat ggttaggagt gtatatatga
      241 ataaaaatgg ggagtggaat gcggcacgca gaatattcat tattcttatg gatgtacttg
      301 tattaaatgt atcgatctat cttagttttt tgctgaaatt ccagggagaa gtaccagtga
      361 gaaacttaga aacctttcag cattcagcaa tttttatttc catcatcttt attgcgttga
      421 atattttgtt aggagcttat gtattctata accgaatgat cagtgatatt gtcttcatta
      481 ctgttattgg acaagtacta atagcattgg ggatcatggt agttactttt gctggccgat
      541 ggtttgcatt tccgcgtggc gtcattttga tctcgtttat cctaggtacg atattactta
      601 gtgtttaccg gatagtcgtt tacaaactgt acttaagagt cagtcgtgat aagaaagtcc
      661 ttatcgtggg tttggagaaa gatgtcgcac cagctatcca aaattttcaa tctaagaaaa
      721 acaataaaca taaggttgaa gcagtggcaa tcgataatta ttacgaaaat acaaaaaaat
      781 tgatcgatga tatggatatc gtctatttgg cttctaaaat cccagaagat gaaaaaatca
      841 acatttatca attagtgact aaaaaagaga agaaattatt tttaaatacg acttttgaga
      901 atctgacaat gataaatccg aatattatga attttgaaga tgaaagcatc attgaagctt
      961 ctgggttcag aatccaacca gaatacgaac tattcaagcg tctctttgat atcatcgttt
     1021 cgcttatttt actgatcctc gcctcacctt ttatgctaat cacagcgatt ttggtaaaaa
     1081 caacttcacc tggaccaatc atctataaac aagtacgtat tacgaaaaat caaaaggaat
     1141 tttcaatcta taaattccgt tccatgagtg cgacagctga agcaaaatca ggaccagtct
     1201 tggctaaaag taacgatgca cgtgtgacac cagtaggtaa atttatccgt gctgtacgtt
     1261 ttgacgaatt acctcaaatc tttaatgtat tgaaaggcga tatgtcgatt gtcggtccaa
     1321 ggccagaaag accatttttc gttgatcagt tcaatgaaga aaatccttat tattacttaa
     1381 gacacaatgt acgtgcggga attaccggat atgcacaagt atacggaaaa tatgtatcag
     1441 attataacag taaactacgt tttgatttgt tgtatatcaa aaaatattca ttactattag
     1501 atttgaagat tttacttcaa acaatcaaaa tcttatttga taagatgtca tctcaaggac
     1561 tagatgaaga tgaaaatatt agttcattag cagaaatcga cttttcacaa gagaaaattt
     1621 atcgctagat tggaaaaatt ttgagcaaag aggtaggaga gaacattgga aaataaaaat
     1681 gtaagtatgc tgctttcttt atatgataaa gaaaagccag agtatttaaa ggaagcatta
     1741 actagtattt ttgagcaaac agtaatgcca aaagaaattg tattagttta tgacggccct
     1801 ataaatgaaa aacttcaagt agttgtcact tatttccaac aaaaagatcc tcacttgttt
     1861 acagttgtaa aattagaaaa aaatcaagga ttggggattg ctttagcaat tggattagaa
     1921 catacgaaaa atcgcttagt agccagaatg gatacagatg atataatgga accccaacga
     1981 ttagaaaaac aattagagat cttccaaaaa gatccagaaa tagcgattgt tgggagtaat
     2041 attgaggaat ttactggcac gcttagcaat gttatcggaa aaagaattgt acctgaatat
     2101 aacaatgcaa ttcgtgtatt ttctaaaaga agaaatccct ttaatcatat gaccgttatg
     2161 tttgataaaa aagctatttt ggaagtggga aattaccaac cattaagtgg gtttgaagat
     2221 tattatcttt gggcaagatt attaaaggca ggttataaag gatataatat tcaagaaaca
     2281 ttagtctatg cgcgaactgg caaagatatg tatgcaagaa gaggcggaat gaaatatctt
     2341 ggttctggtc ttatgggtcg ttatcgtatc tggaaagacg gtttagggtc agtaaaagat
     2401 tttataattg tttcttgcgg acatattttt attagcttac taccaaatca attaagagga
     2461 aaattttatc aaacgcaatt aagaaaatag gaggtttttc tttgtatagc actgatccaa
     2521 aaatgaaaaa aatacaacag attacgttga aaatgtctca agagattgtt gatttttgtc
     2581 taaaaaatca acttctttgt tatttctgcg gtggtggtgc catcggtact gtgagagaac
     2641 aagggtttat tccatgggat gatgatttag atttctttat gcctagagag gattatgaaa
     2701 aattttatca actatgggtt aattcagaaa aaagtaaaaa atatcccata cagaaggctt
     2761 ctaaaaatta taatgatcat aattctttta caactatccg cgatgcagat actacattta
     2821 ttaaaactta tcaaagagat ttagatatag tccatggaat tactattgat attttcccgt
     2881 tagatgttgc ccctgtttcg aaatttagcc gtaaaattca aaaactatgg gctttagtat
     2941 atgctttatt ttgttctcaa gtcgtccctg aaaaacatgg tggaataatg gctacaggta
     3001 gtaagatact cttatctatt ttccgctcac ctcgtacgag atataagata tggtcttttg
     3061 ctgaaaaaca aatgacaaaa tataataatg aaccaacggg ctatgtgact gaactttgtg
     3121 tcggacctaa atacatggga aatgtttatc ctgcaaaaga ctttgaatct gctgtgtggg
     3181 tgccattcga agatacagag atgccagtac cagttggtta tgataattat ttaagtcaag
     3241 tttttggtga ctatatgcag cttccgcctg aaaaagatca ggtttctcat catgaagcag
     3301 tttatattga tccagaacat ccatacacaa tgtacaaagg aaaatattat ttaactaaag
     3361 gagcagaaaa aaaatgatta cagctattat tattgctggt ggtgtgggta aacgaatggg
     3421 acaagatatc ccaaaacagt tcattacaat tgaaggaaaa cctattatta tctatacttt
     3481 agaatcattt caacaccatc ctcaagttga ccggatttta gtcgtttgca aatctggttg
     3541 ggaagaaacg atgtgggcgt atatcaaaga attcaatatt agcaaagtca aatgggtcat
     3601 tacaggtgga tcaaagggac aagagtcgat caataatggt gttcagtttt tgaaagacta
     3661 ttctgaagat gatgatacga tcatcatcca tgatggaatc cgtccactag tagacgaact
     3721 ggtattgtca gatgtaatcg ttaaatgtaa agaatttggt aacggtgtaa cctctctacc
     3781 ttacaacgaa caaattttta tcaagaaaac agaagaaacg acggaacagt atgtcgatcg
     3841 taacacattg aggcgtgtct caactccaca agcttatcaa tacggaaaac tacgggcagc
     3901 atatgaccgg gcagtgaaag aagacatcgg tatgactgat tcttcttata cgaataccat
     3961 gatggtagat ttgggagaaa ctttatattt tgctgctggt tctgataaaa atatcaaatt
     4021 gacaacaaca gatgatctag aattgttcaa agcatattta aaaatgaaag actaggtgaa
     4081 agatgatgac gttgattaaa caaccaatgt accaagaaga tttggcaaaa gtaatcaatc
     4141 atacaccaaa aataaaacag ctacatggaa aatccgttct gatgattggt gcttctggaa
     4201 tgatcggctc ttttttgatt gatacgttga tggctgctaa tgaacaacta ggcatcaaaa
     4261 tcaaagttta tgcaatgggc agaaaccgtc agaagcttga aaaaaggttt gccagttatc
     4321 ttgaattaga tactttcgaa attgttgaag gtgacgtcac agaaccctta ccaaaagaaa
     4381 ttcaagctga ctatttgata cacggtgcaa gtaacacaca tcctaaggct tacgcaactg
     4441 atccaatcgg tacgatcatg actaatcttg caggtacaga gcaagtattg aaacatgcag
     4501 tagcaaccca accggttaga gtattatttt tatcaacagt agaaatctat ggcgaaaatc
     4561 gaggcgatat agaaaaattc acagaagatt actgtggata catcgattgt aatacactga
     4621 gagcaggcta ccctgaagga aaaagagtca gtgaatcatt atgccaagcc tacatcgcaa
     4681 aacacgacct cgacatcgtg attccaaggc tttgccgtac gtttggtccg acgatgcttt
     4741 tatctgatac gaaagcatcc tcacaattta ttttaaatgc agtcgaacaa aaagatattg
     4801 ttttaaaaag tgaaggaaac caatattttt cgtatgtata tgttggagat gctgtttctg
     4861 ctattcttca tttactgctt gaaggagaaa aaggagaggc gtacaacgtt tcttcagaaa
     4921 actttgattt acgactaaaa gaattagccc aacagctagc tgatatcagc ggcaaacaag
     4981 taatttttga attgccggat gagattgaac aaaaaggttt ctcaaaagct agcacagcag
     5041 tacttgaaaa taaaaaaatt aaagagacag gttggaaacc aatttttcct ttgaacgaat
     5101 cattggttca tacagtagaa ttagttaaag gtgagaaata taatgtgtga gattagtatt
     5161 attgttcctg tgtataaagt tgaaaaatat ttaagaaaat gtgtagattc gattttagcc
     5221 caaacattta ctgattttga agttatatta gtagatgatg gatctcctga caatagcggg
     5281 aaaatctgtg atgagtatgc tgaaaaagat aatcgagtac gtgtgatcca taaagaaaac
     5341 ggcggattaa gcagtgctag aaatgcgggg attgatgttg cgagaggcaa atacttaggc
     5401 tttgttgaca gtgatgatta tattgatgaa gatatgtatg aaattttgta tgagaatttg
     5461 aaaattcatg atgccgacat tagctctgtt gaattgattc ctttttatgg tgatagatat
     5521 aagaaagcta ataaagaaaa gaaagtaatt atattaaata aaaaggaagc aataaaatct
     5581 gttttagaag gaacgcaatt ttatgcatac gcatggaata aactttatcg taaggaactt
     5641 tttaaagata atcgttactt ggatggaaaa acatttgagg atgcatatat aataatagat
     5701 ctattatttc aaacagaaaa aattgttgtt tccaatgaag agaaatattt ctatcttcaa
     5761 agaaatgata gtattatggg aaaaagtttt tctatgaata atttcgatgt tatagaagca
     5821 tggcaatata acaaagagaa gattttagat gcttttccag atttgcatga ttcctattat
     5881 cgccgactat gttgggcata tttttacgtg ttggataaaa tggttttatc aagtagttat
     5941 caacaaattc cacgtaaaaa aacagtaatt gaatttttaa agaagaacag aaattttata
     6001 ttaacttata agggattcac taaatcgcgc aaaatagcta ttattgctct gagctttaga
     6061 gtagattggt ataggaaatt ggttgaacaa aaaaataaaa aaaattagaa tgtttaaatt
     6121 agtaaataaa agaaaaggaa ttgaaaacta aaatgtgcag aataagtata atagttccag
     6181 tttataatgt tgaaaaatat ttaaaaaagt gtgtcgattc aattctaggc caaacattta
     6241 ccgattttga attattatta attgatgatg gttctacaga taattcagga agtatatgcg
     6301 atgaacttgc gaaaacagac aaccgaataa aagtgataca taaggaaaat gggggtctaa
     6361 gtgatgccag aaatattggt attgaggtag caaagggaga ttttattggg tttatagata
     6421 gtgatgatta cattgatgaa gatatgtatg catttttata taacaatata ttgaaatatg
     6481 atgcagagtt atcaatgtgt ggtatttatg acgtccataa gaataaagaa attaaaaagt
     6541 taactccttt ttctcaattg gttactaaat ctgaagcaat tgaattagta ttagatggta
     6601 agctagttgt tgctaatgca gtaagcaagc tatataaaaa agaattattt gagaatgtga
     6661 gatatccaaa aggaaaaatt gctgaagacg cagcagtaat actgaaaatt atcaatcagt
     6721 gtaataaaat ccatgttgat acttctcaaa aatattatta ttatcatcgt ggagatagta
     6781 ttactagtaa aaaatttaca aaaaaagatt ttgatataat tgatgtatgg aatgagaatg
     6841 aaaaatggat tattaaaaat tatcctcaaa tgtacgataa agtacatact agagtttgtt
     6901 gggcttactt tgttgtgtta gataaattag ttttaactga agaaaaagga ctgtatcaag
     6961 aaaaaaaaca agtaagagag tatttaattg ataatttctt ttttattata aaaaataaac
     7021 gattaacttt tcaaagaaaa atatctatgt tattgcttac ttttggaatt gctgcgtata
     7081 aaataccggt taaatatcag tataagaaag taaaggctgt taattaatgc tttagttagg
     7141 atgaattaga tgaaaaaaag caggttagag tattctttaa taaattcttc tatatcaatg
     7201 tttatatata ttttaaggat agtaatacaa tttgtaggta gaagtttttt tatttatttc
     7261 ttaggagcga aatatttagg attaaatggt ttatttacaa atatacttag tttcttgtcg
     7321 ttggctgaac taggcatagg ctcttctatt atttattccc tatacaaacc attagcccaa
     7381 aaggatgaaa gtaaagtaaa ggctttaatg aatttgtata agaagacata tgaatttatt
     7441 ggtattttta tcggcatagt aggagtattg attattccgc tgttacctct atttattaaa
     7501 aatagcacag acataccaca tatgtatcga tattatgtat tatttttatt aaattcagtt
     7561 cttagttatt ttttcacgta taaaagatca cttgcaatag cagatcaaaa aaattatctg
     7621 gttgcgatta atgattttgc ctttttattc tttatgaaca ttgtacaagt aattgctttg
     7681 tacttttatt ctaattttac tctatttcta atagtgcaga ttttgtttac tctattttct
     7741 aatataaata tttccagaac agttgacaag agatattcat atttaaaaga gaaagatgta
     7801 gtttctctag ataagcaaac aaaagatgaa gtaaagaaaa atgtcatagg taatatgtcc
     7861 tcaaaaatag gcggggttat tgtaatgggg acagataata tattaatttc tacatttgtt
     7921 aatttaacag ctgtaggaat ttattctaac tattcattga ttgtcacaag tgtgcaaaat
     7981 ttatgtaagc aaattactaa ttctatcacg gcaagtgtag gaaattttgc tgtatcaaat
     8041 aaaaaaaagg attcatttga gctatttaaa aaacattttt ttatcaacca ctcactaatc
     8101 tttttttctt ctatattgtt attgacttta atgaatccct tcattagctt gtgggtagga
     8161 gccaaataca tgctacctat gtcaacgact attttaattg ttttaaatta tagtgtacag
     8221 gtttatagaa atacatcctt cgtttttata gagtcatttg gtttatattg gtctcaacgg
     8281 aaaaagccta taattgaagc aggtgtaaac ttgttattat ctttgctttt gttaatagtt
     8341 tttgatatgg gaatcaatgg agtacttata gggactatcg gatcgtctct aggatttgtg
     8401 atttggtatg aagcatttat catatataaa acggtatttg agaaacgttt tattcatttc
     8461 tttttaactt tctggcgaag ttttatagaa ttaataattt cggcaatagt cgtttttcta
     8521 ttaaatgaat atttagcaaa tggaggcagt acgttccttc aatttataac taaaacctta
     8581 ataactatag taacaacatc gatattatat ttgttattat attttagaag agaagaattt
     8641 acatttatca aaaaaattct ttttaggtat attttaaaaa aatagctttc tataaaggag
     8701 tgttttattt gaaaatagct atactatctc cagctttctc aatgggagga gctagtatcg
     8761 tggcctcaaa aattgcaaaa ggattaatag atagtggcca tgaagttttt tttgtttctt
     8821 acttagaaag tgaaaaacca caagtagaat ctaagtatta tgatttatac gaaaaaaaaa
     8881 tttttttatt taaaaatttt tctcgatttc ataagatatt agagtataga ttgtttggag
     8941 gctttgttcc tagtagatat ataaaaaaag aaaaagaaca actaaaaaaa gttctaaaga
     9001 aagaaaaacc tgatgtcatc atattcaata cttttatacc tagtgtacta ttctccgaat
     9061 tcctaaagta tgaatttcca acagtgaaat taattacttg gatgcactct gatcctgatt
     9121 acagcttaaa tcatattgct aaattttata aaaaagaata tagaaaaagt tttgaacgcg
     9181 tggattccat tgtttgtctt tcgcaagata caaaagaaaa actttcatta tacaataacc
     9241 atattaaagt tatttataac ccattgacat taagcggctc tagtttaata agtaaccttg
     9301 ataaaaaaat tatttcattt actgccagat acgatataaa tattaaaggg tttgattatt
     9361 tatgtgaagt agctaaaaac ttacctgttg gatgggctat aaggattgct ggagatggta
     9421 cagaagaaga acgtaaagag ctgaaaagat taattgagaa aaatggtgtg ttagataaaa
     9481 ttatttgcgc aggtgcatta tttggagatg aattaatcaa tcattatata gaaagttcta
     9541 ttttcatatc tacttctaga agtgagggac taccattagt gttgatagaa gcaatgactt
     9601 atggattacc tgtaataagt tttgatcatg gtggtgctaa ggaaatatta caagatggaa
     9661 attatggaat tttaattaag aattttgacg tacaagatat gaataatgag atagaaaaat
     9721 tgtctaataa tcgtttactt atggaaaaat atcaaaaatt ctctttagaa agagctaagg
     9781 attttaatga aaaaaaaata attggtgaat ggcaaacatt gttaaatgaa ttaggaaatg
     9841 aggatgttag aaattgagga cttcgattaa aaattttaat ttatggaaag aatggtatct
     9901 atatatattt tttataggga tgattattcg tgcaataaat ttttatagtt tattaccgtc
     9961 cacttttgat agtatttttt ttaaacttat aggaatttca ggagttttgc tattagggat
    10021 agatttcata attaaattta ataaaagaaa agtaacttat aacattttat tgatagcata
    10081 tatggtgatt ttagtaataa cgagttttgt tcataaagaa tatggtctag gagaaaactt
    10141 aaagactata atgtgggcaa tcttacagta ttttttgatt tatcagtttg cttttgagaa
    10201 tagcgataat aaacgatttt ttaaaaggat aagttgggga tttatttata gttggtttgt
    10261 tttagtatca atgtcaatgg ttcttttctt tggtaaattc ggctatgaga aatattataa
    10321 tgctagacat aggatcagaa ttggtttttt agaatcaaga ctgtttggga cgttttctga
    10381 tattaacaat gctgctatag catctttagt tgttattgtc ctaatcttat tttatcttta
    10441 taataaaaaa gtgacaggat taaataaaat cattttttta attaatcttc cattacaatt
    10501 tatttatata gtattaagtg ggtcacgatc tacctatgtg gtaagtataa taatagttgc
    10561 catatcatct tttattgttg tgttaaaacg aaatggaaca aaaaaagatt taaaaaacta
    10621 tatccttgct atagtatctt ctattggttc tgttctgatt ttattcgctt tgtttaatgc
    10681 aactaagata ctttttcaag aattattacc tcatttaaaa gaaataaatt tttttaattt
    10741 tacagagcgt cataaagaat taatgaataa tagtcaacat attaataata ctcaaacacc
    10801 tgataatact cttgttagga aagacgtagc tgaaaataca gatatttcta atgctagaat
    10861 tactatatgg aaaagtgcat gggaaatatt taaaacaagt tggcttatcg gagtctctcc
    10921 gaaaaatgta gtatcttatg cacagtcaat tattccagat ggatatattg cgaaagtagg
    10981 aattgccatt cataatgcat acttgaatgt attaacatcg acaggtattc taggaataat
    11041 tcctttcatg gcttttttaa taaagagttt tgtgctgaat gtttatcgaa tcatctataa
    11101 taaatgcatt ggtaaagatt atcattttgt ttactgttta gttattttat cttatgcact
    11161 atacgcagct cttaacaatg aattagtcta tgaaaacact gtaggaacgt ttgttttttg
    11221 gctattttta ggaagagtta atagcaaaaa taattctagc tatttttagt aataaatttt
    11281 atcttgaaaa gaggagaaaa aatgttgaat tacttgatta ccggtggcgc cggcttcatt
    11341 ggctcgacgc tcgcgaatta tctaggaaaa gaaaacaatg tagttgtgat cgatgattta
    11401 tcgatgggga aaaaagagaa tctggatgaa tcgaagcaca tcacgtttat tgaaggggat
    11461 gtcgctgaca aaaatttgat ggaaaaggtc atgaaagaat accatttcga ttatattttc
    11521 catctagctg ctgtagctag tgtggcagat tctgtagaac gtcctctaga aactcatcgt
    11581 gtaaattttg acagtgcgct tttattgctt gaattggtac gaaaatatca atctggttta
    11641 aaacgattgg tatttagttc atcagctgca gtttatggcg atgaaccaac gttgccaaaa
    11701 aaagaagaat cggtcatccg tcctttaaca ccatatgcca tcgataagtt tgcagcagaa
    11761 caatatgttt tggattactg tcatttatat gatgttccga ctagtgctgt ccgatttttt
    11821 aacgtttatg gtccaaatca aaatcctaac tctccatata gcggagttat ttcgattcta
    11881 gtggaccgat acaaaaaaca attggcagga gaaaaaacag aatttacttt atttggtgat
    11941 ggtagccaat ctagagactt cgtttatata gaagatgtta tacaagcact tttacttgtt
    12001 gctaaggaag aaaaagcttt aggacagcaa ttcaatgtcg gtacaggaaa aagcactacg
    12061 ctacttgaat tgattcattc aattgatcaa atcttaggaa cagagctagc gcttaaatat
    12121 gaagcggagc gttcagggga tattcgtgat tctttagcgg atatttcaaa gatccgttct
    12181 ttaggttatc aacccaaatt tgatatattg aacggaatgg aacgttattt aaagacagaa
    12241 atcgattgaa acaaaaaacc agcatcctgc tggttttttt gtctcgactt agctttttaa
    12301 attaacacct tccatcagtt cgtaaatctg atttcttaaa tcagtggccg gcaatttgat
    12361 gtttttatca gattggatat tactttccat gacgattgca tcttttgtgt cttttttcat
    12421 cgccgctact gcatggaatc gattgatatt tccctgagca aggatataat catttccact
    12481 gtaaacaccg ccgctgtaag gatgtttatc accattattt tgccacaatg agaaaagtag
    12541 ttcttttggt ataatatcgc cagacagaac actggtaaag aatttgttca agtcataaac
    12601 agacatactt atatttcctg tgcctaattc atttcggatg tctgtttcag gctcgaccaa
    12661 tgcttttgaa taatcgtcag ttgcagacat ttggtaagat acagcatgct gaggggaatt
    12721 ttttacattt tcataaaaat ctgtatgttc tagatggagt ggccgaatga tttctttttt
    12781 taaaagagtt tcataaggct gattcattag tttgatcaat acccctgtaa gcaatgtata
    12841 atttaatggt tcataatgat acgtatcata accagtaaat ttcaaatgat gaagggcaaa
    12901 ctgaatgatc tcactatctg acataggttt ttttggagaa gcggttcgat gaagaccaga
    12961 gcgcatgtaa agcatatttt tgattgagat ttgctgactt ccaggaatct gaggataaaa
    13021 ttcagatagc tttgtgtcaa aagttatctt gccagattga atttgtttta ggataagtaa
    13081 agcagtcatc gctttttgga tcgaaccgat ttgatagtaa agagaaggag aattcgattc
    13141 ttttatgcgt agatttgcgt acccatatcc tttttctaat atcactcgat tatttttgcg
    13201 tacataaatc gaaccgatat aatctgattt ttgcagtaat tgatcaattt tgctggcaag
    13261 catctgctca ttagatgtta aattggaagc aagttgtgcg ggttccgttt tataaatttg
    13321 tggttgaggt tgttttgtta attgccatcc tgtaatgatg cctgttgaaa agaagctgac
    13381 agccagcaac aaaactgcga gaaaagaaag agagatctgc tgtttttttt gatgttttcc
    13441 ttttgccata ttaaatcctt cctatccatt tttaactatt tttcattgta atcctcaaaa
    13501 agagcatttg ccacttacaa ttttgacata atatttggta aaataattca cggcagtaga
    13561 aatttcatgt ataataaaca gagttacgaa gatgatagta aggaggagtt gttttgtcag
    13621 gaaacaaaca acacccaagc aaagacaaaa aagaagccag taaggcagct acagcagata
    13681 taatcgacaa gcggagaaat ctgcgtaaaa aagaagataa gatcgtgagg aagatcattt
    13741 tagtgatcgc tcttacatta ttgattattg gcggatttct cgggtttacc gtatatcgtt
    13801 atgtagatag cgggttgaag cctttagata aatcggacga ccaattagtc caagtggaaa
    13861 tcccaagcgg ctcttctaat aagcagattg gcgaaatttt ggagaaagac aatattatta
    13921 aaagtgggat tgttttcaat tattatacaa aatttaaaaa cttaactggc tttcaagctg
    13981 gttattatca gttagcgcct aatatgactc ttgatgagat tggcaagcag ttgcaagaag
    14041 gcggcacatc tgagccaaca aaagttgcag atgggaaaat tgccattcca gaaggctacg
    14101 acatcgatca gattgctgag cgggtagcga aggtaactgg taaagacaag aaagaatttt
    14161 tagatttagt aaatgatgag actttcttta acgagttgta tcaaaaattc ccagaattgt
    14221 tggaaagtgc ctctaaagct gagaacacaa aataccgttt ggaaggctac ttattcccag
    14281 ctacttatga ttactacacg agtacttcgc ttaaggatct tgtgattgag atggtgaaca
    14341 aaacaaatac ggtcatgcaa aactattatt cagctatcaa acagaaaaat ttgactgtac
    14401 aagaagtttt aactttggct tctctagttg aaaaagaagg cgtaaaagaa aatgatcgta
    14461 aaaatattgc acaagtcttc tttaaccgaa tcaaggcaaa tatgccactt cagtcagata
    14521 tctctgtttt atatgcatta ggagaacata aagaattggt gacgtatgaa gatacagctg
    14581 tagattcacc atacaatttg tataccaata ccggctatgg gcctggtcct tttgacaatc
    14641 caagcgaaga ggcaatcaag gcagtattag aaccagcaga aaatgactat tattatttcg
    14701 tagcagatac gagcactgga aatgtttatt tcgctaaaac gtatgaagaa catatggaac
    14761 tagtgcaaaa atatgtaaat aattcttaga aaaacagggg ctagtcattg atcattttta
    14821 gaaaaacatt tacattttaa gaaaagcgtg gtaatctttt ttggactata ttcctcaaaa
    14881 gattaccttt tgcggtattt tatcgaaaaa aggagacgtt acacatggta gagaaagttt
    14941 atccaatgac tctagaaggt aaagaaaaat tagaaaaaga attagaagaa ctaaaaacag
    15001 ttaaacgcgg agaaatcatt gaacgaatca aaatcgctcg cggtttcgga gatctttccg
    15061 aaaactccga atacgaatca gctaaagatg aacaagcatt tgttgaagga agaatcacaa
    15121 caattgaaaa tatgatccgt tttgcacaaa tcatcgataa tgacggcgta gatgcagatg
    15181 aggtatcgat cggtaaaaca gttacgttca tcgagttgcc tgatggagat gaagaagagt
    15241 acacgattgt cggaagtgct gaagcagacc cgttttctgg aaagatttcc aatgattctc
    15301 ctatcgcgca agcattgatt ggcaaacgta aaaatgatga agtaaccatt gctacaccag
    15361 gtggcgatat gttagttaaa atcgtcaaag tagaacaagc gtagtctgac tgaaagatct
    15421 agagagttca tcttactgat gacgcactct agatcttttc tctttgagta ttgcaggttt
    15481 cactgaacga tcttacatct aaagtcctat agccaacagt caaaaaaata ggtatgatga
    15541 aatgagaatg tgtcaggagg gagaaaaagc gatgaatagt tcttggcgtt tttttgtggt
    15601 agtcgaagca ctgctgctgt tatttgctgt ttggcaaatc gtaaacaata ctggactttt
    15661 gcttttagta atattcggta ttttcaatat atatctagct atgcgcaaat atcctcgtac
    15721 taaatttcaa aattttcaat tgatcttagg gagcttggtc atttttttta gcttagtcaa
    15781 cagtcctgct ttatggatga tggttgtatt ggccgtttta tttatcgggc tgaaaggtgt
    15841 agagatttca ggaatagatt tgacaaaaaa tgctttttgg cgaaaaaaac agatcatgat
    15901 ggtccaaaca gagcaattaa aaacacataa taatgagcgt aaaagacagc aattatttgg
    15961 taaccaacgt attggaaacg acgtctatga atgggatgat atcaacattg ccatcatttc
    16021 tggtgatact atcatcgatt tgggcaatac acttttgcca aaagatgata atattgtgat
    16081 tgtaagaaaa gggataggca gaacacggat cttagtaccc ctgggagtgg ctattcgttt
    16141 agagcatgcg acattagtag gaaatgtctt gtttgaagaa gagcagtttt ccttaaaaaa
    16201 cgaacagatc aaaatctgca gcagtgatta tgatgaaaat cctcgcagat tgaagatcat
    16261 taccaatact ttggttggag atatcgaggt gatacgaata tgatgggaag aatatccaaa
    16321 gcaatgctag ctgtttattc ggggattgcg gctttcctta ttattctatt ttcacttttc
    16381 acttattttt atgccagtaa ccaaagtcat tggtggggag aattgctgcg tgcgcgttta
    16441 ttatacgttc cgcttatctt ccatttgatg gcaatttcat taggtgtagg attgatcgta
    16501 tttctattgt tatcacttat tcaaaaggca aaatacggga aaatcgaaga aaagcttcgt
    16561 gcactttctt ctggcaatta tgaatccaaa cttttgcatc agccgatccc aagcgcgtcg
    16621 gatgatctgt acatcaaaga tattgatatg gaaattacta aaataaaaga aaaaatgatc
    16681 gaagtatcca gtgaattaca gattatgact agccgtcctc aatatgtaga tggacaaacc
    16741 aaagaagaga ttttaaaatt agaaaggcat cgattagctc gtgagcttca tgattcagtt
    16801 tcacagcaat tatttgcagc gatgatgatg atgtcggcat tgacggagca agcagaaaaa
    16861 agtgagacac cagaaatgtt ccgtaagcag ttgaaaatgg tggcagagat catcaacgct
    16921 tcccagtctg agatgcgtgc gctgcttctt catctgcgtc cagtcaattt agaagaaaaa
    16981 agtttaaaac aaggcattga gcagttattg aaggaattgc agaataaaat ccagatttcg
    17041 ctaaaatggg aggtagaaga tgtaaaatta actagttcca ttgaggatca cttgttccga
    17101 atcgttcaag aattgttatc aaacacatta agacatgcta aggctaatga attagaagtc
    17161 tatttgcata aaatagataa caatctttta ttacgtatca ttgacgacgg gacaggattt
    17221 aatatgaatg aaaccaaaac gggaagttat ggattgaaca atatcaaaga acgagtagct
    17281 ggtattggtg gaacagtaaa aatcattagt tttaaagggc aaggtacgag cgtggagacc
    17341 aaggtccctt tgatgaagga ggcatagata aagatgataa aagttttatt agtagatgac
    17401 catgaaatgg tacgcttagg cgtctcttct tatttatcta tccaagaaga cattgaagtg
    17461 attggagaag ctgaaaatgg acgtcaaggc tatgaaaagg cgatggcact tcgaccggat
    17521 gtcattttaa tggatctagt catggaagaa atggatggca tcgaatcaac aaaagcaatc
    17581 ttaaaagatt ggccaaaagc caaaatcatt atcgtcacaa gttttattga tgatgaaaaa
    17641 gtttatcctg caattgaagc aggagcagca ggatatttgt tgaagacgtc tacagcacat
    17701 gaaatagctg atgctataag ggctacgcaa cgcggcgagc gagtactaga acctgaagtg
    17761 acaacaaaaa tgatggaaaa aatgagtcgg cgaaatgatc cagtattgca tgaagaatta
    17821 acgaatcgag aaaatgaaat tttgatgctg atttctgaag ggaaaagtaa tcaggaaatc
    17881 gcggatgaat tgtttatcac actgaaaaca gtcaaaacgc atgtgtcgaa tatattagct
    17941 aagttagagg tagaagaccg aactcaagca gctatctatg cgtttaaaca tggtttggtg
    18001 aaataaaaac gatgataaag aggataatca aaagctgaga aaataactat tatttttctt
    18061 ggctttttta caataatgat gcttgctttt gtttttggaa aggctttgtt atactgagaa
    18121 aagaagatac taaaggagga aaatggtgaa acaaaatttt gcaattgtag gccttggacg
    18181 atttggcgga agcatctgcc gtacactgat cgaagctgga caagaagtac tggctattga
    18241 cagtaatgaa gatcgagtca atgaatatat gaatatagcc acccatgctg ttgtggcaaa
    18301 tgcacaggat gagatgacac ttcgttcatt aggtataaga aatttcgatc atgtaattgt
    18361 cgctattgga gaagatatcc aagccagcat cttagttact ctgatggtaa aggaaatggg
    18421 cgtaccgaat attttagcaa aagcccaaaa tgagtaccat gcccgtgtac tagagaagat
    18481 cggagcagat cgtgtcgtac accctgagcg agacatgggg atacggattg cacataactt
    18541 agtatcaaag aatattctag actacttaga gctgtcagat aaatattctt tagcagaaat
    18601 ccgagtctcc aatcctaaat ttttcaacaa aacattagct gaattaaatt tcaggcaacg
    18661 ttttgactta acagtagtcg ccatacgaag agtagatcaa acggttatcg cttctcctgc
    18721 agcagatgaa tatgttcgtg aaaatgataa tctactggtt attggagaga caggcgatgt
    18781 ggatattcta gacgataaga tgaatcaata gaaagaaaag agaaagtagg ttgttgggat
    18841 gaaattaacg gtaacgccaa aagcacaaaa gtggtttgac tcagaaattg atctgccaga
    18901 aacttacgga atacgttttt ttggaaaagt ctacggcaaa acagaggttc atgatggttt
    18961 ttcgattgga atgtcagttg aacagccaga acatcctgta aagaaagtgg aaatggatgg
    19021 gacacttttt tttatcgagg aagcagatga atggttcttt aaaggatatg atttacttgt
    19081 tgattatgat cccaacctgg aggagccaac ctatcacttt aaaaaacaat aaaaaaagag
    19141 agggtgacac aatttttgtc accttctctt ttttcttttg aaaatattgt tttcagctat
    19201 taatatcctg cagacaattt tacttgattg gtttgaagct catgggtggc aaagtagctt
    19261 ttcagattgg ttaaaaaaat agccattaat ttcttttgaa aatc
//
LOCUS       DACGMI010000058        18968 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.060, whole genome shotgun sequence.
ACCESSION   DACGMI010000058 DACGMI010000000
VERSION     DACGMI010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18968
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.060"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(341..2311)
                     /locus_tag="IXT46_002262"
     CDS             complement(341..2311)
                     /locus_tag="IXT46_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948161.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            complement(2326..3192)
                     /locus_tag="IXT46_002263"
     CDS             complement(2326..3192)
                     /locus_tag="IXT46_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948162.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            complement(3182..3415)
                     /locus_tag="IXT46_002264"
     CDS             complement(3182..3415)
                     /locus_tag="IXT46_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4948163.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            complement(3427..5583)
                     /locus_tag="IXT46_002265"
     CDS             complement(3427..5583)
                     /locus_tag="IXT46_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948164.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAENVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            complement(5603..5824)
                     /locus_tag="IXT46_002266"
     CDS             complement(5603..5824)
                     /locus_tag="IXT46_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948165.1"
                     /translation="MVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            complement(5934..6272)
                     /locus_tag="IXT46_002267"
     CDS             complement(5934..6272)
                     /locus_tag="IXT46_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948166.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNELLG"
     gene            complement(6672..10313)
                     /locus_tag="IXT46_002268"
     CDS             complement(6672..10313)
                     /locus_tag="IXT46_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948167.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPAPDN
                     QENNQETVINKSVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGELLKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGQDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEDDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTALKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKPSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            complement(10316..12265)
                     /locus_tag="IXT46_002269"
     CDS             complement(10316..12265)
                     /locus_tag="IXT46_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAQ4948168.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKAEDKDNEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQM
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFR
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            complement(12307..13365)
                     /locus_tag="IXT46_002270"
     CDS             complement(12307..13365)
                     /locus_tag="IXT46_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HAQ4948169.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLEERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            complement(13484..13939)
                     /locus_tag="IXT46_002271"
     CDS             complement(13484..13939)
                     /locus_tag="IXT46_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948170.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGMKKGR"
     gene            complement(14523..15326)
                     /locus_tag="IXT46_002272"
     CDS             complement(14523..15326)
                     /locus_tag="IXT46_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAQ4948171.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            16306..17529
                     /locus_tag="IXT46_002273"
     CDS             16306..17529
                     /locus_tag="IXT46_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAQ4948172.1"
                     /translation="MESYQFQIFKLVPSLERRGNRMKITEKNVNPKFEPTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLEDHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            17564..18331
                     /locus_tag="IXT46_002274"
     CDS             17564..18331
                     /locus_tag="IXT46_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAQ4948173.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LNIDFAKVRKGRNYNFAVQFNISSEFDEKTYREKKLG"
     gene            18523..18921
                     /locus_tag="IXT46_002275"
     CDS             18523..18921
                     /locus_tag="IXT46_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAQ4948174.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
BASE COUNT         5732 a         3621 c         2747 g         6868 t
ORIGIN      
        1 aactctcgct ttttcttcat cagtaaagtt tttatacaac tgattacaat aatgaggttt
       61 ttgaagtttc tgaataccta tactaacttc aaatccttct tcatgttgaa ttaggattac
      121 ttctgtgtct ctacctagaa atattcgatc taaaattttt atgtttggtt tcattattta
      181 acctccacta taattatttc actcagtaag gtttcacttt atgaaatttc tatagttctc
      241 ttttcacaaa acgtaccatg ttctctaaga ctgtttttag tctcaaatat acatgttttt
      301 tcttatcctt tccttataca ctcaaaatca aagataaaac ttaaagaata aactctccaa
      361 taacaaaatt attagtcaga tccactggtc tcctgatctg aaatttatta cttcttcctg
      421 ttgtcaaata ctgtctcaaa tcaacagaaa gtttttgatc atcttctcct tttctagcag
      481 gagcaacttt tttttcatac ttcattaact ctccactggt catctttcca atgatagtgt
      541 aattaaaatc actttcaaaa ctttggtaaa tttttccatc tgtattgaat atatcagctg
      601 tttcaatatc ttctttgtat tcattgtctt ctcctgaacc gattgtatca aatagaaagg
      661 caagacgaat tccatcttct tcaagcattg ttaatctttt tttaattagc ccaacggttt
      721 caatagataa cttatcgaag ccgtgaatca taacaatatc atcttttttt gcttgtgatg
      781 tgatgaaatc aaaggtattt aaaaattgag cttccataac attggtttct gctcttagat
      841 cacctaagtt atagtaaaac tgtaatttgt cacttttacc gatttctttc agtgtcgttc
      901 tttgattaaa catcctagag aagctgtcta atgctgttct caatgtgtct tttaatacaa
      961 taatacgatc gacttctttt tcagtaccag attttttggc ttttgtttca gcattagtca
     1021 aatagctaat aaaatcccca agaactggca ttgtatcact actgttcacc aaaagttttg
     1081 aacgttcttc ataattaata tcccaaagtt tctgacttat ataaaagtta cctaattctt
     1141 ttttcaataa aactctagtt gcagaatcta atgttctgcc tgctaacaaa taaaaaatct
     1201 gagttagttt atcgagattc cgtctatata aatcaccaat gtccttttga ttaccaaaaa
     1261 gctccaaaga gttaagacct tcttcagcca aattaacctt ttctattaca ctgtttaacg
     1321 aaggtttggc aacaaatgtt ctaccagttg gatcaccaaa gtaatcaaat ttatttaaga
     1381 caatatgaaa agttcgttta tgatttgcca ttgcattatt agcaatcaat tgcccccaaa
     1441 gtgatgatgc tgagattttt tcatcatagc ctttaattgt agcgtttttg tgtgatgcca
     1501 ctaaaacttt acttgtaaaa gaatcatcca gtgccataaa agctacacca cttgcgtagc
     1561 tagtagacat agtgccgata gcccatccat tcgcatcatc taaacctttg cgaattgcat
     1621 gatcatttcc tgcaaaatcc gaactcatag acgtatactc atagacattc ccgattggtt
     1681 cacttaaaag tctatcaaac agatcacgtt gatctcctcc atatgacata agctttaatc
     1741 catacatttt ttcatcatac aaccgttgga gtttaattag ctgttcgctg attttattag
     1801 gagaatcgga tactaatagg atttctagct tccaatcaat aattttattt gccatgctgt
     1861 ctagtaaaga tgctgtattc aaatccataa tccgcataac agttttgcta atttcagcat
     1921 ctgaattttt tccttctaaa ttattttcat aactattcgt tgatccccca acattctcgt
     1981 gcattatttc ttgttgatct ttttgtgaca ctggcttatc tgcttcaatt agataggctt
     2041 ttaccccttc tactctcact tcaggaatag ctttaaccat ccaaccaaat ccataatttc
     2101 tattcattcc ataagtattc actaatttca caattgttcc ccaccgctta cctgtcctaa
     2161 tgtaagatgg tgtaaattga taaccaacta aagatgttaa atcactaaca aaggtattat
     2221 tcactacctt tgaatttcta gttttttgtt cttttttagt ttttctcttt tttttgaaat
     2281 ttaatagttg tgatctaccc ataatttcca tttaatctct cacctctatt tcagtgcata
     2341 aatatcagat aatatttctt ttgtttgttt agctgacaac tgagtgacac tataataaag
     2401 tcctctactc gtatagtttt ctaaacgttc cacaccttca tccaatacca tcttagattg
     2461 agatttcaag ataagatatt ggattactgt tgttttcaca ccatcaatat attctgatac
     2521 aaatcgttct tgctgatcta ttatgtcaaa gactgctttg ttactccttg catttcgttt
     2581 ttgtattttc atatttcgag tttgtctttc cgtattctga ggttgagatg aagtgatttt
     2641 gatttcagct aaggaacgat ctctggtatt ttgatattgt attgatttcg attcctgagc
     2701 cataacttct tctggaaaag cggttagtga tgtagcccca tctagattga acattaatgc
     2761 tacactccca tctcgatata cgattgttcc atcttgtttc acttttaaaa tctctgtgcc
     2821 tcgaaatggt ttctttttcc ccatagatac tcttgctgaa ttaactactg atttgaacag
     2881 tctaatagaa ccagaaatca atgaaccact agatggatca ataaacatat actggctaat
     2941 tagaataaga aatccaatta tcattaataa cgttggaaca aaaataaatt tcagtttaat
     3001 cgtatcagaa actaagtaaa caattgatcc aagaacaacg actgcaacaa ctatagctga
     3061 tacaattaat ctttttgctg taacagaata ggtgctattg acatgctttt caagccattc
     3121 aactctgaca attgtttcag aaggtttttg atgtaagtta tgtttaaatc catagtttga
     3181 gttatctgcc atcagaaata cttcctttca cgttcaactt acggtaaaca cctacagtta
     3241 tcactattgc aacaataagc aagccaatta aagatattga cttgctcatt gtctcgttcg
     3301 tttgtggtag ttcatttacc tgatacacga gctgtgcttc ctgtaagtgc tgagaagagg
     3361 tcatgttttc ttgattgttt tgaattactg gataaactat tttttcttct cgcataatag
     3421 ccctccttag ttattatcag ataagtgagc ttgaattttg tactgatttc cgtctggagt
     3481 tttcacaact gctttttctc catcaataga aatcacttca gccttagttg ttttcccatc
     3541 aatactgatg acaacatctt tcccaacttt gaactctgta gttggtgttg cttcatagct
     3601 actatttgtt gaagcagagt tcgtatttgt cccaatcgaa ttttccactc tcgaaataga
     3661 tgtttgagtt tgagcctgtg cttgttgatt attatgacta ataaagtagg acgatcccaa
     3721 gatcgttccg caagccattg cagcgacaga aatgatagta gccatctttt tacttgtaaa
     3781 atcacgtttt gaacttgatt gattttctgt agcaactgct aatgatttcg ttttttctgc
     3841 catttgagct agatcacttc gggaacgaga taagtcttct cttaaagctt cactttgttc
     3901 tgccaacttt tcgctattta atttataacc ctctgctaaa tctttgacct ctttcattcg
     3961 atctttatat tcttcgatag ttttttgttg ctctacaagt tttgtttcta attctttcgt
     4021 gttgttagct acctgctttt caacttcttc tttgttcgca aaatatttga caaccacatc
     4081 tgttgttttc tcttttgtat catggaactc agcttcattt tctgactttg ttttttcgac
     4141 aatctctaaa gttttttctt gcacgtctgt taatgatttt tcaatttctg gtttcaatga
     4201 attgataatt cgttccacca caacttcttt tgcttcttgg ctttgtttca atgcatcgtt
     4261 tttaatagat tcaattgctt cttggtactg ttgatcaaga ctttcttcag ttgcttttct
     4321 atattcatct tcttgttgtt taacttctgg taaatgctca gcatcatacc gttgctctag
     4381 tttctttagt tcagcatcca aataagcctg tttcgccata tcataatctt tacgaatgat
     4441 attggatttt tccatcacta aatcatcaat tttagatgct tctgcttcgt agctctcttt
     4501 agcaaccgat agtgtatttg taaactgatt ttgaccattt aatgaggttg cttcctctat
     4561 ccgcaaaagc tcatcagcta acatttgctt tcctttgagg atcaattgct ccttcgtctt
     4621 atttaattca ctgttgattt tattattagc aatagagatg cgagcgttca tactctcttt
     4681 agctaaaaac agcaatggtt tcaactcagg tatggatagc atctcctcgt ttaaatcgac
     4741 agggtcatta atctcatcta aaactacagg ttgaaatttg tcagcaatga tctgttcaaa
     4801 atttttttct aaaaaatcag catctaagtt tttcggtaca tcactttcag atgtgatttt
     4861 ttcagcttca taaacataat tttctttgtc actttgggat tcgggttttt catcaatttt
     4921 tggttgttgg taggtttctg tttgtatttg tgtttcttct atgcttactt cttggttttc
     4981 tgcttcggtt ggtttgttat catccacaaa aagagcttct ttttcatctg gtacattttc
     5041 tgctacggct tcaaattcaa cttcttcaga agagttgaag gtctcagcaa ttcgttctaa
     5101 tccattagta gctacttcta attgctctac tgcgctatag aagtctgtag cttcttcaac
     5161 ttctgattca aacacattag gatcatccgg aataactaat aattgaccac tactatccat
     5221 aaaacggaca cctgctaata gcttctcttt aaatttttct ggtagatcag ctacataatt
     5281 caaacttgac ttcaatagaa cgacatactt ctcagaatcg agaatagcat catcctcatc
     5341 tataactccc tcactgttga gcttttgtac atcttcaatt accatataat ttttctttgg
     5401 taaatctttg gtcagcaacg catcgaattc tttccatacc tttgctttag ctttttttgc
     5461 cttcgcttct ttttcttctt ttttgtacac ttcgagtaat tgtggcttca aagagagtgc
     5521 aactacagga actgtttctg ccacataatt aatagattcg gtaatatctt tgaattttgc
     5581 cattattgta aaactccttt tttcagtcaa tagttctttt ctgtttatct agcatatata
     5641 catatgcttt ttcgaattta ataagcgttt caagtctggc tttttcaatc tttttactcc
     5701 catttcgata atcatagaac tggttaacat tcatattcat tatctttgcc agttcggtac
     5761 ctttcagact gctcattaat acttcgttgg cgtgagctaa cattttttct ctatcaaaaa
     5821 ccatcttaca tttactttct tccctcactt ctaaactacg cttggagcgt agttttttgg
     5881 taaaaagtaa attgaacaaa tcggcatatt atccaaattt gttcaattca cttttaacct
     5941 aacagttcat tttttggaaa ttttgaaact agatagatac caacaactgg aataagtgct
     6001 gatatgatat tagctttttg gttcaaatca ttacctgttt tagtacccat tgtgtaaagc
     6061 ataacggttg taattacagg aataataaag attgcaataa tcgccccaac atattttaat
     6121 ccatctcccc attttgcatc accaaaaaat ttcattgcag tgaatcctgg tttcaacgaa
     6181 aaaacgaatg ccaagaaata caaaacaact tgtactaaag ttttcatatc aggcgtcatt
     6241 ccgctaacca aatttttaat agaatcgaac atataaaaac ctccttttta atatttttaa
     6301 taagttaatt atatcatcga caaatcttat ttgttcactt gtcaatgatc taactaagaa
     6361 aaagacgtct cgatatttac atctttatgt tatcataata acataaattt tcgatgatta
     6421 aaagagattt tccattaaat tatttcactt tttttattgg ctaaaaatgc tggtttatca
     6481 agtttttgtt tatataataa ttctgttctt taccagcata agcccttttt aattatacaa
     6541 ctttgaacag taaatattta attcatttat agacaattta aaataatttt tttgcataaa
     6601 tagaaatttt ccttgacatc ttcagttaga aatcaaagta aaaagaagga gcaaatcaat
     6661 gctccttctt tttactcgtc ttcagactta ttttcagttg atttttgatt accgtatttt
     6721 acaatatagt ccttgactga catggtagat ttcttcacta ctttaccagt tttggatgct
     6781 cctgtagcag tagccttggc aaccttagcc gttcctttac ctattttaat agcttcgttt
     6841 ttagcttcat aggttatccc tgctagacta ccttttggag cttttgctaa agctttatct
     6901 gctgaggtgt aaacattttt accagttttt gatagatatt caacggctga tttagctgtt
     6961 gatggtttct tggttgattg attagatttc cctgaattat ctgaagtaga tttagaatta
     7021 tttgttctat tatttttatt tgtcagttca ggttctctaa ttgattgatt gtctttcgac
     7081 attcctgatc caatatttgt ttcatattta tctgtttgat taacattagg agtaggaatg
     7141 aactttttct tcacatctga ttgttcttta tccgtttctt ttgttagcga ttctctgtct
     7201 ttaagtgctg tgtcattccg aatagcacta ttatcaaagt tgctgttaag ctctcttgac
     7261 tgactttcac cagatgctcc atctcctaat tcccgatgca ctctgtctga cacgtcctca
     7321 ccactcattt cattcctcag ttcttgatga gtttgatcta aagtaatctc gtcatcttca
     7381 ttctcaggaa ttgcaacagc aattggcgta tgtcgttgtt gttcgagttc tctatttcga
     7441 tctgccacaa gcgcatctct cgtctcaatg atattcccat cctcatcgac taaatctcca
     7501 ttcacattat atccatcgct gtgtttacca agtttattac caaactcatc aacaagattt
     7561 ccatcttcat caactaaacg ccctttttcg tcaactaaac gtccgttact atcctgacca
     7621 aaatcaccat ttagcaacct gcgtccattt tcgtcaacaa gatttccatc ttcatcgact
     7681 aagcgacctt tttcatcaat taaacgtcct tcgctatcca taccaatatt accatcttca
     7741 ctatcttcca atggtttacc attagtatct ataaggtttc catcttcatc gaccaaacgc
     7801 cctttttcgt caataaagtt gcctttagca tctttaccgt atttactatc ttttaataat
     7861 tcaccatttt catcgacaaa gtttccgttt tcatcaacca tacgtcctaa atgatcaata
     7921 tattgttggg agttattacg tagttgatct tgacgaacta aatctttgaa agaggtatta
     7981 ttgattgttg aaccaactcc gccaccgttg aatgacattc cttctggtgt ttcaggaatt
     8041 actttatcag caatggactt agcatcagca ttgctatctc ccatattgtt caaacgttca
     8101 gccatttttt gcgctccaac tgctccaaga cctcctgcaa ccatatcttt tactgagctg
     8161 ttgccaccat cataataggg atttttagct ccttggcttt tcttgattgc tttagaaacg
     8221 ccgtccacaa ctcgcacagc atcatttcta ttaccaaata ataacttagc acgttcatca
     8281 aacccaaacg ctacttcaag tggtaagcca ataagcatat taatcaaatt atttactttt
     8341 tcgccttttt taaagactaa aagatatcct acacctaaaa tcatagcaga tcgaacaata
     8401 tttgctacgc catcgccaac taatgtatta ggaatgaatc ccacagcagt atcaccaaat
     8461 gcacgaataa aagtaatcag aaagataggt aattgtagtc cgatcagaga tgttgtaaca
     8521 acacctaatg aaattgccat cacacctgct cctgatgcaa gtgatcctgt tagaactact
     8581 tcccaaatcc gaataaattc acgtttaaat gctttcacga tattcacatt gaacatcgcc
     8641 caagcacatg ctaagtaaag aactgctaaa acgattgatt cagcgttcat cgctagccac
     8701 gagccaaact tacccatcgc tccatgacca actaaggatg ctgtacgcca ttctgttttt
     8761 actgttgaca tattcttagc actgccttga attcctgaag gagcgatatt atacgcataa
     8821 aacttagctc ctgatgtatc aagtgccgat tggagcaata aagctaccga ctgtgtgcta
     8881 aaagttgcat tgttagcaac gccccaaggt tgagtagcat caaagttatg cgctgttcct
     8941 tttccatcag gcttgcgatt gtcgtctgtc acattttgat ttgctgacca aatatatcca
     9001 tttaaattgg ttggtttctt aattgcactt ccttcttttc catcccctaa attatagcct
     9061 gtccaaacag caggcgctct tcccatataa gcatcatttt cggcgacatt aacatcaccg
     9121 gcataagtat taatattgaa agtatcattc gatgaccatt cttttaatag agccataccg
     9181 actgaattag aatctagatc attattttgt ctggcataac tgctagtatt gatcgctctt
     9241 atcattgcag attttttaga tggttcataa tctgtatcaa cgaacttgat ttcggatgta
     9301 ggctttccgt caggtacatc accaccagta tcagatgatg gagcaagatt ttgagtagaa
     9361 gcccaaagtc ttgtgttaat gatgtagtca gaaacaacat ttgttggtat atctccatct
     9421 ttttttgctg actggatgcc gttgatataa actcccaata gcgatcctgc cactggtaag
     9481 aatataaaca atacaaaaat acgaacaatc catttttcaa gtactggtga taatcccttc
     9541 gagttaacac catctttcga caataatttc attccttgat aacctagtat tgctgtgaaa
     9601 aagagcatag ataagcttgc tatcgcttta aataattcat tatttaatcc caaattgtta
     9661 agcaagctag ttaatgcttt agataccgga ttagatacat ccgatccacc ttctccccac
     9721 cccataagag aaaatatatt catactcatg aaaaattttc caaggagttc atttatggat
     9781 tcagcaatat tagaaaggat taaactaatt gatccgataa aactaccaat cgtcctacca
     9841 atacttccta gaatggatga tgcttgactg gcaatagcat ttcctgagac tgtttcaata
     9901 tatccatagt aactataagt tgctagagta gatgctagtt gtgtacctgc attcccccct
     9961 gcaatcgaat taccttgttt agaaatatca gaataaggaa aatcagcact gataccacct
    10021 tgtcctaaca aattcatttg tccagtttta gcagcactat cattgacttc tttatctccc
    10081 atcaagatac gagcatatag tgtccacatc ccttgttctg ccggtttact ttccgcataa
    10141 gcaacgctct tatttataac tgtttcttga ttgttttctt gattgtcagg agctggatca
    10201 ttcattccaa atggagcgcc taaagttact gctaataccc ctccaataac tagacctctt
    10261 acgacccatc gttttattct aaggttttgt agtaaatatt tcttgaattt catagctacg
    10321 cccctccaat cgaaaataca atcttgtttt ctttactttc agcaacggaa ggctttgcaa
    10381 taatttcagc attagaatca ccttttcctt caaacgctcc agcttcactc aacttaacat
    10441 cgaatatttt tgcgtttgga taagtaatta ttgcttcagt aatcgcttct tcaaactcag
    10501 attcaactaa atgcaagata ttccttgcac cccctgattt agaatcctct tgtgaagcca
    10561 tgtcaaaaac taagtgcatg gagagatcgt ctgcataaaa attttgacca tatactcttt
    10621 ctttcctagg tggaagacgt aagtctatat ttaaatgttt tcgtactaat tcagcactct
    10681 tcaacatttc attataagca atttccagaa gagtttgttc ggataaagcc caaaatggaa
    10741 ctattcgtcc aaatcggtta ataacttcag gctttagacc ttcaccaatc aaggcttgtt
    10801 tgatccctga tgcgactttt cggtattctc tttttagttc agtgctgtat tcattagaat
    10861 tttccttgtt tgtaacacga gatagtgagc tatatcggtt taacgaatcg aacatctccg
    10921 cacctgcatt tgttgtcgca aataaaattg tatttgacaa tgaaacggtg tcgtgaactt
    10981 ctcgatcatc ccatcctctt tcagtaaaac ttatcctacc ttcatctaaa attgataaaa
    11041 aggcatcgag tgtttctaca ccagctttct catattcatc acacacaata atcgcagaag
    11101 gatcatgcct tacatgagta cctatgagtc gtctaaaacg cattgcatca tctttggttt
    11161 tgtaatccgg catattaact aagagaactt tattttcatc gccataaagt cctcttgcca
    11221 cggctttagc cattgcagtt ttaccgaccc ctgttgatcc tgtaaacaga gcagttgctt
    11281 ttggttgctt tcgaccttta aaacgatcaa atccaagctt catacgttta aacaacattg
    11341 ttatagtata aactgctaac ggttgtcctt ttatggactt taattcctct tgaagttttt
    11401 ccatatcaaa atcagaatct agctgaatat tatacttacc aaatatttgc aatagacttt
    11461 ctcgattata agcatttccg tctactcgat cttttgcaat caaatcctcc attacagcaa
    11521 ttgatttagc cggttcggac aaatcctcac gataaagttt gtttgcttgt acgatttctt
    11581 gaagtaattc atcaggaatc ctttgcgata atctaaaaga agcctgagga tcatctttaa
    11641 cagaggatgt atttagccat tgtctcaaaa tatcgacgac aacatcgctt tttagttcat
    11701 tcaattctaa cggttgtagc cgtctcccta aggcatcatc tcttttgata tagttttcat
    11761 attcttttct tgtagtagcg gtaatcattt gaagtgattc atttgctaac ggttctttta
    11821 gcgaatcacc cccaatttta ttgccactcc caaaagagct aacaacttta tgaaactcgt
    11881 caatgaagag gacaaattca ttatctttgt cctcagcttt taaaattcgc tcatattctt
    11941 tcaatcttgg aattaatgtt tctaaacgtg tttggaggac atcatctccc ccaacacgca
    12001 attgtccgat tgataattta tatacttgta ctttctttcc atcttgtcgc tgtctttcag
    12061 cccattcact tgcaagtgct gttttacctg ttccggcttc acctaacaag atagcttgcg
    12121 gtgtttccgg tctattcaag atcagtgaca actcatggag ttcgtcatca cgtcccacta
    12181 acttatgttt tggtggtttc attggtgtga gagcatgatt aaattcggtt tgaatattct
    12241 taaaaaactc ggtactattt tccatctgtt tgtgttcact tcctctaaaa taagaataat
    12301 ttacttctag tcagtcaaag ttaggtactt aaatgtcgtc ttcatgtctc caaaagaatc
    12361 tttgttaaag tcagcatttt tgtattgatc aatcaatttt tgtgtatcat tgattgcttt
    12421 aatttcggtc tccattcgac tgtctagttg acgaatactt tcttgcgaat ctttatcgtc
    12481 aggattttgt tgtaaacgtt ccagatactc agcttttgtg gcttcaattt tcttgatgtt
    12541 agtatttgaa gcatttaact gatcttctag cttatttaca acattattct tacttgtaac
    12601 tgctacaact tttgaataat caatatcgcc atctttggta agaaagcttc cttgatagac
    12661 attagttgaa tctgaatatg gatttattct gaaattgata ttatcaggag tattaacagg
    12721 ttttgctttt ttcccaaaag aaattactcc ttcattatta acatcattca tagaatattg
    12781 agaaagtgct tttgtaactg aatctgcttc attcacattg actttggtat catcgtcagc
    12841 tgtatcatca ccagaaatta gtgatacttg gtttgcaata aaaacttgat aagctctttc
    12901 ctctaattta ccttttagga ataagaaagc atccccatca gtacttaaca tcccatagct
    12961 catttcaagc ttcttaggac gatctttttc ttttgttgcc atatataagt tatagttttt
    13021 tccttgcgta gataacaact ttctagcgtt ttgggagtaa ccaagtttta ctactgttac
    13081 atctctattt tgatctgtcc acacatctga aatagtgatt tctgctcctg atcgagcaaa
    13141 ctccaatgaa gaccctatag gtgttgtatt gttcacgaga taataattat agtttcctaa
    13201 ttgataaatg tagctaccca agcctgttaa taaaaaaagc actcctagaa aagttgcaag
    13261 cataatgcgt aatccgtgac gtgttctctt atccttatca ccaagcaacc ctccaataat
    13321 actgtattga tctttggtag atgttgaatt gacgtttttt tccatcagtt tgtctgcccc
    13381 ctttcataaa agagcaaaca atcagacgtt ttttcggtaa ttctaggttc gggattttga
    13441 atcatttcgg tatattcttc cccattaata tttaacacaa aaattatctt cctttcttca
    13501 ttcctttctt ttgctcttta ttttccaaat aatcaatgat ttttgctatt gtaccaagat
    13561 agtaattccc ctcagctttg ttttttcgga ttttgctaac cattggagta ggtacaatct
    13621 cttcatctct caattcactg aaagattttt tacctagata ttttccaata acagatttta
    13681 aaaaacgttc aaaatctttc tcgtaagttg ttttcttgcc ttttagttca tggttcatat
    13741 tgtcaacgac ttttgcggtt tcaataattg ttttagttct cagcttaata atttcatctg
    13801 gaattttcaa tcctcgtaat ttcatcgttg tactaactgg taacccatgc tttactgcat
    13861 cagcaatact aaaacttttt agatcatcta gtaagctctc catatagtta acaaattcat
    13921 gccaattaat agcattcatt gtctcacccc ttcatttttt taaaatgagg ttcgggcgta
    13981 acacatttat gttattataa tatcataata acataaataa atcaatcagc aaatttagat
    14041 atcccttaaa gtatcagcaa ttattcaaca agatatttat tttagctatt tcagtcatca
    14101 taaaagacta attagcaata aaataactaa tattatccat ttatcagacg aaaagaaaaa
    14161 acttatctaa ttactctata ttaactttta acaaatagtt gacttgtcca aaaatgttac
    14221 cttcaatctc acaaagatat taagatgttt cctaccaaaa ctgatatcac cggacttttt
    14281 attctgtgtt gtccaaaagt gttaccttta gtcgatcaac aaattaaaaa aaattgtttt
    14341 tttcttgact tgtccaaaag tgttacccat agttgttaaa atttgtatag attagccatt
    14401 ctttcgaata ttatttagac tgaaacttgc ttacaaaaaa acttcttgca tttattgtcc
    14461 aaaagtgtta cccatacttt tttaaagaag caggttgtat taaaattaca accttcttct
    14521 tctcaatctt cttctaacca attatgcatt gaaatggttg gcaagtttga ttctggctca
    14581 ctaaaagtga atctgagccg atcaactctt cttcctttct ttgcatagat tttttcataa
    14641 tcaaaagttt caaatacctg tattccgttt tcatcaggag ctaaaaattc ttctttcgcc
    14701 tgctctagta ttcttttgtc aatatttgtc attctataac ttgaaggtat acttaatgct
    14761 cttctaaaat cttcaacttt gactacccaa taaccatttc gccactcttt atttctgtat
    14821 tgcatgagat gacgatacaa ttcttttgtg tagctacttc ttagttttgt aaaattatca
    14881 agttcaaaac gagtaaagtt tttgccaatt gagtttaaga taaattcaaa ttcctcattt
    14941 gccttaattg taactgtttc cttctgttta tctatccgga atttttgaaa aagccacagc
    15001 tgttcataga cgtctgaatc ttcaaaacgg taggttaaag tacctagttt gtcactcaaa
    15061 gcttttaaca cagaataaaa actgtccttt tctcttctgt cgtatttgac caaataacga
    15121 aagaggttga aatcaaaagt tacttctgct gttccttgac gtttcatttt tgataaaata
    15181 gcccaaaaca catccatttc aacaggctta aatcctcgca aagctgttgt attcagacca
    15241 ttgttataac gcacaattgc atttgtttgt tctgatacta aatctacatc actatcaata
    15301 atcttttcgg taacttcttg agacattgat tactctccaa tcttcttttt gcgctccttt
    15361 aatcatgtta atctggtact aattaaagga aacaattttt tctgcttgtt acctaaatta
    15421 aatcacaact aaaggtaaca gtcaacaaag atttgttact aatctaattt tctatttttt
    15481 cgccttccaa atcaagaaaa ccgaaggtaa cgtcttatcc tagtgtgata cctcaaatgt
    15541 ccacttttgt tacctttgct gtccaaaagt gttaccctta ctgtccactt ttgttacctt
    15601 tactgtccaa aagtgttacc tttatacccc tttaatactt actctcccaa gagattaagc
    15661 ctcccctaac agatatatta acagatattt aacagatata ttaacagata tttaataaag
    15721 gaggattact cctctcttat ttcaaaatct taaaaataaa aaatcttaaa aaaaactaac
    15781 actatctagg agtttatttt gcttgtgtaa ctttgaataa ttgaaaaaaa ggaaaaggag
    15841 gaagcttcag cttccccttt tatttatatt tataatatat attttaatct ttaaaacttt
    15901 agcaaccttc aaaaaggctt tatatcaatc ttaaatagat tttagggtgg acataaagcg
    15961 atgcgaacat ggacaaaaag cgatgtgaat gtggacaaaa agcgatgcaa acgtggacaa
    16021 aaagcgatgt ggtattccga atatatccaa aaaaagaaaa agtatgtgaa tttatttcta
    16081 aaaactagaa aaatatttgt tttttaattt tggtaatttt tataatttcg tatttttttg
    16141 aaaaggattt ttatattgaa aatgttctaa aatagcgatt tctgctgtct tatcaatgaa
    16201 aattgattaa aaaaataaaa tgtgttttac agagattgag ttatgttata aatttacgat
    16261 acatttctta ttgtatcgta tcgaaaacag gtctatactt attcaatgga atcgtaccag
    16321 ttccaaattt ttaagctcgt accaagctta gaaagaagag gcaatcgtat gaaaataaca
    16381 gaaaagaatg taaacccgaa atttgaacct accgaaagca atctaaaaaa gtttgattta
    16441 actgttactt tatcgaatca acttgtagat agcattgttg aaatggatgc tatgccacaa
    16501 aaaatttatc tttatgctat aggacatctt gaccctaaaa atccgccttt taataatact
    16561 gttaaagtat ctaaaaaggc tttatttgcg ttgatgtctt ctagttcatc ttcttcaaaa
    16621 cattcaagat taaaacaagt tattgaaaaa ttgcatcagc aatctgtcat taaaattcaa
    16681 agaactaaac ctaacggtaa gactgaatac aaagtcatct caccgctaga aattactgaa
    16741 ttcaatgatt tttctgatgc agtatctatt aaatttagta gttcaattat gcctttatta
    16801 acgaacttag aagatcattt tacgcaatat acatttgatc aagtagttaa cttgacaagc
    16861 aagtatgcga tcagtttttt tcaattattc actaaagatt ttaatctgta tgaagcaaat
    16921 agagataact taacatggag tacaaaatca cttgatagat taaaaaatcc tgttttctcc
    16981 attgcagatt tacgaaagaa atttagtatt gagaaaaaat ataaagcttt tcgagacttt
    17041 gaaagacgtg taattaaaga accgattgcc caactgaata aatacactga ttttaaaatt
    17101 gactatgagc ttatcaagaa gggtcatact tatacaaaca taaagttctt gcttacacgt
    17161 accatgtcag ttccggtacc ttataagcaa gaacaaagag accctgctta tttaaaaggc
    17221 gcagaagata aaacagagaa aatgaatcaa tcgtacttga aagctatgaa tagcaaatac
    17281 actaaattac taatcaaaaa ctttttgatc agttctgccg acttatgcga tcttaaactt
    17341 atgagccgac ttcagaataa agtttatccg ctttatgatc gtttatccaa agatagagga
    17401 tttgaatcag ttgtcaatca cctatcttac gttgctactc ataaggagga ttacacaata
    17461 aaaaatactg ttaaatatct cgaaaaatca attacgagtt atttgcctta tgtgaacctt
    17521 tatgattaac aactgaaaaa atgcgtgaag gaaggaaaaa cttttgaaaa aagatgaact
    17581 gacaaagtac aatgaggagt tcttagcaac aattgacatg aaaatggatt taaagtcgta
    17641 tgaactttat caattgctgt tcagttatat ctcacccaca aagctaaaga aaacaggcgt
    17701 agtagattta cctgttaaag cgattattaa ttacatggat gttgatcaaa atcttgaaac
    17761 ggaactaaaa accatagtta acactttgca aagacaagca gtttatgaaa tttcgaatct
    17821 agacaaaaaa tataagacgt atactactgt atctgctatt gatcggattc attgggattt
    17881 agaagagcat agtgtatctt tcagtttttc agaagatgta attcccttaa ttgtctcaat
    17941 caaaaagaag tatccgttct ttgtttttga agacttagca tcttttcaaa aaaaatatag
    18001 catcgtgtta tacaaatatt tggcgatgta ttataaaaaa tatcttatcg ccaaaaataa
    18061 aggagatttt gagaaagctg aaatatataa gaatcccctg attgaaatag ttaaaattcg
    18121 tgagattacg aaaacagaaa atgagtataa aacaatatcg aattttgata gacgtgtttt
    18181 aagggaatca gttgaggaaa ttaatgaaaa atcaatgctg aatattgatt ttgctaaagt
    18241 tagaaaaggc agaaattaca attttgctgt ccagtttaat atttctagtg agtttgatga
    18301 aaaaacttat agagaaaaaa aattaggtta atgcaaaata tatcttactc gtttgaagat
    18361 gcttcagacg tatgctaaga tatatagtgc cttgggagca aggtattaat ctcctttaga
    18421 ggttaattag cttgtgatcg cctatcaatt tttttggtag gcgattcttt tttttgaaac
    18481 aaaaaagcaa aaattatttt ttaattagag aggtgcaatg cgatgaaata ctttttttgt
    18541 gcagtattcg aatggaaagg aaatgaatat gcagttaaat tcccagattt tccagactta
    18601 tatacacatg gtgaaacttt agaagatgct tttgagatgg cgcaagaagt attggaagga
    18661 tacttggtgc ttttagagtt gcaagaaaaa gaaattccat cgcctacgcc tgttcaagag
    18721 ttaaatgcaa gaatcaagcg atctgagaat gttaatttat ttgtcgtaaa agctaatacg
    18781 aaagttgcta aagctcgaaa caagcaaaat tatgatcgaa aatcagtgac tgtggaacac
    18841 tatttaaatg ttttagcggc tgaagagaat attaatctgt cgaaagcttt gaatgatttg
    18901 ttgagagaaa agttgatttg atgtctctca gatgatcata ttaagcaaaa acagcttgtt
    18961 ttaggacg
//
LOCUS       DACGMI010000059        18520 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.061, whole genome shotgun sequence.
ACCESSION   DACGMI010000059 DACGMI010000000
VERSION     DACGMI010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.061"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            115..762
                     /locus_tag="IXT46_002276"
     CDS             115..762
                     /locus_tag="IXT46_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAQ4948175.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            1155..3800
                     /locus_tag="IXT46_002277"
     CDS             1155..3800
                     /locus_tag="IXT46_002277"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAQ4948176.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4110..5423
                     /locus_tag="IXT46_002278"
     CDS             4110..5423
                     /locus_tag="IXT46_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAQ4948177.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5413..6066
                     /locus_tag="IXT46_002279"
     CDS             5413..6066
                     /locus_tag="IXT46_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4948178.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6121..6813
                     /locus_tag="IXT46_002280"
     CDS             6121..6813
                     /locus_tag="IXT46_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAQ4948179.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6963..7163
                     /locus_tag="IXT46_002281"
     CDS             6963..7163
                     /locus_tag="IXT46_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4948180.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7417..9096)
                     /locus_tag="IXT46_002282"
     CDS             complement(7417..9096)
                     /locus_tag="IXT46_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAQ4948181.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9098..9310)
                     /locus_tag="IXT46_002283"
     CDS             complement(9098..9310)
                     /locus_tag="IXT46_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAQ4948182.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9703..11433
                     /gene="efrA"
                     /locus_tag="IXT46_002284"
     CDS             9703..11433
                     /gene="efrA"
                     /locus_tag="IXT46_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAQ4948183.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11430..13190
                     /gene="efrB"
                     /locus_tag="IXT46_002285"
     CDS             11430..13190
                     /gene="efrB"
                     /locus_tag="IXT46_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAQ4948184.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13285..13482
                     /locus_tag="IXT46_002286"
     CDS             13285..13482
                     /locus_tag="IXT46_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948185.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13635..14120
                     /locus_tag="IXT46_002287"
     CDS             13635..14120
                     /locus_tag="IXT46_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAQ4948186.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14224..14817)
                     /gene="clpP"
                     /locus_tag="IXT46_002288"
     CDS             complement(14224..14817)
                     /gene="clpP"
                     /locus_tag="IXT46_002288"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAQ4948187.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            14997..15524
                     /locus_tag="IXT46_002289"
     CDS             14997..15524
                     /locus_tag="IXT46_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAQ4948188.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15615..16352
                     /locus_tag="IXT46_002290"
     CDS             15615..16352
                     /locus_tag="IXT46_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAQ4948189.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16356..17273
                     /gene="miaA"
                     /locus_tag="IXT46_002291"
     CDS             16356..17273
                     /gene="miaA"
                     /locus_tag="IXT46_002291"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAQ4948190.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17275..18504
                     /gene="hflX"
                     /locus_tag="IXT46_002292"
     CDS             17275..18504
                     /gene="hflX"
                     /locus_tag="IXT46_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAQ4948191.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5987 a         3203 c         4024 g         5306 t
ORIGIN      
        1 ttttgaacac cgttttattt gtctcacacc cttttccttc ctacttgtaa ccttgctccc
       61 gtgttagaaa catgttacac taaatatgtg aaattattaa caaggagcgt cgttatgcga
      121 gaaaaaacag atacactgcc aaaagcaact gcgaaaagat tacctttata tttacgctac
      181 ttgaagatgc tggatgactc aggtataagt agaatcaaat caaatgagtt cagcgaaatc
      241 acccaaattc cttctgcaac gatccgcaga gacttctcgc aattaggcga gctaggcaga
      301 agcggatatg gctatgatgt cccttttctt atcgatgtat tcaataatat ccttaatact
      361 aaagaagaaa aacgaatcgc attagtagga tatggaaatc ttggcaaagc attgaaacac
      421 aacaatttta gaagaaatga aaatctaaat atcgtgtgcg tctttgataa tgatccagca
      481 ctgatcaatc gagtaattga tggagaaatg atctatccga ttgatcgttt cgcggagata
      541 gccaaagcaa aaaatgtgac agtagcaatc tctacggtac caagtaaata ttcacaatct
      601 gctattgatg aaattgtcaa aggaaatgta accgctatac ttaattttgc gcctgacaga
      661 gtaactgtcc cagcttatgt caatgttcaa tacattgatt tgacaaccga gttgcagacg
      721 cttatttact ttgatgagaa ttactcagaa gttttttctt aggaaaattt gagtaggctt
      781 attgatcttg cgagaactcg tcgtaattct ttcaaaaatt ttttagtact aaatgaagtg
      841 gttttttcac gaccacttgt tgactaaaaa aaaaaaccat tgtagaatga agcataacgc
      901 tgaacaagag gagtaactgg cacattcatt cttagagaga gaactatctg ctgaaaggtt
      961 ctcaatgaca accagtgaag gtagcttggg agtttctgtc ttgaatggag tagagataga
     1021 cgagtcgtga tcgttaactc acttgagagg caataatgat tgattattgc aatttaggtg
     1081 gtaccgcgta aatcatacgt cctagaatac gaaagtattt taggacgttt tttagtttaa
     1141 aggaggaaaa cagcatgacg gaagaaaata acctatcaac aaaatataat ccgcaagaag
     1201 ttgaagctgg acgttatcag cattggttag aacaagattt gtttaaaccg agcggagata
     1261 aaaaagcaaa accttattca atcgtaatcc cgcccccaaa tgttactgga aaacttcatt
     1321 tagggcatgc ttgggatacg accttgcaag atatgctgat tcgtcaaaag agaatgcaag
     1381 gatatgatac tttatggctg cctggtatgg accatgcagg aatcgcgaca caagcaaaag
     1441 tagaagcgaa gcttagagag caagggattt ctcgttatga tctaggtcgt gaaaagttca
     1501 tcgatcaagt gtgggaatgg aaagaagagt atgcgagcca catccgcgaa cagtgggcta
     1561 aaatgggctt atctttagat tacagtaggg aacgttttac attagatgat ggattatctg
     1621 aagcagtacg taaagttttt gttaccttat acgaaaaagg tttgatttat cgtggtgaat
     1681 atatcatcaa ctgggatcct caagcacgaa cagctctatc tgatatcgaa gttattcata
     1741 aagatatcga aggcgccttt tatcatatga gctatgaact agcagatgga tcaggcgtag
     1801 tagaaattgc gacaacccgt ccagaaacga tgttgggaga tacggcgatt gctgttcatc
     1861 cagaagacga gcgttatcaa gcgctcatcg gcaaaaaagt gattctacct ttagtcaata
     1921 aacaaatccc aatcattgca gatgaatatg tagatatgga attcgggaca ggtgtagtaa
     1981 aaatcactcc agcacatgat ccaaacgact ttgaggtagg taatcgtcat gatcttccac
     2041 gcgtaaatgt tatggatgat gatggtacga tgaatgaact agcaggaaaa tatgctggaa
     2101 tggaacgttt tgctgctcgt aaagcaatcg tgcaagatct gaaagaaatc ggtcgattga
     2161 ttaaaatcga tacgatgatc cacagtgtgg gtcattccga gcggacaggt gtcgttgttg
     2221 aacctcggct gtctactcaa tggtttgtaa aaatggcgcc gttagcgaaa aaagccattg
     2281 ataaccaaga aacagatcaa gcagtggaat tcttccctcc aagattcaat caaacgtttt
     2341 tacgttggat ggaaaatgtc catgattggg taatctcacg acaattatgg tggggacatc
     2401 aaattcctgc atggtatcac aaagaaacag gtgaaatgta tgtagggatg gaagcaccag
     2461 cggatagtga aaactgggta caagatcctg atgttttaga cacttggttt agttcagctt
     2521 tgtggccttt ctcaacaatg ggctggccag atacggaaag cgaagattat aagcgatact
     2581 tccctactag cactttagta accggttatg acatcatttt cttctgggta agcagaatga
     2641 ttttccaaag cttggaattt actggcgaac gtccatttga gaatgtcttg attcatggat
     2701 tgattcgtga cgaacaaggg cggaagatga gtaaatcatt aggtaatgga atcgatccga
     2761 tggaagtaat cgaaaagtat ggagcagatg ctctccgctg gttcttatcg aatggttctg
     2821 caccaggaca agatgtccgc ttcagctatg aaaaaatgga tgcttcttgg aactttatca
     2881 acaaaatctg gaatgcttca cgtttcgtta tcatgaatat cgaaggaatg accgtagaag
     2941 agatcgattt atctggagaa aaatcagtgg ctgaccggtg gatccttact cgtttgaatg
     3001 aaacgatcga acgagtaact gagctatttg atcgttttga atttggtgaa gcaggtcgac
     3061 aactgtataa ctttatctgg gatgattttt gtgactggta catcgaaatg agtaaagaag
     3121 tactttatgg agatgatgct gtttcaaaac aaaccacccg tagcatctta gtccatacac
     3181 ttgatcagat cctacgttta ttgcatccaa tcatgccatt cgttacagaa gaaatatggg
     3241 aacatattcc tcatcaggga aattctctag tagtggcaga atatcctgtt gtacgtccag
     3301 agtttgatga tgaaacagct tctaaaggga tggaagtatt gaaagaattg attcgagccg
     3361 ttcgaaatat tcgttcagaa gtgaatacac cattgtctaa accaattacg ttgctaatta
     3421 aaacaaacga tgctaaaatc gatcaatttt tagttgaaaa tacaagctat atcgaacgct
     3481 tctgtaatcc cgaagagttg acgatatcaa gtgagatcac tgcgccagat ctagcgatgt
     3541 cagctgttct gacaggtgca gaaatcttct tgccgttagc aggattgatc aatattgaag
     3601 aagaaatcaa acgattagaa aaagaactgg aaaagtggac aagcgaagta aaacgtgtcc
     3661 aaggaaaact ttctaatgaa cgttttgttt ctaacgcgcc ggaagaagta gtagaggcag
     3721 agcgtgcaaa agaaaaagat tatttagaga agcaaacggc tgtcaaagaa cgaatcgaaa
     3781 gtttgcgtac tattcaataa gaatagaaaa agagagtgtg aaatcagcta gctattacta
     3841 aaagctagct gattgaacat cgttacagga aagagtttga gcctcactct tagcttcgat
     3901 tcataaggag atgtgacata aattttgtcg catctctttt ttagtctact cttattatgt
     3961 aggagaagga gggaggtgga tcatgtatca agagtcaata aagtagttga taaaatcgtt
     4021 cctctctctg tttcttttct ctttgtcata cttttatttt tcttatgtgt tctatttgtt
     4081 ataataaaag agaaatgggg gaattgttga tgacgattga agaagcaata gaatggatcc
     4141 atagtcgatt accatttggt tcacgtcctg gccttgaccg agtcgaagct ttattagaag
     4201 tggtagggca tccagagaga aaagtaaaaa cgatccatat cgctggaaca aacggaaaag
     4261 gttctactgt agcttatttg agaagcctat tagaagaggc tgggctgaca gtaggtacat
     4321 ttacttcacc ttatatcgaa acgttcaatg aacggatcgc aatcaatggc aaaagcattc
     4381 cagacaatga tttgatccag cttgtaaaaa aatatcagcc actgatcaaa caacttgatc
     4441 aatttgaagc agtagctggt attactgaat tcgagacatt aacagcaatg gcatttgatt
     4501 attttttgat gaagaaagtg gacgtagcga ttatcgaagt tggcttaggc ggcttattgg
     4561 attctaccaa tgtagctgta ccaatgctga cgggaataac aacgattgga cttgatcata
     4621 ccgaaatact tggagataca attgaagaaa tcgctgcaca aaaagctgga atcatcaaac
     4681 aaggcgttcc agtagtaaca ggaaatattg ccccagaagc ttttactgtc atccaacaaa
     4741 cagctaaagc aaaaaatgca ccgctttatg tatacgggga aaattataaa ataaactatc
     4801 tgcatcctga tgagatgtgg ggagaagtat ttgaattttt taatgaaata ggaaagatcc
     4861 ctcaattaac cactccgctt ttagggcaac atcaagctga aaatgcagga gtagccatcg
     4921 aattgtattt tgtttactgt caattggaaa agctgccttt ccgagaaaaa gatgttttga
     4981 agggattgaa gaaatctcga tggccaggaa gaatggagcg tttgagtaac gagccattag
     5041 ttgttttaga tggtgcccat aatacgcatg caatgaaccg gcttgttgag aatttgaaaa
     5101 aagaattcaa aggatatcaa atcaacattt tgttttccgc cttacgaact aaaaatgtta
     5161 gagaaatgct agaacgattg cagcaagtac caaatgtcca tatttatttg acgacctttg
     5221 aacatccaaa agccatcgaa ttaagtgaag tatcagattt agcaagtgag agagtatcaa
     5281 tcgtttcatt gtggcaattc ggattagcag atatattgga aaagatgaca aatgaagacg
     5341 tattagttgt gaccggttca ctttatttca tttcagaagt tcgccattta ttaatacaat
     5401 taggaggaga tcatgaagta taatgcagtg atttttgaca tggatggttt gctgttcgac
     5461 acagagttag tgtattacga agccacacaa gtagtagcag acaagatggg ttttccttat
     5521 gataaagacc tgtatttaaa attcttaggt gtttcagatg aagaagtatg ggcgaattat
     5581 catatgattt tctcggaatt tggcaaaaca agtgtacaaa gattcataga tgattcatac
     5641 caggaaacgc ttgaacgttt ttcgcaagga gcggtacaaa tgaagcccgg tgtgttggaa
     5701 ctcctctctt ttttagaaga acatcagatt cccaaagttg tcgcttccag taaccaacga
     5761 gcagtcattg aacttttatt gaagaagaac aatctgtttg aacgatttga gacgattgtt
     5821 tctgcagaaa atgttcaacg agcaaaacca gacccagaaa ttttcttgtt agctaatcag
     5881 aagctaggta cagcgaagaa agaaacattg attttagaag attcacaaaa tggtatttta
     5941 gcagcttctg cggctgagat cccggtagtc atggtaccag atctgcttcc accatcccaa
     6001 gaattgatca aaaaaacagc tggggttgtt tcttctttac atgaaatccc tgcattgtta
     6061 aaataaaaat ccatctcttt tcgtatctta ttttagataa gatagaaagg agatgttttt
     6121 ttgggaaaac gattgatcaa agaagtacct actagctctt taccaaggga acgtatggaa
     6181 atttatggcg cggaagcttt atcggatcag gagcttttgg caatcttact gcgtaccggt
     6241 caacaccctt atagtgtgat gtcgattgct ggaaatctgt taaaaacgtt tggaggactg
     6301 gcctctttac gacaggctac tttgcatgag ttagaagaga ttcgagggat aggacgcgtg
     6361 aaagcaatcg aaatcaaagc cttgatcgaa ttaggtcgac gaattcagac ggatcatgaa
     6421 agagcggctc caccggttcg taccagctac gaattggccc agcaattgat tctggaaatg
     6481 aaagatcaca aacaagaaca tttggtttgt atttatttgg acacgaagaa tcaagtgatc
     6541 ttaaaaaaaa cagtgttcat cggttcgctg aatcagtcag tcgctcatcc tagagaaatt
     6601 ttccattatg ctgtacgtta ttgtgcagca aggatcgttt tagcgcataa tcatccttct
     6661 ggtaatgtta ttccatcgca gcaggatatg aattttacca aaaggataca aaagtgtgga
     6721 gaaatgatgg ggatcactgt actggaccac ttgatcatcg gacgcaaacg atattttagt
     6781 ttgagagaag aaggaatgat ggaagagaag taagttgctt tcttgcaaaa aaaatgaagc
     6841 aagtgtacaa ttatattgta attttgtttg ggaatagaag ttgaaacatc tgttgcacct
     6901 ctatcgtaca cgagcaatgt tacaatttaa attagtgctt ttggcacgag gaggatatta
     6961 ttatggaaaa cggaacagta aaatggttca acgctgaaaa aggatttgga tttatctcac
     7021 gtgaagatgg aagcgacgta ttcgttcact tctcagctat ccaaggtgac ggattcaaaa
     7081 cattagaaga aggtcaagca gtgactttcg acgttgaaga atcagaccgc ggcccacaag
     7141 ctgcaaacgt tgtaaaagct taattttatc tgtaaatcaa attgatggta gacatcaatt
     7201 tttacgagag aacaaagcga gtaacaaaaa tacctgccac aagagacaat ttctcttgtg
     7261 gcaggtattt ttttgtatga aaaagtaaat aaatttaaga ggctatgaaa gagccacctt
     7321 gtatcaagga ataagaacaa acaaaaatgg cttctcatgt ttttcatttg ttttctctta
     7381 tattcaggac aaggtgctga tttcataacc tcttatttat tcttcatctg gtgtcattac
     7441 cattggcaaa atcattggat gtctttctgt acgttcgaat aagaaaggct gaagcgcgcc
     7501 agtcatcgct tctttcaatt tatattctga acagtcaggt ccattcaaac attctcttaa
     7561 agcgtggaat aagattcgct gagcttcatt gatcatttct cctgattctc gcatgtagac
     7621 aaatccacga gagagaatat ctggaccagc caagatttct tttttcttga tatccactgt
     7681 cgcgacagct aatacaagac cttcttctga aagcaggtga cggtcacgta aaacgacatt
     7741 accaatatca ccgatcccgc taccatcgat atacacatct ccagccacaa aatgcccagc
     7801 aggacgcgca gaatcgctag ttaacgctaa aacatcgcca ttttccatga tgaagcagtt
     7861 ttctgcagga acacctacat cttgtgctag agaagcatgt actttcaaca tgcggaattc
     7921 tccgtggaca ggaataaaat attttggctt catcaaacga agcattaatt tttgttcttc
     7981 ttgtccaccg tgaccggaag tatggatgtt attgattttt ccgtgaatca cttctgcacc
     8041 agcttcagac agcaaattga tcaaatgatt gacacttgtt gtattaccag gaataggtga
     8101 acttgaaaag atcactgtat cgtctggctg gatttggatt tgacggtgag taccattcgc
     8161 gatgcggctc aacgcggcca tcgcttctcc ttgagaacct gtacatagga tcatcgtttc
     8221 attggcaggc aagcgattga tttcgtgtgc atctacaaat gtgccgtctg gaactttgat
     8281 atatcctaaa cgttgaccgt tgacgatggc attttccatg cttcgtccga aaacagcgat
     8341 tttacgacca gttgccacag cggcatctgc tgcttgctgc aaacggaaga tgttagaagc
     8401 aaagctggca aaaatgatac gtccttcgat ttttgaaaag atcttcaaaa tagaatgccc
     8461 aatcgttttt tctgatttag taaatgttgg aatctcagca tttgtactat cagataaaag
     8521 gcacaagact ccttcttccc cgatacgagc cattttatgc aagtttgctg gttcgccaac
     8581 aggagtgaaa tcgaatttga agtctccagt cgctacgata tttccagaag gtgttttcac
     8641 cacgatccct aatgcatctg ggatactatg ggtcgttctg aaaaagctga cagaagtctt
     8701 tctaaaacgg atgatcgtat cttcattgat ctcatggagc tctgcatctc gaagcaagcc
     8761 atgctcatct aatttgtttg tgatcaacgc taatgcgaga ggaccagcat agataggaat
     8821 atttgcttgt ttcagcaagt agggtattcc gccgatgtgg tcttcgtgcc cgtgagtaat
     8881 caccaaggct tttactttgt gtaagttttg tatgatgtag ctgtagtcgg gaatgacata
     8941 gtcaattcca agtaaatcgt cttccgggaa tttgatcccg gcatcaatca aaatgatttc
     9001 atcttggaat tgtaccccat acgtattttt cccgatttca cctaatccac caatagcaaa
     9061 gacgcctgtc tcgttatttt tgatggaaag tttcatatta aaactccact aatgagaaat
     9121 cagcattttc tttttcgtac tctagatgac ttccttctag aagttgaacg aattcaatat
     9181 tgtatggggt attttcttcc acacgttggc gagcgtctac atcgcttttt gcctcaatgt
     9241 aaagagattt tgtttcttcc cgtttagggt tgcgtacttt tgtttcttga taataaactt
     9301 tatagatcat tgttttgtct cctttatctg cgtaaagcag tgatttagct agttgatttt
     9361 tttagacaac acaaaacgag gggacaagcc acctggtttt tcatatgctt tgactagaat
     9421 actggattcg agtcaaagag acaagcctcg tttttgctta tctgttcgga tattttttca
     9481 accgtacctt ctgtataaaa aatatacaac aattaattgt tattctagca taaaacagca
     9541 aataagtata gaaatcaact agattgaaag aaaaaatcaa tgtttatcat cccgctataa
     9601 tcataatgac ttttttatga gagaagtgtt ctattaatag gctcgttgtg ctatcatttt
     9661 tagtaatgaa aatgtaacaa aagattaaaa ggagatgaga aagtgaaact aatgtggcat
     9721 tataccatgc gttataagaa attcttgttt ttcaatttca tatgcgtatt tggttttatt
     9781 ttgattgaat taggacttcc tacgatttta gcacgtatga tcgatgtagg aatccgcaat
     9841 gatgattttg attatgtgaa gcaacaaggg atatttatga tcgttattac tgtaatcggt
     9901 attattttga atatcttgtt aggttatttt ggttcgagga ttacgactaa tatcgtagca
     9961 gatattcgag atgatttgtt cgaaaagatc caaagttatt cgcatcagga atacgaaaat
    10021 ctaggcgtat cttcattgat cactcgtaca acaaacgatg cttatcagat catgttgttc
    10081 ctgcaaaata ttttacgtat cggttttatg gcaccaatga tgttcattgt cagtttgtac
    10141 atggtcatgc gtacaagtgt gacactcagt ttgtatgtag taggtgcatt acctttacta
    10201 ttattggcag tcgtagcgat tgctaaggtg tctgaaccgt tatctaaaaa gcaacaaaaa
    10261 aacttagata aaatcaacag tatcttgcgg gaaaatcttt caggattgcg tgtgattcgt
    10321 gcattcgtca atgaaaagtt tgaagaaaaa cgttttgctg tagtcaatga gaattatgct
    10381 tctagttcaa aaagcttatt ccgtttgatg gctgttgcac aaccgggttt ttatttctta
    10441 tttaatatcg taatggtatt gatcatctgg agcggggcag tgcaaatcga tgcaggcgag
    10501 cttcgtgtag gagatttgat tgcgtttatc gagtatatat tccatgcctt gttctcattc
    10561 atgttatttg ctagtgtgtt catgatgtat ccaagagcag ctgtttcagc tggacgtatc
    10621 caagaagccc tagatgccaa accttcgatt gtagaagatc caaatggtat atctgataca
    10681 aaaactaaag ggtatatcga atttcaaaat gtaacatttg cttatccagg ccattcgcaa
    10741 gagccagtga tacgaaatgt cagttttaca gcctctccag gagagaccgt tgcttttatt
    10801 ggaagtaccg gtagcggaaa atctacgttg atccaattga tccctcgctt ttatgatgtg
    10861 agtgaaggaa agatcttgat cgatggagta gacgtgagag attatcggct aagcaagttg
    10921 cgagataaga ttgggtttat tccgcaaaaa gcgctgctat ttactggaac gattgcagat
    10981 aatttgcgat acgggaaaga agatgctacg caagaagaaa tggaacgtgc agctgagatt
    11041 gctcaagctt cagaattcat ttctcgaaaa ccagatggat ttaatgaaca tttatcagaa
    11101 ggtggttcca atttttcagg tggacaaaaa caacgattgg caatagccag agccatcata
    11161 cgccgtccgg aaatctatat ttttgatgac agcttttctg cattagatta tcaaacggat
    11221 gcgaagttac gtgctcgtct gaaaaaagaa acgacagaat ctactgtatt gatcgtagca
    11281 caacgtgtgg gaacgatcat gcatgcagat aagatcatcg tattaaatga aggagaagtc
    11341 gtcggtatgg ggacgcatcg ggagttgttg gaaaaatgcc cgatttatta tgatattgcc
    11401 gcttctcaat tatcaaagga ggaattagca tgaaaaaaac cttttcttcc ttaaaacgtt
    11461 tagctcgata tatcagaccg tatcgtgaga cttttctttt agtgatccta tttacagttc
    11521 tgacagtggc tttcaacgtg gctttgccat atgttacagg acttcctact acagaaatca
    11581 gccgtaatat tgccaatggc gaatcaatca atttttctta tatattcaaa tgtctcattt
    11641 ggatcacagt tgttggaata gggtattgta tttcgcaatt actttctggt gttttgatga
    11701 caaatgtcgt tcaaagtgcc atgcatgatt tgagaagaga catagaagaa aaaatcaatc
    11761 gtcttccggt ttcatatttc gataaaaacc agcaaggaaa tattttgtct cgtgtgacga
    11821 atgatgtaga tgcagtcagc ggtgctttac aacaagcttt tattggtatc gtaaatgcga
    11881 tattgggaat tacgttggct gcagcaatga tgttttatat ccagccgatg atggcgctga
    11941 tctctatgat catgattcca acatcgatct ggatctcaaa acgagtgatc aatgcttcgc
    12001 agaaatattt tcaaagcatg cagaattctc ttggtgagct aaacggctac gtccaagaaa
    12061 atatgacagg ttttagtgta ttgaaagtat atggacgcga aaaagaaaca ttggaaggat
    12121 tcaaaaaagt taatcacagc ttgaaatact ttgggtttcg tgcagcattc atttctggct
    12181 tgatgatgcc tctagttcaa ttaactgcct atgctactta tattggtatg gctgttctag
    12241 gaagctttta tgttattact ggggcgatcg ttgtcggtca actacaagca ttcatccaat
    12301 atatttggca aatcagtcag ccaatgggga acgtgacaca attgtcttca gttttgcaaa
    12361 gtgcatcagc ggcaacgaaa cgtgtattcg agattttaga tgagccagaa gaaaaagaaa
    12421 acaaagtaga tgcttcactg ccagaaacga ttttaggaga tgtgacattc gatcatgtcg
    12481 attttgcata tgatccgaag aaaccattaa tccaagattt gaattttgaa gtgaaagctg
    12541 gtcaaaccgt agctgtggtc ggtccgaccg gtgccggcaa gacgacattg atcaatctat
    12601 tgatgcgttt ttatgacgta gacaaaggag caataaggat tgatggaatc gacaccaaat
    12661 caatgagtcg cagtgatgtg cgttcgctat ttggtatggt cttgcaagat gcatggcttt
    12721 atcaaggaac gattgcagat aatatccgct tcggaaagct tgatgcgaca gattatgaag
    12781 tagttgatgc tgcgaaaaca gcaaacgtag atcattttat ccgaacgatg ccagatggat
    12841 atgatatggc catcaattct gagggagaca atgtgtcttt aggacaaaaa cagttgctga
    12901 cgattgcccg agcagtggtc tccgatccta aaatcttgat tttagatgaa gcaacaagtt
    12961 cagtagacac ccgtttagaa gcgttgattc aaaaagcaat ggatcgcgtg atggagggac
    13021 ggacaagttt cgtcatcgct caccgtttat cgacaatccg tgatgcagat ctgattctag
    13081 tgatggatca aggtcagatc attgaaaaag gaacgcatga gagtttattg gcacaaggtg
    13141 gattttatga aaaactgtat aacagccaat ttgctgagga agcagaataa gtcatataag
    13201 aataaaacag tttaaaactt attttttgtt ctctattctt gataatggta aagtaaagtt
    13261 atcaagaaaa gtgaggacac ggagatggaa cagtttttaa atgaaaaaat tactgaagcc
    13321 aaaagagaag ttgatcgttt aacgcacgtc tgtcagacga agccttttga ttcagctgat
    13381 ttttttgaaa atgagtttca aatcgaacgc ttggcagcac aaatagaagt gtacgaatta
    13441 attttaaaaa aagtaataga agaaaatata gatgtacaat aaaaacaggt aaaacgtcag
    13501 ttaccagata ctgtaaatag acatctggcc tgagcaggtt ttacctgttt tttttcttat
    13561 gaaataaata tatgctatga tacctttatt caataggatt agtttctaca aaaaatgaaa
    13621 ggagaaaaat aaatatggaa cggtttatag catcaaatgc cacagtgatt ggtgatgtga
    13681 cattgtcaga agatgtgacg atctggtatc aagctgtttt acgcggggac agtaattgga
    13741 taaaaatagg acaaagaacg aatatccaag atggtacaat catccatgtc gatcatgatg
    13801 cacctgtaga tattgcggag aatgtgacgg taggacatca gtgcatgcta catggctgta
    13861 caatcgaaaa aggggcgctg atcgggatgg ggaccacgat attgaatcat gcggttattg
    13921 gtgagaatag tttgattggt gctggatcat tagtaacaga aggaaaagtt attcctccta
    13981 atgtcttggc ttttggtcgc ccagctaaag tgatccgtcc tttgacaaaa gaagaaatac
    14041 aaaaaaacaa agaaaacatc cagcattatg tcgagatagg tcggatgcat gcgcaaggaa
    14101 aattcaagga gcaaagatag gcagtagcat ccataaaata aaaaaggatg gtcagtttga
    14161 gttgaccatc cttttttatt tggtttagat aagagagctt aaaaaagctt cctttgaaac
    14221 agattaattt aatgaagaac tgttttccat gacttcatcg atcaatccat atgcttttgc
    14281 ttgttcagct gtcatatagt tgtcacgatc tgtatctttt tcaatcactt caagcggttg
    14341 tccagtgcgt tcagctaaaa ttttgtttaa gcgttcgcgt gtttgcaaaa tatggcgtgc
    14401 cgcaatttcg atttcagttg cttgcccttg agcgccgcca agaggttgat ggatcatgat
    14461 ctcagcattt ggtaaagcaa atcgtttacc ttttgtacca gctgtcagca agaagcttcc
    14521 cattgaagca gccataccca taacaattgt ttggacatct gctttgacaa agttcattgt
    14581 gtcgtaaata gccatacctg ctgtaactga accaccagga gaattgatat aaagatagat
    14641 atctttttca gaatcttgag cgtctaagaa aagcaattgg gcgatgatcg aattagcaag
    14701 atcatctgtt acttggccgc ttaacatgat gatacggtct ttcaataaac gtgagtagat
    14761 atcgtaagct ctttcacctc gtgaagattg ttcaatgact gtaggaatta aattcataat
    14821 agagttcctc cttgatttcg tttagaaata gtgtaccata atttagtttc taatacctaa
    14881 aatgtagtat acatttttgg tcaaaaaagg tcaaataaaa aacttaggca aattagtcgc
    14941 ataaacccgc tttatggtat gataagcaga gaaacaaaac aaggaggaac aacagattga
    15001 tagttggtat tactggcctt atcggagtgc tgacaggtgc tgtagttgtc tatatcggca
    15061 tgatactgca aatgcgtcac ttggaaaata aagaacagcg tagacgtgaa ttggaattga
    15121 aagtcaaaga aatcgagacg ctgaatcaat taaataaaaa gatcaacgag atcttgcaaa
    15181 aacggacaac gctgatggaa gaatatgtca gctttgatgc atttgatgat tgttatatca
    15241 cgattgacga ttttgcgtat ctccaatcat tttcagcgca aaatagtttt tatctgccaa
    15301 attatatttt agacgagcta tttaagaata tctcccatcg aaaagtgatt ttatctccag
    15361 atgaaacaat gaagattggt ggatatgctt ataaaggcgg acgcgtgatt ttagagaatt
    15421 ttacggatag tctgactgaa atgatcaatg aaaaaaaagc tcagttgaag actatgacgc
    15481 gccagccgat tggtttcttc tcgaaagatg atgtttggag ctgatatttt gaagcattgc
    15541 cgttgcacat gagagcgtgg taatgctttc tttttttctt aatgatacaa tagaactgaa
    15601 cggagtgaag aaagatgtta caaatctatg cccatcgcgg aagcagcggc acccacccag
    15661 aaaatacgct tcctgcattt gcagaagctg tacgagtagg tgcagatggt atcgaactag
    15721 atgtccatct aagcaaagat ggttatttga tcgttatgca cgacgaagaa gtggaccgga
    15781 cgactaacgg taaagggctg attcgagaaa aaacattgga agaactcaaa aaattgaatg
    15841 cagggggcaa attcagcaaa gaatttccag cagctaaagt tcctgaattg agagaagtgt
    15901 taggactgct cctccaaaaa aattaccgag ggatgctaat gattgaaatt aaaactgatc
    15961 agtatgaata tcccggtatc gaagaaaaat tagccgaaac attaaaaagt agagattggc
    16021 cttttcaaca tgcatattgc agctttcatt tggattcttt ggaaaaaatc gcattactgg
    16081 aaccggagat acagctggac ttattgatga gtacttctga taaaaagatc caactagcag
    16141 cagaaacccc ttatatagaa ggagtacatc caaaaaatac ttggttgttc gaacatccag
    16201 tccaggcagc tgattttcca aaagcaattc gtgcatggac gattaacgat gaagaagaaa
    16261 tggccaaatg tcaagaactc aaaatagatg gaataataac tgattttccg gagaaagctc
    16321 ttcggtggaa acaatcaacg aaaagtaggt aaaatatgga aaaagtatta gtgatcgtcg
    16381 gtccgacagc agtcggtaaa acagcgctaa gtgtggaact cgcacaacta tttggaggag
    16441 agatcatcag tggtgattca ttgcaaatct ataaaaatct ggatatcggt acagcaaaaa
    16501 tcaaagaaga agagatgaat aatgttccgc atcatttgat tgatgtgatc gaacctactc
    16561 aacgttactc agccgctgat tttcagcatt caggtcgaca attgattacc gagattgcga
    16621 accgagggca cctacctatc atagctggtg gtacgggtct ctatatccaa tcccttctat
    16681 atgattatca gttaggagcg acagaagaag cgaatcctga gattagaaaa aagtatgaaa
    16741 cgttagctga aacaattggt tcccaagcat tatggaatca gttgaaagaa aaagacccgg
    16801 cagctgctga gaaaatccac tggaacaatc aacgcaaagt gataagagct ctggaagttt
    16861 tagagacgac aggacatagt atcacggcac ctaaagaaga gccaaagcaa ttgtatgatt
    16921 acctcatgat tggattagat acgaagcgta gtattcttta tgaacgaatc aatcaaagag
    16981 tcgatttgat gctagcagaa ggtttagtag cagaagcgcg taaggtgtat gagcttggag
    17041 aagtccaggc cagtcaaggt attggatata aagaattttt cccttatttt gaagggaaag
    17101 aaacattgga agaagcaaca gaacaagtca aactacattc gagaagatac gcgaaacgtc
    17161 agttgacgtg gtttcgtaac cgtttggatg cacagtggtt tgatcttata agtgagccaa
    17221 atcaaaaaag tcagattgag caaacaatca aaaaatggct ggaggcggaa taaaatggaa
    17281 gaaaaagtga tcatcgtagg ggtagaaacc gaagcaaacc agcgttactt ttcagagtca
    17341 atggaagagc tagttcagct gacgaatacc gcatcaggag aagtcgtatt cacaattaca
    17401 caaaagagac cacaagtgga tcggcaaacg attatcggta aagggaaatt acaagaatta
    17461 gttcaacaag cggatgcgca tgaagcggat ttgatcatct ttaatcatga gctaactccg
    17521 agacagagcc aactgattac cgatgctgtt ggtcttccgg taattgatcg cgtgcagctt
    17581 atcttagata tttttgcgat gcgtgctcgt tcgaaagaag ggaagctgca ggttgaactt
    17641 gctcagttag aatacctgct gcctcgttta gtagggcaag ggaaaacatt atctcgtctt
    17701 ggcggtggga tcggaacaag agggccaggt gaaacaaagt tagaaacaga ccgccgacat
    17761 atacggaata aaatttttgc tgttaagaaa gaattgaaag aagtagaagc tcatcgagag
    17821 cgcaatcgcc aaaaaagaaa aaatagcgag atttttcaga ttggacttat tggctacacg
    17881 aatgccggga agtcaactat cttgaatcta ttgacacaag cggatactta ttcgaaagat
    17941 caattgtttg caacgttaga tccattgact aagagatggc gttttgctga aggatttgag
    18001 attactgtaa cggataccgt cgggttcatc caagacctgc ctacgcaact gatcgatgct
    18061 ttccattcta cattagaaga aagtcaaaat atggatcttt tgctacatgt agtcgatgct
    18121 agttctccag atcgtatttt acaggagcag actgtcttaa aattgatgga tgaactgaat
    18181 atgaaagaaa tgccgatact gactgtttac aataaggcag accagatcga cccagcgatg
    18241 ttcacgccta cgctattccc aaatgtattg atttctactc agacgaaaga aggtaagatg
    18301 gcgttgatcg aagcaatcaa acgtcagctg atggaactaa tgacccctta tacactttct
    18361 gtgccaagca acgaaggaca gaaattaagc gagttgagaa gacaaacaat ggttttggac
    18421 gaagcgtaca tggaagaaac aaacgaatat gaagttaaag ggtttgcaaa aaccaattca
    18481 aaatggttaa gaaaaaacca ataaaatttt atttttttaa
//
LOCUS       DACGMI010000060        17531 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.062, whole genome shotgun sequence.
ACCESSION   DACGMI010000060 DACGMI010000000
VERSION     DACGMI010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.062"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(305..661)
                     /locus_tag="IXT46_002293"
     CDS             complement(305..661)
                     /locus_tag="IXT46_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAQ4948192.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(675..1085)
                     /locus_tag="IXT46_002294"
     CDS             complement(675..1085)
                     /locus_tag="IXT46_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAQ4948193.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            complement(1432..3618)
                     /locus_tag="IXT46_002295"
     CDS             complement(1432..3618)
                     /locus_tag="IXT46_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAQ4948194.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            3836..4519
                     /locus_tag="IXT46_002296"
     CDS             3836..4519
                     /locus_tag="IXT46_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAQ4948195.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(4600..5319)
                     /locus_tag="IXT46_002297"
     CDS             complement(4600..5319)
                     /locus_tag="IXT46_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAQ4948196.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTNK"
     gene            complement(5631..5837)
                     /locus_tag="IXT46_002298"
     CDS             complement(5631..5837)
                     /locus_tag="IXT46_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948197.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            6082..6684
                     /locus_tag="IXT46_002299"
     CDS             6082..6684
                     /locus_tag="IXT46_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAQ4948198.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            6825..8105
                     /locus_tag="IXT46_002300"
     CDS             6825..8105
                     /locus_tag="IXT46_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4948199.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIDDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            8118..8846
                     /locus_tag="IXT46_002301"
     CDS             8118..8846
                     /locus_tag="IXT46_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4948200.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(8915..10438)
                     /locus_tag="IXT46_002302"
     CDS             complement(8915..10438)
                     /locus_tag="IXT46_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAQ4948201.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            10690..11871
                     /locus_tag="IXT46_002303"
     CDS             10690..11871
                     /locus_tag="IXT46_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4948202.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(11931..13559)
                     /gene="treC"
                     /locus_tag="IXT46_002304"
     CDS             complement(11931..13559)
                     /gene="treC"
                     /locus_tag="IXT46_002304"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAQ4948203.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGENMSEGNGWNALFFNNHDQPRALNRFVVIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(13956..16667)
                     /locus_tag="IXT46_002305"
     CDS             complement(13956..16667)
                     /locus_tag="IXT46_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAQ4948204.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLPQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(16677..17378)
                     /locus_tag="IXT46_002306"
     CDS             complement(16677..17378)
                     /locus_tag="IXT46_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4948205.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
BASE COUNT         4902 a         3408 c         2968 g         6253 t
ORIGIN      
        1 actcagttat cttatcatgt catttctaac atgtcaacaa ctattttata tgttttttaa
       61 aatactattt tattgctttg ctacttaaaa caacagaaat gaatatatca tgtaaattta
      121 cacatgtcaa tatattttta actctatatc cccacctaga tttgaatttt gaccacataa
      181 attgagcatg tctctatagt agaaaaataa agtcaaaaaa agaacacata acacgcttga
      241 tgctaagtgt tcgactgtta caactgtatg aaatgctcag tgacttgatt aaaacagtta
      301 aagtctattt atttaagata agctgttcca tcaactgctc attgtatcca ataaatagaa
      361 cttcatcgat aataatcaaa ggacgtctga ggagattggt atgttgtgtg cataaaaaaa
      421 tcagttgttt ttttcctaca caggaaaggt caatcgcaat gttgtgaaaa gcctcagacc
      481 aagtcgcaaa tagctgttct gcttgcactt cttcaaaact gcataattct tctgcttctt
      541 ctgtacttag atcgcgttct tctaagtcaa caaattgata aggcaattga tggtgttcta
      601 accattgttt cgccttcaga cttgttacac agtgcgctga tccatagact ttcacttcca
      661 cgaaggctcc ctccctatga atttaagatg ttattgtttt gtaaatagat cagatttctg
      721 gcaacacatc gaatttcacg agggacaaat gaccggatct catcttcatt aaatccgatt
      781 agtattcttt tttcatcaat caaaataggt cgtctcaata atgaaggata ttctttgaat
      841 aagacgatca tttgctttaa agttaattcg ttaaaatcta tgcccagctt ttcgtaaatt
      901 ttcgaccgag tggaaataat atcttgaact cctccttcag tcgctgccaa gatctttttg
      961 atctcacttt ctgttaacgg ttcggcaaaa atattcttct cttcaaattc aagttgattc
     1021 gcttgcaacc atgctcttgc ttttctacag gaagtacagc taggcgaagt atatactttt
     1081 atcattttct cactcatttt taattataat ccaattctac agtaatttct tttaaaatac
     1141 caattattag ctaataatat ataaaaaaaa atcaaaataa ctgattattt acgtttgaat
     1201 aatgagaatt tttctatata ttctctattt tgataatagt attctcattt tcaaaataaa
     1261 taagggaggt gtgacaaaat tcttgtcaca cctccctttt ccgaataaac tgtgttccag
     1321 aaatagcttc ttcgaaaata agctgaaatt tcacaaaaat ttgagaagca attttcgtac
     1381 attccttctt ctttcttgaa actgaccact tctgtcacac cctctcttct atcactttcc
     1441 ttttttcaca cgactcccgg tttctttgat aaatctcgat actttcaatt ttcttgaatt
     1501 tttcatttga ggtacacata gatacagacg atttcttgct ctagtcatcg caacataaaa
     1561 tagtcttcgt tcttcttcta tcgtcgtcac tggttctgct tttatttcat taaagtcgat
     1621 tactttcttt tctgtcgctc cgttataagg caaacttcct tcgttacaac caatcaaaaa
     1681 gacatttcgg taactaagac ctttactttt gtgaatgctc tggatacata gtgcatcaag
     1741 ttttccttgt ctgtaagcaa tcaagcgggt ttttaattct ttagctgtcg cttgggtttc
     1801 ttgcgataag gcttggagtc ttctgaaagt agcatgctgc tttacttctt ctcgtatcca
     1861 ttcttgatca ctctggtcga tttccttagc tatacgtggc agatgaagat agctttgaac
     1921 aagcgaatag atttcttgat gctggtctgt tttacgcaac gcttcctcaa actctcggat
     1981 ttctgcagat ttcgatttta aattggggct tatcgacaaa atataatctg caacggctat
     2041 attttgatat ttaggagaaa agtattgatc gcattcactt tttttcaggt agcagtctgc
     2101 catcagctgc cggagcaatt gctggtaggc ctgatttttc ttttgcagat tcagtgctgt
     2161 ttgccaatga acaatttttt gatagaaatg ttggaaagac ttgataccaa agataccttc
     2221 atatggacta tctgcttcca gtacaaaagg aatattcgtt ttcagcagag attggacaag
     2281 ctgctgcgtt tgtgaagctg atcggtataa tatgattgat tccttatatt tcccattttt
     2341 ttgaataaat gtctgaattt gtttgattag ccactgactt tctgctttag tatcagaaaa
     2401 caaataggct tccataacac ctgcttcttt ttgtgctgga atcatcgcct ttggtatccg
     2461 atcattttta ttatagctga tcaatctatt tgctccttgg acaatagctg cccgagaacg
     2521 ataattagtc aataagaaaa gagttttggt aggatattct ttttcaaagt tcttgatgta
     2581 tgctggctct gatcctctga atccatagat actctgatca tcatctccaa caacaatcaa
     2641 cttgatcctg ttttcctttg tcatccgttt cacgatttcc cattgaagtg gattagtatc
     2701 ttgaaattca tcaatgaata gataatcata tttttggccg atataatgct ggatctcctc
     2761 attctccaaa gcgcttttca gattttggag tacatcattg aactctagca attgctggct
     2821 tcttttttgt tcttggagtt ccgtgagcaa tccatacagt cgttctgata tcggctgtcg
     2881 tgcattctta tcaatggaat catatttttc tttaactaac tgaaccattt cttctactga
     2941 aaggttcata ttctgccaat agtctaaccg agaagcaatc gttttttctc catattgatc
     3001 aaatatataa agattatatt tacgtatcag ctgttgcaaa acagcattca ctttttgtgc
     3061 agtatccttt gaaaagtctc cttgtattcc ttgcattgct acttcaggaa attttcgaca
     3121 aatttcattg tatatcctaa aaaagatact atggaatgtt ccgatatgga cagcggtttt
     3181 tctctggctg aaattatcta ctcgtttttt tagttcattt gcagcgttcc ttgtaaaagt
     3241 gatcattagt atgcgttctt cgtctacttg tttttgcgtc atcagataaa cagcttttgc
     3301 acagattgtt tgcgttttgc cgctcccagc tcctgctatg attcgaagat gtttcttcat
     3361 atcatatgtg atagctgctt tttgttcttg attgaagcga ttataggaac gtttctccat
     3421 cattttaaag aaagagctgt ttccttcact ttcttttact tgtacttctt cctcaataag
     3481 tccgggtgct tcgccataag ccgcttcata ggtagcaatg atttcttctt gtagccgaaa
     3541 gacttgttga agctttttat acttgttctc ccagcgtttc aattcttttt gtaatcggag
     3601 aatttctttt tcattcaact gattgatttc cttcccatct ttcttctttg aatttgttta
     3661 tttcaagttg gttatttaaa gtttcgttgt ctattttttc tttatactaa cagacctttc
     3721 taaaaatgaa aatgggaagc gatatgattt tagttttctg aaaatttttc ctttttttca
     3781 atcgtttatg ctaagataag gaagacaaaa atattcataa aaggtgatga aaaaaatgca
     3841 gacttccttt cacgaggggc gtacaatagg acttttgctg acatttatcg gaggagccat
     3901 ggacagttat acttatatcc aatatggtgc ttttgcctct gctcaaactg gcaatatcat
     3961 tctatcgatc atccaagcat ttgacggaga atggctaagt gttggtaaaa aagtattgtc
     4021 tacccttttc tttttcttag ggattcttct aacaaagtat ctaattgatt attttagaaa
     4081 aaaagaaaaa catttctggc gcttgtttgt tctatattat gaagcagtga tttttttctt
     4141 tgttagtttg acacccgtcc atgagcatcc cgcattagta acgattttga ttgcttttac
     4201 tgcatcgatc cagtgggtag cttttgataa aatcaacggg cgtgcctaca ctaatttatt
     4261 tacaactgga aatttaaaag gggtagcaac gaacttatat gattattgta tttctaaaga
     4321 aaaagcagat tttgatcgat ttttccacta tctaagtgtc gttcttgcct ttatcgcagg
     4381 agctattgtc cttgttttct gtcatcatct gtttggcgcc cattcgattt tgatcgtttc
     4441 cattttattt ttgatcatgg ccctcactca gacatttcat ttatggcaat tttatcatac
     4501 gaatcggttc actatttgat ctcaatgaat caaaaaaact aagcaagatg ctgctcacag
     4561 agaaatatct gcgagtgagc aatttgctta gtttttatat tatttatttg taaagattcc
     4621 ctttgctttc gggttatttg tagtgtagcg gatcgactgg gcatctgcct cttctgtcat
     4681 tttctttgcc cgcatcttga tttcttgtac gatttgttct ccacatgccg gatcggctac
     4741 gaaatcatat ttgtccccat cgatcactat tttgggacat atatcaaact gttcatacca
     4801 ctcttcgtat cgtcgattga gttctttata gtaggaatag agttcaggat cttgttctag
     4861 ctgttcatat tcccggcctc tttttttgat tctcgctaac atagtttcaa aggatacacg
     4921 aatataaacc agtagatctg gtttcttttg tggcgaaatt tcttctaact ccttcagcat
     4981 cgtttctaaa agaccttcat actgctttac ttctacttca gaaacacgcc ctaaatctgc
     5041 attcaaatga aacagcatac tatcttcgta gatggagcgg tctagtacgt tgtcatcatg
     5101 gctgaaagca tctttgattg ccaaaaagcg tttgttcaaa aagaaaatct gtaataaaaa
     5161 agtatacttt tctggattag aataaaatag cggcaatact tcattatctt ccacgttctc
     5221 ataaaaaggt tttgtttcta aatcttgggc aagcatttca gttagtgtgc ttttccctgc
     5281 accgatcgtt cctgcaacaa tgatcacaat tatcggcatc cttcctgtaa taaaatctgt
     5341 tcttcatttt actacttcat ttatagaaat aaaagccttg actttatctg ctccttaaaa
     5401 gctacttctc taaaagtagc caaaagtaac tcctattcat gaaaataaag gctgtgacaa
     5461 aagtcttgtc gcagcccttt tttcaaataa acagtattct cctgccaaca cctcggtcac
     5521 aaggcaatat tcataaaaca tgaaaagctg ttttttaaca ttattccttg taactcagag
     5581 ctaaacggga gactcacaac ctctttatgc tctcaacatt ttatctgttt ttattcttct
     5641 attgtacttg atttgcgtac aactaactgc cagtgcagat tatgagcggt atcattgtct
     5701 tctactgcgc atttcatgac acgtatcatc acactatttt catagatttt ttctattttt
     5761 ccttttattg gtgattcaaa taaatcagat ttaaatgcat atgtttcgcc gacttcaaac
     5821 aattgttcat tttccataag aatccctcca tcacctttta taaggtcagt aattttttaa
     5881 cataaatcac tcgaaaaagc acaaacttgt cataaaaagt acttttcgta tcaaaactgt
     5941 cacttttttt ggtaaggttc ttggaaaacg aagatttttt taggagatca tgacggtttt
     6001 gatgtcaaaa ccacttttta tgaaacaaaa gacgtttttt atttttttta gcataaaatt
     6061 tgtggtggag gtacgtatga gatgaaagat aaagttgtga acaaattatt agaagcctta
     6121 ttcagcggag acaaatcgga agaagatatg gtgtatgtcc aagtaaaatt tgccttagaa
     6181 gttttattga ataatcttgg aaaactagcg gtcgttctag tcttttctct ggtgacaggc
     6241 tcatgggcgg aaacaggaat cacctttctt tcttatatct gcatccgcag atatgcttat
     6301 ggattgcatt ccgactctga attcgtttgt ctgctgtgga cactacttta tttatggggc
     6361 gttcccttgg tgatgaaaca tctgcaattg actatctcct tcccaatgat ggtctttttg
     6421 ttaatcagct gctttttgtt actgcttcgc tatggatcaa gaggtacagc aatcaatccc
     6481 attgaacccg agaaacgtcc cccattatta aagaaggcga tcagcatgtt tctaattttt
     6541 tctctcatta ctttattttt ctcagcttct tacttttcta cctatttgct acttgggatt
     6601 gttttagaaa tagctacgtt gcttcctatt acaaactact tgatgaattt tggaggaatc
     6661 tttcatgaaa aaaacaatca ttaaacaatt aactaactta tctgactttt ttgtatctgg
     6721 ctgctgcttt ggtatgagtt ctgaattcaa aatccctgaa aaattaaaaa aataatacgc
     6781 taattgtgct ataatttggt aaaaatcaat gggagctgta ctttatgttt ttatggtcca
     6841 tagcgttgca atatttgatt tacacaattt gtatcttatt gattgaccat cacatccgat
     6901 acaaatatct gtttgcggga gtcattctga tttcttgtat tttgattgga tgggtctatt
     6961 cgattttagg gatttttact gctctaattg ctataggaat gctgatgctt acttttttct
     7021 tcttttcgac ttcgcgtcaa caattggttt acgcgcttcc ttttgggtta ttgacgtcgc
     7081 ttttaggaga tcacttaaca agcatcgacg atttttttgt tttgaaatct tcggttattg
     7141 aaccaggaga ttcattgcag tattttcaca ttgtcttatc cgctttttta tctgctttat
     7201 tagctttttg tttaaaaaaa tcgttagaga cttggtttca cactgtggac cgccgtatga
     7261 tcggtacgat cgggacattg atattattta catactatat cattattttt tatacccgtt
     7321 tttctggtga aacacctgat gtcttagctt tgaatacgag ttttttcatt ctatatctgt
     7381 gtgttggcct gatcatcttg gtttattatt ggaaaatctc taataagaaa ttagctgatc
     7441 agttattaga gcaacaagtc aggatgcaac aggattatat caaagatcta gaaaaaaact
     7501 atcaagactt gagagaattc aaacatgatt accaaaatct gcttttttct cttcacagct
     7561 atatttcaga aggcgactta gaaggattac ggtcttatta tgatcaaacg atattaccta
     7621 cacgccagat gatgaacctt tttccggcca atctaagtat gttggataat atgaaagttc
     7681 ctgagatccg tagtttactg tcattaaaac tcatgatggc acaggaaaaa gggttgatcg
     7741 tccagcttca ttttcctgag ccaatcgaac tggatacgaa acatacggta aaccttgtac
     7801 gtatgcttgg tattatcttg gacaatgcga ttgaaggagc tagtgctgca aagaagaaaa
     7861 aaatcgaatt gaccatactc aagaagaatc attccgtgat gattcgtgtg atcaatacaa
     7921 caacaaatac attaccgtta aaccagttga aacaaaaagg gttctcaaca aaaacaaatc
     7981 caaaaaacga aggccttggc ttgtttatct tggatgaatt gacaaagacc aatccttatc
     8041 ttttccttga aacatcaatt gaaaaccagc gtttttctca aacgatttat atacaaataa
     8101 aataaaggag taatgatatg attcccattt atatttgtga agacgatcca aaacaattag
     8161 aagttttatc aacggtgatc aaaaatagaa tcatgattga aaacttagac agttatgtcc
     8221 atatttctac ctctgatccg gaagaacttc tcaatgcagc caagatcaga acttcttctt
     8281 ttggtattta ctttttagat atcgaactag aagacagtga aatggatggt gtagcgatcg
     8341 gtaaattgat ccgtgaatta gatcctttag gaaaaataat ctatgtgact tcccatacgg
     8401 aaatgtcgat gaaaatctta aaaagcaaca tcgaaccgac tgattatatc gtcaaagaag
     8461 atctttatga tttaaaagaa aatgtcgagc atatcctgag caaaattttc gaagattttc
     8521 aaatgtccca aatccaaaaa gatatcttca aaatagagtt taatgatgag atcaaatttt
     8581 taccgatcaa agacatccaa tatttttcta cttcgctagg agcgccacat aaactggaag
     8641 tccatttgac tcatgcccaa ttacaattct atgagaagat caaagaaatc gagaaaatgc
     8701 atcggaattt tatccgttgt cataaatcct atgttatcaa tacacaaaat gtgcggtcga
     8761 ttaataaaaa aaccagagaa gtcacgttgg caaacggcga gaccatccca gcctctatcc
     8821 gtggattaaa gaaattgatt tcataaaaag aaccgaatag tttggaccga ctaaatgacc
     8881 agccgatcca aacccttcgg ttcttttttg cctatcagtg caaaagcatt tcctgtgcaa
     8941 tttcacgtcc atccattgta tctggataaa atgttggcca attctccatt tctttcagca
     9001 atacttcttg actttcattt cctgcatata aatgaaaatg ttcggagtca gccggtgcaa
     9061 tcgtgtgatc actgaattga atatatctaa aagcgccact ttccttatct tctgcttcga
     9121 atagatacct tacgccacgg tttcctgcct cgtaggtcaa gatttctttc cctacataac
     9181 gataatttga acgtttcgtt gttccatcct taaacgtaaa tgccatctct ttctcactga
     9241 tcttgattga agcaatatct gtttgatagc ccttcgtata atattcttta tattcttgtg
     9301 ctgtcttatc ctgattcaat ttttctttat attcaaaaac aggatcaaaa gtcccatctt
     9361 ctacatacgt atctactgtt tgccaagttc ctgcccaatc tgaaagagag cgatcttgta
     9421 catcctcgtc ttcaaaataa ccgttgtaga cgctcttttc ttttttgggg gtcaaagtat
     9481 cttctagcgg gttttctgtc tctgtcgttt ttttcaacgc ttcgaggttt gcttccatga
     9541 tagaaagata gttttctcca ttttctattt gttcattcgt caatccttcc aaaggattca
     9601 atacttctaa agatacacct gcttcgtttg ctaacgttct ggcaatacta tctttggcgt
     9661 tttcttcaaa ataaatatag ttgattccat gttctttaac aaagtgtttc agttcagcaa
     9721 ttctcgccgc agacggttct tcactagaag aaagaccagc aatcgatact tgattcaatc
     9781 catattctaa cgctagatag ttgaatgcag catgttgcgt gacaaaagat ctttgttttg
     9841 cttgcttaaa ggtttcttga taaagctgat ggagtgcttg aagtttctcg gtataggctg
     9901 ctgcattttt tgtccatact tcctgttttt ctgggtaagc ttcaatcagc tgatcacgta
     9961 tgtttgctac ctgcttgatt gctaaacttg gagctagcca tacatgtggg tctagctcat
    10021 gtgtatggcc ttcttccccg tgttcatggt catgatcatg tccttcttca cttcccggaa
    10081 gtaaaagcat accttctgtc gcttttatcg tatggacatt gccttcttgt aatgtttttt
    10141 ggattgcggg gacccatgtt tccatgtttt catcattata aacaaagata tctgtatctt
    10201 ggatctttgc catgtcttta gcagaaggtt cataatcgtg ggaatcagtc cctgctggaa
    10261 tcaataactc tacttctcct tcatccccga cgattgcttt tgtaaaatca tacatgggat
    10321 aaaaggtcgt catcacgctc aatttttctt tactgtcctc ggctttccca cttgccccgc
    10381 aagcagttaa catacctgct aaaaccagca tggccaatat acctatcaat cgtttcattt
    10441 atgacactcc tcttctcatc ttctttcatt tgaatgttcc gattcgcttt tcgcaaaccg
    10501 taatagttac gttttagcaa caggatttaa tttatcatat ggttaaaaga actgtcaagc
    10561 gttttcttat tttaattgat gagaaagttt atatgaatga ttgacgatat ttttgcaatc
    10621 aacctctatc attttccttt tatacccgct tttgtctata atgaagttat agataaagga
    10681 ggaaaaagag tgaaaaaaga aacagataca acgaatcgtt tgatccgctt tttaggagga
    10741 aaaacctctt actatgtttt aggaatagtt atcttacttg cgctgatcat ttattttttc
    10801 catcagatct cgtttatatt caagcctgtc ggaatcatta tcgctactat cttgccccca
    10861 ttattgtttg cactgatctt gtattatctt ttggaaccag tcatcaaacg tttgagcaag
    10921 cacctttcga ggaacttgtc agtcattatc gtttatgtga ttattttatt tttattgggg
    10981 cttggaagca tatggcttat tccttttctt gaagaacagg caaagacatt gatcagtagt
    11041 ttgccagatt tgtttcaaga ttttcaagag agtctccgac aatttttgga gaaaacacct
    11101 tttgccgatt catttaatca attttttgct tctattgacg acgtgacgtc tgatatagct
    11161 ggatttattg gaaattattg ggaaagtggc gcacaacgga tcagcaacat tttttcaact
    11221 gttacagcta tttttattac tttatttact ggtccaattg tcgctttttt ccttttgaga
    11281 gatcctcaaa aattttatca gtcagtttta gcgattgtcc caccagcatt tcgtacagat
    11341 tttaaaaatt tgacaaagat tgctaatcaa caattgggtt catttctaaa ggggcaaatc
    11401 attgcttcat ttatccttgg agcagtctac tgggtttgtt tcttactgat cggattagaa
    11461 tttgctagtg ttttagctat ttctgctggg ttgttatgta tcattccata tattgggccg
    11521 tttatcgcct tctttccagg tttgatcatt gcattccaag actctacttt tatggctgtc
    11581 aaatttgtca ttgtctggtt tgccgtacaa cttctccacg gtgacttggt gattcctcga
    11641 gtaatgggtg atcgtttaca gatccatccg attacgatct taatcgtttt acttgtcatg
    11701 ggtgatctaa tgggaattgt gggcgttatt tttggtattc ctatctatac gttagtcaaa
    11761 ttactcgtta cttttatttt ccgtaaattc aaacaacgct acaataaatt ttatggcgat
    11821 aaaggagagt atgaaaactc ttcattttct gaagaagatt attttaaata aaacacaaaa
    11881 cgtcgatctt acgagaatag ctcgtaggaa cgacgttttg tgtttttgtt ttaatttttc
    11941 agcaaagcaa ttgcctggta tggttttagc tccagacttt gatgaagaac agtatcggaa
    12001 taattatcga taagaatatt ggcttctgtg aatccttctg ggatggcgat ccttgtatct
    12061 ttatcataga aatttgttaa tacaagcagc tgctgtcctt caaattggcg aagaaagcca
    12121 taaacttccg gatgatttgc ttcataagca tgataatctc cttgtgcaac gattggatat
    12181 gtttttctca gccgaatcaa tttcttgtaa taggacaaaa tagaatcttc agaagatagt
    12241 tctttttcta cattaatctc ttctagcttg cctccaactt ttaaccaagg tttccctgta
    12301 gtaaatcctg cttgttctgt gtctgaccat tgcatgggtg ttcgagagtt atcgcgagat
    12361 tttgctttga tccgacgaaa cgcttctttt tctgtgaatc cttgttcaag gagtaactta
    12421 taagcattca aactttctac gtcaatatag tcggaaatcg atgaatagtc tgggtcgatc
    12481 atgccgattt cttctcccat ataaatatag ggcgtcccac ggttcaaatg gatcatggtt
    12541 gctagcatct ctgctccttg ttttcgatac tgatcgataa ctacaaatcg attgagcgca
    12601 cgtggctgat catgattatt aaaaaataga gcattccagc cgttaccctc actcatattt
    12661 tctccccatg tatgaaatag tcgctttaat tctgcaaaat caaatggagg agtagaccat
    12721 ttattcccat tttcataatc gactttcaaa tgatggaaat taaagaccat tgataattct
    12781 tctctactag gttctgtata caagatacaa ttttcgatcg tcgtagagct catttcaccg
    12841 actgtgatga tagtggaatc cgtcccaaac gttgcttggt tcaattcttt tagatacgta
    12901 tgggtgattg gtttgtccgt atattcaggt ttgccatcat tttctttatt atttttcaat
    12961 tgttcgtctt taccgataac attgataaca tcgaaacgga atccttttac ccctttttcc
    13021 atccaaaaac gaacaacttt gaatagttcc tctcttactg cttggttccg ccagttcaag
    13081 tcagcttgtg tccgatcata taagtgcaaa taatatttcc ccgtatctcc aaatggcgac
    13141 caagcacttc caccaaattt tgatacccaa tccgttggct cttctcttaa aatgaagaag
    13201 tcctgataat gctggtcccc tgctagtgct tttttgaacc attcatgttc tgtcgaaacg
    13261 tgattcagca ccatatcgag catgatttct atccggtatt tctttgcttc ggctattagc
    13321 tgttcgaatt cctccatcgt accaaagata ggatcgatgg ctgtgtaatc agagatatca
    13381 taaccgttgt ctttttgagg gcttggataa atagggttta gccaaatcat gtcgatgcct
    13441 agatcattca gatacgggag tttttctttg attcctttta aatctccaat tccatcacca
    13501 ttactgtctt tgtaagattt gggatagatt tggtaaatga ctttgtcttt aaatgtcatg
    13561 gatatttacc tccattcaac tgatttatta cctaccacag cttatatata caagttatca
    13621 tttattatta taactgaaca gaaagcgttt gtaaaattta tctttataca ttctaagagg
    13681 tctgttgccc aataaaaaac aagagatcag acatgtattt gtctatcctc ttgtttaaaa
    13741 tagcaaaata ttcttgtttc ttctataaat ggtgttcaaa agcttttatc tacggcaatc
    13801 agtcttctca aatgtaaaac atgaggagct aattttattt gagtattctt tttgctcgat
    13861 gcaggacggc ttttttacaa cctctgattc atggtgttca attagcagct gaccctcgtt
    13921 attagctcaa aacgctgatt tcacaacctc tgtttttatt cattcgattt caacgcatca
    13981 atcatatcga tatgctttaa tttgaaatgg gtaacaatca tcacaataac cgtaaatacg
    14041 atagttaatc ctgctgataa gacataagcc caccatgtga tcactaatgg aaagatgaca
    14101 ttctccatag acgcttgttg caagatgaag tcagtcaata tatatcctac accaaatcct
    14161 ccgatgattc ctaaaagagt aaagatgata ttttctcgaa caatgtacat cgtgacttct
    14221 ttatcaaaaa atccaaggac ttttattgta gataattcgc gtacacgctc ggaaatattg
    14281 atattagtta gattatacaa gacgataaaa gccagcagtc ctgataatac gacaaagatt
    14341 aagacaaccg agtctaagtt cgccattgat tcttcttgcg tttcgatttg tttggacatg
    14401 aaagacgtat ttgtcacagc gtctgtggca agcagtttct cggaaagcat ttcttcttct
    14461 tttgttgtca tcttatctgt acgcagcaaa aatgcattat ccatcatcga ttgatcagta
    14521 actgaagcat aatattcagg ggacatataa ataaagctac ctagatagtt tttcacgatt
    14581 tcttttactt cgactttcca ttctttttga tcttcatcat aaagcgaaat atgatctcct
    14641 gtagataagt caaatagttc tgctactttt tgcgtaatag cgattcctgt tttaggcaag
    14701 gagcgtgggt tctcttcaag atcagttaaa tggataaaac gatccaaatc agctgtttta
    14761 cttggtacga tcactgtcag actttgcgaa gcatgtcctt tttttctcaa ttctacggtt
    14821 tgagtatgaa tagctaggat ctcatttact ttttcttgct tctgcagcat atccgctgct
    14881 ttttgacgac tatcttccgt ggatgaatcc aatgtaacga ttgcttgata gtcaatgatc
    14941 ggtccaaatt gtttggctga aacagaactt agagaatctt tcaatcccac gcctgcaacc
    15001 atcagcccgg cacatccagc aattccgata atcgccataa gcattcttga cttatatcgg
    15061 aagagatttc ggtaactgat tttttgatta aagctaaggc gtgaccacag cggagtgatg
    15121 tattcaagaa aaatgcgttt ccctggcttc ggtgctttcg gttgaagcaa tgcagcaggc
    15181 cgttctctta aatctttgaa taaaacgatc attgcagcgc caaatgcggc aatgaagaat
    15241 gcggcagctg cttgtaaaat cggcggccag tcataaaaaa taagcgcact cccaatatca
    15301 taccgctcgt tagacagctc aaaaatgatc cttggcaaaa gattcgttcc taatatcgtt
    15361 cctaaaacaa tacctatccc tgaggctaga cttgcataga ttgcatattt ttttgcgatt
    15421 tcaactttcg tataacctaa cgcctttaat gtcccgattt ccctgcggtt ttcttctacc
    15481 atacgtgtca ttgtcgtaaa ggtgatcaat gcggcaataa agaaaaagaa aacaggaaaa
    15541 acattggcaa tcgcagcgat acgatcagac agatcaccaa attcttgaaa accgacattt
    15601 tctgaacgtt cattgtatag gtatgatggt ttagttaaat tttcaatttt ttctgcattt
    15661 cgattcaatt cttcctctgc agaggccagt tcacgttctt tctcaactaa ttgcctttct
    15721 tgttcagcaa gttgagcttc ttgttgaggt aatgtttgaa cagcgattgt tcgttgcgct
    15781 tcaggaagct gctggatagt tgctgactgt tgcgctaact gttttttagc atcttctaac
    15841 cgtgttcttg cttgcgttgt ttgtgctttg ccatccgcta ttttttgctg tgccggttct
    15901 aattcttcgt tggccgattt tttcagctct tctaagcgtt cttcgggtcg atcttgtaaa
    15961 tacttttctg ccttttcttg attttgctcc attttatctt tgtaagcttt gctgtacgta
    16021 ttcaaattct ttacgtttgt aaaatcaaga tataagacag aataaatatc tgttttaaaa
    16081 acggattcag gtaaatagac aaaataatcg acgctaccat ttccgacgtt cgcgtatcct
    16141 ctctccaaat tgttgatgaa caatggagaa cggacaaagc ccgtgatggt atactctttt
    16201 tctttcaatt catctgaatc aatctgataa atatcaccga ttttataccc ttcatcttcc
    16261 gctttttcat ccaatacaag ctggtttggt ttttccggga gttttccatc agttaattgt
    16321 agcttgttct gcttgttatt tttgttataa gaaaatattt gaatcacttc gtttttgcca
    16381 gtattggaat aatagatctg ttttcctgtt tctacttttg catctgggat cttttctgct
    16441 tgagcaatat ctttttgtgt caagccacca gtagaaacga tttgcaaatc agaaagtcct
    16501 gctgtaccaa catagtgatc catcgttttt tgcatgacag gtccagcagt tttgacacct
    16561 acaaataaaa gtgttcctag catgacaata aggatgattg caatgaatcg tcctttagat
    16621 tgccgaattt cgcgaaaacc tgctttaaga tatgttcttg ttttcataaa atccccctac
    16681 catacaatct catcaatgga tgaaggatga tcatttaatt caacagacct tactttagca
    16741 tcattaatgt gaatgactct atcagcgatg ggcgctaaag cagaattatg tgtaatgatc
    16801 aaaacggtat tgccgtgttg tctgctagcg ttttgcaata atttcaatac ttgcttgccc
    16861 gtttcaaaat ccagcgcgcc tgtcggttca tcacataaaa gaagtttggg atttttagct
    16921 agtgcacgag caattgaaac cctctgctgt tcgcctcctg ataattggga cggaaagtta
    16981 ttcaatcgat gagctaggcc cacttgcctc aatacctcta caggatcaag cgcatcagga
    17041 gaaacttccg ttgccaattc cacattttct tttgctgtta gattaggaac gagattgtag
    17101 aattggaaaa cgaaccctac atctgttcgt cggtaagcag taagctgttt atctgaaaat
    17161 tgcgcaatat ctgtgtcatc aataatgatc tgaccttcat caggtgtatc catcccacct
    17221 aaaatattaa gaatcgttga ctttcctgct ccacttggac caagtataat cactaattcg
    17281 cctttttcaa ttgaaaaaga aatatcgtca tttgctgtaa tggtcgtttc tcccattttg
    17341 tatcgtttgt attcattttt tacttcgaca tacttcactc tgattcctcc attttcacga
    17401 tatttctcgc tatatctatg catcgaatgc gttttctcac acttatttat tttaccactg
    17461 aatttctcta gactaaagaa aggaatcctt taatttagtt gacaaataaa cgatttatga
    17521 tttacttaca t
//
LOCUS       DACGMI010000061        16884 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.063, whole genome shotgun sequence.
ACCESSION   DACGMI010000061 DACGMI010000000
VERSION     DACGMI010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.063"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(258..1763)
                     /locus_tag="IXT46_002307"
     CDS             complement(258..1763)
                     /locus_tag="IXT46_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4948206.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1760..2446)
                     /locus_tag="IXT46_002308"
     CDS             complement(1760..2446)
                     /locus_tag="IXT46_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4948207.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2639..4060)
                     /gene="gndA"
                     /locus_tag="IXT46_002309"
     CDS             complement(2639..4060)
                     /gene="gndA"
                     /locus_tag="IXT46_002309"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAQ4948208.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            complement(4230..4409)
                     /gene="rpmF"
                     /locus_tag="IXT46_002310"
     CDS             complement(4230..4409)
                     /gene="rpmF"
                     /locus_tag="IXT46_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAQ4948209.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(4467..5036)
                     /locus_tag="IXT46_002311"
     CDS             complement(4467..5036)
                     /locus_tag="IXT46_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAQ4948210.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            5222..6124
                     /locus_tag="IXT46_002312"
     CDS             5222..6124
                     /locus_tag="IXT46_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4948211.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(6159..7943)
                     /gene="pyk"
                     /locus_tag="IXT46_002313"
     CDS             complement(6159..7943)
                     /gene="pyk"
                     /locus_tag="IXT46_002313"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAQ4948212.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(8017..8979)
                     /gene="pfkA"
                     /locus_tag="IXT46_002314"
     CDS             complement(8017..8979)
                     /gene="pfkA"
                     /locus_tag="IXT46_002314"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAQ4948213.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(9147..12461)
                     /gene="dnaE"
                     /locus_tag="IXT46_002315"
     CDS             complement(9147..12461)
                     /gene="dnaE"
                     /locus_tag="IXT46_002315"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAQ4948214.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            12692..12877
                     /locus_tag="IXT46_002316"
     CDS             12692..12877
                     /locus_tag="IXT46_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAQ4948215.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(12939..14135)
                     /locus_tag="IXT46_002317"
     CDS             complement(12939..14135)
                     /locus_tag="IXT46_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4948216.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(14305..15741)
                     /locus_tag="IXT46_002318"
     CDS             complement(14305..15741)
                     /locus_tag="IXT46_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAQ4948217.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            16034..16843
                     /locus_tag="IXT46_002319"
     CDS             16034..16843
                     /locus_tag="IXT46_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4948218.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         4955 a         3539 c         2948 g         5442 t
ORIGIN      
        1 aaataataat atagcaatct ctttataaaa ttgcaataga aaattcccta tttttattta
       61 ttatttttaa acacgaatat tacagcattt tattgttttt tcgttcatct aaaagatact
      121 tacatttaat taacggatgt tattctattt aattgttcgc tagttttttt ataatgacat
      181 ccctgaattt ctcacttgct tgtattttgt accttattct ttgttggata tataaaaaaa
      241 caagtaaagc acatgcttta cttgtcttct gcctttgcga taggaataaa gattctaaaa
      301 attgtccctt gccctactac actttctgct aagatacgtc ctttatagtt ttcaaccagt
      361 tgtttagcga tagacaaccc cagaccattt ccacccttcg ttctagctct tgctttatcc
      421 actcgataaa aacgattgaa gatcttatta aggtcttctt tgggtattcc ttcgccaaag
      481 tcctgaatcg cgatctcaaa ttcattcaga gtggaagaaa tagagatatg gacttctttt
      541 cgtgtagttg aatactttac tgcgttatcc aatatgataa tgattaattg ttcaaagtga
      601 ttacgataaa tttgcagggt cacttctttt gtcaaatcat catctaaagt gatcacatag
      661 tctggatata atatcttgaa attattataa acttgatagg tgacttcttt tcctttagtt
      721 gtttcattcg cataatgaac atctacttgt tctgctcttg ataagtctag catctcttga
      781 actaagcttt tcatacggct gatttcttgc atgctggcgc ttaatgattc ttctaatatc
      841 tcaggatcat ctttccccca acgatttagc agactaagat gcccttcaat aattgcaaca
      901 ggtgtcctta actcatgaga tacgtcttcc acgaattgct cttgttgttc aatatacaaa
      961 cgcatacggt caagcatctc attgaatatt tcagctaaat ctgccaattc atcatttgtg
     1021 tcgatttcag gcatgtggat atctgattgc ggatctttac gtatagtatc cattgtatct
     1081 ctgagtacct tgagtggttt taagaaataa gaagataaaa agaaacctaa aatactactt
     1141 aagatcaaag aaacaacttc taaaacaata agagtcaata atagcttatt tcgaatatca
     1201 tagaaagaag ataattcata gaagctttgc gcatagccga tcttttctct tgtaccttta
     1261 gaatatatag gctggataga taaaaagcca gtttttcctt ctagtgtaac gatcgttgga
     1321 actttacgtg tagtctgaat caggtttcga ctgttttcat gggttttaaa aatcaagttc
     1381 tcgtccaaat cataaacata aagatccatt gatggctgcc ctagctcagc tataaaggaa
     1441 tcgatcttca ttaagtttcc ttcgaccagt gaagtatgat ctacgacctc atctccgtca
     1501 tttgtcgctt tcgtcagatt acgatacgta tttactaatg tcagttcttc atccgagtta
     1561 gccaaacgag aagctacttc tgaaatcgta cgctctacat tgtttctttc ttttgccaca
     1621 atcagattga tagatgattt ataggtaatg acagcgaaaa ttgtaaacac aacgaatatg
     1681 aagaaagaac tcgcaaaggc ccacttgatt gtcaaggagg gccctttcag ttctcttttt
     1741 tccgattttt tcggctttat cacgagcgca tcacataacc tgttccgcgt acagtttgga
     1801 tatagctttc ctccccggga acgtcaattt tgttgcgaag ataacgaata tatacgtcca
     1861 ctacgtttgt ttcaacttct gtttcgtatc cccacacttt atttagtaaa acgtcacgtg
     1921 ctaataccac gttcacgttt tccattaaag taagcagcaa ctcgtattct ctttttgtta
     1981 gttcaattac ttcatttccg cgacgtacga cacggttttc tttttcgata gtcaaatcgc
     2041 gataagtaat agtagtttgt ttagccacat ttttatcgcc ttcaatatcg attcgacgca
     2101 acaatgcacg aagacgtgct aataattctt cgatagcaaa tggtttgacg atgtagtcat
     2161 ctgctccgtg gtcaagtcca gatacacgat cgatcacaga atctcttgca gtcatcataa
     2221 tgattggtgt atttttgact tggcgtacac gtctgcagac ttctaaaccg ttcaattctg
     2281 ggagcatcag atccaacaat atggcatccc actcattatt taatgccgca tctaaaccag
     2341 ttcggccgtt gtagtggact tctgcgttat acccttcatg cttcaactct agctcgacaa
     2401 atcgtgccaa gttcttttca tcttcaatga ttagaatatt gctcatttat tattttatcc
     2461 tttctattct actggctttt taaaaactct atcattatac cgataatatg cttaaaaatc
     2521 tatagtcatt ttattatgga tagcaatttt aaaaaagagc tgaagtctac tcataacaat
     2581 cgacttcagc tctttcgtcc tctttttatt ttctcatttc ctaacagccg aaagactatt
     2641 attcttcatg gtaccatgag taatggaaga ttccttcttt gtcgacacgc tcataggtat
     2701 gtgcgccaaa gtaatcgcgt tgggcttgga ttatatttgc aggcagacgt tctgctctgt
     2761 atgaatcgaa gtaagcgatg gctgatgaga aagtcggtac aggtacgcca gcttggacag
     2821 ccaaggcaac gacgtctctg actgattgct gatatttttt cgtgatttca acgaagtaat
     2881 catctagcaa taaattttcg atctcaggat ttttgtcata ggcatccgta attttttgca
     2941 agaatcgagc tcggatgata catccagcgc gccagatttt tgcgatttca ccaaatggca
     3001 agtcccaatc aaattctttt gaagcgacac gtaattgagc aaatccttgg gcataactca
     3061 tgattttact gaaatacaac gcttctcgga ttttttcgac caattctttt ttgtctcccg
     3121 tgaactcaaa atcgttcgta cgagacaaaa tcttgcttgc ttgtacgcgt tcttctttat
     3181 aagcagaaat atagcgggca aatacagatt cagtgatcaa tggaagtggc acacctaagt
     3241 caagcgcgct ttggcttgtc catttacctg ttcctttatt cccagctgca tcaaggatca
     3301 catctactac tggtttacct gttccttcat cgtctttacg tgtcagaatg tcagcagtga
     3361 tttctatcaa atagctgtct aattcgcctt gattccattc tttaaagata tcagccattt
     3421 cttctactga aaggtttaaa atattcttca ttaagtcata agattcagca atcagttgca
     3481 tatctccata ctcaataccg ttgtgtacca ttttcacata atgtccggct ccatttgggc
     3541 caatatatgt gacacatggt gctccgtctt ctgcttttgc agaaatttgc tctaagattg
     3601 gtgcaactag cgcataggct tctttttgtc caccaggcat gattgaaggt ccttttaaag
     3661 ctccttcttc accaccggaa acgcctgtac cgataaagtt gatgccagag ttggctaact
     3721 cttcattacg acgcatcgta tctttaaaga atgtatttcc tccgtcaatc aaaatatcgc
     3781 ctttatcaag gtgaggaagt aactcttgga ttgttgcatc tgttgccggt cctgctttga
     3841 ccattagcaa gatccgacgt ggtttctcga tagattctac aaattcttcg attgtatatg
     3901 ttgctttgaa atttttatct gggtgttctt ctactacagc ggttgtttta gcccctgtac
     3961 gattgaataa agccactgaa tagccgcggc tttctatgtt caaggctaga tttttaccca
     4021 taacggccat accgacaacg ccgatttgtt gttttgacat atgaactcct cctacatacg
     4081 ggatttctcc ctaatctctt acattatagc ttaacacggc tacattgcaa actaaagaac
     4141 aacatatttt ttatttaccg actacaaaaa aataaacctc aaggctccat ggttagcctt
     4201 gaggttttac attttctaat taaaatgtat taagcttctt ttgacattac gtccttacca
     4261 tcatagtaac cacaatttgc acatacgtga tggctttttt tcatttcacc acagtttgga
     4321 cattcgttta accctttgat tgtcaatttg tagtgtgtac gacgttttgc ttttttagct
     4381 tttgatgttc ttctagctgg tactgccatt ttgctacacc tccttgtaaa gtcttgtatc
     4441 taaattagac acaatatatt ccaatcttac ttgttatcgt cgtcttttga tttagaatca
     4501 aaaagttcag atagttttgc aagacgagga tcaattttat tctcggcttc ttccattttt
     4561 ctgcgctggt attcttcttc ggaaacaact tcccaatcat tgccttttgg aagttctgtt
     4621 gctgcttcct cttcttttgt caatacccgc attggaatcg ccaataagat gttgtcttca
     4681 atcgactctg ctaaattcaa taatggacct tcaattagca aaatctcatc tgcagacatt
     4741 tgttcatctc tactttggaa ttgttcttct gtcatgaata cttcgtctac agaaaaatcc
     4801 atgggcagtt caacaggttc tagtgaacgt gttgaaggaa ctgtcaaagt cgtctgcaca
     4861 gtgtaatgaa cgatatagcc tttcttatca actgagacca aaccttcgac ttccactggc
     4921 gcaacatcaa gtattaaatt gtctcgcttc atgagagcgg ctttcaagtc gagcgtctca
     4981 tgaaaagtta acggtgtctc ctggtatttt ctcaattcca ataaagacca tttcattttt
     5041 catcactcct aagcaacaaa agcaattata cagggcaaaa agcatgttgt caatgaaatt
     5101 ttcttgacac cttgcagttc ataaaaaaac agaaaaatct ttattagaaa gcctctgttt
     5161 gctatcatcc tcagaatcat ttacaataat cattattcca ttaaaggagc ggatgatctt
     5221 catgaacacg aaagatatcg aatactatgt ccaaatcgtc aaacaaaaaa attttacgaa
     5281 agtggctaat tatttccgtg tgagccaacc tactattaca tatgcattac aacgtcttga
     5341 aaaagagttt gacaccgtac ttattacaag agatcgatcg catcacgaat tgatcgtcac
     5401 gccttctgga aagcagctgt ttctccatgc acaaaccatt ctccaagaga tttctactgc
     5461 aagagctgaa atcactcagt tgcaaaagaa aaagcttcgt tttggcatgc ctcctattat
     5521 cggcaatgaa tactttccta aactgtcaag ttactttatc aagcatgaat tgatgaatca
     5581 aattgagatt accgatggag gctctcggga cttatacggg atgatccgac aagggaggat
     5641 cgatttagct gtattaggct caacacagcc aatcgtggat caatatttag aaacagagtt
     5701 acttttggac aaacgtttca tgatcgtcgt gccacctaca catcctcttt ccaagcagga
     5761 tactgtctct ttcaaagata tagcagatga acagtttgta ctattgaacg aacattatgt
     5821 ccaccccgca gcattcacta agctttctaa acaaacacat actcatccaa aagttgttta
     5881 tcaaagcaat gacttgacga ttttaaagag tatggtccga gaaaatgtgg gtatcggttt
     5941 tttggcagag attgctgtcc atcctgaaga tcatttagtt tgcctccctc tttcagatga
     6001 agttcagcct cgcttcttga tttcattggc aaaacgaaca cagcagatcg tcacgcctct
     6061 tcaagaacaa gtagtccaag ttatccatga attcgttaca gcacaaaaaa acagctcttc
     6121 gtaaaagaag agctgttttt attttttatt aagctaaatt agatagctgt tgtttcgcca
     6181 cggtaaacga tgccgcgacg tgaatcaacg gtaatcaatt caccttctgt aattgttgtt
     6241 gttgcgcctt tagcaccaac gattacagga atatcttgtg caattcctac aactgcagcg
     6301 tgagaagtca atccgccttc ttcaacgata acagcagctg ctttttcgat tgcaggcata
     6361 tattctttgt cagttgatgg tacaactaga accattccgt cttttgcttt ttttacagct
     6421 tcttcagcag atgaagcaat aactgcattt gcaacgacag atttttgtcc aacgccttga
     6481 gcttctaata atttagaacc aatcatttga attttcatca cgttagttgt tccgcgttca
     6541 ccaactggta caccagcagt gatcaagatt aaatcgcctt ctgatgcgaa acctaattca
     6601 acagcttttt tagctgctag ttcaaacatt tcatcagttg ttgatggttt ttcagcaact
     6661 gttgggtaaa cgccccagtt taacatcaaa ccacgttttg tgcgttcgtc aaaagtaaca
     6721 gccaagatat ctgcatctgg acgatatttt gaaatcattt ttgcagtgta tcctgattca
     6781 gttgcagcaa cgattgtttt cacgcctaga ttttttgcag cacgagctac agataaaccg
     6841 attgtttcag ttacatctgt tttatcgaat tcgttcaatt ggaatgtacc taattctgat
     6901 aatgcatttt cagcttcttg gtcgatacgt gccattgttg aaacagcttc aactgggtag
     6961 tccccgtttg cagattcacc agatagcatt gttgcatctg tgccatcaaa tacagcgtta
     7021 gcaacgtcag aagcttccgc acgtgttgga cgtgggtttt cttgcattga ttctaacatt
     7081 tgtgtagcag tgataactgg gataccagca gcattacatt ttttgataat gcgtttttga
     7141 accattggta ctagttcagc tgggatttca acacccatat ctccgcgggc aatcataaca
     7201 ccgtcagaaa ctttgatgat ttcgtcaatg ttgtcgatac cttcttgaga ttcgatttta
     7261 gggaagattt gaacatgagt catgtctttt tcttctaaga tttcgcggat atctagaacg
     7321 tcttgtgctt tacgtacaaa acttgcagcg ataaagtcga tatcgttgtc taaaccaaaa
     7381 cgaatatcgt cagcatcttt tggagtaata cctggcaaac taatagaaac gcctggtgca
     7441 tttacccctt tacgtgatcc tagcatacct gcatttttaa cttctacgac taattcacgg
     7501 tttgcttcgt ctttttcaat gatttgcata tcgatcaaac catcatcaaa taaaatgtgt
     7561 ccgccaacgt gaacatcgtc aaataatcct gggtaagtaa ccgcgatttt ttcttttgaa
     7621 cctacatgtt caggatccat agagatgcgt gtttgatctc ctacttcaaa tttgatgtat
     7681 cctgcacgac caaaatcagc ttctgttgtg ccttgaacag ttgtacggat ttcagctcct
     7741 tttgtatcta aaagaatacc gacatctttt cctgtctttt taactgcttc acggaccata
     7801 gtcatacgtg ataattgttc ttcatggtca ccatgagaaa aattaaagcg gaagacattt
     7861 gccccagatt caatcaattg agaaataatt tctactgagt tacttgctgg tcctaatgta
     7921 ctaacgattt tggttttttt catttaaaaa actctcccat tcaattttgt ttatttaaag
     7981 ctgtacacag cttaaatagc ttggtttctt tcactcttaa aatgaaagtg aattatttag
     8041 atcatatagt gataagtctg gtttatgttt gttgttttca agtgtatcaa tgatgtcaga
     8101 cgcaacgatt tcgttgtcat ggataccgac acataatcca ccttttcctt cttgaagcaa
     8161 ttcgacagcg taagcaccga atttacttgc caacacgcgg tcgcgtgcgc ttggtgctcc
     8221 accacggaca acgtgtccca agatagatac acgtgtatga tagtcaccaa attctgaaag
     8281 tttctcagcg aattcatttc cgcccattac accttcagcc aagatgatca agcaatgttt
     8341 cttcccgcga tcgcggcctt cttggatttt tttagcaact gaagccatat caaaatcatg
     8401 ttctgggatg atgatttcat ccgctccgcc agccacacct gaccataaag cgatgtctcc
     8461 tgcattgcgt cccattactt cgataacgaa tgtacgaaca tgagaagtcg ctgtgtcacg
     8521 aatacggtca attgattcta gtactgtatt gattgctgta tcaaaaccga ttgtgaaatc
     8581 agtcccagga atatcattat cgattgttcc aggaatacct actgctggga aaccgcgttt
     8641 tgtcaaagcc attgcgccat gataagagcc gtctcctccg ataaccacta gaccttcgat
     8701 tccgaatttt ttcaattgtt cgattccttt taattgacct tcttcagttg caaattctgg
     8761 ataacgtgca gaatacaaga atgtaccacc acgttggatc ttgtcaccta catctgccac
     8821 atcaagacga cgaatatctc cagcaactaa accggcaaaa ccataattga tcccgtatac
     8881 ttccagtcct tcgtaaatac ctttacgaac aacggcacga acagctgcat tcattccagg
     8941 tgcgtctccg ccactggtca aaattccgat gcgtttcata ataaacattc acctcattaa
     9001 aatactttat cctaagtatg acttaggttt acaaccattt ttgcgttaac cacgactaac
     9061 attctaacat tatttttctc acttgtcttg atttactgat aaaaaaatga aaaaaaatga
     9121 aagcaagtag tattttttac cgtaagttat ttgaaaacca cattatcttc gccaagcaga
     9181 taaataagtt gccgctttat actcttgctg tcatccaccc aataagcatc tgacagaact
     9241 acttttcgtt gcgttttttc gtgatacata actactggta tatatcctgg gtgtttctga
     9301 aaaatcactt gtaattgttt cattatctcg ggatcttccc gttcttctgt aatacgcaaa
     9361 tagcaagttt gtgaaggata ctgggcttct aactggttag gatcagcaaa gctttctcca
     9421 attagttgca gttcctgatt atatttgctg atttcgctcc gcccttgaac aaagatcact
     9481 cgatcaacgg caaacaaatt acgatattta cgataaagag ttggaaaaac tgtgacagaa
     9541 atttctccac tactgtcggt tccttcaaca aaggccatca gttctccttt ttttgtccga
     9601 atttctctaa cttccttgat catcactaat aaattgactg gttgattagg gacgatatct
     9661 gtaatcagct gaacttgttt agctaaacga agacgatcaa acccttctgc aggatgacct
     9721 gacaaataaa tacctaagta ctcctcttcc agcttcaagc gttcttctag tgtatagtca
     9781 gcgacttctt cttcttttaa tgccatgatt cccagcaagt caagacttcc accactgtaa
     9841 acgatatttt ggatttttcc ttcgagatca agcatcaatt gtttcctgtt aggagataat
     9901 tcatcaaaaa ctcctactgc tgtcagtgat tgcagtaact ctaatttcag ccaacgctta
     9961 tcgatccgta tgaggaattg atccactgac tggaacgggc cattttgttt tctttcgttt
    10021 aatatatctt ctacaaaatc acgccgaata ccttttatcg ctgtcagtcc gaatctgatt
    10081 tcttccttat tgaccaactc aaaactggaa ttactttgat taatggacgg cgaggaaagt
    10141 ttgagtttat ttttacgtgc ttctgcaata tattctttca attttgatgt gttatgccga
    10201 acagaattca tcaggctggt aaagaaagca cctggatgat gggcttttag atacgccatt
    10261 tggaatccca cgaatgaata agcaaatgca tgtgaccgat tgaatccata gtttgcaaat
    10321 ttttcgatat attcatatac ggtcgctgct gttttttccg aatatccctg ttgtaatgct
    10381 cctgatacaa aatgcgactt ttcttcatct aatacgtctt ttttcttttt actcactgcc
    10441 cgtcgcagaa tatctgactg ccctaatgta aatccagcca tagtcgaggc gatctgcatg
    10501 atttgttcct gatagacgat cactccatat gtgtttttca aaatcgggat cagtgaatca
    10561 tctgggtagc gaatggcttc ttttcctttc ttcctggcaa tgaaggtatc tatattttgc
    10621 atagggcctg gtcgatacaa tgcattgact gcggcaatat cttcgatgtt ttctggatct
    10681 aatcttcgta aaacgttccg gataccagca gattcaaatt gaaatactcc tgaggtttcg
    10741 cctcgttgaa acaagagcag cgtttttgca tcatttagcg ggatctcttt taatcggatc
    10801 tcataccctt ctactcgctt aacagctttc aaagtaaaat caataatcga taagttgcgt
    10861 agtcctaaaa agtccatttt caaaagaccg attgcttcta cctcattcat cgtatactgg
    10921 gtcagaaaag cttcatcaga accgcgttgg agcggaacta gttcaagtag attcttatcg
    10981 ctgataacta cacctgctgc gtgagtcgaa acatgtcttg gcaatccttc taaaatcact
    11041 gcagttttga ataaaagttg gtttttttcg cttgcctgaa ctaattctac taattgatgc
    11101 gaagttttat aagcttgggt caatgtgatt ttcaattgat tgggtattgc ttttgaccag
    11161 cggtttgctt cactttgcga taaaccaaac actctagctg catctctaag aaccattttt
    11221 gctgccattg tgccaaatgt tgcgatttgt gccatatgat attgtccata cttttctcga
    11281 acataattca atacttcttc acgtcgattg tcaggaatat ccaaatcgat atctggcatc
    11341 gtaaagcgtt cggggtttaa aaagcgttcg aacagcaaat catattctaa tggatccaca
    11401 tctgtgattt ctaacacata ggctactaat gaacccgcag cagaaccacg acctgcaccg
    11461 gtaacgattt tgtttctatg agcaaaagcc attacatccc atacgatcaa gaaataatca
    11521 tcgaatccca tttgatggat gacagataac tcgtagtcca aacgttcttg gtattccttt
    11581 gtatagtcag tgattcggcg ttccacttgc gaatagcata actctcttaa atattctcca
    11641 gcttgttttc cattaggaac tggataatgc ggaagtaatt tctgatggaa ctggaattca
    11701 aatgaaatcg attcagctaa acgctgggcg cctattacag cttgggaaag acccgctttt
    11761 tcgaatcgtt tgatcatttc ttgttctgaa agaagataga catttgctgt tagtggtaaa
    11821 gatgcagata aattttctaa aggtatttgg cttccctctt tgatatgttt catcacttca
    11881 agtgcaaaaa gttcttcttg ttgtaaacta gcgatgggat gtaatgcaca aagcgaataa
    11941 ttttctttta tcacatactg ataccattca ggcaattgat caggcgtgtt ttctgtcaag
    12001 ccgatataaa aatttctagt aaaaacattt tcaagtaaaa actgccaatg accgaaaaag
    12061 ttatcctctt tattgaaagc ctcagaaaca gaatgatttg ccggaacaac aaacgctaga
    12121 tggtcggttt ctgtcatttc tgcaagttcc aatttttctt ggatcatttt tcggctggaa
    12181 agtttcatca gctgctgata acctatttca tcttttgcgt acgcaagcaa gccataattt
    12241 ttttcttcat aagtataact aagatgtaat ccaatgattg gctgtactcc ttcttctaca
    12301 caaatacgat agaattcagg tgcaccgtat aagacatctt tatccgttat ggctaatgaa
    12361 gtgtagcctt gtttttttgc ttcttgtaca tattctcgaa tacgtatcgt actttgtaaa
    12421 agagaataag aagtaattgt ataaagttgt gggaaaaaca tcttgcattc cgcctttttt
    12481 ttcgttaaaa ttcactagcg ttaaaaggtt tgatcctttt actttcatta agatagcagg
    12541 cgctgaagtt gattattcca cttcatttgc ttgcttgtaa tctgtaggaa tgagttcttt
    12601 cgcaagaact caaattttat tgagatttgg tctcgtttct ttacattcaa agaaaatctg
    12661 gtaaaattaa gatagaaaag aggtgttctt tatgcgatat atcgttacat tattctgggc
    12721 tgtcgttcta ggtcaagtag tcggttatat tggtgctgca ttaacaagcg gaacatatga
    12781 ttttactttg acaacaatca tttcattcat tgcgggtgtc attatccttt tgattggtgc
    12841 agttgcgcca agaaaagaaa cctctgccca ttcgtaaaaa aacagccaag agcttgagat
    12901 ttctcaagct cttttttatt ttctactcct caccaccatt ataatctgct gcgaagaact
    12961 ttacgaaagt tgaataaaga aagaagaata tttgacagaa caaacaaact tgtcacaata
    13021 aaaacagcac tgtaattata agcatgcgcg actgtcgatc ctagcatggg acctaaaact
    13081 tgtccaaagt tgctaaacat ctgattgtag ctatagattc ggctgactcc ttcttgaggc
    13141 gtaatcttac tgatcagtgt attgacagaa ggcatcaaag cgccagttga aaagcctaaa
    13201 ataaagcgaa gtatacctaa ttggagcggt gtagtgacga atgccatagg taaataacag
    13261 caaaatgata aaatgagtcc tccaattaga actttttgat tcccaatctt atcccctagt
    13321 tttcctagtt tcggtgaaga aaagacagcg gaaacaccag ctatcgaaac aatcaagccg
    13381 ctgacaaaaa ggatattttc tgtacttccg ctcaattcac gaatatataa ggtcaaaata
    13441 gggctgatcg tagtgattcc tatctgtaaa atcaaggtcg taatgaaaag accgatcaaa
    13501 atagagagat gatccatttt tgaaaaaatt tctttggtgc ttatcagatc ttttttctcg
    13561 attggatgga aatcttcttt gactaagaaa atggtcaata ccgttgtgat catcaacaaa
    13621 gcccctgtga tcaagaatac attttccata ccaaaccact gagccagtgc accgcccatt
    13681 gaaggtccga tcagatttcc agcaatcgct ccggtagaca atgttcctaa cgcccatccg
    13741 ctcttttctc taggtgcctg tgaagcaatc atcgctgtgg catttggaat atatccagac
    13801 aaaatcccat tccaaaaccg catgatcaaa agccaatacg cgtttggtac aaaagccaaa
    13861 gatcccattg ttaatgtcat ccctgctgct gcacggatca tcatgagttt tcggcctttt
    13921 cgatcagcta gatttcccca gattggtgca accacggcag atgcaaaagc agtcacagag
    13981 attgctagtc ccgaaaacaa ttcgatttga tcttttggtg ttcctagttg ctcaacataa
    14041 actggtatga atggcataac taaactaata cttgcaccag tgaaaaaaca gccaatccac
    14101 gcaatcacta aattttttct ccaattaatc tccatctatc atccctcttt cgtctctttt
    14161 atcataccta ttttcgaata aacaagcaac gatctcgcca gtaaaaagag aaaaatcccg
    14221 caaaggtcat tttatatgta acgttctttt tatgtaaaac aaaaagagat cagaacaaat
    14281 actgttccaa tcccttctct ttagttaaat tgttgctaga atgatgaagt tgataatgaa
    14341 taaaatatca acgatccaca aagcaacaga aacttgattg tattttcctt tgattacttt
    14401 cacaattgta tagaaaataa atcctgctgc aatcccatag gaaatgctat agcacaatcc
    14461 cataaagatc gatgcaaaga aggccggtaa agcttcttcc atatctagcc atttgatgtc
    14521 tgcaaaagaa gccatcatca ttactccaac taaaatcaat gctggcgcag ttgcttgatt
    14581 tggtacaatg gcgatcagtg gagagaataa actacttaat gcgaatagca ctgccactac
    14641 tactgaagtc aaaccagtac gtccaccggc cccgatccca gctgcagatt cgacataagt
    14701 tgttgtattc gatgtaccaa agatagcccc cacagaagta gcgatcgcat cggcaaatag
    14761 tgctttatcc atttttgttt tgaacccacg accatcttcc aacgcgatct cgtcttcttt
    14821 tgagaaaata cctgtgcggc gtcctgtacc gataaatgtt ccgatcgtat cgaaagtatc
    14881 agataaactg aatgcgatga tcgtcatcaa tacttgagga atcttggaag aatcactgaa
    14941 taaagattgc atgccttcag aaccaaatgc tgcaccgaaa gttgttccta attctttaaa
    15001 tgaattacct aacgaattcg tttgccaatc aatggaactt aaatcaacaa cacccataaa
    15061 aataccaagg actgtggtcg ctacgatacc gataagaata gccccacgga cattttttac
    15121 aactaaaatg gctgtcagta ccaaaccaat cacagccaat aagataggag cgttgtcaaa
    15181 gttggctaac gcagggacga ttccaccatt tatcgtaaca tttgtcgctt ttccgccttc
    15241 aacgacagag ctcgaaatag ctgactggtc tgctgaaaaa gataagaatc ctgcattttt
    15301 gattccgaca tacgcaacga aaataccgat cccgccacca atcgcatgtt gaagactttc
    15361 gggaatcgcc cgaataatca tttttcgaat atttgtgaca gtaataaaaa tattgattaa
    15421 tccgcaaata aacaccattg ccaaggcttg ttgccaagaa taaccaagcc caaaaacgac
    15481 cgtaaaagtg aaaaatgcgt tcaatcccat accaggtgcc tgagcatatg gtacatttgc
    15541 gaacaatccc attaccagcg taccaataat cgatgcaatg attgtcgcta gaaatactgc
    15601 ttggaagggc atacctgatg ctgacaaaat cgtcggattt acgaataaga tataactcat
    15661 ggcaaagaat gtcgttactc ccgccattat ttcagttgat acatttgtat tgtttttctt
    15721 taaaccgaaa aacttttcca taaaaagttc cactccctga atttttttct gatggaaaac
    15781 tataataata aaaaataagt aaaatagggc aaatccatcg aacaatttca aattatatag
    15841 acgtttcatt cgcttttcaa cgttttttta acaaaaaaag cgaaaataat acttaacgtt
    15901 cgtgtttagc ttatgtttag ctatttatat agccataact gtagtttttg ttaggaatag
    15961 ctgattgctc ttgttaatta cctaaaatat gctagactaa aacaaatgct agttgaggaa
    16021 ggaaggaccc ttattgaata aaaaattaat tgccatcgat ctggacggaa ctaccctcaa
    16081 tcaagattcg atgattacat ctaaaacaaa agagactcta aaaaaagcaa tcaatgccgg
    16141 tcatcatgtc agtattgcta caggacgccc attccgaatg agccatcagt tttaccaaca
    16201 attagaatta acaacaccga tggttaattt taacggcgca ttagtacaca tccctaatca
    16261 gcactgggat ggtgaaagag aaacgttgat caatcgtgaa atcgcttttg aaatcttatc
    16321 gcaaaaaaag cagctaaatt tagattttat cgctgctgaa aatcgtgata ctttttttat
    16381 tgacagtttt gatttctttg atgaaaaaat ttttgcttct tctcgtccag gagagaagaa
    16441 tttgctttct cctaaaaatt tgacgacaaa tcctacatct ttgcttgtcc gaacagacaa
    16501 acgttttgca ggagctgtat ctgctgaatt aacacgtcaa tttggcagtt atgtcgatgt
    16561 tcggacatgg ggtggaccta ctgccatctt agagattgtt tcaaaaggaa tccaaaaagc
    16621 aaaaggcgtg caagagattg ctaactacct gtctatcgat caaaaagacg tcattgcctt
    16681 tggtgacgag cataatgatt tggaattgtt ggattatgca ggttggggag tagctatggc
    16741 taacggtact gaccaactca aaggcattgc aaatgatgtc actcctttga gcaatcagga
    16801 agacggttta gctgtttatc tggaaaaact acttaaacta taatagagaa ttagattcca
    16861 caaaaaagag gttgtgacaa tttt
//
LOCUS       DACGMI010000062        16550 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.064, whole genome shotgun sequence.
ACCESSION   DACGMI010000062 DACGMI010000000
VERSION     DACGMI010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.064"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..1259
                     /locus_tag="IXT46_002320"
     CDS             <1..1259
                     /locus_tag="IXT46_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4948219.1"
                     /translation="VIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGT
                     VDLTDNVTNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEV
                     TDNRSNADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKK
                     GTIVVTYPDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDL
                     PKGTTYTWKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITE
                     GDQIVTGKTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESGN
                     TSEPTNVVVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSNI
                     FTISGGLILLGTLGLLGYKNRKKENE"
     gene            1393..2736
                     /locus_tag="IXT46_002321"
     CDS             1393..2736
                     /locus_tag="IXT46_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4948220.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2848..4251
                     /locus_tag="IXT46_002322"
     CDS             2848..4251
                     /locus_tag="IXT46_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAQ4948221.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTISS
                     TESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPI
                     LSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQA
                     PNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGI
                     SGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGP
                     QMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSW
                     GNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDS
                     SLSQSMLVDPKTLLFGD"
     gene            4600..5232
                     /locus_tag="IXT46_002323"
     CDS             4600..5232
                     /locus_tag="IXT46_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HAQ4948222.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            5820..7259
                     /locus_tag="IXT46_002324"
     CDS             5820..7259
                     /locus_tag="IXT46_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4948223.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7554..7772
                     /locus_tag="IXT46_002325"
                     /pseudo
     CDS             7554..7772
                     /locus_tag="IXT46_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8021..8236
                     /locus_tag="IXT46_002326"
     CDS             8021..8236
                     /locus_tag="IXT46_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948224.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8453..8709)
                     /locus_tag="IXT46_002327"
                     /pseudo
     CDS             complement(8453..8709)
                     /locus_tag="IXT46_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(8896..9807)
                     /locus_tag="IXT46_002328"
     CDS             complement(8896..9807)
                     /locus_tag="IXT46_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4948225.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(9826..10830)
                     /locus_tag="IXT46_002329"
     CDS             complement(9826..10830)
                     /locus_tag="IXT46_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAQ4948226.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(10827..12950)
                     /locus_tag="IXT46_002330"
     CDS             complement(10827..12950)
                     /locus_tag="IXT46_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4948227.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(12955..15402)
                     /locus_tag="IXT46_002331"
     CDS             complement(12955..15402)
                     /locus_tag="IXT46_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4948228.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(15389..15778)
                     /locus_tag="IXT46_002332"
     CDS             complement(15389..15778)
                     /locus_tag="IXT46_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4948229.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(15838..16341)
                     /locus_tag="IXT46_002333"
     CDS             complement(15838..16341)
                     /locus_tag="IXT46_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAQ4948230.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(16354..16515)
                     /locus_tag="IXT46_002334"
     CDS             complement(16354..16515)
                     /locus_tag="IXT46_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002392227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948231.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         5342 a         3078 c         3047 g         5083 t
ORIGIN      
        1 gtgtcattga agtaacgtat ccagacggta cgaaagatac ggtgaaagtt ccagtagaag
       61 tgacagacaa tcgttctgac gccgataaat atgaaccaac agtagaaggc gaaaaagtag
      121 aaattggagg cacagtagat ttaacagata atgttactaa cttgccagcg ttaccagaag
      181 gaacaacagt aacagatgtt actcccggcg gtacaattga taccaacaca ccaggcaatt
      241 atgaaggtgt cattgaagta acgtatccag acggtacgaa agatacggtg aaagttccag
      301 tagaagtgac agacaatcgt tctaatgcag ataaatacaa tcctgaagga caaaaagtga
      361 ctacagactt aaataaagag ccagatgcat ctgagggaat taagaacaaa gaagatttac
      421 caaaaggaac tacttatgct tggaaagaga aagtagatgt tagcacagct ggaaataaaa
      481 aaggtactat tgtagtgaca tatccagatg gatcatctga tgaagttgaa gtagacgtta
      541 cagtgacaga tactcgttcc gatgcagata aatataatcc tgaaggacaa aaagtgacta
      601 cagacttaaa taaagagcca gatgcatctg agggaattaa gaacaaagaa gatctaccaa
      661 aaggaactac ttatacttgg aaagaaaaag tagatgttag tacagctgga aacaaaaaag
      721 gtactgtagt agtaacatat ccagatggat ctaaagaaga agtagaagtt actatttctg
      781 tagtagataa aaaagcaccg aataaacctc aagttgatcc tattacagag ggtgaccaaa
      841 ttgttactgg taaaactgaa ccaaatgcag aggtgacagt tacattacca gacggaagtc
      901 aacaccatgg gacagctgat aaaaatggta attttacagt taaagttcct aaattagagg
      961 cagggacaaa agtgatagta actgcaactg atgaatctgg taatactagt gaacctacta
     1021 atgtagttgt ttcttccaac aaaaaagaca gtggaaaaaa cggtagtaaa ggtagtaaga
     1081 ctgacaatca aggtagcaac agcaatcaag acaaaaatag aggcaaaagc cagtcctcaa
     1141 aagtttttcc taagacggga gagagtgaca gtaatatctt tactattagc ggtggtttaa
     1201 tactgttagg aacgttagga ttattagggt ataaaaatcg aaaaaaagag aatgaataga
     1261 aaatcaattt cttaagtctt ctctgagaag aggaagaatc tttttcttcc tctttttgct
     1321 tttttatgat gggaaataag tgttagttaa agatgaatat actttttata gaaaggaaaa
     1381 gaatgtaatt aagtggaaaa aatagtaatt attggttcaa accattcagg gctagccgca
     1441 gctcgatttc taaacttaag cgattcaaat tatgaagtta ttctaatcga taaaaaatca
     1501 gaaattagtt acttggaatg tgggacatcg ttatttataa aaggagaagt aagtaattta
     1561 gaagatcttt tttatcaaaa tagaatgaca ctaaattctg agataaaaaa gttatttcta
     1621 gagacagaag ttgacaaaat tgatattcaa aataaaaaga ttagttgtgt aaaaaaagat
     1681 ggtacaagat tctctcaaga atatgacaaa gttatattag ctacaggttc aaagcaaatt
     1741 atgctagata taccggggaa taatttagct aatatttttt cgataaagaa ttttccaaat
     1801 gcaaaagaga tttttaaagc tttggatgat agtactatta aaaaagtagg aattattgga
     1861 gcaggatata ttggagttga aattgctgaa gccataagaa aaagagggaa agaagtatat
     1921 cttttcgatg ttgcagatag agtgttgtcg acttattacg accgtagttt ttcagataaa
     1981 gttgaagaaa tactatcaaa aaatggaata catctttgtc tatcagaaag tcctaaaaaa
     2041 tatttaggaa gaaaaaagat tgaaaaaata gtcactacaa gtggtaccca atactctatg
     2101 gatatggtcg tacaagctat aggatttcta tctaatagtc caattgggga aaaggaactc
     2161 ttgagagatg ttagtggagc atatctaact aatgaatacc agcaaacaaa tataaaagat
     2221 atatatgcta ttggggattg tgctacaact ttttttacgt ccattaatag aagtagtgtt
     2281 gatttttcta tttctaatgc tctaagaaca gcttatattg caactcaaca tattaacaat
     2341 caagatttta caccttctgg ttcccaattt acaaatggct tttctatatt taattacaat
     2401 ttttacgcag caggtttgaa tttaaaaaca gcacgattat taagtgagtc tatagattat
     2461 atagaaatag aagatttcat tagacctgct tttttgagaa aaaatagtcg tgtaaaatta
     2521 agaattagct ttgaaaaaaa tacaaagaga atagtaggtg tacaactttg tagtcaagaa
     2581 gatttatctg gactattatc aatgttttct cttgctatag aagaacaaat tacattagac
     2641 aaattgaaaa tgttagatta tttatttcat cctagtttta gccaacccta taattttatt
     2701 ttaaaggcag taacaggatt aaacattgaa acataatcgt tactaaatga aatcaagaaa
     2761 tatactgtat tactcaattc attgaaaata tttatcataa tttttaatag aaaacactat
     2821 taaagagaaa aaagagaggt aaatcaaatg aaaaaatctt taaaacttgc atcagcagtt
     2881 atattaatgt cccaactcct tatagcaaca cctttccatg tgttggcaag cgaaaattca
     2941 acatacaaaa ttgcaaaaga aagaaccgag acgactgaaa tgagtaattc cgatgtaaca
     3001 gcagagagta gtgaactttt gacaacttca tcaagtgaaa gtagtacgac ttcaaatgcc
     3061 gagtcttcaa caacttcatc aagtgaaagt agtacgactt caaatgccga gtcttcaaca
     3121 acttcgtcaa gtgaaagtag tacgatttca agtaccgaat cttcaacaac ttcaagtagt
     3181 acaagtgaaa taacttcttc gaaagtgaca aaaccaaacc atatagaatc ttcaaaaaag
     3241 gaagcgccaa aaacggaagg acaaacaaaa actttttcga caccacagca aatagaatca
     3301 acagaatctt tccaatcaca accaatacta tctggtaatg aagaaattca ttttgacaaa
     3361 aatgaatctg tagaaaattt tattatgaaa attggtgagt ctgcgagaaa aattggtcag
     3421 aaatatgatt tatatgcttc tgttatgatt gcacaagcga tcttagaatc tgccagtggt
     3481 caaagccagt tagctcaggc accgaattac aatttatttg ggataaaagg aacttataat
     3541 ggaaactttg tcattatggt aacaaacgaa gatttgggta atggaacgct ttatacgacc
     3601 caatcaaaat ttagagtgta tgaaaactat gaggaaagct ttgaagatta tgccaaatta
     3661 ttaactaagg gaattagtgg aaataaagat ttttatgcag gagcattaaa agctaatagt
     3721 aaaacatatc gagaagcaac taaattcctt acaggacggt atgcaacaga tacacaatac
     3781 tatttgaagc taaatgaatt aattaaaacc tacgatttaa ccaactatga taaagaagtt
     3841 aaaggtccac aaatgagtaa gactggatac caagtgccta ttcataatta ttcaataacc
     3901 agtttgtttg gaaatcgtgg aaatgaattt caccgaggac ttgatatggc agctacacag
     3961 ggtgagccga ttcatgcagt taaagctggt aaggttgtta aagcagagtt tcactactct
     4021 tggggaaatt acgtggtgat acaacacgaa gatggatcaa ccgcgttata tgctcaccag
     4081 caacaatacc tagtaaaaac tggagataat gttttgcaag gacaaataat tggctatgta
     4141 ggaagtactg ggaatagtac tggcccacac cttcatttgg aaatttgcaa agatagtagt
     4201 ctttctcaga gcatgttagt tgatccgaaa accttattat tcggagacta aaaaaggtaa
     4261 tcaatctgac aaagtaacaa gaaaatggtt ggattcttag acctttgatc aggatattga
     4321 gactggaatt gatatctcga ttacgatggg tttgacaaat aaaacaagtc cattatcgaa
     4381 tatcgagtgt attattgccg tctttatgct catattttga gcaggtttca ctagatgaaa
     4441 acaatttatc tatcttgagg atttcgtgta cgtatcgttc agtcttgtat tgtaaattag
     4501 tcataaaatc agactaagaa aaattggaaa tatttttttc tgatttatta aaagttaatt
     4561 gaaattatat ggtacttctt tcttgggagg gtaggtgcag tgaaggaaag atatggtcac
     4621 cttactgttg ttgaggagat tactcataat ggatataaaa aatatcgttg cctatgtgac
     4681 tgtgggaatg aaacgattgt atatcgatca aacttactat caggtagaac caaaagttgt
     4741 ggatgtggaa attataaaaa taggcataaa tataaaaatt tgacaaataa aacttttggt
     4801 aagttagttg caatcaagcc aactaaactg cgaagtgaag gaactgttgt ttgggaatgt
     4861 caatgtctgt gtgggagaaa aaagttagta tcggcaaagc gacttctaaa aggtgatgta
     4921 aaaagctgtg gatgtttgaa atcaaaaaag catcacattg aaaataaaaa attcggatta
     4981 cttactgcaa agtatccttt ggacaataac tgttcatgga aaacaaaatg ggtttgtcat
     5041 tgtgagtgtg gcagtatgtg tgagataagt tatagtaact tattttttgg acatactcaa
     5101 agttgtggat gtttaaaaag gcaagaaaca aggacatgtg ttgaagggac agtaatagag
     5161 tgtctaacgt caaaattacc gaaaaataat acaagtggtg ttaagggagt ttatcgttct
     5221 aaagagaaat agattgcgta tataacttta aaaaaaaaga ggtactattt aggatcgtat
     5281 gattctatta agagtgcagc tcaagctaga aaagatgctg aaaataaatt gtttcaacct
     5341 ttgattgaca aatatcgagg taatcattaa ttattgtgga taataattaa cagtgatata
     5401 taaacatcta taatatatta ttcatactat tgatatttag tataatccta tggaattgaa
     5461 tatcatagca atgtatttga aaagcaaatt ggaaaacaaa taggtgcaac accataaata
     5521 tgaaaaaatt gggaaaaagt agaatggaaa tttgcttacg tctcacgaga tagctcacac
     5581 tattaatctg aagaacaatg aagtcgactt ttagaaattg ctagaagaaa gtaaagcgaa
     5641 ttatcactag ttactataga gtaagttcaa ataaagcatc tccaacttac atggttacat
     5701 gaggatatca aatcgaaatt actcaagctt cctatggcta gagtcgcgag aagttgttgg
     5761 gcagtagaca taggttatat tgttcttagc tacacgatca ttagaaagga aatcctatta
     5821 tgtatagtta tcaagaagat gcaaaagtcc aaaaaaatcg ctggtggatt ttgattgcta
     5881 tatctatgtt taccttcatg tccacattgg atggcagtat tgtcaatatt gcactaccta
     5941 ccatctcaga tgatatgggc ataccaatga atcaagcgga atgggtagtg tccgtttatc
     6001 tgatgattgt ctgttcttgt ttgttgctgt ttggtaaaat tggcgatagc cgtgggaaaa
     6061 tcaaagtatt tcggattggt acgctgatct ttgtcttggg atcgctgttg tgtgggttca
     6121 atcattcgct aggtatttta ttgttcgcac gggtggtaca agccattggt gctagtatga
     6181 ctatggctac aaatgccgga atcatcacgg aagtctttcc catacatgaa cgtggtcggg
     6241 cattgggagc aataggtgcg tttgtttcat taggctcgat tgctggacca ggtcttggcg
     6301 gcttgatttt gtcccaattt tcttgggcgt acattttttg gatcaatgta ccggtgggaa
     6361 tcgtaacgat gttgattgct gaaaaattct taccaaaaga tatcaccatg agcggccata
     6421 caatcgatgg agggggcttt gctgccattg cggctacgat tatcagcttt tttggagcaa
     6481 tctttttggg gcaagaaagt ggctttttcc atccagtccc ccttgtactg ttcgtaattt
     6541 cagtgattgc ctttgtcagc tttttaaaag ttgaaaagaa agcagcctct ccattgattt
     6601 ctttcggtat ttttaagaac aagattttta ccatgagctt gattacagcc ttgttgattt
     6661 tttcttccaa cttctttgtc aatgtagtga ttccttttta tctgcaaaat gctcgcgggt
     6721 tgagtcctag ctatgctggg ctgttgatga tggtctttcc tttgatgatg gtcgtcgggg
     6781 cgcctttaag cggctacctg accgaccggg ttggcccgga gattttggta ttagtaggct
     6841 tgggcttatt gtcggtaacc caggtcatgt atatgttttt gtcagtggac tctcctttgt
     6901 ggctatacat tgtcgctact gccatcatgg gtgccggcaa tgccttgttc cagtccccca
     6961 ataatacgat ggttatgagc tcggtcacta tcgaaaactt gggactggca ggctcgatga
     7021 attcctttgc ccgaaatttg gggatggtca gcgggatttc gctttctacg acggtcttat
     7081 atcaagcgat gtctgctaag atgggccagc aagtaactaa ctatatcgca aatcggccgg
     7141 atgtcttttt atatggaatg aagattacct ttttaggcag ctttgttttg tgttttgttg
     7201 cctttttcct gactatctgg cgtatcaaaa aacaaggagg tattcagaaa aatgtctgaa
     7261 aaaaccactg ttgaagaatt tttggaggcc tgcgtatggg tgagtgggat ttccatggat
     7321 gatggaagat gaagtgaact tctaaaagcc gaaaaactca agtattatct tcaaaatact
     7381 agtgctcaat gagatgcttg atttgatcac aagaagactg cgaaagccgc tggcaaccgc
     7441 aagctaggta tcccaccgat ggactacgtt ttagaggcta ctggttatga atacggagcc
     7501 aacgctctca tctgcataag aatacatcac ccagattatg taaagatttt cgatacttct
     7561 gtcaaaaaat cattaagata gataaatgat ttccgtctag tcaaattggt tcagaatgta
     7621 gacacacaga tggtaagaag tcactcacaa ttcgagaatg gacttgtcct atttgccgta
     7681 tacatcataa tcgaaacgtc aacgatagta tcaatatttt gaccaagggc tatgaataca
     7741 agcattgcct tagaaaacat caagaacctt aggaacaacg gggatagctt ggttaataag
     7801 agataccgct gtttaggctt gcaagtatac tcttttatca agaattccgt ggctttagtc
     7861 atgagaggct taatactatg aaaattttct ttagcatttt tgatttaggt tccttttcta
     7921 attataataa gatgaccact acagtaacct actgaaatat ataaacagcc actgtagtac
     7981 cattttcaaa gtagtctatg agaggagaat cttcattctt atgaacgctg gaattgcgga
     8041 tatgaattta ataaaaaaaa cccttaatga ttttacttcc aattcaatat caaaaggtac
     8101 tggtatcaat ttaagcacaa taaaaaagct gaaaagtggt gaaagatcag tggaaaagct
     8161 gaatctttta gatgctataa aaataacgga atttgctatg aaaaatggaa aagctgagat
     8221 tgaaatatgg agataattat cgtctagtga attacttgcc acttagctga atttaacgat
     8281 ccttggtgct tgaaggggga gattcttggg aatagagcat acttgcaagc ctatgtcttt
     8341 actaacaacg atatctctta ttaaccaagc tatccccgta gttctaaggc ttttactttt
     8401 atctaagcaa taatcgtatt caaaggaaat ttttgaccct tagaaagtct cattttatca
     8461 gacgtgagct taggcattgc tgaattttgt taattcggtt ttaggttgtg ctttgagcat
     8521 aatatgaaag tattctttat cacgatttca ttcatctaag gtaatgtgat gtgattctga
     8581 aattctttca aaggcagttt ttgcataagc tgacattaca tcatcaatga catgtttaca
     8641 atgtttcact actaaaataa gggggtaacc aagaagaaaa actgaatgat tatttgtatc
     8701 taattccatg gtatatcaac catttcctat atagactgat tatgacatgg attaaaataa
     8761 aaaggcacta tgtcttaatt gtcggttttc gagttaccga atggcattca tcacccacct
     8821 atagaggatg ggcgacttct gcctgaaata agttacacta cttataactt ctaataaaat
     8881 tagattgagt cattattatt taacatcaac gattttccag tttccatttt tttgtaatac
     8941 taatttgtac tgaaagtagc tagtggtttt tgatacatta tcaaggtatt ttatctttgt
     9001 actcactaga aaattttttc cgttttgtag ataaactgga ttctctaact ccgaaaactt
     9061 taagtcaata ttgattggtc gcatcgcacc attttcaaca taatactcca attctttttc
     9121 agaagctgat ggataaagtt taaaaaatgt ttctaaaaaa tcggtgattt cttccgttgt
     9181 tttggcatca atttctgaat cgttttctac ttgttttgct tcatattttg ccttgtctgg
     9241 ctttccaatc attgttggca aactagttac taaatgattc ctgttttcat cttcaaagat
     9301 tgtcactcga tatgcagaag aaattgattg cgtctttttt ccctctgtaa tatgttgctc
     9361 cactaaaaat gaaacgacaa attcttccga gtgtttttca acatctagaa tttttacaga
     9421 ttgaacttcg gaactcgtgg gaatatctgc tcgaaccata tcttggatta aagcgagacc
     9481 gttttctgta aggtactgtt cgagattact cattctcttt tcaattgctt ctttgttatt
     9541 tttccatgaa aaatattctt tcgcaaaatc ctctgtaaaa ctttcaacgc cagaagtatt
     9601 cactaccttc tcttttataa ccactttttc atgagttgta tgttgatcaa tggcggtgaa
     9661 atttttataa acgccaaaag caagactaca agacaataaa agccaaaggg caagcaccat
     9721 ttttcgatgc ttacccacgg atacaactcg ttcttttttc ttttttgggc tcttttcctt
     9781 ttgattccgt tcaattttta tcttcattct ttttcctctt ttctcttatt tgtatcggcc
     9841 agctccgata agatgctgcc gccaatagtt ttccgttaga ttcgtccacc ccactggatc
     9901 tcctgcatga aacatgcgat tctcccctgc gtaaatgccc acatgggtca cataagtacc
     9961 ggcatcatag gttgaatgaa agaaaactaa atcacctggt ttggcatctt ttagatcaat
    10021 atgagtcatg gcatcatatt gatcctgagc cacccgagga agtttcaggt caactttggc
    10081 ataacaccat tgggtcaagc cactacaatc aaaccccgtt tctggacttg agccaccaaa
    10141 cacataggcc gttccttcat acttaaatgc ctcatcaaaa atttcttgga ctattttgtc
    10201 atcaaactga gttgtagtta ggtattgctt cactaataaa cagtaaaaca tattgccata
    10261 attataccgc cacccaccat tttccttaat cgcgattggg ttggggtaat cgactttttg
    10321 accacctgat ttttcctttg aaaaagattc agctaaagca aaactatgct tcttcccgtt
    10381 tttcccgaca tgatctagat acccgccacc atagttatag gcctgaataa tactatcttg
    10441 atcacaccct agttctttgg aacgcttaac caaagacgca aaatagagac agccttgttt
    10501 gatggatgcc tcggtactta atgaattagg tggtaatccg gctgactcag aactttgcat
    10561 aacgtcttcc attgtgccac cagattccac ttgaataatc gccaaaagaa ttggaatata
    10621 ctctgttata tccgattctt tggcatactt ttccaccatt gcacggtgtt tcaatacttc
    10681 ttctgagaca ctagttccgc caggagaagt gccagaacta ccatttccct cactgtcttc
    10741 accaaacaac aaacccacac acatcaaaat acccataaaa gagatggtca gaaaagttaa
    10801 tgaaataaca cccactttct tcaagttcat tttttctcac ctgaccttga ttttggacga
    10861 tggttcattc ttttttgtac tttttgattg gtctgctttg gcagagtgga cctctgtttc
    10921 acttgttgga aagaattttt cttacttgct gattggcttt tcccttttga aatgatttct
    10981 tgactagtta gttttcgttt gatttcggga ttcagatttg ctctcacaat ccgctttggt
    11041 gcttcttttt tcagcatcat atctttctga ggttgagctg ctttatctat tggaatattc
    11101 gcccttcttt ttccctgacg atttgttgct tcactcagta tcttgcgttt ttcgtccatt
    11161 ttcgcatttc ttcgttgtcg ttgtttttct cgcaaatcca ctcgatccgc tttttcttgg
    11221 aacagtccgc gcttgaattc ttctggtgct tttttcgact tttcgattcc tttatggaga
    11281 ttgtatttca aattcgttgg cgtattcctt acctgatcct ttacttgttt agtcttatct
    11341 ttcaccaaag cttgggtatc caaaactttg ccgatttttc tcccagccaa attcattcgg
    11401 gattgtttct tattatttga aactggattc tccttagtta agtcagatag tatttcgtga
    11461 tcgttcggta atcgtgaatt ctttcgtaga gaagaaccgg atggcttaaa tttggatttt
    11521 gattgttcct ttgccaactt atttccgact gctgcaccac caccaaaagc caaagctcgt
    11581 cccacatttc gattgagttg ccgcaatttt cgattcatta acatttgcgg ttttcgcatg
    11641 acgcgtcttc ccattgactg gctatcatta ctctggaggt tgaacatact cataatgtcg
    11701 cccaatttga aatagatacc ggcaaaggtc acaatttgca gaaaagcaac catgaaaaat
    11761 ggataggttg ccgaaatatt gaaaaacatc gtggagatgc taaatgcagt cgtaatcacc
    11821 aaagtaacac ccgctcgcat cataatcgta ttgaataaac gaataatcgc cttctttcct
    11881 aaactttcat aagtcggcaa catggacaat aagaaactaa ttggcagaaa catcgcaaag
    11941 ataatgaaga gaatttgcga gaacaacata atccctgtta gaagaaaaac aaagaaggaa
    12001 atgccaatat tgaacaatac caaaaagacc acggtcccta aacggttcat ggtcttggta
    12061 atactgagat tcgcattgtc attgtcttca atctctgcct tgaccgcttc ttcccgatct
    12121 ttgcctttgt tttcatctgg actcacagat agaatcttgt tgacccggtc ttcaccaatt
    12181 tcttctatgt tggaatcatc aaattgcagt agtaaccaag gttgttggac ttgaatcgaa
    12241 aacaaactat cccgaatcaa atccacacta tcttttcctt ggctttctga attgggtaca
    12301 acgatctcgg ttccaagggt aagggccgct tcactaacat ctgagctaaa gtcattgatt
    12361 tttgtgatat aggtaggcgc ataagcaatg aacgaacccg atagtagaaa aatcatcaca
    12421 aaattaatca cggctcgaac tgctttcgtg gtttctcgtt ttaataatcc ggtatacgcc
    12481 acatacaccc ccagagctaa aatcatcaat aatagaaacc caaaataaaa tccggaggtc
    12541 tggagtccat tttcagtaat accagccaat gtttggatat tctttccaat actttcagcc
    12601 gtatccgaaa tgaaatctaa tttgtaagcc tcttgaacca cataacccgt ggcgttcgac
    12661 aaatacaaac tcaccgtcca aatgaaatta gtaatggcat aaagaccata catcacgctt
    12721 ttccctaagc catcacccca attccaaggc aaccaatccc aagagctatc cacaaagaaa
    12781 tctagttgat agttgttcag tgaatatttg gaatatagat ttcctgcttc aactgtatca
    12841 tcaactagcc ctgtcgcctc ggctaccgta ccaactaaac tcaatagaac tatcagagtg
    12901 agtatgctaa taaaaacgat tcccacaatc cgaaaaagtt tctttttcat cccctcactc
    12961 cattctctct tgaacaggtg gacgggtatc aaaggcatgg aagagttctt caaagactgg
    13021 atgtacctga accacgccta cccgaccata caaatcctgc atcaagcatt ggccattttc
    13081 caaatctcgt aggcgttttt gattgctttc atcttctcga tccaagccaa agaattccaa
    13141 ggttttcttg atttcatgaa tatcggtact gcgaaacgca aacttcaacc cgatattatt
    13201 cttcaagcgt tcatccagta aatcatcact attttgcgtg acaaagtaaa ccccggcatt
    13261 catagcccgc ccagcacgaa cgagcttatt cgataatgtt ttcccttgcg ctacttgaag
    13321 aaaactccac gcctcatcta agtctacaat tttgaagatt tctcgattac tatggataaa
    13381 gtccaaggca aaagtggaaa tgacgattag catggaaaca ctaagcaatt ccatggtggt
    13441 atattcttca aaagtggttt ctgcatctgg taaaaccaaa tccgctactt gaatgatatt
    13501 taactgccta tctaaactaa tcgactgggt aatcgaacca tctgagaaaa gcaaatgggc
    13561 aaaatcataa tcggtaaagg actcgatgtg atccgcgata ttttccgcaa ctggtgagcc
    13621 ttcttttcga agctcattaa ttacttgtaa taatccccgt tgattgcttt gggtaaccgt
    13681 ccgaatggcc ttacgcaaca ctggaaactt ctccccatct cgactagaaa ttcctgttaa
    13741 aaaggtcaga atatcaattg ctagactttc agaatccttc tttttctcca taatcacata
    13801 aggatcaagt aatccttgat tttttggctt actagttaag ttgagaatat tgatttcatc
    13861 cgcaatttct ggcaaggttt ctttccagcc accccgttcc ccttttggat cgacaatcac
    13921 agcttgtcca ccaaaaagga cggcgtaata aactaagaga ttgttactaa aggactttcc
    13981 gccaccgagt gaaccgagga atgccgctgc tagcgcattg gtaactgaac ccttgacccc
    14041 ttgtgaggcc aatgccggtt tcaggtaaac attgcgcccc gtatctacgt tataaccaaa
    14101 gtaaatgcct tccaactccc ctaacatctg agtggcgcca aaaccaagtc cggcgagaaa
    14161 atcagacgta acatactgga tataatcatt catgtatcgc ttactagaag gtaagaattc
    14221 ttcatgtagc cccatcatat cgccaaaagg ccggactagt tttacattgg tatcatcata
    14281 aaaatctagc acttcatcac accggcgctt tagttcatct actgattcgg cacttactcg
    14341 aaccacatag ctcagtttgt acatggattc tttggactga tccaaggtag tttccaattc
    14401 atctacggaa tccaatgcat ctaagacatt ggaatttgtt tcattgtcag attgataggc
    14461 atggttgtcc aagtctttta attccttttt cttattgcga acggtagcaa gtgccttttt
    14521 gttcgtcaca atctccacat tcatactagt gtcaattggg aatgtaaatt gttgttgctg
    14581 gtaatagaaa agttctgagg agggaaactc catttccccc acaattgtat taattgttaa
    14641 gtacgctaca tatgattcat gattctcatg ttccatgcat aagtaccggg gcttttcttc
    14701 aatcaaacaa cgactgggac gtaataagtc gtaacgtttc accaaagttt ccgacttcag
    14761 ctttttcttt ggtagctgaa attcatattc ttcaaatggt gtaccctttt cgccatagat
    14821 atgttcaatc aaatacatca gatcactcgg tgtgactcgt ctgactttaa atcttcgagc
    14881 caatttactt tccattagtt tttcaagctt ggtatatcgg cgaatttctt cattggataa
    14941 ggaaacaaaa tcgcccatca aatgatgatt cactccatag acaaattctt gaaagccgga
    15001 gaagaaagat ttcttgagat tctttagatt gacctcttca tctgtcgcaa tcagtttgaa
    15061 gccaataaaa aagcgataat caatctgact atcgccaatc atggatacta atgcctctgt
    15121 ctgtaaatca attcgttgtt tcgctacttc tgttaatcgc ccggtaattt ccttttttga
    15181 tcgttcttgc gtggcacgaa tactactttc tgtggcaatt tgtaaggcat gaatcttgcc
    15241 ttcacgattt tgcgcaatca attgacgaaa gttatcgtgg acttgatatt tctgttcagg
    15301 tgacaaaaag gagtaattgt aaggtattaa ctcatagtag gcaaaacatt ctccctcttg
    15361 attaaagaca agattatttt caatatactt aatcgggtac atagttcaca ctccttacca
    15421 gagtaatggg ttcgtcccat cgtttcttct gttctttgac tttctttcct gcgaaagtga
    15481 ccttaaatcg taagtgatag ctaataaaag atcgtaaaaa tcccaatggt ttcttaccgt
    15541 caaacgtttt ttgcgacatg aaccaagtaa ctgccaccgg tatacctaag tattttaaaa
    15601 aggccccctc tatcatagat agtggaggca catgggcaaa tacgatgaca aacagcaagg
    15661 ataaaacaaa ccaagccatc tggttaaaag tcacaggaaa aggcagttga aagtcattaa
    15721 ttgcataaat gaccttttca actgcccaaa tactggtgta gctttttatt ttcttcatca
    15781 aatcattcct ttaaaaagaa ggatagttta gaaatcaact acccttcaat aattttgtta
    15841 atatggatac tcaaaaacac ctcgactcgt taccaaataa ttgcctccaa tctccaagtc
    15901 tctaccacac gcatcaaaat caatatacgt cttcaagtgt tctggtactt ctccaaaatc
    15961 accagcttct acaatcaaga aatatgctac atcactcata tcatcgcaat ctggataata
    16021 gataatatca tccacatgct ctaccatctc ctcaaaagaa ttgaagaaag catgttgaat
    16081 ctcagaagca acttcaccaa ctggcgttcc ttcaagttcc tccgctaagc cacacaaccg
    16141 attaatttcc tcaattggcg tatactcatc aatctcaaag ggaagttcat aatcatgaat
    16201 tgcatattcc tcgtattcgt catttaaccc aattcgttct ttcacttcat caaaatcgac
    16261 aggtggggta aaccacgccc ccaccaattc accttcgtta tatttcccga ggttcgcaat
    16321 ataaacacgc atctgttcca tcgtgcttcc cccttacgca ccgacaattc ggttaaacaa
    16381 actgagtaag acatccttca ccccagaagc attaaagacc aatccgaccg caatcaaagc
    16441 aatcaccaaa aagccaatca gtttggaaaa ctcccgctta aatcctaaaa acaaaccaat
    16501 gaccacaatt gccagtaaga ctaaggattg ggcattggtt aaaaaccatt
//
LOCUS       DACGMI010000063        16334 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.065, whole genome shotgun sequence.
ACCESSION   DACGMI010000063 DACGMI010000000
VERSION     DACGMI010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.065"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(119..775)
                     /locus_tag="IXT46_002335"
     CDS             complement(119..775)
                     /locus_tag="IXT46_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAQ4948232.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            968..1246
                     /locus_tag="IXT46_002336"
     CDS             968..1246
                     /locus_tag="IXT46_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948233.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            1265..2473
                     /locus_tag="IXT46_002337"
     CDS             1265..2473
                     /locus_tag="IXT46_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4948234.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(2621..2986)
                     /locus_tag="IXT46_002338"
     CDS             complement(2621..2986)
                     /locus_tag="IXT46_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAQ4948235.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(3133..3906)
                     /locus_tag="IXT46_002339"
     CDS             complement(3133..3906)
                     /locus_tag="IXT46_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4948236.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            complement(4080..4940)
                     /locus_tag="IXT46_002340"
     CDS             complement(4080..4940)
                     /locus_tag="IXT46_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAQ4948237.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            complement(4940..6358)
                     /locus_tag="IXT46_002341"
     CDS             complement(4940..6358)
                     /locus_tag="IXT46_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4948238.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            complement(6415..6864)
                     /locus_tag="IXT46_002342"
     CDS             complement(6415..6864)
                     /locus_tag="IXT46_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4948239.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            complement(7309..7572)
                     /locus_tag="IXT46_002343"
     CDS             complement(7309..7572)
                     /locus_tag="IXT46_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAQ4948240.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            complement(7671..8966)
                     /locus_tag="IXT46_002344"
     CDS             complement(7671..8966)
                     /locus_tag="IXT46_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAQ4948241.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            complement(8963..10234)
                     /locus_tag="IXT46_002345"
     CDS             complement(8963..10234)
                     /locus_tag="IXT46_002345"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAQ4948242.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            complement(10399..11268)
                     /locus_tag="IXT46_002346"
     CDS             complement(10399..11268)
                     /locus_tag="IXT46_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAQ4948243.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            complement(11560..13170)
                     /locus_tag="IXT46_002347"
     CDS             complement(11560..13170)
                     /locus_tag="IXT46_002347"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAQ4948244.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(14363..15703)
                     /gene="glnA"
                     /locus_tag="IXT46_002348"
     CDS             complement(14363..15703)
                     /gene="glnA"
                     /locus_tag="IXT46_002348"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAQ4948245.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(15731..16123)
                     /locus_tag="IXT46_002349"
     CDS             complement(15731..16123)
                     /locus_tag="IXT46_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4948246.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         4660 a         3462 c         2777 g         5435 t
ORIGIN      
        1 tgttcaatca gctgaccctc ggtattagct caaaaaacgg caaaatatga ggaactattt
       61 ttccgtttgt ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttgttcatc
      121 aaaagataat attgtcttct aacaagtcca tattcaaaat aacgatatga tggtctttaa
      181 cggtgataat accatctttt ttcagttgtt ttaaaattct gtttacactg ctagcagttg
      241 agatgccaca aaatttggcg atttcttcat tcgtgatcga aaaatcgatc agcatccctt
      301 cttctgtccg cacaccgaat aaatcatata attcgtaaag ttgcgtacaa acagctccca
      361 gctttccgtt taatagcatt tgctgcattt ttttcatcga ataaagcaga cgatagcggt
      421 aatactcttt tacatagtgt tgtagctttg ggtcttggtt gatattttgc caaaagcgca
      481 cacgattgat tcgataaaac tctgcatatt ctgattcaac tcgaatatta tacggcgaat
      541 cgatgaattg tgaatattcg tcttttaaaa gagagacgat ttcaagatct ttgatatagc
      601 gaaggttaaa ttctctccca tcatttgaaa taacacttgc ttttaccgtt ccctctttca
      661 agatatacgt atgggaatct tccatccctt cgaatgtcaa atatttatga tatcctttgc
      721 gtataatcgg aaaatcattt ttatccaaat attcctttaa gactctacta tccaatgatg
      781 ctcccccatc caaactttca tctaaaaaga tcatacagta ctttaaaact ttttaaagtc
      841 caaaggtatt ttactaatga tattaacatt tgttaagtac ctttttccat cacttatgcg
      901 atttttttcc ttttttttat tcgttatact gcagaagtaa aattttttaa gaatagaggg
      961 aaaaaacatg aattactgga tgaacacaat cattaatcga ttagaaacag catatcaaac
     1021 aagatttgat atgaaagctt ctttagtctt tttaaatgat gcgtatcaaa actcgatcga
     1081 attgatcaaa gcagtggatg agaatccaac aaacgaatgc gaagaatttt taaatctgtt
     1141 tatgtctaca agagatttat ttattcgcca acttgttgat cgctatccat ccaattatca
     1201 cgatgtagaa gttcaaatac aaaaattaaa agcatattca gcttaagggg aatgtataac
     1261 atacatggaa aagaaattat ttaataaata ttttattgga atcacattga tcaattttat
     1321 tgtctacctg atttattatc tgttgatggt catcatggca gtcattgcgc aagacacctt
     1381 acacgccagc ttgagccaag caggttttgc ttctgggatc tatatcatcg gaacattgct
     1441 ggcacgctta ttcatgggga aacagttaga actatttggt cggaagttta ccttaagagg
     1501 cggcgcgatc ttctatctcc tttcaacatt agcatatctt tatacgccaa ctatcggggc
     1561 attgtattta gttcgattct tgaatggatt cggctacggt acagtttcta cagctacaaa
     1621 tgctatcgtt actgcatata tccctgcatc taaaaaaggg gaaggcatca attattatgg
     1681 attaagtact agtttagctg ccgctgttgg gccattttta ggaatgattt tgctgaatat
     1741 gactgatttt cgtttcatta tctggttttc aattgtactg gtcttctttg ttacgattgc
     1801 ctgccttgtc tttcctgtaa aaaatattcc attatctgaa gaacaaaaaa tatctcttcg
     1861 ctcatggaat atcaatagtt ttattgaaaa gaaagcactt ttcattacag gaattgcctt
     1921 tttgatgggt ctttcttatt caagtgtttt atcattttta tcttcttata caaaagtaat
     1981 ccacttagtt gctgctgggt catttttctt cgtcgtatat gctttggtca tcacatttac
     2041 acgtccattg actggaagga ttttcgatgt caaaggagaa caatacgtga tgtatcctag
     2101 ctatttattc ttaacagcag gattattttt actgagtgta acgacgaata gtgtgacatt
     2161 gcttatctct ggagcattag tcggcctagg ttatggtacg tttatgtcaa atggacaggc
     2221 tgtttgttta aaaatcgtcc gcgaacatcg aatcagtatt gctttatcta cctactttat
     2281 tggtttagac ctaggcttag gcgttggtcc ttatttgatg gggatgctaa aatctcttac
     2341 ttcatttaga ggattgtatg tgattgccgg agtcattcca ttgatatgta cagcactcta
     2401 tcttgttaat ggccgaaaac atagtcatga agcagagggc gaattgattg aatcattgaa
     2461 aaatgaaatt tgatcttgat gaatagataa aaaaaaccgt tcagatctga aaataatctg
     2521 agcggttttt tgagtaaaaa tagtttatga ttattcttaa ttaaacatct atttattttt
     2581 aaagctttca tttatcgata agaatagttt aactgttgat ttattccatt ttccgttcat
     2641 ctggtacgat gccttgactt agcaaccact tgtggaagaa ccattctgcc acaccgatca
     2701 atagagcagg aatcaatact ttcatccaaa tatcgactgt atcattcata aaatatagat
     2761 agagccacaa gataactgca gctgaaccag catctgcgat cgtcgctgcg atgttcccta
     2821 ctttacgtaa gatcaacaga tcccctagca catagatcat gactacaata attaccccaa
     2881 caatcgttga atccataaag ctaacaccgt ataaacctgt cagcacgacc cacagaatcg
     2941 cccagatcat gattgccttc actaccaacg ccttcacatg tttcattttc tgcactcctt
     3001 tctcctggat aaaaaagtaa gattatctaa caagataacc ttttcattat tataccatcg
     3061 gctgagagaa gcgagcaaag ataaggtcct atctaaaaat gaggaagcca cttagaacat
     3121 tcacgtaata atttatccgt acagacattc gatatggtgt tcctttactt tcgcatactg
     3181 ttcttttgtc agttctttac ttgtcaccag ataatcgatt tcatgaaaag caatggcttg
     3241 atgcatgaat ttatgtgcaa ttttttgctg tgtaactaaa acggcaagcc ggtctgattg
     3301 ttttctaaaa gcttttttga ccattgcctc tccttcatga gtttctgtta ctccttggct
     3361 gaaatctagc ccgcgacaac tcattatcgc taaatccgca taatatgaca atgcatcgtt
     3421 ataggctttt gaaccgttga ttgttgctcg tttcggaaca attgcccctc ccaatacaga
     3481 tacttttgcc gttgtatatt cactcaacat agcagctgtg acgatgccat tcgtaatgat
     3541 ctgcaaacca tcaaatcttg ctaggtttct gactaagtgt aaagaggttg tactggaatc
     3601 caagaataag accatatcat ctcgaatcaa agaagaagct gtatctgcaa tcttacgttt
     3661 ttctgtttct tcttctaatt tggtgatctt catcaggtaa ggcacgtcaa tttttcgatt
     3721 gtcaataagc atggcgccac cgcgaactct acggatcaat ccactttttt ccagaaaaac
     3781 aaggtcacgt ttaatcgtgg cttcgctata atttactaac tcgatcaaat cggtgactct
     3841 tgcaaattgg ttgtttttta gataattcac aatctcctgc tgtctattct ccacttcatt
     3901 caacataaaa tcaccccatt tactttatat agtaacagga aaaaagaggt tgtgacagaa
     3961 gtgattggct tcgagaaata agaagaaatt tttcgaaaaa actacttctg aacatcgtgt
     4021 gtggttaaga gggtatgaca agactattgt cataccctct tgaccacaca tttttatttt
     4081 tagtataaac tagccttgcc tactgtgttc aaaatttcca ttttatgttt gaccacttct
     4141 tgtacctttt tattagctgc tggataaatt gcattcggct cgtacatcga tggattttca
     4201 ctcaatattt ctctcaaagc attgaaaaag acgcttttaa gatctgagct caaattcact
     4261 ttggcaactc cgtattttac tgcttcgctg acttctgcgt ccggattacc tgaaccgcca
     4321 tgtaaaacaa atggaagatc gatttgttgg ttcaattctt tcagtaagtc gatatttaat
     4381 tttggagttc tgtttttcgg atacaagcca tgcgctgttc caattgctac agcaagtgta
     4441 tcgattcctg tttctttcac aaaaatcttc gcttgatcag gatctgtata aatgattgtt
     4501 tcagcacctc cttcagcaga accattattc ccaatcgttc caagctcagc ctccactgag
     4561 acatttaccg catgagctaa cgcaaccact tttttcgtaa tctgtacatt gtcgtcgaat
     4621 gatttcaaag acgcatcgat catcacggaa gaatagccgt ttcgaatcgc ccgtaagaca
     4681 tcttctatcg taccgccatg atccaagtgg ataacgatcg gcagtttact tgtataagca
     4741 taggctctta ctgccgcaac aaactcatca cttaaatagg cgatttcatc aggatgaatt
     4801 tctaagatta ctggtgcttc taatctctct gcttcttcga tgattgcttt catcatatca
     4861 tagctgcaaa tattgaaggc tggtactgca aattgattct ctttagccac tttcaataac
     4921 tctttcattg tatataacat tacgcttcca cctcatttgt tagattttca tttttcgtcc
     4981 acttgtcttg ttttttctct ttcactgttt ttttcaatag tccaagcata aaggctgtag
     5041 tgactgtacc tgatgcaatt gccaagacat acataggtaa attgttcata acatttggaa
     5101 ttagcatcac ccaaatccct ccatgaggtg ccattgaagt aactcctact gccatggaaa
     5161 tccctgcagc gactgctgaa cctgtcatca aactaggtat cacgcggatc gggtcagata
     5221 ccgcaaacgg tatagcacct tctgtaatat acgaagcgcc taaaatccag catgattgac
     5281 ctgaagtccg ttcttctttg gtaaatttat gtttgaataa taaagtggct aaagcaatac
     5341 ctaggggagg tgtcattcct gcagccatac aagcagcaat cggtgcattt actccagctg
     5401 acatcaaacc gatcgagaaa gtcgaagtcg atttattgat cggcccaccc atatcagctg
     5461 ccatcatgat cccgataagt aatccgaaca atagcccgga tgtatttccc aagctattca
     5521 gccaatttgt caaagcatcc aacacccatg tgatcggttg ttcaatcaca aataccatca
     5581 aaagcccaat aattaagatc gataaaaagg ggacgacaat cagctgataa atagcagaaa
     5641 attctttttt tacgctaatt ttatttgcca gaaaatcaca gatataccct gctagcacgc
     5701 caccaatcat tccgccaaga aaacctgaac cacctgtaga ggccagtaat ccggcaacaa
     5761 ttcctggggc aaaacctgct tttccagcaa tcgatgtagc aatccccgcg cctaacgcag
     5821 gaaccatcat ggcaaacgct gtatctcctc cgatccttga aaatgcagct gctaacacat
     5881 tatagtctgc tgagttggga tcagccgctg taatcccaaa ggcaaaactc agtgcgatga
     5941 tgattccgcc tgcgatcaca aatggaagca tgtaattcac accattcatg aaatgattat
     6001 agattgtcgg ctttttctca tttgcagctg gttctttttc attagacaca acgaatacgc
     6061 caatatctct caatgcttcg tctattacta cttgcggttc tttgattgct cggcttgtag
     6121 agacacgctt tacttttttc ccggcaaatc ggtccaattc gatttcttta tctactgcaa
     6181 gaatgattgc atctgcctct ttgatttctt gttcagataa ctgattttct gtttttacac
     6241 cttgtgtttc gaattttgct tgatggttta gatttcttgc tgttacttct aatttttctg
     6301 ccgacatata agtatgagca attccagtcg ggcaagcagt tacaccaacg attttcatga
     6361 ttattttcct cctttttctt cactatcgat actcggacaa agactctact attttcattc
     6421 ttgactaatc tgtctgatga tatctgctgg cgtagtggct tcttttattc cctttctaaa
     6481 atctgcattc atcaatcgtc tggagagtgt gctgagaatc tctagatgca tatctgctga
     6541 tttttcagga actacgatgg caaaaatata ttcaattggc atttcatcta tcccgctata
     6601 gtccgttaat ttggctgtat gaaaaaaaca cagtgctggt tttgtcacat atttgctttt
     6661 tgcatgggga atcccaaatc catcttctat tcctgtggag atctcctcct ctcgtttgaa
     6721 tagtgcctta acgacttttt gaacatttct taccttattt gtttttttca acacatcccc
     6781 tattcgctca aataatgatc cttttgaatc tatcgatgga tcgaaaacaa tcagttcttc
     6841 tgcgatcaat tgatcaaacc tcataaaaaa cctctccccc acaaaaaatg ttaacgtttt
     6901 cttggaactg aggtcagtat agcatcgcta gctgtaccgt tcaatattat gaatgaacag
     6961 aggaaaaaga cccatcatcc gcgtgtataa gtcattaaaa tgaacgatct agctcacaaa
     7021 caatcgcaag tctataacaa aacaaaaagc cttccttgaa aggaaagctt agcttctaat
     7081 tttaggtaaa tggtttttta cttcgaaata acccctcttc atttcgttaa tataaggtgt
     7141 ttttatcaag tggataatta aaactatata ctagtttttc attgttttgt gcattatgat
     7201 cctacgactt tttcagcatc aaacgaagtt ttaaattggc aaaaaacata aaaaaacaga
     7261 ctatccctat cagatagtct gctaaacgtt gagttatcag cgtttttatt attccgcagc
     7321 gtttgcgtct ttgagaccgt attttttgtt gaaacggtcc acacgtccgt ctgcttgtgt
     7381 gaatttttga cgtccagtgt agaatggatg tgagtcagaa gttacttcga cacggatgac
     7441 tgggtatgta ttaccgtctt cccattcaac tgtttcttgt gaagtttttg ttgaacctga
     7501 caagaatttg aaaccagttg ttgaatccat gaatactact gggtggtaat ctggatggat
     7561 gttttctttc atgatttttt cgctcctttg ccctgctcca tttgctgaac cagagttgat
     7621 ttgtcgattt acaacattaa catcttaaca tgtttcagtc aaggttgcaa ttatcttttc
     7681 agatttctgg tcggattttt tttaccaaag gagacatctt gaaattcttt gaaaaattgc
     7741 tgattgtttt ttgttttacg caaaaagcgg atcagttgtt ccgtatattc taatgaatct
     7801 ccagtcatat tttttcgaag tttccaaatt tcttctaatt cttcacttgg catcaataat
     7861 tcttcttttc gggtacctga ttttttgata tcgatggctg ggaagatccg acgttcagat
     7921 aattcacgtg aaagttgtaa ttctagattt ccagttcctt tgaattcttc atagatcacg
     7981 tcatccatac ggcttcctgt atcgactaaa gcggtcgcta aaatcgtcaa actgccacct
     8041 tcttcgatgt ttcttgctgc cccgaaaaat ttcttaggtt tatacaatgc ggctgggtca
     8101 atcccgccac tcaatgtacg tccgcttggt ggaacgacta agttataggc ccgagcaagt
     8161 ctagtaatac tatccatcaa gataacgaca tctcgtttat cttcgactaa acgcattgcg
     8221 cgttccaata ctaattcaga aactcgagta tggttttgcg gctgcagatc aaatgtagaa
     8281 gataccacgt cgcctttcac gcttcgttct agatccgtta cttcttccgg tcgttcatca
     8341 atcagtagaa cgattaattc tacttccgga tagttttcgg tgataccatt tgcgatttct
     8401 tttaatacag aagttttccc tgcttttggc ggtgcgacga tcaatccacg ctgaccaaaa
     8461 ccgattggag aaaagatatc gatcattcgg gtagatagtc tttgcggtgt tgtttccagt
     8521 tgaagctgtc tttgcggata aagaggtgtt aaggctggaa aatgcggacg ttcttttgct
     8581 tcttccggat cttttccatt aacgctttcc acgtgcatca aaccataata acgttccgat
     8641 tctttaggtg gacgggcttt tcctgccact ttgtccccat ttctcaaact gaatcgtctg
     8701 atttgtgagg cagaaatata gatatcttct gcacttggtc cataattgat tggccgtaaa
     8761 aaaccgtaac catcttgacc aacgatatcc aatattcctt ccatataata aaatccttgt
     8821 ttctctgctt gtgcacgaat cacagctaga gataattcct ttttattcat cttactgtaa
     8881 taaggaattt taaattcttt ggcataacta taaacttctt ttaacgtttt gttctctagt
     8941 tctgccattg tcaaataatc gctcattcag ctcccacttc ctctatcatt tcaattgatg
     9001 cccctaaggc tgttagtttc tcgataatat gatcataacc gcgtaagata taatctacat
     9061 tgtaaatcgt cgttgtccct tctgccaata gtccagcaat cactaaacaa gcacctgccc
     9121 gaagatcaga agccacgact tctgtgccgt gaagtttatt tggaccattc acgatgatca
     9181 tatttccttc cacggtaata tcagcgccca ttcgtgctag ttccggcaca tggttcacac
     9241 gtttcgcata gatcgtatcg atgatttctg aagtgcctgt agtcatcaat agtaacgcag
     9301 taagtggctg ctgcagatct gtggcaaatc ctggataagg ataggtcatg atgtttgcgg
     9361 gttttaattc tttcgagggg taaacttcga tttcatcttc gctgattttc atatggacac
     9421 caatttcctg caattttgct ataaagcttt ccaaatgttc aaagatcaca tttttcactt
     9481 tgataccatt tcctactgca gctgctaatg ctagataggt tcctgcttcg atgcggtcag
     9541 gaatcatgaa atgccgacag ccatgtaatg tttcgactcc ttcgatacgg atcacatctg
     9601 tacccgctcc tcgaactttt gcccccatat tattcagtaa agttgccaca tctatgattt
     9661 ccggttctcg tgcagcgttt tcaattactg tctgtccttt tgcttttaca gcagctaaca
     9721 tcacattgat cgttgctccg actgaaacca cgtccatgaa aatccgattg ccacgcaatc
     9781 ctttattttc tgtccgtaaa tacatggcac catgttcatt tgtcacttca gcacctagag
     9841 cttcaaatcc tttgacgtgt aggtcaatcg gtctagggcc taaataacag ccacctggca
     9901 ggcctactac cgcttcgcca aatttaccaa gcagtgttcc cataaaataa taagaagcac
     9961 gcaaactatt gatttttccg tgcggcatcg gaatcgatac gacttctcga ggatcgattt
    10021 ctagtatgtt gttggaaaaa tggacagttg cgcccatgat ctctaaaatt tcaattaatg
    10081 aatgaacatc ttgtatgtcc ggcacacctt ccaagatcac tggggaatca gctaagattg
    10141 cagctggaat caatgcgact gcactatttt ttgcaccgct gatcgttact tcaccagcta
    10201 aaggtcggtt tcctttgatt acgatttttt tcatctgttt ccaccttgtt tattaatctt
    10261 ttttcatgga tatgcttgta ttttatcata gataaaaaaa agaaacgagc atggtctgcc
    10321 gttttaagta aaaaagaatg gagagcgact tcaaaagtcg ttctccattc ctatatatcg
    10381 tatctgttat gtggatgctt acgctttgtt agctgaaccg aaccagtcga tatgagattt
    10441 agcatcttca acgattgctg ctttacctgg agctaataat ttacgagggt cgaatccttt
    10501 accttcttta tctttaccag cttcgatata tttacgagta gctgcagcaa atgataattg
    10561 gaattcagtg ttaacattta cttttgagat acccattgag atagcttttt cgatttgatc
    10621 ttgaggaata cctgatccgc catgtaatac taaaggcatg tctggaccta cagcatcagc
    10681 aattgcttgt aagtggtcaa aagctaatcc tttccagttt tctggatatt gaccatggat
    10741 gttaccgata ccgcaagcta agtagtcgat acctgtagca accatttgtt tgcattcttc
    10801 aatatcagct aattcgccgt taccgatgat tccgtcttct tctccgccga ttgaaccaac
    10861 ttcacattca actgagatac cttttgcatg tgctttttca acaacgtctt tagctaattt
    10921 caagttttct tcaaatggta gatgtgaacc atcgaacatt actgaagtat agcctaattc
    10981 gatacattcc aaagcagctt cgtaatcacc atggtctaag tggatagcaa ctggaacagt
    11041 gatgttcatt gcttcaacta aatcagtgat taaatcttta cagattttgt aaccacccat
    11101 gtatttagct gcacccattg atgtttggat aagtactggt gcttgttttg cttcagccgc
    11161 ttcaaggatt gcttgagtcc attccaagtt gtttgtgttg aatccgccga cagcgtaacc
    11221 gcctttacga gcagctttta aaaattcagc tcctgatact actggcataa taaaattcct
    11281 cctaagtttt gtaaaactaa atttgttaag acaattctta accaacgacc ctattttacc
    11341 aaacatttcg gtagttttct actaaaatca atgaaaatga aaattttcaa gaagtttttt
    11401 gcaaaaaata aaatatccaa tagcgcttta atcgaaaaaa gtcttttgct ttctatcttt
    11461 tttcctacaa ataataacaa atcagaaaaa gagaaaagtg acaagaaaat tgcttatccc
    11521 cttctcttgc tacttttctc tttctatcaa gttcaaaaat tattttgttt cgtgatctgc
    11581 taatgatgct ccgacaaatg ctttgattaa tttttgcggg cgatttggac gagaaatcaa
    11641 ttctgggtgg aattggcatc ccacaaagaa ttttttctct ggcagctcta cgatttctac
    11701 taaacggtta tctggtgaga cacctgaaaa gactagccct tgttcttcaa acaattgacg
    11761 atatttgtta ttgaactcat agcggtgacg gtgacgttct tgcacaacat cggctccatc
    11821 atatgcttca gccgtcttcg ttcctttttt gattttacat gggtataatc caaggcgtaa
    11881 agttccaccc aaattctcga tgttttcctg atcagccatt aaatcaataa tattgtttgc
    11941 tgtatctgga ttcgtttcag ctgatgacgc atcttctaat ccaacgacgt tacgtgcaaa
    12001 ttcgacacaa gccatctgca taccaagaca aatacctaaa aacggaacgt cattttcgcg
    12061 agcataacga atcgcttcga ttttcccttc tactccgcga tcaccaaatc caccaggaac
    12121 caagattcca tctgcgtctt tcaaacgttc ttctacattt tctctcgtta attcttgtgc
    12181 tttgatccaa tcgatctcga tgtctgaatt ataggcgaaa ccagaatgtt tcaatgcttc
    12241 aactactgag atatatgcat ctggtaactc gacatattta ccgacaagcg caatccgtac
    12301 ttttttcttc aagttcaaga cacgttcttc taattctttc cattctgtca tgtctgcttc
    12361 tggtgtatct agttttaaat ggtcgcaaac aatttgatcc attccttgtg cttgtaaaac
    12421 taatgggatg gagtaaagtg tatctacatc tggcgactcg ataactgctt ctggttcgac
    12481 atcacaaaat tgtgccaatt tgtttttcac gctttgagaa acaggttgct ctgtacgtac
    12541 caccaaaata ttcggttgga tacctaaacc acgtagctct tttacactgt gctgcgttgg
    12601 tttagttttc atttctccag cagctttcaa gtaaggaatc aatgttgtat ggatatacat
    12661 aacattatct gtaccgacat ctgctttcat ttgacgaagt gcttcaagga atggcaaaga
    12721 ttctatatcc cctactgttc cccctacttc tgtaatgatc acatctgaat cagtcatttt
    12781 agctgctcgc atgatttttt ctttgatctc atttgtaata tgaggaataa cttgaacagt
    12841 tgctcccaag tattcgccct tacgttcttt acgcaaaact tcagaataga tttttcctgt
    12901 cgtcacgttg gagtatttgt tcaaattgat gtcaataaaa cgttcgtagt ggcccagatc
    12961 caaatctgtt tcagcaccat catctgttac gaatacttct ccgtgctgat atgggctcat
    13021 cgtccccgga tccacgttga tgtatggatc aaatttttgg atagttactt ttaagccgcg
    13081 gtttttcaat aagcgtccta aagaagctgc aacaatccct tttccgattg atgaaacgac
    13141 accgccggtc acaaaaatat attttgtcat aagttcaaaa actccttttt aatttatgtg
    13201 caggaaaagt ctcagacaat aaacaaagct ccctattctt caataagaat agggagccga
    13261 aatttctgta aacttctgac cctctaaaag ggtgcccaag gtgtataata caagctgact
    13321 aagggaaagt caagtactca aatgaatact atccgcttac aattttttct ttttcgatat
    13381 cctttgagaa attatttctt aagtccttta tgagtgcaaa aaaaatttaa cccacataat
    13441 aagcttgata taaacatagc taacgttaaa cctaagcaaa tcagaaaatc gttactgaaa
    13501 aattttaagt gaaataatag ataaaaaaat aaaacaaaca ttatgataga taatatccca
    13561 cctaacaaag aactactttt tcctacttgc agcaacagtt tatatagctt atcgtagaaa
    13621 caatcttttt ctttcaccct tatttacctc ctttacgtaa aaaacgtagt ccacagttct
    13681 cggatttttg gcatatcttt tctattaaat aatatcaaaa acaaaacaat tccactaatt
    13741 ttttcaaaga tgaccttttt ttcaacaaaa gtgccttgta gggattcatt gaaggtaacg
    13801 aatcacataa gtaaaaaata aggagatgcg acaaaagtcg tgcctcctta tttctaaata
    13861 aacggtgttc tcctgccaac tcctcggtca caagtcacaa tatccatcaa acatgagaag
    13921 ctgtttttga aattatttct tgtgattcgg agttaaatgg taggctcaca acctctggat
    13981 aaacggtatt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtagaaa
    14041 gccattttca caaaattttt cttaatactc gaaactaaac gtctttttca aaacctcttg
    14101 gtaaacggtg ttcaaaagct tgcatctgcg gtaataagtt cagccaattc aaaaacaaga
    14161 aaagctgttt ttgcttggct attcttatta cttgttgcag ggcagctttt tcacaacctc
    14221 tccactaaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac ggcaaaatat
    14281 gaggaactat ttttccgtta gtttctctaa tactcaggtc aaaacgctga tttcacagcc
    14341 tctaattcac ggtattcctg ttttaataaa gttctagata ttgttctctt tcccactcgg
    14401 aaacagtttg tctgaatgcc gcccattcga gacgttttgc ttcaacaaaa tttgagaaga
    14461 tatgttgtcc taatgcgtca atcattacat tatccttacg caattctttg atagcattat
    14521 ggatagttga aggtaagtcc tggatatgtg cagcttctct ttcttcctca tccattacat
    14581 aaatgttacg gtcaacagct gctggcggtg tgatctgatt acggataccg tctagtcctg
    14641 cttgcaacaa tactgccatt gccaagtatg ggtttgcaga tggatcaact gaccgcaatt
    14701 ccaaacgtgt ggataaaccg cgagattctg gtacacgtac taatggcgaa cgattacggc
    14761 cactccatgc gacataaaca ggcgcttcat aacctggaac gagacgttta taagaattga
    14821 ctgttggatt gcaaacggct gtgtaggcac gagcatgttt cagcaaacca cctaagaaat
    14881 gataagctgt ttcacttagt tccaattcac cgtctttatc atagaaaaca tttccttcat
    14941 cattgaacaa agacatattg caatgcatac cagaaccatt gatcccaaat aacggtttcg
    15001 gcatgaaagt cgcgtgaagt ccatgcttgc gtgcaatcgt tttgacaacg agcttgaagg
    15061 tttggatatt atcacaagca tctaccacat ctgcatattt aaagtcaatt tcatgctgtc
    15121 ctggcgctac ttcatgatgt gaagcttcca cttcaaagcc tagactttct aattccaaca
    15181 cgatgtcacg gcggcaattt tcacctaaat ctgttggtgc aaaatcaaaa taaccacctt
    15241 tatcattcaa ggtcgttgtg atcccaccgt cttcgtctaa tttaaataag aagaattctg
    15301 gttcaggtcc taaattgaaa gaggtaaaac caaggtcgcg catatctttc aatgctcgtt
    15361 tcaaattccc gcgaggatcg ccggcaaatg gtgtcccatc cggattatag atatcacaaa
    15421 ttaaacgagc aacttttcca tgagcacttt cccacgggaa gatcatccaa gtggagagat
    15481 ctggatacaa atacatatcg ctttcttcaa ttcgaacaaa tccttcaatc gaagaaccgt
    15541 caaacatcat tttattttct aatactttgt cgatctggct cactggaact tctacatttt
    15601 tgatcgtacc taagatgtct gtgaacatca atcgtaaaaa tcgtacgttt tcttcctcaa
    15661 tgattcgttt gatttcttca cctgttatct gtttctttac catggtatcc ctcttccttt
    15721 tttaatttat tcagtcaaag aattgtcttt gcaatccttg cgactgataa tgacctgttt
    15781 tgcttaaccc accttgcgcc aaaatctcat cacgaaaaat ttgtcgaacg tcatgatctg
    15841 tcaacggctt cttgtttttt gcttcttgtt ttttcgcctg tgccatttcg tatacacgtt
    15901 tgatcccagc catattcaat ccctctgaaa gatagtcttt aatctcaagc aacatatcaa
    15961 tatcattcag cgaatacata cgtcggtttc cttcgcttcg ttccggatga actaaatctt
    16021 gttcttcata atagcgaatt tgccgagcag acaaatcagt cagcttcata actgtaccaa
    16081 ttggaaatac ggacatagat cggcgcaatt ccttttctcc catcagacgt cccctttcgt
    16141 tttataagtt ggctaaagtg taccaattaa aaaaaatatt gtcaactgca tatgttaggt
    16201 tttctaacat gagatctcta ttttttataa aataacaaaa aaataagaac acaaaaaagg
    16261 tatctagttg attttcgtac cagatacctt ttatttttta ttatactgta ctatccttta
    16321 ttagtgtttt tatt
//
LOCUS       DACGMI010000064        15695 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.066, whole genome shotgun sequence.
ACCESSION   DACGMI010000064 DACGMI010000000
VERSION     DACGMI010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.066"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            234..1406
                     /locus_tag="IXT46_002350"
     CDS             234..1406
                     /locus_tag="IXT46_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015077585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HAQ4948247.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     gene            complement(1657..3654)
                     /gene="tkt"
                     /locus_tag="IXT46_002351"
     CDS             complement(1657..3654)
                     /gene="tkt"
                     /locus_tag="IXT46_002351"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAQ4948248.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPIGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(3756..4007)
                     /locus_tag="IXT46_002352"
     CDS             complement(3756..4007)
                     /locus_tag="IXT46_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAQ4948249.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            4154..4777
                     /gene="lexA"
                     /locus_tag="IXT46_002353"
     CDS             4154..4777
                     /gene="lexA"
                     /locus_tag="IXT46_002353"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAQ4948250.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            4956..5174
                     /locus_tag="IXT46_002354"
     CDS             4956..5174
                     /locus_tag="IXT46_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948251.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(5462..5974)
                     /locus_tag="IXT46_002355"
     CDS             complement(5462..5974)
                     /locus_tag="IXT46_002355"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAQ4948252.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(5988..8285)
                     /gene="recJ"
                     /locus_tag="IXT46_002356"
     CDS             complement(5988..8285)
                     /gene="recJ"
                     /locus_tag="IXT46_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAQ4948253.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLMHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPVE
                     FLDLVAIGTIADLVSLTDENRILVSLGINAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSN
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     IMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(8427..8861)
                     /locus_tag="IXT46_002357"
     CDS             complement(8427..8861)
                     /locus_tag="IXT46_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAQ4948254.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(8871..9659)
                     /locus_tag="IXT46_002358"
     CDS             complement(8871..9659)
                     /locus_tag="IXT46_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4948255.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(9656..10597)
                     /locus_tag="IXT46_002359"
     CDS             complement(9656..10597)
                     /locus_tag="IXT46_002359"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAQ4948256.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(10774..11361)
                     /locus_tag="IXT46_002360"
     CDS             complement(10774..11361)
                     /locus_tag="IXT46_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAQ4948257.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(11582..12895)
                     /gene="obgE"
                     /locus_tag="IXT46_002361"
     CDS             complement(11582..12895)
                     /gene="obgE"
                     /locus_tag="IXT46_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAQ4948258.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            13183..14193
                     /gene="gap"
                     /locus_tag="IXT46_002362"
     CDS             13183..14193
                     /gene="gap"
                     /locus_tag="IXT46_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAQ4948259.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(14278..15213)
                     /locus_tag="IXT46_002363"
     CDS             complement(14278..15213)
                     /locus_tag="IXT46_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4948260.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            15399..>15695
                     /locus_tag="IXT46_002364"
     CDS             15399..>15695
                     /locus_tag="IXT46_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4948261.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKER"
BASE COUNT         4508 a         3438 c         2767 g         4982 t
ORIGIN      
        1 gagcaatcgc ttttttattg atcaccattt ttcttttagg tctatggtgt cgggcactgc
       61 gggtcttcag ctcttgcatt caaattcctc ctcaaaataa aaaaacttaa taaaaagttc
      121 tcttcttaaa acgataaagt ccgtataatt gtgtaaaagt aaaaaggcca tataacagtc
      181 cttttacggt acaatgtttt taacgacaaa aacataccca ggaggacttt tacatgaccc
      241 aagtacattt tacactgaaa agcgaagaga ttcaaagcat tattgaatat tctgtaaagg
      301 atgacgtttc taaaaatatt ttaacaacgg tatttaatca actaatggaa aatcaacgaa
      361 cagaatatat tcaagcaaaa gaatatgaac gaacagaaaa ccgacaaagt caacgaaatg
      421 gctattatga gcgcagcttt acgacacgtg taggcacgct agaattaaaa gtacccagaa
      481 cacgtgatgg ccatttttca cccacagtgt ttgaacgtta tcaacgaaac gaaaaagccc
      541 tcatggcttc aatgttggaa atgtatgtat caggcgtttc aactcgtaaa gtatcaaaaa
      601 ttgtggaaga actttgtggt aaatccgtct ctaagtcctt cgtttctagc ttaacagaac
      661 agctagaacc tatggttaac gagtggcaga atcgtttatt atcagaaaaa aattatcctt
      721 acttaatgac cgatgtactc tatataaaag tacgagaaga aaatcgagta ctctcaaaaa
      781 gctgtcatat agcgattgga ataaccaaag atggcgaccg tgaaattatc ggcttcatga
      841 ttcaaagtgg cgaaagcgaa gagacctgga caacattttt tgaataccta aaagaacgcg
      901 gtttacaagg tacggaactc gttatttctg atgcgcacaa aggattagtc tctgccatta
      961 gaaaatcctt caccaacgta agttggcaaa gatgccaagt tcacttccta agaaatatct
     1021 ttaccaccat tcctaaaaaa aattcaaaat ctttcagaga agctgttaaa ggaattttta
     1081 agttcacaga tattaactta gcgcgtgagg ctaaaaatcg attgattcat gattatatcg
     1141 atcaaccaaa atattcaaaa gcttgcgcat cattggatga tggattcgaa gacgcctttc
     1201 aatataccgt acaaggaaat tcccacaatc gactaaagag taccaatcta attgaacgac
     1261 tgaatcaaga agtacgcaga agagaaaaga ttattcgcat cttccccaat caaacatcag
     1321 ccaatcgctt aattggagcc gttcttatgg acctacatga tgaatggatt tattcttcaa
     1381 gaaaatacat caattttgat aagtagaaat ggtaaaaaca ttgtatagca ttttacacag
     1441 gagtctggac ttgactctta aaacaaactt aattaattaa attatacttt taattctcaa
     1501 gaaacacaaa ctaatccgaa gaattctttg ttttgtcatt taaatgtaac atagccgaaa
     1561 acgaaaagta atattgattt attcttctaa cacataaaga acagctgtct ccaacttgca
     1621 gacagctgtt cttatcagtc aaacaattgc ttggatctat gatagttgat tgtacgtatt
     1681 cacgacattt tctactgtaa atccaaattc ttctaaaatt ttagtgccag gggcagatgc
     1741 accgaaatga tcgattgtaa tcgttgcgcc ctctgttcct acgtagcgtt cccaaccaaa
     1801 tgatgcagca gcttcgatag ccacacgttt cttcactgat ttaggaagta cactttcttt
     1861 atattcagaa gattgttttt caaagaggtc aaagcttggc atagaaacaa cagaaacatc
     1921 tttgcctttt tcagccaatt ctttttgagc tttcacagcc aaatcaactt cagaacctgt
     1981 tgcaatcaaa ataccttctg gtgtttctcc ttgtgatgga gaaagaacat acgcgccttt
     2041 tttcaccatt tcatctgcta cttcttttgt agaaggcaat actggaaggt tttgacgact
     2101 caatacaagg atagtaggcg catctgttgt ctccatcgct actttccaag cagcacgtgt
     2161 ttcatttccg tctgccggac gaatcacttg aacaccaggc atgcagcgaa cagatgctag
     2221 ttgttcaatc ggttcgtgcg ttggtccgtc ttctccgaca gcaaccgagt catgtgttaa
     2281 gacgtaaaca acaggagtat gttggattgc tgctaaacga actgctggtc ttagataatc
     2341 gacaaagaca aagaatgttc caccgtagat acgagttccg ccatgaagtt ggataccatt
     2401 catagccgaa gccattgcaa attcgcggac accgaaccag atgttgcgtc cttcataatg
     2461 ttcaggagtg aaatctttat ctgcagccac cattgtatta ttggaacctg acaagtccgc
     2521 tgaaccaccc cagaagcttg gtatagcttt cgataattct tggatgactt ctttacttga
     2581 aacacggctt gcttgactgc ttccaacttc ataagttggc aattctgcat cccagttttc
     2641 tggtagtttg ccatcaaaag catcttcaaa ttgttgtgct aattcaggat aagctttttt
     2701 ataattggca aacatttcat tccatgcatc ttcagctttt tgtccttctt ctatcatcgt
     2761 ttgatggaag cgggcagcta cttcttctgg aacagtgaaa tctggatact cccaaccata
     2821 aacttcttta gccatcttga tgccatcttc accaatagga gcaccatgaa cagcagatgt
     2881 tccttcttta ggagcaccat agccgatgac tgtttttact tcgatcaatg ttggtttgtc
     2941 tgtttcagct tttgcttctt caatcgcttt agagattgct tctaggtcat ttccgtcttt
     3001 cactaagata tgttgccagc catatgcttc atagcgagca ccaacgtttt ctgtgaaagc
     3061 ttttgaagtt ggaccgtcta gtgaaatatc gtttgaatcg tataaaacga tcaatttccc
     3121 tagtttcata tgacctgcca tcgaacttgc ttcttgagat accccttcca tcaagtctcc
     3181 gtcaccgcat attgcatacg tatagtgatc catcacatta aagttttctt tgttatacgt
     3241 tgctgcaagg tgcgcttctg ccattgccat accgacagcc attgcaatcc cttgtcctaa
     3301 tggccctgta gtggcttcta caccatctgt gtgatgtact tcaggatgtc ctggtgtttt
     3361 agaatcccat tgacggaatt gtttcaaatc atcgattgtc acttgatagc cagctaaatg
     3421 aagcaagcta tacaacattg ctgacccatg tcctgccgaa agaacgaaac ggtcgcggtc
     3481 agcccagttt tttgatgtcg ttggatttac tttcaggtgt tttgtccata acgcatatgc
     3541 cataggtgct gcgcccatcg gcaatccagg atgtcctgag tttgcttttt ggactgcttc
     3601 aatacttaat gtacgaattg tgttaacgcc aagttggtca attttgtcaa acaaaataac
     3661 ccctcctatt aatttaggtt ttttttacct ttatttctta cactttcatt ctataagatg
     3721 tcacacgaaa aagcaatctt tttcagtatt ttttactaaa agttgtcatt tcggttgtgt
     3781 aagccttttt tcttttggat ttcttttaat ttttccgggg tcacgtcatt gccctcagga
     3841 tcgacgactt tcattccttc gatatgatga cgcataccgg aacgaaaagc ttccaaatac
     3901 tctttgcgta agttgatttg ttcttgttct tcggcttttg agagaccatt ttccttcttt
     3961 ttacgtgcaa gttcattgat cctctctatt ttttcaggtg acagcatgct cagccctcct
     4021 tttactctcc ttcatattat ataaaaactg aaaaaaaaac aactagataa actaaataaa
     4081 atacgaacat tcgtttgatt tagcgctttt tatatggtac tatttattta tcaagtgaaa
     4141 gaaggtgtac cttgtggccc gacaaactga atcaagacaa atcgaagtct tacgatatat
     4201 ccatgaacaa gtaacccaaa aaggataccc gccgactgtc cgtgaaatcg gggaagctgt
     4261 tcagctttct tctacttcta ctgttcacgg tcatcttgca cggcttgaaa aaaaagggtt
     4321 tatccaaaga gatccgacga aacctcgtgc aatcgagttg acaaaacaag gtttagaaaa
     4381 gattgggatt cgtccaacaa ctattccagt acttggcgtc gtaacagctg gagaacccat
     4441 tttagcagta gaggatgctt cagacttctt tccaatccct cctaatcttt cttccgaaga
     4501 aggcagtctc tttatgctga caattcgtgg agatagtatg atcaatgctg ggatcttgga
     4561 tggtgacaac gtgatcgttc ggaagcaaga aactgctcaa aatggcgata ttgtcattgc
     4621 aatgactgcc gaggacgaag cgacttgcaa acgattctat aaagaaaaaa actttttccg
     4681 tctgcagcct gaaaacgact tgctcgaacc aatcatctta gatcaagtat ctatattagg
     4741 acgagtagta ggactttatc gtagtcatat ctattaattg ctactaataa aagaaaactt
     4801 tttaaaaaga gtttgagacg atggtctcaa actctttttt cgcccgggtt cttcttcttt
     4861 caaattttta tcacttccct ctttacaaac cgaacaaata ttcgtatact aaatatacga
     4921 acaattgttc gcataaatta acgaggtgag aattcatgaa atcaatgaga cgtcttggct
     4981 tagtattaac tgttttgttt ttaggtatta ttattggtaa tttcggcata cgtccagctt
     5041 tacttgtgtt tgttccgtta tttactttgt ggttcatgtt gtgggatgaa aagaagtacc
     5101 gtcaatctga gcggcgcaga attcatgaag atcatttcta tcatgagccc tactacagat
     5161 ccaggcaatc ataataagga ttgactgcta attattcaaa agacaagaag ttaaactttt
     5221 acgggggtgt gacaaaaatc ggtcacatcc ttttttcgaa taaacggtgt tctaaagcca
     5281 gtttttcggt attaagtcaa attgcggaaa aagtgatttt ttaaacttct actggtcttt
     5341 gcttgtttcc atttataaaa aaatagcgac cctcaaaagt cagatagaga atctgacttt
     5401 tgagggtcgc tttaaaatcg cttctttaag aataacatca agaatagctt cttttttctg
     5461 cttaatattc cattaatgta atgatgtcat atcctttgat tttgtcgcgt ccatggagat
     5521 ccatcaattc gatcaaaaat gcgcagccta cgactacacc gcctaattgt tcgatcagtt
     5581 cgatcgtcgc tttgattgtt cctccagtag ctagcaaatc gtcacaaatc agcacacgtt
     5641 gacctggttt aatggcatcc ttatgcaatg tcaatgtatc tgttccatat tctaatccat
     5701 aagtcacttc gatggtttct cgaggtaact tccctttttt gcggactggg gcaaaaccga
     5761 ctcctaactc ataagcaaca ggacatccta cgatgaatcc acgggcttct ggcccaacta
     5821 ccatatcaat tcgtttttct tttgcataat ttacgatttg cttcgtagct tcccgataag
     5881 cgtcaccatc tgccatcagt ggggaaatat ctcgaaacac aattcctttt gacggatagt
     5941 cgggaatact ggcaatataa tcttttaaat ccactctttg tttcctccta ggttgttaac
     6001 catttcttta tggtaggaat atcgctcaaa agcaaaaatt cctcaacttt gattttattg
     6061 agccgccgct ggtataatct gctctcagtc aaaggatgac tttctgggct agcgactttt
     6121 tgtaaaacac cgttctctat tgtaacaaat ttcaattcaa aaaacacctg tatcataaaa
     6181 attaataatt tttcagggat acgcaaatat tgagctattg cttttatttt atgacgtata
     6241 tcaattcgtt cttgagaatg gatcagttta aacaattttg cgtactgttc tcttgtgcct
     6301 accccattca aataggcctc atcaggcgaa atccccatca gataaacacg attgaatgaa
     6361 taagaccgaa aaacttcttt cagatccgct aaatcatctg gacaatccat aataactaga
     6421 gagttcggtt ttcttttttc aattattgcc tttacagaat ctagtccttc gaaaacaatc
     6481 gcagcttcct ggataatctc aggcacgaat ttcaacgtag aagaatcaaa tgctaaataa
     6541 aggctacctt ccgacgttcg gctctgttca cggaaacgtt ttgcccgcca atcaaatact
     6601 tgcagaccac ccacagaaaa atcagatacc atcagctgcg gtttcttacg cccgttccat
     6661 tcattgatcg aaagctttcc taccacatct acctgattat tcagcagttc ttcttcttga
     6721 gtaccaaaac caaaagcgac cgcatcaagc tgactcgatg cattggaaag gacaaatttc
     6781 agatgctgtt ggtttgctcc gattcttttg atattttctg cttggacttg tcgaaataaa
     6841 aactgaggca aaggattatc cgtaccaaat ggcgccaata gtttcagctc atcaattcgc
     6901 tctactgtta cttcatttgg cagcaatact tcatcaattc tcaactcagg ccctctcatc
     6961 aagtcaattt gatgatcgac tatatattgg ttcatcttct cctgtagtat agtgacattt
     7021 tcacttggca tcgttaaacc gactgctgca tgatgtcctc cgaagtaagt aaataaatct
     7081 cgcatctggt caagcatttc aaaaagattc aaggcttcaa tactacgtcc agatccttta
     7141 gctgatccat cttcttttaa agtaaggaca agcgttggtt tacccgtttc attcattatt
     7201 ttcccagcaa caatgcccaa aacgccttca tgccatcctc ggtttaccaa tagatggata
     7261 tgattctcct tattgaccat cgctaatgct tcttgtgtta tctgctctac gattgctttt
     7321 ctttcttcat tgatctcatt caattttttt gcttgaacgg atgcttcctc ttcatcaaac
     7381 gtcgcaagta acgagacggc aggacgtgga tcgcccatcc gaccgattgc atttagtctg
     7441 ggagcaatcg aaaaaccgat cgttgtttcg tctgcgtccc tcatttttac gccgctttct
     7501 tcaaatagcg cctgaagtcc tatccgttct gaatgatgaa tggcattgat tcctaatgaa
     7561 acaaggattc gattctcatc agtcaatgaa actaaatcgg cgatcgttcc tatcgctact
     7621 aaatccaaaa attctacagg cggttcttcc aataatgcag aagctacttt gaatgctact
     7681 ccgactcctg ccaaatctgg aaatggatag tgccccgctg gatgacgagg gtgaacaatc
     7741 gcataagcgt ctggtaaatt ctcaggtagt tcgtgatgat ctgtaatgat cacgtctaca
     7801 ccagcttgct gagcgtatgc taccgcatca tttcctgcta ccccgttatc aacagtgatg
     7861 atcaactgga ttccttcttc gatcttttct tggtatacag attggtttgg tccataccca
     7921 tgctcaaatc gatttggcag gaatacttct acttctgcac caagtaattc cagtgtttct
     7981 ttcattaccg ttgcactggt gatcccatct gcgtcataat caccgtaaac gaggattttt
     8041 tctccactga ttacagcttc ttggattcgg ctgattgctt tatccatatc gtgcatcaga
     8101 tacggatcat gtaattcttg ttcctttgga tgtaaaaatc ggttgatatc cttttcctca
     8161 tggtaacctc tttgccacag taacttaccg acaaatggag ataatttcag ttcacggatc
     8221 atttggagaa aggattcaga aggctctgtc tcgcttaact tccaatcaaa atttgcttgt
     8281 ctcactttct cactcctaac ttagttatta tagcaaagga aatcagcaaa aaaaagcaga
     8341 aagaaagaat aaaaacagat cagatccgct agacagatgt tcagcaggac ctgatctttt
     8401 gtacgaccat ttatgaaata tccctattag tcaaaataat tgaagctttg tttgggcgat
     8461 tgagtttttt gttcttccgg cgctttcaat tgactgattt gtgcggtttt cgcttgtaac
     8521 tccgcctgat aagcagcttc caactccgca cgttcgtttc taaactcgcg ttgctgttct
     8581 tcttttgctt cttcaatttt cttttgaagt tctgtttgat attctgacat ttcctgagtc
     8641 agctgtttga tttgcttttt ttgctgccat agtgttgccg aagcagtcaa aaatacaatc
     8701 agtgcaccaa tcagcgcaga accgatgatc actaagatca atggcgcaga aaaggaagtg
     8761 aagccaaaac ttacaggaac atttttattg ttcaatacag caaaaagaac aataatcaaa
     8821 actaaaacaa atccaagaat cacattgctt tgctttttca attccttcac ctactttttg
     8881 ttaaaaattc cgctggctaa ataatcacca atcgttggaa acagcgtata aaattttgat
     8941 gcaacttcta aaataaacgg ttgattgatt tcccgttttg gatgtctcat attgcggacg
     9001 atcatttttg ccaacttggc aggttctaaa acgatttgtc cgactttttc caaatagctt
     9061 ccgcttggat cagccttatc gaagaaatct gtctcgattg gacctggatt cactgtcgta
     9121 acagctacgc caagtggttt caattctaat cgcaaagcgt tggagaagcc aaggactgca
     9181 aatttcgtgg cagaataaac cgttgatttt gcagttgcca tttttccagc catagacgcg
     9241 atattaatga tatgaccttg tcttctttct gccatatcga tcgcaaattt ttgtgtcaaa
     9301 accatcattc ctaagatgtt gacttcaaac atatcgtatg cttttccaag gtcgaatgta
     9361 aggaagtctt cgaaaatccc aaaacccgca ttgtttacca gaatatcgac gcgcccgact
     9421 tcttccatca ccttttcata taattcgtcc acgctttcag gattgctgac gtctaccttg
     9481 aaagcataag cctctttgcc gctcaagcgt ctgcactcgt ctctgacacc ttctacaaat
     9541 gccattcttc gtgcgcaact tataacgatt gctccttgct ttgctgcttc ataacagatt
     9601 tgtgcgccca gaccgcctga actacctgtt actaaaacaa ctttatcttc taaattcatg
     9661 cctcttcctc ctcgcgaaat ggaatctcaa tgctatcaaa atctttcatg atcgtcgtgt
     9721 tttcaaacac ttcttgtgct tctttttcaa gctctaaagc tgcttttcct aaatatctcg
     9781 cactgatatg agtaagtagc agccgttttg cctgcgcttc ttttgcaact tcagcagctt
     9841 gatgagtcgt ggaatggaaa tagttgtgcg ccattcttgc ttcatcttta ttaaatgtgc
     9901 tttcatgtac cagaatatcg ctattttccg caagcacaac ggaattatgt gtttttctcg
     9961 tatcgcctaa aatagtcacg attcgtcctt ttttatctgg acctacgaaa tcttttccat
    10021 tgatcgtccg cccatcttct agttggatcg tttcaccttg cttcagtttg ccgtacagtg
    10081 gtccagctgg aatacctaat tcttttagac gatccacctg caattctcct ttatgatcat
    10141 gttcaaccac acgataacca aaactgtcga tcccatgatt tagttttttt gtataaacag
    10201 aaaattgctg atcagtaaaa atcggggctg tttcatttag ctcaatgaat ttcagcggat
    10261 aacttaaacg cgtttgcgaa atacctaaag agacttttat gtattcctct atcccttttg
    10321 gcccgtaaat ctctaatggc gtatccccac cttgaaatga ccggctgctg atgagcccgg
    10381 gaagtccaaa aatatgatcg ccgtgtaaat gtgtaataaa aattttaccg atttttctcg
    10441 gacgaatagt cgttcgcaaa atctgcattt gcgtgccttc gccacagtcg aacaaccaaa
    10501 cttcattgcg ctcgtctaaa agtttcaatg ctatacttgt cacatttcta tgttttgcag
    10561 gaacacctgc acctgttcct aaaaattgta attccataat ctacctgact ttctttaagt
    10621 tcctctttaa ttttagggta aaaagaaggg ataatcaacc gtaagtcgag aatgggttca
    10681 aattaaaaat aacgttctaa agcgatagcg ttttctttga aaattactat aaaaacagca
    10741 gcgaacccgt ttgagatcct ctgctgtttt ttattaattt gaagatccag aactttcatt
    10801 gtcgttggaa gtttgcggat gtttgtcctt ccaagtcttt tgtgcagctt ctttcgcatg
    10861 attttcagct tctttcgcat catgcacatc tttttcgaca tcttcataat ccaagcgggt
    10921 aatttctccg cctaattcca tcattaccaa ttgattcagt gggcgattgt cctcttcatc
    10981 agcaatcaag atcagtcctg tagctccttc accgatttta tttcctacaa agtcgaacac
    11041 ggtctgggca tcttttattt ctttggcatc ttgtgtcgca ccgatcattc ctccggcaaa
    11101 ccatcctaat aaaatcccta gcggaccacc taatacacca accaacattc cgattaatcc
    11161 acccgtagaa gatttgttat taccggtaaa gtcgataaaa tcttctattt tgaattgatg
    11221 tgtcccatta ggatcatggc tgacaactgc catctgttct cctttaatcg aacgaacagc
    11281 atgtaacttt ttgatttctg aaaatgcctg atatgcctgg ctttctactt gaaaatttaa
    11341 aatgattact cgtttgctca ttaaaaacgc ccctttcata ccttcttgtt atttatttta
    11401 cctttaattg taaaataaga aaagaaaagc actctttttt tccaataaaa tagggctgtg
    11461 acaaaagtcg tatcacagct cctttttccg aataaacggc gttcttgaag ctgatcactt
    11521 ctgtcacaac ctcccttaaa tctgaatcta tattttttgg tatttgtttt tatttgcttg
    11581 cctattcgac aaattcaaat tcaaactcac cgatacgtac aaggtcgcca tctttcgcac
    11641 cgcgtgcccg aagagcttca tccacaccca taccacgtaa ttgacgagca aaacgcatca
    11701 ctgtttcatc atgatcgaaa ttcgtcattt ggaataattt ttcgatcttc tcaccagata
    11761 agatccacgt tgcatctgaa tcacgatcga tttggaactc aggaccttct ggattgaatc
    11821 catagtgtac agtttcttct tccagttctt cttcgtacaa tgggaattct ggcgttactt
    11881 ctaacaaatc tgctgtagca ttcaataacg cgtccaatcc ttgtcgagtc actccagaaa
    11941 ttggaaatac tgggatgtca tcagcaaatt catcttcttt ttccttgttc agctgttctt
    12001 tgaatttcac tagattttcc ggtgcatccg gcatatccat tttgtttgcc acgatgattt
    12061 gcggacgctc tagcaagcgt aagttataag tagataattc tttgttgatg gcaagatagt
    12121 cttcataagg atctcgtcct tccatcccac tcatatcgat cacatgtaaa attactcgtg
    12181 ttctttcgat atgacgaagg aattgtgtac ccagcccaac accttgcgaa gctccttcaa
    12241 tcaagcctgg caagtctgct gcggcaaaac ttctgccatc acttgtagta accattccta
    12301 gattagggac gagcgtcgtg aaatgataag cgccgatttt tggacgagca gatgaaataa
    12361 cggatagtaa agtcgatttc ccgacagatg gaaaacctac aagtccaacg tctgccaata
    12421 ctttcaattc tagttcgatt tttcgctctt gtcctggttc gccgttttca gcaatttccg
    12481 gtgcaggatt ccgaggagag gcaaaacgga tattccctcg tccaccgcgt ccaccttttg
    12541 ccacaactag tgtttgacca ttttcaatta aatctcctaa aagagcacca gtctccgcat
    12601 ctcggacagt ggttccttgt ggtactttaa cataggtatc ttctgaacca cgaccgtgca
    12661 tccctttact catcccattt tcacctggct gcgctttgaa atggcgattg aaccgaaaat
    12721 ccatcaatgt acgtaaccct tcatcgacga tcaagatgac atcgccgcca cgaccaccgt
    12781 ctccgccagc cggtccgccg tcaggaacgt atttttcgcg acgaaatgca accattccgt
    12841 ctccgccctt gccagctttc acatcgatcg ttacttgatc taaaaacatg gacataatta
    12901 agtcctccta ttattcattt atttatttga ctgcctgaat ttccacaata aacaaaagtc
    12961 ttacttattt tatcggtgaa atctgatttt gtctatcatt tcagcaaaaa gattgtttac
    13021 cttcttcttt ttttatcatt tggtaaggtt tccaaccttt tttctgctac caagtataat
    13081 tttttgacaa aatattcttt gcgtagcaga ataacagtgt attaattgta ttaattgagg
    13141 atgccgtttc acagcacccc taataaagga ggaacttttg atatgacagt aaaagtaggt
    13201 attaacggat ttgggcgtat tggccgtctg gctttccgcc gcatcaaaga agtctcagat
    13261 gatattgaag tagtagcaat caacgactta acaagtccaa ctatgttagc acaattattg
    13321 caatttgact ctactcatgg tacttatcct ggcacagtta ctgcaacaga agactcaatc
    13381 gtagtggatg gcgaagcaac tcgtgtttat gcagaacccg acgcaagcaa aatcccttgg
    13441 gcaaaagaaa acggtgtaga tatcgtacta gaatgtactg gtttttatac atctgaagaa
    13501 aaagcaaaag cgcatttaga tgctggtgtc aaacgagtag ttatttctgc cccagctggt
    13561 gctatgaaaa ccatcgtcta taacgtcaat gatgatacat tagatgaaaa cgacaaaatc
    13621 atctcagcag gttcatgtac aacaaactgt ttagcaccta tggcttattt cttaaataat
    13681 gaatttggga tcgaagttgg tacaatgaca acagttcatg cctacacttc cacacaaatg
    13741 ctcttagatg gacctgtaaa aggcggtaat ttgcgtgctg ctcgttcagc tgctgacaat
    13801 actatcccac attctactgg tgctgcgaaa gcaatcggct tagttatccc tgagctacaa
    13861 ggaaaattac aaggacacgc acaacgtgtt ccagtcgttg atggttcatt aactgaattg
    13921 gtttcagtat tgaaaacaaa agtaactgct gatcaagtaa acgaagcaat caaaaaacac
    13981 acagttgaca atccttcatt cgggtatgat gaccgtcaaa tcgtttctag cgatgtcatt
    14041 ggaacaactc aaggttcgat ctttgaccca acgcaaacag aagtaacaac tgctggtgat
    14101 ttccaacttg ttaaaactgt tgcatggtat gacaatgagt atggatttac ttgccaaatg
    14161 attcgcttac tagaaaaatt cgctaacttg taatttgata gatcaatcga taaaagaagc
    14221 ctttgactgg atccagtcaa aggcttcttt cttttcatcc cctactttta aactcgttca
    14281 atgaacatat tggcttaaaa attgttggac tacttgctga tatttttcag gatctgtctt
    14341 gtatgcttcc gcatgctcgg ctccttttac aacatacttt tcttttggtc ccttcgttgc
    14401 acgatagacc ttatctaaca tttcaaatgg tacaaatgta tcttcgtctc catgtataaa
    14461 gagcattggg cgctggtttt tcttcaattg ttccactgca tttgcttcac cgaaaaagta
    14521 gccagcacgg acttttgtca ctagactcgt tacttgcata agcggaaatg ctggaagact
    14581 aaacatatcg tctagctgat aagcaagctc atcatgaacg gaagaataac cgcaatcttc
    14641 aatgattgct ttcacattat ctggtagttt ttctccgcta gtcatcataa ctgttgctgc
    14701 tcccatgctg acaccgtata gaacgatttc ttgcgatttt ccattgtttt ctagcacttt
    14761 gtttatccac tgtacatagt ctttacgctc tggccatcca aatccaatgt aatccccttc
    14821 gctttttcca tgtcctcttg catcaggaac aaggacattg taacccatat catgaaacat
    14881 ctttgcgtaa ttggtcatcg tttcagcgtt tcccatatag ccatgagcca caagagctgt
    14941 tttttcactt ttcgtttcag caggaagata aatcgctgat aatttcagac cgtcttttga
    15001 agtgatggtc caatcgcttc ggttttcttt tgaactaaac catttatgtg catccgtttc
    15061 tttggatgtc tgtgttgtac caggtgtatc ttcgtctaaa aagtctttct cagaaggcac
    15121 aacagcataa ttataaaaat aattccctgc aaacactaac gcaacaatca gagctaaagc
    15181 gacgcctaaa aggattttca tccaaagttt cataaatcat ccatctcatt tctctttttt
    15241 catataacct tgaattagta taatcaaaga atctctacta tgcaatgttc atttttataa
    15301 cccgcgaatt gtaaaattaa gttagaaaaa taaaaaggca tttatggtac actcaaattg
    15361 tatttccgac gaaagaaaac aaaggagtgt aaccataaat gacctacaaa catcttacca
    15421 tagacgaact gacaatgata gaatcatatt atcttcaaca taataagccg gttgaaatcg
    15481 ctaaccgaat gggacgtgct atacaaacta tttataatgt agtcaataag ttcaagcaag
    15541 gcaagactgc tcttgattat tggcaccagt ataaagaaaa taagaaaaaa tgtggtagaa
    15601 aagtcattca attacctgct catgaagtag attacattaa agagaaagtc actcttggtt
    15661 ggacgcctga cgtcattatc gggcgaaaag aaagg
//
LOCUS       DACGMI010000065        15687 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.067, whole genome shotgun sequence.
ACCESSION   DACGMI010000065 DACGMI010000000
VERSION     DACGMI010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.067"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..781
                     /locus_tag="IXT46_002365"
     CDS             <1..781
                     /locus_tag="IXT46_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAQ4948262.1"
                     /translation="KSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRK
                     ARLKVKYLVMDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTS
                     HSENQKKYRRLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRT
                     AYHFCQLLRYYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHS
                     NGVTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            complement(1164..1892)
                     /locus_tag="IXT46_002366"
     CDS             complement(1164..1892)
                     /locus_tag="IXT46_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4948263.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1870..3444)
                     /locus_tag="IXT46_002367"
     CDS             complement(1870..3444)
                     /locus_tag="IXT46_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4948264.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            3673..4611
                     /locus_tag="IXT46_002368"
     CDS             3673..4611
                     /locus_tag="IXT46_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4948265.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            4623..5534
                     /locus_tag="IXT46_002369"
     CDS             4623..5534
                     /locus_tag="IXT46_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4948266.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            5558..7030
                     /locus_tag="IXT46_002370"
     CDS             5558..7030
                     /locus_tag="IXT46_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4948267.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            7081..7692
                     /locus_tag="IXT46_002371"
     CDS             7081..7692
                     /locus_tag="IXT46_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAQ4948268.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            7722..9635
                     /locus_tag="IXT46_002372"
     CDS             7722..9635
                     /locus_tag="IXT46_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HAQ4948269.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            9763..12744
                     /locus_tag="IXT46_002373"
     CDS             9763..12744
                     /locus_tag="IXT46_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HAQ4948270.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            12741..14402
                     /locus_tag="IXT46_002374"
     CDS             12741..14402
                     /locus_tag="IXT46_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HAQ4948271.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SAKLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            14442..15374
                     /locus_tag="IXT46_002375"
     CDS             14442..15374
                     /locus_tag="IXT46_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAQ4948272.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         5088 a         2523 c         3137 g         4939 t
ORIGIN      
        1 caaatcaatg aattctgttt ctggttccat gagttttatt tgtgttgatg ggacaaccaa
       61 tcagctattt acgatccttg aagatcgcag actttacaaa ctaactcaat acttcctgcg
      121 ctttcctaga aaggcccgtt taaaggtcaa gtacctagtg atggacatga atgccagcta
      181 ttgtcagttg cttaaaacag tctttccaaa tgcggagatc gtaactgacc gctttcatat
      241 tgtccaacac atcaatcgca gcttcaatca attacgtgtc cagatcatga atcgttttcg
      301 aacctcacac tctgaaaatc agaagaagta ccgtcggctc aagcgatatt ggaaactctt
      361 actcaaagat tccacgacat gggagccact caaacggcat tatcatcgac tgtttaaacg
      421 accaattagt caaacagaaa tcgttgatga gctgttaagc tacaacgaag aattgcgaac
      481 tgcgtatcat ttttgtcaat tattacgcta ttatttcgtt aaacgaggta cggaaggctt
      541 tcaagaaacc cttaaaacaa tttcatctac gttacctcag tcgtttaaaa agaaattcac
      601 gatcttccat tgctaccaat cgggtatttc aaatgccttt aaggtgtccc actcaaacgg
      661 cgtcactgag gggctgaata acaagatcaa gctgattaaa cgaattgcgt ttggttatcg
      721 caacttttat aactttcggg cacggatcta tttacaacaa ggtctgatct ttgaaaacta
      781 aaaaaatatg cggcgcacag aacgcgccgc atatcggact aagttttatt caaatttgtc
      841 ttcaccaaca cgatttgacg aagagcctat ttaaataact acatccattt attctatctt
      901 ctaaaatagc ctttttcatt tcagttaaat agttcagcgc catttttgca ctcgacttgc
      961 atagtagttt tttccatatt cctcaacctc agcgggggtt gaagacataa ggaaaatcct
     1021 atgcgttatg ctcaactgga tctgattaaa tattctaatg tatttttctc taccatcatt
     1081 aaatggttaa tagccaaaaa tcaccacttt tcaatggctc cttgttgtat aagtataact
     1141 agaagatgaa cacgtctgag aaattataga agctttttac ggtaattact ggggctgtgt
     1201 ccagtagttt ttttgaagag aacagaaaaa tagctcacgt gatctattcc tactttttga
     1261 ctaatttcat caatagataa gaatgtgtct ttcagtagag cacttgctct tttgattcga
     1321 aagtctagca agtaatcatg aaaggaataa cctgtttctt ttttgaaggc ccgtcctaaa
     1381 taagcgggat ggtaatggaa ttgtgtagct acatctttga gcgtaagctt ttcactataa
     1441 ttgttttgaa cgtaatcaat cacttgttga attgactcat taaaagaatc atcagttaga
     1501 gagttttgat tagctgctga tttacgcatt ttttcttctt gtactaactt aactaaataa
     1561 ggaaaatcaa tgggtttcgt tatgtaactt ttaatagata aatcaatccc cttttttgca
     1621 tactgaaaat tttggtgggc actaatgaca atactagtaa agtagcgatt ggatgtttgt
     1681 tgcaaagatt cgattaattc gagtccagaa attttcccca tcgtaatatc tgtgataagt
     1741 aaatcaaagc gctggttttg caggttttta aatgcttcgt ctccgtctgt gtagcagtga
     1801 tcgataatga tgtcggggac tttcttcaaa agataatgcc ttatgccttc tacaattgta
     1861 caatcatcgt caacaattgc aattctcaac atgcatattc cccccttttt gtattttgat
     1921 agtaatcgtt gttccgacgt gtagttggct ttctataaca aaacgtgtat ctccaggata
     1981 gagatgcttt atacgtcgaa aagaatttga gatgccgata ttctcactat aaggaatatc
     2041 atcattaagt ttttgttgaa tatgctccag cttgtcttgg tccattcctt tcccattttc
     2101 aacgattttt aacacataat ggttggttgt ttcagttgca tagacagtca aacgattttc
     2161 cttttttgat gaatcgaagc cgtgtttaat ataattttca acaaatggct gtaaagaaag
     2221 ttttggtaac attaattgat caatatgatc aatcagctga tagtcaaagt tatgtcgata
     2281 acgacgttga tgtagttgca aggagaggtc gatattaatt aattcctctt tcaaatcaat
     2341 tatgtcgggc tgatatgtat tattgcgata caacttgctc aataaatata tactgtcgct
     2401 gatttcttcg tcatcattca atatggcagt cattcgaata aattccaaat tattaaatag
     2461 aaaatgaggc tcgatttgat attgaagtgc tgcatacttt gcttcttgct tcaaccaatt
     2521 attttcataa agtgtttttt gatatgtagc attatctaaa taaaactgat tgatatgcat
     2581 agcgatttct ttcaaatcac cgactttgtt ttcgatattg attgacttgt agtctcctgt
     2641 agatgaatga tttaaggaag taatgatttc ctgatactgc tggatatagt tacgaaaact
     2701 tctatttaat aattgatgaa tagcaagaat aaacaaactc attaataaga aaatcatgat
     2761 tgccagacct aataaggttt gtgacgaata atttggattt tcatatactt gtaatgtgtg
     2821 gttaccgata gctatctgtt gcgttttttt ccatttagaa ggcgagatgt cttcagataa
     2881 attgacggaa tcaataccat tagacaaaga ataattgtaa tgtgttggaa agagactctt
     2941 ttttagcgcg ttgatcgaaa cgtctagaat caatgtagca tcgggcatgt cctcactaat
     3001 gaaacttaat gaacgaataa aagaaatttt ttcgtttttt gtaggtgcgt aggcacttaa
     3061 gtatttttcg taatctaatg agatagatat atttttaact tcatcatctt gcacaagttt
     3121 ttttaagtta tctactaaat aggtagggga gcgatccttt gacaaaatat cttccatgta
     3181 ttcagcaggt gatgagaggt agtagtcatt aaggttttct tggaaatcat aattttgata
     3241 gatctctgtc acgataccgg agagaatacg attatatgtt tccatatagt gggtgatttg
     3301 ctgaatgttt tgcaggtttt gatttttttc tttttcaatc acattgatat aggaaaagaa
     3361 caatgtgaaa caggcaagta aagtaataaa aaaaatcaat atgtatgtaa aacgcataat
     3421 aacttttgat aaatcgtttt tcattcaaag tcctcatttt gataatctct aattttatga
     3481 atcattatag cacatattac aagtgatgta aacgctttgc aaacagggct acttatgatt
     3541 gtgaatacag tttccgttta aaaactattc tattgtagag gtttaataaa ctaaaaataa
     3601 tgtataaaaa attaatgtaa gcgattaacc aagtgggtat aatcaaggaa acgctgagag
     3661 aggagagaca aaatgaagct aaagaaaggg ttattaggaa atctaaaaaa aaaccgagca
     3721 ttgtttatta tgcttttacc aggtgcgtta tggttattta tattttgcta tataccaatg
     3781 tttggagttg taatcgcttt taaagatttc agaatttcat caaggggatt ctttacaagt
     3841 ttgttcaaca gtccttgggt tggctgggaa aatttcaaat atctctttgc ttcgcaagat
     3901 gcttggatca ttactcgcaa tacggttgtt tataacgttg taggtatttt gctaagtact
     3961 ttttgtacag tgtcattagc aatcattctg agccaaatgg cgaacaaacg gttattgaaa
     4021 aagatgcaga catttatgat ttttcctaat tttttatcat gggtagtcat cagttacttt
     4081 gtttacgcat ttttgagtac ggataaagga ttaattaata ttttactaag caattttggt
     4141 gtggaaccca taaattggta tagtgaaccg aagtactggc cttttattat tgtttttacg
     4201 agtttatgga aaggcgtagg ctatggatcc atcatttatt acgcgtcaat tatggggatc
     4261 gatactagtt attatgaagc tgctttagtt gatggtgcca gtaaatggca acagataagg
     4321 aatgtagtct tgccacattt aagatcgatt attgtcatta tgttgatttt gtctgttggt
     4381 agtatttttc gagctgattt tggattgttt tatcaattgc caagaaattc gggggctctt
     4441 tatgatgtga cgaatgtatt agatacttat gtctaccgtg gattaatgaa tagcggagat
     4501 atcggaatgt ctacggcagc gggattatat cagtcatcag ttggctttgt cttgattttg
     4561 attactaata agatagtcaa caagttagat cctagttcag cactatttta ggaggaatca
     4621 aaatgatatc aaaattaaaa cggcagatgt acttttcgct gccagtcgaa cggtttttca
     4681 caatattact aatcttattt actcttagct gtatttttcc ctttattttc gtaatcgtca
     4741 tttcattaac agatgaaaaa gcattacaac tcaacggtta cgaattattg ccggctcaat
     4801 ggagcactga tgcatatcaa tacttaatac aagatggcgg acagttactt cggtcattag
     4861 gcgttacaat tatgattaca gtgattggaa cgttgattac tgtttttatg acgggaacct
     4921 atgcttatgt tttatcaaga gcctctttcc cttaccggaa gttctttact ttttatcttt
     4981 tttttaccat gttatttgcg ggagggatgg ttccttctta cttagtgatg acgaagatgc
     5041 ttggcttaaa aaatacaatt tgggctttga ttctacctct tgcttttagc ccatacaatg
     5101 tcattatttt aaggacattc tttaagaagt cgattccaga atcgattatc gaatccgcta
     5161 aaatggatgg ctgtagtgag tttcgagttt ttttccaaat cgttttgcct ttagcgatcc
     5221 caggggttgc aacaataggt ttattttcaa gcttaggtta ttggaatgac tggttcaacg
     5281 cattgctgta tattgacacc aacaaattga ttccattgca atatttgtta atgaagattc
     5341 aaaattcaat ggaattctta gcaaataata atgacattac attagcgcag caacaagcaa
     5401 ttcaaaatag ccttcctcaa gaatcaacac gaatggcaat ggtcgtagta gctactttac
     5461 cgattgcaat tgtttatccg ttcttccaaa aatactttgt tcaaggattg acgatcggtg
     5521 gagtgaaaga ataaaaaaga ataggagatg ttaaaagatg aaaaagaaca tgcagaaata
     5581 tttgattggt ggtgcttctg tactaaccct tggcctatta ggtgcttgtg gtagcagtaa
     5641 tggcgaagca aataatgaaa caggaaccac aaaagttact tggtatcagg ttggagaaga
     5701 acccaaagat tttgatgagg tcatgacaaa agtcaacgaa aaattaaagg aagaaatcaa
     5761 tgtagagttg gatatgcggc tgattccgga cggggattat cagcaaaagc ttggtgtgat
     5821 gatcaattca ggagaagaat atgatatttg tttcgtcaat ggcacagatt atgtgaatta
     5881 tgggaacaaa ggtgctttca ttagtctcaa cgatcatttg gataaagagt tgaaagatta
     5941 tgcagctgaa ttgaatgaag gatttattga aggtggggca attaatggcg aaacttatgg
     6001 attgccagtc aataacgata ttgccacaac ggaatattgg acctttaata aagatttggt
     6061 agatcaatac caattggatg tagagaatgt tgaaggtgta gaaacattgg ctccagtatt
     6121 agaaaagttt gcagaaaaaa atactgatac gaatattacg ccaatcggta tgacccgtac
     6181 cagtgtctgt attccttatg acaatattat cggtggtggt gtaccgctag cggttgcatt
     6241 tgaaggcgat acacaaacag ttgttaatac ttatgagact ccagaaatga tgacttattt
     6301 gaaggctatg catgagtttt ataaaaaagg atatattttg aaagatgcag ccactgttac
     6361 gacagatcca tttcgaattg atagtaaaaa ctggttttta ggtcgtaact caagtggtta
     6421 tcaaccatta gcacaaaaaa aattagaagc tctagcggga catggattaa ttttaaaacc
     6481 agctggaaaa gcttttaaaa cgactggatt tgcaagagtg gcaatgcatg cggtatctgc
     6541 ttcaagtaaa catccggaag cagccttgaa attgttgaat tatgtgaata ccaatcaaga
     6601 agtagcggat ttaatggttt atggaattga aggaaaacac tatgatcgca atgaagatgg
     6661 ttcgattact ttaacaaact ctgatgatta ttatcaaggc gcttgggcat tggtaaatac
     6721 ttatctagtt tcaaaaactt caccgattac agaagaaagt aaaaaactag aagaagaaag
     6781 taaaaagttt caaaatgaag caccgatgtc tcctatttta ggtttctctt ttgacgcttc
     6841 tgattttcga acagaaattg caagtgtaca aaatatcgtg tcacaatatg aagtactttt
     6901 aagctcggga acagttgacc ctgaacaata tgtaccagag ttgttagaaa aactagaaaa
     6961 agctggattg gataaaattc aggcatctgc tcaagaacaa tacgatgaat ggcgaaaatc
     7021 taacaaataa ttttttacta aatgaaaaga atagactaag cagttagtgg ggggattcaa
     7081 atgaacgaaa acaaatggac caaaggattt aattgggttt ttcaattgtt gttactaaac
     7141 tttacttatt ttatactaat ttgtttagga tttggaattt taggtttttt ccctgctacg
     7201 atagctttga ttgctggcgt tgtgaatcga aaaaaatatg gcttgcaaga gtctgtgaag
     7261 ttcatgagta aaatctataa gaaaaatttt gttagatata atctatattg ctggtcagca
     7321 actttgttgt tggccggcaa tattactacg atctggcttt gttggcagca aagcgcacca
     7381 ttgttttatt tattaagtac attattatcg gtaattacac tgttcctagt ctttgcaatg
     7441 ttgaattggg tcgtgatcaa aagtcttggg ttgtggatga tgggagaccg actgattgac
     7501 tatttgcttt tcacagcaac gatgttgcca acggtagtca tgcaaggctt ggtgcttgga
     7561 atttatttcc gaatattgat gattttgcct gtgatttttc tgtttggcgg aacagctgta
     7621 acggtaatat tgattagtaa attaactgaa agagcgttag caaagttgcc ttgtcagata
     7681 caatcgcact aattttttca caaaaaggag tatttctttc tatgaagtta actgataaac
     7741 aagtagctaa tatagccttt atccagcaac ttgagattcc attgacacaa aaagatgaag
     7801 aacaaataga cttgattttt actgacacaa aggctaatgt gcgacaaatc aagattacta
     7861 aaaatgagca gcaacgaatt tgcttgtctt attcacatga agacttgctg tatcgaggat
     7921 tgtttatctg ccttccacgt tttttagctc aaggaggaga gatgccatac attgaagaaa
     7981 cctcgatcat tgagaccagt tattcattag atgcttctcg taatggcgtg atgaataaag
     8041 agactctaaa aaaattcatt tcttacttag cgttgatggg gtacaacaca ttgtatattt
     8101 acacagaaga tacctatgaa gtagaagacc ttccatattt tggttacctt cgcggagcgt
     8161 atacaaaaga agaagtgaat gaaattgttg aatttgcttc tggttttggc atagaagtag
     8221 ttccatcgat ccagaccctt gctcacttga cccaattttt gaagtggtat gctcaacaag
     8281 aactgatgga tgatcaaaat actctactga tcggtgaaga aaaggtttat gcggcaatcg
     8341 aaaagatgat tattgcctgc aaagaaatgt atcagacaga gcgtattcat ttgggaatgg
     8401 atgaagccta tcaagcaggt ctgggacgat atttaagcct gtatgggtat tgtgatcgga
     8461 caactttaat gattcaacat atggaccgtg tgttatcaat tgttgataaa tataagatga
     8521 aaccaatgat ttggagtgat ttcatttata agctattaga tgaaaccggt aaagataggt
     8581 attacaatcc tgattttaaa ctcaaagcat tagcagctaa aggattacca gcaggattaa
     8641 cctatgttca ttgggactat ggttcagatg aagtttcctc ctatgagaaa gtaattgata
     8701 accatttgaa attttgtgac attgatcatt acgttttagc tagtggtgcc catatctggg
     8761 ggagactagc cccgaatcat gggaaaacag aagcaattgt ttctgcagct gtaaaagctt
     8821 ctaaaaataa aggtgtacgt tctgtgatgt taactacttg gggagatgaa gggcaggaaa
     8881 cagagcattg gcattcctta attggggcat taaaattagc agattatgtc tattctgaag
     8941 aagagtggaa tgattttgag gaaatctacg atcgtttatt aggaacaggt agttatcaat
     9001 taatgtccga attacgatat ttcgatgaag tggataccat tacaaataac aacttacaaa
     9061 tggcttccgt gagtaaactg ctactttggc aagatccgtt agttggtata tatgactttc
     9121 atgtagccgc tcataacaaa attgccacta gaacaattgg tacttattat catgagttag
     9181 ctcagaaatt agatatgaat aaaaattgga atccaaaaca accaatttta acaactattc
     9241 gtcaacgata tatactttta gctgaaattt tagcacaaaa ggcagaacta ggcatctatt
     9301 tacaacactg ctgtctggta gaagaccttg caggattaat ggaattagcg aatcggtgtg
     9361 aagcactagc caatcgagta aatgaattgg catctattca tgaaataatt tggtatcaaa
     9421 catacaaaac ctatggttgg gaagtattag aacaacgata tgctgcatta gctcatcgtc
     9481 tgaaaaccgt tgcgcgtcgt attaaaaatc atcttcaggg gcaagatgcc ctagaggagc
     9541 ttttggaaga acgattaccg ttttgtcaat atcaagtgcc gcttgaaatt tctggcttta
     9601 attatcggca aagctcggtg tcaggctaca attaacgaag gaatcttccc gttgaacgga
     9661 ccacttgctc atctaatggg aaagtggttc gttttctatt cataagtagc ttaccactaa
     9721 ctcttttatt aagaagagaa aaaaagtagg aagtgagaaa atatgttatc ggactattat
     9781 caaaatctgt cagttataag tgtcaataca gaaccattac gtaattatta tattccttat
     9841 gcaagtaaag aagaagcaaa acaagagtta gaaagggaaa aaacgagcca gtttatcgat
     9901 ctcaatggta catgggattt tcagtattat ccttctgtcc aacagttacc ggaaaatttt
     9961 tttcaagagg cctttactga aagctatgat agaatttctg ttcctggagt ttggcaaaca
    10021 gagggatttg acttacctca gtatatcaat gtatcttatc caattccttt tgatccgcct
    10081 tatgtaccta atgatacccc ttgtggtgta tatcggcgtc agtttcaaat tgagcaaaca
    10141 gatgcacgct tttacttaaa tctagaagga gcagatagta attgttttgt ttggataaat
    10201 agaaactttg taggctatga ccaagtgagt catagtacat ctgaatttga tgtgaccaag
    10261 tatttacagg ttggggttaa tgaaattcaa attctagtga tgaagtggtg tgatggtacc
    10321 tactttgaag atcaggataa gtggcgaatg agcggtctat ttcgtccagt gtatcttctt
    10381 caacgaccaa ctatgcatct gacaagttat caactacgga cgttgactga tcctaaaaaa
    10441 ggaagcggaa cattaatggt ttcttttcaa cgatttactc ctattgaagt atcgttacct
    10501 atttcttacg aattattcca tcctgatgga cgtctcatag cgaaagggga gtgttactcg
    10561 gaacaacaaa taaatttgga tgttgaagat tgcctttttt ggacagcaga aacgcctaaa
    10621 ttatatacat tacttttaac atgtaatggt gaatatttta aagaaaaagt tggctttcga
    10681 gcactgacga tcaagaatcg taagttattg ctgaacggaa cacctattaa attatatgga
    10741 gtcaactatc atgacgtgaa tcagcaaggc acgccagtga tgacccgaga gcagttacgt
    10801 gcagatttgt tattaatgaa aaaattaaat gtgaatactg tacgaacggc acattaccct
    10861 aaatcaccag atttttatga attggcggat gagattggtc tgtatgtaat caatgaagca
    10921 gatttggagt gtcatggtgt ggttaatcta tatgatactg aagcgaatta tcaactaatt
    10981 gctaatgatc cgacattcga aaagccgatt atggaccgag tgatccgttc tattcttcct
    11041 tatcaaaatc gaagctctat cattatgtgg tctatgggga atgaatctgg ttatggagta
    11101 aattttgaaa aagctcaagc tttagcacgg aaattggatg attcacggtt gattcataat
    11161 gaacgctcga ttgaaccagt tattgaccaa gtgaatgatt ttagtaactt ggatgttatt
    11221 agtcaaatgt atcccccact ggaagatgtt catcgtcatt gtcaaagaag tgatactgaa
    11281 aaaccttttt ttatgtgtga atatagccac gctatgggca acggtcctgg agatcttaaa
    11341 acgtacttcg atttgattca acagtatgat tcctttcttg gcggttgtgt ctgggagtgg
    11401 actgatcatg caatcaatag aggaacttta gaaacgccat cttatttata cggtggtgat
    11461 tttggtgaaa aatatcacga cggcaatttt tgcgtagatg gtttattgac cccagatcgg
    11521 caattaacag taggtgcatt ggagtaccgt aatattcatt cgcctattca actgattgct
    11581 gtagatgagg agctgcaaga agtaaccttg agcaatataa ctgcttttac agccggttca
    11641 gcatttaacc tttctcttga atggtatata gatggaaaaa aaacagttta tgaagtaatg
    11701 aatcctttca tacttgagcc tggcaaaagt tgttcattgc ccatcacagt acctacaacg
    11761 attcatggtg ctcatacggt tgctgtttcg ctatctgttt ataaaaatga tgagctttat
    11821 ggacagcaac agctctttct taaaaaagaa aaaatgagat tgccaagaac tgctcatcat
    11881 aatgatgcac cacaaatttc agtaaaaggc acagagctga taatcaaagg agaatccttt
    11941 atttatatat atcaattagc aaaagctgcg ttcacttctg taaagatcaa tcaaaaggaa
    12001 cttttggaac gtcctactca attttcaatt tggcgtgcac caacggataa tgatcgtaac
    12061 ttagtaaaca aatggaaagc agctggatat gctgaaatgt ctttagaaat cagaaaaaaa
    12121 gactggaaat tcgtagatga tcatctcctg atcgaaacgt cttatcgagg agttattcca
    12181 ggattacagc caatttttac aatgcacata cagttgaaaa taaatggtgc aggcgtaatc
    12241 aaccaaaaag tatcagtgga gaaaaatccg atttttccag atttccctcg ctttgggatg
    12301 gactggccgt tgaatgatac tttttcgaag gtttcttatt gtggctatgg gccgtatgaa
    12361 agttatcctg ataagcacta tgctgcgatg tttggtattt atgagatgga gattgaggaa
    12421 tttgatcagc catatatcaa accacaagaa tatggtaacc gctggcaatg tgattgggta
    12481 tcaatcaaaa atcatcaagg atctaccatg acggtttatg gaaactctaa tttttctgct
    12541 ctgccttata gtcaagctca attaaccgaa aagtcacacc attatgaatt aataaaagaa
    12601 aatagaactt ggttcaattt aagttataaa caaaatggta tcggctcaca cagttgcggt
    12661 ccttatttag aagatcgttt ccgttttatg gaagatactt ttgactggaa tatagtgatt
    12721 actttcaaag gagaaaatag atgaaagaaa caaagatcaa tcaagtcaaa aaaaaattat
    12781 ctcgttatca agaagttgtt tatcgaaacc attgcttaaa atggtcaaaa aataagctga
    12841 atgttcgttt taatggatta ttttatcgtt tcgaacagtt agaagaagtc tggaaaccgg
    12901 taacgaattt ccaatcatgt cctgtacagc tcataaatga tccaaaagaa acatacgatt
    12961 tatgtataac acacctttat aaccagcatt tgaaaaatga cggattttat ttaaaggtta
    13021 ctaatgacaa tcaacttacg attgaatcag caaaacttcg agggtttcaa tatgctatgg
    13081 aagccttatt agagagtttt ttttcggtag gagatcaatt attattaccg gaattgattc
    13141 tgaaacatga accatcagtg aaaattcgag gaatcattga agggttttat ggtatcccct
    13201 ggacacatga aatgcgcctc tctctttttt catatatgaa agataaccaa ttgaatactt
    13261 ttatgtatgc ccctaaagat gatgaattat tacgtaaaaa atggcgtgaa ctctacgatg
    13321 cgcaagaatt agacaaattt aaggagcttt tatctgctgc tgaggctagc aatatcgatt
    13381 tttggtactt aattagtcct ggaaatgata ttgatattac gtgtgaagaa gacattcaag
    13441 ttcttctgaa aaagttagaa caactgattg agcttggcgt atttcaattt ggtctattaa
    13501 tggatgatat tgactatcaa ttaaaaggtg ctgctaaacg ccgttttcga gagccagcat
    13561 tcgctcatgc ctatttagtg aatcgagtag aggaatatct tagcactcgg ttgtccaatc
    13621 atgaattagt catttgtcct acagaatatg ataatcgtca tggttctcgc tatttagcaa
    13681 cgttaagtca agaaatacca gaacaattac cgttcttttg gactggccca agcacgttag
    13741 cggcgtcaat ttctacagaa gagctgcagg aaatggcttc tgtctatcaa cggccgatgc
    13801 tgatttggga taatattccg gtaaatgatt atttagagga taaagaacta ttgttcatga
    13861 gtccatatga gaatcgaaca ccgaatcttt ctaaggagag ataccaggtt acaggagtag
    13921 tttcgaatcc aatggctcaa ttagaagctt caaagtttac gatcaatagt atggctaatt
    13981 acttatggaa ctgtgagcgt tttgatcctt tggaaacttg gacgtcagtc gttgaaaaag
    14041 tagttggaag taaactacaa ccagcttatc ttaccttaac caatgctttt ccaaatcatt
    14101 acacaagcag tctgctttca gatgaagaat tactgctagc caaagaccca gaatgggtca
    14161 caaaagaaat ggctgcttta gtccaagcag taaaatggat ccagcaagaa caacatacat
    14221 ctagattgag aacagaattg gagccttggt tacaagcaat cacagaaagt tggactttct
    14281 ggcaagaatg gcaattaaaa aaagatccaa aagaagcaga agaatggttg gctaagaaaa
    14341 aaacacaccg cataggacgt gatttagtaa ctgcccattt agagcaaatt atcaaaagtt
    14401 agatatctta aaaaataaaa agcaagaaaa aggagaacaa aatggtcaag agattaatta
    14461 gtgcaaacta cagtgatgtc aagaaaatga cgtcaaaaga gttgaagcaa tccatcaaag
    14521 cgagtgaagg acgggtgatt gtttgtgaaa cggttgctaa tactcttcca caatctggag
    14581 aaattacgaa tgcagaagtt gcgtcagcat ttggtgcaga tttgattctt ttaaatggtt
    14641 tcgattgtta tcgtcctgca gtttttggac taccaaatgt gacgattgag aaggtttttg
    14701 atctacagca aacgattgaa aacccgattc ctaaattaaa agaactagtc ggtcgtcctg
    14761 tgggaattaa tttagaaccc attgccccta aaacaaatat gatgagtgag aaagtagaaa
    14821 tcagccaagg aagagcaagc tctgttgaaa cgatacaaaa agcagaagaa ctaggagtcg
    14881 attttatttg ctttaccggt aatccaggca ctggagtaac caatttagaa attactaaat
    14941 ccgtaaaaat ggcaaaaaag tatttttcgg gattgattat tgctgggaaa atgcatagcg
    15001 ccggctcaga agagccagtt gtgaataaag aggcgattat ttcttatgcg gaagcaggcg
    15061 cagatatttt actagttcct tcagtagggt ctatcccagg ctttttagag caagacctaa
    15121 ttgaagcggt tcggttggca aaaaaatatg atttgttaac gatgtctgca atcggtacta
    15181 gtcaggaaag tgcccgacca gaaacattgc ggcaattagc cattatgaat aaaagttgtg
    15241 gtgttgattt acaacatatt ggagatgctg gatacggggg attggcacca gcagaaaata
    15301 ttttcgaaac ctcggttgca attagaggaa tgcgacatac catcaactgc gttagccgct
    15361 cgatcaatcg ctaacaaaat taaataaaaa atggttaaat tgattattta agtgggaaca
    15421 tacttgagat atcagctaac ttctgtcact ttaaaaaagg gactgtgaca gaagtgaaaa
    15481 tagacaaaaa atatccgaac aagagactag gatagcagaa aaactatcgt tttgcaacga
    15541 ggaccaactg gaccgtagga gcaattctct tattgttcgg atatttcgct tgttcaagga
    15601 cttatgtctg tagtgccctt ttttggtagg aaaaatggta gggaaccata tcatttttaa
    15661 tgaaaatcaa gcatttcaaa agttgaa
//
LOCUS       DACGMI010000066        15244 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.068, whole genome shotgun sequence.
ACCESSION   DACGMI010000066 DACGMI010000000
VERSION     DACGMI010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.068"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            168..362
                     /locus_tag="IXT46_002376"
     CDS             168..362
                     /locus_tag="IXT46_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948273.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="IXT46_002377"
     CDS             631..930
                     /locus_tag="IXT46_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948274.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="IXT46_002378"
     CDS             complement(1027..1461)
                     /locus_tag="IXT46_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4948275.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="IXT46_002379"
     CDS             complement(1693..2403)
                     /locus_tag="IXT46_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAQ4948276.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="IXT46_002380"
     CDS             complement(2393..3253)
                     /locus_tag="IXT46_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAQ4948277.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="IXT46_002381"
     CDS             complement(3258..3896)
                     /locus_tag="IXT46_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAQ4948278.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="IXT46_002382"
     CDS             complement(3911..4210)
                     /locus_tag="IXT46_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4948279.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="IXT46_002383"
     CDS             complement(4253..5737)
                     /locus_tag="IXT46_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAQ4948280.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="IXT46_002384"
     CDS             complement(5757..6218)
                     /locus_tag="IXT46_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4948281.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="IXT46_002385"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="IXT46_002385"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAQ4948282.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="IXT46_002386"
     CDS             7521..8291
                     /locus_tag="IXT46_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4948283.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="IXT46_002387"
     CDS             complement(8564..9391)
                     /locus_tag="IXT46_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4948284.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="IXT46_002388"
     CDS             9959..11194
                     /locus_tag="IXT46_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAQ4948285.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="IXT46_002389"
     CDS             complement(12193..12453)
                     /locus_tag="IXT46_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAQ4948286.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVTHLNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="IXT46_002390"
     CDS             complement(12480..13781)
                     /locus_tag="IXT46_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4948287.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="IXT46_002391"
     CDS             complement(14073..14531)
                     /locus_tag="IXT46_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAQ4948288.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..>15244)
                     /locus_tag="IXT46_002392"
     CDS             complement(14544..>15244)
                     /locus_tag="IXT46_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAQ4948289.1"
                     /translation="KELQREIMPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITK
                     NFPSNIPNNYLEYYLYPDMVVEHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVL
                     NFNFGEHGQYIVDIAISLLNDDRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEP
                     ITLRKPISDFHKGLMEAQVAVEKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILD
                     EMIKVNKKYWPALK"
BASE COUNT         4876 a         3105 c         2365 g         4898 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgcccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatacttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcaaatgcgt
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacgac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttat
//
LOCUS       DACGMI010000067        15220 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.069, whole genome shotgun sequence.
ACCESSION   DACGMI010000067 DACGMI010000000
VERSION     DACGMI010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.069"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            71..2110
                     /locus_tag="IXT46_002393"
     CDS             71..2110
                     /locus_tag="IXT46_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAQ4948290.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2219..3370)
                     /locus_tag="IXT46_002394"
     CDS             complement(2219..3370)
                     /locus_tag="IXT46_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAQ4948291.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(3524..4054)
                     /locus_tag="IXT46_002395"
     CDS             complement(3524..4054)
                     /locus_tag="IXT46_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948292.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4153..4503)
                     /locus_tag="IXT46_002396"
     CDS             complement(4153..4503)
                     /locus_tag="IXT46_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAQ4948293.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(4660..6189)
                     /gene="ahpF"
                     /locus_tag="IXT46_002397"
     CDS             complement(4660..6189)
                     /gene="ahpF"
                     /locus_tag="IXT46_002397"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAQ4948294.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6199..6762)
                     /gene="ahpC"
                     /locus_tag="IXT46_002398"
     CDS             complement(6199..6762)
                     /gene="ahpC"
                     /locus_tag="IXT46_002398"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAQ4948295.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(6906..7568)
                     /locus_tag="IXT46_002399"
     CDS             complement(6906..7568)
                     /locus_tag="IXT46_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4948296.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            7752..9398
                     /locus_tag="IXT46_002400"
     CDS             7752..9398
                     /locus_tag="IXT46_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAQ4948297.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            9389..10471
                     /gene="uxuA"
                     /locus_tag="IXT46_002401"
     CDS             9389..10471
                     /gene="uxuA"
                     /locus_tag="IXT46_002401"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAQ4948298.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(10579..12132)
                     /locus_tag="IXT46_002402"
                     /pseudo
     CDS             complement(10579..12132)
                     /locus_tag="IXT46_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
     gene            12280..13421
                     /locus_tag="IXT46_002403"
                     /pseudo
     CDS             12280..13421
                     /locus_tag="IXT46_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(13547..14626)
                     /locus_tag="IXT46_002404"
     CDS             complement(13547..14626)
                     /locus_tag="IXT46_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4948299.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(14729..15169)
                     /locus_tag="IXT46_002405"
     CDS             complement(14729..15169)
                     /locus_tag="IXT46_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4948300.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
BASE COUNT         5243 a         2811 c         2762 g         4404 t
ORIGIN      
        1 tttattatgt tagaataaac aggtataaat agtgaaataa aggaatgaca agcaagagaa
       61 ggaggaaaaa atgaaaagaa gtgacaagca cggcaaaaat cgaacaggcg cttatattgc
      121 cggcgcagtg atcttaatag cagctgcggg tggcggttat ttttactacc agcactatca
      181 agaaacccaa gcagtagaag ctggagaaaa gacagttgag caatttgtcc aagctttgaa
      241 caagggagat tataacaaag ctgcagaaat gacatcaaaa aaggcggcaa ataaaagtgc
      301 attatctgaa aaagagatct tagataaata ccagaatata tacggtgctg ctgatgtcaa
      361 aggacttcag atatcgaatc taaaagtaga taaaaaagac gattctactt acagtttttc
      421 atataaagca aagatgaata cctcattagg tgaattgaaa gatctttctt ataaaggaac
      481 attagacaga aatgatggtc aaaccacgat caactggcaa cccaacttgg tttttccaga
      541 aatggaagga aatgacaaag taagcctgac cacacaagaa gcagcaagag ggaatattat
      601 agatcgaaat ggtgaaccat tagcaacaac aggcaaacta aaacaattag gagtcgttcc
      661 aagtaaactt ggagatggag gcgaaaaaac agccaatatc aaagcgattg cttcctcctt
      721 cgacttaaca gaagatgcta tcaatcaggc gatttcacaa agctgggtac aacccgatta
      781 ctttgtccca ttgaaaatca ttgatggagc aacgccagaa cttccagctg gagctaccat
      841 tcaagaagta gacggcagat attatccttt gggtgaagca gctgctcagc tgattggtta
      901 cgtgggagat atcacagcag aagatattga taagaatcca gaattaagca gtaatggaaa
      961 aatcggtcgc tcaggtttgg agatggcttt tgataaggat cttcgtggga caacaggtgg
     1021 gaaattaagc attacagatg cagacggtgt agagaaaaaa gttctgatcg aacatgaagt
     1081 tcaaaatggc aaagatatca aattgacaat cgatgcgaag gcacaaaaaa cagcttttga
     1141 cagtctagga ggaaaagctg catcaactgt tgcgacaacg ccaaaaaccg gtgatcttct
     1201 tgcgcttgct agctctccaa gctatgatcc aaacaaaatg acaaacggga tctcacaaga
     1261 agattacaaa gcttatgaag aaaatcctga acatccattc atcagccgat ttgcgacagg
     1321 ttatgctcct ggatctacgt ttaaaatgat tacagcagca atcggtctcg acaacggcac
     1381 tatcgatcca aatgaagtgt tgacgatcaa cgggcttaaa tggcaaaaag acagttcttg
     1441 gggatctttt caaacaacgc gtgtcagtag tgatgtatca caagtagact taaaaactgc
     1501 tttgatctat tccgataata tatatgcggc acaagaaacg ttgaaaatgg gtgagaaaaa
     1561 atttcgtaca ggcttagata aattcatttt tggtgaagac cttgatttgc caattagtat
     1621 gaatccagca caaatttcta atgaagatag ctttaactca gatatcttgc tagctgatac
     1681 tggatatgga cagggcgaac ttctaattac tcctatccag caagcagcaa tgtattctgt
     1741 ttttaccaac aatggcacac ttgtctatcc taaattgatt gcagataaag agacaaaaga
     1801 taagaagaat gtcatcagcg aaacagcagt acaaacgatc gtgccagatc tgagagaagt
     1861 tgtgcaagat gtaaatggta cagcacattc tctttctgct ttagggattc cgttggcagc
     1921 gaaaactggt acagcggaaa tcaaagaaaa acaggatgta aaggggcaag agaacagttt
     1981 cttgtttgct ttcaatcttg ataaccaagg ttatatgatg gtcagcatgt tggaaaataa
     2041 agaagatgat gattcagcaa ccaaacgagc atcggaacta ttgcaatacc tcaaccaaaa
     2101 ttatcaataa aaaattgctt tttaagtaca gtaaaaggac tgtggcgtta tcgtcacagt
     2161 ccttttttca aataaacggt tttcacgatg tctctttcac aacttctttt tgatttactc
     2221 acacttcata aacttttttt gtaaaatatt tgagaacaag tggagaaata agtgtactta
     2281 ataaaatcac gataactaaa ggtgaatagt actgtggttc gatcaattga ctttgctgtc
     2341 caatttgtaa aatgatcaaa gccatttctc cacgcgaaat cataccagca ccgaccatca
     2401 atgaactatg ttgagaaaaa ccggcaatct gagcaccaaa ataacctcca agcaatttgg
     2461 tcaaaatcgc tacaagcgtc aatatagaaa taaagagtag ttgttcacta aagtcagaaa
     2521 aatcaacttc taatcctaca ctgacaaaaa atactggtat aaatactgca tatcctaaag
     2581 cctctacatt gtggtatact tcttctttaa cctttgtctg actgacagct atcccagcaa
     2641 aaaaagcacc aatgacagag ctaagcccaa caagatccgc tacgtaagac attcctaaac
     2701 aaataactag cgatacgatg ataatagaag aatttgcgta cactttttct gcaaatgaaa
     2761 gtaggaaagg cgcaatccat ttgactaata agaaaataaa aacaaaataa attagctgtt
     2821 caatcaaaac aagcggtaaa gaagcattgc tagaagcttc ccccgttaga aaagataggc
     2881 tgaaacttag aactaaaacg actaaaatgt catctaccac agaagcaccc aaaattgttg
     2941 atccttcttt tgtattcact acgtttagtt cttttaatac ttctactgaa atactgacag
     3001 aagttgccgc aagaataatc ccaaagaaaa tcgcttcatt tcccgaaact tggaatgctt
     3061 tgcctgtcaa ccagccaaaa acaaccggga agatgatccc aagcaaagca acgaacatac
     3121 caggtcggaa atattttttc aaaagagata aatcactttc cagaccagct aaaaacatta
     3181 ataagatcac accaatctcc gaaaagtcat ggactagaat atcaggtttg acccaattca
     3241 atccagcttg gcctagcaaa acaccaacaa gtaattgtcc aatcactgct gggataccta
     3301 atctccgcga gatatgtgag ccaatcgttg ttgaaatcaa tatcaggcat aaaataccaa
     3361 taaattccat tctcatcatt cctttgtata aaatatagcc cgaacttagc ataacataca
     3421 ttattgaaaa aataggaaaa tatactcaca aaaaaaccaa caatccaaaa gatttttttg
     3481 gattgttggt ttttatacgg tctattttaa taactaaaaa tgattaacgt atagtcattt
     3541 ttcttattct gatgaaattg ataatctcct ggatgcccat gaaaatcaaa ataaagccga
     3601 atatttggaa tagaagcatc aaacttttga atggattgaa caataagacg aatccgccaa
     3661 tcaacaacag aatactacta taaacactcc aacttttagc ttttgtattc atgctgaaga
     3721 acaactggaa caagctgttg atgataacag ctaatccaag aagaatcggc aggatagaaa
     3781 cgattgcagg tgcaaaagca tagacgatca gagctaagat caggaaaaaa agaccactga
     3841 acagaccgat actccaagaa cctgttttcc ttttaaaacg gtaagcctca aaaagattca
     3901 acaacccaag caaaacaaga taggcggtga tcagataacc gataaaatga aaaacagcag
     3961 aagggtttag cacaatcgca atcccagaaa taatataaac agcagctctt aataaggcgt
     4021 atttttgaat attttgttta atcgtctcaa acatataaga aaacctcctt tgacttattt
     4081 taacgtgaac tagtcatttt accaaattaa atgttacaaa atgagcgaag gagaagaata
     4141 tctctggaaa aatcaacttc tgaggatctt ttccattttt ttgccttttg ctagctcatc
     4201 gatcatttta tctaaataac gaatttcttt catcaagtta tcctcgatgt cttctactcg
     4261 tacaccacaa acaacacctg taatcaagga acgtgaagga ttggggacag gggcttccgc
     4321 aaaaaattgt tcgaaagtca cttgtttttg tagttgatat tctagttctg tttgggaata
     4381 acccgtcagc caacaaatga tttcatctac ttcctctttt atacgatctt ttctctccgc
     4441 ttttgctaca tacataggat aaacgcttgc aaaacttgtc gtaaaaatac gattttgcgc
     4501 cataatcagt cacctttctt tttttcaaat tatttactac ttatagtata taagaaaaag
     4561 agaagaaaaa gcgattattc aaaaaaacaa aaaggattgt gacaaaattc ttgtcaccat
     4621 ccttttttcc gctctctgac tttttacaat cttcatagct caagtgcgca tcagataatc
     4681 gaatgctcct aaagctgcag tagctcctga acccattgaa acaatgattt gtttgtatgg
     4741 actatctgta caatcaccag ctgcgaaaac gccggggata ttcgttgcgc catttttctc
     4801 ggtcactatt tcatttcttg gattcatttc gatcgttcca tctagccaat ccgtattagg
     4861 gagtaagccg actagaatga atactcctga aacagctagt gtatgcatct ccatcgtacg
     4921 gcgatcgata taggagagag attctacctg attcgtaccg ctgatttctt tcgtcgctgc
     4981 atgtttgata acagtgacat tcgcaagaga gactagttta tcctgtaaga tttgatctgc
     5041 ttttaattct ggtaagaatt ctagaacata tacatgtttt gctaacccag ccaaatcgat
     5101 tgctgcttca acaccagaat taccaccacc gataacagca atctcttttc ctttaaataa
     5161 agggccgtca cagtgtgggc aataagcaat tcctttattt ttaaactctt tttcgcctgg
     5221 tacattgata gaacgccagt gcgcacctgt cgcgatgatg gcggtttttg ctttaagtga
     5281 tataccgtta gctaagccaa tattaataaa atgttgctct ttatttaagg aaacggcctg
     5341 ttgattcatc ataatgtcga tagggtaact acgcacatga ctttctactt gctgcatcaa
     5401 ttttggacct tctgtgtaag aggtaccaat catattttca atccctagtg tttcaacgac
     5461 ttgtccgccg aaagaatcag cgacaagtcc tgtacggatt cctttacgtg ctgcatagat
     5521 agctgcacta ctagctgctg gtccaccgcc aatcactaat acatcataag gttctttttc
     5581 aaacaactct tcttcaatca aagggccagt gattttttca acaatttgtt cgatcgtcat
     5641 gcgtccgcta ctaaattctt ctccatttaa aaacacagtt ggcactgcca tgattttttt
     5701 atcatcgatt tctttttgga acatcccacc ttcaatcatc gtatgagtaa tatttggatt
     5761 taatacagct aatatattca atgcctgtac aacgtcgggg caattatgac aagtcaagct
     5821 aacataactg tcaaaatgca atgtttgtgt tatttttttg attttaagac tcaaagattc
     5881 actgattttc ggtgcccgtc cactaatttg taacatagcc agtaaaaaag aggaaaattc
     5941 atgaccgagg gggataccag caaaaacgat tccactttct ttgccaactg gattgataga
     6001 aaaactaggt gtgcgcatcg aatctctttt ttcccaagag attttaggag acatttctgc
     6061 tatttccttc gtaaattcag ctagtttttg actattttca ctattatcca aactaacaga
     6121 aaaaacaata ggagattcaa tcagtgctaa atattgttcg agattttgtt tagtttcttt
     6181 gtctaacata tccaccacct aaatctttcc aacaagatca aaacttggtt tcaatgtttc
     6241 gccactttct ttccattttg ccggacaaac ttcacctggg tgggtacgta catattgagc
     6301 agcgcgaatc ttatcaatca gtgcactagc gtcacgaccg attccatctg cattgatttc
     6361 catagcttga acgattccgt ctggatcaat aataaatgtt cctcgctgag ctaatccttg
     6421 ctcttcatcc aaaacatcaa aaatacgaga aatctgatga gacggatcac cgatcatcac
     6481 gtattcgatt ttaccgatag catctgatgt atcatgccat gctttgtgag taaagtgggt
     6541 atcggtagag caagaaaaga cttcaacacc taaagatttc aatgtactgt attgttcttg
     6601 taagtcttct aattcagtag gacaaacaaa agtaaaatca gctggataga agcaaagaat
     6661 actccagttc cccataagat ctttttcact gacttctaaa aattctcctt gatgataagc
     6721 atgtgcatta aattcttcga tttttttccc aatcaatgac atagtaaaac ctccaataat
     6781 aattatttat ttataattat tgtaatttag ttggagttgc aaagtcaatg gatattttgt
     6841 tatttaataa agattactca aaaacgaagg ttaattataa aaatagaaga ggtcgcaaga
     6901 aaatgctact gctggaaata ctcgggataa cgttgagtaa cagtttcctg ttctttcagc
     6961 atcatgtgta agtgcaatcc cgtttgaaat cgagcttctt ctggtttttt atcaactaaa
     7021 gccttgagta aatcataatg ttgttccatg atcgtttccc atggaagccc ctgaatggtc
     7081 actcgtaacc agcggaaacg ttctaaatgg gtattatggt catctaacca gttccaaact
     7141 tcttttcttc ctgcaatttc gaaacaagct tcatgaaata aattatctgc acggaaaaaa
     7201 gcgcgttcgt catttatttt gactgctttt tcttgttctt ctaaaatcgt ttctagcact
     7261 attcgtgttt gtgtgtccaa tttggaacaa cattcaatca tgatttgctc ttccaactgt
     7321 tctcggacaa agcgagcatt ttctgcagaa acaagattaa ttttggaaac atacgtacca
     7381 ctttgaggta tcgtatacac gagttcttgc tgacgtagtt gaatcaatgc ttcgcgaatg
     7441 ggagtccggc cgatagcaag atgttcctcc agtgcctttt cagatatttt ccttccaggt
     7501 tctaagtcag catagataat ttgtttacga atcgcttgat aagcttgtga ttgcaagctg
     7561 cttttcatct ttattcctcc aaaatcattt ctatgaacgt agtataacag aagaggtctg
     7621 aaaaacaatc tggtatgtca cattaactag taaatttgta taaatagtaa aattttggtt
     7681 gacatagcga tttttattgc ataaaattca cttgaataca aaaactaata tgttagttta
     7741 ggaggggaaa aatgattgat ttaaacaact ggaggaactt tatccctgaa ttatctcaaa
     7801 aagaagtaga aatacctcat tttgaccgtg catcattaag agaaaatgga caaaaaaatc
     7861 ctgtctggat ccatttcggt ggcggaaatc tttatcgagg atttcatgca gaaatcgctc
     7921 aacgtttagc ggatctaggc gaattgtcca ctggtgtcat tgtttgtgaa acattcgatg
     7981 aagaaataat tgaaagggct taccaagatt ttgatgattt gattcttgaa gtggtcatgc
     8041 caagcagtgg agagttcgtc aaacgtatat tagctgcgac agctgacagt ctgtattgtc
     8101 atccagattg ttctgaacac tttgataaga tgattcgaca ctttgaaaat cctagtttac
     8161 aattagttac ttttgctatt actgaaaaag gttatcgatt gaaagataca aataataaat
     8221 atataggacc gattgcagtc gatataaaaa atggtccaaa gaagccatca catacaatga
     8281 gtattcttgc tgtgctactt tataaacgtt ttttatctgg agcttggccg attgcacttg
     8341 tctctacaga taatttttca caaaacggta gtcaattacg tacttctttg ctaacgatcg
     8401 caaaagaatg gcaaaaggaa ggttatgtac aaaatacatt tatccaatac ttatcgaatg
     8461 aagaaattgt tgcgtttcca tggacgatga ttgatcgtat caccccgaat ccttccttgt
     8521 cagttagcaa aatgttggca aaagagggct tttcaaatat gtcgattttc caaaccgcaa
     8581 aaggaaataa tattgctcca tttgtcaata cagaggacat ccattattta atcatggaag
     8641 atcattttcc caatggacgt ccgaaattcg aaaaagctgg ggtattcttg actgatcgtg
     8701 caacggtaga taaagcagat acgatgaagg tgacgacttg ccttaatcct ttgcatacgt
     8761 ctttagctat tatgggttgt ttactggggt ataggagcat agctgaggag atgaaagatc
     8821 cagatttatc gctgctagtt tctgaaatcg ggtacaatga aggcctccca gttgtggagt
     8881 ctccaggtat cattgatcca aagatctttc tggaagaagt aattactgtg cgcttttcta
     8941 atccaaatat tcctaatatg cctcagcgaa tcgccacgga tacctctcaa aaggtggcga
     9001 ttcgttatgg tgagacgatt aaaaaatata tggaaataga agttaaagac ccgcagacac
     9061 ttgtattcat accattgact ctcgctgctt ggcttcgata ccttattggc attgatgatc
     9121 aaggaaaacc attcatcccg agtccagacc cactattgac agaccttcag cataagcttt
     9181 ccgatattca actgggtacg caagatacat cacatattca tgagaaaatg gctcctattt
     9241 tgtcaaataa agaaattttt ggtgtagatc tttaccaagc agagcttggc agaaaaatag
     9301 aagaaatgtt catcaagatg gtagcaggac caaatgccgt acgaaaaaca ttacaggatt
     9361 acttacaaga acatggagga aatttatcat ggaaatgact tttagatggt acggatcaca
     9421 ggaagaaaag attaccttag atgaaatcag acagattcct gcggtcaaag ggattgtagg
     9481 cacattgatg gatataccag taggagaggt atggcctagg gagaggatca aagaactaaa
     9541 agaagaaatt gagtctcgtg ggttaacact aaaagtaatt gaaagcgtca atgtgcatga
     9601 tgccattaaa attggattac cttcccgtga gcagtatatc gaaaactata agcagacaat
     9661 ccgaaacttg gcagaatatg gaatagaagt catctgctat aattttatgc ctgtatttga
     9721 ctgggtgaaa tctgaccttg actaccgctt agaagacggc tcatccacgt tagcttttat
     9781 atctgatgat attccagatg atccaagaga aatcgtcgcg cgcatcgaac attccagcaa
     9841 tgaatttgga ttgccgggat gggaacctga gcgcttagct cctatcaaat ccttgcttga
     9901 agcctatgca tcagtagacg aagaaaaact tcgagaaaat tttgcctatt ttctccaatc
     9961 aatcatccca acatgtgaag aggtaggggt caaaatggct gtacatccag atgatccgcc
    10021 atactcgatt tttggattag ctcgaatcgt aaagaatcga gaagatttag attggttgtg
    10081 tcgcatagta gacagccctt ataacggaat cactctttgt acagggagta ttgcagaaga
    10141 tccagaaaat gatgtatatg ggattttagc agaattttgc caaagagatc gaatcccatt
    10201 tgcacatgtt cgaaatatta aatttttagc taatcgagat ttctatgagg caccacataa
    10261 atccgaatac ggttcattag acatgtaccg catactaaaa acaatgtatg acaacggatt
    10321 taacggatac atccgtcctg atcatggaag aatgatctgg aatgagacag gaagaccagg
    10381 atacggctta tatgatcgag cattaggtgc tgtttatcta aatggattat gggaagcaat
    10441 cgaaaaagga aacaaaagta aagataatta gtgaaaaaaa ctgtaatttt attatgtaaa
    10501 taagaaggat gttcaaattc ttgatacata aatccggagg ttgttaataa gcattcggat
    10561 ttatgtatct tatttggtct aggaagtaac ttgattttct tttttcgatt gatccatgag
    10621 tgcttcttct tttaattcaa agatatattc tgagatcctc ataatcactt ttttccagtc
    10681 ttctggtgtg atgattcctt ttaaaatata gatttttttg atatgagaag gcaattgttt
    10741 caaagggcag tcgctgataa cgatgttgca gttctccata aaatcatttt gtattttgat
    10801 cgattcattt gaaaaaattt gttctatctt aacgatcaga tctttactga tataaaaatc
    10861 acgcgtatag ttcacaccaa tcacaattcg cggctgtttt ttgtagcgat catacaaatg
    10921 tactaggtct tcaaccatcc attgcacatt ttccttttct aaaataactg gtaacaagtg
    10981 ttgattttgt tctctgaaat ccatataaaa ttgttcaatg gcggtttgga cttctttcaa
    11041 tacgctatgt tcttgataaa gcatgaaagt aggaaggggc gtatttggtt gattgaagtt
    11101 aagaaatcca ttataaagtt tatttcgtgc gaatgccaat gagtaaagaa tcttttcttt
    11161 ttcaggtata aacaaatcaa atacagtaca aagggactcc accatttctc ttgaataaag
    11221 aacatgagga acgtttgctt tttttaaaag tttgtattgc tccaagcttg tttcttccga
    11281 ttcgattttc gtgatagaaa gtcgagctaa aatattcact aagatgcgtt gttcgcgaca
    11341 aattggcaga ttaggtcgca aaatatctac agagagatca ataaaaaagt caatatattc
    11401 atactctgtg aattcttttt gtacgtcttt cacagaagtt gcaggaaaat tctctttaca
    11461 tatttttaat agaaaatata atttatctat cataccgcta tttagtcggt caagtacttc
    11521 ttttttaaaa aaagtattca tcataaaagc cactacttgc ggatcttcat cataaaattc
    11581 tgtagcagta cttgaaaaga tgttccaata aatatctaat gctgcatatt gaatttgtac
    11641 ctcttttcca gaaaaagact ttctgccatt attagaaaag gagatagaca aaccgtacta
    11701 tgctaaaaat gcattaatct ttttcatttt cgtatacaaa taagaggcac tatagtttgt
    11761 ttgctgactg aaactgataa tcgaatttgt ctgacagctg aacaaagaag tcaagatctg
    11821 ataactgact gattcgttgc agtatcttcc aaatagacga taatagcagt aagccggatc
    11881 aattccttca aaattcaact ttaaaaaagg tttttgctta tcaatatgca gttctgttag
    11941 attgagacgc tcaaagtctt gttctaattc tttgatgtat agtaaaaaat ttgattcaga
    12001 catatggaaa tgatctgcta aatattgtgt agtaataaag aaacgatgtt cagataggaa
    12061 aagaaaaata tctaattttg tattgctttt tttcttcaag ataaacgttt taatcgcttc
    12121 ttgagtttgc atgaaagagg ctccttttta cttaaattgt taaaacttga aaatattact
    12181 gtttttttca taaatttaga caaaaaaaca gtaaacatat aggtagaatc tctactatct
    12241 tatttcttgc atacaaaaaa atcaaggagt gagagagtta tgagatattc aaccatctta
    12301 atatcaacat ttgcagcctt aagcttatcg cttactataa atcagacagt ccacacagag
    12361 gagacagaaa cagccaaatg gacagaaacc aagtgggcca acgtcaatcg aattaccttt
    12421 caggatgaat tttcatcctt caattcagga gtcgcaaaat taagaaaagg acaaacagcg
    12481 accatcaaag caaaaattga ctattcggga gacttagcac ctatactaca atcagctgtt
    12541 acatttgaga atgttgatcc cactttgtcg attggctatg acgagaacac tttgactatc
    12601 caacacaagc aagcgatatt taccttcacc gttacattaa atcaggactt gttaaaacca
    12661 gcgcttttta ctgtcaaggt atcagatgga ctaccgaacg atcatcattt aacgccgtat
    12721 agtcagcggc agacaattga gcaagattca gccatcgact caggaggaga tcttgttgaa
    12781 gaaccaacag ataaaccaga aaatgaaaat aagccagaag taccgcctac agaaaatcca
    12841 gacggagaac agaaaccgga aatagaacct ggagaagaac ccgatacaga aactcaacca
    12901 gagccagaca ataaatcaaa acctgaaata acccctggag aaaaaccaga tgtaactcca
    12961 gaaccagata cggattctgg aaaccaaaca gtaccggaaa caaatccaga cacagataat
    13021 gaaactgaaa atccagaaaa accagaggta gatccagaag aaaaaccaga tgtgactcca
    13081 gaaccagata cggacgcaag agaccaagga ataccagaaa aaataaacaa aaaaacaatt
    13141 caagaggatg gaaaaaaaga gagtaaaaaa tcaaatctag caattctaaa aataaatgaa
    13201 gagcagctga ataaaaaatc acgaatattt gatagcgccc aatcagctga aaccttaaaa
    13261 agtagcaagg atacaacctt tgctgtcctg aaacgaaaaa taaacagcta ccaaaatccg
    13321 gagagtcaca aaacaaagtt atactgtgga gcggaatcat tctattaagt atagcaacaa
    13381 tgctttctgc aaaaagattt aaacaaaaca gatctctcta acatttgaat aatgtctgtg
    13441 aacgcatttt tcaaataaaa agaaatatcc agaaaatgac cccaaaatac cagattgaaa
    13501 tctgatattt ggggtcgttc atactttatc tttcttcata tttattttaa gggatatctg
    13561 tttcttttgg aagatggttc gggatctttt tcactttcaa tacatctaaa aagaaggtaa
    13621 agatcggaat gccgacaatc aagccccaaa cgccaaagaa ccgttcgcta acaagtaaga
    13681 ccacaaatgt ataaaaaatc ggcagttctg ttttgctgga catcaacttc ggattcagca
    13741 cataagactc aattagatgg acaatcaaaa tcgtaatcag gatataaaca acatctcgga
    13801 tgcctccttg ggaataagct atgaaagata gaggaataca agaaatgata acacctgcta
    13861 ctgggatcag acttaaaatg aaaatcatga tcgctaaact cagcagctga tgaaagccaa
    13921 atacagccaa ggcgattgta gtgagcaacg tatttaaaag agcgacaaca aattgagctt
    13981 ctaataccaa accaaatgta ttgacaaact tatcggcaaa atagtaaata tcttgaaaga
    14041 accaagaaaa ttcacttttt aaaaacaatc ttgagaatac aattgttttt ttcttttcaa
    14101 tcataaaaaa gaaacttaag atgaatgaca tagcaaacgc cactgccatt tttcctatat
    14161 cctgtaaata gccaagcgca atcgaagcgc cattttgaag ctgttcaaaa aaatcgtttc
    14221 gctcaatata agtatggata tattgtaaaa caggatctgc atcttttggc tgatgctcgt
    14281 aaaaattaat aacggactgg atcatgtcaa atgtttgatg aataagcatc gggatatact
    14341 ttgtgaatgc cagatagata aggtaaacga tcagtgtata aatcatgata gctaaaacac
    14401 ctgtagggat tcggacaaat cgctgaatga tttgaacaag atgaatcatc aaataagtaa
    14461 agataaatgt gagcaaaatg gttgtaatca tacttctaac taagaaaaga acaaaaacga
    14521 caaataataa aacagtgaga cggcgtattt tttcattcgc caaaaaacgc tgataaacgg
    14581 tcaaatcgac aacctccaaa taacaaaaaa taaacacgtt attcattata tgatggaata
    14641 tgaaaataag aaagagcaaa aagaaaaacc gctaaatgac gttatcttat gagttggttt
    14701 tcctcataaa atcgttcatc tagcagtttc agcccttttt ctggtcttga tgaaaattat
    14761 ctagcatttt tcgggtcaga tgttgcagtg tatccaattc ttcctgttca agtggaagat
    14821 aagacttgat cttttgtgga ataccttctg cttgtttttg caacgcagca ccttgagcag
    14881 tcagcgtaac atttacgatt ctttcatcac ccgtttcacg ctgacgatta atataatttt
    14941 tttctgctaa cttttttagt aagggagtca gcgtaccaga atccagacac aaatcatttc
    15001 ctagctcttt cactgaagtc tttttctttt cccataaaac taacatcaca agatactggg
    15061 tataggtaag attcagcggc ttgaggaggg gagtgtagtg tctaatgatt tctttagagg
    15121 cggcatataa aggaaaacat acttgattaa ctaaatatag atcttccatt tttccacctc
    15181 cgctgtttta ctatagtgta tcatagcgga tttacacaaa
//
LOCUS       DACGMI010000068        14568 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.070, whole genome shotgun sequence.
ACCESSION   DACGMI010000068 DACGMI010000000
VERSION     DACGMI010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.070"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..898
                     /locus_tag="IXT46_002406"
     CDS             <1..898
                     /locus_tag="IXT46_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948301.1"
                     /translation="KSLSEYTGIFDEDIYEAFPLERFPIEYEYVHKVNFNEIQKKYKS
                     YFPNLFDNDQLTLRIKDKKNSHSLNIDIVYSALNFMKNTWQDLNSRYTDWGPEKKLLM
                     TAPSKGSLKLEFELANDEQTALFSDEASFSELIDFVDNLMYTPMYDDEELINERKIIE
                     ETVKLYEVIEKNDLSIDFISNDVKLSNISKSSNIKKNLDVLKARVNDKIIENSTLTED
                     IEVSGEVLAANKSKNYFKIKSLALGDIGGVFEKELFKKIKNSEKQITVSKNITACITK
                     QQITNIDTNEIKTKYVMTSFDQ"
     gene            1252..1325
                     /locus_tag="IXT46_002407"
     tRNA            1252..1325
                     /locus_tag="IXT46_002407"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1286..1288,aa:Ile,seq:cat)
     gene            complement(1509..1581)
                     /locus_tag="IXT46_002408"
     tRNA            complement(1509..1581)
                     /locus_tag="IXT46_002408"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1546..1548),aa:Lys,seq:ctt)
     gene            1961..2530
                     /locus_tag="IXT46_002409"
     CDS             1961..2530
                     /locus_tag="IXT46_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAQ4948302.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            2517..3377
                     /locus_tag="IXT46_002410"
     CDS             2517..3377
                     /locus_tag="IXT46_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4948303.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            3567..4271
                     /locus_tag="IXT46_002411"
     CDS             3567..4271
                     /locus_tag="IXT46_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4948304.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            4276..6111
                     /gene="walK"
                     /locus_tag="IXT46_002412"
     CDS             4276..6111
                     /gene="walK"
                     /locus_tag="IXT46_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAQ4948305.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            6108..7424
                     /locus_tag="IXT46_002413"
     CDS             6108..7424
                     /locus_tag="IXT46_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948306.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            7425..8294
                     /locus_tag="IXT46_002414"
     CDS             7425..8294
                     /locus_tag="IXT46_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948307.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            8349..9158
                     /locus_tag="IXT46_002415"
     CDS             8349..9158
                     /locus_tag="IXT46_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4948308.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(9261..9890)
                     /locus_tag="IXT46_002416"
     CDS             complement(9261..9890)
                     /locus_tag="IXT46_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HAQ4948309.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            10060..11352
                     /locus_tag="IXT46_002417"
     CDS             10060..11352
                     /locus_tag="IXT46_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4948310.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(11428..12090)
                     /locus_tag="IXT46_002418"
     CDS             complement(11428..12090)
                     /locus_tag="IXT46_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4948311.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            12315..12599
                     /locus_tag="IXT46_002419"
     CDS             12315..12599
                     /locus_tag="IXT46_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAQ4948312.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            12650..14275
                     /gene="groL"
                     /locus_tag="IXT46_002420"
     CDS             12650..14275
                     /gene="groL"
                     /locus_tag="IXT46_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAQ4948313.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4937 a         2452 c         3044 g         4135 t
ORIGIN      
        1 taaatctctt tctgaataca cgggtatatt cgatgaagat atttatgaag cttttccact
       61 tgagaggttc cctatagaat acgaatacgt tcataaagta aattttaatg aaattcaaaa
      121 aaaatataaa agctattttc ctaacttatt tgacaatgat caattaacat tgagaattaa
      181 ggataaaaag aatagtcatt cattaaacat tgatatagtt tatagtgcgt taaattttat
      241 gaaaaatact tggcaagatt tgaatagtag atatacggat tggggtcctg aaaaaaaatt
      301 attgatgacc gcaccctcaa aaggatcatt aaaacttgaa tttgaattag caaatgatga
      361 acaaacagct ttgttttctg atgaagcatc tttctcagaa ttaatcgatt ttgtagataa
      421 cttaatgtat acaccgatgt atgatgatga agaattaata aatgaaagaa aaattattga
      481 agagaccgtc aaactatatg aagttattga aaaaaatgat ttatcaattg attttatttc
      541 taatgatgtt aagttaagta atataagtaa atctagtaat attaaaaaaa atctcgatgt
      601 tttaaaagct cgcgtaaatg ataaaataat agaaaatagt actttaaccg aagatattga
      661 agtaagtggt gaagtattag cagcaaataa gagtaaaaat tattttaaga taaaatcatt
      721 ggctttagga gatattggtg gtgtttttga aaaagaatta tttaaaaaaa taaaaaattc
      781 tgaaaaacaa attactgtat ctaagaatat aacagcttgt attactaagc aacaaattac
      841 taatattgat acaaatgaaa taaaaactaa gtacgttatg acatcatttg atcaataaat
      901 gcaagacttc aaccaatcac ccttggttga ggtctttttt cattttttct gaaaaatcta
      961 agcaaataat agactaaaaa agaaccatgt gagataataa acatagaaaa aagcttcaga
     1021 tactccctca ccctagagtc tttccccaaa aagataagta tctgaagctt ttttcttttt
     1081 atgacttgga aataatagca taaaataata tattttacaa agaataagta caatctagtt
     1141 ttttgctatt aaatgtgtaa taattaatgt gccatcacaa caaagaatga aacccattat
     1201 tatctagtct atgtccattc tttttgtttg cagtagttgt gatagctttc cgtaccttta
     1261 gctcagttgg ttagagcaga cggctcataa ccgtccggtc gtaggctcga gccctacagg
     1321 gtacatatat accaaaagca ctcatcaatt taattggttg agtgcttttt tattgttatt
     1381 aaaaattaaa aaactaaaat acatacccga atttcatacc cgaaaaataa aaaatgccac
     1441 cacgtacact cttttcgaaa ctacctaagt agccaagaat gtactggtga cgtgggtttg
     1501 gcacccaatg ggccgtgagg ggctcgaacc cgcgacccgc tgattaagag tcagctgctc
     1561 taccaactga gctaacggcc cgtacaaaaa gtacttaata atagtagcac taagaatttt
     1621 aaaatgcaag actacattta aagaaaatca gaaaaatctt tacttcctta taggaaatca
     1681 ttcatagatt attcacattt gctcgctatt atataagcat accaacaaac aaagttcttg
     1741 caagagaaca aacctaacac ttttttcatt ttttactcct ttcccgccgt ctccccggcg
     1801 ggtctcctgt tcttaacgat aaaagacaag aaggcttagc cttcttgttt tttgttttca
     1861 tggaatcccg ctaatcaaat cacctagtta aagcaactag attgaatgtt tatcataagt
     1921 ctgatatcat gtttatgaaa tgaaaaaagg agcggttatg atggaaaaaa tgcgtcagca
     1981 attaatggag tgggggaagg aactagaaac attccgtctg cctcactggg aagaactccc
     2041 tgacttagaa ctttatatgg accaagtcag aacgttagtt gatcgttatc tttcacctgt
     2101 gatacaagga gaaaagcatc cattgcttac ctcttctatg gtaaacaatt acgttaaact
     2161 aggtttgata ccagcaccag ttaaaaaaag atataacaaa gaacacgtag catttttact
     2221 tgcaatcact acgttgaaac aagtattgac tattcctgaa atcaaagaag ggatattgtt
     2281 ccaaggaaaa acagtaggaa ttcgtgaagc ctataatcta ttttgcgatg aacaagaagc
     2341 agctgtgtgg atggtcagcc aattagcaca aggtaaatct catccgcaaa aattcgacca
     2401 ggcaacccct gtagaatata ttgctgtaag agcggcaact ttatcgtttg caatgaaact
     2461 tcttgcggaa aaaacgattg ttctagaaac cgaatattta aaagaggaga aaacaaatga
     2521 aaaacaataa aatcgcaatt ttagtagatt caggtacgga tgtgccagaa gaattgataa
     2581 aaaaatacga gatgtatatg atcccattga aaattattta taaagatcag gtatatacag
     2641 ataaaattga cattacccct gaagagatct atcaacgttt gccagaggaa atccctggta
     2701 catctttgcc ggatggtgag tcgatcacag aaatctttga gcaaatcaaa aaagacggtt
     2761 atgaaaaggt acttgcggta acaatttcca gtggattgag cgggacatat aatgtggttc
     2821 gtttaattgc acaacagcaa gaagaattgg aagcatatgt actagatacg aaaaatattg
     2881 gtattggtgc aggtttttct gcgatccaag cagcaaaatg gctggaagaa ggagtagaat
     2941 gggatcaact gatcagtaat ctgaatgagt tagtcgaaag aacaaaagtt ttctttaatg
     3001 ttgcgacatt ggaatatctt caaaaaggtg gacggatcgg tttagttgct tctattgtag
     3061 gaaccgcttt aaagcttaac ccaatcatct catgtaatga agaagggatt tattacacag
     3121 taggaaaagc taggggacgt aaaaaaagtt tggataaaac ggttgcttac gtcaaagaaa
     3181 aaatcggtaa tgcaaaggtc ttcaacttag ctgttgccca tggggatgcg aaagaagaag
     3241 caattgaaat ggaagcgaga cttaaaagag agttcccaca agcaaaccaa atctactttg
     3301 gccagatttc tccggcatta gtagtccaca ctggtccggg attattgggt gtcggtgtac
     3361 aagttttaga aggataaatc aaaaaaagga aacactgagg tgaaaatcag tgttttcctt
     3421 ttttattgaa gttagaacaa aaaataataa agtattttgc actttcattt taattttctc
     3481 ttttgtttta taggcaaaga tgaaacaaaa gcagaaatac ggtataatga gaaggtatga
     3541 caataatata taagaggtgg ctctttatga aaaaagtttt agttgtcgat gatgagaagc
     3601 cgatttcgga tatcgtcaaa ttcaatttag ccaaagaagg ctatgatgtt tatactgcat
     3661 atgatgggga agaagccttg gaaaaagttg ctgaggtaga acctgatttg attttacttg
     3721 atttgatgct acctaaaatg gacggcttag aagttgctcg tgaggtacgc aaaacttatg
     3781 atatgccgat cattatggta acagccaaag attctgaaat tgataaagtc ctaggcttag
     3841 agttaggcgc cgatgattac gtgaccaagc cattttccaa ccgagaatta gttgcacgtg
     3901 tcaaagcaaa tcttcgtcgc ggtgccacgg ctgcgaagga accagaagag gcagcacctg
     3961 cggaattgac gattggtgat ttgacgatcc atccagaagc ttacatggtg acgaaacgag
     4021 gagaaacaat cgagttaaca catcgtgaat tcgaactact cttttacttg gcgaagcacc
     4081 ttggacaagt gatgacaaga gaacatttat tacaaacggt ttggggttat gattattttg
     4141 gagatgtacg aacagtggat gtaactgtac gtcgtttgcg tgaaaagatc gaagataatc
     4201 caagccatcc aaattattta gtgacacgtc gtggtgtcgg ttactatttg cgtaacccag
     4261 aacaggagta attggatgaa aagaaaagtc cgcttttttc gatcagtcaa ttttaagatc
     4321 gctattacct ttattctgat tttattgatc tcgatcgaaa ttattggtgc ctactttata
     4381 cgtggtttag aacgttccac gatcaataca tttattaaag atatgaatca aacggtggaa
     4441 tcattagcaa caacaatcag cccggaattg aatcgaaaag ataatgcaga tgatgaagag
     4501 gtaaatgcga atatcaaaag atttattgaa aacagtgcga ctagcgatat catcgaaata
     4561 cgggtcgttg acgaaaaagg gatcatccga ggaacaaccg atgtcaatga acaaagcgct
     4621 gtgggaaaga aaaatgatta tgttgatatc aatgatttca cgactaaacg ttatgttgct
     4681 ttagataacg acgataaacg ggtgaatatc aatgttcaac cgatcctgtc cccgaccggc
     4741 gatgccgtta tcggggctct ttacgtcaaa agtaatatcg aacaaaaata ttcggaaatc
     4801 aataacacag cagtcatttt ctttactgcc tcactaattg cggcatttat ttcaatgatc
     4861 gtatctgttt tagttgctcg ttcgattaca cagccgatcg gtgaaatgag agaacaagcc
     4921 attcgaatcg ctagaggaga ctacagtcgg aaagtcaaag tgcatggaca agatgaactt
     4981 ggacagctgg ctgatacctt caatcagtta gctgaacgta ttgaagaagc tcaagataca
     5041 atggaagctg aacgcaatcg tttggatagc gtgctatccc atatgacaga cggcgtcatt
     5101 gcgacagatc gcaggggtaa agtcattacg atcaatgata tggctgtttc cttgctagat
     5161 atcaaaaacg aggaagcaat cggacaatcg attttgacac ttttagatat cgaagaagaa
     5221 tatacgttgc ggaaattatt agaagatcca aacgaaatgg tacttgaccg ttcaaccagt
     5281 acattggaaa gtgatcagat gatcttgcga gtagactttt ctatgatccg tcgcgaatca
     5341 ggttttatca gcggattagt agctgtcttg catgatgtga cagaacaaga aaaaacagaa
     5401 cgggaacgtc gtgaattcgt ctctaatgtt tcccatgaac ttcgtacacc gttgacaagt
     5461 atgcgtagtt atatcgaagc attgagcgaa ggtgcgtgga aagacgagga agtagcacca
     5521 aattttttga aggtaacgct agatgaaaca gaccgaatga ttcgaatgat caatgacctc
     5581 ttaaatctat ctcgcatgga tacaggtaat acccagcttc aattagaata tgtcaatttc
     5641 aacgagttag tgaattttgt tcttgaccgg tttgatatga tggtgggaaa tcaggaaaaa
     5701 aattataaga tccgtcgtga atttacgcaa agagatcttt gggtcgaagt agatacagat
     5761 aaaatcatcc aagtagtcga taatatcatg aataacgcga tcaagtattc accagatggg
     5821 ggaacgatta cttgtcgctt attagaaacg cataataacg tgattttaag tatcaccgat
     5881 caaggattgg ggattcctaa aaaagatctg aaccgagtgt tcgagcggtt ctatcgagta
     5941 gataaagcac gtgcaagagc acaaggtggg acaggacttg gattagctat ttctagagaa
     6001 gtgattaagg cgcatcgagg cgctatttgg gcagagagca aggaaggaaa agggtcgact
     6061 ttttatatct cgctgccata tgaaccttat gaggaggaat ggtgggaatg agaatctctg
     6121 aaaaagtcgt tcgtatagga ctcattttga tggttgcgtt aagcatatac ttctcttatg
     6181 caatctggct gagcccagca ggaaaaagtt caatcaacgt agatgagaca aacactcaaa
     6241 tgatcgagtc tcaaagcaat cgaaaaactt ccgaagtctt tcttccgctt catgttacat
     6301 ggcaccattc gggaatgatc caagaaacca acagtgaaaa tctcgtgtac cgattgcaat
     6361 tgatcatcga taaagcaaga tttggaaagc tttctgaagt agtttcagga gacaaatcac
     6421 agtttgaaca ggtgaaaaat ctgaactctg gttttgagtt ggcctataat gcgccttttt
     6481 tgctaagaga atacaaggaa gcatttgatt tagatttaga tgtgtcgaac ttggcaaaag
     6541 aaagcgaaaa tatgtatttt actagaatac aattcgatca aggaaataaa aaaatccgat
     6601 ttttgaatta ttcgaaccat ctcgtatatg aagcaaatat ttcgttgaat tggacagata
     6661 tcaataaaga attaacagca aaagacacaa aatggacaga aatgacaaca gaaccatcga
     6721 cgatcgacac gcaatatgct acgaaacatt cgatcaaact gaaaaagtat agttatatcc
     6781 tgtcacagca accctataca ctttttagaa atgctttttt ccagaaacca gatagcgtga
     6841 aaaataatga tgaaagcaat gaattgattt tttacggtgg gaatgaaaca atgtctatcc
     6901 attcggaaac gcaagtagtt gattttcgtg gagagctgcc agagaaaaaa gaaaatgcta
     6961 gtgtattttc tgaaagtttc ccctatatta gcaaattagg cagttcttta gggaacctca
     7021 gatattttga ccgcagtgac aatacgatcg attatcggat attcgtggaa ggcttcccgg
     7081 tttttgggac agacagcaga ggacagattg gtgtggaagt tggcggtgaa acgaatggtt
     7141 ctgtgcaagt gaatatccaa accagtttga atacgattca agtgccgata ccttcagacg
     7201 aagaagtaga acttgcaagt acgaatgaaa tcatccagca gttaaaagct aagggagcag
     7261 atagcaacaa gattggttca gtgatcgttg gctatacatg gcaaaatgtc aaagaaacga
     7321 atcgtgtcgt tgatctctta cctgaatggt atgtgaaata taaagataac tggtattcag
     7381 ctaacgacct tctggaaaaa ttacctggat tggaggcgaa ttaattggat ttcaaaaaaa
     7441 tcgaatggat atttttcgtc gcttttttag ggttgaatgt gtttttattc agcagttatc
     7501 atgacgcggt ataccaagaa aacaatgtca ttcgctctaa tcagactgaa tcaatccaac
     7561 aacgtctggc tagcgacgat atcacttaca cggggaagat ttcgtctgag aacaagcaag
     7621 gctattatct tagcgcggag cagaccaatc ttagcacttc attagcgaat tatcgcaagg
     7681 ctggtaaaag cggcttgctg gcaagtggtg tgtttttaga cggtgatgtt ttgacgaaat
     7741 ctttatccag ttcagatgct gaaaagaacg tgatcgatcc agataaaatt agtagttcct
     7801 tggaagattt tttatctaac aaagacaata ttttattcgg taatgattat gtgtacacga
     7861 aaaacttttc tcatttagaa gaagaaccac tagaaatcca agcaagccaa gagtatgaag
     7921 gcatcccatt caatgatgat acagcaaaaa tcgttctttc tttagaaaaa aacgataatg
     7981 attatagcat cacgaaatac atgcagacgc atttatctga tatcgagcag ctgcgcgaaa
     8041 agacggaact gtatacggaa gaggaagcaa tcaatacatt gtacatcaat aacaaaatac
     8101 caagaggatc aaaaatttta tggcgtcagc tagcttattc ctgtattctg aaagtccggg
     8161 aaaaaaatgt gtatgttcct gtttggcatg tagcgatcga aacaagcgat aaagtggtcc
     8221 aaattgagag cgtcaacgct ttcagcaata cgatcgtgac aaacaatact gtaccaaaag
     8281 tggaagatca ataaaaaagc gagtataatg aaaaaagttt acaaagtaag aagggaagta
     8341 ggagtcaaat ggctgaagaa aaaccagctt ttaaaatcag tatcctagca agtggaagtt
     8401 cgggtaattc actttatatc gaaagtgaaa aaaaacggct tttggtcgat gcaggactta
     8461 gcggtaaaaa aatcacttcc ttgatggctc aaattgatcg gacaccggac caattagatg
     8521 gaatacttgt gacgcatgaa catcgagatc atatacatgg cgtgggtgtc ttggctcgta
     8581 agtatcattt ggatgttttt gccaatcagc agacttggga agcgatggaa ccactgattg
     8641 gaaatgtacc agtggaacaa aaacatctat ttgagatggg gaaagtcaga acattcggcg
     8701 atatcgatat tgagagtttc ggcgtctccc atgacgcagc ggctccgcaa ttttatcgtt
     8761 tccataaaga aaatcggtca ttcgtcatgt tgacggacac cggatattgc agtgattata
     8821 tgcgaggtgt cattgaaaat gccgatggtt atttgatgga aagtaatcat gatcttgaga
     8881 tgttacgcat gggaccttat ccgtggaatt taaaacagcg tattttagga gatagaggac
     8941 atctttccaa cgaagacggt gcacttgtca tgactgatgt gatcggtaat cggaccaaac
     9001 gaatctatct tggccatctt agcaaggaaa acaatatgaa agaacttgct catttaacaa
     9061 tggaaaatgt tttgaaagaa aaagattttg gcgttggaca tgattttgaa atctatgata
     9121 cagatccaga tgaagcaact gagctatttt cgatttaaac agttcaatca ataaaaatat
     9181 aaaaagcaga agataaaatc aatcagggtt ggttttatct tctattttta tttttttagc
     9241 atattaaaaa aataaccgta ttatcgactg actacactga tgtgctgctt ttcatgtttc
     9301 tcatccagta tctcatctac taatgcaatc gcgtaatctg ccatgctgat cgtactgtcg
     9361 ccagcagcgt ttctttgtaa ataatcatca cttaacaaat aagtacctgt acgtttgcca
     9421 tgtggatcaa ataaagaagc tggactgata taagtccaat gtagattttt agattgtttc
     9481 aattttaaca atccttcgta catattgaaa gctgttggat agaagggtgc atttttaggt
     9541 acttggtcaa tcatacgagt cgtcttttct gtatctaaga ataacgaaga ggcaccccca
     9601 acgacaatta agcgtgtatc ggttccttca agcatctcaa tcaaatggga caaagaagtt
     9661 tgatgcattt cttcttttcc tttgggagcg ttgaaagcat caacgacaac atcaaaagat
     9721 gcaagatcag tagttgtcaa ctcaaataaa tccttttgta taaacggaac atctgatggc
     9781 aatttttctg gatgacgcac gattgccgtc acgtctaaat ctctggacaa tgcttcgtct
     9841 aaaataaatg aacctgcatg gccagtagct ccaatgagtg caattttcat aaaaaacctc
     9901 cttttttatt cctgtccatt gtaagcagtt gctgaatatt cgtcaaagaa tccgattttt
     9961 gaaaagctca gtgcgcattc ctttcatggt tcgtgatcat tgggtatagt taaattaaga
    10021 aaactgattg ataaaaatag aagttgaagg agataagaaa tgaaagagtg gttagatcgt
    10081 gcctttttac caatgataac atctgttgtg aatcttagac ccttaactgc tttgcgtaat
    10141 ggaatgactt acacgatccc aataattatt gttggctcgc tgtttttctt atttgctcat
    10201 tttcctgtgg attacatcgc tcagtggata gacaaaacag gattttctat gtattttaca
    10261 caagtatacc aggctacatt tgatgtgata gccttttgga tcgtttttgc cattgcatac
    10321 gcttatgcaa aagaagaaga catcgatcgc ttaccagtcg gcataacagc cttgtctgct
    10381 tatctactgc ttattcagcc actaaatact cagatagata ctgtctggac aggtgctgaa
    10441 gggatactag gagcagttac aactgggctc atcatcggat ggggctatgc acgtttagta
    10501 agacttgcga aagggtggaa gcaaagagag aagatacctg aaaatgtttg gcagtctttt
    10561 acttcattga ttccaatcat tgttatagtc acttttacgc ttatcggttc agcggttttt
    10621 caacagttgt tcagaatgac tgttgttcaa ggagtatgga catatgtcca gcttcccatt
    10681 caatcgttca tagacacgtt gtttggtgtg cttttattag gtttttttgt tccgttttta
    10741 tggttatttg gtcttcatgg atctgcgatg gtcaatgggt tggttagtcc cgtcttgcaa
    10801 gcgaattcat tagcaaatgc agaaatctta gcctcaggac aagagttgac ggtggcaaat
    10861 ggcggacata tcgttactca gcaatttctc gatcagttca tgacggttac gggtgctgga
    10921 ttgacgttag gggctgtatt ttttatgacg gtttttgcga aatcgaagaa atacagagaa
    10981 ttaggaaatc ttgctctttt accagccttt ttcaacatca atgaatcaat tattttttcc
    11041 acaccgatcg tgatgaaccc gatgatggct gttcctttta ttttcgcacc ggtcgtttca
    11101 ggattgatta cctattccgc tttatatttt ggattcgttc ctttatttac agcagtccaa
    11161 gtcccttgga caacaccgcc gatcctctcg ggtttcttag taggcggagt gcctgcagcg
    11221 attttacaag gtatcgtgtt gtcaattagt tttttcattt atttcccatt tttgaaaaaa
    11281 atagattctg caaactgcaa aaaggaaaga cagacaaaaa atgatggagc agcagaaaag
    11341 atgaacgact aaaaaacaaa aatactcctg tcgctttaga ttgggaaaat caccaatcta
    11401 ggatgacagg agtatttata gtcatgttta tactagccct ttttggacag ctaattgaac
    11461 aagaacaact aatgtgttca ttcctacgtg tgtgatcatc gatgtccaga tccgaccagt
    11521 tgctttgtac tctaggctga agaagaaacc taggaaaaag tagattagca gatgaccatc
    11581 attatgagca aacgcaaaca gcaaagagct gatcactgct ccgacccaaa aatttgaata
    11641 tcgactgatg atccccagta tactgcggcg gaatacgaac tcttccatga tgggtccagc
    11701 aacagttgtc gccaaaataa aagcgggtgc ttccatgatc atctggatga tattttgtgt
    11761 attctcggaa ggggttgctt tgccaaacaa tacagattct aacatgacag cgatgctttg
    11821 cagaatcaat gcgacaaaga ttccaaccaa tccataaata acaatctttg gagcagaagc
    11881 tttttttacc gctgattcga tcgctaaggg ttcacgttgc ttaaaataaa aaatagctag
    11941 gacaacggcg cctagtatat acatgactgc agttgctgtg atcaattcag acgtagattt
    12001 tacaagtcct atcgaagcta ggatcaaggg tgagataaaa attagaccat agcaaaaaat
    12061 gctgaggaag ctatattttt ttaaagacat gtaattcctc cttttaaggg ataacaagca
    12121 tgcaaggcaa gcttatatcg attgatttca attatatcat aatttcaata agcagctgtc
    12181 agaataaaat ttcttttctt tgatttaaaa gcttgcaaaa aagagggaga atgagtatta
    12241 ttaaaaatgt aggttagcac tcgaaggtta agagtgctaa cagattaaaa aaagagttat
    12301 cggagggatt tatcgtgtta aaaccattag gtgatcgcgt cattatcgaa gtcgcaaaag
    12361 aagaagaaaa aactgtcgga ggaatcgttt tagcttctgc tgctaaagag aaaccccaaa
    12421 ctgggacagt tgttgcagtc ggtgaaggcc gtttgttaga aaacggtgaa aaagttcctg
    12481 ccgctgtaaa agcaggcgac caagttatgt tcgaaaaata cgccggtaca gaagtaaaat
    12541 acgaaggaaa agaatatctg atcgtcgcag gaaaagatat catggcgatt gttgagtaaa
    12601 tttggaagat aaaaaaataa tcaaaaataa tcaatgaggt gaatcaatca tggcaaaaga
    12661 attgaaattt gcagaagacg cacgcgcagc tatgttacgc ggggtagata aattagcaga
    12721 tacagtgaaa gtaacattag gacctaaagg ccgaaatgtc gtactagaaa aatcttacgg
    12781 ctctccattg atcacaaatg atggtgtgac gatcgcaaaa gaaatcgaat tagaagatca
    12841 ttttgaaaac atgggtgcaa aacttgtatc agaagtagca tcaaaaacaa atgatattgc
    12901 aggagacggt acaacgacag caactgttct gacacaagca atcgttcgcg aaggtttaaa
    12961 aaacgtaact gcaggtgcta atcctctagg cattcgtcgc gggatcgaat tggcaacaaa
    13021 agcagcagtc gaagaattgc ataatatctc aactgttgtt gattcaaaag aagccattgc
    13081 acaagtagca gctgtttctt cgggttctga taaagttgga catttgattg ctgatgcaat
    13141 ggaaaaagtt ggaaacgacg gtgtcatcac aatcgaagaa tcaaaaggga tcgaaacaga
    13201 actagatgtt gtagaaggta tgcagtttga tcgtggttac ttatcacaat atatggtaac
    13261 agataacgac aaaatggaag ctgttctaga aaacccatat atcttgatca cagacaaaaa
    13321 aatctctaac atccaagata ttctgccatt gttagaacaa atcttgcaac aatcacgtcc
    13381 attgttgatt attgctgacg atgtagatgg tgaagcattg ccaactcttg tattgaacaa
    13441 aatccgtgga acattcaacg tagtagctgt aaaagctcct ggtttcggcg atcgtcgtaa
    13501 agcaatgctt gaagatatcg ctattttgac aggtggtaca gtaattactg acgatctagg
    13561 tttagaattg aaagatgcaa caatcgaaaa cttaggaaat gcttctaaag ttgttgtaga
    13621 taaagacaat acaacgatcg tagaaggttc tggagaaaaa gaagcaatcg aagctcgtgt
    13681 gcaattgatc aaaaaccaaa ttgctgaaac aacttctgat tttgaccgcg aaaaattaca
    13741 agaacgctta gctaaattag caggtggtgt agctgttgtt aaagttggtg cagctactga
    13801 aacagaattg aaagaattaa aattacgcat tgaagatgca ttgaatgcta cacgtgccgc
    13861 agtagaagaa ggaatggtct caggtggtgg tacagctcta gtgaacgtta tcagcaaagt
    13921 ttctgctgta gaagcagaag gagacgtggc aacaggtatc aagatcgttg ttcgtgcttt
    13981 agaagaacca attcgtcaaa tcgctgaaaa cgctggttat gaaggatcag tgattgttga
    14041 taaattgaag aacgtggaac taggcactgg tttcaatgct gctactggag aatgggtaaa
    14101 catggttgaa gcaggtatcg tagacccaac taaagtaaca cgttctgcct tgcaaaatgc
    14161 cgcttccgtt tctgccttgt tattaacgac agaagcagtc gttgcagata aaccagaacc
    14221 agcagcgcca gcagctcctg caatggatcc atcaatgatg ggcggtatga tgtaagaaaa
    14281 agcaacttgc ttatctacaa ctgatcatta gtgaaagaca gataaaaaga ggctggaaca
    14341 gaagcgttta actccaagaa ataagaagaa attcacggaa attgcttttc aaatttttgt
    14401 gaatttcagc ttatttccga aggagttgct tctgcttccg ctgtttatac gtgtttagag
    14461 cgtgagacaa aagtgttctt tacttttgtc tcacgctctt ttttgtgtgt aattataatg
    14521 aaaatagtta tttttaatag ttataatatt ttatctatta aaagtaaa
//
LOCUS       DACGMI010000069        14411 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.071, whole genome shotgun sequence.
ACCESSION   DACGMI010000069 DACGMI010000000
VERSION     DACGMI010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.071"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..916
                     /locus_tag="IXT46_002421"
     CDS             <1..916
                     /locus_tag="IXT46_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAQ4948314.1"
                     /translation="VKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQGAHHQFI
                     ASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFSDVQARGY
                     YPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENWEGVQGNL
                     ITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDKVEEDGTV
                     QDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGYIYVDQDD
                     EGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            1500..1934
                     /locus_tag="IXT46_002422"
     CDS             1500..1934
                     /locus_tag="IXT46_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4948315.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            2035..3126
                     /locus_tag="IXT46_002423"
     CDS             2035..3126
                     /locus_tag="IXT46_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAQ4948316.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            3156..3833
                     /locus_tag="IXT46_002424"
     CDS             3156..3833
                     /locus_tag="IXT46_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAQ4948317.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            4165..5460
                     /locus_tag="IXT46_002425"
     CDS             4165..5460
                     /locus_tag="IXT46_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4948318.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            5450..6910
                     /locus_tag="IXT46_002426"
     CDS             5450..6910
                     /locus_tag="IXT46_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4948319.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            7046..8542
                     /gene="glpK"
                     /locus_tag="IXT46_002427"
     CDS             7046..8542
                     /gene="glpK"
                     /locus_tag="IXT46_002427"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAQ4948320.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            8556..10379
                     /gene="glpO"
                     /locus_tag="IXT46_002428"
     CDS             8556..10379
                     /gene="glpO"
                     /locus_tag="IXT46_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAQ4948321.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            10380..11096
                     /locus_tag="IXT46_002429"
     CDS             10380..11096
                     /locus_tag="IXT46_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAQ4948322.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            11402..13330
                     /locus_tag="IXT46_002430"
     CDS             11402..13330
                     /locus_tag="IXT46_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAQ4948323.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            13456..14010
                     /locus_tag="IXT46_002431"
     CDS             13456..14010
                     /locus_tag="IXT46_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAQ4948324.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
BASE COUNT         4824 a         2424 c         3209 g         3954 t
ORIGIN      
        1 agtaaaatat tggatgactt tcaatgagat caactgtgta aaacatcacc cttttgttag
       61 cgtaggagta attgaagaaa accatcccca tttggaacaa gcgaaatacc aaggtgcaca
      121 ccatcagttt atagcaagtg ctttagctac aaaagcttgt catgaaatta tcaaaggttc
      181 acaagtcggt tgtatgatca gctatcagct tcttgttccg tattcttgtg atccggatga
      241 tattcaaaaa acaattgagc agcaaagaac ttctttgttc tttagtgatg ttcaagcaag
      301 aggatattat ccagcgtata cgcaacgaat gtttgaagaa aaaggtgtca acttaaaaat
      361 agaagtaggt gatgaagaaa tcttagcagc ctaccctgtt gattttgttt cttttagcta
      421 ctacatgtct agtgcagtca gtgctcatcc agaaaattgg gaaggggtcc aaggaaactt
      481 aataactgga ggaattaaaa atccgtatct tccatcaagt gaatggggct ggcagattga
      541 tcctaagggt ttgagaattg ctttgaatca attatatgat aggtatcaaa aaccactgtt
      601 catagctgaa aacggactcg gagctataga caaagtagaa gaagatggaa ccgttcaaga
      661 cgattaccgc attgactatt tgaaacagca tattgagcag atgaaggaag ctatcaaaga
      721 tggagtagat ttatttggtt atacgtcgtg gggctgcatt gatatcgtca gcgcttctac
      781 ttcacaaatg tcaaaacgtt atggatatat ctatgttgat caagatgacg aagggaatgg
      841 cacaaagaaa cggttaaaga aaaaatcatt tgattggtac agacaagtca tccaatcaaa
      901 tggcgaaatc ctataataaa aggaaataag ggactgtgac aaaagtcttg tcacagcccc
      961 ttctttacga ataaacagta ttctcctgcc aactcctcga tcacaagtca ccatagtcat
     1021 aaaacatgag aagctgtttt ttgaaattgc tccttgtgac tcggagttca acggcaggct
     1081 cacgacctct caataaacgg tgtacaatca gctgaccatc ggcattagct caaaaaacga
     1141 caaaatatga ggaactattt ttgtttggct gttcttatta cttgatgcag gacggctttt
     1201 tcacaacctc tgatataaac ggtgttcaaa agccagtttt tcggtattaa gccaaattta
     1261 tgcaaaaatg tggaaagcca ttttcacaaa atttttcttc atactcaaaa ctaaacgact
     1321 ttttcacaac ctctgattca cggtgttcca gaaggagttt tgtcgaaaac aagccgaaat
     1381 tctttgaaga tggctacttc tttttttcaa atctagacag aggaggcgga cattattccg
     1441 tgttttttga caaaaaataa aaatcatact atgatatgta cgccaatgga ggggatgaaa
     1501 tggaaaagcc aattgaaaaa gcgttagatg aatgtctttt ctttagcgtg aaaaagctag
     1561 atcgcatgtt gaataaatta gctgatgaag cgtttagaag gacaggtctg gcaccaactt
     1621 atggttttat tttattgata ttaaaagaaa aagatggaat accacaaaaa gatattgcac
     1681 aaatgctcta ttccgcccca tcaacgattg ctcgttttgt tgaaaaatta gaatataaag
     1741 gatacgtcaa aacagttagc gaaggtcgct tgtcattagt ttatcttaca gaacaaggac
     1801 gccaatttgc taaggaagtc gatggtagct gggaagaact tcatcagtca tacaaagcag
     1861 ttttgggaaa tgaagcaagt aaagaattag cccagacaat gaatgatgca acagataagt
     1921 tacaaaaaaa ataaaatttt ttaagcaaat tagttgcatg tacaactaat cgagtggttt
     1981 aatgatagat gattctcgat aggttaatca gagcgaatta tgggaggaat gacaatgtca
     2041 caatttgatc aatcaattac tttaccttca ggagttcaat tgaagaaccg attgatgctg
     2101 tcgcctatga cgacacaact cagctttttc aatggagtga tcaccgaaga tgagatcact
     2161 tattataaac aacgttctaa aggtcttggt gctgttatta ctggtgctgc aaatgtccaa
     2221 gatatcggaa aaggctggcc aggtgaactc agcatcgctc atgatgaaat gattcctcga
     2281 ttaagtgagc tagcgaaagc aatccaagga gaaggcgcaa aagcgattat tcagattttc
     2341 cacggtggac gaatgacaag tcgagcaact ttatctggag aacagcctgt atctgcaagt
     2401 gcagttgcag caaaacgtcc tgatgcggaa acaccacgag caatgagtga agaagaaatc
     2461 gttgaaacaa tccaagcatt tggcaaagcc acacgtagag cgattgaatc aggatttgat
     2521 ggaatcgagt tgcatggagc aaatacgtat ttgatccaac aatttttctc tccgcattcg
     2581 aatagacgag aggatcaatg gggcggtagc ttggaaaatc gttatcgttt tattgaagaa
     2641 ttattaacaa cggttttctc agcggttgaa caatatgcta aaaaaccatt catcgtaggg
     2701 tatcgtttct caccagaaga atatgaaaca ccaggtatcc gttttgaaga cacgatctgg
     2761 cttcttgaac gattacgtga gtcaaaacta gattatctgc atgtttcatt aaatatgtat
     2821 gatcgaatag ctcgttctga taaatacaac gataaatcga ttcttgaagt ggtccataac
     2881 acgattcaag gaaagatccc tttagttggt gtcggtggga tccgcaatcg cgaagatgta
     2941 gagcaggtat tgaaatatgc agaacttgca gcaattggac agcaaatgat cgtcgatcct
     3001 gactgggcag agaaattatt ggaaaaccgt gaggatgaat ttgtaacgaa accttttgaa
     3061 gaagcatata aagagcttta tttgccaagc ccattatata atttcttgaa agcacgttat
     3121 caataacgca atttttatag aaagaggatg ggaaaatgaa agtattgatc gtattaacaa
     3181 atgtagaaaa gtacgaaaag atcgagcgtc ctacaggttt gtggttaagt gaactgactc
     3241 atttttatga tgtattagta aaaaatggga tcgatgcaga ttttgtcagt cctaaaggcg
     3301 gatatgtacc tttagaaccg caaagtgttt tgaatatgga tgaaatcgat tgggcctatt
     3361 atgaagatga agatttcaga aatcgggcct tgggaaatac cttacgtcct gatgatgtgg
     3421 atgcaaatga ttatgcagcg gtttattatg ctggtggcca cggaacaatg tgggattttc
     3481 cagaagcaat agatcttggg aaagtcgctt cacaaatcta tcgaaatgaa gggctggtct
     3541 cagctgtttg tcacggtgtt gtaggattgt tgccagttac agatgagtct ggaaaatcta
     3601 ttttagctgg acgtacagtg actgggttca gtaatgaaga agaggaagca aatggtacaa
     3661 cgaatgaagt accattctta gcagaagatg ctttgaaaga aaaaggagca aactatcagt
     3721 ctggagcagc tttttcagaa gtggttcaaa ttgatgggcg gcttcttaca gggcaaaatc
     3781 ctcaatctgc tcatcaatta ggcgaagcag ttgttgaagc attaaagaat taaaaataaa
     3841 tgatgtgtct attctaacta ttacattaca cacgctaaaa ctcgtctttt cgttcttttc
     3901 tgtttcctat ttggacagag gtacgtaaaa ggcgagtttt tttcttttat aagagtacat
     3961 tttttgaaac atctcttcag aaatgatact cttcaattag gtccactagt acattattga
     4021 gaagcagacc tagaacacgg tatgatggag agggttgatt ctgctgcatc gctatgtatc
     4081 ataaggttga aagcgagtta tgaatactgt gttttctgat tgagaagtta gcagtagaac
     4141 accttataag aaagaggaat gcagatgaac attgtaattg tcggcgggtc gtttgcaggg
     4201 attcatgcgg ctatttatct tcgccaattg atgccaacaa gtgaaatata tttgattgaa
     4261 aagcaatcga agttaggatg gattcccagc gggttcaatt tgatattaaa aggaaaggtt
     4321 accagtgaaa aacaactttc ttggatcacg aaagaagaac tgactgaccg ctatcgaatc
     4381 catgtttaca cagaaaagac agtaatagga ttgaaagaaa aaaaagtcgt tttagcagga
     4441 ggaaaaaaat tggattttga tcgtttgatt ctagcgactg gttcaaatca aaagtttcga
     4501 aatatttctg cagaatcaac gcttattcac ccagttaaaa agatacaaaa cgtaacggct
     4561 cttcagcaaa agatcatgaa tgcaaagaaa attgcaatta ttggtgcagg acaagcagga
     4621 atcgaaatag ctgaagggtt ggcatcaaga aaaaaacaaa tccatcttta cgaaagccga
     4681 aagtcaattc tttttcgtta tctagatcct gaaatgacag aaccgttagt aaaggaaatg
     4741 aaaaatcaag ggctttcact ttttttagaa gaacaagttg tgtctttgac cgaaaatgaa
     4801 accgctattg tagagacgga aaaaagaaag gagaactatg atcttgtttt gctggctaat
     4861 cattctcgcc ccgacaatca gatgtgggaa gaacaattaa cattgaatga tgatggaacg
     4921 atctgggtag atgactactt gcaaacgtct caaaaagacg tttatgcgat tggcgatgcg
     4981 atccaagtaa cttttcgtcc aacaaatgaa aaaatgtatg tttctctagt aaataacgct
     5041 gtccgtacag cacgaaatgt cagcaagaca attagtggct cacagacaaa ggatcaggga
     5101 acctatcgtc cagtcggcaa tcagtggttt ggctatttct taggaagcgt aggtttgaca
     5161 gaagaagaga gcatttttta tccccaaaaa attgaaacag gatacgtaga ctacaagctt
     5221 acagcaataa atcaaagcaa agttaaactc aaatttctat ttgattctga aaaaaagatt
     5281 cttggagcac agctccaaag caaaaaagag atgttccacc ttcttgacca actgacaatt
     5341 gcagtagaag aaggatggac gtttgaacag ttagaagaac atgagctatt tttccagcca
     5401 gaataccgtg tgccagatat ggtgtggtca aaggtggcga atactgccta tgaagattga
     5461 agcattatta gaaagaaaag agcagttaca gatcctgatt ttgcgaaacc ttgttctgca
     5521 agggggaaca gcctctatca atggtttgag agagcatgtc caactgtcaa aagcctcgtt
     5581 tgatcaatat ttggaagata ttgaattgat tggccgaatg atggaaaaaa aagtagaagt
     5641 acagcgaaat gagtatcagg cgctgcttgt gttggacgaa gatgtaagtt tggaaaaaat
     5701 tctattgttt ttattgcagg aaagcttgaa gtttaagatg ctcgtctatt tattagaaca
     5761 tcagcaagta tccatcgttc gattagcgac agcgtttaat atcagtgagt cttctgtttt
     5821 tcgaaagatc aaagaattga accagctctt agaggaattt ggattacaaa tcaaaaacgg
     5881 tcaattatac ggagaagagc tacagatacg atatttttat tatgaactat tccaatatat
     5941 cccggaagat cagcgaccgc tttttttgca aaatacacca gaaaaaagac cgttcattct
     6001 aggattggac cgtgtattag aaacaacgtt tacggcatca gcagaagcac agattgcttg
     6061 ctggctcggg attacgaaaa aaagactatt gaatgaaaaa agtacgtacg caactttgaa
     6121 agaaaagaaa ttactctatc agtcggaccg gctttatcaa gcaatcgatc caatcatcgt
     6181 gatgcatctt agtcgaacag cagcagaact gaatgtatac gaaacaatga tgttttacag
     6241 cttttttgtt tctttttcga tagtagacga agaaatattt tatcagtatg atttgacacg
     6301 gagcaaaaag ttaccaaccg ctgttttaga tacttacatt cgggaaacga tgttatggca
     6361 ttatcgtcct cgtcgtttga aaatcaaaga agaaaaggca gtaggctacc aaatttccca
     6421 gatcaacaat gaatggtttt tctttgttgg aaagatcgaa gtctatgagc gtgatcggct
     6481 tttggaacag cagcagaaaa tgctcgggca ttccttaaca cagttactgg cgaaattaca
     6541 ggaaacagcg gtgcagcaat tgccgaggaa aagagctgaa gatagtgagc ttagttacct
     6601 gatgatccag tatgccaatg ttcttttgat gatcgatttt tatattgcaa aaccagtagt
     6661 gattggaatc gatttagaaa gtctgccgat ttatcgtatt gcttttcaac aatatctgat
     6721 cagagaactg aggggaatcg gcggtattga gattggaagt tatgaagaag gtaaagaata
     6781 tgatttggtg atcacatttt gccagagaaa caaaaaacag tgtgaatatt atctgtcaga
     6841 atttgcgtca ccttacgaca ttattcgatt gaaaagaaga atagagacgc tgaaaaaaga
     6901 aaagaattga ttaaaaaata gcttcataat aaaaaactgt caaaaaaaga aaaaaagaat
     6961 aaaattttga cagtttcttt ttttaaaaca gtagtatgat aagagtagtt aaagaaagcg
     7021 tttgcatata atggagggaa tcacaatgac agaatcaacg tatatcatgg cgattgacca
     7081 aggtacaact agctcacgag caattatctt tgacaagaaa ggaagacaca tcggcagttc
     7141 tcaaaaagag ttcacgcaat atttcccgca agaaagttgg gtggaacatg atgcaaatga
     7201 aatctggaat tctgtacagt cagttattgc cggagcgttc atcgaatcag ggatcaaacc
     7261 aaatcagatt gctgggattg gcataacgaa ccagcgtgaa acaacagtaa tatgggaaaa
     7321 agatacagga cgtccaatct atcatgcagt tgtttggcaa tccagacagt cagctggaat
     7381 tgcagataac ttaaaaaatg aaggctatca agaatttttc cacgaaaaaa cagggttagt
     7441 gatcgatgcc tatttctcag caacgaagat acgctggatt cttgatcatg tagaaggcgc
     7501 gcaagaacga gctgaaaaag gcgaattgat gtttggaacg atcgattctt ggttagtatg
     7561 gaaactgacc gatggacaag cacatgttac tgattactcg aatgccagtc ggacgatgtt
     7621 gttcaatatc catcagctag attgggatca ggagatttta gatttactaa atattcctcg
     7681 agtgatgtta ccaaaagtca cttctaactc agaagtttat ggttatacgc aaggttatca
     7741 tttttatgga agcgaagcac caatttcagg gatggcagga gaccagcaag ccgcattatt
     7801 cggacaaatg gcattcgaac caggcatggt caagaatact tatggtacag gttcatttat
     7861 tgtcatgaat accggtgaaa aaccgcaatt atccaaaaat aatttattga cgacaattgg
     7921 ttacggcata aatggaaagg tttactatgc tttagaagga agtatttttg tggctggttc
     7981 ttcgattcaa tggctgagag atggacttca aatgttgcaa aaagctagcg attcagaaga
     8041 cgcagcgaaa cgctctacaa gcgaagatga ggtttatgtt gttcctgcat tcgttgggct
     8101 aggtgctcct tattgggatc aggcagcacg aggggctatg tttggcttga cacgtggtac
     8161 gacaaaagaa gatatcatta aagctacttt acagtcgatt gcttatcaag tgagagatat
     8221 catcgatacg atgcaagatg acactggaat caagattcct gtattgaaag tagatggcgg
     8281 tgcagcaaac aatgaatatc tgatgcaatt ccaaacagat atcttgaatg taccgatcca
     8341 acgagcagaa aacttggaaa caacggcgct aggggcagca tttttagcag gattagctgt
     8401 cggttattgg aaagatacag acgagatccg cgaattttat gaagctggca agctatttga
     8461 agttcaaatg gaggaagagc gccgagaaaa actttacaac ggttggaaaa aagcagtaaa
     8521 agctacccaa gcatttgaat aaggaggaaa tccatatgtt ttcaaacaag acaagacaag
     8581 atagcattca aaaaatgcag caagaagaat tggatctgtt gatcatcggt ggcggaatca
     8641 ctggtgccgg tgtggcagtc cagtcagcag catcaggaat caaaacagga ttgatcgaaa
     8701 tgcaggattt tgcagaaggg acttcctctc gctcgaccaa acttgttcat ggcggtattc
     8761 gttatctgaa gacatttgat gtggaagtag tagctgacac agttggtgaa cgtgcagtcg
     8821 tacaaagtat tgccccacac atcccaaaac cagatccaat gcttttgcca atctatgagg
     8881 gcgaaggagc aacaaccttc aatatgttct cggtcaaagt agcaatggac ctttatgaca
     8941 aactggcaaa tgtgacagga accaaatatg agaattatac gctgacacca gaagaagtat
     9001 tggaaagaga accgtttttg aaaaaagaag ggctaaaagg cgcgggtgtc tatctagatt
     9061 tccgcaacaa tgatgcccgt ttagtgattg ataatatcaa aaaggctgcc gaagatgggg
     9121 cttatctagt aagtaaaatg aaagcggttg gctttttata tgatggcgat caaatcgttg
     9181 gcgtcaaagc tcgtgacctg ctgacagatg aagtgatcga aatcaaagca aaattagtga
     9241 tcaatacgag tggtccttgg gtagataaag tacgaaactt gaattttacg cgtccagtct
     9301 ctcctaaaat gcgtccaact aaagggatcc atttagttgt agatgcgaaa aaactgcctg
     9361 taccgcaacc cacatacttc gatacaggaa agcaagatgg gcggatggtt tttgctattc
     9421 caagagaaaa caagacttac tttggtacga cagatacgga ttaccaagga gattttacgg
     9481 atccgaaagt cacacaagaa gatgtagatt atctattgga tgtgatcaat catcgctatc
     9541 cagaagcaaa tatcacattg aatgatatcg aagcaagctg ggcaggactt cgtccactgt
     9601 tgattggtaa ttctggttct gattacaatg gtggagataa tggatcgatt tcagacaaga
     9661 gcttcaataa agttgtcgat acagtaagtg aatataagga aaacaaagtt tctcgtgctg
     9721 aagtagaaga cgtgttgaac catttggaaa acagccgtga tgaaaaagca ccttctacga
     9781 tttccagagg tagttcttta gaaagagaac cagatggttt gctgacttta tctggtggga
     9841 aaatcaccga ttaccgtaag atggcagaag gagctttgcg attgatacgc caattattaa
     9901 aagaagaata cggaatagag acgaaagaaa tcgactctaa aaaatatcag atttcaggtg
     9961 gaaacttcga tccaactaaa ttagaagaaa cagtgacaga attagcaaaa gaaggagtag
    10021 cagccggttt agaggaagaa gatgctactt atatcgctga tttttacggg actaatgccc
    10081 gacgtatctt tgaattagca aaagaaatgg caccttatcc tggtttgagt ctcgctgagt
    10141 cagctcggtt acgttatggt ttagaagaag aaatggtttt ggccccaggc gattatctca
    10201 ttcgtcgtac aaatcatctg ttgtttgaac gagatcagct tgatgagatc aagcaacctg
    10261 tgatcgatgc aattgctgga tattttgaat ggacagaaga ggagaaggcg caacagacta
    10321 aacgtttaga agcattgatt gcagaatcag atctgcggga actaaagggg gagaaataaa
    10381 tgaacagtga tatgactcaa atcatgggag agtttattgg gacactgatc ctagttttgc
    10441 ttggagatgg tgtgtgtgcg gctgtgaatt taaacaaaag taaagcacag gcttctggct
    10501 ggattgtcat cgcatttggt tggggactcg ctgtaacaat ggctgtctat atttctggat
    10561 tcatgggccc agctcatttg aatcctgcag tctctctagc tatggcgatg acaggggcaa
    10621 ttagttggaa tcttgtcgtt cctttcatca ttgcgcaagt tttaggagct tttgcagggg
    10681 ccattcttgt ttggctttct tatttgccac attggaatgc aacgaaagat gaaagcgcga
    10741 ttttaggaac gtttgcaaca ggtcctgcta tacggaatta tccagcaaat gtgatcacag
    10801 aattaattgg tacatttgta ttagttcttg ggttgctagc ttttggacaa aacgaatttg
    10861 cacctggaac gaacgtattc gctgtaggtg gattgatctt agccatcggt ctttcattag
    10921 gagggccaac aggatatgca atcaaccctg ctcgggactt tggtcctcga ttagcacatg
    10981 cggtattgcc aatagctaat aaaggaactt cagattgggc atattcatgg gtaccaatcg
    11041 caggtccaat gatcggagca attatcgcgg taggtgtcta ttcattaatg gtgtaaatct
    11101 ataaaacata ctaaagtttg acaaccaaaa tgtgtcttgc tatagttaag tggaaaataa
    11161 ataagaccta gaagaatggg gtatgttttg tgagtgtagc tggtatctaa tcagtaagtc
    11221 gaatagccaa taaacaaagt ttatttggtg tgcttatgaa acggtacctg tcaggaaaac
    11281 aatatctttg tattctaata aggataggac atgacttttt taagctgtgt tctatccttt
    11341 tatttatctc taggccctta tttattttgg gacaggtatc tcttcaagaa aaggagagaa
    11401 tatggacaac gaaatgatta gtcaattaca atttgatcgg atcaaaaagg aaatccaagc
    11461 aagagcaatt ggaaactata gcaaaaaacg aatcagcgat atgacggtct cgacaaacct
    11521 acaaactgtc ttggatcgtc aagaagaaac aagagaagca cgcttgatct tagaaagcag
    11581 tcagcatgtt ccatttatgg ggttgccgag gatcgatgca ctgacagaac aagtcaaaaa
    11641 agggttgatt ctgcagccaa ccgatttgat cgaatatgcg gattttctta gaagcagtcg
    11701 gatgatcaca aagttttttg ataagaatca ataccagaca cccttgttgt ttgcttatag
    11761 caaacatctt cctgatttga taaatgtaga agagttgatt gaccagaaaa taaaaaataa
    11821 taaagtcagt gacgacgcgt cacgtaattt gcgtaaagta cgcaaacaat tacaactaat
    11881 cgaaaaagaa atccagtcaa aattactgaa attcttgcgt catccgaaaa acaaagaaat
    11941 gatccaagaa gcaatgattg ttcaaaaagg cgaatactat acgattccta tcaaagccag
    12001 ctataaaaat aaaatagatg gaacgattat cgatgaatca aataaaagaa cgacggtttt
    12061 tattgaacca actgtgattt ctaaattgaa tgaacactat cagttgttaa aagctgaaga
    12121 aatcagtgaa gaatatcaag tcctggcggc attgactggt gctatcgcag aaaacgaaga
    12181 agtgatcgat ttattgatcg aaacgatcac ggtgttagat atcatctttg ctcgggcaaa
    12241 atttagccga gaaatcaatg gaagcacacc tagaatcaat aaatcggaac atatcattat
    12301 caagcaaggc agacatccat ttttacctga gcatgcggta ccattggatg ttgaaatcgg
    12361 taaagactat cgaggcttga ttatcaccgg agcaaatgcc ggaggcaaaa cagtcgtgtt
    12421 gaagacagtc ggtttattga ctttgatggc gatgttcggt atgcaagttc cggcaaaaga
    12481 agggacagag cttgctgtct ttgatgagat tttcgtcgat gtcggtgacc accaaaattt
    12541 agaaaatgcg ttgagtacat tttctggtca tatgcaaaac atcgctgcta ttttgaaaaa
    12601 gataaaaagg aatacgttgg tacttttaga tgagattggc agtggaacag agccaaatga
    12661 aggggctgca ctagcgatcg caatcatgga atctatgtat gagcaagggg cattgatcat
    12721 tgccacgacc cattatggag aaatcaagaa attcgccgga gatcatgaag attttgtgcc
    12781 ggctgctatg gctttcgatc gggaagcact tcgtcctaaa tatcagttgc gggttggaga
    12841 aacaggagaa agccaagctt tgtggattgc tcataaaatg gatatgtcga tgaaattgat
    12901 ccatcaagca gagcgttact tggcggaaaa agcctatcgg acacagaaaa aagaatttct
    12961 tcctaagaca gcagttacaa ataggaagga gaataaaaaa gaacgccagc tctttgcaaa
    13021 aggtgatcgg atatttgtca atgaatacca aaaagaagcg ttagtttatg aagatatagg
    13081 tgaagatacg attgatgtat atttagacaa aaaaataatc cacgtgcctc gtcagcgtgt
    13141 tcgtctggtg cgttcagcag aagatctgta cccgacaggt tacgatttag acagtctgtt
    13201 tatcgattat aaaacacgta aacggcagcg tgacctagag cgaggatcaa aaaaagctca
    13261 taaagtacta gtaaaagaaa tgcgcaaacg acaggaagaa agaagagtaa acgatgaaaa
    13321 cagcaagtga ttatctcaaa ttagctcata atatcagtgg ctgtaaagaa aaataaaaac
    13381 agtgaaatca ttggttttat tccccgtgta agctaaaata aaaagaaaag agtgctgagg
    13441 aggtagggcg ataaaatgaa attaagcaca gactggcgta aagaaataca aacgattccg
    13501 aatcttttat cgatattccg tatttttttg ctgccgattt atctttattt tgtgctgaga
    13561 cagtcatttt atatagcagg agcggtcatt gttgtctcag gtttgtctga ttatctagac
    13621 ggggtcattg ctcggagata taatcaggta acagacttag ggaaggtgct tgatccgttt
    13681 gcagataaat tgacacaact ttttctgatt ttgtctatgg catggtatcg accgtggctt
    13741 tggctgttgt ttggtctatt cttgataaaa gaaggcttta tgtttgtagc tggattaatc
    13801 gggctatcta aaaatatcaa attaagtgga gcgaagtggt atggcaaagt agcgactgct
    13861 gtcatctatg ttggcatgat ccttttgctg cttttcccag aattaccaac gctgtgggtg
    13921 agagtcattt ttgccgtcat cacttacggt cttttacaat cttttgtctt gtatgctgtc
    13981 gagtaccgaa agatgtttca aagaaaataa aaaaggggtg tgacctatgt cgcattcctt
    14041 tttttgataa atagactccc agtagctact tctcgataat aagccaacca aaccaaaaac
    14101 aggagaagtt gtttttgaaa ttatttcttg tgattcggag ttaaatggta ggctcacaac
    14161 ctcttggtaa acggtgttca atcagctgac cttcggtatt agctcaaaaa acggcaaaat
    14221 atgagcagct atttttccgt ttgtttctct aatactcagg tcaaaccgct gattttacaa
    14281 cctcttcctt aaacggtatt caaaagccag tttctcggta ttaagccaaa tttatgcaaa
    14341 aatgtagaaa tccattttca caaaattttt cttaatactc gaaactaagc gactttttca
    14401 caatctcttc c
//
LOCUS       DACGMI010000070        14350 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.072, whole genome shotgun sequence.
ACCESSION   DACGMI010000070 DACGMI010000000
VERSION     DACGMI010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.072"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(143..1345)
                     /locus_tag="IXT46_002432"
     CDS             complement(143..1345)
                     /locus_tag="IXT46_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4948325.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1348..1542)
                     /locus_tag="IXT46_002433"
     CDS             complement(1348..1542)
                     /locus_tag="IXT46_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAQ4948326.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1589..2437)
                     /locus_tag="IXT46_002434"
     CDS             complement(1589..2437)
                     /locus_tag="IXT46_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HAQ4948327.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2642..2992)
                     /locus_tag="IXT46_002435"
     CDS             complement(2642..2992)
                     /locus_tag="IXT46_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948328.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3587..4033
                     /locus_tag="IXT46_002436"
     CDS             3587..4033
                     /locus_tag="IXT46_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAQ4948329.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            4657..5649
                     /locus_tag="IXT46_002437"
     CDS             4657..5649
                     /locus_tag="IXT46_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4948330.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5665..6549
                     /locus_tag="IXT46_002438"
     CDS             5665..6549
                     /locus_tag="IXT46_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4948331.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6598..8205
                     /locus_tag="IXT46_002439"
     CDS             6598..8205
                     /locus_tag="IXT46_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4948332.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8206..9690
                     /locus_tag="IXT46_002440"
     CDS             8206..9690
                     /locus_tag="IXT46_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAQ4948333.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9867..10859
                     /locus_tag="IXT46_002441"
     CDS             9867..10859
                     /locus_tag="IXT46_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4948334.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10911..11780
                     /locus_tag="IXT46_002442"
     CDS             10911..11780
                     /locus_tag="IXT46_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4948335.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12200..13765)
                     /gene="guaA"
                     /locus_tag="IXT46_002443"
     CDS             complement(12200..13765)
                     /gene="guaA"
                     /locus_tag="IXT46_002443"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAQ4948336.1"
                     /translation="MSSPTRFDEEPKIIVLDYGSQYNQLITRRIREFGVFSELMSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGK
                     VKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCP
                     IASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGK
                     FGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(13820..>14350)
                     /locus_tag="IXT46_002444"
     CDS             complement(13820..>14350)
                     /locus_tag="IXT46_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HAQ4948337.1"
                     /translation="INRSFNQLRVQIMNRFRTSHSENQKKYRRLKRYWKLLLKDSTTL
                     EPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLRYYFVKRGTEGFQETLK
                     TISSTLPQSFKKKFTIFHRYQSGISNAFKVSHSNGVTEGLNNKIKLIKRIAFGYRNFY
                     NFRARIYLQQGLIFEN"
BASE COUNT         4384 a         2433 c         2969 g         4564 t
ORIGIN      
        1 ttgaaaaacg ttgatttatc ggcattcccc atccatatta tatttacgtc ttattcccac
       61 tcaatatgag tagcctcgta aagaagctat tatatcagtg ctttttcagc ctattcctca
      121 ttttggtagg gaaatggtag ggttagattt ttactgcttg atttccatta aagtttgcaa
      181 ctttagattt tgttgcacag gtaaatttaa tgtttcctgt catttgttct gcaattcctt
      241 catcattacg gctccataga tgagcgtagt gctttaaagt gatttcaggg ctagaatggc
      301 ctaaccgttg cgacacgacc agaatgtctg cgttaaactc attgattagg tagctaacat
      361 gagaatgacg taatcctttt ccttgtatta ggggtacctt agctagtttg gcataacgct
      421 gaataattcg ttgaacagtt gaacgataga gtgggaggtc agtgtagcta agaataaatt
      481 gttctacacc atgatttttt tgaataactt tccacttttt tagcacttca attgtatcat
      541 cgtccagaga aatgatccgc aagccgcttt cagtttttgt gtaaggtttc cgaataaaat
      601 ctttttgatt tgtcatttcc aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca
      661 cgtcattcca attaagtgct aatccttcgc ttacacgaac accagtcatg taatatagcc
      721 agatcattaa aaaacacata tgttcgtaga aatcatcttt ataaattttt gccaaaactt
      781 cttcaaattc ttcttttgtc cagtaaggaa cgattgattt tccttttgga attgcttttg
      841 ttcttttgga aatattctca ttcagaaatt gcagggtgac cgcatagtct aatgatttac
      901 gaaacatacc gtacataagt gaactgtatg cttgtgagta tccgctatcg ttcaataacc
      961 aaattcgata attttcacaa tctcgcacat tgatttcacg aagcttctta tcaccgaaaa
     1021 attcagtaat ctgaatcaat ccacactcac gagaactcca agtacttttt tgtacgctag
     1081 ctttgtagtg tggaacgtaa gactgctcca taaattcttt gtaagttaaa tcataattcg
     1141 caaatccatt tacaaccatg tattcatttt ttatacgcat gacttctttg tgtgcttcac
     1201 gagctgatga gaatcgtttt cctagagaat cttttgttcc tttcttctgg atcctctttc
     1261 cagtcacttg atctgttcct aactcaacta gataagaaaa gcgaccattt ttatcttgat
     1321 acacacaagg gtattttgtt ttcatagtta ttcctcctgt gaaagaggaa cacctataat
     1381 ttcttcaatt acttgtcggg gtactacccc aactctttta ttattataat atggatatcc
     1441 ctgatttacc attcttgttt ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa
     1501 tcctagagcc tctaaatctt ttcgacaaat tgtatttttc attgtataaa ctcactttca
     1561 aagaaaacac tatcattggg taatagtgtt atttctttat ttttgtataa tgaacggtac
     1621 tttcttgaaa atccatcact tgttcaggac ttcccaactc atttaaagct aaagcattgt
     1681 aaaaaaatgg acgtctaact atatattcgc ttgtatatag tatatcttga ttcgtggaat
     1741 catagggttt ctttaccatc tttttggtga cagttggtag tttgagattc cgggacttga
     1801 aaaaagcttt tttcttatgc tctttcaatt ccagctcttt atcgaaatat ttgctgatat
     1861 agcgcccgcg attttcgata ctgtctacat cgatcttgtt gatcttaacg aaaccctgac
     1921 cccaaatcgt agttaaccgg ttaaatgaga taaaggggaa atcaaacaag ataatatggt
     1981 agtggattgc accgcgttgc tgcttttccc acgtggcgag atactttaaa tttgcttttt
     2041 tagttttata gaggtcataa ttcagtcgtt tgataaattt tttaaattca ttatttgcat
     2101 actcaatgtc ttgaatgttt tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa
     2161 aattcgtgtc tacaaggcgg gcaatctcaa atcgcatact ttgataatgt ttctgtttgc
     2221 gttttaaact gtcatattgt ccttgagcgg ataattcatc atagtttttt cttttttcaa
     2281 gagtaatatc attttcataa atccaagcta atttttgttt tcgttccaga tttacttcgt
     2341 tttcgatcgt tttacgtttg ggagtaatga ttgcttcata atcataaatt tcaatatacg
     2401 tgggagtttc aatgattttc tgattataag cttgcaaaaa tcatcactcc ttgttgcgta
     2461 ttcgattgtc aaagaaccag tcattttctc ctgatgttga tctataaatc aagttaaggg
     2521 ggaaggcctg cgtagcagcc cttctagcct atggggtgtt gggcggtctt aacggacaga
     2581 aacggctctg tgggcgctgc cccgccgttt cgtcctaacc acccaacact ccatagtata
     2641 gttagttttg tgtagtggta ccttgttttc tgggaatcaa agttgccgta tcagcggttg
     2701 ccgataaccc ataactgaca aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat
     2761 tggtaaatgt aattatggct aaaccttgtt gggtaagttc ttccggcgtg atcacaggat
     2821 gttcagattt gactttgaca ctgatttttt cgtagcgaag ttttggtagg atacattcgt
     2881 agctccaacc tagaatttcg ccctcctttt gccagcgagt gacattgacg acttggtatt
     2941 ctttttcgag tgtttctttt ggtaaactga gatcggtaat ttttattggc atcacaattc
     3001 tcctttttta tacgaaagtt tatacgattt gattaaaaaa tatagatggc catctacgac
     3061 ttgtattata tacgagaact tatacgtagt caagagattt tctaaaaaaa tatatacgat
     3121 tttttatacg agtgttataa tgaaaaaaat gataaggagg aatttgaata tgtttggttt
     3181 agtacaacct aataaagtga aggtgggcca acgaatcaaa gaaataaaag acggaatgtc
     3241 tctctctttt acagaattag ggaatcgatt aggtttaaaa aagccgacga tcagttccta
     3301 cgttcaaggc tatgcgttgg ctcctaagag tgtgatcaac caattatcta gtatcagcgg
     3361 aaaacctgtc ggctggtttt attttgggca tgtggaagaa tatatccgag agtatttgtt
     3421 tctcattggt cagaaaaaaa tagtggacga ttatcctgaa atcattgaga aaataaagca
     3481 agaattttat acgggcgagt tcaaaaatcc tgcttgggag aatgagctag gctatccttt
     3541 ggaggaattt atccaagaat gttttgtaga atattcgagt gaaatcatga aggactatgt
     3601 cgtacagatt acgaaagagg tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa
     3661 agcaaaagaa gaagctgtca cgattctttc atctgggatc attgactata tcgagatgag
     3721 tggtgagatc aagtatggag agaaagatcg cattgcgaaa atggtgaaag aatcaataaa
     3781 aacctttgat gtgaaacaag acctgacatt taatgattcc tatttgattg gaaagttgat
     3841 caatattctt ggtacagatg aagatacgga gctgtttctt tcttctttat caatgatatt
     3901 tactgataag catttttcca ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc
     3961 gatgcgacca gcgttaatca aactctatcg ggagaaaaca ccagatgaat tttatgattg
     4021 gtttgagaag taaaataaga aaagtggctt agattacaag ttggtgaaaa aatttttttc
     4081 agcataacat cagtaatcta taaaggggtt gttgattata ctgtagaagt taagtactca
     4141 agagattttt tgtacgtaaa caaagcaaaa aagggtgcag tttcactaga aaatgtactc
     4201 ttttttgtga tttttcttag ttatagagtt tttttgaaac tttaaaaatg agaaaacata
     4261 ttgattttaa agagtgtaga catagcttct tttgctaaat agattaaact tactggtgag
     4321 tggtcttgaa catactttta aatcacattt tactgagttt tattggattt tataattcat
     4381 tggaaacctc gtacttaatc tgtttttatc tatcgactag aatctgtata tattccagct
     4441 atcaatgagg ccgcagaaaa gggtgcttaa aaataatctg ttgtttaaaa tattattatc
     4501 agaatactta gatacaaaat tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg
     4561 atatggtaat ctataaacga aaatagtggt aacgtttcca aaatgcatct tcgttaaatt
     4621 tttatttttt taaacgaaaa tggaaacgtt tctaaaatgt attgggagga gattgaattg
     4681 gaaaagacat tgggaccagg tggtgagata agggcggtac aacgggataa aaaaaatatt
     4741 tcgaagtggg aaaaattaaa gaaacagttg cggcgtgata agtggatgta cttgttgctc
     4801 ttaccaggta tcatcatgac gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt
     4861 gcatttaaag actataatcc tatgctagga attttggaaa gtccttgggt aggactagat
     4921 cactttaggg aatttatcag ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa
     4981 attagtattt atggtttatt gttaggtttt tttccaccaa ttattttagc actgagcttg
     5041 aatcaaatta tcaataaaaa aataaaacag aaaatccagt tgattctata tgcgccgaat
     5101 tttatctcag tagttattat tgtggggatg ctgtttttgt tcctatccgc aaatggacct
     5161 attaatgggt tagtagaaaa ggttacgggg caaccaatta tgttcatgtc taatccagct
     5221 tatttcagaa cgatttatat tttatcggga atttggcaag gaatcggctg gtcatccatt
     5281 ctttacaccg caacgctggc gggagtcagt accgatttat atgaggcagc aaatatcgat
     5341 ggggcaaata ttttacaaaa gatttggcat atcgatttgc ctgcattgag gcctgtgatg
     5401 gtgatcagct tcatcttggc cgccggcggt attatgaatg taggatatga aaaagcctac
     5461 ttgatgcaaa cttcaatgaa catccctgcc tcagaaatca tttccactta tgtatacaaa
     5521 gtcggcttgc aatcaggtga ttatgcctac tctgctgctg ttggtctgtt caatatgatt
     5581 attaatgtcg ttttattact gattgtcaac aatataacca agcggctaaa cgatggtcaa
     5641 ggcttgtaat gaaaggagaa aattatgaat agtgctttat caaaaatcga ccgtcaaatc
     5701 ttatggttga atcgagtgat tgtaactttt ttagtcgtca tcaccattgt tccgctgatt
     5761 tatgtactgg tagcttcttt tatggaccca gctactttga tcaataaagg tataagcttc
     5821 aatccgaaag attggacaat acagggatat caacgggtat ttgcagatga ttccatttta
     5881 cgcggttttg taaattcgtt gttttactct tttagcttca gcttattgac tgtatttatt
     5941 acgatgatca ctgcgtatcc tttgtctcga cctaacttgg cggggaaaaa gattattatg
     6001 actttttttg tcattacaat gttcgtgggt ggtggcttga tacctaccta tttattggta
     6061 aagaacttgg gcatgttaga tagtgtatgg gcgattatcg taccaggtgc tataaatgtg
     6121 tggaatatta tcttagcccg tacctatttt agtgctttgc caaaagaact ttctgaagct
     6181 gctactatcg atggcgccaa tgacttgcaa atactgttca aagtcatgct tccattagcg
     6241 aaaccaatta tgttcgtatt gtttttatat gcctttgttg ggcaatggaa ctcatacttt
     6301 gatgccatga tttacatcaa agatcccgac ttacagccgt tgcaactcgt attaagaaat
     6361 attttgatcc aaaaccaacc ttcacaagac atggtgggag ccaatactgc catggcagaa
     6421 atgaaacaaa ttgctgagtt gatcaaatac gcaacgatcg tcatttctag tctgccatta
     6481 atcataatgt atcctttctt ccaaaaatat tttgataaag gtgttttagt tggttctgtt
     6541 aaagggtaag tattgttcac tatttgtatg aataaaaatt ataaaggaga ttttaagatg
     6601 aaagcaaaat ggatgctgcc aatcgttttt acttccgtac taattttggg ggcttgtgga
     6661 ggctcaaaag aaaagagtaa atcaagccct gattatgaac tagaaaatgt ctcttttcca
     6721 ttgaaagaaa aagtatcttt aaaaatgatg tctcaaagtg cccctttggc tcccaatgat
     6781 cctaatgaca aattgatttt ccaacgatta gaagaagaga ccaatctcca tattgattgg
     6841 acaaactaca gtagtgattt tgccgaaaaa agaaatttgg atatcgctag tggtgattta
     6901 ccagatgcca tcttcaacgc cgctgcaggt gactatgatt tattaaactg ggcggaaagt
     6961 ggcgttattg taccgattga agatttgatc gaagattata tgccaaatct gaagaaaatt
     7021 tttgatgaaa accccgaata ccgacaaatg tctactgcac ctgatggtca catttactct
     7081 atgccttgga ttgaagaatt aggcgaagga aaagagtcga ttcatacagt aaatgggatg
     7141 gcttggatca acaaggagtg gttggataat ttgggtcttg aaatgccgca aaccactgat
     7201 cagttgatga ctgtgttgga ggctttcaag acgcaagatc caaatggtaa tggtgaagca
     7261 gatgaaattc cttttagctt tattaacaat ggaggaaacg aagacttaaa atttttaatg
     7321 ggggcattcg gtctaggtga taatgatgac cacttagtcg ttgataacga tggtcaggta
     7381 caatttactg ctaacaaaga agggtataaa gaagccatca aatatttcaa tgaaatgaat
     7441 aataaaggtc ttattgataa agaggctttc gaacaagatt ggaatacgta tgttgccaaa
     7501 gggaaagaac ataagtatgg cgtgtacttt acttgggata aagcaaatat cacgggtgca
     7561 gatgatagtt atgacgtctt gccagtctta gcgggaccag atggaacgaa acatgttact
     7621 cgtacgaatg gcatgggttt ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac
     7681 ttggaactta cagctaggtg gatagataaa atgtatgaac cgttacagtc tgtccaaaat
     7741 aactggggaa cctacggtga tgaagcacag gcgaatattt ttgaattaaa ggatggtatg
     7801 ttaaaacatt tgcctttaga ggggacagca ccgggggaac taagacaaaa aaccgaagct
     7861 ggaggaccat tagcagttct tgattcttat tacggcacag tcactactat gccagatgat
     7921 gcgaagtggc gtttagattt gatgcatgac acgtatttgc catatattac agaagacaat
     7981 atctatccac gtgtcttttt agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg
     8041 gatatgtggg attacatcta tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat
     8101 gaagaatggg aagaatacct tgctgaattg gaacgtgtag gtttggaaga atggattcaa
     8161 ataaaacaaa ctggctatga taattttttg aagggagcac aataagtgtt agtagaagaa
     8221 acggcgattt tggataaagc aaatcgattt attgaaatga tgcgaggaaa agttaaccct
     8281 cagtatcgac aaaactatca tttttccgca cccatcgggt ggataaatga ccccaatggg
     8341 tttatatatt acaaagggca ttaccatctc ttctatcaat actatcctta cgatagtcga
     8401 tgggggccca tgcattgggg gcatgcgcgc agtagtgatt tggtccattg ggaagatcta
     8461 ccagtagcgt tagccccaga tcaaccttat gacagcggcg ggtgtttctc aggaagtgca
     8521 attgaaagag acggaaaact atatttattt tatacaggct gtcaagaaat tgatggtatt
     8581 agccatcagc atcaatgttt ggcggtctct gaagatggta ttcattttag caaatacagt
     8641 ggtaatcctg tggtagcaga aaaacagcta ggtgaaaatg ggctaataca agaatttcgt
     8701 gatcctaaag taattgttca caacgatggt tactatatgg tagtagctac taaatctaca
     8761 cagtctactg gtagaatagt gatgtttcaa tcgtcagatt tgtatacttg gcacttttac
     8821 tctgtgctgc tagaagggac ttcagagcaa ggaataatgt gggaatgtcc tgatttattc
     8881 catttagacg gacgagatgt cttaatcatg tctccgatac aaatcaagaa gaacggactg
     8941 gaatatcata atatcagttc taccatggct tgtattggtg aggtaaactg ggaaacaggt
     9001 cagatgatag ttgataattt ccatgaaatg gattttggaa tggattttta tgcaccacaa
     9061 acaacaagag atcctaatgg tggacgggtg atgattgctt ggatgcagat gtgggatcgt
     9121 acattgccta cacatgagtt aggccatctt tgggcaggct ctatgagttt gccccgagag
     9181 ttaagagtga aaaaaaatcg attggtacaa aaacccatct caactgtata tagtcattta
     9241 gtttatcaac aaggcagtga aaatattgca gtgactgaca catcagtcgt atttcgaaac
     9301 gcgctgtctg attcttcata tttacatcta gtcgcagatt tggagaaagc tgaagttttt
     9361 acaattgaat tactgcggtc taagacggat tgtctcaaac tagcctatga cactgctaca
     9421 caggtttttg aattggatcg tcagaaacta ggaagagagc ttacaggggc ggaagaagac
     9481 cctctgaatg tacgaaaagt tgaagtacct ttgattgata atcagctcgt tcttgagatt
     9541 tttagagata cctcatcaat tgaagtcttt attaatgggt tagaagttat gacggctact
     9601 ttctatgagc tggaaaaagc tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt
     9661 caagcttttg aaacagcgag tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt
     9721 atttaatagg ttttgaagga taatgttttt agaaaagaac agatagctag atttcccatg
     9781 gatttgctat tagtattttg aaaaaattag taatttatga caaaattcat tatactaaac
     9841 ttgtgcagaa atgtgaggga tcaactatga aagcaacaat gaaagatgtc gcaaaattag
     9901 caggtgttgg agtaggaact gtttcccggg tattgaataa cggttctgtt aaagcttcta
     9961 ctagagaaaa agttgaagca gcaatgacag agttaaacta tcaaccagat ttttatgccc
    10021 gggggttaaa gatgaagcat acgaacacgg ttgctttgat tctacccacg gtatggcatc
    10081 cattttttgg cgaatttgcc taccatgtag aaacagcatt agaaagacaa aactacaagc
    10141 tttatttgtg taactccagt ggtaatagtg aaaaagaaca agaatatatc cagatggtca
    10201 gccaaaataa agtagacggc atcattggaa ttacttattc agatatcgat gaatacattt
    10261 cgagtaatct gccttttgtt agtattgacc gttatttcac tgaagaggtg atttatgtga
    10321 ccgctgacaa tgcggccggt ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc
    10381 agaatgtagc atatatcggt gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa
    10441 aatattttga aatcgagtgc cgtcaactgg ggatttccta taaagcgtta gatatgttag
    10501 aacctttaga ccatctctca gaacgtgtaa caaatttttt gttagagaat cccgatatcg
    10561 atgggatttt tacgatcaac gatccaatgg cattagctgt cattgatatg cttgaaaaaa
    10621 tagggaaaaa cgtaccagag gatgtccaag ttatcggatt tgatggtcaa aagatgacag
    10681 aaggagatcc ttatctagtc tcaacgattg cccaacctac aaagcaaatg gcggaagtgg
    10741 cagtggcaaa attaattgct gtcattaatg gagagacagt agaaaaacgt accgtattgc
    10801 cgattgaatt tggcgaaggt gacacaacga aacctttagt gagaaacgat tttgcttagt
    10861 gcaaatacgt ttcttttttt gaaaatgagt gaatgaaagg tgtagataaa atgttatatg
    10921 gtggaataga agccggtgga acaaagtttg tctgtgggat tggtaatgaa caattacaag
    10981 tgatagaacg gaaaagtttt cctaccacaa caccagaaga aacgatggag caagtgtttg
    11041 atttctttga taagtacaaa ggaaatatcg catcaattgg tgtaggagca tttgggccta
    11101 ttgatattca aatcgaatca agaacttacg gatatatcac caacacaccg aagttagctt
    11161 ggcaaaatta tcattttgta ggagctttgg aaaacgcctt gtcggttccc atctattgga
    11221 ctaccgatgt aaatgctgct tgttatggag aatatatggc agggtatgga aaaggtaaaa
    11281 atagtgttct gtattacacc gttggtacag gtgttggtgg tggtgctgta gtggatggga
    11341 aaatagtcgc aggttttagt catcctgaaa tgggacatat gctcttacaa cgtcataatg
    11401 aagatcaatt tgaaggaatc tgtccttttc atcatgattg tttggaaggg ttagcatcag
    11461 gacctgcgat tgaaaaacgc tttggaagaa aagcccagac tatctcattt gatcatcctt
    11521 attggacgat tgaggcagat tatcttgctc agtgtgtgta taacacaacg ttactatatg
    11581 caccggaagt aataatttta ggcgggggtg taatgaaaca gccgcaacta ctcgagttga
    11641 ttcgccaatc gtttaaagaa aaaatgggtt cctacgtgga tacgcctact ctcgaagaat
    11701 atctactaac tccaaggctt gctgacaatg cgggcttgat tggctgccta gctttagcaa
    11761 taaagaaact caatcattag aatagtattt attagaacta ttcataacat accggaagtt
    11821 taaaagggta ttctgaaact taaatagtct caattcattc ttctttcttg agaatctgag
    11881 tagagacttt tattctgttt caaattaata taattacgaa atgatattga gtacaagaaa
    11941 gttcttttta ccagatcttt taaatcgaaa aatctgatat atatatttat agtactaaaa
    12001 atctgattag ataaaaagct aattcaatag gaaaataaag gtagtgaata aaagcaaagc
    12061 ccttgttagt agttaatcta acaagggctt tggtagggaa aatggtagga aaccatctta
    12121 ttttttacga aaatcaggaa ctttagtaat tgaataatgt tgatttatag gtattcctca
    12181 tccatattat gttggctctt tattcccact ccactgttgc aggtggtttg ctggtaatat
    12241 catacacgat acggttaacg tgtgcgactt catttacgat acggacactg attttttgca
    12301 agacttccca agggatacgg gcaaagtcag cggtcatgcc gtcaatagaa gtgacagcac
    12361 ggatacctac agtgtagtca tacgtacggc catctcccat aaccccaaca gagcgaatgc
    12421 ctggtaggac ggtgaagtat tgccagatgt cgcgatctaa accggcattg gcgatttctt
    12481 cgcgcaagat agcgtctgat tcacggacga tttctaattt ttcttctgtc aattcaccaa
    12541 ggacacgaat acctaagcct ggtccaggga atggttggcg ccaaacgatg ctgtcaggca
    12601 tgcctaattg ggtacctaat tcacgtactt cgtctttgaa caatgtgttc aatggctcga
    12661 tcagcttgaa ttgcatgtct tcaggtaatc cacctacatt gtgatgtgat ttgatggttt
    12721 gggcagtttc agttcctgat tcgatcacat cggtataaag ggttccttgt gcaaggaaag
    12781 aaacgccttc ttcaccggca agtttggttg cttcatcatc gaagacatat acaaattcat
    12841 ttccaatgat tttacgtttt tcttctggat cagacacgcc agcaagtttt gataagaaac
    12901 gttctttggc atcgactttt ataatgttca agccaaattt tccgccaaga ctttccataa
    12961 cttgttctgc ttcaccttta cgcaacaata cgtgatcaac gaagatacat gttaattgat
    13021 cgccgatcgc tttttgtaaa agaacaccaa caacagagga atctactccg cctgaaaggc
    13081 ctaataaaac ttttttgtca ccgacttgtt cacgaatttt tgcgatctcc atgtcgatga
    13141 agttatccat tgtccagtca ccagtacatt ggcagacatc tagtgtaaaa tggcgcaaca
    13201 agtcatttcc atattcggaa tggcgaactt ctgcatggaa ttggattccg tacattttgc
    13261 gttctgcatt ttggatcgat gcgatggggc aatctttgct ggtagcaacg acatcgaaat
    13321 cagtcggtgc ttgggtaact aggtcaccat gactcatcca aacggtttgt ttttcaggag
    13381 tgttttggaa aagggccgct tctgcagaag tgatttccaa ttctgctttt ccgtattcac
    13441 ggtttttggc tggtttaact tttccgccta atttataagt aatcaactgc ataccgtaac
    13501 agattcctaa aactgggatc cccaaatcaa aaatcttttc atcaatacca aaggccttct
    13561 catcataaac actgtttggt ccgccagaaa ggatgattcc tttagggttc attgccttta
    13621 cttcttctgc ggtaatgcgg tggctcatca actctgagaa aacaccgaac tcacgaatac
    13681 ggcgagtgat cagttggtta tactgactac cgtaatcaag tacgataatt tttggctctt
    13741 cgtcaaatcg tgttggtgaa gacaaatttg aataaaactt agtccgatat gcggcgcgtt
    13801 ctgtgcgccg catatttttt tagttttcaa agatcagacc ttgttgtaaa tagatccgtg
    13861 cccgaaagtt ataaaagttg cgataaccaa acgcaattcg tttaatcagc ttgatcttgt
    13921 tattcagccc ctcagtgacg ccgtttgagt gggacacctt aaaggcattt gaaatacccg
    13981 attggtagcg atggaagatc gtgaatttct ttttaaacga ctgaggtaac gtagatgaaa
    14041 ttgttttaag ggtttcttga aagccttccg tacctcgttt aacgaaataa tagcgtaata
    14101 attgacaaaa atgatacgca gttcgcaatt cttcgttgta gcttaacagc tcatcaacga
    14161 tttctgtttg actaattggt cgtttaaaca gtcgatgata atgccgtttg agtggctcca
    14221 atgtcgtgga atctttgagt aagagtttcc aatatcgctt gagccgacgg tacttcttct
    14281 gattttcaga gtgtgaggtt cgaaaacgat tcatgatctg gacacgtaat tgattgaagc
    14341 tgcgattgat
//
LOCUS       DACGMI010000071        14099 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.073, whole genome shotgun sequence.
ACCESSION   DACGMI010000071 DACGMI010000000
VERSION     DACGMI010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.073"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(11..3664)
                     /gene="rpoC"
                     /locus_tag="IXT46_002445"
     CDS             complement(11..3664)
                     /gene="rpoC"
                     /locus_tag="IXT46_002445"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAQ4948338.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(3743..7360)
                     /gene="rpoB"
                     /locus_tag="IXT46_002446"
     CDS             complement(3743..7360)
                     /gene="rpoB"
                     /locus_tag="IXT46_002446"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAQ4948339.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8088..9056
                     /locus_tag="IXT46_002447"
     CDS             8088..9056
                     /locus_tag="IXT46_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4948340.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9074..9979
                     /locus_tag="IXT46_002448"
     CDS             9074..9979
                     /locus_tag="IXT46_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4948341.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            9976..10782
                     /locus_tag="IXT46_002449"
     CDS             9976..10782
                     /locus_tag="IXT46_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4948342.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10939..11907
                     /locus_tag="IXT46_002450"
     CDS             10939..11907
                     /locus_tag="IXT46_002450"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAQ4948343.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12224..12748)
                     /locus_tag="IXT46_002451"
     CDS             complement(12224..12748)
                     /locus_tag="IXT46_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAQ4948344.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13035..>14099
                     /gene="scm"
                     /locus_tag="IXT46_002452"
     CDS             13035..>14099
                     /gene="scm"
                     /locus_tag="IXT46_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAQ4948345.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT         3990 a         3042 c         2785 g         4282 t
ORIGIN      
        1 tttaaaatat ctattttgtt tgattgttca ttgcgtcttc tgcagccatt tgcgcttcaa
       61 tatctgaaat actgtagaca ttttcgcttg ctacaccgac ttcttttggt tccatgtcac
      121 gataacgttg cataccagta ccagctggga tgatcttacc tataataaca ttttctttca
      181 aaccaagaag aggatctttc ttaccgcgga tcgcagcatc cgtcaagaca cgagttgttt
      241 cttggaatga tgcagcagat aagaaactat ttgtttctaa tgatgctttt gtgataccta
      301 gtaagacagg tcgagaagtt gcaggaacgc ctcctgagac tagcgtattg tagttttgat
      361 ctttaaagtc tgcgatgtct aataatgtac ctggtaagat atctgtatca cctggatcca
      421 ttacacgaac tttacgcagc atttgacgaa ccattacttc gatatgcttg tcgccgattt
      481 ctaccccttg catacggtaa acacgttgta cttcacgaag caagtagttt tcaacagata
      541 atacatcgcg aacttgcaac aattgttttg gatcgattga tccttctgtc aatggtgcac
      601 cacggtggat catatcgcct tctgctactt tcatacgtgc tgtataagga acagtatacg
      661 tacgtgtatc tgtttttcct ttgattgtta cttctttggt acgtgttgca ggatcttctg
      721 agatatcgat gacatcccct gttacttctg tgatcactgc ttgccctttc ggattacgtg
      781 cttcaaagat ttcttggaca cgaggaagac cttgagtgat atcgtctccg gcaaccccac
      841 ctgtatggaa tgtacgcatc gtcaactgag taccaggttc accgattgat tgagcggcga
      901 tcgtaccaac tgcttctccg acttcaacgt cagagccagt tgcaaggttg cgtccgtaac
      961 aatgtttgca gacaccatgt tttgtattac atgtgaagac agaacggatt gtcactgttt
     1021 cgacacctgc atcaacgatt tgttttgcga tgtcttcgga aatcaattgg tttcctgcaa
     1081 tgatcaattc atttgtttca ggatgacgta cttctttacg ggtgtaacgt cccactaaac
     1141 gatcttctaa tgattcgatg atttcatttc cctcgcggat ggcttggatt tcaagacctc
     1201 ggtcagtacc gcaatcttct tcacggatga ttacatcttg ggccacgtca accagacgac
     1261 gagtcaagta acctgaatcg gcagtcttca aggctgtatc ggtcatccct ttacgagccc
     1321 cgtgagttga gataaacatt tccaagacgg atagtccttc acggaagttc gaaatgattg
     1381 gcaattccat gattcgacca ttaggagcgg ccatcaaacc acgcattccg gcaagctgtg
     1441 taaagttgga aatgttacca cgagctccag aatcagacat catgaagatt ggatttttcg
     1501 cttccaaacc ttccatcagt ttttgttgga tgctgtcttt tgcagcattc caaacagcaa
     1561 tgacacgttc ataacgttcg tcatctgtga tcagaccacg acggaattgt tttgtaatag
     1621 tttcaacttg tttatgggca ttttcaatga tttcttgttt ttcattcagt acactgatgt
     1681 cagcgatccc tactgtgata ccggcatgtg tcgaatgttt gtaccctaag tctttcatac
     1741 ggtcaagcat cttagaagtt tctgttactt tgaatcgttt gaagacttct gcgatgatgt
     1801 ttcctaagtt tttcttcttg aacggtaata ctaattcttg ctctttgata tgtgcaggaa
     1861 tatcagtacc agcttcaaca aagtatttgt ccggtgtttg gacggtcaag ttgaagtctg
     1921 ttggttcatt cagataaggg aattcaggag gcatgatctc gttgaagatg atcttaccaa
     1981 ctgttgtgat catcgtacgt tctttttgcc attcagtaaa tggtttttca cctaatgagt
     2041 tagggttcac accgatacgt gaatgtaaat gaacatatcc gttgcgccat gcgataacgg
     2101 cttcgttttg atctctgaag accattcctt cgccttcgcg tccttcttct tccattgtca
     2161 agtagtagtt acctagaacc atatcttgag aaggagtaac aactggttta ccatctttag
     2221 ggttcaagat gttttgagca gctaacatca acatacgtgc ttctgcttgt gcttcttcat
     2281 tcaatggaac gtggacagcc atttggtctc catcgaaatc ggcattataa gcttcacata
     2341 caagtggatg caaacggatt gcgcgtcctt gtactaaaac tggttcgaat gcttggatac
     2401 caagtcggtg aagcgtaggt gcccggttca gcaatactgg gtgttccttg attacgtctt
     2461 ctaaaacatc ccatacttcg tcttcttgac gttcgatttt acgtttcgca tttttgatgt
     2521 ttgaagctag ttcgcgttga acaagctcac gcatcacgaa tggtttgaat aattcaatgg
     2581 ccatttcttt tggaagtcca cattggtaca tcttcaagaa aggtccaaca acgataacgg
     2641 aacgacctga gtagtcgaca cgtttaccta gcaagttttg acggaaacga ccttgtttcc
     2701 ctttcaacat atgagaaaga gatttcaatg ggcggttacc tggtccagta actggacgtc
     2761 cgcgacgacc gttatcgatc aatgcatcta ctgcttcttg cagcatacgt ttttcatttt
     2821 gaacgatgat tccaggtgca ttcaagtcta acaaacgttt caaacggtta ttacggttga
     2881 ttacacgacg gtaaagatca ttcaagtcac ttgttgcaaa acgtccacct tctaattgaa
     2941 ccattgggcg taaatctggt ggaataacag ggataacgtc cataaccatc cagcttggtt
     3001 gatttcctga agcgcggaat gcttctaaaa tatccaaacg gcggattgca cgtgtacgtt
     3061 tttgtccttg tgcagatttc aattcttctt tcaattcggc tgcttctgca tctagatcaa
     3121 cattatcaag taattgttta atcgcttctg cacccatagc agcttggaat tcttgtccat
     3181 attgttcacg tttttcgcga tattcgcgtt ctgtcaacaa ttgttttttc tctaaattcg
     3241 tatttcctgg ttcgatgact acatatgaag caaaataaat gatttcttcc aaagcgcgtg
     3301 ggctcatgtc taatacaaga cccatacgtg aaggaatccc tttaaagtac cagatatgtg
     3361 aaacaggagc tgctaattca atatgtccca tgcgttcacg gcgaactttc gaacgagtaa
     3421 cttccactcc gcatcgatca caaacgattc ctttataacg gatacgtttg tattttccgc
     3481 aggcacattc ccagtctttt gtaggaccaa aaatccgctc acagaacaac ccttcgcgtt
     3541 caggttttaa ggtacgatag ttaatcgtct caggtttttt tacttcaccg taagaccagc
     3601 ttctgatttt ttcgggagaa gccaaaccta tttgcatact ttcgaattta tttacatcga
     3661 tcaaaagggg ttccctccat ttcatttaat ggcaaaccgc aagacggctg atcttcgacc
     3721 gccttgcagc tcatagaccg gattagtcta aattatcttc tgcggtttca aagttttgga
     3781 tgacatcgtc tttttcatct tccacttgtt cagcagcttt cttttctaat tctttggcag
     3841 tttgctgttc ggcaaatttt gtcaaagcat caacagtgat caaatcgtcg tcttcatcgt
     3901 ccatgtcgcg aagttcgatc tctgtttctt cgatatccaa gacacgcatg tccagaccta
     3961 gtgattgcaa ttctttcacc aatacgcgga atgattccgg tacacctggt tttggaattg
     4021 gttcaccctt gacgattgct tcgtatgttt tcacacgtcc gactacgtca tctgatttgt
     4081 atgtcaagat ttcttgtaaa gtataagccg caccgtaagc ttccagtgcc catacttcca
     4141 tttcaccaaa acgttgtcca ccaaattgag ctttacctcc caatggttgt tgtgtaacca
     4201 atgagtaagg tccgattgaa cgtgcatgca atttgtcatc gaccatgtga gcaagtttga
     4261 tcatgtacat cacaccgaca gacacacgtc catcaaatgg ttcacctgta cgtccgtcgt
     4321 acagaacagt tttcgcatcg ctggccatac cggcttcacg aactgtttcc catacgtctt
     4381 catcacttgc accatcaaat actggcgttg ctacgtggat acctaactga cgtgcagcca
     4441 tacccaagtg taattccaat acttgcccga tgttcatacg tgaaggcacc cctaaaggat
     4501 tcagcatgat atcgattggt gttccatcag gtaggaatgg catatcttct tccggcataa
     4561 tacgggatac aaccccttta tttccgtgac gaccggccat tttatcccct tcatggattt
     4621 tacgtttttg aacgatataa acacgaacta acatgtttac gcctggtgac aattcatctc
     4681 cagcttcacg agtaaagatt ttcacatcgt gaacgatacc gccgccgcca tgtggtacac
     4741 gtaatgatgt atcgcggact tcacgagctt tttcgccaaa gatcgcatgc aatagacgtt
     4801 cttctgcaga taattctgtt accccttttg gcgtgacttt ccctacaagc aaatcgccat
     4861 cttggacttc tgcaccaata cggatgatac ccatttcgtc taaatctttt aatgcgtctt
     4921 ccccgacatt agggatttcg cgtgtgattt cttcaggtcc taattttgta tcgcgggctt
     4981 ctgattcata ttcttcaata tggatagaag tgtatacgtc atcttttacc aaacgacggc
     5041 tcatgatgat cgcatcttca tagttgtacc cttcccaagt catgaaacca actaaaacgt
     5101 tttggcctag agccatttcg ccttgttcca tagatggtcc gtctgccaga gtatcccctt
     5161 tttcgacttt ctcacccaaa tgaacgattg gacgttggtt gtagcttgtt ccggagtttg
     5221 aacgacggaa ttttgttaca tcgtatttat ctaatgcacc gttgtcgcgg cgtacgcgga
     5281 tttcagaagc atcaacgtat tcaacgacac cgtcatgttt acataacaaa gcagctcctg
     5341 agtcatgcgc tgatttgtat tccataccag taccaaccca tggtgcttga ggattgatca
     5401 acggcactgc ttgacgctgc atgttggcac ccatcaaggc acggttggag tcatcgtttt
     5461 ccaagaaagg aatacatgct gtcgcaacgg caactacttg tttaggtgat acgtccatgt
     5521 agtctacttt atcaatagat acttctaagt tttcactttg agcacgagcc ataacaacgt
     5581 cttgagcaaa tgttccatct tcattcaatg ggctgtttgc ttgggctacg atgtaatggt
     5641 cttcgatatc agctgtcaag tagtcgattt ggtcagtaac acgacctgtt tcacggtcta
     5701 cacgacgata aggtgtttcg ataaatccga atttatttac tttcgcataa ctggacaaac
     5761 tattgatcaa cccgatgttt gggccttcag gagtttcgat cggacacata cggccatagt
     5821 gggagtagtg aacgtcacga acttcataac cggcgcggtc acgagtcaat ccgccaggtc
     5881 ctaaggctga aagacgacgt ttgtgtgtca attcgccaag agggtttgtt tgatccatga
     5941 actgtgacaa ctgagaagaa ccaaagaatt ctttgatact tgccacaact ggacggatat
     6001 tgatcaattg ttgaggtgtc aatgtttcag tatcttggat cgacattctt tcacgaacca
     6061 cacgttccat acgtgctagc ccgatacgga attggttttg taaaagttca ccgactgaac
     6121 ggatacgacg atttcctaag tggtcgatat catcgacatt gccgatacct tccatcaagt
     6181 tcaagaaata gctcattgaa gcaatgatgt cggctggacg aaccgttttt acagctgctt
     6241 ctggatagcc gtttccgatc acgtttactt cacgttcagg gtctcttggt gaaaatactt
     6301 tgatgacttg gacagtcatt ggatctgtga ccacaccgtc ttctgatgga tagtaagtca
     6361 ctgaatttag gccattatca atgaaaggag ctagtgtttc catgacttgg tgagtcagaa
     6421 ctgttccttt ttcaacgatg atctcgcctg tttctggatc aactaatgtt tcagctaatg
     6481 tcagattcaa tagacgtgtt ttcaaatcta attttttgtt tactttgtaa cgaccaacgt
     6541 ttgctaagtc gtaacgtttt ggatcgaaga aacgagcatt cagcaagtta cgtgagctgt
     6601 ctgctgtttt tggttcgcct ggacgcaaac gttcgtaaac gtctttcaaa ccttcttctg
     6661 ttcttgagtc gcttgcgttt ttatgcaagt ctttttcgac tgtattgcgt aatgtttcgc
     6721 tgtcgccgaa gatttcaaag atcgtatcat cggaaccaaa tcctaacgca cgaactaata
     6781 cggttaaagg aatcttacgt gtacggtcga tacgtacata agagatgtct tttgcatcag
     6841 tttccatttc tagccaagct ccacggttag ggataacagt agaaccgaat ccttcttttc
     6901 cgtttttgtc gacttttcca tggaaataga cacctggtga acggactaac tgagaaacga
     6961 ttactcgctc tgccccgttg atgatgaatg ttccttgttc tgtcattaat gggaaatcac
     7021 cgaagaatac ttcttgtgct ttgatttcgc cagtctcgcg gtttgtcaaa cgcaatgtta
     7081 catgtaatgg tgcagagtag tttgcatcat gcgcacgagc ttctgctact gtatactttg
     7141 gttctttcaa ttcataatct acaaattcca aagatagatt gccattgaag tcatcgattg
     7201 gcaaaatgtc ttcaaacatt tctctaagtc cctcatctaa gaaccattgg taagagtctg
     7261 tttgaatttc gatcaaattt ggtaattcca acacttcact gattcttgcg aaacttctac
     7321 gttcgcgatg ttttccgtat tttactacgt gtccagccaa gctcttcacc cctctaaaat
     7381 gtcattcaaa aagactaccc gatcaattgt tacaataata tttcaaatat tatttttagg
     7441 taacaacaga cattttttgc ggcttttagg caaaaaaaaa ccaaaaatag aacattctct
     7501 tgaaacctta cttcgtgagc ttctactttt gtttccttat attaaagccg aaacggacaa
     7561 tatttcgttt ctgccttttc ttcatcagat agtttttgca acttcatata ctacacttat
     7621 tttctataaa agtcaacact tcctggcgtt tcttctgctt tttcgcaaca ttttcttaat
     7681 gttttcaatt ttatgttttc aattatctga caattcttaa ttgacagacc tttttatctc
     7741 ggttatactt tagaaaattc attttgtgga ggaacttcta tgcgaaccaa catcaaccaa
     7801 atcgcaccaa cacaactgaa taacttttac tttagctact ttagataggt ttgtattcat
     7861 catgatggat acaaacgtta aacgacagtt tgtatctatg atggctaaag aactttgtat
     7921 tgcagcaaaa agccacgtag acaaaatgct aagtggctga gcagtgaaaa tacaaagtaa
     7981 aagtatcaag cattctactt tttcaattta ttttccgact tttcaatcca tttggacatt
     8041 ttgtctgaat ggattttttg tttcccaaaa ttaaggagga aaaagaaatg aaaaaaaata
     8101 taatcatcgg attaggcgct gccctgctac tagctttagg aggttgcgca caaaaagaca
     8161 attccgcaga ggcatcagat ggacaaaaaa caattggcgt attgcaactt gtacaacata
     8221 actcgttaga tgctgcctat aaaggattca aagaaggatt agcagaagaa gggtataaag
     8281 aaggcgataa tctaacaatc gattatcaaa atgcccaaaa caatcaagac aacctgaaaa
     8341 gtatgagtga gaaactcgtc aaagaagatc ctgatttgct acttggaatc gccactccag
     8401 cagcacaatc tttattaaat gaaacaacca ctatcccgat gactgtcaca gcggtcacag
     8461 acttggaaca agcccattta gtcacatcca atgaaaaacc tggcggcaat gtgactggca
     8521 cgacagatat ggtgccaatc gaaaaacaaa tcggcttact gttaaatatc gtgccagacg
     8581 ccaaaacaat cggcatcatg tataacaacg gtgaagcaaa ctctaagatc caagctgatt
     8641 tggcagaaaa agaattgaaa aaagcgggcg tcaaagtcaa agtactgaca gcaaattcca
     8701 caaatgatgt ccaacaagtg acgaaaagtc tagctaaaga tgtagatgga atctatattc
     8761 ctactgataa cacgttcgca agtgcggcaa gtgttgtcgg tgaagtcgca aaagaaacaa
     8821 aaacacctgt cgttgctggc gcagttgatc aagtcaaaga cggcggtcta gcaacagtag
     8881 gaatcgacta cgaaagcttg ggcaaacaaa cagggatcat ggcagcaaaa atcttagacg
     8941 gcaagaatcc aagtgaactt cctgtcgaaa cagcgaatga tttggaactg tatgtcaata
     9001 aagacatggc caaagcatta ggcatcaatc cagacagcat caaagaagct gaataaaaca
     9061 caggaggatt ctcatgacaa atttgctctc tcttttctta tcatctgcat cgcaaggggt
     9121 cttatgggcc ctacttgcga ttggtgtata cgtcactttc cgtatcttgg acattgccga
     9181 cttgactgct gaaggaagct ttcctttagg tgcagggatc gcggcagtaa gtattacaaa
     9241 tggctatcat ccattgacag cttgtcttct aggcttttta gggggtgcgg cagcagggct
     9301 tgtttccgga ctgcttcaca caaaattgaa aattcccgcc cttcttgcag ggatcatcac
     9361 catgactggt ttatattctg tcacatcccg tgtgatgggt gcgccgaaca tctctttatt
     9421 gggtcagcca acgatctttc attgggtcga gtcattcggc ataacaaaag acaacgctgt
     9481 actgatcgtc ggtctgcttt ttgctttgat cgttgtatgt ttacttgttt tgttcttacg
     9541 tacagaaaca ggacttgcta ttcgtgcaac tggcgataat ctggcaatga gcgaagcaaa
     9601 cgggatcaac acagataata tgaagatcat cggttatatg atttctaatg gatgcattgc
     9661 tctttctggc tccttacttg cgcaaaacaa cggctttgct gatttaaatt ctggtattgg
     9721 aacgatcgta attggacttg cttctattat catcgcagaa gttttgttac gtaaccagcc
     9781 actatttctc cgtctcttga ctgtcgtttt aggtgcggtc atttatcgtt ttattttagc
     9841 gttagtcttc gaactgaatg ttgaaccaag tgattcgaaa cttgcttctg ctttcgtgct
     9901 agtgatctgt ctttctttcc cgcagatcca gcaaaaattc catttacctc aaaaaaagaa
     9961 aggcggtagt gtcaaatgaa tgacgtctta acattggaaa atctccatca tacctttgaa
    10021 aaaggaacga tcaacgaaaa tcatgtcctg aaaggcatta atctttcctt agatcccggc
    10081 gacttcgtga cgatcatcgg tggaaatggg gctggtaaat ctactttgct gaacagcatc
    10141 gccggtacat tttctgtcga tcagggtcaa attttattga atggaaaaaa tatcacgaaa
    10201 aaatctgttg tcgaacgttc gaaatccatc agtcgcgtat tccaagatcc taaactaggg
    10261 acagccgttc gtttaacggt agaagaaaat cttgctcttg ctatgaaacg aggaaaaaaa
    10321 cgcggcttct tccgtggtgt caaaccacaa gaccgaacat ttttcaaaga ccagctggtt
    10381 cggctaaatt tggggttgga aaatcgttta tcctcagaaa tcggtttgct gtctggagga
    10441 caacgtcaag ctattacgtt attgatggcc acattacagc gtccagaact gatcttatta
    10501 gatgaacaca ctgcagcgct tgaccctgct acttccaaaa cggtgatgga attgacagaa
    10561 aagctgatca ctgagcagaa tctcactgct tttatggtca ctcatgacat ggaagacgcg
    10621 atccgctatg ggagtcgact gatcatgctg catcaaggaa ggatcgtcgt agatatccag
    10681 caagaggaaa aacagcagct cacagtgccc caattattag cgttgttcaa acaaaacagc
    10741 ggcacggcat taaaagacga tcaagtactt ttatcttcat aatcagaaag aggatgggac
    10801 aaaaaatgaa cgcccaccct cttctttttt ctctttcctt ctttcgtttt tgctttatgt
    10861 atcaaccgtt gtttcttcga aaactatttt gttctctcct tcttcctgat agaatggatg
    10921 ggaaaggagc ttgatgccat gacaacgaaa gacaaggtac ttcaattatt gaaaaagaca
    10981 ccagattttc tttccggaga aaagttggca cagcaactgg aagtttcccg gacaagtatt
    11041 tggaaagcca tcaaagaatt ggaaaaggca ggctatcgtt ttgagcacgg gcctacaggg
    11101 tatcgttacc tgccctctga cgtactagat gcaaaagaaa tccagcaaga gctacggtcg
    11161 tttattcctg atttgaaagt acaaacgatg ttgacttctg aatctacgat gaaagatgcc
    11221 aaactggcag cagctcaagg agattctgtt tcgaagttat ttgttgctga tacacaagaa
    11281 caagctcgtg gacgttttgg acggcctttt ttcgctgaac ctggacgagg aatctacatg
    11341 agtctcttgc tccatccaga caaacggttt gatgaattgc ctcaatatac gatcatcgca
    11401 gccagtgcct gtgtgaaagc cattgaatct gtaaccggtc gttctgcttc gatcaaatgg
    11461 gtcaatgata tctacatgga tggaaaaaaa gtctgtggga ttttatctga agcagtcagt
    11521 gatatggaaa gcggcaggat cagtcatatc atcattggga tcgggcttaa tttttctgtt
    11581 cctcaaaatc attttccagc tgatctccaa gaaaaagcca tctctgtctt tcccgacgga
    11641 caagctagtg tcacaaggaa tcagctaatc agcaaaatct ggcaagaatt gttcacttat
    11701 ctttctcacc cagaaaaagc gttggacttc tataaagaaa aatcattcgt attgggaaaa
    11761 accgtgtcgt tcaatcaaaa aggaacgact tatgtcggtc ttgcaaaaga aatcggtgat
    11821 catggcgaac tgatcgtcca aacaaatgaa cagaagatga gtttgtcttc tggcgaaatc
    11881 agtctcacat ctatccgtac gcaataatta tcagatttca caaaaggaca cctgatctca
    11941 tacagtgtcc ttttttctga attctcttca aaagactctc cttattctat cagctgacag
    12001 tttctctatc ctctagaaaa aggtattcta aaaatatcta taaagcatgg tacactttct
    12061 ttaaatgaat caatgcaaaa aacaagagag tcatcagttt acacgatcaa aagagatagc
    12121 aggccgcttc ctttttcaat cttatagata gaccatgggt aacgataaaa acaaaaaaga
    12181 acttgcgact tattttgccg taagttcttt tttagctagt gccttaatct cttaatccca
    12241 acaaacgtct cgcatagatc acctgaccag agtgcatagc agcatcatca ataatagaaa
    12301 cgagacgcat tcctcgtgtg actggtggtg tccagttctc gtcaattact tcatctagct
    12361 cggaaggttc cagccttctt aagtaagaaa tagcaaaatc agcagctcct cgcaagtatc
    12421 ctagcagatc ttctatttga ttagcttgga tctgctttgc ttgttccaga ctatgcttcc
    12481 aatcttgttc gttatctgct atcgtcatcg gaaaccggct ttcccagtct tgactatgcc
    12541 aaattggaga agttcctgct aaatcagcaa tctggaaatc taattctcga gcggtatgcc
    12601 aagccagcca agtcattgat ttgatctgcg gggctctatc ttccactgga aaacgattgg
    12661 cctcctcaat agagacgcct tcaaacaaac gttcaaaccg atcgtatgcc cgatccacac
    12721 tctcgcatag catatctaaa taatccattt attttcctcc tttttattta tcctacttac
    12781 tttttcctaa ttctaggata cctacttata tgttactaca cacccttatt ttttacactt
    12841 taacagtcac catcatcaat agtttggaga ttgaaagaaa aagatagtgt cgaactatca
    12901 attgaacaag aagcaacaat atgaacgttt cattaatatt ctttaaataa acaatgattt
    12961 ttcaaacgaa cagtttaaga ctaggagaaa aagagtataa taggaaaatg tttgaaagga
    13021 aaggaagggg aaaaatgaaa aaaagggcaa gtttactagt cctagttgct ttgttgttca
    13081 atatcttttc gtatggtgtg gccgtttcag cggaaacata cattcctaaa gaccctggga
    13141 atatttataa tgatctaact ggtaactatg gcttgttagg aattgctagt caattccacg
    13201 tatttgctaa aaataagaca actgtgaatg cacatacaga cggaaatata gcaacacatg
    13261 aacttgatgc aaaaaataat tttggtacag agcttcatga aggtttattg aaccaagaaa
    13321 taaattatat acaaaaaact gattctttcg ctaattcttc aggcatacct acaggtagca
    13381 caagaatgaa taaatttgtc gttggcagta acgtggatgt agcacttcaa gatggtcatc
    13441 ctacagtcaa tggatccagg cttgatcact taactccaga tgatttttat aaagatcgtg
    13501 ctgggcatga atatattgat ttcgagcagg aatttgctaa attgaatgta gcagcaaatg
    13561 atcttgcaac gatcactcca gctaaaacat atactgctgc agattttcca gacatgaaca
    13621 atcggacaat cgatttaact gatttatcag ataccgggtt tttattggta aatatcgatg
    13681 cagaagtgtt aacgatgaat acgccacttc aaatcattaa tccaaatgat caagtagttg
    13741 tatttaatgt catcaacagt tcttctgcat tgaacgtaca gtcaccaatc aaatacaatg
    13801 atcgttcaaa tcatgaaaca gaagattttt cggatgcgaa tatctcttgg aattttggaa
    13861 atgagatgac tgatttgaca atcagtgctc cttttcaagg aacaatcctt gcgcctaatg
    13921 ctactatccg cattactcaa aaccaagacg gaacgattat aggaacaaat gtgattttag
    13981 atgcagctac caatcgttgg gatcctaacg aaatatttat cagcgacaat ggtacagata
    14041 cgacagacac aagcgacagt acagatacat ctaccacaag tgatagctca gattcatca
//
LOCUS       DACGMI010000072        14075 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.074, whole genome shotgun sequence.
ACCESSION   DACGMI010000072 DACGMI010000000
VERSION     DACGMI010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.074"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..587)
                     /locus_tag="IXT46_002453"
     CDS             complement(<1..587)
                     /locus_tag="IXT46_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948346.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVF"
     gene            complement(735..1277)
                     /locus_tag="IXT46_002454"
     CDS             complement(735..1277)
                     /locus_tag="IXT46_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAQ4948347.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            1412..1801
                     /locus_tag="IXT46_002455"
     CDS             1412..1801
                     /locus_tag="IXT46_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948348.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1805..2569
                     /locus_tag="IXT46_002456"
     CDS             1805..2569
                     /locus_tag="IXT46_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4948349.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2698..3645
                     /locus_tag="IXT46_002457"
     CDS             2698..3645
                     /locus_tag="IXT46_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4948350.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3775..4515
                     /locus_tag="IXT46_002458"
     CDS             3775..4515
                     /locus_tag="IXT46_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948351.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(4806..5474)
                     /locus_tag="IXT46_002459"
     CDS             complement(4806..5474)
                     /locus_tag="IXT46_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4948352.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            5608..5895
                     /locus_tag="IXT46_002460"
     CDS             5608..5895
                     /locus_tag="IXT46_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948353.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            6311..7849
                     /locus_tag="IXT46_002461"
     CDS             6311..7849
                     /locus_tag="IXT46_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAQ4948354.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            7846..8811
                     /locus_tag="IXT46_002462"
     CDS             7846..8811
                     /locus_tag="IXT46_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4948355.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            8798..10120
                     /locus_tag="IXT46_002463"
     CDS             8798..10120
                     /locus_tag="IXT46_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4948356.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      10183..10287
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10361..11104
                     /locus_tag="IXT46_002464"
     CDS             10361..11104
                     /locus_tag="IXT46_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4948357.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            11119..12111
                     /locus_tag="IXT46_002465"
     CDS             11119..12111
                     /locus_tag="IXT46_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4948358.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            12123..12860
                     /locus_tag="IXT46_002466"
     CDS             12123..12860
                     /locus_tag="IXT46_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4948359.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            12850..13572
                     /locus_tag="IXT46_002467"
     CDS             12850..13572
                     /locus_tag="IXT46_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAQ4948360.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(13656..>14075)
                     /locus_tag="IXT46_002468"
     CDS             complement(13656..>14075)
                     /locus_tag="IXT46_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAQ4948361.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         4714 a         2387 c         2911 g         4063 t
ORIGIN      
        1 ataaatacac ctagactgac gatgaagagc atatccaaca gatttcctgc gacttggatc
       61 gtcgaagggt tggtcagtgg cattaaagca aggacaaaaa aggaaaacaa gctgtaaata
      121 aaacaggtga caggaactaa tcgaaagaag agcggacatt tcaattggct aaaaatgagt
      181 gaaaaaataa aataagtaaa aatggataaa atcacgacta aaccattcat gataaagaag
      241 aaaagcgtat tgtgattaaa cgaataaaaa agaattgcta aaaaagaaaa cgttttaaat
      301 gcaatcaata cgcttgaagc ttcgtttaac gtaccaggat gtcgatgaaa aaaataggca
      361 ccgaaataaa cagaaaacag taagccgcaa agagaagaca aaatcaaaaa aaacggattt
      421 tcttcggctt ctgtgatatc agaatgatcc aaaagcaacc agcctaatgc actagaaggc
      481 gcatgtgagg tcttaaggta tgaataacat agaaaaaata agatcgtcaa agttgcaaaa
      541 aaagagccta aatgtaaaaa attagtggtt ctacgttgaa tttccataat atctccaaat
      601 taaattgata agtatataaa gtataataac aaattgatga gtatatgtcg atgtttttta
      661 atcaaaataa taaataaaaa ctgtctaaca tttaaaattt aatttagata ttagacagtt
      721 tttaagtttg tgagttattt tccttgtcgt tttctcactt ttttagtcca gaaaccacct
      781 gaaatatatt ttggctcata agaaatgata aaagcacgct cttcgatttc tttgatcagg
      841 cgatacagtt cacgttcgct ttttctagga gaaagtattt cgagaactag ccgctcacct
      901 tccagcccca ttgcagaagt ctgtgtcaca ccataaccgt gttctctcag tatacccggc
      961 aaacttttat cttctgcgct atttgctggc aaaatcgttg tgaccatgat gtatcctaat
     1021 gccaatttgt cttcaatcaa aattccgaca ctgataccta ctgcgtaacc taacgcatag
     1081 acaaataaat tcagtggatt atctaaacga tctaaaacaa gggataagcc gacgatataa
     1141 atcgtgatct cgaccatact gacaagtgga gcaatcagtc gatagccttt cattgtcaac
     1201 atgaaacgta acgtgttcag agtgatataa gcaaaattaa tgaggaagat catccccaac
     1261 atttttggat caatcatttg taaaactcct ttcatttata taacaacaat atcaaaaaaa
     1321 atcgtaagtg aagaaaaatt gaaactttat acatacaaaa aaatgataaa atgattataa
     1381 tagaattata aagataggtt aggtgattaa aatgaaaacg gtcaatcgtg tgttttgtgc
     1441 cagccacgtg ctaagtctcc ttctcagtat atacttaggt gtctattcga ttcaacagcc
     1501 aattgaggta gagaacattg tttttcagat gtcgctgaca gatggtttaa ttttaagcgt
     1561 ttttttcttt ttgatactgt ttattggtaa tattttcggt agcgttgcca gttttttgaa
     1621 tttttctatt tatccactcc tttcgctagc attaggagtg gtgggacttt gttctctgtg
     1681 cttatttccc gagccattca gtcctgcatt tatattattt ggtacactga acctgttcca
     1741 gacaactgtt ggagcatggt tgctatggcg atcaggaaat ttaatgaaaa taggtgagta
     1801 acaattgaat ccaattatat tgaaacgttc tgtccatcat attccagtgt tagaagttgt
     1861 tctgaaagaa ttaagagagg aacgtattcc cgttgtcatc tattatcacg gatggcagac
     1921 aagtaaggag ttagttttga cgcaaggaag aaaaattgcg cagcagggca ttcgtgtgat
     1981 cctgccagat gcgatgaatc atggggagcg caaacagccg gtttcttcta ttccatccta
     2041 tacattttgg gatagtatct acggaaatct gtttgaattt gacacactta tcaagcattt
     2101 agaaaaaaga ggtcttctac atgatcagct tgcagttggc ggggtttcga tggggggaat
     2161 gacaacatgc gccttgttgg ctaaacatcc tcatatagta gcgggcgtgt gtttgatggg
     2221 ttcccctgca cctttggaat atggaaaaga aatcgtaagg cgcgcatcgg aatataatta
     2281 tgtcgtacca aaagactatt ttgatttgat ttcatgggtt aagagctatg atttgtcatt
     2341 gcagccggaa aagttagctg gacgtcctct gttcttttgg catggacaag ctgacgaaaa
     2401 aatcccttat atacaaacgg aacgatttgt agaaaaaaat cggcataagt cttacggaaa
     2461 agaaattgtt tttcgttcct caaaaacaca gcgacatatg gtacaaatac cactaatgga
     2521 agaagcttcc acttttttag caaaaaattt gataaaaaag tataaataat tgaaacggaa
     2581 aatcactcat gacgatagag gattttccgt tttttatttt gggctataat aaactctgtt
     2641 aggaaaattt ggtataattg atagtaagaa tgacaacatg ttagaaagga agagagcatg
     2701 cccactttag cagatgttgc aaaacgtgcc aatgtttcaa aaatgacggt ctctcgagtc
     2761 atcaatcatc cggaacaggt gactgacgaa ttgaaagagt tagttttctc agcaatggct
     2821 gaactggatt accgtccaaa tattgctgca aaagcacttg tcacgaatcg gtcgcagatc
     2881 atcaaattat ttatactgga agaaatcgac acaactgagc cctattacat gaatttgctg
     2941 atgggaatcg ctaaacggat cggtaaagcg cattattctc tccaattagt tacaaatgat
     3001 gccttcgacg tcggttcttg tgatggatac atcatcacag gtgtcagaaa aaaagacttc
     3061 gattggatcg accgtttgga aaaaccagtt gtcttgtttg gggaaaattc tgaaggatat
     3121 gattatgtag acagcgataa tgaatatggt acagcaaaag caacgcaata tgccttagaa
     3181 agagattatc aaacgattat ttatatcggt atcgaagtgg acgagccttt tgaaatttca
     3241 agggaaactg gttatttatc tgtgatgaag gaagttgatc ttcctagtaa aatcttgcgg
     3301 tttccaaatc attcgacaga agtagaaaga tatatgacag aaaactgggc agattttaca
     3361 gataaaactt gttttgtatg tagttcagat cggctagcac taggagcagt aagagggatt
     3421 ataaatgctg gaggacactt gcccgaagaa tttggtgtga ttggatttga tggggtattt
     3481 ttagaccaaa tcagttcacc taaattgaca acgatcaagc aagatattat acgtatgggt
     3541 gaagtatgtg gagaaatgtt gttaaaaaaa atagaagaaa aaggggcgag tcaaggttat
     3601 cgtcgttttt ttcctgaact agttatcaga gagacaacga attaagtctt attactatat
     3661 atatatttat gaaattcatc gctattttct taaaataatc agcgcattgc tactgaaaac
     3721 aatgaatctg tgctattatt gagaaaagtt ccatttttga gaaggatggt ttgaatgaaa
     3781 gaaatcagac gaaaacattt ccgttttcct gcgtacgatg atgagttagg cgtaaaatta
     3841 accaacgaca agaagcgagt attatttgac ggacaagaag atcttttgac tgaacagaat
     3901 cagtccccgt ttgaacagat gaaagaattt catttcacga acacgaacac cgagaaaatc
     3961 cgtcgcaagc gtcgtgcaac aaatggattg aagtcagctc cgcgtaagga aaatttggaa
     4021 aagcataaag gaaaattacc ggattatacc ggccattacc aatcagaaat cacatcgaca
     4081 ggacgaaaaa aactttttgg tgattcctct cgttctgtca gacaaagtga aacaaggaca
     4141 gagtccaagc atactacacg aaacgcatct gttgacacga aggtgcggga gcgttcttat
     4201 tttgttccta aatatgtacc cgcatcgatt atcccagacc ctagagaaag caaaatttct
     4261 gaggatcatt taatcgaatc gatgaaaaaa acggatgact cttatctgtt gttcgataca
     4321 gaaccgacgc cgtatcaaga aaaaagaaat ggtgagccgt ctgtacgaac attcaatcga
     4381 acaaaaacgt tagaggaaac aaagcagtca gaagaaaaaa aatcgaaaaa aagccatggt
     4441 atcttagaac gctcattaca aggattgatc gatgatcaag gaaactcttt gggagaaaat
     4501 agctatttta aataagtgat atacaaattt atattcggct acagttggaa aggaaacgct
     4561 gcggcgtttc cttattttat actctatccg aaagtttata tcgtatcctc aaattttttt
     4621 gagtttaagc gaattttttc tcccaataag taagaaaata atggcaaaat aaaaaaacaa
     4681 actattttcg cagatcgttt gcaaaaatag tttatttttt tataaagaag attttactga
     4741 ataatatcat tttagtttac ataatgatat ttctgtaaat taaataaagt agtgaaaaat
     4801 aagaatcagt gctctaactg ttcaagagga tcaagtggtt caaatgtttc tgtagtctgt
     4861 tttgcttcca attggggcaa aacagatcca atttccagat acttcacttt attcaatgta
     4921 taagatagaa tagaacagct aagtaatgta tacagaaaat gtgtgagatc caaataaagc
     4981 aaggagacaa ctaaaatacc aaaagtaatc aagaaaagac ttttgccaat cttaatatga
     5041 aaatattttt caatggcttg ataaatgata tctgttccgc ctgtgcttcc gccgaatcga
     5101 aagacgagac cgcaaccaat gccagaaaga atacctgtca tcaaactatt gatcagtaga
     5161 ctatctacag caaaatgtat atgaaggctc tcccataaat gtaaaaagaa aactagcgca
     5221 aatgttccga cgatcgtccg gagaaaagcg tgttttccaa aaagaaacaa tgagataagc
     5281 aataaaggta aattaaaaag cagtgaagtg acagaaggag cgaatccaaa aagattatgc
     5341 aaaagcaaag caataccagt aaccccacca tctgccagct tagatggaat attgattcct
     5401 gtcacagcta atccgtagat tcctgcgcct aaaatgattc cgcacaattc tgtaaataaa
     5461 tttaattttt tcatttctag cctcttttct tttgaaaatt ttcagcaact tctttattat
     5521 actgacttat actcttactt caagaggaaa atgaaaaaaa attatttttg gctgtttctt
     5581 tttatttatc aaataaggag tggaaaaatg cgagcagcag acttattgac aattcttaca
     5641 aaatcaccca aaaaaacaga gtatcaagga gtttttttgg ctcaagaaca aaaactggtg
     5701 cctgtgacaa tggtccagat aaataaagca aatcaattta tctttttatt tgaacacggc
     5761 aaagcaccac ttgctatgaa agacatcttt ctttttttga tgaagaaccg tgagaaagct
     5821 gtttattatc agtcaaaaga agaactcatt cctctttatg gagtgaaaga gatagaaaat
     5881 aaagtggtga tataagtaaa aataagaaaa caagacgttt atgatgtcaa aacaaccatt
     5941 ttttacattt ttggcaaaaa agtgtcatga tacagtataa tattcgttga acaggccaat
     6001 aaaggtgttc tcccccacga gatttctact ttattggctg tttcttttta ttaaaataaa
     6061 agttgtgtgt gtaaaaaaga tatagctgat tccaagtgac aatttcgtat agatttttat
     6121 ggtattcgta gtgaaaaaac gagaaccaaa aagttgatcc gactttgttg cttggattct
     6181 ttttttgtca gcatatttag aggtattttt ttcttttttt tgttcgtgct gtaaggttaa
     6241 ggcaagacaa gttagttggg aaaaaggaaa gaaatgttta tacttaaaga ataacagaaa
     6301 ggaaggtcgc atgaataatt ttatacaaac attaagtgaa agaaaaggcg agttgctgga
     6361 agctgcattt caacatctgt ccatttctct catttctttg ctgattgcag cactgattgc
     6421 tattccttta gcgatttggg cagccaatca taaaaaaatg gcagaagtct tattgcagat
     6481 cacgggtgtg ctccaaacga ttccttcact tgccttatta ggtttactta tcccatttgt
     6541 agggatcgga actgttccag cattgattgc acttgttatt tacgctttgc ttccgatttt
     6601 ccaaaacacg tatattggtc tagctgaaat tgacccgtct attgaagaag cagcggtagc
     6661 atttggtatg tccagaatga gacgcttgct gaaagtagag cttcccatcg cattacctgt
     6721 cattatctca ggtatccgaa ctgccttagt tttaatcatc ggtacggcta ctttggcagc
     6781 attgatcgga gcaggtggat tagggacatt tattttgtta ggtattgacc gaaatacacc
     6841 tgttttgaca ttgattggtg cgatcagttc tgccttgctt gcaattatat tcagcggact
     6901 gattcgctgg ttgcagcata agaaacctcg atattccatc attactttag cagcagtggt
     6961 gtgtttattt ggcggcgttt ctttatatca gtctgccttg tttaaaaatg aaaccatcac
     7021 gattgctgga aaattaggag cggaacctga aatcctgatc caaatgtata aagaattgat
     7081 tgaagacaac acaaaaacag aagttgaatt aaaaccgaat tttggcaaga cgagtttttt
     7141 gttcaatgca ctggatcaag gtcaaatcga tatctatcct gagttcacag gtactgtcct
     7201 agaaagcttg gtgaaggtac ctgaagcaat gaaaagtgct gatttgacaa aagaaaaaac
     7261 atatgacgaa gcagaagaat tattgaataa gcaattcgat atgacattat taaaaccaat
     7321 ggcttaccaa aatacgtatg ccttggcagt caagagatct tttgcgaacg aacatcaact
     7381 taaaaagatt tccgatttgg cagctatctc tgatcagatc aaagcgggat tcacactgga
     7441 atttattgat cgttcagatg gatataaagg aatccaagaa gcatatggct tgaatttttc
     7501 aagtgtacaa agcatggagc caagtttgcg ttaccaagca atcaataatg gagatgtcaa
     7561 tattgtggat gcctattcca cagatagcca gctcaaggag tacgatctag tgactctaga
     7621 agatgatcga gggttattcc cagcttatca aggcgcaccg ctgatgaaaa aagattttgc
     7681 taaagaacat cctgaaatcg ttaaagcact gaataaatta agcggaaaaa taacagagga
     7741 tcaaatgatt gatatgaatt accaagtcaa tgtcgaaaag aaaaagccga cagaagtagc
     7801 acgaatcttc ctgaaaaatg aaggattagt aaaggaggaa gatcagtgac taaattaatc
     7861 gagttcaaac atgtgcaaaa aaagtatgat ggaaagtatg tcatcgatga cctaaatctg
     7921 gcaatcaaaa aaggagaaat ctttgttttg gttggtcctt ccggtagtgg aaaaacaact
     7981 actttgaaaa tgatcaatgg attatctaaa ccatcagcag gagacatcta cttcaaagga
     8041 aaatcgttaa atgaatataa tctgcagaaa atgcggtgga atatgggata tgtgctgcag
     8101 caaatcgctt tgttcccgac catgacagtc aagcaaaata ttgaagtcat ccctgaaatg
     8161 ttaggttggg aaaagcagaa aagagcagac cgtgtagatg aacttcttca aaaagttggc
     8221 ttatctcctg atatttatcg agatcgtatg cctagagagt tgtctggagg agaacagcaa
     8281 cggatcggga tcatccgagc tattgctgca agcccagatg tgattttgat ggacgagcca
     8341 tttagcgcat tagatccgat ttcaagaaac tcattacaag aattggtttt gtccttacac
     8401 gaagaattgg gcacgaccat cgttttcgtt acgcacaata tggaagaagc aatcaagcta
     8461 ggtgatcgta ttgcatttat gaaggatgga gaaattatcc aatgtgacac accagagcag
     8521 ttattgatga atcctaaaaa cgactacgtt cggcatttct ttgatgaacc gaaacagacg
     8581 aaagagtggc gagtagaaga tttagtcgtc aatggatatt tcttaaatga aataccagaa
     8641 aatgctcgtc aacaagtttg ctttgatacg cctatgaaag aagtatattc gcttctttcg
     8701 gtgtatccaa gcattgtgat agtagaaaag caaagaagta ttgggtcgct gacaagtaaa
     8761 gaaatctttg cttttttaag tcgagaggag gaaggaaatg aaaacatatg atgcaatcat
     8821 catcggttca ggtgtgagcg gcttaagtgc tgcttatgga ttgaaagaag caggtaaaac
     8881 agtactagtg gtcgaagaag atctatgggg cgggacttgt cctaaccgtg gatgtgatcc
     8941 taaaaaagtc ttgttaagtg cagtagaggc acgtaatcgg gtaaaacaat tgagtggaaa
     9001 aggttttaac gagatcccaa ctgccaactg ggaagaactt caaaaattca aacgaacatt
     9061 tacggatcca gtcccagaaa gccgaaaaaa acaattagca gaagctgaaa tcgatcatct
     9121 ttcaggaacc gctcgttttt tggatgattc atctattgaa gtcaacgaag aagtcttcca
     9181 tgcggattac ttagttttgg caaccgggca aagacctacg atcttaccag tggagggaaa
     9241 ggaatacttg aaaactagtg cagacttttt atcattgcct gtactgccta aagaaatcat
     9301 ttttatcggt ggtggttata ttgcttttga gctagctacg attgccaatg ctgcagggag
     9361 caaagtaacc attgtccatc ataatcaacg gccattaaaa gaatttgagg cgtctttggt
     9421 agaggaagcc gtccatcaaa tggaagcatc tggcattcag tttgcttttg gtgttgaaac
     9481 ccaaaagatc atttcagaag gtactcgcta tcgtttagtc ggaaaagaga cggaattagt
     9541 agcagatatg attttttgtg cgactgggag acagccgaat acagaatctt tagcacttga
     9601 gcaagcgaat atcgtctttg ataaacacgg aattgcagtc aatgattatc tgcaaacgag
     9661 caatccaaaa atttttgcgt gtggagatat tgtttcaagg aaaaccccaa aattgacacc
     9721 agtcgccact tttgaaggaa attatgtagc taagcggata acggatgcaa caagcgaacc
     9781 tatcaaatat ccgattatac ctacgatcgt ctacgccagt cctaaacttg ctgaagtagg
     9841 agttacaaaa agtcacgcct cttcgtcaga tcaagtggta gagatggatc ttaccagttg
     9901 gttcacctat catcgtgtca atgaaccagt tgctaaggct gaattgacct ttgaccagca
     9961 aaattatttg attggtgctg cagtgattag cgagcaagca gacgaattga tcgatgattt
    10021 gacactcgtc atcaatcaaa aattgactaa aaaagagttg gatagctata tcatggggta
    10081 tccgacattg gcaagtgatc tctcctattt attgaaataa tcagcatgat aactaaagcg
    10141 cttgttgctt tttccttctt gtgctacact ttaaaaaatg aatacctgtt tctggggatg
    10201 tcgtagacga catgagagta agttgtgaac ttagacccat tgaacctgtc agttaatact
    10261 ggtgaaggga gaaacatagc agacgcttga agcgggttac tatgtcgtgc ccatttcaag
    10321 cgttttttgt tattcatatt agaagaaagg aggtaacaaa atgaagaaaa atctttatcc
    10381 agcagtcagt atggcattca ttttaattat ttggcagatt gttgtcatag tttggaaaat
    10441 acctgccttt attttacccg gacctgctgc tgtattttct gcattagcgg cagatgcaca
    10501 agtattactt tcccattctg tcacgacatt aaatgaagca gtgcttggtt tggtaatagc
    10561 tagcgttctt tcttttatta ctgccttggc aatggattat tggaagtttt tagaaatgtc
    10621 tttttatccg ttactagtga tttcacaaat gttgccaatc atggtgttag ggccattact
    10681 taccctatgg tttggtttcg gtatgcttcc aaaagtgatc cttgttgtct tgataagcta
    10741 ttttccgatc gtagtttctt tttcggatac attgaggaaa gtatcaaaag agcaaatcat
    10801 ctttttgaaa acgatggggg cagatacagg gaagatttat cgaatatata aaataccagc
    10861 gggtttatcc ggcttctttt ccggtttaaa agtggctgct acttattgtg tcagcggagc
    10921 agtcgttgga gaatggctaa gcgctcaagc aggcttaggg tattacatga tacgcgtaaa
    10981 aaacagctac cagatcgata aagtttttgc tgcgatcatt tgtgtcattc tattgagttt
    11041 attgctgaat ggcgcttgtt cattattgaa aaaagggtat tatcgtatgc tttatatttt
    11101 ttaagagaag gggatcaaat gaaaaaatta tggcttttat taccgctact gttgctttta
    11161 tccgcttgtg gcactgcaaa agaaacaagt agcaaacaag aaataaagga tttgaaaaaa
    11221 gtgacacttg ttttggatta tgtaccgaat actaatcata ctggcatcta cctagcaaaa
    11281 gaaaaaggct attataaaga ggctggttta aatgtccaaa tcatcgaacc aggagataat
    11341 tcgacaagta ttggtctagt aggtgcggac aaagcacaat ttggtgtaag ttatcaagaa
    11401 gatgtcactt atgctcacgc agatggacag aatataccag tcaaagcaat tgctacagtg
    11461 atcaaacata atacttctgg attcgccacc ctatcagaca gtaacatcca ttcaccaaaa
    11521 gattttgaag gaaaaacata tgcaggttgg caaagtccaa gtgaagaagc tgtcttaaaa
    11581 gctgtgatgg aaaaagacgg cggggacttt tcaaaactga caatggtagg aagcaatgga
    11641 gaagggccag aaagcttagg aaaatcctca gatatccaat ggtactttga aggttgggat
    11701 atgatcaaag caaaagaagc gggtattgaa ctaaactata tcccattgaa agaattagat
    11761 gaacggttag attactatac tccggtaatt attacgaatg atcaactgat caaaagtgat
    11821 ccagaattgg tacagtcttt tatggatgcc acgaaaaaag gctatcagga agctattaag
    11881 gatccaaatg acagtgctaa actgttgcaa aaatatgcaa aagaaaatga tcggacgttt
    11941 ttagaagaat cacaagcatt cttgtcaaaa aattatacgg atgatcctga gaattgggga
    12001 ttgatggaag aaaaagtttg gcgcaattat acagctttta tgcaggaaaa cggattgatc
    12061 aagcaagatg taccttcgca agaactattc actaatcagt ttataaaata ggagtgatag
    12121 atatgtcaat ccaaatcagc cacttgaatg tagtcattga aaacctgaaa atattagaag
    12181 acatccattt cactatccct aaagatacct ttacatcgat tgtcgcgcca agcggagccg
    12241 gtaagtcaac attgctgaaa actttaacag gagtccagcc tatgacttct ggaacgatca
    12301 aagtagacga tcaaaaagta actggtctcc atacagcatt tagttatatg ccgcaagaag
    12361 atatgttact tccttggctg agcgtctatc aaaacgttac gttatatcaa aaaatcaatc
    12421 atctaacaat caatgaagaa caagtaaggg attatctgga tatctttggg ttaaacggct
    12481 atgaacattt tttgccggaa caattatctg gcgggatgaa gcagcgaacg gccttgttac
    12541 gaacaatcat gaatccttct tcttacttgc ttcttgatga accatttgga gcgttagatg
    12601 ctatgaccag agggcagatg caagactgga tgttgaagct gcctaaaaaa gcaaagcgga
    12661 ctactttact tgtgacgcat gatatcgaag aagcaattta tttatcagac aggattcttg
    12721 tgctttccgc ccgtccggca catgtgattg ctgagattca agtgcctgaa aaacgacggt
    12781 cacgtgaatg gctactgcag caatcagagt tgaagcaaac gatttatcag ttattggcag
    12841 gtgaattaga tgttaagtga tgctcattgt catttagatg ggagtcagag tttagcactc
    12901 cttcagcagg aacacacgat tttgacgatc atcaattgtg attcgccaga agaatggaag
    12961 gaaaacagac agcttgcagc aagtaagact caagccttaa gttacggtat ccatccttgg
    13021 aaagcagata gctatacgtt tgaacaagtt gagccttttt tgaaaaaagc aaggatcatc
    13081 ggtgaaatag ggttagataa tatttggacg aatgtaccga tgactacaca aaaaaaagta
    13141 tttgagcgac agcttgcttt tgcagccata aatgagaaac ctgttgtact gcacacaaaa
    13201 ggatgcgaaa aagagatctt aaattatatc caagcttacc ctaatcacta tttgatccat
    13261 tggtattctt ctttggacta tcaacaagac tatattgatt taggctgtta tttcagcatt
    13321 ggtcttgatt tgaaaaagaa tccagcagtc tggcaactag ctaaagcagt cccaatcgac
    13381 cacttactta ttgaaacgga tggactacat gcagcagagt gggctttagg ggggattttt
    13441 tcagaaaaag attatgtctc actgcttgaa gaacagttaa agacaatcgc tgagatcaaa
    13501 gagctatcag ttgaagaagt taaaaaaaat acttatcaaa acttggaacg tttcattaga
    13561 ttaggtaaat aaaaaagaga tgtgacacaa ctagtgtcgc acctcttttt ggctttcttt
    13621 gtataaaagt aaactgtttg attaataaat gaatcttagt accaaccgtt tgcttcccag
    13681 aatgctttcg ccgcttccca agaaccataa cgtgaagtaa catattgttc tgctactctt
    13741 tcttggtttg cagcagagta gtcaccattt aagtaagaag aatctaattg gtaacgtccg
    13801 atgtaacgtc cgttcgttgc tgtgtaagaa ccgcttgatt ctttttgtgc gatccattct
    13861 tttgcagagc ttgtgcttgc tggagtagca gcagtttctg ttacagcagg agcaggttgt
    13921 gtttcagcaa caggcgctgc ttgtttttcc gtttgaaccg tttcttgtac aacaggttgt
    13981 tcagcttgga ctggtgcttc ttgaacggct gcttgaggtt cagcagctgc ttgtgcagag
    14041 ccttctgttg ggattgttaa ttgttgtcct gagta
//
LOCUS       DACGMI010000073        13949 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.075, whole genome shotgun sequence.
ACCESSION   DACGMI010000073 DACGMI010000000
VERSION     DACGMI010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.075"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            949..1422
                     /locus_tag="IXT46_002469"
     CDS             949..1422
                     /locus_tag="IXT46_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAQ4948362.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="IXT46_002470"
     CDS             1431..1658
                     /locus_tag="IXT46_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4948363.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2294..2665
                     /locus_tag="IXT46_002471"
     CDS             2294..2665
                     /locus_tag="IXT46_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948364.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2921..3163)
                     /locus_tag="IXT46_002472"
     CDS             complement(2921..3163)
                     /locus_tag="IXT46_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4948365.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3195..4097)
                     /locus_tag="IXT46_002473"
     CDS             complement(3195..4097)
                     /locus_tag="IXT46_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4948366.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4110..4298)
                     /locus_tag="IXT46_002474"
     CDS             complement(4110..4298)
                     /locus_tag="IXT46_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAQ4948367.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="IXT46_002475"
     CDS             complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="IXT46_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAQ4948368.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4913..5806)
                     /locus_tag="IXT46_002476"
     CDS             complement(4913..5806)
                     /locus_tag="IXT46_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4948369.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5884..6822)
                     /locus_tag="IXT46_002477"
     CDS             complement(5884..6822)
                     /locus_tag="IXT46_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAQ4948370.1"
                     /translation="MRYYFVDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPD
                     DIFVGTEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLI
                     TCIDRKTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAAR
                     KTTENEELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQ
                     RQTEKMIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTG
                     GLPGKSSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6856..7206)
                     /locus_tag="IXT46_002478"
     CDS             complement(6856..7206)
                     /locus_tag="IXT46_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAQ4948371.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7239..8141)
                     /locus_tag="IXT46_002479"
     CDS             complement(7239..8141)
                     /locus_tag="IXT46_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAQ4948372.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8134..8991)
                     /locus_tag="IXT46_002480"
     CDS             complement(8134..8991)
                     /locus_tag="IXT46_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAQ4948373.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9325..10134
                     /locus_tag="IXT46_002481"
     CDS             9325..10134
                     /locus_tag="IXT46_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4948374.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10174..10671
                     /locus_tag="IXT46_002482"
     CDS             10174..10671
                     /locus_tag="IXT46_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4948375.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11056..11129)
                     /locus_tag="IXT46_002483"
     tRNA            complement(11056..11129)
                     /locus_tag="IXT46_002483"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11093..11095),aa:Ile,seq:cat)
     gene            11316..11639
                     /locus_tag="IXT46_002484"
     CDS             11316..11639
                     /locus_tag="IXT46_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948376.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11803..12057
                     /locus_tag="IXT46_002485"
     CDS             11803..12057
                     /locus_tag="IXT46_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948377.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12127..12372
                     /locus_tag="IXT46_002486"
     CDS             12127..12372
                     /locus_tag="IXT46_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4948378.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12448..12813
                     /locus_tag="IXT46_002487"
     CDS             12448..12813
                     /locus_tag="IXT46_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948379.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12874..13437)
                     /locus_tag="IXT46_002488"
     CDS             complement(12874..13437)
                     /locus_tag="IXT46_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948380.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         4090 a         2577 c         2303 g         4979 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaata atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca
     1801 tacaaagggg gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct
     1861 gttacgttgt agttggatct gcttttagta taatacttta ttcattccac cagactgata
     1921 gcagtttgag cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga
     1981 agtgcttaaa acttcagcta atggcccatt gtgttaactc ttactccatt cttttttagt
     2041 aagctcccat atatactgta aagccttcta tatattatgt catgttgctt tttaacattt
     2101 actatgtagt tttgataaaa tgatttgaat aacagtgatg gacaattctt ttttattttt
     2161 aacattattt tgataataat gattatttat ttaaaaatac attagataac atttgttacg
     2221 acacgaaaaa gcttcacaaa caaatatcgt tattttaaaa tgagggcgaa ctcacacaat
     2281 taggaggaat agtatgccat ttattgttta cttttttctt tcattactcg tgatctatat
     2341 tccattacca acatttttcc tgctcgtcaa tcgtctagca gagcaacatg atacgattgc
     2401 tgctcttacg aaactttgtt tacttctatt tgtttgtcta gattacttta cgagctatta
     2461 ttggctaaaa cagacaagag taaaaaagag atattatttc ttccttgtct ttttcaatct
     2521 ctttgagttt ctgatccatt gctttttact tcatcagtat catacgatcc atttgtggat
     2581 catctgggtt ttcaaagtgg tcgtattatt ttgtatgttc acctttccta tctcaagaaa
     2641 atttagggag gcattgtttt attaaagaag cttctctgta tcaataaaga cacatttaag
     2701 gaaaaacttt taaaaatcta attgggaatt tgcccgcata aataagaggc tgtgacaaaa
     2761 gtcttgtcac agcctcttat tccgtataaa cagtgttcaa aagcttgcat cttcgataat
     2821 atgcccaacc aaatgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga
     2881 tgaagaacag ctttttcacg acctcttttt aaaagtcttt ttacagtttt cgagcaaaga
     2941 atgatacgat tagtactaaa atgatggcac caatcaatga tggcacgatt gccattcctg
     3001 caatacttgg tccccaagaa cctaataatg cttgaccaag tgctgatcca actaaacctg
     3061 ctacgacatt tgcaataatc cccatcgaag aacctttatt cgtgattgct cctgcaattg
     3121 ctccgataat tcctccgacg ataagtgacc aaataaatcc catgtttcgt tcctcctaat
     3181 gttttacttc cttattactg aacccgtggt tctgtatttt cttttacttt ttgtgcgccg
     3241 cttccagctg ctgattttac tttatctgtt tgattcgaag caaattcacc ggtttttttc
     3301 gctgcgtcag ttactttgtc ttgcaccgtt tcttgatctt tttcaaattc ttcttttgtt
     3361 ttgatgtcca ctacgttagc gttgacttcg atcacttcta aatgtgtcat attttttact
     3421 tctttgccga ttacttcttg catttcttca aagatttttt cgatatcttt gccatattcc
     3481 acaatgacat ccatatcaac tgctacttgt tttttaccga cttctgtttc gatcccagcc
     3541 gttacattat ctgtattcac aagttttcct gccacattag agaagaaacc accgtttgca
     3601 gataataaac cgtctacttg ttcaattgcg attccgatga ttttttgcac aactttatct
     3661 tcataattca gctcaccgcg cattgaatct tcctgttcag aatcatgctt tccttggtta
     3721 tttgtatgat cagaaccaag ttttccttgt ccgtttgtgt ggtcagaact aagtttttct
     3781 tgtgctttcg catggtcaga aggatgtttt tgctcttcca caggtttaga aggatcgatt
     3841 gcatcatgtt gttctggaac tttagattct ggagttcctg gatgatgagg tgcatgcttt
     3901 tctgcatcat gtttcttctc ttctactcct tgttgaacgt tagggactac tggatctgga
     3961 tgtgcagata ctggtgctgt tttgttcttt tcatcgttca caccatttga ttggtttggt
     4021 gtcgttgggt ctggatgtgc agacactggt ttttggttgt tcattttatt gttattattt
     4081 ttgttattgt tattcatgga tgtttcctcc taagatttaa aatagtgatc taagattttc
     4141 gtttgtttca gataaaaacc gatagcgacg ccgatcgctg ccatgatcaa gatcaataag
     4201 gtcttgaaaa agcccacggt gatccataaa acggctaata tcaatccaag taccccaaag
     4261 atgataggga gcttgtatgt cgaaaatagt tctttcattt ttggtccccc cctattctac
     4321 tcgtttgcgg tcattgcttc gtttagctgg ttcttcaaag cctgtgtatt tcaccgatac
     4381 tttcactggc tcttttgttc ccaatatgtg ttgtacttca ttttcgattt ctttcatcaa
     4441 tgttcctgtt ttaccaatga gtgctgaagt tcgtttcaac tcccctttta cattgacggc
     4501 gatcttgttt ttcgttgctt tgacatttac ttttggtgaa tggatgaatt catcttcatg
     4561 caagtgagaa cgaaccattc cttcaattgc ttttttatcc aacgtcaact ccccatcacc
     4621 atgtttcagt agaaagtttc cgattgtttt tggataaaac aggaaaacaa gtaacgtgat
     4681 aattgtcaaa atagcaaatg caacggcaag ccaaaataca tattgttgca cgtatgaatt
     4741 agtgatggaa aagaatcgaa acttctctag ctgaaaaggc aatggatagg ttgcacttaa
     4801 tagtatcgca aacaaaagca cagatagcaa aagtaatgtt ccgatcactc cgatcgtttt
     4861 tacaccttta ttcattttcg cacctcctca taggggtgaa acgatcaact tcttataagt
     4921 tgatcgcttc tccaccagtt actccgtaaa tttgggctgt aacataactt gctttattcg
     4981 atgctaagaa aacataaact ggtgctaatt ctcctggctg acctgcacgt tctagtaaac
     5041 tttgctgacc aaattcaggg atcgaatcag aaggttgtcc ttcgtctagt tgtaatggtg
     5101 tccagattgg accaggtgct acaccattta cacggattcc tttaggtgca agctgttttg
     5161 ctaaaccgat cgtaaagtta gcgattgaag cttttgttgc tgcgtaatct aataaatgtt
     5221 cgcttggatt gaatgcttga acagaagttg ttgttacgat tgctcctcct gctgggatat
     5281 gcggaacagc ttctttcact aaagcaaaca tagcgatgat gtttatcata aatgtgtctt
     5341 tgacttgctc aagtggtaac tcagcaatag actgacaaga aatttgctgt cctgcgttta
     5401 gtaccatcgt atctagcccg ccaagttcac tcacggcttt atctatgatt tctttaggtg
     5461 cttgttcgtc acgaagatca aaaggtagta agacaatctt acgtcctgca actttcacgt
     5521 attttgctac ttcctctgca tctttttctt ctcctgggaa gaattgaaga gcgatatctg
     5581 ccccttctct agcaaatgca atcgctgctg cacgaccgat ccctgaatct ccaccagtga
     5641 ttagtacacg gcggttttct agttgattat tgccttcata ggattcttct ccacaatcag
     5701 gaacaggaat catattctgc tgtaaagctg gtgtatcctg atcttgttta ggaaatttct
     5761 ccgtatggta caagtttcgc gggtcgatta attttggttc tgtcattgct gtattcctcc
     5821 tagtttttaa attgtattgc caaaacaaat ttctttgttt gatacctgtt ttaaatagat
     5881 tctttaattt gtataatctt tccggtataa atggtaacct aaaactactg ctgctatcaa
     5941 agagccaaag actacgagta taaagcctag agcagaactt ttacccggta atcctcctgt
     6001 attcattccc caaatccctg cgaacaacgc cggaacggaa atgattaatg cagctgaatc
     6061 tagatatttc atgatatgat ttagattatt gtccatcatc ccgttgaata gatcaccaat
     6121 actctctaat aaatctcgat agatctcgat cattttttct gtttgtcgct gtctcaaatg
     6181 gacatcatag agtagctgtt catcgtctaa acgtttgatg aaagtttcag aattccataa
     6241 ttgatccatt gtttcccgtt gatctcttaa ggtatgatcg atatatacga tgtctctttc
     6301 aagatctgcc tgtttataca gttcttcatt ttccgttgtt ttacgagctg ctttatccaa
     6361 agcgtcaatt cgctttttca tctctcttag ttctttcacg taatgggtgt aaatatctaa
     6421 taatgtatac gtgatgatct tttcaaacga gtttaaatga tttccatgct ttgtcagcag
     6481 ccgatccaca aattcggttt ttctatcgat acaagtaatc aagagattat cggaaagtac
     6541 aaaagatatt ggcgttaatt ttttttcgat acgattatct gactgatcta gattaatcac
     6601 taccaaagaa aatggatgct ctagtttcgt ctcataaagg cgctccatcc gagaaacttc
     6661 ttccggatat tcggttccta cgaaaatatc atcaggaagc tcgaattctt cgattgcttg
     6721 ctcaatctct tcgggctttg cactatcaag tacgagccaa ttatattttt tttcatctgt
     6781 ttctattaca ttcttttctt catccacaaa gtagtatctc aatgtatacc tccttttttg
     6841 actttctcga aactattagc tgaagaagca gttctttaat ttgatattat aatcgagtac
     6901 tgcgatttca ttttctaatg aaaagctgtc aagctgtttg ttgaagtcca tgttcaatcg
     6961 tttaccgaaa taattttgct ctaatttaga tgtatagatg tccaataatg gatgctcgat
     7021 tttagtcgca tattctccaa attccgaaac aaaaggaatg atttgaaaaa agctgccttt
     7081 tgcaaaagca cctttgtccc ttagaaatgg atcggaatca ttgataagcg cgagtgcgat
     7141 ttttgtattt tccccaacct tttcaattaa cgtctctact gcatttttag acattgtaat
     7201 ttccattcct actccccctc ttcagttgtt gtcttctatt atttaacaac tacatctgtt
     7261 tttggttgaa cttttgcata ttttggatat ttagggaatt tagctacaca acggaaagcc
     7321 gtcatccctg catatttttc gtaatatttc ttcgttggcc cttcaaaatc cttgctccac
     7381 ggtttcacat gtcctgaaaa atggataatg taaggattgt tgcgagtttc ttcgtattca
     7441 cgttcacctg ctgctgttgg atgttttttt gcttttgcca tgatatagcc ttgtgcattc
     7501 caacgcggat gaagtggtaa ccaacggtca tgtaagatag catttaatgc atcttggtca
     7561 tggaatcgta atttttctgg attatgttcg atgaaatcta atactttttg cgtaatattt
     7621 tcatctaacc attttttcac attgatcagc atcaaacctg agttgaaata acgcattgat
     7681 ttagctgaaa ttttcatttt ttccagtcgt tgatggaacc cagcgtcttc aacagctgct
     7741 acgattgaat caccgaagtc aagacgccat aatttagaga tatcttgtaa agcgatcatg
     7801 tcgcaatcca tatataagat acgttcaact tctgtgccgc ggaacaattc cggaatcgca
     7861 atacgataat aagctgtttc tggaatacga tcgctgatta ccacatttgt aaagaattct
     7921 ttattgattt tcaagaattc cacatctgag ttcattcgtg cgtttttcac tgagaagcgt
     7981 aaaagctgtt tactttcaaa atcgatatca tcgtcaatca catagaaccg aacaaattta
     8041 gacgggttgc aattatctaa tactgagaca aataatgcag ctaaatgtgg tacgaatttt
     8101 gtgttacaac ttgcgactac tgctatttct tttttattca ttgatctcgc ctactttcgt
     8161 tagagtactg tgtgctaatt tttttaagta taaattggta tacggatgat ctttcaacgt
     8221 attccaaggt ttatcatgtc ctgtaaagtg aacgatcgaa ggtttttcat ttccttcttt
     8281 atactgacgt tcatattttt catttggtgc tggatgacgt tcaaaaatca gcgaagtctg
     8341 catgttccat tttggatgaa gttgttccca atcttcataa agtacagcat tcaaagcatc
     8401 ttggtcgtga tagatgattc gatcgccatt ttcactgagg taatggatag ttttttctgt
     8461 aatttctttt ttattccatt gatcaatgtc aatcaccatc actcctgaat tgaagtacaa
     8521 gtcatcggaa tcgattccta atctttccaa agctttcact tggcctggat cgataatagc
     8581 gccgattgtt tttccattta acggctcatc atatagtttt acgatatcgt ctagtactaa
     8641 cacatctgaa tctaagtaaa ggactttctt ataatcctct ttagctaata agtttggtaa
     8701 agaaattctt aagtaagcgg tagttgtgat atggtcactg actaggaagt cttcgtagat
     8761 atctttttcc actgtcagga attggatact tgcattactt gaatatttat ttaccgtttc
     8821 ttccaatcct tctttactat attctgatag accatcgtca atcacataaa attttatgcg
     8881 tcttgtttta ttgcaatttt ctaatgcagt tgcgatcatc acgctcaagt aaggagcata
     8941 attttcgtct gaagcagtta ccacaggaac tacgccgtat ctcttctcca tcaaaatcac
     9001 tcctttttct aatctttttc taacctgttc tacatctaga atattcctca tttggtttta
     9061 aagcaaaata tatgctttgt tttcattgaa tattttaaaa tttttttatc acaaaacgca
     9121 tcggtaagcg ctaactattc gtttttcatg gctttttatt caaaggtatt gaccaaaaac
     9181 tactatatat agccaccttt ttcttaagaa tgttttttga aaaaattcat aatgacaaag
     9241 caagttagtt tcattttttt aaattctcat ttaatcttaa ggtaacagga aaatagatat
     9301 gtaaaaagaa agtaggaaga taaaatgaaa ctagcagcga ttgatttaga cggtaccttg
     9361 cttgatcgaa atggaaagat accagaagaa aatatccaag cacttcggaa atttgatgaa
     9421 aatggcggaa tcgtaaccgt cgctaccgga aggaacagca tttctgctaa agatattttt
     9481 tccgaattag gaatcggtgg ctatttgatt tcttccaatg gttcactgat tgctgaaatg
     9541 aaggatggaa aaatggcgaa agttctcaga cgttcaaaaa tagatagcga tacactgaga
     9601 aaagccttct tctatgctca agaagcgaaa atatccatca ttgctagccg agaaacccaa
     9661 gatgatcagc tgacattcga tgaatcaaat ctagtcaaag atgaccctta ttatgaacat
     9721 ttcaatttac agaaccattc ttttgatcaa attttaaata tgttggaaga tccttctctt
     9781 agctatctta aattagcatt aacagataag agtgaagaaa aactacagaa gctacaaaga
     9841 gatctgcaag cagatggtat ccaatcagta ttctctgatc cgcatttctt agaaatcacg
     9901 cctacaggta tcactaaagc tcattcactt gtttttctgg cggattacct tggaatcgaa
     9961 tcgagtgaca tcatggcttt tggcgatcaa gaaaacgaca ttgctatgtt gaattacagc
    10021 gggttgagta ttgcgatggg gaatgcacag cgacaagtaa aagaaattgc aaaccaagta
    10081 acactgacga atgaagaagc tggtgttgct tatattttaa aaaacttcta ttaaaaagaa
    10141 taaaatgacg atatgaatgt aggaggaaag aaaatgttag ttattattga tatgcaaaat
    10201 catattcttg atccaaacag cgaattttat attccagagt cagatcaatt ggcagaacgt
    10261 attgctcaaa gattagctaa agcacgccaa aataatgaat atattctctt cacacgggat
    10321 ataccagttg aactgaagga caaagaagaa gaacgagaag atttgcaatt gatccctctt
    10381 ctttctccac aagaaaatga acgagtgatt aaaaagtatt actttacgat tccacctgaa
    10441 actttagctg aaatccagga aactttattt gaaagcaaag aagaacaaaa agagatcgaa
    10501 gtagtcggga ttgaaacaaa cttgtgtgta ctctctaatc tgataggcct gcagagtgct
    10561 tttcctgaag cagacttttt tgttgatcca atgttagtct ccagtagaaa acacggagaa
    10621 tccgctttag agctgttgaa agatttcaac gtctctatcg tcgaatcata aaaatatcta
    10681 tcttcattta cgatatttaa cacacaataa aaaaagcacg cagaactgtt ttagtcctac
    10741 gtgctttttc tatcaaagta gattggcttt tttatgacac agagtgaaac ggcaggctca
    10801 cgacctcttt cttaaatggt gttcaatcag ctgaccctcg gtattagctt aacaaacggc
    10861 aaaatatgag gaactatttt tccgtttgtt aagctaatac tcaggtcaaa acgctgattt
    10921 cacaacctct tccttaaacg gtattcaaaa gcttgcatct gcagtaataa gaacagccaa
    10981 gtaaaaacat aagaagctgt ttttacttgg ctgttcttat tacttgatgc agggcagctt
    11041 tttcacaacc tcttatgtac cttgtaggac tcgaacctac gaccggacgg ttatgagccg
    11101 tctgctctaa ccaactgagc taaaggtaca tcataaataa aatttatttt tgttactttt
    11161 caactatagc acgaatgaca aactctcaca agtttcaaaa tataagtaaa ataatattgt
    11221 tattcttatt tcttttactt gtgtcataac tattttgtta ctttaatttt tatttgctta
    11281 ttttagaaaa aatgttattc ttttatttat tctcaatgtt aggagtgatt attttgccat
    11341 ttattgcgat tttattcgat ttagttgcgg cagcagctta ttttctccaa ttaaattatc
    11401 aaacctcagg aattctgttt attggaatga tttttcaagg tgtgattacc cttttgcttc
    11461 ttgtcatgat gctcagctat aaaggaaaaa gatatgcccg tattcaaaca aaagtatttg
    11521 ttaaatatgt ttccattcgc tatgggatca tcattctttc ctttttagtg aatgcgatcg
    11581 tcctcttttt atatgtattg aattacttag atatcaatcc attgattttt tctcgataga
    11641 taagacacat tcagcggaac agttcctgct tatcagcaga aaactgttct gctttttcat
    11701 ttttcattga tctattcttc ttttattttc ctagcatttc atttgtgatg tatgcaataa
    11761 catgttatct tttattatat gaatcgttga ggagtccgtt acatgattac gttggtgaga
    11821 gttttgtttt gggtgcctgc ggtcgcactg gtcgcaagta ttgtttatct tatgaattgg
    11881 aacaaagaac ggttttattt agctattttg actcttccgg ctatctactt tatgtggaaa
    11941 gtttttaatt acaactactt tgaacccgat agtgttttta tagaagaatt atcaggactg
    12001 gttttgtctt tattgatcgt cattctttat ttgatacgtt taaataaaaa acattgagta
    12061 ctattgattg catgtgtagc tttctatagt cattataact attctactat aatgaaaggt
    12121 gattaaatga gtatcgaaga agctatttta ctggatactt tacgttgtcg tctgaatttc
    12181 ttaagaactg gccgatcttt atctcaagta gctgtttcta gcgcgttaag tattccttta
    12241 ttcaaatatc gtaagtacga agaaggagaa gaaattccaa gcatcattga attaatctat
    12301 atcgctgact tttacgatat ttccgttgat tacctaattg gtcgctcaga aacagcaagc
    12361 aaactgaagt gattttttcc agccttggtg ctggtttttt catttaacgt ctaaggttaa
    12421 caatctatat ataaaggaga catttctatg cgattatggc atgaaaaatt gatttcaaag
    12481 cttcctcgtc aacagctttt aggacaacat cgggaatgct gtgcattaag aggaaatggc
    12541 tggggaaaga aacatgctac tgtggattat gtttttcact attctcctta tagattattc
    12601 caatatcatc agcttgtcat ggatgaaatg gaaaaacgtg gttacagccc agcaccagag
    12661 tggaaaaatc ctatgtatcg tggcaaatca tgcgaagcat tttttgattt acctactgta
    12721 gagcgcaacg tgccgattta tccggaacac gatgaagttt atctagcaga atgtttagca
    12781 aatttggagc aaaaaggaat ttatcttacc taatataact agaaaagcct tctatctcct
    12841 cttacttcat taaaaagctt taaccatctt agatcaagct aaaatgtcgt aagttttagg
    12901 gttatcttca tcctcacgtg caaaactaaa agcgtactct agttttggtt catcgccaac
    12961 ttccctagac ataaatgaac atctcctgac gtggtttaaa agtaccgcat cttcgacgtc
    13021 tgtatacgat gcacagcaca gattgcttct tttgatcttt cttttgattt ttctgttgct
    13081 tcttctacac cttcttcgat tactacatcg atgcttacaa ttgcttctgc ctaatattcc
    13141 catgcatcgt cgatttaagc ctctgtagtc actgtgatcg tttccacatt ttaactcctc
    13201 tgtcgtggct tcagttgatt ttgtgatcag ttcagttgct aagccagagt cagaacaacc
    13261 tgccattgct agcgttaata ttgatagtaa aaatagtttt tttatcataa ggttcccccc
    13321 ctgaaaatag actaaaataa taacgctttc tttttttgtt ttcagacgaa aattaataat
    13381 ttctaaatat tctttaaaaa agcttataac tattatgcct tttttaatat ataacacagt
    13441 tatttttaaa aataagaatg ctaaatcact ctacaataac ggcgaaagca caaaaaataa
    13501 aaaaattatt acgttattaa aaaaacagat gaaagatcag gttttattag atctcattct
    13561 ttcatcactt gaagggattt aatgaactac tttttcctct ttgtcgtttt tatatattcg
    13621 tattccttca aacagtagga tagcctcttt caatgcttga tatttgaact gtccgttact
    13681 taaaaattta gatgtgccgc cctcttccta gaacatattc ttttttactt tttcattaat
    13741 tgacagacca atcgaacgaa actgtaaatt tcgataggat aatgattggt caaactcatt
    13801 cattttcaag acatctcgat tcatattcaa gataggaatc tttttatcaa catcacttta
    13861 ttcgtatttt cctctaccat aaaagcttca cgctccacaa aattgtttta tacactacta
    13921 ttcagcccat tcaacgacca atgaatttt
//
LOCUS       DACGMI010000074        13917 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.076, whole genome shotgun sequence.
ACCESSION   DACGMI010000074 DACGMI010000000
VERSION     DACGMI010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.076"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            131..505
                     /locus_tag="IXT46_002489"
     CDS             131..505
                     /locus_tag="IXT46_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAQ4948381.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="IXT46_002490"
     CDS             complement(619..1248)
                     /locus_tag="IXT46_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4948382.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="IXT46_002491"
     tRNA            complement(1382..1454)
                     /locus_tag="IXT46_002491"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="IXT46_002492"
     tRNA            1668..1741
                     /locus_tag="IXT46_002492"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            1696..1845
                     /locus_tag="IXT46_002493"
     CDS             1696..1845
                     /locus_tag="IXT46_002493"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948383.1"
                     /translation="MTVNHDVVGSSPTAGVNKAYAKKKKSNHLGFFFFYYYDESSFLF
                     LSRML"
     gene            2338..3666
                     /locus_tag="IXT46_002494"
     CDS             2338..3666
                     /locus_tag="IXT46_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAQ4948384.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="IXT46_002495"
     CDS             3868..4701
                     /locus_tag="IXT46_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAQ4948385.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="IXT46_002496"
     CDS             4717..5454
                     /locus_tag="IXT46_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAQ4948386.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="IXT46_002497"
     CDS             complement(5609..6577)
                     /locus_tag="IXT46_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAQ4948387.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="IXT46_002498"
     CDS             6809..7642
                     /locus_tag="IXT46_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAQ4948388.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="IXT46_002499"
     CDS             7676..8515
                     /locus_tag="IXT46_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4948389.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="IXT46_002500"
     CDS             8541..9101
                     /locus_tag="IXT46_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAQ4948390.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="IXT46_002501"
     CDS             9300..11021
                     /locus_tag="IXT46_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAQ4948391.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="IXT46_002502"
     CDS             11186..12328
                     /locus_tag="IXT46_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAQ4948392.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="IXT46_002503"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="IXT46_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAQ4948393.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4751 a         2298 c         2833 g         4035 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttg
//
LOCUS       DACGMI010000075        13720 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.077, whole genome shotgun sequence.
ACCESSION   DACGMI010000075 DACGMI010000000
VERSION     DACGMI010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.077"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..901)
                     /locus_tag="IXT46_002504"
     CDS             complement(<1..901)
                     /locus_tag="IXT46_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HAQ4948394.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSE"
     regulatory      complement(925..969)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1184..2152
                     /locus_tag="IXT46_002505"
     CDS             1184..2152
                     /locus_tag="IXT46_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4948395.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2265..2543
                     /locus_tag="IXT46_002506"
     CDS             2265..2543
                     /locus_tag="IXT46_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAQ4948396.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2661..2897
                     /gene="secG"
                     /locus_tag="IXT46_002507"
     CDS             2661..2897
                     /gene="secG"
                     /locus_tag="IXT46_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAQ4948397.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3009..3755
                     /locus_tag="IXT46_002508"
     CDS             3009..3755
                     /locus_tag="IXT46_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4948398.1"
                     /translation="MRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSLAEQ
                     QLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3758..6115
                     /gene="rnr"
                     /locus_tag="IXT46_002509"
     CDS             3758..6115
                     /gene="rnr"
                     /locus_tag="IXT46_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAQ4948399.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6137..6601
                     /gene="smpB"
                     /locus_tag="IXT46_002510"
     CDS             6137..6601
                     /gene="smpB"
                     /locus_tag="IXT46_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAQ4948400.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6903..7622
                     /gene="atpB"
                     /locus_tag="IXT46_002511"
     CDS             6903..7622
                     /gene="atpB"
                     /locus_tag="IXT46_002511"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAQ4948401.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7675..7890
                     /gene="atpE"
                     /locus_tag="IXT46_002512"
     CDS             7675..7890
                     /gene="atpE"
                     /locus_tag="IXT46_002512"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAQ4948402.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7981..8505
                     /gene="atpF"
                     /locus_tag="IXT46_002513"
     CDS             7981..8505
                     /gene="atpF"
                     /locus_tag="IXT46_002513"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAQ4948403.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8492..9034
                     /locus_tag="IXT46_002514"
     CDS             8492..9034
                     /locus_tag="IXT46_002514"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAQ4948404.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9057..10613
                     /locus_tag="IXT46_002515"
     CDS             9057..10613
                     /locus_tag="IXT46_002515"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAQ4948405.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            10627..11529
                     /locus_tag="IXT46_002516"
     CDS             10627..11529
                     /locus_tag="IXT46_002516"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAQ4948406.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRAVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11552..12958
                     /gene="atpD"
                     /locus_tag="IXT46_002517"
     CDS             11552..12958
                     /gene="atpD"
                     /locus_tag="IXT46_002517"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAQ4948407.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12972..13394
                     /locus_tag="IXT46_002518"
     CDS             12972..13394
                     /locus_tag="IXT46_002518"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAQ4948408.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4539 a         2448 c         2987 g         3746 t
ORIGIN      
        1 tttcggaaaa aagacgagta tctacttttg tcataatttt actgttagca ggtttctgcc
       61 aaaattcata acgatcaacc aatgtttgtc cacgacttat tccctgagtt tccacagcgg
      121 tgaagctttt gaaaccttca cagatggccc cctcgatgaa ataagcaaca gctaacggat
      181 cattgatgac acatcctaaa attctttctt gtttccagtg gaagtcaaaa taaaaacgag
      241 tgatcgcttt taaatactct ccctcttcag gattcatttg acagcagtat tcgaggatag
      301 tcggtgtcaa gacgatttct cttgtcacat ctaacccaac catttctatc gtttgtttga
      361 gattctcgaa tacataagaa gctgcttcag gatcacacca gtaattgtat tcagcaactg
      421 gcgaacagtt accatggctt ttgtaagttc cacccatcga gacaaaacga tccatatgtt
      481 tcccaatatt tgggttgact ttcaaagcaa aagcgatatt ggtcaaagga cccaaagcaa
      541 tgactgatgt atttgtcttt tctttgaaat aatcagccaa aaaatcaacg gcatggagag
      601 gttctgcctg ttttctcaag atcatcggga aatttgtttc ccctaaacca tccataccat
      661 gagtgtcttg tgcactgatg aaaggttgct tcaaaggttt ttccattcct tgataaacag
      721 gaatgtctaa acgatcacag cgttccaggc atttcagcac attctgcgta cctatatctg
      781 cagggacatt cccacaaact acggtaatag caactacttc gatatcaggg gatttgacag
      841 ctaatgataa agctaaagtg tcgtcgatcc ctggatcgca atcaataatt acttttcgca
      901 ttatttccaa tctcctttct ttagagatac ttagtttttt attctgggaa gtttccgaac
      961 cagtccaaga cgagcgtctt gattataatg cacgaaatta gtatactggc ttttattgcg
     1021 aatgtaaatg ctctcttaca agtaaatcta ttgaggagaa ctttaagtaa atgatacaat
     1081 gaaaaagaaa tggaatttac gtgtgccgaa aataaagaat cctatggatc ggtacattgg
     1141 ataatagata gattatagtt tggcagaaag cggcgggtgt acaatggtta ttttttattt
     1201 cattcttatt ctgataatta tagggatcag ttaccatttt ctttcttatt tttatgcaaa
     1261 gaaattagta agagcgggag tacagagagg atatgactgg tatgaagaca ctggtcatcg
     1321 tttgatggac cctgctgcag tcacgtcagt agaaaaaaaa cgacaaaaat tagaagaaga
     1381 gtgtgaaagc ttttgggagc agggaacacc caaaacaatc aaaagttatg acgggttgaa
     1441 actagctggt cagatgttca tccatccaaa taagcagaat aaatgggtca tttgcgtaca
     1501 tgattaccga agcacaggga aaagagacat gtctcatata ggtaaaagat atgcagagaa
     1561 aggattcaac gttcttgtac ctgatttacg tgcgcacgga gaaagtgaag gagaaatcat
     1621 cggaatggga tggctagatc ggctagattt aattgcctgg atccaactca tcttagatga
     1681 acagccgaat gcgtccatta ttttacacgg cggatcaatg ggagcttcta cgatcatgat
     1741 ggcaagtggt gaaaaacttc catcagcggt caaaggattt attttagaca gcggatatgt
     1801 ttctgtttat gcagaattcc gatatatgtt aagtaaaatc actgtctttc ctaaaaaaat
     1861 ggtcatgaga tatgcgaatc attatgccca gaaatacgcc ggttactcct taaagcaagc
     1921 atcagctacg agacagcttg gcagcaacca tctgccttta ttagtcatcc atggtgaaag
     1981 agatcatttt gtccctacag aagcagcgta cacgattcaa aatgctacgg caggggataa
     2041 agcactgctg cttgttccag aagcagaaca cttggaagca tcgatgaaag atccgaaaac
     2101 ctattggaca gtgatttttt catttattga acaaagaata acgatggatt aattttctct
     2161 tcttttttgt aagtaattcg aggataaata attgtttata gatctggaga ctgctaaaat
     2221 aaggtaggaa taaaaaaata tcagttattt gaggagtgcg gcatatggaa atcaaagaag
     2281 aaaaaaatcg tcttgcttta ttcaatgatg agcaacaaga gattggagaa atgacatggt
     2341 cagatgcggg cccagacatc atgatcattg accatacatt tgtagatcca gcatatcgtg
     2401 gtcaaaagtt agctgaaaag ctagtgtata ctggagtaga attagcaaga cgagacggga
     2461 aaaagatcat tcctttatgc ccttatgcaa aaaaagagtt tgaaaagaaa ccagaatatc
     2521 aagacgtctt acgtcagtca taagaataac agctgaaagt tttgaacttt cagctgttat
     2581 tccatttata tagagttgtc acggactttt atctatgata aagttaaaga gacgatatct
     2641 tttgggaagg aggctgcgat atgtataatt taattttggg aatcgtgatc gttttatcga
     2701 ttgttatggt cattgcgatt atgatgcagc caagcaagca aaatagtgca gcgagtgcat
     2761 ttaccggcgg tgcggatcaa ctattcggca aacaaaaagc tcgcggcttt gaagctgtca
     2821 tgcagcgatc aactgcagtt atgggagcta tctggatgat cttattattt gtcctagcat
     2881 atttatcttc gaagtagttg aataagcctc tcgcaaaacg gcgggcggct ttttttattg
     2941 caaagagaac gcttaagaag aagttatgaa agaaactatg gtaaaatgag gcgaaagagg
     3001 tgagacgagt gagacaatta ccaaaacccc tttatgcaaa acatggaaag cgagcggttt
     3061 tgctgcttca cgcttactca ggaagtccaa acgatgttcg aatgctcgca cgatttttgg
     3121 aaaaagcaga ttatacagtt tatgcgccgc tttttaaagg acacggaaca atggagccat
     3181 atgatatctt gcaagaaaaa gcagaaagct ggtgggcaga cactaaaaaa gccatccatt
     3241 ttttacagtc tgagcagttt tctgatattg ccgtattagg attatcaatg ggcggcatct
     3301 ttgctgtacg agcactagaa gaagaatcag tgattggcgg cggttttttc tgttcgcctt
     3361 tgtctcctgt aaaaacaaac gtgcctgaaa actttgaaaa atacgtacgt caagtgctga
     3421 agacagcagg taaatcagag aaagaaatca atgaaaaagc agttgcttac cgctcgttag
     3481 ctgaacaaca attaatggat atacaagatc aggcagcaat cgtagaaagt aggttgtcag
     3541 atatccaaca gccgatattt ttagctcaag ctgggaaaga tgaaatgatc gaccctaatg
     3601 gcgtatttga aactgcacgc aagttgagcc gtcagcgagt gacacttcaa tggtatcctg
     3661 aaagtggtca tgtgattaca gttggtacag caagacgcga attagaaaaa gacgtcttgg
     3721 aatttttaga aaaattacct tggaatgagg aataaatatg acaaaagaaa cgataaaaga
     3781 gaaaattctc tttttcatgg aaagcagtcg caaacgcagt ttttctatgg aagaaatcgc
     3841 tgaaggttta gggttccaaa aaagcgatga ttttaaatta ctagtacaaa cgattgctca
     3901 aatggaaaga gaacagagta tagttttcaa taaaaaagga aaagtgaaac ttcctttaaa
     3961 accaatcttg atcgaaggaa catttcgagc aaatgaacga ggatttggat ttgtaacgat
     4021 tgatcccgaa gaagatgaca tctatatccc aaaagaagcg actggttttg caatggatgg
     4081 agacaccgta gcaatcgata tcatgaagcg agcaaataca gatatggatc gcggagcaga
     4141 ggggaaagta gtcgagattc gagaccgggc gactactcag ttagcagggg aattcgttgc
     4201 ttattcagaa gaagaaatac aagaaacaga tctttacggc gttgttatcc cgaaagatag
     4261 aaagctcaac caatttaaag tatatgcagc agcagaggga gttcgtccag ttgacggaag
     4321 tattgtgctg atcgaactga cccattaccc tgaaaaaggg tatgcgacta gtttagaagg
     4381 gataatcaag caagtgattg gtcataagaa tgaccctggc atggatatcc tctcaattgt
     4441 cgtggctaat ggtatcccta cgaaatttcc tgatgatgta ttgtctgaag cagatgaagt
     4501 tccagatcaa atcagcgaaa aggatataac tggacgtaga gatttaagaa atcagctcat
     4561 tgttacgatt gatggagaag atgcaaaaga tctagatgat gcagttacgg ttaaaaaatt
     4621 agataacggt aattattttc ttggagtaca cattgcagat gtttcttact atgtgacaca
     4681 aggcagtcaa ttggacagag aagcatatga aagagggaca agtgtatatt tgactgatcg
     4741 agtgattccg atgatcccgc aacgtttatc gaatggtatc tgttcactga atccccatgt
     4801 tccaaggctg accatgagtt gcgaaatgga gattgatcca aatggacaag tagtctctca
     4861 tgatattttc ccaagtgtga tccaaacaac agaacggatg acctacacag ctgtcaatca
     4921 aatcttagaa gatcaagacg aagaaacgat gcaacgctat gctcagctcg tacctatgtt
     4981 ccaagaaatg ggtgaattgc atcgaatcct tgaaacgatg cgaatcaaac gtggcgcgat
     5041 ttcttttgag gatcgcgaag cgaaaatcct tgttgatgct gaaggacacc caaatgacat
     5101 ccagctaaga agcagaggaa ttggtgaacg cttgatcgaa tctttcatgc ttgcggccaa
     5161 tgaaacggta gctgaacatt ataataaatt aaatctgccg tttatttacc gaatccatga
     5221 acagccaaaa gaagaaaaaa tgcagcgctt ctttgatttt gcttcagctt tgggcattct
     5281 ggtccgagga acgaaaggaa cgatcacacc aaaagattta cagcatgtga tcgaaggagt
     5341 agaagacaaa ccagaagctg cagttatcaa tactatgttg ctaagaagca tgcaacaagc
     5401 acgctattca gaagacaatt ttgggcatta tggcttagcg gcagattact acacacactt
     5461 tacatctcct attcgacgct atcccgatct aatcgtccat cgtctgatcc gttcttacag
     5521 tgaagataaa agtgaaagca atcaaagttc gtgggctgcg gaacttcctg aaattgcaga
     5581 tcatagttct aagatggaac gtcgtgcagt agaaacagaa cgtgaagtag attccatgaa
     5641 gaaagcagaa ttcatgatgg acaaagtggg agaagaattc gatgggatca tcagctctgt
     5701 tgtgaaattc ggcctgttta tcgaactgcc gaatacagta gaaggattga tccatatcaa
     5761 tgaattgaaa caggactact tccattttgt tgaaaatcat ttagctcttg taggtgaaag
     5821 aactggtctg acttttaaaa tcggacaaaa agtgcgcgta aaagtagtca aagctgatcc
     5881 agatgaacga gcagtggatt ttgaactcgt ttccgcagaa gaggtcactg cgttggaacg
     5941 tccaaaagca cgcaatggaa aatctggaaa acgagaagga aaacaagcag gcaaacgctc
     6001 agaaaaaaat ggcaagaaga acaaacgata tagtgatagt aagcaaacgt tcggtaagaa
     6061 aaaagggaaa aagccatttt acaaagatgt caaaaagaag aaaaagaaaa aataaaatga
     6121 gttggaggaa acagctatgc caaaaggcga gggaaaacta attgcacaaa acaagaaagc
     6181 tcgccatgat tattcgatca tcgacacgat ggaagcaggg atggtcttgc aaggaacgga
     6241 gatcaagtcg atacgaaaca gccggatcaa tctgaaagat ggatttattc gcgtccgcaa
     6301 cggggaagct ttcttgcata atgttcatat cagtccttat gaacaaggaa atatttttaa
     6361 tcatgatccg ttgcgcacga gaaagttatt attacacaaa aaacaaatca tccggcttga
     6421 aaatgaattg aaaaatactg gaatcactgt tgttccttta aaagtctata ttcgtaacgg
     6481 ctatgccaag gtattgattg gtctggcgaa agggaaaaaa tcttatgata aacgggaaga
     6541 tttgaaacga aaagatatcg atcgacaaat tgatcgaaca ttaaaaaatt tctctagata
     6601 atttcattat cctttttcgc atattcggtg cttttgcttt tacttaatga taaaatttgt
     6661 tagcatttaa tctgataaaa catgattatc ataggttttt tcttagatca ggagcaccgt
     6721 gtataaagaa aaattcgctt cgtttttgac tgaaataaaa aagtgtctaa ttttcatgaa
     6781 aatgttttga attttctgtt tcatggtggt atgataccgt gtggttagaa accgattgga
     6841 aaaaaccaga tacgcacatg aattgatttt atgtgaattt cggggaaaag aggtgaaatg
     6901 gattggatga acgctcgcta acgttccaca ttggaccaat ttggtttgat ggtacagttt
     6961 gtataatggt gttactgacc tgtttgattg ttttcttctt agcttacttt tttacaagaa
     7021 atcttaagtt gaaaccaaca ggcaaacaaa atgcgataga atgggtcatt gattttagtc
     7081 gaggaatcgt aacagataat ctgcctagaa aagaattgag caatttccat ttgttggcat
     7141 ttacattgtt tttatttgtt tttgttgcaa acaacatcgg tttagtaaca aaaatcgttt
     7201 tacctaacga aacaacactt tggaaaagcc cgacagcaga cccgtttgtt actttaactt
     7261 tggcatttat aatgatctta cttactcact tatttggggt gaaaaagtta ggcttcaaag
     7321 gatatttcgt aaattcgttc ttgaaaccat atagttttat gtttccgatg aaactgattg
     7381 aagaatttac aaacttatta acacttgctt tacgtcttta tgggaatatt tatgcggggg
     7441 aagttttgct aaccttgatt gcaaaaatga tgacaagctt aggctggttc tcattaccat
     7501 tagcaattcc attagagatg gtctggatcg cgttctcctt gtttattggg agcatccaag
     7561 catttgtctt tgtcactttg tcaatggttt atatgagcca taagattgaa gtagaagaat
     7621 aatactcggt taaaaaacaa actactattt atctatttta ggaggaaaac aattatgaat
     7681 tatatcgcag cagcaatcgc aatcatggga gcagcaatcg gagccggtta tggtaacggt
     7741 caagttatct ctaaaacaat cgaatcaatg gctcgccaac ctgaaatgtc tggtcaattc
     7801 cgtacaacaa tgtttatcgg ggtagctcta gttgaagctg ttcctatctt aggggtagtt
     7861 atcgccttga ttctagtttt tgccgtttaa ttgaatcagt attaaggcag aaacaacatc
     7921 gtttgttact gcttttttac atggaaacta gaaatactcc aaagaaagga aggctcgcct
     7981 atgctgaatc aattggcaat tgcagaagtt ggcaatgcga tgttaggtaa tatcatcgtt
     8041 gtcagcggct catttttgat actactggct ctcttgaagc actttgcttg gggaccaatc
     8101 agcgatattt tgaaaaaacg tgaagacaag atcgccaatg atttagattc tgcagaacaa
     8161 tctcgcatca actcagcgaa aatggaacaa gaacgcgaac aacaattgtt agcctctcgt
     8221 tctgatgcag ctgatatcat caaaaatgcg aaagaaagtg gagaattaag ccgccaaaat
     8281 attttgaagg atgctcaaga agaagcagct cgtctaaaaa gcaaagccca agctgatatc
     8341 actgtagaac gtgattcagc gctgaactct gtaaaagacg acgttgcaga actctctctt
     8401 caaatcgcgg aaaaaatctt gaacaaagaa ttatctccag aaatgcatga atcattaatc
     8461 aatcaataca ttgaaggtct aggttcttca aatgaaacta gataaatata cagtaggaag
     8521 acgttacggg aaagctttat ttgaactggc gatcgattca aatcaagcag aagaaatcta
     8581 tcaagatctc gtaagtttac gtcaaatcta tgaacaagta cctggattag ggaatatgtt
     8641 aagtgatgtt cgtctagaac ctcatgaaaa acgagaaatc atggacaagc ttgtcagcgg
     8701 ttatgatggg atcgttaaaa actttttaga agttgtttat gagtataacc gaatggatga
     8761 ccttttgttc atgatcgaag aatatgaacg tcgatatgat gaacatcaag ggttactatt
     8821 gggaagtgtc acaacagcag tcccactttc agacgaacaa cgaatacaat tagaaaagaa
     8881 tgttgcaaaa acaatggact atcaatcagt tgaattaaaa caaatcgttg attcttctat
     8941 tattggtggc gcgattgttg aagccaacca tcgagtaatc gacggaagca ttcgcacgca
     9001 attagaaaaa atgcgtaatc aattaaacag atagtacaaa gaggtaggtg aatcgaatgg
     9061 ccatcaaagc agaagaaatt agtgccttga ttaaagaaca aattgaaaat tatcaaaacg
     9121 tgctttcagt cgaagaaatc ggtaccgtaa cttatgtagg tgacgggatc gctcgtgcac
     9181 atggtttaga aaacgcgatg agtggtgagt tgcttgaatt ttcaaacggc tcatacggaa
     9241 tggcgcaaaa cttagagtca aatgatgtag gtatcattat ccttggcgat ttcgagtcca
     9301 ttcgtgaagg agataaagta aaacgaacag gtaagatcat ggaagttcca gttggagagg
     9361 ccttgatcgg tcgggtagtc aatccgctag gtcaaccaat cgacggacta ggtgaaatcg
     9421 ttactgacaa agctcgtcca gtagaagcga tggcaccagg tgttatgcaa cgtaaatctg
     9481 ttaacgaacc aatgcaaaca gggctaaaag cgatcgacgc ccttgtgcca atcggacgcg
     9541 gacaacgtga attagtcatc ggtgaccgta aaacagggaa aacttctatt gcgatcgata
     9601 cgatcatcaa ccaaaaaggt caagatatga tctgtatcta tgtagcaatc ggacaaaaag
     9661 attctacagt tcgtacacaa gttgaaacat tgaaaaaata tggcgcaatg gattacacaa
     9721 tcgttgtgaa tgccggtgcg tctcaaccag caccattgct ttatatcgca ccatatgctg
     9781 gtactgcaat gggtgaagaa ttcatgtaca acggtaaaca tgtattgatc atttttgatg
     9841 atctttcaaa acaagctgtt gcttatcgtg aactttcctt gctacttcgc cgtccaccag
     9901 gtcgtgaagc ttatcctggg gatgttttct acttgcactc acgtttatta gaacgtgcag
     9961 caaaattaag tgatgattta ggtggcggtt caatgactgc cttaccattt gttgaaacac
    10021 aagctggaga tatctctgct tatatcccaa caaacgttat ttcgatcact gatggacaaa
    10081 tcttcttaga aagcgacttg ttctacgcag gtactcgtcc agcggttgat gccggactat
    10141 ctgtatctcg tgtagggggt tctgcgcaaa tcaaagcaat gaaaaaagtt gctgggactt
    10201 tacgcctaga cttagcaagt taccgtgaat tagaagcatt tacacaattc ggttctgact
    10261 tggatgcagc aacacaagca aaactaaatc gtggacgccg tacagtagaa atcttgaaac
    10321 aaaaattgca tgcaccgcta gctgttgaaa aacaagtagt gattttgtat gctttgacac
    10381 atggattctt agatagtatc cctgtagaca gtattttaga cttcgaacat gaattattcg
    10441 aatatctgga taccaatcat tcagatatct ttgaaacaat ccgtacaaca aaagatcttc
    10501 cagaagaaga agcgttgaac agtgcgattc aggaatataa agacatgttc ttagctacaa
    10561 aaggaagtaa ttcctctaca gaagataaat tgaaatccat tcaaaatgca tagtgaggtg
    10621 agatgaatgg gtgcttcatt aaatgaaatc aagacacgta tcgcttcaac gaaaaaaacg
    10681 agccaaatca cgcgggcaat gcagatggtg tctgcttcta agttgacaaa atctgaagct
    10741 tcttcacaga agtttcaggt ttatgcaaca aaagtaagag aaatcgttac gcatttgact
    10801 gctactcagt taaatgatat tgcctcagaa aatcctagag gggatatcaa ttacaacagc
    10861 atgctgctca gccgtgctgt gaagaaaact ggttatatcg tcatcactgc agatggcggt
    10921 ttagtcggtg gatataacag ctcgatattg aaacaaacga tgtctatttt agaagaagac
    10981 caccaatcac ccgatgatta cgtgatgatc gcaattggcg gaactggtgc agacttcttt
    11041 aaagcacgcg gtatcaatct agcatatgag ctgcgcaatc tatctgatca gccaagcttt
    11101 gatgaagtcc gcaaaatcgt aaatatggca acaactatgt tccaaaacga agtattcgat
    11161 gaattatacg tatgttataa ccatcatatc aattcgctaa ctagtcagtt tcgtgtagaa
    11221 aaaatgctgc caatctcaga cttagatcca gaagaagcaa cgactttcga acaagaatat
    11281 atttttgaac cttcaaaaga agaaatcttg tctcagttat tgcctcagta tgctgaaagt
    11341 ttgatctacg gtgcgatcgt tgacgccaaa acagcagaac atgctgctgg tatgacagca
    11401 atgaaaacag caactgataa tgctgctaat atcattgatg agctgacggt ttcttataac
    11461 cgtgcaagac aaggggctat tacccaagaa attaccgaaa ttgttgccgg agcttcggca
    11521 ctagaatagt attgagattg gaggaaaaaa gatgagttca ggcaagattg ttcaagtaat
    11581 cggtcccgtt gtcgacgtgg aattttcttt agaccaatcc ttaccagata tcaacaacgc
    11641 attagttgtt tataaaaatg acgaaaataa atcaaaagtt gttcttgaag cagcgttaga
    11701 attaggggac ggagtgatcc ggaccattgc gatggaatca acagatggtt tacaaagagg
    11761 aatggaagtc attgatacag gcaaagcaat ctctgttcct gtaggtaaag aaacattagg
    11821 tcgcgtattc aacgtactag gagatacgat cgatttagaa acacctttcc cagaagatgc
    11881 ggaaagaagc gaaattcata aaaaagcacc agcctttgac gaattaagta caagtacaga
    11941 aattttggaa acagggatca aagttatcga tttgcttgcc ccatatttaa aaggtgggaa
    12001 agtcggacta ttcggtggtg ccggtgttgg taaaaccgta ctgatccaag aactgatcca
    12061 taatatcgcc caagaacatg gtggtatttc tgtatttacc ggtgtaggtg aacgtactcg
    12121 tgaaggtaat gacttgtatt atgaaatgaa agattcagga gttatcgaaa aaacagccat
    12181 ggtgttcgga caaatgaacg aaccaccagg tgcacgtatg cgtgttgctt tgactggttt
    12241 gacgattgcg gaatatttcc gtgatgtaga aggtcaagat gtactgttgt ttatcgacaa
    12301 cattttccgt ttcactcaag ctggatctga agtatcagcc ttgttaggac ggatgccttc
    12361 tgcggttggt tatcaaccaa cattggcaac agaaatgggt caattacaag aacgtatcac
    12421 atctacgaaa aaaggttcga tcacatcgat ccaagcaatc tatgtgccag ccgatgacta
    12481 cactgacccg gcgccggcaa cagcattcgc ccatttggat gcgacaacca acttggaacg
    12541 taaattaaca gaacaaggga tttatccagc ggtagatcca ttggcttctt cttcaagtgc
    12601 tttagcacct gaaatcgtgg gggaagaaca ttataaagta gcaacagaag tccaacacgt
    12661 attgcaacga tatcgtgaat tacaagatat cattgctatc ttaggtatgg atgaattatc
    12721 cgatcaagaa aaagtgttag tttctcgtgc ccgcagagtc caattcttct tgtcacaaaa
    12781 ctttaacgtg gctgaacaat ttactggtct tccaggttca tatgtccctg tagaagaaac
    12841 agtgaaagga ttccgcgaaa tcttggaagg caaatacgat gatcttcctg aagaagcttt
    12901 ccgaagtgtt ggccgaatcg aagacgtcgt agaaaaagcg aaaacactag gctactagaa
    12961 aggggtgccc catggatcaa tatttaacag taaatgtggt aactcctgcc ggtttggtct
    13021 atgatcacca tgcagctatc gtcgttgcac gtacgacagc tggtgagctt gggattttgc
    13081 ctaaacatgc accaatcatc gttccattga cgattgatga agttcgtgta aaacgaacag
    13141 attcagatac ccacgtcgat tggatcgctg ttaatggcgg aatcatggaa gttcgtgata
    13201 atgttgtttc aatcgttgct gatagtgcgg aacgtgaacg tgatatcgat gtatctcgtg
    13261 cggaacgtgc aaaacaacgc gcagaacgcc aaatcgaaga agcaaaagca aaacaagata
    13321 cgaacgaatt gaaacgggca actgttgcgt tgcaccgagc aatcaatcgt atcaaagtat
    13381 ctaagcactc ataaaatgag atgcggatgt ttatccgtgt ttaagaacag taaaaagagg
    13441 ttatgacaga agtggtcagc ttcaagacat aagaaggaat ttacgaaaat tgcttctcaa
    13501 atttttgtga aatctcagct tatttttcga agaagctact tctggaacac cgtatatcag
    13561 aggttgtaaa atcagcgttt tgtcctgagt attagagaaa caaatggaaa atagttcctc
    13621 atattttgcc gttttttgag ctaataccga gggtcagatg attgaacacc gtttatttgg
    13681 gctctttgtc aaatgatgtt ggtaaagaga aatcttagaa
//
LOCUS       DACGMI010000076        13520 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.078, whole genome shotgun sequence.
ACCESSION   DACGMI010000076 DACGMI010000000
VERSION     DACGMI010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.078"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..142)
                     /locus_tag="IXT46_002519"
     CDS             complement(<1..142)
                     /locus_tag="IXT46_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4948409.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQ"
     gene            complement(211..417)
                     /locus_tag="IXT46_002520"
     CDS             complement(211..417)
                     /locus_tag="IXT46_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948410.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYYTG"
     gene            complement(580..2214)
                     /locus_tag="IXT46_002521"
     CDS             complement(580..2214)
                     /locus_tag="IXT46_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4948411.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            complement(2218..3591)
                     /locus_tag="IXT46_002522"
     CDS             complement(2218..3591)
                     /locus_tag="IXT46_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4948412.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            complement(3607..3846)
                     /locus_tag="IXT46_002523"
     CDS             complement(3607..3846)
                     /locus_tag="IXT46_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948413.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            complement(4028..6703)
                     /locus_tag="IXT46_002524"
     CDS             complement(4028..6703)
                     /locus_tag="IXT46_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HAQ4948414.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            complement(6886..7809)
                     /locus_tag="IXT46_002525"
     CDS             complement(6886..7809)
                     /locus_tag="IXT46_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948415.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGTLGWTETYYEKIYKEIIEQYFPK"
     gene            complement(8332..9336)
                     /locus_tag="IXT46_002526"
     CDS             complement(8332..9336)
                     /locus_tag="IXT46_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAQ4948416.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKETVETDTTIEAKKSKTQS
                     TEQTTTEMKQSVEASTSESSIIESSSEEVKNTLWDSEKSTQLAIFVPQWGKTLGQEYK
                     SYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVET
                     GEYLGQHVYFFGFQNGQPKVYLTQQNQGNDKNYMYFNETQNQQLKQGFIDIVNGQTPQ
                     TPVVEESTQQATTTTTQSTSSSAISSWEAAKETVLNNKALWLYDSPDKNASNTNLIST
                     NEYMKDLMQDENGSYYSINIVTDDNGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK
                     "
     gene            complement(9407..9703)
                     /locus_tag="IXT46_002527"
     CDS             complement(9407..9703)
                     /locus_tag="IXT46_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948417.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHAGYRHSWERIN"
     gene            complement(9696..9989)
                     /locus_tag="IXT46_002528"
     CDS             complement(9696..9989)
                     /locus_tag="IXT46_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948418.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(10135..10686)
                     /locus_tag="IXT46_002529"
     CDS             complement(10135..10686)
                     /locus_tag="IXT46_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HAQ4948419.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFPRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(10860..11159)
                     /locus_tag="IXT46_002530"
     CDS             complement(10860..11159)
                     /locus_tag="IXT46_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HAQ4948420.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGMLPEDVT
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTNE"
     gene            complement(11186..11494)
                     /locus_tag="IXT46_002531"
     CDS             complement(11186..11494)
                     /locus_tag="IXT46_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAQ4948421.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQFHLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEARKEYLISPKLRLKSVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            complement(11611..12570)
                     /locus_tag="IXT46_002532"
     CDS             complement(11611..12570)
                     /locus_tag="IXT46_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4948422.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLEVDTIVGVKHKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHLFK
                     SMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            12714..13490
                     /locus_tag="IXT46_002533"
     CDS             12714..13490
                     /locus_tag="IXT46_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4948423.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
BASE COUNT         3997 a         2590 c         2056 g         4877 t
ORIGIN      
        1 attgctttac ccatttgtca aatgctgaag ctgttagttc atattctcga atgatttcta
       61 cacgtggctt tccagctaag taaagattga cgatttgttg cttgaattct tgtgaaaaag
      121 ttcttcgtgt tctcttagac ataaaaattc ctcctggtat gttttcttct agtctacaca
      181 ccttaatttt tctgtctagt taattgtagc ctatccagta taataaacat ttccttgagg
      241 tttcctttta atccccttcg gaaaatcacc ttttgtaaaa tcgctcttaa ggaaatcatc
      301 taaattacca gttctggtct ttttacctcc agtattccct gattttttag gtggtacatg
      361 ttctttagta agttcagtgt atttttcaca taaaatacac ttacccatct ttttcatatc
      421 tatccccact ctttttaatt cttatataca attatatttc aaatattcat taataaatat
      481 ccctatttat gataaggacc tccctaacta cttctctaac gatttcaaat cgctagagaa
      541 gcgttagcgc ccctctaacg ttgtttgata taacctagac tagatcgtta acgtaaaggg
      601 tgtttttaac acaaaaatag ccgtatcctt tgttttggat acggctattt gatattgctc
      661 attcaattgt tgtaccacgg catgcgtgaa tttcatcgta atttccaaca tctccttatg
      721 gttaggatca aaggttattt tctctataaa ggtacgatac aaggctttga tttgcttctt
      781 ctcactctgg gcaagaaaac gatccaaact agtcaatatc cgttggacat ctttgacttg
      841 aatcggctct ccttgttgaa agatccctaa gatttcattt tctcgaatgt gcaactgtcg
      901 tcgtttttca gtcaattcgt ctaagcggtc ttttaacatc ggaaacaatt caggactatc
      961 ttccaaagca gcttcccatt tttcaatttt agtcttcaat tcttcctttc gttccagtaa
     1021 caccacgagt tcttgttcca atggttggct ttgtcgcact atttcttcat ttaacgctgc
     1081 caccaatcgg ggaagaactt ctggtagctg aacgatctcc tttaatcggt cggcgacaaa
     1141 tgtttccgct tgttcggcac gaatcgaatt ggcatgacac acacttgctc ctttattccg
     1201 aaagactgaa caagaataat atcgaatccg tttctttgtg ccatccttta gggtatttgt
     1261 gacattactc gctgccatcg gtgcgccaca ttctggacaa cgtaacaagc ctgtcaatac
     1321 attttcacct gtatggttcc atttgggttg ttttccttct aaagcaaggc gttcttgtac
     1381 tttttgataa tcttcttccg aaataatcgg ttcatgggtt cctttcacta aaatcggtct
     1441 cggattcttc cccttccgtc gtttggtttc ccaattgatg tagcgcgcat attctaaata
     1501 ccctgcataa attttattgc gtaagatatc tttgactgcc gtggtagaaa aagcattctt
     1561 tttgactgtt tgatatcctt gacgattcaa aaaattggca atcgctcgat accctgctcc
     1621 gcctaaatat tttgcataga tcagacgaac aattttcgcc tcttctggtt caatgaccaa
     1681 ttgtttttga ccattcgtgt caataccact gacatagcct aaacgtcggc ctcctgcata
     1741 acgcttttta tctttcacta agctttgcat tgacatttga acattctccg caatttggtt
     1801 gcgttcaaat tcaccgaaac tcccaaggag ttgtaacatc aatttacctg tcgaagtggt
     1861 cacgtcaaat tgttccgaga tcgaatgtaa tcctacgtca tatcgcaata attcctcgac
     1921 tgtttgtaag acatctaaca tattgcgtcc gagacgggtc aatttccaaa tcactagtag
     1981 atcaaaacga tggttccgag catcgttcat cattcgttga taggcgaacc gattttttgt
     2041 ggatttccca ctgattcctt catcggcata aacttctacc acttcatagc ccatccgttc
     2101 ggcaaactgt cgtccatttt gttcttgtgc ttgaatacta tgtccttcta aagcttgttc
     2161 ttgtgtactc acgcgaatat acaatgcgac tcgtttggtt tgtatcattt ccatagatca
     2221 ttcgttcctt tctaaaatat tttgtgtcag ttgtcggaag taaatcccac aaactgtttt
     2281 atcctttgtt acctcaatcc gacaaacata gtcacataat aattgtcgac tagagaggtc
     2341 ttttagttga agccattctt tcacttttgc ttcacactgt tggagtgaaa gaaacgaaga
     2401 agtagacatc ggcttttgaa gagcttgcag ttgttgcttg agttcttcca gtgaacaatt
     2461 gccctcttca aatgccttaa tccattgtgc ttcttgtttc ttttgttgga ttactttgcg
     2521 tttttcatct tttcgctttt cggctaattg ttgcgttaat tgggcaatca aggcttgata
     2581 gacgccttcg tattgaaaaa aagcctgtat cttttccaat acttctgact caaccctttc
     2641 tgcccgaaga aaaattcctt ggcagcttcg gtcggtacaa tgataataat gaagcgtctt
     2701 cgtcttcttt gtattccatt gatacttcga actcagatga cgaccacaga agggacaccg
     2761 aattttttga cgtaataagt acagatacgt atctttttta gctgtacacc ttgattggcg
     2821 aatctcttgg gcttgtaaaa aggttgcttt cgagagaatc ggttcaaagg ttcctagata
     2881 cttccccaaa gatcctcctt tgatttcgcc atagtacaat ggatttttta ggatactata
     2941 aatatgatag ggctgaaaag gacgttcgcg gaagaaaagc ttttgttgcg tcaatcgttg
     3001 acaaagcttt ttgtagccat attttttggt caaataaagt tgaaaaatat agcgaacaat
     3061 ccttgcttcg tgtacttctt gttggatttt cccattcact aaacgatacc catatggtac
     3121 cgcagaagac aaatattgcc gttgttgctt tttataggaa agtccggcac gaacattctc
     3181 aataatgacg tttcgttgtt gttctgcaaa agtgaacaat aattgcacaa atagtttatt
     3241 cgttgacgcg tgtgagaaag aagcaggaag aggttcagaa atcgaataca cttgaacctg
     3301 atgttgttgg cacaactcaa taaattctaa ggctattttg gcttgacgtg ccaatcgatc
     3361 ataacgccaa acatagatca ccccctcttc ttctgacgca caaacccaag ctctaagctg
     3421 tcgaaaagct ggacgctccg ctttttcccc tgattctcct ttgtctgaaa atcgttgggg
     3481 aatttgttca tatttctcta aaacatactc tttcactgca tcatattgag cgtcattact
     3541 aattttcgct tcttcataaa cagacgttcg atcataacaa gccacacgca tgcttgatta
     3601 ccctctctat gaatgaacta aataccattt tttcacgact cttctattga acgaacgttg
     3661 cacaaagtga ttttctaaat atccttcgtt cttcaacgct tgaagagtac ccccgataga
     3721 tccagcagat acccctctta tttcgaaatc caagtaaatt ggttttgtaa aaaaggcttg
     3781 atttgaaaaa tgttcttgaa tatacagaag aacctctgct tttagtgtca ttttattttt
     3841 agtcattaga attttccttt ctttcatgtt tgattgaatg aagtaaatga agcatagatc
     3901 aagcttcatt tacttccgtt tgggtttgct cgctatcata cagataagta atcagttgtt
     3961 ttgctaaatc aataagaaat atttccataa catggtgcct cactttcata ctttggttta
     4021 ttctaaatta caatcgaaaa tacgatttga gtgaagaagg taatagaatc tcgtatgttg
     4081 gaagaacttg acgattcatg tgaatacgtt tcgttcttct ccctttttct gcacacatat
     4141 tacccgaatc aagcaattgc ctaaaaagat aggttagatc ctttacttga aattctcgcc
     4201 ttaacaagtc ctcaaacggg ataggaaaaa tatttacctt aatatcccca tttttttgaa
     4261 ttgatacttt tccccaaatc gtactgggcg tatgtttgtt gtcactgttt gttaaaaatt
     4321 tatggctatt catcaccaac aatgttttca ctcggtcaaa taccgtttgc tcacttccta
     4381 aactagtatc tacaattaac tgttcgtacg aattaataag caccgtctgt atatgctcta
     4441 atcgtaaagg atagcccagt atatcttgaa ttaggagggc tccactataa atcaaagcta
     4501 gattattacc aatgcgttgc ttcaaagaat gttcaggtaa aacagcccat agtttttttt
     4561 gagcttcgac aaaagttgct tcaatttttg taatcccttg ttcaaagagt ttcaaaagaa
     4621 ataactttat accccaacca aaagtattag aagaaagact tttaactttc tctgcgtgat
     4681 tcgcatcctt tgtaaacttg atatcagaaa attcgatata tcgaactttc aaaccagtta
     4741 atttctcatt gaaataattt tccaaacgct cttcagaaga ggtaagggtc aaaacagaaa
     4801 aagtctcttg tggcataagc tgacaattag aatctaatct tagcctttct tctcctgaag
     4861 ctaattgata gatcaacgag ctaaagttat tttgagttgc tgctcctaac tcatctagta
     4921 ttagtggaac acctccctga ttgtttgatg ctagctttat aatggcttta ttggtagcat
     4981 tcatatttct aagaaccgta gttggatttc caaataaaga ggcaataaag tgtaacgtag
     5041 tggttttacc cgttgtgctc ttgccctgta ggttaattag taaactcaaa aaagtattag
     5101 ccttcgtaac gtttaaatag cctaacacaa tagaagcaat accaatcgac caagcaagtt
     5161 ctaagttcgt tcctaaaaca tacttatgaa ccaatgcgtc aaattccgct tctgtaccat
     5221 tagttgttaa ttggtagcat gagtttttag ttaatacaga aggaatttca cgtccaaaag
     5281 aatcttgtaa ctgaaaaatc attgcttcat tttctttttt ccagccaaga gattcatgtt
     5341 caaaaaagat tggagcattc tcccgttgaa tctgtaaaaa gtcaacgact tcagcttctc
     5401 ttctagcttt aatgattaag ccatgttttg ctaattgttt aaaattatta gtttgtaaac
     5461 atccaccttc tatttctatt tcatcccaac aatgatcgac ataataggca agaacaagtg
     5521 taatgacttt ttgttcgata tttttgcgta tttgcttaat aaacatcgga caagcaactt
     5581 tttcttcttg accttctttc accaaaaata ctccttcttg attcagttta aactggtcaa
     5641 aataatattc ttgattggat tctaatgatt ctacagaagg atttacaggt tttggcaacg
     5701 gatatttttt tacaaagtct tgaatatctt tatttttatc cgaagcatgc agacaatgaa
     5761 atcgaatctt attatcagcc gtaacagaca aacaagaacc attagaatta ttcgtgtgtt
     5821 ttcttaatgg acattcgtca aatataagta aggtaactcc tttatgatcg ccctctttta
     5881 tggtataagt taattcagga tagtgagcta accattgttt atagtctgct tgaataaaag
     5941 gtaacacttc tctaaaagat ggatggcttt ttactctaga ggttgacatc atggaatttt
     6001 cttcaactat ctgttcaaga attttaaaac aattacttct atctatgtta tcgggaatag
     6061 aaaggaaact agataaacga tgcggacgct cttttgtgga ctttcctttg accgctggtg
     6121 taccaactaa tttgcataat cttgaaggat tataaacaga agtatcaata tcaacttcat
     6181 cttctactcc aaatcttcgg tgaagtaatt gaagaaaatt ctgaatagta agaatcgtct
     6241 cgtgattatt tggttgttca tttatgggaa gaaaaatatg gtagccattc ccactatcaa
     6301 cttttacaaa tgattctatt ctcttttctt tcaaataacg ttctacttgt tccataacat
     6361 tttctgcctt tttcttttcg ctatctgttg cacttccctc tttcctttta gggtcaatat
     6421 caataaatac aaaccgaatt ttttcaatat cattgtctct cacagaatgc tttttttgtg
     6481 taatcacctc ttgtttaata ggattataag ttatgtttac tgtaccttca gacaatttct
     6541 gtttttctaa atagttaata attgcttgag aatctgcagt agaaaaaata tgagaaacgg
     6601 ttttcttgtt taatgtagaa aaagttctca aattaacata agaaatcccc agtgtattta
     6661 acagttgtaa atgcttctga attgaagtgt gattcatttt cattaattac cactcacttt
     6721 ctaaaaaatt tttatttgta tgactacatt acctccaacc tctcataatt tcatgatctt
     6781 cagttctaca aaaatatatc ccactcaaaa tcttgacaaa agaaaaaagt tgtgattttg
     6841 gaaatcacaa cttttttctt ttacgataaa tcaatcctta ttaaattatt taggaaaata
     6901 ttgttcaatt atttctttat atattttctc atagtatgtt tctgtccatc ctaatgttcc
     6961 tataaaatca agtcctctac attttaaagg ttcacttaaa ctattaatat agttaataat
     7021 gttgtctatc cttttctctt tatcttcacc ttcaatctgg ggagcatata gtccaatttc
     7081 ctcccaataa tatgaatctc tttcaattcc catgatggta gctttggcta atttcaaatc
     7141 aaataacgat tttagaattc ttagtgtctc aataaagtct tctctcttca actctttaat
     7201 ccattgtgaa ttttctggat tatctaaaat ttcaagttca tcttcattat aagtatattt
     7261 caaatttgac ttgcttaact catagataaa tgaagtttct tgactcataa ttcttttaag
     7321 tacttgacta taagtttcgt ttgactttgc ccatttcgct aattctacca ctgtattcac
     7381 taataaatcg aaataatgat gttctcgttc aatagtctca gcattttgaa aatgaaaatc
     7441 acctttataa actccattct tttccactgt tttattaata ttttttaaaa accagaatga
     7501 gtttgcaaat ttagtcgtac tttttcgatt aactaagtta ataactcttc catgtaataa
     7561 taagacaaaa atacataaat ttttagcttc cttattatta gatactaatt gatcaatcat
     7621 agggagccat tttttgattt tcactaattg attgctcata aatctttcac tggacttttg
     7681 ttcaatctta aattgcaaaa cttctaactc ataattccca tcttctgatt tatttttggg
     7741 aacaactatc aaacttttat aaagtttatc cacatcaaaa tttatctttt ttgcataatt
     7801 tgtagccatt aatacatctc cttattcata ataaatttca tatgacgctc ctctcaaaat
     7861 ttaccggtag actagaaaaa agaataaaag atacgtcaat tcacacttta ttcttaaaaa
     7921 aaaactggtc tctctaccgg taatatcgat tgagtccgcc tttatcgact ttatcctttt
     7981 tttatattaa attttttcac cggtagacag ggagagaaag aataaactaa aaagccctta
     8041 attcttaatg ttttcacctc cttaccgttc ctaccgctaa aatttaatat aactaaattc
     8101 tataacatta gaagaaattt taaatacctt tgataaaaaa tattgatgtt ttttctctca
     8161 ttgtttacaa actagatagc ttatgtattc ttattaaaaa taatagatat ttcgaacatc
     8221 atcactctca tctacttaat ttcgcatttt tactttataa aaaaactgat tctaagaaaa
     8281 ttaaataatt tttctcaaaa tcagtttttc tttgataaat aatattttca attatttaat
     8341 catttgaaaa ttgttagtca ttccaatacg ttgagaaatt cttccatctg tataaacacg
     8401 gaattgtttt ccaccagcca ttgttgtatt tccattatca tccgttacaa tattaattga
     8461 atagtagctt ccattttcat cttgcattag atctttcata tattcatttg tgctaattaa
     8521 attagtattt gatgcatttt tatcaggaga atcatacaac cataaagctt tattatttag
     8581 tacagtttct ttagcagctt cccaacttga aattgctgag ctacttgtag attgtgtcgt
     8641 tgtagttgtt gcttgttgag tagattcttc tactactgga gtttgaggag tttgtccatt
     8701 cacaatatca atgaaacctt gttttaactg ttggttctga gtttcattga agtacatgta
     8761 gtttttatca ttgccttgat tttgttgcgt taaataaact ttaggttgtc cattttgaaa
     8821 gccaaagaaa tatacatgct gccctaaata ttctccagtt tctacatcag aataaactgc
     8881 tactaaattg aaatctgcat gaccagttcc atcttctgac cattgtacgg taactggtgc
     8941 ttcattgatt gccattttcc aatttccatc aataactgca cttggtaaag gcgtaccata
     9001 cagacttaca ttgttctgag gattgtagct tttatattct tgacctaatg tctttcccca
     9061 ttgtgggaca aaaattgcta gttgagtaga tttctcacta tcccacaaag tatttttaac
     9121 ctcttcagaa gaagattcaa tgattgaact ttcacttgta cttgcttcca cagattgttt
     9181 catttctgtt gtagtttgtt cagttgattg cgttttactt tttttagcct caattgttgt
     9241 atcagtttct acagtctctt tagtcctcgt attctcagat gtacaaccag tgaataaaat
     9301 ccccattcca attagtaata acaaccattt tttcatttta tttccccctt tcaatttctc
     9361 cctcgcgtac ttattttatc agtcaattaa tctcaatggt gttcatttag ttaatccttt
     9421 cccaagaatg tcgatagcca gcatgacaac gatctcttcc ttgagggctt tcagatggat
     9481 taaaactagt agaaatttcc cttccacatc ctctacagcg ataagttctc attatttttg
     9541 ggctattagt attatttttc ttagttagag ctatgagtcc aactatgatt accccaactg
     9601 tcttaattac ttttccttta tctatattcg gatgcgcaag catatattta tataaccaat
     9661 atccaccgta aattaaacca cctaatacaa tcagcttagc catgtactcg tctcctttct
     9721 ttttgtttaa ttactttttg aatccatctt gcagagaaac cataaacttc tgtcaattga
     9781 cggatatcta cagttttttc ctgttctatc atgttttcga ttctttttct aactaactca
     9841 cgatcgtaca ttttcattgg aaaagaaatc tgttgccctc gaaaagcaag ataaaattga
     9901 tagagcaatt ctgaatccag ttccatttcc tcaaaaaagt cattcatact tttataagag
     9961 ttactcaaac aagtttcatc aatctccatc tacacacccc ctgttatttt ttacataatg
    10021 aaaatagcat attactgggt acattgataa ttcatataac atgtatcatc acatgtattt
    10081 ttaaagtcaa aaagcatgta aaactactta taagtaacat aagaaaataa aatgttattt
    10141 ttcttgaaat aataattgac tatctgccaa ttgccattca ttacgaacat gaatacttag
    10201 tgggtgggat aacttacctt ctgcatttat caatactttg gtcatctttt tttgtttcgc
    10261 actcaattga tcgtaaatgg tcttcgcttg ttcataagcc acttgactcg tcgctgtaat
    10321 cgaaccacaa gcaaaaataa tggtgttgat tttcttttct gtgaaaacag ttgttaatat
    10381 ttccaaagat tgttcatcat ttccacgagg aaatacccga ggacttttcg cttttgtata
    10441 cgaaaaaaga ttcacagcaa taaaaccagt aaatcctaat tgtcggatat tcttttcgat
    10501 taataacata ctcaaatcat tcgtaaatgg ttctgtatct gttggacgaa tagtaatgac
    10561 taccgctaat ttatcttccg cttcttttcc tttgatcgcc cattgtcgtt tgaaaacata
    10621 gcgatgggta tgatgaggat ctcgccaaac ttctgtttgt gtggtcacta attctttttc
    10681 aatcatctct ttttctccta tgctaatttt tgttcaagca attcaatcac cattgccgtt
    10741 ataagtgtca atactagttg aaaatatttc atattctttc tccttttttc ttcagaattt
    10801 gatgaatcgc tgtaaggata tcttctaaac atttcgcaat cattctcaaa taatcgatct
    10861 tattcattcg ttcctccaat ctgactccaa accaatcgtc cttctaccag taacccacga
    10921 acaaattctc gctggctggt aatatctgta atgaaataaa ctacatagtc ttttccatct
    10981 tctggtgcgc aataaatata aagatgtgtc atcactaaac gtggtagagt aacatcttca
    11041 ggaagcatac ccatttcaat ttcctctttt tccatcgtaa cggattcata gccccactct
    11101 tcaggagtag tgactagctg tgcacacttt tccagtactt cgatagccgt ttctaacaag
    11161 tcctttcgtt cctttctttt agatatcagt attcttctgg taataacatc gtttgatact
    11221 cacccgaatc aatgacccat attttttgag acactgattt caaacgaagc ttaggtgaaa
    11281 tcagatactc ttttcttgct tctggttctt cttgacgatg aaccaacttt tgatttcctt
    11341 tttccgtaga aaattcaaag atttgaagat agtctaaatg aaattgcttt tgaacgtttt
    11401 gatcgattag attccaacat aaagcttgta attccaccgg caaactgtcc attactccct
    11461 ttgtgacata acgttgtcct ttattttgaa acatttcttt tccctccttt gccataaaaa
    11521 tagcccaatc ttctattaaa gaagattggg cttcatggat ataatatata tttgatattc
    11581 aatttgattc attttatact atctgatttg tcaaattaag ctagacaata tgtctttatc
    11641 tatgcagctc aaaaatactt ccaatggtgt tcgataattt aatgattttc ttggaatatg
    11701 gtttcttttc gaggcaacgg attgaataaa ggtttcatcc gtgtccctaa agtccattgt
    11761 tttaggtaag ccatctcgtc taagcaagcc gtttgagtgc tcatttagcc ctctttgcga
    11821 aggtgttcct ggatctgcga aaaagatggc aatatcgttc gagttactta tagatcgcca
    11881 gttggaaaat tcttttccac aatcaaatgt catggattta aacaagtgtt taggcatgga
    11941 tttgaaccaa tcatttaacc tgttttcgat atcttcggct cgtctgcctg tcggtttcaa
    12001 agtaataata accttggata aacactcaac caatgtaata acagcgctct tgtgtttaac
    12061 tcccacaatg gtgtcgactt cgagatgacc aaattcttta gtcaggtgtg gatagagact
    12121 gttccgttca tgaatcgttc tgcgaaaggc ctgttttcca cgcttttctt gatgattatt
    12181 cggtttacgt ttccccttca taggtaacga ctgtgtgtca aaaaggcctt ttttaaacat
    12241 ccgatagagt gtacgaacag aacaatcaat tggaaactcg ccacggccga taatcacatc
    12301 gggtgaccat ccttgagcta ccttttcttg aacatatgtt gattgttcat cagataaaac
    12361 ggttgaacgt cgtccacaac gagatttatt ttgtttgtat tgacggtaat aatctagcac
    12421 tttttttcct tgtttgagaa acgaataaac attataaatg gtttgtctag agcgatttaa
    12481 actttgtgcg acaagagcga caggtttctc gatattgaaa taagactcta tgattactag
    12541 ttcgtctgtt gtaagatggg tgtaagtcat ttgtactcac tccttattaa ttctttggtc
    12601 ggaactattt tgagtgtagc acaaatgatc tttttagttg tctagcttaa ttttacaatc
    12661 gacgttttaa taaattgtga tataatgaag tataactttt tagggagtgt actatgaatt
    12721 ttcaagataa tagaccatta tatttacaag tagaagcttc tatacgtaac gatattcgtg
    12781 aaaaaaaata tcttccagga gagcaattac ctacagaaga agaattatgt aaaatttatg
    12841 gagtaagtaa gattaccatt cgaaaagctt ttaaactttt agcagaaagt ggaacagttg
    12901 aacgattaag ggggaaaggg acctttgtaa ctcaaaaaaa agaaagttta aaattagctg
    12961 gagttcatgg atttagcgat tctctttcta cccgaggaca taaaattaga tatactgttt
    13021 tacattctaa aattataaag gctgatgagt ttttagctaa taaattacaa atcaatgtaa
    13081 ctgatagagt ttacaatatt aaacgtttaa tgtgggaaga cggtgccccg atgggaattg
    13141 ataatttttt cgcatcagaa gaaaaatttc caactttatt tgaaaaaggt agccaatata
    13201 cttcattata taaacttcta gaagatgact atgatgtcaa agctacgagc tctattatgg
    13261 aaataaacgg tttatctgca acacctgagc tttccgactt attgcaatgt atagtaggag
    13321 atccgctatt tattttagaa aaggttggca aagataaaaa taatcaacca tttcattatt
    13381 ctcaatccac agttcgttgt gatagaatta gttatgttat tgaagtcaca gaaaatatca
    13441 ctttagatac ggtgcataaa aatgattcag atcctaaagt aatagattga tattaaaaga
    13501 aatcataccc aaagcaatca
//
LOCUS       DACGMI010000077        13326 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.079, whole genome shotgun sequence.
ACCESSION   DACGMI010000077 DACGMI010000000
VERSION     DACGMI010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.079"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            261..1130
                     /locus_tag="IXT46_002534"
     CDS             261..1130
                     /locus_tag="IXT46_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAQ4948424.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1339..2364
                     /locus_tag="IXT46_002535"
     CDS             1339..2364
                     /locus_tag="IXT46_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAQ4948425.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2403..3353
                     /gene="manA"
                     /locus_tag="IXT46_002536"
     CDS             2403..3353
                     /gene="manA"
                     /locus_tag="IXT46_002536"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAQ4948426.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3447..5150
                     /locus_tag="IXT46_002537"
     CDS             3447..5150
                     /locus_tag="IXT46_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4948427.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5152..7185
                     /locus_tag="IXT46_002538"
     CDS             5152..7185
                     /locus_tag="IXT46_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4948428.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7196..7636
                     /locus_tag="IXT46_002539"
     CDS             7196..7636
                     /locus_tag="IXT46_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4948429.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7836..8963)
                     /locus_tag="IXT46_002540"
     CDS             complement(7836..8963)
                     /locus_tag="IXT46_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4948430.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8966..9643)
                     /locus_tag="IXT46_002541"
     CDS             complement(8966..9643)
                     /locus_tag="IXT46_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4948431.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9907..11673
                     /locus_tag="IXT46_002542"
     CDS             9907..11673
                     /locus_tag="IXT46_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAQ4948432.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11688..12125
                     /locus_tag="IXT46_002543"
     CDS             11688..12125
                     /locus_tag="IXT46_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4948433.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12138..13289
                     /locus_tag="IXT46_002544"
     CDS             12138..13289
                     /locus_tag="IXT46_002544"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAQ4948434.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
BASE COUNT         4517 a         2319 c         2752 g         3738 t
ORIGIN      
        1 tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatag gaggagctat
       61 ttttgtttgg ctgttcttat tacttgatgc agaacagctt tttcacaacc tctttttata
      121 agagttttta ctcattaatt tacaaaaaac aagcaaaatg cgaattttct cacatttttt
      181 ttaacaaaat caaagttatt gcttgaaaga agaagaatcc atcgttaaaa taaagcttga
      241 cgtagagggg agcaagaaat atgaaagatt ttcaattggg ggctgccacc tatttaaaaa
      301 gtgtagccat tcgggtgaaa gaccgagata aaatgattga tttttacaag aacgttgttg
      361 gctttgattt gaaaagagaa gaaaacgaat tagccatttt aggaacagaa gaagctggaa
      421 gtgaaatgtt gctgctggaa gaaagtccta gagcgaatga tcacatgggg gtgatcaaaa
      481 agctgaaccg tttttcattg attatcccta gcacagaaga aatggcagat atcctttgtc
      541 gtatccgtaa aatgaattat ccaatcaaag aagctttaga agatcatgga cgtatgggga
      601 ttttgctcgt agacccagaa gagaatgaat tggaaattta ccatgaagag aataagaacg
      661 accaaagaga aattccagaa acaatggatc aagaagcatt attaagaaaa tctgaagaaa
      721 aattcagtaa actatcaaca ggttcttatt ttgaaaaaat ccatttaaat gttactaact
      781 taacaaaaga acgccaattt cttaatcatg tacttggttt gaaggtacat aatgaagaag
      841 agggcatcca tgtattgaat gaaggagatt tccatgttgg tttgacagaa gctagcggag
      901 gcgcaattga tttgcctaca gatgaagtga ttggacttga ttttctgaaa ttcatgatcg
      961 atactgaaag catggaagga ctgattgctc acttgcagca actatcagtt gatttcttct
     1021 tagacaaaaa gcacacagta ctcacaatct atgatgctat aggaatcgaa tggtggttcg
     1081 tcagtgagcc aaaagaaaag aataaaactg acattcgatg cgacgcttaa ctttttcttt
     1141 cttaacgatt gtcgcatgtc tcgtcatttt atgaacggtc atactatcgc ttattctaga
     1201 gatagaaaga gaaaatagta taccggggga aactgcgcgg tttttcgcgc agtttttttg
     1261 tgtaaaaaag gttgattcct catagattaa gctttaagct tggactgtaa gaatctgata
     1321 gaaaagcagg agaaaaagat gtatccacac acgaaacagc ttattttgaa aaagatggaa
     1381 gaaggatttt atccaggtgt agcagtcgcc ttcataaaag aaaatcaagt agaaacattt
     1441 acagccggct ttgcccaagt cgttcctgaa aagcagctga tgacagaaga tctgttgttt
     1501 gatgcagcct cactgacgaa agtcgttgca accacttcat tagttttacg tctattagaa
     1561 gatggaaaga tagaactcga tcaaccgctt cataaatatc ttcctgaatt tgaaaatcag
     1621 acaatcactt tgcgtcattt actgacacat acttctgata tcaaaacatg gataccaaac
     1681 agagataagc tatctcagga agaattgatc gccgcttatt tgaagctaga accaggtgag
     1741 caactaggaa aagaagtaaa atatacagat gccggtacga ttcttcttgg gttgatgcta
     1801 gaggaaattt accaagaaac tgcagtggaa atctttcaag aacaagtatt ggaaccatta
     1861 ggaatgatga acagcttatt tcttcctttt ccttccaaaa aaatcgttcc cacagaacaa
     1921 ctgccttcgg gtgaggtttt gcgtggacaa actcatgatc cgaaagcaag agttttggct
     1981 gaacatgcag gtaacgcggg tctctttatt gatttgaaag acagcattac ttttgtccaa
     2041 atgtatttga acaagggaaa aatccgtaat ggtcgttttt tagaagaaga gacgattgat
     2101 tctttactgc aagatcaaac accgaaaaaa aatggctatc gttctttagg atgggactta
     2161 aaaaaggatg tagaagacgg tcatgcgatt ctttttcata ctggttatac aggtacgttt
     2221 ttcttgattg atataaaaac acaagaagcg ttgatatttt tgtcaaatcg cgtacatcct
     2281 gtcgatcatc gtgcggagta tctcatatgt cgagatgaaa ttgttgaaaa ctttttgaaa
     2341 gagaaagcgg tattaccgaa ataatgctat aatagctatg aaaaatgaga ggagtttgaa
     2401 ttatgcagga acctatgttt ttaaaaccag tttttcaaga aaaaatttgg ggaggaagtc
     2461 gtttacgttc agtctttggt tttgatatcc ctaacgataa aatcggagaa gattgggcga
     2521 tcagtgcgca tcctcatggt gtcagtgtag tagaaaatgg cgaattcaaa gggaaaagat
     2581 tagatgaact atggtcagaa cacaaggaat tgtttggcca tccttcagaa ccagtgtttc
     2641 cattattgat caagatctta gacgcagaag atgatctatc tgtacaagta catccagatg
     2701 atgcctatgg gatgaaacat gaaggtgaat taggaaaaac tgaatgctgg tatatcatcg
     2761 atgctgaacc tggtgcagaa atcatctatg gtcatcatgc aaagacaaga gaagaactag
     2821 ctgagatgat caaagatggg cgctgggatg accttttgaa gaaagtacca gttaaaaaag
     2881 gtgatttctt ttatgtacca agcggaacga tccatgctat tggtaaagga atcatgattt
     2941 tagaaacaca gcaaagttct gacacgactt accgcgtgta tgactacgac agaaaagatg
     3001 cgcaaggaca aacaagagag ctgcatatcc aacaatcgat cgatgtaaca actgtccctg
     3061 cgaaaacacc agaattacaa atcaaagaag tccgaaaagg gaattcatcg atcgtcactt
     3121 atttagaaac tgagtttttc aatgtatatg agtgggatat taaaggaatc acatctttca
     3181 aaaaacaagc cccttataca ttgatgacgg taatcgaagg agcaggagac cttgtcgttg
     3241 acggaaaaac atatccatta gaaaaaggaa caagctgtat tattccaaat ggcgtttctg
     3301 agtgggcggt ccaaggtgaa ctagcaatca ttgcgtctga accaggcaaa tagttcccag
     3361 atagctgaaa gcagcagacg gtttttcgtt tgctgctttt tctacataaa atccgtccat
     3421 caataaatag aagtctggtg aaaaagatgg aatacaaatg gaaagcaaac aacagcagtc
     3481 gcgtgtctat gaaacaactg agaaaagctg gacatcactt aaatgaaatg atcatgccaa
     3541 atctaagtct gtttatcgct tggggaatct tgtcattagc aacaaaaggt gtgtctggcg
     3601 atttgcacac cacattagaa gaggtatgcc attggatgat ccagctgctt ttacccatct
     3661 tgatcagtta ttcaggcggg aaatcggtag ggggacaaaa aggggcagtc gccggtgcaa
     3721 ttgcttcttt agggttgatc gctcgttcca atgctccaca aatcgtagga gcgatgatta
     3781 tcgggccgct tgccggcatc gtatatgaac aatttgtttc tagattccat gtgaaattca
     3841 aggctggata tgaaatgctt gtcagcaacc tactagtagg actgactggt agcgttattt
     3901 gtataattgg aatcgttttt attgaaccag ttttaaatag tgttcacttg ttgctcgcct
     3961 ccgttgtgtc ttggctagtc acaatgaatc tgttaccact tgtcagtctg atcttagaac
     4021 ctctaaaagt actatttttc aataatgcaa tcaatcatgg tgtattgaca cctttaggaa
     4081 tcgaattctc acaaacagtc gggtactctt ccttattttt gatggaggca aatcctggac
     4141 ctggtttagg gatcttactt tctatccttt gttttgcaga aaaacaggaa aaagtaaatg
     4201 cgagtggagc attgatgatc catgcgattg gcgggattca cgaaatctat tttccatttg
     4261 tcttgctgcg accgtatcta tttttagctg taatggctgg tggggcaagc ggcacgttga
     4321 tatttcaatg gttagatacg ggattagctg cacctgtatc gcctgggtca ctactcgtga
     4381 tttttgccaa tgcgccttat ccacaactag ctggggtaag tatagggata gcaatcagta
     4441 catttgtgac cttcatttgt gcagcgatac tattgaaatt accaaataaa gaaaaagaga
     4501 acaaaacggt caaagaaagg ggagaaatct tggaaccatc tatcattcat tccgtcattt
     4561 ttgcttgcga ctcaggtatg ggatcaagtg ctatgggagc cgccctgctg aaaaagaaat
     4621 tagcagcaga aaaaatcgat ctttctgtcg gatacagctc tatctatgaa ttgaataacc
     4681 aagtaaatca gctggttatc gtgcaacatg aactagcggg tcttgcaaga gaaaaagtac
     4741 ctcaaagtca aatctatgta ctggatcact ttttggaaac agatatcttg ctgtcacgaa
     4801 taaaagaagc gatccaattt ccaaagcggg aagaaaaaaa agagatagca gatatcacag
     4861 aacaaaaaac gtcgcctgct aatattgtat ttttgtataa aaacaacaga cgcggctcac
     4921 aaactatggg catgacgatt ttaagtcaat tagcaaaaaa agcgaaaaaa cagtttgtta
     4981 tctcaaaaga atcaatagaa aaaatcaaaa tccaagaaga aacgatttat atcgcacaaa
     5041 gagaactagc tgtaactgaa cagctagaag aaaagatccc tcggctagtt ctagttgaac
     5101 attgggtagc tacgaatgaa tacgaaaaac tcgtgaaggg agaaatataa gatgtattta
     5161 tcgcccagag aaaaacaatt attagcagaa tttctcagta gcccgtcacc tgtatctatc
     5221 caaaaaatga tgaatttatt gaaggtcagt aaacggacta tttaccgcga attagataat
     5281 cttgaagtct cattgaaatc ggtaaatgct tctttgaaaa aagcagctag aggctcattt
     5341 gtcattgagg catcagaaga agtattagag caattaaaag aaaatacaga tgggaaaagt
     5401 aatgacttat ccactgctaa acgacaacac gcgattttag ccgagttgtt actgacgaca
     5461 gagccgttga gtcttgctca tttcatggaa tcatatcgca tcagtaatac cactttttat
     5521 gcagatatca aacagttgga agaaagtatt cgccaactgc ctttggaaat cattcggaac
     5581 cagggatacg agatcgaagg accggaaaaa taccgccggc ttctgacagc gaatgtatta
     5641 gaattagaaa tcaatgaata tgaacttttt catagtattt ctttcgatgc atcactgaat
     5701 tatttttttc gattcgttga tccgcaacat ctatctcttg cacgcaaagt aatcggggaa
     5761 gaattgatcc aaaaaaagac caatctaagt gatagaaagc ttgaacattt ggttttgatg
     5821 ctgacattga cgatggagcg tgtgacgaaa aatcatttac tgacaaatga gacatataat
     5881 agtctggcaa acaaagaatt actacagaca gctaaacgat tgttttcacg gatcgcttct
     5941 gagacaaaac aactttatcc agtaaatgag atcgtctttt ttgcaggatt attaaatgac
     6001 ttcacgaact catttgatca gaatttcttt gaagagacgt tcgatacaca gcttgcttat
     6061 ttagtaaaac aactgattca agaagtaagt gaagagacga atgtccattt ttatgaagat
     6121 gaaactttgt acaaaatgct gttgactcat ttatctggtg tgttttcaag agccgtttta
     6181 caagaagaga cactgaccaa tccgatttta gaaaaaatca tggttcaata cgaggaagtt
     6241 gcgaatgcaa tccgtaaagc agtagagcgg atttttcaag aaaaaaaatt atccgaagaa
     6301 gagatcgctt atatggtcct tcattttgcg aattcattgg aacgaagtcc gaaagaaagc
     6361 aatatcagta ttgcaggatt ttcgccaagt ggattagctt ctactagcat gttggaacta
     6421 cgattgaaaa ggtattttcc cttcatccaa caaattcatt tctatcggat tgctgattta
     6481 aaaaaaatcg atttacaaga agaatatgat gttgttattt ctacatctat tttaccagga
     6541 tacggtggaa aatatatttt agtctccccg ctactgctag aagatgaagt caagcagcta
     6601 aaagaagctt tttcgcatat tgagaagaaa aaaaggcaaa aaattacgta taacagcaat
     6661 aacgagtgga tgatagaaga tacttatgag gaaacaatgc atttcatgga tcaaatcaat
     6721 caattactcg gtcgtttttt tatccaagaa ctggataatc ctgagacgat ttccgaaacg
     6781 attcgcagct tatttcctta ttttcctgaa ggactagtaa cggatgaaga ggtggttcat
     6841 cgccggctgc ttaagcgata tgaacaagca cctatcggta ttcctcatac aaatatgggg
     6901 ttattccata catccagctc attgatttct aaaccgatct tttgtatttt caatttgaaa
     6961 catccgttga ccattgaagg gatggataga cagccagtcg atttgtcccg tatgttagtt
     7021 atgctggcgc cttcgccaat ccaagaaaaa gacgggattc ttttaggaaa gatcagtgga
     7081 gcaatcatca tgaatgactt gaacaccgag atcttccgct caggaaataa agaaatcgtt
     7141 tatcagttgt tagcgaaaat cctgattgaa gaaataaaga aatgaaggtg aaaagatgat
     7201 acagctacca gcagaaaaaa tattgctcga tcaatcctat caaaattgga aagaagcgtt
     7261 gaccgagatc ggccagtgga tgacccaaca agggggaatc aaaccggcat atatccaatc
     7321 aatgatcgaa agacaagaaa aagcgagtgt ctatatcggg aatttcgtag ccttgccaca
     7381 tgggactgac aaagatgaag aagtagtaga agaaggaatc tatttagtcc aagtgcctga
     7441 tggtgtggac tttggaacaa aagaggaacc aaaaatcgcg acactcttat ttgtagtggc
     7501 tttaaaaaaa gaacatcagt tagcggtgct ccaagattta gcctttttct gttcagacat
     7561 cgaccaagta atggcgctca gtgatgcgga aaccattgaa gaagtccaaa tgatttttga
     7621 acatggacat atataaccaa tgttcacagt aaaaaaagct gccttgcatc aagtaataac
     7681 ttcaaccaag ataaaaataa gaggagctat ttttgttggg aggttcttat tactgcggat
     7741 gcaagctttt gaaaactatt tattctagaa aaccgtttat ttgaaatagg ggacggtgac
     7801 aaggtttttg tcaccgcccc tattattttt gtgttttaat agctcttttt tatatagata
     7861 gtgcccatac ctatgaataa taaaacgata ctccatatac caagtgtcaa gataccattc
     7921 atgaaagtaa cctgttctga agctagtggc gagaaaatat ctcctcctat gatcacattt
     7981 tgaaaatcaa cataagaagt tggcaagtaa tgactgattg attctatcca tccaatcgaa
     8041 gaaaacaagc gatactctgc taagaaaaga caaagaagtg tacctaaaag attgactaga
     8101 gaatgttcaa ataaagcaga tagaagaaaa ctgattgtac ttaaaaagag cacccacaac
     8161 aacaggaaca gaaagctctg gaaaagatac tcatacatcg gcaggattcg tatctcctga
     8221 ccaatgatcg ttcctacagg ataacggaag tctcccaaac catttttgat tattactagt
     8281 atagagacga tcaaaaatgg catcacgaga cttagcatag ctgcaccata ataaatggta
     8341 aaacggatgc tatgtttctt taccatacta tccggtaata gattgactag agagattacc
     8401 tgctttcttt tttcataaga gatgatggaa gaaagaaaca aggcggttat acataaaatc
     8461 aaaaaactag aaatcattcc tgaaaaaata ttttcgtagt aatttgctaa agagagatgc
     8521 gctggcaagt caaaaataga atatctttgg atctgatgtt ctttcatata acggagcaac
     8581 tcgacacgtt tttgttgttc aatgattgga attccttgtc tttgaccaga aatcagtcga
     8641 tccagtatat ctttttcata atgataagtt gcttcgacca tttgctggac attccctgtg
     8701 ttttttgcat gtaagattgc ttcgatcagt ttgttgcttt tctctaaact ttccacaaat
     8761 tctttctcat tctcatcttc tttcaacgtt tcaatcaaac gttgcatctc ttcatagtta
     8821 tgattcagtt catcgaattc tgtataagca agtttatgat caaaaaaaag tgggaatgca
     8881 aagagcacga ccaacaatag aggaaataaa aagtttactt tgttttttag taagagattg
     8941 cgttcaaatg taagtaaaga catagttaca cctcatataa tttacgataa atagctaaaa
     9001 tctcttccat atttgaggat tctgtgacga tttctccatt ttttagaaaa catgctttag
     9061 aacaaatcga ttggatattc gcgatagcgt gggaagaaag aagaatcgtc ttcccctctt
     9121 tctgccattg tctgatgagg ctattcaaga tatcaatact tcctgggtct aatccgttca
     9181 acggttcatc gaataacatg acagatgaat cactgatcaa gtaagcagca agcaagacat
     9241 gttgtttcat tcctagagac atttttccaa tcggcaaagt aaggtactca gtcatcttca
     9301 atcgttggaa aacagtttgg cattctactt tgctctgcca atagtatttg atcaaagtca
     9361 aataatcaac agccgataga tagtcggata actgattcgt tgattctaga aaaaagaaag
     9421 accggcgata atctgtataa gcagtaggag agatgttgtg aagggacaat tgatcataag
     9481 ttgttggcag cagttgggca atgccattca gcaaagttgt tttgccaaat ccgttcgggg
     9541 caatcaaagc agctacttct cctgattcta ctaaaagatt caattgtcga atcacacgtt
     9601 ttttaccacg tttcatgttc atgtttttga tcagtaatgt catagatagg cctccaatat
     9661 aaaatttaat aacataatag aatggaaaac atctaaatta aatgctaaca aaagttattg
     9721 tttgcatatt ataaaaaaat taaaataaca gttttattta aaattgaagt tttctgatac
     9781 cgaaatcttt ttattttgct gacatactca aacctttggc acaaagtttc gtgccaaagt
     9841 acgactattt ctctttttag taagcggata caattagagt atcaaaagga gagagggaga
     9901 gacaaaatgg aacggacgat tcccaaaaac aacatttcgc taaaagcgag ggtacaaaaa
     9961 ttaggcagta ctttatcaag catggtcatg ccaaatattg gagcactgat tgcctggggt
    10021 gtattaacgg ctctatttat cccagatggt tatttaccaa atgaggcttt cgctaccatg
    10081 gtaagcccaa tgctaactta tctgattcct ttattgatcg gttatactgg cggaaaagta
    10141 attgctggtg accgcggatc agttgttggg gcaattgcaa cgatgggtgt gattgtcgga
    10201 acagatattc caatgatgct aggcgcgatg atcatgggac ctcttggtgg atatgccatc
    10261 aagaaatttg atcagctatt ccaaaaacgg atcaaatccg gttttgaaat gctagtcaat
    10321 aatttttcag caggtcttat cggttttgga ttagcgttat taggtttttc tgcgattggt
    10381 ccagttgtcg atgcattgac tcaagcaatg gcaaaaggtg tagagatcat tttatctgcc
    10441 catttgattc cattgacaag tatttttatt gaaccagcaa aaatcttatt tttgaataat
    10501 gcaatcaatc atgggatttt gacaccattg ggaactgaac aagtagcaga ggctggaaaa
    10561 tctattctat tcttgcttga agcaaatcct ggtccaggac ttggcgtatt acttgctttt
    10621 actttgtttg gcaaaggagc agcaaaatct tcagcaccag gagccatgat cattcacttt
    10681 ttaggcggga tccatgaaat ctattttcct tacgttatga tgaaaccgtt attattctta
    10741 tcagttatag gcggaggaat gtcaggaagt ttcattttcc aattgatgga tgctggacta
    10801 agagcgccag cttctccagg gtcgatcatt gcgattctag cgatgacacc gttcaattct
    10861 taccttcctg ttattttggg cgtgattgtt gccgcagctg tttcgtttgg tatttctgca
    10921 gtaattttga aagcggatgc gaaagataca aatgaagact tcgaaaaatc tgttcaagag
    10981 acaaaggcag ctaagcaagc ttccaaaggt gcccaaggta ttcctcaagg agctacattc
    11041 tctggcgtac aaaaaatcat ttttgcttgt gatgcaggaa tgggatcaag tgcgatgggc
    11101 gcttcgatct tgagaaaaaa agtacaggaa gcagacttgc ctcaaacggt gaccaatcaa
    11161 gcaatcagcc aactgacaga tgactcgaat acattgatcg ttactcaggt cgaactacaa
    11221 gaaagagcaa aacaaaaagc accgagcgcg cgttttgtct cagtagaaaa ctttttgaat
    11281 tcacctcgat atgatgaaat cattcaagaa ttaagcagca agcagaaaac atcagtttct
    11341 gaaattgaga atgagccagc agaagagttt ctttcagcaa acatcaaaca aatcaaagag
    11401 attctacttg tccacgatga tcgttccgga tcagcaacaa tggggatgac cgtgctcaaa
    11461 gatatattag acaagaacca tttaactatc ccgttaagaa aagtcaatat ccaagattta
    11521 aaagatgaac ctgattcact gatcgtagcc aaagaaagtt tagcggaaaa agtacagatg
    11581 gctgcacctc aatccattca tttatcagtc aacagcatgg tcaatccgca aaaatacgaa
    11641 tcgattgcac aatatttgaa acagacagct taagggagga aaacagcatg caaagtttgc
    11701 cattcgacat gatcgagctc aatcgatctt ttaaaaccaa agaagaagcg atccgctatt
    11761 gcggtcagat gcttgtagaa gcagggtgcg ttgatgagga atatatcgat gccatggtag
    11821 atagagacaa aatgttatct gtttatatgg ggaattttat cgcgattcct catggaacag
    11881 atgaagcaaa aaaatatgtg aaaaaatccg gcatctgtgt cgttcaagta ccagatggtg
    11941 tagattttgg taccgaagaa gaagaaaaga ttgcgactgt tttgttcggt attgcaggag
    12001 tcggagatga gcatttgcaa cttgtacagc aaatcgcact ttattgcagt gatatggaca
    12061 atgttgtcca gctagcagac gcgctcagca aagaagaagt aacggaaaat ctagcaattg
    12121 cttaaggaga gagaaaaatg agagcagtac attttggtgc aggaaatatc ggtcgaggat
    12181 ttattggaga ggttttggca gctaatggat ttgagattac tttcgtagat gtgaatcaca
    12241 cgatcattga tgctttaaat gaaagaaaag aatacgaaat cgaattagca gatgaatcaa
    12301 aagaaaaaat cactgtaaaa aatgtcaaag gaatcaacaa tcaaacaaat ccagaaaaag
    12361 taatccaaga aatcgctgaa gcagatttag ttactaccgc cattggcccg aatatcttac
    12421 cttttattgc tgagttgatt gcaaaaggta tccaagaaag agaaaaggaa ggaagcacaa
    12481 catctttaga tatcattgcc tgtgaaaata tgattggcgg ttcagcattt ctagaaaaag
    12541 aagtgtataa atatcttccg gaaacatcat ttactgacaa atatatcggc tttccaaatg
    12601 cagcagtcga tcgaatcgtc ccattacaac accatgaaga tcctttattc gtccaagtgg
    12661 aacctttcaa agaatgggtc attgacgata gccaaagaaa aaataaaaaa atccaattaa
    12721 aaggggtttt atatgtagat gatctagaac catatatcga acgcaaacta tttagtgtca
    12781 atactggtca tgcgactgtc gcttatacag gtgccttgtt aggttaccag accattgatg
    12841 aagcaatgca agatgcgtta gttgtggcac aattaaaatc agttttgcag gaaacaggaa
    12901 gtttgctgat tgccaaatgg gggtttgatg cagagcagca tcatgcgtat attgaaaaaa
    12961 tcattcatcg cttccaaaac aaaaatatct ctgatgcgat cacacgtgtc gctcggacac
    13021 cattacgtaa gttaggttat caagaaagat ttacacgtcc agtgagagaa ctacaagaac
    13081 ataacttgac ttgcccacat ttgacggcaa caatggggat tatttttaat tactatgatc
    13141 ctgaagatga acaaagccgt caattgcatg aaatgaagat ccatgaaaac ttggaacaat
    13201 tgattcaaga agtcacagga atcaatgatc cgaaaacaat cgggaatatc aagcaaaacg
    13261 tgaaccgtta tgccaagcaa gtcgcttaaa ataggatacg aaaaagggga atgtgacgaa
    13321 attttt
//
LOCUS       DACGMI010000078        13188 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.081, whole genome shotgun sequence.
ACCESSION   DACGMI010000078 DACGMI010000000
VERSION     DACGMI010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.081"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(220..1671)
                     /gene="cls"
                     /locus_tag="IXT46_002545"
     CDS             complement(220..1671)
                     /gene="cls"
                     /locus_tag="IXT46_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAQ4948435.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            2012..4678
                     /locus_tag="IXT46_002546"
     CDS             2012..4678
                     /locus_tag="IXT46_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4948436.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            5042..5794
                     /locus_tag="IXT46_002547"
     CDS             5042..5794
                     /locus_tag="IXT46_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4948437.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(5816..6970)
                     /locus_tag="IXT46_002548"
     CDS             complement(5816..6970)
                     /locus_tag="IXT46_002548"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAQ4948438.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            7155..9596
                     /locus_tag="IXT46_002549"
     CDS             7155..9596
                     /locus_tag="IXT46_002549"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAQ4948439.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(9926..10630)
                     /locus_tag="IXT46_002550"
     CDS             complement(9926..10630)
                     /locus_tag="IXT46_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948440.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(10817..11062)
                     /locus_tag="IXT46_002551"
     CDS             complement(10817..11062)
                     /locus_tag="IXT46_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948441.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(11079..11930)
                     /locus_tag="IXT46_002552"
     CDS             complement(11079..11930)
                     /locus_tag="IXT46_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAQ4948442.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            12096..13100
                     /locus_tag="IXT46_002553"
     CDS             12096..13100
                     /locus_tag="IXT46_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAQ4948443.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT         4209 a         2343 c         2752 g         3884 t
ORIGIN      
        1 ttttgaacac cgtttaagaa agaggtcgtg agcctgccgt ccagctccga gtcacaagga
       61 acaagttcaa aaaacagctt ctcatgtttg ttgaatattg tgacttgtga ccgaggagtt
      121 ggcaggagaa caccgtttgt tcggaagaag ggactgtgac aagatttttg tcacagtccc
      181 tttaatctta gtatattttt ctctacttga ataaaaaaat tataggattg gagaaaataa
      241 tcgagaaatt tgttgcttga ataatagcca gttagacatt tccttgactg tttcagttgt
      301 catggatgaa caatgtgtct catcttcttt gaactgagta gcaagttctt ctaaaaactc
      361 aggatcgtaa atgacagcac ttgtttcaaa attcaatcgg tagctacgaa tatcttgatt
      421 tgctgaacct accatgcaga tttcatcatc cattatcaat gtttttgcat ggaggaagcc
      481 gttctcatag acaaggattt gtacattttc cttgatcagc tgccgagcat aatattgtgt
      541 tgctcgataa ataaaaggat gatccggttt gttgggaatc atgattttca catctacacc
      601 agaggcagtt gcgattttta aagcagcaat gacactttca tcaggaacaa ggtaaggtgt
      661 ctgtatccaa acacgttttt tagcagaagt aatcaatttg ataaatgaaa gcttgatttg
      721 ttccctttcg ttattcggtc cgcttgaaac aagctggatg gatgtatcag caagcttaga
      781 ttcatctcga tctgcttttt taaagaaata attcaaatga tagccgacct ttttttcttc
      841 aggtaccgag acgttccagt ctgttaagaa gcgaagctgg agcaaagaag aagcggcacc
      901 gaaaatccgt atatgcgtat cgcgccaata gccgaatttt tttgttgtat ttacatattg
      961 attggcaata ttgaaaccac cggtataact aatctttcca tcgatcacaa cgatttttcg
     1021 gtgatcatgg taattcaatc ggaaacgaag taatgccctt tgtgaggtaa caaatgtatg
     1081 gacatgtcca ccatttttga ttagacgatt gaaatctttt gcttttgtgc catgagagcc
     1141 aaatgcatca tataatattc gaacttccac gccttctgcg gctttttctt ctaaaacatg
     1201 taagacttgc tggccgatat tatctgtcac aaatgcgtaa tattcgatat ggatcgaatg
     1261 tttggctttt tttagatctt gaagcagtga atccaatttc tcttgtccgt ctgtgagaag
     1321 agtgacagaa ttcattcttg tcagcggcat acgatttaat gaagagaaga agtcaacaaa
     1381 ttgctgtttg tctttatcgc ccatgtcagg atcgtaatgt tcaatggtat ctcctctaaa
     1441 agactgaaag ttttctaatt ctttcaagtc actttgtcgg agatagaatt ttttcttatc
     1501 cgttaatcca cgtccgaaaa ataaatataa tacaaagccc accccaggaa gggcaaacaa
     1561 tactaagagc catgcccaaa tggctgctac atctcggggt ttgatcaaaa tagccaccaa
     1621 agcaataagt gcatttaata gataaagggc ggttataata ctagatacca caaaaatgtt
     1681 cctccttaca tacaataaca ttagtatagc atgatagaag aaagaagcct accaaggtga
     1741 atatactttt cactcctttc atgaaaatgt aggtaaatcg ggctaaagta gttgcttttt
     1801 gtaggttaat aaggtaggat attagtacag ttgaatatct ccttagggga gtaaccggca
     1861 acgtttgttg cgataatatc aacagtaagt taaccaaatg gttttctggt attgtatgaa
     1921 atggtgagac ctaagacaaa tgcgtatttg tcttaggtct cttttttttc agacaggact
     1981 agggccaaga tcaaaaaatg ggggatgaaa tttggaaaac aaggaacaag cacaacaagc
     2041 ggtctataaa gaaacgatcg actcgttgat gcagcaaacg cagagctcaa ccgatggatt
     2101 gagcaccacg caagcgaagg aaaaattaga aagagatggc ttgaaccagc taaaagaaaa
     2161 gccgaagaag ccaacttgga aattgttctt agaaactttc aaagatgcaa tggttatcgt
     2221 attgctgatt gtcgcactga ttcagatggt catgggtgac tacatcgaat tcttagttat
     2281 ttttgcagta ttgatgttga attctataat cagtgttgtc caaacaaaaa aagcagaagg
     2341 ttctttagaa gcgttgaaaa acctttcagc gcccgatgct cgagtgattc gtgatggtaa
     2401 ggaaaaaacg attccggcaa acgaacttgt ggtaggagat atcgtgttgt tagacgcagg
     2461 cgattatgta cctgctgatg gacgtttact agatgcggga tcattaaaag tagatgaagg
     2521 tatgctgaca ggagagtcga cttctgcaga aaaagaagta acggatatca caagtacggt
     2581 accaatcgga gatcgtacaa atatggtatt cagtggaacg atcgtaactt acggacgcgg
     2641 taaattctta gtgacttcaa ctgggaataa tacggagatc ggacaagttg ctggcctttt
     2701 ggaatcaaca actgagcaag tcactccgtt acaacgaggt ctggataaat tcagtaaaaa
     2761 actaagtttg gctattttgg cattgtcttt attgatttta ggtatccaac tgtttcgtat
     2821 ttatcttgga gaaggtacag gagatatgac tgcagatatc gtcagcgcag tgatgtttgc
     2881 cgtagccgta gccgtagctg ctattccaga agcattacag tctatcgtaa caatcgtgtt
     2941 atctttggga acgaataaaa tggcaaaacg tcatgccatt attcggaagc ttccagcagt
     3001 tgaaacactt ggttcgacaa gtatcatctg tacagataag actggtacat tgacacaaaa
     3061 caaaatgaca gttgttgact actttttagg taatggcgat actggggatt tcacaaatga
     3121 cccttcaaaa tggacagctg acgaacgtcg cttgatcgaa atcagtgttt tagcgaatga
     3181 tgcatcgatc agtgaagacg gtactaaatt gggcgaccct acggaagtag cgtttatcga
     3241 ctttagtgaa aaattaaacc agccttatca ggaaatccga aacaactacc caagacaagc
     3301 agaacttcct tttgactcag atcgaaaatt aatgtctact ggacacacaa ttgataacaa
     3361 aaattacttg tttgttaaag gcggaccaga tatcgtcttc caacgcagta aaaaagtatt
     3421 gctaaatggt gaagtcgttc cgatgacgga tgaattgatg aaaaaattcc aagagcaaaa
     3481 tgaagctttt tcaacacgcg cattacgtgt actagctttt gcttaccgtc cacttgataa
     3541 ttttgattta tcatttgaag atgaagacga tttgatcctt gttggtttgc ttgctatgat
     3601 cgatcctcca cgtgctgaag tgactcaggc ggtaacagaa gcaagaagtg caggaatcaa
     3661 aacaatcatg attactggtg accacaaaac aacagctgtt gctatcgcaa aacaaatcgg
     3721 gatttttgaa gaaggaaacc tggctttgac cgggacggaa ctagatgaat tgacagaaga
     3781 tcaactaaac gaagttttag aaaaagtcac tgtttatgca cgtgtttcac ctgagaataa
     3841 aattcgtatc gttcgtgctt ggcaaaataa aggtcatatc tcagctatga caggtgatgg
     3901 tgtaaatgac gcaccagcat tgaaacaagc agacatcgga attgctatgg gaacgggtac
     3961 agatgtggca aaagatgcag cagcgatggt attgacggat gataactttg cttctattgt
     4021 cagcgcagta gaagtaggac gtaatgtgtt tgataatatc aagaaagcta tttcttatct
     4081 atttgcagga aatttaggtg cgatcattgc gatcatcttt gccttagttg ctgactggtc
     4141 caatccattt acagcattac aactgttgtt catcaattta gtcaatgatt cactgccagc
     4201 aattgcatta ggtacagaaa aagctgaacc tgctacgatg aaccgcccgc caagagatcc
     4261 aaattcagga atctttacgg acaaaacatt gatttctgta acgtatcgtg gtgtgctgat
     4321 tgggattgct gttatctttg ctcaatggct tggcatgcag cattcacctg aattcggtgt
     4381 agccatgtca ttttcaacat tgatttggtg tcggacattg caaacattcc cagcacgttc
     4441 aaacacacaa acagctatcc aagcagggtt cttctctaac agaagtgtct tactagctgt
     4501 agttgtatgt agcgcgcttt actgcttaac aatgatccca ggactgaaag aagtcttctc
     4561 tatcccatca gcatttggat tgacagaagt ctttacatgt atgggaatcg cacttgtgac
     4621 aattgttttg atggaaatca ctaaattgat cattgtacga gtacaaggaa ataaataaaa
     4681 cgaatcaacg aggttgtgag cctgccgttt aattctgagt cacaaggtgc aatttcaaca
     4741 aacagcttct catgtttgtt gaatattgtg acttgtgacc gaagagttgg caggagaaca
     4801 ccgtttaagg aagaagttgt aaaatcagca ttttgagcta atactgaggg tcatctgatt
     4861 ggacactgtt tattcggaaa gagggacttt gacacgactt tggtcacagt cccttttttt
     4921 atttatgata gacggaaagc caatcatttt attattcatc aaaagagata gaatagataa
     4981 aagaggagaa tgatttattc cgaaaagtga aaacatataa caaaaaatta gaggaaatca
     5041 aatgaatgaa aaagaatggg atgaatttgc tgaagaatat tatgaaatcc agcaagaatc
     5101 gcaagtaact attgctgaag atgtaaaaaa ttatctgaaa acggagaaag tcctgcctgc
     5161 tgaaacagca gcagacgttg ctggaggatc tggcagattt ctttccttag caaaagaaat
     5221 taatcgctat gatttgatcg atttttcttc aggaatgcta gaaaatgcaa aaaaagaagc
     5281 agaaaaaaat gagttgccaa atgtttcctt tatcaaacag tcgttagaag aatttatcca
     5341 atcaaatgag acatatgaaa tggtttttac agcagcaaat ccagcattgg tacatcttat
     5401 tcaattagaa aaattgatga aaaagtcaag caaatggtgc gtgataatca gagtagtgga
     5461 atcaatcgat gatgtttttt atcctatcga aaagcaacta ggaatgatag aagaagatcc
     5521 taatacatcg ccagttgtaa tggatcaatt tgaaacatac ttaattgatg aaggattcaa
     5581 agtgaagaaa aaagatttta cttattttac acaggaatca attactgaag aattgatgaa
     5641 gctatactat gacgcgtacg caaaagatcc tgttgtgacc aggtacattc gcaaactatt
     5701 cagtgaaaaa cgagaaatcc ttagtacgac taagctgacc tatagactgc tcctttggtc
     5761 cgcagataaa aaaagaacct ttcacgactc gtgaagggtt ctttttatga ttttattata
     5821 ttttgtagta acgaatatca ttttcgatct ttgtaatcga aaaaggtaca tctgaagtat
     5881 attctgcaca ttctccgtgt tcaggaagcg tctcactgaa aatcgtttca tattcgtcaa
     5941 cagtgatccg tgttcgagaa tctagcatct cttgatgaga ttgtgcgaag agatattctt
     6001 gatagttttc ttccagataa cctgtaaaaa attcacttac tgcaccagaa ccgtagctga
     6061 atagaccgat gcgatctcct ggctgtagtg atttcgaatt ttccagtaga gaagttagcc
     6121 ccaggtataa tgaaccagtg taaagattac cgattcgtcg gctgtaacgg atgctttctt
     6181 catagcgagc cataagacgt tcctgatttt cttcgtctgt ttggtctaat acgctttgca
     6241 atgccttttt tcccatctta gtatacggaa tatggaaagc aatcgcctga taatcttcga
     6301 gtcctcgacc cgacaattct ttatgtcgat tccaaacttt ttggaatgat tcgatatacg
     6361 tagaattaga taaaggacca tcaacaacag gaaattcgct ataatctgga cgccagaaat
     6421 catagatatc ttctgtcaga aatacgctgt cgtcttcaat cgataaaata cgcgggtttt
     6481 gagtgatcat catcgcaaca gcaccgacac cttgcgtcac ttcaccaccg cttgccaagc
     6541 cgtaacgagc aatatcactt gctatgacta gtacttttcg ttctggatga tttttgacat
     6601 attctttcgc catgtgcaaa gctgcggtgc caccgtagca agcctctttt acttcaaaag
     6661 aacgagcaaa agattggatt ttcagtaaat ggtggataat taccgcactc gcttttgaat
     6721 gatcaatccc ggattctgtt ccgacgatga ccatgtcgat tagctcacgg tctttttctg
     6781 ttacgatttt gctggcagca tttgctccta gtgtaatgat gtcttcattt gcacgattga
     6841 ctgccatttg gtcttgacca atccctatat ggtattttgc aggatcatcc ccacggcttt
     6901 ctgccaactc tgtcatatct aaatataaat taggaataaa aaaggaaaga cgatcaatcc
     6961 ctattttcat ttcaacacct ctttacttat gataaaaaac ttactttact aaggtatcat
     7021 aaaaagatta aaagaaatat aaaaaagaga atatttaagg attgttaaaa tttaatctta
     7081 gaaaaaaata actggaacaa gagctatttg tttttacagc aaagaatggt atatttttgt
     7141 aggaggtggc ttacttgaaa gaagtcgtta tgatagatgc tgcaagaacg ccgataggaa
     7201 agtatcgcgg aagtttaagt ccatttactg cagttgaatt aggcacactt gtgactaaag
     7261 gattattaga taaaacaaaa ctgaaaaaag ataaaatcga tcaagtaata tttggaaatg
     7321 tcctgcaagc tggtaatggt caaaatgttg ccagacagat tgctttgaac agcggtctcc
     7381 ctgtagatgt cccagcaatg acgatcaatg aagtttgcgg atctggtatg aaagcagtga
     7441 tcttagcacg ccagctgatc caattaggtg aagcagaact tgtgatagcc ggcggaacag
     7501 agagtatgtc acaagcacct atgctgaaac agtatcagtc agaaacaaat gaatatggtg
     7561 aaccaatttc cagtatggtc aacgacggat tgactgacgc attttcaaat gcacatatgg
     7621 gattaaccgc agagaatgtt gcaacacaat tttctgtgag cagagaagag caggatcgct
     7681 atgccttgtc gtcccagttg aaagcagcac atgctgtcga agccggtgta ttttctgagg
     7741 agatcatccc agtcaagatt tctgatgaag acgtgttatc tgaggatgaa gcagttcgtg
     7801 gaaatagtac attggaaaaa ctgggcacgt tacgtacagt attctcagaa gaaggaactg
     7861 taacagcagg aaatgcttcc ccgttgaatg acggtgcctc tgtggtgatc cttgcatcca
     7921 aagaatacgc agaaaataat aatctgcctt atttagcaac catcaaagaa gtagcggagg
     7981 tcggtattga cccaagtatc atgggaatcg ctccaatcaa agccattcaa aaattgacag
     8041 atagatcagg aatgaattta tcaacaatcg atctttttga gatcaatgaa gcatttgcag
     8101 cttcttctat cgtagttagc caagaactgc agttagatga agaaaaggtc aatatatatg
     8161 gaggagcaat cgcattaggc catccaattg gtgcaagcgg tgcacgtatc ttgactacat
     8221 tagcttacgg attgcttcgt gaacagaaga gatacggtat tgcttcatta tgtattggtg
     8281 gaggtttagg cttggcagtc ttgttagaag cgaatatgga gcaaacacat aaggatgtgc
     8341 aaaaaaaaaa gttttatcag cttacgccat ctgaacggcg cagtcaatta atagaaaaaa
     8401 atgtattgac acaagaaact gcgttgattt ttcaggaaca aacactttct gaagagctct
     8461 ccgatcacat gatcgaaaac caagtgagtg aagtggaaat cccaatgggg atcgcgcaga
     8521 attttcaaat caatggcaag aaaaaatgga ttccgatggc aacagaggaa ccatctgtca
     8581 ttgcagctgc aagtaatggt gcaaaaatct gtggaaatat ctgcgcagaa acacctcagc
     8641 ggctgatgcg agggcaaatc gttctatcag gaaaatcgga gtatcaagca gtgatcaatg
     8701 cagttaatca tcgaaaagaa gagctgattc tttgtgcaaa tgaaagttat ccttcaatcg
     8761 tgaaacgcgg gggcggtgtt caagatatct ctactcggga attcatgggg agtttccatg
     8821 catacttatc tattgatttt ttagtggatg taaaagatgc aatgggcgct aacatgatca
     8881 actcgattct tgagagtgtg gcaaacaagt tacgggagtg gttccctgaa gaagagattc
     8941 tattcagtat tttaagtaat tttgctacag aatcattggc ttctgcctgt tgtgaaatcc
     9001 cattcgaacg cttagggaga aacaaagaaa tcggtgaaca aattgccaaa aaaatccaac
     9061 aggcagggga atatgcgaag cttgaccctt accgtgcagc aacgcacaac aaagggatca
     9121 tgaatggtat agaagctgta gtggcagcta caggaaatga tacacgtgcg gttagcgctt
     9181 cgatccacgc ctacgcggca agaaatggat tataccaagg attaacagac tggcagatca
     9241 aaggggataa actagttgga aaactaacgg tgcctttggc tgttgccaca gtaggcggag
     9301 cttccaatat cctgccaaaa gcaaaagcat ctttagctat gttagatatt gattcagcca
     9361 aggaactagc acaagtaatt gctgcagtag ggttagctca aaacctggct gctttgcgtg
     9421 cattagttac agaaggaatc caaaaaggcc acatgggact tcaagctcgt tcattagcga
     9481 tctcaattgg ggctattggt gaggaaatcg agcaagttgc gaaaaaatta cgtgaagcag
     9541 aaaagatgaa ccagcagaca gctatacaaa tattggaaaa aatccgggaa aaataaaaaa
     9601 gcaatatctt tagaagaata aagcaagatt tacagttatt ttatttactg cagatcttgc
     9661 ttttttctct atcagaaaat atgtttatta ttagaatttt ttatagttaa ggttaggcat
     9721 cttaagaaat caggcaactc caagatatct tcaggtagaa gagaagtcgc ctaacattgt
     9781 aggatcatag gtgatttgtt ggacaggtca agctgatatt tgagcctgat gttagaagga
     9841 atttcttttt acttgctgta gaaattatta tatgactaaa aaggctggga ttttaaatcc
     9901 cagcctttta tgacaaatag aatttttatc gatcagtaat cgctgtcgct gcaaattgtt
     9961 cgatcaaagg aatcaaagtc aatttgactt tgtatttccg ttcgagtgct ttttcgataa
    10021 cgaactcatt ttcagtagtc atagaaatag ttgctaattt acgaggttca tcagcatttt
    10081 tttcattaat aactacttca tgttcatttt gttctgtgta aaatttagga tactcagcaa
    10141 cggcttttga aaaatcagca aaacttaaag cggcattcgt atcagttgag cgtgtatttt
    10201 cagttgtgtc cgcttttggt ttttccgttt tttcttctgg cacactgact gtttcttctg
    10261 taactggtgt cgcaacagct tgcgcagttg gttcatcgtt tttcaatcgt tgatcattcc
    10321 agtaagacac gatttcaata agaagattgt cacggaatcg ttcgaaaatc ccgttttctc
    10381 ctgaacgaat tctctttaat acagtattga agttgtcatc gattggcacg ttgatccgtg
    10441 tatcttcatt tgttttccca gctaatccga tcgttaagat ttgacggttt ttgggatcaa
    10501 gcatgacttg taacggcaaa ccataacgtc gcaagctctc ttcttctaga gaacggaata
    10561 attgtcctct tacaccatcc aatgaaggac ggaattgatt taataatttt tgtttctgtt
    10621 ttttcttcat atgttctctc cttcgctcat accctttcga ttataagaaa aaaacagcca
    10681 aatgaaaagg agtaatgcaa aaaaacttgc gtatacgcaa attacaacag aaaaatttgc
    10741 gtattttccc gttttttgaa agaaaaataa aaaatggaac ggattatgta tatatacata
    10801 atccgttcca ttctttctat tttttcggta tcaaggcaaa aacaggtagt tcaggtgaat
    10861 aaatgacttc atgttcgtgc cagggtttga ccattagcga atgatcgaac cgttttttca
    10921 gttcttcgat gatttgatca tgtgtccagt ttcttgcagg aaaatgttgg attttctctg
    10981 catcgatcaa aaagacaaaa tcggaatgaa aagtctgggt aacttcttcc gagagagaat
    11041 tcaagcgttc gattggatcc ataaaatcac ctttcgactt aaaattgggt agtatctggg
    11101 tcttttgctt tgccgactac accatctaac tgatcgattt gtttcatttc ttcttctgtt
    11161 aattcaaaat caaataattc agtattttct ttgattctgc ttggtgtcac tgacttagga
    11221 agaggaagga attcgtgttg cagcgaccaa cgcaaagcaa cttgtgcaat cgtcttgtca
    11281 tgtgcttcag cgatttgttt catttcaggc acatcgaaga ttttaccagt gcctaatgga
    11341 ctatatgctt cgaggatcat atcatgtttt tttgcatact caactacagt tgtctgtaat
    11401 tcgcctggtg caaggaaaac ttgattgacc atcggcataa tttttgctgt ttttgctagt
    11461 gtatctagat ggtggggtaa gaaattgctc acaccgattg ctttgatttt acctgcttca
    11521 tacagttctt caaatgctcg ccatgtatct gcatttgctt gttcccaatt atcacgaaaa
    11581 gcaacagggt ttggccagtg gatcaaaaac agatctaaat aatctgtttg gagcttcttc
    11641 aatgattctt caaaagaaga catcacaagt tcatagctgt ggtttgcatt ccataatttt
    11701 gttgtcaaga atatctcttc tctaggaatt ccactttcct taatcgcttg gccgacgctt
    11761 tcttcattct tgtatccttg ggcagtatcg atatggcgat aacctgcagc cagcgcttct
    11821 ttaacagagg aaacagcgac atccccatca ggtgtttgcc atgtgccgaa tcctactacc
    11881 gggatttcgt aaccatttga tagacgataa gtgcttgtta atgaattcat actttcagct
    11941 ccttttttat tcgttcaact ataagtgtag cgcatttttc gaaaaaaaga atccattttg
    12001 tttctactct tgaaattttt gtttaaaaga aaatgatttt gattctggta tttttgattt
    12061 tttttccgta aactaagaca gaagggaatg agaaaatgga tatctattta aaaaaagcaa
    12121 ttctgcatat tattgacaga gaaactggtt ctccagtctt ttcacaaaaa gagctggatc
    12181 tgacaaaaga atatattcgt gattttcttc aaaagaagat ccaaaaaatc tcttctgctc
    12241 aaacaaaaac tggacaacta gcagaagaaa gcatgatcgt tgaatcactt aaaatcgctc
    12301 aagaaaattt tgtggaagca agtgaagcaa tcgttcagcg gtggttcgat atctaccaag
    12361 aaagtgaaga agcacctagt gcagatgtat ttgttgtctt gtatgaatta gatacagtga
    12421 tgtacttatc tttattgaaa gtcaattatc gtgaggctta cactcacttt gttgaagcag
    12481 acgaagcagg gatcgacaac cgcttgattt tgaatcgagc aattctaggg gcgaaaacac
    12541 aaaaagcaga tgaagcattc gctgtgaatt tgactgattg gacctacgaa ttaattgaaa
    12601 aaaaatatga gttttctggc aaaaaagagc tttatttttc tggaagagtg atcgaaagtg
    12661 ttcctgcacc ttctttagaa gaaaatgtaa aagtgatcca aaaagtagcc aagcatcttg
    12721 gaaaaaaatt tgagacagaa gaatttgata tcatggctga tttgaaagaa gctgtctatg
    12781 atacgataga agaaaaaggt cggttggatc atgagatgat tgcggaaaaa gtcttcaagg
    12841 aaaacatcac ggcaaaaatg gcttttaaag aagaagtaca agagcaagga tttgtcccag
    12901 aagcacctcc tgtaaaagaa gtacaagaaa tttctgagaa aaaatttgga aaacaaaaat
    12961 tcaagctatc aaacgggatc gaactgatcg taccagtaga tgtatatcgc aacccagatt
    13021 tgattgaatt tgtgaataat ccggatggta cgatatccgt gatgatcaaa aatgtggatg
    13081 aagtattgaa tcgtttataa aaatgactag aatattaggt gttcaagtac cagtgatcag
    13141 ttaaatgaat tgtgtcaaga gaaggatcgg aaaagacgaa tataacaa
//
LOCUS       DACGMI010000079        13085 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.082, whole genome shotgun sequence.
ACCESSION   DACGMI010000079 DACGMI010000000
VERSION     DACGMI010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.082"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(79..2199)
                     /locus_tag="IXT46_002554"
     CDS             complement(79..2199)
                     /locus_tag="IXT46_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAQ4948444.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2429..3607
                     /locus_tag="IXT46_002555"
     CDS             2429..3607
                     /locus_tag="IXT46_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAQ4948445.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3623..4381
                     /gene="aroD"
                     /locus_tag="IXT46_002556"
     CDS             3623..4381
                     /gene="aroD"
                     /locus_tag="IXT46_002556"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAQ4948446.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4404..4889
                     /gene="ybaK"
                     /locus_tag="IXT46_002557"
     CDS             4404..4889
                     /gene="ybaK"
                     /locus_tag="IXT46_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAQ4948447.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4960..6213)
                     /locus_tag="IXT46_002558"
     CDS             complement(4960..6213)
                     /locus_tag="IXT46_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4948448.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6329..7678
                     /gene="gdhA"
                     /locus_tag="IXT46_002559"
     CDS             6329..7678
                     /gene="gdhA"
                     /locus_tag="IXT46_002559"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAQ4948449.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7790..9136
                     /locus_tag="IXT46_002560"
     CDS             7790..9136
                     /locus_tag="IXT46_002560"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAQ4948450.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9444..9830)
                     /locus_tag="IXT46_002561"
     CDS             complement(9444..9830)
                     /locus_tag="IXT46_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4948451.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            10709..10921
                     /locus_tag="IXT46_002562"
     CDS             10709..10921
                     /locus_tag="IXT46_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948452.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11199..12998)
                     /locus_tag="IXT46_002563"
     CDS             complement(11199..12998)
                     /locus_tag="IXT46_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAQ4948453.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4291 a         2353 c         2577 g         3864 t
ORIGIN      
        1 ttattctaag atttctcttt accaacatca tttgacaaag agcctaattt tgtcgctgct
       61 ccttttaaat ttattttatc attcggaaga acttgtggtc gttccgtgaa gttcttggta
      121 cgtttgcgtt ttataaagat caacagttga ttgtcccttg tgttcactaa agacactagt
      181 tgacttgtca ccaagagatt tttcagcttc ttttaatttc tctaagccat tcttgtagtc
      241 ataatcactg gtatcaattg ggtctaatcc actattcgta tagaaccgaa gaagatcacc
      301 attattgatt tggtcagaaa cagctaactg tttatcaact ttttctttca gtgaatcaat
      361 ttcattctgt acttcctcag taggttcagt aatagcttca ccagtttcgt tactatagat
      421 cgtaccaccg tagtaagtat attttggtgt aacaaaatca ccatcacgga aagaaacaag
      481 ctgttcatga tctttcgaga atagatcttg tcctaactga atataatttt ttgtatctac
      541 acctagtaag tgaagtaatg taggcaaggc atcaacttgt ccgccgtaag tgtgattgat
      601 tccgccctgt gtttgtccag ggatatggat catataaggg acacgctgca tttgtgcatt
      661 gtcgtagttt gtccaagtag aacttgtttt tccaactaat tcagctagat ttttatttct
      721 tgaattcgag acaccgtaat ggtcaccgta aaggacgatg actgaattat catacaagcc
      781 gctttctttc aaataattga agaattcttg tacggcggta tctaaataat tggctgtcgc
      841 aaagtaaccg ttgatcgttt catcatttgt attggctaac gggaatcctg cttcgtcatt
      901 ggtgaatttt gaataaggat aatggttaga tacagcaatg aattttgaat aaaatggttg
      961 ttgcagacgt tccaagtatt gtacggattg ttggaaaaat ggtttatcat gcaacccgta
     1021 ttggaacgaa ttgtcatcat taacatcata ataagaagaa tcaaagaaat aatcatatcc
     1081 taaattcttg tatgtctcgt ttcgattcca gaatgtacca gcgttcccat ggaataccgc
     1141 actagtgtaa ccttgtgttt gacttaaaat atcaggtgca gcttggaaag tattttttcc
     1201 gcctaattgt gtgaacaagg agccttgatt caagccaaac aatgaatttt ccatcagcgt
     1261 ttccgcatcg cttgtttttc ctgcttttac ttgatggaaa aagttgtcaa aactgaacgt
     1321 gctgttgctg tggtaaagac tattgatgaa aggtgtaact tcaagctgga gaccattctc
     1381 atctgtcaat ttataatcga tcaggaattg ctggaagctt tctaaatgga tataaatcac
     1441 attttttcct ttagcgagcc cgaacaaatc atcatttggt gctgcataat gttcttttac
     1501 ataattttct acttctttca tatcattggg acttgcttct gcccgcactt ggtttgtctg
     1561 gtaagtttga acaccgtcat aaaccatgaa agcattcaag ccaagatatt tgaccaaata
     1621 atcacgagag aatgttcgag tcagcaattc tggacgatca gcttccgcca taaaaagatt
     1681 tcctgagaaa atcataactg ctaatgtaga gatcgcaaaa gccattcttg ctcggatcgg
     1741 gcgagggtcc aacttgattt tttttgcaat cagcagaaca gtcaagataa taaaatcgat
     1801 ccaatagatc acatcatatg ggcgaaacag tcgaatggca ctttctccca gaccactcgc
     1861 tactttccca gcacctaaaa tcgtgttgat cgtaatgaag tccgtgaatt ctcgataata
     1921 agtgacattc gaaaaaacaa gcaatgtcaa aagaaaataa atgaccatca tcgtgatata
     1981 agcaactcta gggcgtctga tataaagagc aattccaagt aataacaatg tagttgcaat
     2041 agggttgata aacaagataa agtattgaat gccactttcg attccgagat ggaaatcaac
     2101 taaataggca aaaatcgttt tcaaccaaag taaaacaact agtaaagaaa aaaatccgag
     2161 cctcttattc aaaaaggcag gtgtttttat acatttcaag ataatcttcc tttctgcact
     2221 tcttaatcac agaagtgtca tgaaaccatg ttacacagct cacttattct catttatttt
     2281 actagtatga caatatagtg tcaattgaaa ccagaagttt atgctgtttc attaaggttt
     2341 tctttaagct tcatgaaaaa atgagcagta agacaagtcc tatgtttttt gttatacttg
     2401 ggaagagaaa gctaaagcag gtgaaggaat gaaagtaaaa gtaaaaaaaa gagcaagcaa
     2461 tcgattgaaa aaaggatatc cactgatcca aaaagaagac cttgctcatc cccaaaaaga
     2521 aaccacgcaa tgggtggaat tagttgattc gcaaaaccaa tttatcgcaa aaggatatct
     2581 aggaaagcag aataagggaa tcggttgggt attgagccag cagaacatcc catttgatca
     2641 atcttttttt gaagaatttt ttgtgaagtc aaaagaaaaa agaactttct ttttttcaga
     2701 tgattctact accgcttttc gtatattcaa tggagaagga gacgggatcg gcggtctgat
     2761 tgttgattat tatgcaggtt atgctgtttt ttcttggtat aacgaaacgt tatatgcaca
     2821 tcgtgaatta ttgattcaag cttttcgtga aatctacccg gaaatcgtag gaggctatga
     2881 gaaaattcga tttgaatcag taaatctgcc tgagagccag ttcatttacg gaaaagaggc
     2941 accggaaccc ttgatcgtaa aagaaaacgg agtaaaattt gccgtttatt taaatgaagg
     3001 attaatgact gggatctttt tagaccaaaa agaagtacgg ggatcattag cagaaggttt
     3061 cgcttctggg aaaacagttt tgaacatgtt tagttatacc ggcgcctttt ctgttgctgc
     3121 cgcaatggga ggggcaatcg aaacaacaag tgtcgatcta gcaaaacgca gtttaaaaaa
     3181 aacacaggaa cagtttgaag tgaatggttt ggatgtcgat cagcaaaaaa tcattgttat
     3241 ggacgtattc gagtatttca aatacgccaa aagaaaacaa tttttatatg acatgattgt
     3301 attggatcca ccaagttttg ccagaaataa gaaaaaagtc tttcgcgtag caaaagatta
     3361 tggggaactg gtcaaggata gtctggatat tttagcagaa gacgggatac ttattgcgtc
     3421 tacaaatgct gcgaatgtct cgatagaaca attccaaaca atgattgaag aggaattcca
     3481 tgccaaaaat gtttcttttg aacaacttgc tttatatcgt ctgccaaaag atttccagac
     3541 gacggatacc tttttagaag gcaattatct gaaagtgttt gtttatcaaa ttaaaaataa
     3601 ccattagaag gagcgatgca gaatggtttg ggtaaaggga ttgaatatag gaagcggtag
     3661 accaaagatt tgtgcgcctc ttatcggggc cgtccgagag gaagtattac gtgaagcagt
     3721 tcttgcacgt gaagcagggg ccgatttagt cgaatggcga gtcgatcatt atcgtgaagt
     3781 tttttctttt gatgaagtag cagaaacatt ggttcttatc catgagatgc ttgatggact
     3841 gccgttatta tttacgtttc gtaccttagc tgaaggcgga gaacaagaca tatcgatccg
     3901 tcagtatcgc gacctttatg aacatgtgat acacacagga ttagtagata tggtcgatat
     3961 cgagttgttc aaagtagaaa gtctaggaaa aagactgata gaggaaatca agtctttaaa
     4021 cattccttta attatcagta gtcatgattt taaagaaaca ccagcagacc ctgtcttgct
     4081 ttaccgattg aatgttatgg aacattttgg agccgatatc ggaaaactgg cagtaactcc
     4141 caataatgaa cgagatgttt tgcggttgat ggagttgact agacgggcaa atgcttttgt
     4201 ctccatgcct attattacga tgtccatggg aaatcttggt aaaatttctc gtctggctgg
     4261 cggaacgacg ggttccgtta tgacatttgg ttccttaagc agcgattcta cttctgctcc
     4321 aggacaatta ccggtcaaag cattgaagca aattattcaa ttattaaatg aaccgttgta
     4381 gaacaagttt gaggtgatat tttttggcaa agaaaaaaat agtaaaaacg aatgcaatcc
     4441 gtatggtcga acaaaaaaag attccctata cagagcacga atatgagtgg gacgaaagcc
     4501 acctaagtgc gtcatcggtc gctgaacagc ttccagaaag ccaatctcat atatttaaaa
     4561 cactggttgc tgtgggcaat gtgacggggc ctcttgttgc tgtgataccg ggagaagccg
     4621 aattgaatct aaaaaaatta gcaaaagttt cagggaataa aaaagtagaa atgctccatt
     4681 taaaagattt ggaagcaacg accggataca tacgtggtgg ctgctcgcct ataggtatga
     4741 aaaaactatt tcctacttat ttagatcaaa ttgcagaaag ctatgaacaa atcattgtct
     4801 cggctggcag aagagggcta cagatggagt tagcacctca agatatctgt gcattaacga
     4861 gcggacaatt tgcagatata aaacaataaa tcatacgtat aaaagaaaga aggaggccgg
     4921 gatgttgttt gtccagtctc cttctttctt ttttatacat tatgctcttt gcccggcatt
     4981 cattcctgct acatgccctg tagcgaaagc cgctgtgata ttaaagccgc cagtataacc
     5041 attgacatcc agtaattctc ccgcaaaata cagaccatca atgattttac tctccaatgt
     5101 tttaggataa atttccttta gagaaacccc tccgccagtt acaaatgatt tctcaatagg
     5161 aaaagttttg ttgattgata gcttaaactc tttgcatagt tgaacaaaat cttgaatttg
     5221 tttttgagag gcttgttgtc ctgtcagatg atccatttca agccgctcaa gaaagaaaac
     5281 taacaatcgc tcaggcaata taccatgcca agcattgacc aagttctttt tggttgcttt
     5341 acttttttct gtcaatatat gaataagctc ttgtttggtt tgtgtaggga aacaatccag
     5401 agaaagtgtc actggttctc ccgttttctc taattcttta ttgacaaaac ttgaacaacg
     5461 cagtgcagcc ggaccagaaa taccgaaatg ggtgaaaagt aaatccatcg tatgttcagt
     5521 caatacacga ccttttttat ttaaaacgcg taaagtgatg tcttgtaaag aaagcccttg
     5581 aagtgttttc tcctgaatat acggttcatc cgatatcaag ggggactctg tcgcataaag
     5641 aggcgtcacc gtgtgaccca ctcgcttcac gatcttgtac ccatctccag tagaaccagt
     5701 agatggataa gtccgtccac cagttgttaa gataatggca ggagcatgga actcttcgaa
     5761 ttccgtgcgt ataccgtaaa ttttatgttc tttgtggatc aatttctcta ctcgagtaga
     5821 gaatagaagc gtcacatcta gttctttcag acgattgagc aatgcttcga taatcgtttt
     5881 tgatttattt gttacaggaa acatccgtcc atgatcctct tcttttaaat gtacgccttg
     5941 tgattcaaag aagttcatga tatcgaaatt attccattgc gcaaacgtac tatataaaaa
     6001 ctttccattt ccaggaatat gtgcaatcaa atcatcaaca ggacgattgt tcgtaacatt
     6061 gcaccgacca ccacctgtca tcagtagttt ttttcctgct tttttgtttt tttcgatcaa
     6121 gagtacgcgt gcgccttgtt cagctgcact gatcgctgcc atcatcccgc ttgttccagc
     6181 gccgactacg atcacatcat acagtttttc cattccctca cctcaaggaa agtgtagcat
     6241 atctgaagaa agaaaacaga aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga
     6301 gggaagataa gcaaaggagc gtggaacgat gacaaacgca acagaatatg ttcaagcaat
     6361 tcaagaaaag ctacatcaaa aggatcaagg gcaagaagaa tttttacaag caatcgatga
     6421 attcatgccc acggttatgt cttttttgga cactcatccc gaatatatcg aaaagaatat
     6481 cttagaactt ttaacggaac cagaaagagt tattcaattt cgagtgcctt ggcaagatga
     6541 tgaaggaaac tggcgagtaa atagagggta ccgtatccaa tacaactcag ctatcggccc
     6601 ttataaaggt ggattgcgct tccatcctag tgtcaatcta agtatcttga aatttttggc
     6661 ttttgaacag attttcaaga atagtttaac cggtctgcca atcggtggag gaaaaggcgg
     6721 aagtgacttc gatcctaaag gaaaatctga taatgagatc atgcgttttt gtcaaagttt
     6781 catgctggaa ttgtcaaaac atatcggccc atcgattgat gttcctgcgg gagatatcgg
     6841 tgtaggagct agagaaatcg gctatttgtt cggcgaatat aaacgattga aaaaatatga
     6901 tactggtgtg ttgacaggta aacctttgga tttttgggga agtaagatac gtacggaagc
     6961 tactggttat ggattagtgt attatgtcaa acatctattg aacgaagaaa aagattcatt
     7021 taatcaaaaa acagtttttg tttccggaag cgggaatgta gccatttatg caatcgaaaa
     7081 agtgcaagag ctaggcggga aagttgttac atgttcagat tctagcgggt acatctatga
     7141 tccagaagga atagatgtga aactattgaa agaagtcaaa gaaatcaata gacaacgttt
     7201 gacggaatac gcaaaccaac gtccttctgc tatttatcat gctggagaat ctgtttggac
     7261 attgaaagaa aaagcggata tcgctttgcc atgtgctact caaaatgaaa tagacgaaag
     7321 cttggccgaa atcttagtag aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc
     7381 atgtacagta aaagctgttt ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa
     7441 agctgctaat gctggaggag tagcagtatc tgctttagaa atgagtcaga acgcccagcg
     7501 attgacttgg gaaagagagc aagtggatga gcagctggat caaatcatgg aaacgattta
     7561 ccatacgtgt cgccaaacag cagccgagta cggcgacgaa aaaaatctgc ttcttggagc
     7621 aaatgttgct ggatttgaaa aagttgccaa agcaatggca gcagaaggtt tagtttgaaa
     7681 aatgaaactt tcttggaaat attgtcagca ttttgtttat ttgcttgaaa aataataaaa
     7741 aaaaacgtaa agtattacct gtagagtaaa cctataagga ggagaacaaa tggcacacat
     7801 tcattttgac tattcaaaag tagcaccgtt tgtcaacgaa caagagttag ggtacatgca
     7861 aagccaagta acagcagccc acaacgaatt acgggaaggt actggcgcag gaagcgactt
     7921 ccgcggctgg atcgatttac caacgaacta tgacaaagaa gaatttgcac gtatcaaaga
     7981 agcagctaaa aaaatccaat ctgattctga agtattagtt gttatcggta tcggtggttc
     8041 ttatttaggc gctcgtgcag cgatcgactt cttgaatcac acattcttca atttattaga
     8101 tagcaacaca agaaaagcac cacaaatctt ctttgccgga aattcaatca gctcaacata
     8161 tattgctgac ttgatcgaag taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa
     8221 atctggaaca actactgaac cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa
     8281 gaaatatgga caagaagaag caaacaaacg tatctacgct acaacagata aagcaaaagg
     8341 tgcagttaaa gtagaagcag atgcagaagg ttgggaaact ttcgtgattc ctgatgacat
     8401 cggcggacgt ttctctgtat taactgctgt tggtttgtta ccaatcgctg ttagtggtgc
     8461 agatatcgat gcattgatgc aaggtgccgc tgatgcaagc aaagcatact caagcgacaa
     8521 actagaagaa aacgaagctt accaatacgc agcaatgcgc aacattcttt accgtaaagg
     8581 caaagtaact gagttgttga tcaactatga accaggaatg caatacttct cagaatggtg
     8641 gaaacaattg tatggtgaat ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc
     8701 aaacttctca actgatttgc actctttagg acaattcatc caagaaggac gtcgcaatat
     8761 ttttgaaaca gttgtgaagg ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc
     8821 agaagattta gacggtctag gctacttgca aggaaaagaa gtggacttcg taaatacaaa
     8881 agcatttgaa ggaacattgc ttgctcatac agacggtgac gtgcctaact tgctagtcaa
     8941 aattccagaa atggatgctt atacattggg ttatacaatg tacttctttg aaattgctgt
     9001 aggtatttca ggttacttga atggaatcaa cccattcgac caaccaggtg tagaagctta
     9061 caagaaaaac atgttcgcac ttctaggcaa accgggcttt gaagatcttg ctaaagaatt
     9121 gaacgaacgc ctgtaagata agggtttttc gctagattta aataatcagt gatagaaaca
     9181 tgttcgcttt aaaatgaaaa ctggtaccca tttaggtact caaacatact gcatcgttta
     9241 ttcagaataa ggggctgtga caagacgttt gtcacagtcc cttgtttgta tagaaatcga
     9301 ttgattgcct tgctctttag tttgttttag gactttaaga acagtgaggc tgacttcgaa
     9361 ggttaattct gtttttttgt tttctagaat cagtaagcaa aaaagcactc acttcgagtg
     9421 cttttttgcg atatattctt agcttaagat aggcctaatt tttcttttac agatgagggt
     9481 accttatcgc tggtaattac ttttttctct atgatccgct tttcgcttgc tttcaactgc
     9541 aagatcgttc cttcggtgta agcagaacca ttggcagagt caccagaagt aatgacatcg
     9601 aaatctaact gtcttttttc accgttttca gcataagcat ctacgttgta tttaaaacct
     9661 cttccaatta cttccccatt atctgctttg atatcagttt ctgcaggcat tggagctttg
     9721 actaccgcat aataatcttt acctacataa gtagactgat agtagtccca acctttccat
     9781 cctataaaag caatcaatat gataacgatc aaccctaaaa tttttttcat gaaagatctc
     9841 cttttttatt tttattatat taaatattat acagataata acggaatatt atcatcgaaa
     9901 cagctaacaa aattgtcata aaaaacgaga tggttgatat tagaacttgt gtttttgttt
     9961 aggtctagag ataaagagag acaatttcca aatatatgta atgaatacaa aaagacgttt
    10021 gtcgcggatt accgttacaa acgtctttta ttgattttcc gagatctcat cagtcgccat
    10081 ttggaatggt tcactcctta tctagattcg tttaatgctc ggactgcttg ttcgattgta
    10141 ataccaaacg caacgttatt ttcgttttgt gcatcaatcg ccataaaacg gttagaagtt
    10201 gtatcaaaag ctacgcggta ttgcatattt gtttttgtaa acgtcataaa attcatctcc
    10261 tttgtaatgt aatttagttc ttgaaagttt cctttaaact ttcgaactta taccaagttt
    10321 agcatcgtac gttttttgat gcaattaaaa agcatttatc attttcctta tttatttttt
    10381 cttaaatggt ttagctattt tcttttaatc cgataagtag cccaatcatc aaggttacaa
    10441 atactattgc ttgaatataa atcatatgct cacctcttta taaataactt agcaatataa
    10501 agaaaaaaac gcacgaacaa cataggaata taaacaaacg tttttgtcac aacgtctaag
    10561 atcgtgttaa aaaatagtta tctaaaaagc agaaagatac tcaaaataaa aaataaaaaa
    10621 atgaataaaa acgttttcaa atacaaggta atttgttatt ataaaataaa gaaaaaacaa
    10681 aataaaaata aagaaaagag ggaatgaaat ggtaaaagca gaagtaggaa gatcttatat
    10741 atgcaaaccg atcggagtat ctcatgaact aatcggctgt attgaacgta catatatcaa
    10801 cacggctgtc gtgtatgttg aaagttatga ccaacgagac tatcaactta tcaatgaaag
    10861 caagtatcgc atgctcgtaa aattctgtga tattagcgca cctactgaat tggtttctta
    10921 aacagtattt ttgagaattc gcaagaactc ccttataata taaataaaga cagaagggag
    10981 cgagaagata tgccaaaaag aaaaagttca gggaaaatgg gaattattct tgcagtgatc
    11041 tctgcaattc ctgctatttt agctattgtt cgtgcgatga aggaatcaag agaaagttaa
    11101 gcacacatta tgagcgtcaa acaaaaaacg catatacctg cggtggcagg ttatgcgttt
    11161 tttgttgtat aaagactttt ttcattaacg atttttgatt agccgactcc caaaacaaaa
    11221 tttagcagtt tatctgaata agtgatttct tcatctgttt gtttcacact ttcatttagt
    11281 agtcccatct catcggttat gataccatcc acaccataaa acatcatgcg actcatggca
    11341 tctgaatcgt tgattgtcca tacatatact tcttttccgt cttggtgggc agaattaatg
    11401 aagttacggt tgatcgtact atattccatt gtcagaaaat cagcaggcgt cacagggggc
    11461 ccaacaatat tgaaaggtaa gatgtagccc acataaaagt ttggttctgc ttcttttaaa
    11521 tctgaaacgg tttggtacgt caaactttgc aaaatatgat ggttctctaa gataactttg
    11581 cggtatttat ggacaaatcg ttcgacaagg tcatccgaat cttttttaga ggtcttgatc
    11641 tcaataagta atttttggtt tagcttatgt gctttttcca aataagaatc aaaagaacaa
    11701 acaggggctt gcactccgtt ttcagtaact gtaagatttg tcaattcttt caatgtaaga
    11761 tcctgtggtg ttccatttac ccctgttaag tgacgaagat ttgcatcatg catcactacg
    11821 aaatgaccat cttttgtttc ctgaacatcc atctctacat aatcaggatg atagtctctg
    11881 cttgtttttt caagtgcttc taaagtattt tgcgccccat tttgggtact cacacctctg
    11941 tgagagacag tcactggttt tgtctgaaca gctgaagtca gataatccat attgtaaaga
    12001 cagacgccaa taccgaaaaa aactgcaaaa agagtcaaac cagtgttttt cagcgcagag
    12061 aaacgcaagt tgggggcttg tgggataaac cacttaggga tctcaggcaa gaagccttcg
    12121 tcatccatga aatcaacaat gatataaaaa atccctacgg tagacatcac gatattgaat
    12181 aataaaatcc cttgtaaaag cgtcatagca aacacagcgc tgatcaatgc atagtctggg
    12241 aaaaattgtt caaccatact ttgtgccaaa ataacaacga tatatcctaa agaagaaagg
    12301 agtaaaatcg taccgccaat cacaataaat tggcccgtga tggccaaaag acgcgatttg
    12361 gtcaatgacc agctttcccg aatggctgct cgaaaagaac gatctcgtag aatcatttcc
    12421 ggtaaagcaa aaatcagtcg aatcccaata tagccaagga aaatataaac gagtaaaaag
    12481 gaactgacga tgatccaacg attagcaaaa ataaaatcca taatgaaagc ggggattttt
    12541 atttttgaca gtagatcaga attaaaactt aatccgctga tcggtagaat caataaaaaa
    12601 taagcaagga aaaacaaaaa agtaatgggt ctcactttct tcagctgaag tatcgtcaag
    12661 tgtaagagtt gcttcaaaga gattggttct ttctttttaa taaaaaaaac actcatcaaa
    12721 agaaaagtaa attcgaaata aactaacagt aaaatcgtca tcaaaactac gattaacgag
    12781 agtagaaccc caggatgttg agaaaaaatt gaaggaatat tgtcataaga caaatagtca
    12841 attgcccctc ggtgtaaaat aaaacgggtc gtactgctca ataagggtaa acaaataaat
    12901 aaaataaagc catgcatcag caagacatca cggaaataag cttgtgttcc ttttaaaaag
    12961 tcccaagcat tacctaagct acgtttcaaa taattcatcc tatcacctgc tcttcacatt
    13021 gtagcgcaaa tctaatgaaa aaggaaaggg tgcagtgtgt tttgcagacc ctttcccaga
    13081 tttaa
//
LOCUS       DACGMI010000080        12981 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.083, whole genome shotgun sequence.
ACCESSION   DACGMI010000080 DACGMI010000000
VERSION     DACGMI010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.083"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(64..1173)
                     /gene="rpoD"
                     /locus_tag="IXT46_002564"
     CDS             complement(64..1173)
                     /gene="rpoD"
                     /locus_tag="IXT46_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAQ4948454.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(1197..3038)
                     /locus_tag="IXT46_002565"
     CDS             complement(1197..3038)
                     /locus_tag="IXT46_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAQ4948455.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(3220..5613)
                     /locus_tag="IXT46_002566"
     CDS             complement(3220..5613)
                     /locus_tag="IXT46_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4948456.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(5720..6580)
                     /locus_tag="IXT46_002567"
     CDS             complement(5720..6580)
                     /locus_tag="IXT46_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAQ4948457.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(6639..7271)
                     /locus_tag="IXT46_002568"
     CDS             complement(6639..7271)
                     /locus_tag="IXT46_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAQ4948458.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTNLMQSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            7480..8199
                     /locus_tag="IXT46_002569"
     CDS             7480..8199
                     /locus_tag="IXT46_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4948459.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            8225..10816
                     /gene="mprF"
                     /locus_tag="IXT46_002570"
     CDS             8225..10816
                     /gene="mprF"
                     /locus_tag="IXT46_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAQ4948460.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(11004..12191)
                     /gene="tuf"
                     /locus_tag="IXT46_002571"
     CDS             complement(11004..12191)
                     /gene="tuf"
                     /locus_tag="IXT46_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAQ4948461.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            12559..12915
                     /locus_tag="IXT46_002572"
     CDS             12559..12915
                     /locus_tag="IXT46_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4948462.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT         3727 a         2714 c         2309 g         4231 t
ORIGIN      
        1 tttttttctt ttaaaataaa ccaaacagtt ttactgattt ctcttctggt caatagtcca
       61 cgcttattct aagaaatctt ttaattgttt tgaacgagaa ggatggcgca attttcttaa
      121 tgctttagcc tcgatctgac gaatacgttc ccgagtaaca ccaaatactt tccctacttc
      181 ttccaatgtt ctcgtccggc catcatctaa accaaaacgt aagcgaagga cattctcttc
      241 ccgatcagtc aatgtatcta gtacatcttc caattgttct tttagtaact cataagctgc
      301 gtgttctgct ggacttgttg cttcctggtc ttctatgaaa tcacctaagt gagagtcatc
      361 ttcttcaccg attggcgttt caagggaaac aggttcttgc gcgattttca agatttctcg
      421 gactttttct gttggaagat ccatttccgc accgatttct tctggcgtag gttctcttcc
      481 aaggtcttgc agcaattgac gttggatacg tatcaattta ttaattgttt caaccatatg
      541 aactggaata cggatcgtac gtgcttggtc agcgattgct cgagtgatgg cttgacgaat
      601 ccaccatgta gcataggttg aaaacttaaa tcctttgcgg tagtcaaatt tttcaactgc
      661 cttcatcagt cccatgtttc cttcttggat caagtcaagg aactgcatgc ctcgtcctac
      721 ataacgttta gcgatactta ctactaaacg aaggtttgct tctgccagac gctgtttcgc
      781 ttcttggtcg ccttcttcga ttttcaatgc taacgctact tcttcttccg cagttaaaag
      841 ggagacacgg ccaatttctt tcagatacat acgaaccggg tcattgattt ttacaccggt
      901 tggcgcagaa agatcttctg tttttgcttg ttcagctttt ttctcagcac tcttcaagct
      961 gtgaattgat ggatcaccat tttcatccac cacactgata cctgcgtctt caatcttttg
     1021 gatcaatttg tccatttcat ctgcattcaa agtgaatggt gtagcaagct gattggataa
     1081 atcatcatat acaacttgtc gtttgggttt gttttctttg atgaaagctg ctactgctgc
     1141 ttcatacgtt tttttatctg ttccatttgc cataaaagaa ggcccccctt gagtagctat
     1201 ttggcttgtt ttaactgttt cgttaaattg atgatttcaa tcgtcaattc aagctcaagc
     1261 tgtttgtttc cagttcgtct ggcttcttgc tgcatttgtt tttttaatgt tatttcatca
     1321 gctaagccag atttgctgat cacatctagc aagtcttgga tttctcgtgg cgaactttct
     1381 tctgccaccg gtaaatattc gatttccacc accaaccgcc ttaaattttc atcttgcaaa
     1441 aagtctaaaa actctgcaag gttgaattca taatgttgtg agacatatgc atcgaataaa
     1501 aaataaactt ctgcatatgc atcatgaata aactgaaatt ctcgttcttt taaaatatta
     1561 cggacagaaa cttctttaaa tgcacgatat aatagaatct gctctgcctt ttctacttgc
     1621 gtcaaaggtc tctttttccg tgcagtttct tgtctcgtaa cctgagtgtg ttgactttcc
     1681 tgaggttctt gacgattttg ctgatttgtc cttcgaagat cgcgcagttg tttttgtatc
     1741 gtctctctgc cgatctgaaa ctctgttgac agttgagata gatacatatc ttgttcgatt
     1801 ggtgaaacaa ctcggctaag ttcaactagt aattcttcga ggtattcgat cttgtctttt
     1861 tcattatcta aatttttccc ttgttttaaa taacgtgatt taaaagtaaa gactgtttcg
     1921 cgcccatgag ccactaattc ttggaaagat gcttctccat acttacggag atattcatca
     1981 ggatcaagct tttctggaac gactacgaca gaaagtgcta atcgactgtt ttgccgaagc
     2041 aattcaatcc ctcgattggt tgcttcaaaa cctgcgttgt ctccgtcata gcaaaagacc
     2101 aattctttcg tcagcttttc catttgttgg atctgttgag ctgttagact tgtccccata
     2161 gaagctaatc cagttttgat accagcctgc catgcagcaa tcacatccat aaacccttcg
     2221 aacaacaaaa tttctccgtt tttccggata tcgcttcttg ctttatcaag attaaataaa
     2281 acttgtcttt tattgaacag ttctgtttct ggactattca agtatttggg ctgatctttt
     2341 tcctgccctt tttcaggtgc aagccagcgt cctgaaaaac cgatcgtctg gccttgagaa
     2401 ttacgaagtg gaaacatcac tctttgataa aaacgatcag acatacggcc atcatcatgc
     2461 gtgacaaaca atccagagcg ttctaacaat tcatttgaaa ttgattcatt cttgaatact
     2521 tgctgaagaa aagaacgctc attaggtgca aaacctatgt tgaattcttc aattaattct
     2581 aaagacaacc cacgactttg caaatattct aaagctggct gtccagcttt tgtatgcaat
     2641 agcatgtgat gatagatttc cgctgctttt tcatgagcag caatcagttt ccccgtagca
     2701 gattcaggat tttggacagc tatagtacgc tgacgccatt gatcttctaa cggtatctgt
     2761 tcgaagtctg ccacttttac cactgcttct ggaaaactta gaccttctag ttcttgaaga
     2821 aaagtaaaca cgtttccgcc tttaccacaa ccaaagcaat gaaaaatctg cttgtcttct
     2881 gcaacagaaa aagacggtgt acgttcttca tgaaaaggac acagccccaa gtaattttta
     2941 ccagactttt tcaactggac atattgtcca atcacctcaa cgatattcgt ttgactgcgt
     3001 actgtttcga taacctcttg aggaatccgt tgagccattt tttcaccccc tgctctattg
     3061 atatcttttg ggtttaacag aagatatttc aggagaataa ccggtaaaaa atcgcactaa
     3121 ctgaaatcag tgcgatttta aaggacacaa ttatacatgt ttgattgtat catatttcat
     3181 tgctttttca agtataacac atttctatct cattaagcat caatttgcta ctcttttcag
     3241 taactgattt tgaatatcag ccttccagta caatactcga agaacaatat ttacgagcat
     3301 gaatacaaag aagtatccta cgctctctcc caaccctaag tttacttcca aaattccatg
     3361 gaacagcatt gcagctacat atatccctac gatcgtcgtt actgctagga agatgcgcaa
     3421 tgggttgaag ggataacaag cttttacaac tgccatgcaa ctgatcccaa tcagcaagta
     3481 atacatcaaa gtagtagttt cagcatttcc ccatgcgaat gtttttccaa gtagatacac
     3541 cgcaatgata ttcactacta caagcaaggc atttggtaaa gcattaataa gtgctgtagg
     3601 caaataacgg taagtgattt ttcttttatc ttgttcaaaa gataaaaaga aggaaggata
     3661 cccttcaatc gctaaatcaa tcagcgtgat ttggataggg ataaacggaa atccaattgc
     3721 tgtaacggca catataatcg ataaaataaa tgaataaatc gttttgataa aaaagatgcc
     3781 tgagactttc gtcacattgt tgaccactcg gcgtccttca aacaggactt ctggcaatgt
     3841 agtaaaatca gagtccaaca ataccagatt cgcaatctga cgtgttgctc catcaccttc
     3901 tgccatagca atgctgcaat ctgcttctct taacgccaaa acatcattca caccgtcgcc
     3961 tgtcattgca accgttctgc cgctttcttt caattcattt accagcaatt tcttttgctg
     4021 cggactcact cgtccaaaaa ccgtatagcg atgagcagct tctcgcactt ccatttcttc
     4081 agtaatttga gaaagatcga catacgcatc ataattcggt aatcctgcac gtctagcgat
     4141 attggagaca gtaaaaggat tgtctccaga aatcactttc agatccacac cttcctcatg
     4201 aagataagct agtgtttctt gagcgttttt tcggattgga tcatcgattt caaacagagc
     4261 aaccggctca acaaatgctg gtttttcttc gttcaattgc tgatttggag cgatccccaa
     4321 cataagtacg cgatagccat tcgcttgggc tgtttttaga ctgtccggaa gccgatcttc
     4381 ttccaccaaa cgttcaggcg ctcctacgta cacgactccc agttctggaa attccatcgc
     4441 gccccatttg cgatcagaag aaaatgcgac tttgtttgtc acatcatacc gattagaaag
     4501 ctcaaaataa tctctcatag cccgcatagt gatgttgtta tcactgcttt ctgccagata
     4561 cgtccccata atttctggga tggctttctc gtacagcgga tgtagtgctt ctacccgctg
     4621 gatactcatt ttcccttcag taatggtccc tgttttatcc aagcataatg tatcgacatg
     4681 ggccagcgtt tcaattgaat acatgtcttg aacaaggatt cgtttttttg ccagtttggt
     4741 tacccctgtc gttaatgcaa tacttattag caataccaaa ccctttggaa gcatgcctaa
     4801 caaagctgct gcagatgcaa taacagaaat tttgatagaa gcatcgcgga tgaacagtgc
     4861 ttccaaaaat agtatgatcc ccaaaggaat aatcacgaaa ctagtgaatt tggatacttt
     4921 gcgaatcgaa tctacaagtt cagaacgaat agctttgtga gtctttgcct cgctagtcaa
     4981 gcggacagca taattatctg cacctactcg gataacttca gccatgacag aaccgcttgt
     5041 caaaaagctt ccagaaagca attcagctcc agtttctttg acaatcaaat cagattcgcc
     5101 tgtcaaaaga gcttcatttg cttctgcccg tccagatata acctgtaaat cggctggtat
     5161 ctgttctcct gctccgattt ttaccaaatc tcctaatacc agctctttag tagaaatcga
     5221 ttgttcttta ccgtcccgga tcactagtac ttctgattgg gaaacaatcg ataatttccg
     5281 tacaagattt cttgcatgta tttcttgata aattccaata acgatattga cgacaataat
     5341 tgctaaatac gccatgttgg aatacgcacc tacaaataac agacaaatcc caataccaaa
     5401 gttcagaaaa ttgaataacg tcaatatatt atcgctgaat atttgttttg tactttttga
     5461 tgcatcttcc tggtagtcat tttgctggcc agaagccatt ttctgaacta cctcttgctg
     5521 tgtaagtcca ttcattttct ttttctccat tttccgccaa ctttcaaaaa taatcacgtg
     5581 tttaagtcta gcgtgttcca agattaaaaa caacttgttt ttataaaatt tatagaaaaa
     5641 cacacgaatg attttacaaa aaagatgcca acctttttgt ttgaatcacc cgtgtgctgt
     5701 ttttattatc aatctatctt tacttatatt gttcctccaa acggctcatc caccaaccta
     5761 gtgctgtacc ggctataaaa agaacaggac aagctagtac cccagcaact cccaatcccg
     5821 cgtaatcggt aggaatgatc ataatcgttg aagcaaaaac tacacctaaa atgaaatgga
     5881 atagcttgct atatgccttt gagaaaatgt aatccatgat ttttgacaat ccaagaacac
     5941 aaagaatccc accaattccg atcggcacaa tcacttcaag tcgtacttct ttaaatccgt
     6001 cagccatcgc tttatacaat cccatataca ccaaaaaatt agaagggctc aatcctggga
     6061 cgatcatacc caaaccaatc aatccgccgg caatcagcca tgttccaaaa ttctgatcga
     6121 cttgcccgtc aaataattga gcgccgtata ataaaaacaa ataagccaga acaaaagtaa
     6181 caaccatgat gatcacatca gaagtatctc ttcctttttt ccctgcttct ttccataacg
     6241 caggaacagt tccagcgata catccgacaa aaaaccataa tatcgttgtt tcatacgcac
     6301 ctaataaaaa actgactaaa aaagaaagta gaaagatgcc tgtcactccg cctagaccaa
     6361 caggcagaaa aaacaaaaca ttttctttga aattttttgt aaggtgggct aaaaaagaaa
     6421 tcagccgctc atacatgcca aagacagctg ctaatgcacc accgctgact cctggcaaga
     6481 taaatcctga accgataaac attcccttca caaaccgtaa catccagtct ttggttgtgt
     6541 accccacttc ttgattttcc attttttgcc ttttttccac tatttgcgca ctccttcttt
     6601 catttaattt tattcatgat tgaacatttc ctgctatttt acttaaagac tttttcatag
     6661 gtctctatta ttttttcatt cattttgaca atatcaggat aaaacatgtt acctccatta
     6721 tgatagagat agccgccatt gtaaagcaag gactggatcc gccaatatcg gtattgtttc
     6781 ccttcctcat ttcctaaaag tgggctcagc acatctttag aatacgcttc tgctaattct
     6841 actgtgtttt ctccgccatg attttttaca taggcaatat aatctttccc aaaattatat
     6901 gcttggacag ctgtccataa atcgcatcct tgtttctttg cttctactat catttccgcc
     6961 aaatatttga caccttgatc aatactgtca gctggattat caatgatctc agcttctcca
     7021 tgcagacttt ccgagctctg catgagattt gtcccttttc cttttgattc ggtcaatatt
     7081 atcgccttga tcaaattctc gtagttttcc atatgataat tttttgcagc tgttgttatt
     7141 tctatttgat agctttccac tcgttttacc gaacgataag ttcttcctcc taaaaacaac
     7201 accgcaccaa taaccgtcag aatgatcatg taaaaaagaa tacggataat agataatcgt
     7261 tttcgcttca tttcatcacc tagttatttt gacatctttt tttatcttac tatttcttta
     7321 tcttcttggc tatttcttcc ttgatttctg tgtacgcctt aagaaaaaat gaattttcct
     7381 gtattttttg acatcttacg aaaatgatcg ttgtttttca gtaaaaacaa ttgcccaatg
     7441 actgatataa tcgttatact ttacacagta ggtgattatg tgaaaaaaga aaagaaatat
     7501 gcaaaaatgc cagatgggag cgaaatttac tatgaaaaga gcggtcaagg cttccctctc
     7561 tttttactgc atggcaatga cggcagcggc cgcttttttt cagaacaggt ccctgtactc
     7621 gaacgctact ataccgtgta tctagtagat agccgaggac atggtcgttc gacaaacgaa
     7681 gcatctatgt tgaattttca gttaatggcc gaggatctga atacgatcat gttgctggaa
     7741 aaaatcgatc aggcagattt tcttggattt agtgatggag caaatctagc actggtattt
     7801 gccagcagct tccctaaaaa agttcatcga ttgattttaa attctggaaa cacgcttgtt
     7861 aaaggcgttc gtttttctgc cagagtcatc agtaatattc attatgcatg ggtatggtta
     7921 ctctctttat ttcgcccaag tcttcgcaaa aatcttttag ttatcaaact tttgctgcat
     7981 gacatcgggc ttacagaaaa tgatttaaaa aaaatcaact cccccacttt gatcatcgtg
     8041 ggaaaaaaag atgtaatcaa gctaaaacat tctttgtata tagctaaaac tataccaaaa
     8101 gcttcctttg tgcttgtgaa agaacaagga catgaattag ctagaaaaga tcctgaacgc
     8161 ttcaatcgag aagttcttca atttctttct gaaacataac tattaggaat agaaggtgat
     8221 ttatttgtta aaaaatacca tacaatggct gaaaaaccac ctaggactgt tcaaaacaat
     8281 ctttttgatt tctgtcattg tcattattgt cggtgaattg atgtccatcg gtaaaactct
     8341 atctatccag caattaggag aaacgtttgc cactatacct gtatggaaaa gcggactaat
     8401 gctattgatt ggtcttatct ctgtgttacc tatggttggt tatgatatta ttttgaatcg
     8461 gatgcttgaa caaaagcaga atcctcgtta cctgtttgag acaagctggc tgatcaatac
     8521 gatcaacaat attgccggtt tcggcgggtt tgttagtgtg gggcttcgct ctgaactata
     8581 tggacaaaag aaagagagca gaaacgtgat ccaagcatta tcgaaagttt tcttgttttt
     8641 gatggctgga ctttctattt acagtctgct ttctttttta cttgtagtct tcacgccagt
     8701 tgctcctttt ttgaagcaat attggatatg gttgatcggc ggcggtctat attttcctgt
     8761 cgtcttttta tttactactt tcaaaaagaa aggattcctt ggtggtacct cacttaaaac
     8821 tcaaggacag ctattgctag tttcattgtt ggaatggacc ggtgtcctgt ttagtttcct
     8881 ttctgttggt tatttaatgg aaatccggat tgatctgtgg caaacaattc cattattcat
     8941 tgctgcttca gtgataggaa tcgtgtctat gattccagga gaaattggga gtttcgatgt
     9001 aatgatgatt atcgggttgt ccgctattgg tgtgccaaga gaaatagtcg ttgtgtggat
     9061 cttgctctat cgcctgttct actacatcat tccgtttttg attggaatcg tctttttctt
     9121 caaaaatatc ggttccactt ttgatcagcg ttattctggt atccctaaac aattagcaac
     9181 agaaattgcg cataaaatcg tggttgtctt attatacttt tctggaatca tgctagtact
     9241 ttctgccact atcccgcaag cttttacaga gtttcgctgg cttcatagtt tgaacccatt
     9301 gaaatttcat tttattatcc aatttcctag tatactattg ggatttcttt taatcattat
     9361 gggcagaggg atcgcagcac gtgtgaaacg agcatatttg cctacaatct tcttgattgt
     9421 tctagcttta ctttatgttt tattaagtga ttttagtttc acaccggtgg ttttcttgtc
     9481 tattctgctt ctgatcattc ttgcttctaa aaacgaatta tttcgggaac aattgatcta
     9541 ttcatgggag tggcgtacga tcgatggaat cattattggt gcactgtcct tgctttacat
     9601 cgttattggg gtatacaatc tgccagattt ccctcatcgg cgtcaccatt ttatttcctt
     9661 tttcttattt ccttctgaaa agatttggtt ttcgggattg ttggccatca tcgctgttag
     9721 tttcatgatc gttctatttg ttcatttcct tcaaggagaa aagaaacaga ttggcgaagc
     9781 ctttaatgaa gaaaaggccc tgaagatcct tacaacttat ggaggaaact ccgatagtca
     9841 attgatcttc ttaaaagata agcggatgtt tgcctatgaa aaagacggtg aaccaactgt
     9901 tcttctccaa ttcgcttgct tcaataataa atgtattgta atgggtgatc cttctggtaa
     9961 gaaagaagat tttccagaag caatcgaagc ttttatcgaa gaaacagatc gactatgcta
    10021 tttaccagtt ttctacgaaa caagcgaaga gattgttatg attttgcatg aattcggcta
    10081 cgatttcatt aagatggggg aagaagctta tgtagacctg aatagtttta caacttcagg
    10141 gaaaaaaatg aagggcactc gtgctgtctt gaatcggatc gaacgagaag gatttacatt
    10201 tgatgtctta caaccaccat tttctactga gcaaatgagt actttcaaaa atatctctga
    10261 taattggttg ggttcacgaa aggaaaaagg gttttcttta ggctttttct ctgaagatta
    10321 tctacaaaga gcgcctattg cagttgtcaa aaatacccaa gaagaaattg tcgcttttgc
    10381 aacgatcatg cctacttaca cgaacaataa agtaggaacg attgatctga tgcgatatga
    10441 ttctaaaaaa gcaccttctg gcagtatgga tttcttgttc ttgcatttgt ttgcctatat
    10501 gaaagaagaa catatccaat ggttcaattt agggatggcc cctctttcaa atgtcggaac
    10561 ttccagaaag agttttttac aggaaaggat tgcatacttg gtttacgagt ttggttctca
    10621 tttttattct ttccatggat taagagaata taaaagcaag tacgctacaa actgggtctc
    10681 acgttatact ctatattcta gagatagttg gattgcatat gttatgattg ctttgctgat
    10741 tattgataat gcgccagttg agcagacaca aggtagaata agtggtttga aaaaatggat
    10801 acgaagaaag tattaaaaac tgcataccga tagatgaaca ctctcatgat gaataaaaga
    10861 gactgaagta aaacgaaagt tcatgcttct acaatctctt cttatacaat tgaagaacaa
    10921 agagcggtcc aaacagaaat cctgtttgga ccgctctttt attttaaaca tttttcatta
    10981 ccaaaatatt cgagtcgcgt ttcttatgct tcgatctctg taacgatacc tgaacctact
    11041 gtccgtccgc cttcacgaat tgagaatgtc gttccgtttt caacagcgat tggatggatc
    11101 aagtcaacat caatcgtcac gttgtcacca ggcatgacca tttctgtatc ttctggcaat
    11161 gtgattgttc ctgtaacatc agttgtgcgg aagtagaact gtggacgata gttgttgaag
    11221 aatggagtat gacgtccacc ttcttctttt gtcaacacgt acacttctgc tttgaatttt
    11281 gtatgtggag taatggaacc tggtttagca agtacttgtc cacgttcgat atcgtcacgt
    11341 tggatccccc gtaacaacac gcctacgtta tccccagctt ccccgtaatc taacgtttta
    11401 cggaacattt ctacacctgt tacaactgct ttttgtgttt caggtttgat ccctacgatc
    11461 tctacctcat caccgacacg aacagcacca cgatcaatac gacctgaggc aacagttcct
    11521 cgacctgtaa ttgagaagac gtcttccact ggcaatagta atggtttatc tgtatcacgt
    11581 tctggtgttg ggatatattc atctactgta tccatcaatt ccataatagc agcttcagca
    11641 tctggatcgc cttgcaatgc ttttaatgcg gaacctttga tcacaggagt gtcatcgcct
    11701 gggaaaccat attcgctcaa taactcgcga acttccattt ctaccaaatc gatcaattct
    11761 tcatcatcga ctaaatcaac tttgttcaag aaaacaatca ggtattttac accaacttgg
    11821 cgtgacaata aaatgtgttc acgtgtttga ggcatcggac cgtcagttgc agaaacaact
    11881 aagattgcac catccatttg tgctgcccct gtaatcatgt ttttcacata gtccgcgtgt
    11941 cctggtgcat caatatgcgc gtagtggcgt ttttctgttt catattctac gtgtgcggta
    12001 ttgatcgtaa tcccacgttc acgttcttct ggagctgcat caatactagc atagtcttga
    12061 ggatttgcta ggcctttttt gcctaatact gtagtgatcg cagcagttaa agtagttttc
    12121 ccatggtcaa cgtgtccaat cgtaccaatg ttaacgtgtg gtttacttct gtcataatgt
    12181 tcttttgcca taatttacaa acctcctaaa taatatagat cactgaaaaa tttcagctct
    12241 caccttttta ttatagtctt tttttgacta aatcaaaaag aatacgtccg acttactttt
    12301 tgtaagattc gaactaagct tattatacgt caatattggt caaagtcaac taagagcact
    12361 cgtctgtctt atacgcgaaa aaagtacctt ttataaataa aaaaatgtgt tttttgagaa
    12421 aaacttcaag atagtcctta actttctttt gaagcaataa gaacaaaatg aggaaaagtt
    12481 taaaattcag ctgttgccaa caactttcaa tagacgaaat cttctatttc gttaataata
    12541 aggaaagagg tgaagtacat gaaaaaatta attggcgtac ttgtcgtttt aggcatattt
    12601 ctcggcggaa gttttgcagc ttatcattat ttttacggcg gcgaagctta ttatacaaaa
    12661 atcacgacga atggcgaaat gtcagctacc caagcagata acggagagaa attcacgact
    12721 tatacctaca agcaagcggc ttataataaa gatggtgaaa aaaaacaggt gacgcttcgc
    12781 gaagaaagag aacatccatt aaagatgaat gcgtatctta aactcaaagt caatcctcgt
    12841 aaaggtgtat taagctggga agaaataaag gcttctgaag tgcctaaaaa tgcggcagaa
    12901 aaaatcgata attagtaaat ggtcttaaaa ttttattaga taaaaagagg ctgggacaga
    12961 agcgtttaac tccaagaaat a
//
LOCUS       DACGMI010000081        12670 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.084, whole genome shotgun sequence.
ACCESSION   DACGMI010000081 DACGMI010000000
VERSION     DACGMI010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.084"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            6..305
                     /locus_tag="IXT46_002573"
     CDS             6..305
                     /locus_tag="IXT46_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4948463.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="IXT46_002574"
     CDS             378..1739
                     /locus_tag="IXT46_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAQ4948464.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="IXT46_002575"
     CDS             1761..2021
                     /locus_tag="IXT46_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948465.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="IXT46_002576"
     CDS             2035..2787
                     /locus_tag="IXT46_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAQ4948466.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="IXT46_002577"
     CDS             complement(2881..3486)
                     /locus_tag="IXT46_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4948467.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="IXT46_002578"
     CDS             complement(3539..4513)
                     /locus_tag="IXT46_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAQ4948468.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5670)
                     /locus_tag="IXT46_002579"
     CDS             complement(4891..5670)
                     /locus_tag="IXT46_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4948469.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPLDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IXT46_002580"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IXT46_002580"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAQ4948470.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="IXT46_002581"
     CDS             7161..8558
                     /locus_tag="IXT46_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4948471.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDFFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="IXT46_002582"
     CDS             8639..9079
                     /locus_tag="IXT46_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4948472.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="IXT46_002583"
     CDS             9227..9553
                     /locus_tag="IXT46_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4948473.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="IXT46_002584"
     CDS             9554..10303
                     /locus_tag="IXT46_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948474.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="IXT46_002585"
     CDS             complement(10383..10838)
                     /locus_tag="IXT46_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAQ4948475.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="IXT46_002586"
     CDS             complement(11265..11540)
                     /locus_tag="IXT46_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948476.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="IXT46_002587"
                     /pseudo
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="IXT46_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
BASE COUNT         4057 a         2174 c         2588 g         3851 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaaaatta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag atttttttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcgggtttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattag ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag
//
LOCUS       DACGMI010000082        12579 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.085, whole genome shotgun sequence.
ACCESSION   DACGMI010000082 DACGMI010000000
VERSION     DACGMI010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.085"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            6..2378
                     /locus_tag="IXT46_002588"
     CDS             6..2378
                     /locus_tag="IXT46_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948477.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNDQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERIENKVQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     TPTDSVKEKETDHFYRVEFNENDPAKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELARLCEQVPEKEQKQTVKNEPISKV
                     QNEIKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DQTGHTELQVGIQAVAKNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     ATWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQD
                     EKNVVETAEQKNIVLVGSLWIDKKDGKVLEEDTGRTLHLKDAAFIEDTQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2439..3899
                     /locus_tag="IXT46_002589"
     CDS             2439..3899
                     /locus_tag="IXT46_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAQ4948478.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPDWLIDYAEKEGLIAELKPKHERQNF
                     LVQDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEMKVEPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKGCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIHQQEIRKQKRAMLFQQGKQQERE"
     gene            3910..4353
                     /locus_tag="IXT46_002590"
     CDS             3910..4353
                     /locus_tag="IXT46_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
                     /protein_id="HAQ4948479.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQ"
     gene            4438..6114
                     /locus_tag="IXT46_002591"
     CDS             4438..6114
                     /locus_tag="IXT46_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HAQ4948480.1"
                     /translation="MNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRNFQ
                     KEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVETE
                     KKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAIQGLYEGKYLSYPRTDTPYITEGEY
                     AYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQLS
                     PLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPLDLGWKKLFGKES
                     DGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSEEA
                     QSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLTSA
                     EMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKAAS
                     EKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEIIQN
                     SRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTAK"
     gene            6360..6956
                     /locus_tag="IXT46_002592"
     CDS             6360..6956
                     /locus_tag="IXT46_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4948481.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDTERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            6969..7868
                     /locus_tag="IXT46_002593"
     CDS             6969..7868
                     /locus_tag="IXT46_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAQ4948482.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKEQKLAYQRHQQMNREMER"
     gene            7871..8355
                     /gene="ssb"
                     /locus_tag="IXT46_002594"
                     /pseudo
     CDS             7871..8355
                     /gene="ssb"
                     /locus_tag="IXT46_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            8377..8634
                     /locus_tag="IXT46_002595"
     CDS             8377..8634
                     /locus_tag="IXT46_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948483.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(8793..8927)
                     /locus_tag="IXT46_002596"
     CDS             complement(8793..8927)
                     /locus_tag="IXT46_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HAQ4948484.1"
                     /translation="MLKSIKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK
                     "
     gene            9070..9330
                     /locus_tag="IXT46_002597"
     CDS             9070..9330
                     /locus_tag="IXT46_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948485.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            9779..9985
                     /locus_tag="IXT46_002598"
     CDS             9779..9985
                     /locus_tag="IXT46_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAQ4948486.1"
                     /translation="MRKKFDYLGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIEEKGKKR"
     gene            9985..10236
                     /locus_tag="IXT46_002599"
     CDS             9985..10236
                     /locus_tag="IXT46_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948487.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGCELHYQENLETYENEYWLTKLEN"
     gene            10252..10689
                     /locus_tag="IXT46_002600"
     CDS             10252..10689
                     /locus_tag="IXT46_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948488.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCFEIGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            11125..11313
                     /locus_tag="IXT46_002601"
     CDS             11125..11313
                     /locus_tag="IXT46_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948489.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IACIGQYLYCIRGRKLYA"
     gene            11371..11637
                     /locus_tag="IXT46_002602"
     CDS             11371..11637
                     /locus_tag="IXT46_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948490.1"
                     /translation="MGTGFIDRVLVQVKEERKITMKYNLLDHKRMWVEKLEEDLEQLE
                     LLGHNKTSTVYKEGLKRTKKAQKELATLESRVQKKEVDLTHTYL"
     gene            11647..11880
                     /locus_tag="IXT46_002603"
     CDS             11647..11880
                     /locus_tag="IXT46_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HAQ4948491.1"
                     /translation="MADKRKEKIQKLLALAADVNDEESVSALAKAQQLMMDYDLTEDE
                     IFNYHEQQRIEAVETHVIYRGRPQKWLYRLFRN"
     gene            12223..12405
                     /locus_tag="IXT46_002604"
     CDS             12223..12405
                     /locus_tag="IXT46_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAQ4948492.1"
                     /translation="MSVSTLGITVDAATYYGNGVYCNTQKCWVDWSRARSEIVDRGVK
                     AYVNGFTKVLGGVGGR"
     gene            12395..>12579
                     /locus_tag="IXT46_002605"
     CDS             12395..>12579
                     /locus_tag="IXT46_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948493.1"
                     /translation="MEDKKEKLFDLIANAYNSKSYNNVEVKEGFLQDAKKIREDKPYP
                     EIIISVYKHLSKLKAEER"
BASE COUNT         4656 a         2076 c         2646 g         3201 t
ORIGIN      
        1 cggacatggc agaagaaaaa gaaccactag acaatagtcg tttgggaaaa tccaaaagaa
       61 aattagtacg attgcaaaat gaattaaatg atcaaatcga aaagatgttt gaacaccaaa
      121 gaaagaccaa cggtcaacca atgaacgata agagaaacgg gcattcttgg tttaggcaac
      181 aagaacgaat cgaaaataaa gtccaaagtc tgagagaaga gatcaagcaa caagaaaaac
      241 aggtagaaaa acttgaaaga caagaagagc taaaggaaat gggttataac aagtacggtg
      301 gcctggatat gacgatcgaa aatattccaa gaatcaaaga agaaatcgaa cgctttgaaa
      361 aaggtgaatc gactttttca gctgccacga tccgaaaata ccaacgaaaa ttggaaacat
      421 tagaacagct gaaagaaaaa tcagagaaag gaaaagaaaa tattcttcct gaagtacaag
      481 cgatcattga cagcggacga gtgacgcaat ggaaaaagaa tccaactatc tattttctga
      541 aaggctatcg aaaagtcgct ttagaactca atgaaaacgg gggatttgag gaatctaaaa
      601 aataccaagc cacgtcggaa gaagaaaagg cagctgttcg tgaattactt gaagaagcta
      661 cacctactga ttctgtgaag gagaaagaaa ccgatcattt ctatcgagta gaattcaacg
      721 aaaatgatcc agcaaaaggg ttgaaaagtt atggtgggga gatcgtaaca ctagaattga
      781 tcgatcaact caaaacactg gataaccaat acgccgcaga agcaggctat tataaattct
      841 attttgaaga agtgaagaat ggagaagtag tagatcagat acgaatggat ctaggggatg
      901 gcgtcaatag taatcacccc atctatttag agttagctag attgtgcgaa caagtacctg
      961 agaaggaaca aaaacaaaca gtcaaaaatg aacctatttc aaaagtacaa aatgagatta
     1021 aagagacaaa aacaaaacaa aagggttatc aaaaacgaac ggcagaagag attaagcaag
     1081 aagtcaaatc actttcccaa caggcgcttg atgcggtgaa aaagcatact cattcacctg
     1141 aagacgtcaa agaacttttg aattttatgt ctcgttttcc agaacgatcc tttagaaatc
     1201 aattattgat cgaggaacaa tttccaggcg caacggcttg tttaggtcgt gccgcgttga
     1261 aaaaagaagg aatctatatc aaaaaagggg aacaagggaa caagatcttt gtcagaaaaa
     1321 cggtcaaagg attttatgag aaaggacgtg gctttgttcg agaaacagag gctacaccag
     1381 aagataaaaa acgaatcgaa agtggtcaaa tcgaagtgat caaaaaacct tactacacga
     1441 ttgaaaaagt gtttgatatc acacaaacac aattgaagcc tgaagactat ccgaaaatct
     1501 tcccgaaccg cgtctttgat tttcaattgg atcaaacagg gcatacagaa cttcaagttg
     1561 ggattcaagc ggtagccaaa aatattggaa ttcaaattcg agatatgaca gaaagtgaag
     1621 tctatcaaag agaattagga caagcacgtg gggcgtacgt tcgtaacgaa tttactggcg
     1681 aagaagaaat cgtcatgaat actcgaaata ctcctacgca gcatttagcc acaagtattc
     1741 acgaattagc ccatgctaga atgcacaaat tttcagaatt agatactgca acaaaagaac
     1801 tacaggcaga aatgacctcc tatattgtgt gcaagcattt tgggatggac acctcggaga
     1861 aagctattcc ttatattgcg acatggacga agaatggtca gacgttggat gataaggaag
     1921 ctgcggaacg tgggaaaatc atgaatgatg tcagtcgtgt cgcaaatgaa ttcattcaaa
     1981 ccatttctaa tgaaatcaat caatacagag aaagagaacc agagatccag ccagcagaag
     2041 tgaagcagga tgagaaaaat gttgtagaaa cagcagaaca aaagaatatt gtgctcgttg
     2101 gctcactttg gatcgacaag aaagacggga aagtcctgga agaagacacg ggccgaacgt
     2161 tacatttgaa ggatgcggcg tttattgaag atacgcagca taatcaagtg attttaaaag
     2221 gaaaaagtta tggaaaagag attcaaacgg cgttaccttc agaagaattt gcgctaggaa
     2281 atccattccg attttcactt gaaacagtgt cagaagtggc caaacgaaaa aatgaaatct
     2341 attatgaaca acaattgtca caaaaagaac gcgtataaaa caagtaaaaa agactatctg
     2401 aaaaacggat agtctttttt cttttgggag gtttgaaaat gaccgagaaa aaaatgagtc
     2461 ttattgatcg atgtaaacag atcgatatag tggattttgc tcgaaacaat ggaatggctg
     2521 tagtcaataa aggacgagac tatcgcttag aagaccatga ttcatttgtt tttgatcgaa
     2581 gaaaacaacg tttttattgg aacagtcaaa atattagtgg cgacattatt gaattagcta
     2641 aacttttttt catagacaaa gagattcaag actctaagca acaatttaaa gcagccacag
     2701 attttattct aaagaatgaa gacaaaacag aacgagtaga aaatcttcat tttgagacag
     2761 aaaagtacaa agatcacccc gttgattatc aaccactcac agaaaaagga aggaattatt
     2821 tgaaggaaga acgaaaactg cccgattggt tgattgatta tgcagaaaaa gaaggattga
     2881 tcgccgaact aaagccaaaa catgaacggc aaaatttctt agttcaagac gatcgtttgg
     2941 atcatgcggt cgccttttta tggaaagatc cacagacaaa agagacagta ggggcgagtt
     3001 atcaaggaac attcattgat tatgaacgtt ttggtgagag aggcacatat aagcatatag
     3061 ataaaaattc gacagcgaat catggattta acctaaagat cggtgaccct aaacagttaa
     3121 aattttttga gagtagtatt gatttactta gctatgctgc actgaatcgt gatcagttaa
     3181 acgatacgtg gttagtctct atggaagggt taaaacacca tgtgatcagt cattattttg
     3241 gtgaggcagt atctgaattg agaaagaaac aagcctttcc tcaatccatt gagatttgtg
     3301 tggataatga ccgtgcagga catattttct acgaaaaaga acaattaatg ggcgcagttg
     3361 atccatttac gaatcagaaa gtacgttgtg aacgaggaat cgctaatgat tggcaagtgc
     3421 caaaagaata caaagtcatt tatgaagaag ttgcaaaaga aatgaaagtt gaacctgaag
     3481 caattatggc catacacaag acagaaaaca atctgcaatt aacgaaccaa ctggtttccg
     3541 ctcacaaagt aaatgcgtct tttggtcagc agctttctgt taacgattca atagaagcta
     3601 ttaatttgaa agatatttgt agagaagtcg caaaagaatt aaaaggttgt gaacgcgtgg
     3661 atggtacgta cgattttgat cgtttttatc aagaaaaagg ggatattaat gctcagattc
     3721 ttttctctta taaagcagaa caatactaca aaggctataa aaatcatgaa catgaatttg
     3781 tacctgaagt aaaaaaggat tggaatgatc aattgaagca tgaaatccac caacaagaga
     3841 tcagaaagca aaaacgtgcg atgttgtttc aacaaggcaa acaacaagaa agggagtgaa
     3901 atcgtcatga tgaaaaccgt tattttagca gaaaagccgt cacaagcgaa agcttatgcc
     3961 gatagcttct ctaaagccac ccgaaaagac gggtattttg aaatccaaga tagattgttt
     4021 cctggtgaaa ctgtgatcac gtatggtttt ggtcatttag tcgagttaga ttcgcccgat
     4081 atgtacgatg aaaattggaa acaatggtca ttagagcatt tgcctatttt ccctacacat
     4141 tatcactatc atgttcctaa agataagaaa aagcaattca aggtggtgaa acagcaactt
     4201 caatcggccg acaccattat tattgcgaca gatagcgatc gtgaagggga actgatagct
     4261 tggacgatca ttcaacaagc aggcgccgat catggaaaga tatttaaaag actttggatc
     4321 aactccttag aaaaagaagc catttatcag tgattccagc aattacgaga cgcagaagag
     4381 acctatccca aatttgaaga agcacaagca cgccagatcg ctgattggtt gatcggcatg
     4441 aacggcagcc cactgtatag tttactcttg cagcaaaaag gcataccagg aagtttttcc
     4501 ttaggcagag tccaaacccc aacgctttac atgatttatc agctgcagga aaagattaga
     4561 aacttccaaa aagagcctta ttttgaagga aaagcccaag taatcgctca aaatggcgca
     4621 tttgatgcga agcttgatcc gaatgaaacc caagcgacgc aagaagcatt tgaagattat
     4681 ttaaaagaaa agggggttca attgggaaaa cagccaggta cgatccacca agttgaaacc
     4741 gagaaaaaaa gtgcggcaag tccacgtctt ttttctctat ccagccttca gtctaaaatg
     4801 aatcagctca tgaaagctag tgccaaagat actttggaag ccatacaagg gttgtatgaa
     4861 gggaaatatc taagctaccc acgaacagat accccttata ttacagaagg ggagtatgcg
     4921 tatctgttgg atcacttaga cgaatacaaa cactttttaa aggccgaagc cattcctact
     4981 cctattcata caccgaatag tcgatatgtg aataataaga aagtccagga acattacgcg
     5041 atcattccta caaaaacggt catgacggca gcggcttttg aacaattaag tccactgcag
     5101 caggccattt atgaacaagt gttaaaaaca acggtggcca tgtttgcgga aaaatatacc
     5161 tatgaagaaa caacgatctt gacgcaagtt cagcagcttc agttaaaggc aatcggaaag
     5221 gtgccgctag atctaggttg gaagaagtta tttggaaaag agagcgacgg aaaagagaag
     5281 gaagaagagc cgctacttcc taaagtgaca aaaggagaaa tggtgacggt ggatctacaa
     5341 gttcttgaaa aagaaaccaa gccaccacaa ccttataccg aaggtacgtt gatcactgca
     5401 atgaaaacag ctgggaaaac cgtggatagt gaagaagcgc aatccatatt gaaagaagtg
     5461 gaaggaatcg gtacagaagc gacacgggcg aatattattg aaaccttgaa acaaaaggaa
     5521 tatatcaagg tagagaaaaa taagctcgtg gtgacgaata aagggatttt gctttgccaa
     5581 gccgtggaaa aagagccgct gcttacgagc gccgaaatga ccgccaaatg ggaaagctac
     5641 ttgttaaaga tcggtgaacg aaaaggaaca caaaccactt ttctagccaa tatccaaaaa
     5701 tttgtctctc acttattgga agtcgtacca gggcaaatcc aatccactga ttttggatcg
     5761 acgttacaag aagtgaaagc agccagtgaa aagcaagaag ccgcgcgtca tttaggaatt
     5821 tgtccaaaat gccaggaaca agaagtcttg ctctatcaaa aggtggcagc ttgtacgtct
     5881 gaagcctgtg attttaaatt atggacaacg attgccaaaa agaaactcac agcgacacag
     5941 ctgaaggaga tcattcaaaa tagccgaaca agccaaccag tgaaagggtt aaaaggtcag
     6001 aagggttcat ttgaagcaac gattgtttta aaagaagact tcactacagg ctttgaattt
     6061 tctgaaaaga aaaaaacgaa cttcaagaaa agaacacgcc gcactgcaaa ataatggagg
     6121 gttaatctta tgcgtaatac cacacacaaa caacaagaaa tcgaaaatca aaaagccaaa
     6181 attcgttcag aacaggaaaa aatgcgtgcc agcaaacgaa gactgcagca attgaagaac
     6241 cagcagagga ttcaaaaaga aatcgaatta gatcgataaa atcttcctaa ctattgtata
     6301 cgtataaact tatgttatac tgtttttata agtttatacg tatacaaagg agggagaaaa
     6361 tgacaaaagc aatggtatac aagctgctag aagaatttaa tggaactttg gctttgaagg
     6421 atgccaaaaa agcgggcatt tctcctgtaa cgatcaaacg tatggtagat cgaggggagc
     6481 tggatcgaga gtatccaggt tttttcacct tacctggtca atttcctgat gaattgttta
     6541 tggcgcaaaa aaaatatgaa cgcggcatta tttcacatat taccgcgtta gatttgtatg
     6601 atttaacaga tatgatccct agacagatcg atctgactgt accttacggt tatcacgttt
     6661 ctgaaaaagg attgaaggaa ttcgcagttg agctacacta tacaaaagcg gaatggtatg
     6721 aattaggtaa gattgaaata aaaagtcgct atgggaatcc tattatagct tatgatacag
     6781 aaagaacttt atgtgacatt tggaatccct ggtataccgt tgaggatgaa atcaaagtaa
     6841 aagcaatcaa aaactatatg gagtcggaca gaaaaaatct tagaaaattg aatgagtatc
     6901 gacgaatttt accaacagac aaaacgatgc gttcttatat tatggcttta aattaaagga
     6961 gaagatacat gacacctacg cagttaaaag caaaagtgaa gaatatttct agagaaaaag
     7021 aagttgatcc gcagcttgtt ttaagacatt ttatgatgga aaaattcttg gaaaaaatct
     7081 cagagtctcc ttatcgtgaa aattttgtgt taaaaggcgg cttcttgatt ggctcaaagt
     7141 atggcattga aaatcgcaca accaaagata ttgatacgac tttacgggaa atgaaagtaa
     7201 ccaaagaaac attaacaacg gttctaaacg aaattttttc aacgccgacg aaagaaggca
     7261 ttcaatttga gattcaagga atgaaagaaa cgagagaagc cgattactat ccaggattta
     7321 gcttacgtgt gctggcacat ttggaaaaca tgcggccaga ttttaaggta gatgtgacta
     7381 caggtgactc gatctatcct gcaacgatca ctcacagtca taaattgatg tttgaggatc
     7441 gaacgattcc tttggaatcc tatcctacag aacaaattat tgctgaaaaa ttaagtgcaa
     7501 cctttgattt tttaacagat aattcgagag gaaaagattt ttatgatctc tatactattc
     7561 ctaaaatgga gaagatcgat gagaagacct tgaaagatag tgtgagaaat acatttacac
     7621 gtcgaggaaa aactgatccg ttaaagatat actatgaaaa ggatatggat gtactgaaaa
     7681 atagtcacga gctaaaagat acctggaaga aatatcaaaa aagcaatcct tatgctgcat
     7741 cgatcacgta cgatgagaca atggattcga ttagtaattt gatggaaaaa gtgattcacg
     7801 tcgaagaaaa agagcaaaaa ctagcttatc aaagacacca acagatgaat agagaaatgg
     7861 agagataaag atgattaata atgtgacatt agtaggacgc ttaaccaaag atcctgattt
     7921 acgttatacc gcaagtggta ctgcagtagc gacttttacc ctagccgtca accgaaattt
     7981 cacgaatcaa aacggcaatc gagaagccga ttttattaac tgcgtgattt ggcgcaaacc
     8041 agcagaaaca atggcgacat tagctaaaaa aggtagcttg attggtgtag ttgggcggat
     8101 tcaaacgcgg acttacgaca accagcaagg acaacgtgta tatgtgactg aagttgtagc
     8161 agataacttt caactattag aaaataaagc agcgacagag agccgtgcgc acgctgatca
     8221 atcgtccacc agtccaagca ccgccacctt tgaacaacgg atacagcgac gcctaacaac
     8281 aatggattga acgcttcaca gaatccattt ggtggacaat caatcgatat tagcgatgat
     8341 gatctaccgt tttagtttga gaaagaagga gtaagcatgg caaaaaaaat tagtctgacg
     8401 atggatctat tgatacccgt aattgcattt atagacggga tttctttggg cgtcactgaa
     8461 aatcctttgg taaatagaat tgcgaaagga tcactatttc ttgtattcgt gtatcttgtc
     8521 tgttcttatc ttttaaaaag agcaggaaag gataattcct tttggcgatt gactaaagtc
     8581 acagtagcag cgacagctgt tatacttacg gctattctac cgctttatat gtagagttaa
     8641 cgggaaatcg ttgaacttct tgcgaaatat tgctataatg aacatgaaaa agaggagttg
     8701 cgctaacaac ccctcattaa cagcaccgat taaagaacgg tggcagaata ttagttattt
     8761 ggaaataacc gctgacctgc taaagtagac ggttatttct ttttgtcatt tttaagcata
     8821 tttacaatca aactaatcaa agcaatggta aacataccaa aaccaagaat ggtttgaatt
     8881 gtctcatatg cggacaaaag gcttactcct tttatagatt ttagcactta cattcataag
     8941 caccaccacc tttccagaag tcgccaccgt cttcaaactt tactgtcttg actattatag
     9001 catatctaaa atcgaataaa aattctcaat tttaactgtt tttgctataa ttttagcgag
     9061 gtgatcgtga tgaacaaata tgttggtttg cttgataaaa tccgagtaat aaaaacacaa
     9121 ccattattgg ttcgctttac tttacaaaca attcatgaat cgattaattg tgtagttgca
     9181 gatattgaaa ttatcgataa attgttaatt atggatgatg gaaaatacaa tattgccgtc
     9241 acaggtcatt tcaataaacg gaatcaatta gtcattgaat cgatgcaaat tagaaaccct
     9301 gatcatttta cgcgatcaat gggcatataa ataaaagaag agctgcaatc ctaatgtagg
     9361 actgcagctc tttttgtttt acatagaaac aggaagaaag ggaaaggcct gtttaggaag
     9421 gcacaagtgc cttctcaatt gaaaaacctt tctctcactc caaccgccac cgccgttcga
     9481 gaagaaagga agtgaacgtt gcacgttcac taagataagg ggtcttgctt tgtaagacaa
     9541 aataggaaaa gcttcctctc accaaaaggt tcgttcctgt tcgctatctc tttattgatt
     9601 tgccagaccg gcaacaagtt gccttttatc accaaaaagc gacaaggaca agggtaaatg
     9661 gcacgctgcg cgcccttgtc cttgtcgctt ttcgttgatt cattctggcc aacaaatcaa
     9721 taaagaaaga actaacgaaa ggaagtaaaa cctttcctaa gaggaggcag aatcaatcat
     9781 gcgaaagaaa tttgattatt tgggtgttcc cttcagcgaa ttattcccaa actatcatgc
     9841 accacatact gtcgaatgcg attgtggaga aagagcgaaa tgtatcaaaa gctattgttt
     9901 gtatcaatgt ccaacatgcg ggaaaaaata taccttgtct tatggcgatt atattttgat
     9961 tgaggagaaa ggaaagaaac gctgatgaaa acacaacaca aattattgac tgtaaaagaa
    10021 gtcgttcaaa ttttggtgga caaagaagtc atttctgaaa aagtagcaga agctttactt
    10081 attccgcggt actggacgat agaaacccct ttagtagagg atgcaccgac tatgctattt
    10141 gaagacctag tgaagattgc aggatgtgaa ctgcattatc aagaaaactt ggaaacttat
    10201 gaaaacgaat attggttaac caaattagag aactaaaaag gagaaaaaaa tatggctcaa
    10261 aattactatg acgaatttgt caaattacct ttggataaaa tggcacaaaa aatggaggat
    10321 atgacgttcc tatacaacga aacacgtgtt ccaaaaaaac attataaaga aaaattgtcg
    10381 gtagctgtgg aagaaatgat tgaatcaggt gtcgaaatga atcttattgc gacgtactat
    10441 cgaacactgg aagaactgaa aaagcaaaat gcaaaatggt ttttccaagc cttactatgc
    10501 tttgaaatag gtgtcaaacc aagcactatt aaaccttctg aataccaggc tttagaacta
    10561 acgtatgcga aatttatcga aacgaaaaaa gccaagactg tttcaagtga atggttagat
    10621 tattttgaaa atatcaataa gtatggcgca tattacacca tgaaaaagga agacaacgaa
    10681 aatgaataag gtgatttatc aactaacaac ggattccata tcaacgattt gaaagaaaaa
    10741 aaggtcaata atcatttata ccgaaaagtg agaatgtgtg gaataaggaa aaaaaaagcc
    10801 tagtaactaa gggaatggtt cttatttcgc accaaccgcc cccgccgctt aggtggtgcg
    10861 aaataaacgg gcaaagcccg ataacttaag agaaagaagg tgatccattt gaaaaagatt
    10921 attcccttat tgttagtact gtttgttggc gaaatactta tgcgagatag tgcagctgta
    10981 cagttaaacc tcgctgtatt tttggtaata ctggtgtttt gtttgatctt ttggcggttt
    11041 gtattagtcc tcgtgagtct actattcaag atgattgcag ccatattttt catggggtta
    11101 tttcgatgaa aggagagagt accaatgcca attgcaatag gaaataaacg gttacccgtg
    11161 acattagatg aaaagagaca aaaagaattg cagcaactaa agcagaagta cggcaaaagt
    11221 gaatccagga ttatgtgtat tgcgttagat ttattgattg cctgtattgg acaatatctc
    11281 tattgtattc gaggaagaaa gctttacgct tgaatgcgat aagttaaccc gatatatcga
    11341 tccaaaattc tatgaggata aaaacctggc atgggaactg gctttataga cagagtgcta
    11401 gtgcaagtaa aggaagaaag gaagatcacc atgaaataca atttattaga ccataagcga
    11461 atgtgggtag agaaattaga ggaagactta gaacagttgg aattgttagg tcataataag
    11521 acttcaacgg tgtataaaga aggactaaaa cgaacgaaaa aagcacaaaa agaactagca
    11581 acactggaaa gtagggttca gaaaaaagaa gtagacttaa cacacactta cctttaggag
    11641 tagaaaatgg cagacaagag aaaagaaaag attcaaaaat tactggcgct tgcggcggat
    11701 gtaaatgatg aggaatcagt gagcgcatta gccaaagccc agcaattgat gatggactat
    11761 gatcttactg aagatgagat tttcaattat catgagcagc aacggataga agcagtagaa
    11821 acgcacgtga tctatcgtgg acgtccgcaa aaatggctgt atcgtttatt tagaaattaa
    11881 gataaaaaag gctagttaac aggtttgttg actggccttt tttgatatgt ttgtacatgt
    11941 tttattgtgt tttaattttt ctctttttta tagcaagctc cttttataat aaatattccg
    12001 aaaagtgaag accatttttt atttattaag actattatta ttagtgagat aaaatttgat
    12061 tgatcttaca gaatattggt gacgattatg acactaaaga tactatttat gaaaattttg
    12121 caaaaatgtt ctgaaaatta catataattg ttttataaaa aagggaggca attatatgaa
    12181 gaaaaaattt gttagtattt tttgatttta ggaattgttt tattgagtgt atctacttta
    12241 ggaattacag tagatgctgc aacttattat ggaaatggtg tttattgtaa tactcaaaaa
    12301 tgttgggtag attggagtag agctcgctct gagattgttg atagaggagt aaaagcttac
    12361 gttaatggtt ttacaaaagt gctaggtgga gtcggtggaa gataaaaaag aaaaactttt
    12421 tgacttaatt gcgaatgcat ataattcaaa gtcatataat aatgtagaag taaaagaagg
    12481 atttcttcaa gatgctaaga aaatacgaga ggataaacca tatcctgaaa ttattatatc
    12541 agtgtacaaa catttatcta aattaaaagc tgaggaacg
//
LOCUS       DACGMI010000083        11740 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.086, whole genome shotgun sequence.
ACCESSION   DACGMI010000083 DACGMI010000000
VERSION     DACGMI010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.086"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(222..2297)
                     /locus_tag="IXT46_002606"
     CDS             complement(222..2297)
                     /locus_tag="IXT46_002606"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAQ4948494.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRVSRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQITAMALSL
                     ASLDQIITK"
     gene            complement(2299..3216)
                     /gene="glyQ"
                     /locus_tag="IXT46_002607"
     CDS             complement(2299..3216)
                     /gene="glyQ"
                     /locus_tag="IXT46_002607"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAQ4948495.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(3600..4412)
                     /gene="recO"
                     /locus_tag="IXT46_002608"
     CDS             complement(3600..4412)
                     /gene="recO"
                     /locus_tag="IXT46_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAQ4948496.1"
                     /translation="MSQLVESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            complement(4555..5454)
                     /locus_tag="IXT46_002609"
     CDS             complement(4555..5454)
                     /locus_tag="IXT46_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAQ4948497.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5469..5870)
                     /locus_tag="IXT46_002610"
     CDS             complement(5469..5870)
                     /locus_tag="IXT46_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAQ4948498.1"
                     /translation="MPMDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5848..6324)
                     /gene="ybeY"
                     /locus_tag="IXT46_002611"
     CDS             complement(5848..6324)
                     /gene="ybeY"
                     /locus_tag="IXT46_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAQ4948499.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6341..8533)
                     /locus_tag="IXT46_002612"
     CDS             complement(6341..8533)
                     /locus_tag="IXT46_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAQ4948500.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEVQEE"
     gene            complement(8557..9528)
                     /locus_tag="IXT46_002613"
     CDS             complement(8557..9528)
                     /locus_tag="IXT46_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAQ4948501.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10234..11613
                     /gene="brnQ"
                     /locus_tag="IXT46_002614"
     CDS             10234..11613
                     /gene="brnQ"
                     /locus_tag="IXT46_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAQ4948502.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT         3199 a         2450 c         2147 g         3944 t
ORIGIN      
        1 tagggaaatt cctaatttaa aagtaaataa aacagtaaca agattattat taatcttttt
       61 catttttatt tcctcacttt tcatgagcgt tttgaaaatt ctagcaaaga ataaaataac
      121 aaaaattatt aaaatagaat taataacagc ttttatattt ataacaaaaa aacagagaca
      181 cagcacgttt cgtgcatgct ctctgttttt caaacaaaag actattttgt gatgatttga
      241 tccaagcttg ctaatgacaa agccatggca gttatttgac taagttgtgt tagtcggttc
      301 ttacgtactg ctggttcatc agccatgacc atcgtttgat caaaataatt ttcgatcagt
      361 ggacgaagag cgacaagctg gtcgtagttt tcgtggatcg tttggtcagc aaaacttgct
      421 ttcattgctt ctactgcttt gtgtaattct ttctctgcgt cgttttcgaa cagctcaggg
      481 tctacttctg attgtttttc aagctgcgct tttttcgcta agttcacgac acgtgtcaat
      541 gcttccattg aaggtttgaa gtcttcatct gcaagatgtt gtttgaacaa ttgtgctgct
      601 gcaaatactt ttgtcagatc tttttgttct gcattcaaaa cagcttcgat gacatcatga
      661 cggatattct tcgttgtcaa taattggcgc agacggcctt tgataaagtc gatcacctgt
      721 tgttgtcccg ctgacaagcc aatgccaaaa cgatccgtat ctttactgat aacttcacta
      781 atcgtttctt gcagaacaga caaaggaaag gcccattttt tcgattcgat gattcgaacg
      841 acaccatatg cttgacggcg caaagcatat ggatcgtttg agccacttgg gatcatccca
      901 actgcaaaga aagaaaagat actatctaat ttatcagcaa tcgctaaaac agaacctact
      961 gtagtctcag gtaaatctcc ttcactggat ataggcatgt aatgttcacg gatcgctgtt
     1021 gctacggctg gtttctcgcc tttaagcaga gcatattttt ctcccatgat cccttgtagt
     1081 tcagggaatt ctcctaccat gttggttact agatcaaatt tatagatttc agcagcgcgt
     1141 tgcagatcca tcaattcttc ctcagatagt cctacttgtt cgcctatgat gcgagcgatg
     1201 acttgtaccc gttgcatttt ctcatagatg ctaccgattt tttcatggaa agtaacagtt
     1261 tttaattttt caacgtattg gtcgattgaa gctttcttgt cttcattata aaagaattcc
     1321 gcatcttcta aacgagcagt caatactttt tgattgcctc gtaccacatt ttccaatttt
     1381 acccgatcgc cattacgagc agaaataaaa tgaggaagca acataccttg atcgttccgt
     1441 acttcgaaat aacgttgatg ttctttcata gaagtgacta gtacttcttc aggaacagat
     1501 agatattttt cttcgaagtc gccagaaaag acagttggat attcgactag attgttgact
     1561 tcttctagta aatcttcatc tagatcaatg atccagtgat ttttttctgc taattcgttt
     1621 gcttgtgtga tgatcatttc ttttcttttt tgcggtgaag caataacaaa ttgttcattc
     1681 aatttttctt cgtattcttt tgcatgcgta aatgtcacat cttcgcctaa gaaacgatga
     1741 cctcttgaaa ctctgtctgt tttgacatcc aagatctcaa acgggattat ttcgtcatct
     1801 aacaatgcca cgatccagtg aatagggcga atatattcaa aatcgtattc tgcccagtgc
     1861 atcgttactg ggaaagtgag gcttttaatg acatctgcta aacctgtcaa tacttctttt
     1921 gcttctttgc cgtgagtgta tttcgttaca tagacatatt ccacgccttt taattctcta
     1981 aaagtgatag catctgtcgt cagaccttgt ccgcggacaa atccttcagc tgctttcgtc
     2041 cagtttccat ctgcgtccaa agcaattttt ttggctggtc ctttgacttc ttcttcgctg
     2101 tctgcttgac gttctggaat gtttgttact ttgattgcta agcggcgcgg tgtagaaaac
     2161 gtttcgatcg tatcataagt caattggttt tcatctaaaa attttgctgt tttttcttct
     2221 aattgtttca tgcttggtgt gactacatga gcaggcattt cttccagccc gatttcaagt
     2281 aataagtctt ttgccatctt attcagcctc cttcacgttt tctggatttg ctgtgttttt
     2341 attcaataaa gggaatccta atttttcgcg ttctgccaca aagattttgg ctacagcacg
     2401 agccatgttg cggatacggg aaagataacc tgcacgctct gttacggata ctgcaccgcg
     2461 agcatctaat aaattgaatg tatggctaca tttcaaaata taatcatacg ctggatgaac
     2521 aagattttca tcgatacagc gtttagcttc tttttcaaaa cgatcaaaat tgcttagtag
     2581 caggtcttgg tcgcttactt caaaagaata tttagaatgt tcatattctg gttgtttgaa
     2641 gatctcacca tatttcacgc catcagccca ttccagatca taaacacttt caacttcttg
     2701 gatataagaa gcaagacgtt ctagtccata agtgatctca gaagtaactg gtttacaagg
     2761 tagtcctccg acttgctgga agtacgtgaa ttgtgtgatc tccatcccat caagccatac
     2821 ttcccagccc acaccggcac aacccatcga tgggttctcc cagttgtctt caacaaagcg
     2881 aatatcgtgt tctaatggat caattcctaa aagacgcaag ctttctaaat aaagctcttg
     2941 gatattttca ggtgaaggtt tcattacgac ttgaaattga tgatgctgat acaaacggtt
     3001 tgggttttct ccataacgcc cgtcagctgg tcggcgggat ggctctacat aagcagcatt
     3061 ccatggttcc ggtccgattg cccgtaagaa tgtatatggg ctcatcgtac ctgctccttt
     3121 ttctgtatca taagcttgca tcagcatgca gccgtttgat gaccaaaatt tttgtaatgt
     3181 taaaatcata tcttggacgg tcaatttttt actcatctgt tttgcccctt tcaattttta
     3241 agcgttgctg tcaataagaa tacaggaaag aaaacgacaa aaagtcccta tgtctgatta
     3301 cagacatagg gacgaataat ttcgcggttc caccctactt ccgaataaag attcggcagc
     3361 ttcatttatc gtactcgcaa gtgcctcttc aaaaatcgtt tgggtccggc ttccactctc
     3421 ccgaactcgc taaaccacgt gttttttact gatcttggtc aatgtacgta ttcattttgc
     3481 agttttctgg tttgtataat agatcctctc agtgaacgat ctatttaatc tacggttaat
     3541 aatagacgga agtccctgta tttgtcaaat agttttgatt tttttgttgt atctttcatt
     3601 tattcttctt tttcaggtat ctctttttca ggcatatttt tctctggcgt ctttaatacg
     3661 tgtgcccaag acttcatttg atcaatgaac tttttgcttt ttagatgaat accgacatat
     3721 tcatcataca actggtcaat gaggtcacgg attgcctgct tcgtttcttc tttcaagtgg
     3781 attccactga tcttatcata agaaatagcc gaaaacattc gaacgaaata aacagcgcga
     3841 ggatctgcat gataacggtg ttcgtccatt ggccagtgtt tctcgcatat cacaccgcca
     3901 tatttggaag aatagtcaaa ttttcctttt gtttccccgc atacgacaca gtgcgtccaa
     3961 attggcgcga ttccgaagcg ttgcagtatt tgcacttcaa agatattcgt gatgatttct
     4021 gcatcatctc cttggtccat ccgctgcaga gcttgttgcg taaattggaa taaatgcggg
     4081 tcatattgat gatcttcgat tgctgcatct actagattta gcaaatacgt accataaccg
     4141 ctcaaaaaga tatcttcttg gatgttccga aacgcatgga cgtctttgac actgcttaaa
     4201 aacgacaaac cttcacttcg aaaattaccg atatagactg cttcggtaaa ggggagcaaa
     4261 gccggagcta atggctgatt ttgccgatgg attcctttga tataaaacat cattttgcca
     4321 gaagattccg taaagatttt gactaattta tctttttctt tgtaattacg gctagataaa
     4381 atcaagcctt tcgattctac aagctggctc atattctccc tcctaaaaaa taaatctgga
     4441 aaagcagatt ctgccgatcc agattattta tgtttcgatc ttccgatgtt tttctcaacg
     4501 tacggatttt tatccagttt atttctatac ctaacctata agaagtccag aatatcagta
     4561 ctcgtctttt cggtagccga agtcttgcag atagactttt ttgtctcgcc agtctttttg
     4621 gactttgacc caaagttcta gaaatacttt gtctcctaaa agattttcga tatcctttct
     4681 tgctttcgtt cctacttgct tcagcatttt tccgcctttg ccgataatga ttcctttttg
     4741 gctatctctt tcgacgatga tcgtggcctg gatatggatt ttatcattct cgtttcgctt
     4801 catcgaatca acaacgactg cgacagaatg aggcacttcg tctcgtgtta aaaacaagac
     4861 tttctcacgg atcaattcag aaacgatgaa gtattcagga tgatcagtca cttgatcatc
     4921 tggaaaatat tgtgggccct ctggcatttc actgactaat acatccatta agcgttcgac
     4981 attgtttcct tctgtagcag agatcggaat cacttgtgca aaaggcatct gcgtcgaata
     5041 atcttcgatg attcccagca actcgtctgg atggatctta tcgattttat tgataatcag
     5101 ataaacagga gaatgcacgt tttttagacg ttcaataata aaatcgtctc cccggccacg
     5161 tttttgatca gcactgatca taaataagac tgcatccact tctttcaacg cactgtaagc
     5221 tgcttctacc ataaaatctc ctagacgatg ctttggttta tggattcctg gtgtatcgat
     5281 aaaaatcagc tgagcttctg gtgtagtata tactccttgg attttatttc tagttgtctg
     5341 tgccttgtca ctcataatgg caattttttg acccacgatt cggttcaata atgtggattt
     5401 tcctacattc gggcggccga cgattgcgac aaaccctgat ttatgttctg gcatatacgt
     5461 tctccttttt aattaaacaa caaatgatat attttaggga caaataaaat caacccaatg
     5521 atgacagcaa aacaagcggt cactaaaact gctccagctg ccatatcttt gatttttttc
     5581 ccaatcggat gaaaatgaaa atccgtaaac atgtccacta cattttcaaa aacagtattg
     5641 atgatctcta ctatccaaac gagaaaaaca gctaaaagca gccataacca ctctatccga
     5701 tcaagctgga aaatcacgcc cataaataaa gcaaggatac cgaacgcaac atgtttcctc
     5761 atattgcgtt cttcctcaaa aacggttttg actccttgga cagcaaattc cacagacatc
     5821 aggaaatgtt tgtttttctc tacgttttta tcttttgagt ccataggcat ccaagatctc
     5881 tttctgtaaa ccaaacattt ctttctcatc ttctggtgtc atatggtcat acccgttgat
     5941 atgcaaaaat ccatgtaccg ctaaaaagcc aagttcccga tcatatgaat ggccgtaagc
     6001 ttctgcttgt tcagcagcac gttcaataga gatcatgatg tctcctagta cacgaggtaa
     6061 tggattctct ccatcttcaa aaatcactgg gatttcgtct tcgccttctt cttccagagc
     6121 aaaactgatg acgtctgtcg gtgcatcttt tccacggtaa tcacgattga ttacttgaat
     6181 tgccgcattg tccatgaaag taacagacat ttctgtttcc tctggcagct ttaaataaga
     6241 tgctgcaaat tgcagcaagt catcgatttc tttcattttc tcttctgaga cttggtttgt
     6301 ttcatccata aaggtaatat ccattataca tcgcttcttt ctattcttct tgtacttcct
     6361 ttatcttctc aacttctgtt ttcattttag gatatttgat ccgagaatgg aaggtgctac
     6421 ttaaaccgct gattaatgat ttttccactt ttcggatttc tttcaaggtc agtccactat
     6481 cgtctaattg accatcggaa atacgctctt cgataagatt atggacaaaa ctttcgattt
     6541 tttcgctcgt cggatgatcc attgcccgta ctgcagcctc acaactgtca gcaatattga
     6601 cgatccctgc ttcacgactt tgcggttttg gtccaggata acggaattgc tcttctgtta
     6661 cttccggatt gcgttctttc gctttgatgt agaaataacg cattagcgtg gttccatgat
     6721 gctgtttgca aatatcgatc accatttgcg gcatattata atcttccaat attttggctc
     6781 catctgtcac atgtccaaag ataatatgtt tactgtcttc tggcaataag aaattgtgcg
     6841 ggttttccgc tcctgaaggc aagttttcaa cgaaaaagct agcatgtttg atcttgccga
     6901 tatcatgata atagcaagct actcgagtta gcaaagaacg tccgccgatt tctgctacag
     6961 cgttagcact tagattagct accatcatac tatgatgata agtacctggc gcttcttcca
     7021 gcaactgttt caataaagga tgatttggat tgctgagttc atttaataca attacactgt
     7081 catcattgac catcaattca atatatgggt gtagaccgat cgtcagcaag aatgagaaga
     7141 gtgcaccagt gaacccgcag acgagcatta accaagtcgt tgcatcacca aagctcattc
     7201 cttgatagac gatcaaaatg acatccatca tcacaggaaa aataatgacc cacatggcag
     7261 cagataatcc ttgttctgag atccgtttgc gtctgacaat cgttgccatg agcccagaga
     7321 aaacataaga catcaagata atcgttagaa agttcgtgcc aatcgaatca taaaaaatga
     7381 aaagtgcgga tactgcttgg aaaataccag ccatgatccc tgctcttcga ttcaagaaaa
     7441 agcttaaaac aagtggtgca aaagcagcgg gataaaacag cgggatataa gtagcttgtt
     7501 ccgtttggaa taattggaaa aatttcatca gcactatgct gactgacata gctgtcacat
     7561 agaaaagcac gtattttgtt ctttctcctg cattttggaa ttgaagtgaa ttataaatca
     7621 gtacgccgat ttgaagcaaa acagctaaaa ccatggcaat tagcggaaaa atcgaagttg
     7681 tttgattagt cagtcctagt aattccaatt ttttcatagc tgaagcatcg atttgattac
     7741 cttcacgaac aatgatttct ccttggaaga tcatcactgg ttgtacagct tctcgtgcgg
     7801 attgtttcaa ttcttctgtc tttttctcat tcaatacgtc attcactacg ataccttgat
     7861 ccactaagta gcgaatcatt tgttgttgtg ctggtgtgac attcaaatat tggatttgct
     7921 cttctgcttc ttgtttaaaa gcttccaatt cactttcacg aacttgtttg ctcatctgtt
     7981 cgtcaatgag cttcagactc tcatccctca cagtatgaat ctcagtttca gtcatttcaa
     8041 atatcgtcga ataaaaattg ttcggtagtt tttgataaaa cacaacattt tctgcattca
     8101 cattttcaaa atttttcttc agcgcggcga tccgctcttc tgtagtaggc tttgggatat
     8161 tttcatcttc ctttgcctta tcaatctttt cgtcataaga tttgttgatg gcatcattcg
     8221 tcttatcgat caattcaaat agttgcttga tccgattgtt ctggtcatct gcaagatctt
     8281 tttggtaagt gtattctgga gtgactgctt ctgctgccag ttttcttttt tgttcggttt
     8341 cttccgtgtt ctcgatcgtt ttgttcgcac ggatactttc ttctgctact tggccttctc
     8401 tgaaatcatt ggccttttgt ttgacactac taaatgtaac gccgcagata atgataaaaa
     8461 acaagaacag caggaaaggc aatgctgcct ttccaagttt ttcttgtagt ttctgcagtg
     8521 ttttattcaa catgtgctta tcctcctaag caaagcttat tcttgatgga gatctgcctt
     8581 ttcataagct ttgatgattt cggcaactac agggtgccga acaacgtcac ttgcttcaaa
     8641 attaacaaaa tcgattttct tgatttgctt taatgttcgt tctgcatgaa caagaccact
     8701 tgtcgtccct cgaggcaagt ctatctgact tgtatcccca ttgacaatca tttttgattg
     8761 ataaccgaga cgggtcaaga acattttcat ctgagcgact gtcgtgtttt gtgcttcgtc
     8821 caagataacg aatgcatcat ccaatgttcg cccccgcatg taagctaaag gtgcgatttc
     8881 gattacgcct cgttccatca atcggttcgt atgatccaat ccaaaaattt ggtataaagc
     8941 atcataaaca ggccgcagat aaggatccac tttttctttt agatccccgg gaagaaagcc
     9001 tagattttca cctgcttcca cagcaggccg cgtcaaaatg attttttgca cttcaccttt
     9061 tttcaaggca gcgattgcta atactactgc aagaaaagtt tttcctgtcc cggctggtcc
     9121 tacgccaaat acgatatcat gtttggctac cgattcgaca tatttctttt ggccgctgtt
     9181 ttttacccgt ataggttttc cattacggtc tttgacgatc tcttcctcat acatctcaac
     9241 aaaataatct aatgtacctt tttgccccat tttcaatgcc gtcacaacat cgggcgtact
     9301 tacgtggatt cctcgtttga tcaattcctg taatgtccga atgactgagg cagccaagga
     9361 aatctgggat tgctcaccaa tgatctgaat gatttctcca cgtgtatgga tggttgtttc
     9421 cgttgtttcc tcaatcagtt ttatatgctt gtcgtgtgca cctaaaagca tgctgacatc
     9481 atcagcagcc gtcaatctaa tctctaaaga actagactct tccgtcaaaa atagacatcc
     9541 cctttttttc gattaattct ttcctatttt accatactca gaagaaacta tatagcaaat
     9601 aagaaaaggt tctaaaagag ttgcttaacc ataagtacca agaaacgtta aaaaactagc
     9661 cgcttccatt ctctaaaggt ctcgtttgaa taaaaaaagc tgatcatgta agctatgcat
     9721 aagatagagg acaagtattc cgtctaactt agcaagtatt ctctgggtat ttttcttgtt
     9781 tcaaaaaaag aaaacaaaat atttgaaata ttcttgcatt tcaaaaaaaa caggtgtatt
     9841 ataacgtcaa caaataaata tacagcaaag cgtcgaggaa aacagtaggc tattcagtga
     9901 tttattccca gtgagtcatg taagtgagaa atgacaataa atcgaataga cgaacatcat
     9961 ttccgagtca atgtcgaaaa cgtagatcat tgtggctgcc tccattatca ggctagcgga
    10021 taactttatc gaaaagcgtc cgtgaatgaa gaagcttttt taagcgaaaa aaggtggtac
    10081 cgttctagaa tctagagccc ttttcccaag tggaaaaggg ctttttttat attttaaggt
    10141 ggtggttttc atggaatctg atattagtgg tatttctagt ttctgcaacg tttattttgt
    10201 tactcaaaat gataattatt ggaggaaaaa tttatggaag aaacaaaaac ttattcatgg
    10261 aagcaattat tgatggtcag ttcacttatc ttcgggatgt tcttcgggtc aggtaatctg
    10321 atctttcctg tacacttagg tcaaatggct ggatcaaact ggatcagcgc tggtgtagga
    10381 tttgccatct caggcgctct tttcccatta ttagctatct tagctgtagt agtgacaaaa
    10441 agtgatggtc tgtatgactt agctaaacct gtcggaaaat ggtatgctgc cttgttcttg
    10501 atccttgttc atttaacgat cggaccattc tttggtacac cgcggacagc agcaactgct
    10561 tttgaaatgg ctgctaaacc ctttttgcct gaaaaatatg attcattagg tatgttttta
    10621 ttctctgctc ttttcttttt acttgcttat ttccttactg tacatccaac acgtttggtc
    10681 aaatatgtcg gaaagtattt aaactccttg tttcttgcat tattagctat catttttgtc
    10741 gtttctttat tccaacccat ggggaatcta aaccaatctg ctgcagattc ttatcagacg
    10801 aacgctttga caaatggcgt tttagaagga tacaacacgg ttgatgcagt agctttactt
    10861 gctttaagtg tcacttttgt ccatgcagtt cgtgatcttg gttttaaaga taaaaaagtc
    10921 acagaattaa cagcaaaagc tggtagcctg agcgttgcgt tagaagtcat gatttatttt
    10981 ggtctggtcc ttctcggtgc gatgagtttg aataagatgt ctttatcaga aaatggcgga
    11041 actgcacttt ctcagatcac taatttttat ttaggtaact tcggtgctag cttcttaggg
    11101 gtaatggtca cattaggtgt cttcactact gctatgggac tcgttgtttc ttttgcacaa
    11161 gatttccata aactgttccc taaagtcagt tatatgacat ggctgcggtt aacgactttt
    11221 gtctcttttg tcgttgcgaa tgccggattg gataatatca tccaatggtc tttaccagta
    11281 ttgatgcttt tgtatccatt gtcacttgcg ttaatcttac tttccttaac agcaaaattc
    11341 ttccaaaaga gtccatttgt ctatcaagta acgatgttct tttctgccgt tccagccgta
    11401 ttggatatgt tggcaaattc gcctgcatta gtgagtcagc aaactgtcgt agcaagctta
    11461 ctaggatttt atcatcatta tgttcctttt gctgcattag gtcttggctg ggtcgtccca
    11521 acattgcttg gttacgctgg cagcttgctc ttttattatg tatatcgcgt atcaggatat
    11581 aaacaagaag caagtgagtt accagaagaa taaccaaatc aaacacaatt taacataaga
    11641 gatattaaac aggaaaaaaa cagctagaag aaagaatggc tctataattt atgggactga
    11701 tgaatcagaa ttgattcttc agccccattt tcattttagg
//
LOCUS       DACGMI010000084        11135 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.087, whole genome shotgun sequence.
ACCESSION   DACGMI010000084 DACGMI010000000
VERSION     DACGMI010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.087"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(198..1181)
                     /locus_tag="IXT46_002615"
     CDS             complement(198..1181)
                     /locus_tag="IXT46_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAQ4948503.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(1186..1833)
                     /locus_tag="IXT46_002616"
     CDS             complement(1186..1833)
                     /locus_tag="IXT46_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4948504.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(1918..2550)
                     /locus_tag="IXT46_002617"
     CDS             complement(1918..2550)
                     /locus_tag="IXT46_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4948505.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(2566..3117)
                     /gene="coaC"
                     /locus_tag="IXT46_002618"
     CDS             complement(2566..3117)
                     /gene="coaC"
                     /locus_tag="IXT46_002618"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAQ4948506.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(3114..3851)
                     /locus_tag="IXT46_002619"
     CDS             complement(3114..3851)
                     /locus_tag="IXT46_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAQ4948507.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(3848..4837)
                     /locus_tag="IXT46_002620"
     CDS             complement(3848..4837)
                     /locus_tag="IXT46_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAQ4948508.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            5095..5637
                     /locus_tag="IXT46_002621"
     CDS             5095..5637
                     /locus_tag="IXT46_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4948509.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            5654..6739
                     /locus_tag="IXT46_002622"
     CDS             5654..6739
                     /locus_tag="IXT46_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4948510.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            6751..7557
                     /locus_tag="IXT46_002623"
     CDS             6751..7557
                     /locus_tag="IXT46_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4948511.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            7558..8385
                     /locus_tag="IXT46_002624"
     CDS             7558..8385
                     /locus_tag="IXT46_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4948512.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            8382..9455
                     /locus_tag="IXT46_002625"
     CDS             8382..9455
                     /locus_tag="IXT46_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4948513.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            9883..>11135
                     /locus_tag="IXT46_002626"
     CDS             9883..>11135
                     /locus_tag="IXT46_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4948514.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNE"
BASE COUNT         3427 a         2010 c         2279 g         3419 t
ORIGIN      
        1 cggaaaaaga gcgtgggaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat
       61 aaacggcgga agcagaagaa attccttcgg aaataagctg aaattcacaa aaatttgaaa
      121 agcaattttc gtgaatttct tcttatttct tggagttaaa cgcttctgtc ccagcctctt
      181 ttttgatcag catgatttta ttcagttatc ttcaaaatga tttttccgat gtttttgttt
      241 gcttccatat attcatgcgc ttgtttgact gcgctgaatt ggaatgtacg gtcaatgatt
      301 ggccgaatct tgccattttc tagaaaaggc ccagcttttt gcataaaagt ttgtgcgagc
      361 tctgctttat actgatcact tctaggtgtc aataatgtac caagcagttg gacacgtttc
      421 ccaatcaata caccaaggtc tatctcaggc acgatggtcc cacctagcat accaatcaag
      481 acccaacgtc catcaacggc tatagaagct aaattctttt cccagtaaga agcgccgatg
      541 aaatccaaaa taacatcgac tccccgacct tcagtgattt ttcgtacctc ttcttgaaag
      601 tcttgttttt tatagttgat caattcatct gcaccaagtt ctttacaaaa ggcgagtttt
      661 tcttctgatc ctgcagtaac gatgattttc gcgtgagaaa gctgtctagc taattggatc
      721 gctgctgttc ccacaccact tgctcctgca tggatcaaga cagtttcgcc ttcttgtaat
      781 tttccaagcc agtaaagtgt ttgataagca gtcaaaaaaa cttctgagat tccagcagca
      841 gaaacatagt ctagcgtatc agggagaagg attgcacgat cggcaggcat cacagcatat
      901 tcggcataac cacctagatt gactaatccg tatacttttg tcccaggagt aaaagtggag
      961 atatcacttt tattctcaac tacctctcca gctacttcga ctcccaaaat agggtaggga
     1021 ggtttcaaag agactgattc tcttttcata atatctgttc gattgacagc tgctgtatgg
     1081 actttgatca gtaattcgcc ttgttttggt ttaggaacag gcacttcaat ttgttctaat
     1141 acatctacag aaccaggatg cttgattgaa atggcacgca tggatctatt cctcctttgc
     1201 ccattcttgg aatgctgtat tcaactcttt gctaccttca gaaagtacta gagtcgtacg
     1261 agaaatatcc gtttcttcca ctagagcggc aagtacagca gcaactgtag agcgagtgat
     1321 cgtttttgat gccttctcat taggcttagt taattgaatg gaagtaactt cttcatcgtt
     1381 agtcaatgtg actggttgaa gaatgacaaa atctaagtta gttcgtttca gccattcatc
     1441 tgcataatgt ttagtaatat aataatctgt catggactca ggccattttg ctggttcatc
     1501 tgcataaaca gcactgacca tcagatagcg agagacatgc gcattttcag ctgcgatcac
     1561 tgttttgatt gcgccatcca agtctacttg cagaagattc tttccttgag agccggcagc
     1621 aaaaatcaat acatcgatgc ctttgaatgc ttcggtcatt ttttccacgg accaagttaa
     1681 atcaaaagag acatacgaaa cattctcttt ttttactaat gtttgggaag caacatctct
     1741 cacccctgca aaaatttcat gggaacttgg agctaaatct tttatcaggt gtcggccaat
     1801 ttgtccgttt gcacctacaa caaaaatttt catttggatc atcctttcga cgtcaaatct
     1861 ttccattcaa tagtaacacc aaaagagaaa aaaatcagag atcggctacg atgactatca
     1921 gttagtaaga gaagggtgct tgaagtatct taacaagaca ttgcatactg ctgcagtcgc
     1981 aagacctgcg acgattcctt caggtatacc acttgtaaaa ataaccgcta gaatagctga
     2041 ataaacagca tttaaatttg ttccgatgac tttggcataa tcttgctgga ataaaaagta
     2101 gatcatattc atcactaaaa tcgtattggt caatgaaccg gaaagtccag ctaagaataa
     2161 agaaacggaa tctgcttttt gtttcattag tttgcgcaga cctttataaa cgaaataagg
     2221 aaccacccca atcaagatgc gaggaataaa cgcgatcagc aaggctttcc agcttccatg
     2281 ttctgttccg atgactggga taaacggaga aaagacaaaa gacaaaggtg tttggataac
     2341 tgtgctacgg atcatgctga tcagtccaaa tgtaccgcca agaaaagcac ctagtcttgg
     2401 tcctaaaacg atcgaagcaa tgattacagg aatatgcatg gttgttgcat tgattggacc
     2461 gatagggata aaacctaaag gcgtaacagc taataaaatc aaaatagcta aaaacatcgc
     2521 agttaatgta aagttttttg tatttttcat aagtactcct tttttctaag catttctttc
     2581 attaagagtc agcatgacct gttcgatgat cgtctgaata tcagctaagg caccttttcc
     2641 aaaatctcca caagctaaaa gagattctct tggttcaatt tcctgatagc cgacagatct
     2701 caatgtttcc agattacgct gagtgatcgg gttttgatac atattcgtgt tcatggcagg
     2761 ggcaatcaat tttggtgttc ccactggaag cgccattgcg actgttgaaa gaagatcgtc
     2821 tgcaatgccg tttgctagct tgccgataat gtttgctgta gcaggcgcga tgagaaacaa
     2881 gtcagcttgt tttgctagtt cgatatgatt gattacctgc ggatttgatt cttgcatgac
     2941 gtctgtatgg actgcgcgct tcgacagaga ttgcaaggtt aatggcgtga taaaatgtgt
     3001 gctgctttta gacataatca catctacctg ggcacctaat ttgacgaatt gacttgtaag
     3061 atcagcgctt ttgtaagcag aaatacttcc agtaacgcct agtaagatct ttttcatttt
     3121 gattcctcca gtctaatttt ctcagtaatc aatgcagcaa tctcagattt actttgagct
     3181 tcttccactg ttccatcttt agataagaga tagccgtggt gtgtctcgcc atggatttcc
     3241 gtcaaatcat ttgcgaaaat aaaatcagtt ttgttattta tcagactatt ttttgcgact
     3301 gccagaagag attcctttgg tacatctact aatagtttga aaccaatgat ttttgctttt
     3361 ggctgccatt cacgtagata agaaatgatt tttggtgttt tcttcaaaac gagcacaaga
     3421 tgctcggtgt tagaagagat ctttgaaaca gtggtatctg tctgttcatt ttccgcaaac
     3481 caattgtcca gttcttcttg cgttgaagaa gtgggtaggt tttttgccag ctgttcttct
     3541 gaaaaactaa aagcaggagt aaaatcactg actgccatac tgtggataat cgcatcgtag
     3601 tgttcttttt tcgttagttc ttctaattgt aaaaataagt ccagtgcaga ttcgatcgta
     3661 taaatcgtta tattggagtg tcttttcggt ttcagtgctt gtttcgtagt cacgtaatcg
     3721 attgtggtat ccggattggc agctaaataa tcagctaatg cttgccctaa tcgtcctgtc
     3781 gaatgatttg taatagcacg tacttgatcg attttttcag tcgttcctcc agctgtgatt
     3841 agaatcttca tttatggtca cctacattta ctagtgttct tccttggtgt gttccagcaa
     3901 gtagtttaga tgctgtttca ggcaattgat ccagagtaat ctcttggacg accagttcat
     3961 ctgcaatctg caaatccgcc atctgttgcc ataaagaaag acgttgatct attggtacat
     4021 tgacagaatc aattccaatc aactggatgt ttcgcagaat aaaaggcaag acagtcgcgt
     4081 ttagtttgat tcccccagca ttgccacata aagctactgc accgttataa gagatcaatg
     4141 gaagaagact gcttagctgc tcgccaccta ctgtgtcgat gacatagtcg atttgctgtt
     4201 ttcctaaagc ttttgttgtc tctggcagaa attcatcagg tcgtacgact tgcaaagcac
     4261 ctagactttt tagccatgtg acagactctt cttttctgga aaaggcaatg attgactgga
     4321 atcctagttt atgtaacagg gctatcgctg tactgcctac accgccagaa gcaccagtaa
     4381 cgacaacttt tttatcggag gtcatacctt gacggattaa agcgttcaca cacaacatag
     4441 cagtaaaccc tgctgtacca aggatcatcg cttgacgcag cgtcatattt tttggtagag
     4501 gaactaacca gtctcctggt actttttgat attggctata accgcctgga tgggtgacgc
     4561 caagcccaaa accagtagca agtacaagat cttcttttga aaaacgtgga ttgttacttt
     4621 ggacgacagt tccggataaa tcaatccctg gagtcatcgg atatgttcgt atcacctgac
     4681 cagactcgct cattgccaat gcatctttat aattgacatc agaataggca atttttacca
     4741 agacttcatt ttcagccaac tcagtaaatg gcagatcact gattgctgta tggaaaacag
     4801 gttcctttat tacctgaaaa gatcgaaaag cgttcattcg tgagacactc cttttaaaat
     4861 tttcttttat cataccataa agcctactct tttattcttg ttcttccgta aatttagaca
     4921 aaaattaggt gaaaaataaa gaatcaaaca actagaattt attccaaaag ataaagaaat
     4981 attcagcaaa aaaaatttta caaagggttg cctttttcaa taaatttcgt atactaatac
     5041 gagtggtagt aaacaggaag tttactatta gaaaacttcg attcggagga aattatggaa
     5101 attggtgaga agttaagaaa tttgcgcatc caaaagaatt tgacacaaga agaactaggc
     5161 gaacgcacag atttgtcaaa agggtatatt tcccagttgg aacgagattt aagttcacca
     5221 tcaatggaaa cattcttttc tattcttgaa gtcttaggtg tgactccaga agaatttttt
     5281 catcaagaag cagcgaatct gcaagtggtt tattcaaaag aagatcatac ggtttatttc
     5341 gatgaagaaa acgggtatga attggaatgg ctcgtggctg attcgaatga aaaagaaatg
     5401 gagcctgtct tgctgacttt tgaaggtgca ggagaatata agacgtttga accttcatta
     5461 tctgaaacgt ttatttttgt attagaaggg gaattagagt taagcttagg agagacggtc
     5521 tatgtggcaa aagcaggaca gtcgatctat tatcaagcga caaaacaaca tcaattaagg
     5581 aatcatctca aaaaacgaac aaaagtattg attgttgcaa cgcaatcata tttgtaatat
     5641 agggggtaaa aacgtgggga aaccaatcat ttcatttgat caagtagtga aacgctatga
     5701 tgatgaaaca gtattaaaaa aagtaagttt tgagatcgaa caaggaaaat tttatacact
     5761 gcttggtcct tccggctgtg gtaaaacaac gatcctacgt attatagctg gattcaccga
     5821 agctacagaa ggggacatct attttgaagg gaaacggttg aatgatttgc cagctaataa
     5881 gcgacaagta aatacagtct tccaagatta tgcacttttt cctcatatga atgtttttga
     5941 taacgttgct tttggattga agatcaagaa aatgtccaaa tcagatatcg aaaagaaggt
     6001 aaaagatgct ttgcgtatgg tccagcttcc tggatacgaa aaacgggaga ttagtgaaat
     6061 gtctggtggt caaagacagc gtgtagcgat tgcacgagca attgtaaatg aaccgaaagt
     6121 attgctatta gatgaaccgt tatcggcgct tgatttgaaa ctacgtacag atatgcagta
     6181 tgaactgcgg gatctgcaac aacgattagg aatcacgttt atttttgtta ctcatgacca
     6241 agaagaagcg ttggcaatga gtgatgagat ttttgtcatg aataaaggga aaatcgtcca
     6301 aagtggtaca cccgtagata tttatgatga gccaatcaat catttcgttg ctgattttgt
     6361 tggggagagc aatatcgtgg acggtgtaat gatcgaagat aatctagttg agtttgttgg
     6421 taagcaattt gaatgtgtcg atggcgggat gcgtctaaat gaaccagttg aagttgtttt
     6481 acgcccagag gatttgacga tcacgacacc agataaagga aaactagtcg taacggtcga
     6541 tactcagctg tttcgtggtg tccattatga aatcatctgt tatgatgaac agcaaaatga
     6601 atggatggtc cattcaacga aaaaagctaa agaaggaagc aaagtaggat tggcctttga
     6661 gccagaagat atccatgtca tgcgtttcaa cgagtctgaa gaagaattcg atgcacgtct
     6721 tgacagctac gaagaatagg ggggacaaga atgaaaacaa tgcgcaggat ctattccgtc
     6781 ccttatattt tgtggctcgg tttattcgtg atcgcgcctg tattaatgat catttatcaa
     6841 tctttttttg atatgaatgg gcaattcacg ctgaataatt atctatctta ttttacgtcg
     6901 gggacatcgc tttctatgac gatcaattct gtatggtatg catttttgat cacgtttttc
     6961 acgctgatca tcagttaccc gactgcttat tttttaacaa aactgaagca caagcaatta
     7021 tggctgatgc tgattatttt gcctacatgg gtgaatctgc tgcttaaagc ttacgcattt
     7081 attgggattt tcagtgtgca cggcagcgtg aatcatttct ttgattttat cgggatcggg
     7141 ccgaaacaga tattattcac agacttcagt tttctgttcg tggcaacgta tatcgagatt
     7201 ccatttatga ttatgccaat tttcaatgca ttggaagaga tgaatccttc tttgatcagt
     7261 gctagtagag atttaggcgc gaatagcttt gagaccttcc gacgagtgat ttttccgtta
     7321 tcattaaatg gtgtgaaaag tggtgtccaa gcagtattta ttccttctct ttctttattc
     7381 atgctgactc gtctgattgg cggaaatcgg gtgatcactt taggaacggc tatcgaacag
     7441 catttcttgg ttacacaaaa ctgggggatg ggttctacaa tcggtgtgat tttaatcatt
     7501 gctatgttca tcgtgatgct cctgacaggc gagaagaaaa aaggaggtcg ctcataaatg
     7561 aaaaaattta aatggtcgta tctttattta gggatcgtct ttttattctt atatgcaccg
     7621 atcttctatc tgatttttta ttccttcaat gaaggaggaa cgatgaacag ctttacagga
     7681 tttacttggg aaaattatga agctgttttt gaagatacac gtttgatcat tatcgtattg
     7741 aatacgttca tgctggcttt cttatctgca ttgatcgcca cgatcatcgg gacatttggg
     7801 gctatgggaa tctattacac gaaaaaacga cgtgcacgga cagcgttgtt gagcatgaat
     7861 aacatcttat tagtctctcc tgatgttatt atcggtgcta gtttcttgat tttctttaca
     7921 ctactaggat tcggattagg ttttcagagt gtattgcttt cccatattgc tttcagcatt
     7981 ccaatcgtcg tcttgatggt cttgccaaaa ttgcaggaaa tgaacgattc aatggtcgat
     8041 gcggctagag accttggtgc taataatttc caagtagtca aaaatatcat tttgccttat
     8101 ctttctccag gaatcatagc tggatatttt atggcattta cctattctct tgatgatttt
     8161 gcggttacat ttttcgtcac aggaaatggc tttacgacgc tctcagtaga gatctattct
     8221 cgtgcaagac aaggaatcag tttagaaatc aatgcgctaa gtgcgttagt tttcttgttc
     8281 tccatgatat tggtcattgg atactacttt attagtaaag aaaaccgtcc aaaacggctg
     8341 aagaaaaaca gaagagtacg cgagggggtg gcacggctgc gatgaaaaaa ttacaatctc
     8401 tgtttttagg tattctcatc attattgcgg tgctgctgct tggtgttcgt caacttgaaa
     8461 aaacaagtgg catgagtgga gcaaaggtac ttaccatcta taactgggga gattatatcg
     8521 atcctagttt gatcacgaaa tttgaaaaag aatatggata caaagtgaat tatgaaacat
     8581 ttgattctaa tgaagcgatg ttcacaaaaa tccagcaagg tgggacaaac tacgacatcg
     8641 ctataccaag tgaatatatg atccaaaaaa tgatcaaaga aaaactagta cttccattag
     8701 atcattcgaa gatcaaagga ttaaataata ttgatccacg atttttagac ttggattttg
     8761 atccagataa tcagtattcg attccatatt tttggggaac tttagggatc gtatataacg
     8821 ataaattctt tgatgcaaat caaattaagc attgggatga tttgtggaag ccggaattaa
     8881 aagacagttt gatgctgatt gacggtgcac gagaagttat ggggctttct ttgaatagtt
     8941 taggctattc tttgaatagt aagaatatgg cacagctgac agaagcagca aataaattga
     9001 atcatttaac accaaatgtc aaagcaatcg tggcagatga gatcaaaatg tatatgatca
     9061 atgaagaagc ctccgtggca gtgacatttt ctggcgaagc tgccgatatg atgtgggaaa
     9121 atgaacattt acattatgtg atcccaccag aaggatccaa tctttggttt gataatatcg
     9181 ttatgccaaa aaccgtgaaa aataaagaag gtgcctatga tttcatcaac tttatgctag
     9241 aaccggaaaa tgcggcacaa aatgcagagt atattggtta ttctacacca aatgaagaag
     9301 caaaagcgtt attgccaaaa gacatttcgt cggacgaaca attctatcca tctgatgaca
     9361 cgatctccca tcttgaagtc tacaaagatc taggatcgaa atacctaggc atctataatg
     9421 acctattctt agaattcaag atgtatagga gataatggca aaactcagta agaatgggga
     9481 cttatcaacg ttctaaagag ctaaaaatcg tcctttttct atctgagttt tccaatcttc
     9541 taccaaaagc ggatgaaacg ccgctttttt tgtgttattt tattttttct accacgtttt
     9601 tctaccagag aaaagtggac aaaaccattg taaaataggg cccgagacgg gctagtaaat
     9661 ctaagattga aaaagttaca gaaggataaa gtaattggaa actatgcaaa tatacttaac
     9721 ccttctgtaa tctattaata aaactaatat atgaatccag ttcaatattt gtagctatga
     9781 aaaaacataa aaatcatatt agataaaaac taaattggta gataaattat tttgtcagat
     9841 atctgaggca aatattcgac tatttgtgtt tcaaagtaaa aattggaata caaatataga
     9901 atagacatat tgcagccgat agtttattat gcttttagac acattaaact ggaggaaaaa
     9961 atgaaaaaga gcgctaaaga tcgagttttt gatgagctga tacgactaac agggaatatg
    10021 tcttctgtca ctgccgagaa aatttcgaag aatctaggta tctctcgtca gaatgccagc
    10081 cattatttga cgagattagt ggaagataaa aaggtcgaga aattaccggg aaagcctgtt
    10141 ttgtggaagc ctttagatga atatgcggtt gtagataata cggagcaaat aaacgaagcc
    10201 tttcattctg tagttggtca tgacggaagt ctgagagagg tcattcaaaa atgtatagcc
    10261 gctgtcaaat atccgcctaa cggactcagt gtattaataa atggagccac gggtgttgga
    10321 aaaagttttt tagccacaaa aatttttgaa tacgctatcc atgagcaaat tattgaaaaa
    10381 gatgcaccat ttgctatctt aaactgtgcc gattatgcgg acaatcccga actgctttcg
    10441 gcaacactgt ttggatacaa gaagggggcc tttacggggg ctgaaaagga taccgatggt
    10501 ttattggcaa cggccaacaa cggctatctt tttctcgatg aggtccatcg cctatcgaaa
    10561 gaaaatcaag aaaagctctt tctatttatt gatactggaa actatcgtcc agtcggtgaa
    10621 aatgtaaatt ggcattctgc taaggttcgt tttattttcg ccacgacgga aaaaggtgaa
    10681 aattatttat tagacacctt tgatcggcgt attcaaatta gtgttatgtt gccaactttt
    10741 gaagatcgcc ccattcgaga acgattagag ctgattcaat tattttttca aaatgaagcg
    10801 gatgttttac aaaaagatat tattgtttca agagaagcct tgtctttaat gttatctcat
    10861 ccctttagtg ggaatattgg taagctgaag aatatcatta aaatcagttg tgcggatgtg
    10921 tatagtcgaa cacaagaaga accattaacg attgggaaaa atgagatctt gattcagtta
    10981 aatatgctgg aatccgaagt agaaagcttg ccgattgcta gtttattgat aaagaaaaat
    11041 caaaagataa aaacggatcg aatcaaaccg tttgattatg attcgatttt ggaaaaaatt
    11101 actcagctga taaatgaagg taatttcaat gaaaa
//
LOCUS       DACGMI010000085        10718 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.088, whole genome shotgun sequence.
ACCESSION   DACGMI010000085 DACGMI010000000
VERSION     DACGMI010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.088"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..243)
                     /locus_tag="IXT46_002627"
     CDS             complement(<1..243)
                     /locus_tag="IXT46_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAQ4948515.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEK"
     gene            complement(236..1033)
                     /gene="recX"
                     /locus_tag="IXT46_002628"
     CDS             complement(236..1033)
                     /gene="recX"
                     /locus_tag="IXT46_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAQ4948516.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            1140..2522
                     /gene="rlmD"
                     /locus_tag="IXT46_002629"
     CDS             1140..2522
                     /gene="rlmD"
                     /locus_tag="IXT46_002629"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAQ4948517.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(2696..3274)
                     /locus_tag="IXT46_002630"
     CDS             complement(2696..3274)
                     /locus_tag="IXT46_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAQ4948518.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            3596..4066
                     /locus_tag="IXT46_002631"
     CDS             3596..4066
                     /locus_tag="IXT46_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAQ4948519.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(4174..5400)
                     /locus_tag="IXT46_002632"
     CDS             complement(4174..5400)
                     /locus_tag="IXT46_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAQ4948520.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(6154..6354)
                     /locus_tag="IXT46_002633"
     CDS             complement(6154..6354)
                     /locus_tag="IXT46_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4948521.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(6488..7096)
                     /locus_tag="IXT46_002634"
     CDS             complement(6488..7096)
                     /locus_tag="IXT46_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAQ4948522.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(7181..7651)
                     /locus_tag="IXT46_002635"
     CDS             complement(7181..7651)
                     /locus_tag="IXT46_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAQ4948523.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(7699..8613)
                     /locus_tag="IXT46_002636"
     CDS             complement(7699..8613)
                     /locus_tag="IXT46_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAQ4948524.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            8759..9562
                     /locus_tag="IXT46_002637"
     CDS             8759..9562
                     /locus_tag="IXT46_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAQ4948525.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            9740..10687
                     /locus_tag="IXT46_002638"
     CDS             9740..10687
                     /locus_tag="IXT46_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAQ4948526.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT         3303 a         2088 c         1729 g         3598 t
ORIGIN      
        1 cttttcttct ggagcatttg ctagctcttc aattgtagga aaccattcca tgaaacgata
       61 aaaataatcg atcactgtgt ctactctggt ttgctgaagc atgatctcag agatccagat
      121 acgataagga tcacgattat agcgccaagg caggtttctt ttttcttgtt cataccattg
      181 aatgaactga tcttgaaatt cttttgtttc tttatctgtc catttttccc attctttatt
      241 cactttcctc ttccttttcc gtaatgaatc gctggatcat atccaaatca aatccttttt
      301 gatataagct ttgctttact tttagatttc tttttttagg ttcaaacctt aaatttcttc
      361 gccatagttt atctccttgt ttgactaaat aatcatattc tatttcttga tctgcttctt
      421 gcggaagatc agctatcgct tgttggatca cttcttgaga aaagcctttc gtcatcaatg
      481 tttgttggat ttttctcaat aattcttttt ggctttttcc gtgatttttt ccaaacgctt
      541 tttcggctgt ctgatgtgca ttttgaactt ggtcttcaaa tgtatattgg ctgagcgctt
      601 gttcaatgat ttcaggtttc aaaccttttt gctgcatctg ctgcgctaat ttctttggtc
      661 ctttgtcact taagcgcata ttcgtgcgca cataactttc cccatagacc aaatcatcga
      721 caaggtccaa ttcttttaag cgggctacga ttttatttcg atcttcttga aggatttcct
      781 tttcttttaa gtatgttcgg atttcttttt ccgatcgcaa ctgataactt aagtaattca
      841 ttgctaggtg aaaaccgaaa tcagctccgc tactcttctt gatctcttgg atagtttctt
      901 cgtctaattc ccgtcctttt aataatcgat agcgtactaa tacatcttca gatacttgta
      961 aagcttctcc ttcagataaa tctacgcgat agaaagggcc tttgccttta ctgattctcg
     1021 taacggttaa cataaacatc ctcctcgaac atatattctc tatcatacca cagaaaatcc
     1081 ccgtaatcag gtattatatg ttagaataaa ccacagaaaa aagaaaaagg gagatactta
     1141 tggcagaaac aattgtcaaa actggacaaa cggttccttt gaaaatcaag cgtttaggca
     1201 taaatggtga aggaatcggt tatttcaaac ggttgatcat atttgttcca tatgcactac
     1261 caaaagaaga agtactagtg aaaatcacga aagcaactcc tcgctatgca gaaggagaat
     1321 taataaaagt caaaaaaaca agcaaagatc gcgtagtggc accatgtcct gtttactatg
     1381 aatgcggtgg ctgtcaatta caacacttag cttatcaagc tcaattggat tttaaaaagg
     1441 atctgctttt gcaagcattg gaaaaattca aaccagcagg ctttcgatct tatcaacttt
     1501 tgccgacgat cgggatggat gagccttggc attatagaaa caaagcacaa tttcagttac
     1561 gaaaaaataa gcagactcaa aaaattgaag ctggtttata cgaagcaaac tctcatcagt
     1621 tagtccctat aacagactgc ttggttcaag aacctcgaac acaaaaagta atgaatactg
     1681 ttgttcaact attgaataaa tttgatgcac ccatctatga tgaacggaca aacagtggaa
     1741 tcttccgcac aatcatggtt agaatcggtg ttaaaactgg ggagttacaa gttgttttta
     1801 ttactcgcag taaaaaattc ccgcaaaaaa acgcaatgat ccgtgagatc aatgaacgac
     1861 tgcccgaagt tgtttcaatc atgcaaaatg tccaggcaca aaaaacgtct ctcgtgatgg
     1921 gggatgaaac gatccactta tggggaaaag aagccattga agaacaaatc aatgaagtga
     1981 ctttcgatct ttctcctcgt gccttctttc aactcaatcc tcagcagacc gaattgcttt
     2041 atggcgaagg aatcaaagca ttagatgtcc agcctaatga aacgatcgtg gatgcttatt
     2101 gcggagttgg gacgatcggc ttaagtgtag caaaacaagc caaagaagta cggggaatgg
     2161 ataccgttcc tcaagcaatc gctgatgcaa aaaaaaatgc ggaaagatta ggatatcaca
     2221 acactcgata tgaagtcggg acagcagagc aagttctgcc taaatggttg aatgaaggtt
     2281 ttcagcctga tggtatcatc gtagatccac cacgtacggg tttggataac gcattgatcc
     2341 aatcattatt gaaataccct ccaaaaaaac ttgtttatat ctcctgtaat gtttctacac
     2401 ttgccagaga tctggttaat ttaagtaaaa agttcaagat tgaatattta cagtccgtcg
     2461 acatgtttcc tcagactgca cgttgtgaag ttgtcgtgaa gatgacgaga ctcgctgact
     2521 aaatgaaaga ggttgtgaaa aagtctgccc tgtatcaagt aataagaaca gccaaacaaa
     2581 aatagctctt catgttttat gaatactgta cttgtgaccg aagagttaac aggaggacac
     2641 tatttattta aaaaaagggt tgtgacatag tttttgtcac agcccttttt gattattatt
     2701 ggatattcac gtctatcact tgataaaatg catttgtcgt atcgctgata ttccatactg
     2761 ctaaaatcac attatatcct tttcgatcct gcggaagtgt gatcgtttgg ttgactgttt
     2821 ttggtggaac agttgctttg tcgtctattt ttgtgatcaa ttcaaaatca ctaaatttca
     2881 aaggttgatt aggattccaa gttggtttgg taatgtagta atcccaagta cttgtccgat
     2941 gttgtgctgt taaattccaa gtaatattta atgttcctgg attaaccatg tttttatgcc
     3001 atctgttaga tgtctgttca tctaaaggct caaagccgct gactcctgca ctagcaattt
     3061 ttccatcaat gaatgtattt ttggtagctt cgatactttg cggttcccat tgtgctcttc
     3121 cgacattttg atttaagttt cctgctgctg atgttcctag gtatgcacgg cttcctggag
     3181 aagtaatata accatgcgca aaacctggaa tgctaaaacc gaacaaccct aaactaacta
     3241 acccaataaa caataacgta ctaatctttt tcatgtagaa acctccttca tttgataacc
     3301 acattgtaaa cgctttattg tattaacaca aacattatgc ttttataatt ttatgttgaa
     3361 gtaaaaaagg tgaaaaaagt aagatgcaga ttataacaga agtagacgag aaaagtacaa
     3421 atagaaaaca tgagaatcaa atcatatgat ctttttcaaa aacatcattc atataaacaa
     3481 atgttcaact ttttaataac aacaattatc aatttttttc ttacttcaca aactaaatac
     3541 aggtcttgct gtgagccttc atggtaaact aatattatag aaaggagtta gtaaaatgaa
     3601 gatgataaaa gatattcgtt tttgggtttg tgttatagga attgtcatat taggcttttt
     3661 atcagggttg cttagcggaa atcccggaaa atattactat tctttgcaac ttccaccatt
     3721 tgcaccacct agctggatat ttgggccgat gtggacctta ctgtatatat tgatgggtat
     3781 ttctctttat ttgttactta atcacaacaa caaaaaacag cgaaacaatc ttgtcggtct
     3841 ttttgtgatt cagttcattt ttaattttat atggtctgct ctatttttta atttaagaaa
     3901 tattttcatt gcagcaatcg atattacact tttagttatt ttcttgtcag tgcttatgta
     3961 tcagttgtgg ctgcatcatc gcctggcaat gtggctcatg attccttatt atttatgggt
     4021 actattcgca actctattga attattcaat ttatttttta aactaagcgc taaaaagaga
     4081 cgtcctgtaa tttaacacat agaaaaagtg ccacctaagt tagatttttt gtctaattta
     4141 ggtggcactc tttattaacc aaactatttt tttctagtac ccacttgttg ttccatactc
     4201 attattctgg tcataaccat aaccattttg ttcctgtcca gcgtaaggat cataactttg
     4261 agtatcttga cttggtgtat agtactgact tgtatcttct gtttgctgat aataggtatt
     4321 cggatcttgg tactgatcat atgtgttttc tgaataggaa gaataatcgg tgtacccttc
     4381 actattcgat ccatcaccgt ttgtcgaatc gccatcttcc gaatcatcaa agaacatcat
     4441 tgaagcattc tcatttttca aattaggtaa tgtatcgctt gtttttatat ttaattgttt
     4501 cttcagttca ttttggatcg aaagaagatc attttttcct aaaatttgat agtagatatc
     4561 attgatcatt tgtccttcgc cttgcaactg gtcttgtttg attgtttcaa acgccggggt
     4621 gtagttcgtc gctacatcaa gcatgtcatc ccaatctaag tccgtcgtca cattgttctc
     4681 aactgctttt aaaatttttc tataattgct tacgccatct aaacttaaaa ctttattgac
     4741 gattttcgtc actacttccc gctgacgacg ttgtcgaccg atatcgcctt ctggatcttc
     4801 gtgtcgcatt cgagaatagg ctaaaccttt ttctccattc aatgtttgtt cacctactgg
     4861 tacatggaca ccatccaaag taaagtcaat tttattattc actttgatgc caccgaccgc
     4921 attgatcaaa tcttccatgc catccaaatt gatcgttaca taatgatcaa taggaatatc
     4981 gagcagttgc tcaattgaat ccatggccat ttcgacacca ccaaatgcgt aggcatgatt
     5041 taatttatct accgttccat aacctacgat attcgtataa atatctcggt ccaaactgat
     5101 gatcgttgat tttttttgtt tcggattaac tgttactacc atcatcgtat cagaacgtcc
     5161 ttgttccgtt cttcctaatc caccggtatc taaacctaat agcaaaaccg aaaaaggttc
     5221 tttgtcatca atgcttactc tctcagaacg tttggaggat attcgattag agtttttaga
     5281 aattttgttt actgtttggc tcgcttctcc cataaatctg attccgtatg ctgataatcc
     5341 ggcaatcagc aaaacgaata cccctaacaa ggttaataga actttttgcc atcgcttcat
     5401 aatacacctc tgtttcacat tttctaaaat attgtctcat ataactgttc aatcagcaaa
     5461 ttcacttttt aatcataaga aaactttaaa aaacattttt gtgtaacgat tattattttt
     5521 taaaatttct caaaattctt aactatcata ccataccgtg aaaaagatcg aaagaccgaa
     5581 tacacgcagt tcgcaatcgt tttatctttt tttatgtatt ttttccagaa aaagcgaaca
     5641 acaaggtatt ttccaaataa tcgtgcagta aaatgatcgc acataccttt cccatctttt
     5701 taacagtctt tgcctaccgt tcagattatc attcgatttc acgacaattt cttcctatga
     5761 ctggtccttt tgttaaaccc atcttctatt cgttttattt ccagctcact gcatggctct
     5821 taaaatgact cgaactagtg attgcattac catcatcttt taatggatag atatgctcct
     5881 cttcaaagta aaacgatttt cttttaaagt aatagaattg acatggtaat gagtatgtat
     5941 actagtggtt tcacaaatgg tcttttattc aacatccaaa aactgaaatt tctttaaaat
     6001 ccattactaa cgaagaaaat gttccttgct tgataattag ttaggacatg tcaagtgaac
     6061 aaatgcattt acttagccaa aaaatctaaa aacttcataa atagacaaaa agacacgact
     6121 ctctaagaag tcgtgtcttt attcaacaaa ttattataat ttagtcactt cagcagcttg
     6181 aggtccgcgt gcaccttcaa caatcgtgaa ttctacttct tgaccttctt ctaggctctt
     6241 gaagccgtct ccttgaattg ctgagaaatg aacaaatacg tcatctccgc cgtctactgt
     6301 aataaaccca aatccttttt cattgttgaa ccatttaacc gttccgtgtt ccataaatgt
     6361 atatcctcca aaaaagttct tgcaagtaac cttgcaagaa cattataccc aatttagaaa
     6421 acgctagcaa gctttcgctc ttttattttc caaattattt ttaagactga tatgacggag
     6481 gaaatggtta ttttgctgct tcgaaacgtt tgtttacttc atcccaatta ataacattcc
     6541 agaatgctgc aatataatct ggtcggacat ttttatattt caaataataa gcatgttccc
     6601 aaacgtccaa acctagaatt ggtgtctttc cttccatcaa tggagaatct tgatttgcag
     6661 tagaggtaat agctaatttt ccattttcca ttacaagcca agcccatcca gaaccaaatc
     6721 gtccagcggc tgcttttttg aattcttctt taaaagaaga aaaatcacca aaagcttcat
     6781 taatcgcttc ttttatttct cctgtaggtt cgccaccagc atttggtgcc atgatttccc
     6841 agaaaaatga atggttagca tgtccgccac cattgttacg tacagctgtc ttgatatctg
     6901 ttggaatagc gtccatatca gataataatt cttctattgt tttttcgcct aattctgggt
     6961 atttctcaat tgctgaattt aaattcgtca cataagtatt gtgatgctta tcatgatgca
     7021 gatgcatcgt ttcttcgtca atataaggtt ccaatgcgtc atatgcataa ggtagatctg
     7081 gtaatgtgta agtcataaaa aaattcctcc tcaatgtttt cttaataatg tctacattac
     7141 aaagagtaac aaagagaagg aaattcttca attgttatgc ctagtcgtct ttttcacttt
     7201 gacctacttc ttcttcaaaa acctcagttt ctttaaaaat aaacaacttg ctgaaaatat
     7261 agttcgcaag gataacaata atttgagtga tgattttcgc cacatactca ttgctgttca
     7321 taacattgat caacaatacc attgccccca tgtccaatcc gtaagaaagg atacggtaga
     7381 agaagaactt accgcattca ataagtgcat gtgtaaaatt cggtgatttt gaatggaata
     7441 cccaaagttt gttcgttaca aaagcaaaca atacagaaca aaaccacgaa atagaattgg
     7501 ataaggccat acttaaatca aaatattggc gtgcgagagc aaaactaaca aaatttacaa
     7561 tcgtagccaa accaccaaaa aagagataga ctagtatctc ccaatatcct tttgcttcta
     7621 aatatccttt taactgtcga tactgcttca tgagccaacc taccttatta aaaattctta
     7681 tttatcatac tctatatttc aataactttc atctttattt aaaaaaatta attttttttg
     7741 atcctttgcc tttgtctctg cttggatcgt cacatgtgta ataccatatt ttaattttaa
     7801 taaagaaatt atacgaggat atatcttttc aatctcgctt agtagctgat cttcaaaatc
     7861 aatatgtccg tcgaaaataa ttatcttttc gctatactgc caaatatgga catgatgaac
     7921 atcctttacc ccatcgattg cttcaatttc ttgttccatt ttttcatagt cgatagcagg
     7981 tgcactttgt atcaaaatag cggcagcttt tttgatcacc attatcgctt ctatcaatat
     8041 atatatcgaa atgatcagtg taataactgg atcgatccag tagatatcga aaaaacggat
     8101 caaaattgct ccgataatca cacttaccga agacagtgta tcacttaaca aatgcaaata
     8161 actagatttt atattcaaac tttcatctgc ttcttgtcgt aataataata ctgagaacaa
     8221 attcgcgagc aatccaataa ctgctactgt tagcatcaaa tgactattta tcttttctgg
     8281 tgaagtgaac cgcttgaatg cttcaacggt taaaaacaag gataatatga tcaatatgaa
     8341 tgagttgatg aaagcactca atatttctaa acgctggtag ccatacgtac gttttttatt
     8401 tgcttctttt cgggccattt tttgtgcccc gtaagaaaaa ataattgcca atgtatcact
     8461 aaggttatgg aaagcatctg aaacaagaga caaactccct gacataatcc ctccaataaa
     8521 ttctgataaa gtgatcaccg cattcaaaac cactactcca aatagttttt ttgatgatct
     8581 ctgtggctgt gtaggcacta ttccttcctc cattttattt atattggata gtctttagac
     8641 aagaataaca tttttttgat atttcaccaa tcattcagct gtttccttaa agcacttgta
     8701 tttcacttga tacttcgcta gaattgcaag tgatgacact actagatgag gagtacttat
     8761 gacaacaaaa caattaatta tcagttcctt tatacgattc aaagacctaa aggaggcgag
     8821 aaatgtccca ttttggaaag ccattgtcta tcttttagtt ttgagtataa ttatggcttt
     8881 gccaatctct tttcaagttt ttcaagtctt aaacaacatt caattggatg ggcaaaagat
     8941 tgctactcgc attcctgatt ttacaatcca aaacgggcag cttcaaaccg aagaaaaaga
     9001 aggattcatt taccaaacaa actccattat cttcacattt gatccagagg gaaaacgaac
     9061 agaacaggac atctctactg atttgatggg gaattttgtt agtgtcggga tgttaaaaaa
     9121 caaacttatc atagctcttc ctaatacagg cacgacttct gctttgttga acaataacca
     9181 attagaactt ccctacacca atgaatcttt aaaaaactta acaggtaagc agctccgttc
     9241 ttttttaagt gaagcatcta taccactttg gataaaagtc ctgacattta tattttctat
     9301 ttatcctagt tttctgaatc tgctgatcac tttgctattt accaacattg ctgcttttct
     9361 ctatgcacgc tttcgactaa caaaagctac ttttcttgat tgtttaaaaa cattgatcta
     9421 ttcaatttca ttgcctacta taattgcaac aatcttgatg gtctttcttc cttcttttga
     9481 cactagcgcc ttcattgctt ttgcaggaat ctttattttt gctcaagctg tcaaaggatg
     9541 ggcaaaaata tcgatcaatt aagaaataaa gacaactcgt tatttctact tcaatagacc
     9601 cttttagagg ttgtgacatt tttttgtcac agcccctttt ttatttgaaa aatatttctt
     9661 tctcaaaaaa caagcaaggc gcttcaaagt tcttcttgta tgcgctacac ttagagtaaa
     9721 gaaaggcggg aaattaacta tgtcagaaag aatcatttat gcagatcgtc catttcgtga
     9781 tgaatttatc gaagaaatcc atactatagc gcctggttat atctttaaaa cagaattaca
     9841 accagaggat ctacaaaatg tagagatcag tttgggctgg aactcagact accaagaaaa
     9901 actattagcc tcttctacct tgaaatgggt ccaatctatc tcagctggtg ttgatcagct
     9961 accccttgag actttttcaa agaaacatat tttactttca aatggtagtg gcatccacag
    10021 tgaatcgatt acggagcatg tcttaggaat catccttggg tattctcgtg gtctttttca
    10081 agcacaaaag gcacagagtg acatgaaatg gttaggttca tcggtccatt accaatctat
    10141 ccaagggaaa aaaatactaa tcattggaac tggccatatt ggaaaaatga ttgcaaaaaa
    10201 atgcaaagca ttagacatga actgctatgg aatcaataca tccggtcatc cagcagaagg
    10261 aatggaaaag actttttctt taaatcaact aaaggaagtt cttcctgaag tagatttcgt
    10321 agtcaatatc ttacctctaa cggaggaaac aactgggctc tttgatcagc atatgtttga
    10381 acactttgat ccaaaatctg tattcatcaa tgttggccgt ggtgcttctg ttaagacaca
    10441 agatctggtg caggctttaa ataaccagca actttccttt gcagcattag acgtttttga
    10501 ggaagagcct cttccacaag atcatcctct ttggaaaatg gacaatgtac tgattacttc
    10561 ccacattgca ggtttgacac ctgattttca aaagaaatta atggctattt ttttaaccaa
    10621 tctgaaaagc tactttgcca cccatgagct tcaaaccaat caagtaaaat tgtctgcagg
    10681 atattaatag ctgaaaacaa tattttcaaa agaaaaaa
//
LOCUS       DACGMI010000086        10510 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.089, whole genome shotgun sequence.
ACCESSION   DACGMI010000086 DACGMI010000000
VERSION     DACGMI010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.089"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(220..972)
                     /gene="xth"
                     /locus_tag="IXT46_002639"
     CDS             complement(220..972)
                     /gene="xth"
                     /locus_tag="IXT46_002639"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAQ4948527.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            1085..2005
                     /locus_tag="IXT46_002640"
     CDS             1085..2005
                     /locus_tag="IXT46_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4948528.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2078..3013
                     /gene="murB"
                     /locus_tag="IXT46_002641"
     CDS             2078..3013
                     /gene="murB"
                     /locus_tag="IXT46_002641"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAQ4948529.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            3311..4789
                     /locus_tag="IXT46_002642"
     CDS             3311..4789
                     /locus_tag="IXT46_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4948530.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            5066..7126
                     /locus_tag="IXT46_002643"
     CDS             5066..7126
                     /locus_tag="IXT46_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948531.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            7209..7778
                     /locus_tag="IXT46_002644"
     CDS             7209..7778
                     /locus_tag="IXT46_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4948532.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(7953..8759)
                     /locus_tag="IXT46_002645"
     CDS             complement(7953..8759)
                     /locus_tag="IXT46_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948533.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            8897..10411
                     /locus_tag="IXT46_002646"
     CDS             8897..10411
                     /locus_tag="IXT46_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAQ4948534.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
BASE COUNT         3726 a         1752 c         2070 g         2962 t
ORIGIN      
        1 atctgcggta ataagcccaa ccaaacgaaa aatatgagga actatttttg tttggctgtt
       61 cttattactt gatgcaggac agctttttca caatctctcg ataaacagtg ttcaaaagcc
      121 agtttctcgg tattatgcca aatttatgca aaatgtggaa agccattttc acaaaatttt
      181 tcttaatact cgaaactaaa cgactttttc acaacctctt tatttcaaat ctaattctac
      241 tggacaatga tcactgccca taatgtccgt atggatcttt gcatcagcta gtcctggctc
      301 taaatctttg ctcgtcaaaa agtaatcgat ccgccaacca gcattgtttt tccttgaatt
      361 gaatcggtag ttccaccaag agtagacacc ttcctgggtt ggataaaaat aacggaatgt
      421 atcgataaac ccgttatcca acagtcgaga aagagccgct ctttcttctg gagtgaatcc
      481 agcatttttt tgattcgttt tccagttttt caaatcaatc ttttgatgag cgacatttag
      541 atccccacac acgatgactg gtttttgttt ttttagattt tccaaataat tataaaaggc
      601 ttcttcccat tctaatcggt aatctaaacg ttttaattcg ctttgagaat ttggcgtgta
      661 acaggttaca agaaagaaat cggaatattc caaagtaatc agacggcctt ctgtatcatg
      721 gatatcgata cccattccgt aagtggcatt caatgctggt tttttagcaa aaatcgctgt
      781 gccggaatag ccttttcgtt ccgcgtaatt ccaatattga taataacctg gaagatctaa
      841 atcaatttgt cctgcttgga gtttcgtttc ctgcagacag aaaaaatcgg cgtctaactc
      901 atgaaaaact tctaaaaaat ttttatttac gatggcacga agcccgttta cgttccaaga
      961 gataaatttc aataaaagca cactccttcg aattaatttc cttacctttg cgatactatt
     1021 gtacctcatt ttagtaaaaa atggtgtaat atgaaagtaa ctaaatgatc caggaggaaa
     1081 gtagatgaag attggtgtaa tcggtgtagg gaatatcgca gaaaaagcat atttaccaac
     1141 ttatgcgaaa aaacaaggaa cacttgattt ttattttgca acaagaaata aagaaacaaa
     1201 agaaagaatt caaaaagagt acgggttcca acatctatat gaaacgatcg atgagctttt
     1261 agaagaaaaa atcgaagcat gtatgatcca cgcagcaaca aaagtacatt atgaattagc
     1321 caaaaaatgt ctagaaaatg gtatccatgt ttatattgac aaaccactga gtgtccatct
     1381 aaatgaagtt cgtgaattgc aagaattagc tgataagaac caaataattt tgatgatcgg
     1441 tttcaaccgg cgctttgctc ctatggtaga agaattgaaa cgtatcccag ataagcggtt
     1501 gatccacctg caaaaaaatc gaatagcggc aaaagaaacg acagagttcg tcctttatga
     1561 tttgttttta catcttattg atacagctgt gtatttatta gatgaaccca ttttgagaac
     1621 aaaataccag ataagagaaa caaaggaatt tttggaatat gccattttac aattagaaac
     1681 acaaaatcaa acggctattt taacgatgga tttagcaagt ggcgctaata tagaaaaata
     1741 tcaagtaaca agtaaaaatg gtacttatga agtaaacgat ctgacccagc ttgtcattca
     1801 agatgctgat ggaaaaaaag tgaaagaatt tggcgactgg acaaacacgc tagtcaaacg
     1861 cgggtttgag ccaatggtag aggccttctt ttctcagatc cgtttaggta aatcggaaac
     1921 agaattgctt aaacaaaaag aagttgtaag aagtcatgaa ttatgtgagg aagtgcttaa
     1981 agatcactac cgtcatcaac tttgaacaag actggcaaga ttgtattaag cgtgatagaa
     2041 taatgaggac gtttgagaaa agaaaggaaa atcctcagtg aataaagaag aaatagttga
     2101 aagcttagcc acgattacta tattgtttga tgaaccattg atgaactata cgtttacgaa
     2161 aacaggtgga ccagctgatg tccttgcatt cccgaaaaaa caagaagaag taaagcaaat
     2221 catcgattat tgccgaatcc atgatatacc ttggatggta ttaggaaatg caagcaatct
     2281 gatcgttcaa gatggcggga ttcgcggtgt agtcatcatg ctgactgaaa tgaaacagat
     2341 tcatgtcaaa ggaacgatgg tcattgcgga agcaggtgcc tcactgattg atacgactta
     2401 tgcagctttg gcagaatcat tgactggatt tgaatttgct tgcggcatcc cgggaagtgt
     2461 cggtggagcg gtttatatga atgcaggtgc gtatggcgga gagatcaaag atgtttttgc
     2521 tgaagtggat cttttgcttg aagatggaac attgaaaact ttgacaaaag acgaaatggt
     2581 attttcttat cgtcacagta aagtccaaga attacgtgct atcgtattgg aagctcgatt
     2641 cagtttgcaa acaggggatt atgaagcaat caaagcaaga atggatgagt tgaccgaatt
     2701 gcgtcaatca aaacagccat tagaataccc ttcatgcgga agtgtcttta agcgcccagt
     2761 aggacactat acaggtcagc tgatccaaca agcaggattg caaggcctga aatggggcgg
     2821 tgcacaagtc tctgaaaaac atgctggatt catcgtcaat atcgatcatg cgacagcgac
     2881 agattatatt gaattgattg cgcacatcca agaagtaatc aaagaaaaat ttgatgtgtc
     2941 tttagaaaca gaagtgcgga tcattggaga aaaacaagca atatcagaaa caagcagaag
     3001 tttagccaat taataagtaa tggaacttaa aataagtaaa agagcaggac ggtggccgtc
     3061 ctgctctttt ttgtggttgt ttacgcaaat ggcgcaaatc ttgtacattt taacacaata
     3121 aaacaaaaaa tatagaatat ttcctcataa atttttccat tttttgcaat attctcaaaa
     3181 aaaagataaa aaatgagaat aactgatgaa aaaacaagca taatccatca taaaatcagt
     3241 ataggtgaaa agatgaactt tcatctgcat atcaagtaat tggtatgagg cattttttga
     3301 ggtgtaggat atgaagttgg attaccttat agaagaggaa gatagagaaa aactgctgct
     3361 agctagatat ttagaatttg agaaaaagaa ttatgtagtg ctgcctaagt tatatgaaac
     3421 attaggtttg tctaaattta aaacaagaaa ttatatcata gaattaaata aagaatttac
     3481 tgaattcaaa acaaagccag agatccaaat ttcagaagaa gcagagatcc atgtcgaacg
     3541 tctgaatttg acggatatca aaaatttaag aagaatctac tttcaacgat caaaaattgc
     3601 tcgactgtta acggagatcg tggattcaaa agtaacgatc gaaaaatttg cagagaatca
     3661 ttttttaagc atatcaagag cctatgtaaa aagaagagaa ttagtctctt ttcttgaaca
     3721 gcatcaaata aagttaaaga aaaacatatt agttggggaa gaaataaaca tacggaacgt
     3781 attatttggg gtatatttcg gggtctttaa tggtttttct atgccattta gagaaagcgt
     3841 catgaatgaa gcaaagagta tcgtgcaata ttttgaatat ctgttcaatt taaaactgtc
     3901 tgcaacaaaa cgaatcaaat tcaatttgct aaccactatt agtttgttga gggcctatgg
     3961 gaatcaacca atcggaaaac gtttcttttc agatgaatac tttaagagct cagaaggaat
     4021 gaagatcatc aaggatttat cacatatttc ttttcttcat atccctaaag agcagatcat
     4081 tgatgagatt tcttatatca tgttgttttt gatcacggaa gaagaatttg aattagatgg
     4141 cgcatttgga cttgcggaag ctcattttca tgatatccac atgattagtc aaaaaatgtc
     4201 agtggaattg attgatcaat taccattttc gattgaaatc tctgaagaag aaagactata
     4261 tatacgaaaa gaacttcgta tgggtatgat gcatgtcaat cgaaaaaatt ggatattcga
     4321 ctttgagatg actagcttta cgtctaaaaa gcagctacag tttttcttcg agacgtatcc
     4381 aatattcagt acagcaatcc aaaaggtcat acaagagaat aaacgctatt tcttgggaaa
     4441 agatgaacgt ttcatgattc gcttatttta tgattatctc tttttattgg tcggtatttg
     4501 tccggtatca tattttgaag caccgattca tgtctgtatt gatttttcgc aaggatctgc
     4561 ttataccgat tacattattt ctcaagtgaa aggatttaaa aattacaata ttgtgattga
     4621 gagtcgaatc acttctcgta cgaatattta tttatctgat tgtttacttg aaaaatttaa
     4681 taaagaacag ataatttgga aaaatccacc gactccagat gactgggaat attttggaaa
     4741 taccatcatc agagaaaaaa atagacattt aactgaaaaa atcagctagt atttatggat
     4801 ggcagctttg tctcacatat ttattagctg atttatgttt ttttcaaaga aaaggtaact
     4861 agatataact agatataact agatatatta cttaacaaaa ttaaaaagta cataagttat
     4921 tattccgatt ttcttgaaac aataaaaaat caaaaaaaat actctcctaa tagtccatct
     4981 tcttttgatt ttatttatat aatgaaatca tcttatgaaa attactactt catgtttaga
     5041 caagagtagg gaggactaag aataaatgtg ttcaaaaaga cgttcaaaac aactaaataa
     5101 acacgcttgt cgtttagata aggaacggtc gtgttctgaa aaacactacg ttaagtttat
     5161 gatgcgcacg atgctgatca gtttatctgt aggtgtctat atgcatgtac ccgttcaggc
     5221 aacgacacaa accatcaagg tcgtacgtac ctctgtttct gagaccactg attcccctat
     5281 cactattact catactttca ctgatgcaaa tggaaaacag ctacttcctg cattgacttc
     5341 ctataataaa gtcagttatc ctccaacgat aaaccactac tggttaattc ctaacaaaac
     5401 attatggaca tcggaaaccg gaagcagtgt gccgctttct atcttttccg atatgactga
     5461 tcctacaaaa ggtgatcagt taaaacagat cactgatatt ttgaatcatg ctttgacaga
     5521 tataaaggac ggtggaagcg cacaagtttc ttatgtatat gaaaaagatt attcacagtt
     5581 tgaaagaaag aaaatcgatg ttctggcagg gacaaaagtt tcgatatctg atctggtaga
     5641 aaggctgaag aacgcagatg gaacacaagg agatatgtcc aaagtaattt caaacaatgg
     5701 gaatatcgtg gatacgacta atacaggaac atctactatt tccttgtcct attttgatcc
     5761 aattgcttta aaaacaatga ctgcatctgc tgtgatccat gttcgtgctg atcaaacagc
     5821 tatcaaagga aaagatcttc acttaagaac aggagagagt tacgccccta aagatcttgt
     5881 tgaatatgta acaaaaagcg atggaacttc aggaaataaa gaagaaatca aaatgaacgg
     5941 gacagtagat actacaactc cgggagaata tcccgttgta ttaacttata tagactcgaa
     6001 aacatcaaat gtggcagaaa caacagctgt agtttatgta gaagcatctg ctgcttcatc
     6061 gactgtcatc actcatttta tagatagtca aacaaataaa gaacttcaag cagaaacaca
     6121 tatgagtagt gtaaatcgta ttcctgattt gcgcctacct gctgaatttt ctgatcgagt
     6181 gccaaatata gatttatcga cttatgaaca aaatgggaaa gtcacttcta tttctgattg
     6241 gatgcaagca aacggattag acagaaaaag tcactggtcg gagatccttg aagtacttca
     6301 ctcagaactg atgaataata ggaagcaatc aggaggggaa attaccttta cttatgttta
     6361 tataccagac aatcgttcat tagaaggtca tgatcttatt gttcatccaa acgaaaaaat
     6421 aaacaaagaa gagttgatcc aatcagcaac aaattcctta ggtaaacccg taccgttaaa
     6481 ggatgtatcg gttacaatca atgaagtacc attggaggat ggttatttga ccaaacaaac
     6541 aggtgatttt acgattatgt atagttatca tgacccgtat tcactccaag aactccatgc
     6601 tcagtcacta ttacatgttt taccattaaa caaacagata gatcaaaaag aacaaaaaag
     6661 acaagaagaa agcttgtcag aaaaaaaaca acaaatggct catgcagttt ctccaacagg
     6721 gaaagtaaaa caaacaagaa gcctagagtt agcaagaata tctagaaaaa tctcagaatc
     6781 taataaaacg ataaggcaag aagctcattt ggccccacaa gtttctggat tggaaaatga
     6841 aattttagag cctaaaataa aacaacaatc agaaaaagaa tttgttgcta aacagtcgga
     6901 agatcagaag gaatcagatg accagaagga aacgaagaaa aaacgcttgt caactattga
     6961 ttccaccgat gagcatctgc agccgcaagt accacttcct agtccgggaa cacccgcacc
     7021 tggtggaggt attccttctt ctgctttagg agatttcatg cgaggtatgg caggaacatg
     7081 ggtatacgct aatcgaaatg aatttgacgc agatgactgg ttctgattta tatctctatc
     7141 tgttatagtc aaataagtag ctgagtcata tgttatttgg cataatggag acgaggaggg
     7201 atagaaaaat gttagataaa acgttacctt acgcagaaat ctggatgaca agaccacttc
     7261 aacaaaatgt tccaatcacg cctttagcgg aaggttttga atttcgattt tatcaaaaag
     7321 aagatgaatc tgcttgggcg gagattgaga cttccgttgg ggaatttcaa acgacagatg
     7381 aagcacttga gtattttcaa caaaactttg ctccttatcc tgaagaactt gaaagaagga
     7441 tgttttttgt agagacaaaa aaaggagaaa aagtagcaac ctgtaccgct tggcgaaaaa
     7501 aatcaagaga gcaagtgtat ccggtttttc attggttagc agtgaaacca gattaccaag
     7561 gaaaagggct cgcaaaagca ttgactgcca gagtcttgca agaatttcct accctccata
     7621 cggacggacc aatctatctt cacacacaga catggagcca tcaggcgatt gctctttata
     7681 aaaaaatggg ttttactttt attgctgaaa atctagacgg cacacctaat ccagattatg
     7741 aaaaagttat gcaggtttta agtaaattag ataaataacg aaatggtgaa ataagtcctc
     7801 agtattggga taaaaaacga aatagtcatt cctcatatct tacttttttg agttaatact
     7861 atcggataac taatggcatg ccatacattc aaaaaagaag gggcagtgac aaaagtattg
     7921 tcactgcccc ttctcttgtt ttttagcatg ttttatcgtt tgattttttt aggaataaaa
     7981 ttcttgatga acgtaaattt ttggtaatcg tttcgactat agaggtaacc aaatacactg
     8041 aaaacaactg ctccaataaa attaacaaat aaatccttca tagtatccat gattcccacg
     8101 tctaagtaac cattttggat gattgtttta tctgttttac catctgcatt ttgactttca
     8161 atgattgtcc gagtgatatc tggaacatga tagacagtgt ttccgtcttt acttaactcc
     8221 acactattga tttgctggat gatcgtatct ttttgcatat cgaattgcag taatttatct
     8281 gctgaaaatt ccacaaactc ccacataaca ccaactgtca tcgaaaaaca gaaggaaaca
     8341 actgctagta ataaaggagt caagttcatg gtttttgtat ttttattgag caaataaaca
     8401 agggaaaagc cgacaccccc agctaaaaat ccgctgaatg catgtagaaa agtatcccac
     8461 attgaaaaat agccataaaa atcacttaac tctcctaaaa ctgttgaact aaaaataaaa
     8521 gataacaaaa tgatttctag catatttgga atctgtatct ttaatatctt ttccagaaaa
     8581 taagggattt caaataaaat taatgtcagt aataaaagca ttgtatttcc ccagtgttgg
     8641 ttccagacct gatccactag cataataacg acgatgatac gtaataaaat atagattccg
     8701 tttgtgattc tacctgcagt ttttgtactg ttcgtaaaaa aggttttcaa atgattcata
     8761 aaataactcc ttcatgtata tccttaatta tactaagaag cgtgtgttta ccaaagctat
     8821 atgacttaaa gaaaaacaga gttgatattg tgaaaaaaat cacttaatat agtataagga
     8881 gaaaaggggg atacaaatga aaaaattagt tgctggttta ttaacagccg ttgcacttct
     8941 tgctatgagc gcatgcggcg cagatcagaa aaatacagcg cagacaagtt ctagtacgaa
     9001 ggaatctgcc gaagtatcat caggcgcttc tgaacaagta tatacagatc caaaagaaat
     9061 gaaagaatct tatgatgtcg tgattattgg agctggtggt gcagggatgg cagcagctat
     9121 cgaagcaaaa gatgctgggt tgaatccagt aattttggaa aagatgcctg ttgccggagg
     9181 aaacacatct aaatcatcaa gcggtatgaa tgcttcagaa acaaaatttc aaaaagaaga
     9241 aggaatcaaa gactcgaatg atgccttcta tgaagaaacg ctaaaaggtg gtggaggaac
     9301 gaatgataaa gaaatgcttc gatactttgt cgatcactct gctgatgcgg tcgattggct
     9361 agatcaaaac ggtatcaaac tggacaactt aacgatcact ggagggatga gtgaaaagag
     9421 gacacatcgt ccgtctgatg gctcggctat tggtggatac ttagtggagg ggttattgaa
     9481 taacgtccat gagcgggaaa tccctatttt tgtcaacgca gatgtgacag acattaagaa
     9541 aaatggggaa acggtcaatg aagtgactgt acatgttcaa ggagaagaac caaaagaggt
     9601 caccggaaaa gcaatcgtag ttaccacagg cggttttggt gccagcaaag aatttattga
     9661 aaaatatcgt cccgatttag ctgattatat tacgacaaat caagaaggat caactggaga
     9721 tggtatcacc atgattgaaa aattaggtgg acaaaccgtt gatatggata aaatacaaat
     9781 tcatccaact gtgcagcagg atgagggggt cttgattggt gaggttgttc gcggagaagg
     9841 agcaatcttg gtcgatcaag aggggaaaag atttgtcaat gaaatggata caagggataa
     9901 agtatctgca gcaattacag cattgcctga aaaatcagct tatttgattt ttgaccaagg
     9961 cgtgcgtgat cgtgccacag ctattgaatt ttatgaccaa aaaggatatg tcacaactgg
    10021 aaagacaatg gaagaattag cagaaaaaat cgatttacca aaagaaacac tagcaaaaac
    10081 agttgatgga tggaatacgg atgttgcgga gaaaaaagat gctcaattca accgtgccac
    10141 agccatggaa catgacttat cgtctccgaa ttattatgcg atcaaaatcg caccaggaat
    10201 ccattacacg atgggcggtg tgaaaatcaa tacgaacact gaagtattag ataaagaaaa
    10261 ccagccaatt agggggttat atgctgctgg tgaagtcaca ggtggcttac atggaaacaa
    10321 ccggatcggt ggaaattcag ttgcggagat cattattttt gggcgacaag cgggcataca
    10381 agcagctcga tttgcttcgg aaaatgaatg aaatagaacg taaataaaaa gaggttgtga
    10441 aatcagcgtt ttgagctaat accgagggtc agctgattga acactgttta gtgaagaggt
    10501 tgtgaaaaag
//
LOCUS       DACGMI010000087         9882 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.090, whole genome shotgun sequence.
ACCESSION   DACGMI010000087 DACGMI010000000
VERSION     DACGMI010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.090"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..407
                     /locus_tag="IXT46_002647"
     CDS             <1..407
                     /locus_tag="IXT46_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948535.1"
                     /translation="QEKLERMNQLTTVMRTYVQTIKLVSLTTETDLTEQIVQKRQLLD
                     KNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDLQTRNR
                     QLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            570..2594
                     /locus_tag="IXT46_002648"
     CDS             570..2594
                     /locus_tag="IXT46_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAQ4948536.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASRLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            2594..3799
                     /locus_tag="IXT46_002649"
     CDS             2594..3799
                     /locus_tag="IXT46_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAQ4948537.1"
                     /translation="MENQDESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNDNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFTDDGTWIDP
                     LPFLNSSKK"
     gene            3815..4459
                     /locus_tag="IXT46_002650"
     CDS             3815..4459
                     /locus_tag="IXT46_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948538.1"
                     /translation="MENKTLKIVLTAALSISLIGNIALFWQLKEEQATNTYKIEEVAK
                     NASEKLKKNFSEAQAKIDKLNQTINEKNQEIDQLKQQDGIKAKEEVTDAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAETS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            4470..5276
                     /locus_tag="IXT46_002651"
     CDS             4470..5276
                     /locus_tag="IXT46_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948539.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFTILGFLILASPIYTHKKVNI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQGLLKELANLDYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIVPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDDNYEQHAINYKVKGYKKEQKAAQKQIESLQATIDLNEELVNKLKDQLP
                     YQVADDQENTENKINDYQQEIETSKTQMKDQEEIIQKIQEKIDRMTKENI"
     gene            5299..5529
                     /locus_tag="IXT46_002652"
     CDS             5299..5529
                     /locus_tag="IXT46_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948540.1"
                     /translation="MKGANLVGKDIFAEQKVLIKAYLKVVKAKEICQEVNLSNTTISE
                     LKNGRKSLDTLKIRSFEALYLAAKKYFTAERK"
     gene            5647..6606
                     /locus_tag="IXT46_002653"
     CDS             5647..6606
                     /locus_tag="IXT46_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4948541.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERLVS
                     CGMRTLYRLFSKGIFEIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQCPLNENSNGILRRNGLPKSMDFRE
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            7100..7387
                     /locus_tag="IXT46_002654"
     CDS             7100..7387
                     /locus_tag="IXT46_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948542.1"
                     /translation="MEIKEIKVRGINKKYVQEIDHRCVELTEQTGQKWSRNDYLKLLI
                     ENDFERPLMDYKKDQFDRLLEKFTDVQLHNTKVLEAYTNEVKNLIEILIAH"
     gene            7405..7827
                     /locus_tag="IXT46_002655"
     CDS             7405..7827
                     /locus_tag="IXT46_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948543.1"
                     /translation="MVKAIEKHITFYEAHDEVLKHIMETQPTVKNYSEAIRFLCMNYD
                     PEIEKNNNMTNAKLNAMGKEISILIEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKSINESVHARVDPFDPTKFLKR"
     gene            7847..9439
                     /locus_tag="IXT46_002656"
     CDS             7847..9439
                     /locus_tag="IXT46_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948544.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMGNGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQNSQIKPLIESMD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQIEQERQ"
     gene            9695..>9882
                     /locus_tag="IXT46_002657"
     CDS             9695..>9882
                     /locus_tag="IXT46_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948545.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT         3708 a         1573 c         2030 g         2571 t
ORIGIN      
        1 aacaagagaa actagaacga atgaatcagt tgaccaccgt catgcgtacg tatgtgcaaa
       61 caattaagtt agttagtttg accacagaga cggatctaac ggaacaaatc gtacaaaagc
      121 ggcaattatt agataagaat cgtatggaac aatccttagg aagaaatcta cagcgattaa
      181 gaaaatatga aaagaaatta gtagaggaaa tccaggaatt gaaacgagca gaacaagaac
      241 gtcctgactt aagcttcttt ttcgtcattg aaggaaagac aatcaaggat ttacaaacca
      301 gaaatcgtca gttaatgcga tctagtggca ttttagggtt aaaaccactc tacaaaaaag
      361 aattgatcaa gattctttat cgaatgaaca atatgaatga tgagtaggaa tggagaagag
      421 agaatgaaat atccgttgat atggttagaa aatgatgttc cgaaggaaga gatcactaga
      481 aaattttctc acactttaag cctgggtaag ttgggaaaag ggcaatcttt taaccaagta
      541 aagaatcaaa caagaagagg tgactgtaca tgttagaagc gattaaaaca gctttttcac
      601 cacaaaatga tcaaaaagta cttgatccat taaagcaact aggaaatcgg gaaatagaaa
      661 ttttaaaatc caaagggtat gatttagatt ttttaaaaca agtgatgcca caaggtggat
      721 taaatttcga tgaagagtat gtgacctatg gaaatggtta ttcacgatgt gtgacagtct
      781 atcactatac aaaaaatcct actctttttt ggttggccaa tctcatgaac aatcctcata
      841 cagtggccac actagatgtt agcacagatg aaaagcaaaa agtgattgat caaatcaacc
      901 gcgcattaga tgaattaaat gatcgatcag ataatgaacg aaaagcgact gaccgaaata
      961 aaagtgcgga agaatacctg gaactagcgg aatatgcccg aaaattgact tctaatgggg
     1021 aaatttctaa acaagtcaaa gtgagagtac atgtttacgg aaatacgata caagaagtgg
     1081 atgaacgggc gcaggaactg atcgaaaatc taaaagggat ggattatcgt gcggtgactt
     1141 atctgcataa aaccaaacga gattggcaat cgatgtttac catgttcgat gaacaagctg
     1201 aatggttcgg aaatatcaaa gggcaatcac taccatcgtt aaacattggc ggaggtttcc
     1261 cgttccacca ccaaacgcta aaagatccag gaggtacaca atatggggaa accatgacag
     1321 gcggcccatt tgtctggaat gcgacgtata aaaatagtgt acggttgtct actaatacct
     1381 tgcttctagg aatgatggga gctggtaaat cgaccgttct taaaatgatc gcggaagccc
     1441 atttagctgc aggagacttt atttggggct ttgaaaaggg aaaagacttt attcctttct
     1501 taaaggaata taacggtatt atggtgcgtt tagacggatc tgacgggatg atcaatcctt
     1561 tagagatatt tgccacacgg acgtatgatg aagcatccag gttatatgac gatggatcag
     1621 tcaaagattt gaagatcaat gaagcagcgt cctatcaaac gcacttagac aaagtagtct
     1681 atcaggtaca gttagtgagt cctcagctaa aaggaacgat gaaagcagaa tttaagacct
     1741 acttaaatcg tttttatgaa gagtatggaa cagtaccacg tggctttact tcctcaaatt
     1801 cgcgttcaaa tactgatacg caagtcacag gtaaagatcc agaagcttat ccgacgttca
     1861 aagaattttt agacttttta ggacaactgg aattaccagg tgcttcccaa gagaaaaaga
     1921 atcgaaaaga agaaatggaa tccatcgtag aatccttatg tgagacgtat ggcatgattt
     1981 ttgatggtca cagtacgatt cgacaccttg accaacaaca gttggtcttt tttgacattg
     2041 actctattac aggtttagat cgaggggtgc aacaatgtca aatgtacatg gctatgacgt
     2101 tgatttggaa tcaggcattg atccagggaa gaagacaacg acgtttaatt aaagaaaaac
     2161 aaatggaaga acaagacttc aaacgcttct tggcgatgat tgatgagtgc cataatgcga
     2221 ttaatccaga ttttattgaa acggtaaatt atgtcacaaa ctttcaacga gaaatgcgta
     2281 aagtagaagc aatgactgtt ttagctacac aatccccaca agaaatggtg ccagaaaata
     2341 tgtcttctga taacttctcg aaactgaaga aagtctttga attttcttct acgaagatct
     2401 ttatgcgtat ggatgaatct attttacgtc atatagaagg actagtgggt aaatcaatga
     2461 cgaactcaga attagaatcc attcctcaac aaaatcaagg agacgctgtg atcaactttg
     2521 gatcaaaaga aaccattcgc gttcatttta gtccgaacaa acgtcaatta aaattgtttg
     2581 atggaggaaa ataatggaaa atcaagatga aagtttaatc aagcagtatg ttaagcgtcg
     2641 cgcaaagcgg cgcttatttt tgtggttgtt tggtacttct gcaggtttga ttactatttt
     2701 gatcactgtg tttgttaccc tatttctaat acttgcggcg ggttcgattg ataattcgga
     2761 ttcagattca agcagtggtg gcgaagcttt tacaggagaa tattcggaag gcttaccgat
     2821 ttataaagaa atcaaaggaa gaggcccttt ttctgatgag attgcgcaat atgccgtagg
     2881 tgcagcagtg aaatataaat tattaccaag tgtgattctt tcgcaatacg gttatgaatc
     2941 agcgtttggt acgtcggcgt ccgcaagaaa tgatctcaac tattttggga ttacttggtt
     3001 tgatggttgt ctgtttccta aaggaactgc acgaggaatt ggtggcattg aaggtggctg
     3061 gtacatgaag tttcccaact caaaagctgc attctcctat tacggcttta tggtagccac
     3121 acaatcaaat tttaatgcat gtgtaggaaa taaaagccct ggcgcaagct tattgatctt
     3181 aggacgaggt ggttatgccg ctgcaggaat tactgaagat agtccgtatt atacaggttg
     3241 tatgtcgatt attacctcaa ataaattaac agaatatgat gaatttgcga tcaaacattg
     3301 gggagaaggc ggaaatgaca acggtacgat tactggtgaa tggacgaatc ctttccctgg
     3361 cagcagttta gataaaagtt ccttcagcgg tggtcaatta tttggaacga atccaggcgg
     3421 tgaattccgt ccgaatggtt tccatgatgg attagacttt ggttcagttg atcatccagg
     3481 aagtgagatt catgcggttc atggaggaaa agtcgtgtac gttggaaatc ctggtatttc
     3541 aggtttgggc gcgtgtgtga tcgtgattaa ttacgacggc ttgaatatgg tatatcaaga
     3601 atttgcaaat agtacaggaa attcccgtgt gaaagtggga gatcaagtga aagttggtca
     3661 agtaatcggg atacgagata cagcacactt gcatttaggc ttcactcgaa tggattggcg
     3721 tcaagcacaa ggacacgcat tcacagatga tggtacatgg atcgatccat taccattttt
     3781 gaatagcagc aaaaaataga tcaggagaaa aaatatggaa aataaaacgt taaaaatcgt
     3841 cttaacagct gcactcagca ttagcttaat tggcaatatc gcgctctttt ggcagctgaa
     3901 agaggaacaa gcgacaaata cctataaaat tgaagaagtg gctaaaaacg cgtctgagaa
     3961 gctcaaaaaa aatttctctg aggcacaggc gaagatcgac aagttaaatc aaaccatcaa
     4021 tgagaaaaac caagaaatcg atcagctgaa gcaacaagac ggtataaaag caaaagaaga
     4081 agtcacagat gcccaaagaa agacggcaga agagttcggt caattggcca ttgataaatc
     4141 actaagcaga aatgaattaa cggaaaaact aaaagatgtc gcaacccaag aagtgatcga
     4201 caaattaagt cctgcagatg atgatcacca acatgatgat tatggaagtt actcctttac
     4261 attaggtgac gtgcaaactt acgctgaaac aagcagtgta aaagaggaac aaaattttgt
     4321 cgtatttgtt gattatacaa tcggcaatcc tcaattcaaa gatgtcaaac cgcaaaaaat
     4381 aaaaggtgga ttaactgtca ctgaaaaaca agtagatggt caatggaaag tcacagactt
     4441 tagttatttc actcgttagg aggaagaaaa tgagtaagaa aaaaggagca agacaacgtt
     4501 ttaaaaaacg gaaaagttat cttagatggc tgggaatctt tacgattctc ggctttttga
     4561 ttcttgctag tccgatttat acgcataaga aggtaaacat accagatgag gtaagcacga
     4621 acgctttttt aaacacgaaa gaactgacaa tggtatcaaa agaaaaagga gcgaatcagc
     4681 aattagtttt tgaatttgcg attgacgatg aggatcaagg cttattaaaa gaactggcta
     4741 atcttgatta tcgcgtagaa gtaaagacag ctaaaggtga ttatcaagca ataaaagcca
     4801 aagtgatcaa ggtgtctgat gattattttg tagtgaaatt agcacatgta ccagaagaat
     4861 atatcgccat gcgtttaacc attgttcctg aaaaaattga tccaaaagtg gatatgcaag
     4921 aaccacaaga tctgatttat tacgttcacg aagataaggt taaggatcaa gtgaaagatg
     4981 ataattatga acaacatgcg atcaattaca aagtgaaagg atacaagaaa gaacaaaaag
     5041 cagcacaaaa acagattgaa tccttgcaag caaccattga tttgaatgaa gaattagtga
     5101 ataaactaaa agaccaattg ccttatcaag tcgcagatga tcaggaaaat actgaaaata
     5161 agattaatga ttaccagcaa gaaattgaaa catcgaaaac gcaaatgaaa gatcaagaag
     5221 agatcattca aaaaattcaa gaaaaaattg atcgtatgac aaaagaaaat atttagtaga
     5281 acaggtggag tgaaagaaat gaagggagcg aacttggtcg gcaaagatat tttcgctgag
     5341 cagaaagtat tgattaaagc ctatctcaaa gttgtaaaag ctaaagaaat atgtcaagaa
     5401 gtgaatttat ctaacacaac aatatctgag ttgaagaatg gtagaaagag tttagatacc
     5461 ttaaaaatca gatcatttga agctttgtat ttagctgcta aaaaatattt tacggctgaa
     5521 agaaaataaa aacaggagga ttttatgtga cgcgaattgt aaaattaagt tagaaaaata
     5581 aaaaggcatt tatggtacac tcaaattgta tttccgacga aagaaaacaa aggagtgtaa
     5641 ccataaatga cctacaaaca tcttaccata gacgaactga caatgataga atcatattat
     5701 cttcaacata ataagccggt tgaaatcgct aaccgaatgg gacgtgctat acaaactatt
     5761 tataatgtag tcaataagtt caagcaaggc aagactgctc ttgattattg gcaccagtat
     5821 aaagaaaata agaaaaaatg tggtagaaaa gtcattcaat tacctgctca tgaagtagat
     5881 tacattaaag agaaagtcac tcttggttgg acgcctgacg tcattatcgg gcgaaaagaa
     5941 aggcttgttt catgcggtat gagaacactt tatcgtttat tttctaaagg aatatttgag
     6001 attgacacac taccgatgaa aggtaaaaga aaacccaatg gccatcagga aaaacgggga
     6061 aaacaacagt atcagcgctc aatccatgat cgacctgata attatcctga tttcaattct
     6121 gagtttggtc accttgaagg tgatacgatc gttggcattc atcataaaag tgccgtcatt
     6181 actttagttg aaagattatc taaagtcatt atcacgatta aacccaacgg ccgtaaggca
     6241 ttagatattg aaactgccct taatcaatgg ttttctcgct tccctaaaaa cttctttaaa
     6301 tctattacgt ttgactgtgg aaaagaattt tctaactgga aagccattag taaccaacat
     6361 gatattgata tatattttgc ggaccctgga acaccttctc aatgcccatt aaacgagaat
     6421 tctaacggga ttctgcgtcg taatggactg ccgaaatcaa tggattttag agaagtgaat
     6481 cagacattta tttccagtgt cagcaatcaa cgtaatcata ttccaagaaa atcattgaat
     6541 tacagaacac caatcgaaat atttttgagc tatgtacaag aagcatttta ttctagctta
     6601 atttgacaaa tcatatgaaa aaagtatata aaaaatgttt atggatcagc tatatcaccc
     6661 taggtatagc tgttaaagag atgggagaaa acattaacca cgattctaac acaaacatca
     6721 agcacataaa acatttaaca ctcctccttt ctggctgaag atttcaacca aacaggaaga
     6781 cagcgtatca attatagcat acactttttc ttaaattcat ttttcatatg acaaaatatt
     6841 tccttctaat cgacaaagtt agaaggattt tttattgtct aaatacacaa ataaccttaa
     6901 tttttaaaga gcataaggaa acgtgggaac actttttaaa aaaagtgttc caataggctg
     6961 tgcctattac gtttctctaa aacaaaagtg ggtacaaaat attcgattta tggatagtgt
     7021 atggatagta aaacagctat acatggatag catatggata gactccatag actatccata
     7081 cttttttcgg agggtgaaaa tggaaattaa agagattaaa gtaagaggta ttaataaaaa
     7141 atatgttcaa gaaattgatc atagatgcgt agaattaaca gaacaaactg gtcaaaaatg
     7201 gagtcgaaat gattatctaa aactattgat tgaaaacgac tttgaacgtc ctttaatgga
     7261 ctacaagaaa gatcaatttg atcgtttatt ggaaaaattt acagatgttc agctgcataa
     7321 tacaaaagtt ttggaagcat acacgaacga ggtcaagaac ttaattgaaa tattaatcgc
     7381 acattaggaa ggagataatg ttctatggtt aaagcgatag aaaagcatat tacattttat
     7441 gaagcgcacg atgaagtttt aaaacatatt atggaaactc agcctacggt aaaaaactat
     7501 tctgaagcca ttcgattttt atgtatgaat tacgatccag aaattgaaaa aaataataat
     7561 atgacgaacg caaagttgaa cgcaatggga aaggaaattt ctattttaat agaaatggtt
     7621 tcagagtttg cggatcttca tttgaaagat acaggaatat taattggtac aaattcaact
     7681 gtctatcaag aagcaaaaga gcgtgtggaa gggaaaataa aagcgaatca aacgaagaag
     7741 tattctccta aaatcaagaa atcaataaat gaatctgttc atgccagagt agacccgttt
     7801 gatccaacaa agtttttaaa aagataaaaa gtagaagggg aatatgatga ataaatcgcc
     7861 tgcagtcatt ctcacttgtc aatttacctt gcccaataaa aaatcttttt caacatacat
     7921 tgattatatg acaagagaaa aagcgctgga agaaatggaa cgacgtacgc ctgaagaaga
     7981 acaggaactg caacgaatca agaatgcttt agaggatttt tatattcctg aaggagaaac
     8041 tttttcggag agtaagacgg ataaagaatt cagcgaaacg tcgaatgaag ctcaatcttt
     8101 gatgggaaat ggaatcaact ttgacaagtt agaggaacaa gattttacca aatatctttc
     8161 ttatatgacc cgtcactatg cgttagaaca aaagaaagaa ctgacgcaaa gtgaacaaaa
     8221 agaataccaa cgcttgaacc aagcaataaa aaaatatcaa acagagccac acaaaaaagc
     8281 ttcaggaaac cttcctggag ttttttctat ggcttcagac gaagtgaaag gaagtgatct
     8341 gaaggagatt aagcaaatct tccaaagagg acaacaaaaa ggctcaatca tttatcaaga
     8401 tgttgtctct catgataatt cgtatcttga aaaaatagga ttgtacgatc ccaaaacaga
     8461 tactttagat gaagaaggat taaaagcagc tggaagaaaa atgatggaga cattattcga
     8521 gaaagagcaa ctgaacgaaa caggctactg gatggcaacg attcaccgta ataccaaaca
     8581 tatccatatt cattttgcag ttgttgaaaa agaaaatacg cgtaaacctt acacggaggt
     8641 tgaaaatggt gtgagttata tcgtaccgaa aggtaagaga agacaagcaa cattagacgc
     8701 aatgaagacc aattatgtac atgagttaga acgtttttct tatgaaaagg atcgaatgat
     8761 tggtatggag aaacgaaatt tattgacgcg gaaaagtgat ttgcgtaaca ccttaacaaa
     8821 agtggtaaaa gagccagcgc gttacgatcg acacgcaatg aacttattaa atgaagtata
     8881 taaaacccta cctgacaaac gttcggaatg gcattatggg gatgaaaaac gaaccaaact
     8941 ttcaccatac acaagagaga aactcgatga gttaaccaaa tatgttttaa caaaagaacc
     9001 tgaatatcaa gaatatatac agatttcaaa agcattgaaa gaagaagcaa aaagtcttta
     9061 tggggaaagc aaaagagaat caaaggatgc agaaaaaaat gctctctttg atttgaaaaa
     9121 gcgcacagga aatgccattc taacagaact gaagaaacag aatagtcaaa taaaaccttt
     9181 aatagaaagt atggatcaga tgcaatctat ttacaatgaa cgatcctttc gaacgcttaa
     9241 acagttacca acgaatgaat acaaatatag ttacgaagaa ttcatgaagc gcaggaaaca
     9301 attccaacaa agagttgtca cgcaacggag tttgcgtcaa ttaaatcgaa cgattaatgc
     9361 ccatgaagaa aaataccacg caagtaaagc ctacgaagag caacaacgaa gaatccaaat
     9421 agaacaagaa agacagtaaa gacagtaaag ttagcgcctt attatactac ttgggaaatg
     9481 aatgaagagg ggatcaataa cttcccgtgt aaaagcattg aagagtctat ttcactcaca
     9541 gaatgttagt tgttaagtga ataaaagaag taaaagagtc ctgaacgtaa ttgtccagga
     9601 ctcttttttt caatgaattg ttttccgcca attcaatgag tggtgcgatt tgcgactaca
     9661 ttatatcaaa agaaagagaa gggaggaaga agaaatggct tattcaacga ttggagttgt
     9721 tgttgaaaaa agcagagaca atctcgtttt tgtgacagaa attcaaacag gcagagcttt
     9781 tgtcgtcaca gacaaagcgg caaaagcgta tcaaaatggc gatattttaa cgttaaatct
     9841 gactacgaag acgttcgtcg atgcggcaga agattatcca tt
//
LOCUS       DACGMI010000088         9635 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.091, whole genome shotgun sequence.
ACCESSION   DACGMI010000088 DACGMI010000000
VERSION     DACGMI010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.091"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..323
                     /locus_tag="IXT46_002658"
     CDS             <1..323
                     /locus_tag="IXT46_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948546.1"
                     /translation="KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVL
                     SAGGQLMGDGKSELVSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNS
                     VELE"
     gene            337..1026
                     /locus_tag="IXT46_002659"
     CDS             337..1026
                     /locus_tag="IXT46_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948547.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1151..3502
                     /locus_tag="IXT46_002660"
     CDS             1151..3502
                     /locus_tag="IXT46_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAQ4948548.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3582..3977
                     /locus_tag="IXT46_002661"
     CDS             3582..3977
                     /locus_tag="IXT46_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948549.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4302..4919
                     /locus_tag="IXT46_002662"
     CDS             4302..4919
                     /locus_tag="IXT46_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4948550.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            4960..5259
                     /locus_tag="IXT46_002663"
     CDS             4960..5259
                     /locus_tag="IXT46_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948551.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5293..5460
                     /locus_tag="IXT46_002664"
     CDS             5293..5460
                     /locus_tag="IXT46_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4948552.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5505..6110)
                     /locus_tag="IXT46_002665"
     CDS             complement(5505..6110)
                     /locus_tag="IXT46_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4948553.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            6235..9222
                     /locus_tag="IXT46_002666"
     CDS             6235..9222
                     /locus_tag="IXT46_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HAQ4948554.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTK
                     LIKSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITT
                     FSRFVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLA
                     DDSHKEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKK
                     LALLVAFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSD
                     IVDLVMSSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYR
                     KFRKFIPDILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYY
                     IHEYPEQTNKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLL
                     EQLDLPSSANEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKE
                     DKSFRRRIQQLLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSE
                     SCNIGFSPVSKEGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDG
                     HMASADGIRYITPQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSL
                     YLLEGFLNQPSELTPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDAN
                     AHYGELDTLSQNSINMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGK
                     AITEYGKVYKTKHQLRYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYD
                     GMEEQLNALGLVTNAIIYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVG
                     KYTFRYEAELSNGKLRPLNVEEF"
     gene            9371..9580
                     /locus_tag="IXT46_002667"
                     /pseudo
     CDS             9371..9580
                     /locus_tag="IXT46_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346508.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3286 a         1461 c         1851 g         3037 t
ORIGIN      
        1 aaaaaatgag tttgaccaaa aatatctatt ctatgtcaga tgaagaattg tataaagaat
       61 ttggtgattt atccggggaa cagttagaag aaagtattcc aggaattagt gactcagata
      121 aaattgttgt cttgtctgct ggtgggcaat taatgggaga tggcaaatcc gaattagtta
      181 gttataaaca aaatcacaga cagtttattg atgttaatac tgattccaac gctatttcga
      241 ttaaggatct aaaagagctt ttaaatagta aaagaaatga attaaagcag ataaaagaaa
      301 ctaattcagt ggaattagag taaaggaaga ttcattatga aaaagatttt tggtgtttct
      361 gttgggctac ttatgatgtt aacatttgga aatgcagtat atgctgctga gaaagaagtt
      421 atttcagatc cagagcagta cgcctcacga tactttgctg attttgaaga agaagataaa
      481 gtacttgcat tgccagaagg tggtttttta aaaggggaag ctaaaattgt atctatggat
      541 aatccagata taattcaagg ttcatataat tcagaaactg atcctgcttc agtttcagtg
      601 acagaagcaa aaaaaattgt tgctgaaaaa ttcaaaaatg atattgaaac tactccaatt
      661 atgcctcgag gagcatttcc acccgatgtt ggtactagcg gacaccttct tgtactagca
      721 ggaggaggaa gctataaatc acagccattt agtggtgcgg gatggcgttt tggaggtatg
      781 ggtgtaaaac cagctgatgg tacaggcaac tttttacgtt ggaaatccta cattgacgat
      841 ggaagagtag gaaatgtaaa tcaagccaac gcaactaaat ctggttctat tcaaggaatg
      901 gcattgtatg ctcgtgaagg attcaaatac tttgcaccaa acgggcctgg ttggacaatg
      961 aatataggta tttattacac ttataatcct gttgcaggta cgtattatgt tgttcaaaat
     1021 atttaataaa acagcacaaa gagatttctt tgtgctgttt tattattttt agttgttgac
     1081 aaacactaaa atataaaata taatcaacac ataaacgaac gtatgttcgg caagaaagca
     1141 ggggattttt atggatgaga tggttttaag tactcagaaa tggctaaaca agaaatacag
     1201 taatgttaca gggtttgata aggttccaga aaatgggcga acagggtggc ctacaatcta
     1261 tggacttatt gaaggactac aagtagaact tggtattact aatctagtag ctaattttgg
     1321 acctaccact gaaaaaatgt acgataatca ggttactcct aaatggggca aaaatctacc
     1381 taaaaatatt gtatttctta ttcaaggtgc cttttggtgt aaggggatta atccaggtgg
     1441 cttcgatggg gtatatactc catatttaga tactgctgta aaagagttgc agactgatgc
     1501 agggtttaat ggaagcgctg taactggagt tttggatgcg aaatgggcca aagcgttatt
     1561 tgatatgagt gcttttgttc ttgttcccgg cggagatagt aaaattagaa aaatgcagca
     1621 atggttaaat gtaaattatt tagaatacac gggaataatg ccttgtgatg gtatttatca
     1681 aagaaattca aatcaagcat taatttttgc attacaagct gaactaggat attctcccag
     1741 tgaagcaaca gggtcttatg gtaatgggac aactagtaaa acttatcctg tgtctgaagg
     1801 taactcggga aactatgtaa gaataattca atatggatta tatgttaatg gttattttga
     1861 agacggtaca ttcgatggta ttttcactaa atatatgggt ttagaagtac tggcattccg
     1921 aaaatttatg gtattgcctg aatatactga aatagcagat gttgttgtaa taaaaggact
     1981 attgtctagc gctggagata ttagaagatc tgcagatggc gcagatactt ctacgcaatt
     2041 aactagatct caaatccaaa cattggttga taatgatata aaaatagttg gtagatatct
     2101 tactggtact gttggaattg gaaaagatga acgaaataag tatctaacta cagaggaatt
     2161 gaataatatt ttttctaaaa atttatctgt gtttcctatc tatcaagatg gaggtgcagc
     2221 attagcttat tttacttatg atcgtggctt atcagatggt aagaaggcta tagatgcagc
     2281 aaaaaatcta aatataccat taacaacagt tatttatttt gctgttgatc tagacatgtt
     2341 aggggaagaa attcttgcat atgctggaga atattttaag ggggtatctg ctgtaatgtc
     2401 atatagcggg tatcaaacgg gtgtttacgg aacaagaaat gtttgttctc aaataatcaa
     2461 taacgggtat gcttcgtttg catttgtttc agatatgtcg actggttata gtgggaattt
     2521 aggttttcct atgcctagac aatggtcttt tgatcaattt gttgaattta ccataggaag
     2581 tggcaacgga gctgttggta tcgatttaat cgctacatcg ggtagagata gcggatttaa
     2641 tgagttatca aatgatacta ataatgataa ttacattgcc aaatacaatc agaaggttat
     2701 aaatcagatg gtacgtgcgt atcaatatct atcacaagct ggtcttgata atccttggaa
     2761 ccctcatttg acattttata gatatgtaaa ttattctggt ttgtcatggg acatcatttc
     2821 ttctcctgta acagagcatg atagaaaaat ttatgatgaa tataggaata aattaactaa
     2881 tagcgagggc ctgtataatt attttataga tcctaatact ggttcaataa taggtttgcc
     2941 tcacttaatt gtgacgttac aatcacagat gtttctagcc gacacaatca atgatagtgt
     3001 ttctgacttt gcaggttggt taggagattt aatgacttgc tggggtgaag ttaagaaatt
     3061 aggaatacaa atggagcaag gtgtatttgc attagtaggt acggctgcag gtggaacatt
     3121 tagtctagaa gatttatacc aagatgttga cgcggtaaat gtttatacct tagcaaaaag
     3181 aaattctgat tcaacagctt tatcggcttt aaaaacgtac tattgtgata agggtgctat
     3241 tgatagattt aatcaatttg ttaagaacag atttggttct tcagataaaa tcgcttcagt
     3301 aacaaatagt ttattagaaa atgacgaaac agttgatatc ttaggtgtag ggataatttc
     3361 atttttcatt gataaaatag ttaataattc acttgggaca gattttactt atcttgattt
     3421 tattggagat gaggggaaag ttgcaaatgg attttctgaa aaaattattc aatttcaaga
     3481 aaatagaagt aaacttaatt aagaatcgtt tactatttaa acagtgtcct tttccttttt
     3541 aaatatatac gataaaataa gtatatgaat tgtaaaagga catgatgatt atggaagaaa
     3601 tagaatggaa taatctgact caaaataata aaaataattc tggatgtgga attatcttta
     3661 tgtttgttat agttttggga atagtagtac ttttaataac tgtcaagata gtagattact
     3721 ttgcgaatac tcctgaagaa caaatacaga gaaaacttcc tgagtttgaa agagtaccac
     3781 cttatgatcc aagagataat tcatttcaag taaaaaaatt aaaagagtct ccaaatgaaa
     3841 tgtggtttga agttacagtt gaatcaagcg acttcaaaga aaaaaagaaa gaatacaatt
     3901 atattgtaaa ggcaaaagta tcaaaaagat ttatttttaa ccctaaatta gaaatatata
     3961 gtgttgtaat agaataatag tgttaaaaaa attgtaaaag ttaaagaagt caaattctga
     4021 tgtgaaaaat aaaatatacc atggaagaca taaaagaaaa actggataac tagtttattt
     4081 aatggcagac cgttaaggcc tgccattttt atgtatttta gcggaataaa tataatcatg
     4141 cgggagtgta aacttactgt ttcaaaaagt atactttttg acatgccttg attttctttg
     4201 tttatgtatg gcataataac cacataatac aatttgaaac gtttctgatt taatctgatt
     4261 gttttgaaac aattttagtg aaaaaagggt agataaaaac gatgagaaaa tttttttata
     4321 tccgggtcag tagttatgat caatcgatcg aacgacaact gatttccgcg aaggaattag
     4381 gaatccctga agaatatata tttgtagaaa aagccagcgg caaagatttt aaacgccctg
     4441 aatatcaatt aatgaaacgg atgtttcgaa aaggagattt actctatcta caatcattag
     4501 atagactagg cagaaataaa caaatgattt tagaagaatg gcgagaatta actaaggaaa
     4561 agcagattga tatttctgtg ttagacatgc ctctgttaga tactgctagt tacaagcaac
     4621 tagatgggtt agagacgctt atctctgact taattctgca attactcagc tatatggccg
     4681 aagacgagcg gaaacgaatt aatagccggc aaagagaagg cgtagaagct gcgaaacaaa
     4741 agggtgtaaa attcggcaga aagaaaattg ctttacctcc tgaatttcct gcgatctatt
     4801 ctgactggaa agcaggaaag ataactgcag tctatgctat ggatcaattg ggcatgaaac
     4861 gaaatacctt ttatcgacgg gtgaaagaat atgaacatac cttgcaccac ttttcttgat
     4921 agatataaca gctattagac gggaagggag agtttgaaaa tggacttaac gaatcaaagg
     4981 gtcgttttta ctggaacgct gcagcaaatg acacgaaccc aagccatcgg tttggttcac
     5041 tctttaaacg gccattgtca atcaagtgtt acttcaaaaa caaatttcct ggtttgtggt
     5101 cagtattcta agtcgttgtt tgatgattct ctctatacaa aaaaggaaca aaccgcgcgg
     5161 gacttgattg cgttaggtca tgagattacc attttatcag aagtcgaatt ttatgcgtta
     5221 attagtcaac agttgaaaga atggcaacgg tatttataat cgttagtaaa atttacaagg
     5281 aggaaaattt ttatgaagcg aaaatcttat gatcgttggg gcattgaaat aactagtttt
     5341 aatcgaaata ttgcttttca cgtggagtgt gactgtgggg aattagcaaa aagtgtttat
     5401 caaaaaaatt acttttactg tcctaaatgc catcgccgat acggggtaca tggaacatag
     5461 aaacgaaata gtgcggtaga aaagcgaatg aatgtagtat atttctacaa atcattcgct
     5521 ttctttattt tataaatagt tggtcgagag atcccgtttt cttttgcaat ctctgcaact
     5581 ggaatgcctt gctttaacat gtccaccacg gttttaaaaa ctaagcgttt ttgcggatct
     5641 gttgagttaa tagaatactc gattggtcgt cccttatatc ggccggcttt ttgagccaat
     5701 aatactcctt gccgctgacg ttcacgaatt ttctcacgct cgttttgtgc aatataactt
     5761 agcagtgata aaaacatatc gaacatagcg gtatccagga gttcatttcc agtattaaaa
     5821 tctaaaaact gtgcatctaa tatttttaac gctacttttt tctgtttcat aaaagcaact
     5881 gtatttttta tatcttcata atctcttcct aaacgatcta gtgatgtaac gatgacgcaa
     5941 tcaccttcac ggatataatt tagtaatttt tgaaactcag gacgctcagt atctttacca
     6001 ctggcttttt cttggaataa tttatcaatg ttaagtcctt ccatcattgc caattgtcga
     6061 tccaaatttt gatcttgtga agatactcga atatagccaa tttttcccat aaaaaactcc
     6121 tttttaaaag tgatataatt tacatgtaaa atttacttgt agttttactg ctatcatagc
     6181 atttttaaaa ataaatttta tgtagactta aaatttactt catggagggt ttaaatggat
     6241 gaaatcaaaa gtaacaaaaa agcatttggc atttatttag gagaacctag tacagaacaa
     6301 ttaaaccaat ttttttattt gcatgaaaaa gatttagaat tgatggagac tatacgacga
     6361 ccagctacta gattaggttt tgcactacag ttagtctcac tacgtttttt aggaactttt
     6421 atattagatc ttaccaatat tccccaaaat gtattgagtt atgtagcaac tcaactaaat
     6481 attgatcctg gagaaattat ctactatagc aggagacaga ccaggtatca gcacacaaaa
     6541 ttgataaaat cacattatgg atatcaagat ttcaaccaac cggaaataga aacataccta
     6601 gctaactggc ttttaaatag agcgctgtat acaacagaat cttcagatat gttgtttgat
     6661 atgcttctaa aaaaatgtct ggatgaaaag attgttttac ctggaattac tactttttct
     6721 cgttttgttg ctagtgcaat tgaaaaagct gaagagcatt tataccgaca attgtctttg
     6781 gttccaactg aagatgagag aaagcggctt ctcaatcatt tagaattaat tggaactcca
     6841 gtttatgggg caataatcaa aatggacatt ttgagaaccc cgttagctga cgatagtcat
     6901 aaagaaatag ccagaggttt tgaccgacta aagcaatttc aagctttctc tactgaaaaa
     6961 tggaagatgg aatctattcc tgaagggaaa ataaaagttc ttgcaaatta tgcatttaaa
     7021 gctaaagctc aattaattca acgaatgagt gaacagaaaa aactggcgtt gttagtggca
     7081 tttattttca tatacaaacg taaggctatg gatgaacaaa ttttagcact atctaatttt
     7141 tttgaaactg tttttagacg cgccaaaaat aaggaatcta aagaacgtct tcgtaccata
     7201 aaagatctag atcgagccgc atcgacactt tcagatattg tagatttagt aatgtccagt
     7261 cattctgata ctaatgaact atcccttcgc gatcgtatct tagaaaaata ttctgaggaa
     7321 aatgttaccg aagctgtatc gcaagttcgg ctattggtta aaaatgatcg tgaaccaata
     7381 gccatttctg aacttctgaa cacttatcga aagttcagaa aatttattcc ggatatttta
     7441 actacactaa catttgacag caatgactac ggtaacaact gtaaggaact ctggaccttc
     7501 attaataata gatttcctaa gccgattact tacaaaatgt ttggagctat taaacatact
     7561 cttccaaaga aatggattta ttacattcat gaataccctg aacaaactaa taaatgtgta
     7621 ttgattgcag ctgtcgaatt gttaattcaa tctttaaaac gccatgatat ttatattcct
     7681 cagagtgtct tatataacaa tcctatggat tgcttgattg atgagaaaac ttgggttcaa
     7741 caaaaatacg ttttattaga acaactagat cttccttctt cagcaaatga aatgtcttta
     7801 tggttaaaga acgatttgga actgtcttat aaagaagcgc taaatcgttg gcctacttct
     7861 aaaatggcca gaatagaaaa tgcagatcgc ctggttgtct ctagacttaa aaagacatat
     7921 gaaaaaaagg aagataagtc ttttagacgt cgcattcagc agttacttcc taaaattgat
     7981 ttgtcagatt tgttattgga agtaaaccaa cagttaaatc ttactcaatc atttaaccac
     8041 ttaagtgaca aggacaccaa aatgaaagac ttggatatta gtttattagc agttctttta
     8101 tcagagtcct gcaatattgg tttttccccg gtttcaaaag aaggatttga ttctttaaag
     8161 tatgatcgtc ttgtctatgt caatcatcat tatattcgag tggatacact ttcaggagct
     8221 aatcaaaaaa taatacatgc acacaggaaa cttgccacct ctaagatatg gggtgatggg
     8281 catatggctt cagctgacgg tattcgttat atcacaccac aacgttccct atattctaga
     8341 agtaatccaa aatattttgg ccgtggtcgt gggatcacat tctacaattt tgtctctgat
     8401 caatatatag ggttccacgg aatggtcgtt tcagggacac tgcgagattc gctttacctt
     8461 ctagaaggat tcctcaatca acccagcgaa ttaactccta atcagatcat gactgataca
     8521 gctggttata gcgatatgat ttttggtctc tttggcttat tagggtttca atttagtcca
     8581 agaattgcca atgataaagg aaccaaactt tggcgaatcg acgctaacgc tcactacggg
     8641 gaacttgata cgttgtctca aaattcaatt aatatggaac tgatttatac ccattgggag
     8701 gacattctta gggttgcagg ttcgttgaaa tctggaaaag tgaatgcaac agaattaacg
     8761 aaatctcttc aacggaatgg gcaacccacg cctttaggaa aagcaataac tgagtatgga
     8821 aaagtttata agacgaaaca tcagcttcgt tatatttctg acgaaatata tgcacggcaa
     8881 attttagaac aattgaataa gggggaagct cggcatgcct tatgccgtaa tattttttat
     8941 ggacgaaaag gaaaactcta ccagacttat tatgatggga tggaagagca gctcaatgca
     9001 ttaggattag ttactaatgc catcatatat tggaactcac tgtatttaga aaaagtattt
     9061 gaacaaatga aagctgaagg attcgactgt tccgaagaaa tgatacgcag gcaatctcca
     9121 ctaattagtg atcacatcaa ttttgttggt aagtatacgt ttagatacga agctgaatta
     9181 tccaacggta agttacgtcc attgaatgta gaagaattct agcaatgttc gggttttgca
     9241 tgctaccgca ctatttcgta tgactgttcc agcgaatcac ttcgaataga aaaagagaaa
     9301 aacacgagaa cagcgttaaa tcaacgtttc ttgtgttttt acttttgtgc taccgcacta
     9361 tttcgtttct atgttccatg taccccttta tcaagaagcg caaacacgcc aaattgccga
     9421 ttggttgatc ggcatgaacg caagcccttt atataccttg aatttacaac aaaaaggcgt
     9481 acaaggtaca ttttcattag gacgtgtaca aacaccgact ttatatctca tttatcaacg
     9541 ccaggaagca atagaaaact ttaaaaaaga accttttttc ctgaataatt catagtttta
     9601 ctaatagtct ttcctaacat tgatttaata gtctt
//
LOCUS       DACGMI010000089         9556 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.092, whole genome shotgun sequence.
ACCESSION   DACGMI010000089 DACGMI010000000
VERSION     DACGMI010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.092"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(59..1822)
                     /locus_tag="IXT46_002668"
     CDS             complement(59..1822)
                     /locus_tag="IXT46_002668"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAQ4948555.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(2043..3503)
                     /locus_tag="IXT46_002669"
     CDS             complement(2043..3503)
                     /locus_tag="IXT46_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948556.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(3711..4637)
                     /gene="glsA"
                     /locus_tag="IXT46_002670"
     CDS             complement(3711..4637)
                     /gene="glsA"
                     /locus_tag="IXT46_002670"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAQ4948557.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQMADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(4660..6087)
                     /locus_tag="IXT46_002671"
     CDS             complement(4660..6087)
                     /locus_tag="IXT46_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4948558.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(6118..7332)
                     /locus_tag="IXT46_002672"
     CDS             complement(6118..7332)
                     /locus_tag="IXT46_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAQ4948559.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(7673..7915)
                     /locus_tag="IXT46_002673"
     CDS             complement(7673..7915)
                     /locus_tag="IXT46_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4948560.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(7947..8504)
                     /locus_tag="IXT46_002674"
     CDS             complement(7947..8504)
                     /locus_tag="IXT46_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4948561.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(8517..8705)
                     /locus_tag="IXT46_002675"
     CDS             complement(8517..8705)
                     /locus_tag="IXT46_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAQ4948562.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(8718..9284)
                     /gene="amaP"
                     /locus_tag="IXT46_002676"
     CDS             complement(8718..9284)
                     /gene="amaP"
                     /locus_tag="IXT46_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAQ4948563.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         2863 a         1971 c         1581 g         3141 t
ORIGIN      
        1 atgaaaaaac catccagata ctagtataaa caattatctg gatggtgagc ataatgaatt
       61 attgaatatt caagacacgc agactatctt caacgatttg ttttggtgtt aaatgataac
      121 gttcataaag ctgccctaca ggaacgctat ccgtgaattc tttctctgca ccaaaattta
      181 atacgttcat tgaagaatca ccataataac gactgatatt ttcgccaaat cctcctgaca
      241 aactaccatc ttctaatgtg atgactaatt cgtgtgtttc ttttaattta tctaatgttt
      301 ctacgtcatt ttctgtgatc gttcctggat tgatcaacgt tgcttcgatt cctttttttc
      361 taaaagcttt tactgtttct tttcctaatt caagaaaacc gcctaaagct aaaattgcta
      421 cttttcctcc attatttact gtttgatagg ctggaatact ataatcattt gcgatagctg
      481 taccatgttc tacaccatgt gtaggaattc ggattgctac aggctgcgct gtttgttcga
      541 acgcccaatc tagcatagag atcatatcct cttttgttgc tggagcaaga tatttgatgt
      601 tcgggatact tgataagtaa ggaatgtcaa atgttccttg gtgtgttcgg tcactagctg
      661 agatcgttcc gccaccgact aaaataatca ctggattctc gttgatcgct aaatcatgtg
      721 ataattgatc atatgcccgt tgcaagaaag tacttgattg gaagacgact ggacgtactc
      781 cctgagaagc caaagcagaa gcgaaagtga tagagtgctg ttcagcgatc cccacgtcaa
      841 aataatgatc tggatgtttt tcttggaatg ttttcagtcc aaaggcgcct ggtatcgctg
      901 cattgactgc ggcaatagga gctgtacttg tttgcatttt cttatccaaa taatccatga
      961 tgatcatatt aaatgtttct ccagaagtta cttgctttgc ctccccggtg gacagatcaa
     1021 atggtacatg ccaatgatat ttcattttat tatcgattgc cggctgataa ccgcgacctt
     1081 tttccgtatg gacgtgaagt acaatcggat gatcaatatc ttttacttct tcaaataaac
     1141 ggatcaccgt ttccagatcg tttccattat ccacgtaacg ataatcaaat cccattgctt
     1201 taaataggtt attgctgctt ttaccgttgg tttgacgaag ctcagctaag tttttatata
     1261 aactgccatg attctcatca atagacatct cattatcgtt tactaatacg attagattgg
     1321 attgtaaaac accaccattg ttcaatcctt caaaagctaa gccaccactt agggagccgt
     1381 caccgataaa tgctaccaca tttcctgatt ctttcttcag atctctcgct ttagctaaac
     1441 ctgttgctaa gctgatagat gtagatgtgt gccccactgt aaaatagtca tgtttacttt
     1501 catgttggtt ggaatatccg ctcacttcac ggtaatgtcc tttttcaaaa ccattttttc
     1561 gaccagttaa aagcttatga ccataagact gatgggaaac atcccaaacg attttatcct
     1621 ttggtgaatc aaatacataa tgaaacgcaa tcgttaattc tactacacct agattcggac
     1681 caacgtgccc acctacatcg ctgtcctttt gcaagatttt ttggcgcatc tcttctgcca
     1741 actgtttcat ttcctcaaca gataattttt tgacatctgc ggggctattg attgcatcca
     1801 atacatgtaa tactgtactc ataatacatt ctctcctccg tactatcttc ttttaatgaa
     1861 aatagatttg ttacacttta tctattctac tacttagagt tgactctaag tcaatagcat
     1921 tttaaaaaaa tttcagagaa agcttgttat ataagtagat cttcgcacga atcaggactc
     1981 aaataaaaac cttctacaga caattaaaaa gctttgtaga aggtctccta attaaggtct
     2041 catcaagaaa tatgtttttt taataggtga agttcctgag caatatgata caaatggatg
     2101 tttgcacctt ttaatgagat tggatagatc tttgtctttt cagtttctaa tccattttga
     2161 tagctagcag catcgcacaa aaccactctt tttttcgcac atagacattc atcaggcaat
     2221 tcttctaatg aacgaaataa aataggattt atttcagcga tgccttcttc cgcatacaaa
     2281 tgaaattggg ttcgataaaa aaattgtttg actgaacttt ctgaaacaac aaaaatttct
     2341 atttcctgtc tccccgcttg ttcactgttg atcaaagaaa gacttttgac gaattttcga
     2401 atgaaatttt cattccatct tagttggatt tgatttttct ttttccactc ttccaatatt
     2461 tctacaattt ttccgtacag aagttgttct ttttctgata gaagatagat cctttccggt
     2521 aaaaatactt gtccatctgc ccacaacgta cggacaaatt gtaaaaagga ttgcttgaaa
     2581 ataaaatttt ctgcatcgtc gatttcagcg atactaataa tctgtaaaat caattcattc
     2641 agtgataggt cattgagaac aaaattttta taaacaactt cgaaatcttt tcttaacagc
     2701 tccatgttct cattggtata atttctactg ttgaacaaag aaaaaatata atagacatct
     2761 tcttcttgta agtctagaat tcctttttgc tcttccaatc cttgacagac taattgaaat
     2821 aacggcttcg tttctgcgct tttcttatct tcttctttca gtccaagggg aaatgccttt
     2881 cttccgattg cgatctctat tcctcgtatg ataaaggact tttcatcttc cgaatatctt
     2941 cttttaaaaa aatgagtctc tacataatca atcaactcgt tacaagcttc ttctacatac
     3001 ggatttttat tttcatagcc ttcccaattg acataacgta ctaaagctag caagatgttc
     3061 cgcgagtcaa attctgggat aatgatttct ttatttttca aataatcatt ttctttaaaa
     3121 aaatccaata cgattttttt gattgtatat actttgctca aagaaataaa ttcaagatca
     3181 gccagttctg tactcgtgaa tataccatta aaataataac ttaaaaactt taaaaaataa
     3241 gattgaccgt acagaaactg tgtgagctca gaaagagcaa taccatgttt gaatacgagt
     3301 ttatacttat gcttctctct tacttgttct tttatacaat attctagaca ctcggctaga
     3361 ctttctagat cgtgaaggat cgttggtgta gtcaccctta gagaaatagc tgtttgttcg
     3421 atgtctattt cttggaattc aaataattgt tcacacagat acacttttct aaatatattt
     3481 cgctcgatgt aattttccag cattcctgat acacgcctcc agtttttctt atgattttat
     3541 ttaatcatat ctgtaaatcg tatttttgtt tcctttttat ttagaaaagc cctttcaaaa
     3601 accaataaaa aaagaaactg ggacaaaagt caaacaagct cacaatttca gcctcattgt
     3661 aggtagcttt gagccgtttg gacttttacc ccagcctctt tcaagaatgg ttattcaaag
     3721 atgtcagcgt ctagttcttt gactacatct ttcaacaatt ggataccagc tgcgctgtta
     3781 ccaaatggat ctagtgccgg gctgaagaca cctatgccgt aacgatttgg cacagctgcc
     3841 atcaacccgc cgcctacacc gctttttgca ggtacaccaa catggacgga aaactctcct
     3901 gattcatcat acaaaccagc agttgtcata attgatttga cgattgtagc actttcttca
     3961 gtaatgattt gtttgccatt ccaaggagca attcctttat ttgccagcac agcagctaat
     4021 tttgctatgc ctgtagcggt gacattgagg gagcattgtc tgaaataagc atcgagtatc
     4081 tccggtacgt ctccttcgat catttgatta cctttcatat agtaagcaag agagcgattg
     4141 atatcacctg ttcttgattc agaatgatag atttcttcat tcaatgtgat attaggatca
     4201 tcacagatct ctttcataaa tgacaagatt cgctcaaatt tttcatctgc atctttaccg
     4261 gcaatcaacg aggttgttgc aatcgctcct gcattaacaa aaggattcat tggatgtttg
     4321 cgatgattga tttccatatt catgatagaa ttgaaggcaa aaccggttgg ttccgtgttg
     4381 attgtttgaa agactttttc tattccgttg tctttgattg ctaataacaa tacgggaact
     4441 tttgacatgc tttcgatggc aaagcgcaca tcggcgtctc ctccctcaat cagttgtttt
     4501 gtatccaaat cataaatcgc catacctaat tgtttgggat ccacttcagc taatgctgga
     4561 atgtaatccg ccatttgtcc tgtttgataa tagtggaaat tttttccaat caattgttct
     4621 aattctttta cttccatttg aataaccagc tttcattttt tatttttctg catgctggaa
     4681 tttatgacgg catgcgtaga tcgtaaatgg aataactaag acgataagat aagaaacaat
     4741 cagaatcgtt tcataaatcc catgctgtcc agctgcgata ctagcaggtg gaacaaatga
     4801 gatacaaaaa gcaaaaagtg aagtcaaaag acctaaacaa gcaacgatta cttttacaac
     4861 ttttccgcct ggaacctgat aggctctttc aagactgtca tctttaaaaa ccagcttcaa
     4921 atagcccgcg aaaaacataa agtacaacat caggtagatt acaacagtca atgacatcgc
     4981 tgcaagaaat gaaagattat tccccccgcc gcttaatgta aagacggctg cccagattgt
     5041 tgcaacgatc ccatttgcga tcatcaaatg agcaggaaca ccgtgtgtgt tttcttttgc
     5101 aaaatattca ggaagtaatc cttcttctgc tgctacgtga agtgcttttg aaggagaggt
     5161 tacccaagaa gcaatttctc cgatgacacc taaacaaaca agaatcgcaa gaattttcgc
     5221 aatccatgca agatttggat caatgtgtct taataggaat tctaacgatt gaatcacccc
     5281 tgtattaaga gacaaaccat gttgaggtac tgtagtagcg acggtcaatc cgccaaaagt
     5341 atctaaaatg attgccagaa taaccaatac aaacattgct aatggataat cctttttagg
     5401 gttttccatt tcatttgcat gactggcaga tgtttctacg cccatatatg ctaaaataaa
     5461 ggaaacaaaa acaaccagcg taggcaattt cgaaaaatca ggaatcaatg ttttcataga
     5521 cagtatcgtt tgtagtggag cgcctgaagc gacataatgg atccctaagc caaacaagac
     5581 taatgctggc aacaagatac cagctacaaa accgatccga gcaatcaatg aagtgtattt
     5641 ggttcctttt aactgtgaga gtaaaatagc ccagaaaata atcaatagga ttgccaattt
     5701 cagatattta ttgttttgta tagcaccaat acccgttgca taggataatg caccagttaa
     5761 gaaatacagc atggtcaagt agccaactgt tatctcaaac cattggaaaa agattgcggc
     5821 aaaaccgaat cgttttccca atgtgcgact gacccaagta tagacaccgc ctttttccca
     5881 tcctttcacc gttgccatct ctgctgcgca caatgccaca gggataaacc atagcaaacc
     5941 gcctaataac aagaaaaata ctaagctgaa gcctgaggtc gcgaatgtgg gatattcata
     6001 taatgaaacg accattgaga tggtcatagc caaaaagcca aagaacgtta atttttttgc
     6061 aggaattttc gttttgcttt gttgcatgaa tcttcctctt ttctatttga atttgtttca
     6121 attgagtttg ttgccaaaga agaaaaagtc caatccttct tcttgttctt cttttgtagt
     6181 agtgatcgtt gtaaagtgca tcgccgattt taaaatcact gttgtcagca cataggcata
     6241 cacggcagta atgatgacac caatcacttg aatccctaag aagtaccagc tgcttggatt
     6301 cgttagtaaa tggctgttag atgcaaagat ccctatcaga atcgtacctg tgaatccgcc
     6361 catgccatga acaccccaca catcaagtgc atcatcccat tgtttctttt tacgaaaatc
     6421 aacagcagca tgacagacga tacccgcaat gatcccaatc agcatggcac tttttgcttc
     6481 tacataaccg gcacaaggcg taatggctgc caatccagca acggatcctg ttagtacgtc
     6541 gacaaaatca aagccatttc cttttacttt tgcaatgatc agccaagtaa tcatcgcaaa
     6601 tgcaagagcg atgaatgttg aaccaaatgc attgactgct tgttcatctg ctcgaagtgc
     6661 accaccggaa ttaaaaccga accagccaaa ccaaagcagt cctgtaccga tagcagctgc
     6721 cataagactg ctatgctgac ttctttctcc taaaggaatc tttctttgac caagtgtgag
     6781 gatacatgct aaagagccga atccagctgt cgtgtggatg actgctccac cagcgaaatc
     6841 tctaaatccc atctgatcca aaaatccgcc accccatatc cagtggcaaa cagggaaata
     6901 aatcagcaga ttccaaaaaa taacaagtat aatatagcct tttaaattca atctccctgc
     6961 aaaagctcct gtcatcaaag gaacggtaat cacgataaac atcagttggt aaagaaagaa
     7021 cattaaaaat ggaatcgttg caccatgaaa catgttgggg aagcttgtaa catgtctcat
     7081 caaaaagaaa tctgccgggt ttccaataac accgccgata tcccgtccaa aggccaatcc
     7141 gaatccacca aatacccaca taatcgttgt tatcccaacg gagagaaaag attgagacat
     7201 gatcgttagt atattattct tccgtgctaa tccgccgtaa aaaaaagcta gaccaggagt
     7261 catcaggcaa accattgctg tacataaaat catgaatgct gtatctcctg tattgatagg
     7321 taatgtattc atttttttcg cctcctttct acgattacga gtataaaaga aggtgtagtt
     7381 gtttttttct tctgtttttt tgaattaata cttgcattta taaaagacag acaattaata
     7441 aaagcttgat gtgttgtgct ctttttcgtt tttcacacaa ataaagacaa aaaataaacg
     7501 gtcttctttt tatagaaaac cgtttatttt cgtctttttt tatttttaaa gatatttttt
     7561 cataaggaat aaagaatact tcatataaaa tatataaaaa agaaccgcag cgagtgtcgc
     7621 tacggttctc aaatttgttc ttcatttcaa cataagtttt tcttcaattt gcttataatt
     7681 tacgtgcaaa gaatgaaacg actaatacta aaatgattgc accgatcaat gatggaatga
     7741 tagccattcc tgcaattgtt ggtccccaag ttcctagtaa agcttgtcca attgctgaac
     7801 ctactaaacc agcaatgatg tttgcgatga tccccattga tgatccttta ttcgtgattg
     7861 ctcctgcaat tgctccaatg ataccgccga cgattaatgc ccaaataaat cccattttaa
     7921 attcctccta actgacttct tacttcttat tgtacacgtg gttcgttatt ttctttgact
     7981 ttttgtgcac ctttgcctac agcagatttt gctttatctg tttggcgtga agcaaattgt
     8041 cctgtggatt ttgctgcttc tgttactttg tcttgtactg tttcttgatc tttttggtat
     8101 tcttcttgtg ttttgatgtc tgcaacattc acattcactt cgataacatc taaatgtgtc
     8161 atattgttta cttcagtact gatcaattct ttgatttggt tgtaaatatc ttcgatgtct
     8221 ttaccgtatt ctacgatcac atctagatcc acagctactt gtttcttacc tacttctgta
     8281 ttgatacctg ctgttacgtt atctgtgttg actaattttt cagccatatt tgagaaaaat
     8341 ccgccatcta atgtcaatag accatctaca tctttcaatg cataaccgat gattttttgg
     8401 atgactttgt cttcataagt caattcacca ttcatcatgc ggttttctcc tttttcattt
     8461 gccaaaactg atccatttgt tgtattcatg tttttgtttt ccatctttgt ttcctcctat
     8521 gatttaaaaa attgatcaac tattcctgac tgtttcaaat aaaaaccgat tcctgcgcca
     8581 attgctgtca tgattatgat caacaatgtc ttgaaaaatc caatcgttaa ccataaaaca
     8641 gctagcagta gtccaagacc cccaaagata atagggagct tgtatgctga aaatagttct
     8701 ttcattattt ggccctccta ttccactcga gagtgcttgt agtctcttgt atcttcttgt
     8761 tcttcataac cgctgtatgt gactgccact ttgaccgttt cttttgttcc gagtacttta
     8821 gttacttctt cttcgatatc ttgcatcaat acacctgttt tccctactaa tgaagaagtt
     8881 cgtttcaagt ctccgttgac atggatatgg attcgatttt tcgttgaacg tatccgtact
     8941 ttaggtgaat gaatgaactc ttcttcgtgt aaatgggaac gtaccaaccc ttcgatcgct
     9001 tttttgtcga ttgttagttt gccatcttcc cgtttcataa cgaaagttcc tcttgacttt
     9061 ggatagaaaa gaacgactag caagatgata atagcaagaa cggcaaatac tacagctgcc
     9121 cagaaaatat attgttgcat gtagtaattc gttaaagtaa agaagcgaaa tcgttccaat
     9181 tgttcaggca taatatacgg cgcattgatc aacgcaatcg ctagaaatac tgaaagtagc
     9241 agtaaactca tgataacacc gattattttt aaccccttat tcattttcca cctcctataa
     9301 acttattttt accctgtaaa taactctacc gacaatcaca gtatagatag cgaacagtta
     9361 gcatagcatc agtaaataaa gcgctaccaa acattgctgg atcataacgg cgttttattg
     9421 ccagtctgat actgaaataa caattgctta cttattctct atttactttt gattgctggc
     9481 tatacttaaa ggatattatt caagattaaa aattgcaaag attatgctca gttattatta
     9541 caagattcta tttatt
//
LOCUS       DACGMI010000090         8809 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.093, whole genome shotgun sequence.
ACCESSION   DACGMI010000090 DACGMI010000000
VERSION     DACGMI010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.093"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            21..1235
                     /locus_tag="IXT46_002677"
                     /pseudo
     CDS             21..1235
                     /locus_tag="IXT46_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1414..1749)
                     /locus_tag="IXT46_002678"
     CDS             complement(1414..1749)
                     /locus_tag="IXT46_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4948564.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(1733..2005)
                     /locus_tag="IXT46_002679"
     CDS             complement(1733..2005)
                     /locus_tag="IXT46_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAQ4948565.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2456..3259)
                     /locus_tag="IXT46_002680"
     CDS             complement(2456..3259)
                     /locus_tag="IXT46_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAQ4948566.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3237..4361)
                     /locus_tag="IXT46_002681"
     CDS             complement(3237..4361)
                     /locus_tag="IXT46_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4948567.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4377..5192)
                     /locus_tag="IXT46_002682"
     CDS             complement(4377..5192)
                     /locus_tag="IXT46_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4948568.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5182..6063)
                     /locus_tag="IXT46_002683"
     CDS             complement(5182..6063)
                     /locus_tag="IXT46_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4948569.1"
                     /translation="MSEMKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAP
                     TKEFVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNL
                     YKPLFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAG
                     ITAWKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVM
                     TIVQGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAV
                     FLGVIFKFVEKGVYYEN"
     gene            complement(6139..7428)
                     /locus_tag="IXT46_002684"
     CDS             complement(6139..7428)
                     /locus_tag="IXT46_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002581297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4948570.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7656..8300)
                     /locus_tag="IXT46_002685"
                     /pseudo
     CDS             complement(7656..8300)
                     /locus_tag="IXT46_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2728 a         1873 c         1408 g         2800 t
ORIGIN      
        1 gtcctatttg acaaagagcc aagaaaaaga cgttggtcgt cgatgctgtt ctctcgccta
       61 ctcctcgtgc ttgtagaagt tgtggttcta ctgtggtaga tggaaacggg aaagcaatta
      121 tagtgaaaaa tgggaagaag gaaacgattg tccgttttga acaatacaat catatgcctt
      181 tggttacgcg cctaaaaaag caacgctata cctgtaaaaa ctgtcgtacc cattggacgg
      241 ctcaaagtta ttttgtccga ctcagccatt caatcgcaga tcatgttcga tataaaattg
      301 cttctttact gactgaaaaa gtatctttgt cttttattgc gaaaagttgt caggtatctt
      361 tgactaccgt tactcgtaca ttgaaagagt ttaaaagcta tttaccaaag ccttctaaga
      421 agattctccc cagagtattg atggttgatg aatttcgttc gcacgcttcc atagaagata
      481 aaatgagctt tatttgcgca gatggtgaaa caggaaactt aattgctgtc ttgcctacgc
      541 gtaaattacc tcgattaaca agctatttct taggctgcac caatccagaa gaagtagaat
      601 tcttagtcac agacatgaac gccgcttact tccagcttac caaacgtgtt ctgccaaatg
      661 cgaaagtagt gattgatcgg tttcatattg tcaaacacat gaatcaggca ctcaatgagt
      721 tgcgtatccg tgaaatgaat gagcttcgta aagcaggaca gaaaagtcag gcagaaaaac
      781 tgaaaaagaa ctggcgcttt ctgctaaaaa atcgtgcaag catcaaccat tatgagtaca
      841 aaacatggaa aagtttccga gcaccaaaat acccatttct cactgaagca atgatgattg
      901 atcgattgct tgagttttct gcgcctctaa aggaggcgta tccctttttt catgaattag
      961 tcgaagcctt tcgagacaaa gaccctgact tatttttctc cttattggca gaacttcccg
     1021 aaacgttaga tgacggcttt cgggagaagc ttcaaaacct tctgacctat gaagaaggta
     1081 tcaccagcgc aatgatctat ccttattcca atggaaaaat tgaagcgaag aatacccaca
     1141 taaagacaat gaaacgagta tcctacggat ttaaatcatt cgagaacatg agaattagaa
     1201 tctttttgat caatcaatta atcaatgtaa gataacaaaa aatctgaacc agaatgtggt
     1261 tcattctgac ccggatttga ttttgcacaa ctcatcagtc cttattgaca aagagccaaa
     1321 aatctgagcc agaatgaggt tcattctgac ccagatttga ttttgtacaa cccatcagtc
     1381 cttattgaca aagagccctt ctttttagta ttattataat tcttccatgc gttcttccag
     1441 tcgctgtaaa tcgcttggac ttaattcccc aatttttttc catttgacct ttttgttgtt
     1501 tttgggtaat tcgtttagag ttcctacgtc aatccaagat tcttttttta gtcctgcctg
     1561 tttccaatcc cttatttcaa cgtatttcag ctttatttta tcggatttag tatgatattt
     1621 tgaagtaatt gacagaaacg aaattgtgtc cagtccattt tttagaatat agacaggccg
     1681 gcgtttaccg ccctctgcag ctgtgaaagc aacgtagacg gttgctatat cattagtatt
     1741 catcttcatt gaaccattct tcaatttttt cgtcagtgtc tagtttttgg acaggcaatt
     1801 tttccgctaa tctttgaata ttatggattc gtttactttt ttccgacaat tcaatagaaa
     1861 atgggatttt tccttgctca acaatttgct tataaaaaac ggtgacggct gttttggggc
     1921 tcatgcctag ttcatcaata atgctttctg cttcattttt caatttttcg tccatagaaa
     1981 tttgtaactt agccattttc tccacctctt tctgacaaac acattatatc acggaaagag
     2041 ttcaaatgga attaatacaa ctacttttga actccttgaa atgcagtgta tttatctaaa
     2101 tataaggaaa ggatatagtg ctaaatggcc ttgatagata gaaaagtttc aaaatccgcc
     2161 acagcgataa ttgaagcgaa cactcaacga cacacagaac aggaaaagac tcctaaaaga
     2221 accaaattaa ctaggacgtg tctgaaaact ccacaaagat gtggtatgct ctggtaaaaa
     2281 acgaatggca caaccacgaa gaccgatatg gttcttggaa aactttctcc accctttttg
     2341 taattggagg gatagtggtt tattgatagc gattttccaa gttcttcaag tggaaccaga
     2401 cattgagcac cacggctaaa aagtgaatga agtctttatt tttaatcaat aatttttaat
     2461 gattaccagt aattggtttt ttcatgcgcc ctatttctat ttgatgtgga gttaaataat
     2521 gctgataagt aaaaattttt ccgtcaatta aactgccact agtgaatcct gttctattgg
     2581 taaaaagaga atagtctggg tattcatcta caccaaatga taaagattca gccataaact
     2641 gttttttacc agcaaattca gcactgctac cttgatggat atgtcctaca aaaataccta
     2701 aaatatcact ttcggcaatc aattcagcaa aaccttccgg aacttcagtt acaatagatg
     2761 gatcttccca cgacaatgga tgatgaacca ataaaatcgt tcccttttca gcaggtgtac
     2821 ccaaccactc ttgtaattga atcatctgtc ctatcgatat ttttccttcg tgctgggtat
     2881 cttgagcaga atccaaggaa ataattcgta acccattttg attcgtacaa tggatatact
     2941 ctcccgtttc attgctttca acactcattc cttcaaagaa aacactgcga cgatcatgat
     3001 tcccacgaca aaaatagtaa ggtgtggttg ggaaatattg atccaacatt ttccgtaaga
     3061 cttgataatc agaaatcccc ccttcatgta ctaaatcacc tgttaataga ataaaatcgt
     3121 acactgttaa cgagagttct tgtaacaatt tttccaatgc caactgtgga tttttaattg
     3181 ttggaaatag ttcagcagta aacaagttag tttgatagtt ttctctaaaa tggatatcag
     3241 agagatgcaa aaagcgcatg gctattccct ctttcttcaa taaaataatc aggatatcct
     3301 aaattttctt gcgtctgata atcaaaaaaa tgcattcttt caggttctat gcggagattg
     3361 actgcatcac caatctgcca agtaggtttt tcattaagga caatcatttc tataccatcg
     3421 actttaacgg tgtacgcata actttgacct aatagctcac gatacttcac ttgaccgtgt
     3481 aaatcgcttg tttcttttga aaaggttacg tgttctggtc ttatgcctaa atacaatgag
     3541 ccactaacct gaagaagttg tttttgccaa gctggattca atgttaaaaa ttgactggct
     3601 acctttaatg ttccttgatc ataagtaact ggcataatat tcatgcctgg cgaaccaata
     3661 aaatttgcag taaaagtatt tttaggtttc gtataaacat ttttcggcgt atcaatcatc
     3721 tgaattctac cttcattcaa taaaacaatc cggtcagcta acgtcatcgc ttcaatttga
     3781 tcatgagtga cgtagacaaa agtttgttta taacgttgat gaatttttac caattctttt
     3841 cgtgcatcca atcgtaaacg cacatccaaa tttgataacg gttcatctaa taaaaaataa
     3901 ttactccgtt taaccaccgc acgagccaat gctacacgct gccgttgccc tcctgacaaa
     3961 tctttaggaa gtcgatcttg gtatggcgtt aaacctaaca tcttcaaagc ttcttccaaa
     4021 cggtgctgaa tgtcagctgt cttaatttta ttcgccctta atgcaaaaat aatattctcc
     4081 tttacagtca tgtgaggata taaagcataa ttttgaaaaa ccattgcgat ctctcgttct
     4141 ccacaaggta gcttatttgc tagttgtgta cctaaaaaaa gctctccact cgtaattttt
     4201 tccaaaccag caatcattct cagcaaagta gattttcctg aaccagatgg tcccagtaac
     4261 acaattcgtt ctccagcggc cacagctaaa tcaatttctt ttaaaatggt atgttctcca
     4321 tatttttttc cgatatttct taattcaagc gtttctccca tgatttgtcc tccaatttat
     4381 ttaatacctg cagaaacaaa agtcccgata atatattttt gaaaaattgc atacaagact
     4441 aacggtacaa acattgtaat taaactaatc gccattgcta cggtaaaatt tgtcccacct
     4501 tcagaactaa tataggtctg catcgccaac ggcaaagtat aattatctac tgtccgtaaa
     4561 attaataccg gccaaacata ctcattccaa gaggtaataa aaaaccaaat accggtagaa
     4621 gtaatcgcat gtctagtaag aggaaaaaca attttactca tgacggttgt ttgtttgatg
     4681 ttatccaatg ccgccacatc tagaaggctc actggaattt cccgcattgt ttgcgtcaat
     4741 aaaaaaatgc ccatcgcatc agcaaattgt ggtattatca caccccaagt agtatcaatt
     4801 aaattaagtt ttgcaatcaa caaataatta ggaatcatcg caacagtaaa aggaatgaac
     4861 atcgtaccaa tgatgataaa gtaccagatt ttcttccctt tgattcggca ataagtaaaa
     4921 ctatatgccg caaaaaaagc tacgcctaac ttaacaaccg ttataattgt agcaataaaa
     4981 aaagtatttc tcgtaatttt gataattgga agattttcga acaaatagca aaaattttcc
     5041 aaggtaaacg gctgtggtat caaactagta atcgtctgat aggcatcttt caatggctta
     5101 aaagaattgg ccataataaa caataatgga tagataataa tgattatgat gaacataaat
     5161 aagagatgtg gcaaccagcg tttaattttc atagtaaacc cccttttcca caaatttaaa
     5221 tattacccct aagaaaacag caaatattaa taaagttaaa actgaaattg ctgaagattc
     5281 tccgacttta tacatttcaa aagccttttg ataagcataa tagatcacgt ttgcactacc
     5341 attattcggt ccaccacgag tgatgatctt aatcggagta aacacatact gcagaccttg
     5401 aacaatggtc atcaccaata aatatagtcc tgtcgaacta ctcataggca acacaattgt
     5461 aaaaaaaatg cgccagatgg gtacacgatc caacttagct gcttcgatca tctcttgatc
     5521 aattcccaca attgctgcaa aaatgacaat gaaattataa ccaaaaactt tccaagcagt
     5581 aatacctgca atcacagcaa ttacccaacc ttgtaaattc atccacatag gcagtcttaa
     5641 accaaaattt cccaacaaga cagcaattgg tcccgatacc ggatttaata tccatgtaaa
     5701 aaccatcccc gccactacca aagaaatcac agctggaata aaaaataatg gtttatacaa
     5761 attctgccct ttttctataa ctattcctaa taaaaaggat gtaatatatg ggaacacaca
     5821 gctcagcaag acaaatagaa cggtatagga caaagtattc ttcaacactt tatgaaagac
     5881 tggatcagtc agcaccttta catagttggc aaagccaaca aattctttag tgggggccac
     5941 catattccag tcaaaaaaac tcaaatagat cgtataaatc aatggataaa aaacaaacac
     6001 gcccaacaaa ataattgctg gcgccagata caaataacct acatagcgct tcatttccga
     6061 cagcctcctc atccttatgt caaaagcaga cgaccttgtt tttcctttct tacaggcgct
     6121 gtcgtctgct tgctttgctt atttgagtaa ctcattaatt tccttttgag tagctttcat
     6181 cgtttcattg acggaattac ctgataaaat tttatcccgc atatccaaca atttttgttc
     6241 agcttctaat ccagcatctc caggaaatga actccaactg accatcttat ccatctgatc
     6301 aattgctggt atcatcatct gattttcagc taagaaagct tttaatccat tttgggcgtc
     6361 tgcaacatct ttacgtggtg gtaaataacc agtaccttct gtccatttag ctaaagattc
     6421 aacactataa agatatttta agaaatccca agttgcttcc tttttcttat ccgtttgtga
     6481 tgtaacagct aacattgcgc caccagcagg tagtttaact tttttccctt cccaacttgg
     6541 tgactcaact gctttagcag taaaagtact atttttttga atgttgtccc tttgagcaat
     6601 agtggtatag accatcgcga cgttaccatc aataaagctt tgcacacctt gttcccacgt
     6661 agtgtgtaat gccgtctggt cttttaccat cctttgatat aattcataag cagcgatacc
     6721 atctttagaa gcaaaggtag ctttgccatc ttttattaca cttgccccat tactttctaa
     6781 aattgcttgt tgtgcccaat tatcagcagg ttcttgaata tacacgccat actttccagt
     6841 tttttctttt attatcttag aaaaagtttg aacttcttcc caagtttttg gaccattttc
     6901 atccaagccc gctgctttta atatatcttg atttaaatat aaaaccggat tactaatgga
     6961 gtaaggaata cccacttgtt taccatcttt ttcagacagt gccatgatat tgtctaaaaa
     7021 atgatcttta aaataatcag cattatccgg atccacttct tctactaaag attgaggatt
     7081 agtatatttg aaattttctg caaaataatc tttaaaagcc catcccactt gtactacgtc
     7141 cggtatttct ttggaggcaa cagaagcttg taaattttgc atcaagcctt tatacatatc
     7201 aggattatat tttgctacaa ccttcacttt gtcttgagat tgattgtatt tatctactaa
     7261 ttcattcact gtttttccac ctagggtatc cgcattaaca tgccaatact ctatcgttac
     7321 acgaccctcc gatttttttg ttgtcttggt attcccacta ccacaagctg ccaaagagat
     7381 gacacttaaa acagacacaa cccctataac aagatttttc tttaacataa cattaacttc
     7441 ctcctaattt ctttatggcc atttttctaa tcaagaaata ttatgaacta ccaatgtaaa
     7501 tttctagtta attttctgta aataattcga aatttgtgca tttcggggta cagggtcact
     7561 ggacatatcc atcaagctaa gaataaagcc cccatatggt catgtatccc atctccaaat
     7621 ctcttaactc ctctgttttg attataaaat agtttattct gtgctccttt cttccataaa
     7681 taggcccatg cacaacgtga ggttatatta taaacaccac agcgcgcaag gtactcaatc
     7741 gtttctagtt cattgactgt ccatacagaa aatgtcaatc ctagctgctg ccccacttca
     7801 cgggccaact tagttaacca tccttcatga atattgacga tttgaacgct ttgataggct
     7861 aatttctgta aggtatcgat caaatctgct tcggtaatat ccccaagttt tttcccttcg
     7921 aactgatttt caatattata aaatatatgc tttccccaaa tcgcagccca agataattgt
     7981 acatagccac taagaacaat ttgtggccag atttgatagg tttgtgccag cgaaaaaacg
     8041 gccatttcca atccctcttc ttttaaatca cagttaatgg tcatggttgc cttctcattg
     8101 gccactgctt gaaacacctg ctcaagggtt accgaatctg ggacaacttc ttacctgtca
     8161 tgggctagta ttagcgtacc atctgtttgc tgacgcacat ctacttcaaa acaaagctgg
     8221 cgatccaaac aaaagcgaag aaatgcccag ctattctcct ccgtattgtc actaccagag
     8281 tgtgcagtga tcatggtcat tttgacccct cctttaattc cgtgattttc tcccacacgt
     8341 ccactatacc gatgaagcgt taatttcttg ttaatttctt gtaaattccc tgcgtttttt
     8401 cagtaaacta gttgtaaatc ttgcatgctc cttcctacga actcatgaat cgtcgatttt
     8461 gcccttctag ctagtttcac caattaagta gttctacatt ccccgctttt aacctactac
     8521 accttttttt gttttcagct attccttctt cttgctgaaa gtccttgagg ttctttctta
     8581 caggatacca tcaaggtgtt caatggctta ttcccattga atgaccgaga cttactatca
     8641 gatttctgct cgttgaacca agtctttgat acaggatttc ttccgtcatc ttctcacaaa
     8701 taccaccttg cgtttctcta gcgattggtc gatgtgcacc ctcccagtgg actgtcacta
     8761 cccctttttg ctatgcctag cccacaaaaa aagctgtcct cacagacag
//
LOCUS       DACGMI010000091         8562 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.094, whole genome shotgun sequence.
ACCESSION   DACGMI010000091 DACGMI010000000
VERSION     DACGMI010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8562
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.094"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(139..1092)
                     /gene="menA"
                     /locus_tag="IXT46_002686"
     CDS             complement(139..1092)
                     /gene="menA"
                     /locus_tag="IXT46_002686"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAQ4948571.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1105..2208)
                     /locus_tag="IXT46_002687"
     CDS             complement(1105..2208)
                     /locus_tag="IXT46_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAQ4948572.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2298..3233)
                     /locus_tag="IXT46_002688"
     CDS             complement(2298..3233)
                     /locus_tag="IXT46_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAQ4948573.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3535..5469
                     /locus_tag="IXT46_002689"
     CDS             3535..5469
                     /locus_tag="IXT46_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4948574.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5926..6342
                     /locus_tag="IXT46_002690"
     CDS             5926..6342
                     /locus_tag="IXT46_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAQ4948575.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6356..6922
                     /locus_tag="IXT46_002691"
     CDS             6356..6922
                     /locus_tag="IXT46_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAQ4948576.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6945..7931
                     /locus_tag="IXT46_002692"
     CDS             6945..7931
                     /locus_tag="IXT46_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAQ4948577.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8086..>8562)
                     /gene="scm"
                     /locus_tag="IXT46_002693"
     CDS             complement(8086..>8562)
                     /gene="scm"
                     /locus_tag="IXT46_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAQ4948578.1"
                     /translation="STDTSASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSST
                     TTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNR
                     TNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
BASE COUNT         2518 a         1655 c         1737 g         2652 t
ORIGIN      
        1 aacctcctga taaacggtgt tcaaaagctt gcatctgcgg taataagccc aaccaaacga
       61 aaaatataag gagctatttt tatttggctg ttcttattac ttgatgcagg gcagtttttt
      121 cacaacctct tcatgctgtt aaatggcttg cataatgatt gttagtaata gccccaatac
      181 ataactggca ttgaataaga ccatattttt gatggaatag ctgaaactga taggctgggg
      241 taacgtttgc ttgaattgat ccaaatgctt cttcacaatt ggcaaggtca agaaggtgac
      301 caagatcggc cattcataga taccgctcaa caaccccatt aaaatcacga aatagcaagc
      361 atacatcaat agctggaata agactgttcc cgcaggacgt ccgatataaa aaactagtgt
      421 atagcgatga ttttcaatat cacggtcaag atcccgcaaa ttattagcca acatgatatt
      481 ggcaatcgta aacaccaagg gtaaggaagc taatacgatt gctgctatag cccaaagatt
      541 tcctaccaaa tcaaattgtc cagatgaaaa gttgactgtc agatcataga catctgaacc
      601 gaatgtattg acataaacga ccatggcaaa aattccaagg cccatagtca ccccactgaa
      661 aatttcccct aaaggcattc gagataaagg aatcggtccg aatgtataga atactccaat
      721 aaaacaacag ataaatccca tcaaaagtaa aagccaaccc gtattgatcg ttagaataac
      781 gccgataaca aaaacaaatg caatcatagc taaaatcatg tttcgaatca atacaggaga
      841 tagatttctg cggccaatga cattttcttc atacttatat acttcagaat gagccttttc
      901 ataatccatg taattattga tagcggtagt cgctaaatca aaaactagca ttccaataaa
      961 aaataaaaaa gtgtttagcc aatgtatctc atgaaaaaaa gcgatagaga ataatacccc
     1021 taccgcaaaa ggaaatacac tagccacctt tgttcgtatt tcaactactt ctaaaaagat
     1081 ttttagtgtc atggttcgta ctccttattt tagttcagaa cggtcaccca tcgtgtaatg
     1141 ggagtcctcc gataatttga aggtgtcttt gattggatcg gtcacatata ctttatcgtc
     1201 ttttgtcacg aagatcgctt ccgtcccgtt attcaattcg ctttcgacgt attccagtcc
     1261 ttttttcaca cccattgaaa agactgctgt agacaacccg tcaccatcaa ttgatttatc
     1321 tgttatgatc gtgacacttg cgatatcatt gtcgaacgga taacccgttt ttggatcaaa
     1381 caaatgatgg tattttttgc catctacttc taaataacgc tcgtaaattc cagaggtaac
     1441 taatgttttg ttccgttctt taatagaacc taaaacagat ccgcgagcca tgttcggatc
     1501 ttggatgccg actgtccagt cttggttttc gcctcttggg ctgtggccta agacatagac
     1561 attaccgccc aagtcaacga tggcagtggt cactccttgt tttttcaaga ctttcactac
     1621 ttcgtccgta atgtaacctt tggcgattgc acctaaatcg atgatcattc ctttttcttt
     1681 tagataaaca gttttttctt tgtcatttag ttcgatctta tgataatcca ctaatttcaa
     1741 tgcctgatcg atttcttctt gggaaggttt tctggcgtca tcaaaaccga ttcgccataa
     1801 ttgtgtgatt gcaccaatcg ccatatcgaa tccgccttga gaatcttggc tatattcgta
     1861 ggcccgcttg actaacgtgt agacgtcatc agaaactttt actggtttga tcccagcttg
     1921 ctcattcact tcatcgatct cagaaccttt ttgattgatc gtgattttat caccaagttc
     1981 ttttactcga tcgaaggcag gtttcaatgc tgattctttg ccttcatcat acacacggat
     2041 acgaacgtaa gtccctaaca agaactgttc atcagaatat ggatctttca atatcttggt
     2101 agctgctgaa ctttcagtgg ttgttttatt tgctgagttg ctgcagccag ttagcaccat
     2161 aaaagagatg cccagtgtga ttaaggaaaa tagtagtttt ttccgcatct ttttcctctc
     2221 ttcattttga aaggtgagac gactgcctaa tctggctatc gtcccaccct ccaactttta
     2281 ttagtatgat tatgtgatta tttttctgtt acgatattat ctacttcgat tgtttgagtg
     2341 tcgccttttt cagctgcatt cactaattgt tgtgcgtaca tgatgaatga atgtgagctg
     2401 tgtgtagcac ctgtaacaac ttctacatta gcaggtgagc catcttcttc gcccattgct
     2461 ttgacgaatt cgtcgttcag agtagggatg taagtttttg gttctgtacc gctttttgct
     2521 ttcatatttt cattatattc tgtatcatct tgttttgatt taccgtcttt gtcgatataa
     2581 tcaaagtttg attcagttac tttgccgcca gcaactgtca tttcgaattg cacacggtag
     2641 ccgttagagt agttcttttc ttcaagcttg taagtgccgt ctttcaaatc agcaccattg
     2701 tcgatttcga ttgtatctgt gttaccagct tgagcagctt ggatcaattg ttgtgcgtag
     2761 ttttggaagc tttcagatga gtgagtagct ccagttacga cttccacacc gcttgcgctt
     2821 tgtgctttta agaattggtc attcaactca ggaatgtatt tttctgggtt tgtgccagat
     2881 tttgcttcca tgtttttgtt gtattctgca tcttttgttt ttgattcgcc gttttcattg
     2941 acgttatcat attttgattc agtgattttg ccgtctttta caaccatttc aaagactgca
     3001 cggtaaccat ttgaataatt tttttcttct aatttatatg tgccgtcttg caaatctccg
     3061 ccagctacaa cttttgcaga tgattctgtt gtgctttttg cagtcgaaga ttgtgctgta
     3121 gatgattcag aagaagagtt tgagcttccg ttgtcatctg cgccgcaagc gcctaacact
     3181 agagctgaaa atgctaatac ggcaaatcca gttacaaaac gttttttctt cattttaata
     3241 ccccaccatt ccatttctag tccacaattt ttctttgtga ttcattatac attctaatct
     3301 ttttagccta taagtcaact atttttgata aataacccat gtaatatttc aaacgttttc
     3361 tttcagcaaa tttcgtgaaa aaacgcttta ttttaaaatt tgaaaaaaat ccaaaaggag
     3421 ttagacaaaa gaacagaaca tctatataat atatggagat tgtgtaataa gtatcaaact
     3481 aaaagaatta tcatatattc attatataga tagtctataa ggagcggatg atcaatggca
     3541 aagcaaaata ttgtcgttgt aggagcagga tatgccggtg tttcagctac aaaatacttg
     3601 gcaaagaaac tgaaaaaaga agatgtagca attactctga tcgatcgtca ttcgtaccat
     3661 actatgatga ccgagttgca tgaagtagct ggcggacgtg tagaaccaga agcaatccaa
     3721 tacgatctgc agcatttgtt tgctcgtcaa aagaatgtac aacttgtcac agacactgta
     3781 atcggtatcg ataaagaacg aaaaatcgtc aagaccaaat taggttccta tccttttgat
     3841 cagctgatcc ttggaatggg cggagagccg aatgactttg gtacacctgg tgtcaaagca
     3901 cacggattca ccctttggtc atttgaagat tctgtaagga ttcgggaaca tattgagaag
     3961 acagtagcaa aagctgcatt ggaaccagat gatgaactgc gtaaagccat gctgactttc
     4021 gttgtctgtg gttctggatt taccggtatt gaaatgattg gggaactgat cgactggaaa
     4081 aatcgcctag ccaaagatta taaattagat ccaaacgaaa tcacactgat ggtcgtagag
     4141 gcaatgccga cgatcttgaa tatgttggat cgaaatgatg ctgcaaaagc tgaacgctat
     4201 ttgcgtaagc acaacgtgga attattattg aatgcaccaa tcgtagaagt ggctgctgat
     4261 catatcaaat tgaaagacgg acgcaacatt ccgactcaca cactgatttg gacagctggt
     4321 gtcaaaggaa cttctgacgc tgctgacttt ggattagaat cagcacgcgg acagcggttg
     4381 atcgccaatg aatatatgca ggcaaaaggc tacgaagata aaaacatcta tatcattggt
     4441 gatttagtct tttatgaaga attcccagga acaccgacac cgcagatcgt tcaagctgct
     4501 gaacaaacag gacacacagc cgcagcgaat atcgtggctt cgatcaaagg cggagaaaag
     4561 cataaattta aaggaaacta tcaaggattt atggtttcta ttggtgccaa atggggggta
     4621 gctaacctat ttgataagat ccatttaagc ggatttttag ctatcgtaat gaaacatatc
     4681 gtgaatttga aatacttctt tgatattcgt tctggttatt atatgttcca atatttaatg
     4741 catgagtttt tccatatcaa agatgatcgc aacgtgactc gaggacattc ttctcgttac
     4801 ggcaatgtct tatggagtgt gccacttcgt attttctatg gtttagtttg gttcgttgaa
     4861 gcttccaaaa aaatcattgg gaatggtgaa gtgttcaaac caagtacttg gtttggtgaa
     4921 ggatcatggt tcactggaaa cagtgtgttc ccttggacat gggaatacaa tgtaacagat
     4981 gttgccagtg gtgcttctgc tgctggtgat gcaaccacag ctgccagcgg agcaggggca
     5041 agtgccggag aagcagcgac tcaagctgca cattttggtt tgagttatgc atacggtgaa
     5101 gaaccaatgg ctgtgattga gaagtcacca gactggttca caaagatcat gcaagtgatc
     5161 atgccaaaca atgatgtagc aatgttcttc caaaaattca tggtattctt tgaaattgcc
     5221 ttggcattag cattgattgc tggattattc acatggctat gcagtgcgac aacgattgta
     5281 ttggtgatca cgttctgctt atcaggcatg ttttactggg taaacatttg gttcattttt
     5341 gttgctttcg cattgatgaa cggttccgga cgtgcgattg ggttggatcg ctgggtaatt
     5401 ccatggctac aacgtacact aggtaattgg tggtacggta gaccaagttc ccagtacggc
     5461 aagaaataaa tagataaaga acgttatttg aatgcaagat ttcaatagaa aggggctgag
     5521 acaaaccgtc acagcctcct ttttatgtaa aattaaagga ataagatgcc cgagataagc
     5581 ctccatgagc aagacacagg tgtcacaacc tctgttacaa cctcttgtta taaacggtgt
     5641 tccagaagta gcttcttcga aaaataagcc gaaatttcac aaaaacttga aaagtaattt
     5701 tcgtaaattc cttcttattt cttgaagttg cccacttctg tcacaacctc ttgttataaa
     5761 cggtgttcca cctgctgctt ctcggtaata agcccaaaga attagaaaac atggaaagct
     5821 gttttctatt cttcgttctt attactcaaa gcaagacaca ggtgtcacaa cctcttgttt
     5881 ttatgctaaa attgggtgag ttaatctgga aaaaggagaa caaaaatgag ccttaaagaa
     5941 tttgctgaaa aaagtctgct caaaccttgg gatgttttta ttattttgct tttgactgtt
     6001 ctttcttttt taccagtcat gatttttggt cttcagcaaa acaccgcaac agcagaaaaa
     6061 gaagcggtac tgcgtgtgga tggcacagaa atcaaaacat tccctttgat ggctggagaa
     6121 gagagcaaca catatactta caaagatgaa cacggagatt ataacttgat cgagatagat
     6181 ggcgatcgag tacggataaa agaagcagat tgcgatgacc agatctgcgt acgtcgaggc
     6241 tgggcaacga aaaatggcga aaccatcgtc tgtttgccac ataaattagt gatcgaagtc
     6301 cgttcaacag atggaggtga cgaagacagt ctgatttatt agaccttcac acaccatgag
     6361 taaattacaa aaaatgattt atatttcgct acttgttgca caaggagtga tcattggttt
     6421 attggaaaat atgatccctt atcctttttc ttttgcgcct ggtgcaaaac taggcttagc
     6481 caatctaatc acgatcgttg ccatttttac catgaaaaaa caagacagct tcttactact
     6541 ttggctacga ctattcctga ctactttgct aggcggaacg atttccacat tcctttatag
     6601 tatgagtggt gctttgctta gttattttgg aatgttattg gtcaagcaat taggaccaaa
     6661 acgtgtcagt atcatcggaa ttagtgcggc cggcggtttc atgcataatg tcggacagct
     6721 tttgatggct tctttcattg cacaatcatg gacagtcatg ttgtacttgc cagtcctttc
     6781 agttttaggg attttatcag ggattgcaat cgggatcgca gcgaattatc ttttacgaca
     6841 tgtgcagaca cttcaacgat tccaaaaaga ttatgagcag ggaaccaaac aaaaatggag
     6901 cccaatgttt accaaaaaat aatcgtcaca caaggagttt ttttatgaag ctacatccaa
     6961 tgtgggaaaa ctatcctgct ttaagtaaag aattgacaga aacactaaaa cggatggaag
     7021 aaactgtccg cctgaaaaac aaacctgtcg aacaagccat caaagaaacg atccatgccg
     7081 gcggaaagct gttgcgtcct gcctatcagc tattgttctc acaatttgga ccagagcaag
     7141 atcgagacaa agccatcgct ttggcagctt ctatcgaaat gctccatacg gccacactga
     7201 tccatgatga tatcgttgat gaagcggatc tgcgacgtgg tcagcctaat atccgtagtc
     7261 agtttggtaa tgtcgtttct gtctatgcag gagactattt atttgtctgc tgttttaaac
     7321 tattgtctga ttactccact tccttgaaaa gtctccaatt gaattctcgc agtatggaaa
     7381 aagtattgaa tggcgaatta gggcagatgg atgatcgcta taattatgaa ctttctgtaa
     7441 aagaatattt ggaaaatatt tcaggtaaga cagctgaact gttccaatta agttgttctg
     7501 ttggcgcttt tgaaagtgga acaagcgagc gcttcgcaaa aaaagcagga gatatcggac
     7561 tttctatcgg gatggccttt cagattatcg atgatatttt agattataca aaagagagcc
     7621 aggaaatcgg caaacctgta ctagaagaca tgcgtcaagg ggtctattct ttaccgttga
     7681 tctactcttt gcaaaaaaac aaaccaaagc tactacctta tttagagaag aaagcggcaa
     7741 tgacagaaga agatgtcgac gccgtacgca aaatcgttga acatacagga ggcgtggaag
     7801 aagctaggaa gttagcggcc tcttacacag aaaaggcttt gaaggaaata aagaaattac
     7861 ctgccacctc tcttcgaaca aaagagaatc tcttttccct tacccaactg attttggatc
     7921 gcaaagactg aatagggaaa ggttcgatac gtaaataaat ttctcagaag gaaatctacg
     7981 tgttttttga caaattgaat tgtagttctt gtatttatga taaaaagcaa aaataaagag
     8041 caacgtccgt tagcgacgtt gctctttttt atcttgaata tttttttacc ttttcgattt
     8101 cttataactc ataaaagtga ttcttaaacc gattacaagt aatataacgc ctgcgagtgt
     8161 tatccaatta ttcgattgac ttccagtttt aggaagtgct ctttttgatt tgtttccatt
     8221 gtcattgctt gttttattag ttaagttaaa gttcgtcctg ttatccgaac ttgtttttga
     8281 gaaggagaca cttgcatgac gtgtatcgct tgtggtagac gacgtgtctg tactatcgct
     8341 tgaagttgat gaatctgagc tatcacttgt ggtagaggat gtatctgtac tgtcacttga
     8401 agctgacgtg tccgtgctat cacttgtagt ggtagatgaa tctgagctat cacttgtggt
     8461 agaggtagta tctgtactgt cacttgaagc tgacgtgtcc gtgctatcac ttgttgtggt
     8521 agatgtatcc gtactgtcgc ttgaagctga cgtgtccgtg ct
//
LOCUS       DACGMI010000092         8543 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.095, whole genome shotgun sequence.
ACCESSION   DACGMI010000092 DACGMI010000000
VERSION     DACGMI010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8543
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.095"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..888
                     /locus_tag="IXT46_002694"
     CDS             <1..888
                     /locus_tag="IXT46_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAQ4948579.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
     gene            complement(928..1620)
                     /locus_tag="IXT46_002695"
     CDS             complement(928..1620)
                     /locus_tag="IXT46_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4948580.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            1705..1881
                     /locus_tag="IXT46_002696"
                     /pseudo
     CDS             1705..1881
                     /locus_tag="IXT46_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(2057..2626)
                     /locus_tag="IXT46_002697"
     CDS             complement(2057..2626)
                     /locus_tag="IXT46_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4948581.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(2700..3023)
                     /locus_tag="IXT46_002698"
     CDS             complement(2700..3023)
                     /locus_tag="IXT46_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948582.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(3177..3989)
                     /locus_tag="IXT46_002699"
     CDS             complement(3177..3989)
                     /locus_tag="IXT46_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948583.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            4343..5191
                     /locus_tag="IXT46_002700"
     CDS             4343..5191
                     /locus_tag="IXT46_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAQ4948584.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            5336..6277
                     /locus_tag="IXT46_002701"
     CDS             5336..6277
                     /locus_tag="IXT46_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAQ4948585.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            6267..8438
                     /locus_tag="IXT46_002702"
                     /pseudo
     CDS             6267..8438
                     /locus_tag="IXT46_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2664 a         1632 c         1521 g         2726 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt caacttttgg
      901 ggttcagttc aaagaggggg ggatttttta tcgttgtgga atatttaaat accaacgctt
      961 gtcatgaaaa tcttgtgctc cacccttagt atttccttct ggatcgtttg tcgcacgcat
     1021 catgacgtat actttcttat tagggaaatc acgcatattg aaagatacat gatagccaac
     1081 atttcctaaa gtattataag cttgatttac gtctggtcta taaatcccat cagctcttac
     1141 tctagctagt tcttttccag tattgtagtc cataatgaaa atatactcgt atttataatt
     1201 agcaatgtgc catccagcta catgcaagtt tgcgttttcg atttctccga actgatcaat
     1261 gtgggcgtaa tttgttccat ctgtcagcgt agaatttgca gcacctgctc gagttggatc
     1321 aattactggt ttatcctccg aagtagttgg attatcatcc gtaaaaccat gagccaaatc
     1381 ataggctagt ttttctttac ttacacctat ttcagaaaga taaccgtaag gatctgtatg
     1441 atcgccccaa atattttgtg ttacccataa atgcgatttg attcctggtt ggttataagg
     1501 agtgtctaat gttaatggaa taccatattt cattgctgaa tctcttgcca attcaacgta
     1561 tactttatag ttcttttcaa aagtttcttt atcatgtgtg tgttgtaact cgatttgcac
     1621 aggacttttg gctcacgagg ttgtcctact ctacatcttg ctgatagata tgctgaaagg
     1681 aaaacaccaa cattatgttt tgctttttca gctagaacga gacaagcagg aataccttta
     1741 gaagatatca aaggtttttt aggtcataaa gatgtttcca ctacacaagt ctatgcccat
     1801 atttctcccg aagtgaaaaa aagatcaatg aatcaactag aaaactatat agaagagcaa
     1861 ataaaaaagc actcaaattg agtgcttttt taagctcact atcactaaaa ctatcactaa
     1921 ttttatttat aagcgaacat gtttctatca ctgatttttt aaatctagcg aaaaaccctt
     1981 atcttaaagg cgttcgttca attctttggc aaggtcttca aagcctggct tgcctagaag
     2041 tgcgaacatg gttttcttat agctcatgta gaaaaatttt cttgatgatg attttatcca
     2101 tcaattgaga ttgactgttt tgctctccta tgatttcagc tatgattgtc cgattttgcg
     2161 gttttcttct taactggtag ttgattttcc cagtttccat caactcgcta agcatatcca
     2221 cgactccgcc aaatccggtc tttttcgtaa taaaacctag tgctaccatt cgttcatcta
     2281 gattttttgc tgtaatcgtc acaccagtaa tgagcgagtg ctgtaatgtt tgggccagct
     2341 cttccatccc ttcagcattg gatacgacgg aagctgtttt gttaataggt tcttcgttta
     2401 tttcttttgg ttctttcctc tccactttca ctgtttgacg aaggacatct agttcttgca
     2461 agagcgtttc gtattgttct tgggtcagca tcacgccagc tactttttca cgattaaata
     2521 tatatacgcc agttcccgcg tctcgcgctt gagcaaatac atccatcggc gatcgtttca
     2581 cttctgtgat cgaagatgtg ggaacttcta atttctttaa ttccaatgga tttcctcctt
     2641 tactaatcgc tttttattat agcacagact gacttgtttt gatctttttt ccaaaggttt
     2701 tatcggtttt tgcctaacca gtaattgata tcggtaagaa gtctttcgat accaaatgaa
     2761 ggatggtaca gatacgtttt ttgatcttcg ttatggtcta gtggaaaaaa atgatcgatg
     2821 atcactagat ctgcataccg aggcggctta tttcgagtac atacatgtat agagatccgt
     2881 tttcgatgtc ttagcgtttt gttcagtacc ccagcaagtc ttcttgcttc ttggtgttca
     2941 tagcgaaaaa aaaagacgat tttcacttca ggagggtgga catctaaata ccctcgttcc
     3001 tggagtgttt tcagtaaaag catcccccac tctactgcgg ggtgtgcaag tgcttgttgg
     3061 atcgctagcc gaaattgata tagtttatct ttggaattgg gaaatttttc taatgtttcc
     3121 tgataataac gaacttcttc tatcagccgg tcatggatac caattacgta acgaagtcat
     3181 tcttggtaaa gtacttttgt cagctttgat ttgctttcgc tctcaaattc gctattcagc
     3241 caaaacagcg aatcaagctt ttcagtcaca atcgtcaatt tccgatagtc ttgtgtctct
     3301 tctatccgtt tccaccgctt ttcagtaatc tggttacagc tcaagcgcaa aattgctaga
     3361 taattttttt cttttattgg caaaatctgc tcctctctaa atagcaattc aggaaacaat
     3421 tcaaagaata gtgttcgact gtctcctaaa atctcgattt ctgccggatc ctttctttgc
     3481 ttcaataatt ggatgaacat ctcagaaaag gactgctctc catcatctgc aaaaaaatgc
     3541 ggaaaatctt tcaaaaagca aaacagcaga tatcttactt ttctttctga accaaagatc
     3601 tgtgcttttt tataagaaaa agaaaggtgg tactcgccaa accactttct caatcgctct
     3661 tgcgtagaac gatcgtactt ctgctcgtaa ggttcattca atagcagatt tttcagtaaa
     3721 caaaacgggg gtgattggat cagaaaaaca aacaagagat aaggttcgct atatccttga
     3781 tcataaacta actgaacggt tttcttatga agaatcagct gaatgggaca gtcgctttcc
     3841 gccaaacgtt tcagatgccg atccactgtt ttaacatcga ttttcagttc ttcagctaaa
     3901 tcagcttttc gccagatcaa atctttcatt agattgatta gtgaaaataa attctgtgca
     3961 ttttttgata atagtttttg ccatctcatc gatcatttct cacctgattt ctaaacatat
     4021 tgtttgatca aaatgggttc actcctaaaa agataaaaaa ctccctttct atttatttaa
     4081 atacgcaaat cttcctcatt attttttatt ttactcaatt taatcgtatt ctcatttcaa
     4141 aacgaatgta ctttaaaaaa acataataag atcactttgc ttgtaggatg tattcccttc
     4201 cattacaatg aaataaatag cgattttatg agaaggtgat gtgaaaatgg aagaaaaaat
     4261 agaagaatcc aaacaaaaaa tcgatcagtt gatataagaa ttagaaaaag cggtcatcgg
     4321 caaacgttca actatccaat tgatgatcgt ggccctatta gcaggtggtc atgtcttatt
     4381 cgaagatatt cccggtgtag gtaaaacgtt actggtcaaa gcactagcaa aagctgtaca
     4441 gggaaccttc agcagagtcc aatgtactcc tgatctgctg cctagtgata ttcttggttt
     4501 ttccgtatac aattcacaat caaaagagtt tgaatttcgt ccgggaccga tctttaccac
     4561 gatcttgtta gcagatgaga tcaatcgtac gactcctcgt actcagtcag cacttttaga
     4621 agcaatggcc gagaatcatg caacgatcga caacaataca taccctctag acaatcattt
     4681 ttttgtctta gctacgcaaa atccaatcga gtacgaagga acatatcctt tgccggaagc
     4741 acagctcgat cgttttttat tccgactaca aatcggttat ccttcttttg atgacgaact
     4801 tttgctactt ttggataaat tcgaaaaagt gttggataac ttaaatgaag tattgaacag
     4861 ttatgaaata gaagaaataa aaacaaatgt ggcgaatgtc tttgtcagtc ccgaagtggc
     4921 atcttatgcc ttgcagttag tgtcagcaac aagaagtcat gctgccatcc agcttggcat
     4981 cagtccacga ggaagccttt cctttattca ggcagcaaaa gcttatgctt taatccatgg
     5041 gagaaattac gtcacgccca aagatttgca ggatttagtt ccttacgtgt tttcccatcg
     5101 cctgattttt tacgatcgtt cattgaagga agacgaaaag aaacaaatca ttcatactct
     5161 tgttgcacaa attcctattc ctgtgaggta gattgaggta gacaatggaa aaaatcaaag
     5221 attatttcat taattttgtg ttatttctgg tatatttcat cattgtgctt tttgctcttg
     5281 tattcaacaa ttctttaggc tggttcttgt tggccttttt tactctttat gtatcatgga
     5341 gcttgatttc attaagcagc tttctaaaga aactttcggt tacttgtaca ttgcagccac
     5401 tcgtttatcg caaaaaaagt atgcaggtta ttttttccat agcaaaaaag agaacttttt
     5461 ctttacctct ccctcgttta caaatcggct tcccagcaat ctttgcagaa aaaaacaaga
     5521 gattttgatt cttacaaata aaccgcaaga agtccaattg ctttggcagc caaaagaaag
     5581 aggatgccat gaaacattaa ctgtcatttt tacagcctat gatagtctag gacttttcag
     5641 aaaaagtgca aaaagagaga tctcttttcc tgtgactgtt ctgcctgctt tttgtaagat
     5701 tcaagcagaa aaattacaga gagttctgga aaaaaaacag cagctgaacg cgtaccaaag
     5761 aggtcttgat tttcgggaac atcgcgctta tcgtccaggt gattctttca accgaatcga
     5821 ttggaaattg tctgctcata ctcaagagtg gttataccgt gaatacgatt atcaagaaga
     5881 agaatgttct cctctttttt gcttttgggg ttcgcccagt ccaaaatttg aacctctgct
     5941 agacttgtat ttttctttat ggcatttgag aaaagaaaag cagccggaac ttctgatatt
     6001 aggcaaccgc gcctttcatg gcaaagaccc cggtcatacc tattttgctt ctttggaagc
     6061 tggcgatgag aaaacttttt tcgcacactt gaaaaaatat gcaaaaaaac aaatcgtcct
     6121 ctttgttcct gagaattctc ctgaagtctc agaagctatt gaaacattgt caaaagatcg
     6181 aacggtttat cttgtttatt tcgtagaaaa acaactcatg gtccaagaaa aagacaagat
     6241 atgttcattg ccaggaggtg aatggattga cgattaaacg ggaaaaatgg ctgcgtggcg
     6301 tttactcctt tgtgatacta agtgtaggtg ctccgatatt tgtagtagct aatcaattgc
     6361 aaaacagcta ccttcttatc ctaactattg gtgtcctatg ccttattgtc tgctgtattc
     6421 ctaaaaaatg ggtacgtttg ctgctttctt tgccagtaat gataggttgt ttgtttttat
     6481 attttccttc gaagacattt tccatattat ggatcttaca gtttttttcg tcagttacag
     6541 aggaattctt ccatctatcc caaggtaaac tttattattt gccagaaaag acagcttttt
     6601 ttctcataat gttgctgatc tatttattta ttacattgac cgtggattac gactattggt
     6661 acgcaccctt tctttctttg atggcttact tcatgatgct taccgttttt cggaaaaaag
     6721 atttactgta cgaaatgatt gcggtagtaa ctgttttgtt cgtgtatctg gcagcaaggc
     6781 aatttttctc catccggttg ttgtcgagaa acactcgatt ccagtcattg actacagttc
     6841 tgcttatttg tttcttaact tttagcgcta tcttgccttt atatcttccg aaagtacacc
     6901 aatctctcga ggaaacgagt gaaccgatcc gagaatatct taatgatgaa gggctttatg
     6961 acacactcca tgagtatcaa ttaaccggaa gtgcaagaac aggcttcagt gagaatgatg
     7021 aacagcttgg tggaccttta tatgataatg gcgaagttgt ttttacagcg aaccaaaaag
     7081 gaaatggcta ttggaagatc gaaaataaaa atcattacac cggttctgga tgaatagaag
     7141 atcaggacgc acccatccaa ccaatccaag aattccctgt tgacatcacg agctaccaaa
     7201 ccgttataga agacaaagaa aacattacat tgaccctaaa aaaacaagct ttcttacctt
     7261 atccttatgg aaatactacc ttgactgatt tttcattagc tagtggacaa acgctttact
     7321 atttgcctga aagccagcga ttcattcctg tcccgaatga atcgacacgt tctgcaactt
     7381 tacaaacaga aaggttagtt tttacgagag aagaattaaa aagcagtcag ttaaaagctg
     7441 atgatttaga aaatcagcag acaaatcttc aattgccaaa aagtttgcct aaacgtattg
     7501 aggacttggc ggtcgaattg accaaaaatg aagcaacttt aattcgtaaa gtcgaagctg
     7561 tctaacagta tttaaaaaca agcggaaatt tccgctattc caaaacggat accgggcata
     7621 ctccaaaaga acacgattat gtggattatt tcctctttga ttcaaaagtc ggctattgtg
     7681 acaacttttc aacttctatg gtcgtccttc ttcgaacact tggtatccca gctcgctgga
     7741 caaaaggttt tacaaatggg ctcagaacag gcacagataa tcaagggaat gaggaataca
     7801 gcattctcaa tagtcatgct cattcttggc cagaggtata ctttcctgga tttggctggc
     7861 ttccatttga accaacccct tcatttgcca atccaatggg ttcacaacca gttgctgaaa
     7921 caaccgaaac cgtccagcct gctatcgaac aaccaaatga aagcgaaaat atggcagaaa
     7981 ctatttccag tgagagatct gaggtcattc catcagaaga aacaacactc acaccagctt
     8041 ataaaatcgt cttattcagc cttggagtgt gtttatccgt cttgttgttc tttctattgt
     8101 tattcagaaa atctctgcgc tggacaagtt atcttatcta tcttcatttt tttgcttcta
     8161 ctaatacgat tgcatatcaa aaacttctta accctttgga aacattggta ccgcgcaaac
     8221 ccgcagaatc tttgcaggaa tatagcctgc gaatagaaca agaattcaag ctagatctgc
     8281 gtttcattcg attaactact caatatgaag cagaaatata tggacgacaa gcagatccgg
     8341 taaaattcga taaaaaaacc tatttagaaa taacgcatat aataagaaaa acggtataca
     8401 aaaaaattct gacaaaaggg agccgcttca aaaaataaga taaaatttct ggagaatcta
     8461 cttctcgaat gccgagaacc agctgattga gtatcgatta ctcgaaaaaa aggttgtgac
     8521 acgttttttg tcacaacctt ttt
//
LOCUS       DACGMI010000093         8228 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.096, whole genome shotgun sequence.
ACCESSION   DACGMI010000093 DACGMI010000000
VERSION     DACGMI010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8228
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.096"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="IXT46_002703"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="IXT46_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAQ4948586.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="IXT46_002704"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="IXT46_002704"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAQ4948587.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="IXT46_002705"
     CDS             2591..3376
                     /locus_tag="IXT46_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4948588.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="IXT46_002706"
     CDS             3389..4240
                     /locus_tag="IXT46_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAQ4948589.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="IXT46_002707"
     CDS             complement(4364..4816)
                     /locus_tag="IXT46_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4948590.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="IXT46_002708"
     CDS             complement(5281..5649)
                     /locus_tag="IXT46_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAQ4948591.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="IXT46_002709"
     CDS             5799..6281
                     /locus_tag="IXT46_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAQ4948592.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="IXT46_002710"
     CDS             6318..7328
                     /locus_tag="IXT46_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAQ4948593.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="IXT46_002711"
     CDS             complement(7443..8156)
                     /locus_tag="IXT46_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948594.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2784 a         1337 c         1667 g         2440 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtc
//
LOCUS       DACGMI010000094         7960 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.097, whole genome shotgun sequence.
ACCESSION   DACGMI010000094 DACGMI010000000
VERSION     DACGMI010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7960
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.097"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..1594)
                     /locus_tag="IXT46_002712"
     CDS             complement(<1..1594)
                     /locus_tag="IXT46_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948595.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMNLT"
     gene            complement(1614..1781)
                     /locus_tag="IXT46_002713"
     CDS             complement(1614..1781)
                     /locus_tag="IXT46_002713"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948596.1"
                     /translation="MVNEVETLLASFFENGHVNDEWRKEEPKRVNAYIARLKRFIDKY
                     KENSDKFSKDK"
     gene            complement(1818..2507)
                     /locus_tag="IXT46_002714"
     CDS             complement(1818..2507)
                     /locus_tag="IXT46_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HAQ4948597.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            complement(2762..3082)
                     /locus_tag="IXT46_002715"
     CDS             complement(2762..3082)
                     /locus_tag="IXT46_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948598.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            complement(3115..4233)
                     /locus_tag="IXT46_002716"
     CDS             complement(3115..4233)
                     /locus_tag="IXT46_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948599.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLRTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            complement(4262..5056)
                     /locus_tag="IXT46_002717"
     CDS             complement(4262..5056)
                     /locus_tag="IXT46_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948600.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            complement(5066..5941)
                     /locus_tag="IXT46_002718"
     CDS             complement(5066..5941)
                     /locus_tag="IXT46_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948601.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKED
                     ITKMKPVIKILDNKE"
     gene            complement(6158..6415)
                     /locus_tag="IXT46_002719"
     CDS             complement(6158..6415)
                     /locus_tag="IXT46_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948602.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            complement(6418..6642)
                     /locus_tag="IXT46_002720"
     CDS             complement(6418..6642)
                     /locus_tag="IXT46_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948603.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            complement(6815..7858)
                     /locus_tag="IXT46_002721"
     CDS             complement(6815..7858)
                     /locus_tag="IXT46_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyhydrolase"
                     /protein_id="HAQ4948604.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
BASE COUNT         2234 a         1642 c          998 g         3086 t
ORIGIN      
        1 ttgttaagtt catattcaca tgattatcca aataaaatat cttatcttta ttagaaattt
       61 cactcataac acgataatat agaccatgat tcaagtaatc tgtatataga aaaatcgcat
      121 cacacgtatt caaattttta agtatctttc cattattttc gcttacatca aacattttaa
      181 tatttggtaa tagttcagtt aatttatttt gaaaatttac atgtcctccc actaaaagaa
      241 tgtttttatg ttttagataa gctatcattt cagacagtga aggctcttca gttttaccat
      301 ttaatgattg tctatgttct tgctcctgca attgctttaa tactttattt tcaaacctca
      361 gctgttcaag ttcttttctg attcctttta attctttaat ctcttgcttc aaaagttcct
      421 cttctttttt tgccgatttg actaaagatt ctaaccgacc gttttcttta ctcgcaatac
      481 ttaattcttt tcttaatttg attacttcag atttgttttc ttttctaata cttgcaattt
      541 gttttgctat ttcataatca gaattcagga tcaattcttc cttagcattt ttaaacaacc
      601 gagttaaaac gaactgatat aacaaactat aaaaaactag caaatagtca atttgtcggt
      661 actcggtatt ctgatcaatt gcatatagag agattaaaac gaaatacaca atatcattca
      721 gctcgctacc cttgatctca aaattattga ctaagtaact atcaataccc atcaaatctg
      781 caaaatctcc atacaaagaa aaatatgatt ttgacaatat atctatatct gaatcgtcaa
      841 acccatttac tattttccca tcattgttag tagttgctaa cgaagcaata gtgacttttg
      901 aattgggttt tacaaatcct atacctaata gttctttcat ctttttaatt tcaagtttgt
      961 tatccttttg ttcggcttta tgctgtttca tattgtaaag cggataaaat gctgttccgt
     1021 aagcaccttt tagtacgtta tctataaaat aatcttcaga acctgttttg aatagaaagt
     1081 taatcgcagc caaattagat aacagctctt cagtgttgtg catcaatttt ttatcattta
     1141 ataaattatc cccaagatat ttcattgcat aataagggtt tgtttcgcta cttattttta
     1201 atattttttg atagctattc ctcacgatat taaccaaaat atctgtctga ttaattgaat
     1261 tacagtacaa agccactcct aatgccatat aaacattcaa atcatgtttt gccgtaccgt
     1321 tgaataaaac gtcttcaact tttgaattat ctcgtctata ctttttgatc atatttttga
     1381 tattttgatc attctcttgg tatatttttt tcactcgttc caatgccttg ggtttgttgg
     1441 aaacagcaac agcgaagtct agttctttga aatcaatatt tagtatctgt acctcatcac
     1501 ctagattata atctctattt acgctcggaa aactgctgaa atctaactgt tttttaccta
     1561 tttttggcga aaatattcct tcgatttctg gcaaatgtaa tcacactctc tccttattta
     1621 tctttagaaa atttgtcact attctcctta tatttatcaa taaacctttt taatcgagca
     1681 atataagcgt taaccctttt aggttcttct tttcgccatt catcgtttac gtgaccattt
     1741 tcaaagaaag aagctaaaag agtttccact tcattaacca tatctgcgat cgtatatttt
     1801 tctgtaccct cactcaatta ttcatgaact gttaagtgtt catagctaag ttcattcata
     1861 attttgttat agcgttttct tgctttttca aattctttct gttcgtcaaa ttccacttga
     1921 ttcttcatgt tgttcttcct ctctgtttga tattttttca cttcttcaag tttagcatct
     1981 agttccgctt taacttctgt cacttcttta agcgcttggg ataacttatg agacaatttc
     2041 gcataagttt ctctcttgta ttcatttcct actcccaact cttcggagta gaactcttct
     2101 agtagtcttg caaaattaac atttctcctg ccagcatagt tttttagctt ctcaaaatca
     2161 gattgaaaga cagcaacact tttgtaatcc ttttcaccct caaaatcaaa agcatagtca
     2221 tactttcctg aaatcaattc atcaataact gtagcaatat attgagagat agaaatatta
     2281 tcttcacttc tatgtcgctc tataagatta tatatatcag ggctgacatg aaacgtactt
     2341 ctcttttttg tttgcctttt tctaactgtt acgaccactt ttggaacttc actatctcca
     2401 ttgatctctt tgtatttttc aataaataat tttctagctt gttctcgact ttttgccgga
     2461 atttcatcta caattttatc ttctaaataa atatagtgtg ttctcataca ttcgtcctct
     2521 atcttcttta ctctcaatct tcatgatctt agttcttacc ttgtttactc ttaaacattg
     2581 caaaaaaatc tagtcaaaat caaacttgaa atcatcgtct atcacaacac ccttaacttc
     2641 atctttagat ttcccaaagg aacccttatt ttcaaatcct ttatttttga atgatgatgg
     2701 ttatggaaaa cttcctttga aattctgaca agcataacta gtcagaactg ttttacttag
     2761 attaagcttt caaaagatac tgatgaagaa ctaagttctc agtaccttcc cattcttcaa
     2821 taaaaaatat ttctccttct tttacccact ctatagctaa tttcttataa tcaaataaac
     2881 catatgtgtt taagcctttg tctttcatta aactcaaaaa ctgatcccct tttaatcttt
     2941 ctgtatcatc catcagaaat tcaactaaat ctttatccat gcgtgcaact ttttcgtctt
     3001 ttagtgccat tgatttagca tagtcagttg aatcttttag aataataaca cctacatttc
     3061 cttccacaat tttcttcttc atatttacct cctaccatct tttccaaaga gtatttagtc
     3121 aaaatcaaac tcgaaatcat cgtctatcac aacaccctta acttcatctt tagatttccc
     3181 aaaggagccc ttattttcaa atcctttgtt tttaaattct aaagcttttt cgacttcttc
     3241 tttggatatt gtatgaactt ttttcttaac tactccaagt ttatacagct cttcaaactc
     3301 tggtacttcg gatctgaaat acaatccatc agtacgaatt tttaatagcc catatgcgct
     3361 atgaacgtat ttctgttcat atctaaccat acgatctcta aatacgcctg ctaccatgga
     3421 ggaatacgct cgattataca tactgtattt atcgaaggtg cttgtttctc cttctcttaa
     3481 tgatttttgt ccgatagcac caaatacttt cgttctaaga tttttataaa gcttcaacgt
     3541 atcaggatca gtttttaatg gctcgattct ttcaaaatat tctttgagta atcctttttt
     3601 cgtcaaaaat gtgtggctat ctaggacttc catctcttta atatcataat aatcaaggat
     3661 aagtgttagc tcaatctccg ataaccaaat aggctcatta gctgttttgg gattttcgcc
     3721 ataatccgca aacatcgact gtgattttgg attagcatat gttccttctt tggctgttcc
     3781 ttcaaaatta accaaaaaga acatatacgt tcttaaattt tcatacggtc ttacttttgg
     3841 tctatttatc gctctcaaaa tagcttgatc tgtattatat tttgctttca aataagtgtt
     3901 tgacggcaaa ggataatttc tcatgatcct cgaataggct tcgttgaaat catattcgat
     3961 catctttgct ccttcctcaa acaaatccaa gttatacatg ctaccggagg tactggctct
     4021 ataggctgaa cttggaacaa agaaaggtgc atcttccggc ttatcatagc ccaaaaaatg
     4081 tattcctgtt tgcttgttct gacggtaaat gtccatcaaa agatatttga tcgtactaaa
     4141 agaatctaat tttcctcttg tcatccaccc taatccgaca agtcttttaa ttttattctg
     4201 catttcaggt gtgtatatgc tattgtttcc catttatctg ctcatctccg gcttttttat
     4261 tctagaccct atatttgttc attacaccac ttatctcgtc tacaaaggct cccagatcgt
     4321 gtgtaaaggc atcatagtaa tcttcaatct cactcgattc agttctccgg tttcttccgt
     4381 ttttatttct gaatagatac atctgcgttt ctcttaaatc ccttgctttt ttcgcaagtg
     4441 ctaataaatc cgtaaaatta tcaataacca taatgtcatt gatcataaaa ccttcttcat
     4501 gaccatactt ttcagccatc tcgataaaat cattaacatc gaacaactcc aataattctg
     4561 ctttatattt ctctaacaat gtatttaaat agcgatttct caattcccat gaactttcac
     4621 cagttccgta ttcaaccttg atccctaaat tcttagtgta gccttttgct gtgtatcgtc
     4681 caatgaagtc tcccttattc cgattgctat cttcttcttt gaaaaactca cgccaaatcc
     4741 cctttttctt cttaggaatt agacctctgc tcttgaaatc atcatatttt tttgaagctt
     4801 ctcttcgtgt atctaagtac ctttgcttca gctctgtagc tgattcattc gttccatatt
     4861 caacagtgat ccttaagcgc ctgctataac cttttgctgt atatcgtcca acaaagtcac
     4921 cgccacttcg atcactactg acttccttaa caaattctct ccatatacct tttttgtcct
     4981 ttggtattaa tcctcgtctt ttcatatctt gatatttttc agaagcttct tttagagtat
     5041 tcttttttgc taccatattt tccactcact ctttgttatc tagtatttta ataactggtt
     5101 tcatttttgt aatatcttct ttttcagcta tatacaactc cgttacggta acgatcttag
     5161 tatgatttag attaattact ttcacttgat cgccaatttt gatttttcct cgcaaccgtt
     5221 tgggaataaa ccagttgtat aatcgtgatt tattattatc tacataagct tttattgcat
     5281 tttcaggaaa caggttattt agtctttcaa tttttttact tttaaaaaat tcattcgcaa
     5341 acttttcatc aacaactaaa ttaaataaag tttcagaatt tacagcttcc atatctattc
     5401 ctttgtagat aggagaaagc aattttttat attttgccag taatgacttt ccagaattac
     5461 taatcttaat ttggttactt aaatcttctt gataaagaac cccatatcga agtaacgcct
     5521 taatataatg ttttaatatg ccgttgatac cagaataaat atccatgccg ttctcaatat
     5581 agtagaaagt gtcgtctctc caaaacaatt tgaagctatt attcaaataa agtaacaaga
     5641 tcaatatatg tttgtcagaa attctgacaa atctattact ttttagatac tcaccaatgg
     5701 cttcacttaa ctctttgaag ccattgtatt ttcccgataa aaatgtcgta acattatctt
     5761 ctctcttttt cctatggtgt gaacttaccc tgaaataata gagtctattc tcatttaata
     5821 ttgaaaaata aatactttca gttgtttgtg agcattgtat atagttgaaa tgatatccat
     5881 ctggcatgac ttttttaact gtattttgta ctagctctga ccaccttttg ttagtagtca
     5941 tatatttttt tccattaaac caaacataaa tatctttttt aaaaattttg ttccccccct
     6001 attgcgtttt ctttgacatt aaagcccttt gttttcatca cattcgtata gccctagcca
     6061 ctcataacct gatgcttttg cgaagtttat ttaaaagtgt tttcctttgt aatctacctt
     6121 tcccctcgtc ctggtacttt tcttggcgac tattaaacta ttcaactttt ttagaatcat
     6181 tgtcagcttg aaatccttca cgtttcatta tgtcttctgc ttttccaatg ctgattcctt
     6241 tccaatcacg ccatcctacg cttcccttat tttgacgata ggctttaata gctgattcgg
     6301 atatttgcca tcttgtagcc aactctttgg ctgtgtactt atttgaaaaa agtagcttct
     6361 ctatcagtga aatatcaatc attttattct cactcctgaa atcttcatta atcatctcta
     6421 gctagctata tcttcaatca attctaatat gtcggataaa ccatcaacag cttcttcaag
     6481 ttgatcaacg gattcttctg ctttttcata tctttctgat ccctgtagat ttttaggtat
     6541 attttctttg tactcttctt cttgaattac ttctaactca tcctttagct cggaaagtcg
     6601 ctcgcttatt tcttctaacc tttttcttct tctttggttc atcaaaatca cctcttcgca
     6661 taatctctac gattttaata taccactttt gtgtactaca ttcaatattt tttgttatag
     6721 attcgtatta caaaaatttc ctctaaaaaa ataagagcct atttaccatt tcagtaatta
     6781 agctcttatt tcatttagtt gataattcta tcaattaacg tacagcaacc gccattccag
     6841 tcacattaaa tgctctctca tacgtgcttg cattgatcca ttttgcgcca aatacagggt
     6901 caacaacatg gtatgcacca tttctgaagc catccacgag aactacatgt ccattccata
     6961 ctgcacgacc ccaaggcatt tgtttgaact ctggcgtagc atagttataa gtaatccaag
     7021 ttacaaccgg attaccattg cgaatttcat tcttgattcc attcgttcct gaaccagtga
     7081 tattgacggc attaccgcca acgttttttg cccatttaac tactgggtca gccatcatgc
     7141 cttgatacgt tccattaacg ttatgacgcc actctcctga gtaaccatga taaggattat
     7201 tgtcattagc ttttggcata tagtttacaa aactggttaa gctttgattt gtggctacac
     7261 ctttgtagtg taaaccttct aataaagaag ctccttcgca taacattgta tttccttgcc
     7321 atacaacagg aacgttcaac actttttcag tgcttggagc aggtgtagga tttggtacgc
     7381 tgtttggcat tgcataccag cctgtacctt caatcttcca accttgttta ctaattacgt
     7441 tcttttcatt ttgatctaac gtgtagtgat gccaattcac gtatttgtta tataaacgtg
     7501 ttacaggaac tctatttgct ccgttgtagg aatagaacgc aacaccttcg tacgtccatc
     7561 ctgtgtgtga aatcttatct ctttctccgg catcaactgt gtaaaaatgt tcaccgttat
     7621 accgattata caaacgataa acaggagtac cacttgttgg agcttgccat gcgacacctt
     7681 cgtaatgcca tccataacgt ttcagattgt ctctttctcc aacgcttcta gtgtatagat
     7741 gctctccgct attgggatta tacatacgat acatggaaat agagctttct gctgaaactg
     7801 aaggtgataa taatactagc cccattgtga atagaattcc tactaaaaat tttttcattt
     7861 gattttaccc cttttcattt tttattgtca ttattgcatg aaaattattc gtaagattgc
     7921 caattacata aacgattgtt ttaagatcat aatcgttgtt
//
LOCUS       DACGMI010000095         7838 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.099, whole genome shotgun sequence.
ACCESSION   DACGMI010000095 DACGMI010000000
VERSION     DACGMI010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7838
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.099"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..456
                     /locus_tag="IXT46_002722"
     CDS             <1..456
                     /locus_tag="IXT46_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4948605.1"
                     /translation="TIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQ
                     SVPKNLFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGL
                     PKEMEFNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
     gene            complement(570..1700)
                     /locus_tag="IXT46_002723"
     CDS             complement(570..1700)
                     /locus_tag="IXT46_002723"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAQ4948606.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(2349..3551)
                     /locus_tag="IXT46_002724"
     CDS             complement(2349..3551)
                     /locus_tag="IXT46_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4948607.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3611..3814)
                     /locus_tag="IXT46_002725"
     CDS             complement(3611..3814)
                     /locus_tag="IXT46_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAQ4948608.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3956..5188)
                     /locus_tag="IXT46_002726"
                     /pseudo
     CDS             complement(3956..5188)
                     /locus_tag="IXT46_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            5351..6163
                     /locus_tag="IXT46_002727"
     CDS             5351..6163
                     /locus_tag="IXT46_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4948609.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(7187..7339)
                     /locus_tag="IXT46_002728"
     CDS             complement(7187..7339)
                     /locus_tag="IXT46_002728"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948610.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7530..>7838)
                     /locus_tag="IXT46_002729"
     CDS             complement(7530..>7838)
                     /locus_tag="IXT46_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4948611.1"
                     /translation="LGVKGQNLLADDSFWQIEDFYLAQCAYNTTLMFSPDRIIFGGGV
                     MKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGIIGGLALARKAVRNKQP
                     "
BASE COUNT         2436 a         1574 c         1210 g         2618 t
ORIGIN      
        1 acgattgtcg gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa
       61 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
      121 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      181 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      241 ccaggaacgc cttcccaacg gggattaaat gaacattcaa acggactcct ccgaaaagat
      301 ggactaccaa aagaaatgga attcaaccaa gtcaatcaag gattcatctc atccgttgcg
      361 tccaaaagaa accatatccc tagaaaatca ctaaattacc aaacaccatt agaagttttt
      421 ttgagttacg taaatggaaa gttttgtctc gcttaatttg acaaataata caaataaata
      481 atataaaagg taaataaaaa agagtggatt tctccactcc atgaaaagcc gactttttgg
      541 gacgcttttt tttgccaagc ctcacatttt tatagccaaa cttcttttgc gacttgctgc
      601 aataattgga ttttcttcca ttgttcttct tctgttaaat ggtttccttc ttctgttgaa
      661 gcaaacccac attgaggact gatacttaga ttttccaatg gtacaaattg ttgtgcttct
      721 tttattcgtt cttttatttt ctccgtatct tccaaatctg gaaacttaga agtaactaat
      781 cctaaaacaa ctttactttc tttgttactc caatgtctta aaggagtaaa atctcctgct
      841 cggtcagaat cgtattccaa aaagaaacca tcataatttg ttgaaaacaa ctcttctgca
      901 atgggttcat atccaccgga aaacagccaa gaagaagcgt gattcccgcg gcagatatgt
      961 gttgtgatcg tcaaatcttc tggtttgtct tccagtgcgt tattgataat ctctgtacaa
     1021 atatgggcca tttctttcgg atcaattcct ttttgaagaa gtgcttctct tttagtttga
     1081 tcagctagaa acgcccaatt tgtatcatcg aattgcaggt aacggcaacc tttttcataa
     1141 aaagcatgaa tcgctgcttt gtaagtagag gacaagtcct cataaaaatc agatagatca
     1201 ggataaatct ccttgatttt tgaagaacca tcattagata ggatctcttg tcgtaaaatc
     1261 atcgtgggac tagggatcgt tgcttttgca acaaaagtat catctgtttc cactacttct
     1321 ttcagaaaag caaaatcttt taaaaatggg tgatttggat tgaaagataa tttatctact
     1381 acccgaatat tataagctgg tgctgctttt ccgtggaatg tttgattata tccagtttct
     1441 ggaacatagc cttcgatacc atttagttct tctaaaaaat caagatgcca aaatccacgc
     1501 cgaaattcac catctgtaat tcctttgatg ccgactgctt tttggtcttc cactaatttt
     1561 tttatttcct ggtcttcgat tgcacgaagt tcttcttttg aaagtaagcc ttcttgaact
     1621 ttttttcttg cttctttgat cgattgcggg cgtaagaaac ttccgacatg atctactgta
     1681 aatggtctat ttttgctcat ttcactcact cttttctttg ttttttgtaa aaaaaaatcc
     1741 ttttactagc aaatactagt aaaaggacga ttatactcgt ggtaccacct tttttcagaa
     1801 aaaacattct ttctctcagc ctgacaataa aatcagtggt cttggtaacg aaagactgtt
     1861 cgtttttgcc tacctttcga caaaaaatcc tctaaggcca ttttcgacag tcaacttcta
     1921 gctttttaca ccaaccaaag cctctcttga accattttct gtctactttc cttctcatcg
     1981 gatactatta gaataaaatt agaatagcat gtttgaaaga aaagtcaata gggaataaga
     2041 acaaacaaaa actaatttgt tattcttagt aatttgtttg tggaatacaa taaagctttt
     2101 ctaatatgat aattgttcag tcgtcctttc atcttagatc acttccttaa aatgatcata
     2161 cccgtttcaa ccacataaaa aaggacttaa ttttgaaaaa tttcccatca aaactaagtc
     2221 ctttttatta tagttatgca aatttgctta ttttctcgct atttccgata catcttgaac
     2281 aggagcaatt cgactgaaaa cactggtgca aaagcattta tttgtcttat ggtagaaccg
     2341 tggaaaactc agactggtaa taaattgtca ttttttgaaa gaatagcgcc ctcttgaaca
     2401 ttatcaatcg cacttaccac ttgttgatct gactttgcat ataagtgacc gtaagttcct
     2461 aaagtgattt gaatattcgc atggcccaat cgttcttgaa tagatagcgg ttgaatattc
     2521 tgctcaatta gaaatgcaac atgagaatgt cgtagcgcgt gaagcttaat cggtttgaca
     2581 cccgcttttt tagcagcttc ttttaaccag ttcgcaaaag aataaggtgg cgtaaatgtt
     2641 ccgtccaact gagcaacata ttcaaaattt ccaatacgtt tttgcaagtc ataccactgt
     2701 ctgagtttta aggaaagctt cttccccaac ccaatcgttc gataagcaca tttagttttg
     2761 ggagtcgaaa agtaccaatc atcttttgta ttataaatca atgtcttctc aatcgttatc
     2821 gtgtttttct caaaatctac attcgaccaa gacaaagctt caagttctcc aatccgaatg
     2881 ccagtataaa agagcatttc atacacaatc ttccgatggt gggtttgaat cttatcatcc
     2941 ttcaattcat tcatcacttt ttgaaactca ctgtgttccc aaaactcaac tttcttattc
     3001 tcagaaggaa gcgaagaaac atcttcaacg ggatttttag caatcacccc ctctttaaca
     3061 gcccgatcca atacaatttt taggtgccct cgaatccgat tgatataaga ttttgataac
     3121 gtttcgccat taactttttt ccgtgaatta cgtgactctg tctggcttag ttcaaataac
     3181 caatcctcaa tatcgtgact tgtaatatct cgaacacgaa aatgatagaa aaactgcata
     3241 cgcttttcga aaatgaattg cgcattctca tatgtttgac ttttgacctg tctctcgtac
     3301 cattttacaa acctatcctt gtaaaactct tcgaaagtca tttgattggt agaacacagt
     3361 tgattaggaa ttgtcttgtt aaaatcatgt gtttccatgt acttgtcata agcaattttg
     3421 gcatcttttt gtgaagcata acctcgttta gtcttctgaa cctttcttcc attttcatct
     3481 atacctagat acgctcggaa gaaccatttt tttgtctttt tatcttggta aatattttta
     3541 atttttggca tcgttccatt cctccctgta cttgagaaaa gctactttaa tagtaccgcg
     3601 cttgtactgt ttattccgca acttgaatgt gaaaaagatg ttcaattact cgggatggca
     3661 ccacaccaac ttggcgatta ttataaaaat caataccttc aatccttgca agatatgcct
     3721 tgctctcttt aatcattcgt gcagcttgac taggtttaaa gcccatctct atcaaaattg
     3781 cacgatttac catgaaatca cattttgttt ccattctctc acctcctgat tctttactcc
     3841 ttttaaaata atcctcttta taatctattg tttctcattc gatggttgtg ttatactcgt
     3901 cttgtcgagg cggagtacgt tgcacaactt gttgtgtaag cagtactttg cttttttagt
     3961 agcttgtttt ctcatttgat atactttgta attttcgttc ataatactca acctcctcct
     4021 gataatactc cgggtctgcc ttcatatttt ggagaagttt gatctgtctt ggattcattt
     4081 ctccttgttc aataatcaaa ggcaacaagg aagaatgaaa cgtttgatcg acctgtgcaa
     4141 taaaaactaa tgatggtgaa acaccatgaa ttaaccaact catagttttc tcaaaacttt
     4201 gaggaattgt atctaaagaa atggtgattg cgccataatt gctaataaag gctgcccatt
     4261 tggcatcaac ttttgcacct agatcatttg gatcacggtc ataaaaacaa attgctccat
     4321 taagtaactc aaagaacagt ttggttaaat catgggtttt tgaaataatc tttgccaagc
     4381 tttgcgcttt ctcttttcga taccgtagtt caaagcgatt ctttactttt gcctcttcta
     4441 aaggaattcc tcgtcgcttc cgttgttcat ggtccttctg ataaaagcaa aaacgacact
     4501 gactcttctt tgagcctaaa tacaaggtct caccatttga ttcattgttt atgatatccg
     4561 taccgccatg agattcactc acttgaaaag tggtccacac atggcctagt attaccttat
     4621 gcttaagttc tggaatgctg agactcccca caaaatcatc taaagtaaaa tcaatccgtg
     4681 taaagttccc ctgataatct aataccttac gaaaaaactg ttgccaattt gtttttcgtg
     4741 tttttagcca tcttgctaag tgtttacagc cttgacctga aaactccatc acagttcctt
     4801 taaccgcatc gtcaatggaa taccgaatcg tgattacttg attccacacg tattggccaa
     4861 tatagccctt tggcgcataa tccagttcct caaaacgttc aatgggcatt tcaataatct
     4921 cttcaattag ctttaaatgt tgattcgaga aaaagtgaat ggttagataa tcaatcaaaa
     4981 cacggttaac tggaacgacc tcttcttgca aactatccaa cacaagattc aatttttctt
     5041 cacttaattg tctcgttcct ttttctactt tcgataataa ctatctcgaa atccccactt
     5101 tttctgctaa atatcgttgt gtccaccccc tttcttctcg agaaactcga atggcttcac
     5161 cgagatcatg ttgattaact tggttcatcg acaaacctcc ttctgctatt tacttgtcaa
     5221 agaacctatt gaacttattt taagtacatt tttattgtac gcctgtattt attttaagtc
     5281 aatatgtttt gacttttttt aagtacacac gtatactaaa tttaagaact tatcctgagg
     5341 aggagttttc atggagatag acaagcaagc agtcggcaat cgaattcggc agattcgcca
     5401 agaattaaag ttgagtatgg agaaatttgg caaactaatt ggtgatttac cgcgaagtac
     5461 agtcaataac tgggaacgtg ggatcaacct tccaaaaacc gaaacccttc accaaatcgc
     5521 agagataggt catgtcacca atgaatatct tttgtatggt gatcaagaga atcaatacat
     5581 tttagaaatg ctccaaaaaa aggcaggtaa gcttgatcct aagattgaag gtctcatagt
     5641 agacgaaatc aaacacgctg accttgttag tgaaaaagaa atggatcgaa tgattgaatt
     5701 ttttattaca aatctcattc caccaactga acaagaccag tttactttcc aatgtatcga
     5761 tgaaaaaaag cagctttatc ttggttcaac taattttggt aaggaagccc agctctattt
     5821 gcaacatgat aatcaaaatc atattctgca catgatgccc tttaccttct ccaactttag
     5881 tgtggatcgc atactcgtct atttagcaaa tcaaaaatcc tattcctatt ttgggaaaca
     5941 tttacccaag gaactaggtg agaaagccat ccttctatac tcaattaatc aattgaccag
     6001 cgatgtgcga attgccccgt tggtctattc agaagaaacc gcttcttatc agtacacaga
     6061 ggacaatcaa tatctactag aacagcaata tctttatcta ccattcgtga tggaagtcga
     6121 gaaagaacgc ctgttaaatg cagcgtatcc atcatcaaaa tgaggtgaca aaattgataa
     6181 gcacgtgaca aagaaaatac tgctaggaca ctccccaatg ggtagttgtc acagtttcct
     6241 gttctttgtt agccccctgt tagaaccggg ggctttattc ctgcagtccg gctacgcctt
     6301 cctgcaatag acaaaactcc agatcgggta attcgcttgt ggcgaaaccc gacctggagt
     6361 ttgtctctgt attttgaacc ctaaaaatta atcaaacaga ctgatattct cataatcagc
     6421 gcgaaataag ccattaagta cagttttcct acctattttt gataacccgc tggttagtta
     6481 atattccttt tccgagagag ataaatgatt ggttaaatct atatacatct caacctttaa
     6541 aaatgttttc gaaatacttc atcagtacat gtcatacaaa ttaccagtgc attctcaaat
     6601 tctagttctt taattgattt cagttgagga gcagttactt ttggcggaaa tttccatttt
     6661 tgtccaaacc tcttcccccg atgaaatttc tttgttgcaa ttattgcaat gaaaaatttt
     6721 tgtttcaaaa atatacataa ttacttcctc caataaaaac tatctacctc tcaaattatt
     6781 tttctctaat aagaaaaaca gaaaaggtaa taagatacaa cagtgatgat tcctaataaa
     6841 gaaaagacta caataatatt tttctaactt atcgccttca aagaaatagt ttcttatttt
     6901 tcactaaaat aaaaaattta ttgcaaaaaa aatagaagtg acaaaattat caatcatttc
     6961 aaggtaatat aactacctga gtttattatc gattaaaatg ctaactacat ttgcaagaga
     7021 agcgagagtt aaaggtaaat atagaatttc tactttttta gcaatagaaa taggaataaa
     7081 atatttaaaa tgtatagaaa ctttcttttt ttttcttgct atctttttat aatcacaact
     7141 ctctataata gaattacgat ttattttata cggctgaaaa aatctatcac caaaaaaatt
     7201 caaacattaa gccaaggatt atgaagtcaa catttcgaaa aatgaacata cattggtaag
     7261 caactataac tattaccaca gacataaagt aacacaatat attactattt aagtgtacgc
     7321 caccagtgaa tatcctcaag gtatacagcg cacaacaaaa agaaaaaagg aaacgcagaa
     7381 gcatttcctt tcagtgattt aatgaaaaca acacgatttg acttagagcc tttttatttg
     7441 aattcatttt cgctttatcc aacttcattt gatcatttga ttactcggtt aaatactttt
     7501 gacatgagta tcaatgaaac attcattaat tatggttgct tatttcttac cgcttttctg
     7561 gccaatgcta atccgccgat tattccggca ttatcaccta attcgggcgt aataatgtag
     7621 ctatcaattg gtggtatttc aacatatcca tttataagct caacaaattt atcctgaact
     7681 tttttcttca tgtgttcttg tttcattaca ccaccgccaa aaataattct atctggcgaa
     7741 aacatcagtg ttgtattgta tgcacattgg gcaaggtaaa agtcttcaat ctgccaaaac
     7801 gaatcgtcag ccaataaatt ctggcctttt acacccaa
//
LOCUS       DACGMI010000096         7760 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.100, whole genome shotgun sequence.
ACCESSION   DACGMI010000096 DACGMI010000000
VERSION     DACGMI010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.100"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(552..1898)
                     /gene="gor"
                     /locus_tag="IXT46_002730"
     CDS             complement(552..1898)
                     /gene="gor"
                     /locus_tag="IXT46_002730"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAQ4948612.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2032..3273)
                     /locus_tag="IXT46_002731"
     CDS             complement(2032..3273)
                     /locus_tag="IXT46_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAQ4948613.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(3291..4214)
                     /locus_tag="IXT46_002732"
     CDS             complement(3291..4214)
                     /locus_tag="IXT46_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAQ4948614.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4435..6927)
                     /locus_tag="IXT46_002733"
     CDS             complement(4435..6927)
                     /locus_tag="IXT46_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAQ4948615.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6934..7401)
                     /locus_tag="IXT46_002734"
     CDS             complement(6934..7401)
                     /locus_tag="IXT46_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAQ4948616.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7537..7610)
                     /locus_tag="IXT46_002735"
     tRNA            complement(7537..7610)
                     /locus_tag="IXT46_002735"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7574..7576),aa:Arg,seq:acg)
     gene            complement(7668..7741)
                     /locus_tag="IXT46_002736"
     tRNA            complement(7668..7741)
                     /locus_tag="IXT46_002736"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7705..7707),aa:Pro,seq:tgg)
BASE COUNT         2161 a         1691 c         1247 g         2661 t
ORIGIN      
        1 aaatcagtgt tttgtcctga gtattagaga aacaaatgga aaaatagttc ctcatatttt
       61 gccgtttttt gagctaatac cgaaggacag ctgattgaac actatttgtt cggaaaaagt
      121 gactaactat gacacaattt ttttcacagt cccttttttc acttgatttg attcgtacca
      181 gcgaacttga cgagaacttt cttggtttgg taactatatg gtattctttt aacatcctcg
      241 tttgcttctt ctaatttatt tatacaaagt cacacttttt taaacatctg ttcttcgata
      301 catttctatt tcttttaaac atcgatacca atattttgaa cttaagagtg cataccaaat
      361 ggattcattt actcttcgtc agttacgaag ataatcaaaa tctccaactt ccctacttat
      421 ttcgttttga gaattatcga agcaatctta cataaataac taaaaaacaa aaaaccagaa
      481 aatcagtata ctgattttct ggttttacat ggtttgttca ataaaaagct gttggaactg
      541 ttaatattaa attatcgcat cgttacgaat tcttccgctc ctgttggatg gatggctact
      601 gtattgtcaa agtcttcttt agttgcaccc atcttgatag ccacggcaaa accttgcagc
      661 atctcatcga caccaacacc aatagcatgt aagccgacga ttctttcttc ttttccgaca
      721 cagatcaatt tcatttcgca tttttggcga taatcattta atgcaaagta cattggggta
      781 aagcgtgaac gataaacttt caattcattt tcgccatatt tttccaatgc ttcttcttct
      841 gtcaaaccaa ttgttgcaat tggtggatgc gtaaagacga ctgtcggaac aagtttatag
      901 tcaagataag aatctttctt tccattaaat aaacgttctg ataaacgtct accagctgcg
      961 attgcaacag gagtcagatc taatttaccg atcacatcac caacagcaaa aatatgttca
     1021 tccgttgtat tttggtattt atctactttg ataaaccctt ttttgtccaa ttccacattt
     1081 gtattttcca gacctaattt ttcggtattc ggtacacgtc caccggcaaa aagtacacaa
     1141 tcaccagtta aggtttcacc attttcaaat agcaccgtat attcgtcatt gtttttagta
     1201 atttctttag caatatgatg tgcgtaagtt tttattccag cttcttggta catttggatc
     1261 aaattgtccg aaagcatttt atcaaacgtt ctaagtggtc gttcttttcg atatgcccac
     1321 atgacttcac tacctaaacc acgaaataca cctgaaagtt cagccgcaat gtatccagca
     1381 cctaaaacga ttgctctctt aggtaactct gttaattcaa aaaatccatt tgaatcaatt
     1441 gcgtattctc caccaggaat ggtcatttta cttgcacggc ctccagtagc gatcaagatt
     1501 ttaggagcac gataggtttc accgtttact tcgatcgttt gactatcgat aaaagtagcg
     1561 taacctttta tagcctcgac atgattgcta tctaatcctc tttgataagc accgtgtaga
     1621 aaatcaatat atttttctcg tctttctact agaccggcga aatcaacatt ttttaaatct
     1681 gcttggatac cgtaacttga ggcatctcgt tcaattgttt ccaaaatcgt acttgcttgc
     1741 cacataactt ttttaggtac acaaccgacg ttgacacatg ttccgcccaa ttcattcgct
     1801 tcaatcagca aaacttttgc gccatgcatc cctgctctgt ttgctgaagc aataccgcca
     1861 gagccgccac caattacgat gtaatcatat atttgcattt tgttcctcct tattgaagag
     1921 atcaatcaaa acctttattt aacgatcctt tttctacaga aaacaagtgt aacacttttc
     1981 ttgaattttg tatgcgaaga tgcttaaaac agggatatat cagctttttc cttatttacg
     2041 ttttcggatc atatctccag gtttcaccgg ctgtgcgact ggcatagtta aaatcatcat
     2101 tggatttggt gctcggtcaa tggattcgcc ttcttcatta tgcataactt caacggtttg
     2161 actgaaatga ctgaatcctg gaccataaaa ttcgatttca tctcctacag aaaacaagtt
     2221 tctctgacgt atcgtagcaa tctgtgttgc ctcatcataa gataatactt caccgacaaa
     2281 tttatatact gggattttac gacgttcacc gaataattgt tcgttttcag ttggtgtatt
     2341 gtagtaaaaa cctgtagcta attctcgttg tgctactttc cataactcgt cgatccattc
     2401 ttgcttgcag acatagtttt caggatcttc catataactg tctacagccg ctttatagac
     2461 atttgacacc gtagatacat aatggatcga tttcattctt ccttcgatct tgaagctgtc
     2521 tacgccgttt tcaatcaatt ctggaatatg ttcgatcatt gacatatcca ctgcactcat
     2581 cgagaattct tcttccactt cgcctgtatc agttaaactg tttcgttctt gaccaaaagg
     2641 catatcgaac aatccatact tccagcgaca agattgagaa catccgccac ggtttgcatc
     2701 ccgcatcgac atatggttgg acaatgtgca tcgaccagaa taagagatac acatggcacc
     2761 atggataaat gcttcgattt cggtatccgt atttttacga atctctgcca cttcctccat
     2821 tgaaacttca cgagctaaaa cgacacgttc caacccttct tctttccaga attccaatgt
     2881 ctcaaaatta gttgctgaag cttgagtgga taaatggatc ggcagacctg gggcttctgt
     2941 cgcacaaatt tcgatcaaag ctggatcaga aacaatcact gcagaaatac cgacatcacg
     3001 caaactgcgg aaaaattccc ctgctccatc ttcatttcct tcatgggtga ccatattagc
     3061 agcaacgtat accttcgcat catgttcttt tgcaaaagca actccttcag ccatttcttc
     3121 ataagtaaaa ttacctgcac ggcttcttaa accatatgca ttcccgccaa tatatactgc
     3181 atctgctcca taatggatcg cggtttttaa cttttccagt gttcctgctg gcgctaggat
     3241 ttctggtcgt ttcaattttc tttttactgt catttctttc atcatactcc ttatttgata
     3301 gcagaaggat caatataaaa gaatcctgta tctaattcac ggttttcagg atgcaattta
     3361 ctgatttcgc tagtcatttt ttccgctttt tcttgatccc agctaccttc taaaatttgt
     3421 ttttttgctt cggcgaatag tcgagtgatg tttacgaatt tttcgcctgg agtaaataat
     3481 ccgtccaatt tccatgtaca gtaatgatgc tgataaagtt cattcaattc attcgagaga
     3541 ttcagatcat tgctggcaaa aatatgtgtg ccatgactat cttcataaat agaataatgt
     3601 gtctcttctt ttttaggttc cgagataaaa agacctcttt cacgatcttt ttgttcgtct
     3661 tgtttcgtat agttatagta attctgtagc agtggacgtt tggattgatg gatgcatgta
     3721 gcaccataca caagggtttc tacaggaata tcgagttttt cttccatcgc cttcatctct
     3781 tcaaaaggaa cttcacgagc aagtactgct ccaactgcgc cttttttcgc ccagaaattg
     3841 atttgacgtg cgctcgttac taatgtttca gcatcataaa tatacggtat acgcaattca
     3901 ggattttttt tcatcgtata aataatacct gtatcaccaa ctgtgatcac atctacgttt
     3961 atttctttta aaaaagccaa atattcaggt acatttttca ttttttcagg atgaatgatc
     4021 ccatttacag caatattcgc ttttttacca tacttgtgtg ctaattctac caattgtcgc
     4081 tgttcttctc gtgtaaatga agcaggcaga cgcaatccaa attgctcttc accgaaatat
     4141 agtgtatctg cacctgcagc aagcaactgt tctgcttgtt caatagtttc tactgtggtt
     4201 atgagttcga tcataatttt ctcctcctac aacttcataa tagtagcata gctctaaaaa
     4261 ctttccaata cttcttctat ttaaagtcgg atttttgaaa attatttcac aaaaaatcaa
     4321 aataaagttc gatatattct gtccaaatat aaaaagagat tgtgacaaaa atcttgtcac
     4381 aacctcttaa tcaagtctta ctattataaa aattcagcta cacaggccaa gtaactatag
     4441 ggaacctact gtttcctttt taggtccgcg aacattcaat gtgatcttac cttttgaagc
     4501 acctactgtt acgtggtcac ctaaacgaat ttctccgcca agcaaagcct cgctcaatcg
     4561 atcttcaatt tctttttgaa gtgcgcgacg gattggacgt gcaccatatt caggatcaaa
     4621 tccagctttc ccgatcacat cgattgcaga tggtgtgatt ttcacttgaa tatcttgttc
     4681 tttcaatcgt ttgataatcg ctttgctcat gatttggacg attgtatgga tttcatcttt
     4741 actcaatgaa tggaagacga cagtctcatc gattcgattc aagaattcag gtcggaaagc
     4801 tttctttaac tcttctaaga tacgtttttg catggctttg tgatctttag taacatcttg
     4861 gacattgaat ccgacatttt tttcttctcg aatttgtgtc gctccgatat ttgaagtcat
     4921 aatcatgatt gtatttctaa agtccacttt tctaccttta gaatctgtta aatgaccatc
     4981 atccaatact tgcagaagta aattgaaaac gtctggatgt gctttctcca cttcatctaa
     5041 gagaatcact gaatatggtt tttgacgaat tttttctgtc aactgtccac cttcatcata
     5101 ccctacgtat cctggaggag acccgattaa tcggcttgta ctgtattttt ccataaattc
     5161 tgacatatca acacggatca gggcatcttc acttccaaac atgacttctg aaagtgcttt
     5221 ggccaattct gtttttccga caccagttgg tccaaggaac atgaatgaac caattggacg
     5281 atcaggatct ttcaatccgc ttcgtgcacg gcggatcgca cgtgaaactg ctttgacagc
     5341 ctcatcttga ccaacgacac gttcatgcag aagtccttcc agttctaaca agcgttcgct
     5401 ttcttttttc tccaactgct gtagagggac accagtccac tccgatacaa ctgtagcaac
     5461 atcttcttct gttacacgat cagaataacc ttgctcctgt tttgcttcaa ttgcagaaac
     5521 tttttgcagc tttttacgta gtgctttttc ttgtctgcgt aattgagcag cattttcaaa
     5581 gtcttgtttt tggatcgctg cttccttttc ttgtactagt tcatcgattt ctagtttgat
     5641 cacagttgat tttgttaagt gatcggtttg atccaaacgg actttcgctg ctgattcatc
     5701 gatcaaatca attgctttat cgggtagttg acgagaagtg atataacgaa cagaaagatt
     5761 gactgctgct cgtacagctt catctgtgat ctccactcca tggtgctctt catatcttgt
     5821 acgtaatcct tgaagaatca cttctgcttc ttcaggagtt ggctcatcta cttgaatgcg
     5881 agcaaaacgt cgctctaatg cagaatcttt ttcgatatat ttttgatatt catctagggt
     5941 cgttgctccg atcgtttgta attctcctcg agctaacgcc ggtttcaaga tattcgaagc
     6001 atcaattgct ccttctgctc cacctgcacc aattaaggta tgcaattcat caatgaataa
     6061 gattacttga ccatcattat agatttcgtc gatgaccttt ttcattcgat cttcaaattc
     6121 accgcgatat ttcgtaccag caaccaaaga tcccatatca agcatcatca ggcgcttttc
     6181 ttgcatgtct tctggcactt cacctaaaat gattttttga gctaaccctt cagcaatggc
     6241 tgttttgcct acaccaggtt cacccaccag tacagggtta ttctttgtcc gtcggctaag
     6301 aatctggata agccgtttca cttctctcga acgaccaaca actgggtcca gcttgttttc
     6361 ttttgctaat ttcgtcaaat cacgtgctaa tgaatctagc gtaggtgttc cttgcggtgt
     6421 ttgccgttta tcttgtacat ttacatttct acgacgattc attccttttc cagcagaatc
     6481 accagctagc cccatttttt gtttcagaac ttgacgggct tttgaaaggc tgatacctaa
     6541 gttgatcatg attcgagtag ccatgatact ttcatctttt aataagctca tcaaaatatg
     6601 ttctgttcca actttttgag aaccagtttt cttcacttcg ctgctagcta aagcaaaaac
     6661 ttgtttcatt cttggtgaat atggaagaaa gactccttta gggtaagaac ggataccacc
     6721 ataaccaatc agatgttcaa tttcttcata aatttccgtt tcattcaaat ccatttcacg
     6781 taatactttt ccagcaattc cattttgctc gaccactaag gctagtaaaa catgttctga
     6841 actaactgat tgatgtttca accgttttgc ttcttcttgt gcaatttcta atactgcttg
     6901 ggctctttca gtaaaaagtt cttccatcta atctcacttc ccatcttcat aacttaaacg
     6961 ttccagaaat gctcggagaa tccgagcacg tgtatgatct tcatattcat tgaaattcaa
     7021 tgtgtttttt gcaattgcac tcaacatcaa gtttccttct ttttttgtaa ttatttggtc
     7081 ttcataaagt ttttgaataa tagcaaaagc atttttctca ctgattgtat catcaaataa
     7141 ctgatttatc tgctcaagta attgtttttt atctgaaatc cttacttttg caattcgtat
     7201 ataaccacca ccaccacgtt tgctttctac tagataacca cgttggatgg taaaacgggt
     7261 attaatcaca tagttgattt gtgaaggaac acagttaaag aggtctgcca tttcaatcct
     7321 tcgaatctcg atcatttcac tattttccag aattttcttt atatatgatt caattaaatc
     7381 cgaggtattc tgatgtgcca tcttattcat tccctttgac taatattgac cttaattata
     7441 acgaatttga taatagaaag aaagaagaac gctttttgtt aaataaatcc tttagaatca
     7501 acaaaaaaaa atacggaata tactattccg tatcgacgcg cccaagagga gtcgaacccc
     7561 taaccttttg atccgtagtc aaacactcta tccagttgag ctatgggcgc atattcaatt
     7621 taaaaaaatt ataaatcatt tgaaaacaaa aagcaagata aaaaaaatcg ggaagacagg
     7681 attcgaacct gcgacccctt ggtcccaaac caagtgctct accaagctga gctacttccc
     7741 gtttaaaaaa taaaaaagac
//
LOCUS       DACGMI010000097         7666 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.101, whole genome shotgun sequence.
ACCESSION   DACGMI010000097 DACGMI010000000
VERSION     DACGMI010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.101"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..1175)
                     /locus_tag="IXT46_002737"
     CDS             complement(<1..1175)
                     /locus_tag="IXT46_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4948617.1"
                     /translation="MKKSAKDRVFDELIRLTGNMSSVTAEKISKNLGISRQNASHYLT
                     RLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQINEAFHSVVGHDGSLREVIQKCIAAV
                     KYPPNGLSVLINGATGVGKSFLATKIFEYAIHEQIIEEDAPFAILNCADYADNPELLS
                     ATLFGYKKGAFTGAEKDTEGLLATANNGYLFLDEVHRLSKENQEKLFVFIDTGNYRPV
                     GENVNWHSAKVRFIFATTEKSEDYLLDTFDRRIQISVMLPTFEDRPIRERLELIQLFF
                     QNEADILQKDIIVSKEALSLMLSHPFSGNIGKLKNIIKISCADVYSRTREEPLTIGKN
                     EILIQLNMLESEVESLPIASLLIKKNQKIKTDRIKPFDYDSILEKITQLINEGNFNE"
     gene            1658..1873
                     /locus_tag="IXT46_002738"
     CDS             1658..1873
                     /locus_tag="IXT46_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAQ4948618.1"
                     /translation="MKKFIIPCIFLFLSILLFSTSILVGSYLDSSGMLIEPAFFCVPL
                     GYLTLGLAFFTALYSFVKQRLLKKYSA"
     gene            complement(2114..2300)
                     /locus_tag="IXT46_002739"
                     /pseudo
     CDS             complement(2114..2300)
                     /locus_tag="IXT46_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252699.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            2734..3693
                     /locus_tag="IXT46_002740"
                     /pseudo
     CDS             2734..3693
                     /locus_tag="IXT46_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            4224..4634
                     /locus_tag="IXT46_002741"
     CDS             4224..4634
                     /locus_tag="IXT46_002741"
                     /inference="COORDINATES: protein motif:HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4948619.1"
                     /translation="MYTIILASHKNLAKGMKETVEYILGPAPFIKVMTAYTDDNYDIE
                     KDTNILLDGTDKVLVITDLLGGSVNNHWMNYVYEKKLTKKITVIAGMTLSLIMELSMN
                     IEDYKLREKISMIIAESQKSIINCSELMEVEDND"
     gene            4627..5082
                     /locus_tag="IXT46_002742"
     CDS             4627..5082
                     /locus_tag="IXT46_002742"
                     /inference="COORDINATES: protein motif:HMM:NF015769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4948620.1"
                     /translation="MIKLLRIDDRLIHGQVAMAWTKSVSADYIIVVDDASANDKMKQM
                     ILSLAKPVSTGLDIITSADFLSTFEKRKNQNLMIVTSSPKSAFEIVNAIPGEVDSINI
                     GGLRYAEGKEKVNEYVAITSEDKNYLAKLKESGFKLIMQATPTGKAKIY"
     gene            5099..5830
                     /locus_tag="IXT46_002743"
     CDS             5099..5830
                     /locus_tag="IXT46_002743"
                     /inference="COORDINATES: protein motif:HMM:NF015566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4948621.1"
                     /translation="MIECILIGIVGYLTTIDERYFGASMMNRPIIVGPVVGLILGDLH
                     QGILIGAALEAMFIGIVTIGAALPPDVGVAGTIATALAIKSGAGADVAVTLAMPFAVL
                     AQGLNMLAFTINSFTVSQGRKAIENRKLSSFQKWHFFPLIVRLPSAVLTFLVVYFGAN
                     ATESFVNIMPEKLMTGFTVASGLLPAVGFAMLIQGMIDKKSVPYFFIGYLLAAYLGVP
                     VVGVAVAAIMVALLVIQTKRNPVNI"
     gene            5847..6659
                     /locus_tag="IXT46_002744"
     CDS             5847..6659
                     /locus_tag="IXT46_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017867010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4948622.1"
                     /translation="MGDSKLTKKEINKVFWRSFALQGSESYTDMQGMGYSFSILPALN
                     KIYQGNDEKYYEAVYRNTEFFNTTPHISTFIMGMSLALEEENAKTDQFETETISSIKA
                     ALMGPVAGIGDSFYWGTFRVIAAGIGLSLAAQGNILGPILYFSIYTLLHFLGRYGCLR
                     IGYRMGANAIEKAFENNYLESFSLAASIVGLMSIGAMTSSLVRFTIPAVFKSKGGEIN
                     VQQMLDDIFPGILSLGLTFFVYFLLKKKVKVLWIILAIFVFSIVGVYIGLLG"
     gene            complement(6875..7666)
                     /locus_tag="IXT46_002745"
                     /pseudo
     CDS             complement(6875..7666)
                     /locus_tag="IXT46_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2447 a         1408 c         1294 g         2517 t
ORIGIN      
        1 ttttcattga aattaccttc atttatcagc tgagtaattt tttccaaaat cgaatcataa
       61 tcaaacggtt tgattcgatc cgtttttatc ttttgatttt tctttatcaa taaactagca
      121 atcggcaagc tttctacttc ggattccagc atatttaact gaatcaagat ctcatttttc
      181 ccaatcgtta atggctcttc ccgtgttcga ctgtacacat ccgcacaact gattttaatg
      241 atattcttca gcttaccaat attcccacta aagggatgag ataacattag agacaaagct
      301 tcttttgaaa caataatatc tttttgtaaa atatccgctt cattttgaaa aaataattga
      361 atcagctcta accgttctcg aatgggacga tcttcaaaag ttggcaacat aacactgatt
      421 tgaatacgtc gatcaaaggt gtctaataaa taatcttcac ttttttccgt cgtggcgaag
      481 ataaaacgaa ccttagcaga atgccagttt acattttcac cgactggacg ataatttcca
      541 gtatcaataa aaacaaagag cttttcttga ttttctttcg acaaacgatg gacctcatca
      601 agaaaaagat agccattgtt ggctgttgcc aataacccct ctgtatcctt ctcagccccc
      661 gtaaaggccc ctttcttgta tccaaacagt gttgccgaaa gcagttcggg attgtccgca
      721 taatcggcac aatttaaaat agcaaatggt gcatcttctt caataatttg ctcgtggata
      781 gcgtattcaa aaatttttgt ggctaaaaaa ctttttccaa cccccgtggc tccatttatt
      841 aatacactga gtccgttagg cggatatttg acagctgcaa tacatttttg aatgacctct
      901 ctcagacttc cgtcatgacc caccacagaa tgaaaggctt cgtttatttg ctccgtatta
      961 tctacaaccg catattcatc taaaggcttc cacaaaacag gctttcccgg taatttctcg
     1021 acctttttat cttccactaa tctcgtcaaa taatggctgg cattctgacg agagatacct
     1081 agattcttcg aaattttctc ggcagtgaca gaagacatat tccctgttag tcgtatcagc
     1141 tcatcaaaaa ctcgatcttt agcgctcttt ttcattttcc cctccagttc aacgtgtcta
     1201 gaagcataat aaactatcgg ctacaatatg tctattctat atttctgttc caattttact
     1261 ttgaaacaaa aataatcgag cttaaactga tattagttat aaaactatag ttagattacc
     1321 aatcttcctc tcatacaata aacttctctc acctgcatcc aacctactta tgtgaaagaa
     1381 taactgccga ttatttatct tttttacagt tactttcgaa cataaaaaaa tcaccttcaa
     1441 atactagaaa aactactatt tgatggtggt ttagaacaat ttccgttgat tcagtatcgt
     1501 ctggtcccac atcctctgtc tcattaatca caatagcata ctccaaagga taaagctggt
     1561 tgatatctca atgcctttca cacctatcaa ttttgtcaca cttatctttt cctaggttct
     1621 attctatata atctagaaaa acaaagaagg agacaccatg aaaaaattca ttattccttg
     1681 tatatttctt ttcttgagta ttttgttatt ttcaacttcc atcctagtcg gttcttacct
     1741 cgattcaagc ggaatgctga ttgaaccagc gttcttttgt gttccgttgg gctacttaac
     1801 attaggactt gctttcttta ctgccttata cagtttcgtc aaacaaagat tattgaagaa
     1861 atactcggct tgatttgcac gtaaatcctc tgttgaagaa aagttagttt tttcaacaac
     1921 gaaccttcga gtattaagaa tggatgttga tgtagacatc aaacgtctgc ataaacattc
     1981 attttattcc tccattacca acaattattc ccaatcgcca aaagaagctt ttttcggaat
     2041 taccttctcc attttttcac ctgctggtta tattgtcttt tgtaataccg atagtcctct
     2101 tcaatcattt tcaatatgcg aaaagaacca attttaacat ggcactcaaa tcacaattcc
     2161 tagggcggcc aaaaagatac ggctcgttga tttcaagggt ttcaacgagt tcattgacaa
     2221 acccagcggt gctatcttct tttggaataa gaagttgtga tatctaaagt gagttgattc
     2281 atgttataat ttgtatgcat gattttgatc ctttcaaggg ttgaatgatt tagagtgcga
     2341 gtatcctctc gtactctttt attttaccta aaaagctcca gaaatgacga atgactcgtc
     2401 atttctagag cttttttcag agaattatgt cacaatctct ttttgttata ttgatattct
     2461 atatcttttt ttattggttt tattcccttg ttcgttatag actaaaatcc ttctttcagc
     2521 attattcaaa tcaaatggca acataataga gaaatttata gtatgtataa tcatctgaat
     2581 tcaatcaaat caaccggagt catatacgga gtcaaactat cccactgaga gtttattaaa
     2641 cgcagattgt aaaattaagc tagacaacta aaaaagtcat ttgtgctaca ctcaaaatag
     2701 ttccgaccaa agaattataa ggagtgaaga caaatgacct atacccatct tacaacaaat
     2761 gaactcgtga tgatagaagc ctatttcaat atgcatcaat ctgttaccgt agtcgctaag
     2821 acctcaaatc gttccagaca gaccatctac aatgtgtaca acttcctgaa acaaggccaa
     2881 tctatccatg actattacca acaatatcaa aaaaataaaa cacggtgcgg ccgacgaccc
     2941 atttgtttgc cagcagaaca agatgcgtat atccgaaaca aggtggcgca aggatggaca
     3001 cccgatgtga ttatcggtcg tgctgagttt tcaatttcat gttctgttcg aaccctttat
     3061 cgcaagttta aaacaaacta atttgattgc tcgaaactac ccatgaaagg aaaacggaaa
     3121 cccaacgggc ataaagaacg tcgagggaaa caagccttca aacggaatat ttcagaacgt
     3181 ctcacggact atcctgaatt tcaacaggaa tttggacatt tggaaggcga cactattgtg
     3241 ggtgtccatc ataaaagtgc tgtcatcacg ctggttgagc gcttgtcaaa agtgattatt
     3301 actttaaaac ccgaaggacg gaaagcacta gatattgaaa aagtgacaac tgactggcta
     3361 caaaagcttc cccgaaactt gttcaaatcc attacctttg attgcggaaa agaattttcg
     3421 aattggaaaa acatgagtaa tgctaacgat atttctattt attttgcaga tcctggaacg
     3481 ctgtcacaac ggggattaaa tgaacattct aatggattgt tacgtaaaga cggacttcct
     3541 aatacaatgg atttcaatca ggttgaccaa aaatttgtgg cggcggttgc ctccaaaaga
     3601 aatcatatac caaggaaatc tttaaattat cgaacatcgt tagaagtatt tttgagttac
     3661 ataagtgagg agcaattgtc taacttaatt tgacatttag aaaataataa accatatccc
     3721 atctattcaa ataatatttt accgattgaa agacttgcta atcaaagcag aatagtttat
     3781 atagataaat tattttcttt aaacttatac tcatttttag atattttata agaatacttc
     3841 atgtcttcgc cagtaatata aagaacatct gtctctccat ttggacttgg gttatctatt
     3901 ttgggtgtaa catactatac atacaaccga tacataaaag atttgacatc tggacaaaac
     3961 acaatgcttt acttcatttt tataggcttt gtttacacca tcacaaaaat cacctcctaa
     4021 tttacaaatt cattaaacaa acagaaataa aaaatcacca cgatagccgc gttcaaaaaa
     4081 atttacaaaa gagaatttta gttaaagttt ttagattcgc cccactaatt accaaaggta
     4141 ttttatttat tcttaatacg aaataattta ttgacattta gattaccaat ggtatattat
     4201 ttataaataa atggaggtgg attatgtaca caattattct tgcaagccac aaaaatttag
     4261 cgaaaggaat gaaagagaca gtcgaatata tccttggccc tgcaccattc ataaaagtaa
     4321 tgactgcata cacagacgat aactatgata ttgaaaaaga tacgaatatt cttctcgatg
     4381 gaactgataa agtccttgtc atcactgatt tacttggtgg tagcgtaaat aatcattgga
     4441 tgaattatgt ttacgaaaaa aaattaacaa aaaaaattac agtaattgca ggtatgactt
     4501 tgtccttaat tatggaatta agtatgaaca ttgaagatta taaattgaga gaaaaaattt
     4561 ccatgattat tgctgaaagc caaaagagca ttataaactg ttcagaatta atggaggtag
     4621 aagataatga ttaaactatt aagaattgac gatcgcctga tccacggtca agttgcaatg
     4681 gcttggacta agtccgtatc tgctgactac attattgtag ttgatgacgc ctctgctaat
     4741 gacaaaatga aacaaatgat tttatcatta gcaaaacctg tatcaacggg actagatatt
     4801 attacttcag cagatttttt aagtaccttt gaaaaaagga aaaatcaaaa tttgatgata
     4861 gtcactagtt cccctaaaag cgcatttgaa attgtaaacg ctatcccagg ggaagtcgat
     4921 tcaattaata tcggtggttt acggtacgcc gagggaaaag agaaagttaa cgagtatgtg
     4981 gctatcacat cagaagacaa aaactactta gcaaaattaa aggagtccgg cttcaaatta
     5041 attatgcagg ctactccaac tggaaaagcg aagatttatt agaaggtggg gaataagaat
     5101 gattgaatgc attttaattg gcatagttgg gtatttaacg acaatagatg aaagatattt
     5161 tggggcatct atgatgaatc gaccgataat agttggacct gttgttggac ttatcttagg
     5221 ggatctccat caaggcatct tgataggagc agcattagaa gcaatgttta ttggcattgt
     5281 aacgattggt gctgcactac caccagatgt aggtgtagct ggtactattg caacggctct
     5341 agcaataaaa agtggagcag gtgctgatgt agctgttaca ttggcgatgc ctttcgctgt
     5401 attggcacaa ggattaaaca tgttggcttt tacgattaac tcctttaccg tttcacaagg
     5461 tagaaaagca attgaaaacc gcaaattatc atcttttcag aagtggcatt tttttccatt
     5521 aatcgttcgc ttaccttccg cagtacttac atttttagta gtatattttg gtgccaatgc
     5581 tacagaaagt tttgtaaata ttatgccaga aaaattaatg accggtttca ccgtagcttc
     5641 tggtttactc cccgctgttg gatttgccat gctaattcaa ggaatgattg acaaaaaatc
     5701 agttccttat tttttcattg gatacctttt agcggcatat ttaggagtcc ccgtagttgg
     5761 tgtagctgtt gctgcaatta tggttgcttt attagttatc caaactaaac gcaatcctgt
     5821 aaatatttaa agggagagtg ataattatgg gagattctaa attaactaaa aaagaaataa
     5881 acaaggtttt ctggcgttca tttgctttac agggatccga gtcatacact gatatgcaag
     5941 gaatgggata tagtttttct atattacctg ctttaaacaa aatatatcaa gggaatgatg
     6001 aaaaatatta tgaagctgtt taccgaaata cggaattttt taatacaacg cctcatattt
     6061 caacctttat tatgggtatg tcattagcac ttgaagaaga aaatgcaaaa acagatcaat
     6121 ttgaaactga aacaatttca tcgataaaag ctgcattgat ggggcctgta gctggtattg
     6181 gtgatagttt ttactgggga acatttcgcg ttattgctgc tggcatcggc ttatctttag
     6241 ctgcccaagg aaacatttta ggtccaatat tgtatttttc aatttatacg ctgttacatt
     6301 ttcttggcag atatggctgc ttacgtattg gatatcggat gggagcaaac gccattgaaa
     6361 aagcatttga gaacaattac cttgaaagtt tctcgttagc agcatctatc gtaggtttaa
     6421 tgtcaattgg agccatgacc tcatctctgg tacgctttac tattcccgcc gtatttaaat
     6481 caaaaggtgg agaaataaat gttcagcaaa tgctcgatga tatttttcca ggaattctct
     6541 cattggggct aacattcttt gtttactttc tattaaagaa aaaagtaaag gttctttgga
     6601 ttatacttgc tatcttcgtc tttagtattg ttggagttta tattggatta ttaggttaat
     6661 taatccagaa taaaactaga tcagacatca acttaaacca taaaataccc aaagataaat
     6721 gtaaatatga gtaaaaagag catggtataa attattagga tctataattt atgggtctga
     6781 tgaatcagaa ttgattctgt agtgacctaa aaaagataga tgttttcgga gtggagaaaa
     6841 ttcactccgt ttttctttgc ttttcttgat gattttagac agctttgaat gctattactc
     6901 taaattgcac cagactctgc cagtttagtt tccttttcat acgctcatgg ttgtagtaat
     6961 gaatatagcc atcaatggct tgcttcaatt cttcaaagat acgatagtct cttccataat
     7021 aaatttcctg ctttaataga ctaaggaagt tctcaatgat cgaattatct aagcaggtct
     7081 ccttacggga catactttgg aagatcttat gttctttcaa cttatgacta taagctttca
     7141 tttggtaggt ccatcctttt tggagtgaaa agttcgacga tagatacatt ccgttgcgca
     7201 gatagcttcc tctaaagctt ccatgatagc caacgcactt ggcttttcag aaatgcgata
     7261 aaataaaatt tcactgttgt acatatctaa aaatggatca agatacagct tcttttcacg
     7321 attggcaccg tatttatcca tttcaaaata ttttagttct gtcgtatctg ttgtaacctt
     7381 ttgatgacag ttgcttgtgt aaaagcgtcg atgaattcga ttttttgtaa tcatgccgat
     7441 tcttccacga taagtattat agcggcgata ttttctcgta aatgatcgta cttcaatact
     7501 cagctttcga atcaaacgtt gtactttttt cttgttaaca tggaacccac ggtcccacaa
     7561 ttcctttgtc atacgtaaat agccataatc tttatattga cttcttattt taagcatttc
     7621 ctcttcgatt tcttgatctg aatttcttcg atcaaatcgt ctttgc
//
LOCUS       DACGMI010000098         7597 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.102, whole genome shotgun sequence.
ACCESSION   DACGMI010000098 DACGMI010000000
VERSION     DACGMI010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.102"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(135..425)
                     /locus_tag="IXT46_002746"
     CDS             complement(135..425)
                     /locus_tag="IXT46_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948623.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(543..803)
                     /locus_tag="IXT46_002747"
     CDS             complement(543..803)
                     /locus_tag="IXT46_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948624.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(940..1353)
                     /locus_tag="IXT46_002748"
     CDS             complement(940..1353)
                     /locus_tag="IXT46_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAQ4948625.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1809..2294)
                     /locus_tag="IXT46_002749"
     CDS             complement(1809..2294)
                     /locus_tag="IXT46_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948626.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2433..2648)
                     /locus_tag="IXT46_002750"
     CDS             complement(2433..2648)
                     /locus_tag="IXT46_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAQ4948627.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2872..3672
                     /locus_tag="IXT46_002751"
     CDS             2872..3672
                     /locus_tag="IXT46_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4948628.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3691..5559
                     /locus_tag="IXT46_002752"
     CDS             3691..5559
                     /locus_tag="IXT46_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4948629.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5552..6043
                     /locus_tag="IXT46_002753"
     CDS             5552..6043
                     /locus_tag="IXT46_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAQ4948630.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6031..6585
                     /gene="srlA"
                     /locus_tag="IXT46_002754"
     CDS             6031..6585
                     /gene="srlA"
                     /locus_tag="IXT46_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAQ4948631.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6603..>7597
                     /locus_tag="IXT46_002755"
     CDS             6603..>7597
                     /locus_tag="IXT46_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAQ4948632.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2234 t
ORIGIN      
        1 gttactatga ataacataat aagaaagtaa agtggattga tttgagatct ttttatactt
       61 caaaaaagat aacacccaac tttcaaaaat atgttttgga agttgggaca aacgagttaa
      121 tacattttaa tacattattt tttattcaaa aaaaatagca caatggcaaa gatcgtaaga
      181 gagatcataa gccccaatga atgactaaaa agaaaagcag aatcacatgc catatcatcc
      241 catatttctt caagaaaata aataagcggg aaaaagggaa ggaatagtag aacatcgatc
      301 cagcaccatt tttttcttct tttgaaataa cataaaacaa taaacatgaa cgtgcaggga
      361 agtaaaaaca aagctttact cataactaac aaaataccag ctccttttat ttttttctcc
      421 cccacattca aagagtaaca atggtatgta cttaataata gaaaaatgga tcaacttgta
      481 tgaataacag ctgaaaagat ctgcaccaaa taaaaaactt ccagccaaaa ctgactggaa
      541 gtttattttt ttctgaaata ttctaacaca aatatgaaaa agatggccga agctaataag
      601 ccgatttcgt agcaaaacaa tgagatacca gagtcgtaat aataaaatcc tctaatctta
      661 tggataaaat agatcatcgg acaagcagat aagagtaagt atttgttagg ccttttgaat
      721 aagtaaaaga aagcactggt cattatgata aatggtatcc aaaacaaaag tttacttaag
      781 acaatcaaat gatcaactcc catatttttt accaagagag atcataacat ctttatcgta
      841 aaaacaaaat atttttttgc tcattttgaa aatttaaaca tactcgttct tatccaaata
      901 tataaaaatc gcccctcatt catcgagagg cgataagttc taatttaact caattttttt
      961 tgtttctttt ggctgataag ctgttttagg taataccaat ttcagcacac cgtttttaaa
     1021 ggttccagtg attttttctt catcaacatt aggaagatag aatgaacgtt tgtaagagac
     1081 cgaatgtctt tctttccgta catagttgcc atcttcttta tcttctgtat gggactcatg
     1141 attggcggag atcgtcaaag tattatctga atattcaact gtcgtgtctt ctttgtcaca
     1201 gccaggcata tcagcagtta gtttgtattc tttttcattt tcgactaaat ctacttttgg
     1261 ataacttgaa acacctaaaa aatcattgaa tgctggacta aacacgtcat tgaaatcagg
     1321 gaacatgtcg cgaatgctag gtacatttgc catttttgat catcctttca ataagtattt
     1381 tttatttatc cctatttacg taataactct attttgaaaa aaatgcaagt ataatggtta
     1441 gctttgtgaa tatttcatct aatacgatac aaaggctatc tttctaattt gaaaaaggga
     1501 tcattaaaat aataagaaga aaatatgtca aaaggtaaaa aagtaaattc ttctatccaa
     1561 atatagaaaa attgaatcta gaaaaccgcc cgacaataaa tttcattaac tcagttgacc
     1621 gaaaatgaag tagataccaa aaatttatca agagagcaag tagagaagtg agtatattca
     1681 taagagaaat agctgtaacg aattattagg ttaatgcaaa tgcttattta tactccgtat
     1741 aactttctca gaaaaaatga taccaataat gacttgctag tactgtaaat ccgtataata
     1801 tcatctaatc aaaatggtgt tccatttgca tctgtcatcg taatcgatcc ttcgggtgac
     1861 actcgataaa aaccaacgct tccagatcct ccttgggaac ggatttgttt gctggaagct
     1921 gtgaacaaat aatctcgatc aattttttga taaaagctaa taacaatatc gtcactttgt
     1981 aattcggaac ggtgggcaat aagaaataga agtgctttgt cagagttttc taatggaaga
     2041 gaaggtacag tgctttcttg catttcagat gttgaagaaa tgctaaacga ctgaatactt
     2101 gattggctat gttgcgaatc tacattacca gtagaagtat tagtaatgga agtagtagaa
     2161 gtacttttag ttgaaccaac ctcagttgtt gaaatggctg ctgaagattc tttaacagaa
     2221 ttctttgttt tatatccaca ggcagaaaaa agtattacag ttcccaacaa gcctgcgtaa
     2281 atccctttat gcatgatagc tcctcctaaa atagattatc tttattcagt atatcactta
     2341 aacaaagaaa agcagatggt ttaaaatgaa aaaaccttcc caataaaggg aaggttcatg
     2401 aagataataa cttttttaat aattatagct ttctaatatc tttcatcaac ttttctagta
     2461 atcattggga aaaatttcaa gcagtagatc gcacaaatac ctacgacgat ataaatgatc
     2521 ttcgcaaaaa tagttgttga accaccagca atcatagcta ctaaatcaag ttcgaacaag
     2581 cctaccaaca gccagttcaa ccctcccaca atcaataaag ttaatgcaat agcatctaaa
     2641 gttttcatta gaattctcct ttcttaaatg ataaaacaat tatatatcaa aaagagaaac
     2701 attgcttata taacgctcag gaattttagc aatctatgca aaaagatgaa aatttttttt
     2761 gctcttccat tagtacacat tttttagctg aagctgtaaa tttcatgtct taattttttt
     2821 tagtgagctt ttatactgga tttgtaagaa aaaagaagga gaggatcaca tatgtcggat
     2881 tggttggata ttgcaggaaa agtagtaatt gtaactggag gttcctcagg aattggaaga
     2941 agtatcgtcg aaaatttgtt gaagcagaat gcacaagtag cgaattttga tgtaactgaa
     3001 tgccgtatac agcatgaaaa cctactatct ttaaaagtcg atgtgtcttc taaaacggac
     3061 atagaagaag ggatatataa agtaatgaaa catttcaaga cgatcgatgg tctagtcaat
     3121 aatgcaggaa taaatattcc ttctcttcta atagatagaa atcatccaaa aagcaagtat
     3181 gaattatcag aacaagtttt tgataagatg atcgctgtca atcaaaaaag tgtatatttg
     3241 atgagccaag cagttggaag aatcttggtg caaaagggat caggagtgat cgtgaatctt
     3301 tcttctgaat caggattgga aggatcagaa ggacagagct gttatgctgc tacaaaagca
     3361 gcgatgaaca gttttactcg ttcttgggca aaagagttag gaaagaggaa tgttcgtgtg
     3421 gtaggtgttg caccagggat actggaagaa accggtttga gaacacaaga atatgaagaa
     3481 gctctttctt atacgagagg tataagcgtc gaacagctga gaaacggtta cagtcgaaca
     3541 agtacgatcc ctctaggaag gagtggtaag ctgcaagaag tggcggatct agtctgctat
     3601 tatctttcag aaagatcaag ttatatcact ggagtcacga ctaatatttc aggaggtaaa
     3661 acaagaggat aaaggatagg ggggacgcac gtgacgctag taaacagatg gtaccaatta
     3721 ttgaaattac tagtcactca caagaaagtt tcaatccagg aagtgcaaaa agaaatcaaa
     3781 accagtaatc aaaccataaa aaaagatatt ggggagttga atgaagaaat tgccggtatt
     3841 gcaaaaatca tccaaaaaaa caaacatttt gaacttgaaa tttatgattt tgattttttt
     3901 gatgagatca tgcaaggaaa attgaaaaca gccagtgatt tcaattcggc atccaaaaga
     3961 atcgcttatt tactaaatag gctgatcgaa acagaggatt tcttacgtat ggatgatttg
     4021 tctgaagaag tcggtgtcag cagaggaaca gtggtcaagg atctaaagac attaaaagag
     4081 atgatcaatg attttgatgt aaagattaca ggcacaccaa ataaaggact aagaataata
     4141 ggagatgagc tagaattacg actactttta ttttattttg tttctcccta cttttcagag
     4201 acgaaaacag aacagtttct agaagaaaaa caagcaatca aacattttca gaagaagacg
     4261 aatgctagta aacaagaaat caccctttta acgaaagtta tcggtatttc tttgaataga
     4321 atctctagta actatctgtt gaagaagccc atcaatcgtt acagtgggtg ttttgaatat
     4381 atccaagaat tcaatgaact gatcaatcag ttggaagaaa tctatgaact aactttgagc
     4441 caatatgaaa aagattttat cagttttcct ttgaacatca tcaacacaag tataacgatg
     4501 ataaggaaag ctaactctga tttgcgctta tatttcgacc ccatgatgat gcgtattcga
     4561 cgattagatc tcattgatct ggatgagtcc ttcttatatc aagagatgaa acagcacctc
     4621 tctttattga taaatcgggt aatttttcgt tatcgattga ctgatttatt ttatggtgag
     4681 atagaaaaaa agtatccttt ttcttaccaa atcgctagcg aatgcataca agcattagaa
     4741 gctatcttgc aacataagat ctctaaagta gagatcagct acctaacgtt gtatttggag
     4801 ttagcatttc gatatcaaaa agagcatttt tcctctaaaa aagtagccat tgttcatacg
     4861 acaggaaaag gaacagcatt aatgatccaa agacaaatca aaaggatatt ggggagggat
     4921 atacaaataa cacatgtttc agaagaacaa tatgaaaaag tagatctaaa caaatatttc
     4981 gctgttttta caacgattcc gttaaaaaat gtaaatgaag agacaccggt gatccatttg
     5041 actaatcttt ttgatgactc ttggttaagg gcacaatggc aaaaagcaaa aaaaaagcga
     5101 ttagccgggt ttcattctac tgtttttttc tatcaaatat ggaaagaaaa aaagacgtat
     5161 caagaatatt taaacaaatt agtcgctcct ttgatcagag gctattatgt ggatgaagaa
     5221 tttgaaaaaa ggatcttgaa aagagaatat cagcaaagca catttgttaa caaagaattt
     5281 gcttttcctc acacaaccaa ccagctatct caacacattg ttttatcagt agggctaata
     5341 actgatcaag gtttagcaga aacaggagga aatggagtta tttttttatt tgccatacct
     5401 gaagaaatga cggctgaagt tgagaatgaa ttatttgagc tatacgatat cctatttgaa
     5461 ctcataaaaa tgggaataga tgagtttatt gaattagcac cgacacaaga atcattttta
     5521 aaactaatca aaagtaaagg agagagactt catgaatgat atgtatctat tcatagtttt
     5581 cgcagcttca gcttatgtgc tgcaagcagt tatcagttgg aagcaactaa agcatttcaa
     5641 tcaaacatat agcgaactgc gaagaaaagg aaaagtagcg attggtaaac gacctgggaa
     5701 aatccgttca ggcacgattg ttatgctagc tatagacgat catgatcaag ttttagaagt
     5761 cagaaaaatg caaggggtta catctttggc aaaatttcat tcattacctg tctatgcggg
     5821 tgaagatatc cattacatcg atcgttacca tccctcagtt cgagcggaag atcgtttgac
     5881 acaagcagct ttagaaaatg ccagagaagt atacttacga atagaggcag gaaatgaaaa
     5941 aagtgaacaa ccttcattgc cttttattgc tatgctcaat aattttcgga tatggaaaag
     6001 tacgatcaaa gaaaaaagga gtgacaaacg atggatatca taacaaaatt tgctgaggga
     6061 tttatgaggc tgttccaaac aggtgcagaa acattcataa gctggatgac aggaatcgta
     6121 ccagttgtct tgatgctgat ggttgcaatg aatacgctga ttgctttttt aggtgaagac
     6181 cgagtaacga aagtagccaa attatcagcg aaaaatccgc ttactcgtta ccttgtgtta
     6241 ccgttcttat ctgcttttat gttgggaaat cctatgtcat ttacaatggc tcgtttcctt
     6301 ccagaatact acaaaccaag ctattatgct gctcaagctc aattttgtca tacgagcaat
     6361 ggtgtattcc cccatattaa tcctggagaa ttgtttgtat ggatggggat tgctcaaggg
     6421 atcgaaacct tagggctaaa ttcgatggag ctggctatcc gatacttgct tgtgggactg
     6481 ctgatgaact ttattggtgg ttggataact gattttacta ctggatttgt atgcagacag
     6541 caaggaatcg ttcttagcaa aaaagtagag ctttcagttg attagagaaa ggagagtttt
     6601 aaatgtatgg tgatattaag atcgtaagag gaaacggcgg gtatggaggt cctttgatta
     6661 ttaggccgac aaaagataaa cacaagttca tctatgtcac aggtggaggt gagaggccaa
     6721 tgatcgtaga taaaatagaa gaactgacag gtatggagtc tatcaatggg ttcaaaacat
     6781 caatacctga tagtgaaatc gcgcttgcaa tcgttgactg tggagggact cttagatgtg
     6841 gaatttatcc taaaaaaggg ataccaacca tcaatatcgt ttccacagga aaaagtggcc
     6901 cattagcaca atatatcact gaagatattt atgtttcagc agtagggtta gaacaaatac
     6961 agccactaat ggaaactgat gataacaaag aaacagtaaa tactgcatct ccagataaaa
     7021 agtacaaata tgatacttct aaaaagataa ccgagcaaaa agcagagcag caaaactgga
     7081 tagcaaaaat tggaatgggc gcgggaaaag tagttgctac attcaatcaa tcagcaagag
     7141 aagcagtaga tacgatgatc cggacagtga tcccttttat ggctttcgtt tcccttttga
     7201 ttggtgtgat acaaggttct gggatcggta atgtatttgc taacattatg gcacctttag
     7261 caggaaatgc agttggatta acaatcattg gctttatttg ttcactgcca tttttatctc
     7321 ctttgcttgg tccaggggca gttattagcc aagtgattgg aacattgatc ggtgtagaga
     7381 ttgggaaagg aaatattcct ccccaattag cattaccggc actatttgct atcaatactc
     7441 aaaatgcatg tgattttatt ccagtcggtc taggtttgga agaagcaaaa gctgagacag
     7501 tagaagtagg tgtaccatca gttctttatt caagatttct taacggcatc ccacgagtta
     7561 tcattgcttg ggtagcaagt tttggattat atagctg
//
LOCUS       DACGMI010000099         7351 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.103, whole genome shotgun sequence.
ACCESSION   DACGMI010000099 DACGMI010000000
VERSION     DACGMI010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7351
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.103"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(58..354)
                     /locus_tag="IXT46_002756"
     CDS             complement(58..354)
                     /locus_tag="IXT46_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAQ4948633.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            709..1065
                     /locus_tag="IXT46_002757"
     CDS             709..1065
                     /locus_tag="IXT46_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAQ4948634.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            1075..1974
                     /locus_tag="IXT46_002758"
     CDS             1075..1974
                     /locus_tag="IXT46_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAQ4948635.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            2491..3222
                     /locus_tag="IXT46_002759"
     CDS             2491..3222
                     /locus_tag="IXT46_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAQ4948636.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            3367..5394
                     /locus_tag="IXT46_002760"
     CDS             3367..5394
                     /locus_tag="IXT46_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin"
                     /protein_id="HAQ4948637.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            5502..6599
                     /locus_tag="IXT46_002761"
     CDS             5502..6599
                     /locus_tag="IXT46_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAQ4948638.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            6906..>7351
                     /locus_tag="IXT46_002762"
     CDS             6906..>7351
                     /locus_tag="IXT46_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4948639.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT         2555 a         1181 c         1462 g         2153 t
ORIGIN      
        1 atgttcaatc agctgacctt cggtattagc tcaaagcact gatttcacaa cctctattta
       61 ggcatgtgtc tcagcaagcg gttgatagtt gatgatctgc atttttcgat aaaaatcggc
      121 gggaagctta ctccaccgtt ttaataattg atagaaataa ctctcttctg ctttgatttt
      181 atactcgctt aatatcaatc caaaactatt cgtttttttt gaagctaatt ttttataaat
      241 atccaatgct ttggttttat cttcattgac aaagagtgtt tttacttcaa tataagaacc
      301 ctcgatattt tgtgtttctt cgataaaata gatgtttttt atatattcct tcatagtgat
      361 tcctccaaag aagtctttta tttgataagt ttactctacc gaagagttgt taataatccg
      421 tgaacaaaaa gtaattcttt ttccaatagt tgttaaaggt tttttatttt ttatagtatt
      481 ttttgttatt taagaaagga ataaggttaa acaaataaca ggttgctttt tgggtctttt
      541 tccgttcaag aaactgaacg aagaaaaggg aaagttgtct cttttgtgat aagagaaatc
      601 ataataaacg aatgacttac tttccaataa attgagaaca gtcagaacca gacaaattag
      661 ttgcatctga tgaataaagt gattattcta tgacatgagg tgatacagat gaaattagaa
      721 gtgacaaaag aagcacaaga agtattgaag aataaattag aagcagacga tcaactttta
      781 ttagatatcg aaaacggtga cggtccattt gcagaaagcc aagtcagttg ccaattggat
      841 acggcatttc gattgatcat tgtcaaaaaa gatacacaaa cagatctaag tctttattct
      901 gtagtggctg atacaccagt tggaccaatc aaaatcaaag acagtgcaat actttacatg
      961 gatgatccat ccacacttgc tttagaacca acttataata gtttacaatt aaaaggacca
     1021 agcggcttga gaaaaggcaa cttgcaagtt gttcgaaaag actagaggga taaaatggga
     1081 aaattggcga tcatcagcga cctacatgtg gacatcaata aattcggcga atcagagctg
     1141 atgcagcttt ggcaagtttt gcaaaagcac aagatcactc ggcttcatct agccggagat
     1201 acggctaata aagtagaccg ttgcctagct gttgtcgaat ttttcgtcaa taaaggatta
     1261 tctacgacat ttcatttcgg caatcacgag ttggcagatg tgcccaatga acagatgatg
     1321 gaccattttc cagacccaca ttttttaaat gaacggtata ttgctttaaa tgagcagacc
     1381 gttcttttag ggatgaatgg ctggtacgac tatcagtttt ccgaattgaa agattacgag
     1441 gcaatcgtac gaatgaagcg tttgtattgg tatgatcggt tcatccagcg tgggaaaaca
     1501 gatctcgagg tcaatgcaga aatgcttgca gctgcaaaaa atttgctaga ccagctggaa
     1561 gcaaaaaaac ttgaggtgat tttatccact catttcgttc ctaaacgggc atttatcatg
     1621 tatcaatctg ctccttatga gcgttggaac aaattaaatg catttttagg atcagaatca
     1681 ttcggagaat tacttgaccg ttattcaaat atcaaacaag tagtttttgg ccatacgcat
     1741 cgtcgctttg aagataaatc catcggtcac acgatttaca gctgcagacc ttttggttat
     1801 tattatgaat ggcagctgac ccgagatttt gtcttgaaag aacagttgct agacagctat
     1861 gatcctatga aattacgtgt cctcttgcgt gcccatcacc cagcttttca ggcctatcaa
     1921 acacaacatt tgcaagagga atttgaacaa gcgatgacaa tcgttccgta ttgagacagc
     1981 attagtaatg tgtaaaagaa aataccttgt aaaacataag gataagtaag agcagtagat
     2041 ccatttatcg tggatatgct gctttttttg cggaaaataa tcagcgaatg tttatttgat
     2101 cggatgattt gtaactcgca gagtactaga tgcaagcgtg tattcttttt ttgaacgata
     2161 atcacaaaaa aaaatataat atacattttt tatttaatta taattaatat tgattgaagt
     2221 ctaggcagtc aagtcacatt ttgatagata ggagggggac ttacgaatta ttttaaaggc
     2281 tatgacagct gtatttctag attgtgtttg catcaagttg caataaaaac tagaaatcaa
     2341 atcgggctga taatcattta taactaatcg atacatagga ccaaatatag gtctatgttc
     2401 ttttatttca taagtatcgt aaaacagaat tttgctatgg attaatccaa tcgactgata
     2461 tgtttagtaa ataaagaaag aggaatgtca atgatgaaaa aagaaatcgt attaacagca
     2521 gcaatgatgt tattcagcat ggtagcaagt acgacttttg tttctgcaac tgaagtatac
     2581 ccaaaggaat ataacacaga aggaacgatt acatttgaag caggagatga gggtgtaact
     2641 cctcctgttg atccagagaa tcctgatccc aataaacctg tcgatccatc agatcctcca
     2701 agccctggaa caggaggggc attatcgatt gattatggat caaaattcaa atttgggact
     2761 caaaaaattt ctactgcgga taaaacgtat tatgcagctg ctgatgtgat gaacgatggg
     2821 tctagaaaac cgacatatgt ccaagtgaca gataggagaa gtaccttatc tgggtggaaa
     2881 ttaagtgtct ctcaaccaga acagtttaaa actgccagtg gggatgaact agttggagca
     2941 cagctgaaat ttacgaaagg gcaggctgtt tctttggttg atccaacata tacgccgcaa
     3001 acggtgaatt ctgaattaac gttgacaccg ggaggaaaca atacgttagc aattaatgct
     3061 aaatcaggaa caggtgtggg gacttgggtc tatcgatttg gtgcaaatga aaatgaaaat
     3121 caagatgcgg tacagctttc ggtacccggt aaatctgtca agttagcgca acaatattcc
     3181 actaaattag tttggacatt agaagataca cctaacaact agtttactga aaagaactgt
     3241 taaaaataaa tacgtagtca tattgtcttg cgaggtaatc gagcaaaaat tgtcaaaggc
     3301 taggctaaat ttgtttggat acgaatagtt catctaggaa tttaacgatc aggaggaaaa
     3361 gatatattga aaaagaggag gatcgtgctc attttaagca gtctcttagt gactaatatc
     3421 tttccgatca tagggtactc tttggaattg aatcagttgg agcatggaaa tagaagagac
     3481 gaagaaagca aactcacttc gacattcgac agtttaatag aatccaacca gacacaagaa
     3541 agcagtgagg atttaagtat ttcgagtagt ggagagacca ctgacaacgt agaagctgag
     3601 ggttcggaca aacaaggact agaagatgca ccaatttctg cggttgagct gcctgacgat
     3661 cccaatatta tttctatcga taaaattttt caaacaccta tcggtactag cacgtccata
     3721 ttggaaaatg ggaagttact gcagttgaac ccagcagaaa ggtctcaaag aggagctatt
     3781 tggtcaaata agaagattag tttactctcg gattttacat ttaaatctta tttatactta
     3841 ggaaatcaac gagatagagc gggagatggc atgaccttta cattgactgg cgatcctaga
     3901 atggctagta atcccagtca agttattgga tcgccaggta tgggaattgg ctcatattct
     3961 actcgttctg gccaacctta cattgcgaat gcgctctcga ttgagtttga tacgtataaa
     4021 aatagtggtt cttctgatcg aatggatcga gagataactg ctgataatag agggcatgga
     4081 catgtcgctt ttgtcacgcc taaaccaaat aataataatt attctggaga gcatactggc
     4141 gtgacggtag ctcctacatt tctttctaat ggcacatggc gcttgttaat aattaaatgg
     4201 gacgcggagc aaagaagtct tacttatgat ttggaaggtg tcggtcactc ttctcggatt
     4261 atacctgatc tcattaggca gtttggttct acagaagtaa attgggggtt tacttcttca
     4321 acaggtactt tttttcaaga aaatgctgtc gctgtcacgc gacttccatc gaatgtcaca
     4381 tcaacagctg atgtaaaagt caacgatagt gattatgggg ccatcgctga agctggagga
     4441 aacgataaga taactatcag aaatacattg aaggtcgagg gggattttct tgaatataag
     4501 aaaatgcaga ctagtatcga cctcccacaa gaattaacta ttcccgagca tatcttgatc
     4561 aatggaaatc aaattgatgc caaagatatc ttgataaccg gaaatcgagt cacgctaaat
     4621 ctgacagatt attttattgc tggagatacg ttaataatcg aattggagac aactttgcag
     4681 gaagtaattc ctgaaaaagt actcactatg cattttgaat accttgaaaa cgggaatttg
     4741 attgagcaat cgaatgaaat aaacctaaag atcgcaaagc tgaaggagat agatatccat
     4801 gtttattata aagataaaga cagtcagatt gatattgctg aaatgaaaac aatcactggg
     4861 aaaataggag agaagtataa agaaactcct attgatattg aagggtatgt ttttgactcg
     4921 gattcagcga atacagaagg catcttctcc gaaaatacag aggatatcta tttttattac
     4981 agaaaaggca aactttatct ctcaactgct cctcaatatg tcaattttgg aaaacataaa
     5041 atatccagta gaccattaag tgaattcgga cagttttcag gtgggttgaa aattatagat
     5101 gaacgggctt ttggaagttg gaaattacaa ttgaaacaag agaaagttct tacaaatgga
     5161 gattttgagc ttccagaagc tctttccttt gttacctctg aaaatacaac ggttataggg
     5221 acatccgctg ttacgatttt cgaaagtgat caaaagggtg aaagcgattt gtcctctctt
     5281 ttagattcta cagctcatcg tggaatcaga atagatattc ctgtagaaaa ccaaagaatc
     5341 ggaacctttg aggggaaact atcttggata cttgcagatg tcccaggaaa ttaacaggaa
     5401 gagaagaata taacaaaatt attgagtttc aagaagggca caggtaccat aggctcttgt
     5461 gtcccacaga gacaagattt tgttatagtc ttctcttaca tatgattaaa ggagcgattt
     5521 tcttgagacc aaaacaacaa ttatttataa cactcctagt tattttaggg gcacttttta
     5581 acaatatatc agtgtcagct agtgcattta atttttcagt gacgccgata acttcagaga
     5641 atcaaatcga caagagaaaa acttacttcg atcttcaact tgatccggat caggaagtag
     5701 aagtaaaagc ggaattgaga aatgatacag aaaaagaagt gaaaatcgat atttctgtga
     5761 atagcgcaac caccaattca aatgtgatgg ttgaatacgg aaaaaacgag attgaaaaag
     5821 acatgagcct gatctttgat ctggtagatt atgtgagcta tccacagata gtgacgctaa
     5881 aacctaaaag tgtccaaacc gttgcttttc atgtcaggat gccgaatgag cgatttgatg
     5941 gtgtattggc tggtgggatc acattccaag aaatccagac ggaaaaggac caaacagaaa
     6001 ctaaggatca aagcttatcg attgagaatg aatacaccta tattattgct ttgttgatgc
     6061 aacagacact gaacgaagtt gctccgaacc ttactcttca tgaagttaaa ccagatcaaa
     6121 tcaatgcaag aaatgtcatc ttagcaaacg ttcaaaatga tcaaaaaacc tatatcaatc
     6181 aagtagttat tgaaacaaaa attacaaaaa aaggacattc tgaagtttta tatcaagagg
     6241 aaaaagaagg attgcagatt gcgccgaata caaatttttc ttttccaact gctttaaatg
     6301 gtcaaccgct aaccccaggt gaatatcacc ttacaatgac tgttttagga aatgaaaatg
     6361 aaaatggaaa attttcgaga aaaaaaggaa atactacgat caactatacc aatcaatggg
     6421 tatttgaaaa agattttaca atagacggaa aagtagccaa ggaattgaac acgacggatg
     6481 ttacgattaa aaaagacaat aattggattt atatcttagt agcttcactt ttcttattgt
     6541 ttattttatt atgcatactt ttgtttgttt tgagaaaaaa agaagagaaa gaaaagtaag
     6601 gttaagataa caaatagtaa atttttatta ttgtaggatg gttgggctct ttttataaca
     6661 atataaaata taccatttta ttaataaaaa tgcatactag taaatgatat aattctaata
     6721 acaggtttga tcgcgagaaa ggccaaataa aacgctctcc aaaatgttaa aaaaaagaca
     6781 ggacgatgta tattatacaa acaagaatcg ctgacaacag tgactcggat ccaggaaatc
     6841 agttttatcc ccagctagtt ggtgaatgca tggaaagtaa tatacgtaga aagagctgat
     6901 gactaatgaa ttatgagttt tttttaagca aagaagatca cagaagttat tcattactta
     6961 aatatttaga agcaagctca aatttatcag agtcaatatc gaatgttcaa gaagagttgt
     7021 cgctatcgac atttctcttg aaaaaaacga tcgataagct gaaacatgat ttacaaaagt
     7081 tcgatctaga gaaaaatttg cgagtaaccg tcagtgaatt ggatatatgt ctggaaatta
     7141 atggaaaatg ttctagcaaa gctctgttat ctcgttatat aacggattct ttatctatga
     7201 aaatggtatt ggctttcttt caggaaaaat atatctcagt agaaaatttt gctaaacagc
     7261 atcacgtgag ttattctgtg gcttataaag tattacaaag actaaaaaga aatctaaaaa
     7321 aatatcaaat tttttttgaa aagagaaagt t
//
LOCUS       DACGMI010000100         7326 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.104, whole genome shotgun sequence.
ACCESSION   DACGMI010000100 DACGMI010000000
VERSION     DACGMI010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.104"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..548)
                     /locus_tag="IXT46_002763"
     CDS             complement(<1..548)
                     /locus_tag="IXT46_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4948640.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAA"
     gene            complement(587..1705)
                     /locus_tag="IXT46_002764"
     CDS             complement(587..1705)
                     /locus_tag="IXT46_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAQ4948641.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(1702..3801)
                     /locus_tag="IXT46_002765"
     CDS             complement(1702..3801)
                     /locus_tag="IXT46_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAQ4948642.1"
                     /translation="MTINEVIYSPKHPLFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(3852..4673)
                     /locus_tag="IXT46_002766"
     CDS             complement(3852..4673)
                     /locus_tag="IXT46_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4948643.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLGCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(4670..5479)
                     /locus_tag="IXT46_002767"
     CDS             complement(4670..5479)
                     /locus_tag="IXT46_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4948644.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFVMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(5501..5995)
                     /locus_tag="IXT46_002768"
     CDS             complement(5501..5995)
                     /locus_tag="IXT46_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4948645.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(6007..6495)
                     /locus_tag="IXT46_002769"
     CDS             complement(6007..6495)
                     /locus_tag="IXT46_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4948646.1"
                     /translation="MFLKVGTGIAYMKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDYEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQEIKMTILDEVHVVNEEED
                     FF"
     gene            complement(6572..>7326)
                     /locus_tag="IXT46_002770"
     CDS             complement(6572..>7326)
                     /locus_tag="IXT46_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4948647.1"
                     /translation="FKQIAEDAADKYSINVQYFEGFSQSSNIIISCMSGLGISDKLKD
                     VFRHHLSDESIEVFTKEYRELRELIDQNDETYFDKTKLVITTSDLPRSFSIPNINVYD
                     ILDGDGAANLKHILSSEMKPVEFNRLIQELIKFFSLEGIADRLNFLNPTIVMSEVETV
                     ISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKAEEPNYDMKPDEDEFYYVSR
                     SIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
BASE COUNT         2211 a         1689 c         1235 g         2191 t
ORIGIN      
        1 gctgccatcc cctctaaaca atcttggtgg aagggacagt ttcctgaaaa attgtccttt
       61 ggatgtcgct tgatcaacat atgccccatt tccggatgac tgaacccttc cacgaaagtc
      121 ccattgaaca aggcaccacc tccgatacct gttcccacag tgaagtatgc aacacctgct
      181 aaccctttgc cagaaccagc aacatattca ccatagcaag ccgcattgac atctgttgtc
      241 cattcaatcg gaatattgaa atattgcttt agcgttccta caaaattgaa attttgccaa
      301 gcaagttttg gtgttgatgt gatatgaccg aaactcgttg atttgcattg aatatcaatt
      361 ggaccaaagc agccgacccc gatgcctgcc aattgttcct taaaaggttt aaaaaaatca
      421 atgacctgct tcattgtttc aactggagtt gttgtgggaa aactgactct ttccaaaatc
      481 gttaattcct cagtaccgac tgcacagaca aatttagtcc ctccagcttc aattgcccca
      541 tatatcatca taggttcctc ccttcgaata tgtgaaaaac acttcattaa cgcggcaagc
      601 gttctcgatc agtgaaatga cgtttagtat ttcctgaagc ttctgttgaa taccagtaag
      661 cgacactagc aacatcgtct tgccgctcaa ataagcgaac atcatcgttg ccgatttgtt
      721 gtaaagtgac cgataaatct tcggtaaaac agatggggtc ttgaagatgc caacgataaa
      781 gaccatgtcg tggcattgcg tcgtcaccaa aggcatgaac ggcattcaat tttcccgttt
      841 caaaacgatc tcttgtggca tctctatttg attggtaagg ataccctaaa aaggctgttg
      901 aatagttttt cgcatgtgga cgtccgaact catcgtactc atgaaaggcc cacgccccgc
      961 caaaataatc ttctgaacct gttgaggtta cggtcggata ctcactatcc ccatcaatgt
     1021 agaatttaaa ctcgccttcg ccccaccaat aacgttctag gcaggtaagc gcaaggtaag
     1081 tacccacgta atagccttga ccctttaatc gatcaattaa cttataatcc tcctgtaatt
     1141 tggtaatgcg ttcccgatgc caatttgcgt gaaaatatag gctattttct tccaattcgt
     1201 ccaccaaagc gtaatttatc gtataaaaaa atgaggacat atccttcgga tgtaaattct
     1261 cgatcgtaat tttagcggat gtttggaaag gcatttcgaa ataggaatta aagccccctg
     1321 taggattaac cactatcggc aacgagttca cctcgcaacg ctctccaaac ccattacaaa
     1381 agaaatcccc taaaggactt tcaacagcag ggctatccga cccatcccaa taaattctta
     1441 agattaaatc acgtaaaaca aaactgccaa attctgttcg atcacgaatc gtcatccaca
     1501 tatgacgaat tattcccgtt ccagtaatat ccgcaatcac agtttcttca ccagaagtca
     1561 gcggaattgc gccacgacct ttgcggcttg gtcctagctc gcttggcaac atcgcagctt
     1621 tacctttctc gcctgttgga ttttcgggag tgattgctcg actctggatt tttttaaatt
     1681 gggtaatatt ttttagtata ctcatctttt tctcctttga atgtgaatcg tttttccctt
     1741 ttctacgtga agaatttttt tcgtatcact tattttcaat ggcttttctg acaaatttga
     1801 aatactcaac tcggattgcg tacattcaat cgaaatgaag gcttgaccga acttcaaatt
     1861 cttccaagaa aacgttaaat tatcaacagg atcaatttgc aatactcctt ttttgaattt
     1921 caatccgaaa tattgactga tcattaggct gacaaaaaga cccgatgccc agccgcattt
     1981 gccgcagcca aagtctcgca cgacttctcc ttgttgagcc tctaagcgat acggccacca
     2041 ccaccacgaa ccgtctaaat ctgccaaaca aattagttct tctaatcggg ttacgaaagc
     2101 ttgagggttg tgcagctcgc tcattaaaac agtgataaag ccaggaaaag tggcgccgga
     2161 ttctaatccc caagtgatgc ctttgatttc ctcgctatag gttggattga aagaactagc
     2221 agaaaaggcc atggtgttct gatataaatg atctttatta tctaaaaatt gataaaaagg
     2281 catcaacgta gtgtctgatt cttctccatc atgcatcaat aaattaattt ttccatccac
     2341 aatcacatca cttaaaaaga ttaacccttg ctcaagaatc ggtttttgat agtgcttcac
     2401 tgaataggtt gttttctcct catcaccgat tccctccaaa aattgctcac caaaaggacc
     2461 atcgatagtc atttgtttac aaattgattc ctttagttta caggcaatgt ttttgtatcg
     2521 cttgctaaga ctcagttgtt ctagggcttc aaaaatttct gcaagtccaa tacaggcctt
     2581 ccaaagacaa agattgctgc cggtatgata ctttccaagt gcaaaggcgt ctgataacca
     2641 aacagatgga aaaagcattg gttcccctga ccgacgttga gctaatatgt cctcaataat
     2701 tcttgaagca ttcagtagaa cctgcggaca ccgctcaaag aattttgtat ccccagtatg
     2761 ttcaaaataa agactagcca gtaacgcact ggataacgaa ttactcagag aatgattgat
     2821 acctcctgta aattttgaac caggaaactt aacgccatat tgatcaaacc atagaaccgt
     2881 tttttgacat aactccggtt caaacatggt gaatggcaat gatgcgtaat acatatcctt
     2941 attccaaatt cgattagtag caggatagct gccccaattg ctgccgacga cctgtccctg
     3001 tcgattcata ccgaaactag aaaagctttg ataaagtgca cgacgataga gatggacaac
     3061 tctatcgttt ggcattgaca gctgcccaaa tagctgagca aaatagttca atgtttcctt
     3121 cagccatttt tcgatatcag attcctgaaa agtcattact tcttcaaaag catttgggtc
     3181 cacaaaagca atggcgaagc ttgccacttc ctgttgtgcg atcgtgtcct tatttccttt
     3241 ttgagaaatc aacacatttt gctgatccga atacttctct tgatacgaag gcacatcttt
     3301 cactgaaact tgaaggcttt cgtgtgtttc attcacaatg taaacctgtt gaacaagcat
     3361 acttaaacgc ttattagcca gtatgggagc aaaggatact acaatgacct taaacgtcga
     3421 ataatgatga atatatctag gcaaacagtc ttgaatcaca tcgacttcaa tacgatgatc
     3481 cgattctgac aaatggtaga caatcccgtt tacttcaacc tttaaggata acgaattggt
     3541 ttgagagagc tgtttattga cccaaacacc tggtttttcc tcagttagta aattttctcg
     3601 ataaaaggtc aacgtttgaa tcgtcccgca aacatcaagg tttgctaatg tcttttgatt
     3661 acttacatcg aaggtcaatc cctttacatc aggaatattc cgatagtagc tgtattcgtt
     3721 tgaagtagtc acatttccgt cgtttaactc agcattaaat aatgggtgtt tgggtgaata
     3781 aattacttca ttaatagtca tcttttccct ccttgctaaa aaaactgcag cctagtagct
     3841 gcagcttcct actatgcgat tccaagtaat gacaataaaa ttcccaagac gaccattcca
     3901 aaaataattt tgatgacgcc gactttttta tctagtaatt tgaaacagcc caatgttacc
     3961 aataacggta caattccttt aaaaatacta tcgaggattt cttggacatt cattagttct
     4021 tcgcccttca ttgaaaagct caaaacggta ttgaatttga ccatactgat cgtcattgcg
     4081 cctaccatga tcagacccaa gatactagca gcttttgtca gaatttcaat taacccgttc
     4141 gcatacagct tttcaatata tttagagcct aatgaatagc ctaaaacgcc gccatagtat
     4201 cgcatcaaat aattaggtat attgaacata actaaaaaga taattggtgc caaaatattt
     4261 ccggcattgg ctaagttgat cgctagtccc gcggtaacga cacgccaaac tccccagaac
     4321 aatgaatcgc caattccagc caatggtccc atcaaactcg ttttgatcgc gttgatactt
     4381 tccacgtcaa aaccagcttt ttcagaattt tccttctcca tcgatgccgc aatccccatg
     4441 acaaaggacg cgcaaggaat ggtcgtcgaa aaatactgtg tatgacgttc cagcgccgca
     4501 gctcgatctt cttcactttt gtagaaatga ttaatgaagg gcatcataga ataggcgaaa
     4561 ccaccgccgc ccatcgtcac cggattcacc gaagcataca tagtcatcga gcgccaaaac
     4621 atcttccgaa ccaatttttt ctcatcttta gaaattccat cagctaattt cattgaaaga
     4681 aatcctcctc ttcttggtca agcgttgcat ttacagcagc atcgctttga actgcatgaa
     4741 cagatatatt ttttagttgt agatctcttt gggctataac aattgcaata atcgttccaa
     4801 ctgcggcaat tgcaatcaat ggtaactcga gatacgccat aacaacggcc ccaaagaaaa
     4861 accacacagc aatattttta ctccaaagca tccgtaacag catagccatc ccaactgccg
     4921 gcagcagatt tccagcgact gttaatccgt tcatgatgac ctctggaata ttatccaaga
     4981 cgcttttgac aacatctgct ccaaataaaa cggcaaagaa tggaataaga gcataaagcg
     5041 catagtggac aaaccacata acgaagtgca gattgatgat tcctttttga tcaccagatt
     5101 ttgcaaattt gaaaaattta gcagccatcg gtccacatac aaaagaaaaa atcatattca
     5161 ttaactgtaa tcctaatact gctagtggaa agacaatggg aataatcgca tccacgtttc
     5221 ctcccatttt gattgcgaac gctgtagcca acccagcagc caaagaaggc tccgccgtac
     5281 tagagattcc gatattgacg acacccataa aaatggcttc tagtgacgcc ccgacaatca
     5341 accccgtctg caaatccccc atcaacgctc ctgctaacgg agcaacaaca atcggacgac
     5401 tcagcatgga catcccgaac atttcatgtc cagcaactcc aataaaaacg gccaaagcga
     5461 ctacaaatgc atcatacata atttttctcc ttcctttttt ctaaaaatca ctcaaaatag
     5521 agatagctga acgtttttcc atcgccggtg taggctgaaa aacggtatct ggataaagtt
     5581 caactaattc ttttaagtct tgaatttctg acgtcgttaa catcacttcc tttgataagg
     5641 ttttcttatc ttccgatggc ggtgtcattt tcccagcatt ccccacgttc attaattcga
     5701 tttccgttgg gaaagctttc gcaactttta ccgcatcttt gacattaggg actaaaacca
     5761 tcaagcgcat gtccttcgcc cgcggatctt ttaacaaatg aatcgcgtca tcaactgttt
     5821 taataatgac tttgacattc gatggtgcag ccatcttcaa tgtcatcttt tgaatatcgt
     5881 tggtagccgc ctcatcgctg gctactacta acccggttaa atttagactc tttgtccaag
     5941 tcatcgctac ttgtccatga attaatcgtt catcaattcg cactgcttta atcatttttc
     6001 ttcctcctaa aaaaaatctt cctcttcatt tactacatgt acctcatcaa gaatggtcat
     6061 ctttatttcc tgttggcatt tatttaccag ttcctgaata tcctcctttg ttaattcctt
     6121 ggttgccaat actatttcga gcagaattgg cagattaaag ccagacaaaa tagttacagc
     6181 aatctctttc tccaaaaagg ttttggtaat cttctgattg acacttccgc caaataaatc
     6241 ggtaaaaaca aaaatctgat cctgctcgtt cacctggttt acaaatacat tcaactcctg
     6301 ttcataatca cactcatcca cataagcatt aatcaccgta atctcttgaa ccttccccgt
     6361 cagtaattga atactgctaa gaaagcctga agctaagtga ccgtgagtcg ctattagaat
     6421 tttcttcata tggttaattc ctttctttct gttcactttc atataagcaa ttcctgtgcc
     6481 aacttttaaa aacattggtt taatcacgtt aattcacata aaaaaaagtg tctaacctga
     6541 aaaaatcaga ttagacactt ttttagacac tttatttttg aatatacggt cctaataatt
     6601 catagagcag cgaaagctca taagcattga ctttaaaatt atatttcatc tccattgatt
     6661 gaaaaatact tctcgaaaca taataaaatt catcttcatc tggtttcata tcataatttg
     6721 gttcttctgc tttttctgtc cgcgccaaga ataaacgttc catcatcaat gccgtatgca
     6781 tataaagatt tagttttacg cggccattta aagtgaaatg atagtaattt tcatatttag
     6841 aaatgactgt ttccacctca ctcatcacga ttgttgggtt cagaaagttc aaacggtctg
     6901 cgattccttc caatgaaaag aattttatca gctcctgaat caaacggtta aattctaccg
     6961 gcttcatctc agaactcaaa atatgcttca aattggctgc tccatcacca tctaaaatat
     7021 catatacatt gatattagga attgaaaagg aacgtggaag atccgaagtc gtgatgacca
     7081 attttgtctt gtcaaaataa gtttcatcat tttggtcgat taattcacgt agttctctgt
     7141 attccttcgt gaaaacttcg atggactcat ccgataaatg atgacgaaaa acatccttca
     7201 gtttatccga gatacccaat cccgacatgc aggaaatgat gatgttgcta ctttgagaaa
     7261 agccttcaaa gtattgaaca ttgattgaat acttgtctgc tgcatcctcc gcaatctgtt
     7321 taaatg
//
LOCUS       DACGMI010000101         7156 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.105, whole genome shotgun sequence.
ACCESSION   DACGMI010000101 DACGMI010000000
VERSION     DACGMI010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.105"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(558..1598)
                     /locus_tag="IXT46_002771"
     CDS             complement(558..1598)
                     /locus_tag="IXT46_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAQ4948648.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1947..2273)
                     /locus_tag="IXT46_002772"
     CDS             complement(1947..2273)
                     /locus_tag="IXT46_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948649.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2260..3048)
                     /locus_tag="IXT46_002773"
     CDS             complement(2260..3048)
                     /locus_tag="IXT46_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4948650.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3416..3706)
                     /locus_tag="IXT46_002774"
     CDS             complement(3416..3706)
                     /locus_tag="IXT46_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAQ4948651.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3842..4021)
                     /locus_tag="IXT46_002775"
     CDS             complement(3842..4021)
                     /locus_tag="IXT46_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948652.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4018..4368)
                     /locus_tag="IXT46_002776"
     CDS             complement(4018..4368)
                     /locus_tag="IXT46_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948653.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4361..5686)
                     /locus_tag="IXT46_002777"
     CDS             complement(4361..5686)
                     /locus_tag="IXT46_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAQ4948654.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6136..6750
                     /locus_tag="IXT46_002778"
     CDS             6136..6750
                     /locus_tag="IXT46_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4948655.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6915..>7156)
                     /locus_tag="IXT46_002779"
     CDS             complement(6915..>7156)
                     /locus_tag="IXT46_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948656.1"
                     /translation="SFMYRDFYEESIELTPTEPNKSQITLSKELERKVESQELAIGIS
                     ITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
BASE COUNT         2188 a         1290 c         1062 g         2616 t
ORIGIN      
        1 gttgcgggta ataccgtaac actgaagggc acgcattaag gcgtcatctt aatgctttcc
       61 tgtaggacac tgacggagat taccagtctc ccgagcctta caggggcctt tctttttttt
      121 gtattttcaa ttatcacaat ttatcgtcca aaagtgcaga acgaaaatca attcatcaca
      181 agcatatcag acaattaaat ttaaaacaac taaaaatata caaaaaagtg taattgaata
      241 ttagcagcac tgcctgaaaa gaagtaatat caggcttttc agcttgggga aataagtgaa
      301 ttacctctct tcatgaatta ttataactca aaaaagcaca tatgcaaaca ctagttccct
      361 atttttttga atgaaaaata actaaaatat ctaacgatta tgactttaaa acctacgttt
      421 gtgattgttt tcataaactt ttaatctaaa aactccggaa taatagctat ttatttgtaa
      481 catttgtaat aaaattaaaa tcataaaaaa gttctaattt aaaattgatc atttttatag
      541 tgatcgcttt ttatcaacta ctctagccaa ttttccgtac taactgttgg taattcgtta
      601 aatgtttctc tttgttcgtt tgcaagcttt gccgcaatag ctttttcgac aaaccaattt
      661 tttacataaa cgaaaattag attctgcaaa ttgtttactt tttcagtttt ttgtttttga
      721 taagctttca gcaaagtcat atataatcct ttgtcagcat caattccata agattccagt
      781 tcttcataaa caacaactgt ttgctctaat tcttcagctt ttttctttgc attatgaata
      841 gtttggacgg ttttttgagc gtcttcgtaa gtactagaaa atgtttttat caagtttaat
      901 acattttctg gtacaaatgt atttatactg tcctctttca tgatgtcgac gaagttatct
      961 agtaaaactt gattttgtaa ctgatcagtt tcagtgtcta ttatgtgtct attagtgtct
     1021 atagaattag aatagaatag attgtctgcg attttcgcaa ttacggttga gtccttgata
     1081 tgactggatt ttgccgtatt tgcgattttc gcaattacgg tggtatcatt gatttctcgc
     1141 ggttttgccg tatttgcgat tttcgcaatt acggtggtat cagtattgtc ttcctcttcc
     1201 atgattttaa agacgtcttg attcgttact tctggcttgc ctaagtacaa taaattaggc
     1261 atggattcaa tcttaccgtc acgtttattt actcttcctc tcttctgttt cagaagacct
     1321 gctttttcta attccttttt gattttagat actttacctt cgcggcattg taacaatttc
     1381 attaattctt caactgtgaa tatgaaaaat atattatcat cagaatctac ccagttattt
     1441 ttgactgaat aatcaaatcg atctttaagt agcatataag caatttttgc atcatttgat
     1501 agatccatgt atttttcgtt agtaaaaaat accttaggca tttgataata tttttcacga
     1561 taaatttctt ttgatttgta ataattaaaa tcattcatag ccaatcctct ttctgtagga
     1621 tagcgttttg ttcaaaacta tgttacaatg aattaaacaa atatatctat ccactatata
     1681 tttttctact gctgataagt cgccaaactt tgttaaagca gtagtctttt tttatctttt
     1741 tttagtttac cttaaaaaat aaattaaagc aaaccgctct atttcaaggt ttaagctcat
     1801 agtaactata tcacgatatt acaataatat tatatcacga tatcgtaata ttacaatatg
     1861 aagataagcg acttatcagc tttgatacta ctgattttta taaaaaaaat atcacgatat
     1921 tatgatatcg tgatattgaa tgtaaattaa attttatttt gtttctttgc tagtttatat
     1981 ccttcaatca agtattcttc aggtatggac tttaatagcg catcttctat aacgtctggt
     2041 ttacttttgt ctgattcagc aatagtcgtc caatatttga gtgctgacat tagaattgga
     2101 tttatacgaa tgctatctgc tgttcttaca ctacttcctt gatcttttat gactttactt
     2161 atatttttct tggttaattc gatttcttct acttcttttg atttaaaatt ctttttattt
     2221 ttatttccta gtaatctact tactgcagct tgactgcgat tatcttctgc catcaaaatc
     2281 accaacttct tttaaatatt cttctgtaaa tgctttatag tcatcttcag ctgttgaggg
     2341 tttattaaaa ttgattagat ctgatccagc agcttgcgct tcgtcaacgg ttattgtcct
     2401 acgaatataa gttttgaaaa tttttgcacc aatgactcta gaaatttcgg ttgctgcaga
     2461 cgtcatttct ttagaaatgt tataacgctt attatactta gtaaatagaa ctcctcgtac
     2521 ttcaagcttg tcgttcgtat attcttttac cgtttcaata gtttcactta actttattag
     2581 tccttttaat gagaaatacg cagcttcaac tggaatgata atttcatcag aaacagtaaa
     2641 tgcgttgact gtaagcattc ctaaacttgg tggacaatca attataatat aatcatagtt
     2701 gtccttgatt ggttgaagta ctcttttaag cctgtgttca cttcctactt gagtaaattc
     2761 cctctctgca gaagaaaggg ctatgtcggc tggcaaaaca tcaattcctt tatagtccag
     2821 aatagcatct gtaatgtcag cctccccttt taatacttca taaattgtag gttggtttgt
     2881 tccatctata tcgaaaccta cattatctgt agcatttccc tgaggatcaa tgtccactaa
     2941 aagtacattt ttaccgtaaa caaatttcaa acatgctgct aaattaacgc tagtcgtagt
     3001 tttagaaact ccaccttttt gattggctac tgacaatatt cttgccatta aaatatcccc
     3061 cattcatctt atattataat ataattatat cataatattg tgatattgca atatcgtata
     3121 tgcattatat tgtaatattg tgtgattatt ttgttttaaa gatatatatc ggttcggata
     3181 taaagattat tcatatgtta ttcgaaatta aaataatcac tttttattac tttaaaattt
     3241 tttattaatg ataagaaata tgttttgcga gcagcaacta gaataattta aacattacta
     3301 aactgtctat attgttacta ataattccct tcttatagtg cattttctta gaaaaaaaca
     3361 atattacgat atcatgatat taagatatcg taatattata caattgtgat tgatattata
     3421 tatgtttttt tattttttta tcatgtttaa tcttgaagga atcatattct ttttctaaag
     3481 acaggagctt ttcataaaca tcagacatgt ttaaactaga ggccaggctt aaatcataaa
     3541 cgaatgaagc aggtaatgat tttattctac gttgtcgggt tatccagctt gcaaccgttc
     3601 cttgtgggta ggcatataac tcacaaaatt gttctacagt gattcctaaa ttcttgataa
     3661 tgtaaacatt gatcgggtgc gagtaaacaa atgtattgat agacatggtg cgtaagccta
     3721 ctttctttta ttattgcgtt tgcaataata gtttaacaca cgcattattc tagtatctac
     3781 tcctatttgt aaaaacaaaa aaggattcat agagataact ctatagaatc cgtaaaatac
     3841 cttatatata taacgggaag atataaaacc taaaattatg ataacctgct gcagcttcta
     3901 catagaaaga gaagcgctca acaccaacct catttatcaa acgttggcca taaccccaaa
     3961 tctcttctga tagctgatca aaggttatat actttagctc atattgctgg ataatgttca
     4021 ttctaatcga ctccatttat tatcctggta aaattcgata tgacgtattt cgtcgtagtg
     4081 aattttgtct tttccaacgt agatccccag ctcatcacta cctaagatct tgccaatgat
     4141 atcttctgga tagtatcctt cagcgtttcg ttcttctttt tgaatagata ctgatctatt
     4201 ttttatgact gcagcgttca atacttccgc aatctcttca gtcgtcattt gttcttttgc
     4261 taaattttga ctggttcgtt gttcattgtc ggcatcaatt tcttcagtat gatcagataa
     4321 ataaaaccct gcccacttta aacgtccacg atcattgtaa tcaatcattt ttaattcccc
     4381 catttccgcc cgcatgacca ccaacaagtg tgcttctagt aatgcttcta gcgccttcta
     4441 acattgaaga agcatgtaca atcgacgtaa aaccatattt ttgccgaatc ttgtcaataa
     4501 ttttatctaa attttcttcg tcaatttgct tttgtggatc actaaataaa tccagctgaa
     4561 gcgaatcggt gtacacaagc ttgctatagg ttattccaac atgccttact tcttgtcctt
     4621 cataatactt atcaaacaag aaaagacaat aattctgcaa ttcctttgta ttatctgtga
     4681 tagggatctt catctggtgt gaaaaccctg gtctcgtttc taagatcgac gtgccaatgt
     4741 gtaaatggac acaacctgtt ttacagttat gctgcctaat gcgtatcgct acttgttccg
     4801 ccatttcttt taccaccagc tcgatttcat ttcttctagt ataatctcgt ggtaacactt
     4861 gtgaatttcc atatgatttt tcctttgtcg gttctggtgg gattgctata tctgttcgat
     4921 cgatcccatt agcatggaag tacagctgta agccaatcac acctagtcta ttcttaatcg
     4981 tataaggatt ccagttagca agatctctaa tgctcataat ccccatctga ttgagtcttt
     5041 ttttcattcg agagccaatt ccccaaaagt ccgtcatttc aggaatattc catacttttt
     5101 caggaacgtt ttcgtacgtc cattccgcaa caaatccttc attatgcttt gcttcgttgt
     5161 ctaaggctag tttagccaaa aggggattat ctccgacacc tactgtagca atcaatccta
     5221 gctcttcttt aatattctcc tggatcattt gagccagctt ctttctccgt tgacttcgtg
     5281 ttccttcagt cgtaaaaaga ttcagtgatc gggtcacttt taagattgat tcatcgatcg
     5341 agtaaatcag tagatcttca tcagccacat atcttctgaa aatattattt acctgcatat
     5401 ttcgcttgat atataggttc atacgtggtg gaacaacgtg tagtgtttta ggaaatggtt
     5461 gtggtaagtc acgtggtcta ctcacatttg taataccata ccgctttttt gcttcaggag
     5521 aagaagctaa tatcaatcct gaaccagtat tatcagctcg actcataaca acaagttctg
     5581 ttgttaatgg atctaaattt ctttctatac attcgacact tgcgtaaaag cttttcatat
     5641 cgattaaaaa gtaatcattt actggctctt ttgaataatc catcataaat aacactccat
     5701 tctttcacat tatacaaaca tatgttcgat attgtaaaga agaaatagct aaatacataa
     5761 aaaaagaagc ataggtatgc tatcaccctg cttcttcttt tgatttgtat gatcaattta
     5821 ttctatcact ttactaatta atttgaaaat ctaataaaaa ctctcactct aaaagagtga
     5881 gagactgcaa attagagtac ggactttttt ggagttccgt tctttaatat taacaaatga
     5941 ataaaatcct tacaacattt gagaataagt tatcagtaga cacttacaaa aaattctcat
     6001 actatttcct ccatcattag tttttgtcta tataaggttt accctaaata gacactggta
     6061 taacattgaa aaatatggct tcctcgtgta tgattagggt gtattttaaa tagttgcaga
     6121 aagtaggtaa aagttttgag agttgcatac atacgtgtct catcgatcga tcaaaatgaa
     6181 caacgccaga ttgaagaaat gaaaaaattc ggtgcagaga gaattttcat cgagaaacaa
     6241 tctggcgcaa cgattactca tcgacctgtt ttccaagaag cattagatta cgtccgagat
     6301 caagatattt ttattgtgga agctattgat cgacttggaa gaaattatga cgagatcatc
     6361 gcttcagtca attacttgaa gaagaaaaat gtgaagctga tcattactag tttaccgatc
     6421 atggctgaag caattggcaa tcctctcctg gataaattca ttaaggatct gatcatccaa
     6481 attttggcca tgatcgctga acaagaacgg actgaatcga aacgtcgcca ggcacaagga
     6541 attaagatcg caaaagcaaa cggcgtctac aaagggcggc ccaaattata cagtgcagac
     6601 gcaaaagatc cccaacgtcg ccttgtttac aaaagcatcg ttgaagatct taaaaatggt
     6661 gttgcgattg ctaagattgc taaagactac aatgttacga gacaaaccgt gtatagaata
     6721 aaaaaagaca gcatggtcaa tgacaaatag ttgatcatgc tgcttttatt atcttctcat
     6781 ctttaatttc ctacatataa ttactatcta taaaattaag tcttactcag aacagataaa
     6841 gcataaaatt ccaacaaacc attttttact taactaaata aagagtctgt taatataatc
     6901 ttcacttatt tacgttaatc ccctactgta tttgttggtt ccttatctat attttctaca
     6961 aaatccttat tatcttgtga tttagcttcg tataattctt tgtatgtcga cacattggtt
     7021 atactaattc ctatagctag ttcttgagac tctacttttc tctctagctc ctttgacaaa
     7081 gtgatttgag atttatttgg ttccgttgga gtcaattcta tagattcttc ataaaaatct
     7141 ctatacataa agctat
//
LOCUS       DACGMI010000102         6624 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.107, whole genome shotgun sequence.
ACCESSION   DACGMI010000102 DACGMI010000000
VERSION     DACGMI010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.107"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            70..153
                     /locus_tag="IXT46_002780"
     CDS             70..153
                     /locus_tag="IXT46_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAQ4948657.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            278..1015
                     /gene="erm(B)"
                     /locus_tag="IXT46_002781"
     CDS             278..1015
                     /gene="erm(B)"
                     /locus_tag="IXT46_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAQ4948658.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1185..1445
                     /locus_tag="IXT46_002782"
                     /pseudo
     CDS             1185..1445
                     /locus_tag="IXT46_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
     gene            1608..2273
                     /locus_tag="IXT46_002783"
                     /pseudo
     CDS             1608..2273
                     /locus_tag="IXT46_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284571.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2309..2554
                     /locus_tag="IXT46_002784"
     CDS             2309..2554
                     /locus_tag="IXT46_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAQ4948659.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2657..3526
                     /locus_tag="IXT46_002785"
     CDS             2657..3526
                     /locus_tag="IXT46_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAQ4948660.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3507..4241
                     /locus_tag="IXT46_002786"
     CDS             3507..4241
                     /locus_tag="IXT46_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4948661.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4274..5182
                     /locus_tag="IXT46_002787"
     CDS             4274..5182
                     /locus_tag="IXT46_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAQ4948662.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5179..5721
                     /gene="sat4"
                     /locus_tag="IXT46_002788"
     CDS             5179..5721
                     /gene="sat4"
                     /locus_tag="IXT46_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAQ4948663.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5814..6608
                     /locus_tag="IXT46_002789"
                     /note="aph(3')-IIIa"
     CDS             5814..6608
                     /locus_tag="IXT46_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAQ4948664.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2322 a          996 c         1388 g         1918 t
ORIGIN      
        1 tttgtgtata ataggaattg aagttaaatt agatgctaaa aatttgtaat taagaaggag
       61 ggattcgtca tgttggtatt ccaaatgcgt aatgtagata aaacatctac tgttttgaaa
      121 cagactaaaa acagtgatta cgcagataaa taaatacgtt agattaattc ctaccagtga
      181 ctaatcttat gactttttaa acagataact aaaattacaa acaaatcgtt taacttctat
      241 atttatttac agatgtaata acttcaggag tgattacatg aacaaaaata taaaatattc
      301 tcaaaacttt ttaacgagtg aaaaagtact caaccaaata ataaaacaat tgaatttaaa
      361 agaaaccgat accgtttacg aaattggaac aggtaaaggg catttaacga cgaaactggc
      421 taaaataagt aaacaggtaa cgtctattga attagacagt catctattca acttatcgtc
      481 agaaaaatta aaactgaaca ttcgtgtcac tttaattcac caagatattc tacagtttca
      541 attccctaac aaacagaggt ataaaattgt tgggagtatt ccttaccatt taagcacaca
      601 aattattaaa aaagtggttt ttgaaagcca tgcgtctgac atctatctga ttgttgaaga
      661 aggattctac aagcgtacct tggatattca ccgaacacta gggttgctct tgcacactca
      721 agtctcgatt cagcaattgc ttaagctgcc agcggaatgc tttcatccta aaccaaaagt
      781 aaacagtgtc ttaataaaac ttacccgcca taccacagat gttccagata aatattggaa
      841 gctatatacg tactttgttt caaaatgggt caatcgagaa tatcgtcaac tgtttactaa
      901 aaatcagttt catcaagcaa tgaaacacgc caaagtaaac aatttaagta ccgttactta
      961 tgagcaagta ttgtctattt ttaatagtta tctattattt aacgggagga aataattcta
     1021 tgagtcgctt ttttaaattt ggaaagttac acgttactaa agggaatgga gataaattat
     1081 tagatatact actgacagct tccaagaagc taaagaggtc cctagcgcct acggggaatt
     1141 tgtatcgata aggggtacaa attcccacta agcgctcggg accccttgta ggaaaatgtc
     1201 ctaagtgtgg caacaatatt gtattaaaaa aatcgtttta tggttgttca aattatcctg
     1261 aatgtaagtt tactttagct gaacatttta gaaagaaaaa actaaccaaa acgaatgtaa
     1321 aagaattact ggagggaaaa gaaaccctgg taaaaggaat caaaaacaaa gagaaaaagc
     1381 cctacaatgc cgttgtaaaa attggggaaa agggatatat tgattttatc tctttttcaa
     1441 aataaacatg gggctgaccc aaaagtagct cctatatgaa aaatagaggt ctttccattt
     1501 agatagtagt ggaaagacct ctatttatct tttgaaagtg aatacaaaaa taaagcacac
     1561 tctgctataa tataggtgat taatccattt gagagaggtg ctttatcatg tatcaaaatt
     1621 ataccataaa ccaactttgt ttgcctatag atcttgaaat taaattagaa gaaaatgatt
     1681 ttgctcatgc cattgtgcag tttgttgact ctattcccga tgaagtcttt cttccttatt
     1741 atcaatctat gggtagaccc caatatcatc ctcgtatgct actttccatt attctttgtg
     1801 cctatattca aggggtttat tcgggccgcc aaatacaaaa tatgctgata gatagtattc
     1861 ggatgcgcta cttatctcaa gagcaattcc ctaactttcg tactattaat cgttttcgcg
     1921 ttcatccgat tatgaacgat attctagatc attcatttgt tcaatttcgt gagctactgg
     1981 ttcaaagtgg cttaatcagt ggcagtgctc tatacattga tggtacaaaa attgaagcgg
     2041 atgcgaataa atactctttc gtttggaaaa aaagtatttt aaagtataag gatagccttg
     2101 atcaaaaagc ccttgaaaac taccaacaaa tggtggaaac aaaaatctta cctgagttaa
     2161 tagatgattt aaaggatgaa ctttctatag aagagattga aaggattcgt caatctttgg
     2221 aagaaaagga aaatcaatta attgaagcga ttgaccaaac cgaaacagta gaagggggct
     2281 gacccattat taataaggag tggacaacat gattgatgta aatgagctat tggaagaagc
     2341 tattagagaa actgaaaatc taaatgatgg cgaagttttt cttgttaaag atttattcaa
     2401 gggatatgtg gggaatagga tacccagaaa ggatcgactt ctgcttggaa cgttattttt
     2461 aaaccatgtt agcaaaatga atggtaattt aaaggctatt gaaaagactt catctaatca
     2521 gcagaggtat aaaaagacaa ttgataagtt ttaactatct tttgtgaaat taaaaaaatt
     2581 ataaatatgt tgagtagaag caaaagattt ggcttggaat ttttacagca gtgaatcgat
     2641 aaaaggagca tgcttgatgg tagataatat tattaaatca gtagcagaga aattatcctc
     2701 tctgtcttat atagaaggta ttgttttagg tggttcacgt gcaaggggca cccatacaga
     2761 ggattcggat atagatatcg gcatctatta caattcagaa tcatttgaca taaatactat
     2821 taatcaattc gctacaaagc tggatgatga gcatagaaat aaccttgttg tacctcccgg
     2881 agcatggggt gattggatta atggcggcgg atggttagtc ataaacgggt atcatgtgga
     2941 tttaatttta cgtgatatta aacgtgtgga acaaataatg aaagatacag agcacggaat
     3001 tgttactgcc aattatcaga ctgggcatcc ccatggttat attagtgcaa tgtatcgagg
     3061 agaattagcg attagcaaaa tactatatgc taagaatgaa agcttatgcg aattaaaaaa
     3121 acaggcagaa acttatccca atgctttgca gaaaagttta gttaactttt ttatgtttga
     3181 agcagggttc tctttaatgt ttgtaaaagc aaattcggga acagacgata aatattatat
     3241 tgcgggtcat gtttttcgta tagtttcatg tttaaatcaa gtgttatttg catgtaataa
     3301 tgcttattgt atcaacgaaa agaaagctat aaaactgctt gaaacttttg aacataaacc
     3361 tgaaaaatat accgagaagg taaatcatat ttttgaagta ctcggtatct cactttttga
     3421 atgctacgac atgaccgaga agctttataa tgaagtgaat gaaattgtat cggagataaa
     3481 taacttttta aacgaggaga gttcagatga aagaaaacaa atatgatgat aatatatttt
     3541 ttcaaaaata cagtcaaatg agtcgctcgc agaaaggact ggctggtgcg ggagaatggg
     3601 agactttgaa aaagatgcta cctgatttta agggtaagcg tgtgcttgat ttaggatgcg
     3661 gctatggatg gcactgtata tatgcgatgg aaaacggtgc ttcctctgta gtaggtgttg
     3721 atatttctca taaaatgctc gaagtagcaa aaggaaaaac ccattttcca cagattgaat
     3781 atgaatgctg tgccatagaa gatgtggatt tcccagagga gagctttgat gtaatactaa
     3841 gttcgcttgc gtttcattat gtagcagact atgagaattt aataaaaaag atatatagga
     3901 tgctgaaggc tggtggcaat ttagttttta cagttgaaca tcctgttttt actgctcatg
     3961 gaacacaaga ctggtattat aacgaaaaag gagaaatact gcatttcccg gtggacaatt
     4021 attattatga gggcaaacgg acagctatgt ttttggaaga aaaggttaca aaatatcata
     4081 gaacactgac cacatatcta aatacactgc tttcaaatag ttttataata aatcagattg
     4141 tggagccaca gccgccagag aacatgatgg atattccggg gatggcggat gaaatgcgac
     4201 gcccaatgat gctgattgta tcggcaaaaa agaagatgta ataatataga aaaaataaac
     4261 gaggagtatg taaatgagat cagaaaaaga aatgatggat ttagtacttt ctttagcaga
     4321 acaggatgaa cgtattcgaa ttgtgaccct tgaggggtca cgcgcaaata ttaatatacc
     4381 taaagatgaa tttcaggatt atgatattac atattttgta agtgatatag aaccgtttat
     4441 atctaatgat gactggctta atcaatttgg gaatataata atgatgcaaa agccggagga
     4501 tatggaatta ttcccacctg aagaaaaggg attttcctat cttatgctat ttgatgatta
     4561 caataaaatt gatcttacct tattgccctt ggaagagtta gataattacc taaagggcga
     4621 taaattaata aaggttctaa ttgataaaga ttgtagaatt aaaagggaca tagttccgac
     4681 tgatatagat tatcatgtaa gaaagccaag cgcaagggag tatgatgatt gctgcaatga
     4741 attttggaat gtaacacctt atgttattaa aggattgtgc cgtaaggaaa ttttatttgc
     4801 tattgatcat tttaatcaga ttgttcgcca tgagctgctg agaatgatat catggaaggt
     4861 cggcatcgaa acaggcttta aattaagtgt aggcaagaac tataagttta ttgaaaggta
     4921 tatatccgag gatttgtggg agaaactttt gtccacctac cggatggatt cctatgaaaa
     4981 catatgggaa gcattatttc tatgccatca attgttcagg gcggtatccg gtgaggtggc
     5041 ggaaaggctt cattatgcct atccggagta tgataggaat ataacaaaat ataccaggga
     5101 catgtataaa aaatacactg gtaaaaccgg ctgcctggat agcacatatg ccgctgatat
     5161 agaagagagg cgggaacagt gattacagaa atgaaagcag ggcacctgaa agatatcgat
     5221 aaacccagcg aaccatttga ggtgataggt aagattatac cgaggtatga aaacgagaat
     5281 tggaccttta cagaattact ctatgaagcg ccatatttaa aaagctacca agacgaagag
     5341 gatgaagagg atgaggaggc agattgcctt gaatatattg acaatactga taagataata
     5401 tatctttact accaagacga taaatgcgtc ggaaaagtta aactgcgaaa aaattggaac
     5461 cggtacgctt atatagaaga tatcgccgta tgtaaggatt tcagggggca aggcataggc
     5521 agcgcgctta tcaatatatc tatagaatgg gcaaagcata aaaacttgca tggactaatg
     5581 cttgaaaccc aggacaataa ccttatagct tgtaaattct atcataattg tggtttcaaa
     5641 atcggctccg tcgatactat gttatacgcc aactttgaaa acaactttga aaaagctgtt
     5701 ttctggtatt taaggtttta gaatgcaagg aacagtgaat tggagttcgt cttgttataa
     5761 ttagcttctt ggggtatctt taaatactgt agaaaagagg aaggaaataa taaatggcta
     5821 aaatgagaat atcaccggaa ttgaaaaaac tgatcgaaaa ataccgctgc gtaaaagata
     5881 cggaaggaat gtctcctgct aaggtatata agctggtggg agaaaatgaa aacctatatt
     5941 taaaaatgac ggacagccgg tataaaggga ccacctatga tgtggaacgg gaaaaggaca
     6001 tgatgctatg gctggaagga aagctgcctg ttccaaaggt cctgcacttt gaacggcatg
     6061 atggctggag caatctgctc atgagtgagg ccgatggcgt cctttgctcg gaagagtatg
     6121 aagatgaaca aagccctgaa aagattatcg agctgtatgc ggagtgcatc aggctctttc
     6181 actccatcga catatcggat tgtccctata cgaatagctt agacagccgc ttagccgaat
     6241 tggattactt actgaataac gatctggccg atgtggattg cgaaaactgg gaagaagaca
     6301 ctccatttaa agatccgcgc gagctgtatg attttttaaa gacggaaaag cccgaagagg
     6361 aacttgtctt ttcccacggc gacctgggag acagcaacat ctttgtgaaa gatggcaaag
     6421 taagtggctt tattgatctt gggagaagcg gcagggcgga caagtggtat gacattgcct
     6481 tctgcgtccg gtcgatcagg gaggatatcg gggaagaaca gtatgtcgag ctattttttg
     6541 acttactggg gatcaagcct gattgggaga aaataaaata ttatatttta ctggatgaat
     6601 tgttttagta cctagattta gatg
//
LOCUS       DACGMI010000103         6174 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.108, whole genome shotgun sequence.
ACCESSION   DACGMI010000103 DACGMI010000000
VERSION     DACGMI010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.108"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(624..1157)
                     /locus_tag="IXT46_002790"
     CDS             complement(624..1157)
                     /locus_tag="IXT46_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAQ4948665.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(1178..2122)
                     /locus_tag="IXT46_002791"
     CDS             complement(1178..2122)
                     /locus_tag="IXT46_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAQ4948666.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            2759..2845
                     /locus_tag="IXT46_002792"
     CDS             2759..2845
                     /locus_tag="IXT46_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAQ4948667.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(2966..3655)
                     /locus_tag="IXT46_002793"
     CDS             complement(2966..3655)
                     /locus_tag="IXT46_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948668.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(3662..3940)
                     /locus_tag="IXT46_002794"
     CDS             complement(3662..3940)
                     /locus_tag="IXT46_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948669.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(3900..4814)
                     /locus_tag="IXT46_002795"
     CDS             complement(3900..4814)
                     /locus_tag="IXT46_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAQ4948670.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(4796..5176)
                     /locus_tag="IXT46_002796"
     CDS             complement(4796..5176)
                     /locus_tag="IXT46_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAQ4948671.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(5626..5913)
                     /locus_tag="IXT46_002797"
     CDS             complement(5626..5913)
                     /locus_tag="IXT46_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAQ4948672.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(5933..6157)
                     /locus_tag="IXT46_002798"
     CDS             complement(5933..6157)
                     /locus_tag="IXT46_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HAQ4948673.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
BASE COUNT         1633 a         1153 c         1042 g         2346 t
ORIGIN      
        1 cgttttttta aaattgcttg ttatattaaa taatcttagt aattttatta tataacattt
       61 tattatataa caatgattaa cgtcataaaa agtagttttg aattcataat cgtttaaata
      121 aaattataag atcagttatt taaacagcta gtagacataa tgtgtatact accaagtaac
      181 gcctgtacca agggatccag gcgctgattt tgtgaatttt tattggtcta ggttaaaagc
      241 tctttttaag gcttggtttt ctgcggttgt ttctttctaa ttctttgtga atattgatcg
      301 gtcatttttt aaatacttgt tatttttgtt tgtgtttgtt atgcttttta catatctcat
      361 attcatttat tattcttttc taaggttaat aataggataa tctctttcag aaagactgct
      421 cgtacgagca gtcttttctt atttatcaag tttttctaca aatacttcct cattttgact
      481 gttgtagtaa ttaggattga gttttagttc ccctttttta tttcctttgt tggccactga
      541 taataacatt gggctaaagc ttaatattcc tagtaggata gaaccgaata gcaagtgttt
      601 ttttgtcata agtatttcct tcttcatttc catagctgcc accatttttt ccaattcttt
      661 gtttgttcgt ccattgtttc tgttgcttca gaaagagtcg ttgaactatt ctctgaagac
      721 tcttccgtat aagtcaactg cagttgctcc tgaagttttt cgatttgttg gttggcttgc
      781 agggtgagtt gttgttgctg gtcgagtagt ttttgtatat gagaattatt ttgctctttg
      841 agggcaagtt gttctcgtaa aaattcattt tcttcacgca actgatctag caacttgttt
      901 gcaaccacgt ttttgtttgg tatataagca tttttatcgt tgttttgttc atgtttatgc
      961 aacttatcta gcaacctttg attgtctaag ttgcgagcaa gttgcaatac tccagaacgc
     1021 aatacaacct tataaccacg ctcattttta gctatcatgg aagaatctaa tttttggata
     1081 tgtttcgata ttgcttgcct actcatctta aaaagatctg acaattcctt tattgtaaag
     1141 gtttcttgtg gttgcatact ggttgcctcc taggttgcta ctggaataaa ttatctaaat
     1201 cagataataa actttttttc tctttttccg aaagtgcgga ctctgtttgt ttttcaagag
     1261 cttttttctc tttttctagt tgtttgattt gttggaggag ttcaagttct cgtttcttct
     1321 gtttgatttt ttcgttaatt gttgtagcgg gttcttcgta ttctttttgt ttatcagcta
     1381 aagccaatgc tttattttgg tcttctttgg ttggtgcatg tttgttaaag tcgtctgctt
     1441 ttttgatctc aggtttgaac gtaaattgat agccaataac aggttttccc cgtccttttc
     1501 cgtatttctt tttgattgtt agtcctttga agattgcagt tagttcttga cgtataggtt
     1561 ttataactcg tttatctata tcaggttgct tataactttt aggaatatct aataattcaa
     1621 gaaagtcttc tttggagaaa tatgcgaaac ctttggttct gtattgcttt aacagacgaa
     1681 acatagtctt tgcatagcca ctttgtagct cgttgaattg ttgtaaagaa tagcgtaccc
     1741 actcgtctaa attatttaac aaaggcagtg ctttttcgta aattcgtata tctacgtaag
     1801 gattttctac gtccccgttg attttaaatt ctgtaaacat tacaaacata tcgtaagaaa
     1861 gcccagactc acttctacga ccaaagcgta aagataagat tttttcataa gttgctttta
     1921 aatcttctac aaatcgtaca tttgcagttg ctttgtagtt acttaaatct tttagttggt
     1981 caaacgtaaa acgaactgtc ttatcccctt tttcacgcat tctagacacg atggaaaaaa
     2041 acaaattcat ttcaaccggt gtaaattttc ttaaaggaat tgtatttaat tcatggtggt
     2101 attttacaat ctcattagcc atataatcac ctcaatccaa ttatgaatga cattttttaa
     2161 atgtcaagac attcatattt gacgttcaaa cagacaaaat gtccttcata aacagacaaa
     2221 atgtccttca taaacagaca aaatgtcctt cataaacaga caaaatgtcc ttcataacat
     2281 tctgtatcca ttggtagagt aaggacacag cttacggtaa agaggtttaa aaagaggttt
     2341 aaaaagagat ataaaaagag gggggctaat tttcccgcct aaaaaccact tcttttttct
     2401 ttaaacaggt tcgcgcattt ttcaaaactg ccaatccaaa accttgcttc ctacggtcgc
     2461 caaaaaggtg tgatcgctac gctctcacat tgtactgcgc agtcgcctaa aggctccttt
     2521 gctaaaaaca tgttggtaaa gaggcctttg agcggttctg aatgcttatc taagccgttt
     2581 taagacagtc ttggataaaa atccttatct agctttaaag cgccttacag gcggtcaggg
     2641 caagccctaa caaccctaaa ataagcgata cttaaaaaca ccacacaagt ttaatttttt
     2701 aagatataat aacttgtcgc ctatccgaca gtcttgcgac tggaaggagg tgtatctaat
     2761 gtttgaattg ttcatttgcc cccttcttat agaagtttgt gtctctttat tcagttattg
     2821 gttgaataac cgaaacaaga agtaaaatca ataaaggcga catcaacctg aaaaaaagcc
     2881 ccagagaatc cgacctctct ggggctttcg tgtatctaat gtttgatcat ttgcatgttt
     2941 agtttaacat gattgccgat caaattcaat tttgctgttg ctgatctaac cattccttga
     3001 cactttttag ataatttaat gccgtttctt ttttcgttgg attttgtatg ttcgttgctt
     3061 gctgaagcag tgctttataa cgttcgtagg taactgattg ttgccgttct tttcgttcct
     3121 gttcactagt tgaaaaaggg attgtatcac tgaataaatt ataacaagct tcttctgtct
     3181 gcgtatcttt aaaatattgc acgtcttttt tggttcgctc atagttgtct tgaacctctt
     3241 tttgctgttt ttctggcaag ttttgataaa gacgagtgag tttttccatg tttttatccg
     3301 tcaaacgttt ttcttgattc acaaaaatat cgttcatttc ctcataacaa gtggtaaact
     3361 cttccatttt ttgtgttaac acttgctcct ttttcttttt atcacatgct gcttcatact
     3421 tttgagtgat atcccctaat aaaatacttc ttgaaatacg tttatttccc tctaaaacgc
     3481 cgaataaacc acttaaaacg attgataatg taaatataac ccctggcaac aaaaacctct
     3541 taaatcgaat tttagagcct tttaatgaat atcttgtttg ataagcctta tagctaagcc
     3601 aaataattcc taaaatactg gcaaaaatga gtagataggg taaatagaat gccatttcta
     3661 tttattctcc ccataccagc caaaaggcta acagtgtcat gattaagcaa cataaggggg
     3721 caagaatatc cattgatcgc tgcataatta cttttttctg ttctttattt cgctggttta
     3781 atagcgcatg gtggaatttt ttgacttgtg aatcaattgt agtttgtatt ctttctttgg
     3841 tataaggtgc aagaaaagca cgttgtttct ttatttcatt ttctatgtct tgtaacgttt
     3901 tagaacgata attcttgttg gtagtctgct cctctttcaa cgtgttggtc atggtttctt
     3961 cgagtcggtc taatttccgg ttgttcagtc gtaagagttc gttgttctct tcgtacttct
     4021 tttgcagttt cgcgaatgct agctcgagct cttcgtagct cgttggttcg ttgttgattg
     4081 taggctcgtt ctcgtctgtc cagctcatgt aaaatcgtct ccttttcgta atcctttcct
     4141 agtttgttgg atcgtacttt tttctttttg tggatcaatt cgtaagtaaa atttttccca
     4201 cgattcaagc aatgaatgcc gaatgtttta agagaatcac aaaattggtt atacgttcga
     4261 gtttttttgt ttttcattgt ttgatcaatc gcaaaccgaa tttcgtcttt ccaaacaggt
     4321 tcattttttt cttttaattt gatttcagac atggttcgtt tttcgggttt cttccctcgt
     4381 tcagtgattg ttaagtcatg ttcaagacaa atctcgtcat ttaggtcata acatttgttt
     4441 aaaaatgctt gaccatgggc ttgaaatttg ttcccagttt ccagattgac ggagttaatg
     4501 acaatgtggt tatgaatatg gtctttgtct gtatgtgtgt aaatcgcgat ttggtggtca
     4561 ggggctattt ttttcgcata ctctgcccct agttgattgg ctttttcagc ggtaatttct
     4621 cctggtcgaa aagactggat caataagtgt gcttgtacac gatcgtcttt tccatacagc
     4681 atgcgaattt gtttcatttc gcttttggca taatcaatgt cacagtttat ccctgttttg
     4741 acggttgctc gtggttcggc gtaattgatc gctcggctac aagaagtggt tcggcttact
     4801 ttaactgttg ccatatcttt tgtagctcct tttgcatgat ttttaggttt tcggataagc
     4861 gttgggcgtc gccaggatca acgtcgtgtt ggtgtgtgtt gcaccacttg gcaatttgat
     4921 tgatattccc gccagctttg gctaaatcgc gcgcgattgc ctgagcaatg tctggcgcca
     4981 ctttcggtgt caccagacgc gcgttttgtg ccttggcttt cacgaaagcc ggcacactca
     5041 tttgcaaagc ttcagctgac tgcttcagct ttgcaaattc ggattcgctc actcgaaaac
     5101 tgatttgttt tggctcggat cgataggtat attttttaga atgattgcta gccaaatatt
     5161 gattttgttc gctcataagt cccacccttt cagtacgtcc tacggacgta tcgttcgcaa
     5221 taccattgta cctaaaaagg tacaataagt aaagctcact aaagctcact aaagggcttg
     5281 gcaagctcta tatttgctag ccaaatacct acgtatttgg tgcaaataac cgcttgtcaa
     5341 aggggcgcaa gctccccctt gaatccccct cccccccact ctccacaata caaaaaagac
     5401 tagcaaatgc tagccacttt ttgtaaagtt tcgcttgttt caccttcggt gaaattgttg
     5461 caaatcaata attaggtaga gctacatttt tttcgttgtt caaagattct tatgccattt
     5521 actattaata aatctataaa tatgataatt tttcggctct ataatttatg ggactgatga
     5581 atcagaattg attcttcagt cccattttca ttttattcca aagaattaac tccaaatacc
     5641 aatagaagcc catcctctat atacttgaga ttccttacta acaatttctt gtaattctat
     5701 taaagattta ggtaatccaa atttatgttt taaaatatat cttccaagaa aactacttaa
     5761 tttcatacta acttcaccaa cactttttcc ctcactgatt tctttagaat aaagaaagag
     5821 cttttctttt aagtcaggat agtcatctat agttgcttca ttgtatactt tactaattgc
     5881 atttaaaagt ttttcttctt tagtaaaatc cattataata acctccctac cactaccttc
     5941 taggtgccca tggaccatga ttaacccaac cattaacaat aatttttcca atttctcctt
     6001 tagcttgatt ccaatctacc caacattttt ctttgttaca ataaagacca tttccatagt
     6061 aagtagctgc atcaactttt attcctgtac cgatgccagc tagacaagtt cctaatattc
     6121 ctagaataac acaatgtttt aatactttct ttttcatgat tgtttttcct tttc
//
LOCUS       DACGMI010000104         6001 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.109, whole genome shotgun sequence.
ACCESSION   DACGMI010000104 DACGMI010000000
VERSION     DACGMI010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.109"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(51..1517)
                     /locus_tag="IXT46_002799"
     CDS             complement(51..1517)
                     /locus_tag="IXT46_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAQ4948674.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1904..2500
                     /locus_tag="IXT46_002800"
     CDS             1904..2500
                     /locus_tag="IXT46_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAQ4948675.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESSTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2558..3040)
                     /locus_tag="IXT46_002801"
     CDS             complement(2558..3040)
                     /locus_tag="IXT46_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948676.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3146..3343)
                     /locus_tag="IXT46_002802"
     CDS             complement(3146..3343)
                     /locus_tag="IXT46_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948677.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3638..4396
                     /locus_tag="IXT46_002803"
     CDS             3638..4396
                     /locus_tag="IXT46_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAQ4948678.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4456..4884
                     /locus_tag="IXT46_002804"
     CDS             4456..4884
                     /locus_tag="IXT46_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948679.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4930..5002
                     /locus_tag="IXT46_002805"
     tRNA            4930..5002
                     /locus_tag="IXT46_002805"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4963..4965,aa:Gln,seq:ctg)
     gene            complement(5152..5523)
                     /locus_tag="IXT46_002806"
     CDS             complement(5152..5523)
                     /locus_tag="IXT46_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4948680.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5738..5923
                     /locus_tag="IXT46_002807"
     CDS             5738..5923
                     /locus_tag="IXT46_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948681.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
BASE COUNT         2025 a         1160 c          993 g         1823 t
ORIGIN      
        1 aaaaacagga actgctgcaa ataagcaatt cctgttttta tgttcattga ttaatgaata
       61 gagcccatta gttttttgat tggttctttc acagtaaata gcaagatacc accgacgatt
      121 gctactgcac cgataatacc gaagtaagca gattctgttc ccggtgtgta gaagcgtgca
      181 atttgtgcat tgattgcttg tgaagaagca tcagctaaga accaaatagc gattgtttgt
      241 gattcaaatg ctcgtggtgc taattttgtt gtcacagaca aaccaactgg tgaaagacac
      301 aattcagcaa taaccacgat gaagaaactt cccaacaacc acaatggact tacttttcca
      361 cttgtaccat aaagcatacc cggcaacatc aatagcaagt acgataatcc tgcaaataaa
      421 agtccaagag agaatttcac tactgtagat ggttgacgtt caccaagttt cgtccacatc
      481 gttacgaata ctggtgtcag aataaagatg aaaattggat tcaatgattg ataccagctt
      541 gcttggatcg ttacaccaaa tagcgtagat tgtgtacgtt cactagcaaa taaagctaag
      601 atagatgaac cttgttcttg taatgaccag aaaatgattg ctgcaaggaa taatgggata
      661 taagcccata ctcttggttt ttcttcagca gttacatctt ttgaagtcag cattttgata
      721 aagtaataca acggtaagat aatccccaat acactgattg tattgacaaa aaagtcaatt
      781 gtcagatgac cagttagttg tgccccgccg aatactgcag cgataacaac aagtgcgatg
      841 atcaagttac ggatgaatcc tttacgttct tcagttgtca aaggattcgg cggtgttgta
      901 cccactccgt ctaatgtctt gcgtccttgg atgatgtatt gtaataatcc aaagaacatc
      961 ccaatagcag ctaaagagaa ccctaaatga tagttatatt cttgaccgat tgtaccaacg
     1021 attagtggtg ctaataatgc ccctaagttg acacccatgt aaaaaatcga aaatcctgca
     1081 tctcttcgca agtcagtctt tgaataaaga tgtccgacca tgccagaaac atttggtttc
     1141 aaaaaggcgg ttccgataat aatcaatgcc atcgaaacaa acaatgtact tacaccaaat
     1201 ggtaaagcca agacgatgtg gccaagcata atgaaaactc caccgaagaa tacagtgcgt
     1261 tttgctccta acactcggtc agatacccat ccgccgacga tactagacat gtagatcaaa
     1321 gatccgtaga tcgacatgat agctaatgct gttgctcgtg gtaatccaag tcccccgttg
     1381 gcaactgtat cgtacatata atagataagt aatgcacgca taccgtaata actaaatcgt
     1441 tcccacatct cagtgaagaa caaagttgac aatcccttcg gctgcccgaa gaagcccttg
     1501 tcttgctgtt tttccataat ctatacccca attctttaaa ttttcagaaa atattataca
     1561 tctttaccga aaaatttaac taaaaaactt atttaagaaa tataaactaa ttttctataa
     1621 aagcaagtaa tttttaatgg caatatcata aaaaaaagaa gatagagatt taataattat
     1681 atatcagctg tttttttcaa ataagcaaaa attcctaaaa cacaacaatg aaagcgataa
     1741 ctaagaaaat ccttacataa cgatttttct tattaaaatt gttttttgaa cttcgcttat
     1801 tttttgtgag catatctgtt tacttacttt ttgtaaggtg ttatacttca tttcgtaatc
     1861 aattaaaaaa atgcaaaacg caaatcaaag gagaaatttt attatgacaa cttttactga
     1921 cactttgaaa aaccgccgtt caatctatca tctaggacgt aatgtttcac tttctaatga
     1981 agaattaaca actttgatca aagaagcaat taaagaaagc tcaactgctt tcaatgctca
     2041 atcaacacgc gcagttatcc ttttcggaga tgcacatgaa aaactttggg aaatcactga
     2101 agaagcactt cgcccattga ctccagcaga agctttccca aatacacaaa acaaattagc
     2161 tggtttcaaa aatggttatg gtacagtatt attcttcaaa gatactgacg tggtaaaagg
     2221 tctacaagaa caatttgaat tatatgcaga caacttccca gattggtcag aacaatcaaa
     2281 cggaatcgca acagctaata cttgggtagc attagttgat aaaggattgg gcgcaaactt
     2341 gcaacattac aacccagtta ttgacgaagc agttgcaaaa gaatggaata tcccttcaaa
     2401 ctggaaacta cgttcgcaat tagtattcgg ttcaccagaa acaccggctg gggaaaaaga
     2461 atacatgaac gatgccgatc gcttccgcgt atttggataa ttttatttga aataaaaaac
     2521 agaggttgtg acaaacatct tgtcgcaacc tctgttttta ttctggatca atcataatat
     2581 caatctctgc ctcatcgttt aagcgttggg acaaaaatgg aactaattct tctaatgatg
     2641 cagaaaattt cagcatcggt cctcgccatc cgtttcggaa aaaattcatt tttacgattt
     2701 tagaaccttt tggctgatat aatacaattt tattgatctc agaaaaagga acaccttttt
     2761 tgtcaaagct attcaaaaca agtccttctt ctgtgattcc tctactgtcc aacaaaaaac
     2821 taataaaaat cattgctgac aagatccctt ttgccaattc atctgctgta ggatgactga
     2881 tgagtgtata ccaaatgact agtgacacta agaagggtat caccaagtag acccatcgat
     2941 ttcgcacagt ccgataaata atttcttttc gaaccagcca aagaaataaa aacatcacaa
     3001 caacgaataa aaacaataga accgtaaaga atgttaccat gacaactcgc ctcgcttttt
     3061 cttctccaga aaataggaaa agaatactga tttaccttct caaagaaatt ggacttgcag
     3121 cacgccgcac gtccaattgt tttctttatt caaatgtatc atattttgca acaaccatgc
     3181 ttgctttttc atctaataat tcttggtcct ctgcagcaca ttgggcaact ttgaccacgg
     3241 cgcagtttgt catttttgat acaacttcac caatgaccgt ttttgtaaaa ccaattggtt
     3301 tgcatgcata ttgttctcct aaattaatca tttcttccgt catcaaaatc ctcctaaact
     3361 gctggaactt ttctccacat taccactgct atttctttgg agatttaact cattgatttt
     3421 tatttacagt taaaaatcaa ccttacaggc attatagcgt actgttttcg ttttcacaat
     3481 taaaacagct gttgtattta gaagaatttt tttcaaaaaa ttaaaacata ttccttaaaa
     3541 actaattatt tcctacatat taaaatataa tacttccatt tccaataaaa atacatttat
     3601 aataggaaag ataaacagct gaaaagggag atttcaaatg aagaaaaaaa cgttcaaaaa
     3661 actattgttt ctagggggca cagctgctct tttattaagc ggtacaagtt attacctaca
     3721 tatccattct ccagaacata caatgaacac tgcacaaaaa agttcaacac aaaaaacgaa
     3781 aaagacaaaa gagaaagcag aagttttact agatgttcca ttagagagcc agtttgattc
     3841 tccttcttta gaaaatggct gtgaagtcac ttcgctttct atgcttttat ctttttatgg
     3901 ttatgaaaca actaaaaacc agttagctga gcaattggat tacgtccctg ttttcaatgc
     3961 agatgggact catggcgatc ctaatgaagg atttgttggt gatatcagtg gcggagactg
     4021 ggctatggtc gtctatgttc ccccagttgc ctcccttgct cagcaaatcg tccaaacgga
     4081 ttatcacact tttccaaaaa ccgatgctca actcgatgat atcaaaaaag cactatctaa
     4141 aggaaatcct gtctggactt ctgtgactat caattttgaa gtcccagatg aaactgattt
     4201 tatgacttgg accacaaata atggagaagt aagagtcact cctcttgttc atgcttgtgt
     4261 agtcactgga tatgacaaag aaaatattta tgtcaacgat ccctatggtg taaaaaatcg
     4321 agcagtaccg atcaacgatt tttcggcgat tttcactgca atgggtggac agatgctaac
     4381 tttggagaaa agctagtaat tcaaacaaaa atcccttata ctcaagatac caaacctttg
     4441 aagggagcgt agataatgga aaaattcaca cataaaaaaa tggatccaaa tgaaattccg
     4501 attatttttg tccgtgactg caagggaaat gttcaaggta aagtctctat taatgagtgg
     4561 aacgagcgtc gcagacctgc taccctcaat gaactggaaa tcaaattgta tcgtcaatct
     4621 cttgtttatt acgcagatca agagtacgag aaagccaccg atttattgaa atttctaatt
     4681 gctcgaacag agtatactcg ctttgaatat attgaacgtt tagcaaacat ctatcatatt
     4741 atgaatgaac ctgtcaaaga atatcagtta ttggacaccg tcttgtcagt agcagaactg
     4801 attgcccttc ctgctggatt agaaaagaaa ctagtacgcc gccttttacg agtaaagcaa
     4861 caactatccg atcaagaaaa ataacttgcg tttttttagg aaagtgctat gattattttg
     4921 ttgaataaat gggatgtagc caaactggta aggcacttga ctctgaatca agcaattgta
     4981 ggttcgaacc ctgccatccc aatttgatgt gcttgctgaa aaaatgaacc ccctgtaaaa
     5041 gaacaatctt tttgcagggg gattattgta ttatttttac tacttgtatt tagtttacat
     5101 aattaaatta tgaataataa aatcgggcgt attcttaata caaaaactga tttacccaat
     5161 aattgctaat gctttctccg gaactttttc tctaggaact tcctcatacg tttctatgtg
     5221 tgctccttta ttgctaattt tcaaataatg attttctttt aacacagaaa gaccattaaa
     5281 ttcaaccgtt cgttctttcc cattggcatc agcagctttc tgcacatacc ttgctgtacc
     5341 atattcattt acttcctctg gtttttgtgt ctttacatag acctctcctt tttcaactaa
     5401 tggatttagc tgatcaagta taccagggat ttctccataa cttccttcag tataatattt
     5461 cagtccaaat agcaaaatac cactaatcgc cgccagtcca atcaaatatt taatcacttt
     5521 catctttcta cctccttgtt atatattcag tatatgggtc agttaaagaa attccatccg
     5581 tcccaagttg gagatttttc tcctacttta gaagcgagaa tcgagtgttt ttttagtaaa
     5641 aatgatcgtt atttgatatt attgacgtgt ggataaatca gtttttctcg ttttgtccat
     5701 gtaaaaaatc atgttgatag caaaggatgt gttcaaaatg aatcaagaag aattatttca
     5761 aaaagtcaag gaaatgatta agaacggcaa tttcgatggc gcaaaacgat ttatcgaaga
     5821 acataaagaa caattaggac cttataaaga gaaagcccaa aatcttttaa aagatgtaaa
     5881 tatcgacagt gtcaaaaaca aatttaaaaa tctattcaaa taagtaaaac tttcactttt
     5941 gtaaaatcaa aggaggacaa tgctgctgca tcgtcctcct ttggttcttt tggctctata
     6001 a
//
LOCUS       DACGMI010000105         5886 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.110, whole genome shotgun sequence.
ACCESSION   DACGMI010000105 DACGMI010000000
VERSION     DACGMI010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.110"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(76..1170)
                     /locus_tag="IXT46_002808"
     CDS             complement(76..1170)
                     /locus_tag="IXT46_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAQ4948682.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            1359..2120
                     /locus_tag="IXT46_002809"
     CDS             1359..2120
                     /locus_tag="IXT46_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4948683.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(2235..2675)
                     /gene="fabZ"
                     /locus_tag="IXT46_002810"
     CDS             complement(2235..2675)
                     /gene="fabZ"
                     /locus_tag="IXT46_002810"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAQ4948684.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            2895..3650
                     /gene="fabI"
                     /locus_tag="IXT46_002811"
     CDS             2895..3650
                     /gene="fabI"
                     /locus_tag="IXT46_002811"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAQ4948685.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(3760..4773)
                     /locus_tag="IXT46_002812"
     CDS             complement(3760..4773)
                     /locus_tag="IXT46_002812"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAQ4948686.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            4938..5858
                     /locus_tag="IXT46_002813"
     CDS             4938..5858
                     /locus_tag="IXT46_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAQ4948687.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
BASE COUNT         1789 a         1176 c         1054 g         1867 t
ORIGIN      
        1 cctataaaaa aacaaaataa aaaagcagaa ataactggct atttctagcg gattatttct
       61 gcaataacta attatctatt ttttattttc aattaattta aagcttgacc atggtttcaa
      121 aaagtcaagg aggaataatt cgtcatcgga gattcttcct acaacattga cacgtccgtc
      181 gtttttcata tccttcaagg cgatttgtgt ttctcctttg tattgaccgt acccttcatt
      241 gtcaatcagt acatccccat gatgcatatc tcgcgtatta tgaggcggga aatctttatc
      301 tttgtagtat acacgagtca tcgttgaacg aaggatatat tctgagcgat cccctcgata
      361 actatgaagg ttatcaaaca agcagattcg ttcgttttct gtaatacctt cttccgtatc
      421 tactttcaat gttggataat ccgcgttaaa tgcttctgcc atttctttca attcttcttc
      481 acttgcgtac gcatttccaa tagaaatatc atcaatcaat cctgtaagga ttaaatgctt
      541 cacttgtgtc gcaatttcaa gatctcggtg gtcttccagc gtgcacaagc catcttgcgt
      601 aggccaaggg ccaaactcag cagattgcga attgacgaat gccatcgtat tcaaattata
      661 ttttctgaat ttttctgaac aaaaaacaaa gtgttcgtat cctaaaccag agtatcgatg
      721 aggataaaaa ttatgagaac ctaataaatt atccgtgttt ggcgaataac tcatgatgtt
      781 gtcaacgtaa ttcgtgcccg aactcatatt gatctcgatt ttgataccaa aaggattgcg
      841 cgtcattttt gcttcttctg ctcctgtgaa tccgatatct aagcggaccc cgtaggcacc
      901 catcttatgg aaaaaagata agtcatcgta agaaatctcc aactgttcaa ataacgctgg
      961 attgatatca accattactt ccatgcctag gctattcgcg taatcaacta cttctttaaa
     1021 ttctgaaaga actttttctt tatcatcatt gatctgcagc aaactggtaa aaacccgttt
     1081 atacccatac ttatgagcta aatccaagta cgctttgtcc ttttcaaatg ttgaccgttc
     1141 tggataaatc gagattccta attttcccat attaccattt cctcctgcat cttttcgttt
     1201 ttgtatccac ttacattata gcaaacacaa agtaaatggt ctacaccttt tctttttctt
     1261 ttaaaataaa tgataaattc caataattta agtaggtatt ttccctctat tttgttatca
     1321 ttaaagataa caaaatagta aattggaaag gaacagttat gaagaaaaat aaagttattt
     1381 taagtattag tttagcagca gcattgctgt ttgctgctgg ttgttctgca aacaacacga
     1441 cttcttctag ttcgtctaca gaaagttcaa aaagtacatc tactgcggaa agcacgactg
     1501 ccagtagcgt cgatttgaac gcattggaat taccacaatt gacgaaagat gtcgccgaaa
     1561 atgaagatct ggtcgaaatg gtgacgaata aaggcacaat caaaatcaaa ttatttcccg
     1621 aacacgcacc aaaagcggtt gaaaacttta tgacacatgc aaaagacggt tactacaacg
     1681 gactgacttt ccatcgcgtc atcaaagatt tcatgatcca aggtggcgat cctaaaggcg
     1741 atggcactgg aggggaaagc atttggggag aaggatttga aacagagatc aacaaccacc
     1801 tttataatat aagaggtgcg ttatctatgg ctcgctcaca agatcctaac agtaacggca
     1861 gccagttctt tatcgttcaa aatacagatg atatgcatga tggtctttta aaagacgact
     1921 atcctcaagc aatcatcgac gcttataaaa acggcggtta tccttcacta gatggccatt
     1981 atactgtctt cggccaagtg attgaaggaa tggatgtcgt ggatgctatt gcaaatatcg
     2041 aaacagatag ttcagacaaa ccaaaagaag aagtaaaaat cgataaaatc aatatactgc
     2101 aagaagcaaa acaaaaataa aaaaataacg tctgaatcct gcatagatga caacgtatgc
     2161 taggattcag gcgtcttctt tttacataaa aagcaagtaa gcttcctttt gttttgctat
     2221 atcaggtttt atagtcaagc attttggttg acgatgaacg tgaactcgca ctcacagact
     2281 tttttatcat ctacatatgc tgcagataac gctgtaccga ctgatccctt cattttggtg
     2341 atttcaaaat gacatttcag cacatctcct ggaacaactt tttgacggaa tttggcctta
     2401 ttgatcccac cgatataagc tctttttcct agaaactctt ctgattttag gataagtatc
     2461 gaacctgctt gtgccagtgt ttctagaatc aacgcacccg gcatcactgg attgtcagga
     2521 aagtgacctt ggaaaaaatc ttcattgatt gttacatttt ttgtcgcaac gatctttttt
     2581 cctggttcta aagtatctac ataatcaata taacaaatag gataacgatt aggaatcaat
     2641 tccattactt cagtagcaga taatacgtaa gacataatta aactccttct ttcaggcaat
     2701 tgccattttc attactttga ctatcaaagt atcatattcc taaatattta gcaatctttt
     2761 tttaatttaa gaaaaaatag tttgacaatc aaaacatttt gactaataat taagaaatca
     2821 agaagttatt ttagctatta ttctctattt ttttacgact atcaaatttt tatcagaaac
     2881 aaaggagagt cattatgtca tttctagaag gaaaaaaaat cgtcattatg ggcgtcgcta
     2941 acaaaaaaag cattgcttgg ggttgtgctg aagcaatgtt gaaacaaggg gcagaaatta
     3001 tctatactta ccaaaatgaa cgaatgaaaa aatcattagt caaattggtc ggcgaagaag
     3061 cattcactgt agaatgtgat gtttctagcg acgaaagcat cgaaaaagca atgaatgcca
     3121 tcggtgaata tgctggggag atccacggcc ttgtccatgc agttgcttac gccaacaaag
     3181 aagaattgtc cggaaatgtg tctgatattt ccagagacgg ctatcaatta gctcaagata
     3241 tcagcagcta ctctttaatt gctgtatcaa aatacgcaca accgtttctt gcaccaaaca
     3301 gcgggatcgt tagcatgact tatctaggtt cagaacgcgc aatcccgaat tataacatga
     3361 tgggtattgc gaaagcttct cttgaagctg ctatccgtta tttggcagct gagttctcgc
     3421 ctaaaggaat tcgggtcaat ggaatctcag ctggggcaat caaaacatta gctgtcacag
     3481 gtgttaaaga ctatcaaaaa ctgatccagt tatctgaatc tcgtacgcct gatcagcaag
     3541 gtgtgacgat cgaagaagtc ggtaatgctt gtgctttctt aatcagccca ctttccagcg
     3601 gaatcatcgg tgatattatc tacgttgaca aaggtgtcca tctttcataa acttttgttg
     3661 cattctttaa agtaaaacat ataaaaatca ggaaaaaact ttttaaagtc tcttcctgat
     3721 tttttctttt tacgtttttt tcaactcatt actttgaaat tattccacga cttcaatcca
     3781 gccttctggt gcttctatgt ctccaaattg aatacctgtc aattcatcat acaaccgttt
     3841 tgttactggt cctacttccg tttcactata aaatacatga agattgttat tgtgataaat
     3901 cccaccgatt ggagaaataa cagccgctgt accacatgca ccagcttctg caaattgatc
     3961 tagatcatca atgaaaatat ctccttcaat tgcttgcagt cctagtcgtt cttcagctaa
     4021 ctgcaacaag gaatatttcg tgatacttgg taagatagag ggcgattgcg gagtgatgaa
     4081 ttttccgtct tttgtaattc caaagaaatt tgctgcacct acttcttcga ttttcgtatg
     4141 tgtggctgga tcaagataaa cacaatctga gtaatccagt tcttttgctt ctgttcctgg
     4201 aagtaaactc gctgcgtaat ttccgccgac ttttgctgca ccagtcccct taggagcagc
     4261 acgatcgtaa tcagatacaa taaaattcgt tggttttagt ccacctttga aatacgctcc
     4321 tactggcgta cagaagacga caaataaata ttctggagct ggatggacac caatgttttc
     4381 accgacccca atcagtaaag ggcgcaagta taatgtagcg cctgttccat agggcggcac
     4441 aaaatcttca tttgctttta ccacttgctt gacagcatca acgaacatct tttcagggac
     4501 cattggcatc agcaatcgtc tagcactttg attcatccgt cgactatttt gttcaggtcg
     4561 aaagagattg accttgccgt cttttcgacg ataagctttt agaccttcaa aacattgctg
     4621 accataatga agcgctggag agccttcatg aatcgtcagg taattatctt ctgtcaattc
     4681 tccttcttcc cattgtccgt ctttccattt ggcaataaaa cgccaaggag ttttgatata
     4741 agaaaaacct agattgttcc aatcgatttg catatactta ccaccttcgt tattttctcc
     4801 acattttatc attatccata ttatttgtca ttttattttc agcttttttc cttcattata
     4861 gttatttttg ctatttcctt ttttgaaaac ttcttggtac aatacagaaa gaatcaaatt
     4921 ttagaaaaga ggattttatg ttttcattat tagcaactgc cggtacgaca gactcttctg
     4981 gcgagacatt gacagatcaa gctgtcagca aagtaaatgc gtttcagcgg ttttgggacg
     5041 ggattgattg ggacgccatt ttggctgcct ttatccaaaa aagtttatat ctgatttttt
     5101 tgatcgtcct tttttggatt cttcaccgtg tgggaaaata tctgattgat aagtctttta
     5161 atcagtattc taaaaaagcc attctaaacg agagccgctt aaagacttta catagtcttt
     5221 taaatactat ttttcattat acccttggtt tcttttttat ctatgcaatt ttatctgcta
     5281 tcggtgtgcc gatcggatca cttttggctg gtgccggaat tgcaggtgtg gcaatcggtc
     5341 ttggtgccca agggttcatg agtgatgtta ttaccggatt ttttattatc atggaacaac
     5401 agatggatgt tggggactac atcaagctag caaacttaac gattgaagga accgtcgtat
     5461 ctgttggtat ccgtaccctt cagctgaaag caacggatgg tactgtccat ttcatcccga
     5521 atcgaaacat caccacgatc agcaatctct ctcgtgcaaa tatgcaagta cttttagata
     5581 ttcggattgt tcctgaagaa ggatatgaca aaatctatga gatcattgat cgagtaaatc
     5641 gtacattagc tgaaaaatac caagaagagc tccaaactga accttctatc tttggattag
     5701 tggatcttgg aaacagcaat tttgcgattc gtacggtctg ctacgcattg aacggaaaac
     5761 aatatgcctt aaaagaagag ttcttgagct cctatgtcaa agaattgaca gcttctggtt
     5821 tcacgattcc gaacagtcca attgctgtcg gaaaataatt tggacaaacg atgcaacgaa
     5881 tctcac
//
LOCUS       DACGMI010000106         5875 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.111, whole genome shotgun sequence.
ACCESSION   DACGMI010000106 DACGMI010000000
VERSION     DACGMI010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5875
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.111"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            642..1376
                     /locus_tag="IXT46_002814"
     CDS             642..1376
                     /locus_tag="IXT46_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4948688.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1392..2561
                     /locus_tag="IXT46_002815"
     CDS             1392..2561
                     /locus_tag="IXT46_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4948689.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2577..3572
                     /gene="lacD"
                     /locus_tag="IXT46_002816"
     CDS             2577..3572
                     /gene="lacD"
                     /locus_tag="IXT46_002816"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAQ4948690.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3651..4577
                     /locus_tag="IXT46_002817"
     CDS             3651..4577
                     /locus_tag="IXT46_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAQ4948691.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4596..5846
                     /locus_tag="IXT46_002818"
     CDS             4596..5846
                     /locus_tag="IXT46_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4948692.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1967 a          955 c         1203 g         1750 t
ORIGIN      
        1 agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt gactaaacga
       61 agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat tcagataaac
      121 tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc ttaagagaga
      181 acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat ttattctcat
      241 agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga tttgaaacca
      301 aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca ctggtaagta
      361 gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta aaaaaagata
      421 ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa aagttggaaa
      481 attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat attaacaaga
      541 ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa ataccactac
      601 tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat acctttcaat
      661 caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa aacagtatgg
      721 tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc gttagtcgca
      781 cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat cgacaacatg
      841 gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct ggcgcatata
      901 gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata ttggccttca
      961 agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta ggtgagcctt
     1021 tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc gagaaatcct
     1081 atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg aaacctttat
     1141 ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag gaattttatg
     1201 ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga tcaccagtgc
     1261 tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt acattaagtg
     1321 tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact aactgaattg
     1381 gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga gcagaaaata
     1441 ctacccgaga aattcgacag caaccggaac tgtggcatga gacgtttgac cgttatcaag
     1501 aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct ggagagcgac
     1561 caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat acactaattc
     1621 cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt ggttcgaccg
     1681 atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc ttggtctcat
     1741 ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc aatcagctgg
     1801 tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg gctacacaaa
     1861 tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat gacgctggtt
     1921 ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt tttgatcaag
     1981 caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga gaagaagtca
     2041 tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc atcatttact
     2101 taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt ctcgagttaa
     2161 ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat ggtcccaaat
     2221 cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca tatacgcaga
     2281 aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa cgcgttgttg
     2341 gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt gcagattcgt
     2401 tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg atcgcattac
     2461 tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga acagtcaatc
     2521 gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg tgaagcatgt
     2581 tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca gaaggcatta
     2641 ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg gctttaggga
     2701 tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa gaattgactc
     2761 cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca cagaagcgtg
     2821 cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa accgtacccg
     2881 gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag ttaggtgcgg
     2941 atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc aatcggcaaa
     3001 agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg ccattttatt
     3061 tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc tatgccaaag
     3121 caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag tataaagtag
     3181 atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat gcaacagggg
     3241 agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc gatgcaacag
     3301 atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg gagacattgc
     3361 gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga gcaacttgga
     3421 aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa tggctgacag
     3481 aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact gccatcccat
     3541 ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt agtgataaga
     3601 gatatgtgtg attataattt atcattattg aaactgggag gatattttat atgaataaaa
     3661 gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa ttaaagcagg
     3721 caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt agctgtcctt
     3781 acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct gatttaattt
     3841 tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta actctaaaag
     3901 agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta aatttagaac
     3961 ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt ggtagaatcg
     4021 tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt tgtttaactg
     4081 gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca ttatccaaat
     4141 caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt gatgaaccaa
     4201 ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt ttattagttc
     4261 ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc gttgattata
     4321 taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta acggctaatg
     4381 gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta gcatcaaaag
     4441 catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt cttccagaaa
     4501 atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt atgttaggaa
     4561 aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt caaaaaatag
     4621 ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg gctgcagtta
     4681 tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg atagaaggat
     4741 ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca tcagattcaa
     4801 catttggtat tattggatta gctgttacct actctttggg acacaatcta gcaaagactt
     4861 atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt ttacttacac
     4921 ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt acctcgggtc
     4981 tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg tttgtactta
     5041 aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga gctttcgttg
     5101 ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta atttgttata
     5161 aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa ccactatctt
     5221 tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt ttcttttgga
     5281 tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta ttattgcaaa
     5341 actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac attataactt
     5401 atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt gcacttgcca
     5461 ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag ttatcaatcg
     5521 ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact atattaaata
     5581 taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt acttattttt
     5641 caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg acaactccac
     5701 cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg attcaagtaa
     5761 taacaattgc aataaatgtt ttgatatact atccattctt taaattagat gataatgcca
     5821 agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt agtta
//
LOCUS       DACGMI010000107         5856 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.112, whole genome shotgun sequence.
ACCESSION   DACGMI010000107 DACGMI010000000
VERSION     DACGMI010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.112"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(44..2968)
                     /locus_tag="IXT46_002819"
     CDS             complement(44..2968)
                     /locus_tag="IXT46_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HAQ4948693.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SE"
     gene            3114..3689
                     /locus_tag="IXT46_002820"
     CDS             3114..3689
                     /locus_tag="IXT46_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016204422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4948694.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3903..4598
                     /gene="vanR"
                     /locus_tag="IXT46_002821"
     CDS             3903..4598
                     /gene="vanR"
                     /locus_tag="IXT46_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAQ4948695.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4576..5727
                     /locus_tag="IXT46_002822"
     CDS             4576..5727
                     /locus_tag="IXT46_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4948696.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPGFCCKVLNKE"
     gene            complement(5750..>5856)
                     /locus_tag="IXT46_002823"
     CDS             complement(5750..>5856)
                     /locus_tag="IXT46_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAQ4948697.1"
                     /translation="MEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT         1802 a         1110 c         1107 g         1837 t
ORIGIN      
        1 aaaatacttt gtttttttac ctgtctactt gacagggggc agttcactct gagttaaaat
       61 ggtattctcc tagtaaatta atatgttccc aacctaaggg cgacatatgg tgtaacaaat
      121 cttcattaaa gctacctgtc cgttttttat attcaactgc tgttgttagg tggagagtat
      181 tccaaatact tatagcattg ataattatgt ttaaagcact ggctctttgc aattgatgct
      241 gtatggtgcg ttctctaagc tcaccttgtt ttccgaagaa aatagctctt gccaatccat
      301 tcatggcttc tcctttattc aatcctcttt gtatttttct tcttaatgat tcatccgata
      361 tataattcaa aataaagatc gttttttcta ttcggcccat ctcacgtaag gctgtagcta
      421 agctgttttg tcttgaatag gaacctagct tccccataat aagggatgct gaaactgttc
      481 cctcccttat agaatgagct aatcgcaaaa catcctcata attttcttta atgacctttg
      541 tatttatttg tccacgtaaa atggcttcta gttttggata ctcacttgct ttatctatcg
      601 taaataattt tgagtccgat aaatccctta ttcttggggc aaatttaaat cctaataaat
      661 gagtcagtcc gaatatttgg tcagtgtaac cggcagtgtc tgtataatgt tcctctatgt
      721 ttagatccgt ctcatgatgt aacaaaccat ccaaaacatg aatcgcatct cttgaattag
      781 tatgaataat ctttgtgtag taagaagaga attgatcact tgtaaatcgg tagatggtgg
      841 ctccttttcc agttccataa tgtggatttg catctgcatg tagtgatgaa acacctagct
      901 gcattctcat accatctgac gaagatgttg taccgtcgcc ccaatagaaa ggcaattgta
      961 atttatgatg aaagtttact aatatggctt gggctttatt catggcatct tcatacatgc
     1021 gccattgaga tacattggct agttgcttat atgtaagtcc gggtgtggct tcggccatct
     1081 tgctcaagcc aatattcatt cccattccta aaagggcagc catgataatg attgtttctt
     1141 ccttatctgg ttttcgatta ttggaagcat gagtgaattg ctcatgaaat cctgttatat
     1201 gggccacatc catgagtaaa tcagttaatt ttattcttgg tagcatctga taaaggcttg
     1261 cactaaattt ttttgcttct tctggaacat ctttttctaa gcgtgcaagt gatagctttc
     1321 ctttttcaag agaaacccca tctaacttat tggaattggc agctaaccac tttaaccttt
     1381 cattaaagct gctggttctc tccgttatat aatcttcgaa tgataaacta actgataatc
     1441 tcgtattccc cttcgattga ttccatgtat cttccgaaaa caaatattcc tcaaaatccc
     1501 tatattgtct gctgccaaca atggaaacat ctcctgcccg aacatgctcc cgaagttctg
     1561 ttaaaacagc catttcatag taatgacgat taattgttgt accatcatcc tcgtataaat
     1621 gtcttttcca tcgttttgaa ataaaatcca caggtgagtc atcaggcact tttcgctttc
     1681 cagattcgtt cattcctcgg ataatctcaa cagcttgtaa aagtggctca tttgcctttg
     1741 tagaatgaaa ttccaatact cttaatagcg ttggcgtata ttttcttagt gaataaaacc
     1801 gtttttgcag taagtctaaa taatcatagt cggcaggacg tgcaagttcc tgagcctctt
     1861 ctactgaaga gacaaaggta ttccattcaa taaccgattc taaaacctta aaaacgtcta
     1921 atttttcctc tcttgcttta attaatgctt gtccgatgtt cgtaaagtgt ataactttct
     1981 catttagctt tttaccgttt tgtttctgga tttcctcttg agccttacga ccttttgata
     2041 acaaactaag tatttgccta tcatgaattt caaacgcttt atccgttagc tcctgagtaa
     2101 gttgtaataa atagatggtt aatatcgaat aacgtttatt ttcttgaaag tcacggaatg
     2161 catacggctc gtatcttgag cctaagcgag acagctgcaa caggcggtta cggtgcaaat
     2221 gactaatttg cactgtttct aaatccattc ctcgtatgta ttcgagtcgt tctattattt
     2281 ttagaaaagt ttcgggtgaa ggatgacccg gtggctcttt taaccaaccc aatatcgttt
     2341 tattggattc ggatggatgc tgcgaggtaa taatcccttc aagcttttct ttttgctcat
     2401 ttgttagaga tttactaacc gtattaaata gcttcttttc agccattgcc cttgcttccc
     2461 acaccattct ttcaagtgta gtgatagcag gcagtataat tttgtttttt cttagaaaat
     2521 ctatgcattc atgcagtaga tgaatggcat caccattttc caaagctaat tgatgaaggt
     2581 acttaaatgt cattcgatat tcactcaggg taaaagttac aaagtcgtat tcacttcgaa
     2641 tttctttcaa atgatcccaa agtgtatttt ccctttgagg ataatgatca agcgaggatg
     2701 gactaacacc aatctgtttc gatatatatt gtatgaccga atctgggatg cttttgatat
     2761 gagtgtatgg ccaaccggga taccgaagaa cagctaattg aacagcaaat cctaaacggt
     2821 tttcttccct ccttcgctta ttaactattt ctaaatcccg tttggaaaaa gtgaagtagg
     2881 tccccagtat ccattcatct tcagggattt gcataaaagc ctgtctctgt tccggtgtaa
     2941 gcaattctct acctctcgca attttcattc agtatcattc catttctgta ttttcaattt
     3001 attagttcaa ttatatatca atagagtgta ctctattgat acaaatgtag tagactgata
     3061 aaatcatagt taagagcgtc tcataagact tgtctcaaaa atgaggtgat attttgcgga
     3121 aaatcggtta tattcgtgtc agttcgacta accagaatcc ttcaagacaa tttcagcagt
     3181 tgaacgagat cggaatggat attatatatg aagagaaagt ttcaggagca acaaaggatc
     3241 gcgagcaact tcaaaaagtg ttagacgatt tacaggaaga tgacatcatt tatgttacag
     3301 acttaactcg aatcactcgt agtacacaag atctatttga attaatcgat aacatacgag
     3361 ataaaaaggc aagtttaaaa tcactaaaag atacatggct tgatttatca gaagataatc
     3421 catacagcca attcttaatt actgtaatgg ctggtgttaa ccaattagag cgagatctta
     3481 ttcggatgag acaacgtgaa gggattgaat tggctaagaa agaaggaaag tttaaaggtc
     3541 gattaaagaa gtatcataaa aatcacgcag gaatgaatta tgcggtaaag ctatataaag
     3601 aaggaaatat gactgtaaat caaatttgtg aaattactaa tgtatctagg gcttcattat
     3661 acaggaaatt atcagaagtg aataattagc cattctgtat tccgctaatg ggcaatattt
     3721 ttaaagaaga aaaggaaact ataaaatatt aacagcctcc tagcgatgcc gaaaagccct
     3781 ttgataaaaa aagaatcatc atcttaagaa attcttagtc atttattatg taaatgctta
     3841 taaattcggc cctataatct gataaattat taagggcaaa cttatgtgaa agggtgataa
     3901 ctatgagcga taaaatactt attgtggatg atgaacatga aattgccgat ttggttgaat
     3961 tatacttaaa aaacgagaat tatacggttt tcaaatacta taccgccaaa gaagcattgg
     4021 aatgtataga caagtctgag attgaccttg ccatattgga catcatgctt cccggcacaa
     4081 gcggccttac tatctgtcaa aaaataaggg acaagcacac ctatccgatt atcatgctga
     4141 ccgggaaaga tacagaggta gataaaatta cagggttaac aatcggcgcg gatgattata
     4201 taacgaagcc ctttcgccca ctggagttaa ttgctcgggt aaaggcccag ttgcgccgat
     4261 acaaaaaatt cagtggagta aaggagcaga acgaaaatgt tatcgtccac tccggccttg
     4321 tcattaatgt taacacccat gagtgttatc tgaacgagaa gcagttatcc cttactccca
     4381 ccgagttttc aatactgcga atcctctgtg aaaacaaggg gaatgtggtt agctccgagc
     4441 tgctatttca tgagatatgg ggcgacgaat atttcagcaa gagcaacaac accatcaccg
     4501 tgcatatccg gcatttgcgc gaaaaaatga acgacaccat tgataatccg aaatatataa
     4561 aaacggtatg gggggttggt tataaaattg aaaaataaaa aaaacgacta ttccaaacta
     4621 gaacgaaaac tttacatgta tatcgttgca attgttgtgg tagcaattgt attcgtgttg
     4681 tatattcgtt caatgatccg agggaaactt ggggattgga tcttaagtat tttggaaaac
     4741 aaatatgact taaatcacct ggacgcgatg aaattatatc aatattccat acggaacaat
     4801 atagatatct ttatttatgt ggcgattgtc attagtattc ttattctatg tcgcgtcatg
     4861 ctttcaaaat tcgcaaaata ctttgacgag ataaataccg gcattgatgt acttattcag
     4921 aacgaagata aacaaattga gctttctgcg gaaatggatg ttatggaaca aaagctcaac
     4981 acattaaaac ggactctgga aaagcgagag caggatgcaa agctggccga acaaagaaaa
     5041 aatgacgttg ttatgtactt ggcgcacgat attaaaacgc cccttacatc cattatcggt
     5101 tatttgagcc tgcttgacga ggctccagac atgccggtag atcaaaaggc aaagtatgtg
     5161 catatcacgt tggacaaagc gtatcgactc gaacagctaa tcgacgagtt ttttgagatt
     5221 acacggtata acctacaaac gataacgcta acaaaaacgc acatagacct atactatatg
     5281 ctggtgcaga tgaccgatga attttatcct cagctttccg cacatggaaa acaggcggtt
     5341 attcacgccc ccgaggatct gaccgtgtcc ggcgaccctg ataaactcgc gagagtcttt
     5401 aacaacattt tgaaaaacgc cgctgcatac agtgaggata acagcatcat tgacattacc
     5461 gcgggcctct ccggggatgt ggtgtcaatc gaattcaaga acactggaag catcccaaaa
     5521 gataagctag ctgccatatt tgaaaagttc tataggctgg acaatgctcg ttcttccgat
     5581 acgggtggcg cgggacttgg attggcgatt gcaaaagaaa ttattgttca gcatggaggg
     5641 cagatttacg cggaaagcaa tgataactat acgacgttta gggtagagct tccagggttc
     5701 tgttgcaaag ttttaaataa agaataaaat cccttacggt atctatgatt taagctggga
     5761 ttcccaataa taccttgatt tcagtacaga ccgaaaaccc gaagagagtg ccttcttttc
     5821 gggttttctt atataatcct cgaatggctt ccatgc
//
LOCUS       DACGMI010000108         5765 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.114, whole genome shotgun sequence.
ACCESSION   DACGMI010000108 DACGMI010000000
VERSION     DACGMI010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.114"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(1020..1418)
                     /locus_tag="IXT46_002824"
     CDS             complement(1020..1418)
                     /locus_tag="IXT46_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948698.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KIAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1634..2689
                     /locus_tag="IXT46_002825"
     CDS             1634..2689
                     /locus_tag="IXT46_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HAQ4948699.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTANLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2709..3062
                     /locus_tag="IXT46_002826"
     CDS             2709..3062
                     /locus_tag="IXT46_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948700.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQAHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3244..3540)
                     /locus_tag="IXT46_002827"
     CDS             complement(3244..3540)
                     /locus_tag="IXT46_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948701.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3544..4362)
                     /locus_tag="IXT46_002828"
     CDS             complement(3544..4362)
                     /locus_tag="IXT46_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4948702.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4588..4809
                     /locus_tag="IXT46_002829"
     CDS             4588..4809
                     /locus_tag="IXT46_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HAQ4948703.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKQLMKEHEENDQSISHEDMLKELGL"
     gene            4811..5077
                     /locus_tag="IXT46_002830"
     CDS             4811..5077
                     /locus_tag="IXT46_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4948704.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            5190..5729
                     /locus_tag="IXT46_002831"
     CDS             5190..5729
                     /locus_tag="IXT46_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948705.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGDYSSANEVIEEKKGYAKNGLE
                     IVGTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKLQLDRIKEESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVT"
BASE COUNT         2036 a          953 c          860 g         1916 t
ORIGIN      
        1 ttacctattc ccaaaatcca tttattcgtt atttttttca ctgattaaga ataattattt
       61 gatgcttaaa ttagctaaaa aagcgatttg ttactgatat aatcatgata ttgcagctga
      121 attaggcgga aagataaaat gttcgcaaaa tcaaagtatc aattatcttg tttttttata
      181 aatttgtaag taaaaatcta aaaaagtttt cttttaattg gtatatgtat taaaatcaca
      241 tttaatcacc cataaagtat gcgctttcat ttttttggat gagtttaata tcaataaata
      301 acgatgtaaa aatcatttat tatgctcttt tataaggata ttaattgatc taatttgaaa
      361 aaaatcaaaa tttaaatgtt ttaatattac aaataaaatc atgttattgt aaaatggtat
      421 aaaaaagcta aatattctat ttttgttatt ttattagcag gaaaatttaa atagttttac
      481 aagaatccgt agaaatatat tggttttgcc ttcagattaa tactggatca tattaatctg
      541 aatataatat atgaactaat aaatagctta acctcgctat tttgtttttt ctgatcacta
      601 tctatacagc attagtaaat agaattttaa aaataaaaaa attaagacaa aaaagtatca
      661 acataaacat atacatatac acgtttatgt tgattcactt aatttgtcct ttaaaaagca
      721 cttattttaa tataatgtta ttttataatc ttattacaag ctgattgtta ggcgttgtcc
      781 tttcattaca tttattaacg gttattttat tgtttaattt attaattatt tttgatctaa
      841 aacttagctt aacaaataaa taattaacca accgccagat aaaaatgcga tcattgctaa
      901 tacataagca aagataaaaa tatgttcgat cagcttaaac cctgatgcga ttaagcagac
      961 caagtaaaat agaaattctc ttacagataa tggtaatttt ctaactagca tactcataat
     1021 taacacccca aagtaatatt gtattttgaa cattttacat ccaatacagc atcaatcaac
     1081 cattgccaat caaaaataca aggcttcatt gaagtatgtt tttcagatga aaagatataa
     1141 tataatttct tcggaataat attttcagtt gttgggatca agctaaatct aataccgtct
     1201 aactcatagc taccagcttt ctctccatta aaaatttcct tagcactttc ttctaaagaa
     1261 tcaaaatatt tttcgacagc aatctttgaa gcttttacta ttgaagcatt tcccttttcg
     1321 ataaaatctg cttttgtttt accgacaata agtaattctt gatcagtaaa atcttctaaa
     1381 ataatggtag tgtaattctt atttcttctc aatcgcatca ggatcactcc ttaatataat
     1441 ttatgttttt ataatatcat aataagataa atttgcaagc atttatttac acctttttat
     1501 ttacacttta ttataattaa ttagactttt atgattgcat ttttttctta taaacagttg
     1561 caactaatag taaataggtg taaactattt tcgtaccgaa ataccataaa cacaaacaga
     1621 aagaggtcat accatgaaag aaccattatt gttttccgtt gacttaggga ataaatcagt
     1681 aaaagaaatg agtacacacg tttctccact ctcacttccc tctcgtattt tgaacaaaaa
     1741 tatcattaat tcaggacgtt tttctaatat aggttcctca ttaaaacgat cactaaacgt
     1801 ttctgaatat agcctagtaa acactactga aagctattac tttgggaagg atatacacga
     1861 gctaggaaaa gatgactacg tgatagaatc actaggtttt gggatcagca gatacaagca
     1921 ggaaacctac caaaatatcc tatctttctc tttagctaac ctagcacgtt tagaagatca
     1981 atctgatgac gttttaaccg ctaatctagt tttaggtctg ccttcatccg actataccga
     2041 aacaatcgtc aaatacgtga tgcaacaagc cacacgacaa cattcagttg aagttgacgg
     2101 taaagcttat aatataaacg tagataccgt ttgggtactg ccacagccga ttggaacact
     2161 atataacctc ctacttgctg atgatggtag tgtacaagat gaaacattga tcagtcagaa
     2221 gatcggtttt gttgatattg gtggtggcac gaaacttttt gatgttgtcc aaaattttga
     2281 aattgacgaa aacaaccgtg aacaaaagga taccggtatt tttactttat ataatcgtat
     2341 cgtaaatatg cttgaccttc cgatcagtcc taatgctttc caacttgaaa agattatccg
     2401 agaaggcaaa gaaaaaggcg tatatctatt taaaccaagc ggaaatgaaa gttttgatat
     2461 ttcagaagta gttgaaagag aaataaaaac atacaccaat atggttgttg cagaagtttt
     2521 agctacattc aaaaacttca caaccttaga taaagttgtc tttactggtg gtggggcttc
     2581 tattatcgac aaacaacttg taaaagataa aattccgcat accttgtttg ttgaagacag
     2641 tgaattttct aatgtaaaag gcttttacaa gtttggttta actcaataaa acagcgaagg
     2701 agatcaacat gaataaggga aaatcagagc gttatgtagt tataatcaat agagaaaagg
     2761 ttagcgagtt acctttagca gagtttcttg aatctgaata tgaaacacta ggcgttaaat
     2821 actctcagac gatcaaaaaa gctttgaatc tatatcggcg tgtaaagaac aatgaagtta
     2881 caattattga agcaggcaac gatagaaacg atagcaaagt agctgaagta aagaataaac
     2941 caactgatca taaccctatt caacaagcgc atccttcaac ggttacatcc gatcattcag
     3001 caaagaaaga aaagccaatg ctaaaagggt tcaatgcacc aagtaacaaa gacttacttt
     3061 aaaaataaaa aggcgaggtt acaataccta gcctttttat tatgtacaaa tacaaacata
     3121 aacatatacg tatacatgta tataaacatg tatacgtata tatccataaa cacgtatacg
     3181 aaatttagtt aagctatacc taaccgctta ttccaataaa aaaagtgatc agctttaaac
     3241 tgatcactca ccaaaaactt catcatacaa gttatctatc atttcaccaa gtaaagctga
     3301 atctgatcga attcctaact tttcgctgat tttagatagt ttctttcttt gtgatggttg
     3361 aagcgtgaat tgataatttt tcttcttttc agaactatca ctttttagtt tagctaccaa
     3421 agaacttgtt gtttctttag gtgtttgttt aggttcttca actgcttcaa ccacttcagg
     3481 aacttcttct acttcagctt cagcgaattt tttaaatcta ttttctttca cttcaatcac
     3541 tccttattct tgtgccgtat caattatttt gttgtatagc gtaaacgtgc tttcaaagaa
     3601 atccttattc ttacgataga tattcttatc cttagcgaac tcagcaatat tcttaccttc
     3661 taagctagtt gcattaagca attccttctc ttgtacatat ccaagataat tagataacgt
     3721 tggtaccaat tctaggaact cacgacttga attagtatta tgtttgatcc tgctaccgat
     3781 cgtagcgtat ttagtttcca tcagtgtttc accagtctta atatcaatca actgttttgc
     3841 tagtgcatca atatctttac caagcttaag caaagcttca aaaccatctt tagatggatc
     3901 agaaatgcct acgacaagat cagatacagc ccaagcattt tgagctagta gacctgcatc
     3961 attatgagta tcaatcagaa ttagatcata cttctcttta agctgttcat agttaacaac
     4021 gatccatcta aacagtaggg ttctgttgtt aggcatatca cgcatttgca tctcaacttg
     4081 ttttaaatct tcacctgcta ctaaaatatc catgttctca tttatagcta aaggttcagc
     4141 tgatccatga agatataaat gattgattgt attctctctt ttcgctttac tgaaagcatc
     4201 aggaaatcgt tttgataggt tttgcgactt atcttcatca atatacagca ccttcatacc
     4261 taaattttcg acagcatatc cacctagatt gtagattgtt gttgttttac ctgttccacc
     4321 tttttcaatg tttccagtaa tgattgacaa cttcttttcc atgattaaac ctcccttatt
     4381 aatcttttgt aactccatta tacactataa acacgtttat gtatatattt atatacataa
     4441 acgtgtttat atttatattt gcttttatat tctacaacat aaacatatat atgtatatgt
     4501 ttatgtttat gtatatattc aaatatataa ctattgcatt tgtcatacaa tcgtagtaca
     4561 atgtaattga aaaggagttg ataaactatg ccagtaataa gtattcgtgt atctaaagaa
     4621 gaaaaagatt ttcttgaaaa agttgctgaa ttcaacggag ataacatttc tgaatttatg
     4681 cgtagtaatt ccctgcaaac agcagaaacg ttagtagact ttgccaccta caagcaacta
     4741 atgaaagagc atgaggaaaa cgatcaaagt atttcccacg aagatatgct aaaagagtta
     4801 ggcttataag atgacttacc aagtaagata tgaacgtgaa gctcaaaaag cgctaaaaaa
     4861 aatggataag tttcaggcaa aggttatcct aaactggatc gagaaaaatc ttgtaggcac
     4921 tgatgatcca agaaagcatg gtaaaggtct aacagctaat aaatcaggct actggcgata
     4981 tagggtaggt gcataccgta taatagctga tattagcgag catgaagtga caattcttat
     5041 attgtctatt ggtcacagaa gtgaagttta taagtaacag acaagctgat aaggcttgtc
     5101 tgtttttttg ttaacccaac aaaatcactg tttacgatcc cactttacct aaaaaagaac
     5161 aatatcctct tgatattata cacaccagtg tgtataatat aagtgtaaac aagctaatta
     5221 actttcaaaa ggagcgattt tttatgggat ggtatggtga ttattcatca gcaaatgaag
     5281 tgatcgaaga aaagaaaggg tacgccaaaa atggtttgga aatcgtaggt accaaagtaa
     5341 cgaagaccta tggaattatc cttttcaaag atgcagaagg aacctacgat attgacagct
     5401 tcatctttcg agatgaaatg tacaaaccaa tctacttctt aaatgacagt cctgcttact
     5461 ttaagaaaat tccgaaaaaa tggttgaaat tctttgtcgg tgatcaagaa aaaatggtta
     5521 agctacaact agatagaatt aaagaagaaa gcaataaacc aaaacttgat gacttattag
     5581 ttgcaggtaa aacttactca atctgggatg gatcgtatgt cgctgtctat cagtataaac
     5641 tcaaacgtag ctttattttt cgactacaag atggatcact cactcggttc actcgactat
     5701 cagcaggaga tgttaaggaa gtaacctaaa acttaaatac ataaacataa acgtgtatac
     5761 gttta
//
LOCUS       DACGMI010000109         5722 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.115, whole genome shotgun sequence.
ACCESSION   DACGMI010000109 DACGMI010000000
VERSION     DACGMI010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.115"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            191..916
                     /locus_tag="IXT46_002832"
     CDS             191..916
                     /locus_tag="IXT46_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948706.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            906..1415
                     /locus_tag="IXT46_002833"
     CDS             906..1415
                     /locus_tag="IXT46_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948707.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1485..2933)
                     /locus_tag="IXT46_002834"
     CDS             complement(1485..2933)
                     /locus_tag="IXT46_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4948708.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2933..3649)
                     /locus_tag="IXT46_002835"
     CDS             complement(2933..3649)
                     /locus_tag="IXT46_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4948709.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3630..3980)
                     /locus_tag="IXT46_002836"
     CDS             complement(3630..3980)
                     /locus_tag="IXT46_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAQ4948710.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4124..4897
                     /locus_tag="IXT46_002837"
     CDS             4124..4897
                     /locus_tag="IXT46_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4948711.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5068..5434
                     /gene="ssrA"
                     /locus_tag="IXT46_002838"
     tmRNA           5068..5434
                     /gene="ssrA"
                     /locus_tag="IXT46_002838"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         1658 a         1124 c          994 g         1946 t
ORIGIN      
        1 tattgtcgct gctcctcttt tcgaataaac agtgttcaaa agcttgcatc tacggtaata
       61 gaatagggca gcttcttcac aacctcttgc tttttacaaa atattttctg gttttaattc
      121 gtgatttcac taaaggaatt tcatacttta ttcatattca ttttctatac tttttataga
      181 ggtgaaaagt atgaaaataa tccgctatgc tactgctcga ttaatttatt acaaaaagca
      241 gacaatactc tattgtttat tttcaagctt ttctgctttt ttattgatag catgcctgac
      301 tctttaccat tcgcaatcgg ctttagccaa tcaagtccaa gatcggcttt catttattgg
      361 cgcttctgca tctacagagc ttcttccggc tttagaatta gctagccgat tttatataaa
      421 aggcatattc agtttatttt ttctatttgc cttccttttt atctttttct tttactattc
      481 agtcaggcaa aacaagcagg aattgatcaa ttggcgcctg actggtcttt ctaaaaccaa
      541 attattcctt tttattttct ggcagctgtt ctttcctctc tttctttgtt gtatcttggt
      601 tttattgtgg atcgtcagct tccagtcagt ttatgaagcg cttcttcaaa ggatcaattt
      661 tcttgtctta aagactactg aactgccaga tatccgtgat atcttgactt cggtaagcgg
      721 acttacaatt ccgatggatc aacagacttt ttttaccatc gatttccaaa atgatctttt
      781 tttcacagat atacttaagg gatttgccca aactcttatt gggctcagtg gatgctgtct
      841 cattcttagt ctattccctt tcactttttt tatccatcat ttgcaaagta ggaggcctgg
      901 acgtaatgaa acctgaatat ttgattcatg ctgaacactt gaccgttatt ttgtgtcctc
      961 tcgaaaaaca gcataaaata ttggagcact tgaaaaaaga ggttcttgtt gcaaaactgg
     1021 ataattttgc gatcatccaa aaaaattggc cgatgtttcc ttatctgaat cttaaagacc
     1081 atgtcctgtt ggatgtaccg gaaaaagaaa tcaaacaaga tcgtttggcc tatcaagaaa
     1141 aacttgatat ctctccttcc ttgcttaatt gtgcggcagc tgagttgacg tcttttgaaa
     1201 aagtaaagct gcaattactt catgccttgc tttccaagcg aaacaatatt gttattgaag
     1261 atacatttga tgaacttagt gtattggaga tccaagagct actccacttg ctttcttatt
     1321 tagctcatga agaaaatcaa ggtatcttac tctttactca tgatgctact attgctcaaa
     1381 gtccttatat tgatcgttta gagcccgcgg gctaaatcaa tcattttata gtaaaaacaa
     1441 gcggtataga agatcgattc atgatctttt ataccgcttg ttttttactc ttttttgatt
     1501 tctacgtcag gcaaacgaac agcgaatttt gttccttttc ctagttcgct ttctacttct
     1561 aattttcctt tatgcaagcg tacaagttgc tgcacgattg gtaaacctaa tcctgattca
     1621 ccatattttg tattttttct tgaaggatct actttataat aacgatccca gatacttttc
     1681 atttgttgtt cagacattcc aattcccgta tcttcaatcg tgatgatcgt ttcaagatag
     1741 cctttttcta aagtaatcgt gatttggccg ttttcagtaa actgtatcgc gttttgaata
     1801 atattgacca tgatttggac aaatcggtca taatcagcgt aaacatcaat atcatcaacg
     1861 gctttcaatg tcaatgtatc tcctgctgct tctgctttag cttctaactg tgcaacaata
     1921 tttttcaatg tttctgttcc attgaatttt ttaatgacca tactgatttg attcgtacgg
     1981 attttttcat aatccaagtt ttcattcacc aaacggatca gacgctctgt ttcatttttc
     2041 atcaatttaa tcgcgttttc tcgctgattt tcagggattg cattgtattc taacccttcc
     2101 agaagtccgt tgattgtcgt aagaggtgtt ctcatctcgt gagaagcatc tgccataaat
     2161 tgtcttcgac gattttcttg ttcttcaatt tctgcttgag attctttcaa tgaattcgtc
     2221 attttattga aatcatctgc taactcatca aattcatctt tgtcatgtac ggggagctgt
     2281 acatcaaaat taccattcgt cacttctttc gtcgcattcc ttaaccgatt gatacgctta
     2341 acttggaatg ctgcaaaagc atagctggca ataactgcaa cgatactgga aaaaataaat
     2401 cctttgaaca ggttcagtgt aattggacga acgctgttat cgatatttcg cgcaggttga
     2461 ctaactacaa gtgctccata gaattcatga ttcaaattaa atggcacaag tgcgtaagag
     2521 gtcgcctgtg cttgtcctaa aatattttta ttcgatgtga atttttcttg acgtccattc
     2581 ctcagatttt tccattgatc agctgttaag gtaaaattca gtaaagctgt attagtcgga
     2641 taaatgacac gttcgttttt atcgataaat ataaagttca cattttgttc tgtcagtact
     2701 tgctctgtca gcagcaatgc attttgaaac gcctgatctt gactaaactg cgggagcgta
     2761 tcggcatagg tttgcgttgt cttttcaact gattcagcat atccaaacag ttgctggtaa
     2821 ttgttttctt caatcgtttg ttttgtcagt tgtgtaaaag aaactccaac gatcaataag
     2881 atcaacgcga ccattccgca aaaagctaag agttgctgat acaaataacg cattaggcaa
     2941 caccagaatc atcgaatttg tagccgactc cccaaacagt ttggatgact tgtggtccga
     3001 ccttttcgat tttttgtcgt aatttcttga tatgggcgtc cactgtccgt tcatcaccaa
     3061 agtactgata atcccagact aattcaagca actgctcccg agagaatact tgacgtggtt
     3121 tttttgctaa agtaaacaat agatcgaact ctttaggcgt cagtccttca attggccggt
     3181 tgtccagata cgcttctcgt gttttcgtat tcatcttgaa atgactagtc tcgatatcaa
     3241 aatgatcatc tgaaactgct gcttcttctc ttgcttctgc caactcacta cggcgatgca
     3301 aagctttcat tcgagcaata agcgtcagag gactgaaagg ttttgtgaca taatcatctg
     3361 cccccatctc taagccgatc acctgatcgc tttcagaatc tctagctgtc agcatgataa
     3421 tcggcacagt acttgaaact ttgcggatct ctcttcctac tagcataccg tccagtgtgg
     3481 gcaaattcag gtctagtgta atcatatccc aatgttgtgg gttttctaaa aaggcatcga
     3541 gcccttcttt tccatcatac ttgaaagttg cttcccaacc ttcatttaag aaaaacatct
     3601 gcatcatttc agaaacagat tgattatctt caatcattaa aatattcatt atcgttccct
     3661 ccagtttcca ggtcatattt ctgtaatttc ttttctgtca taataaaaat aggcataatt
     3721 ggaaatacta gcagaagcat ttcaatcaga aaataattcg tatgcccaga tgtctttaaa
     3781 taatagccga tcaatgccat cagtaagccc ataagaaaaa accagtttcc gcttgtcttt
     3841 tgagccagcc gccaatgagc gtctgttttt gcggcaagag gcgaatgata cccataaaaa
     3901 ggcagatttc cttttgaggg cagaatccga aaaagactgc caattattaa gaataagata
     3961 ccaatactga aaaaaatcat tctttccctc ctaaattctc ttcttatagt atactctaaa
     4021 ttgttgactg aaccaatatg ttcaggaatt cttcacgaaa ggtttgtctt ttgttcattc
     4081 tttgttaaga taaacttatt ccaataaaaa aggagtttta tttgtgtcaa attatcgtgc
     4141 aatcactttc tttgatcttg atggaacatt actagatgcg aaatcaaaaa tcacacccga
     4201 agtggcaaaa gctatgaacg cattaaaaga aaacaatgtt ctccccgtca tcgctacagg
     4261 acgtacagaa gcagaaatcc actctatcat ggaagatgcg ggcattactt ctgcggtcac
     4321 catgaatggt tctttcattc gagtagacgg cgaagaaatc tattctcaaa cattttcttc
     4381 agaagaatgt caaaaaatgt atgatcatgt acagttgaac ggtcatgaac tttcttacta
     4441 taacgatcag aaaatctggt gtaccggtca tagccaaaca atgatcaatg cttacgactt
     4501 cattcattca gatgttccgg aaattgatcc tttaggcttt aaagaaaaca cagtaaatat
     4561 gttgctgatc ttatctcaat caggtgacga atactatcac gaacattttc ctgagctaac
     4621 tttttatcgg aatggtcctt actcgatcga tacagtgaag aaaggaatct caaaaggggc
     4681 aggtgtcaaa cgtctgcaaa aagaacttca gctggaaaaa gttcctactt ttggatttgg
     4741 cgatggtccg aatgattttg ccttgttgga agcttgcgac aacaaaatcg ctatggacaa
     4801 cgcctatgac ggattaaaag aactttctac ctttatcaca aagaaaaata cagaaggcgg
     4861 aattgtccac gcattgaagt attttgatct gatttaagat ctttttttga agctacctct
     4921 tttcttaaga aaatcgctta ttttttctta agaaaggggc agttattata taaataatgg
     4981 gatatgattc gcttttttat tgaatttatc ccaatatatg ctatactaat tttgtatgaa
     5041 aaatacacgt aacccttgtt agctaacggg gacgttacgg attcgacagg cacagtcgag
     5101 cttgaattgc gtttcgtagg ttacgtctac gtaaaaacgt tacagttaaa tataactgct
     5161 aaaaacgaaa acaactctta cgctttagct gcctaaaaac agttagcgta gatcctctcg
     5221 gcatcgccca tgtgctcgag taagggtcct aactttagtg ggatacgttt caactttccg
     5281 tctgtaagtt gaaaaagaga acatcagact agcgatacag aatgcctgtc actcggcaag
     5341 ctgtaaagtg aatccttaaa tgagttgact atgaacgtag atttttaagt ggcgatgtgt
     5401 ttggacgcgg gttcgactcc cgccgtctcc atatatgtat ggttgagaca gataaacatg
     5461 tatgaaaaac gttgttaaat caacgttttt ttattttggt caaggagaga aaagtagaga
     5521 aatacaaaat tttttgcatt gattttgcat tcaaaaaaac attcaaacat ttagaaatcc
     5581 ccaatacgta ttcaggaaaa tctattttaa ggtttacaaa aagaactttt gttcgtacac
     5641 tctttttgag gtgaactttt atgctgatgg aaggaaaaac acaattatgg tttaagcatg
     5701 ttccttcaaa taagtttttt ta
//
LOCUS       DACGMI010000110         4884 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.116, whole genome shotgun sequence.
ACCESSION   DACGMI010000110 DACGMI010000000
VERSION     DACGMI010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.116"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            25..483
                     /locus_tag="IXT46_002839"
     CDS             25..483
                     /locus_tag="IXT46_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAQ4948712.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            592..1275
                     /locus_tag="IXT46_002840"
     CDS             592..1275
                     /locus_tag="IXT46_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAQ4948713.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RSNTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            1422..2036
                     /locus_tag="IXT46_002841"
     CDS             1422..2036
                     /locus_tag="IXT46_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAQ4948714.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETKEAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            2052..2258
                     /locus_tag="IXT46_002842"
     CDS             2052..2258
                     /locus_tag="IXT46_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948715.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            2775..3938
                     /locus_tag="IXT46_002843"
     CDS             2775..3938
                     /locus_tag="IXT46_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAQ4948716.1"
                     /translation="MKKRKKIDWWILGPYLTLSMIGLLEVYSASSYRLLQADENTKSL
                     LLRQLIFIFLSWSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGA
                     QRWISLFGIQFQPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPK
                     IAGALMILSIAWVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNH
                     AYERIATLRDSFIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIF
                     SIITEELGLIGALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVG
                     SIAGLMPMTGVPLPFVSYGGTSYLILSLGIGITLNISSKIQAEELPLYRPEKQ"
     gene            4030..4827
                     /locus_tag="IXT46_002844"
     CDS             4030..4827
                     /locus_tag="IXT46_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAQ4948717.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSVPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVIKAISQQLKDVTSIFKLPKAVGKLLGSIQTNLPESVLLDCGMDFL
                     KDNNKKIDTLSVPVDGSWDFNDNTPSGSVLELDLTKNQEAIKKFLNN"
BASE COUNT         1660 a          784 c          996 g         1444 t
ORIGIN      
        1 ataaaaagca aaggggtgga tgttatgtat cagcaagtag aagaatatgt caaaaagttc
       61 caagaaaaat atcctagtta tcaatcagaa aaattaggtt tcttttcatt tggggataca
      121 gaaaaaatgg cagacgagtt gagcgaacta gttgtaaaaa agataaagac tggtacatca
      181 agtggttacg atctgtataa acaagagaat gagcctttac caaaagttgg tcaattagac
      241 gtggtcctga atggaaaaaa tgaaccagtt tgtatcatca aaaatataaa tgtgaccatc
      301 ttgcctttta gtgaagtcac gaaagagcat gcttggaaag aaggagaagg ggatcggaca
      361 ttagcttatt ggcggaaagt ccatgctgag ttttttaaac atgcttataa agaagcgttg
      421 aacatagaat ttacagaaga gaagctggtc gtatacgaag aatttgaagt aattttcttt
      481 tagtaagaaa ggtctgctga aagaaatagc tcattattga ctcctgaata gaaaagggtt
      541 acatttttat atgaagctgt atttttatat aacattactg gaggagatat tgtggataca
      601 ctggaacaaa tcaaaggcgg agtcgtcgtt tcttgtcaag ctttggaaaa cgagccgcta
      661 cacagttctt ttattatggg gagaatggct ttggctgcaa aagaaggcgg agcagttggt
      721 attcgatcaa atacgacaga agatatcaat gaaatcaagc gaatcgttga tttaccggta
      781 atagggatta tcaaaagaga ttacgatggg tcagaagtgt ttattactgc gacagaaaaa
      841 gaagtggaag aacttttgga gacgcaagca gaaatcattg cactggatgc aacttctcgt
      901 aaacgtccga cagaaaaaac aactgctgaa cttgtccaaa tgattcacga acacggtcgg
      961 ttagctatgg cagatatttc gacttttgag gaagcgcttc aagcgcaaga agatggtttt
     1021 gatcttttgt ctacgacttt agcaggctat acagaatatt cacgaaagac gcagacacct
     1081 gattttgatt tattgaatca aatcatagaa caagtcgata tcccagtaat tatggaagga
     1141 catactgact ctcctgaaca agtagagaaa gcatatgaat taggtgcttt ttcagtcgta
     1201 gttggatcta ttatcacccg tccgcaattg atcactaaaa gatatgtcga agccgcaagt
     1261 aaagcaaata actaaaaaac acgcacggca cagattcttg acaaaaaaga aaaattgata
     1321 gatagtttaa agcagattct aagaagatga aaaaagcatt acttttcatt ttgtcttcaa
     1381 gatctgcttt ttaacgaatt ttatagaaag aaggcgaaac catgtttgaa cggagtcctt
     1441 cagaattgac agaacgtgaa aattacaagt tgctgattgg ttcagtcatc cctagaccag
     1501 tagcagtagt aacgactaaa tcagcaaaag atatagtgaa tatcgcaccc ttcagttact
     1561 tcaatatcgt cagttcgaat cgacccatct tatccttggc gatccagaga aaacaagatg
     1621 cagtaaaaga cacagcaaag aatattcttg agacaaaaga agctgttatc catatccttg
     1681 atgaggacaa cgtagaagaa gtaaataaaa cagcagccaa tctgcctaat gaggaaagcg
     1741 aactgtacct gactgacttg actttaactg attcagtaat catttcagta ccagcattga
     1801 cagaagcaaa agttcgtttt gaaacatcct tatatgaaca tgtcgagata cggaataaaa
     1861 ataaagtaac agctgattta tttttgctag aagtacagaa atatcattta aatgaaacag
     1921 tctatgatga taagacagga aggatcgatc caagaaaatt gaatgctgta agccgtttgg
     1981 caggaaatga ttatgcagca ataggagaaa ttttcacgat tgcacgtccc gaataaaaag
     2041 gagcactagt tatgttaaaa ataagctata aaccatcgac agattcaaaa gaaatgaaaa
     2101 aagaatatga aacagtgaat gattttctgc aagggcagta cttagaagtt ccgccattgc
     2161 aagaccattt tgtcgttact actgttactt tagatggtaa ggaaatagaa atgccagatc
     2221 aaacgattag cggattgttt aattacttta acaaataaat atttattccg aaaagtgaaa
     2281 aaaacatata aaaaaacaca taaaactaaa aaattatcaa agaatcctgg tgcaactgaa
     2341 agaatttgca acgggattct ttcaacttat ttgttatttt tttctaaaaa atattaaaga
     2401 ttgttaaatt tcactatttc atttcaaatt ccattgccta atcattagga aaagtctatc
     2461 atgaactcgt aaatagaata tagtaataac cttgttaggt gaggctccta tacaaacata
     2521 ggctgttgcc cagaaacgtc gaaagtcgcc aatgggtaaa acagaaactg tcggattaag
     2581 gctttttcca atagctaaga atgttttctt tacgttgtat agtgctaaaa ctcggacgat
     2641 gagatgatgc taggtcagaa ttcttgttcg aaaaggtttc tgaccttttc tttatatttt
     2701 tgtgactgac ttatttgatg agacaaactc gctcctcacc tgacaagtgg attgctgtgt
     2761 gaggaggaga tgcggtgaaa aaaagaaaaa agatcgattg gtggattttg ggtccttatt
     2821 tgactttgtc catgatcggt cttttagaag tatacagtgc cagttcttat cgtttattgc
     2881 aagccgatga aaatacaaaa agtctattat tgcgtcaact aattttcata tttttgagtt
     2941 ggagcgtgat cttcttagct cgttcagtca aactacacta tttacttcac cctaaaatag
     3001 caggatacgg tttagcctta tcgattttct ttttagtatt agtaagaata gggatattcg
     3061 gtgtcactgt caacggcgca caacgttgga tctctctgtt tggcattcaa ttccagcctt
     3121 ctgaactggc aaatcttttt ttgatttttt atttaagctg gttttttcgt gacggaaata
     3181 gtagcccaaa agatctaaaa aaaccattcc tgattacagt aggtataact tttctgattt
     3241 tatttcagcc aaagattgct ggagcattga tgatcctttc gattgcgtgg gtcatatttt
     3301 gggcagcggc ggttccattt aaaaaaggga tctatctaat cgttactttt tctgcattgc
     3361 tgattggagc agcaggcggg gtattatatt taggaaataa aggttggctt ccacagatgt
     3421 ttaatcatgc ttatgaaagg atcgcgactt taagagattc ttttatcgat agtcatggtg
     3481 cgggctatca aatgacccat tcgttttatg cactatataa tggtggcata tttgggcggg
     3541 gattaggaaa tagtatcaca aaaaaagggt atcttccaga gacagaaaca gattttattt
     3601 tttcgattat tacagaagag cttgggctaa tcggtgcatt gtgtgtgctt ttcttattgt
     3661 tctcattatg catgagaatc ttttgtttaa gcagtcgctg taaaaatcag caagctggat
     3721 tgtttctttt aggattcgga actttgctat tcgttcagac gataatgaac gtgggaagta
     3781 tcgcggggct gatgccaatg actggtgtgc cattgccatt tgttagctac ggaggaacaa
     3841 gttatctgat cctttcttta ggaatcggaa tcacgttgaa tatttcttca aagatacagg
     3901 ccgaagagtt gccgctctat cgacctgaaa aacaataaag agaaactgag aaactctcag
     3961 tttgaattat cataaagtac aatcttttat ttttcaagcg agaggttctt ttagaaagag
     4021 gaattcgcaa tgaaagtatc tcaaaaaatc atattatcta ttttgttact gcttacatta
     4081 gtagttggct atttttcgat tgagtttatc catggatttt cgtctgcaaa acagagttca
     4141 actgtgaaaa aggtagagcc gaaaagtgtc cctaccacac taaatgtggc tttgattggt
     4201 tcagatgctc gttcgaaaga cgaaaacggt cgctcggatt cacttctggt tgcacaatac
     4261 aaccagaaaa cacaacaagc aaaactgatc tctatcatga gagattcata tgtcgatatt
     4321 ccaggttacg gaatgaataa gataaatgca gcttactctt atgggggagt tgatttatta
     4381 aatcaaacat taaaggaaaa tttcaaattt gaagctccct attatgcaag tatcacattt
     4441 caagatttta tcgattgcgt taatgaactg tttcctggtg gagtcaagat cgatgcagaa
     4501 aaatctctag atttagatgg cgtatatata aacaaaggag agcaagtgat caaagctatc
     4561 tctcagcagc tgaaagacgt aacttcaata ttcaagctac ccaaagcggt tgggaaatta
     4621 cttggtagta tccaaacgaa ccttccagaa agtgtgcttc tggattgtgg tatggatttc
     4681 ctcaaagaca ataataaaaa gatcgataca ttatccgtac cagtagacgg cagttgggac
     4741 ttcaacgaca atacgccttc cggaagtgtt ctggaattag atttgaccaa aaaccaagaa
     4801 gcaatcaaaa aatttctgaa taattaagta aagaaaataa aagaagttag aaataacaat
     4861 ctatgttatg ttctgacttc tttt
//
LOCUS       DACGMI010000111         4882 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.117, whole genome shotgun sequence.
ACCESSION   DACGMI010000111 DACGMI010000000
VERSION     DACGMI010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.117"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(84..1181)
                     /locus_tag="IXT46_002845"
                     /pseudo
     CDS             complement(84..1181)
                     /locus_tag="IXT46_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180804.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            complement(1311..2687)
                     /locus_tag="IXT46_002846"
     CDS             complement(1311..2687)
                     /locus_tag="IXT46_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4948718.1"
                     /translation="MIKNAFAYVTRKSLRSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2687..3343)
                     /locus_tag="IXT46_002847"
     CDS             complement(2687..3343)
                     /locus_tag="IXT46_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4948719.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(3353..4630)
                     /locus_tag="IXT46_002848"
     CDS             complement(3353..4630)
                     /locus_tag="IXT46_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4948720.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(4649..4804)
                     /locus_tag="IXT46_002849"
                     /pseudo
     CDS             complement(4649..4804)
                     /locus_tag="IXT46_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
BASE COUNT         1538 a          886 c          594 g         1864 t
ORIGIN      
        1 ctccttgcat tcgttttcat aaatctatta taaaagaaaa gactgtagac atcatccata
       61 aaatggactt tgtctacagt ctgcgcattc tcattagaga acactccctt ttttgtgact
      121 tttctgaagc tagagtgaat actttcaact gcattagtag tgtacatgat ttttctaatg
      181 gcgctgccat aatcaaagag ttgttcaaca tgagaaaagt ttcgtttgca tacatctact
      241 gcaccagaat aatgagacca ccgattttga aaactgtcga aggcagcgtg tgcagcgttt
      301 aaagaagaag cactgtagaa ttttttcatg tctcgacaga cttccttata atccttactt
      361 gggaggtatc gtaacgcatt tcgaacaaga tgaacaatac agcgctgcac aatgacagaa
      421 ggaaaaattg cttttgcgcc ttctttgaga ccggaaacac cgtccatcga aatgaaaaaa
      481 acatcttcta caccacgtac tttcagttca tcaaatactt gcatccagcg atttttagat
      541 tctgtttgat tgagccatag gcctaaaatc tccttgtttc ctttaagatc atagccaaga
      601 atggtgtaca cagcatattc tttagcttca tagttttcgc gtaaagtgac gtacatacaa
      661 tcaacgaata gaaatgcata acacttggct aatggccgag cttgccattc ttccaattca
      721 ggaaggacgg catccgtgat atcagaaatc atttcgtggg aaatatcaaa gccgtaaata
      781 tcttcaacgg ttgcggcgat atcgcattga ctcattcctc gtgcatacat ggaaagaacc
      841 ttaccttcga tgtcggagac atctcgtttt ctattaggaa tcaactcagg ttcaaaagaa
      901 gcctcccggt ctctgggaac atcaatgttt actttaccaa agctcgtttt aagcgtctta
      961 ttgccataac cgtttcgtcg attgtcatgt ttctttggct ctttagaatg ggcgtcatac
     1021 cctaaatggt tattcaattc tccttgaagc attttttcaa ataagggacc aaacacatct
     1081 tttaaaacat cttgcatatc ctctacagat tcgggttgat aagtattcaa aatggattca
     1141 gctaacttct cagcatcagg atttcttttc tttctagcca tcgtgtaatc acctcttgat
     1201 cttattttag aaaaataaaa accgtgaagc aaccacccgc ctaggattga tggttactta
     1261 cacggtttat attacactct catttttggt gctaaaaagc accgaaaatt ttaattattg
     1321 tcaattaata attcttttgg attccttctt aatatattga atgaagaaat aatcaatgat
     1381 acaagaagta ctaaactcat aaatataact acataaatca tgaatttagg taatacattg
     1441 atatctaaac ttgataatgt cttgttaaat ccttcagctt ctgccccacc acctaattgg
     1501 ctagatgcag attgtttagc tatttgttta gctatatcac cagtaacctt attcaatata
     1561 ttattcccaa gcttgtcagc tgtatattga gctaagaaat aggaaccaac gaatgcgggg
     1621 attgatataa ataccatctc aattaggaat tgaccaaaaa tttctaattt tgatatacct
     1681 aatgatagta atactgctat ttctttcttt ctagcattca tccataagaa taataataat
     1741 gaaactacaa ctcctgcaaa tattaatgag ccaaaaaata atttatttga aattgagtaa
     1801 atacctgata tagattgttg taatgcaggg taatttgatg aacttttaat caaattatat
     1861 tctctccaat ttatatctaa tttcccaaga tcttttatta cactatcaag attcttatca
     1921 ccttttacaa agaatgttgc atcttggtat acagctgtat cttcggtatt accataaact
     1981 ttagcagctg tatgaatatc agtgattaat gtattttcgt atagttcttg tgctgcactt
     2041 actccaccgc tattatgccc atcgaataga cctttaattt ctacttctac tgtttcatct
     2101 gcacctttct cattatcagc atcaaataaa ttagatttta tttttatctt atctccaact
     2161 ttaaggttat ttttttcagc taaatcttta tgcattaaga ttttattttt atcttcattt
     2221 tctaaatgct ttccttctac taatttatat gcttctgata caaattttgt ttcttttgtt
     2281 gagtcgttaa ccccagttaa cataactgtt cttttaaaat tctttgctct ttcaggtgat
     2341 tgattcgcaa gagtctcttg agtttcaata atatcataat caactaaatc tgcaacactg
     2401 tttattcttt ttacatagga gtctatacta tctgtttgag atatcttttt aatatcttca
     2461 ccttttacat ttcccccacc tctaggtgtt cctggattta cttgtctatt tatctccata
     2521 gaaaaactat ttgttatatt agcaaatgtt tcttttgaag ctctgtccgt agcatcttta
     2581 atagataaac taatgagact taaagttgac atagataaaa taactaatat gataattaat
     2641 gatcttaaac tttttctagt tacataagca aatgcatttt ttatcattat tcaacctcca
     2701 aattcatttt atttactttt ttcaactttt taccacttag ttctaaaatg atatccgcag
     2761 aatctgctac ttccttacta tgtgttacaa ctattacaca tttatttcta tctttagcta
     2821 atgtctttaa tatattaatt atttctccag cagtaacact gtctagatta ccagtaggct
     2881 catcagctag tattattgga gcatctgata ccaatgctct agcaatagct actctttgtt
     2941 gctgtccacc agataatttc ataacatttc tttttatttg ttttttatct aaacctagtt
     3001 caaacaagat actttcatct gctgatttat ttactaatct aatattttca attggtgata
     3061 aataatctat taaattatag ttttgaaata ctaaagatat attatttttt ctatgattac
     3121 tatatccttt attttgtata tcttcattct taaacaatat ttttcctgtt tgaggtttat
     3181 caagtccagc aagtaaggaa agaagtgtag attttcctgt tcctgacttt cctactatcg
     3241 cataaaactt cccaagttca aatttttgat ttactcctga caaaactttt tctttagaat
     3301 ttgcataact atatgctaca ttctttattt ctaatatatc cattattttc tcctaactta
     3361 tttttgataa gatttcttta ggcttcttga ttaacattaa tgaagaagca aatacaactg
     3421 ataaaacaat aatacttatt aatattaaat aactttgtcc aagtgttgtt atatttgaca
     3481 taaaactact attatttatt aaacttccac cggaaatcat tgaatcctct gagttaatga
     3541 atccatctac aattactttt agtaatacat ttcctaaaaa taaggaagat attatacttg
     3601 gtatcgatat gaatattaac tcgaatataa attgcattat aatttgtatc ttagatgttc
     3661 caatagataa gaatatacct atttcataaa ttctttccct taaccataga atcaagatta
     3721 atgaaagaac aaccatccca cctaacataa tagaataagt cattactttt attatatatt
     3781 ttattccact cactgactct aaagactctt caaacgcatt agaatctttt tcaacaaaat
     3841 actttgactc atcaatttta agctctttca atttgtttaa ggctaagtct gtagattctg
     3901 cactaccaga atacattaaa attttatttg caatttcatt attttctgaa ttatttaata
     3961 tctcttggct tgttgaataa tctacaaaca ccatattttc actaaaatca gaagataatc
     4021 ctgtatatgt ttcctgtttt ttaccagaaa agatccctat aattttaaat ttatgacttt
     4081 ttatttttcc acttttttca atatctagta attcaagatc aacttcatca cctaatttta
     4141 gattgttttg tttagcaaat tcttcatgaa caataattga attcttatca ttttcttcta
     4201 tatttttacc ttctttaatt gtaaatactc cactactaaa taaaatattt cttttagtat
     4261 tatttgtagc ttcgagtgaa acaacattct taaattcgtc agataaatct tctctattta
     4321 ttctttgttc tccgctaact actttagcat cttttagttt tgctaatcca tcatattgaa
     4381 ttattttttc ttcaatttct tttaattttt caatatcttt aaattgatta acattaaaat
     4441 atttaccatc tttttttgtt attgatattg aagaattaga actttcatat aaagcctttt
     4501 ctatttcatt gcttgatttc attattgtta aacaagaata caagcaagaa agaactatag
     4561 ttaatatgat aaaaattatt aaagttctat ttttctttct tgtaatatat gctatagcat
     4621 tttttatcac tttcctaact actcctctct attttcttac tccataacta attgcatcca
     4681 ctggacaagc atttttacat cgtccacatc tgatacactc cagatgattg caattctcaa
     4741 ctgaatcttt attcatttgg caaacttttt tacattttcc acaattaata cacttatcct
     4801 tatcctgaat cggctacact agactagaca gaaaaaataa ggtgtgtaga ataataaaaa
     4861 acacactgga ggatttttca tg
//
LOCUS       DACGMI010000112         4813 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.118, whole genome shotgun sequence.
ACCESSION   DACGMI010000112 DACGMI010000000
VERSION     DACGMI010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.118"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(57..1205)
                     /gene="nagA"
                     /locus_tag="IXT46_002850"
     CDS             complement(57..1205)
                     /gene="nagA"
                     /locus_tag="IXT46_002850"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAQ4948721.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1281..2117)
                     /locus_tag="IXT46_002851"
     CDS             complement(1281..2117)
                     /locus_tag="IXT46_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4948722.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2301..3518)
                     /locus_tag="IXT46_002852"
     CDS             complement(2301..3518)
                     /locus_tag="IXT46_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4948723.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3901..3984
                     /locus_tag="IXT46_002853"
     tRNA            3901..3984
                     /locus_tag="IXT46_002853"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3935..3937,aa:Leu,seq:gag)
     gene            complement(4224..>4813)
                     /locus_tag="IXT46_002854"
     CDS             complement(4224..>4813)
                     /locus_tag="IXT46_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948724.1"
                     /translation="FLDMNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYF
                     GNTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLI
                     VGIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMA
                     VKELMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         1467 a         1001 c          775 g         1570 t
ORIGIN      
        1 aaaaaacctt aaaaccaaac ttaagaagtt tagttttaag gttaacttaa attatattat
       61 gcgtggaaac gttccacgcc atctagataa gttgcttcca atgtcatatc agggttcaat
      121 acgataaagt ctgcatcgcg tccttgagcg atttttccac atgtatcatc gattttacag
      181 ctgattgctg gaatcagact agccatcatg actgcttgtt ctggtgttgc taatccccag
      241 tctacaacat ttttaattgc ttctttcaat ttcaatatac ttccagctaa gttgccagat
      301 tctagacgtg ctgttccttc ttttactact actggaaatt cgcctaaatt gtaatttcca
      361 tcaggcatcc caccggccat catacagtct gtaattaatg cgacatgatc atgtcctgct
      421 ttttccatta ggattcccgc agcatttgga tgtacatgat ggccatcaca aatcaattca
      481 gaaaagacat gttctaaaga taataacgca cccaccatac ctggttcgcg atgattcaat
      541 ccacgcatac cattgaaagc atggacaaat acacttgcgc ctgcttcaac agctttttgc
      601 gcttcttcta gtgtagcatt actgtgtcct agagaaacaa ctactccttc ttcagtcact
      661 tgtttgacaa actcttctac accttgacgt tccggtgcta aagcaatttt tttgattaaa
      721 ccacctgaag cttcttgcca ttcatggaaa gtatccaaat caggatcccc gaaataactt
      781 gggttttgtg cccctttgtg ttcttctgtg aagaaaggac cttcaaaata gattcctttg
      841 attttagctc ctggtgcttc ctgatacatt ttgccgattg tctcagctac atcttttaaa
      901 cgttctttgc ttgacgtcaa tgttgttggt aaaaatgaag tcactccaca agataacaga
      961 ccttcagaca tcactttgat gccttctgca tcattatcca ttacatcatg attcatatag
     1021 ccgtgaatat gtgtatctac caaaccagga gcaatccatt tgccgctttg gtcaatgatg
     1081 ttgacttctc cctcaggtag ttctttggtg tattcaccaa aaagtccatc ggtaatttca
     1141 agatagcctg catgtttgac acctgacgct aaaaagaatt tgtcagcata gataaaagtt
     1201 ctcattctat tctctccctt tgtttttcta cctctaaagt actcttattt agagaagaag
     1261 tcaagaatgg tctacaccat ttacaaattt tttgaaattt gtttcacagc ttgtgctaag
     1321 ccttcataga atgctgctct ttctggttct tctttacgct tgtatattaa gcttttaagc
     1381 acaaataaat cattgaggta atagtagcta ttcttctctt gagcccaata gattccttga
     1441 ttcacctgtt ctaacgcttc gtcgatttca ttttgatgga ataagaaatt tccataatta
     1501 taaaaaattt gcgaaaattc actttttgat cgttcatcag ctgattgatg cagcagttgg
     1561 atgcttcgac tcaaatagta gcgtgcttca gccgtttttc ctgccacacc atatattttt
     1621 ccgatacaac taatcagttg tatttctgtg tcagaaacat ggattctttc tttttggcta
     1681 gagtagctta atgcttcttt caaataataa agggactgag agatattttg acgcaacgtg
     1741 aattcgcaaa caccgagata ataataatag cgttgaaagt cagttgcttg atacagattt
     1801 tcagaaatat cagaagattt tagtacttgt tctaacttcc gataatcacg tttttggaaa
     1861 caactatcca acagttcaaa taatttatcg tttgtccgag tagtttttcg agagagattc
     1921 atcacatgat caatcgttac ccctagccgt tgacaaatct gcatcatcac caatacattc
     1981 ggcagttcct cattattttc gatccgactt aatacacttt gtgaacaaat atcatgcgaa
     2041 agcatttttt gcgtcatttt ttgttctttt cgaatctctt taatgatcgt tccaaaggac
     2101 tcgattaacg tttccataag tatcctcccc aaaatatgcg tattcgcatt ctattcgtat
     2161 tttactttag gaagtcgcaa acttcaagaa aagacttgca actaaataat atactttagt
     2221 tatttaagaa aactccacta gaaagagagc ctcagtgtgt ttgtctgtgg ccctcctact
     2281 gaaaaatttg gtttttaaaa tcatttttgg cgataggttg ctaggaattc tctcattttc
     2341 ttagctgttt gtttcaaatc atccatttta ggaagataaa cgattcgaaa atgatctggc
     2401 tggttccaat taaatccacc accatgtaca agtagaatat gatgttcatg taaaaagtcc
     2461 aaaacgaatt tttcatcatc caaaatattg aatcgctttg tatcaatttt tgggaatata
     2521 taaaaagcag cttttggttt tacggctgaa agaccaggaa tatcattgat tgcattatag
     2581 atatattctc tttgttcata gatccttccg cctggcagga gcagctcatc gacactttga
     2641 taaccgccta gcgcggtttg gataatttgc tgagacaata cattggaaca caaacgcatg
     2701 gaggacaaca tattcagccc ttctatatag cctttgacgt gtgacttatc tccacttagg
     2761 accatccagc ctactcgaaa tcctgctaca cgatgagatt tggatagacc gttcagcgta
     2821 acaacgaaca aatcaggcgc taatgtagca atcggaatat gttctagacc atccatcact
     2881 aagcgatcat agatttcgtc ggaataaata atcaggttat tttgtcgagc tacttcaacg
     2941 atttcttcta ataattcttt tggataaagt gccccagtag gattattagg attaatgata
     3001 acaatagctt ttgtccgact cgttattttt gatttgatat catcaatatc aggataccat
     3061 tctgcctctt catcgcaaat ataatgaaca ggtgtgcctc cagctaatgc aatagaagcc
     3121 gtccacaacg gatagtccgg cattggaacc agtacttcat ctccattgtc cagcaacccc
     3181 tgcatacaca tcgtgatcaa ttcgctcact ccgttgccgg tgtagatatc attgatcgtc
     3241 acattcggaa aatgtttcag ttggcaatat tgctcaattg cttttctagc agaaaagatc
     3301 cccttggaat ctgagtagcc ttctgagtca cgggcattca tgatcaaatc acgaatgact
     3361 tcgtttggtg cttcaaatcc aaaaggtgcg ggatttcccg tgttcaattt taaaatacta
     3421 atgccctctt cttgcatccg ctccgcttct tctagaacgg gaccgcgaac atcgtaactg
     3481 acaccttcta atttgttgga tttttcaaat tctctcatca cttagccaat ccctcatttc
     3541 aaaaagttag aactttccaa attttttgtt atttactatt tcaatatcat actccatcct
     3601 agaaaatttt gccacttatt taggaaaaac gtaagtatta aaaaaacaca aacaagcgtt
     3661 gagaacttaa ttgtcatgat agtcattcca tagattcgct gcccaatcca ttgcaattcc
     3721 acaaatgatt cctagcataa aaccaagcaa aaaacgtccg aatgcaagtc caatcaatac
     3781 acctaagatc attcccagtc ctgaaaattc tccgtcatat ttctccatct taataagtcc
     3841 tcccattttt gagcttgaca actatgtaaa acctcgctat cattagtgtg ttattattac
     3901 gcagatgtgt tggaattggc agacaagcat gattgagggt catgtgagcg ttagctcgtg
     3961 tgggttcgag tcccatcatc tgcactacaa ctcgtgaagt taattttgct tcacgagttt
     4021 ttttgtttga acgtttcttt atgccattat atacatatca ctgtatcctt tacaaaaaga
     4081 acgtacaatc atgtaaacag cctgaggtga gtatatgaag gtcggaaaca agctactcgt
     4141 agaaacttgc aagtgttaaa acaattaatc gaaaaacgag taaaatccct cacctaatac
     4201 taaagcgagg gattttttgt atattatctg tttatcaccg ttattataaa ggtacaaata
     4261 ccaagcacgg ttaatccaaa ttgcataaat tcattttttt gtacactcat gcttttcatt
     4321 agctctttaa ctgccattag tactaagatg gcgataacaa cataaagtat atagtacgtc
     4381 cgcattccgg aagcccatac tgtgggagaa aatcccataa ttaaccttga acaaaatccc
     4441 attatcatca aaataactaa aaaaatagaa gttttcttat tgtcaaaact taaataaatt
     4501 ccaacaatta aacatagtaa taatgccaag actactaaag tagctatcca agtacctgga
     4561 taaaaaagtg acagtttcgt tcctaactct gtaaagagat tattcaggtt actactactc
     4621 caaatcattg cccttttatt tccattgacg taagtaaagc tttgacccat tgtattacca
     4681 aaataaataa tcaggtttaa gaaaaacggt aatgcagtca atatacgcac ataatagttt
     4741 tgacatttcc tatatgttag aaggaaaatt aagaaaaata gcaataaaaa taagatattc
     4801 atgtctaaaa aaa
//
LOCUS       DACGMI010000113         4809 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.119, whole genome shotgun sequence.
ACCESSION   DACGMI010000113 DACGMI010000000
VERSION     DACGMI010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.119"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(91..1176)
                     /gene="xerS"
                     /locus_tag="IXT46_002855"
     CDS             complement(91..1176)
                     /gene="xerS"
                     /locus_tag="IXT46_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAQ4948725.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3252..3770)
                     /locus_tag="IXT46_002856"
     CDS             complement(3252..3770)
                     /locus_tag="IXT46_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HAQ4948726.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1580 a          786 c          729 g         1714 t
ORIGIN      
        1 tataaaaatg ataatgaagc ttgcctttaa agttgggctt ttatctaatt ttagagacag
       61 gcttcattat tatactattt tttactacat ttacaaagcg ttcaaagcat caattgtagc
      121 tgcattgtct atatgagtat ataaagttgt tgtatttgta cttgtatgtc ccaattgttg
      181 ggcagttaat accaatgaat ttgtctgttg atagagtcta gtagccaaag tatgacgtaa
      241 tttatgtgga ctgacttgga ctctgaatcc ttttgaatat tttgctacca tccgttcgat
      301 tgcaataccg gatatacgct tggcttctcc ttgataaatt gctagaaata aagctttttc
      361 gttttctgtt actttgtatc gttctttccg aatagctaga taattagcta aatattccat
      421 tgcaaatgct gctatattta ctgcgtctct cttatttcct tttctagtta ctaccacatt
      481 attcttttct aaagataggt cctctaaatt aatatttaca acctcggaga gtcttaatcc
      541 agatcctaaa atcaatgcat tgatcgccag gtctctttct acatctcgtt gataatagat
      601 caaagctcgt ttgctcaaag tttttttata ttcattggca atataatcta gataattttg
      661 tgtatcttcg tctagaaata attttttctc gattgcgttt gcacgggcag ctaacgtagt
      721 tttatctgtg atagttgcta cttgatccat aggattattt tctaagtatg gttttcctaa
      781 aggattattg gaacttttcg aaagatattt aaatagaacc tttaatgctg tgatatttct
      841 attgatagta gaagtagata gacctaagtt attattatct ttgagcttag tttttgttgt
      901 ctcttttttt acattttcct ttgtgcgacg tttcaaatga gatttgtaca agtttagatc
      961 ataggcagtt aactgtctta tcgaggtgat tgaagtatcg ggaacgatag actcactcag
     1021 aagccattca taaaagagct tataattttt tagatattct aaagtagttc gaggtgattg
     1081 atctttatcc tcacgatctt gaacaaaatc ttttatataa tcgggcatat gaagtatgat
     1141 tgtatctatt ttttgatata tttctgtatt tttcatgtta ttcatccttt cgataagtag
     1201 gggagaggag tatctctata attggactat accaattata gagtgttttg tcaattggta
     1261 tactctgaaa tttattaatt tatttcaaaa aagcagataa ataggtatag atttaataat
     1321 ttaaaataaa tggtatacat gaataggaaa ggaaacagaa ggaggcaatc ttaatttttt
     1381 aaattgtcta aattatatag aaagaacaat ctttctatat aattagacat aagagagact
     1441 acggttgatt tgatattaac aagcgtatat gaatgtatat acaaataaaa aaggggaggg
     1501 agaagttaaa gaaaattcag agaagtgggg cactcagtag tattaacaat ttaaaaggaa
     1561 tttcttaaag aaaatgggtt gcatcctgga gatacaattt ttttagataa agaaaaaatt
     1621 caagcaacaa ttcaaaaaaa tcttaactgc tgagattgat gtagcaatat ctcaatcatc
     1681 aacaaagtac gatcctgcct ttcaaaagct tattgataaa tgtttattca ttataaaaat
     1741 aaaagaaaaa tttatgtcag cttttttcat caaagtggta atgataattc gtctattaat
     1801 tgtatttttt aggaaatatg gtataattgt tttaacgaaa aggtaattca tgatacacca
     1861 aaaaccacta gctggcgggc tagtggtttt cttttacgtt ctattcagat taacgggtag
     1921 gcttactgtc ttttttggca ataattttgc aatcaagcca tttacagatg taatgcgcgg
     1981 atacttctgc taagattgca aaaaacatat cgaaaaggta attcataata caacctcctc
     2041 cccttgccat aataggccgg ggtagcagac agcataaata ttataccata actgaaaatt
     2101 tcattttagt acatttcaat atattgatga accagcacaa taaaacatgc catgactaac
     2161 agaaaaaaac ttattaaacc agatataact tgtaaacatc caactatata gaaaacgtaa
     2221 attttctata tagttggatt aagataacga ctatttattt tatcatattt ttactatacc
     2281 ctatactttt acttggtata tttatgaata atcgcaaatt tacccctata ctactagttt
     2341 gtaagttaga ttaataaaaa tactaaagtt atttgttctt ttattaaata cacctacaac
     2401 ttataaattg atggtattta gataacacga aagaataaaa ataacagctg atagtaaagt
     2461 ttgttgacga ttgctactca atcgaaagtg agttagtgcg tatgaacttg cttctgaaaa
     2521 cttatgaaat gaaagacctt ttacatcttg cagaaatcgt tactgggatt aaactaagca
     2581 ataaaaacta atgttcccct cattctttga acttctacta tttgatttat ttattctgat
     2641 aaatgacgat ttcaccttca ggatcttcaa atcccgtata gaatttattt aagatctctt
     2701 cagtatcagt aataggatag gcgataggcc acataccctt tgatggttag aataaactgc
     2761 tcaaaatctg tatcgtatgt tggctttagc atattaacaa aggctatctc caaattataa
     2821 accataagcg ttgaatcgtt cttaacaatt tcaattcttc ctaacccaaa gtcagaagat
     2881 ataattaccg gacttgcctt acccttcatg tgggttgttg agattccata tttaaaggga
     2941 attgtcggta ctatcggcgg tctgaaaaac atcccaaaaa taaaaaaatc tttcccctgc
     3001 tagtctccta agtccctttg tagcggatat ggcaccataa tctcatttta tcgaagtgag
     3061 tcatggttta tctgttggcc aaccaaaatt gatacaatct aacgatgcac cctctacggc
     3121 attctagggg agtgcacttg cattcaccca ataaaaaccg gcagttagca aagaacttat
     3181 gtagtcgtat gttcttactg ttaacataca agaggtctcc tttccacaat tgcttagcag
     3241 taaacgggaa tttacaaagc taatctcttc cattttctta tctttgttct aaaagtccca
     3301 aatggagcaa ctgtatttac atgaataaat ttatatactt cccatacagc cgttttggtt
     3361 gcctcgtctg cccattttct tttgtgtgca gtgaatagat cttcatcact cattgaatca
     3421 atcatcatgt taatatcatc aatattacga ttgagaattt cctctaattc tttcaatggt
     3481 agatgtgcat aggtatttgt aaaccactta tataactctc ctaactgatt ccatttaaat
     3541 tgatcagaag gcgttttaac agataatcca tttctttcat cattttccca ttttagaatt
     3601 aaattcgtcc aaccaacttg atatgctaaa ttttcagcag gtgttctatc cacttcctca
     3661 actcttttat ccttcaattc ttcaggaata gtttcaaatt ctaaaatata tttagtataa
     3721 gtcctattta tttctttttt taattcttct ttatttttat atgttctcat tatattacct
     3781 ccataaattc ctaattgtct cctttaattc atctataatt tcatccacga tattttaatc
     3841 cgttctacaa tgcatatctg atatgcattg actgtctaac tcatatgtga atgatttata
     3901 aaatatccca acgtctcatc taaagaaatg ttgatcgtca gcaaggagct aaaaaatacg
     3961 aatatatttc ttttgtagta aaatcggact ggtttgcata tcattttctt cgtaaatatc
     4021 aaaatcatgt taactactat caattactaa taaaaactac cactttaagc gttaagaact
     4081 gttaagttta gttaagtgag gatagttcac aaaatccatt gttaaacttc acgaaagtgg
     4141 taaaactcaa aatgctttat ataggattac agcatcgctc tttcttcgat tgcgcgttgg
     4201 gtaaaaaata ttatgaagta aaaattgacg atgacacgtt ccttacggct catcagatga
     4261 aacagctaca aaaacgaaat gatcaactcg aagaaaattt aattctaaaa aagcgattgc
     4321 catattcacg cctcgctcga cgaactatta aaggtcaaga tttacctgaa gatcatcctt
     4381 tttaggaaat tgaagctttt tatgttgcac aatgcattta taatactaca atgatgtttt
     4441 caccagatat tcttctaggg tgcggtgtaa tgaaacagat acacttgcaa aagaaaattc
     4501 accgcgaatt tactaaaatt atgaataatt atgttaatct tccgaaattt ttttccaaaa
     4561 ttaagggatc aagctggtgt tatagattgt ttaaggttgg caaaaaaata acttcttttt
     4621 aaacaattat agaaaaccga tactctgtta agttggttga cacggtgtcg atttttatga
     4681 ctttcttatt ctgaaacttc actaacggac agtacctaaa aagtctatag tatggacgtt
     4741 tacgagtact attttatcaa aaatgctgct catttcaact tatatgtttt agtgaactac
     4801 ccccactta
//
LOCUS       DACGMI010000114         4742 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.120, whole genome shotgun sequence.
ACCESSION   DACGMI010000114 DACGMI010000000
VERSION     DACGMI010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.120"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            23..694
                     /locus_tag="IXT46_002857"
     CDS             23..694
                     /locus_tag="IXT46_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4948727.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            753..1193
                     /locus_tag="IXT46_002858"
     CDS             753..1193
                     /locus_tag="IXT46_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948728.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1205..1873
                     /locus_tag="IXT46_002859"
     CDS             1205..1873
                     /locus_tag="IXT46_002859"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAQ4948729.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1937..2560
                     /locus_tag="IXT46_002860"
     CDS             1937..2560
                     /locus_tag="IXT46_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAQ4948730.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2616..3002
                     /locus_tag="IXT46_002861"
     CDS             2616..3002
                     /locus_tag="IXT46_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAQ4948731.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3215..4606
                     /locus_tag="IXT46_002862"
     CDS             3215..4606
                     /locus_tag="IXT46_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAQ4948732.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1578 a          782 c         1011 g         1371 t
ORIGIN      
        1 tgatgaaaaa agggggagaa aaatgaattt tttagttgtt ttaaaagata ctctgattga
       61 gcgatctaca tttctatatg ttcaattgca ggaaaataaa acattgctgc atttttcacc
      121 agagttccat ctagaggggc taacattagg agaaatctat caagcagaag ggctgtcggc
      181 tgttttgcac ttttttaagg tagaattgga attaccagta aaagattata tcgagctttc
      241 tcttgaatct tgggatcgag cagtggttga actgtttcca gaaggtttaa tgatcgatac
      301 aaacgatggg aagatccatc tgactgcagc agaactgcaa aaacaaatgc gttatcaaat
      361 agatgacgaa aattcttttt ctatttttag acgtcagcaa aagattctaa aaagcttttt
      421 aaaagtgatc agtaaaaaac ggaatctgat caaaacgaca cagctgttga aaaaatatcc
      481 aggtctgctt cacacgtcta ttcaatttcc tcaattgatt acgatgatcc atcgttttat
      541 acgtatgcaa cagctaccat ctaagaagct gtttcttcca ttgacggaca catttcgagt
      601 agtcaacaga gaagataaaa agaaagtgat tgtgattgac tttaccagaa atcggaatgt
      661 ccttcaccaa gttgcaatgg aaaaggccaa ttaaggcttt ttctttttgg atttttttgt
      721 cataataaat attagatgat ggaggagata atatgatgca aacatggtta gaaaggctaa
      781 tacgatttca gcagaactat cacaaactta tgcagggaag atatgcgaaa tttgatcagt
      841 tgaatcgcgg tctattgatc gctgcgcttg tctttagttt gctaagtcgt tggttgccct
      901 atagaatcgg acaattgttg ttcatcgtct ttttcggatg gatgatattt cgtttcctat
      961 caaaaaaaat ctaccccaga ctaaatgaga atcaacgtta tttgaaatat cttgatagag
     1021 tcaaagaaaa atatcatcag ataaaaaaca aaaagcaagt caaaatggat cgaaaaagtt
     1081 atactttttt tgagtgcccg aattgtcatc aaaagcagcg tgcacctaaa ggaaaaggac
     1141 gaatacgtgt gacatgcaaa acatgtggta taaaattcga aacgaatgtt taagggagaa
     1201 aagaatgaaa ttagtattat tacgtcatgg cgaaagcgaa gcaaattttg aaaattactg
     1261 gacaggatgg ctagatgtcg ccttaacaga aaaaggaaaa gaacaagcag cagttgccgg
     1321 tcaaaaaatg cttgaagccg gacttcaatt cgatgccgtt tatacctctg ttttgaaacg
     1381 tgcgattctt accggacaag tcgcactaga agaaatgggt cagttatggc ttcctataat
     1441 aaaaacatgg cgtctaaatg aacggcatta tggggatctt gtgggtaaaa acaaagataa
     1501 gatgaaagaa atatacggaa aagatcaagt aaaaacatgg cgcagaggat atacggaagt
     1561 tccgccgtta accgcagaaa atagatttga ccgcagatat gatcacttgg atccgcattt
     1621 gatcccatac ggagaaagtc tggaaatgac agtgaatcgg atcattccct tatggcaaga
     1681 tcatctagca ccaaaactaa aagatcggca agatttacta gttgtgggtc atggtaatag
     1741 catccgagca ctgacaaaat atttagaaga tgttcctgaa gatcaaatgg atacgatcga
     1801 tatcccaaat gcacaaccaa tccagtatac attagcagat gatttgacaa ttctggacaa
     1861 aaaaatactt taaagaacac ctttatctaa aagtgagaga tagaaaaaag aagcaaagga
     1921 atggaacaaa aggaacatga aaaattatat atgggacttt gatggtacat tgtttgatac
     1981 gtatcccgca atggtagatg gtgcatggca agcactaaaa gattttggta tcagtatgga
     2041 caaaaaagaa atctacttca aaatgaaaaa gtattctact agttatttga tcaatgaatc
     2101 aaacttgaat gccagagagt ttaatgaatt atttcaccga tatgaaaaag aaagtacgga
     2161 agtttcccgt ccatttccag aaacgaaaca agtactggaa atgctaaaag acaacggcgg
     2221 tcgtcatttc atcctgaccc accgtttgac agaatcaaca tggggcctgt taaaagaaca
     2281 tcgattggca catctgattg aggaagtagt agggatcgat caggactttc ctcgtaaacc
     2341 tgatccagca tctttaaatt atttgatcga tacttttcat ttagaaagaa cagacacgat
     2401 gatgatcggc gatcgtcgtt tagatatcga agcagggaaa aatgcaggag tcgctacttg
     2461 tctttacgac atcgatcatt ttctgggtga gatcccggca gattatgtgg taggaaatct
     2521 gaatgaaatc cttaccttgc agagcatcat taaaaagtag tatccccttt caaaggagat
     2581 atgttataat tttcataaag gagtgataaa attatatgga aatcagaaga caaaaagaag
     2641 ttgtagaagc atttcattat gatatgagat tgccgaacca agaagtagaa acagatttga
     2701 aagtaggctt ctcgccttta aaagaaacga tcgaaaacta tccgaaagaa catagcatcg
     2761 taggagcacg cttagagttc cgtttagtgt ttgatacata tgttttatct ggaagtgtga
     2821 gtcagatcaa tcatatcctc aatcggaaaa ttgaaggtca aaatgatgtc acacaagaag
     2881 aagtggacga gctagtagca ccgttattcg atatcgtacg ccgaatgtct tatgaggtga
     2941 cagagatcgc cttagatcag cctggggtaa aattgaattt tcaatcagaa aaacaagaat
     3001 agacagtaaa aacatacctg cgatagatta aagctatcac aggtatgttt ttttattact
     3061 aattgtaagc aaaaagaatg tcatttcgat aaaaatcgtc taaaatataa aagtcactga
     3121 aaaaaatttt ttcaggagga tggttgaaga atcattctcg ggaaccttta cttccttcga
     3181 tggacttgtc attaataata tgaggaggag aaaaatgaca acactcatca cagttttagt
     3241 ggttctagtt tttgcggcat tattatatgt gttctatcgt atgcaaaagc gccatacaaa
     3301 attttcaaca cgcgtcttta cagcattagg agttggtatc gtctttggcg gtctgcttca
     3361 attgatcttt ggtgtagacg acaaagtcgt tactcaatca atggaatgga tcgggattgt
     3421 aggtcaagga tatgtatcat tcttgcaaat gctagttatg cctttagtgt ttatttcgat
     3481 cattggtgca ttcacaaaaa tgaaagtttc tgaaaagcta gggaaaatta gtgcgactgt
     3541 attgacttct ttacttggaa caacagctat tgcagcattg atcggaattg gttcaacaat
     3601 gctgttcgga ctccaaggag ctaaattcac acaaggagct gcagaaacag cacgaatctc
     3661 tgaactggca acacgtcagg aaacagttga aaacttatcg attccacagc agattttatc
     3721 ctttatccct aaaaacgttt ttgctgattt agcaggtagt cgtgcaacaa gtacgattgg
     3781 agtcgttatt ttcgcggcat ttgtcggaat cgcttatcta ggcgtgaaaa gaaaagcgcc
     3841 aaaagaagca gcattctttt cagatttagt cgacagtctg tataaaatca ttatgcggat
     3901 cgtgacgctt gttttgcgtt tgacacctta tggagtattt gctttgatga caaacgtttt
     3961 ggcaacaagt gattttgcag ctatcgtcaa tttaggtaaa tttgtcgttg cttcttacgt
     4021 agcattgctt gctgttttga ttgtccactc actgattttg attggtgcaa aagtcaatcc
     4081 aatcaactat ttcaaaaaag cctttccggt attgagcttt gcgtttactt cacgttcaag
     4141 tgctggagct ttgccattga atatcgagac tcagacaaaa gctttaggag tagatgatgc
     4201 aacagctaat ttctcagcaa gttttggttt gtctattgga caaaacggct gtgctggcgt
     4261 ttatccagct atgttggcaa cgatcgtcgc accagcagct ggagtgaatg tctttagttt
     4321 ggaatttatt ttgatgcttg tggcaattgt aacaatcagt tcttttggtg tagctggagt
     4381 cggtgggggc gcaacatttg cttcactgat cgttttaggg gcaatgaact tgccagtagc
     4441 aatcgttggg ttagttatct ctgttgaacc attaatcgat atggcacgta cagcagtaaa
     4501 cgtcagcggt agcatggtag ctggtatcgt gacaagtgca cgcatcaaag atttagatcg
     4561 cgatgtcatc aatgatgatt ctaaagtgat cgatgtgaat gcatagtcaa aaagaggttg
     4621 tgatagaagt ggtcagcttt aagaaataag aagaagtttc ctaaaaatag tttctcaaat
     4681 ttttgtgaaa tttcggctta tttccgagaa gctacttctg aaacaccgtg aataagaggt
     4741 tg
//
LOCUS       DACGMI010000115         4539 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.121, whole genome shotgun sequence.
ACCESSION   DACGMI010000115 DACGMI010000000
VERSION     DACGMI010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.121"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            58..912
                     /locus_tag="IXT46_002863"
     CDS             58..912
                     /locus_tag="IXT46_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4948733.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1009..3258
                     /locus_tag="IXT46_002864"
     CDS             1009..3258
                     /locus_tag="IXT46_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAQ4948734.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3261..4436
                     /locus_tag="IXT46_002865"
     CDS             3261..4436
                     /locus_tag="IXT46_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4948735.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRVTRGAS"
     gene            complement(4439..>4539)
                     /locus_tag="IXT46_002866"
     CDS             complement(4439..>4539)
                     /locus_tag="IXT46_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAQ4948736.1"
                     /translation="ESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1595 a          651 c          823 g         1470 t
ORIGIN      
        1 taataatata aacataataa aacaaaaatt atccaaatct aacataggag ggtggatatg
       61 gaaaattcta tatatttagt aacagaacct aacactcagc tgaaagattg ttactttaat
      121 ttttgtgggt attcaaaaac agaacctaga catagttttg gaccagctat tcgagaacaa
      181 tacttaatac acatagtgct agaaggtgaa ggctattatt caattaatga tcaaaaatat
      241 tttctgaaga aaggccaagg atttgttatc ccaccaggag tatctacttt ttatcaagca
      301 gatgaaaaaa atccgtggtc atatgtatgg ttgggtttaa gtggcaatct tgtagaatac
      361 tatctaaaag aaattggtgt tggaaagaat catcttacct ttaaagtcga aaatttaaat
      421 tcatttaaag gattaatttt tgaaacttta tcgtatgatc aggacaatct agtcagtgaa
      481 ttgtccagac aaaaacaagt ttataaattt ttagaactcc tcttaaattc agctagttat
      541 ctgaacgaag ggataattac taaaaagatg aatccttttg ttcgtcaaac aattgaaata
      601 atacgtgaga atgcgtatca aaaattatct gttaaagata ttgctgtcag tctatcgata
      661 cacgaaaatt atttatcacg attgtttaag aatgatatgg gaatatcaat aaaagagtat
      721 attagtgaaa tcaaaatttc tattgcaaac gatctgttat catcaactga atattcaatc
      781 cagcaaatca gtgacaagat aggattctca acagtacaat ctttttctaa agcctttaag
      841 aaagcaaatg gtgtttcacc gggagtatat cgaaaacgta gattaggtct aggaatcatt
      901 aatggtgaat aaactaaaca tttgattttg ataaatattc gttactttaa acgcttacta
      961 tttatgtgag cgttttttat aatgcaataa agaaacggag gagagcttat gtataaggat
     1021 aatgaaatga atattattta tcgatcagaa aaccaacaat ttcatttgtt taatcaggag
     1081 ataagttaca tttttaagat atcggaagat ggtaaattat tgcatttata ttatggtgag
     1141 aacttaccag ataatgacta tagtcatcta attgagatgc atcatcggcc tatgacaacc
     1201 tatagaaatg aaaacgattt gctatattcg ttagagcact taaaacaaga atttcctgaa
     1261 tatggtacaa cagattttag acatcctgct atttcattac tacagaaaaa tggctctcgc
     1321 ttatcagatt ttgtctatca agggtacgaa gtggaagaag gaaaacctaa actagaaggt
     1381 ttacctgcta cctatgttga taataatgat gaaagcaaaa cattgaaagt ttatatttta
     1441 gattcagtta caaatgttca agtagaatta ttatatacaa tttatagaga ttatcctgtt
     1501 attactcgta gcgcgcgagt tatgaataaa ggaaaagata ttcaaataat cgagaatatt
     1561 agcagtttat cattggattt acccgatgca aattatgaat ggcaacaatt atctggtgct
     1621 tggggtagag aaagaactat taagtcgcgt actttacaac aaggaattca atcaatcgaa
     1681 tctactcgag gtatttcaag ccatcagcat aacccatttg ttactttaaa aagaaaaaat
     1741 actgatgaaa atcaaggaga agctattggt gcagcactag tttactcagg aaacttctta
     1801 attcaagcag aagtagatac atgggatgtt actagactac aagttggcat caatccattt
     1861 ggatttaatt ggaaactcaa tccaggagaa atatttacag caccagaagc gattctggtt
     1921 tattcaagta agggtttaaa tgccatgagt caaacttttc atcaactatt tagaaaacgc
     1981 ttagctcgtg gtaagtggcg agaaaaagac cgtcctgtct taattaataa ttgggaagca
     2041 acatattttg attttgacga agaaaagttg gtaaatattg ctaaaaaagc atttgatgtt
     2101 ggtattgaat tatttgtatt agatgatggc tggtttggag aaagagaaaa cgattgtgca
     2161 ggattaggag attggcatgt aaatcctaaa agactaccta gaggaatcgg cagcctttca
     2221 gaaaaaattc gtagttttgg tatgaaattt ggtttatggt ttgaacctga aatggtgaat
     2281 aaggatagtg agttatatcg cacacatccg aattggatta tttctacacc taatcgaaaa
     2341 cctaatcatg gtaggaacca atatgtatta aattttgggt tagatgaggt tgttgaaaat
     2401 attttcgatc aaatgtgtaa aatcattgat gaatcaaact tagattacat taagtgggat
     2461 atgaatcgtc cattgactga tgtatttgac agtcacttgt cagcagatca acaaggagaa
     2521 gtattccaca gatatgtact aggcgtatat cgcttatatg aaaaacttat aacaaaatat
     2581 cctaacatac tatttgagtc ttgttcatca ggtggtgggc gctttgatcc tggaatgctt
     2641 cactatgcac ctcaagcttg ggctagtgat gattcagatg caattgaaag gttaaaaatt
     2701 caatatggaa ctagtatgct gtatcctctt tcgtctattg gtgctcatgt atcaattgtt
     2761 ccaaatcatc aaacaaaccg tataacacct ataaaaacta gaggaaatgt agcttttttt
     2821 ggtgcatttg gatatgagct tgacttaaat gaattaagtg aaggcgattt gaggattgta
     2881 aaagaacaaa ttgcctttta taaaaaatat agaaccataa ttcataatgg tactttttat
     2941 agactattat caccattcga tgatgataat caaaccgcgt ggatggttgt tagtcatgat
     3001 aagaaaacgg ctattgttgc tcattataaa acattaaatg aggtaaatgc tccttaccgc
     3061 cgactgaaat taaaagggtt agataatgac ggactttata atgtaggaca aaatagtttg
     3121 cgatctggaa tggaattgat gagagcagga ctagtctgtt cagatgcatc tagtggacaa
     3181 ataaatgatc agaatcgacg cccagaaaca tttgattttg attccaagat ttgggttata
     3241 acacaggagg aaaagtagag atgaataacc aaaaaagctt acttcaaaaa ggagcaatct
     3301 taagtatttc actaatgtta acaagctctc aagcaattaa tggtgttatt ccacaaatga
     3361 aacagtcttt ggggatatca caaagtcaaa gtgaactttt aggaactgca ccaagtataa
     3421 ctgttatttt gtttatctta ttatctagtt actttgccaa aagaatagga atgaaaaaga
     3481 caataatttt aggtttatta ttagctggta taggaggaat tattccagta tttacagcta
     3541 ccttccaaac cgttcttatt agtcgagtaa tattaggtgc cggtttagga gtatataatt
     3601 cattggctgt gacatatatc agctctttat actctggcaa tactagagca acgctattag
     3661 gtattagaaa ttcaatggaa gctttaggtc agacaatcct tatttttctt gctggagttt
     3721 tagtgaacat taattggacg gcttcgtttt tagtctatgc aattgcgttt cctgtagctc
     3781 tcttattcgc gctaaaagtt cctgaaatta gagatgaaaa tagtgacata cctgaaaatc
     3841 atgtaaaaga aaagatgaat ccaatggttt ttgccctagt tctatttgca atcttactcg
     3901 taatgaatag tattgctatt tctgtacgat ttgcatcaat tgcaactgaa attaaagggg
     3961 taaactttaa tgctagtaac tatttagctc taatgcctat cttaggaata ctagcaggat
     4021 ttatgtttgg accaataaat aagtggatag gaaaaggaac cctatacttg ggaattatat
     4081 tctttataat ttcaaatttg ttaattgctg tgtcaaacgg taatatgacg ttcctgctaa
     4141 cgggtttatt tttatcaagt ataacaggat catggtgctt cccatttatc tttagtaact
     4201 tagataaagt cactacaaag aatacaatta attttgctac ttcattgatt tttattggct
     4261 gtaatattgg taattttata gctcctattg ctatgcaatt agcacaattt ctaacaagaa
     4321 gtacaaattt gactgctcca ttttttgtat tcgcaggaat atttattgtg atcctatttg
     4381 taacattttt tgcgacaaat aaaaaaaata ctagagtaac ccgtggtgct agttaatttt
     4441 aatatcctaa agaatatctc aaagttcctt caaaacgtcg ttgtgctcga cttaatagaa
     4501 cactgtaagc cagtaatatg ctttcaaatc tactctcta
//
LOCUS       DACGMI010000116         4459 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.122, whole genome shotgun sequence.
ACCESSION   DACGMI010000116 DACGMI010000000
VERSION     DACGMI010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.122"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            220..1194
                     /locus_tag="IXT46_002867"
     CDS             220..1194
                     /locus_tag="IXT46_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4948737.1"
                     /translation="MRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAGQYLFD
                     KELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGAMTICL
                     SNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWETCLNEF
                     DKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFMEMQWIN
                     SNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVLDQADF
                     DLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1176..1637
                     /locus_tag="IXT46_002868"
     CDS             1176..1637
                     /locus_tag="IXT46_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4948738.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1687..2151
                     /locus_tag="IXT46_002869"
     CDS             1687..2151
                     /locus_tag="IXT46_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4948739.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2165..2914
                     /locus_tag="IXT46_002870"
     CDS             2165..2914
                     /locus_tag="IXT46_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4948740.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2914..3744
                     /locus_tag="IXT46_002871"
     CDS             2914..3744
                     /locus_tag="IXT46_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4948741.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3744..4391
                     /locus_tag="IXT46_002872"
     CDS             3744..4391
                     /locus_tag="IXT46_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4948742.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
BASE COUNT         1543 a          577 c          840 g         1499 t
ORIGIN      
        1 cactccttgc attcgttttc ataaatctat tataaaagaa aagactgtag acatcatcca
       61 taaaatggac tttgtctaca gtctggcatt ttattatata aaattgttat aaaaaaattt
      121 ttttgaaaaa tagtattgca aaataaagca atttcataga taataggtat tgtaaagtta
      181 tatgacttta taatacttat tagagtgagg gataaagaaa tgagacaact acacaaagaa
      241 cagattgaaa cagcaatggc agcgttaaag gaaaagacaa ttgatcatgt atattttaca
      301 gcatgtgggg gttcacaagc cgttttaatg gctggtcaat atctatttga taaagaatta
      361 actgtacctt gtcatgttta tactgctaac gaatttaact atgctatacc aaaaggatta
      421 tctgaaaatt ctttagttat cacttgttcc cattctggca caacaccaga aactgtagaa
      481 gcaacaaaaa aagcaagaga atttggagca atgactattt gtttatctaa tgaagaagga
      541 tctcctctat gggaagcagc tgaatatcct gttcactatg attggggtaa agatgttgat
      601 gctagtgatt taaataaagg aattctttat ggtttattat ttaatatttt acttgtttta
      661 gatggctcta aaaaatggga aacttgcttg aatgaatttg ataagttaaa tgatcttgtt
      721 attgctgaaa agagcaaatt tgaaataact gctaaagaat ggggtaaaaa ccaaaaacga
      781 gataaaatta tttacacaat tggtagcggt atcaattacg gagaaattta ctccacagca
      841 gcttgctggt tcatggaaat gcaatggatt aattctaatg ctattcattc tggggaattt
      901 ttccatggtc cttttgaaat cactgattat gatgtaccat tcatcttagt gaaaagtatt
      961 ggagatacaa gatttttaga tcaacgggta gaagacttca ctaaaaaatt cagtaataaa
     1021 ttaatggttt tagaccaagc tgattttgac ttagaatcta tagatagtgt agcgaaagaa
     1081 tatattgcag ctgtacttag tggcgttgtt attcgccaaa tggtagaagc gattgctttt
     1141 gaaagaggcc attccttaga tgttagacgc tatatgtggc aaatgaaata ttaattaata
     1201 ggaggttgca aaagatggca aatcaattat ttcacattgt gattacaaca cattctaccc
     1261 tttgtgaggg ttatttaaag gcaacaaaat taattttaat gaatgacgcc acaggtatta
     1321 gtgctgttcc atttaaagaa aatactagtc cagatgattt tgaggagagt atgaaagaaa
     1381 taattagtca gcatcatttg caacctctaa ttattttaac ggatttaatt ggaggaacac
     1441 ctaataatgt ttctattaaa cagttgaaca acaatagaat tcaaattatt gctgggatta
     1501 atttacctct tttactggag ttattaatgg cccagtcagc tggtaaatct atagaagaaa
     1561 tagattttaa ggaattactg aataactctc aaaaaagtat ggttcatatt aattcgcttt
     1621 taaaagatgt cagttaaggt ggcaatttct attctataaa ttttaaaaat tgaaggagga
     1681 aatagaatga ttaaattagt gcgtgtagac cacagattac ttcatggaca agtaatattt
     1741 tcttggacta aacagtatga tattaaccat attattgtgg ctgataacaa agttccagga
     1801 gatccaatgt ctgtgatggc tttgacaatt gctaaacctg ctgattgcaa attagacatt
     1861 gttaaaatta gtgatgttaa agggattatg gaaacatccc caaatgataa ttacatgatt
     1921 ttaattaaag gacctaagga agcttttgaa ttagttcaaa atttaccaga aattaaagaa
     1981 attaattttg gcggtgtgtc taagaaaagc gagtccaaac aatatggaaa ggcagtcttt
     2041 ttaactcctg aagaattaga agccacaaaa aaaattcttg atcaagaagt gaaaatattt
     2101 gtgcaacaag tcccatcttc aagtattgaa aatgtagatt ttagtaagta aggggggaaa
     2161 ataaatgtta ttaaaagcca ttttattagg tttagttggt gtggtagctg ttattgactc
     2221 caggttaatt ggtcgacaaa atattggtag accactaatt ttgagtacac ttgccggact
     2281 tgtgctaggt gacttgcata cagggattgt tcttggggca tctttagaat taatttctat
     2341 gggattcgtc tcaattgggg cggctggacc tcctaatatg caacttggta gtattattgc
     2401 cactgctttt gcaattttaa ctaatagtag tacagaaaca gccttaacaa tagctatccc
     2461 agtggctgta gctggtgaat ttatgagtat tatcatgcgc atgataattg ctcaatttgg
     2521 acatgctgca gataaagcca ttgaaaataa taaatttaga aaagctcaaa ttattcatat
     2581 ttattggtca tttattttta atgcttttgt ttactttatt ccaatctttt taacagtata
     2641 ttttggtgct gacgttgtgg cagatttagt agataaaatt ccagaaatga ttacagacgc
     2701 cttgactgtc tctggaaata tgctttccgc attagggttt gcaatgctat taagcacaat
     2761 gttgagtaaa aaattatatc cttactttat ttttggattc tttattgttg cctattcagg
     2821 tctttcacta attggcgtga caatttttgc agctctgatt gcctttgtaa tggatcaagt
     2881 taaatatgga aaaagagaag aggcgcatgg ttaatggaaa atagtacaga aaaaaaacgt
     2941 ttaatcacaa aaaaagatct taataagatg tgtcttcgtt catggacaat catgtgttcg
     3001 tggaattatg aaagacaaat gcatatggga tttatgtatg ggatggcgcc aattttaaat
     3061 aaagtttata aaaatgatga agagaaaaaa agagaagctt atactcgtca tatggcattt
     3121 tttaactgta cgcctcaaat gacttcattt attatgggac tttgtgcttc tatggaagaa
     3181 caaaatgctc aagcagaaga aggaaacttt aatactgaat ctatctccat gattaaaacc
     3241 agtttaatgg gtccttttgc tggaattggt gattcatttt tccaaggtac tttaagaatt
     3301 attacatttg ggattggatt gtcttttgct aagcaaggta gtattttagg accgatttta
     3361 gctgttggcc tttttgctat accttctatt ttagctgttt tttacggcgg taaattagga
     3421 tatgagtctg gcaataaata ccttactaaa ttgtatcaag aaggtcttat ggatcgagta
     3481 atgcaatttg cttctatcat tggtttggct gtagtaggtg gaatggtggc tagcatggtg
     3541 ccaattgtca cccctttaaa attcactaca gggggaacag aacttgtttt acaagactta
     3601 cttgattcca ttattcctgg attattacca cttgtatgta ctttgggaat atataaattg
     3661 attaagaaaa atgttagtac aaatatgctc ttattaggtt gtattttggc agggtttgtt
     3721 ttaagtataa taggtatctt ataatgatta aggctctaat ttttgatatg gacggagttt
     3781 taattgatag cgagattatg tatcaaaagt gggtatttaa ttttttaaaa caagaaaatt
     3841 taagctatcc tttgtattct tatcaaaaaa agattggaac tacagcaagt atttttgatg
     3901 atatagaaaa gtacaatgag ggatgtaaca gtttagaatt gaagggaaaa tttactaaat
     3961 attggaaatc gcaaaagatt gattacttgg atatttttcc taatatacta attgaacagc
     4021 ttgaatggtt aaaaaagaaa aaaataaaaa tggcaattgc ttcttccagt ccaatggata
     4081 ctataaatga agttgttacc acttgtaaaa tagagtcata ttttgattgt ttaattagcg
     4141 gaagagattt gccagaaagt aaacctaatc ctactatatt ccttaaagct tcagaacagc
     4201 tcagaattcc agttgaagaa tgtctggtga tagaagattc ttataatggt ataaaagctg
     4261 gtaaaagagc aaatatgaag gttcttgcaa ttaaagataa acgtttttct caagatgtaa
     4321 gtctagcaga tgatgttatt tacgatatta aatatctgcg acaagaagta caggtgaaat
     4381 ttggaatata aataagtttt ttgatgtatt tagagaatat tagtaaaaat aaaaatcatg
     4441 cccaaatcta atcaaaatt
//
LOCUS       DACGMI010000117         4446 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.123, whole genome shotgun sequence.
ACCESSION   DACGMI010000117 DACGMI010000000
VERSION     DACGMI010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4446
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.123"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            2..74
                     /locus_tag="IXT46_002873"
     tRNA            2..74
                     /locus_tag="IXT46_002873"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="IXT46_002874"
     tRNA            78..150
                     /locus_tag="IXT46_002874"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="IXT46_002875"
     tRNA            155..225
                     /locus_tag="IXT46_002875"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="IXT46_002876"
     tRNA            238..311
                     /locus_tag="IXT46_002876"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="IXT46_002877"
     tRNA            323..394
                     /locus_tag="IXT46_002877"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     gene            871..1185
                     /locus_tag="IXT46_002878"
     CDS             871..1185
                     /locus_tag="IXT46_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4948743.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            1201..1587
                     /locus_tag="IXT46_002879"
     CDS             1201..1587
                     /locus_tag="IXT46_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4948744.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            1616..3001
                     /locus_tag="IXT46_002880"
     CDS             1616..3001
                     /locus_tag="IXT46_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAQ4948745.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            3004..3156
                     /locus_tag="IXT46_002881"
     CDS             3004..3156
                     /locus_tag="IXT46_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4948746.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            3179..4384
                     /locus_tag="IXT46_002882"
     CDS             3179..4384
                     /locus_tag="IXT46_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4948747.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
BASE COUNT         1410 a          821 c          974 g         1241 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaat
      541 agcataaaaa tctagttatc cgcataaaaa ctggacttat cacactttat caaggtcaaa
      601 accactcaat ttactactaa tttactactt atgaatgagc tttgatacga cgatttatcc
      661 ttgaaaagtg aagatataaa gatacttcca ataaaatttg aatatttaat aggtagacac
      721 ttcaaaaaat gaggtgtcta tttttttacc cgattttgaa aggaagtgaa cttatgaaaa
      781 caaaaaatca agaatcaaaa ggtcgttccc cactctttaa gaccatcaaa cattcattca
      841 gccaataaaa aagaaaggat aggtaaaaat atggaactta aatttgtgat tcccaacatg
      901 gaaaaaacat tcggcaattt agaatttgct ggcgaggata aagtcgttca gcgaagaatc
      961 aacggacggc taactgtctt atcaagaagc tataatctct attctgatgt tcaaagagca
     1021 gatgatattg tggtggtgct tcctgctgaa gctggcgaaa aacatttcgg ctttgaggaa
     1081 cgtgtgaagt tagtcaatcc acgtattacc gcagagggct acaaaatcgg cactcgtggt
     1141 tttacaaatt accttttaca tgctgacgac atgataaaag aataaagaaa gagaggaaaa
     1201 atgatgagat tagcaaatgg cattgtatta gataaagaca cgacttttgg agaattgaaa
     1261 ttctctgctc tacgtcgtga agtgagaatc caaaatgaag acgggtcggt ttcagatgaa
     1321 atcaaggaac gtacctatga cttaaaatcc aaaggacaag gacgcatgat tcaagtaagt
     1381 attcctgcca gcgtgccttt gaaagagttt gattataacg cacgggtgga acttatcaat
     1441 cccattgcgg acaccgttgc tactgccacc tatcaaggag cagatgttga ctggtatatc
     1501 aaggcagacg atattgtgct gacaaaggat tctagttcat tcaaagctca accacaagca
     1561 aagaaagaac cgacacaaga caaatagtcg ctaggtagaa aggagacttt ttcgcatgaa
     1621 acagcgtggt aaaaggattc gcccatctgg taaagattta gtctttcatt ttacgatagc
     1681 gtcactcctg cctgttttcc tgctggttgt cggactgttt catgtgaaga caatccagca
     1741 gatcaactgg caggatttta acctatcaca agcagataag attgacattc cctatttaat
     1801 tatcagtttc agtgtcgcaa ttcttatctg cttgctggta gcgtttgtat tcaaacgggt
     1861 tcgctatgat acggttaaac aactttacca ccgtcaaaaa ctggcaaaga tgatacttga
     1921 aaacaagtgg tatgaatctg aacaggtcaa aacagagggt ttctttaaag atagtgctgg
     1981 tcgtacaaag gaaaagataa cctacttccc taaaatgtat tatcgactta aaaatggctt
     2041 gatacagata cgggtggaaa tcacgctggg aaaatatcaa gaccaactct tacacttgga
     2101 aaagaaatta gagagtggct tgtactgtga gctgacggat aaagagttaa aggattccta
     2161 tgtggaatat actttgctct atgacaccat agccagtcgt atttctattg atgaagtaga
     2221 agctaaagat ggtaaacttc gcttaatgaa aaacgtatgg tgggaatatg ataagctccc
     2281 tcatatgttg attgctggtg gtacaggtgg cggtaaaact tactttatac tgacactgat
     2341 tgaagccttg cttcatacag attcaaaact gtatattctt gacccgaaaa atgctgacct
     2401 tgcggactta ggttctgtga tggcaaatgt ctactataga aaagaagact tgctttcttg
     2461 cattgaaaca ttctatgaag aaatgatgaa acgtagtgag gaaatgaagc agatgaagaa
     2521 ctataagact ggcaaaaatt atgcttactt aggtctcccg gcacacttct taatctttga
     2581 tgaatacgtc gctttcatgg aaatgctggg aacaaaagaa aacaccgcag ttatgaataa
     2641 gctgaaacag attgtcatgt taggtcgtca agctggcttc tttctaatac tggcttgtca
     2701 acgtccagac gcaaaatatt taggcgacgg aatccgtgat cagtttaatt tcagagtggc
     2761 tttaggtcgt atgtctgaaa tgggctatgg catgatgttt ggcagtgacg tacaaaagga
     2821 tttcttctta aagcgaatca aaggtcgtgg ctatgttgat gtaggaacaa gtgtcatatc
     2881 agagttttat actccccttg taccaaaagg atatgatttc ttggaggaaa ttaaaaagtt
     2941 atccaacagc agacagtcca cgcaggcgac gtgcgaagcg gaagtcgcag gtgtggactg
     3001 atcttgctgg ctggtgtggc aatagccacg ccagcactta accccccgta tctaacaggg
     3061 gggtacaaat cgacaggaaa cagtcaaaaa aacattagaa aatcctttgg ttacaaggga
     3121 tttacaaaat ttcagcgtat gtcaaatggg ctttaaaagt tgacatacgc ctttttgatt
     3181 ggagggattt ttactgaatg aacaaacttg gttacagcat ttaaaagaaa aacgcttggc
     3241 ttatggacta tctcaaaacc gtttagctgt tgcgactggt attacaaggc agtatctaag
     3301 cgatattgaa acaggaaaag tcaagccatc agaggattta cagcagtccc tttgggaagc
     3361 tctggaacgc ttcaatcccg acgctcccct tgaaatgctg tttgattatg taaggattcg
     3421 ctttccgaca acagacgtac agcaggtggt cgaaaacatc ttacaactga aactgtccta
     3481 ttttcttcat gaggactatg gtttctattc ttattcagag cattatgctt taggcgacat
     3541 attcgtcctt tgctcccatg aactggacaa aggagttctg gtggaattga aaggtcgtgg
     3601 gtgcagacaa tttgaaagct atcttctggc acaacaaaga agctggtatg agttctttat
     3661 ggacgttttg gtggctggcg gtgtgatgaa acgccttgac cttgccatta acgataagac
     3721 agggattttg aatatccctg tactcactga aaagtgccaa caggaagaat gtatctccgt
     3781 cttccgcagt tttaaaagct atcgcagtgg cgaactggta cgcaaagagg aaaaggaatg
     3841 tatgggaaac accctctata tcggttcatt acaaagtgaa gtttatttct gtatctatga
     3901 aaaggactac gagcagtaca agaaaaatga tattcccatt gaagacgcag aagtaaaaaa
     3961 ccgttttgag attcgattga aaaatgagcg tgcctattat gcagtccgtg atttactcgt
     4021 ctatgacaat ccagagcata ccgcctttaa aattatcaat cggtatatcc gttttgtaga
     4081 taaagacgat tccaaacctc gttctgattg gaaactgaat gaagaatggg cttggtttat
     4141 tgggaacaat cgtgaacgat taaaactaac cacaaaacca gagccttact ccttccaaag
     4201 gacgctgaac tggctatctc atcaagttgc cccgacctta aaggttgcga ttaaacttga
     4261 tgaaatcaac cagacgcagg ttgtaaaaga cattctcgac catgcgaaac tgacagaccg
     4321 acacaagcag attttgaagc aacagtcagt aaaagaacag gacgtgataa caacaaaaaa
     4381 ataactcaaa tacaaattca ttgaatatag agaggagaac atttttatga attttggaca
     4441 aaacct
//
LOCUS       DACGMI010000118         4375 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.124, whole genome shotgun sequence.
ACCESSION   DACGMI010000118 DACGMI010000000
VERSION     DACGMI010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.124"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(83..1051)
                     /locus_tag="IXT46_002883"
     CDS             complement(83..1051)
                     /locus_tag="IXT46_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAQ4948748.1"
                     /translation="MSKNGIIVNEWENLTALSNRRLNVQNMYTPLKMQWSIDRITIVG
                     KLKENIYYHTQNDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQYEENIAYIEILKW
                     QDGKGRIDFNPNKIGHFLASSMKNFIHDLFLEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRLYNKKLEQETKRKIVPPEIETWWRLELQ
                     LRRGKATDWHAMVHESLNSFASPHFLPLDVKTNDKVMIFGLIANPEMWGFLERRMKYK
                     LRDILKRESQNDELTNHLRETFSESADVLKKELDTWLQGLDVTEEE"
     gene            complement(1498..2904)
                     /locus_tag="IXT46_002884"
     CDS             complement(1498..2904)
                     /locus_tag="IXT46_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAQ4948749.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKTNDWHKHIDFTKSDEN
                     IYLEQTNLADKYEELFGEVVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     ILDDFQTNRADGSSTGISKQQAEQNRVIANKILVQYYKEFQERNPNLAVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALVQQGIHADKDNGRVLFNNFRNQEVDSIE
                     RLMNDYGWKRDIVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYIYRQREE
                     NERDKALMASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQRKLERSEDEIEW"
     gene            complement(3127..3489)
                     /locus_tag="IXT46_002885"
     CDS             complement(3127..3489)
                     /locus_tag="IXT46_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948750.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPNESDGLLGVIPSKK
                     SQMSESKFTSMFNDVSLR"
     gene            complement(3493..3801)
                     /locus_tag="IXT46_002886"
     CDS             complement(3493..3801)
                     /locus_tag="IXT46_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948751.1"
                     /translation="MDKIDLREETVDRIELMYERLADYLNLPDEDNYSEMLERMMDVL
                     NSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQISVINSKEKEM
                     "
     gene            complement(3810..4229)
                     /locus_tag="IXT46_002887"
     CDS             complement(3810..4229)
                     /locus_tag="IXT46_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948752.1"
                     /translation="MTDLPEKMTIKNLADELGISKNTVRNQLVNAGYDLARYKDNGVI
                     MLDKELIGVVRSIYRSKGGQLTGDLPVNDAGNDFPLEKENEFLREQLAEKDRHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            complement(4222..4362)
                     /locus_tag="IXT46_002888"
     CDS             complement(4222..4362)
                     /locus_tag="IXT46_002888"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948753.1"
                     /translation="MSGKLLDVTQYELILKNNKIDSPIIIPKHAVKYVYGVAESNGED
                     ND"
BASE COUNT         1234 a          995 c          619 g         1527 t
ORIGIN      
        1 aaaaaaacaa cgacaacgtt atcacctgtt aaattcacca accaattttt cttaccaaaa
       61 tgcttttgtt tttctgccat tcttattcct cctccgttac atctaaccct tgaagccaag
      121 tgtctaattc ttttttcaaa acatctgctg attccgaaaa tgtttctcgt aaatgattcg
      181 tcaactcatc attttgactt tctcttttca aaatatctct caatttgtat ttcattctac
      241 gctctaaaaa cccccacatt tcagggttag caatcagtcc aaaaatcatc accttatcat
      301 ttgtttttac atcaagtggt agaaaatgag ggctagcaaa actatttaaa ctttcatgaa
      361 ccattgcatg ccaatctgtt gctttcccac gccttaactg caattccagt cgccaccaag
      421 tttctatttc tggtggcaca attttacgct tggtttcctg ttccaatttt ttgttgtata
      481 gccgaatctg gcgttcgctg gcacgactgc cccaataagc tgtttccagc ttcccagacc
      541 gcccataaat tggcttgaaa gaaacaggat caaccactcg atattgtgta ataaactcat
      601 caggcacatc gataatatcg caagcaatat ccgcacgtga gaaatgtggt tctagaaata
      661 aatcatgaat gaaatttttc attgaactag ctaaaaaatg accaatctta ttcgggttaa
      721 aatcaatccg ccctttgcca tcttgccatt tcaaaatctc aatataagca atattttctt
      781 cgtattggtc taataattgc cagccgttat tcccaaccgc ttttaaatag ccattgcctt
      841 cattcacccg cattaattgc tcaaaatcta aaatcaacac atcattttga gtgtgataat
      901 aaatattttc cttcagtttt ccaacgatag taattcggtc aattgaccac tgcattttta
      961 agggggtgta catattttgt acatttaacc gcctgttaga tagggctgtt aaattttccc
     1021 actcatttac gattatgcca tttttactca aattttgttc ctcctcaaag aaaaagagac
     1081 ttctggaaag aattttcaaa agttcacgta actcttaaaa attcattacc aaaaaatctc
     1141 tagtcttgaa gaaatctaaa aatattcgta taatgattaa gaagttacgg agctagtgcg
     1201 attagtttcc gtaaaggtcg agaacgttgg tagcgttgct cgactatttt tttactcttt
     1261 tttcagttca tttgtttgct aactcaataa tagcacttct ctttagctat gcaaatatcc
     1321 aaaaaataaa accgcaccct ttgaaaaggg cgcccccaaa cttcgctaac gctaggttgg
     1381 ccaaaaaatg gactggccat tttttagcaa atgtcagctt aataggctag tggtttagcc
     1441 gtcaactcct tatcctcggc acaaaccgcc tccggtaccg ttgactgcac atcgtaacta
     1501 ccactcgatc tcatcttcag aacgctctaa tttacgctgt gagacgtttt gacgataaaa
     1561 taaggttttc tcctgctcta acacttctaa ttcctcagaa agccccatat ccttttctgc
     1621 aagaccaaaa cggatagaca aacgagtgat cgatttttga aatgcgtttt ttaatcgctc
     1681 taaacgctgg cgtaaagagc gattttcttc tttcagcttt ttattttcca cttgtaaatc
     1741 tgctaattgt tttctaccag acaaatgacg ctcttcttcc aatgtagcta catactcatt
     1801 taattctgta ttttgctcaa gcatctgtaa atattgctca ctcatgttat cagcatttct
     1861 cttggcattt gttgctctcg tagctcgttg atacaaatca acaaaatcat tcccagataa
     1921 atgatacgaa ccatcaggaa gcctcttgaa actttctaaa ggaaccatat ctttttggaa
     1981 aatgaccgcc atctcttttt ttacattcag catatttttc ttctcttctt caatcttcgc
     2041 tctctcagaa gccatcagag ccttatcacg ctcgttttct tctctttgcc tataaatata
     2101 cctcaactca tcagaaacgc tctcacgctc ttttacagcc gtttggcgca attcagaaat
     2161 ttcactcatg atttctttgt attcgtgaat atctttaatt ttgttggtac cgacaatatc
     2221 ccttttccaa ccgtaatcat tcattaatcg ttctatagag tcaacttctt gatttctaaa
     2281 attattgaaa agcactcgac cattatcttt atcagcgtgt atcccttgtt gaaccagtgc
     2341 tttattaaag ctcggctgct tttgaacacc ccgtttataa ccttcagcaa ccggcacaat
     2401 attcaagtgc aggtgcggac ttatttcgtc attatgaata acagcattat aaacagccaa
     2461 attagggttt ctctcttgaa actccttgta atactgaacc aaaattttat tggcaatcac
     2521 tcgattttgt tcagcttgtt gtttcgatat gccagtagaa gaaccatctg ctcgatttgt
     2581 ctggaaatca tctaaaatgc ctatttgcac aataaattct cgttgaggtt ccaacttttt
     2641 atccttgcgc actttcgcta aatagtcctc gatttttcta tcggctcttt tttgtttcgc
     2701 attatatttt tctaccactt cgccaaacaa ttcctcatat ttatctgcta gattcgtctg
     2761 ctctaaataa atattttcat ccgatttcgt gaagtcaata tgcttatgcc aatcattggt
     2821 tttctggcta tcagttaact cacgattatt atgagaaata cttgtattct tcgttccttt
     2881 tttaaatgaa atactaaacc ccaagttaaa accctccttc gcgctgtcgc taataaaaag
     2941 agtgtaaacc tttctgttac tctttgtcaa agagtaaaca ttttcctaat tgtgacatgg
     3001 ctgtcacaat tccaaatgct ctccgagggt attcgctgtc acaagtgaca acgaaaaaag
     3061 gagccgaaag cgtgtcacgc tctcaactcc ttttacgctt tattttgctt cacgcaaaat
     3121 aatcgcttat cgtaaactca cgtcattaaa cattgacgta aatttactct cactcatctg
     3181 acttttttta ctcggtatca ctccgagtaa gccgtcagat tcattgggat aatctcgttc
     3241 gcttggcgct gatttttcat cagcaagcca ctcattatcc actgattttt cgtgttgctg
     3301 atcgtcagaa atcgacgata gccaccgctc aaaatcagca aaagtttcaa acccaaaacg
     3361 cttgcgaaga gccttgccca ttgcagcatt ttctttctca atcaagcgtt ttttctgttg
     3421 gcgaagtttc gcttgttctt tttttaattt ttcttcttgc gctttaatat ctgctaaagt
     3481 cattcccata aactacatct ccttttcttt ggaattaata acggaaattt ggtttaactg
     3541 cataacatga ctcattaatt tcaaccaaaa ttctttttct gattcatcag ttgtttgcgc
     3601 taaatgctta tgaacaaatt cattagtcaa aactgaagat tttgctagat cagcattgat
     3661 aaccgagttg agaacatcca tcattcgttc aagcatttca ctataattat cttcatccgg
     3721 caaattcaaa taatcagcta accgttcata catcaattca attctatcga ctgtttcttc
     3781 tctcaaatca attttatcca tgtcacacct cacttccaga attgccacca ttttcgattt
     3841 tttaattctt gattttctag taacaactga tcgttttttt gttgctgaag caaagtcaat
     3901 ttttgttggt cacgaatcat ttccgttaat tcagaaatat gcctatcttt ttccgctaat
     3961 tgttcacgca aaaattcatt ttctttttct aacgggaaat cattgcctgc atcattgacc
     4021 ggtaaatcac cagtcaattg accacctttt gaccgataaa ttgaccgcac aacaccaatc
     4081 aattccttgt ctaacatgat aaccccatta tctttatacc gagcaaggtc ataacctgca
     4141 ttgaccagtt gattgcgcac tgtattttta gatataccca actcatcagc aaggtttttt
     4201 atggtcattt tttctggcaa atcagtcatt atcttctccg ttactttcag ctaccccata
     4261 aacatattta acagcatgct tagggataat gattggggaa tcaattttat tatttttcaa
     4321 aatcaactca tactgcgtta catcaagtaa cttaccggac atttttttgc tatcc
//
LOCUS       DACGMI010000119         4104 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.125, whole genome shotgun sequence.
ACCESSION   DACGMI010000119 DACGMI010000000
VERSION     DACGMI010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4104
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.125"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..542
                     /locus_tag="IXT46_002889"
     CDS             <1..542
                     /locus_tag="IXT46_002889"
                     /inference="COORDINATES: protein motif:HMM:NF024997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4948754.1"
                     /translation="SKENLLNQDFSTETICEKWAADITYIPTKKNGWCYLSSIMDLHT
                     KRIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWLKTNKI
                     RHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNRNRIHS
                     SIHYLTPQEFEELAKEKMA"
     gene            complement(1015..1587)
                     /locus_tag="IXT46_002890"
     CDS             complement(1015..1587)
                     /locus_tag="IXT46_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4948755.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1603..2208)
                     /locus_tag="IXT46_002891"
     CDS             complement(1603..2208)
                     /locus_tag="IXT46_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HAQ4948756.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            complement(2329..2586)
                     /locus_tag="IXT46_002892"
     CDS             complement(2329..2586)
                     /locus_tag="IXT46_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAQ4948757.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(2579..2848)
                     /locus_tag="IXT46_002893"
     CDS             complement(2579..2848)
                     /locus_tag="IXT46_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4948758.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(2979..3158)
                     /locus_tag="IXT46_002894"
     CDS             complement(2979..3158)
                     /locus_tag="IXT46_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948759.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(3539..>4104)
                     /locus_tag="IXT46_002895"
     CDS             complement(3539..>4104)
                     /locus_tag="IXT46_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948760.1"
                     /translation="EQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETEK
                     YIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDD
                     YYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYT
                     YDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         1225 a          830 c          622 g         1427 t
ORIGIN      
        1 tttcaaaaga gaatctctta aatcaggact tttctactga aacgatctgt gagaaatggg
       61 cagctgacat tacgtacatt cctactaaga aaaatggttg gtgttactta tcttcaatca
      121 tggatttaca cacgaaaaga attattagtt atacattttc aaaacgaatg actgtggatt
      181 gtgtcattca aacattgaat aaagcaaaaa tacattatca cattccagaa ggaatgattc
      241 tacacactga cttgggcagc caatacacag caagagaagt ggaacaatgg cttaaaacca
      301 acaaaataag gcattcttat agtagaaaag gaacacctta tgataatgct ggaatcgaat
      361 ctttccatgc ctcattgaaa aaagaagaag tctacacgac tagctactca gattttgaag
      421 aagcaaatcg agcgctattt agctacattg aaggatttta taaccgaaat cgaatccata
      481 gctcgattca ctatctaacc ccacaggaat ttgaagaatt agcaaaagaa aaaatggctt
      541 aaccgtctct actaaaatgt gtccaagata ttgactcaaa tccagtaata tcacaatagg
      601 aatgctgttt attatattag cagcagtgct gatttttatg atagttattt ggttcttaaa
      661 tgaaagatct aaagacaatc aacaccgtag ggatatggag ataaaatcaa tagagtcaat
      721 agattattta tcgataataa cactaaaaaa gccacgttcc taaacgtgac ttacgctgaa
      781 cgatatgtgt tgtttggtag acgaacaaat cgttcattat aaatatatga tggtatccta
      841 atatagtaag cgtggctagc atacctttaa ttactttacc ttttacagtt accatacaca
      901 ttttttgagc agaaatcaag taaataaaaa aatattatat ttcacaacat gctaatagac
      961 tcatatctag aacgcattaa gtatttacct gtctggttcg ctgagacttc ttttttaact
     1021 ttcttcaatt ttcttcttta ttctaaaaag cgtactgcga ctgaaaccgg ttatagcttc
     1081 aacttcctta tacgatttac ctgaagtaag cagttcatat gcgtgcctct tcttcggtgt
     1141 gattgttgct ttcggacgtc cttctctgaa attaggatta ttctttcttg caaacatttt
     1201 tccttcttgg gtacgttcca caatcatatc acgttccatt tctgctacac tcaacaacgt
     1261 ccgtgtcacc attcgcccca tggacgtatt ttcaatcgtt cctagattca aaaccttgat
     1321 cgttacgtta tcatcgagta aaggttcaat gatctctaat gcttctctcg tgttacgagc
     1381 aaatcgatca agcttcgtaa caactatttc atctccaggc ttcagaccag ccaacagctg
     1441 attgaatttt ggccgatccc gttttgtacc cgtaaatttt tctgaaaaaa tattcttctt
     1501 ctctacgccg ttctcaagca actgttgaat ttgttctttt gtactttgag aagcggttga
     1561 gacacgtgca tatccatatt tcgtcatttg gtccacctac ttttacaaat catctatcgt
     1621 atactcagaa tacccttcat agaaatagct gacatcgatt cctttcatat ataactcgcg
     1681 atcgtcaatt ttatcagtca gagcattgga aattagatag cgtatttcca aatcgtttat
     1741 gggacttcgc tccattgcag aaagatagtc tgctttatcg attaagttcc aatctacaac
     1801 tttttgcaat tcttccttta aaatgagatc cagccaaatt ctagtacttc ggccatttcc
     1861 ttctcgaaat gggtgagcga tattcatctc cacatatttc ttgataatct cttcaaaaga
     1921 agtttgtggc atctgatcaa tatgctgtaa cgaatgttct aaatacataa ctggtgcaaa
     1981 tcgaaaattt ccttttgcaa tattgaccga tcggattttt ccggcaaaat cgtaaatatc
     2041 cgaaaataga aattcatgaa tttcagataa acctttaaat gtaccaactt cgatttcatt
     2101 tatttttcca caatcgtaca attctttcgc tttttgttta ctgagttttt cttcaacctt
     2161 agccaactca acttgattgg ttaatcccaa tttattctct aaaatcatgc gaaatctcct
     2221 taactttatg acataagttt atgaaacact ctcaacccca ttatatcgcg attttgttta
     2281 tgtgtcaaaa actattaagt ttctgaccct ttccttactt ccgattggtt aatagtgatc
     2341 ttttgcagaa taaataaata tcgtttcatt ttcaactcta tatatcagtc tatgttcatc
     2401 tgtaattctt ctggaccatt ttccagataa atcatgcttt aatggctcag gttttcctaa
     2461 tccagcaaag ggggaacgat cgatatcttt tattaacttg ttaatctttt ttatattgct
     2521 tttgtttcct tgctcatgcc aataaagata atcatcccaa gcatcatcag accaagcctt
     2581 aatcatcaga ttcaacctcg attaagtcat gtgttttaaa tgcacctttg gagaattgtt
     2641 catctcctcg acgaattttt tccatgacgt aattattaga aagtgttctc aacgtttctt
     2701 gcatagaatc ataatctctt tttgataata caacaactgt atcttctaca tctttacttg
     2761 ttacaataag tgtttcagca tcctcattaa cttgtttcat ataactacgt aaattttggc
     2821 ggaaatttga ataagctact gcttccattc ctttcacccc ttatttattt ctataaaaca
     2881 attgtacatt atattgtaca attaagcaaa tgattaatat tctaacttct tataattaaa
     2941 agtgctatca cttttagttt ttaggataaa aagtgacgtc actttttgag tgctggtacc
     3001 tcaaatcctg ctttttcttg ggcaatcaat aaatctaacg caatacacat aatcctggat
     3061 tcacttttgc cgtacttctg ctttagttgc tgcaattctt tttgtctctt ttcatccaac
     3121 gtaacgggta accgtttatt tcctattgca attggcatta gtactctctc ctttcatcga
     3181 aataacccta tgaaaaatat ggctgcaatc atcttgaata gtagactcac aagggctaat
     3241 acaaagcgcc aaaagatcaa acaaaatacc agtattgcca aaaatactac gaagtttaaa
     3301 tgcacagctg cagcatggcg cataagtatt tcgccaacaa ataggactaa caatagagga
     3361 atgattttat tcatatggat ctccttcttt ctcttaggtt atcgggtgtt gcccgcttat
     3421 ttcgcaccac ctaagcggcg ggggcggttg gagcgattgg tgcgaaataa gaaccattcc
     3481 cttagttact aggttttttg tccttatttc acacattctc acttttcggt ataaatgatt
     3541 attgcctttt tttcctttca aatcgttgat atggcattcg tttacggtca agttcatttt
     3601 ggatttcttc tgtatcgtcg taagtatagg tgtctaaaaa atcagttaaa gtcgtgtacc
     3661 agtcgtcgcc tgggttatct acttcttcta catattccct caaaaatgct tcgggtacag
     3721 cgagttcata atccattccc attaacacga tagattccgt tccacacgtc aaaaatctag
     3781 taaatacaag gtaataatcg tctatcgtcg catctttgct gtttagctct tccatttctt
     3841 cttccattaa ttccatgctc tcaaaaattg aataatattc tgattctgag taatagtgtt
     3901 tcctgcaaat cgtgtagctg acaaagtttt cgaccagctc actcctttct aggtaaacat
     3961 tcatgatgta tttttctgtt tctagtcgta gaagctccgt tccttttttt accgtttcag
     4021 gacgacgttt atacacgtct aaacgattat ggctgactgt gaccttcgtt tgactcgttt
     4081 cactttccaa atacaattgt tctt
//
LOCUS       DACGMI010000120         4101 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.126, whole genome shotgun sequence.
ACCESSION   DACGMI010000120 DACGMI010000000
VERSION     DACGMI010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4101
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.126"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            120..1469
                     /locus_tag="IXT46_002896"
     CDS             120..1469
                     /locus_tag="IXT46_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4948761.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1597..2187)
                     /locus_tag="IXT46_002897"
     CDS             complement(1597..2187)
                     /locus_tag="IXT46_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAQ4948762.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2334..3686
                     /gene="brnQ"
                     /locus_tag="IXT46_002898"
     CDS             2334..3686
                     /gene="brnQ"
                     /locus_tag="IXT46_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAQ4948763.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1185 a          747 c          792 g         1377 t
ORIGIN      
        1 tttttatgaa ttactcataa aaggtaaatt tctgaaaatt ttggaatctt agttgtgttt
       61 ttcagaaaac tctcttaata tggaagtaat taaacttttt tagttaggat gatttaaaaa
      121 tgaatgaaga gcaagaactg cagcgtggac tgaaaaatag acatgtccaa ctgatttcta
      181 ttggcggagc gattggaacg gggttgtttt taggttccgg aaagtctatc cagctagctg
      241 gcccttcgat attgctcgcc tatcttatta ctggatgcat ctgttttttc attatgcgtg
      301 cgttaggcga acttctgtta tcaaacacca ataaccattc ttttctggat tttgttgcag
      361 aatatcttgg caaaaaagcg gctttcatca ctggctggac gtattggttc tgctgggtat
      421 cgattgcaat ggccgattta acagccatcg gaatgtatgt acgctactgg gcgcctggtg
      481 ttcctcagtg gcttcctgaa ctgattgcat taggtcttct tctttgcttg aatatggtgg
      541 ctgtctcatt gtttggtgag ttagagtttt ggtttgcatt gatcaaagtt gtagcgatca
      601 ttgcctttat cctcgtagga gcttatatga tcctcaccca ctatacgaca gatattggca
      661 cagccagtat cacgaatcta tggtctcatg gcggattctt tccaactggt gcaaaaggat
      721 ttatcttagc tttccaaatg gtaacctttg cttttgctgg gatagaatta gttggattag
      781 tcgctggaga aacagaaaat cctgaaaaag tgttgccgga agctatcaat aatattccta
      841 tcaggatcat cttattttac ttaggatctc tttttgtcat tatggcaatc tatccatgga
      901 acagcttgaa tccagataac agtccatttg tagaagtatt ttcggaaatt gggatcacga
      961 ttgctgcttc cttgatcaat ttagtcgtat taagtgcagc agcttctgcc tgcaacagtg
     1021 caatatatag tacaggacgt atgcttcgtt ctttagcgca agaaggcagt gcccctaaaa
     1081 aattcaaaaa gttaacaaca catcatgtgc cagggaatgc tttgacattt tctactatcg
     1141 tcattttcat ttctgttatc ttgaattacg tgatgcctag tgaagtattc acactagtaa
     1201 gcagtattgc cactacttgt ttcttgttta tctggagtat gcttgtctac acgcacatga
     1261 aatatcgtaa aagtatcctc ggcaaaaaag ctcattcatt taaaatgccg ttgtacccat
     1321 ttagtaatta tctggtattt ctttacatgg cctttgtgtg tgtcgtcttg ttcctaggaa
     1381 aagatacgag aatcgcttta ttactaacac ctgtgtggtt cttgcttcta ttactaatct
     1441 atcatatgaa atatgaacgt aagaagtaag aaagtagttg tgacagaagt ggtcagcttc
     1501 gagaaataag aaggaattta cgaaaattgc ttcttaaatt tttgtgaaat ttcggcttat
     1561 ttcttggaga taaaagcttc tgtcccagcc tcttttctat ttccccggaa acaaccgctg
     1621 ataataggca tctgcttttt tataggaaaa aatccaaata ccagatacaa aaaaacgtcc
     1681 gaataacccg atcaacggta caaaaaagac accggcaatc aagcataagt taatcatcat
     1741 ggagataaga cttcgacggt cctttgacaa aactctcacg acatgggaat ctggtttatt
     1801 tgctttcatg atttgcctca tcaagatacc aaaagaaaaa ctccacatcg tgtatactaa
     1861 gacataagcc atctcaggcc aaaaagcttc agggttacgc ccgacccaac tagtaacaga
     1921 aggacataaa gtcagccaaa agagcaaaaa gatattcgac cagaccactc ggtaattaat
     1981 tcgttctgcc atctgaaata tacgatgatg gttcacccag atcaccgcaa caaatataaa
     2041 gctgatggta taagctaata atgtatttcg gatgacccat aaagaatgaa agctagatgt
     2101 attagggatc ttgatctcta atacaataac tctcaaaaca atggctacca ctccatcagt
     2161 aaatgcttct aatctcgact ttgtcacgat gattcctcct cagatgattc agcgctttta
     2221 ttttatcact tacgttatta aataaccatc gttttatata gggaattttc tgaaaattgt
     2281 tgcatatttt tcgaaatttt gttactttta aaaaaaccgt aaaggagtta tgtatgacaa
     2341 aaaaattatc atttaaagac tatcttttta taggctccat gcttttcggt ctattttttg
     2401 gtgctggaaa tcttatcttt cccgttcatt tgggtcaaga agcaggcgct gctacctttt
     2461 gggcgaatct aggtttcttg gttaccggta tcggtcttcc cttcttaggg gtgattgcca
     2521 ttggtgtatc gaaaagctca ggtgtatatg aattagcaaa acggataaat caaacatatg
     2581 cgatggtttt taccatcttg ctttacttag ttatcggacc gttttttgct ttacctcgcc
     2641 ttgcaaccac atctttcgag attggtttag caccatttat cgatcctagc agacagacgc
     2701 tatatctagc aattttcagt attgtatttt ttgtgctggc ttggtggttt tcaagaaaac
     2761 cgacaaagat attagattat gttggaaagt tcctgaatcc tgcatttttg gttttattag
     2821 gtgctttgct tctccttgct tttttgaatc cactaggttc tgtaaatcaa gcgcctattc
     2881 agccaaatta tcaagagcat gcttttttca cagggtttac tcaaggatat aacacattag
     2941 atgcgcttgc tgctttagca tttgggatca tcattgtcac aacaatccaa aacatgggtg
     3001 taacaaaacc tgctgaaatc gctaaagaca cgatcaaatc tggtgcgatc agcattatat
     3061 tgatgggaat catttatact ttgctcgctt atttaggtgc tatgagctta ggtagctttg
     3121 ctctaagtga aaatggcggg atcacgctgg ctcagattgc tgatcattat ttaggtactt
     3181 atggcagtat cttattagca tttatcgtta tattagcttg cttgaagacc ggtattggtt
     3241 tgattacagc ttttgcagaa acattcacag atttgtttcc gcaaagaaat tacgcattct
     3301 ttgttgcact tgctagtatc cttccttgtt tagcggcaaa cgtaggcttg acgaatatca
     3361 ttcaattttc gttgcctgtt ttgatgttca tctatccatt agcaatgaca ctgattttac
     3421 tagtgttagt tggtcctttg tttaagcagc gtacggctgt ttatcgaatg actacttatt
     3481 ttacattgat tgcttcgatt tttgatgggt tgaacgcttg cccagaaact atcaaacaaa
     3541 cacctattgt tcaaaatctt ttatatgttg cggaaagcta cttgccgttt ttcaaattgg
     3601 ggatggggtg gatcgtacca gcagttatcg gttttgttat cggactgatt tggagtttcg
     3661 ctaagaaaga agaagtagca gattgataaa agaggttgtg aaagagacgt tcagccttga
     3721 gcaataaaaa gtaattttga aaaatggctt ctcacatttt tgcataaatt tgacttaata
     3781 ccgagaaact gacttttgaa caccgtttat tgagaggtcg tgaaaaagcc gcttagtttc
     3841 aagtattaag aaatattttg tgaaaatggc ttctcacatt tttgcataaa tttgacttaa
     3901 taccgagaaa ctggcttttg aacaccgttt attgagcgtc tataaactga cctgagtatt
     3961 agagaaacaa aacggcaaag tagctccata tactttgccg ttttgttttg aactaatacc
     4021 gaagagaagc tgatcaaaca acatttcttt tataatatag attttagaca tatatatgat
     4081 ataaaaatag ttttcgcaaa a
//
LOCUS       DACGMI010000121         4048 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.127, whole genome shotgun sequence.
ACCESSION   DACGMI010000121 DACGMI010000000
VERSION     DACGMI010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.127"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            236..1111
                     /locus_tag="IXT46_002899"
     CDS             236..1111
                     /locus_tag="IXT46_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4948764.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            1215..1979
                     /locus_tag="IXT46_002900"
     CDS             1215..1979
                     /locus_tag="IXT46_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAQ4948765.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            1996..3408
                     /locus_tag="IXT46_002901"
     CDS             1996..3408
                     /locus_tag="IXT46_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4948766.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            3425..>4048
                     /locus_tag="IXT46_002902"
     CDS             3425..>4048
                     /locus_tag="IXT46_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAQ4948767.1"
                     /translation="MKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDEER
                     NMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKIPL
                     KHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVRRK
                     YPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIY"
BASE COUNT         1331 a          591 c          854 g         1272 t
ORIGIN      
        1 tttcttatag agagttgcta tatttttttt gtttttatgt aattacctcc aaatcaattc
       61 gatacaagta ttatcataaa acgagtaaaa aagatattga taacgctttt attatgtgtt
      121 aaactatttt tgtaaattat gtagggtgct actattcaat taggcacgac ctaagaaagg
      181 gttctttctt aggtcgtttt ttgtctttaa aaattgtttg gagacaaaaa tatgtatgaa
      241 ggagtctgca agttgttttg ttttatcata tagaggaggt gaattaacgg tgtatgtgat
      301 gaaaaagctg aatcataatg ctgtattgat cgatgacgat ggaatagaaa aaattgcgat
      361 ggggaaaggg attggctttt ctgctaaagt gagtaagcca tttgatgttg aggatgctga
      421 caaattattt gtattagatt ctaaagaaaa gatcaaacga ttcagtgaga tagtctcgca
      481 gattccaatc gaatttatgg attttgcgga agaagtgatt gaactgataa cagctaggat
      541 ctcctctcca ttagattcaa atatctatat tacattgaca gatcatattt attttgctat
      601 tcaacgaaaa agagaagata gagatgtcac agcaattatg ttgccagaaa tgagattcct
      661 ttatccaaat gaatatgata tagcagtaga agtggtcgag cgaatcaatc atcgatatca
      721 aaccgagtta gggtcaaatg aagtaggatt catcactatg catatcatta atgctgagct
      781 aggagagcct aatagtttaa agagcttaaa aatagtagaa atgacgacca cgattttgtc
      841 ccatctagaa aaatcctatt caaacgttta tgataaagaa tcactgactt atcatcgctt
      901 aatggttcat atcaaattcc tggttaaacg cttgatttat caggaagaaa cgccagtaga
      961 aaatattggt ttttttactg aaacatttaa acatagcaaa gcgtattgta cagcactaaa
     1021 gattaaagat atcatcgaac agcaatttca acttgccatt caagaaaatg aaatcatcta
     1081 tttggcaatt catctagcaa gaatctatta aaataagggc gtaactatct ataggcgcaa
     1141 ccaaatgaca catagtaaat ggactatgat tatttggttg cgcctatttt agtagaaaaa
     1201 agaaggagaa tgaaatggga aaagtgattt ttaattcgga tgattttggc tatagccatg
     1261 gtgtgaatta tgggattatg gatgcttatc agcgaggaat tttgacatca actacattga
     1321 tggcaaatat gccgggtttc gagcatgctg tgaaactaag aaaggaaatg cctaggctag
     1381 gtgtaggagt ccatttaaca ttgacgtgtg gcaaaccact cctcaaaact gtcgatactc
     1441 ttatcgaaag cggagagttc agatccttat cttattatca gcatccattt aacattgaca
     1501 aagatcaact gtatcaggaa tggaatgctc agattcaaaa aatttatcat gcggggatca
     1561 taccaactca tttagacagt catcatcata ctcatacttt ggatgaaaat caggaggtag
     1621 ttgttacatt agcaaaaaaa tatgatttgc cggttcggag caactttgaa cgaaaagatg
     1681 aagttcgtca tgtcgattat tttgagcctt gtttcgatgt cgtaggagaa actgatgaaa
     1741 aaaaacgaca aatcaatacg agtgtggaag aatatttggc aagtttactc atgatattga
     1801 gagaagataa aacgatcgaa gtcatgtgtc acgcagcgta tttggatcag gaattgttaa
     1861 atggttcaag ttttgtgtat cctcgtaccc accaagtcga atttttaatt cattcagcat
     1921 ttgctcaaaa agtgaaaaat gatcctttga ttgagttagt aacatatgag gatatttaat
     1981 agaggaggaa taaaaatgaa tgttaaatca aatgtgcaga agcttggaag agcgatgcta
     2041 cttccagttg cagcgatgcc attagcggga ttgatcatgc gtttatcagc tgacgatatg
     2101 ctgaacatcc cagtaattgg tgcagctgga aatgccgttt ttggaaactt ggatatctta
     2161 tttgctatag gagttgcaat cggttttgtc aaaaataagg acaaaggaat acctgcactt
     2221 actggttttt tagcgattgc taccttgaaa aaaggcttag aaattatgga cccagaagtg
     2281 aatatgggga tttttggtgg aattatttcc ggtttagtag cggcatggac gtataatcgc
     2341 tttaaagaac aaaaattacc agtagttttt tcttattttg cgggcgaaaa attcccattg
     2401 actatggtga tgattctaca aacaatcgca gctgtttttt tgggctttat ctggccgctc
     2461 atccaaattg ggattgataa ttttgcaaaa ctgctcgttg atatgggagc attaggtgtg
     2521 gggatattta tgtttttgaa tcgtttgctg atcccctttg gactgcacca tgtgttgaat
     2581 acgtatattt attacgattt aggaagctat acatctccta gcaaggaagt tttcagagga
     2641 gagatgacac gctttatcaa cggagatcct caggctggac tgtttttatc aggttttttt
     2701 gtagtaatga tgtttggtat accagctata tgtctagcta tctataaagc agcttataaa
     2761 gaaaataaag agatggtcaa aggaatcatg ggaagcggtg caggaacttc atttattgca
     2821 aatatcactg agcctgttga atttagtttc atgtttcttt ctcctatgtt gtacgtgatc
     2881 catgcacttt ttgccggttt agcagggatt gtctgttact tattcaatat acgaattggt
     2941 tttacattcg gagcatgtat tgttgattat ctcatcaatt ttcgaatcgc taccaatgct
     3001 attttgattc ttccaatcgg aattttcttt tttgccttgt attacgttac tttttattat
     3061 ttgatcaata agagaaacat tcagacatta ggacgtgaag ctaaggcaga gtttggcaat
     3121 gaagtaacct tagaagaaac agagttaggg ttagcaagta aaaattatga atatatggca
     3181 acaaaaatgc tacaagcgtt tggaggaaaa gccaatatcc tggatgtcta tagttgtaat
     3241 acacgcctac gggtagaggt agtggatccc accatggtcg aggaacagcg aatcaagcaa
     3301 ttagggataa gcgggatcat taaaccaact gaaaaaaatt atcaaattat catcggctta
     3361 gaagtgactt atgttatggc agaattcaat aaattattag aagaatagaa aggaaaagat
     3421 gatgatgaaa aaacagatta tcactatagc tggaggcggg agtacgtata caccaggaat
     3481 cgttcaagcc attttgaaca atgaaaaacg gttgccatta tctgaaatac gtttatatga
     3541 tattgatgaa gaaagaaata tggatatgta cttgattgtt aaatttatgc tgaaaagaaa
     3601 aggtttttca aatattcgca ttcgtgcaac ggatgatcca aagcttgctt ttacaggatg
     3661 cgattttgtt ttctcacaaa ttcgtgttgg aggattggag atgcgagaaa aggacgaaaa
     3721 gattccactt aaacatggat tagtaggaca agaaacgtgt ggactcggag gatttgctta
     3781 tgggatgcgc tcaatcaaag gtttattgga aattgtcgat catatacaag actatgcccc
     3841 caaagcatgg attttgaatt atacaaatcc agagtcgatc gtttctgaag ctgttcgtcg
     3901 taaatatccg aatgtaaaaa tgattaatgc ctgtgatatg actatttcaa ttgaagaaac
     3961 gattgcagtg aattacggtt atgatcgtaa gaattggatc gttacgtatt atggtttaaa
     4021 ccactttggc tggtatacat cgatttat
//
LOCUS       DACGMI010000122         3894 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.128, whole genome shotgun sequence.
ACCESSION   DACGMI010000122 DACGMI010000000
VERSION     DACGMI010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.128"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..354)
                     /locus_tag="IXT46_002903"
     CDS             complement(<1..354)
                     /locus_tag="IXT46_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948768.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRTF"
     gene            complement(614..1162)
                     /locus_tag="IXT46_002904"
     CDS             complement(614..1162)
                     /locus_tag="IXT46_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948769.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1163..2020)
                     /locus_tag="IXT46_002905"
     CDS             complement(1163..2020)
                     /locus_tag="IXT46_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4948770.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2306..2592)
                     /locus_tag="IXT46_002906"
                     /pseudo
     CDS             complement(2306..2592)
                     /locus_tag="IXT46_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2582..2911)
                     /locus_tag="IXT46_002907"
     CDS             complement(2582..2911)
                     /locus_tag="IXT46_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4948771.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2988..3260)
                     /locus_tag="IXT46_002908"
     CDS             complement(2988..3260)
                     /locus_tag="IXT46_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAQ4948772.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3260..3523)
                     /locus_tag="IXT46_002909"
     CDS             complement(3260..3523)
                     /locus_tag="IXT46_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4948773.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            3757..>3894
                     /locus_tag="IXT46_002910"
     CDS             3757..>3894
                     /locus_tag="IXT46_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAQ4948774.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
BASE COUNT         1166 a          784 c          498 g         1446 t
ORIGIN      
        1 aaatgttctt actgcctctt ccacactaat ttcttcgttc aatttcacta ataatacttg
       61 atctcgctta ttataatcgc tttcatttat cctaagagtc aaatcttttt ccaccataac
      121 ttttacaccc aataaatttt gcggtttatt tttctctgtt gaaattcttt gtgtagcctt
      181 taaactgaca attagctcat tgggtacata ctctatttga gagtcatcta attggctcat
      241 aatcctttct ttttggttag tatctgcagt tacttgttta gtatgagcca tgaacccaaa
      301 catactcacc ccaacaacca atcctaaata tattttcttt ttaaactttt tcatctacat
      361 ctcctcctaa tagttttatt ttagagttag ctctattact tatttactaa ctcaacaaca
      421 gattatcata cacttgttaa tgaaatcaca atatctcatt aaaacacacc ctaaaatcat
      481 aaccgttcct atgctcattt tttggatttt ttaatcacgt aaccagaaaa ataaatcccc
      541 tctatttcac gcaaatcaaa gaagaactaa gtaactaccg tttaaaggta gttacttagt
      601 tcttctttga ttattatcta actttattat tcattcccca ccctttgcgc agtgagtctt
      661 cggtatcttg ttttatctga ctggtagttc ttattatttc tccacgatca tctaattctg
      721 gaacaattgg atatttttct ctgaacaagt ctagttcttt caccacgtca ttaaacaaat
      781 cttgcttatc ttcttgcgta agattctgtt taatatactc atctaaagct tttctaagca
      841 attcatctct tgtcatatta gtctcatact tttctactaa aactctggaa gtcgcattta
      901 acaaagtcga cagttttaaa ggatgcttgg tggaataaac cttatcaaac tttctgattg
      961 gtgcgccaac tttttttgtt cttcctctac tctgtctttc aacattggag gaagttttta
     1021 tttcttgaac ttggtgcact tctaattgct tattttcaga tggtgtaatt gcttgctgct
     1081 ttttctttgc ttctgcttct ttttttattt tggcgagtcc tttgttgttc ccaaaaatat
     1141 caagtccttt gatgtcagcc aattactcca cctccgcata ccaattctcg tgttcttcca
     1201 attctttcaa aatactgata aataattcgt ggcttttgcg atcccattgt tttaagagac
     1261 ctttctttgt cttctccatc gtaatacctg atccgtcgta tcgttttaag cgcgcatttt
     1321 tgagtacaac atttttaatc aaatgttccc cataaatctc ttgggcttgt ttatacattt
     1381 cctgatctac tgcgtcaccg ctttccaaca tgaaaggaat aacaccagca acatataaat
     1441 ttgtatcaaa ttctttcaca aaaaagtcca tatactcaag atattgcatc gcatttctca
     1501 tcgattttac ttgggtctgt aagacgacga ttgcccaatc cgcaatgtac atcgcggatt
     1561 tactatatac agaaatagaa ggtgggacat ctaaatagat gacgtcaaac tcatcaaata
     1621 atggttctag cttttctttc atatatttga attgggataa tgaatcatta tattggtctt
     1681 tgatccaatc atcatacatt tcaaaggaca tgtctgctgg aagtatatag aggttattga
     1741 ttactttata gacagcctct ttaggtggaa gattgtttat caacacgtca gtcacagtat
     1801 tttcgtaaac aatcggttca ccttctccgc ctccttcttc gttagtgaag ttcatatgcg
     1861 ttaagttcat cacatcagaa gtatttcctt gcatatccaa gtcaattatc aaggttcttt
     1921 ttccttcatt aactgctgat tcaaacccta acatttgcgc gcacgtactt ttacctacgc
     1981 cacctttaaa attaccgatt acatatttct tcgctaccac gttcctacct cttttctttt
     2041 agcaatattc atttgatact attataacat atttattttt agttactacc aaaaaaaaga
     2101 tatatatgta ctaccttata attaataagt aaaaggtagt acataaataa ggaaaagctg
     2161 aaatatattg atttatagct ttcctcaaag taatgacgtt atttaattta tcgagaagca
     2221 gagaatactc gcgactttag tcatgtagac gaatcagatt ttcgataaaa aagaagccgt
     2281 ccttcttaag aacgacaaca aatcactaga ttaatttttt caactgttca taaaagtttt
     2341 catgcgttcc acataacaat actggaataa ccttgttttc tataatctcg taagctactc
     2401 tatatgttgt gcccgcatat ttgaacccac tagaccaaat acctgataaa tccccagttt
     2461 tttgttcacc cttatatgga tcaatcgcaa tttcatcata aattaaattc aaaaattttt
     2521 ctttcaatgg cttctctttt agctttttaa atacttaatg acatgttttg aaggaacgat
     2581 ttcataagcc aatttctgtt gccaactcct ctttagtcat tactttagaa ttagtaagtg
     2641 tatcttcagc aatatctcta aaggaagaat gcattttgtt ttttctattc ttaaattcta
     2701 caagaatctc atctttatcg tagccttctg caattatatc agacaaaata tcttcgctaa
     2761 aatcataaaa ttctttttgt ggttcaacaa attcataaag aataccattc tctaccaact
     2821 ttgcttcaac ttcgactcca ttaggaacat taaaatcttt aggtactgtc aacatgattg
     2881 aattgccttg ttttcttgtt tttgtaatca tttaaatccc tcatttctaa cagtatgtaa
     2941 ttacttagta aatacattat accacgagat aatgtattta caagtaatta ctgtgactcg
     3001 taatgcgtcc ttgctgaata aatttcaacc acgtgttcat cttcatctac cttataaaca
     3061 acccggtgtt gtctattcaa tcttctagaa tacctacctt catgtgtagg ttttaacttc
     3121 tcaaatgatt gggtagggag atagggatct tcctttaaag tctgaataac cttctcaaat
     3181 tgaggtttca aattagactg tttgattttc tttaaatcag ctttagccga gtttttaatc
     3241 atcacagaat agttattcat tataagttat cccaatcaat ttcatcaaca ttagtaaatc
     3301 cactatcatc tttttctcgc ttacgaacaa cacccaaagt gcctatttgc tcaagtaata
     3361 gcgtttcttt gattgctttc caatcatcca aaccaataag caccgcatta ttttcactgc
     3421 gctcactaat gatttcaatt tccgtatgat tctcatttac atctttcaac aacttataaa
     3481 aatttttccg tgctgagcta ggatttaaga ctgtttttgc catatctact ccccctctaa
     3541 tttatatctc cattctaacg tacttaatta agtacgtaaa ttcgattgtt ttgtttaaat
     3601 tggagtacca aaacagcatt gtaaagtgtt atccgtttcc tttatacccg tggtgctagt
     3661 taattttttc ctagaggaaa atgtctaaac atgttggtaa atcaacaaaa aaacgcatag
     3721 agtagtctca aaactcccaa gaaatgagga ctacatatgc gttcatcaaa atatactgaa
     3781 cattatacag atacttttat aacattcaag gaaattatga gaactgtttc taacatatac
     3841 cacaattgtg taccagataa gattaaaaac cgaagaaata ctgatcaact gaag
//
LOCUS       DACGMI010000123         3638 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.131, whole genome shotgun sequence.
ACCESSION   DACGMI010000123 DACGMI010000000
VERSION     DACGMI010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.131"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..330
                     /locus_tag="IXT46_002911"
     CDS             <1..330
                     /locus_tag="IXT46_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4948775.1"
                     /translation="DFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLTNIENKGQQP
                     SFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVTIGKVIQAIY
                     GEKCKFN"
     gene            complement(844..1011)
                     /locus_tag="IXT46_002912"
     CDS             complement(844..1011)
                     /locus_tag="IXT46_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4948776.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITV
                     ITEPDAKTQSR"
     gene            complement(1099..3039)
                     /gene="tet(S)"
                     /locus_tag="IXT46_002913"
     CDS             complement(1099..3039)
                     /gene="tet(S)"
                     /locus_tag="IXT46_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HAQ4948777.1"
                     /translation="MEEIKLKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSG
                     TTKTDTMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAIL
                     LISAKDGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIK
                     QTVNLNLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSL
                     YPVYHGSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLY
                     SGTLHLRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGD
                     KKRLPHREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIV
                     LSFLGEVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASI
                     GLSVTPLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKY
                     GLYYSPVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKY
                     CANILNTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAF
                     QPRRPNNRIDKVRHMFNKINLH"
     gene            complement(3040..3126)
                     /locus_tag="IXT46_002914"
                     /pseudo
     CDS             complement(3040..3126)
                     /locus_tag="IXT46_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011058339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance protein"
BASE COUNT         1169 a          606 c          563 g         1300 t
ORIGIN      
        1 gatttcaaac cattgggtct tgcgattaaa gaagcccgtc ttagtaaagg attgactcgt
       61 gagcaggtag gatcaatgat ccagattgcg ccacgctatt tgacgaacat tgaaaataaa
      121 ggacaacagc caagttttca tgttgtatat gatttagtga ctttgctaaa tatttctttg
      181 gatggattta ttttagggga agaaaacagt cataaaagct ccaaacgtct tcaagtagaa
      241 gcacagttgg attgtctgga tgaagatgaa ttagtgacga ttgggaaagt gattcaagca
      301 atttacggag aaaaatgtaa atttaactag ttcaataata cacaatggat taattaatac
      361 tatcaggaaa gattgattac aaagatgtaa tgaatttttt ctgatttttg ttaatcataa
      421 atagaaaatg aatttatctt tgttacactt aggaactaga gcgaatgata aatagttctt
      481 tggttactct tatcgctgca aagtacagtt cattttttgt tgttgggaaa attttctgga
      541 tttattgcat atcacttcat ccgactaaaa atttttgatt cccatagcga agttcgtttt
      601 tgttccttag gaaaaacttg actgatatac tagttttgaa atgacgagta actctgtact
      661 tcatcaataa tcaagtattg aattttaatt gtatactttt tatgcttgag ggatgtctac
      721 tgtaatacag ctactgcaaa aaaaatcagt acacttattt tcttataaag gatatcaaga
      781 actaagctca atggtatgca tagaaaagaa aaagccgata aaatgagatt ttgatatctc
      841 gaattatcgg ctctgcgtct ttgcgtctgg ctctgtaatt acagttattc taaacttcgt
      901 tatttcaatt aaaatttctt gtctgcattt aggacaaaat agagggaaat tttttaattc
      961 agtatcttcc ctcattttta aacgggtctt attgccacat atagggcaca gtatccacct
     1021 agtatttaca atatctatat cctcctgttc taattaacaa ctcaatattc attttaaaaa
     1081 tttctcttta gttcactatc aatgtaagtt gattttatta aacatatgcc ttactttgtc
     1141 tattctatta tttggacgac gtggttggaa agcagactta atgttagtaa cctgataacc
     1201 ttttaactct gttaaacaga cactgcgtcc atttgtaaag aaagttaaac tgtttcgata
     1261 ctcttgaata caacgggctg gaatttcacc aatgagaatg acctcgttac cttttaactt
     1321 agtatttaaa atatttgcac aatatttgga agcatcatta tatgctctcg aaagatattc
     1381 ttgtggtaca taaatttcga agctaagata tggctctaat aactctgtac cactctttct
     1441 aaaagcctgc tctagtacaa taggcgcaag cattcggaaa tctgctggcg tactgacagg
     1501 gctgtaatat agaccatact taaaacagat cttacagtct gttaatttcc aaccgtacaa
     1561 tccttgttca cacccatagc gtataccttc cataactgca ttttgaaatg attgatttaa
     1621 ataacctaga gaaaccaggc tctcatactg aatgccacta cccaaaggaa gtggtgttac
     1681 agataaacca atagaagccc agaaaggatt tggaggtact tcgatatcaa tggtaaattc
     1741 agattttttt aatggtcttt ccatataaat gacagttggt tttcttgttt ctatctcaat
     1801 atgatatttt tcttgaatca gagtacaagt tacctccatt tggacctcac ctaaaaaaga
     1861 tagcacaatt tcgtgagtta ctgtatctac ataatattgt agaaggggat cactatcgga
     1921 tatttcaaaa agtgcatcta gtaacttttc tctttgtact gatttacatg gttcaattgt
     1981 tgtttgtaac ataggaagag gattctcaag aatttctcta tgtggtaatc tttttttatc
     2041 tccaagtacg ttatttagtt ttaaaagctc attttttaaa ataataatct caccaggctc
     2101 tgccttatct atctggcgta attctccatt tattgaagta tacatttctg taacttttat
     2161 tttttccttt tctgatatat tgactgagtc tcgcaaatgt agcgttccac tataaagacg
     2221 tacatagaca agccgttgac catcatctga atattctact ttaaaaacat ttccacaaag
     2281 tttatctgaa ttgagttgtg tgggtgaaaa taatttgcta gtaattacct ctataagttg
     2341 tttaattcca atattattct ttgcacttcc gtgataaaca ggatataagg agcaactttg
     2401 aattctttcg ttttcctcct tttcaagttc tgcaatattc aatgttttcc caatggtata
     2461 tttttctaat aaataatcat ttcccacaat tactgtctcc cattgttctg gttcagtata
     2521 atctattaca taaggtttca aatttagatt cacagtctgc ttaattatga tgtcgtcaga
     2581 aagtttgtcc ttaatatctt gataaacatc tggcaaattt attccatttt gatcaatttt
     2641 gttaataaaa aatattatag gtatgttcat ctttctaagt gcatggaata gtatacgagt
     2701 ttgtgactgt actccatctt ttgcagagat tagcaaaata gctccatcca aaacagataa
     2761 tgaacggtat acatctgcca aaaaatccat gtgtccagga gtatctacaa tatttacttt
     2821 aacattttcc cgttgaaaag atgttattgc ggtctgaata gtaatacctc tctggcgttc
     2881 caaaaacata gtatccgttt tcgttgtacc gctatctaca cttcctaact ctttaattgc
     2941 tccgctactg tatagtaagc tttctgtcaa agtagttttt cctgcatcaa catgtgctaa
     3001 gataccgata ttaataattt tcaattttat ttcctccatt caaaagctca aaaagcagaa
     3061 aaaatcccag tgataaatac tcttatcact gggattttaa tacaaaaata gctgtatact
     3121 acacactgat agccacagat gctttatgat aaaatgataa aagtattctt aaactgggca
     3181 caaaaaacca gtccttattt taaataagga tgcttaatta attattcccg ctatctaatt
     3241 gacagtttat ttaagaatac cttgccgcat ttttattatc tccttttgaa tgttatctta
     3301 attctatcat atgatagaat gcttgtaaag ccaaccatat tttttgaacg aaagggaaat
     3361 taatgagaaa ttaatggaag ttagtgtagt agttgaagat aactcttcag aatggctatc
     3421 aaaattcagc gatttaataa cgatttacaa gttcataagg gattctttat tcatccagct
     3481 attatattac ttttcaggtc aataggacaa ctgtccacaa cctttctaca aatatattac
     3541 gtataatttt tgaaatatat actgcttaac aaaatatttt gcagtggttc caatagtttt
     3601 gaattgttaa tattaagttt gacttggaaa atatcatt
//
LOCUS       DACGMI010000124         3480 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.132, whole genome shotgun sequence.
ACCESSION   DACGMI010000124 DACGMI010000000
VERSION     DACGMI010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.132"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..778
                     /locus_tag="IXT46_002915"
     CDS             <1..778
                     /locus_tag="IXT46_002915"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAQ4948778.1"
                     /translation="CKKNNRIPVVEIKATGGYTKEQLQLIKTISDGIGMTEKTIFISF
                     NYDMLVLMREIFPFNELQWVYQGTINTDVITKLKTLGLPCGLDINENNASLTKDNVNL
                     LHANRLKIGAWTVGYNSFEKMKDLGIDYITTNSPSGYLKYAELSLLNGFTPTNDNGQV
                     PQFAAELEGGYVFLSFNVKDGTNNNQLTEIAKLPDWAIPHEKQYNQCMIRTSSGVSLA
                     TFDTQGWKHSTGVTEGTITIGLGWSSRTTWAAGQCIYKID"
     gene            842..1084
                     /locus_tag="IXT46_002916"
     CDS             842..1084
                     /locus_tag="IXT46_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAQ4948779.1"
                     /translation="MKDEAIQDVVERLVRIETKLDNYESLREKAESAKDRADQAYSIA
                     LNNAEDIKEMKANNKWSWGYMIGLGITIIGYFLTKL"
     gene            1100..1297
                     /locus_tag="IXT46_002917"
     CDS             1100..1297
                     /locus_tag="IXT46_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAQ4948780.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            1308..2585
                     /locus_tag="IXT46_002918"
     CDS             1308..2585
                     /locus_tag="IXT46_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4948781.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAAKNDQGVDWSIYQGENGRF
                     GYAHDKFAIAQIGGYNGAGLYDQWTYSTQVASAIAQGKRAHTYIWWDVWGSPAIAKQT
                     MDYFLPKIQTPKGSIVAIDFEGGASSNKQANTDAILYGMRRIKAAGYTPMLYSGKPFL
                     LANAYYQQVIKEFPDSLWISAYPDYNVTPTPNWNIFPSLDGIGIYQFTSTYITGGLDG
                     NIDLTGITDNGYTGSDKPATDTPATDAGEEANDTPKSEIKVGDTVKVNFSAKNWATGE
                     AIPQWVKGESYKVQQVNGNKVLLANILSWIDKSNVEILPDSTTVPDKPSAGIQTHVVQ
                     YGETLSSIATKYGTTYQALASLNGLSNPNMIYAGQVLKTNGTANVTRTYTVRSGDNLS
                     SIASKLGTTYQALAQRNGLSNPNLIYPGQVLSY"
     gene            2837..3223
                     /locus_tag="IXT46_002919"
     CDS             2837..3223
                     /locus_tag="IXT46_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948782.1"
                     /translation="MLLKFDEYPDSCPPGNAIKFEGTFYRLCKGNPFCKEDFLTHFEA
                     GFNFPSSKLCEAMALSFYDSYAHAESLKNQYRKKFKDHSIIPVKIIEKYGVGILEEKK
                     GHLNLWENRNVDIFSDLIKEGGDKDG"
     gene            3216..>3480
                     /locus_tag="IXT46_002920"
     CDS             3216..>3480
                     /locus_tag="IXT46_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948783.1"
                     /translation="MDNQFFSSLEYIFIFDYYDSPLFFISQSSENNRYYLFYSIDDDA
                     YFFSELSASDINYLFMNPNGYDILHYLKDKSKLKFVLISKKSFN"
BASE COUNT         1185 a          524 c          682 g         1089 t
ORIGIN      
        1 atgtaaaaaa aataatagaa taccagttgt tgaaataaaa gctactggtg gatatacaaa
       61 agagcaactt caattaatta aaactatttc tgatggaatt gggatgactg aaaaaactat
      121 atttatcagt tttaactacg atatgttagt tttaatgcga gagatatttc cttttaacga
      181 attacagtgg gtatatcaag gtacaattaa tacagatgtt attacaaaat taaaaacgct
      241 cggtttacct tgcggtttag atataaatga aaataatgcg tctctaacta aagataatgt
      301 aaacttgcta catgctaatc gcttgaaaat tggcgcgtgg actgttggat ataattcttt
      361 tgaaaagatg aaagacttag gaatagatta tatcactacg aatagtccat ctggttactt
      421 aaaatatgcc gaattaagtt tgcttaacgg ttttacacct actaatgata atggccaagt
      481 cccacagttt gcagcagagt tagaaggagg atatgttttt ctaagcttca atgtaaaaga
      541 tggaacaaat aataatcaat taacagaaat tgccaaacta cctgattggg ctatccctca
      601 tgaaaaacaa tataatcagt gtatgatacg gacgtctagc ggtgtatcac tagctacttt
      661 tgatacgcag ggatggaaac attctacggg tgtaactgaa ggtacaatta ctattggctt
      721 aggctggtct tcgagaacta cctgggccgc aggtcaatgt atttataaaa tagattaatt
      781 ttgctaccaa cacgctcaat agagggtgtt ttttattttg caatgaaagg aggctagttg
      841 gttgaaagat gaagcaatac aagacgtggt agaacgttta gtgcgtattg aaacgaaact
      901 ggataattac gaatcattac gcgaaaaagc ggaaagtgca aaagatagag cggatcaggc
      961 atattctatt gcgcttaata atgcagaaga tatcaaagaa atgaaagcca ataataaatg
     1021 gtcgtggggt tacatgattg gtttaggcat tacgatcatt ggctatttct tgactaaatt
     1081 gtaaaggagt taagaagaaa tgattttacc cgataagtat tatcaagtca ttaaatggac
     1141 ggttttaaca gttttaccag ctgcatctgt tttagtagcc acgttaggaa aagcgtatgg
     1201 atggaatgga acagatatga cagtactcac tatcaatgca gtagcaacat ttttaggcgt
     1261 tatcactggt gtgtcggctt ataatttgaa aaaataggag gaaacaaatg aaaaagaaaa
     1321 ttactattac tgcgatgagc ctattaacgg ctcttttttt attgccaatt aatggatttg
     1381 ctgcaaaaaa tgatcagggt gtggattggt cgatttatca aggggagaac ggaagatttg
     1441 ggtacgctca tgataaattt gctattgcac aaattggtgg ttataacgga gctggtttat
     1501 atgaccaatg gacctactcc acgcaagttg cttctgcaat tgcgcaaggc aaacgagcgc
     1561 atacctatat ttggtgggat gtgtggggtt ccccagcaat tgctaaacaa acgatggatt
     1621 atttcttgcc aaagattcaa acgcctaaag gttcaattgt agcgattgat ttcgagggtg
     1681 gggcatcttc taataagcaa gctaatacgg atgccattct ttatggtatg cggcgaatta
     1741 aagcagcagg ctatactcca atgctttatt caggaaagcc gtttttatta gctaatgctt
     1801 attatcagca agtaatcaaa gagtttccag attcgctatg gatctctgct tatcctgatt
     1861 ataatgtaac gccaactcct aactggaata tttttccatc gctggacggt atcggtatct
     1921 atcaatttac ctcaacttat attactggtg gattagatgg taatatcgat ttaactggta
     1981 ttacagacaa tggttataca ggttcagaca aaccagcaac agacactcca gcaacggatg
     2041 caggggaaga agctaatgat acgccaaaat cagaaattaa agtgggcgac actgtgaaag
     2101 tgaatttctc agcgaaaaac tgggcaactg gagaagcgat cccacaatgg gtaaaaggag
     2161 aaagctacaa ggttcaacag gtaaatggca ataaagtttt acttgcaaat attttatctt
     2221 ggattgataa atcaaatgta gaaatcttgc cagattctac aactgttccg gataaaccat
     2281 cagctggtat ccaaactcat gtcgttcaat atggagaaac actatcttca attgctacaa
     2341 aatatggaac aacgtatcaa gcacttgctt cgttaaatgg actaagcaat ccgaatatga
     2401 tctatgctgg acaagttcta aaaacgaacg gaacagcaaa tgttactaga acatacactg
     2461 ttcgatcagg cgataattta tcatcaatcg catctaagtt aggcacaacg tatcaagcgc
     2521 tggcacagcg caatggatta tcaaatccta acttgattta tccaggtcaa gtactatcat
     2581 attaaaaaaa gcccctcgat gagggacggt acttgaaatc atatataaca tttttgttac
     2641 aaaattaatg ttatgaatgt cacaaagtgt tgttttaata tcataaacgt ttaacttgaa
     2701 cttatgttcc ctgtatgcta aagtaatttc ataatcctca aagattatat ctgctaagaa
     2761 gcccagaggc tattgtcttt agggctttct tttggtttaa ttgtgttagc agatataaaa
     2821 cgaaaagtgg ggatatatat tgttaaaatt tgatgaatat cctgatagtt gccctcctgg
     2881 aaatgctatc aagtttgaag gaacatttta tagactatgt aaaggtaacc ctttttgcaa
     2941 agaagatttt ctaacacatt ttgaagcggg ttttaatttt ccgagtagta aattatgtga
     3001 agctatggct ctatcttttt atgatagcta tgctcatgca gagtctctta aaaatcaata
     3061 tagaaaaaag tttaaagatc attcaattat acccgttaaa ataattgaaa agtatggagt
     3121 tggtatttta gaagaaaaaa aaggtcattt gaatctttgg gagaacagga atgtagatat
     3181 tttttctgat ttgataaagg aaggtggaga taaagatgga taatcaattt ttttctagtt
     3241 tggaatatat ttttattttt gattattatg attctccttt gttttttatt tctcaaagtt
     3301 cagaaaataa tagatactat ttattttact caatagatga tgatgcttat ttttttagcg
     3361 agttatctgc ttctgacatt aattatttat ttatgaatcc gaatggttat gacattcttc
     3421 attaccttaa agataaatca aaactgaaat ttgttttgat aagtaaaaaa tcttttaata
//
LOCUS       DACGMI010000125         3391 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.133, whole genome shotgun sequence.
ACCESSION   DACGMI010000125 DACGMI010000000
VERSION     DACGMI010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.133"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            647..964
                     /locus_tag="IXT46_002921"
     CDS             647..964
                     /locus_tag="IXT46_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAQ4948784.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="IXT46_002922"
     CDS             complement(1055..1420)
                     /locus_tag="IXT46_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948785.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="IXT46_002923"
     CDS             1628..2110
                     /locus_tag="IXT46_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948786.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /gene="pstS"
                     /locus_tag="IXT46_002924"
     CDS             2307..3197
                     /gene="pstS"
                     /locus_tag="IXT46_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAQ4948787.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1172 a          519 c          619 g         1081 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac t
//
LOCUS       DACGMI010000126         3334 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.134, whole genome shotgun sequence.
ACCESSION   DACGMI010000126 DACGMI010000000
VERSION     DACGMI010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.134"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..426)
                     /locus_tag="IXT46_002925"
     CDS             complement(<1..426)
                     /locus_tag="IXT46_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAQ4948788.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
     gene            complement(535..1566)
                     /locus_tag="IXT46_002926"
     CDS             complement(535..1566)
                     /locus_tag="IXT46_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4948789.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            2290..3276
                     /locus_tag="IXT46_002927"
     CDS             2290..3276
                     /locus_tag="IXT46_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAQ4948790.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         1136 a          527 c          620 g         1051 t
ORIGIN      
        1 aggaatctgt tttgattttg ttccatttga aatttctctc actcgctttt ttgtctcatc
       61 atcaaataaa atgaaagggt cttctaaacg atcgataaat acttccattg ttgttgttgg
      121 tagatgataa gaagtcatga caggcactgc accaaggtaa gacacagaaa cagctagaag
      181 gtatgtgtca aaagcggaac tcttataaat aataactttg tctccggatt tcactccaag
      241 atgagccaat tgataagccc gtttcaacac actttcgcag cattttttgt aagttgtttc
      301 aagtcctaat tctgggaaag ctgaaagtgg ctcatcaaag ataatcgggg tctcggaaaa
      361 gttagctgca gcttcttgaa aattcgtaaa taagttcaaa ggggaatacg ttatggtctc
      421 catcattcac actccattat cttttgttaa gtaatataca aattcaagat aatcgtaaca
      481 taatccttta tataataaca tagtttattg tgaaaaaaag atcatacatt tgttttatat
      541 ggaagaaacc cgaacgaatg ccgctaattc gtgataagaa aaatcaacca tcttttccca
      601 gatatcttga aaagaatggg atgagaggta tcgattacca cataaataat ttaccgcgtc
      661 agcatcatct aaatatagtt ctgcataata acgatatgtt tttctgcata gttctggcga
      721 tacgttttta tatactgtaa ttttgctcaa aatttggcga atagtccgag gagaaatttg
      781 ctgatcatgt gaggaacgaa aaacaaaaga attttcgtcc gtattttgtg ctgttaactt
      841 aaaatagttc tccagaaatg gcatcgcttc ttttggtatt ggtactttat tcagtctgtt
      901 ttcttttcta ttcagattaa gaatctgctt ggtcaaagat acatctttac gtttaagttc
      961 tactacttca tggatcttta atccgcaata cagaagaatg gcagtaattg caaggttcct
     1021 cggtctattc ttttcttcaa agctagcttc tctgcttgtt tgaaagcctt caatcgggat
     1081 aaacaaatgc tcaaaatctt tgaaaagttc tgcatcgata tatcgcggag ctgctttggt
     1141 tgtttccggt aaacttgtac ccaaaagaga aatctcttct tcaatcagtc ctttttgata
     1201 caaaaatcgt aaaaaatgat ttaatgaata ttgcttcctt gaaatcccgt aatagctatt
     1261 ttcaaacaat tgctccgttt cttggttcgc tgtagtttgg aacgaacgag tatgtcgata
     1321 gattttagct aagaaattct gataatcttg tttttctaaa tggataatca gctgatcatc
     1381 cacttcttca gaaaatactt ttctcaaata atcagtaaac agatgaaaat cttttgcgta
     1441 ttcatagcga ctgcctaatg aaagggaaga acgattttct tctaaaaact gttgaaagac
     1501 ggaagggagc aagtgtgtac gttgctttaa cttttcttgc agttgttttc tagttttgct
     1561 gtccattaca aattccctcc aatagtgttc attttctata ttttaccgca tttcatcaaa
     1621 tgaagataga cagtttgtct tgatcttagg aagcaaattt ttaactaagt actagctaaa
     1681 agatatgaag taagaagata catttttagt tattttatta gtgcagtcat tcttttgatc
     1741 ttttaattga tttatcctct ttttagctat gtggttactt catgagcaat gaaatggatt
     1801 tggttcgttc taatggcagg aggctctttc ttttatttcc gaaaaattag aaaacatttt
     1861 ttcagaatcg attggctctc catttattca ataatggttt gtctaacgat attgttggga
     1921 taattcttaa agaagtatta gaaatagttg gtacttcatt actttacatg aagatttatt
     1981 ctatggtagg agcaattata ttgagaatta atcctttttt atataagttg tttgcttatt
     2041 gatggattgg ataaattaaa ccatcacaac gagtggaaat tatatgaaat ttttcataaa
     2101 aattcatata gaaacaaatg acattttatt agaatatgac tttcattaac ataaatgttt
     2161 tcaaatttca attaaattgt tttaatcaaa ttccaatcta aatatttgta gaaaacaatc
     2221 gtctcctata gaataaattt ataagtaaca atataccaat cataaatcta tttgctagga
     2281 ggaatttaca tggaagagaa aaatttaacg gtcatcggaa gctatagtac gagggaagaa
     2341 gcattatcag taattgaacg gttgcgtaac gaagggtatg aacgagatga tatcgttatt
     2401 tatactactg atgaagcagc atctagacta ggatttgacg gattgtctgg tatagatgtt
     2461 gaaacagatg aaaatcggat ggatggtgaa gaagaccgtt ctttatggga aaaaataaaa
     2521 gatacttttt cttttgatac ctatgattct gagacggcta caccagaaaa tgatccttta
     2581 tatcaatata gaggagatat ttctgatgga aaatttgtca tcacagtaaa aggctatcgt
     2641 cagccagaaa caacagaaga tacaatggat acacaagata ctgttagccc agcaagcaca
     2701 atggggactg gattagaaac tggcactgga acagatccaa tggacgtagg tggcacgaca
     2761 ggctttcaaa atacaacgga tccattgaat atgacaccag gaactgatcc gatggacgta
     2821 cctggcgaga ctgatacaat gggtacaagc aagactgaag acatcgatcg caaaccaaat
     2881 ctagatgatg atacaattca actaaaagaa gaaaaattag atgtaaatac acatgatgtg
     2941 acaactggag aagtcgacat ccacaaacat gtggtcaacg atactgaaac ggtagaagta
     3001 ccggtcaaac gtgaagaaat cgtcatcgaa cgcaaaccag taacagatca atcttcacag
     3061 ggaacagacg aaaaattgga agatgacacg attactatcc caatcaaaga agagcaagta
     3121 gatgtaagca aacatacagt tattcgtgaa gaagttggga ttcataaaga agaacatgaa
     3181 gatgttgaaa aagtgacaga agatgttagc cgagaagaat tggatattga cacaagcggt
     3241 gatgtacaca ttgaagaccg caataaaaaa tcgtaagcgt aagctaaaga ggttgtgaca
     3301 gaagtggtca gcttaaagaa atttcggctt attt
//
LOCUS       DACGMI010000127         3177 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.135, whole genome shotgun sequence.
ACCESSION   DACGMI010000127 DACGMI010000000
VERSION     DACGMI010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.135"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..234
                     /locus_tag="IXT46_002928"
     CDS             <1..234
                     /locus_tag="IXT46_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948791.1"
                     /translation="SHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFMDYQKLDQLI
                     ERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            851..>3177
                     /gene="esp"
                     /locus_tag="IXT46_002929"
     CDS             851..>3177
                     /gene="esp"
                     /locus_tag="IXT46_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HAQ4948792.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
BASE COUNT         1164 a          468 c          612 g          933 t
ORIGIN      
        1 agtcatatta atggtagcaa ttttaaacaa acattattta atctgattaa gctagatgct
       61 aaaatatcaa gttatttatt ctttttgata catgatgaat ttatggatta tcaaaaattg
      121 gatcagttaa ttgaaagaga aagctgggaa gattattacg tgggtctaac tttttcagaa
      181 aagttaaaca actacaagtt aatagattat aagtatttga gtgaaagcaa ttaattattc
      241 atgtagagta ctagacactt taaatatgga caattcaatt ataaagaaaa agaatcaata
      301 atttaatgag gctgtgacaa atgtcatttt ttgtttcgct aaaaacgagt gaaaaaatgt
      361 tgataactcc aatcattcgt ttaagattct aggaatcatt cagaaatgct gtgaaaccga
      421 tactttataa ttataaagaa ggtgatttca aattccgaag aaggaatttg aagtcacctt
      481 tttacttatg tcacagtctc attcagtaat gcgggataag gctccttatt ccgttatttg
      541 aatactctga agtttaatct aagaaagggt aatattttga aaacatgctt catcgcatag
      601 aaatgaactt aatttcagaa agaatacata catatctttt tatatgtttt cagctgctga
      661 atggttaaaa agcacaaata tccgaaaaaa acatgaagaa atgtactttt tttgttgtaa
      721 tgttcatgaa attctctaag taaattagtt aacataaggt tagtaagatt cctattctgt
      781 gaataatacg tatcagattt atcttttatt cttactagga aagtaattat taagggagtt
      841 gatttgaata atggttagca agaataataa gagagtattt ctagaaaaaa caaagaaacg
      901 agtattgaag tacagtatca aaaaattaag tgttggggtt gcatctgttt tgattggtgt
      961 tggtcttgtc ttgggaacaa ctgaactagt taaagcacaa gatgaaattt ctccaagcag
     1021 cccacttgaa acagcgataa gctccgtaca agtaggtgac aaagtagctt cggggaatac
     1081 ttttcaggag aatcctggtt atacgaaaaa ttataacttt tcggatttac aatttagtcc
     1141 tcaagaacta actggagaca cactaaaagg caatacaatt ggatttgaag tttacggaaa
     1201 acataatatt gcagcatcaa ctaaaaactg ggaaatccgt cttcaattag atgaacgatt
     1261 agctaaatat gtagaaaaaa ttcaggtcga tccaaagaaa ggaattggat cttctagacg
     1321 gacctttgta agaattaatg attcgctggg tagacctaca aatatttgga aggtcaatta
     1381 tattcgtgca agtgatggat tatttgctgg ggcagaaaca accgatacgc aaaccgctcc
     1441 taatggggta attacgtttg aaaagagcct agatgaaatt tttaaagaga taggcataga
     1501 caatctcaag accgatcgtt taatgtatcg aatctacttg gtaagtcatc aagacgatga
     1561 taaaattgta ccgggtattg atagtacggg ctacttttta acagattcag atgatttcta
     1621 taatagctta gatgtatctg aaaataatcc tgaccagttt aaacatggat cagtaagtgc
     1681 aaaatatgag aaacctaata ctcaaacaaa agatggttca ggatccacag gtgctaatgg
     1741 agctataatc ttagatcata agttaacgaa aaattataat ttctcatatt catcttccgc
     1801 aaagggcacg ccttggtatg ctaattacaa aattgatgaa cgattagttc catatgtagc
     1861 gggtatacag atgcacatgg ttcaggctga caaagtaaca tatgatgttt cgtttgaatc
     1921 cggaacaaaa gtagctgatt tagcaatcga gcgacgggaa ggtcatgaaa attatggcat
     1981 aggttcaata actaataatg atttaactaa acttatcgat tttgctaatg caagtccacg
     2041 tccagtcgtt attcgatatg ttttacaatt gactaagcca ttagatgaaa tcttagaaga
     2101 tatgaaagca acagcacaag ttgaagaaaa taaaccattt ggtgaagatt tcatctttga
     2161 ttcttggttg tcggatacga ataaaaaatt aatccagaac acttatggaa caggttatta
     2221 ttatttgcaa gatattgatg gtgatggaaa ccctgacgat aaagaagaga gcggagacac
     2281 gaatccatat atcgggaaac ctgaattaga agaagtatat gatgttgaca caacagttaa
     2341 ggggaaagta ttcatccacg agttagcggg aacaggtcac aaagcccaac ttgttgataa
     2401 agaaggtact gtattagcag aaaaaactat cgctccaaat gaaaaagatg gggctccaat
     2461 ttcagatact gtagaatttg aatttacggg tgtagattca agtaaattaa tcgcgaaaga
     2521 tgaattaaaa atccaaatcg tttctccagg ttttgataaa ccagaagaag gttcaaccgt
     2581 tattaaggaa tcaccaaaag cggttgataa acaaaccgtg gtagttggat ttaaaccaga
     2641 tgctaaagaa tcaattcgga ataataaaaa cttacctgaa gatgcagagt attcatggaa
     2701 aacagagcct gatacttcta acgttactga tagtacgaaa ggtattgtaa ctgttaagat
     2761 cggaaatcga actttcgacg tggatgtaga gtttgctgta aaagcttctc aagctatgga
     2821 aaatgatgca acatacgtac ctataacaac aactccagaa acgacagttc aaagtggaaa
     2881 acctacattt gataaaccag atgttccttt agctaaagat gccttttcaa tttcagatgt
     2941 ctataataag gacttcggta atgcaagtgt tgatgcaaac actggtattg ttacattcac
     3001 tccagctaaa ggtgtaggag aatcggagcc gattactgga acaattccta ttaaaattgt
     3061 ttaccaagat ggttctgtag gcacgaccga tttagcagta actgtaagta aagatattta
     3121 tgaaaatcca ggagaaaaca ttcctgcagg ctaccacaaa gtaaccttca ccgcagg
//
LOCUS       DACGMI010000128         3012 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.136, whole genome shotgun sequence.
ACCESSION   DACGMI010000128 DACGMI010000000
VERSION     DACGMI010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3012
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.136"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            178..360
                     /locus_tag="IXT46_002930"
     CDS             178..360
                     /locus_tag="IXT46_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HAQ4948793.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKAIGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            463..747
                     /locus_tag="IXT46_002931"
     CDS             463..747
                     /locus_tag="IXT46_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948794.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            763..999
                     /locus_tag="IXT46_002932"
     CDS             763..999
                     /locus_tag="IXT46_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948795.1"
                     /translation="MEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTSLEC
                     VWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            1021..1275
                     /locus_tag="IXT46_002933"
     CDS             1021..1275
                     /locus_tag="IXT46_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948796.1"
                     /translation="MNYTDEEQIALEYVFTNEEGEEIEKVLIISSKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            1357..1542
                     /locus_tag="IXT46_002934"
     CDS             1357..1542
                     /locus_tag="IXT46_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HAQ4948797.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            1609..2004
                     /locus_tag="IXT46_002935"
     CDS             1609..2004
                     /locus_tag="IXT46_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAQ4948798.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            1994..2371
                     /locus_tag="IXT46_002936"
     CDS             1994..2371
                     /locus_tag="IXT46_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948799.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            2372..2767
                     /locus_tag="IXT46_002937"
     CDS             2372..2767
                     /locus_tag="IXT46_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948800.1"
                     /translation="MKQEKRKMKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLW
                     KYKILFLFWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVIS
                     DAGIERNIKRVSFKITLNKPTDKKLSEAF"
BASE COUNT         1059 a          507 c          524 g          922 t
ORIGIN      
        1 gtttatgttt atgtatatgt atatgaatat aaacgtatta ggtacgaaca cttttaaatt
       61 cttttctggg ctttgttttt agggtagggc taaaaaaaac atcaccatct gatccaaaac
      121 agctcagaaa cgcatttaaa cgtatctgat accaatatta cagaaggagt gtatcgtatg
      181 attaacctat ttcttttagt gacagctagt acattattct ttactggaat atcactgata
      241 atttcctatt tgatctataa gaaagccgaa aatcacacaa gcaaagcaat cggactagcc
      301 gtttcatcct ttttaacttt gctgacttta tttgttactt tatcgttttc ttttgtttag
      361 aacagctgat ccattagcac ctttttctct ttacattata cacactgttg tgtataatgt
      421 atttgtaaac aagctaatta acttttagga aggagtgaca agatgctaac agctacttta
      481 cagcaaccta ctcacgttgc tattgcagaa agttatacaa ttaatgcagg gatcgttaaa
      541 cagctgatca aggatcgaga attcaaaaag tttaacagtc ggcaagcgta taacagacag
      601 ctaaagaaag ctattctaaa gcacaaagat tccttcatcg ggaacttgga aagtgtagat
      661 gttaaaactg tttcaacggc attttcagtt gttgaagtga ctattgacgg tcgcttgatt
      721 tctctatttg cttttggaat taattgatag ggagtgtgaa ctttggaagg taagactttt
      781 gcagaaattt ggactgaatt tattgaggta ccaactcgca ttgatccgat aacttctgaa
      841 aaggtattgg atgcagactt ctacaatctc aaagcaggta ctagccttga atgcgtttgg
      901 atgtatttag aagagcattt caaaggcgta acgctcggtc acgtcttata ccacaatggt
      961 gccgagtggg atgcaattgg aaatatccat ttttcttaat ataagaaagg agaacacaat
     1021 atgaattata ccgatgaaga acaaatcgct ttggaatacg ttttcacaaa tgaagaaggg
     1081 gaggaaattg aaaaagtctt gatcatttca tcaaaagact tggagaaggc tttggcttat
     1141 gaaccatacg aatcaaccgt aactgtcatt gaattcttag atacctatac ttctaatgat
     1201 acttgggaaa ttatgaatat ttgcaacgct aataacattc aatttgctga aaaaaccaat
     1261 aaatcatttt attagttttg caataaaaca tcctcttttt ctattgattc catacacaac
     1321 aatgtgtata atagattttg taaagggagg gtagctatgc ctaagacagc aagagaaatt
     1381 gtaaaaattc tcaaatctaa cggcttcaaa aagactggac aaactggcag tcatgcaaaa
     1441 ttttataatt ccaagactaa aagaacggtc gttgttccga tccacaatgg tgatgtacca
     1501 ctaggaacag aagctaatat ctggaagcaa gcagggcttt aacagccttg ccttcctatt
     1561 tggtattagg catactatcc tctcttacac tagaaaagga gcgaggaaat gaagacaaaa
     1621 aatatttttt atccggcaat cttcgagaaa gaaggagaag cttataacat cgttttccct
     1681 gacttaccgg aaatatctac ctttggaaat agtcttgaag aagcatattt aaacgctaag
     1741 gatgctttag gattagcgct atatagtgta ccagatgcag aatttcctaa accatcagca
     1801 gtggaagaat taactttgaa agccaaccaa gtggtagtaa tcatccaact aaacattaaa
     1861 cttttccgaa gaagcttaaa tacaaaaaca attagaaaaa atgttagtgt tccggaatgg
     1921 ttagttcttt tagggaagga gaaaaacata aacttctctc aactacttca aaaagcacta
     1981 gaagaagagt tgcttgaaaa gtaaaaagga gaccgaacct atgaaagcta cacacttaaa
     2041 ctatttctct cgaacgttaa tcaataatct attaaaagat acaactggca ttagcgttag
     2101 taccaaacac tttgccaatg atctaattat ttttgaggat aataacttgc gaattgagat
     2161 gtttattgaa caggcaaccc ctaactcaat acctgaattc tgctatacgc acactgaaaa
     2221 aatgaaacat gcaaaatcag ttaaagatgt tgaagcatta agtgaatcac taacgaacgc
     2281 tttaaacctc gttaagaagg caaaattgtt atttgaattt caaaccgact accacaatga
     2341 gttgcttgct caatctgaaa ttttagatta attgaaacag gagaagagaa agatgaaaca
     2401 aacacaaaca gaaaccgtta acgatacgct tgctgatcaa ttagcaggtt attataaatt
     2461 atttgagatg ggtaaagcac agcgcttgat ccactatctt tggaaataca aaattttgtt
     2521 tcttttttgg gaatcaacac taacattctc agttcttttt tataagtcag atttttataa
     2581 tcaacactta gttttaggga gttttttgct tatctacacc attttgatgc ttaatttata
     2641 tacctacatc acacttgaag aacacttagt aattagcgat gcagggatcg agagaaacat
     2701 caaaagggta tccttcaaga tcacgttaaa caagcctacc gataaaaagc tctcagaagc
     2761 gttctgagag cttttgacat tttcttgtat aattttatcc taacacatta caaagcacct
     2821 aattcgagct tatatcaagc aaatttgcta tttattactc aatacatatc taaaaattac
     2881 ttgatggaaa attagataca tggtaagcat gaaaagaaaa tcaatttgag cagatgcagt
     2941 acaatacata gcaatttaaa agctctcaga aggcttctga gagcttttaa tatattcttt
     3001 gataatttgt ct
//
LOCUS       DACGMI010000129         2870 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.138, whole genome shotgun sequence.
ACCESSION   DACGMI010000129 DACGMI010000000
VERSION     DACGMI010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.138"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            256..1224
                     /locus_tag="IXT46_002938"
     CDS             256..1224
                     /locus_tag="IXT46_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAQ4948801.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1217..2248
                     /gene="vanA"
                     /locus_tag="IXT46_002939"
     CDS             1217..2248
                     /gene="vanA"
                     /locus_tag="IXT46_002939"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAQ4948802.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2254..2862
                     /locus_tag="IXT46_002940"
     CDS             2254..2862
                     /locus_tag="IXT46_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAQ4948803.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          847 a          549 c          702 g          772 t
ORIGIN      
        1 ttccagcgat gccagacttg gttgataaaa ggaggtccta agagatgtat ataatttttt
       61 aggaaaatct caaggttatc tttacttttt cttaggaaat taacaattta atattaagaa
      121 acggctcgtt cttacacggt agacttaata ccgtaagaac gagccgtttt cgttcttcag
      181 agaaagattt gacaagatta ccattggcat ccccgtttta tttggtgcct ttcacagaaa
      241 gggttggtct taattatgaa taacatcggc attactgttt atggatgtga gcaggatgag
      301 gcagatgcat tccatgctct ttcgcctcgc tttggcgtta tggcaacgat aattaacgcc
      361 aacgtgtcgg aatccaacgc caaatccgcg cctttcaatc aatgtatcag tgtgggacat
      421 aaatcagaga tttccgcctc tattcttctt gcgctgaaga gagccggtgt gaaatatatt
      481 tctacccgaa gcatcggctg caatcatata gatacaactg ctgctaagag aatgggcatc
      541 actgtcgaca atgtggcgta ctcgccggat agcgttgccg attatactat gatgctaatt
      601 cttatggcag tacgcaacgt aaaatcgatt gtgcgctctg tggaaaaaca tgatttcagg
      661 ttggacagcg accgtggcaa ggtactcagc gacatgacag ttggtgtggt gggaacgggc
      721 cagataggca aagcggttat tgagcggctg cgaggatttg gatgtaaagt gttggcttat
      781 agtcgcagcc gaagtataga ggtaaactat gtaccgtttg atgagttgct gcaaaatagc
      841 gatatcgtta cgcttcatgt gccgctcaat acggatacgc actatattat cagccacgaa
      901 caaatacaga gaatgaagca aggagcattt cttatcaata ctgggcgcgg tccacttgta
      961 gatacctatg agttggttaa agcattagaa aacgggaaac tgggcggtgc cgcattggat
     1021 gtattggaag gagaggaaga gtttttctac tctgattgca cccaaaaacc aattgataat
     1081 caatttttac ttaaacttca aagaatgcct aacgtgataa tcacaccgca tacggcctat
     1141 tataccgagc aagcgttgcg tgataccgtt gaaaaaacca ttaaaaactg tttggatttt
     1201 gaaaggagac aggagcatga atagaataaa agttgcaata ctgtttgggg gttgctcaga
     1261 ggagcatgac gtatcggtaa aatctgcaat agagatagcc gctaacatta ataaagaaaa
     1321 atacgagccg ttatacattg gaattacgaa atctggtgta tggaaaatgt gcgaaaaacc
     1381 ttgcgcggaa tgggaaaacg acaattgcta ttcagctgta ctctcgccgg ataaaaaaat
     1441 gcacggatta cttgttaaaa agaaccatga atatgaaatc aaccatgttg atgtagcatt
     1501 ttcagctttg catggcaagt caggtgaaga tggatccata caaggtctgt ttgaattgtc
     1561 cggtatccct tttgtaggct gcgatattca aagctcagca atttgtatgg acaaatcgtt
     1621 gacatacatc gttgcgaaaa atgctgggat agctactccc gccttttggg ttattaataa
     1681 agatgatagg ccggtggcag ctacgtttac ctatcctgtt tttgttaagc cggcgcgttc
     1741 aggctcatcc ttcggtgtga aaaaagtcaa tagcgcggac gaattggact acgcaattga
     1801 atcggcaaga caatatgaca gcaaaatctt aattgagcag gctgtttcgg gctgtgaggt
     1861 cggttgtgcg gtattgggaa acagtgccgc gttagttgtt ggcgaggtgg accaaatcag
     1921 gctgcagtac ggaatctttc gtattcatca ggaagtcgag ccggaaaaag gctctgaaaa
     1981 cgcagttata accgttcccg cagacctttc agcagaggag cgaggacgga tacaggaaac
     2041 ggcaaaaaaa atatataaag cgctcggctg tagaggtcta gcccgtgtgg atatgttttt
     2101 acaagataac ggccgcattg tactgaacga agtcaatact ctgcccggtt tcacgtcata
     2161 cagtcgttat ccccgtatga tggccgctgc aggtattgca cttcccgaac tgattgaccg
     2221 cttgatcgta ttagcgttaa aggggtgata agcatggaaa taggatttac ttttttagat
     2281 gaaatagtac acggtgttcg ttgggacgct aaatatgcca cttgggataa tttcaccgga
     2341 aaaccggttg acggttatga agtaaatcgc attgtaggga catacgagtt ggctgaatcg
     2401 cttttgaagg caaaagaact ggctgctacc caagggtacg gattgcttct atgggacggt
     2461 taccgtccta agcgtgctgt aaactgtttt atgcaatggg ctgcacagcc ggaaaataac
     2521 ctgacaaagg aaagttatta tcccaatatt gaccgaactg agatgatttc aaaaggatac
     2581 gtggcttcaa aatcaagcca tagccgcggc agtgccattg atcttacgct ttatcgatta
     2641 gacacgggtg agcttgtacc aatggggagc cgatttgatt ttatggatga acgctctcat
     2701 catgcggcaa atggaatatc atgcaatgaa gcgcaaaatc gcagacgttt gcgctccatc
     2761 atggaaaaca gtgggtttga agcatatagc ctcgaatggt ggcactatgt attaagagac
     2821 gaaccatacc ccaatagcta ttttgatttc cccgttaaat aaacttttaa
//
LOCUS       DACGMI010000130         2719 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.139, whole genome shotgun sequence.
ACCESSION   DACGMI010000130 DACGMI010000000
VERSION     DACGMI010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.139"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="IXT46_002941"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="IXT46_002941"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAQ4948804.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1065 a          420 c          556 g          678 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatca
//
LOCUS       DACGMI010000131         2621 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.140, whole genome shotgun sequence.
ACCESSION   DACGMI010000131 DACGMI010000000
VERSION     DACGMI010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.140"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(45..1364)
                     /locus_tag="IXT46_002942"
     CDS             complement(45..1364)
                     /locus_tag="IXT46_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4948805.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="IXT46_002943"
     CDS             complement(1361..2014)
                     /locus_tag="IXT46_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4948806.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..>2621
                     /locus_tag="IXT46_002944"
     CDS             2302..>2621
                     /locus_tag="IXT46_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4948807.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLT"
BASE COUNT          869 a          412 c          257 g         1083 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgaca ccttctgttg
     2101 ccaatacttt ttcttttttc taataaatgc aaacagacac cttgaaatcc tttagaataa
     2161 agggttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tattgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa c
//
LOCUS       DACGMI010000132         2483 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.141, whole genome shotgun sequence.
ACCESSION   DACGMI010000132 DACGMI010000000
VERSION     DACGMI010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.141"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(1014..1304)
                     /locus_tag="IXT46_002945"
     CDS             complement(1014..1304)
                     /locus_tag="IXT46_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948808.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2203)
                     /locus_tag="IXT46_002946"
                     /pseudo
     CDS             complement(1512..2203)
                     /locus_tag="IXT46_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          734 a          458 c          348 g          943 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgatttct acatttgttt
     1681 tttcttgtgt cagtgttgcg atttgttgat tcaaaccatt tacagtattt tgtaattctg
     1741 aaagttttgc ttgtgcttct tgtagtcttg ctgtccaatc tgcattcaga tgattgattt
     1801 catcattttt ttggttgatc tcatctagtt tgacattgat ttcattttgt ttgctttgta
     1861 gttgtgcatc cttgctgact aattgacttt ctaagttttg tttttctgct gccgattgat
     1921 ttttttggtt ttctaattca tttacttttg tttggtattc ttggacatct gcctttgaat
     1981 cttgcaatgt ctgttctttt tgtgctagtc gagcggtaag atctgtaatc gcttgctctt
     2041 tatctgtcaa tgtatgatca agctgtgtca gattctcatt gattgtatca atatctgtct
     2101 ctccacccca caaaataatt tcatttgcgt accgcgtgcc tgtgtagcca attagacata
     2161 gaaatgcaac gacaatccca ccagtaataa atttcttttt catttgcata gctccttaat
     2221 ccaatacttt tacatgctaa aagtaagtga tctcaaacac aatgtcaagc gtttttaaat
     2281 tacatatgta attttaatat aaatactatc aaatactcat ttaatcctcc ttttttatct
     2341 atttaaaaaa tcttttttat agagaaaaat gcaggttaat actttcttaa ataaatattt
     2401 atggtgaaca aaaacaaaaa agcaagtttt attaaacgta acccttttca tttcatagat
     2461 tactgtattt attacaaaaa acg
//
LOCUS       DACGMI010000133         2398 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.142, whole genome shotgun sequence.
ACCESSION   DACGMI010000133 DACGMI010000000
VERSION     DACGMI010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.142"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            207..2069
                     /locus_tag="IXT46_002947"
     CDS             207..2069
                     /locus_tag="IXT46_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4948809.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="IXT46_002948"
     CDS             2069..>2398
                     /locus_tag="IXT46_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4948810.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DACGMI010000134         2369 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.144, whole genome shotgun sequence.
ACCESSION   DACGMI010000134 DACGMI010000000
VERSION     DACGMI010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2369
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.144"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            221..655
                     /locus_tag="IXT46_002949"
     CDS             221..655
                     /locus_tag="IXT46_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4948811.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            678..998
                     /locus_tag="IXT46_002950"
     CDS             678..998
                     /locus_tag="IXT46_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948812.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1139..1330
                     /locus_tag="IXT46_002951"
     CDS             1139..1330
                     /locus_tag="IXT46_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948813.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1401..1658)
                     /locus_tag="IXT46_002952"
     CDS             complement(1401..1658)
                     /locus_tag="IXT46_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAQ4948814.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            1816..2079
                     /locus_tag="IXT46_002953"
     CDS             1816..2079
                     /locus_tag="IXT46_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948815.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2103..2291
                     /locus_tag="IXT46_002954"
     CDS             2103..2291
                     /locus_tag="IXT46_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948816.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
BASE COUNT          921 a          331 c          491 g          626 t
ORIGIN      
        1 cgttttttgt aacagaatga tgttcgctcg atgtgaaaaa tgatgaggaa tttcacataa
       61 tgcagaaata atgggattag aacaggtgtt ctgatgagaa aagaaatgta taaataactt
      121 gaaagaaatt gcttttgttc atcattttat ttacatattg cgtatatttt ttgtattttt
      181 gcttgagatg ttacaataaa agaaaaagga ggcggttcca atgagtaaaa gataccagaa
      241 catcatggta gcagttgacg gatcaagaca atcgatcaaa gcgttcgctg aagcccttga
      301 cttagcaaag gacaatgaag cccacttatt tatcgtgtca atcatcaaca aagttgagct
      361 gacccatagt gcctatgcct tttcaaaaat ctatgcagat gaaaaacaaa gaacagaagt
      421 agccatgctg aaaaaaatca atgatgccaa agagtacggc attgctgaga tccacgcaat
      481 agttgaaact ggagatccaa gaaatttgat tgccaatgtc atccctggac aagaaaatat
      541 tgatttgatc gttatgggag cgacaggaaa aggtgctata caacaagcat tagttggatc
      601 gaccgcttct tatgtcgtat cacatgcccc ttgcagtgtg ttggtcgtga agtaatgaga
      661 taagggagga atagaaaatg gttcgtcctc aagaagtccg tgcgccaaaa gaaaaaatag
      721 aaattttagc aattattgaa gacggcacac aaacaaagaa gggatactcg atcgctttag
      781 taaagtggaa aggaaaaaaa ggtgttgctc tgagatggga tggagataac caacaagata
      841 aaggattccc tgtcacagct aacggttatc atccagcgtg gtttgttctg cctgataaat
      901 ttatggaatt atacagctat gattatgcaa gagccgcagc atcaatcaaa gcattagata
      961 aattaacaga agagcagaat gaaatggagg aaaaataaaa aagacgaacc aatcagcctt
     1021 tagaaaactg attagttcga ggagtaaaaa tgaaaaaagg ttatttggga tgaaactaga
     1081 ataatgcgta taacttaaat aaaacttaaa gcaataaaat ggcaagaggg tgaggcaaat
     1141 ggaagcagga aaagtattac aggaagtaaa agcactatgt gcagataaaa aatatgaaga
     1201 agcgaaaagc ctgatcgaaa agaacaaaga aaatttggaa gaaaagtacc cgatcgcaca
     1261 agaatttata gaattaaaac aaggaacgat ccttcaccga ttcaaacatt tttttggtat
     1321 aacagaatag aaaaaacgat taaagatcgg cagaaatttg ctgcatcttt aatcgttttc
     1381 tttttaaaca tgcgagggat tcaattctga ttcttatata aaaaatagat ccaaataata
     1441 agaaaaatta ctgaaagcgt caattcgatg atgtgtgtta ttaatacaga cgttgtttcc
     1501 caatgcctaa aagaaaaaat ttgataagta aaatatacag caggtaaaga ggccagtaaa
     1561 actgaaaact tcttttttgt ccattttatg taatagaaaa gaatgcttat cataataaaa
     1621 aaaggaatat aaaaaacaaa ttgaccgatc gcgatcatac tattgcctcc gataaataaa
     1681 gtccatgata caaaataaca ctttgtgcga aatggcgcaa gcagttttgt ggatttatcc
     1741 ggtaaaatct gtatcgattt tgaaattaga ggagaaactt gctataatca aagtgaaaga
     1801 aggagtggga ttttcatgga tcatgtagtg ttagaaatcg atttgcattt gatcaataat
     1861 attcgggtga tttactatgt tgtaagtaac agtgtcgaac aacgtgtact gacgaataaa
     1921 ataaatggta ttttagcaaa gaaagacgtt caccgattca ataatggtga aggaagttat
     1981 tatagtatcc cagtagaaaa aattatttat acgacagtca aagtcagaga agatctagat
     2041 accaaaaaag catatgaacc tatttttaca acttattgat tgacagcaga tggaggaaaa
     2101 aaatgaatcc atatgaacaa cttattcaag atttgatcga tggaaaaatc gaaaagattg
     2161 atgtaaaaag agaagaatta atggcttttc gagaagcgtg gctgaagttg gagaatcgta
     2221 aatatgtggt gggaaaagcc tcactgaacg gcaatgtgac ttatcattac gatccgacac
     2281 gtttatttta gtatgaagta ttcagaaaag aacggctctt tgtcaaatag gactgataga
     2341 gtgagataag aacatctaag gtagaattc
//
LOCUS       DACGMI010000135         2313 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.145, whole genome shotgun sequence.
ACCESSION   DACGMI010000135 DACGMI010000000
VERSION     DACGMI010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.145"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            191..445
                     /locus_tag="IXT46_002955"
     CDS             191..445
                     /locus_tag="IXT46_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4948817.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="IXT46_002956"
     CDS             446..763
                     /locus_tag="IXT46_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4948818.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1322..2257
                     /locus_tag="IXT46_002957"
     CDS             1322..2257
                     /locus_tag="IXT46_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948819.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          846 a          313 c          434 g          720 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     1441 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     1501 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     1561 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga
     1621 atatctcaag gggaatagct atctcaagat tcgattttca catatattaa ttttactacc
     1681 atatttgaat gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa
     1741 tcaaggaaat atgaatatta caagtaacaa aacgtcacgt gtgctattgg cgttgatggg
     1801 ttacggaatt ctttatagag atgaccaaaa tggccagatt ctaataaatc gggctgggcg
     1861 ttcattatta atgaaatata gaaaatttat accggaagat tttcaaaact tacagttaga
     1921 aaacatgcgt ttagaagatt tatttagatt agcagaagat gataagtata gatttgaagt
     1981 tttgaaaatt caaaagaatg aactattgaa taagttatat cctgagaatg cgataaaagc
     2041 acattttggt gatgctaatc atatgtatag ttggttcatt cctaaaagat ttagagggaa
     2101 aatcaatgct ggagatcaag tgaaagtact caatcgaaat agtacagatg tcgtaatgat
     2161 aacagatatc tatgtagaag atgaagatat aatcaaatat atgaagcctg tgataaaact
     2221 tgttaataaa aataaaggaa cccgtggtgc tagttaattt tttcctagag aaaaatgtct
     2281 aaacatgttg gtaaatcaac aaaaaaacgc ata
//
LOCUS       DACGMI010000136         2293 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.146, whole genome shotgun sequence.
ACCESSION   DACGMI010000136 DACGMI010000000
VERSION     DACGMI010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.146"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(51..1598)
                     /locus_tag="IXT46_002958"
     CDS             complement(51..1598)
                     /locus_tag="IXT46_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAQ4948820.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="IXT46_002959"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="IXT46_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAQ4948821.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="IXT46_002960"
     CDS             complement(2043..2237)
                     /locus_tag="IXT46_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948822.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          644 a          477 c          408 g          764 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga aaacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agt
//
LOCUS       DACGMI010000137         2259 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.147, whole genome shotgun sequence.
ACCESSION   DACGMI010000137 DACGMI010000000
VERSION     DACGMI010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.147"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(148..2145)
                     /locus_tag="IXT46_002961"
     CDS             complement(148..2145)
                     /locus_tag="IXT46_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAQ4948823.1"
                     /translation="MIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKA
                     LVTNKANQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHL
                     KEATKRLSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVY
                     IKNSGVTDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADE
                     AEKYLAKGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGS
                     NLMLSMNAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHE
                     QGSKEITENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKS
                     SVFNRSGQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRD
                     SFKEFGLGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYT
                     PIQLAQYASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMA
                     ILREGFHQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGP
                     TDNPEIAISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          574 a          505 c          411 g          769 t
ORIGIN      
        1 ttttgtcaca accttttttg ccgagtaaac ggtgttcaaa agccagtttc tcggtatgaa
       61 gtcaaattta agcaaaaatg tgagaagcta ttttcacaaa atttttcttc atactcgaaa
      121 ctaagcggct ttttcacgac ctctttttta ttttgccatg aacatatcat aatacgcgtc
      181 cattatttct ttagcaatcg tcaagtttat gtggtcttgt tcgtctaata agttcggcaa
      241 gacaacactg atggcaattt ccggattgtc tgttggtccg tatgccacga tattactatt
      301 gactgtcgca atatctggat gaccttccgc aaccgtttct gcagtccctg tttttgcgga
      361 aaggtccatt ttcgcactgg ctaatggttt ggctgttgtg taaggatcgg taccatggac
      421 aacttggtgg aatccttcac ggaggatcgc catattttct gcagaaatat tgaccgtatt
      481 ttctactgtt gtgccaattt ctttcttcac ttcacccaag tttccatttt cgtcattgcc
      541 atagatcgct ttgactaggt gcggctgtac tcgtttcccg ccattagcga ctgttgaagc
      601 atattgagct aattggattg gtgtatatgt gtcaaactgt ccaaatgcca aatcggtaaa
      661 gttacctgga gcataccatt ctttgccatt atccgcattg aacttcttca tataatcaac
      721 agaacgtgag atcccaggag attcattcgg caaatcgatc ccagtcgttg taccaagacc
      781 aaactctttg aaagagtctc tcaattgctg ataagcttta gcttcttcat ctaaactagg
      841 tagtcccatt ccaggtgtat agtctagtcc taacatcttt aacgccactt tgatcatata
      901 cgtattagaa gacaattccg atgctttgac tgcatcaaga gcaacttgtc cgcttcgatt
      961 aaagacagag cttttttctg aagcaccttg cagacgaatc ggctcatcaa tcaaaacttg
     1021 atttccgctg atcgcgttac ttgcccagcc tgctgtcaaa gtaccagcct tgactacaga
     1081 ccctggatca aaggcgctag taatcgtgcc taaagcattc tcggtgattt ctttggaacc
     1141 ttgttcatga ctgaaaccag tcattgctag cacttctcct gtctgaggat tcatagccac
     1201 tgcataagca ccaggcgaat actgtgcttt gccgttgttg atcaatgttt gataattcct
     1261 tttcaaaatt tcttctactt ttgattggaa ttctgcattc atagataaca ttaaattaga
     1321 acctttttcc ccagagaaga tttctttttg attcgaaaca tttccttcat tatcaaggga
     1381 aacttcatat tgggttttgg ttccttgcag gacatcttca tattgttttt ccaaataact
     1441 ttgtcctaca cggtcattcc gagaataacc ttttgctagg tatttctctg cttcatctgc
     1501 tggaagtcct tgcttttcag tcgtcacact gccaagaata cttttcagtg aacttgctgc
     1561 attatattct cgtgtccagt ctgtgccagt cgaaactcct ggaagttcag aagcgcgttc
     1621 tgccacaaca gctaactctt gatcagtaac accagagttt ttgatataga cagtgtttaa
     1681 ttcatatgca ctattcatcc gtttaaagat ggtagcaatt tttaattgct cctcgtttaa
     1741 attaatctca tcagctgtga ctttattgac catcgcacta tattgttcgc tgttccctaa
     1801 ttgcttttct tttgccgaaa gtctttttgt ggcttctttc aaatgtttgg gatcagccag
     1861 ccaaaaatct tttttatctc tatctgtcag attttcatct accggaacat cgatcagcga
     1921 gttcagcttc gttgcgattt caagcaaatc tttagccgta acttgtgttc ctctcgtata
     1981 tgtgatggcc tgattcgctt tattcgtaac taaagctttt cctgtggagt cgtagatcat
     2041 tccgcgagga gtactttctt ggaccgtaat cgtagaagta gacttcactc gcgcctccat
     2101 ctcttcgccg ttcacgatct gcaaataacc caatctagca atcaacgcaa caaataacgt
     2161 aaatataatg aaaaaaagaa aatttaagcg aaaaggaaca tgggaccggc gaaacgtttt
     2221 gttcttaggt tcttgtgcac cttttcttat tttttctaa
//
LOCUS       DACGMI010000138         1933 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.149, whole genome shotgun sequence.
ACCESSION   DACGMI010000138 DACGMI010000000
VERSION     DACGMI010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.149"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(210..695)
                     /gene="vanZ"
                     /locus_tag="IXT46_002962"
     CDS             complement(210..695)
                     /gene="vanZ"
                     /locus_tag="IXT46_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAQ4948824.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(848..1759)
                     /locus_tag="IXT46_002963"
     CDS             complement(848..1759)
                     /locus_tag="IXT46_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HAQ4948825.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT          607 a          374 c          264 g          688 t
ORIGIN      
        1 atttattaaa gagaccaatt cctcagcact aaaattgata attgggcttt ctttgttact
       61 atagtgttag gtaagctttt tactttatca ccggttttcc cctcacttca cacctacggg
      121 cgagtttccc cacatcccgt tttccatcta atccaattca ttcaatatct ttatgtgtat
      181 gaaagatcag attgcttgat ttagacatct tacacgtaat ttattcttaa atgggtacgg
      241 taaacgagca ataatacgag caaaagtata cctacaaaaa taataactct gtctaatttt
      301 ttttgattca tatgcttatt gcttaaacca tataatttca gtccaagaaa gcctccaaca
      361 gtatttgtaa ttacatctgt tatgtctgtc gctccaatag cgaagataaa ttgaattatt
      421 tcaaaagtaa gacttaaaac cagtacaaaa gcaaacttag gtaaaaatcc gatttcttta
      481 aaattgacat tcaaaagcaa gccaaatgga ataaagatta taacattatc tatcatctct
      541 ctgaaattcc cagtagcagt aaatggagtc aagttaagac ttctttgatg ataattaaat
      601 actgataaaa tattgtattg taatttgaat aacactaacc agattagtgt cactaaatat
      661 aaagctagca atcctctaga taatattttt cccaatataa tttcctctaa ttcttttgtt
      721 taagttgtat cattagtata gcaatgtcct agttaacgtg ggttttaaat taaaaagcta
      781 acgttacccc aaaagtgcta gtacaataat gctgttcatt aatttcgttg gtttcattcc
      841 gccatcctta cctccttgaa ttagtatgtg ttgatccggg aaacactgtc acaattacac
      901 cgtctatatt gtttcctgat atctcataac gaagattagt cggcacatga atggtggtat
      961 ttttagtaac aggataataa aagatctcat atttttcccc atttacacta acagaaatgg
     1021 ttttttcttc ttttaggtaa tccatatatt cctcgagaac gaaattcttt tctttcataa
     1081 tcgcactatg tggtaaacca acatagcgaa tatgccatgg ttcatattga attcctgtta
     1141 actctgtttt gtcctctgga taacgtaaaa tgaacccgta tttccaagca ttttcttcta
     1201 tccactttcc ttcaggggct cgttccattt tcgtcaagct tgatcctaca tctagtgata
     1261 aacctgaatt atgctcacta taacctgctg gtaaggcata ctcagccccc atttcttggt
     1321 aaagcacact ttgctcatca aagtctcgat agccactatt aataataaaa tgactaacgc
     1381 caccctttac agcatcattg accatctctg aaaatttttg tgctatttct tttgacatat
     1441 aaatattact atcaagcaac ccgtatccat ttattaattc gtcatgttta gataaattca
     1501 cgatatctga cttcacactt tcttggcgaa caggatattt actattgatt aatagcagat
     1561 ttccttgata aacctgttct tctgtaattg ttttctcttg ggtattttca gaagtcccac
     1621 tattttctaa atgttctttg ggattttgat cataattttg aaattcgact ttttcctgag
     1681 aaaacagtgc ttcattaacg tagtcataac ctaagtatat taagaataac aataacaata
     1741 aaaaaaacaa cttcttcatt ttcagtctcc tccttaacta tatagttgga agtatgaaat
     1801 atttctagaa tcttcccctt aaacggcaca atctcgtttg agattgtgcc gttttgcccc
     1861 gtaaattaca gtcaattatt tcgccctact ggatttacta ttatcaccaa tgtagatgaa
     1921 ttttcataag tga
//
LOCUS       DACGMI010000139         1928 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.150, whole genome shotgun sequence.
ACCESSION   DACGMI010000139 DACGMI010000000
VERSION     DACGMI010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.150"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            198..1163
                     /locus_tag="IXT46_002964"
     CDS             198..1163
                     /locus_tag="IXT46_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAQ4948826.1"
                     /translation="MSKKGIIVNEWEKLNRISNRRLNVQNLNTPLKLQWSIDRITIVG
                     KLKENIYYHTPNDVLILNFEQLMQLNEGNGFVKSVGKNGWQIVDQYEENIAYIELLQF
                     HEGKARIDFNPNKIGQFLASSMKNFIHDLFLEPHFSRADIACDMVNVPDEFIMQYRVV
                     DPVSFKPIYGRSGKLESAYWGSRASERQIRLYNKKLEQETKRKVVPKEVETWWRLEMQ
                     LRRGKATDWHNMVQESLNSFASLHFLPIDTTPTDRIMLAGLMSDQNFWSLLSRNSKYK
                     YRELLKEESQNDELTNHLRETFAESADNLKQELDTWLLGLDVTEK"
     gene            1363..1566
                     /locus_tag="IXT46_002965"
     CDS             1363..1566
                     /locus_tag="IXT46_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948827.1"
                     /translation="MSQLGKCYSLSKSNRKVYTLFISDSAKEGFNLGFSISFKKGTKN
                     TSISHNNRELTDSQKINSLSGRK"
BASE COUNT          630 a          294 c          438 g          566 t
ORIGIN      
        1 aaaaaaatag tcgagcagtg ttgacgcact ctcgaccttt acggaaacta cttcacctag
       61 ttccgtaact caagttcatt atacgaatat ttttaggttt cttcaagcta gagatttttg
      121 gatgtggatt tttagagtta cgtgaactct ggaaattctt tccaagaatc tcttttttcg
      181 ttgaggagga gctatttttg agtaaaaaag gcataatcgt aaatgagtgg gaaaaactta
      241 accgtatttc taacaggcgg ttaaatgttc aaaatttgaa caccccccta aaattacagt
      301 ggtcaatcga ccgaattacc attgttggaa aattgaaaga aaatatttat tatcacacac
      361 caaatgatgt cttgatttta aattttgagc aattgatgca attgaatgag gggaatgggt
      421 ttgtcaaatc agttggtaaa aatggctggc aaattgtcga ccaatacgaa gaaaatatcg
      481 cgtatattga gctcttgcaa tttcatgaag ggaaagcacg aattgatttt aatcccaata
      541 aaattggtca gtttttagcc agttcgatga aaaatttcat tcatgatttg tttttagaac
      601 cccatttttc gcgggcagat atcgcttgcg atatggttaa tgttccggat gagtttatta
      661 tgcaatatcg tgtggttgac ccggtatcgt tcaaaccgat ttacgggcgt tctggaaaac
      721 tagaatcagc ttattggggt agccgtgcca gcgaacgaca aattcggcta tacaataaaa
      781 aattggaaca agaaaccaaa cgaaaagttg taccaaagga agttgagact tggtggcggt
      841 tagaaatgca actacggcgt ggcaaggcaa ccgattggca taatatggtt caagaaagtt
      901 tgaatagttt tgcgagcctg cattttttgc cgattgatac aacacctaca gatagaataa
      961 tgctcgctgg tttaatgtct gatcaaaatt tctggtctct tttgtcgagg aattcaaaat
     1021 ataaatatcg ggaattgctg aaagaagaaa gtcaaaatga tgaattgacg aatcatttgc
     1081 gagaaacgtt tgcagaatcg gcagacaatt tgaaacaaga attagacacg tggcttttgg
     1141 gtttggacgt gacagagaag tgataccgaa taagaaaagt cagatgagtg agagtaaatt
     1201 tacgtcaatg tttaatgacg tgagtttacg ataagcgatt attttgcgtg aagcaaaata
     1261 aagcgtaaaa ggagttgaga gcgtgacacg ctttcggctc cttttttcgt tgtcacttgt
     1321 gacagcgaat accctcggag agcatttgga attgtgacag ccatgtcaca attaggaaaa
     1381 tgttactctt tgtcaaagag taacagaaag gtttacactc tttttattag cgacagcgcg
     1441 aaggaggggt ttaacttggg gtttagtatt tcgttcaaaa agggaacaaa aaatacaagc
     1501 atttctcata ataatcgtga gttaactgat agccaaaaaa ttaatagttt gtctggtaga
     1561 aaataattag cagatttaca agtgggaaat aaaaagctga aagaagaaaa ttgcatttca
     1621 aactacattt tctacaataa ctctaaaatg gcatattttg cgttctgagc ggttttagcg
     1681 tttatttcgt ttagttatcg gcacaatcgg tgaaacacgt tagaggagcg aaaatggagc
     1741 ctgtaaggcg actggtagcg gaacggtcgt gttagattgt gtagccgata gctgaacgaa
     1801 ataaatgctg gcagcgccat tctatttcgg caggaggagg ctcaaggggt tcggggaatg
     1861 aaattccctg aggtcttttt attttttcta gaggagtgct ataatcaaag aaaatgagaa
     1921 aaaagagt
//
LOCUS       DACGMI010000140         1654 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.151, whole genome shotgun sequence.
ACCESSION   DACGMI010000140 DACGMI010000000
VERSION     DACGMI010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.151"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            78..193
                     /gene="rrf"
                     /locus_tag="IXT46_002966"
     rRNA            78..193
                     /gene="rrf"
                     /locus_tag="IXT46_002966"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            203..276
                     /locus_tag="IXT46_002967"
     tRNA            203..276
                     /locus_tag="IXT46_002967"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:237..239,aa:Asn,seq:gtt)
     gene            316..405
                     /locus_tag="IXT46_002968"
     tRNA            316..405
                     /locus_tag="IXT46_002968"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:350..352,aa:Ser,seq:gga)
     gene            420..491
                     /locus_tag="IXT46_002969"
     tRNA            420..491
                     /locus_tag="IXT46_002969"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:453..455,aa:Glu,seq:ttc)
     gene            507..579
                     /locus_tag="IXT46_002970"
     tRNA            507..579
                     /locus_tag="IXT46_002970"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:540..542,aa:Val,seq:tac)
     gene            589..661
                     /locus_tag="IXT46_002971"
     tRNA            589..661
                     /locus_tag="IXT46_002971"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:622..624,aa:Asp,seq:gtc)
     gene            697..772
                     /locus_tag="IXT46_002972"
     tRNA            697..772
                     /locus_tag="IXT46_002972"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:730..732,aa:Phe,seq:gaa)
     gene            774..854
                     /locus_tag="IXT46_002973"
     tRNA            774..854
                     /locus_tag="IXT46_002973"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:808..810,aa:Tyr,seq:gta)
     gene            861..934
                     /locus_tag="IXT46_002974"
     tRNA            861..934
                     /locus_tag="IXT46_002974"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:893..895,aa:Trp,seq:cca)
     gene            937..1009
                     /locus_tag="IXT46_002975"
     tRNA            937..1009
                     /locus_tag="IXT46_002975"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:970..972,aa:His,seq:gtg)
     gene            1021..1092
                     /locus_tag="IXT46_002976"
     tRNA            1021..1092
                     /locus_tag="IXT46_002976"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1053..1055,aa:Gln,seq:ttg)
     gene            1138..1208
                     /locus_tag="IXT46_002977"
     tRNA            1138..1208
                     /locus_tag="IXT46_002977"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1170..1172,aa:Cys,seq:gca)
     gene            1229..1313
                     /locus_tag="IXT46_002978"
     tRNA            1229..1313
                     /locus_tag="IXT46_002978"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1263..1265,aa:Leu,seq:caa)
     gene            1375..1447
                     /locus_tag="IXT46_002979"
     tRNA            1375..1447
                     /locus_tag="IXT46_002979"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1408..1410,aa:His,seq:gtg)
     gene            1457..1528
                     /locus_tag="IXT46_002980"
     tRNA            1457..1528
                     /locus_tag="IXT46_002980"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1489..1491,aa:Gln,seq:ttg)
     gene            1546..1630
                     /locus_tag="IXT46_002981"
     tRNA            1546..1630
                     /locus_tag="IXT46_002981"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1580..1582,aa:Leu,seq:caa)
BASE COUNT          388 a          376 c          431 g          459 t
ORIGIN      
        1 actcggaaaa aaacttatgt gacttcaaat ccagttttga gtgaacaaaa tttactcaat
       61 aaaagataac accacagtgt ggtggcgata gcgagaagga tacacctgta accatgccga
      121 acacagaagt taagcttctt agcgccgatt gtagtgaggg gttgcccctt gtgagagtag
      181 gacgtcgcca cgctgatgtt attccggcat agctcagttg gtagtagcgc atgactgtta
      241 atcatgatgt cgtaggttcg agtcctactg ccggagttct cattttgaga aagagtattg
      301 agcttctttc actctggaga gttgtccgag aggccgaagg agcatgattg gaaatcatgt
      361 agatggtgcc aaactgtctc aagggttcga atcccttact ctccgtagca aatttacctg
      421 gcccgttggt caagcggtta agacaccgcc ctttcacggc ggtaacacgg gttcgaatcc
      481 cgtacgggtc attttaattg aatgttggag gtttagctca gctgggagag catctgcctt
      541 acaagcagag ggtcagcggt tcgatcccgt taacctccat aatgaactgg ttccgtggtg
      601 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
      661 gtcgttcttg ttattcaatt aataatttta aaatatggcg cggtagctca gttggtagag
      721 caacggattg aagctccgtg tgtcggcagt tcgattctgt cccgcgccac catggaggag
      781 tagcgaagtg gctaaacgcg acggactgta aatccgttcc ttagggttca gtggttcgaa
      841 tccactctcc tccattttat aggggcatag tttaaaggta gaacagcggt ctccaaaacc
      901 gttagtgtgg gttcaattcc tgctgcccct gccatggcga atgtggcgaa gtggttaacg
      961 caccggattg tggctccggc attcgtgggt tcgattccca tcattcgccc tttttattct
     1021 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
     1081 cagctacccc agtttctata atttattctt tattttatag attgataata gtataatggc
     1141 ggtatagcca agtggtaagg cagaggtctg caaaaccttc atcaccggtt caaatccggt
     1201 taccgcctta gtactaataa atcaacttgc cggcgtggcg gaattggcag acgcgctgga
     1261 ctcaaaatcc agtgcccgtt gagggcgtgc cggttcgacc ccggccgccg gtattgacta
     1321 agatgtcttc atcttagttt tttattgaga aattaaataa catcttttat gatggcgaat
     1381 gtggcgaagt ggttaacgca ccggattgtg gctccggcat tcgtgggttc gattcccatc
     1441 attcgccctt tattcttggg gtatagccaa gcggtaaggc aagggacttt gactccctca
     1501 tgcgttggtt cgaatccagc taccccagtt attattttta aatttgccgg cgtggcggaa
     1561 ttggcagacg cgctggactc aaaatccagt gtccgttgag gacgtgccgc ttcgaccccg
     1621 gccgccggta taattatcaa tatagcaact ttct
//
LOCUS       DACGMI010000141         1636 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.152, whole genome shotgun sequence.
ACCESSION   DACGMI010000141 DACGMI010000000
VERSION     DACGMI010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.152"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(183..1502)
                     /locus_tag="IXT46_002982"
     CDS             complement(183..1502)
                     /locus_tag="IXT46_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HAQ4948828.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
BASE COUNT          485 a          301 c          325 g          525 t
ORIGIN      
        1 attctttggc acattttatt gaaatatgta tcactaatat ccctatcaac tgattttgac
       61 taaaaagtta cttcaaacat tcactgttca aaaatattga ggaataaatt ttgggtgtaa
      121 ggcattttga gcatacttct ccctggataa cttcccagta aaaaaatcgt tagattgttg
      181 gattagatcc attgactggc tcgcctcagg cgagcaaaga ccctgtagaa ttcattctga
      241 tacacatgat aactagataa tttgagatag actcgtctac ccgtttggac taatttccca
      301 gcaactttca gaaacttcaa tcgaatagaa tgaatggtca ttcccttttg gacttcttca
      361 aagccaatcg ttcttaagaa gttgactaag ttgtaagcta tcaagctgag catcattcgg
      421 acatgattct ccaaaaagcg aggactgtct gttttgtcaa agtaaaagcc agctttcgct
      481 tctttaatga agttctccat tgtgccacgt ttggcataga tagaaaagat ggtatcagga
      541 gaaacatttt ctgatagatt cgtcacgata aattcatgtc gaaagagtag ttcgcccgct
      601 tcacgtgttg agcgtataca cacgcgacga ctttgtgacc aggattgtgc ttgataagtg
      661 gtcgagaagt actgaacttc tcgttcttcc cacttttgat tatcgccata aagtactgat
      721 ttctcagcta tttgacctag tctacgatta ttcttcagtc gaataacata atgactcttt
      781 tttgattcac acgaatcata cacaccaggt gtagcgaacc cgctgtctcc acgaaccaag
      841 atgtcagtgt ttggtagaga gtgattatag tgctctaata aaggtgtgag aaactccttt
      901 acgccttttg atgtatattg atttcctgaa cgtagttcag cttttaagaa gtcaccagtc
      961 aatccgtcaa aagctaccaa tggatggtaa ccataggttt ggtagtgtgt attataattc
     1021 gtttgttctt ggtgaccaaa tgtatctgaa tgggtcgaat ctaaatcaat gattaattcc
     1081 gtatcattac ggatgaggcg tgctttatcg ataagttctt ggttcaaagc ttgaagttca
     1141 tggatattct cctcagatag tcgatctaaa aatcgggaaa gtgaagattg agaagcgagt
     1201 tctttcctat ctaaaacagc tttaaacaca ggatcttgtc tcaggagatt agctgcagaa
     1261 tcagctgagt aaccagcaat taattgcata atgaactgct caagtatgga taagttgtca
     1321 tgagtaaaat acgctcgttc gtcttcaatg tgaatgtgtt gcttagccag ttcagaaaaa
     1381 ccaaagatgt tcatcagctc tttcactagg acgagacccg aatcactcga taattgacca
     1441 cctgtatgag aaatagtgat atttgaattg aattttactt ggtttttgtg taagctagtc
     1501 atgaaaagaa ctcctttctt ttggttggtt tagtcacttt aaccatagca gaaaggggtt
     1561 cttttttcat cacttaacgg gtgaagatga aaaagtaatt gtaagctgcc gtgaggcagt
     1621 ttcacatggt tttaat
//
LOCUS       DACGMI010000142         1627 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.153, whole genome shotgun sequence.
ACCESSION   DACGMI010000142 DACGMI010000000
VERSION     DACGMI010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.153"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..132)
                     /locus_tag="IXT46_002983"
     CDS             complement(<1..132)
                     /locus_tag="IXT46_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4948829.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
     gene            542..1516
                     /locus_tag="IXT46_002984"
     CDS             542..1516
                     /locus_tag="IXT46_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAQ4948830.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          578 a          230 c          285 g          534 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaaatgata ttttacgagg aggaataaac
      541 tatgtgtacg tctattactt atgtaacaag tgatcattat tttggaagga attttgatta
      601 tgaaatatct tacaatgaag tagttactgt tactccaaga aattataagt tgaattttcg
      661 aaaggtaaat gatttggata ctcattatgc aatgattggt attgccgctg gtatagctga
      721 ctaccctctt tattacgatg cgacaaatga aaaaggattg agtatggctg ggctaaattt
      781 ttctgggtat gctgattata aagaaataca agaagggaaa gacaatgtat ctccttttga
      841 atttattcct tggattttag gacaatgctc aacagtagga gaaactaaaa aattgttaaa
      901 aaatatcaat ttagcaaata taaattatag tgatgaactt cctttatccc ctttacattg
      961 gctattagct gataaagaaa aatcaattgt cattgaaagt atgaaagatg gacttcatat
     1021 atatgataac cctgtgggcg ttcttaccaa taatccttca tttgactatc aattatttaa
     1081 tttaaacaat tatcgtgtct tatcgagtga aactcctaaa aataattttt caaatcaaat
     1141 aagtttgaat gcctatagcc gcggtatggg agggataggc ttgcctggag atttatcctc
     1201 agtatctcgt tttgttaaag cgacttttac gaagctgaat tctgtatctg gagattcaga
     1261 gtcagaaagt attagtcaat ttttccatat cttaggttca gtagaacaac aaaaaggttt
     1321 gtgtgatgtt ggtgatggaa aatatgaata tacaatttat tcttcttgtt gcaatgttga
     1381 caaaggaatc tattattatc gaacatatga agacagtcaa attactgcaa ttgatatgaa
     1441 taaagaagac ttagatagtc ataagttaat tagttatcca attatagaaa aacaacaaat
     1501 taaatatata aattagttaa tgtgttgtga ttgattattt aatatagata taatacaaaa
     1561 aggcaaagat attttcaaaa cattttttct tgatgtgata tccttgtctt ttttgtaatg
     1621 tttttaa
//
LOCUS       DACGMI010000143         1607 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.154, whole genome shotgun sequence.
ACCESSION   DACGMI010000143 DACGMI010000000
VERSION     DACGMI010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.154"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(292..435)
                     /locus_tag="IXT46_002985"
     CDS             complement(292..435)
                     /locus_tag="IXT46_002985"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948831.1"
                     /translation="MEKEAFDLHVLGTPPAFVLSQDQTLIKSSNNLAIVKLNLFASIL
                     LAC"
     gene            355..>1607
                     /locus_tag="IXT46_002986"
     rRNA            355..>1607
                     /locus_tag="IXT46_002986"
                     /product="16S ribosomal RNA"
BASE COUNT          470 a          331 c          444 g          362 t
ORIGIN      
        1 taataacgaa gtcgtttgga tgagatagct aataaagctt gattttatcg aaaaaaactt
       61 cgaaaaagtt attgacaaat aacaataaag atgctatgat aatcaagtcg ctgctaatga
      121 gtggcaaaga cgtttagaaa aaataaacaa agaagttgtt gacattctct tctgaatctg
      181 ataagattaa agagttgtta aaacaaaaag attagacctt tgaaaactga acaaagtaag
      241 acaaaccaaa tgtgtagggc gtcttgattc aattcaagac aacaaacatt tttaacaagc
      301 aagcaatatg ctagcaaaca aattgagctt aacaatcgca agattgttcg aactttttat
      361 gagagtttga tcctggctca ggacgaacgc tggcggcgtg cctaatacat gcaagtcgaa
      421 cgcttctttt tccaccggag cttgctccac cggaaaaaga ggagtggcga acgggtgagt
      481 aacacgtggg taacctgccc atcagaaggg gataacactt ggaaacaggt gctaataccg
      541 tataacaatc aaaaccgcat ggttttgatt tgaaaggcgc tttcgggtgt cgctgatgga
      601 tggacccgcg gtgcattagc tagttggtga ggtaacggct caccaaggcc acgatgcata
      661 gccgacctga gagggtgatc ggccacattg ggactgagac acggcccaaa ctcctacggg
      721 aggcagcagt agggaatctt cggcaatgga cgaaagtctg accgagcaac gccgcgtgag
      781 tgaagaaggt tttcggatcg taaaactctg ttgttagaga agaacaagga tgagagtaac
      841 tgttcatccc ttgacggtat ctaaccagaa agccacggct aactacgtgc cagcagccgc
      901 ggtaatacgt aggtggcaag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg
      961 tttcttaagt ctgatgtgaa agcccccggc tcaaccgggg agggtcattg gaaactggga
     1021 gacttgagtg cagaagagga gagtggaatt ccatgtgtag cggtgaaatg cgtagatata
     1081 tggaggaaca ccagtggcga aggcggctct ctggtctgta actgacgctg aggctcgaaa
     1141 gcgtggggag caaacaggat tagataccct ggtagtccac gccgtaaacg atgagtgcta
     1201 agtgttggag ggtttccgcc cttcagtgct gcagctaacg cattaagcac tccgcctggg
     1261 gagtacgacc gcaaggttga aactcaaagg aattgacggg ggcccgcaca agcggtggag
     1321 catgtggttt aattcgaagc aacgcgaaga accttaccag gtcttgacat cctttgacca
     1381 ctctagagat agagcttccc cttcgggggc aaagtgacag gtggtgcatg gttgtcgtca
     1441 gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccctta ttgttagttg
     1501 ccatcattca gttgggcact ctagcaagac tgccggtgac aaaccggagg aaggtgggga
     1561 tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac acgtgct
//
LOCUS       DACGMI010000144         1586 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.155, whole genome shotgun sequence.
ACCESSION   DACGMI010000144 DACGMI010000000
VERSION     DACGMI010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.155"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            295..1482
                     /locus_tag="IXT46_002987"
     CDS             295..1482
                     /locus_tag="IXT46_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4948832.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
BASE COUNT          467 a          296 c          318 g          505 t
ORIGIN      
        1 gggttttaac cttccggttt tgattggata accctatgaa ccatcgttat tttaatttgg
       61 tattaactca tttcttttga gataatatat ttattggatt gagaggctaa gccgttcccc
      121 ccttgggcca ttgaacccgc actcgagaga ctggctcctc tctctgataa gtggattgcg
      181 tatgagttag atgttgaaag tccttacttt actccgtatc tcgtacaagg tagtgacgct
      241 tttcagttga gtggatttca atccaaaatt ctttttttga aaggtcagat atacatgtac
      301 tttttaggca ttgatatcgg taaacgcact cacgttgctt ctatcatgaa cgaggaagga
      361 aaggtattac taaaaggttt ttcatttcct aacaccactg aaggagcaga gtcattaatt
      421 gagcgaatgg tcgactattc cggagcaccc agtgactttg ttatagggat ggaagccacg
      481 gggcactatt ggctgtccat cttttcatac cttcacgaat cagattattt gattcacgtt
      541 gtgaatcccc ttcaaacaga cggatggcgt aaaggtacag aaatacggaa acgaaaaaac
      601 gatattattg attctgtttt gattgctgac ttaatgcgct atggctcatt tgtcgaaacg
      661 gtcttatccg atgaaaatgt tttttctttg aaacaacttt ctcgttaccg aacttattta
      721 gtaggtacag cgagcgactt caaaagaaaa attatagccg tattggatca agtctttcca
      781 gaatacgcga cgatttttac caagcagggc gttttcggaa aagcttctaa agagttattg
      841 ctggcgttta gtgccccgat cgacttagaa aacatttcct cagaaacttt ggcccaatac
      901 ttagctgagt taagcaggaa ccgaatcaag gcagaaaaag cggaccaatt gaagcaagca
      961 gcttctaact cctttggagt aaaatttgct caagaagcgt tcaccttcca actacgttca
     1021 atgattgaac aattaaaatt cattgaaagc caaataaagg aaacggaaag agaaatcaag
     1081 cacataatgg acactttaaa ttctgttatt ctcacaattc ctggaattgg tcctataaac
     1141 ggtgcgacta ttcttggtga gatcggagat attcaaaaat tttctaaccc gaaaaaactc
     1201 gttgcttacg ctgggataga cgcttccgtg acacaatcag ggcaatatga ggcaacgcat
     1261 aatgttatga gtaaacgagg gtctccatat ttgcgaaaag ccttgttttc ggcggcttta
     1321 gtagcttctc aatgtgatcc tgtttttagt gcgttttacc agaaaaaagt ttccgaagga
     1381 aaacatcatc taactgcctt aggtgcggtt tctcgtaagc tttgttacgt gattcatgct
     1441 attttgacta aaaacgagcc ttatataatt gtttctgatt agctattgaa cattcaaaaa
     1501 aactaatggt aagaagctta tttgttgtac ccttttttcg gaattatctg ttataaaata
     1561 ttttttgatt tggctaattt ttactt
//
LOCUS       DACGMI010000145         1531 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.156, whole genome shotgun sequence.
ACCESSION   DACGMI010000145 DACGMI010000000
VERSION     DACGMI010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.156"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            289..696
                     /locus_tag="IXT46_002988"
     CDS             289..696
                     /locus_tag="IXT46_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948833.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            710..1111
                     /locus_tag="IXT46_002989"
     CDS             710..1111
                     /locus_tag="IXT46_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948834.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1113..1484
                     /locus_tag="IXT46_002990"
     CDS             1113..1484
                     /locus_tag="IXT46_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948835.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
BASE COUNT          579 a          186 c          265 g          501 t
ORIGIN      
        1 tttgagggga agtacatata gttgttgata tagttgctaa tattgttagc taatttgtta
       61 gtaaaactgt atacgaattt agatagtaaa aaaacagttt gttccttata tagaggcact
      121 tttactactg attaaatgtc agatatgctt acaaatatac ttataaatat gcttacaaaa
      181 ttagctaata tttccgttga caaagctttg ttactattgt taaactaaat tgactagcaa
      241 aagtgaaaca taaatttatt aaataaatgt aaaaattagg agaaatcaat gtcttataga
      301 gtacaattaa taatttcaga agatgtagaa agtcagcaat ttggcactaa tgttattaat
      361 aaagtaatta atccagctct ttctattaat gcgcctttaa ttcctactgc tttatcattt
      421 tctgtaacag ctgtggtgtc tgagatagag gatacagaaa agataaaaat agtagaaatt
      481 gaagttttaa acaagaatga aaaacaaatt ttttctacgg gtgaagtatc ggtaagcttg
      541 cctcctcaag ttaacgatat aaactttaat ataaacgcca gaaatgtctt ggttgaagaa
      601 gcaggagagc attatgctgt tgttaaattt aatggaactg agattggaag gcaaatcttt
      661 gatatcaagg tcaacaaacc agtggaaaaa aattaaggag acgatacgga tgcttgatat
      721 agtaccatca aatacacatc ggagtggtag cttaataaat tttgctgcga tttttgcttg
      781 cgcatcggta attctagcat ctccagttgt tgtggatgca agttctactc cgaaaactaa
      841 aaatgataat caacttgtaa ttactacaaa aaatgagatt aacacaattt caagtaatga
      901 tggcaaaatt tttgatgtga taaatacggt tttaaaaaga aaagctgaaa tcaatataaa
      961 atatgatgaa gatttaaact tgtatttctt tgttatcaaa acaacatctg aattgttttc
     1021 ctcagattac gatgttttgg atactctcga taatgtatta tctgactata aatatatggg
     1081 gaaatctgta gtagcaactt tgggggaata aaatgtttga ctttaatgaa tatttatcta
     1141 tttccaaaca aattgaatca gatgataaat ataattctaa agaatcttat agaagaactg
     1201 ctgtttcaag agcatactac agtgctttta aaaaatctga tgagtatttg aaagaaaatt
     1261 atgatattat ttataatgga agtagcggaa aaggaagcca ccaaaccgtt tggaatttgt
     1321 tttcaacagt taaggaattg aataccttag gaatacataa tagtgggtat agaatgttag
     1381 agaaaagaaa atgtgctgac tatattccta atgaaaccat tacgaaaaca gatatggcgc
     1441 tgatgaatcg agaagcagaa aaaataataa acaaactcac ctaatgaatt tcaagcgagt
     1501 ttgtttgtta tttttttatt taatctttgt a
//
LOCUS       DACGMI010000146         1424 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.158, whole genome shotgun sequence.
ACCESSION   DACGMI010000146 DACGMI010000000
VERSION     DACGMI010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.158"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(150..1337)
                     /locus_tag="IXT46_002991"
     CDS             complement(150..1337)
                     /locus_tag="IXT46_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAQ4948836.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DACGMI010000147         1416 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.159, whole genome shotgun sequence.
ACCESSION   DACGMI010000147 DACGMI010000000
VERSION     DACGMI010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.159"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            107..1408
                     /locus_tag="IXT46_002992"
     CDS             107..1408
                     /locus_tag="IXT46_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAQ4948837.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          467 a          285 c          260 g          404 t
ORIGIN      
        1 ctgatagaaa atcattctat cggtcccttt tgagcatgaa aaaacaaaac atacagaagc
       61 tccgttagaa ttgaatcacc acaacacaat caaaggagcg ttctgtatgc ctgatcttca
      121 tcatatcaaa ctactacttg gaatcaaaga taaaaacatt ttcatcacaa atgtggaatc
      181 gaagagcatt aagaatatca agagtcttgt tgtttctgcg acgttaagta aagaaattcg
      241 tcgctgtcct ttgtgtaaac agatgaatca tgaaggcatg atcgttaaga acggaaagaa
      301 aaaatcgctc attcaactta ataaatgtgc gaaccaactg acttatcttg ctttagcgaa
      361 acaacgctac cactgtcgtg gctgccacac ctattttacg gcgaatacct acattgtcga
      421 tagaaactgc tttatcgcta aacaagtgcg ctataaaatt ttagaagagc taactgaaaa
      481 acaagcaatg acgacaattg ctaagcattg cggcgtttct tggtcgaccg tttctcggac
      541 actcgcttct ctgatcccca tgacaaaagt aaaaagaaat tggttaccgc gttgtttatt
      601 aatggatgaa tttcgttcac tgaaaaatca agtcggtccc tactcctttt cttgtatgga
      661 tggcgatact ggaaaattac tggatattct tccttcacgg aagaaaaagg ctctcgtttc
      721 ttattttatg caatttgaac gacgcgcacg attgaaggta aaggtcatcg tgacggacat
      781 gaatgtttct tatgcctctc tgataaagga atgttttcca aaggcaaaac tcgttgtgga
      841 tcgttttcac attgtcaaac atctcattcg taaatttgag gatattcgcg tacgaatcat
      901 gaaaagcttt gatcgaaacg atccaacaca agccaaatat tatcgacaat taaaggcgtt
      961 gtctcggctt ctgatcaaac gacaggacaa gcttgtttat gacaaatgga ccaaatggcg
     1021 caattttggt tgggcgtatc tcaccgaaag tgaagtggtg gatcgtctgc tttcgatctc
     1081 tgacgaatta cgaatcgcct atttttacta tcaagaaatt cttcaagcgt ttcacgacaa
     1141 agaggcggac actttcttta aacttgtaag aacgatgccc aattccgttc caaaagaact
     1201 gcattctata aaaaaagctt ttataaacta tgaatccggc attcgtttag ccctcgaatt
     1261 gccttattca aatgccaaaa tagaaaatct gcatacccac atcaaagcat tgaaacgagt
     1321 cgcttatggc tttcgaagct ttcggaaaat gaagaccaga attttcttac taaataatct
     1381 gattacctat gaatcaaaaa acatctaaag tagaaa
//
LOCUS       DACGMI010000148         1389 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.160, whole genome shotgun sequence.
ACCESSION   DACGMI010000148 DACGMI010000000
VERSION     DACGMI010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.160"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            78..875
                     /locus_tag="IXT46_002993"
     CDS             78..875
                     /locus_tag="IXT46_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948838.1"
                     /translation="MVVSKLPRNEDYLTNYDGYVVTTEHFDLANPVTKVDDIPDYEMY
                     SQTIDSLNKRFGNRVLKGIEIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDD
                     EVKDMDPAIVIPQYFAQLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPIL
                     DQVIKNKLAFELNAKSAYLYDNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFD
                     DLFALLKAKGVTELAIYQKGKRIMVPLPVQKNVLSIKSEDVFLDFFF"
     gene            complement(858..1355)
                     /locus_tag="IXT46_002994"
     CDS             complement(858..1355)
                     /locus_tag="IXT46_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4948839.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT          437 a          243 c          235 g          474 t
ORIGIN      
        1 taaaacccgt ggtgctagtt aattttttcc tagaggaaaa tgtctaaaca tgttggtaaa
       61 tcaacaaaaa aacgcatata gtagtctcaa aactcccaag aaatgaggac tatttaacaa
      121 actacgatgg ttacgtcgtg acaactgaac attttgactt agccaatcct gttactaaag
      181 tcgatgatat ccccgattat gaaatgtaca gtcaaacaat cgatagctta aataagcgtt
      241 ttggcaatcg tgttttaaaa ggcatcgaaa tcggttacat cgcttctgaa aaggatcgga
      301 tcatcgacta tttagccgat aaagattacg atttaaaatt actcagtgtg catcataatg
      361 gtcaatttga ttatttagat gacgaagtca aagatatgga tcctgctatt gtgattcctc
      421 agtattttgc acaactttca gaagcactag ttgttataga agcagatgtc tttgctcatt
      481 ttgactatgg ttttcgggta tttggtctat ccgttgctga atttaaacaa tatgaagcgc
      541 agtttttacc gattctagat caagtaatta aaaataaatt ggcattcgaa ttaaatgcta
      601 agagcgctta cttgtatgac aatttagcgt tatatgaata tgtcatcgat ttatatcttt
      661 cacgtggtgg taccttgttt agtgttggat cagatgggca ttaccttgaa catttccgtt
      721 tccatttcga tgatcttttt gctctgttaa aagcaaaagg tgtgacggaa ttagcgattt
      781 atcaaaaagg aaagcgaatt atggttccat taccagtcca aaaaaacgtc ctcagcatca
      841 aaagtgagga cgttttttta gatttctttt tctaaaatcg gacaaatacg atcttgtttt
      901 cctaaaggaa aatgtttgat cccgattttt ttaaatccat gacgttcata aaaacgaata
      961 cctgcatgat ttttttcata aacagtcaaa cgtaaataac gtttttgttt cgttttagca
     1021 taacgattcg cttcatcgag taaccgttgc cctaaccctt tgttttgata atctttgagc
     1081 agatagagcc gttgaatctc tatagcatct ttttcatcat tgactttcat ataaccaatg
     1141 agtatttgat gatccttaat accaataaat ttactggttg actgtgccaa ttctactgcc
     1201 aatatttcag ttgtcaattg tgtctgtaaa tatccttgca tatcaagtgg atctgcgcca
     1261 tcgataaacg attcataaaa actgacaaca cttacaactt gtaaagcatc tagatcatca
     1321 taatctaaat acgctagtgt gatttgattg ttcatctaac tcctcctttt gacatagtat
     1381 actataaat
//
LOCUS       DACGMI010000149         1355 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.161, whole genome shotgun sequence.
ACCESSION   DACGMI010000149 DACGMI010000000
VERSION     DACGMI010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.161"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..>1355
                     /locus_tag="IXT46_002995"
     rRNA            <1..>1355
                     /locus_tag="IXT46_002995"
                     /product="23S ribosomal RNA"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DACGMI010000150         1343 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.162, whole genome shotgun sequence.
ACCESSION   DACGMI010000150 DACGMI010000000
VERSION     DACGMI010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.162"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(69..1208)
                     /locus_tag="IXT46_002996"
     CDS             complement(69..1208)
                     /locus_tag="IXT46_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAQ4948840.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT          351 a          289 c          249 g          454 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgtttatta
       61 aaaaaatctt acgctaagta ggataaaata attccttgat atttttcgat catatccaaa
      121 taattatcga tttcaacata ctcatctact tgatgaggca aagtaacgac accaggccca
      181 aagacgacaa agtcgaagga atggttagct ttcgtaaatt cggctgcatc cgttgttgct
      241 gccgctccaa ctaaaggtaa tggctggctg aattgttgct gaatgcaatg aatcaaagga
      301 gaatctggat cagctttgac aggtattttg ttgtaatcga tcatcaattc caaatgatag
      361 tctgtctctt gattcaattc attgacgatt gattgcagca atgcaatgat tttatcattt
      421 gggtattctg gaatcgatcg aatgttccct tggagctgcg catggcttgg gatgctgttg
      481 acttgattcc cgccactgat caatgtaaca ttatggattg tttttcctag gacaggattc
      541 tcgattgttt cagcgaggtg attcatttca gcatttgctt tcgtaatgaa ttcatttagg
      601 tgattgattg cattataacc ttggtctggc atagagctat gcgcttcttt tccgtgcgag
      661 gtgactgtat agttgattga tcccatgtgc gtatacatca aactgtaatt ggttggctct
      721 ccgatgatca aggcatctaa gtcatctaca tagcctgctt tcgtgagctg ttccccacct
      781 agttcaccca cttcttctcc gacagtggct aataatttga ctgttccgtt aaatggtttt
      841 cctgactctt tcagttcgat catggcaatc accattgctg ccaagccact cttcatatct
      901 gtagcaccac gtccgtacaa acggttccca tggatttctg ctgcaaaggg tgcataggtc
      961 caagacgatt catcaccagc cgccacgaca tccatatgcc cagataggcc taacactttt
     1021 cctgattggc ccttttggta acgagcaatc aaattatctc taccatctct gtaagaaaca
     1081 atctctcctg ttatgtcatg ctttgccaaa agcttattca aataggctgc tacttcacct
     1141 tcgtttccat tcactgattt aattcggata atctcttgta aaatcgcgat tttttcttct
     1201 tttttcatct aatcctctcc cttgccattt ctttttattg tatttgagtg tgctcgaatt
     1261 ttcaaatagg agcaaccaaa gtaaaaatga agaaagagag ccactttatg aaaaatatgc
     1321 tgctacttcc ctcctatttt att
//
LOCUS       DACGMI010000151         1246 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.163, whole genome shotgun sequence.
ACCESSION   DACGMI010000151 DACGMI010000000
VERSION     DACGMI010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.163"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            200..742
                     /locus_tag="IXT46_002997"
     CDS             200..742
                     /locus_tag="IXT46_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948841.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            832..>1246
                     /locus_tag="IXT46_002998"
     CDS             832..>1246
                     /locus_tag="IXT46_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HAQ4948842.1"
                     /translation="MDELKRTEIQIIDKKERPKNGFVLSEKTDLENTEAFNKESVKDL
                     RKLPTKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIV
                     GVVTDPVDDNGENKEAIEKSKLIHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DACGMI010000152         1244 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.164, whole genome shotgun sequence.
ACCESSION   DACGMI010000152 DACGMI010000000
VERSION     DACGMI010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.164"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..586)
                     /locus_tag="IXT46_002999"
     CDS             complement(<1..586)
                     /locus_tag="IXT46_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948843.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKIND"
BASE COUNT          428 a          200 c          133 g          483 t
ORIGIN      
        1 tatcattaat tttataaaaa aaattaaatg tttttagcac tgccatataa cattcaaaac
       61 attcttctat agttggttta cttccttgag gagaatgaac caatttatta cgtttttcta
      121 tgaaattttt aatttccttt cttatttctt tcggaaactc aatattaaag taccctttaa
      181 acatgctccc taataatttg tctacagggg gagattgtaa attctcaaat attagagtta
      241 aatcaggttt ctcttgttga taaaattcct ttacccctat ttcacaggct gtaattatcg
      301 aaataaacct atctctagta tttgatatat ttttacttct tttaaggagt ataagagaaa
      361 aggggatact ttcgtgtcca tgcatgtaat taactaattg ttgagcttca gaagttatat
      421 ctctaattat atagttaacg gaattaggaa gtgtctttaa ctctaatgaa atttctatcc
      481 aattactatc ttctaatctg tatatgctcg aagtataatt tgattcgtca gcaagcatcg
      541 ctacatccca aacactgatc ataaaatctt ttaaacgttc aatcatttca gcaatattgc
      601 taaaatcagc taatttttct ttagaataaa aaaaaacatt tatatcagaa tcaataaatt
      661 ctattttttt attactatat cgtcatcatt atcttgacca tttatgttta ttgttccctg
      721 agtggggagt acttctttca aattcaagtt aaatttatat tccattactt ctcctccaat
      781 atataaaaat tacttaactg tatccaaatt taatatgtaa ataaatcatt aatttttagc
      841 taaattctat gagaagttta tttttgttgt ttttgctaat taactaaaac tagtacaaaa
      901 aatttaaaat agattattaa acctattgct tattctattc agtcatatat ataagcgtca
      961 tcctttagta actaacatcc cacactacaa tagtattata acatatctat tcaacttcaa
     1021 attgttgaaa tttaagccat ttatatttac ttttcctcaa ctttagaaat gattttacta
     1081 accttatatc cgtaatacgc gtaacaaaca cattcattaa taacaatcaa cactaagcta
     1141 tattagcttt ttaaatgact agggtaaata aaataaggat caaaaacttt taagtttctg
     1201 acccccgata gatttttcaa gtgtctctat tttgcacagt ctag
//
LOCUS       DACGMI010000153         1195 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.165, whole genome shotgun sequence.
ACCESSION   DACGMI010000153 DACGMI010000000
VERSION     DACGMI010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.165"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..1076
                     /locus_tag="IXT46_003000"
     CDS             <1..1076
                     /locus_tag="IXT46_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4948844.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DACGMI010000154         1188 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.166, whole genome shotgun sequence.
ACCESSION   DACGMI010000154 DACGMI010000000
VERSION     DACGMI010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.166"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            141..398
                     /locus_tag="IXT46_003001"
     CDS             141..398
                     /locus_tag="IXT46_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948845.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1043)
                     /locus_tag="IXT46_003002"
     CDS             complement(630..1043)
                     /locus_tag="IXT46_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HAQ4948846.1"
                     /translation="MDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVLSASIPI
                     LIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEKLLYITK
                     TSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          148 g          436 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatcc
//
LOCUS       DACGMI010000155         1116 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.167, whole genome shotgun sequence.
ACCESSION   DACGMI010000155 DACGMI010000000
VERSION     DACGMI010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.167"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..>1116
                     /locus_tag="IXT46_003003"
     CDS             <1..>1116
                     /locus_tag="IXT46_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAQ4948847.1"
                     /translation="DGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRT
                     HWTAQSYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYL
                     PKQSKKILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGC
                     TNPEEVEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRK
                     AGQKSQAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPP
                     LKEAYPFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIY
                     PYSNGKIEAKNTHIKTMKRVSYGFKSFENMRIRIFLI"
BASE COUNT          380 a          220 c          209 g          307 t
ORIGIN      
        1 tagatggaaa cgggaaagca attatagtga aaaatggaaa aaaggaaacg attgtccgtt
       61 ttgaacaata caatcatatg cctttggtta tgcgcctaaa aaagcaacgc tatacctgta
      121 aaaactgtcg cacccattgg acggctcaaa gttattttgt ccaacccaga cattcaatcg
      181 caaatcatgt tagatataaa attgcttctt tactgactga aaaagtatct ttatctttta
      241 ttgcgaaaag ctgtcaggta tctttgacca ccgttattcg tacattgaaa gagtttaaaa
      301 gctatttacc aaagcaatct aagaagatcc tccccagagt attgatggtt gacgaatttc
      361 gttcgcatgc ttccatagaa gataagatga gctttatttg cgcggatggc gaaacaggaa
      421 aattaataga tgttttgcct acgcgtaaat tacctcgatt aacaagctat ttcttaggtt
      481 gtaccaatcc agaagaagta gaattcttgg tgacagacat gaacgccgcc tacttccagc
      541 tcaccaaacg tgttctgcca aatgcgaaag tcgtgattga tcggtttcat attgtcaaac
      601 acatgaatca agcgttcaat gagttgcgta tccgtgaaat gaatgaactt cgtaaagccg
      661 gacagaaaag ccaggcagaa aaactgaaaa agaactggcg ctttttgcta aaaaatcgtg
      721 caaacatcaa ccattatgaa tacaaaacat ggaaaagttt ccgagcacca aaatacccat
      781 ttcttactga agcaatgatg attgatcgat tgcttgagtt ttctccgccc ctaaaggagg
      841 cgtatccctt ttttcatgaa ttagttgaag cctttcgaga caaagaccct gacttatttt
      901 tctccttatt ggcagaactt cccgaaacgt tagatgacag ctttcgggaa aagcttcaaa
      961 accttctgac ctatgaagaa ggcatcacca acgcaatgat ctatccttat tccaatggaa
     1021 aaatagaagc gaagaatacc cacataaaga caatgaaacg agtatcctac ggatttaaat
     1081 catttgagaa catgagaatt agaatctttt tgatca
//
LOCUS       DACGMI010000156         1062 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.168, whole genome shotgun sequence.
ACCESSION   DACGMI010000156 DACGMI010000000
VERSION     DACGMI010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.168"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(36..992)
                     /locus_tag="IXT46_003004"
     CDS             complement(36..992)
                     /locus_tag="IXT46_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948848.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          178 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca ac
//
LOCUS       DACGMI010000157          989 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.169, whole genome shotgun sequence.
ACCESSION   DACGMI010000157 DACGMI010000000
VERSION     DACGMI010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.169"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            2..>989
                     /locus_tag="IXT46_003005"
     rRNA            2..>989
                     /locus_tag="IXT46_003005"
                     /product="23S ribosomal RNA"
BASE COUNT          307 a          196 c          285 g          201 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgcg taatagctc
//
LOCUS       DACGMI010000158          847 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.170, whole genome shotgun sequence.
ACCESSION   DACGMI010000158 DACGMI010000000
VERSION     DACGMI010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.170"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(37..237)
                     /locus_tag="IXT46_003006"
     CDS             complement(37..237)
                     /locus_tag="IXT46_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4948849.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT          272 a          145 c          134 g          296 t
ORIGIN      
        1 ttttctttcg aaaagacggt taaaagtcaa tttttattaa gctttaacaa tgtttgttgc
       61 ttgagggcca cgttgaccat cttcaacatc gtaagacact gcttggcctt cttctaaagt
      121 tttgaagccg tcaccttgga tagctgaaaa atgtgcaaat acatcatttc catcttcacc
      181 agtgataaag ccaaaacctt tgtctgcgtt gaaccatttt actgtaccgt tattcataaa
      241 taaattcctc ctgatacgta tcaatgtacg ttttttcgtt gcaataaata tttgataggc
      301 aaaaggagtt ttatctatgt agatatatcg ctcaaattac gtttcaaaat agattactca
      361 tttaatatat catgcttttt ctaataacac aaggataatg caatgaaata taaaattcat
      421 tgtcttctat tgtcttcgaa tcgaagaaaa agttgaataa ccgcgattga ttcacttttt
      481 gttttcttgt ttatttgctt ttatctgcaa cttttgactt taaaatttct taactatgaa
      541 aacctttcaa ttggtggtat acttataaat ggaatttcgt tatcaacgcg ttcgttgcct
      601 ttcagcaagt atttaaagaa aggagaatgg ctatgacatt ctataacaaa gatatacaat
      661 atcgagtaac cttggataca gatttgaatc tatttgtcgt ttttgacaaa gaaaatacca
      721 atcatgtagc gacaggtgtt acgatcgaac aagcagtgca agaattaaaa aaatctgcat
      781 aaggagtgga aaccctcata tggacgattc tcgttcttct ctttaaacgc atctactggt
      841 agataac
//
LOCUS       DACGMI010000159          819 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.171, whole genome shotgun sequence.
ACCESSION   DACGMI010000159 DACGMI010000000
VERSION     DACGMI010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.171"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(602..675)
                     /locus_tag="IXT46_003007"
     tRNA            complement(602..675)
                     /locus_tag="IXT46_003007"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(639..641),aa:Ile,seq:cat)
BASE COUNT          282 a          137 c          142 g          258 t
ORIGIN      
        1 gactgacgtg ccggacgcac gtagcgatca tcggcgttat gactatataa agtatacttt
       61 cgttgatcca gaaaggtata aagattaaag taggctacct aaaaaggtag cccggaacga
      121 attttatcac catacttgtg aaaggagata ttttttaagt tagtattaag attgtgtaat
      181 atgatgatat ctatatttta tagtatcagt gctataaaat caaaaataag tcactaatta
      241 actaccactc caattgtaag ccttttttct cacttttttt caaaaatatg gtatgctttt
      301 taatggcttc aaatataaaa gagtttaaag cgtaacacac ttatggggaa gtggtttggg
      361 gtgcgcttta aactcttctt tattattatc tcacaattta acccaaatgt ctttctattt
      421 aaaaatcaaa gtaaaacttt tcaaatatac agaagtataa ctatgtgaaa catcctttca
      481 ttaatccata aaaggataca taaaaaagcc actcatttga gtggcaatga agaaaagctt
      541 tagcttgtat aatactcttc aaaaaaattc taacacagaa cgattcaaat ggctacgtta
      601 atgtaccctg taggactcga acctacgacc ggacggttat gagccgtctg ctctgaccaa
      661 ctgagctaag ggtactggtt gttgccacat aaagccataa acaatcaacc agtagaatgt
      721 gtggcaacaa acctgttatc gcatagcttg gagtgtgact atttatgggt gatagtgaag
      781 atatgcgata acatcactat tttatcgaat aatttttat
//
LOCUS       DACGMI010000160          814 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.172, whole genome shotgun sequence.
ACCESSION   DACGMI010000160 DACGMI010000000
VERSION     DACGMI010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..814
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.172"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
BASE COUNT          282 a          173 c          138 g          221 t
ORIGIN      
        1 acaatttcat ttgccataaa atcctccttc aagattaact acttaacaaa attataaaga
       61 gctttctaat aggggtcaag cccctaatta aagaccccta aaaacagaca aaaagacccc
      121 caaaaacaga caaaaagacc cctaaaaaca gacaaaaaga cccccaaaag attctgcaca
      181 ccttgggaga gtaagcatac agccgacggt aaagaggttt aaaaagaggt ttaaaaagag
      241 attataaaag aggaggcaaa atttcccgcc taaaaaactc ctgctttttt cctcaaacaa
      301 gttcgcgaat ttttctaaac tgggaaactc gctccctacg gtcactaaaa atgtgtgatc
      361 gctacgctct cacattatac tgcgcagtcg cctaaaggct cctttgctta aaaacagttc
      421 ataaagaact cctttgaaaa gttctgagcg tttgtttaag ccgttttaag acagtcttag
      481 tataaaaccc ttatcttgtt ctcaaagcgc cttacaggcg gtcagggcaa gccctaacaa
      541 ccctaaaatg ttctataaga cctctaaaat tagatctaag gcgttttaaa gttgttttgg
      601 tataattata taccagaacg tttaaaacgc cttaaaacgc aaattatagc catatgtatt
      661 tttacggaag ccggcacact catttgcaaa gcttcagctt tgcaaattcg gattcgctca
      721 ctcgaaaatt gatttgtttt gactctgatc gataggtgta ttttttagaa ggattgctag
      781 ccaaatacgg aggtatttgg tgcaaataac cgct
//
LOCUS       DACGMI010000161          767 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.173, whole genome shotgun sequence.
ACCESSION   DACGMI010000161 DACGMI010000000
VERSION     DACGMI010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.173"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..>767
                     /locus_tag="IXT46_003008"
     CDS             <1..>767
                     /locus_tag="IXT46_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HAQ4948850.1"
                     /translation="IRTLKEFKSYLPKQSKRILPRVLMVDEFRSHASIEDKMSFICAD
                     GETGQLIDVLPTRKLPRLTSYFLGCANPEEVKFLVTDMNAAYFQLTKRILPNAKVVID
                     RFHIIKHMNQAFNELRIREMNELRKVGQKSQAEKLKKNWRFLLKNRANINHYEYKTWK
                     SFRAPKYPFLTEAMMIDRLLGFSTSLKEAYPYFHELVEAFRDKDPDLFFSLLAELPET
                     LDDGFREKLQNLLTYEEGITNAMIYPYTNGKIEAKNT"
BASE COUNT          254 a          157 c          149 g          207 t
ORIGIN      
        1 attcgtacgt tgaaagagtt taaaagctac ttaccaaagc aatctaagag gattctcccc
       61 agagtattga tggttgatga atttcgttcg cacgcttcca tagaagataa aatgagcttt
      121 atttgcgcag atggcgaaac aggacaatta attgatgtct tgcctacgcg taaattgcct
      181 cgattaacaa gctatttctt aggctgcgct aatcctgaag aagtaaaatt tttagtcaca
      241 gacatgaacg ccgcctactt ccagcttacc aaacgtattc tgccaaatgc gaaagtagtg
      301 attgatcggt ttcatattat caaacacatg aatcaagcct ttaatgagtt gcgtatccgt
      361 gaaatgaatg aacttcgtaa agtaggacag aaaagtcagg cagaaaaact gaaaaagaac
      421 tggcgctttt tgctaaaaaa tcgtgcaaac atcaaccatt atgaatacaa aacatggaaa
      481 agttttcgag caccaaaata cccatttctt acggaagcga tgatgattga tcgattgctt
      541 ggcttttcta cgtccctgaa ggaggcgtat ccctattttc atgaattagt tgaagccttt
      601 cgagacaaag accctgactt atttttctcc ttattggcag aacttcccga aacgttagat
      661 gacggctttc gggaaaagct ccaaaacctt ctgacctatg aagaaggcat caccaacgcg
      721 atgatctatc cttacaccaa tggaaaaata gaagcgaaga ataccca
//
LOCUS       DACGMI010000162          766 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.174, whole genome shotgun sequence.
ACCESSION   DACGMI010000162 DACGMI010000000
VERSION     DACGMI010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.174"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            27..>766
                     /locus_tag="IXT46_003009"
     CDS             27..>766
                     /locus_tag="IXT46_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HAQ4948851.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRG
                     VQEVLLFITDGLKGMKDTIHQIYPKAKY"
BASE COUNT          278 a          143 c          131 g          214 t
ORIGIN      
        1 caattcacag aaaagaggac ttccctatga atgattttac tacagaaatt gtgcaaactc
       61 tagtcactaa aggcgattta aatgaattat tccgttcgca cttagaaaaa gcgataaaca
      121 cactcctacg gactgaatta acggcttttt tagattacga aaaatatgat cgcactggtt
      181 ttaattcagg taattcgaga aacggttctt actttcgatc aatcaaaacc gaatatggtg
      241 aattaacatt ggaaatacct agagatcgta atggtgagtt taaacaacaa actttaccag
      301 cctacaaaag aacaaacgat acattggaaa ccactattat ccatttattc gaaaaaggtg
      361 ttacgatgtc tgaaattgct gatttgatcg aaaaaatgta cggtcatcac tatactccac
      421 aaaccatgtc caacatgact aaagttctga ctgaagaagt aaatgccttt aaatccagag
      481 ccttaaatga taagtatgtc gctattttta tggacgctac ttacattcca ctaaaacgtc
      541 aaaccgtatc caaagaagcg atttatattg ccattggtat acgagaagac ggcactaaag
      601 aagtactgag ttatgcgatt gctccaactg aatcaacata cgtttggaat gagctgctac
      661 aggatattaa ctccagagga gttcaagaag tcttgctttt tattacggac ggcttaaaag
      721 gcatgaaaga tactatccat caaatttatc ctaaagcaaa atatca
//
LOCUS       DACGMI010000163          729 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.175, whole genome shotgun sequence.
ACCESSION   DACGMI010000163 DACGMI010000000
VERSION     DACGMI010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.175"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..703
                     /locus_tag="IXT46_003010"
     CDS             <1..703
                     /locus_tag="IXT46_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAQ4948852.1"
                     /translation="RRLPYLERYFSRFSLATREAVQLIVIDMYAPYVSLVKKLFPNAQ
                     LIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHSQRGLGKKLKRYWKLLQKEEAKLNY
                     EKRVWRASFKDYLTESEIADRLLAACPNLRQGYQLYQDILYAVKKRDQSLFEDCLTRD
                     ISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGPLECLNNHIKVLKRNAYGFRNFYNF
                     KLRIMIRHGKTFLTK"
BASE COUNT          235 a          147 c          136 g          211 t
ORIGIN      
        1 tcgacgcttg ccttatttag aacgctattt ttctcggttt tcattagcga ctcgtgaagc
       61 cgttcaattg attgttattg atatgtatgc gccttatgtt tcgttggtga aaaagctttt
      121 cccgaatgct cagttgatca tcgatcgttt ccacatcgtc caacatattg gcagaacttt
      181 cttgaatcat cgagtgaaag aaaccacggt acgacttaaa ggaaattccc actctcaacg
      241 agggttaggg aaaaaattga agcgctattg gaaactccta caaaaagaag aagcaaagtt
      301 aaactatgaa aaacgggttt ggcgtgccag ttttaaagat tatttgactg aaagtgagat
      361 tgccgatcga ctgttagctg cttgtcccaa cttacgccaa ggctatcagt tataccaaga
      421 cattctttat gcggtaaaga aaagagatca gtcactattt gaggattgtt taactagaga
      481 cattagcggt ctgccagaaa cctatacaac cactttacga acgtttaaaa agtttctgcc
      541 acagatccaa aatgcgcttc actacagcta ttcaaacgga ccattggaat gcttaaacaa
      601 ccacatcaaa gtattaaaac gcaatgcgta cggctttcgc aacttttaca atttcaaact
      661 acgaattatg attcgtcatg gcaaaacatt tttaaccaaa taaacagaac agaaagaggt
      721 tttcttctt
//
LOCUS       DACGMI010000164          717 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.176, whole genome shotgun sequence.
ACCESSION   DACGMI010000164 DACGMI010000000
VERSION     DACGMI010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.176"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            9..>717
                     /locus_tag="IXT46_003011"
     CDS             9..>717
                     /locus_tag="IXT46_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4948853.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISN"
BASE COUNT          251 a          126 c          135 g          205 t
ORIGIN      
        1 gagtacaaat gacctatacc catcttacaa cggatgaact tgtaataata gagtcttatt
       61 tcaaaatgaa tcaatctgtt gctaaaactg cccattgctt gaatcgttca agacaaacga
      121 tccataaagt atatctgttc ttcaagcaag gaaaatcagc cttagaatat tatcaacagt
      181 ataagaaaaa caaatcaaac tgtggtagac gtccgcttgt tttacccgag gaacaatcag
      241 aatatattca aagaaaggtt gttcaaggat ggacacccga tgtgattgtt ggtcgtgcag
      301 cgtttcctat tagttgttct gctcgtacca tttatcgtat gttcaaaaag gggctatttg
      361 attcttctga cttaccgatg aaaggcaagc gtaaaccgaa tggacatcaa gaaagacgtg
      421 gaaaacaaac tttccgccgc tctattcatg aacgtgaaaa ggattatagc caattctcaa
      481 atgagtttgg tcaccttgaa ggtgacacta tcgtaggtct gaaacataaa agtgctgtaa
      541 ttaccttagt tgaacgatta tcaaaagtta tcatcacatt gaaaccgtgt ggtagacaag
      601 cgattgatat tgaaaaaaaa ttaaatcaat ggtttgaatc tgtaccgaaa aacctattca
      661 aatccatcac ttttgattgt ggaaaggaat tttcaaattg gaaacagatc agtaatg
//
LOCUS       DACGMI010000165          696 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.177, whole genome shotgun sequence.
ACCESSION   DACGMI010000165 DACGMI010000000
VERSION     DACGMI010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.177"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(53..628)
                     /locus_tag="IXT46_003012"
     CDS             complement(53..628)
                     /locus_tag="IXT46_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4948854.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          125 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaacg
//
LOCUS       DACGMI010000166          658 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.178, whole genome shotgun sequence.
ACCESSION   DACGMI010000166 DACGMI010000000
VERSION     DACGMI010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..658
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.178"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            102..>658
                     /locus_tag="IXT46_003013"
     CDS             102..>658
                     /locus_tag="IXT46_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAQ4948855.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMM"
BASE COUNT          204 a          127 c          124 g          203 t
ORIGIN      
        1 ggtgaacttc accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc
       61 tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat actcagctta
      121 tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta
      181 aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag
      241 aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa
      301 ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac
      361 aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa
      421 aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata
      481 cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca
      541 tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag gtcttatgct
      601 ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc atgatgga
//
LOCUS       DACGMI010000167          638 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.179, whole genome shotgun sequence.
ACCESSION   DACGMI010000167 DACGMI010000000
VERSION     DACGMI010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.179"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..525
                     /gene="tnpB"
                     /locus_tag="IXT46_003014"
     CDS             <1..525
                     /gene="tnpB"
                     /locus_tag="IXT46_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAQ4948856.1"
                     /translation="KMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLH
                     EKVMNQRTDFLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQ
                     YKADWYGRKIIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASIN
                     ILTEGLRLHSMGLA"
BASE COUNT          238 a          101 c          123 g          176 t
ORIGIN      
        1 aaaatggaaa agaaactaaa gcgtgaacaa cgcaaattgt ctaggcgtgc tttattggct
       61 aaaaataaag gtaccaatct atttgaagct aaaaattatc aaaaacaaaa acgcaaagta
      121 gctagattgc atgaaaaagt aatgaatcaa cgtactgatt ttctgaataa gttgagtaca
      181 gaaatgatca aaaatcacga tattatctgt attgaagact taaacacaaa aggtatgttg
      241 cgaaatcata aattagctaa aagtatttct gatgtttctt ggtcaaagtt tgtgactaaa
      301 ttacaataca aggctgactg gtatggacga aaaatcatca aagtagataa atggtttccg
      361 tctagtcaga tttgttcaga gtgcggacat aaagatggca agaaatctct tgaaattcga
      421 gaatggactt gtcctgtttg tcatactcat catgatcgtg atatcaatgc tagtatcaat
      481 attctgaccg aaggtctaag actacattct atgggattgg cttagatcca atcatcaaga
      541 accgtaggaa ctacggggat agcttggtaa ataagagaca ccgctgttag taaagaaata
      601 cgctatcaag tatgctctat tcccaagaag ctcccact
//
LOCUS       DACGMI010000168          529 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.180, whole genome shotgun sequence.
ACCESSION   DACGMI010000168 DACGMI010000000
VERSION     DACGMI010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.180"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(5..90)
                     /locus_tag="IXT46_003015"
     tRNA            complement(5..90)
                     /locus_tag="IXT46_003015"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="IXT46_003016"
     tRNA            complement(107..178)
                     /locus_tag="IXT46_003016"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="IXT46_003017"
     tRNA            complement(190..262)
                     /locus_tag="IXT46_003017"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="IXT46_003018"
     tRNA            complement(280..361)
                     /locus_tag="IXT46_003018"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="IXT46_003019"
     tRNA            complement(369..441)
                     /locus_tag="IXT46_003019"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="IXT46_003020"
     tRNA            complement(445..517)
                     /locus_tag="IXT46_003020"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          136 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactta
//
LOCUS       DACGMI010000169          507 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.181, whole genome shotgun sequence.
ACCESSION   DACGMI010000169 DACGMI010000000
VERSION     DACGMI010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.181"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..>507
                     /locus_tag="IXT46_003021"
     CDS             <1..>507
                     /locus_tag="IXT46_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
                     /protein_id="HAQ4948857.1"
                     /translation="ATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVW
                     NELLQDIYSRGVHDVLLFITDGLKGMKDTIHQIYPKAKYQHCCVHVSRNIAHKVRVKD
                     RKEICDDFKAVYQASSKEEANTFLGSMIEKWQKTYPKVTQSLIKNQDLLTFYEFPPGI
                     RRSIYSTN"
BASE COUNT          164 a           94 c          100 g          149 t
ORIGIN      
        1 atgctactta tattccttta aaacggcaaa ccgtctccaa agaagcaatc tatattgcca
       61 ttggtatacg agaagacggc actaaagaag tactaagtta tgcgattgcc ccgactgaat
      121 cgacctacgt ttggaatgag ttgttacagg acatttactc cagaggggtt catgatgtct
      181 tactgtttat taccgatggc ttaaaaggca tgaaagatac gattcaccag atttatccta
      241 aagctaaata ccaacattgc tgtgttcacg tttcccgtaa tattgctcat aaagtacgtg
      301 tcaaagatcg aaaagaaatc tgtgatgatt ttaaggctgt ttatcaagct agctcaaagg
      361 aagaggcaaa taccttttta gggagtatga ttgagaagtg gcagaaaact tatcctaaag
      421 tgacgcagtc actgataaaa aatcaagatt tattgacttt ttatgagttt ccgcctggta
      481 tccgccgaag catttactca actaatt
//
LOCUS       DACGMI010000170          495 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.182, whole genome shotgun sequence.
ACCESSION   DACGMI010000170 DACGMI010000000
VERSION     DACGMI010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.182"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            <1..290
                     /locus_tag="IXT46_003022"
     CDS             <1..290
                     /locus_tag="IXT46_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948858.1"
                     /translation="GYRCYKMSYYVSPSKCKQLARQTNKLNTVSAIANFIGLSGLTPG
                     IISLVFGSAVSANNVFVTAARRGKGVQLNYIAHFSNTTTYNYSSNQNYVIK"
BASE COUNT          171 a           76 c           75 g          173 t
ORIGIN      
        1 ctggttatag atgttacaaa atgagttatt atgtaagtcc ttctaaatgc aaacaattgg
       61 ctcgccaaac taataaactt aataccgtct cagctattgc aaactttatt ggactatctg
      121 gattaacacc ggggattata tcattagttt tcggatcagc agttagtgct aataatgtat
      181 ttgttacagc cgctagaaga ggaaaaggcg ttcaattaaa ttatattgcc cattttagta
      241 ataccactac ctataattat agttctaacc aaaattatgt tataaaataa ttaaaacttt
      301 aaactaggag gaatgcttta tgaaattaac aaaaattgct gtaattttag ctgttattgc
      361 tggcattatt ttatattttg tattgcctgc taatcaattc ttcctttact ttggaatacc
      421 tgcgatttta atagtaaatg gcgtaagaat ctttgaacaa cgaaaaaaat gtagctctac
      481 ctaatcgtta caaaa
//
LOCUS       DACGMI010000171          492 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.183, whole genome shotgun sequence.
ACCESSION   DACGMI010000171 DACGMI010000000
VERSION     DACGMI010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.183"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            51..>492
                     /locus_tag="IXT46_003023"
     CDS             51..>492
                     /locus_tag="IXT46_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HAQ4948859.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKE"
BASE COUNT          179 a           74 c          100 g          139 t
ORIGIN      
        1 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
       61 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
      121 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
      181 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
      241 agaaaaataa aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag
      301 gaaaatggca ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt
      361 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
      421 ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga
      481 aactaaaaga at
//
LOCUS       DACGMI010000172          488 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.denovo.184, whole genome shotgun sequence.
ACCESSION   DACGMI010000172 DACGMI010000000
VERSION     DACGMI010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.denovo.184"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..413)
                     /locus_tag="IXT46_003024"
     CDS             complement(<1..413)
                     /locus_tag="IXT46_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948860.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPF"
BASE COUNT          185 a           78 c           62 g          163 t
ORIGIN      
        1 aaaaacggct ttccaaatga tgaaatacct aaatctaact tattaagaaa gttgaaattt
       61 ttatattcag gaaaccattt attaatttca tgtgcagcac gtaatgcatt ccctggagtt
      121 gtcaaagaga aaattaattc tgctaagctt attattgaaa atactgataa cttataatta
      181 tatcgtccat tgacaatcaa atataaacta actatacttg ttagaacaaa aaaacaggcg
      241 ttgacttgtt cttgattagt taaaaatatc aataaaggaa tacttaccca atatattttt
      301 ctatttattt cttctcctct taagagttga aaaaacggat aaaaagttag taaactaaat
      361 gctactggcc actgatagtt caaggtggtt gctctccaac cggtttcccc cattactgtc
      421 aatggtatta aacagtatat agagcaaacc aataataaat ttttaacatt tattttctca
      481 aaaacata
//
LOCUS       DACGMI010000173        39475 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.guided.024, whole genome shotgun sequence.
ACCESSION   DACGMI010000173 DACGMI010000000
VERSION     DACGMI010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39475
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.guided.024"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            196..2295
                     /locus_tag="IXT46_003025"
     CDS             196..2295
                     /locus_tag="IXT46_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAQ4948861.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            2491..3354
                     /locus_tag="IXT46_003026"
     CDS             2491..3354
                     /locus_tag="IXT46_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAQ4948862.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            3459..3932
                     /locus_tag="IXT46_003027"
     CDS             3459..3932
                     /locus_tag="IXT46_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4948863.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            4028..4915
                     /gene="xerD"
                     /locus_tag="IXT46_003028"
     CDS             4028..4915
                     /gene="xerD"
                     /locus_tag="IXT46_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAQ4948864.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            4934..5305
                     /locus_tag="IXT46_003029"
     CDS             4934..5305
                     /locus_tag="IXT46_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAQ4948865.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            5275..6072
                     /locus_tag="IXT46_003030"
     CDS             5275..6072
                     /locus_tag="IXT46_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAQ4948866.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            6056..6625
                     /gene="scpB"
                     /locus_tag="IXT46_003031"
     CDS             6056..6625
                     /gene="scpB"
                     /locus_tag="IXT46_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAQ4948867.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            6631..7347
                     /locus_tag="IXT46_003032"
     CDS             6631..7347
                     /locus_tag="IXT46_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAQ4948868.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      7429..7554
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7677..8288
                     /locus_tag="IXT46_003033"
     CDS             7677..8288
                     /locus_tag="IXT46_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4948869.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            8667..10190
                     /locus_tag="IXT46_003034"
     CDS             8667..10190
                     /locus_tag="IXT46_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAQ4948870.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            10427..11767
                     /locus_tag="IXT46_003035"
     CDS             10427..11767
                     /locus_tag="IXT46_003035"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAQ4948871.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            11920..12657
                     /locus_tag="IXT46_003036"
     CDS             11920..12657
                     /locus_tag="IXT46_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAQ4948872.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(12822..13043)
                     /locus_tag="IXT46_003037"
     CDS             complement(12822..13043)
                     /locus_tag="IXT46_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAQ4948873.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            13074..14105
                     /locus_tag="IXT46_003038"
     CDS             13074..14105
                     /locus_tag="IXT46_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948874.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            14092..15495
                     /locus_tag="IXT46_003039"
     CDS             14092..15495
                     /locus_tag="IXT46_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAQ4948875.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            15561..16196
                     /locus_tag="IXT46_003040"
     CDS             15561..16196
                     /locus_tag="IXT46_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4948876.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            16245..16925
                     /locus_tag="IXT46_003041"
     CDS             16245..16925
                     /locus_tag="IXT46_003041"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAQ4948877.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            17060..18289
                     /gene="rpsA"
                     /locus_tag="IXT46_003042"
     CDS             17060..18289
                     /gene="rpsA"
                     /locus_tag="IXT46_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAQ4948878.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            18471..19781
                     /locus_tag="IXT46_003043"
     CDS             18471..19781
                     /locus_tag="IXT46_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAQ4948879.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            20024..20299
                     /locus_tag="IXT46_003044"
     CDS             20024..20299
                     /locus_tag="IXT46_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAQ4948880.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            20534..21580
                     /locus_tag="IXT46_003045"
     CDS             20534..21580
                     /locus_tag="IXT46_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948881.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            21582..22841
                     /locus_tag="IXT46_003046"
     CDS             21582..22841
                     /locus_tag="IXT46_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAQ4948882.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            22847..23428
                     /locus_tag="IXT46_003047"
     CDS             22847..23428
                     /locus_tag="IXT46_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAQ4948883.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(23510..24385)
                     /locus_tag="IXT46_003048"
     CDS             complement(23510..24385)
                     /locus_tag="IXT46_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4948884.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            24533..24865
                     /locus_tag="IXT46_003049"
     CDS             24533..24865
                     /locus_tag="IXT46_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAQ4948885.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            24977..26185
                     /locus_tag="IXT46_003050"
     CDS             24977..26185
                     /locus_tag="IXT46_003050"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAQ4948886.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            26339..26794
                     /locus_tag="IXT46_003051"
     CDS             26339..26794
                     /locus_tag="IXT46_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948887.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            27156..27431
                     /locus_tag="IXT46_003052"
     CDS             27156..27431
                     /locus_tag="IXT46_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948888.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            27444..29522
                     /locus_tag="IXT46_003053"
     CDS             27444..29522
                     /locus_tag="IXT46_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAQ4948889.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            29682..31568
                     /locus_tag="IXT46_003054"
     CDS             29682..31568
                     /locus_tag="IXT46_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4948890.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            31580..32527
                     /locus_tag="IXT46_003055"
     CDS             31580..32527
                     /locus_tag="IXT46_003055"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAQ4948891.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            32547..33074
                     /locus_tag="IXT46_003056"
     CDS             32547..33074
                     /locus_tag="IXT46_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4948892.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(33137..33790)
                     /locus_tag="IXT46_003057"
     CDS             complement(33137..33790)
                     /locus_tag="IXT46_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAQ4948893.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            33922..34764
                     /locus_tag="IXT46_003058"
     CDS             33922..34764
                     /locus_tag="IXT46_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4948894.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            34922..35818
                     /locus_tag="IXT46_003059"
     CDS             34922..35818
                     /locus_tag="IXT46_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4948895.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            35821..36534
                     /locus_tag="IXT46_003060"
     CDS             35821..36534
                     /locus_tag="IXT46_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAQ4948896.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            36554..37072
                     /gene="msrA"
                     /locus_tag="IXT46_003061"
     CDS             36554..37072
                     /gene="msrA"
                     /locus_tag="IXT46_003061"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4948897.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            37069..37296
                     /locus_tag="IXT46_003062"
     CDS             37069..37296
                     /locus_tag="IXT46_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAQ4948898.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            37448..37999
                     /gene="lepB"
                     /locus_tag="IXT46_003063"
     CDS             37448..37999
                     /gene="lepB"
                     /locus_tag="IXT46_003063"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4948899.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(38082..38624)
                     /locus_tag="IXT46_003064"
     CDS             complement(38082..38624)
                     /locus_tag="IXT46_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAQ4948900.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(38861..39259)
                     /locus_tag="IXT46_003065"
     CDS             complement(38861..39259)
                     /locus_tag="IXT46_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4948901.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT        13671 a         6693 c         8209 g        10902 t
ORIGIN      
        1 ttctgattca tcagtcccat aaattataga gccaaaaaag cttgagacta cgcagtctca
       61 agcttttttt tctataggaa ggaaattcat tcattatttt taagtaaatc ctaaaaataa
      121 gctattggcg tgacgtatag aatatgatag attaaatggt agcgtaaacc tagtaaagga
      181 gccgatcgct aagtgatgaa aaaatgtcca aattgcggat cgaaaaaaat ggagcagaat
      241 actatctgtc cagactgcgg tcatcaaata actgcagaag atcagcaaat aaaagaatca
      301 attgaagaaa caaatacaga tgcagctatg caggataaat caactgaaga tgcagtcttt
      361 cctgatacag aattaaacga tccaatcgaa tggtcggaat tgaaagattt acctctagaa
      421 tctgtaatgg aattattcga aaaagcagaa ccagaagacg aagaaccacc tgctcacgat
      481 caagtaacta atatagagaa aaatgaacag aagaaagcaa ctgttcatga gacttcggaa
      541 gaatcaggaa agaatcaaga agaaacgctt gaatcaaaac aaaaaagaag agtagctgaa
      601 ctgaaagaaa tcgtcgataa tgaggaagaa aattcgatac tatccgctta tatcaaagca
      661 catcgtgaag atacaaaaga agagcacgcg aaagagctgc tcaaaatgat cagtgaaaaa
      721 attgcacagg aaaacaaagt agagccagaa aaggaacaag aaactgaaaa agactctgat
      781 agagaaaacg ccacaggtaa agaaacagta aaaataaaag acgtaaaaac ggatatcaca
      841 gaaaaaactg aagtatttac tgaaaaacaa ttagaaaagg aaaaaacgaa taaactgccg
      901 gaagcagaga aaaaagaaat actcgaaaac acagacaaaa agtcaacaga gcccgatgaa
      961 ataaatagtg aatccgatgc tgaaaatcaa tctgtaagca aagagggtac tgatcttgaa
     1021 gcaaaaatag aaaaagaaga gaaccagcct aagctgtttg aagcagaagc gaaatcaata
     1081 acaatcgtgc cagatactga aaaaacacat caagaatcaa acttagaaaa aacagatcca
     1141 gataaagcgc aaaagaaaaa atcaaaaaaa gtaccttatc tcgttttagc agcagtactt
     1201 ctactcggtg gaggaagctg ggcttattat gaccatcatc aaaaagtaga agccgaagta
     1261 gcagcagaag caaaaagaca gcaacaaatg gaagaacttc atgagaaact tgctgccttt
     1321 tatacagatg atcaccatca atttattcgt gcagatatga ttcatcaaga tttatcaaaa
     1381 ctaaaaaatg atttatccag tcttaagaat gaaaaaggat attcagagtt agaaacaact
     1441 taccaagata tccaatctaa gatccgagat atccaaaaag tgaatgagtg gttcatagca
     1501 cctgccatcg tcgatgatca tctagcagat gacatcaagt tgaaagcaga taaagagatc
     1561 caagcaatcg aaacggataa cacagatttt ggaaaattga ttcaacaagc acaaacagaa
     1621 gctaaaaatc aatatgctga attgcaaaca gctaaagaaa aaacagctat agtctttaaa
     1681 gacggaaaag tagtggattc agcaacacgc gaccaataca agacggcaaa agaagcagta
     1741 gaaaaagtga aaaatacaga tctatctgct cagttgaatg aacaattgaa acaagtagat
     1801 aagatgctca ctgataaaga gaaaaaagaa gaagaggaaa agaaaaaagc agaagaagcg
     1861 aaaaaagcag ctgaagaaca agcaaaacaa gccgctcaag cagcagctgc agctcaagcc
     1921 gctcaacaag ctgcggtcgc acaagcagca cagcaagaag cggcatcctc gaccccttcc
     1981 tcttcaaact cagcgaatca gccaatcaaa tctgccagag caagtgatat tgccgatgca
     2041 tctaatccag catggacgtg ggcaccaggt gtccaaagca aagtgattgc tacatgtatc
     2101 caacgtggat atatcgttga aggaggttac agattagaaa aagccagaat cgaaaatggg
     2161 gaaggctatt ataatctata tgccacttca acaaaatctg cattgatgaa aggcattgga
     2221 gaaagtgctt tgccatttta catcgtaacc atcaactgta aaactggatg gttcggagga
     2281 aatgggagca attaatttta ggcaaatgaa agaggctgtg agcctgccgt ttaacaccgt
     2341 ttattcgaaa aaggggagta tgacacaact gttgtcatac tccttttttc acctttccaa
     2401 accaaggctc agctattcaa gtagataaca ttatgttatg atagcaaaga aatgtattaa
     2461 gaaaaccttt cactatagag ggagaaaaaa atgaacgatt tattagcaac tatatttaca
     2521 ggtattatta ttgatgaaaa tgaaaaaaac tactttgtcc aaaaaaacgg acaaaccttt
     2581 ggcttaagca aatcagaagg tgaacacaaa atcggtgaag cagttgaagg attcggttac
     2641 caaaatcaaa aacatgaaaa tcggatcact acacaaattc ctaaaagccg tatcggtcat
     2701 tacgcttttg gaatcgttac tgctacacga aaagatttag gtgcgtttgt cgatatcggt
     2761 cttccagata aagactttgt cgtatctctt gatgaattgc cgacaatgac agagctatgg
     2821 cctaaaaaag gggatcgctt gatgatttcc cttagagttg atgcaaaaga ccgtatttgg
     2881 ggcagtttag cagatgaaaa aatattcaaa tctttaagca aatatggaac agaagaaatg
     2941 aaaaacaaag atgtgatagg aacagcatac cgcttgaaat taacaggtac gtacgtttta
     3001 acggaagatt tctatcttgg gtttatccat ccttctgaac gatataatga acctcgtcta
     3061 ggcgagcaga taaaaggtcg agtgattggt gtccgaccag acggtgtact gaatctttca
     3121 ttgaagccaa gagcatatga agctatatca gatgatgcac aaatgatttt aaccatttta
     3181 gaacgttctg cagatcagca aatcaacttt acagataaat cggatccaga agaaatcatg
     3241 aaagcttttg gtatcagcaa aggagcattt aagcgcgcat taggtaatct tttgaaacaa
     3301 ggattgatta cacaagaaaa cggtgtgaca aaactagtca aaaaatctaa ttgagaatcc
     3361 cttgcatgtt tttcttaact agcttataat aattttaatt aacatagtgt tatatctttt
     3421 tttatttgta attattataa attgttgggg ttgagtaaat ggtcatgaat gctatttcgg
     3481 cgatgaaaaa aacaaaacag cagctacatg aagcggggtt taagctgaca ccgcaaagag
     3541 aagctactct gcttgtgctt ttggaaaatg agaaagagca tttatctgca gaagaaatct
     3601 tctttttagt gaaaaaaaag agtccggaaa ttggacttgc tactgtttat cgaacccttg
     3661 aaatcttgac agaattgaaa attgtcgata aagtaagttt taatgatgga ttagcccgtt
     3721 atgatttgag aaaagaaggc gccaaacatt tccatcatca tttactatgc ttgaactgcg
     3781 gcacgatcga ggaagtagaa gaggatcttt tacttgaagt ggagcaagta gtagaagaac
     3841 gttatcattt tttagtaaaa gatcatcggc taacgttcca tggaatctgt caggaatgct
     3901 atgaaaaaga aaaaagaaac cagtccgtct gagtgtctag acggcttttt ctttgctcag
     3961 attatggaaa aagactatca gaatgaagcg gtatctgata tgatagagag gcatgagggg
     4021 gattattatg aaagagcaaa tcaacgatta tctccactac ttgaatattg aacggggatt
     4081 gtccgccaat acacgacaaa gctatgaacg tgatttggaa cagtacttgc attttctaca
     4141 ggagcagaaa attgcttcat ggcaggatgt cgatcgcttt ttagtcatcc gttttctgga
     4201 gaagttgcat gaagaaaaaa aagcgacagc aactgttact cggatgatct caagtctcag
     4261 aagattccat cagtttttac ggcaagagcg tatcactgat catgatccga tgcaacatat
     4321 cgatacgccg aagaaagcac agaaattacc aagtacattg actctgacag aagtagaaaa
     4381 gctgattgaa gcacctgata cgacaaaaac gttagggata agagatcgtg caatcttgga
     4441 agtcatgtat gctactggga tgcgcgtcag tgaattgatt ggattgaaat tgggagatct
     4501 tcatctttct cttggactgg tacagacagt tggaaaagga gataaagagc ggatcattcc
     4561 tttaggtgat tatgcgatcc aatggctgga acgctactta gacgaagcac gtccattact
     4621 tgtaaaggac gcatctgaaa tgcatgtatt tgtcaataat catgggaaag gtctttctcg
     4681 gcaaggaatc tggaaaaatc tgaagcagtt agtacgagag gctgggattt acaaagaagt
     4741 aacaccacat acgctgcggc atagctttgc cacacatctg ctagaaaatg gagctgattt
     4801 gcggacagta caggaattgt taggtcacgc ggatatctct acgactcaga tttatacaca
     4861 tatcacgaag aaaagaatga cggatgttta taagcagcat tttccaaggg cttagtcata
     4921 ggaaggtgag aagatgttaa cacattaccg gaaagaaaac cgtaaaattg ctatgggact
     4981 attgagtttc cataagaaac tgacaggtaa aacttctttg ttgaaggaga ttgatacgta
     5041 cgaatctgaa gacgattatg aacttttttt ctttacgcca gaaggttcaa ccaacattca
     5101 agggattatt ggtatttact gggcaacgaa cgatcagctg atcatccatg acatttcttt
     5161 gaatccgtct tatcgcggtg agaatatggg ctttcaaatg ttagatgaat tacaggaaaa
     5221 gtacccggat gtctccatcc gtgcaactga aatcacagag ccttacattg gaaaatggct
     5281 agcaaagaaa aagaagaaag agtgaatgag ttgacggaga tcaatattaa attagatgta
     5341 ttcgagggtc ctctcgatct gctgcttcat ctgattcagc aaatggaaat cgatatatat
     5401 gatataccga tcgctacgat cacggagcaa tatatgaatt atatccatac aatgaaaaca
     5461 ctcgagctag ctgttgcagg agaatactta gtgatggctg ctacattgat ggcaatcaaa
     5521 agcaagacat tgcttcctgt ccaagaattc gtcacagacg atgaagaatt atgggaagaa
     5581 gatcctcgag aagaattggt cactcagctt ttagaatacc gtaaatataa atatgcagct
     5641 gaaagactga cagaaaaagc agaggaacga agtctttatt acacaaaaga acctatgaac
     5701 atcgatgggt tagcggatgc tgaaaagccg ttgaagcgag gacaagtcaa aaaaatcgat
     5761 ttgatccgtg ccatgcagaa aatcttagaa cgtaagaaat tttctcaaaa agtggaaaaa
     5821 acgatcacgc ccgatgacac aacgatcgaa gaacgaatgg tatttatcga agagcgtata
     5881 aaaagaaatg cgcatggctg tactttcgat tctttttttg agtcaccttc taaaagtgaa
     5941 gttgtcacta cttttatggc tttgctagaa ttgatgaaaa aagggcagat cattgcgcaa
     6001 caaaaagaaa actatgaatc aattatgctt tatccagcag taggagatac cgaacatgac
     6061 gaaattaagt gaacttgaag cccttctttt tattgttggc gaggaaggga tcagtaatga
     6121 agaattaagc ggactgttaa atctcagcga agcagaagtc acaagtttag tgaaagaatt
     6181 aaaagaatct tacactcaaa actcgcactc agctttgcat atttttgaaa cggaaagcca
     6241 ttatgtatta acgactaaaa aagagctggc tcccttactt aagcgatatg cgcaagggac
     6301 atcaaacaca ttatctcaag ccgccgtcga aaccttagca atcatcgctt ataaacagcc
     6361 aatcacaaga gctgaaatcg agcagattcg aggagttcag gtttcaggag cggtacagcg
     6421 tctagctgcc cataaactga ttgaagaaaa aggtagagta gaaggaccag gtcggccgat
     6481 attatatgga acaactggct acttcttaga ttattttggt ttgaaatcat tagaagaact
     6541 gcctgataca caagaaatgg aaatttcact tgaagaagac gtgtcaccag atctattctt
     6601 tgatggaatg aataaaggag aataattgta atggagagat tgcagaaagt aattgcccac
     6661 gctggcatca cttctcgtcg aaaagcagaa gaattcatcc ttgcaggacg tgtaaaagta
     6721 aacggacaag ttgtaaggga attagggata aaagttggga aacatgacac tgtggaagtg
     6781 gatgaagtcc caatttatca agaagaatac ggttactatt tattgtacaa acctaaagga
     6841 gttatttctg ctgttgcaga tgacaaagga agaaaagttg ttacggatct tttgccgatg
     6901 gtaaaagaac gtatctatcc tgtaggtcga ctggattacg atacttcggg gatcttgcta
     6961 ctgacaaatg atggagattt tgctcagcgc ctgacacatc caaaacatga agtggataaa
     7021 gtttacgttg caaaggtaaa agggatcgct acaaaatcga tgcttgcacc tttgacaaaa
     7081 ggaataaaga tcgaaggacg aaaaacatct ccagctaaat tccaaatttt atcagtggat
     7141 cctaagacaa accacagtat cgtggaattg acgatccacg aaggacgtaa tcatcaagtg
     7201 aaaaatatgc ttcaagcagt tggtcttcct gtgcaaaaac taaaacgtga aaaatacgga
     7261 gatctgactt tacaaggcct acgtcctggg gattaccgtg aactgaacaa aaaagaagtc
     7321 agcagtttgc tgaaccactc aaaatgaaca cttacttttt ataagtgtta gatgttgcgt
     7381 tttttgaata gatatgtata atgaatatgt aaacaaaaat tatataaggt tcgtcttcag
     7441 gggcagggtg aaattcccga ccggtggtta tagtccacga cctattttgc aaaaaaatag
     7501 ctgaatcggt gaaattccga taccgacagt atagtctgga taaagaagat agagcttatt
     7561 tgacgacgct tgatcaaata actctaactc tattttccct ggaaaataga gttttttcat
     7621 ttggagagaa acgtcaaaaa gttcgctgaa gaggagtcct aacaggagga tttcaaatga
     7681 agaacacccg tgtacagaaa atggttgcag tagcgatgtt tgctgcgatc gcattagttt
     7741 tacagtattt tgcttttccg atcatgccgg cttttagttt tttgaagatc gattttagtg
     7801 atatctcggt attgatcagc atgttcttat tcggtccagc ggccggagtt gcaacagcgt
     7861 tcttgcgttc agtattacat ctgctgacta caggtttttc tccggataat ttggtaggag
     7921 acactgctag tttcttatca acaacgatct ttacattccc gatttattat ttctttagtg
     7981 taaagaaaca gcataaagga agaaacaaat ttttaggtgt cattacagga accatcgctc
     8041 taactatttt tatgagtatc gcaaattatt tcgttattac gcctctttac ttaatgtttt
     8101 tagggctgaa cgcaacacag atgctgggca tgtctttagc aaactatgta ctgattggga
     8161 tcgttccttt caacttgatc aaaggattca tcgtgagtgc tgtcttttta gtgctgcatg
     8221 cgcaacttct tccatggtta agtcgaaaac aacatcagtt cgaacaacgt catacagcag
     8281 tcaaataaat atcaaaaaga tcaagaaatt tcttggtctt ttttttttgg aaaaaaatac
     8341 aagacatgca ataatgtaaa cgttttattt gtttgttttg agtatttttt tgatttatgc
     8401 ataaaaatca atcaattctt tgcaaatgtg aaattcttct ccttttaaaa gacgaaaatg
     8461 tttgtttata aaaaaaagga aacgctacaa tgaaaaagaa gaaagcttta aaaacctgaa
     8521 aaaagaggag ggaataggga aaaacgaact ttttgaacaa aagttttaca aaatgcgtgt
     8581 tattattttt gttctgatac tctttttgat aaaataacat tagagccaaa attgttgtct
     8641 ctaacggaaa agaaaggaag aagaagatgg aacaaacaaa aaagaaaaaa tttcaaatgc
     8701 cttcagcgta tacggtctta tttattatta ttgcagtaat cgctgtactt acttggttta
     8761 taccagctgg gcactatagt gtagacgatg caggcaacat cgtcgctgga tcatatgaac
     8821 gagtacaaca aaatcctcaa gggctgtggg atattttcat ggcgccaatc aatgggatgc
     8881 taggtgtacc agcgggggag ctaactaaag aaacacctgc tgcaatccca atctctttct
     8941 tcattttggt tgttggtgga tttttaggta ttatcaacaa aacaggggca ctagatgccg
     9001 ggattgcttc agttgtgaag aaattcaaag gaaaagaaaa aatgcttatt ccagtattga
     9061 tgctgttatt tgcattaggc ggctctactt acggaatggc agaagaaacg attccattct
     9121 atgctttact gatcccagtc atgatggctg taggctttga tacagtagta gctgtagcaa
     9181 tcgtattagt agggtctcaa gtaggctgtc tagcttcaac ggtaaatcct tttgcaacag
     9241 gcgtagcttc acaagctgtt gggatttcga tgggtgaagg tattggtctt cgattcttga
     9301 tgttcgttat tttgttagct atttctattg tatatgtgta tcgttatgca tcaaagatcg
     9361 aaaaagatcc aacaaaatca ttagtataca accaacgtaa agaagatatg aagcatttcg
     9421 atattgaagc aatcggtcgt caagaagtaa tcacgaaaaa acaaaaacat gttaatgtat
     9481 tgttctttat tacttttggt atcatgatca tcagtttgat tccttggaca accttgaatg
     9541 cgaatttcac gatttttgaa tcattgacaa actggttaac aaaccttccg gtactaggta
     9601 cggttctagg taaaagcatg cttccattag gtgactggta cttcccagaa attactatgt
     9661 tattcttagt aatgtccatc gtagtagcaa tcacttatgg catgaaagag tctgaatttg
     9721 tctctgaatt tttagctggt gcttctgatt tgatcggtgt agcaatcgta gtagctgttg
     9781 ctcgtggtat ccaagtggtt atgaacaatg gattaatcac agacaccatc ttacattggg
     9841 gcgaacaagg attaagttca ttatcttcaa gtgtattcat cattattaca tttattttct
     9901 atatccctat gtcattcttg attccttcaa cttccggctt agctgctgca acaatgggaa
     9961 tcatgggacc tatgggtgaa tttgccggcg tcggtaagga tttagtaatc actgcttatc
    10021 aatctgcatc tggtttagta aacttaatta caccaacatc tgctatcgta atgggtgctg
    10081 tagcaattgc tcgtttcgat gtttcagtgt ggtggaaatt taccggtaaa ttaattgcga
    10141 tattatttgt agccatctgt gtgatcctag gtgtagcagc aatgttctaa acctagacaa
    10201 atacaggtac aaggtctatc ataagaatga agaaaccgat aaacggctat cgataagcac
    10261 gtggataagt caatagctcc attcagtgag tgttttttct ttcatcattt gttaagaaca
    10321 ttctgcttgc tgatggagca ggcttaaaac gtcattattt gagaagaaga ggttgtgtcg
    10381 gaggaatttg acatgaccct ttttaacata ttaggaggat aatatcatga aaaaatttgt
    10441 gacagaacaa catcatgaac aagcattaga atcattgagc gaattgatcc gaattccttc
    10501 cgtactagat gaagcagatt caggacaagg acatcccttc ggtaaaaaag tgattgaagc
    10561 tttggataaa gtattggaaa tcagtgaaaa gctaggattt agaacattta aagatccaga
    10621 aggctattac ggttattcag agattggctc tggagatgaa ttattcggta tcttgtgtca
    10681 tatggacgtt gttccagcag gggacgaaaa taattgggaa acaaaaccat tcgatccaac
    10741 tataaaagac ggctggttag ttggtcgcgg atcccaagat gacaaaggtc cttctattgc
    10801 ggcaatgtat gccgtcaaag ctttgattga tgctggcgtg gaattcaaga cacgtattcg
    10861 ttttatcttt ggtacagatg aagaaaattt atggcgttgt ttagaaaaat ataacgaaaa
    10921 agaagaagga attacgcaag gatttgcgcc agatgctgaa tttcctttaa tttatgcaga
    10981 aaaaggctta ttgcaagctt acttgacagg accaggaacg aacgagtttt ctgtaaaagc
    11041 tggaggagcg ttgaatgttg ttcctgatgc agctccttac tctggagaaa agctttctga
    11101 agtaaaagaa gcattgaaaa aacacgaatt cgatttcgaa gaacaaggtg aaggcatcgt
    11161 cgttcttggt aaaagtatcc acgcgaaaga tgcagcacaa ggagtgaatg ctatttctcg
    11221 tctggcaatt gctctttcag aagtatttga ttttggccca atcaatttct taggaaaatt
    11281 agttcaagaa aatgcaactg gtgaagctgt cgtgggcaaa acagaagatg aacaatccgg
    11341 cgagctaacg atgaactttg caagtttgga aatcacacca gaacaaacaa aaatcggtgt
    11401 agatatgaga atccctgtta cattcaagaa agatgattta gtagctaaat taactaaaac
    11461 agcagaaaaa tatgggttga cttatgaaga atttgacttc cttgattcat tatacgtgcc
    11521 actagacagt gagttagtga aaaatctatt ggggacatat cgcgatatta ctggagacat
    11581 gactgaaccg tttgtatcag gcggcgctac ttttgctcgt acgatgaacc agtgtgtggc
    11641 attcggtgcg atgttccctg atactcctga ctttatgcac caggcgaatg aacgatggga
    11701 attaagtagt atgtataaag caatggaaat ttatgcagaa gctgtgtatc gtttatgtgc
    11761 taaataaaaa taaacataca aaaagggcgg atattcaaat ggatattccg tcttttttta
    11821 tttgatgctg gaaagtttgc atttctctct tattttttta aggtataatc atacttgatt
    11881 aagaaaaagg ggtcactcag atagaaaagg tgggagaaag tgaaaatatt tagacgaata
    11941 ctaattggct tagtcatcat tttaggatta ctcggtggag ccggttatta ctatatacag
    12001 caaaatacgt acgaaccatc gtcagaagcg caagtgttgg taaaagaagg aaaaaacaaa
    12061 gaagattact tattttttga aggagagaaa aagaatcatg gaaagtctcc attacttatt
    12121 ttttatcctg gtgctctcgt agagccagaa agttatagta tttgggcgca agatttagca
    12181 aaaaacggct tttcagtcgc tattgtcaaa atgccacttg atctagcagt gatgggcgga
    12241 aacaaagcgg ataaggtcaa agaagatttt ccaaattccg attatgtgat cggtggccat
    12301 tcattaggtg gcgtaatggc aagtcgttat gtcaataaga atcattcaga caaacattta
    12361 aaaggggtat tcttcatggc aagttatccc gacaaaaaag gaacattgac agaatcagct
    12421 gttcctgttt tatcgatcac ggcgacaaaa gataaagtat tgaatcagga agcttatcaa
    12481 gaagctaagc agtatttacc ggaaagaaca gagtatgtat caatcaatgg cggaaatcat
    12541 ggaggttttg gcagctatgg tgagcaaaaa ggagatggag aggcagaaat ttctaacgca
    12601 gaccagcaaa ctgtgatcgt caatacattg gaaaactggc tgaaaaagtt gaaataatat
    12661 aaatgggtcc tatagggtcc gtgaaaaaac tagtcaatta actatagata gcaaatgaat
    12721 ctttcaaaat aagtcgggat ttcacggaac aagagaaaca gatcccggct tattttcaag
    12781 tttagagaac ttagtgtacg tttttaaagt ttcgtttata tttatatttt attttctaat
    12841 aaaatcgctc gaactggaca tttttgatac gcttttttta catatgtttc ttcttccggc
    12901 atcacgaact gttgatgagc ctctggttct tgggcaaata aaacgattcc ttcttcatca
    12961 taatcgaaaa tatctggcgc ttcgatttga caaagaccgc atgcaataca gcgttcaggt
    13021 acaagtttac atagtagtga catttctaac catcctaact taaggagaat aatatgattg
    13081 tttttatttt atcgctattt tcatcaggac acaagctgcg gattagttct ctttaccaac
    13141 tccttgtggg aaaacgaacg acttcagtac ttatttatgg atttacccac gaacttttgt
    13201 ttatccataa cagttttcca gaattgaagc aggataagtt ttatcaaatt ttgcaaaaaa
    13261 ttgcgcagca aggttggatc gaaataaatg aaaatgaagc aaagctaacg cctgcagggg
    13321 ctgatatgtt gtccgaacat caaatagaac atactggttt gcgttttgac cgctatggca
    13381 gaacagggga aactagttgg cggctcatta aatttgctgt tcaagtaatt tctaatctgg
    13441 caacgggtat tcaagactat cttccagcag agacaagtcc tttttatact ttccaactaa
    13501 aaaaatggct tagtgaaagc caattgccac gtgaaatttt aattgatact gcgtatgaga
    13561 gtttggtgca gctgttttcg gagataccag aagaagcagc agatttttta gctaaccaat
    13621 tatctggaaa tgagcgaaca gggctgcttc cttatcagct ggcaaaaaac aatgatgagt
    13681 cagaggttta tctgcaacaa agcagatgta tccacctttt gttagcacaa atcgaaaaac
    13741 ggccagattc gctttggcac gctttgatcg attcattatt acagcaaaat ttcaatcaaa
    13801 gcatgatgat caccaagcag atgtttatga atggtcagac aattgaccag atcatggcaa
    13861 tccgtcattt aaaaagagga acagtaacag atcatcttat tgagtgggcc ttgttttttg
    13921 atgattttcc atacgagtgg attctctctg cagaaacaat cgaacgtttg gaaccaaata
    13981 aggattccgt gcgagagtgg cgctttagcg aatggaatgt agatggacaa ttagattatg
    14041 gagaatttcg tttgtatcaa atctatctat tgagaaagga agcgatacag aatgttaata
    14101 aatgaattaa aaaaatattt tggatttgat tcatttcgtc ccggccaaga agaaattatt
    14161 caggcgttgc ttgatggaga agatactctc gctattttgc ctacaggaac gggaaaaagc
    14221 ctttgctatc aattgacggg gtatttaatg gaaggtctgg tcatcatcgt gtcaccgctg
    14281 ctttctctaa tggaagatca agtgacgcaa ttacaaaaac gaggggagaa acgagtagct
    14341 gctttcaata gtttactttc gcaatctgaa agaagatacg tcctccgtca tctatcgcaa
    14401 tataaatttt tgtttttgag tcccgaaatg ttgactaatc cttctctttt agagcatctg
    14461 aaaaaacaaa atattgcgtt atatgtagta gatgaggctc attgcgtgtc tcaatgggga
    14521 gttgatttcc gtccagaata tcaacagtta ggaaaaatcc gaaagctttt aggaaacccg
    14581 gtcacactgg cactaacggc gacagcaaca gatttagtag caagagatat acgtcatgta
    14641 ctatttgatc gaccaccaaa agagatcaga caatcagtca atcggcaaaa tatctcgctt
    14701 tttgttcgga aaacgcagca aaaagaacaa gaacttgaac acttcatgga aagagcacaa
    14761 ggagcggcaa tcatttattg tgcaacaaaa aaagaagtcg aacgattgta tcatttattc
    14821 agggaacgtt ttacagttgg atactatcac ggtggtcttg atgcagctca aagaagacaa
    14881 cttcaacagc agtttgtaaa aaatcagctg cagtttctca ttgctacgaa tgcatttggt
    14941 atggggatcg ataaatctga tatccgttat gtggtccatt atgatttgcc agacagtcta
    15001 gaaaactatg tacaagaaat cggtcgagca ggcagagatc aggaagaaag tgcagcaatt
    15061 cttttttatc aaagtgggga tgaacgtatc cattatttct ttaatcaact ttctagagaa
    15121 cagcgacaaa gttttgagct ttatttggaa tatgccacaa agcaagctcc ctttgatgag
    15181 ctgcaaaaaa aatggatgga gctgatccag cagtctgaaa aaccagaaaa ttgggtggaa
    15241 cggctcaaac gtcaggaaaa agaaaaagaa ttccgcctgc agcagatgct tcgctatatt
    15301 aatgaagaaa actgccgcag aaaattcatc ttagcttatt ttggcgaaaa actctccgaa
    15361 aagccgcaga attgttgtga tattgatgga gcaaaagcag aacttctgcc aaagaggaag
    15421 cttttttcta agactgaaca acttcattgg gaaacgattt tactaaattt atttaaaaaa
    15481 aacatggaac attgattttt taggacaaga cactttttcc tatggtataa tacacacgat
    15541 agagtttagg aggtaaaaca gtgagcagaa aagatagaca tcaatctaca gaaaataacg
    15601 aaacacaaga accatgggaa caaccaatct acgatacaga tgatgaagtt tcatcaagaa
    15661 gttctcagag acaacaaaag aaaggaaata cattatttct ttcgctattt ttgattttac
    15721 tggtcttatg tatcgctatt ccagcaggtg cttatttctg gatcagaaat ggatcaagca
    15781 acaatgcaac agcagcaact tcttctgaaa cttcgacatc agtagtagaa agttctacaa
    15841 gtacaacaaa agaggagtca actgagactt caacagtaga atctagtaca atcgcggaag
    15901 aatctactgt gtctcaagat acaggtgtaa cgtcagaaag cagtattgca gcagagacaa
    15961 caccgacttc ctcaagtgag gcaacttatc aagcagggga ttcaagcagc aatgcagcag
    16021 aaacaacacc ttcttcatca gctgcagccg gttcaacaac gactgttcaa gcaggcgaag
    16081 gtccaaaaca agtggctgag cgtgcaggga tcaccactga tcaattgttt gaattgaatg
    16141 gcttagatcc aaacaacttt atgctttacc ctggtcaaga attaagaatt aaataataat
    16201 agccgcgctt tgcggctttt tttctgagaa aaaggagtta tatcatgaca caaatcagta
    16261 ttgcaatcga cgggcctgct tcatctggga aaagtaccgt tgccaagata ttagcaaaag
    16321 aattgaatta tatttataca gataccggtg ccatgtatcg cgcagtaact tatttagcta
    16381 ttacgaacaa tgtatctttt tcagatgaag aagggctagt ttcgctgatc aaaaagtatc
    16441 ctatctcttt ttcgcaacaa gaagatggac agcatgtatt catagcatca aaagatgtga
    16501 ctttagaaat ccgtcaacca gatgtcacaa aagctgtttc tgaagtctct gcacatggaa
    16561 aagtcagaga agaattagtt gctgtccaac gaaaaatagg ggaacgcggt ggcgttgtca
    16621 tggacggaag agacatcggg acagctgtat taccgaatgc agaagtgaaa atctttttag
    16681 tagcaagcgt aagtgagcgt gcagaaagac gtttcaaaga gaaccaagaa aaaggaattc
    16741 cgactgatct tgaaacactg acgaaagaga tacaggaaag agaccattat gattcaacaa
    16801 gggacgtctc tccgctgaag caagcagagg atgctgttcg tatcgatacg actggcaaat
    16861 cgattccaga agtcgttgca gcaataaaag ctgttgtttt gaaaaaaggt tatcttcttt
    16921 tttaaattaa gaaaaaaaat gaaaaacaat tgttttttca aggaaaacga acgaaatcgc
    16981 tttatttttt ttgaataatc aattaaacta aaaacagtac cgtacttacg gcagaatgtt
    17041 ggttaggagg acaagtgtta tgacagaatt tgatcaaaat caagagaaca accagtcaat
    17101 ggaagacgca atgaaaagcg tacaagaagt aaaagttggc gatgttgtta agggcgaagt
    17161 tttagtcatt gaagacaaac aagtgattgt cggaatcgaa ggggctggag ttgaaggagt
    17221 cgttccggca aaagaattat caactttgcc ggtagaagat atcagcgaag tagtaaaagt
    17281 cggtgatgta ttagatttag tcgttatcag tacgatcggc aaagataaag aaaacggcag
    17341 ctatctactt tcaaaacgcc gtttagatgc taaaaaagtt tgggaagata tcgaaagaga
    17401 tttccaagag ggcaaggtca tcgaagcacc tgttacaaat gttgtcaaag gcggtttagt
    17461 cgttgacgtc ggtgtacgtg gttttgtccc tgcatcaatg gtggaagatc attttgttgc
    17521 agacttttca gactataaag gcaaaacatt gagctttaaa atcatcgaaa tcgaaccatc
    17581 agaaaatcgt ttgatcttat cgcataaagc ggtagtggaa aacgaaagag aagaaaagaa
    17641 aaaagaaatt ctttcaacta tccatgaggg agatgttctc agtggacgtg ttgcacgtct
    17701 tactgatttt ggcgcatttg tcgacctagg cggaattgac ggtctagtcc atgtctcaga
    17761 gatttcacat agtcatgtag caaaaccaag tgatgtattg gctgtcaatg atgatgtaaa
    17821 tgtcaaagtg ttgtctatca atcctgaaca agaacgtgtt tccttgtcaa tcaaagacac
    17881 acagcctgga ccttggtcag aaatcgatac aaaagctcca gttggcacag tattagacgg
    17941 aacagttaaa cgtttgacaa gcttcggtgc ctttgttgaa gtgttccctg gagtagaagg
    18001 gctagtccat atctctcaaa tttcacataa acatattgcg acaccacatg aagtgcttca
    18061 tgaaggtgac gaagtgaaag tgaaagtatt agagatccat ccagaagaac atcgtattgc
    18121 attgagtatc aaagctttag aagaaaaacc agcttcagaa gaagaaccaa aaaatgttga
    18181 gtcttatgaa ttaccagaag aaaatactgg atttactatg ggagacattt taggtgatgc
    18241 gttgaaagaa gaagtagaag aaaaagcaac cgatgattct gaaaaataat tgattttgta
    18301 tctgtgactg agatgaaagc agctgctttt gtctcagttt ttcttttgaa aagcgattag
    18361 tatttcaata aggaataaaa atacttcgtt taattgacaa tctatgcttg aaagttggca
    18421 atgcattcgt taaactaagt gagattggaa acttgtgagg aggaaataat atggcaaatc
    18481 caacaattgc aatcgttggc cgcccgaacg tcggtaagtc tacgattttt aaccgcatcg
    18541 ctggtgagcg tatctcgatt gtcgaagata ctcctggagt aactcgtgat cgtatttatg
    18601 caaaaggtga atggttaggt cgagaattca gcgtgatcga cacaggcgga attgatcttg
    18661 gcgatgaacc ttttatggat cagatcaagc atcaagcaga aatcgcgatt gaagaagcag
    18721 atgtaatcat ttgtgtagtc agcggacgcg aaggcgtgac agacgcagat gagatggttg
    18781 cgaaaatttt atacagaagt aataaaccag tgattttagc agtcaataaa gtagataatc
    18841 cagaaatgag aaacgatatc tatgaatttt attccttagg gctaggcgat ccttatcctg
    18901 tttcaggaag ccatggacta gggattggtg atattttaga tgaagcagtg aagtatttct
    18961 ctgaagagac tgaagaagag gacgacgaca cgattaagtt tagtttgatt ggtcgcccaa
    19021 atgttggtaa atcctctttg atcaatgcga ttttaggaga agaacgtgta attgtttcgg
    19081 atattgaagg aacgacccga gacgcaatcg acacccactt cgtttctgaa agtggtcaga
    19141 aattcttaat gatagataca gctggtatgc gtaaacgcgg aaaagtatac gaaaatactg
    19201 aaaaatacag cgtgatgcgt gcaatgcgtg ccattgaccg ttctgatatc gttttgatgg
    19261 tactgaatgc tgaagaaggg attcgggaac aagacaagcg agtagcgggt tacgcccatg
    19321 aagctggtcg tggaattatt atcgtcgtga ataaatggga tcttgtaaag aaagaaacca
    19381 atacaatgcg tgatttcgaa caagagattc gtgatgaatt ccggtatctt gattacgctc
    19441 caatcgtttt tgtttctgca gtgactaaac aacggttgga acgtctgcct gaaatgatcg
    19501 aacaagtaag tatgaaccag aatcttcgta tctcttcggc tgtgttgaat gatatcatta
    19561 tggatgctgt agcaatcaat ccaacaccaa cagataaagg aaaacgcctg aagatttttt
    19621 atgctacaca agtcgctgtc aaaccaccta catttgtcgt ttttgtcaat gaagaggaat
    19681 tgatgcattt ttcttatgaa cgtttcttag aaaatcaaat cagaaaagca tttacttttg
    19741 aagggacgtc catccgaatt atccctcgta ggagaaaata ggcattttac catatcgacg
    19801 tttttttttc aaaagaaaaa gacagtttcg tttgttacgt ttctatgact aaaaaaagca
    19861 tgtgaaaatt ggtaaaaacc ttgctattaa gcggttcata tgatatcgtg ataacagaat
    19921 attgaagtta atcaatattt ctttttaaac ttctggacca ctcagaaagt tttaactaaa
    19981 tgatatttct atcatatctc ttgtggagga ggtgaatcta tccatggcaa acaaagcaga
    20041 attaatcgaa aaagttgctt cagctactga tttaactaaa aaagatgcaa ctgcagcagt
    20101 agatgctgta ttttcaacta ttcaagatgc tttagctaac ggcgaaaaag ttcaattaat
    20161 cggttttggt aactttgaag ttcgcgaacg cgcagctcgc aaaggtcgta acccacaaac
    20221 tggtgaagaa atcgaaattc cagctagcaa agtacctgca ttcaaaccag gtaaagcatt
    20281 aaaagacgct gttaaataag acagttgaaa aagcgcttgt ggctctaggg ctacaagtgc
    20341 ttttcttttt atttcctagc agaaaaggaa taaataagag acagagattc cgaatccgta
    20401 tgtcatacat agaaaacaca tgtattttat ttaattttta tttatttgca agttatgagg
    20461 tgagctttgc tcttatcttt tctagaattt gcttactaat ggtaaaataa aaataagaag
    20521 aggagggatg cgtatggaac ttgattatca agtagaagat gcgttgacga aagtgtttta
    20581 cggagaaacg ctagtcagtc agctaagaga actttccatt gatcagccaa tcttattttt
    20641 aacgaatcag cgctattatg atttgtttgc agataagatc aacccgttat ttgcaaatca
    20701 agcaaacaat gactggtata tttgtgccaa cactcaatgc aatcatttaa cagaattaaa
    20761 gaacctgctt gatttcgtca aacgctatcc cgaaaatcaa tccatgttta tcatcggatt
    20821 tggaaatgaa gggatcatgg atctggcagg tttttttcaa aaacatacaa cccttgattc
    20881 atcactatgg atgatccctg tatcgatccg ttctctaagc cgagcattaa caccgcagcg
    20941 gacgattttg cagctaccaa atcgtgtagt gctgcaaacc atcaatctgc cagaacgcat
    21001 cgtttatgat caaacaatca gcgagcggca ggtggacgga aagcagattg actttttgac
    21061 ttttatctgt tgcggaatga tttgtgatca tcgttttttg caaaatctgt ataaaaacta
    21121 tccaaataaa aagcaattaa cgactcggcc gtttgccggg atgatcgaag aaatgatcta
    21181 tttttatcaa ttagaggcag aaaacctgtc aaattatggt aaactgtttg aacaagcttt
    21241 ttatctgacc gaaaatggcc atctactttc tgctagtatg aaaaaatttt taggaatgat
    21301 gtttcatttc gtgtggaatc tccaagcata tccttttgat ttccaactaa aaaacttttt
    21361 tgtgtggctg gacttgcttg gctatccaat ccactggctg gaacagattt caaagatgga
    21421 gtatttggaa aaagttcttt ttttggcaga aaaaagcaaa aaaatacttg ttttagaaaa
    21481 aataggtata atagacggat accaacatcc aaacgaaaaa gaattattga gaacaatgac
    21541 ggtatttcaa caaatcgtca gtgagataag agggaattga aatgaataca aatagcgaaa
    21601 aaatgttgca agctttatca gatgaagact tgtcacaagc acaaatcttt ttagaaaaag
    21661 cattaaaaga agacccagca gatatattag ctgaactagg cgaagaattg ctggctattg
    21721 gctttttgat cgaagcaaaa cagatttttg aacaactgat caaccaatac ccagaaaatg
    21781 acggactgaa catcccgtta gcagaaattg caatcgaaga taatgagatc gacttagctt
    21841 ttgaatacct ggaaaaagtg gataagcaaa gtgattacta tccgcaaagc ttattggcga
    21901 tagctgattt gtaccaagtt atcggaatcc ctgaagtgag tgaagcaaaa ttgaaagaag
    21961 cagctgggtt gcttcctgat gaaccattga tccagtttgc gctagctgaa ttgtattttt
    22021 cagttgatcg tttcaaagag gcagcagtgg tttatgaaac attgttggca agcgggataa
    22081 atgaaatttc aggaatctcg atgcaggaac gtttaggaca atccttaagt atgcaaggag
    22141 aattcgaagc agctatcgta cctttagaag aagcactgaa agaagaaagg acagatgatc
    22201 gactgttcca gctagctttt acgaatcttc aattgaaaga aaatcagcag gcaatcaact
    22261 atctggaaga acttcgagaa gttaatccgc attatcaatc gttatatcta tatctaggac
    22321 aagctcttca agaagaagaa atgattgaag aagcacaaac agtgttagaa gaaggaatca
    22381 aagaaaatcc ttaccaagtc gaactttatc acctggcctc ggaaaatgct ttccgtctgc
    22441 atgatagaca gcgagcagaa gaacttttac tgaaagcttt agaagtagga gacaaacaag
    22501 atgaaacatt acttacttta agtaatcttt acttggatga tgaaagatat gaagatgtga
    22561 tacaagtgat caatcagatg gaagaaactg ctaatcctta tgcagaatgg aacctagccc
    22621 atgcttataa tgaattagaa gactttaccg ttgcagctgt acactatgaa caggcttatc
    22681 atgaactatc acatgaacca gatttcttga aagagtatgc ctttttctta agagaagaag
    22741 ggcagctgaa aagagcgcaa gaattattga cttattattt aacacttgaa ccaggagata
    22801 tggaggcact gtcattatta gatgacctaa cagagaggtg agaaaaatgc taattgatgt
    22861 acgggaaaag aagaattttt taacgtggat ggtcaatcat gtatctttta gccgaagaga
    22921 agttttttgg atcttgaatt atcttgccaa tcatgaagcg attttaagca atgtccactt
    22981 tgttgaaggg gcgaattttg cggatcgagg actgcagatc agtgatctat ctgttgaagg
    23041 ggaacccatg aaattgtttt tgcagggaaa agaatttacg gacacagacc agatttttca
    23101 tgaaatccgt ttgaattgga aaaagccttt atatgtggaa tgtatattcg aaaatgcttg
    23161 gcagacaaga gaatatctat ctatcttaga agacaatcca ttttcttctt gggattcttc
    23221 agtcagtgaa gaagatactg aattaattga acgatatttt caagaaaaag aagaagaggc
    23281 aaaactaaaa atgctttatg ctcaaatcga tcaagcacta gaagatggag atagggatgc
    23341 ttttttgaaa ttatctgatg aagttaaccg aaagatcctt ttgcagacac aaaagaaaag
    23401 taaccgggta agtgaacata acaattagtt aaaaatagta tagtactaaa aaagacaaag
    23461 gtcagctgga tgtggaatct ttcctcatag cctatctttg tcttttttct tatagttttt
    23521 tcagtaatct tgtctgtggc ttcaaataag taaagccttg cccttccact tcatgcacat
    23581 tgatgattga aaggaaagct ttttcgtcaa tctcgtggac gatcctctta gcttcagtta
    23641 attcactaga gctaacgacc atatagatga ttttttttga attaccagag aatgcgcctt
    23701 ctccagaaag gaaagtcaca cctctttgca gaccggtcat cagtagtggt gcaatctctt
    23761 cgcttttgtt ggagacgaca agtagacctt ttgcagaata tccgccatct aagatcgaat
    23821 caatcacacg actgaaaaca tacgaaacaa tcaacgtata catcatacgt ttcaagtcga
    23881 tataggttaa tgaagcaagt aagacgatga tatcaaatgc caatagggaa cgccccatag
    23941 tgatgccgta attttgttct aaaatccgag cgataatatc actgccgcct gttgttccac
    24001 ccatgcggta gacgatcccg cttcctacac ctgcaactaa acccgcaagt agagaaacga
    24061 tcagtagatc atgctgtaaa ttgatttcta gtggaaccct ttgccagatc cataaaaaga
    24121 atgacaaaga aagtgtacct agaacagtat aggccaagga acgtttaccg aggatctttc
    24181 ctcctagtaa aatcaatggg atgttgatta ataaagtcgt ataagctgga tcaataccaa
    24241 ataaagctct taagatcaag gtgatccctg agactccccc ttctgctaaa tgattagcga
    24301 tgttcaagta aacaagacca aatgcataaa tacttgttcc tataatgata aaaagaactt
    24361 cttttactgt ttttcgtttg accatatgaa ttccagcttt caattatgta ttttcacaga
    24421 atttccattt agaaattcct tcctaaatgt agcatggaaa ttcgattttc tcaattgctc
    24481 ttatctagga tttgcgttaa agttttggta agatagtttt ggagggaaaa agatggataa
    24541 aaagcgttct ttatacagta tgcagcagga agtggatgaa tatatccagc aattcaaggt
    24601 ggggtatttc tctccattag ctcagatggc tcgattaact gaagaagtag gtgaattggc
    24661 aagagaagtc aaccacactt atggagaaaa aagcaaaaag gcttctgaac cagttaactc
    24721 ggtagcagaa gaacttggtg atgttttatt cgttacgatg atcatggcta attcattgaa
    24781 tatcgactta actgaagttt ttgaaaaaaa catggaaaaa ttcaatcaaa gagaccataa
    24841 tcgctttgag cgtaaggacg agtaaacaag atgaagtggt cctggccttg aagactctga
    24901 aacggacttg tcaaacagtc accatgcaac tgagtcttta tctcaggaca agaaacacgc
    24961 aggaaaggtt ggaaaaatga aattaaaaca attacctctg gaataccaaa aggcaattcc
    25021 agttctgaaa aaattagaga atgcaggata tgaagcttat tttgtaggtg gaagtgttcg
    25081 tgatatcttg ctgaaccagc caatccatga tgtggatatc gcaacaagcg catttccaga
    25141 agaaatcaaa cagctttttc caaaaacgat agatattggg atcgaacatg gaactgtgtt
    25201 ggtattagaa aatgatgaac aatatgagat caccacattt cggacggaat caacttatca
    25261 ggactaccgt agaccagatc atgtcgaatt cgttcgttcg ttggcagaag atttgaaaag
    25321 aagagatttt acgatcaatg cgtttgcttt gaaagaagat ggagaaatca tcgatttgtt
    25381 cgatggtctg caagatctag aagaacagat cttgcgagct gtaggcaatc ctcatgagcg
    25441 gttccatgaa gatgccttac gaatgatgcg cgggttgcgt tttgtcagtc aactagggtt
    25501 caaattagag gaagaaacct tctacgccat caaagaaaac cacgagctat taggtaaaat
    25561 atctgtagaa cgtataaatg tggaattcat caagatgctc ttgggaaatg aacgggccgc
    25621 gggaatccat gcatttattg aaacagagtg ctacatttgc tgtcccggtt tgaaagaaga
    25681 aggcgaagca cttttacgtt ttgctgaatt accatccgtc ccattgaaag aagagagcca
    25741 agcatgggca ttattgatca gccaactgga tctaaaagaa aatgagattc gttccttttt
    25801 gaaatcgtgg aagtgttcta accaaatgat taaagacgtt caagcacttg tccaaggact
    25861 acgacaacga gaaactggag ctttggaacc attcgaattg tacttcttag gcaaaaaaca
    25921 tgcactgcaa gtagaagaat tgatgatcta ttttgacgaa acacctcaga tggatgccgt
    25981 aggagaatcc tatgatcgtt tacctatcaa gtcattaagc gaattagcag tagatggtaa
    26041 aatcttgcta gaagaaactg gaaaaaaacc tggtaagtgg gttagtgaag ctttgcaatt
    26101 agctgaaaaa gccgtcgtag aacaaagaat aaaaaatgat aaaaaacagg ttttggattt
    26161 tttatcgaaa gaaaaattga tttaaaaaac actagactgt atctgctcag ctttgttggc
    26221 tacttaaagt gggcagatac gtcattagaa gaaaaaacat aagatgtgac cacttacata
    26281 aatttgtgct aaactgaggt agtacaagaa taaattacat cataaaggag tctttttaat
    26341 gagtaaagaa atgacagcgc taaaatttta ttttagaaat ggagaaacct ggacgatcaa
    26401 ccgccgtcat atcggcgatc tttggatcaa acaaatcaca acaagttttg gacgaatcaa
    26461 tggcagtgaa tttgttgaaa tccatccgtg tgctggattt aaaatcgaaa tcttccatga
    26521 aggggacgca gttgcgacac atgatatcaa cctaggcgga ctggaaatgg gcatgtttaa
    26581 tcgcgcattg aaatacgaag atatcgagcg aatggaaatc ctttaccgaa atggcacacc
    26641 tgatcttgtg tacttcccat atctagataa aggaacagaa ggattagaca atcaatatca
    26701 atcaacaaaa atcagcgaaa aaacaggtaa cttgtatatc gtgatcaatc cagatcaacg
    26761 tgtagaagat gtatacgggg aatttttcga ataaatcgat ttttacgcaa aaatgaggct
    26821 gtgaaagaga tgtgtcttat tactactgat aggctgtctc ttccacaccg tttattcaga
    26881 ataagggact gtgacaagat ttttgtcgca gccccatttt tttgttgtga taaaagaaca
    26941 agaaaggcag gaatgggaaa gtaaacatcc ttttgtcaga aacttttatc tttcttaagt
    27001 tttacttgat atctgatact atttggaata gaatgaggcg ttgaaaaatt tatggaaatt
    27061 tctaactagc aataaacgat gaaacaatga aatatttttc atccaaaaag aactttgcta
    27121 taatgatgga agtttgtgta taggagatct ggaaaatgag agagagtttt gaacaacaaa
    27181 aaaaactgtt gcatgatcgc tatggcgccc tttcgatgga tgaccgccgt caaatacttt
    27241 gtaagttgcg taaaagaaat atattgatgt atcgtcagtt ggaacgtctg aaacatgatc
    27301 tgcttcgttt ggagtcaaaa cgtgtacagt gtgaattaga ggggaaccaa acacaggttg
    27361 aagtagtcga aaccaaaatt ttaaagaaaa aagaacaatt tttaaaaatg cttacacaaa
    27421 ataaaaaata aaggggatgg acgatggaat ttgctgagtt agttattgta tttgcagtaa
    27481 cgatcacctt atcgaacata gctagccgca ttttgccaat gattccagct ccactgatcc
    27541 aaattttcct tggagtggta ttaggtctga cagagtgggg acaatcaatc gattttgaac
    27601 ctgaattgtt cttagttatg attattgcac cattgttatt tagagaagga gaaaaagcag
    27661 atatttcttc gattctcaaa aatttcggga caattttgtt cttggcattt ggaggagtca
    27721 ttttgaccct tgtcggggta ggtgcgacgt tatcattcct gttgccaagt gtcccacttg
    27781 ctgcctgctt tgcttttgga gcagcgttag gtccgacaga tgcggtagca gtcagttctc
    27841 tttctggacg agtgaatatc cctaaaaagg cgatgcatat tttggaagga gaaggtcttt
    27901 tgaatgatgc atctggtgtt actgccttcc agtttgctct tggtgcgctg atcaccggat
    27961 ctttttcagc agtaaacgcg gggatgagtc tagtagtttc tagtattggg ggagctttga
    28021 tcggcttttt gcttgtctgg ttcaaacaaa aaataattca tttgatcgaa aaagcatcag
    28081 cacaagatgt cacagggtat ctgctgatcg aacttttgct tccttttcta gcctatgtat
    28141 tggcagaggc atttgatgta tctggaatca ttgctgcagt ggcagcaggt attctccaag
    28201 cttctggttt taggaaaatc tctgtgtttg atgcagaatt gtcgagcttg tcccacagta
    28261 catggacaac tattgctttt acactgaatg cattagtatt tatattttta ggaatcgaat
    28321 tgacgcaagt gttctcgcca gtatggggag acggtttata tccaaacggt cttttattag
    28381 cgattatcgt attaatctct gtcatgcttt ttgtgatcag attcatttct atcagtcttt
    28441 tttatgtatt caaagatggc agtaaaaagt tcaaaaaaca gttgaacgag atcttgatct
    28501 taacatttgg cggtgtaaag ggaacagtca gtttggctac gatttttatt ttgccatttt
    28561 caatcaataa tatgatgttt taccagcggt ctttgctttt gtttctgacg gcgggtgtca
    28621 tcttagtgac tttggtcata gggatcattg tcttgcctat gctgacggaa acagaggaag
    28681 cgaaaagcac ggatttgaat gctttgatga ttttagaaga ggtcgttgaa gttttgcgaa
    28741 aagaaataaa ggaaattgat cgtaatacaa aagaattttt agccactgaa gcagtgatag
    28801 aaaattatca agaacggata cgtgatctgt acttggaaga tttaaccgat gatgaaaagc
    28861 aagaagtaca agaaatacaa gcactgattt tgtcgatcga acgggatgga ttggatgaaa
    28921 gttatcgttc gggcaagctt tcttctaatg gttatcgttt ttactcccgt tttctttctc
    28981 gattcgaaca ttctatcaca agccagattt tgtcttttat cggcttttgg ttcattgttg
    29041 tccgtaggtt aatgcgaatc gttctccatc cgaaaatgtt ttggcaaaga agatatgctg
    29101 atcgtcagac atttattagt gatgaagata tccaagaaat cagagagaca tatcaaaaaa
    29161 atactcagtt gattattgaa agtttagata acttgactga tatttatgat gaaacgatgg
    29221 ttcaattttt tatccagcaa cgcaaacttg aaggaataaa aatgaactcg gggaatttga
    29281 tttcttcgtg gatgatccag caagatagtc tgtttacgaa aaaaatgcta agaggttatt
    29341 atcttgaaag aaaaatcatt gatgaatacg aagttgctga aaaaatcacg acgttttctg
    29401 cgaacagcta tcgcaggaat atcaatttgt tagaatctta tacgatgaac aaaccatctg
    29461 ataacttttc tttccgattt gcgtttcgag caaagtcaaa aaaaacgagt ccaataaaat
    29521 aaaaaggtaa aaattttcaa gttttataaa aaacaaaaca tatcagaaca ggatcgaatc
    29581 ggtcctgttc tttttttgag aacacaaaaa gaacaaatac caaaaaaatt ttcctgaagt
    29641 tcactatttt tatgatacaa tatccaagat aaggagggaa catgttgaaa gaattaaaag
    29701 taactgacct caaaaaaact tatggtgaaa aagatttgtt tgaccagatt tcttttttgg
    29761 tccacgaaaa agaccgtatc gggttgattg ggacgaacgg gacgggtaaa acaagtctct
    29821 taaatattat tgccggtatc gatagcagcg acggtgatcg gcaaacagtg ttttatccaa
    29881 ctgattaccg tattggttat ctttctcaag cagctgaatt ttccgatgaa ttaactgttc
    29941 tccaagcagt ctttcaagga aacagcccct tgatccaaac tgttcgagca tatgaggaag
    30001 cattgatcga actaggggaa aacggagaag accctgatgt gcaaaaacgt tatgctaaag
    30061 cagaagaaca aatgaataaa gaagatgctt ggactacaga taccaacgca aagattattt
    30121 tgcaaaaatt aggaatcagt gaattagata aaaaaatcag tactttatca ggtggtcaga
    30181 aaaaacgagt tagtctggcg caagtgttga ttgatgaacc cgatttacta ttactagacg
    30241 aaccaacaaa ccatttagat tatgaagcga tcgagtggtt ggaaaactat ttgaaacaat
    30301 accgtggcgc actattgatg gttacccacg atcgttattt tctagataga gtagcaaacc
    30361 gaatcttcga actttcattt ggaaaattat acgagtataa aggaaattat gaagcttacg
    30421 tcttagaaaa agcagaacgt gatcgtgtag aagtagaaca agaagaaaag cgcaagcggc
    30481 tttataaaca ggaattagct tggatgaggg ctggcgtaca ggcacgtggc accaagcagc
    30541 aagcacggat caaccgtttc gaagatctaa aggagaactt gtaccaagta aaccaagaag
    30601 atgatttaga gctgaaccta gcgacacaac gtttagggaa aaaagtactg gaaatcaaag
    30661 atggcagtta ccgtataaat gaccaaacac tgctagaaca tttagattta ttgattcaat
    30721 ctcgggaaag actaggtatt actggtaaaa atggtgcggg aaaatcgaca ttgcttaata
    30781 ttctagctgg cagaattccc ctggatagcg gtacaatgtc tatcggtgaa acggttcatc
    30841 ttgcgtatta tacacaagaa aatgaagaaa tggcaccaga taaacggatg attgcttact
    30901 tacaagaagc tgctgaagaa gcaaaaacag cagatggcag tcaaatcgga gtagcagaat
    30961 tacttgaacg atttttattt ccaagattta tgcatgggac actgataggc aaactttcag
    31021 gcggagaaaa acgccggtta tttttgttga aactgctgat tcagcaacct aatgttttat
    31081 tattggatga accgaccaat gatttggaca tagcaacatt gacgattttg gaagattatt
    31141 ttagaagttt tccaggtgct gtgatcactg tttcccatga ccgttatttc ttggacaagg
    31201 tagcagataa gttattagta ttccaaggaa acggaaaaca agaactttat tacggaaaca
    31261 tgtccagtta tttactgaag caaaaagaga cccagcagcc tgctgaaaaa gcgaaaccaa
    31321 aaatacagag caaggaacct gctgaaaaga agaaattatc ttacatggaa caaaaagaat
    31381 gggaaacgat tgaagatgag attgcagaac ttgaagaaaa aatctcattg ctccaagaag
    31441 agatgaatca tcaaggagat aatttcactc gattacaaga attgcaaaac gacgtatctg
    31501 aaacagaagc acaacttgaa gaaaaaatgg cacggtggga atacttgagt gaatgggtag
    31561 aagattagga ggaaaaagga tggaacaagc gtatcttgac ttaggaagaa aattgttgga
    31621 agaagggcat cgtaaagaag acagaacagg cacaggcaca ttaagcttat tcggatacca
    31681 aatgcggttt gatctgcaaa aagggtttcc tttgttaaca acgaaacgag taccttttgg
    31741 attgatcaaa agcgaattgc tttggttttt aaaaggagat acgaatatcc gctatctatt
    31801 acaaaataaa aaccatattt gggatgaatg ggcatttgaa cgctacatca aaagtccaga
    31861 ctataatgga ccagatatga ctgattttgg ccatagatgt ttgacagatc ctgaattcaa
    31921 tgaagaatat aaaaagcaga gcaagctttt ttgcgagaag atcctaaccg atgattcctt
    31981 tgctgaaaca tacggcgatc ttggacacat ctacggctat caatggcgtc actgggaaac
    32041 aaaagacggt ggctttatcg atcaaatcaa acaagtgatc gaagcaatca aaaagactcc
    32101 tgattctaga agattgatcg tttctgcatg gaatccggaa gatgttccta gcatggcttt
    32161 gcctccttgt catacgatgt ttcaatttta tgttcaagag ggacggctaa gctgccaatt
    32221 gtatcaacgc agtggggatg tgtttctagg cgttccgttc aacattgcaa gttatgcgtt
    32281 gctgactcac ctaattgcac atgaaacagg tttagcggtt ggcgaatttg ttcacacatt
    32341 aggagatgct catctttata tcaatcatat cgaacaaatg aaagaacaat tgagccgaga
    32401 aatacgcgca tttccgactt tagttttgaa tcaggaaaag cagtcagtat ttgattttga
    32461 gatggaagat atccaattag aaggatatga cccacatccg gcgatcaaag ctcctatcgc
    32521 tgtttagaat cagaaaggat gagaaaatgt tagctgcaat ttgggcacag gatgaaaacg
    32581 gattgattgg aaaagaagac cgtcttcctt ggcgtttgcc aaatgatctg aaattcttca
    32641 aacaaatgac agaagcaaat acactagtga tgggacgaaa aacattcgaa gggatgggta
    32701 gccgtccgtt gccgaatcgt cagacgattg ttttgacgag agattcttcc tataaagcag
    32761 aaggcgtgca tgtcatgcat agtgtggaag acgtgcttgc tctggaaaaa gaaacagacg
    32821 gtatcttttt catcgctgga gggtcagctg tttatcaaga atttctgcca ttttgtacga
    32881 tattataccg tacagtcatc catcatgtat tcgatggaga tgcttatttt ccacctgttg
    32941 actggtctga ttggtcactg atcaatacta gtcaaggaga aatggatgaa aaaaatcgtt
    33001 atccgcatca atttgaaacg tatcagcgta atgagaatcc tgtaaaaagc gggacaggcg
    33061 aattgacgat ataaaaaagc tatggataga ctagctgtta tttagagctg tcccatccat
    33121 agctttattt tttttattaa gtaaagaata aaacagagaa gtacataaaa cctgcaccta
    33181 acataacaaa caaatgccaa acaacatgca tatagcggat agaattcaag ctataaaaga
    33241 atgcgcctat cgtgtaagaa agcccgcctg ctaccatcaa aataacacca gtcattccaa
    33301 gagagtgata aagaggaaca gcagccacga cacagagcca ccccataaaa atatagatga
    33361 tcgtagatac ttttgatact ctctcccgtt tatgcaacgt caacgcttta tatataatgc
    33421 caagaatcgc aaacaaccag attaatacaa ataaagtcca acctagccat cctcggatac
    33481 tcagcaaaca aaaaggagta taacttcctg caatcaaaag aaaaatcgaa ctatgatcga
    33541 atacttggaa cacctttttt gcttttgtaa aaatcaatga atgaaacaaa gtagacgtta
    33601 aaaataaaag aatcatcatc gatccataga tagcataaga gacaatatgg agggaggaat
    33661 gcaagtgggc accttttact aaaagaacca ctagtcccgc gatactcaat ccagtcccaa
    33721 ttccatgggt gactgcatta aacacttcat ttaatatttc atacgttcga ttaaatttcg
    33781 ttttttccat gaaaacggct cctttactag gtgtaattaa tgaaaaatca ttatttgtct
    33841 gttatactaa aaatagaaat tgtcttacat gtagtttaac atgaataagg catcttgtta
    33901 aagaaagaga gagagaaaat aatgacaaat gtaaaaatcg taacagattc ttcatgtacg
    33961 atggaaaaaa atgtacgcga tgctttaggc attcgtgtca tgccgctatc catcatgatc
    34021 gacggaacag tatatcccga tgatgaccaa ctagacggcg aaagatttat ggaaatgatg
    34081 gcgaaagcaa aaaatctgcc caaaacaagc caaccaccaa ttggagaatt catctcgatg
    34141 tatgatgagc taggagaaga cggcagtgaa gtgatttcga tccatatgac aaaaggcttg
    34201 agtggaacag tagaagcagc aagacaagcc agtaatctaa caaaaacgaa agtaacggtt
    34261 atcgacagtg ataccactga ccaaggatta tcttttcagg taattcgagc agctgaatta
    34321 gcaaaagaag gtaaaacagt agagaaaatc cttgaagaag tcaaaaaagt acaagacaat
    34381 acaaaattat acatcggaat atccacacta gataacttgg taaaaggtgg aagaatcagc
    34441 cgaacaactg gtttgctgtc tagtgttttg aacatacgcg tggtgatgaa tttcgcccat
    34501 tctgaattaa tccctgtaac taaggggcga ggaaagaaaa cgttcgataa atggtttaat
    34561 aatttgaaaa atgaactgaa agaattgcca aatgtgcgac aaatcggtat ttcacatgcg
    34621 gatgcaaaag aattggcgca agaattcaaa gagggtttgc aagaattatt cccggacatg
    34681 catatccctg tactgcatac gaatccggtt atcgctacgc atactggtaa agacgcgttt
    34741 gcaatcatgt attatgtaga ttagtcgaaa agaggataag ccctcagcct gaaaggcttg
    34801 cagcttattc tctttttctt tataaaatta ggaaaataat tgttttcttt tttcataaag
    34861 actacctttt tgataaaatt tttgataaca ttagaaccaa tcgaatacaa gaggtgaaaa
    34921 aatgaaatta acgaaacgac atttgatcct cgttttgttc ccattattaa ttgcgatcat
    34981 catctatgca ggtttagctg cttctatacc gaaagctggc ccactaatga aaccagtaac
    35041 tactgtgaga gaagatccaa ataaaaaaga aaaacttcac tacatagcta tcggagattc
    35101 gctgactgaa ggagtaggag atcaaaccaa gcaaggagga ttcgttcccc ttgtcgcaaa
    35161 tgatctaaaa gaccgttata atttgaccgc ggttgaaaca gaaaactatg gtgtaaatgg
    35221 tgaacgaagt gaccagatct taaagcgagt aaaaacaaaa gaagaaattc gaaacaatat
    35281 caaaacagct gattttatca cactgactgt tggcggtaat gatttgatga aagttatcca
    35341 aaataattta ttcgggttaa cggtcaattc ctttaaaaag ccactgaaaa actatcagga
    35401 aaatgtcaca gaactattgg aagaatttcg atccctcaat aaaaccgcac ctatttacat
    35461 tttaggcatc tacaatccat tttatttgaa ctttcctgag atcactgaca tgcagacaat
    35521 tgttaacaat tggaacaaag gaacagaaac ggtgacaaaa aaaatgccga actgctactt
    35581 tatcccaatc aatgatttgc tttatcaagg attgaatcag gaagtaggtg tcacagaaga
    35641 aggaacagat caaacaacta gcacgacaga aaatctaaat ggcatcaaaa ataatgtgct
    35701 ctatgaagaa gatcatttcc atccaaataa tttaggttat caattgatgg caaatgcagt
    35761 gagagatcag ctgatcgaga cacaaaacca atggttagag aaggaggatg atcaataaac
    35821 atgaaaacaa gatctgacgt atcttcaaac aaaacaaaga aaacaaatta ctggaaattc
    35881 gccttcctta tccttcttgg ggtagtactt ggttcgaccg tatttttagg cagccgtatt
    35941 tttgctaatc gggaaccaga actcccagaa ataccagctc ttacggaaag acaaggagat
    36001 cctgtcttaa cgatcaattc aaataaagaa aaagtcaatc aaatcatcag ctttttcctt
    36061 agtgagtatc aaaaagatag tgatattgaa tataaatttt atttggaaaa tgaagcacta
    36121 ctcaatggta ctttcgaagt actaggtttt cctatcgatt tctatttata ttttgatccg
    36181 tatgtgatgg aaaacggaaa tgtccaacta aaagctagaa gtctttctat cggaacattg
    36241 agtttgccaa tcaaagatgt gatgaatatg atcaagagaa actataaatt accagattgg
    36301 atcgaagtca atacagatga tctgactatc atgcttaggt tggatcaatt ccgaatgcaa
    36361 aacgggatgt atattaaagc agataaaatc gacttagtaa atgatgacat tcggtttagt
    36421 ctatatttgc caaaagatac ctctgatgct tcaaacaact caaataccaa caaaactagc
    36481 accagcagta ctgaaagcaa gacaaaagaa aataaaaaat catcggatga gtagtattag
    36541 agggggaatc ataatggaac gagcaatatt tgcaggaggc tgcttctggt gtatgatcca
    36601 gcctttcgac acgcttcctg gtatccatac agtgatgtca ggatatactg gagggcatgt
    36661 accagatccg acttatgaac aagtaaaaag ccaaacgact ggacatacag aagcagtgga
    36721 gattatctat gatccaacat tgatttcata tgaacaatta gtagaacttt actggcagca
    36781 aactgatcca actgacgctt tcggacaatt cgaggatcgc ggtgacaatt atcgcccggt
    36841 gatcttttat ttgacagaag aacagcggat cattgctgaa aaaagtaaga aacagttagc
    36901 tgaaagtgga cgtttcgaac agccaatcgt tacaaaaatc gaaccagccc aaccatttta
    36961 tctagcagaa gaagaccatc aagagtatta taaaaagcat cctgaaaatt ttaaaagaaa
    37021 ccatgcacgc cgggctgcct ttatcgaaga aaattggagg aacgaagggt gaatcgaagc
    37081 ttttttcatt atttaatgac actgcgaggc ggtggcacac atgatgcttt atctgttttc
    37141 gctacagaag ccggtaaaga catccaattt cctaagcaca gctctagcta cgaagaaatt
    37201 tctaattatc tggaactgaa tgtcgactat ttgccgtcca tggatatctt tgacgaagca
    37261 tgggaaaaat atttagaaaa taatcatgac atataagaga tagttttgta ctttatgatc
    37321 aaaaaagttt tttgtccaat agcctaattg aaagaattat ttttatttca gctatctagt
    37381 cgcatttttt tgatattttt cttataataa agaaagaatg aaaaaaagag ggatggattg
    37441 atagagattg acaaaaaaac aacgctatat taatcgcttc tggcttgtat tcaaatactt
    37501 acttgtttct gtattccttg cgttcatgtt gcggggattt ttattcatcc cggtaccagt
    37561 ggaaggcaat tcaatggaaa acgtgttgaa gcaaggtgat atggttgtga tggaaaaatt
    37621 ttcggagatc agacgatttg atattgttgt ttttcaatta gcagatggca cgatttatat
    37681 caaacgagta atcggtcttc caggagaaaa tgtcagctac caaaatgatc aattgaagat
    37741 caatgggaaa gtagttaagg aaccttatct aactaaaaac ctgaaatcag atcatgcaaa
    37801 tgcatcctat acgacggact ttacactaca agagctaacg ggacaatcca agcttccgga
    37861 agataattat tttgtacttg gagataatcg aagagtttca aaagatagtc gttcgtttgg
    37921 cacgatcaat aaaactgata ttctaggtaa agcaagattt gtctattatc cacttgatga
    37981 aataaaatgg atccagtgag aaacaataaa gcgtgcagtc tgttgagact gcacgcttta
    38041 ttgtttaatc caaaatcagt ttactacctt agtacgtaaa atcaaacagc tcgtttaaac
    38101 acttttctag cctctaaagt tttgataaat gaataaacaa ccattatttg aatagggatt
    38161 tggatcatat tcctgatgaa tctacctaga aaaattactt tgaaatctgc accaaacaaa
    38221 acagacatca gccaagaatt gataaaaagg ctgactggga tcataatcaa taattgggca
    38281 gcgatgacgg aaggcaggtt tatcttttta tgatataaaa ataagccatt aataaatcca
    38341 ccaaggaaag ccgtgataag aaaagcagct tgaaacgttc ctgaaccaaa tatcgtgaaa
    38401 tttaaagtgt tcgacaacat ttcaagcaaa ccagcccaga tcggtccata tagataaccc
    38461 ataagcgcca tacttaaaaa tccgaatgtg atttgaaaat aagcaggacc aatcgctatc
    38521 ttgtataaga tgacatcaag ggctaataaa agagcagagg tcgacaacaa tcttgcattc
    38581 atttcgggca atctaaaaac gtcttttgca atcaaagtgt tcaaaatatt ctctcctttg
    38641 tcagttaata ataaaaggat accataaaat caccaatgtg tcatgacaca ttggtgattt
    38701 acatacactg gcatctaaca attaaaaaaa gggtgagaag actgctttta taaactgtaa
    38761 aaaagagatt gtacgaataa aaaaaataga ggcggagaat acttatcgta tcatccgcct
    38821 ttgttttttt gttataaaaa acgtcagatt agttatctgc ttacatcttc atccatacgg
    38881 gttctaatgt atttccgtct agatcttgga cttctaatga aaacatttct tcttcaggca
    38941 ttcccatatc tacttcgtgg aaagtaccac cattttcttt tgcaatttga gcaaattttt
    39001 ttacttcatc cgcattttca acactaaacg aaatcaaagc accacttgtt tttttattat
    39061 cagctatttc tttatctttt ataaattttt tataaaaatc atgagagaga agcattatcc
    39121 aaaaagtgtc atcccatacc attgaaccag cttcttcagt agaaaattct tcattttttt
    39181 taaaacccag cttttcataa aaagcaacgg aacgattgac atcagcaaca ggaaaattaa
    39241 caaaaaccat actattcatt tgtttcgtct cctttctgtt ttgttcgtct atcatctctt
    39301 atttaggaaa cgctgtcaaa aatttagatt catatataga aaccaaaata aaaatttgca
    39361 tcatcaaaaa agtgaagatg tgatagaatg aggactggtt cactttcact taactaatag
    39421 atggaatttc tttataacgc cgattgtaaa attaagctag acaactaaaa aagtc
//
LOCUS       DACGMI010000174        20943 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.guided.053, whole genome shotgun sequence.
ACCESSION   DACGMI010000174 DACGMI010000000
VERSION     DACGMI010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.guided.053"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(101..544)
                     /locus_tag="IXT46_003066"
     CDS             complement(101..544)
                     /locus_tag="IXT46_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAQ4948902.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINAMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(739..2079)
                     /locus_tag="IXT46_003067"
     CDS             complement(739..2079)
                     /locus_tag="IXT46_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4948903.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGIILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHAADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFAAYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLIIFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLTLRKGTLW
                     DKGISFFALAVLWLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2361..3257
                     /locus_tag="IXT46_003068"
     CDS             2361..3257
                     /locus_tag="IXT46_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAQ4948904.1"
                     /translation="MNKNDVLLIAKNKSLYFFPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAEKYKQEFTKR
                     GVTTNYFILPLRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYQFYHSENIFLLQERDLDELPEFLHTPFQPIPSELLEFFDAENWAKR
                     FFTTDSAIYEQYEYDLSSVKNK"
     gene            complement(3400..4341)
                     /locus_tag="IXT46_003069"
     CDS             complement(3400..4341)
                     /locus_tag="IXT46_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAQ4948905.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4467..5588
                     /locus_tag="IXT46_003070"
     CDS             4467..5588
                     /locus_tag="IXT46_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAQ4948906.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            5846..7348
                     /gene="lsa"
                     /locus_tag="IXT46_003071"
     CDS             5846..7348
                     /gene="lsa"
                     /locus_tag="IXT46_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lsa family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAQ4948907.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            7415..7942
                     /locus_tag="IXT46_003072"
     CDS             7415..7942
                     /locus_tag="IXT46_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4948908.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQALAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELISYE"
     gene            8154..9215
                     /locus_tag="IXT46_003073"
     CDS             8154..9215
                     /locus_tag="IXT46_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAQ4948909.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9218..10114
                     /gene="murQ"
                     /locus_tag="IXT46_003074"
     CDS             9218..10114
                     /gene="murQ"
                     /locus_tag="IXT46_003074"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAQ4948910.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            10128..12110
                     /locus_tag="IXT46_003075"
     CDS             10128..12110
                     /locus_tag="IXT46_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4948911.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12180..12626)
                     /gene="nrdI"
                     /locus_tag="IXT46_003076"
     CDS             complement(12180..12626)
                     /gene="nrdI"
                     /locus_tag="IXT46_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAQ4948912.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            12837..14261
                     /locus_tag="IXT46_003077"
     CDS             12837..14261
                     /locus_tag="IXT46_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4948913.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGFLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14438..15211)
                     /locus_tag="IXT46_003078"
     CDS             complement(14438..15211)
                     /locus_tag="IXT46_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4948914.1"
                     /translation="MTLLIKQELFKLIKKKSTAVLSVLLVALLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMESQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSIYLYLLAIIVTVLMKLILFPSISFTEKISTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIALFLALGYLVFKRKNV"
     gene            complement(15208..16113)
                     /locus_tag="IXT46_003079"
     CDS             complement(15208..16113)
                     /locus_tag="IXT46_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4948915.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSEGTIRIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVKQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDQAARTILTDAGYPLEDPDKIKLLKKNEELLGTVIQLLSAENVHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16274..16594)
                     /locus_tag="IXT46_003080"
     CDS             complement(16274..16594)
                     /locus_tag="IXT46_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAQ4948916.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGLLLISIIGIKI
                     TSGH"
     gene            17067..17753
                     /locus_tag="IXT46_003081"
     CDS             17067..17753
                     /locus_tag="IXT46_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAQ4948917.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17755..18699
                     /locus_tag="IXT46_003082"
     CDS             17755..18699
                     /locus_tag="IXT46_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAQ4948918.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            18898..19542
                     /gene="pcp"
                     /locus_tag="IXT46_003083"
     CDS             18898..19542
                     /gene="pcp"
                     /locus_tag="IXT46_003083"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAQ4948919.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            19621..20898
                     /locus_tag="IXT46_003084"
     CDS             19621..20898
                     /locus_tag="IXT46_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948920.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         6757 a         3774 c         4370 g         6042 t
ORIGIN      
        1 cacaacctct gattcacggt gttccagaag tagcttcttc ttatttcttg aagttgatca
       61 cttctggaac atcctctttt tttatttgga tggataatgg tcattccatt tctttgatca
      121 tttttttcat tttgtcgatt tcttcttctt gtgcctgaat gatttcttcc gctaattttt
      181 ttacttcagg atcttttaaa tcagctcgtt tacttgtcaa gatagcaata gagtgatgag
      241 ggatcatcgc cttcatccac gccgtatcgt tgacagttgt ttggcttcgt accataaata
      301 aggaaccggc aaaaacaaga agactagcgg ctaaaatcat agcatttatc tttttgtttt
      361 catacatttt ccacatgaac aacaacatga tgactgccat gactgcaccc atcatcaacg
      421 ccatgaatac acgtgtgcga ctgaagaaga tatgatcaag cgcataaaca ttcaaataca
      481 tcataccaaa catgactacc gtcgaaacac caatcatcaa caaaaacttc caatactttt
      541 tcatttaaaa caaactcctt tttcttcatt cctttcttct atcatgtcat gagcgtggag
      601 aacaatcaat taatctgcac agatggtttt tgaacaccgt ttattcggaa aaaagaactg
      661 caacaatttt tgtcgcagct cctttttttc aatagctcca gatattcaat ataaatagaa
      721 taaaattctc tattggtttc attcattcgt caagacgaaa gcatcattct ttttttgata
      781 actgaaataa atgaacaggt aaagcaaacc ggtcaataca gttaccccaa tggagttcgt
      841 gaataggata ccaaggaaaa tcaaccataa gactgctaat gcaaaaaagc tgattccttt
      901 gtcccataac gttcctttcc ttagtgtcag tacaaaggac gcagcactga taatgatcca
      961 gatcaataat actgtatagg aaagagaacc tgccagatag ccaaataatt tgtcaccgac
     1021 aaaataagaa agagccacac ctagataaag aacactggta caaaacagca cagcacgttg
     1081 cggtacttga tgcttgttta aaacagctag ttttctagag gaacctttcc gatctttcaa
     1141 gcggaagaac aaaattctcg aagaagcata tacacctgaa ttgatagacg agaacagagc
     1201 aagaacaatc acgaaattga cgatatctgc cgcaaatgga atattcattt tttcaaatac
     1261 catcacaaaa ggactaacgt tcgtgcctgc taaagtattc caaggaaaaa taatcaaaag
     1321 caaaaataaa ggaataatgt aaaaggaaat gattcttccc atgacgcctt tgattgcttt
     1381 aggaatcgca cgtttaggat catctgcttc gcttactgtg atagcaatca actcagaacc
     1441 gccgtaagaa tagataacta caagcaaaga actgatgatt cccttcatac cgtggggagt
     1501 aaaaccacca tgatcagtta attgttgaag ggtagggaaa acaccagtac ccaacatttg
     1561 ctgaccgaca agataagcag caaaaatgat caataggata atgacactga ttttagcaaa
     1621 ggccagccaa tattctgtct ctgcgaataa tcgtaccgaa taaagattga tgatagtagt
     1681 taaaacagcc aacataaaaa caaataccca agctgggatg tgggggaacc acaactgtaa
     1741 aaaggaagca gctgcaacag cttcagcaat gatattgata atccacatgg accagtagac
     1801 ccaatcggta aaatcggcag catgagcacc tagatatgga cgaatcaatc cagataatcc
     1861 gtggtgcgta tcaccaccac ttaaaacaat ttttcccaga cctttcatca cgatatataa
     1921 aattatgccg ccaatcaaaa aagcgatcaa tacagaaggg ccggcgattc caatcgcttc
     1981 gccacttcct ttaaatagac ctgcaccaat cgctccacct aaagctagca tggtgatatg
     2041 tcgggagcta agttgttttt tcaatttttt atcttccata aataacctct ttcttttaaa
     2101 ttcacaatca aaatgcatag taagaataaa tagtaagaat aaatagtaat aataataatg
     2161 actaatgata acaaattttc agataattac aactattcag aaaacttttg ggcatatttt
     2221 aatggaagaa tgatttattt catcgtattt tcatagaaat gttaaatttt tataaaaata
     2281 ataggaagcg ttttactggc tttttactat ttaaacaggc tatcatagga aaaagtgaca
     2341 gagaaagtga ggcggaacag atgaacaaaa acgacgtatt gctaattgcg aaaaataaat
     2401 cactttattt ttttccttcc atccgctctt tagatgtttg gtccggaaaa gatttactac
     2461 agtcggaatt cattaaatca gctcgacaac agttggcaaa ttatcagctg atcgtttttt
     2521 tagattatgg atttgatatg gagatggctc gacgcgtgcg tccatttacc aatgcaaaaa
     2581 tcgtgttatt tttttggaac cactttaaag cagaacacga ggcgatgctg aagcaggcac
     2641 aagatgaacc ggcaatcgat gagatttatc attttgattt tttagaagcg aaagaacttg
     2701 gactaaaaca taatagttcc ttttattcga aacatatgga tttttcttct agcgaaccaa
     2761 agacggatct attttttggt gcaacaaata acggcagaaa agaacgggca gaaaaatata
     2821 agcaggaatt tacaaaaaga ggtgttacga ccaattactt tattcttccg cttcgaggaa
     2881 atgaacaacc tggatacctt acttatgaag aatatctgaa aaaaaccggg gaatcgaggg
     2941 ggattctaga actgttgcgg gaagggcagc aaggagtgac tttgcgaacg tttgaatcta
     3001 tgtattttca aaagaaacta gtgacagata atcaagccat agctcattat cagttttatc
     3061 attctgaaaa tatttttttg cttcaagaac gtgatttaga tgaattaccg gaatttttgc
     3121 atacgccatt tcaaccaatc ccatcagaac tgttggaatt ttttgatgca gaaaattggg
     3181 caaaacgttt tttcactact gactccgcta tttatgaaca atatgaatac gatctttcct
     3241 ctgttaaaaa taaataaaag tgccaaccaa tcatagatga aaataaacaa gcgcaattct
     3301 tatggcaaca tgagaattgt gtttttcttt ttgaactttc atgggggtaa aaaaatgaga
     3361 accagctgct gatccagctg attctcatca gagagccttt tattctgcgc caaggattcc
     3421 ttcttttgca tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt
     3481 ttgtcctttt cgccaaacgg caccattgat gtagtcgatt tcagtcaaac gatggttttt
     3541 gatcaggtct tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga
     3601 agcaatatgt tggtacactt cttcttgatc taatgtgatt ccttcttttg ctgcgataga
     3661 agcaaactca gatacaatcg ttcgaaccat gccctctgcc gctttttgcg cacctaattc
     3721 agcaatatta caatccaata tcgtgcataa tccatttaat gttccgttta cacaagcttt
     3781 tcgccaaatg gaataacgaa cattatgact atagattgga ttcaattttg cttcttgaaa
     3841 gacttctaca actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat
     3901 ttctccatca cctaataatg tgacttttcc gggaccagct agaccagctg tccacatcgt
     3961 gatcccaaat aagatatttt tctttggtac atatttttcc agtacatctt catgacctaa
     4021 tccattcagt aaacacaaaa cataagtatt ctcagtaata atggattgga tcgaacgaaa
     4081 catatcatct aattgattcg cttttgtcaa ggctacgatc aaatccacgt gtttgttgct
     4141 ttcgatgatt tcttctggtg aatagattgg cagttttgca actacttctt tgccattaaa
     4201 gtcagcaatc aatccatttg tacgaatggc ttcaatgtga gcaggccagc gatcgatcaa
     4261 gacgacctca tttccgcttt gatgcaacat taatccgatt cggctgccca ttgctccggc
     4321 tccagctatt gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta
     4381 tatagaaaaa cagaagaaaa tagcattgtt ttgtttgaaa aaagtgaaaa aaagtgtctt
     4441 acttaagaag aaagtgaggg atatagatgg atattttggc ggcaatcgat tcatttaaag
     4501 gaagtgcttc ttcatttgaa ttaaatcagg cagttctaaa tggttgggaa gaccgtaaag
     4561 gaagaaaaat caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt
     4621 acgcgctcgg gggaacctgg cgtacgattg atgggatgga tctcttattt cgtcagcgaa
     4681 aaatcagtta tttattgacg aactggcaag gaaaaaatac cgcagtcatt gaatctgcac
     4741 aagtattagg attagattta cttgataaac caacggatca aaccatccga cttgcttcta
     4801 gttatgcctt gggagagctt atcaaagata cactgcttca agaagtggaa caaatcattg
     4861 tcactttagg aggaagcgga tgtagcgatg gtggtctagg attactccaa tctttgggtg
     4921 cttctttaga agggtacaca gaaggaaatc ctttgttatc tactagaaaa cttcatttgg
     4981 atcgaaggaa cgttcttgtt tctaaagtaa aagtgatcat cgctgcagac gtgaccaacc
     5041 catatacagg tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaacggata
     5101 cgacgttagc tttcttggat aaacaagctg aaaagattgc tcagcagata aaagatgttt
     5161 gggaggtgga tttagatgac atcccaggaa gcggagcagc aggcggtatt ggcggagccc
     5221 tttttttgtt aggagcgaag atggtctctg gttttgagtt ggtcagccaa atcactggat
     5281 tagaaaaaca gatcgaacaa gcggatgtca tcattacagg agaagggcgg attgatcagc
     5341 aaacaatcca cggaaaagtt ccatatggcg tagcagtgct tgcaaaaaaa tatcgaaaac
     5401 caataatcgc tatttgcgga agtagagacc gagagctgga aggactcttt gattttctcc
     5461 ccattgtctt aagcattcaa ttaggaccaa tcgatttaga ggaagcaatg gaacacaggc
     5521 aaacattaga aaaaacagaa atcttaggac agacactcag cagatttttc aacattctcc
     5581 cgaagtagtt gacaaaaaca atttctttat gctatcgtaa tttcaaatat aggacaaagt
     5641 gagggatccg tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct
     5701 tgtggagaca agggagcagt gtgcagattt tcgggattgg cttggttctt tcgatgtatg
     5761 ggtctttttg tgtgccccaa cccttgcatc ctctttagcc agttctgaaa ataggactgg
     5821 tcttttttta cgaggtgatg gaataatgtc taaaatcgaa ataaaaaatc tgacattcgg
     5881 ctatgacagc caaggcacat tattatttga acaagccaat ctaaactttg acacacaatg
     5941 gaaactagga cttatcggac gaaacggtcg aggaaagaca actttactga atatcctgca
     6001 aaacaaactc ccttatcaag ggcaagtgat ccatcagcaa gcgtttgtct atttcccgca
     6061 gcaaacaaaa gataaagagc gtttgaccta ttatgtgtta aatgagatta tggattttga
     6121 gatatgggaa attgaaagag agctccaact gatgcaaaca gatcctgaaa tcttatggag
     6181 agaattcagc acactatcag gaggagagaa gacaaaagtc ctactggcac tcttatttgt
     6241 ggatgacact catttcccgt taatcgatga accaacgaat catttggata tctctggcag
     6301 aaaacaagta gcggcttact tgaaaaagaa aaaacaagga ttcatcgtgg tgagtcatga
     6361 tcggggattt atcgatgaag tagtggacca tgttttagca atcgaaaaga gccaactgga
     6421 actttatcaa gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga
     6481 aatagctaaa aatgaaaaat tgaaaaaaga agtcagcagg ctaaagaaaa cagcagctga
     6541 aaaagcagaa tggtctcgtt cccgagaagg ggacaaaaca aagaaaaaag tcggattcat
     6601 cgatacggaa tctaggcgag tgaataaagg agcagtaggc gctgatgctg cacggacgat
     6661 gaaacgatct aaagcaatcg tgaatcggat ggaaacccag atcagtgaga aagaaaaatt
     6721 attaaaagat atcgagtata tcgatgcttt gacgatgaat agccaagtgt ctcatcataa
     6781 acggctgtta agcgtagaaa atcttcaatt agggtatgaa aatctgttat tcgagccagt
     6841 tcattttacg atcgaacctc atcagcggat ggcaatttca ggtcctaacg gcgcgggaaa
     6901 gtcatccatt atccattatc ttctggggac attcaacggc aaggttgtag gagaaaaatc
     6961 ccagcccaaa catttgacca ttagttacgt acgccaaaat tatgaagaca atcgagggac
     7021 attggcggaa ttcgcgaaga aaaaccgagt agactatcaa gcatttttga ataatctccg
     7081 aaagcttggg atggaaagag atgtttttca taataaaatc gaacagatga gtatgggaca
     7141 acggaaaaaa gtggaattgg ctaaatcttt atcccaacca gctgagctct atatatggga
     7201 tgaaccattg aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgattttgaa
     7261 cgtgaaacct gctatgttac tagtggaaca tgatcaaacc tttctagata aagtatctac
     7321 tgagattatt tctcttgaga aaatctaaac cttgtaatct caaagacaac aaggtatggt
     7381 taaggagaac tttgtcaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga
     7441 aacaacttgg aacgcacaag gattagtttg cgggcgagca gatgtgccgc tgactgaaaa
     7501 aggacagatg caggcacagg cactagcaga aaaggtagta gatttgcctg ttccaatcac
     7561 gaaaatcatc cattcccctc ttcaacgagc aagagataca gcacaagcag tagttgatcg
     7621 tctcaatttg ccgatgaccg ctgatgagcg attggtagaa atggattttg gggattatga
     7681 cggactgcca agcaaagatg aaaactttca aaaagcgcgt ttagcgtttg ctgtacgttt
     7741 cccaaatgga gagtcggtct tagatgtgta cgcacggatc gttcctttat tgaaagaatg
     7801 catggaagac gaagaaaatg tctacttgtt agtctgtcat aatgccttga taagagtgat
     7861 caatgcttat tttcatccaa tgcctaatga agggttcttt acattcatgg tagacaatac
     7921 agaattaatt tcttatgagt aattagactt ttgtgttatt taaataaaat gtttcaaggc
     7981 actgcttttg cttagcagtg ccttttttgt ggctgtgtca attcttttgg cattataaat
     8041 ccaattttta gaaataaaat ttaattattt taacaaaagt attgaaattt tgtttcttta
     8101 gatatatact ctagtcatag aaatgaagac ggatacagaa aaagagggat aatatgtttg
     8161 gcttttcaat atttatgaat gattctttgt cagaagagaa gaaacagtat atccgccaaa
     8221 tggcatccaa tggctttgtc ggtattttca cttccatgca tataccggaa gatgatgttt
     8281 cggcttatca aaatcgattg atcgaactag gaagcgaagc gaaaaagaat aaactagagt
     8341 tgatggtcga tatttcagga gaggcattga aacgagctgg cttttcatta gaagatctaa
     8401 cacccttgaa agcaattggt gtaacagggt taagaatgga ttatcatatt tctaatcagc
     8461 agatcgccga ctggtcacat caattgaaaa tcagtttgaa tgccagcacg atcacgccta
     8521 atgatatcga tgagttgaaa gaagcagcgg ctgatttctc acagattgaa gcttggcata
     8581 attattatcc acgtcttgaa acagggttgg acaaagaatg gtatcaggaa aaaaatcaat
     8641 ggctcaaaac tcaaggattc cttgtacaag gctttgtacc aggagataca gagttgagag
     8701 gtccactgta tcaaggatta ccaactttgg aagaacatcg agggatccat cctctggcag
     8761 gtgctcttga tctattagca agtaacacgg atattgttta tatcggagat gcaggtctgt
     8821 cagaacacgt tcaggagcaa tttgcttctt tccaaaaaga acagacagtc ttgctccata
     8881 cggaacctgt agatgaagtt ttttacgaat atatattagg aaaacatacg aatcggcaag
     8941 atgatgcaag agatgtcata cgaagcgcag atgcgcgttt tcgagagatt ccgccaatcc
     9001 cagtaagaaa tacagctaag cgtatgaaag gatctattac tttagataac gaaaagtatt
     9061 tgcgctatat gggtgagatc caattaacta aatatgattt gccagcggat gaaaaagtga
     9121 atgtagtagc caaagtcatc aaagaagaac taccgctgat caaccaaatc aaagctggta
     9181 tgaactatca atttataaga aaagaaggaa gataaaaatg agcaaaatca atttagagaa
     9241 cctaacaacg gaacgcagaa accaagaaac ttttggatta gatgaaatga gtatttctca
     9301 agcagtccaa ctcatgaaca aagaagatca gaaagtggcc gctgctgttg aaaaagaact
     9361 gccaagtatc gagccagtga tcgccaacac gattgaatcc tttaaaaaag gtggtcgctt
     9421 gatttatatg ggagctggaa cgagtggtag acttggtgta ttagatgctg ctgaatgtgt
     9481 accgacattc ggtgtagaac cggaaatggt cataggccta attgctggtg gagaagaagc
     9541 aatgactgta gccgtcgaag gagccgaaga ttcttatgaa ttagggcaag aagatctaat
     9601 caagctgaat ttaacaaaaa atgatatagt tattggtatc gcagctagcg gtcgtacacc
     9661 atatgtgatt ggtggattag attacgcaaa atcgattggt gctgttacag gaacgatttc
     9721 ttgcaataaa caagcagaaa tcagcgagca tgcggatttc ccaatcgaag tcgatgcagg
     9781 accagaattt ttgacaggct ctactcgatt gaagtcagga acagcacaaa aactgatttt
     9841 gaatatgatt tctactatca gtatgatcgg tatcggtaaa gtattcaata acttgatggt
     9901 cgacgtcaaa ccaacaaatg aaaaactaat tgaacgctca aaacgaatca tcatgcaagc
     9961 gacagaagct gactacgaaa cagctgaaaa gtactttgag gaagcagatc aaaatgtcaa
    10021 actggctatc gtcatgattt tgacaaatag tgataaagag gcagctcaag caaaattagc
    10081 tgaagcaaac ggttttgtaa aaggaacctt atgaggggga aaagaccatg gcaaaaaacg
    10141 aattgacttt ggaagaactg gcaaaacaaa tttatcaagg agcaggcggt atgggcaatg
    10201 ttgaaagcat tgtccactgc atgactcgtg tacgtatgaa ggtcatcaat gatgatcttg
    10261 taaatgtctc ggaattaaaa gcgattccag gagtacttgg cgtagtagag gatgaacagc
    10321 tccaagtcat catcggacct gggaaagtga acaaagtagc gcaggaaatg gttgacttag
    10381 caggcgtgaa attaggagaa aaacttcctt ctgctagtgc aactacagca agttcttctg
    10441 catctggaaa agaccgtgta aacgaacggg cacaagaaat gaaagcggca caaaaatcga
    10501 aacaaaaacc ctctaaaatc aaatcggtat taaaagacat ctctaatatc tttgtaccaa
    10561 tgatccctgc atttgtcggc actgggatcg tggcagggat tgccgcagtt ttagcaaact
    10621 tagtcacagc tggaacacta gacgcaggaa catggcaaca atatatcgat gtgatgaaca
    10681 tcttgaaaaa cgggatgttt agctatctag ttatctatac aggtatcaat gctgcacaag
    10741 tttttggtgc aacgccaacg cttggtggag ttatcggggc tgttgtgatg ctgacaggga
    10801 tgaatccaga agcaccactg aaaaacttgt ttaccggtga agctcttgca actggacaag
    10861 gcgggatctt aggtgttatc ttcgcagttt ggttattgtc aatcgttgag aaaaaactgc
    10921 ataaagtagt acctgatgcg gtagatatca tcgttacgcc aactctttcc ctgattgcca
    10981 tcggtctgat cgaaattttc ttcatcatgc ctttagcagg gttcatttct gacggcatgg
    11041 tcggtgggat caactgggta cttggtgttg gaggagcatt tgccggcttc gttctaggta
    11101 cattattctt gccaatggtc atgttcggac tacatcagat cttgacgcca atccatgtac
    11161 aaatgattga tgaaactggt cgtaccttat tgcttccaat ccttgcgatg gccggagcag
    11221 gacaagtggg tgcagcattg gcattatgga tccgctgcaa aaaagacaaa gaattaacag
    11281 aaatgatcaa aggggcttta ccagtcggaa tcttaggaat cggcgaacca ttgatttacg
    11341 gagtaacatt acctctagga cgtccattta ttactgcttg tatcggtgga ggtatcggtg
    11401 gggcagtgat cggaatgatc ggaaatgtcg gagcaatcgc tattggacct tcaggagccg
    11461 ctttgattcc attgatctct gatggtaaat ggttaggcta tatccttggt ttattggctg
    11521 cttacgctgg tggcttcgtt gctacattct tcttcggtat tcctaaagac cgtttagaaa
    11581 aagaagaact agcgaccgaa acagccacag taaatgaagt acctgaaaaa gcagtacctc
    11641 aagcttcagc tgaaagtgtg actatcttat catcagttgc tgacggaaca gttgtttctt
    11701 tagataaagc aagtgaccca gtttttgcac aaaaaatgat gggtgaaggt tactttgtag
    11761 aaccagaaaa cggacatatc tattccccgg ttactggagt aataagttct gttttcccaa
    11821 caaaacatgc tatcggcatt acgacaccaa atggcttaga aatcttgctt cacatgggca
    11881 tcaacacagt tgacttaggc ggtacgccat tcgatgtgaa agtaacagaa ggacagcaag
    11941 tgacacctga tacgcttgta gcagaagctg acttagaagc aatcaaagca gcagacaaag
    12001 aaacctccat gatcgtcttg gtaaccaata tggatcgtgt aaaaaacttt gtcttggaaa
    12061 aaacaggtaa agcgaaagca aaagcacctg tgatggatgt caaagcttaa taagaataga
    12121 aacaatagag aacataaaaa gaagaagccg aaatttattt ttcagcttct tcttttgtgt
    12181 tatttatttt tttctgccaa aatttgataa acgcgtgtca catcagatgg tgttccccgt
    12241 aattcataat ctgccaagaa aggaaagccg aatctttgtg cgtattgttt ggctgtcaga
    12301 caatattgat tgttgaagtt tttattaccg ctaccgacta caccaaggca aagtttatga
    12361 ttgtcttcgt attccagata ttcgcgcatc gtttcggtca agatttctgt gtcaccgttg
    12421 tctaacccat tcccgccgtc taaataagta ggaacgaaag taaaaaatgg ttctgtttct
    12481 ttcgtaaaat cactattttc atggatttct tttaaagtaa cttcaggatt gacaggatct
    12541 tctgcatgca ttttttcagc atattctgct agatgtttgg caaaagcacg cgtatttcct
    12601 gaaatcgata tatataaaat gttcatggat catcccccaa ttctttccct ttagtatagc
    12661 atctttttaa gtttttttgg tggtgtaatt tggaaaggga ctaggcgctt tgcttgtata
    12721 atgagaaaaa agtcggtaga attatatttc tattaaagtt tttattaatt aagtaaaaat
    12781 aaaaaaggtt tgttatactt tttgataaaa gcggttttac tttggaggat gcttacatgg
    12841 atacagagca acagaaaaaa ggaattggtt tgattccact tgctgcctta gtgattggtt
    12901 cagcgattgg aggtggcgta tttggtatta tgacggacat ctccggatcg gctggtggcc
    12961 cagctatctt cagctgggta ctcgtaggaa cagcaatgtt gatgctctcc ttatcgatca
    13021 ataatatcaa taaaaaacgt ccagatttaa aaggcgggat ctttagttac gcagaagaag
    13081 gttttggccg tttcgctggt tttatcagcg gttggggtta ctggctcaca tgctggttag
    13141 gaaacgtggc gttcgcaaca ttgttgatga gtgcattagg ttatttcttc cccgtattcg
    13201 aaggtggtca aaatgtggca tcgatcgtga tgagtacgat cttcttatgg ggatatgcat
    13261 ggctagtgaa tcgtggagtt gaaaatgcta gctttgtcaa tgctatcgtc acattttgta
    13321 aattagtgcc attattttta tttattgtag tagctatcag caccttttcg atccaacaat
    13381 tcattaataa cttttctagc gatatcatat tgaatgcgaa tgggcagccg atcccgtttt
    13441 ctagtcaagt attgagttgc atcatggtga tgctctgggt attcgttggt attgaaggag
    13501 cttctgtcgt aggttcacga gcaaaaaaac aatcggatgt tgggaaagca acgattctag
    13561 gaatattcgg tttgatcatt atttacgtct tggtttccat gcttccatat ggcacaatga
    13621 cgatgaatca gctgcaaacg atcaaagcgc aacctgctat gggatatgta tttgaaatga
    13681 tggttggtaa atggggggcg gtcgtgatca acggcggttt gatcatttct ttagttgggg
    13741 tttggctctc atggacaatc ttgccgattg aaacaatggg gaatatggct gaggacggac
    13801 ttttgcctaa agcatgggga aaactcaaca aaaatggggc accaacttat gctatcgtat
    13861 tgacgacgtt atgtacgaat gtctttttac tttcattatt attcactgac agtgcatata
    13921 actttgctta tacacttggt acagcagcga ttttcttcac gtggcttttc ttagggctgt
    13981 accaaatgaa gctttcttat cagcggaaag agtgggtcca atttttagta gggtttttag
    14041 caagtgcttt tcaagtatgg gccatgctag ttgtagcctt taatgaagtg atgcttgttc
    14101 ttgttctttt cttaccaggt atttattttt acctcaaagc acgtaaagaa caaaacgaac
    14161 ctgtacaaca tatccactta gataagattt tacttatcgg tgtgacgatg gtcggagtaa
    14221 tcgcaatggt tttatttgcc actgggatgc ttcacgtata gaagtataaa gagaggctgt
    14281 gaagcctgtg gtttattcaa aaaagaagcg gtgacaacat tcgtgtcatc gcttcttttt
    14341 ttgaataaat ggtgttcaag aagtagcttc ttctaaaaat aagccgaaat ttcttgaaac
    14401 tggccacttc tgtcacaact tctttgttaa tgaaccatca tacatttttt cgcttgaata
    14461 cgaggtatcc caatgctaag aacaaagcaa tgtaagctaa attgccaaac agcatttgat
    14521 tagtagaaag atgagtcaat tgcttcataa tctcttcgtt gccaatttgg ttttgcagat
    14581 tcagcatact gattggattc catttgatcc actcccattt ttgaatgagt gcgatgagga
    14641 taccagatat gattgatgaa gcaaaataaa agacgatccc tgctgagatg gaggcaccgg
    14701 aactattgat aaaacaagca atcatcaaca ctaaacttaa aattagccat aaaccgatat
    14761 aactacccaa agtataagtg aataagcttt ggatcagtgt ctgaccagta gaaatcttct
    14821 ccgtaaagga aatcgaaggg aaaaggatca gtttcatcag cacggtgaca ataatagcta
    14881 aaaggtataa ataaatagaa taaataacta atgtgatcca tttacttact aatatttctc
    14941 ctcgagaata ctttcgataa aggagatttt tcaatgtacc atattgtgat tccattgaaa
    15001 tgatcgtact tgcagcagca atcatgataa agacaatcca agatgtggca ctgaaaagct
    15061 gagcagtcat ttcaactgga tcaatgatcg tcgtgtattt tttggctaga agtgctgttc
    15121 ctatgagcaa agcaactaat agaacagata aaacagcagt tgactttttc ttgatcaatt
    15181 taaataattc ttgttttata agcaacgtca tttttcttct tcccccttta ctgaatccag
    15241 aatttccaat agggaagatt ccaaatcatt cgtcagatgc tggacatctg tcacatggac
    15301 attttctgca gacaataact ggataacagt tcctaataac tcttcgtttt tttttagaag
    15361 cttgatttta tcaggatctt ccaagggata tccagcgtct gtcaagatcg ttcgagcagc
    15421 ttgatcattt gtcgtagaga taacgatgaa atcttgcgct gtttggttca attcagccat
    15481 tgtacattgt ttgatgattt ttccttgatt gatcaggatc agctcatcga ccattttttc
    15541 aagctcgctg agtaagtgac tggagatcaa gaaagaggtg ccctgagtag ccaagtcggt
    15601 aatgattttt cgcacatctc ttgttgcttg tggatccaaa ccgttcatcg gctcatctaa
    15661 aataacgata gacggatggt tcagtaaggc aagagcaatt cccaattttt gtttcattcc
    15721 cagcgagtag gatttcgctt ttttgtgaat gtatttttcc atcttgagct gtttcacgat
    15781 agtgtcgata gcagatacat cgtttgtttc agagaataac ttcagatgat cataacctgt
    15841 taagaatgga tagatacccg gatattcgat caatgctcct acttgttcta atcctttatg
    15901 actagaggga gaaatctcat tttcaccaat acggatcgtt ccttctgagt aatggatcag
    15961 tcctaaaata gctttcatga tcgttgtttt tccagcgcca ttaggaccta ctaatccaac
    16021 gattttgcca ggagataagc taaaactgac atcgctgagg gcttgtttgt gaccaaagtt
    16081 cttggataat tcttggaccg aaagactttt caaaaatatt cactcctttt ctatagatag
    16141 tacaagcata cacctgatga gtagagaagt cgctaggtca ttagtcttat tttcttgttt
    16201 tttcatagaa agaggaatat caaataaaaa gccccgcttt ttctgatcag tccttgtctg
    16261 cttgtctaag tatctagtga ccgctagtga ttttgatgcc aatgatgctg atgagcagca
    16321 acccgacaaa gaaccaagtg gaaagattca gcttatcatg aaacaagacc acaccaataa
    16381 tgaccgaacc aactgcgcca atccctgtcc aaataggata agagagactc ataggcaaac
    16441 ttttgattgc ctttgacaaa aagtaaaaac tagcaatcat tccaatcact gtgtaaaaag
    16501 aataattgat tttagaaaaa ccatcactcc atttcatcat cgttgaccag aatacttcca
    16561 aaattcctgc tatgattaat tccatccatg ccatacatac gttcctcctt caatataaaa
    16621 aatacacaaa aagaggagaa tcatcccttc aaagacctaa tggaatgatc atcctctttt
    16681 ttactacccg gtggcagatc gtatatcttt ttctgtagta tagcacacct atccagatat
    16741 cggcaatctc atacttttta gtaaagtgta acaagcattg acggatatat cgttagcaga
    16801 aaagaagatg aatgctttgc aatttcatag aaaggagttg ttatttatta atcatttaaa
    16861 aaaacagtaa ctagacctta tttttatata ttagcaggca ataaattaaa aaaagcttta
    16921 tcttacaata agtaaggtga attatataat aaaaaaataa cgaaaaatat ttaaaaatag
    16981 tgtctatttc gtgagaaaac aactatattt tttatgtgtt ttgctttata attaaaaaaa
    17041 tattgtcatt ttatggagga aaatatatgg aaaattatct tagcctttta ggcgtcttga
    17101 ttgttattct cgggtttgca tttaaattag actcgatatt gatcgtaatg gttgctttag
    17161 ttgttacagc tttgactggc ggtcttggca ttcaaggaat gttagaactt ttaggtacaa
    17221 gttttgtaaa caatcgcggg atggcgattt ttatcatcat tatgttggca acaggaacgc
    17281 ttgaaagaaa tggtctgaaa gaatcagcgg cttccttgat caagcgattc aagaaagtat
    17341 ctgctggtat gattgtagat atttatggga tctttcgaat gatctttgcg gcttttaacg
    17401 tgagttttgg tggagttgct ggatttgttc gtccaatcat tttaccgatg gcattgggga
    17461 ccatcgaatc aaaagggtta gaagtccatc ctaagcatga agaagaacta aaaggtatgg
    17521 cttcagctat ggaaaatgtc tgctggttct ttggccaagt actattcatc ggaggagcag
    17581 gggcgttgct agtccaatca acactgaaag atctaggata tgacgtaaca ttgggacagc
    17641 ttgctttagt ggaagttcca gtggctatca cggctttagt tgtggcaagt gtctacttct
    17701 atcttaaaga aaagaaatta gcgaagaaat attatccagg aaaggggcaa taagatggac
    17761 ttttttacaa atcctgatat tttattaggc gataaattac tggagatcct ttatatcgtg
    17821 atgggactcg tattgattta cactggagta agaaatttaa cagataaaac caatcctcat
    17881 cgttatgggt cagccttttt ctggacggtc ttaggggtag ttattgcagg aggaagatgg
    17941 cttccggcaa tcgtgaacgg tggcttgatc tttgcgatga ccataccagc aattgctaag
    18001 aaagtcagca aaggagaaag ccggcttcca tcaaaagaat atatggaaaa aatgtcagac
    18061 aaactaggaa tgaaaatttt tattccagct ttgagtatcg gtgtctttgc gatcttgttt
    18121 gctctattta ccaatttagg tgctttagtc ggcgtgggcg tcggtgtttt tgcagccatg
    18181 ctaatcttga tgttcttttc tcgagataat cgaccaagta catttttaga tgatgcagca
    18241 gatatgctgg gcacagtagg gccgttaagc atgttgccaa tgcttttagc ttctctaggt
    18301 gcggtattta caagcgctgg agttgggaca gtgatttcca atgcagtagg tacgatcgtt
    18361 ccagaaggaa atgtgaacat cggcatcatc atttacgctc ttggcatggt gatatttacg
    18421 gtaatcatgg ggaatgcatt tgcggccatc accgtgatga cggttgggat cggtgcacca
    18481 ttcgtattta gtcatggagc gaatccagcg ttaataggaa tggttgcatt gacttgcggt
    18541 ttttgtggga ccctgctgac accgatggct gctaacttca atatcgtgcc tgtagcgatg
    18601 ctggagatga aagacaaata cggagtgatc aaaaaccagt tgtttattgc gttatttatg
    18661 ctagttttcc aaattgctta tatgattcta tttaaataat agaagagagg ggttgtgaca
    18721 gaataattgt cgcaacctct tctaacattg tagtggaaca ctattttttt ataagaatat
    18781 attaagtttg atctgttatg ttatttaaac tattgtttcc tttatttacg ctgttcaagg
    18841 aaaatggtat gataaaagat aaccatatgt taaatcaatc ggacggagga acaacagatg
    18901 aaagtactag taacaggttt tgatccattt ggtggggaca aagtgaatcc agcctatgaa
    18961 gcagtaaaaa aaatgccaga tgaaatcagc ggtgctgaaa tcatcaaagt ggaagtaccg
    19021 accgtattcg aaaaaagcag tcaagtagtc aaagaagcca tccaacagca ccaaccagat
    19081 gtcgtgatct gtgtcggaca agcaggtggg cggtcagcag tctcgttcga acgtgtcgca
    19141 atcaatctag cagaagcaag aatccctgat aatgaaggaa atcagccatt cgatacggct
    19201 ttagaagaaa acggtccagc cgcttacttt acctcattgc caatcaaagc aatgacaaaa
    19261 aatgtacaag atcatggtct accagcgtac atctcttata cagcaggaac atttgtctgc
    19321 aatgatatca tgtatcgttt gcttcatttg atcgaaacac aattcccggc aattcgaggt
    19381 gggttcatcc acgtgccatt ctcacccgat caagtgatcg atcgtccagt gggtacgcct
    19441 tctatgtctt tagaagacat tgcttcttct ttgacttatg cagttgaagc agcagtagaa
    19501 aataaagaag atatttccgg aaatgccgga acaactcact aatttagcaa gaaacactgg
    19561 ctggttgcta acgttatgtt agtagccagc tttttgtaat tagaaaggaa agaaacagcc
    19621 gtggaagaat ggcaatccgt ctttgaagaa tggtttccaa aagaaatcag caaaagctat
    19681 cccatcaaaa tttctaaaca atacacaagc agtcaacgtt gggagatcta tgcaaaatta
    19741 acgaaaaaac agcgggaact agtcgataag caccgccgat atctaatcag ctctcgtttt
    19801 atggaagaac attatttagc tgcaacagat tgggtgtttt ctgacttcaa gatcaatccg
    19861 ttttttcgaa caaaacgaag ccagcaaaaa ttgtattgtg agtgtggtag agaattaaaa
    19921 gtgcaataca tcgttaaatc gccaaaaacc ggaaagatcc taaaactagg catcaaccac
    19981 tttgccgatc acctgcatgt ctctccgaca gtggcagctt cgatccatca gggaatgaca
    20041 aaagttgatc tggccttaga cgaattatta tggcttaagc agaagaatat cgattttcct
    20101 gaaggactat ggcaaaaata ctgttttgtc ttgtaccaaa atcgtcggat gaaacagcca
    20161 tatttaccgg atataaaatt agctcagcgg ctcgcagaat ttcgccaagt agaaatgccg
    20221 atttacatag cggattatca agcattggaa aatgaaatca agaaaataag tgaacacatc
    20281 aatgggcagt caaaaaagcg acagataaaa aaagaactat ttgacgactt tgcagaagaa
    20341 ttagtaaagg atgtagaaga attcttgatc aactatcgcg catttttacg taaagattgg
    20401 caatccatcg tatatgaaga agtgccagta catcctaatg cttattttga aacatttatt
    20461 tccgtgttga gaaagacaaa acgtcaacga acaccagaag tcactgctca gatggaatat
    20521 tttgcgaaaa accaacgatt catccaacca aaaatctatc tatttatttg gaagcaatat
    20581 tgtcgctatg gttttacaga agggttcttc gacagcattc ctcggatagt cagaaatggt
    20641 tttttaaaag tattgcgtaa agaacgagaa gctatacaat ctgctgataa gaaagaccgt
    20701 acagtctcaa aagaaaaatg gcaactagta gtgaaagata tccaatctgg aaatgtgcaa
    20761 gagacaatcg acaaatggaa aggaaaacat tatcgtttta ctgaagctca gaaacaagcg
    20821 ttggaatatt atcagaagtt agaagaatca ctgcgtttca atgatgaggc aagaaagtat
    20881 ctgaaggaat tactataaaa aatagaggct gggacagaag cgtttaactc caagaaataa
    20941 gaa
//
LOCUS       DACGMI010000175        13213 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.guided.080, whole genome shotgun sequence.
ACCESSION   DACGMI010000175 DACGMI010000000
VERSION     DACGMI010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.guided.080"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(204..2162)
                     /locus_tag="IXT46_003085"
     CDS             complement(204..2162)
                     /locus_tag="IXT46_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4948921.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="IXT46_003086"
     CDS             complement(2159..3031)
                     /locus_tag="IXT46_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4948922.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="IXT46_003087"
     CDS             complement(3373..4245)
                     /locus_tag="IXT46_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4948923.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="IXT46_003088"
     CDS             4373..4942
                     /locus_tag="IXT46_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAQ4948924.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="IXT46_003089"
     CDS             5009..5746
                     /locus_tag="IXT46_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4948925.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="IXT46_003090"
     CDS             5977..7245
                     /locus_tag="IXT46_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAQ4948926.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="IXT46_003091"
     CDS             7732..8196
                     /locus_tag="IXT46_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4948927.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="IXT46_003092"
     CDS             8180..8809
                     /locus_tag="IXT46_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAQ4948928.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            9163..10641
                     /gene="msr"
                     /locus_tag="IXT46_003093"
     CDS             9163..10641
                     /gene="msr"
                     /locus_tag="IXT46_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAQ4948929.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="IXT46_003094"
     CDS             10688..11134
                     /locus_tag="IXT46_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAQ4948930.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="IXT46_003095"
     CDS             complement(11333..11848)
                     /locus_tag="IXT46_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4948931.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="IXT46_003096"
     CDS             11965..13167
                     /locus_tag="IXT46_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4948932.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4114 a         2427 c         2708 g         3964 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattttct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg caaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactacg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac cggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DACGMI010000176         7959 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.guided.098, whole genome shotgun sequence.
ACCESSION   DACGMI010000176 DACGMI010000000
VERSION     DACGMI010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.guided.098"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            128..1564
                     /locus_tag="IXT46_003097"
     CDS             128..1564
                     /locus_tag="IXT46_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4948933.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="IXT46_003098"
     CDS             1753..4200
                     /locus_tag="IXT46_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAQ4948934.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="IXT46_003099"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="IXT46_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAQ4948935.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="IXT46_003100"
     CDS             complement(5690..6793)
                     /locus_tag="IXT46_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4948936.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="IXT46_003101"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="IXT46_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAQ4948937.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2666 a         1359 c         1729 g         2205 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgcaggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattactt
//
LOCUS       DACGMI010000177         6706 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.guided.106, whole genome shotgun sequence.
ACCESSION   DACGMI010000177 DACGMI010000000
VERSION     DACGMI010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.guided.106"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            111..194
                     /locus_tag="IXT46_003102"
     CDS             111..194
                     /locus_tag="IXT46_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAQ4948938.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="IXT46_003103"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="IXT46_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAQ4948939.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1226..1486
                     /locus_tag="IXT46_003104"
                     /pseudo
     CDS             1226..1486
                     /locus_tag="IXT46_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
     gene            1649..2314
                     /locus_tag="IXT46_003105"
                     /pseudo
     CDS             1649..2314
                     /locus_tag="IXT46_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284571.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2350..2595
                     /locus_tag="IXT46_003106"
     CDS             2350..2595
                     /locus_tag="IXT46_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAQ4948940.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2698..3567
                     /locus_tag="IXT46_003107"
     CDS             2698..3567
                     /locus_tag="IXT46_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAQ4948941.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3548..4282
                     /locus_tag="IXT46_003108"
     CDS             3548..4282
                     /locus_tag="IXT46_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4948942.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4315..5223
                     /locus_tag="IXT46_003109"
     CDS             4315..5223
                     /locus_tag="IXT46_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAQ4948943.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5220..5762
                     /gene="sat4"
                     /locus_tag="IXT46_003110"
     CDS             5220..5762
                     /gene="sat4"
                     /locus_tag="IXT46_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAQ4948944.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5855..6649
                     /locus_tag="IXT46_003111"
                     /note="aph(3')-IIIa"
     CDS             5855..6649
                     /locus_tag="IXT46_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAQ4948945.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2350 a         1009 c         1400 g         1947 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca ttttgtgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttcta tatttattta cagatgtaat
      301 aacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 attcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggagtat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct tttttaaatt
     1081 tggaaagtta cacgttacta aagggaatgg agataaatta ttagatatac tactgacagc
     1141 ttccaagaag ctaaagaggt ccctagcgcc tacggggaat ttgtatcgat aaggggtaca
     1201 aattcccact aagcgctcgg gaccccttgt aggaaaatgt cctaagtgtg gcaacaatat
     1261 tgtattaaaa aaatcgtttt atggttgttc aaattatcct gaatgtaagt ttactttagc
     1321 tgaacatttt agaaagaaaa aactaaccaa aacgaatgta aaagaattac tggagggaaa
     1381 agaaaccctg gtaaaaggaa tcaaaaacaa agagaaaaag ccctacaatg ccgttgtaaa
     1441 aattggggaa aagggatata ttgattttat ctctttttca aaataaacat ggggctgacc
     1501 caaaagtagc tcctatatga aaaatagagg tctttccatt tagatagtag tggaaagacc
     1561 tctatttatc ttttgaaagt gaatacaaaa ataaagcaca ctctgctata atataggtga
     1621 ttaatccatt tgagagaggt gctttatcat gtatcaaaat tataccataa accaactttg
     1681 tttgcctata gatcttgaaa ttaaattaga agaaaatgat tttgctcatg ccattgtgca
     1741 gtttgttgac tctattcccg atgaagtctt tcttccttat tatcaatcta tgggtagacc
     1801 ccaatatcat cctcgtatgc tactttccat tattctttgt gcctatattc aaggggttta
     1861 ttcgggccgc caaatacaaa atatgctgat agatagtatt cggatgcgct acttatctca
     1921 agagcaattc cctaactttc gtactattaa tcgttttcgc gttcatccga ttatgaacga
     1981 tattctagat cattcatttg ttcaatttcg tgagctactg gttcaaagtg gcttaatcag
     2041 tggcagtgct ctatacattg atggtacaaa aattgaagcg gatgcgaata aatactcttt
     2101 cgtttggaaa aaaagtattt taaagtataa ggatagcctt gatcaaaaag cccttgaaaa
     2161 ctaccaacaa atggtggaaa caaaaatctt acctgagtta atagatgatt taaaggatga
     2221 actttctata gaagagattg aaaggattcg tcaatctttg gaagaaaagg aaaatcaatt
     2281 aattgaagcg attgaccaaa ccgaaacagt agaagggggc tgacccatta ttaataagga
     2341 gtggacaaca tgattgatgt aaatgagcta ttggaagaag ctattagaga aactgaaaat
     2401 ctaaatgatg gcgaagtttt tcttgttaaa gatttattca agggatatgt ggggaatagg
     2461 atacccagaa aggatcgact tctgcttgga acgttatttt taaaccatgt tagcaaaatg
     2521 aatggtaatt taaaggctat tgaaaagact tcatctaatc agcagaggta taaaaagaca
     2581 attgataagt tttaactatc ttttgtgaaa ttaaaaaaat tataaatatg ttgagtagaa
     2641 gcaaaagatt tggcttggaa tttttacagc agtgaatcga taaaaggagc atgcttgatg
     2701 gtagataata ttattaaatc agtagcagag aaattatcct ctctgtctta tatagaaggt
     2761 attgttttag gtggttcacg tgcaaggggc acccatacag aggattcgga tatagatatc
     2821 ggcatctatt acaattcaga atcatttgac ataaatacta ttaatcaatt cgctacaaag
     2881 ctggatgatg agcatagaaa taaccttgtt gtacctcccg gagcatgggg tgattggatt
     2941 aatggcggcg gatggttagt cataaacggg tatcatgtgg atttaatttt acgtgatatt
     3001 aaacgtgtgg aacaaataat gaaagataca gagcacggaa ttgttactgc caattatcag
     3061 actgggcatc cccatggtta tattagtgca atgtatcgag gagaattagc gattagcaaa
     3121 atactatatg ctaagaatga aagcttatgc gaattaaaaa aacaggcaga aacttatccc
     3181 aatgctttgc agaaaagttt agttaacttt tttatgtttg aagcagggtt ctctttaatg
     3241 tttgtaaaag caaattcggg aacagacgat aaatattata ttgcgggtca tgtttttcgt
     3301 atagtttcat gtttaaatca agtgttattt gcatgtaata atgcttattg tatcaacgaa
     3361 aagaaagcta taaaactgct tgaaactttt gaacataaac ctgaaaaata taccgagaag
     3421 gtaaatcata tttttgaagt actcggtatc tcactttttg aatgctacga catgaccgag
     3481 aagctttata atgaagtgaa tgaaattgta tcggagataa ataacttttt aaacgaggag
     3541 agttcagatg aaagaaaaca aatatgatga taatatattt tttcaaaaat acagtcaaat
     3601 gagtcgctcg cagaaaggac tggctggtgc gggagaatgg gagactttga aaaagatgct
     3661 acctgatttt aagggtaagc gtgtgcttga tttaggatgc ggctatggat ggcactgtat
     3721 atatgcgatg gaaaacggtg cttcctctgt agtaggtgtt gatatttctc ataaaatgct
     3781 cgaagtagca aaaggaaaaa cccattttcc acagattgaa tatgaatgct gtgccataga
     3841 agatgtggat ttcccagagg agagctttga tgtaatacta agttcgcttg cgtttcatta
     3901 tgtagcagac tatgagaatt taataaaaaa gatatatagg atgctgaagg ctggtggcaa
     3961 tttagttttt acagttgaac atcctgtttt tactgctcat ggaacacaag actggtatta
     4021 taacgaaaaa ggagaaatac tgcatttccc ggtggacaat tattattatg agggcaaacg
     4081 gacagctatg tttttggaag aaaaggttac aaaatatcat agaacactga ccacatatct
     4141 aaatacactg ctttcaaata gttttataat aaatcagatt gtggagccac agccgccaga
     4201 gaacatgatg gatattccgg ggatggcgga tgaaatgcga cgcccaatga tgctgattgt
     4261 atcggcaaaa aagaagatgt aataatatag aaaaaataaa cgaggagtat gtaaatgaga
     4321 tcagaaaaag aaatgatgga tttagtactt tctttagcag aacaggatga acgtattcga
     4381 attgtgaccc ttgaggggtc acgcgcaaat attaatatac ctaaagatga atttcaggat
     4441 tatgatatta catattttgt aagtgatata gaaccgttta tatctaatga tgactggctt
     4501 aatcaatttg ggaatataat aatgatgcaa aagccggagg atatggaatt attcccacct
     4561 gaagaaaagg gattttccta tcttatgcta tttgatgatt acaataaaat tgatcttacc
     4621 ttattgccct tggaagagtt agataattac ctaaagggcg ataaattaat aaaggttcta
     4681 attgataaag attgtagaat taaaagggac atagttccga ctgatataga ttatcatgta
     4741 agaaagccaa gcgcaaggga gtatgatgat tgctgcaatg aattttggaa tgtaacacct
     4801 tatgttatta aaggattgtg ccgtaaggaa attttatttg ctattgatca ttttaatcag
     4861 attgttcgcc atgagctgct gagaatgata tcatggaagg tcggcatcga aacaggcttt
     4921 aaattaagtg taggcaagaa ctataagttt attgaaaggt atatatccga ggatttgtgg
     4981 gagaaacttt tgtccaccta ccggatggat tcctatgaaa acatatggga agcattattt
     5041 ctatgccatc aattgttcag ggcggtatcc ggtgaggtgg cggaaaggct tcattatgcc
     5101 tatccggagt atgataggaa tataacaaaa tataccaggg acatgtataa aaaatacact
     5161 ggtaaaaccg gctgcctgga tagcacatat gccgctgata tagaagagag gcgggaacag
     5221 tgattacaga aatgaaagca gggcacctga aagatatcga taaacccagc gaaccatttg
     5281 aggtgatagg taagattata ccgaggtatg aaaacgagaa ttggaccttt acagaattac
     5341 tctatgaagc gccatattta aaaagctacc aagacgaaga ggatgaagag gatgaggagg
     5401 cagattgcct tgaatatatt gacaatactg ataagataat atatctttac taccaagacg
     5461 ataaatgcgt cggaaaagtt aaactgcgaa aaaattggaa ccggtacgct tatatagaag
     5521 atatcgccgt atgtaaggat ttcagggggc aaggcatagg cagcgcgctt atcaatatat
     5581 ctatagaatg ggcaaagcat aaaaacttgc atggactaat gcttgaaacc caggacaata
     5641 accttatagc ttgtaaattc tatcataatt gtggtttcaa aatcggctcc gtcgatacta
     5701 tgttatacgc caactttgaa aacaactttg aaaaagctgt tttctggtat ttaaggtttt
     5761 agaatgcaag gaacagtgaa ttggagttcg tcttgttata attagcttct tggggtatct
     5821 ttaaatactg tagaaaagag gaaggaaata ataaatggct aaaatgagaa tatcaccgga
     5881 attgaaaaaa ctgatcgaaa aataccgctg cgtaaaagat acggaaggaa tgtctcctgc
     5941 taaggtatat aagctggtgg gagaaaatga aaacctatat ttaaaaatga cggacagccg
     6001 gtataaaggg accacctatg atgtggaacg ggaaaaggac atgatgctat ggctggaagg
     6061 aaagctgcct gttccaaagg tcctgcactt tgaacggcat gatggctgga gcaatctgct
     6121 catgagtgag gccgatggcg tcctttgctc ggaagagtat gaagatgaac aaagccctga
     6181 aaagattatc gagctgtatg cggagtgcat caggctcttt cactccatcg acatatcgga
     6241 ttgtccctat acgaatagct tagacagccg cttagccgaa ttggattact tactgaataa
     6301 cgatctggcc gatgtggatt gcgaaaactg ggaagaagac actccattta aagatccgcg
     6361 cgagctgtat gattttttaa agacggaaaa gcccgaagag gaacttgtct tttcccacgg
     6421 cgacctggga gacagcaaca tctttgtgaa agatggcaaa gtaagtggct ttattgatct
     6481 tgggagaagc ggcagggcgg acaagtggta tgacattgcc ttctgcgtcc ggtcgatcag
     6541 ggaggatatc ggggaagaac agtatgtcga gctatttttt gacttactgg ggatcaagcc
     6601 tgattgggag aaaataaaat attatatttt actggatgaa ttgttttagt acctagattt
     6661 agatgtcggt tctgttgcaa agttttaaat ctactatcaa ataagg
//
LOCUS       DACGMI010000178         5775 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.guided.113, whole genome shotgun sequence.
ACCESSION   DACGMI010000178 DACGMI010000000
VERSION     DACGMI010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5775
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.guided.113"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(85..3009)
                     /locus_tag="IXT46_003112"
     CDS             complement(85..3009)
                     /locus_tag="IXT46_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HAQ4948946.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SE"
     gene            3155..3730
                     /locus_tag="IXT46_003113"
     CDS             3155..3730
                     /locus_tag="IXT46_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016204422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4948947.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3944..4639
                     /gene="vanR"
                     /locus_tag="IXT46_003114"
     CDS             3944..4639
                     /gene="vanR"
                     /locus_tag="IXT46_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAQ4948948.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4617..5768
                     /locus_tag="IXT46_003115"
     CDS             4617..5768
                     /locus_tag="IXT46_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4948949.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPGFCCKVLNKE"
BASE COUNT         1782 a         1090 c         1089 g         1814 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccgtc taaaatactt tgttttttta
       61 cctgtctact tgacaggggg cagttcactc tgagttaaaa tggtattctc ctagtaaatt
      121 aatatgttcc caacctaagg gcgacatatg gtgtaacaaa tcttcattaa agctacctgt
      181 ccgtttttta tattcaactg ctgttgttag gtggagagta ttccaaatac ttatagcatt
      241 gataattatg tttaaagcac tggctctttg caattgatgc tgtatggtgc gttctctaag
      301 ctcaccttgt tttccgaaga aaatagctct tgccaatcca ttcatggctt ctcctttatt
      361 caatcctctt tgtatttttc ttcttaatga ttcatccgat atataattca aaataaagat
      421 cgttttttct attcggccca tctcacgtaa ggctgtagct aagctgtttt gtcttgaata
      481 ggaacctagc ttccccataa taagggatgc tgaaactgtt ccctccctta tagaatgagc
      541 taatcgcaaa acatcctcat aattttcttt aatgaccttt gtatttattt gtccacgtaa
      601 aatggcttct agttttggat actcacttgc tttatctatc gtaaataatt ttgagtccga
      661 taaatccctt attcttgggg caaatttaaa tcctaataaa tgagtcagtc cgaatatttg
      721 gtcagtgtaa ccggcagtgt ctgtataatg ttcctctatg tttagatccg tctcatgatg
      781 taacaaacca tccaaaacat gaatcgcatc tcttgaatta gtatgaataa tctttgtgta
      841 gtaagaagag aattgatcac ttgtaaatcg gtagatggtg gctccttttc cagttccata
      901 atgtggattt gcatctgcat gtagtgatga aacacctagc tgcattctca taccatctga
      961 cgaagatgtt gtaccgtcgc cccaatagaa aggcaattgt aatttatgat gaaagtttac
     1021 taatatggct tgggctttat tcatggcatc ttcatacatg cgccattgag atacattggc
     1081 tagttgctta tatgtaagtc cgggtgtggc ttcggccatc ttgctcaagc caatattcat
     1141 tcccattcct aaaagggcag ccatgataat gattgtttct tccttatctg gttttcgatt
     1201 attggaagca tgagtgaatt gctcatgaaa tcctgttata tgggccacat ccatgagtaa
     1261 atcagttaat tttattcttg gtagcatctg ataaaggctt gcactaaatt tttttgcttc
     1321 ttctggaaca tctttttcta agcgtgcaag tgatagcttt cctttttcaa gagaaacccc
     1381 atctaactta ttggaattgg cagctaacca ctttaacctt tcattaaagc tgctggttct
     1441 ctccgttata taatcttcga atgataaact aactgataat ctcgtattcc ccttcgattg
     1501 attccatgta tcttccgaaa acaaatattc ctcaaaatcc ctatattgtc tgctgccaac
     1561 aatggaaaca tctcctgccc gaacatgctc ccgaagttct gttaaaacag ccatttcata
     1621 gtaatgacga ttaattgttg taccatcatc ctcgtataaa tgtcttttcc atcgttttga
     1681 aataaaatcc acaggtgagt catcaggcac ttttcgcttt ccagattcgt tcattcctcg
     1741 gataatctca acagcttgta aaagtggctc atttgccttt gtagaatgaa attccaatac
     1801 tcttaatagc gttggcgtat attttcttag tgaataaaac cgtttttgca gtaagtctaa
     1861 ataatcatag tcggcaggac gtgcaagttc ctgagcctct tctactgaag agacaaaggt
     1921 attccattca ataaccgatt ctaaaacctt aaaaacgtct aatttttcct ctcttgcttt
     1981 aattaatgct tgtccgatgt tcgtaaagtg tataactttc tcatttagct ttttaccgtt
     2041 ttgtttctgg atttcctctt gagccttacg accttttgat aacaaactaa gtatttgcct
     2101 atcatgaatt tcaaacgctt tatccgttag ctcctgagta agttgtaata aatagatggt
     2161 taatatcgaa taacgtttat tttcttgaaa gtcacggaat gcatacggct cgtatcttga
     2221 gcctaagcga gacagctgca acaggcggtt acggtgcaaa tgactaattt gcactgtttc
     2281 taaatccatt cctcgtatgt attcgagtcg ttctattatt tttagaaaag tttcgggtga
     2341 aggatgaccc ggtggctctt ttaaccaacc caatatcgtt ttattggatt cggatggatg
     2401 ctgcgaggta ataatccctt caagcttttc tttttgctca tttgttagag atttactaac
     2461 cgtattaaat agcttctttt cagccattgc ccttgcttcc cacaccattc tttcaagtgt
     2521 agtgatagca ggcagtataa ttttgttttt tcttagaaaa tctatgcatt catgcagtag
     2581 atgaatggca tcaccatttt ccaaagctaa ttgatgaagg tacttaaatg tcattcgata
     2641 ttcactcagg gtaaaagtta caaagtcgta ttcacttcga atttctttca aatgatccca
     2701 aagtgtattt tccctttgag gataatgatc aagcgaggat ggactaacac caatctgttt
     2761 cgatatatat tgtatgaccg aatctgggat gcttttgata tgagtgtatg gccaaccggg
     2821 ataccgaaga acagctaatt gaacagcaaa tcctaaacgg ttttcttccc tccttcgctt
     2881 attaactatt tctaaatccc gtttggaaaa agtgaagtag gtccccagta tccattcatc
     2941 ttcagggatt tgcataaaag cctgtctctg ttccggtgta agcaattctc tacctctcgc
     3001 aattttcatt cagtatcatt ccatttctgt attttcaatt tattagttca attatatatc
     3061 aatagagtgt actctattga tacaaatgta gtagactgat aaaatcatag ttaagagcgt
     3121 ctcataagac ttgtctcaaa aatgaggtga tattttgcgg aaaatcggtt atattcgtgt
     3181 cagttcgact aaccagaatc cttcaagaca atttcagcag ttgaacgaga tcggaatgga
     3241 tattatatat gaagagaaag tttcaggagc aacaaaggat cgcgagcaac ttcaaaaagt
     3301 gttagacgat ttacaggaag atgacatcat ttatgttaca gacttaactc gaatcactcg
     3361 tagtacacaa gatctatttg aattaatcga taacatacga gataaaaagg caagtttaaa
     3421 atcactaaaa gatacatggc ttgatttatc agaagataat ccatacagcc aattcttaat
     3481 tactgtaatg gctggtgtta accaattaga gcgagatctt attcggatga gacaacgtga
     3541 agggattgaa ttggctaaga aagaaggaaa gtttaaaggt cgattaaaga agtatcataa
     3601 aaatcacgca ggaatgaatt atgcggtaaa gctatataaa gaaggaaata tgactgtaaa
     3661 tcaaatttgt gaaattacta atgtatctag ggcttcatta tacaggaaat tatcagaagt
     3721 gaataattag ccattctgta ttccgctaat gggcaatatt tttaaagaag aaaaggaaac
     3781 tataaaatat taacagcctc ctagcgatgc cgaaaagccc tttgataaaa aaagaatcat
     3841 catcttaaga aattcttagt catttattat gtaaatgctt ataaattcgg ccctataatc
     3901 tgataaatta ttaagggcaa acttatgtga aagggtgata actatgagcg ataaaatact
     3961 tattgtggat gatgaacatg aaattgccga tttggttgaa ttatacttaa aaaacgagaa
     4021 ttatacggtt ttcaaatact ataccgccaa agaagcattg gaatgtatag acaagtctga
     4081 gattgacctt gccatattgg acatcatgct tcccggcaca agcggcctta ctatctgtca
     4141 aaaaataagg gacaagcaca cctatccgat tatcatgctg accgggaaag atacagaggt
     4201 agataaaatt acagggttaa caatcggcgc ggatgattat ataacgaagc cctttcgccc
     4261 actggagtta attgctcggg taaaggccca gttgcgccga tacaaaaaat tcagtggagt
     4321 aaaggagcag aacgaaaatg ttatcgtcca ctccggcctt gtcattaatg ttaacaccca
     4381 tgagtgttat ctgaacgaga agcagttatc ccttactccc accgagtttt caatactgcg
     4441 aatcctctgt gaaaacaagg ggaatgtggt tagctccgag ctgctatttc atgagatatg
     4501 gggcgacgaa tatttcagca agagcaacaa caccatcacc gtgcatatcc ggcatttgcg
     4561 cgaaaaaatg aacgacacca ttgataatcc gaaatatata aaaacggtat ggggggttgg
     4621 ttataaaatt gaaaaataaa aaaaacgact attccaaact agaacgaaaa ctttacatgt
     4681 atatcgttgc aattgttgtg gtagcaattg tattcgtgtt gtatattcgt tcaatgatcc
     4741 gagggaaact tggggattgg atcttaagta ttttggaaaa caaatatgac ttaaatcacc
     4801 tggacgcgat gaaattatat caatattcca tacggaacaa tatagatatc tttatttatg
     4861 tggcgattgt cattagtatt cttattctat gtcgcgtcat gctttcaaaa ttcgcaaaat
     4921 actttgacga gataaatacc ggcattgatg tacttattca gaacgaagat aaacaaattg
     4981 agctttctgc ggaaatggat gttatggaac aaaagctcaa cacattaaaa cggactctgg
     5041 aaaagcgaga gcaggatgca aagctggccg aacaaagaaa aaatgacgtt gttatgtact
     5101 tggcgcacga tattaaaacg ccccttacat ccattatcgg ttatttgagc ctgcttgacg
     5161 aggctccaga catgccggta gatcaaaagg caaagtatgt gcatatcacg ttggacaaag
     5221 cgtatcgact cgaacagcta atcgacgagt tttttgagat tacacggtat aacctacaaa
     5281 cgataacgct aacaaaaacg cacatagacc tatactatat gctggtgcag atgaccgatg
     5341 aattttatcc tcagctttcc gcacatggaa aacaggcggt tattcacgcc cccgaggatc
     5401 tgaccgtgtc cggcgaccct gataaactcg cgagagtctt taacaacatt ttgaaaaacg
     5461 ccgctgcata cagtgaggat aacagcatca ttgacattac cgcgggcctc tccggggatg
     5521 tggtgtcaat cgaattcaag aacactggaa gcatcccaaa agataagcta gctgccatat
     5581 ttgaaaagtt ctataggctg gacaatgctc gttcttccga tacgggtggc gcgggacttg
     5641 gattggcgat tgcaaaagaa attattgttc agcatggagg gcagatttac gcggaaagca
     5701 atgataacta tacgacgttt agggtagagc ttccagggtt ctgttgcaaa gttttaaata
     5761 aagaataaaa tccct
//
LOCUS       DACGMI010000179         3774 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.guided.129, whole genome shotgun sequence.
ACCESSION   DACGMI010000179 DACGMI010000000
VERSION     DACGMI010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3774
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.guided.129"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            complement(<1..151)
                     /locus_tag="IXT46_003116"
     CDS             complement(<1..151)
                     /locus_tag="IXT46_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAQ4948950.1"
                     /translation="MKYILSFCTPKLNYLLAYIRLYSGVLHLRDSVRVSEKEKIKVTE
                     MYTSIN"
     gene            381..878
                     /gene="dfrG"
                     /locus_tag="IXT46_003117"
     CDS             381..878
                     /gene="dfrG"
                     /locus_tag="IXT46_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAQ4948951.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(950..2902)
                     /locus_tag="IXT46_003118"
     CDS             complement(950..2902)
                     /locus_tag="IXT46_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAQ4948952.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2909..3205)
                     /locus_tag="IXT46_003119"
     CDS             complement(2909..3205)
                     /locus_tag="IXT46_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4948953.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            complement(3380..>3774)
                     /locus_tag="IXT46_003120"
     CDS             complement(3380..>3774)
                     /locus_tag="IXT46_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAQ4948954.1"
                     /translation="STVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG
                     NDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFY
                     SSTHRGPSELCGNVFKIEYTKKRQRLAY"
BASE COUNT         1160 a          658 c          609 g         1347 t
ORIGIN      
        1 catttattga agtatacatt tctgtaactt ttattttttc tttttctgat actctaaccg
       61 aatctcgtaa atgtagtact ccactataaa ggcgtatata tgcaagtaag tagttcagtt
      121 ttggagtaca aaatgacaaa atgtacttca aaatggacta cttttttcat tttaacttac
      181 ataccaaatt acatacaaaa tgatttataa aatgcaattg aaaatgataa ttgaatgaaa
      241 atttgtgatt ttgtggtatt atgataatat aacttataga aaaaattgct tattcaacta
      301 acgggcagga taatgagaaa aggttttttg atagaaataa gaaattagat ggtaaattag
      361 ttaaaaaggc tgtgttataa atgaaagttt ctttgattgc tgcgatggat aagaatagag
      421 tgattggcaa agagaatgac attccttgga ggattcccaa ggactgggaa tatgttaaaa
      481 atactacaaa gggacatccg ataatattag gtaggaagaa ccttgaatca atcggaagag
      541 ccttacctga cagaagaaat attattctga cgagagataa ggggtttacc tttaatggtt
      601 gtgaaattgt tcattcaata gaagatgttt ttgagttatg taaaaacgaa gaagaaattt
      661 ttattttcgg aggagaacag atttataatt tgtttttccc ttatgttgag aaaatgtaca
      721 tcacaaaaat acatcatgaa ttcgaaggag atactttttt tccagaagtg aattatgagg
      781 aatggaatga ggtatttgcc caaaaaggga taaagaatga taaaaatccg tataactact
      841 attttcatgt atatgaaaga aaaaacttat tgagttaacg ggtgcgttaa ttgaagaaga
      901 acagtaaaga taaagcacaa gagcttggga ttactccaag ctctttttgt catttgaaat
      961 aaattatatc tttccaatca aattgtttat ctgtaatccc taatctttga gcaggtgtca
     1021 aaaccttttt atccgctgat ttaaaagggc gacaaaagtt gtagtaagtt cttagaattg
     1081 taatcgcaaa ttgagcatac ttcggattga agttagcgta aatatagctc ttcttatcac
     1141 cacgagctgt tgttaatggt ctttcaagag atgatatata acgtcttatc tgttgaataa
     1201 agctattggt cgaatggtca ttaacattta atagcatctt tgcgatttcg tttggttcca
     1261 gagcagataa atccgttcta caatcaactg aataaaatcc tttatcctta gtggctaatg
     1321 gatgtttgat agggttatcg gcatatttgc gatatctttc tccatcttta ctaatagcct
     1381 cttcgtggaa ttgatgactt gttagtaatt cagttagata atgagatgcc aaagtccgta
     1441 gaaactttgt tttgaatcct ctgatatctc cccaatcgag cagttctgct tttgcttgtc
     1501 cgaattcttt taagcattgt tttctgcttt tcgtcttgtt aacttggcaa ataaaatgat
     1561 gtgcatcgct caaccttaat tctttcgtga atactctata aaaggcgttt ctaatagaga
     1621 agtcatcatc actaatcatt cgccattcgt cggcattaac catttgttta attaaccaat
     1681 agtgagcagt tgtagtataa ggagcatcaa catttaaacc atcgacaaat ctactcctat
     1741 tagtaatttt ccctaattcg tgaagataag cattcctatt ttcgctatcg ttagcggatg
     1801 gttcttgtgg ataataagac caatctaacc tatcattttt acgactaaaa gtattgagat
     1861 ggtcttcttt gaattttctt gtatcttcat ttaattcatc cattgaaata ttccaatcat
     1921 aggcaacatc agaacggaac acatatcttg ataagacctc agcagataca actatatacg
     1981 tttgcatatt aaggtcttca aaccccgtat atttctttga accttgtcct ttcttacgga
     2041 cgttatttag gtagtagtgc atcttgtccg tattaagcca catctcgtta aatttctttg
     2101 tttgaagggg ttgtgtctca tatcgttcta aaaactccaa acaacgccta tacagccact
     2161 ccagcttatg atagtaggtt ccaactccaa ttcctaaaat atcacaagta cgactgactg
     2221 aaacccttcc aacaaccatc ttagcgaaca ttggaagaat ggtgttcttt tgttggtgat
     2281 aagtagtggt ttcttctctt tttggtagaa cattagtgaa cttcttacac gccttacatt
     2341 gatagcgttg agatttgccc ctacttttcc cccttttgta aaattgcttc ggctcattga
     2401 atggggttga ttcttcttcc gagcagcctt ctttatgaaa ttgataatct ggctcaacat
     2461 cttggatgct attgatttct ataaggcgtt taatttcttc aacaacagac caattagata
     2521 aaggggttac tgtacagttt tgcgatacac ctctgccaat aggattgtca ttgcagtaca
     2581 tacctttatg acctttatct ttggaactac cagtcatttt atatcgactt ggtttccctt
     2641 ttacatcttt gaatttgtgc tgttctttcc caaaattaca acaaaacgga ttgatgcagt
     2701 aattatattg aatgggatat tcagaaccgt tccatttaaa agacgttggc aagaacaaca
     2761 ttttgttata ccttgttgca aatcgttttg gagttaataa atcatattgt ttagccctat
     2821 cttttaattc ttcgtttgaa atcggaattt taacatctac aatttcatct tccttcgtgg
     2881 ctaatctttt aagcttggtc attgtctatc aacccactct atctttgata cccatttttt
     2941 caacaatccg cttattactt cgcttgttgg caatccattc aataaacttc ttatcgtcta
     3001 aaatgttcaa taagaattca tccactgctt cgctttcagt acgctctgca tattcagcgt
     3061 attgcttaac tatcaccctt acttgctctg atatttccca atccacagac ttagcgttct
     3121 tattttttgg ctcaagaaat tgcataggaa aatgcacccc tttttgctta gtaaattgta
     3181 accattttaa cacaccaatt tgcattccta caataattat ttcacgttcg catttttata
     3241 tacattttaa cttacatttt gtggtgtaaa ttaacaacaa acgttgattt aacaataaaa
     3301 aacgagtatc aaattcagtt gcaatttgat actcatttag gtttacattt tcactttttg
     3361 tactccaaaa ctgaactact taatatgcaa gacgttgtct tttttttgta tattcaattt
     3421 tgaaaacatt tccgcaaagt tcagacggac ctcgatgtgt tgatgaataa aatttattag
     3481 taataacttc tataaggtta tcaatcccta tattactttt tgcacttcca tgataaagag
     3541 ggaacagaga acaattctga aatcttatgc tttcctcttg ttcgagttcc aatgcttcta
     3601 atgatttacc ggacatatat ttctctaaaa ggtcatcgtt tccctctatt accgtatccc
     3661 attgttcaga ttcggtaaag ttcgtcacac acatattagg atacagttct accttctgtt
     3721 tgattacaat ttcggcagaa agtttctctt taatatcctg ataaaccgtt gata
//
LOCUS       DACGMI010000180         3720 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.guided.130, whole genome shotgun sequence.
ACCESSION   DACGMI010000180 DACGMI010000000
VERSION     DACGMI010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.guided.130"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            554..640
                     /locus_tag="IXT46_003121"
                     /pseudo
     CDS             554..640
                     /locus_tag="IXT46_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011058339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance protein"
     gene            641..2581
                     /gene="tet(S)"
                     /locus_tag="IXT46_003122"
     CDS             641..2581
                     /gene="tet(S)"
                     /locus_tag="IXT46_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HAQ4948955.1"
                     /translation="MEEIKLKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSG
                     TTKTDTMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAIL
                     LISAKDGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIK
                     QTVNLNLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSL
                     YPVYHGSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLY
                     SGTLHLRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGD
                     KKRLPHREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIV
                     LSFLGEVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASI
                     GLSVTPLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKY
                     GLYYSPVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKY
                     CANILNTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAF
                     QPRRPNNRIDKVRHMFNKINLH"
     gene            2669..2836
                     /locus_tag="IXT46_003123"
     CDS             2669..2836
                     /locus_tag="IXT46_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4948956.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITV
                     ITEPDAKTQSR"
     gene            complement(3350..3706)
                     /locus_tag="IXT46_003124"
     CDS             complement(3350..3706)
                     /locus_tag="IXT46_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009009558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4948957.1"
                     /translation="MWQTTLSNFDFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLT
                     NIENKGQQPSFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVT
                     IGKVIQAIYGEKCKFN"
BASE COUNT         1327 a          577 c          618 g         1198 t
ORIGIN      
        1 tatttgatag tagatttaaa actttgcaac agaacccttt taatgatatt ttccaagtca
       61 aacttaatat taacaattca aaactattgg aaccactgca aaatattttg ttaagcagta
      121 tatatttcaa aaattatacg taatatattt gtagaaaggt tgtggacagt tgtcctattg
      181 acctgaaaag taatataata gctggatgaa taaagaatcc cttatgaact tgtaaatcgt
      241 tattaaatcg ctgaattttg atagccattc tgaagagtta tcttcaacta ctacactaac
      301 ttccattaat ttctcattaa tttccctttc gttcaaaaaa tatggttggc tttacaagca
      361 ttctatcata tgatagaatt aagataacat tcaaaaggag ataataaaaa tgcggcaagg
      421 tattcttaaa taaactgtca attagatagc gggaataatt aattaagcat ccttatttaa
      481 aataaggact ggttttttgt gcccagttta agaatacttt tatcatttta tcataaagca
      541 tctgtggcta tcagtgtgta gtatacagct atttttgtat taaaatccca gtgataagag
      601 tatttatcac tgggattttt tctgcttttt gagcttttga atggaggaaa taaaattgaa
      661 aattattaat atcggtatct tagcacatgt tgatgcagga aaaactactt tgacagaaag
      721 cttactatac agtagcggag caattaaaga gttaggaagt gtagatagcg gtacaacgaa
      781 aacggatact atgtttttgg aacgccagag aggtattact attcagaccg caataacatc
      841 ttttcaacgg gaaaatgtta aagtaaatat tgtagatact cctggacaca tggatttttt
      901 ggcagatgta taccgttcat tatctgtttt ggatggagct attttgctaa tctctgcaaa
      961 agatggagta cagtcacaaa ctcgtatact attccatgca cttagaaaga tgaacatacc
     1021 tataatattt tttattaaca aaattgatca aaatggaata aatttgccag atgtttatca
     1081 agatattaag gacaaacttt ctgacgacat cataattaag cagactgtga atctaaattt
     1141 gaaaccttat gtaatagatt atactgaacc agaacaatgg gagacagtaa ttgtgggaaa
     1201 tgattattta ttagaaaaat ataccattgg gaaaacattg aatattgcag aacttgaaaa
     1261 ggaggaaaac gaaagaattc aaagttgctc cttatatcct gtttatcacg gaagtgcaaa
     1321 gaataatatt ggaattaaac aacttataga ggtaattact agcaaattat tttcacccac
     1381 acaactcaat tcagataaac tttgtggaaa tgtttttaaa gtagaatatt cagatgatgg
     1441 tcaacggctt gtctatgtac gtctttatag tggaacgcta catttgcgag actcagtcaa
     1501 tatatcagaa aaggaaaaaa taaaagttac agaaatgtat acttcaataa atggagaatt
     1561 acgccagata gataaggcag agcctggtga gattattatt ttaaaaaatg agcttttaaa
     1621 actaaataac gtacttggag ataaaaaaag attaccacat agagaaattc ttgagaatcc
     1681 tcttcctatg ttacaaacaa caattgaacc atgtaaatca gtacaaagag aaaagttact
     1741 agatgcactt tttgaaatat ccgatagtga tccccttcta caatattatg tagatacagt
     1801 aactcacgaa attgtgctat cttttttagg tgaggtccaa atggaggtaa cttgtactct
     1861 gattcaagaa aaatatcata ttgagataga aacaagaaaa ccaactgtca tttatatgga
     1921 aagaccatta aaaaaatctg aatttaccat tgatatcgaa gtacctccaa atcctttctg
     1981 ggcttctatt ggtttatctg taacaccact tcctttgggt agtggcattc agtatgagag
     2041 cctggtttct ctaggttatt taaatcaatc atttcaaaat gcagttatgg aaggtatacg
     2101 ctatgggtgt gaacaaggat tgtacggttg gaaattaaca gactgtaaga tctgttttaa
     2161 gtatggtcta tattacagcc ctgtcagtac gccagcagat ttccgaatgc ttgcgcctat
     2221 tgtactagag caggctttta gaaagagtgg tacagagtta ttagagccat atcttagctt
     2281 cgaaatttat gtaccacaag aatatctttc gagagcatat aatgatgctt ccaaatattg
     2341 tgcaaatatt ttaaatacta agttaaaagg taacgaggtc attctcattg gtgaaattcc
     2401 agcccgttgt attcaagagt atcgaaacag tttaactttc tttacaaatg gacgcagtgt
     2461 ctgtttaaca gagttaaaag gttatcaggt tactaacatt aagtctgctt tccaaccacg
     2521 tcgtccaaat aatagaatag acaaagtaag gcatatgttt aataaaatca acttacattg
     2581 atagtgaact aaagagaaat ttttaaaatg aatattgagt tgttaattag aacaggagga
     2641 tatagatatt gtaaatacta ggtggatact gtgccctata tgtggcaata agacccgttt
     2701 aaaaatgagg gaagatactg aattaaaaaa tttccctcta ttttgtccta aatgcagaca
     2761 agaaatttta attgaaataa cgaagtttag aataactgta attacagagc cagacgcaaa
     2821 gacgcagagc cgataattcg agatatcaaa atctcatttt atcggctttt tcttttctat
     2881 gcataccatt gagcttagtt cttgatatcc tttataagaa aataagtgta ctgatttttt
     2941 ttgcagtagc tgtattacag tagacatccc tcaagcataa aaagtataca attaaaattc
     3001 aatacttgat tattgatgaa gtacagagtt actcgtcatt tcaaaactag tatatcagtc
     3061 aagtttttcc taaggaacaa aaacgaactt cgctatggga atcaaaaatt tttagtcgga
     3121 tgaagtgata tgcaataaat ccagaaaatt ttcccaacaa caaaaaatga actgtacttt
     3181 gcagcgataa gagtaaccaa agaactattt atcattcgct ctagttccta agtgtaacaa
     3241 agataaattc attttctatt tatgattaac aaaaatcaga aaaaattcat tacatctttg
     3301 taatcaatct ttcctgatag tattaattaa tccattgtgt attattgaac tagttaaatt
     3361 tacatttttc tccgtaaatt gcttgaatca ctttcccaat cgtcactaat tcatcttcat
     3421 ccagacaatc caactgtgct tctacttgaa gacgtttgga gcttttatga ctgttttctt
     3481 cccctaaaat aaatccatcc aaagaaatat ttagcaaagt cactaaatca tatacaacat
     3541 gaaaacttgg ctgttgtcct ttattttcaa tgttcgtcaa atagcgtggc gcaatctgga
     3601 tcattgatcc tacctgctca cgagtcaatc ctttactaag acgggcttct ttaatcgcaa
     3661 gacccaatgg tttgaaatca aaatttgata gagtagtttg ccatattctt gcacccaacg
//
LOCUS       DACGMI010000181         2950 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.guided.137, whole genome shotgun sequence.
ACCESSION   DACGMI010000181 DACGMI010000000
VERSION     DACGMI010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.guided.137"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            297..1265
                     /locus_tag="IXT46_003125"
     CDS             297..1265
                     /locus_tag="IXT46_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAQ4948958.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1258..2289
                     /gene="vanA"
                     /locus_tag="IXT46_003126"
     CDS             1258..2289
                     /gene="vanA"
                     /locus_tag="IXT46_003126"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAQ4948959.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2295..2903
                     /locus_tag="IXT46_003127"
     CDS             2295..2903
                     /locus_tag="IXT46_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAQ4948960.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          876 a          563 c          714 g          797 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaaccg cttccagcga tgccagactt
       61 ggttgataaa aggaggtcct aagagatgta tataattttt taggaaaatc tcaaggttat
      121 ctttactttt tcttaggaaa ttaacaattt aatattaaga aacggctcgt tcttacacgg
      181 tagacttaat accgtaagaa cgagccgttt tcgttcttca gagaaagatt tgacaagatt
      241 accattggca tccccgtttt atttggtgcc tttcacagaa agggttggtc ttaattatga
      301 ataacatcgg cattactgtt tatggatgtg agcaggatga ggcagatgca ttccatgctc
      361 tttcgcctcg ctttggcgtt atggcaacga taattaacgc caacgtgtcg gaatccaacg
      421 ccaaatccgc gcctttcaat caatgtatca gtgtgggaca taaatcagag atttccgcct
      481 ctattcttct tgcgctgaag agagccggtg tgaaatatat ttctacccga agcatcggct
      541 gcaatcatat agatacaact gctgctaaga gaatgggcat cactgtcgac aatgtggcgt
      601 actcgccgga tagcgttgcc gattatacta tgatgctaat tcttatggca gtacgcaacg
      661 taaaatcgat tgtgcgctct gtggaaaaac atgatttcag gttggacagc gaccgtggca
      721 aggtactcag cgacatgaca gttggtgtgg tgggaacggg ccagataggc aaagcggtta
      781 ttgagcggct gcgaggattt ggatgtaaag tgttggctta tagtcgcagc cgaagtatag
      841 aggtaaacta tgtaccgttt gatgagttgc tgcaaaatag cgatatcgtt acgcttcatg
      901 tgccgctcaa tacggatacg cactatatta tcagccacga acaaatacag agaatgaagc
      961 aaggagcatt tcttatcaat actgggcgcg gtccacttgt agatacctat gagttggtta
     1021 aagcattaga aaacgggaaa ctgggcggtg ccgcattgga tgtattggaa ggagaggaag
     1081 agtttttcta ctctgattgc acccaaaaac caattgataa tcaattttta cttaaacttc
     1141 aaagaatgcc taacgtgata atcacaccgc atacggccta ttataccgag caagcgttgc
     1201 gtgataccgt tgaaaaaacc attaaaaact gtttggattt tgaaaggaga caggagcatg
     1261 aatagaataa aagttgcaat actgtttggg ggttgctcag aggagcatga cgtatcggta
     1321 aaatctgcaa tagagatagc cgctaacatt aataaagaaa aatacgagcc gttatacatt
     1381 ggaattacga aatctggtgt atggaaaatg tgcgaaaaac cttgcgcgga atgggaaaac
     1441 gacaattgct attcagctgt actctcgccg gataaaaaaa tgcacggatt acttgttaaa
     1501 aagaaccatg aatatgaaat caaccatgtt gatgtagcat tttcagcttt gcatggcaag
     1561 tcaggtgaag atggatccat acaaggtctg tttgaattgt ccggtatccc ttttgtaggc
     1621 tgcgatattc aaagctcagc aatttgtatg gacaaatcgt tgacatacat cgttgcgaaa
     1681 aatgctggga tagctactcc cgccttttgg gttattaata aagatgatag gccggtggca
     1741 gctacgttta cctatcctgt ttttgttaag ccggcgcgtt caggctcatc cttcggtgtg
     1801 aaaaaagtca atagcgcgga cgaattggac tacgcaattg aatcggcaag acaatatgac
     1861 agcaaaatct taattgagca ggctgtttcg ggctgtgagg tcggttgtgc ggtattggga
     1921 aacagtgccg cgttagttgt tggcgaggtg gaccaaatca ggctgcagta cggaatcttt
     1981 cgtattcatc aggaagtcga gccggaaaaa ggctctgaaa acgcagttat aaccgttccc
     2041 gcagaccttt cagcagagga gcgaggacgg atacaggaaa cggcaaaaaa aatatataaa
     2101 gcgctcggct gtagaggtct agcccgtgtg gatatgtttt tacaagataa cggccgcatt
     2161 gtactgaacg aagtcaatac tctgcccggt ttcacgtcat acagtcgtta tccccgtatg
     2221 atggccgctg caggtattgc acttcccgaa ctgattgacc gcttgatcgt attagcgtta
     2281 aaggggtgat aagcatggaa ataggattta cttttttaga tgaaatagta cacggtgttc
     2341 gttgggacgc taaatatgcc acttgggata atttcaccgg aaaaccggtt gacggttatg
     2401 aagtaaatcg cattgtaggg acatacgagt tggctgaatc gcttttgaag gcaaaagaac
     2461 tggctgctac ccaagggtac ggattgcttc tatgggacgg ttaccgtcct aagcgtgctg
     2521 taaactgttt tatgcaatgg gctgcacagc cggaaaataa cctgacaaag gaaagttatt
     2581 atcccaatat tgaccgaact gagatgattt caaaaggata cgtggcttca aaatcaagcc
     2641 atagccgcgg cagtgccatt gatcttacgc tttatcgatt agacacgggt gagcttgtac
     2701 caatggggag ccgatttgat tttatggatg aacgctctca tcatgcggca aatggaatat
     2761 catgcaatga agcgcaaaat cgcagacgtt tgcgctccat catggaaaac agtgggtttg
     2821 aagcatatag cctcgaatgg tggcactatg tattaagaga cgaaccatac cccaatagct
     2881 attttgattt ccccgttaaa taaactttta acggttctgt tgcaaagttt taaataaaga
     2941 ataaaatccc
//
LOCUS       DACGMI010000182         2371 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.guided.143, whole genome shotgun sequence.
ACCESSION   DACGMI010000182 DACGMI010000000
VERSION     DACGMI010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.guided.143"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="IXT46_003128"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="IXT46_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAQ4948961.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2060..2227
                     /locus_tag="IXT46_003129"
     CDS             2060..2227
                     /locus_tag="IXT46_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4948962.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(2287..>2371)
                     /locus_tag="IXT46_003130"
     CDS             complement(2287..>2371)
                     /locus_tag="IXT46_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4948963.1"
                     /translation="MDSFTDKELSLMESLASGINEARNIED"
BASE COUNT          810 a          367 c          482 g          712 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acagaggtac aacgaaaacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacggcgat aacctctttt cagtggaaaa atactaagat aaacatcata
      241 gacacgccag gacatatgga ttttttagca gaagtatatc gttcattatc agtattagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattgttt
      361 catgcactta ggaaaatagg tattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc ggaaattgta
      481 atcaaacaga aggtagaact gcatcctaat atgcgtgtaa tgaactttac cgaatctgaa
      541 caatgggata tggtaataga aggaaatgat taccttttgg agaaatatac gtctgggaaa
      601 ttattggaag cattagaact cgaacaagag gaaagcataa gatttcataa ttgttccctg
      661 ttccctgttt atcacggaag tgcaaaaaac aatataggga ttgataacct tatagaagtg
      721 attacgaata aattttattc atcaacacat cgaggtcagt ctgaactttg cggaaaagtt
      781 ttcaaaattg agtattcgga aaaaagacag cgtcttgcat atatacgtct ttatagtggc
      841 gtactgcatt tgcgagattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaatcgata aggcttattc cggggaaatt
      961 gttattttgc agaatgagtt tttgaagtta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatcccctc cctctgctgc aaacgactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctgcgat attatgtgga ttctgcgaca catgaaatca tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgacttg tgctctgctg caagaaaagt atcatgtgga gatagaaata
     1261 aaagagccta cagtcattta tatggaaaga ccgttaaaaa aagcagagta taccattcac
     1321 atcgaagttc caccgaatcc tttctgggct tccattggtc tatctgtagc accgcttcca
     1381 ttagggagcg gagtacagta tgagagctcg gtttctcttg gatacttaaa tcaatcgttt
     1441 caaaatgcag ttatggaggg gatacgctat ggctgtgaac aaggattgta tggttggaat
     1501 gtgacggact gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg agatagttat
     2041 tataaactac aagtggatat tgtgtcctgt atgtggaaat aaaacacgat taaagataag
     2101 ggaagatact gaattaaaaa aattccccct ctattgtccg aaatgcagac aagaaaattt
     2161 aattgaaata aagcagttca aagtaactgt gattacagag ccagacgcaa agacgcagag
     2221 ccgataaaat gagattaata caatctcatt ttatcggctc tttccgttat gtatggattc
     2281 ttttaattag tcttcgatgt ttcttgcttc gttgataccg ctggctaaag attccattaa
     2341 ggatagttct ttgtctgtaa agctatccat g
//
LOCUS       DACGMI010000183         2014 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.guided.148, whole genome shotgun sequence.
ACCESSION   DACGMI010000183 DACGMI010000000
VERSION     DACGMI010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.guided.148"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            216..1127
                     /locus_tag="IXT46_003131"
     CDS             216..1127
                     /locus_tag="IXT46_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HAQ4948964.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1280..1765
                     /gene="vanZ"
                     /locus_tag="IXT46_003132"
     CDS             1280..1765
                     /gene="vanZ"
                     /locus_tag="IXT46_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAQ4948965.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
BASE COUNT          716 a          275 c          386 g          637 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccgt atcacttatg aaaattcatc
       61 tacattggtg ataatagtaa atccagtagg gcgaaataat tgactgtaat ttacggggca
      121 aaacggcaca atctcaaacg agattgtgcc gtttaagggg aagattctag aaatatttca
      181 tacttccaac tatatagtta aggaggagac tgaaaatgaa gaagttgttt tttttattgt
      241 tattgttatt cttaatatac ttaggttatg actacgttaa tgaagcactg ttttctcagg
      301 aaaaagtcga atttcaaaat tatgatcaaa atcccaaaga acatttagaa aatagtggga
      361 cttctgaaaa tacccaagag aaaacaatta cagaagaaca ggtttatcaa ggaaatctgc
      421 tattaatcaa tagtaaatat cctgttcgcc aagaaagtgt gaagtcagat atcgtgaatt
      481 tatctaaaca tgacgaatta ataaatggat acgggttgct tgatagtaat atttatatgt
      541 caaaagaaat agcacaaaaa ttttcagaga tggtcaatga tgctgtaaag ggtggcgtta
      601 gtcattttat tattaatagt ggctatcgag actttgatga gcaaagtgtg ctttaccaag
      661 aaatgggggc tgagtatgcc ttaccagcag gttatagtga gcataattca ggtttatcac
      721 tagatgtagg atcaagcttg acgaaaatgg aacgagcccc tgaaggaaag tggatagaag
      781 aaaatgcttg gaaatacggg ttcattttac gttatccaga ggacaaaaca gagttaacag
      841 gaattcaata tgaaccatgg catattcgct atgttggttt accacatagt gcgattatga
      901 aagaaaagaa tttcgttctc gaggaatata tggattacct aaaagaagaa aaaaccattt
      961 ctgttagtgt aaatggggaa aaatatgaga tcttttatta tcctgttact aaaaatacca
     1021 ccattcatgt gccgactaat cttcgttatg agatatcagg aaacaatata gacggtgtaa
     1081 ttgtgacagt gtttcccgga tcaacacata ctaattcaag gaggtaagga tggcggaatg
     1141 aaaccaacga aattaatgaa cagcattatt gtactagcac ttttggggta acgttagctt
     1201 tttaatttaa aacccacgtt aactaggaca ttgctatact aatgatacaa cttaaacaaa
     1261 agaattagag gaaattatat tgggaaaaat attatctaga ggattgctag ctttatattt
     1321 agtgacacta atctggttag tgttattcaa attacaatac aatattttat cagtatttaa
     1381 ttatcatcaa agaagtctta acttgactcc atttactgct actgggaatt tcagagagat
     1441 gatagataat gttataatct ttattccatt tggcttgctt ttgaatgtca attttaaaga
     1501 aatcggattt ttacctaagt ttgcttttgt actggtttta agtcttactt ttgaaataat
     1561 tcaatttatc ttcgctattg gagcgacaga cataacagat gtaattacaa atactgttgg
     1621 aggctttctt ggactgaaat tatatggttt aagcaataag catatgaatc aaaaaaaatt
     1681 agacagagtt attatttttg taggtatact tttgctcgta ttattgctcg tttaccgtac
     1741 ccatttaaga ataaattacg tgtaagatgt ctaaatcaag caatctgatc tttcatacac
     1801 ataaagatat tgaatgaatt ggattagatg gaaaacggga tgtggggaaa ctcgcccgta
     1861 ggtgtgaagt gaggggaaaa ccggtgataa agtaaaaagc ttacctaaca ctatagtaac
     1921 aaagaaagcc caattatcaa ttttagtgct gaggaattgg tctctttaat aaatttggtt
     1981 ctgttgcaaa gttttaaatc tactatcaaa taag
//
LOCUS       DACGMI010000184         1477 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0381
            SAMEA3304412-rid9553043.guided.157, whole genome shotgun sequence.
ACCESSION   DACGMI010000184 DACGMI010000000
VERSION     DACGMI010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304412
            Sequence Read Archive: ERR985030
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702191.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702191.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 20:26:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,135
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 3,016
            CDSs (with protein)               :: 3,016
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 29 of 64
            Pseudo Genes (internal stop)      :: 20 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1477
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304412-rid9553043.guided.157"
                     /strain="VREN0381"
                     /db_xref="taxon:1352"
     gene            9..1049
                     /locus_tag="IXT46_003133"
     CDS             9..1049
                     /locus_tag="IXT46_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAQ4948966.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            1147..1335
                     /locus_tag="IXT46_003134"
     CDS             1147..1335
                     /locus_tag="IXT46_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4948967.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(1393..>1477)
                     /locus_tag="IXT46_003135"
     CDS             complement(1393..>1477)
                     /locus_tag="IXT46_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4948968.1"
                     /translation="MDSFTDKELSLMEALAKGINEARNIEG"
BASE COUNT          489 a          231 c          282 g          475 t
ORIGIN      
        1 ttacagaaat gtatacttca ataaatggtg aattatgtaa gattgataga gcttattctg
       61 gagaaattgt tattttgcaa aatgagtttt tgaagttaaa tagtgttctt ggagatacaa
      121 aactattgcc acagagaaaa aagattgaaa atccgcaccc tctactacaa acaactgttg
      181 aaccgagtaa acctgaacag agagaaatgt tgcttgatgc ccttttggaa atctcagata
      241 gtgatccgct tctacgatat tacgtggatt ctacgacaca tgaaattata ctttctttct
      301 tagggaaagt acaaatggaa gtgattagtg cactgttgca agaaaagtat catgtggaga
      361 tagaactaaa agagcctaca gtcatttata tggagagacc gttaaaaaat gcagaatata
      421 ccattcacat cgaagtgccg ccaaatcctt tctgggcttc cattggttta tctgtatcac
      481 cgcttccgtt gggaagtgga atgcagtatg agagctcggt ttctcttgga tacttaaatc
      541 aatcatttca aaatgcagtt atggaaggga tacgctatgg ttgcgaacaa ggattatatg
      601 gttggaatgt gacggattgt aaaatctgtt ttaagtacgg tttatactat agccctgtta
      661 gtactccagc agattttcgg atgcttactc ctattgtact ggagcaagcc tttagaaaag
      721 ctggaacaga attgttagag ccatatctta gttttaaagt ttatgcacca caggaatatc
      781 tttcacgggc atataacgat gctcccaaat attgtgcaaa tatcgtaaat actcaactga
      841 aaaataatga ggtcattatt attggagaaa ttcctgctcg atgtattcaa gattatcgca
      901 atgatttaac tttttttaca aatgggctta gtgtttgttt agcagagcta aaaggatatc
      961 aggttaccac tggcgaacct gtttgccaga cccgtcgtct aaatagtcgg atagataaag
     1021 taagatatat gttcaataaa ataacttagt gcgttttatg ttgttatata aatatggttt
     1081 cttattaaat aagatgaaat attctttaat atagatttga attaaagtgg aaaggaggag
     1141 attgttatta taaactacaa gtggatattg tgtcctattt gtggaaataa aacaagacta
     1201 cgaatacgag tggatactat acttaaaaat ttccctttat actgccccaa atgtaagaac
     1261 gaaactttaa ttaatgttca aaaaatgaat ataataacaa tcaaagagcc agacgccaag
     1321 acgcagagcc gataatttga gaaatgaaac tctcatctta tcggctcttt ttgtttatct
     1381 gaattttact gactagcctt caatatttct tgcttcattg ataccttttg ctagtgcttc
     1441 cattaaggat agttctttgt ctgtaaagct atccatg
//
